AFULGI_00002300 be5ab75a73696119d4779ed037bfbd2b 409 Gene3D G3DSA:1.10.8.60 13 284 2.6E-106 T 01-11-2018 AFULGI_00002300 be5ab75a73696119d4779ed037bfbd2b 409 SUPERFAMILY SSF52540 13 280 2.09E-56 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00002300 be5ab75a73696119d4779ed037bfbd2b 409 SMART SM01074 301 382 4.5E-34 T 01-11-2018 IPR015163 Cdc6, C-terminal Reactome: R-HSA-176187|Reactome: R-HSA-539107|Reactome: R-HSA-68689|Reactome: R-HSA-68827|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962 AFULGI_00002300 be5ab75a73696119d4779ed037bfbd2b 409 Pfam PF09079 CDC6, C terminal winged helix domain 305 380 3.3E-24 T 01-11-2018 IPR015163 Cdc6, C-terminal Reactome: R-HSA-176187|Reactome: R-HSA-539107|Reactome: R-HSA-68689|Reactome: R-HSA-68827|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962 AFULGI_00002300 be5ab75a73696119d4779ed037bfbd2b 409 Pfam PF13401 AAA domain 52 161 5.5E-12 T 01-11-2018 IPR003593 AAA+ ATPase domain AFULGI_00002300 be5ab75a73696119d4779ed037bfbd2b 409 Gene3D G3DSA:1.10.10.10 293 392 4.3E-32 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00002300 be5ab75a73696119d4779ed037bfbd2b 409 TIGRFAM TIGR02928 TIGR02928: orc1/cdc6 family replication initiation protein 13 371 1.8E-146 T 01-11-2018 IPR014277 Orc1/Cdc6-type DNA replication protein, archaea AFULGI_00002300 be5ab75a73696119d4779ed037bfbd2b 409 Gene3D G3DSA:3.40.50.300 29 205 2.6E-106 T 01-11-2018 AFULGI_00002300 be5ab75a73696119d4779ed037bfbd2b 409 SUPERFAMILY SSF46785 286 391 3.26E-29 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00002300 be5ab75a73696119d4779ed037bfbd2b 409 SMART SM00382 51 207 2.1E-12 T 01-11-2018 IPR003593 AAA+ ATPase domain AFULGI_00002300 be5ab75a73696119d4779ed037bfbd2b 409 Hamap MF_01407 ORC1-type DNA replication protein. 6 382 32.446 T 01-11-2018 IPR014277 Orc1/Cdc6-type DNA replication protein, archaea AFULGI_00000500 c41fbbbbacdd9897084d1a31cb4f364b 83 Pfam PF01780 Ribosomal L37ae protein family 3 82 6.6E-32 T 01-11-2018 IPR002674 Ribosomal protein L37ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFULGI_00000500 c41fbbbbacdd9897084d1a31cb4f364b 83 TIGRFAM TIGR00280 eL43_euk_arch: ribosomal protein eL43 1 82 1.6E-41 T 01-11-2018 IPR002674 Ribosomal protein L37ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFULGI_00000500 c41fbbbbacdd9897084d1a31cb4f364b 83 SUPERFAMILY SSF57829 10 80 8.55E-27 T 01-11-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 AFULGI_00000500 c41fbbbbacdd9897084d1a31cb4f364b 83 Gene3D G3DSA:2.20.25.30 9 83 1.5E-29 T 01-11-2018 IPR011331 Ribosomal protein L37ae/L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFULGI_00000500 c41fbbbbacdd9897084d1a31cb4f364b 83 Hamap MF_00327 50S ribosomal protein L37Ae [rpl37ae]. 3 71 23.013 T 01-11-2018 IPR002674 Ribosomal protein L37ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFULGI_00003220 50d4cebae0fa8ec9437df61f0efe88f5 352 TIGRFAM TIGR01208 rmlA_long: glucose-1-phosphate thymidylyltransferase 2 352 2.3E-171 T 01-11-2018 IPR005908 Glucose-1-phosphate thymidylyltransferase, long form AFULGI_00003220 50d4cebae0fa8ec9437df61f0efe88f5 352 SUPERFAMILY SSF53448 2 301 2.48E-76 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFULGI_00003220 50d4cebae0fa8ec9437df61f0efe88f5 352 Gene3D G3DSA:3.90.550.10 1 244 8.4E-72 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFULGI_00003220 50d4cebae0fa8ec9437df61f0efe88f5 352 Gene3D G3DSA:2.160.10.10 245 351 2.6E-7 T 01-11-2018 AFULGI_00003220 50d4cebae0fa8ec9437df61f0efe88f5 352 Pfam PF00483 Nucleotidyl transferase 2 236 1.7E-60 T 01-11-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 AFULGI_00013230 a51eeb9d888e3e8a6ef5625cd9580372 182 TIGRFAM TIGR00295 TIGR00295: TIGR00295 family protein 7 178 2.0E-87 T 01-11-2018 IPR004454 HD-related protein AFULGI_00013230 a51eeb9d888e3e8a6ef5625cd9580372 182 Gene3D G3DSA:1.10.3210.10 2 176 1.1E-16 T 01-11-2018 AFULGI_00013230 a51eeb9d888e3e8a6ef5625cd9580372 182 TIGRFAM TIGR00277 HDIG: HDIG domain 17 96 3.7E-21 T 01-11-2018 IPR006675 HDIG domain AFULGI_00013230 a51eeb9d888e3e8a6ef5625cd9580372 182 Pfam PF01966 HD domain 22 132 1.0E-18 T 01-11-2018 IPR006674 HD domain AFULGI_00013230 a51eeb9d888e3e8a6ef5625cd9580372 182 SUPERFAMILY SSF109604 16 169 5.16E-23 T 01-11-2018 AFULGI_00013230 a51eeb9d888e3e8a6ef5625cd9580372 182 SMART SM00471 16 142 7.1E-15 T 01-11-2018 IPR003607 HD/PDEase domain AFULGI_00012450 78cc056a858a2ced0bcbafe586974e94 406 PIRSF PIRSF000724 1 404 5.1E-129 T 01-11-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFULGI_00012450 78cc056a858a2ced0bcbafe586974e94 406 Gene3D G3DSA:3.40.50.1260 190 387 5.4E-114 T 01-11-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFULGI_00012450 78cc056a858a2ced0bcbafe586974e94 406 SUPERFAMILY SSF53748 5 397 1.77E-108 T 01-11-2018 IPR036043 Phosphoglycerate kinase superfamily GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFULGI_00012450 78cc056a858a2ced0bcbafe586974e94 406 PRINTS PR00477 Phosphoglycerate kinase family signature 194 213 4.6E-59 T 01-11-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFULGI_00012450 78cc056a858a2ced0bcbafe586974e94 406 PRINTS PR00477 Phosphoglycerate kinase family signature 12 28 4.6E-59 T 01-11-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFULGI_00012450 78cc056a858a2ced0bcbafe586974e94 406 PRINTS PR00477 Phosphoglycerate kinase family signature 318 343 4.6E-59 T 01-11-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFULGI_00012450 78cc056a858a2ced0bcbafe586974e94 406 PRINTS PR00477 Phosphoglycerate kinase family signature 373 390 4.6E-59 T 01-11-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFULGI_00012450 78cc056a858a2ced0bcbafe586974e94 406 PRINTS PR00477 Phosphoglycerate kinase family signature 33 55 4.6E-59 T 01-11-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFULGI_00012450 78cc056a858a2ced0bcbafe586974e94 406 PRINTS PR00477 Phosphoglycerate kinase family signature 142 164 4.6E-59 T 01-11-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFULGI_00012450 78cc056a858a2ced0bcbafe586974e94 406 PRINTS PR00477 Phosphoglycerate kinase family signature 107 122 4.6E-59 T 01-11-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFULGI_00012450 78cc056a858a2ced0bcbafe586974e94 406 PRINTS PR00477 Phosphoglycerate kinase family signature 172 194 4.6E-59 T 01-11-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFULGI_00012450 78cc056a858a2ced0bcbafe586974e94 406 PRINTS PR00477 Phosphoglycerate kinase family signature 350 361 4.6E-59 T 01-11-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFULGI_00012450 78cc056a858a2ced0bcbafe586974e94 406 Gene3D G3DSA:3.40.50.1260 14 393 5.4E-114 T 01-11-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFULGI_00012450 78cc056a858a2ced0bcbafe586974e94 406 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 17 27 - T 01-11-2018 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFULGI_00012450 78cc056a858a2ced0bcbafe586974e94 406 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 7 397 33.877 T 01-11-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFULGI_00012450 78cc056a858a2ced0bcbafe586974e94 406 Pfam PF00162 Phosphoglycerate kinase 9 386 1.4E-104 T 01-11-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFULGI_00002310 28a957eb40dc267d83db8fdc7dab2a86 209 Gene3D G3DSA:2.30.30.90 138 208 2.4E-10 T 01-11-2018 IPR038157 Ferrous iron transporter, core domain AFULGI_00002310 28a957eb40dc267d83db8fdc7dab2a86 209 SMART SM00899 138 207 7.8E-12 T 01-11-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 AFULGI_00002310 28a957eb40dc267d83db8fdc7dab2a86 209 SUPERFAMILY SSF47979 55 129 2.09E-23 T 01-11-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 AFULGI_00002310 28a957eb40dc267d83db8fdc7dab2a86 209 Pfam PF04023 FeoA domain 139 205 4.3E-9 T 01-11-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 AFULGI_00002310 28a957eb40dc267d83db8fdc7dab2a86 209 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 55 121 9.4E-26 T 01-11-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 AFULGI_00002310 28a957eb40dc267d83db8fdc7dab2a86 209 SMART SM00529 18 113 1.1E-34 T 01-11-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 AFULGI_00002310 28a957eb40dc267d83db8fdc7dab2a86 209 SUPERFAMILY SSF50037 140 205 5.72E-9 T 01-11-2018 IPR008988 Transcriptional repressor, C-terminal AFULGI_00002310 28a957eb40dc267d83db8fdc7dab2a86 209 Gene3D G3DSA:1.10.10.10 2 124 8.0E-33 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00016910 94d6342282e5eea1d50a10a40a13120f 522 SUPERFAMILY SSF52540 129 485 3.8E-44 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00016910 94d6342282e5eea1d50a10a40a13120f 522 Gene3D G3DSA:3.40.50.300 122 259 5.8E-20 T 01-11-2018 AFULGI_00016910 94d6342282e5eea1d50a10a40a13120f 522 Gene3D G3DSA:3.40.50.300 269 489 5.7E-57 T 01-11-2018 AFULGI_00016910 94d6342282e5eea1d50a10a40a13120f 522 Pfam PF01935 Domain of unknown function DUF87 138 348 1.8E-36 T 01-11-2018 IPR002789 Helicase HerA, central domain AFULGI_00001970 b75d97ca3a8cb0b408b24578993dee39 390 Gene3D G3DSA:3.10.580.10 192 282 8.9E-13 T 01-11-2018 AFULGI_00001970 b75d97ca3a8cb0b408b24578993dee39 390 SUPERFAMILY SSF54631 126 266 2.27E-30 T 01-11-2018 AFULGI_00001970 b75d97ca3a8cb0b408b24578993dee39 390 SUPERFAMILY SSF54631 5 131 4.67E-11 T 01-11-2018 AFULGI_00001970 b75d97ca3a8cb0b408b24578993dee39 390 SUPERFAMILY SSF69754 275 385 8.37E-12 T 01-11-2018 IPR036567 Ribosome hibernation promotion factor-like AFULGI_00001970 b75d97ca3a8cb0b408b24578993dee39 390 PIRSF PIRSF036983 2 390 2.5E-129 T 01-11-2018 IPR014651 Uncharacterised conserved protein, 2xCBS, MJ1404 type AFULGI_00001970 b75d97ca3a8cb0b408b24578993dee39 390 Gene3D G3DSA:3.10.580.10 2 82 1.2E-5 T 01-11-2018 AFULGI_00001970 b75d97ca3a8cb0b408b24578993dee39 390 SMART SM00116 13 63 8.3 T 01-11-2018 IPR000644 CBS domain AFULGI_00001970 b75d97ca3a8cb0b408b24578993dee39 390 SMART SM00116 141 189 4.2E-9 T 01-11-2018 IPR000644 CBS domain AFULGI_00001970 b75d97ca3a8cb0b408b24578993dee39 390 SMART SM00116 219 266 1.5E-4 T 01-11-2018 IPR000644 CBS domain AFULGI_00001970 b75d97ca3a8cb0b408b24578993dee39 390 Pfam PF00571 CBS domain 134 187 2.5E-11 T 01-11-2018 IPR000644 CBS domain AFULGI_00001970 b75d97ca3a8cb0b408b24578993dee39 390 Pfam PF00571 CBS domain 212 266 6.0E-11 T 01-11-2018 IPR000644 CBS domain AFULGI_00001970 b75d97ca3a8cb0b408b24578993dee39 390 Pfam PF00571 CBS domain 7 60 3.8E-5 T 01-11-2018 IPR000644 CBS domain AFULGI_00001970 b75d97ca3a8cb0b408b24578993dee39 390 Gene3D G3DSA:3.10.580.10 84 189 1.8E-20 T 01-11-2018 AFULGI_00024760 5f1da479b98a090417f9ee869a2b6ae8 412 Pfam PF04055 Radical SAM superfamily 58 211 3.5E-19 T 01-11-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFULGI_00024760 5f1da479b98a090417f9ee869a2b6ae8 412 SUPERFAMILY SSF102114 53 357 1.96E-47 T 01-11-2018 AFULGI_00024760 5f1da479b98a090417f9ee869a2b6ae8 412 PIRSF PIRSF037420 42 388 6.8E-32 T 01-11-2018 IPR017200 Coenzyme PQQ synthesis protein E AFULGI_00024760 5f1da479b98a090417f9ee869a2b6ae8 412 SMART SM00729 54 247 0.0038 T 01-11-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 AFULGI_00024760 5f1da479b98a090417f9ee869a2b6ae8 412 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 287 375 1.3E-12 T 01-11-2018 IPR023885 4Fe4S-binding SPASM domain AFULGI_00024760 5f1da479b98a090417f9ee869a2b6ae8 412 TIGRFAM TIGR04163 rSAM_cobopep: peptide-modifying radical SAM enzyme CbpB 2 398 2.2E-188 T 01-11-2018 IPR026423 Peptide-modifying radical SAM enzyme CbpB AFULGI_00024760 5f1da479b98a090417f9ee869a2b6ae8 412 Pfam PF13353 4Fe-4S single cluster domain 62 119 1.1E-4 T 01-11-2018 AFULGI_00024760 5f1da479b98a090417f9ee869a2b6ae8 412 Gene3D G3DSA:3.20.20.70 52 391 1.6E-59 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFULGI_00011330 b92109d059fc4cb8f747fd02221d70d0 270 PRINTS PR00996 Glutamate methyltransferase family signature 137 153 3.5E-40 T 01-11-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 AFULGI_00011330 b92109d059fc4cb8f747fd02221d70d0 270 PRINTS PR00996 Glutamate methyltransferase family signature 62 74 3.5E-40 T 01-11-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 AFULGI_00011330 b92109d059fc4cb8f747fd02221d70d0 270 PRINTS PR00996 Glutamate methyltransferase family signature 204 218 3.5E-40 T 01-11-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 AFULGI_00011330 b92109d059fc4cb8f747fd02221d70d0 270 PRINTS PR00996 Glutamate methyltransferase family signature 223 246 3.5E-40 T 01-11-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 AFULGI_00011330 b92109d059fc4cb8f747fd02221d70d0 270 PRINTS PR00996 Glutamate methyltransferase family signature 24 37 3.5E-40 T 01-11-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 AFULGI_00011330 b92109d059fc4cb8f747fd02221d70d0 270 PRINTS PR00996 Glutamate methyltransferase family signature 104 124 3.5E-40 T 01-11-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 AFULGI_00011330 b92109d059fc4cb8f747fd02221d70d0 270 Gene3D G3DSA:1.10.155.10 1 67 1.3E-12 T 01-11-2018 IPR036804 Chemotaxis receptor methyltransferase CheR, N-terminal domain superfamily AFULGI_00011330 b92109d059fc4cb8f747fd02221d70d0 270 SMART SM00138 2 265 4.2E-139 T 01-11-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 AFULGI_00011330 b92109d059fc4cb8f747fd02221d70d0 270 Gene3D G3DSA:3.40.50.150 68 267 1.2E-63 T 01-11-2018 AFULGI_00011330 b92109d059fc4cb8f747fd02221d70d0 270 SUPERFAMILY SSF53335 69 248 2.34E-47 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFULGI_00011330 b92109d059fc4cb8f747fd02221d70d0 270 Pfam PF03705 CheR methyltransferase, all-alpha domain 5 54 2.0E-14 T 01-11-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal AFULGI_00011330 b92109d059fc4cb8f747fd02221d70d0 270 Pfam PF01739 CheR methyltransferase, SAM binding domain 69 262 5.5E-67 T 01-11-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal AFULGI_00011330 b92109d059fc4cb8f747fd02221d70d0 270 SUPERFAMILY SSF47757 3 68 2.48E-15 T 01-11-2018 AFULGI_00011330 b92109d059fc4cb8f747fd02221d70d0 270 PIRSF PIRSF000410 2 268 2.4E-80 T 01-11-2018 IPR026024 Chemotaxis protein methyltransferase CheR AFULGI_00026910 08d22c7458badbca148fd6739d421804 282 Gene3D G3DSA:3.30.200.20 91 184 1.6E-30 T 01-11-2018 AFULGI_00026910 08d22c7458badbca148fd6739d421804 282 Pfam PF01163 RIO1 family 106 272 7.4E-46 T 01-11-2018 AFULGI_00026910 08d22c7458badbca148fd6739d421804 282 ProSitePatterns PS00109 Tyrosine protein kinases specific active-site signature. 214 226 - T 01-11-2018 IPR008266 Tyrosine-protein kinase, active site GO:0004672|GO:0006468 AFULGI_00026910 08d22c7458badbca148fd6739d421804 282 Gene3D G3DSA:1.10.10.10 1 90 5.4E-43 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00026910 08d22c7458badbca148fd6739d421804 282 Pfam PF09202 Rio2, N-terminal 10 86 1.4E-8 T 01-11-2018 IPR015285 RIO2 kinase winged helix domain, N-terminal GO:0004674|GO:0005524|GO:0006468 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 AFULGI_00026910 08d22c7458badbca148fd6739d421804 282 Gene3D G3DSA:1.10.510.10 185 282 5.1E-29 T 01-11-2018 AFULGI_00026910 08d22c7458badbca148fd6739d421804 282 SMART SM00090 49 281 8.0E-94 T 01-11-2018 IPR000687 RIO kinase GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 AFULGI_00026910 08d22c7458badbca148fd6739d421804 282 SUPERFAMILY SSF46785 2 89 5.58E-22 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00026910 08d22c7458badbca148fd6739d421804 282 SUPERFAMILY SSF56112 94 277 4.32E-34 T 01-11-2018 IPR011009 Protein kinase-like domain superfamily AFULGI_00010770 147845b8bd3038e8c6500d165b6f9bd5 238 TIGRFAM TIGR00007 TIGR00007: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase 4 230 5.1E-79 T 01-11-2018 IPR006063 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase HisA GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 AFULGI_00010770 147845b8bd3038e8c6500d165b6f9bd5 238 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 3 233 32.078 T 01-11-2018 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 AFULGI_00010770 147845b8bd3038e8c6500d165b6f9bd5 238 Pfam PF00977 Histidine biosynthesis protein 3 225 1.3E-65 T 01-11-2018 IPR006062 Histidine biosynthesis GO:0000105 AFULGI_00010770 147845b8bd3038e8c6500d165b6f9bd5 238 SUPERFAMILY SSF51366 2 232 2.42E-62 T 01-11-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 AFULGI_00010770 147845b8bd3038e8c6500d165b6f9bd5 238 Gene3D G3DSA:3.20.20.70 1 236 6.2E-68 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFULGI_00017970 4f1b205e031227811c12e18ae55a641d 271 Pfam PF00432 Prenyltransferase and squalene oxidase repeat 5 47 7.5E-5 T 01-11-2018 IPR001330 PFTB repeat GO:0003824 AFULGI_00017970 4f1b205e031227811c12e18ae55a641d 271 Pfam PF00432 Prenyltransferase and squalene oxidase repeat 231 265 0.047 T 01-11-2018 IPR001330 PFTB repeat GO:0003824 AFULGI_00017970 4f1b205e031227811c12e18ae55a641d 271 Pfam PF00432 Prenyltransferase and squalene oxidase repeat 194 221 1.6 T 01-11-2018 IPR001330 PFTB repeat GO:0003824 AFULGI_00017970 4f1b205e031227811c12e18ae55a641d 271 Gene3D G3DSA:1.50.10.20 1 66 4.0E-7 T 01-11-2018 AFULGI_00017970 4f1b205e031227811c12e18ae55a641d 271 PIRSF PIRSF016175 1 271 3.4E-123 T 01-11-2018 IPR016648 Uncharacterised conserved protein UCP016175, prenyltransferase beta-subunit-related AFULGI_00017970 4f1b205e031227811c12e18ae55a641d 271 Gene3D G3DSA:1.50.10.20 67 269 5.3E-10 T 01-11-2018 AFULGI_00017970 4f1b205e031227811c12e18ae55a641d 271 SUPERFAMILY SSF48239 3 225 7.39E-21 T 01-11-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid AFULGI_00001090 383fe4a49e062fda18914ef7c8d2d2e9 253 Hamap MF_01121 NAD-dependent protein deacylase [cobB]. 16 248 60.923 T 01-11-2018 IPR027546 Sirtuin, class III GO:0036054|GO:0036055|GO:0070403 Reactome: R-HSA-2151201 AFULGI_00001090 383fe4a49e062fda18914ef7c8d2d2e9 253 Hamap MF_01968 NAD-dependent protein deacetylase [cobB]. 7 243 58.332 T 01-11-2018 IPR028628 Sirtuin, class U GO:0034979|GO:0051287 AFULGI_00001090 383fe4a49e062fda18914ef7c8d2d2e9 253 Gene3D G3DSA:3.30.1600.10 32 168 1.3E-89 T 01-11-2018 IPR026591 Sirtuin, catalytic core small domain superfamily AFULGI_00001090 383fe4a49e062fda18914ef7c8d2d2e9 253 Gene3D G3DSA:3.40.50.1220 14 242 1.3E-89 T 01-11-2018 AFULGI_00001090 383fe4a49e062fda18914ef7c8d2d2e9 253 SUPERFAMILY SSF52467 2 246 1.05E-90 T 01-11-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily AFULGI_00001090 383fe4a49e062fda18914ef7c8d2d2e9 253 Pfam PF02146 Sir2 family 23 198 1.6E-59 T 01-11-2018 IPR003000 Sirtuin family GO:0070403 AFULGI_00019410 bd856651bdd57c419288197cef6442b2 209 Gene3D G3DSA:1.10.1670.10 20 201 2.1E-63 T 01-11-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 AFULGI_00019410 bd856651bdd57c419288197cef6442b2 209 PIRSF PIRSF001435 7 208 2.4E-47 T 01-11-2018 AFULGI_00019410 bd856651bdd57c419288197cef6442b2 209 SMART SM00478 40 186 2.0E-67 T 01-11-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 AFULGI_00019410 bd856651bdd57c419288197cef6442b2 209 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 36 168 3.7E-28 T 01-11-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 AFULGI_00019410 bd856651bdd57c419288197cef6442b2 209 Pfam PF00633 Helix-hairpin-helix motif 102 130 4.2E-8 T 01-11-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 AFULGI_00019410 bd856651bdd57c419288197cef6442b2 209 SMART SM00525 187 206 2.6E-4 T 01-11-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 AFULGI_00019410 bd856651bdd57c419288197cef6442b2 209 SUPERFAMILY SSF48150 27 203 8.64E-62 T 01-11-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 AFULGI_00019410 bd856651bdd57c419288197cef6442b2 209 Gene3D G3DSA:1.10.340.30 23 133 2.1E-63 T 01-11-2018 AFULGI_00019410 bd856651bdd57c419288197cef6442b2 209 Hamap MF_00942 Endonuclease III [nth]. 4 209 32.445 T 01-11-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 AFULGI_00019410 bd856651bdd57c419288197cef6442b2 209 SMART SM00278 111 130 0.0091 T 01-11-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 AFULGI_00007330 8663436fbd01d4b66bd71bacc2c426f2 96 Gene3D G3DSA:1.10.10.10 20 96 5.5E-12 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00007330 8663436fbd01d4b66bd71bacc2c426f2 96 Pfam PF01022 Bacterial regulatory protein, arsR family 26 67 2.5E-11 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFULGI_00007330 8663436fbd01d4b66bd71bacc2c426f2 96 SUPERFAMILY SSF46785 27 93 1.48E-13 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00008830 595274936e48cf325f55ca45effb4533 419 PRINTS PR01181 Diaminopimelate decarboxylase signature 71 88 6.2E-26 T 01-11-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AFULGI_00008830 595274936e48cf325f55ca45effb4533 419 PRINTS PR01181 Diaminopimelate decarboxylase signature 159 168 6.2E-26 T 01-11-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AFULGI_00008830 595274936e48cf325f55ca45effb4533 419 PRINTS PR01181 Diaminopimelate decarboxylase signature 298 316 6.2E-26 T 01-11-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AFULGI_00008830 595274936e48cf325f55ca45effb4533 419 PRINTS PR01181 Diaminopimelate decarboxylase signature 380 402 6.2E-26 T 01-11-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AFULGI_00008830 595274936e48cf325f55ca45effb4533 419 SUPERFAMILY SSF51419 24 282 3.34E-75 T 01-11-2018 IPR029066 PLP-binding barrel AFULGI_00008830 595274936e48cf325f55ca45effb4533 419 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 4 412 2.2E-169 T 01-11-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AFULGI_00008830 595274936e48cf325f55ca45effb4533 419 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 53 71 - T 01-11-2018 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site AFULGI_00008830 595274936e48cf325f55ca45effb4533 419 Gene3D G3DSA:2.40.37.10 11 409 1.8E-149 T 01-11-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 AFULGI_00008830 595274936e48cf325f55ca45effb4533 419 Gene3D G3DSA:3.20.20.10 32 276 1.8E-149 T 01-11-2018 IPR029066 PLP-binding barrel AFULGI_00008830 595274936e48cf325f55ca45effb4533 419 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 53 71 5.9E-23 T 01-11-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 AFULGI_00008830 595274936e48cf325f55ca45effb4533 419 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 185 198 5.9E-23 T 01-11-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 AFULGI_00008830 595274936e48cf325f55ca45effb4533 419 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 73 85 5.9E-23 T 01-11-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 AFULGI_00008830 595274936e48cf325f55ca45effb4533 419 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 370 383 5.9E-23 T 01-11-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 AFULGI_00008830 595274936e48cf325f55ca45effb4533 419 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 271 290 5.9E-23 T 01-11-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 AFULGI_00008830 595274936e48cf325f55ca45effb4533 419 SUPERFAMILY SSF50621 265 415 3.98E-55 T 01-11-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 AFULGI_00008830 595274936e48cf325f55ca45effb4533 419 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 282 370 2.5E-27 T 01-11-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 AFULGI_00008830 595274936e48cf325f55ca45effb4533 419 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 223 236 - T 01-11-2018 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site AFULGI_00008830 595274936e48cf325f55ca45effb4533 419 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 34 281 3.4E-55 T 01-11-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 AFULGI_00008830 595274936e48cf325f55ca45effb4533 419 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 13 413 41.889 T 01-11-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AFULGI_00024460 7b55f70295eba394434083ac38c5cf5f 273 Pfam PF09810 Exonuclease V - a 5' deoxyribonuclease 194 272 1.3E-10 T 01-11-2018 IPR019190 Exonuclease V GO:0045145 AFULGI_00024460 7b55f70295eba394434083ac38c5cf5f 273 Pfam PF09810 Exonuclease V - a 5' deoxyribonuclease 3 118 5.3E-8 T 01-11-2018 IPR019190 Exonuclease V GO:0045145 AFULGI_00019650 d6b96b87fe854de162f354c315cf052e 508 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 203 217 2.6E-10 T 01-11-2018 AFULGI_00019650 d6b96b87fe854de162f354c315cf052e 508 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 282 294 2.6E-10 T 01-11-2018 AFULGI_00019650 d6b96b87fe854de162f354c315cf052e 508 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 179 195 2.6E-10 T 01-11-2018 AFULGI_00019650 d6b96b87fe854de162f354c315cf052e 508 Pfam PF12161 HsdM N-terminal domain 21 146 6.8E-14 T 01-11-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain AFULGI_00019650 d6b96b87fe854de162f354c315cf052e 508 SUPERFAMILY SSF53335 15 506 1.15E-113 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFULGI_00019650 d6b96b87fe854de162f354c315cf052e 508 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 285 291 - T 01-11-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 AFULGI_00019650 d6b96b87fe854de162f354c315cf052e 508 Gene3D G3DSA:1.20.1260.30 7 173 4.4E-15 T 01-11-2018 IPR038333 N6 adenine-specific DNA methyltransferase, N-terminal domain superfamily AFULGI_00019650 d6b96b87fe854de162f354c315cf052e 508 Gene3D G3DSA:3.40.50.150 177 464 1.0E-79 T 01-11-2018 AFULGI_00019650 d6b96b87fe854de162f354c315cf052e 508 Pfam PF02384 N-6 DNA Methylase 157 471 5.4E-107 T 01-11-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 AFULGI_00002440 292af11ecfc279b310a6a24a79ae94a5 373 SUPERFAMILY SSF56059 124 373 7.42E-52 T 01-11-2018 AFULGI_00002440 292af11ecfc279b310a6a24a79ae94a5 373 Gene3D G3DSA:3.30.1490.20 138 203 1.1E-66 T 01-11-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 AFULGI_00002440 292af11ecfc279b310a6a24a79ae94a5 373 Pfam PF06849 Protein of unknown function (DUF1246) 15 141 1.7E-44 T 01-11-2018 IPR010672 IMP biosynthesis enzyme PurP, N-terminal GO:0000287|GO:0005524|GO:0006188|GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 AFULGI_00002440 292af11ecfc279b310a6a24a79ae94a5 373 Pfam PF06973 Domain of unknown function (DUF1297) 174 373 4.2E-63 T 01-11-2018 IPR009720 IMP biosynthesis enzyme PurP, C-terminal GO:0000287|GO:0005524|GO:0006188|GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 AFULGI_00002440 292af11ecfc279b310a6a24a79ae94a5 373 PIRSF PIRSF004602 1 373 7.0E-136 T 01-11-2018 IPR023656 IMP biosynthesis enzyme PurP GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 AFULGI_00002440 292af11ecfc279b310a6a24a79ae94a5 373 Gene3D G3DSA:3.30.470.20 108 372 1.1E-66 T 01-11-2018 AFULGI_00002440 292af11ecfc279b310a6a24a79ae94a5 373 Gene3D G3DSA:3.40.50.20 2 107 2.0E-34 T 01-11-2018 AFULGI_00002440 292af11ecfc279b310a6a24a79ae94a5 373 SUPERFAMILY SSF52440 9 119 6.14E-38 T 01-11-2018 IPR016185 Pre-ATP-grasp domain superfamily AFULGI_00026290 7b71fb97d44adc06b1cda664c41df797 457 Gene3D G3DSA:3.90.1300.10 2 454 3.7E-173 T 01-11-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AFULGI_00026290 7b71fb97d44adc06b1cda664c41df797 457 Pfam PF01425 Amidase 18 443 1.1E-158 T 01-11-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AFULGI_00026290 7b71fb97d44adc06b1cda664c41df797 457 ProSitePatterns PS00571 Amidases signature. 139 170 - T 01-11-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 AFULGI_00026290 7b71fb97d44adc06b1cda664c41df797 457 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 6 454 91.126 T 01-11-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AFULGI_00026290 7b71fb97d44adc06b1cda664c41df797 457 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 4 453 1.3E-198 T 01-11-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AFULGI_00026290 7b71fb97d44adc06b1cda664c41df797 457 SUPERFAMILY SSF75304 15 452 2.88E-147 T 01-11-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AFULGI_00020760 803427bd9ab2b6a0db78903bd141a3bb 268 SUPERFAMILY SSF56300 2 232 2.76E-44 T 01-11-2018 AFULGI_00020760 803427bd9ab2b6a0db78903bd141a3bb 268 Gene3D G3DSA:3.60.21.10 1 249 9.1E-47 T 01-11-2018 IPR029052 Metallo-dependent phosphatase-like AFULGI_00020760 803427bd9ab2b6a0db78903bd141a3bb 268 PRINTS PR00114 Serine/threonine phosphatase family signature 51 78 3.9E-10 T 01-11-2018 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFULGI_00020760 803427bd9ab2b6a0db78903bd141a3bb 268 PRINTS PR00114 Serine/threonine phosphatase family signature 118 144 3.9E-10 T 01-11-2018 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFULGI_00020760 803427bd9ab2b6a0db78903bd141a3bb 268 PRINTS PR00114 Serine/threonine phosphatase family signature 147 174 3.9E-10 T 01-11-2018 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFULGI_00020760 803427bd9ab2b6a0db78903bd141a3bb 268 Pfam PF00149 Calcineurin-like phosphoesterase 27 215 5.4E-20 T 01-11-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 AFULGI_00020760 803427bd9ab2b6a0db78903bd141a3bb 268 SMART SM00156 1 255 5.1E-13 T 01-11-2018 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFULGI_00026860 9d10512b8b78cea5f1dbd58a96c2635b 932 SUPERFAMILY SSF52374 3 676 1.1E-102 T 01-11-2018 AFULGI_00026860 9d10512b8b78cea5f1dbd58a96c2635b 932 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 392 669 2.3E-19 T 01-11-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFULGI_00026860 9d10512b8b78cea5f1dbd58a96c2635b 932 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 10 319 8.3E-45 T 01-11-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFULGI_00026860 9d10512b8b78cea5f1dbd58a96c2635b 932 Gene3D G3DSA:1.10.10.720 832 883 9.4E-32 T 01-11-2018 AFULGI_00026860 9d10512b8b78cea5f1dbd58a96c2635b 932 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 38 49 - T 01-11-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFULGI_00026860 9d10512b8b78cea5f1dbd58a96c2635b 932 SUPERFAMILY SSF47323 679 869 1.78E-33 T 01-11-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFULGI_00026860 9d10512b8b78cea5f1dbd58a96c2635b 932 Hamap MF_00049_A Leucine--tRNA ligase [leuS]. 4 932 18.054 T 01-11-2018 IPR020791 Leucine-tRNA ligase, archaeal GO:0000166|GO:0004823|GO:0005524|GO:0005737|GO:0006429 KEGG: 00970+6.1.1.4 AFULGI_00026860 9d10512b8b78cea5f1dbd58a96c2635b 932 Gene3D G3DSA:1.10.730.10 670 777 3.7E-24 T 01-11-2018 AFULGI_00026860 9d10512b8b78cea5f1dbd58a96c2635b 932 TIGRFAM TIGR00395 leuS_arch: leucine--tRNA ligase 6 931 0.0 T 01-11-2018 IPR004493 Leucyl-tRNA synthetase, class Ia, archaeal/eukaryotic cytosolic GO:0000166|GO:0004823|GO:0005524|GO:0005737|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 AFULGI_00026860 9d10512b8b78cea5f1dbd58a96c2635b 932 Gene3D G3DSA:3.40.50.620 7 668 8.0E-285 T 01-11-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFULGI_00026860 9d10512b8b78cea5f1dbd58a96c2635b 932 Pfam PF08264 Anticodon-binding domain of tRNA 703 819 6.8E-23 T 01-11-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 AFULGI_00026860 9d10512b8b78cea5f1dbd58a96c2635b 932 Gene3D G3DSA:3.90.740.10 198 438 8.0E-285 T 01-11-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 AFULGI_00026860 9d10512b8b78cea5f1dbd58a96c2635b 932 Gene3D G3DSA:3.30.2320.20 804 931 9.4E-32 T 01-11-2018 AFULGI_00026860 9d10512b8b78cea5f1dbd58a96c2635b 932 SUPERFAMILY SSF50677 203 430 1.22E-33 T 01-11-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 AFULGI_00025380 1d288d26d2a8dec3991f66b004c4c2c6 692 Pfam PF00270 DEAD/DEAH box helicase 29 187 4.0E-27 T 01-11-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 AFULGI_00025380 1d288d26d2a8dec3991f66b004c4c2c6 692 SUPERFAMILY SSF52540 198 395 2.49E-47 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00025380 1d288d26d2a8dec3991f66b004c4c2c6 692 SUPERFAMILY SSF52540 11 196 1.36E-48 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00025380 1d288d26d2a8dec3991f66b004c4c2c6 692 SMART SM00487 23 208 1.2E-32 T 01-11-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFULGI_00025380 1d288d26d2a8dec3991f66b004c4c2c6 692 Pfam PF00271 Helicase conserved C-terminal domain 285 375 1.2E-9 T 01-11-2018 IPR001650 Helicase, C-terminal AFULGI_00025380 1d288d26d2a8dec3991f66b004c4c2c6 692 SMART SM00490 290 375 4.9E-19 T 01-11-2018 IPR001650 Helicase, C-terminal AFULGI_00025380 1d288d26d2a8dec3991f66b004c4c2c6 692 Gene3D G3DSA:1.10.3380.30 412 629 1.6E-84 T 01-11-2018 AFULGI_00025380 1d288d26d2a8dec3991f66b004c4c2c6 692 Gene3D G3DSA:1.10.150.20 631 686 2.7E-25 T 01-11-2018 AFULGI_00025380 1d288d26d2a8dec3991f66b004c4c2c6 692 SUPERFAMILY SSF46785 406 489 1.99E-19 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00025380 1d288d26d2a8dec3991f66b004c4c2c6 692 Gene3D G3DSA:3.40.50.300 205 400 6.9E-65 T 01-11-2018 AFULGI_00025380 1d288d26d2a8dec3991f66b004c4c2c6 692 Gene3D G3DSA:3.40.50.300 8 204 3.1E-78 T 01-11-2018 AFULGI_00025380 1d288d26d2a8dec3991f66b004c4c2c6 692 Hamap MF_00442 ATP-dependent DNA helicase Hel308 [hel308]. 12 685 29.69 T 01-11-2018 IPR022965 ATP-dependent DNA helicase Hel308 GO:0004386 AFULGI_00025380 1d288d26d2a8dec3991f66b004c4c2c6 692 SUPERFAMILY SSF158702 490 687 9.68E-78 T 01-11-2018 AFULGI_00023320 f9b3f32266169ba6ea14a0f161e4eca4 57 Pfam PF01775 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A 9 55 9.8E-12 T 01-11-2018 IPR023573 Ribosomal protein 50S-L18Ae/60S-L20/60S-L18A GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00023320 f9b3f32266169ba6ea14a0f161e4eca4 57 SUPERFAMILY SSF160374 3 56 1.83E-18 T 01-11-2018 AFULGI_00023320 f9b3f32266169ba6ea14a0f161e4eca4 57 Hamap MF_00273 50S ribosomal protein L18Ae [rpl18a]. 1 55 18.947 T 01-11-2018 IPR028877 50S ribosomal protein L18Ae/60S ribosomal protein L20 and L18a Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00023320 f9b3f32266169ba6ea14a0f161e4eca4 57 Gene3D G3DSA:3.10.20.10 1 55 5.2E-25 T 01-11-2018 AFULGI_00023320 f9b3f32266169ba6ea14a0f161e4eca4 57 ProDom PD010302 RIBOSOMAL LX 50S RIBONUCLEOPROTEIN HL32 DIRECT SEQUENCING LXA LSU 3 54 3.0E-23 T 01-11-2018 IPR002768 50S ribosomal protein L18Ae, archaea GO:0003735|GO:0005840|GO:0006412 AFULGI_00008920 208848a7acfb05a9e8cec649d540d557 311 PIRSF PIRSF000138 1 164 6.4E-31 T 01-11-2018 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 Reactome: R-HSA-9033241 AFULGI_00008920 208848a7acfb05a9e8cec649d540d557 311 PIRSF PIRSF000138 161 311 4.7E-56 T 01-11-2018 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 Reactome: R-HSA-9033241 AFULGI_00008920 208848a7acfb05a9e8cec649d540d557 311 Pfam PF01070 FMN-dependent dehydrogenase 20 157 1.7E-16 T 01-11-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 Reactome: R-HSA-9033241 AFULGI_00008920 208848a7acfb05a9e8cec649d540d557 311 Pfam PF01070 FMN-dependent dehydrogenase 174 309 1.8E-44 T 01-11-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 Reactome: R-HSA-9033241 AFULGI_00008920 208848a7acfb05a9e8cec649d540d557 311 Gene3D G3DSA:3.20.20.70 160 311 2.1E-40 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFULGI_00008920 208848a7acfb05a9e8cec649d540d557 311 Gene3D G3DSA:3.20.20.70 1 159 3.5E-15 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFULGI_00008920 208848a7acfb05a9e8cec649d540d557 311 SUPERFAMILY SSF51395 20 310 9.77E-41 T 01-11-2018 AFULGI_00004460 523b1283ac3617086845f9443a40210d 239 Gene3D G3DSA:3.40.50.620 1 216 1.0E-68 T 01-11-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFULGI_00004460 523b1283ac3617086845f9443a40210d 239 TIGRFAM TIGR00364 TIGR00364: queuosine biosynthesis protein QueC 3 201 2.8E-78 T 01-11-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 AFULGI_00004460 523b1283ac3617086845f9443a40210d 239 PIRSF PIRSF006293 1 221 1.8E-85 T 01-11-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 AFULGI_00004460 523b1283ac3617086845f9443a40210d 239 Pfam PF06508 Queuosine biosynthesis protein QueC 2 207 7.7E-71 T 01-11-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 AFULGI_00004460 523b1283ac3617086845f9443a40210d 239 Hamap MF_01633 7-cyano-7-deazaguanine synthase [queC]. 1 214 50.246 T 01-11-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 AFULGI_00004460 523b1283ac3617086845f9443a40210d 239 SUPERFAMILY SSF52402 1 215 2.12E-59 T 01-11-2018 AFULGI_00012430 fb93f0c74c29b770d8b1ddb6e79a3985 451 Gene3D G3DSA:1.20.1720.10 8 233 5.3E-43 T 01-11-2018 AFULGI_00012430 fb93f0c74c29b770d8b1ddb6e79a3985 451 Gene3D G3DSA:1.20.1250.20 241 447 9.0E-24 T 01-11-2018 AFULGI_00012430 fb93f0c74c29b770d8b1ddb6e79a3985 451 SUPERFAMILY SSF103473 7 447 4.05E-66 T 01-11-2018 IPR036259 MFS transporter superfamily AFULGI_00012430 fb93f0c74c29b770d8b1ddb6e79a3985 451 Pfam PF07690 Major Facilitator Superfamily 14 395 5.0E-53 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFULGI_00012430 fb93f0c74c29b770d8b1ddb6e79a3985 451 PRINTS PR01036 Tetracycline resistance protein TetB signature 288 312 7.6E-7 T 01-11-2018 AFULGI_00012430 fb93f0c74c29b770d8b1ddb6e79a3985 451 PRINTS PR01036 Tetracycline resistance protein TetB signature 218 236 7.6E-7 T 01-11-2018 AFULGI_00012430 fb93f0c74c29b770d8b1ddb6e79a3985 451 PRINTS PR01036 Tetracycline resistance protein TetB signature 131 155 7.6E-7 T 01-11-2018 AFULGI_00012430 fb93f0c74c29b770d8b1ddb6e79a3985 451 PRINTS PR01036 Tetracycline resistance protein TetB signature 70 92 7.6E-7 T 01-11-2018 AFULGI_00010780 f00725ec69991ad5682813bc978ea03a 133 SUPERFAMILY SSF52402 3 130 2.85E-26 T 01-11-2018 AFULGI_00010780 f00725ec69991ad5682813bc978ea03a 133 PRINTS PR01438 Universal stress protein signature 108 130 7.8E-7 T 01-11-2018 IPR006015 Universal stress protein A AFULGI_00010780 f00725ec69991ad5682813bc978ea03a 133 PRINTS PR01438 Universal stress protein signature 90 102 7.8E-7 T 01-11-2018 IPR006015 Universal stress protein A AFULGI_00010780 f00725ec69991ad5682813bc978ea03a 133 Pfam PF00582 Universal stress protein family 3 130 2.1E-25 T 01-11-2018 IPR006016 UspA AFULGI_00010780 f00725ec69991ad5682813bc978ea03a 133 Gene3D G3DSA:3.40.50.620 1 130 1.3E-30 T 01-11-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFULGI_00005440 be9f6d274f31b859a2dc068050b56f73 368 SMART SM00864 44 235 7.9E-107 T 01-11-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 AFULGI_00005440 be9f6d274f31b859a2dc068050b56f73 368 SMART SM00865 237 354 1.5E-50 T 01-11-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-380320 AFULGI_00005440 be9f6d274f31b859a2dc068050b56f73 368 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 45 204 6.2E-45 T 01-11-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 AFULGI_00005440 be9f6d274f31b859a2dc068050b56f73 368 PRINTS PR00423 Cell division protein FtsZ signature 219 241 1.8E-44 T 01-11-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 AFULGI_00005440 be9f6d274f31b859a2dc068050b56f73 368 PRINTS PR00423 Cell division protein FtsZ signature 242 263 1.8E-44 T 01-11-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 AFULGI_00005440 be9f6d274f31b859a2dc068050b56f73 368 PRINTS PR00423 Cell division protein FtsZ signature 157 178 1.8E-44 T 01-11-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 AFULGI_00005440 be9f6d274f31b859a2dc068050b56f73 368 PRINTS PR00423 Cell division protein FtsZ signature 129 149 1.8E-44 T 01-11-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 AFULGI_00005440 be9f6d274f31b859a2dc068050b56f73 368 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 40 363 38.233 T 01-11-2018 IPR000158 Cell division protein FtsZ GO:0005525 AFULGI_00005440 be9f6d274f31b859a2dc068050b56f73 368 Gene3D G3DSA:3.40.50.1440 35 250 6.4E-80 T 01-11-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 AFULGI_00005440 be9f6d274f31b859a2dc068050b56f73 368 ProSitePatterns PS01134 FtsZ protein signature 1. 75 109 - T 01-11-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 AFULGI_00005440 be9f6d274f31b859a2dc068050b56f73 368 Pfam PF12327 FtsZ family, C-terminal domain 252 346 7.3E-39 T 01-11-2018 IPR024757 Cell division protein FtsZ, C-terminal AFULGI_00005440 be9f6d274f31b859a2dc068050b56f73 368 SUPERFAMILY SSF55307 237 352 3.89E-42 T 01-11-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 AFULGI_00005440 be9f6d274f31b859a2dc068050b56f73 368 SUPERFAMILY SSF52490 44 238 7.98E-67 T 01-11-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 AFULGI_00005440 be9f6d274f31b859a2dc068050b56f73 368 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 30 356 1.4E-144 T 01-11-2018 IPR000158 Cell division protein FtsZ GO:0005525 AFULGI_00005440 be9f6d274f31b859a2dc068050b56f73 368 Gene3D G3DSA:3.30.1330.20 255 360 6.2E-36 T 01-11-2018 IPR037103 Tubulin/FtsZ, C-terminal domain superfamily Reactome: R-HSA-380320 AFULGI_00005440 be9f6d274f31b859a2dc068050b56f73 368 ProSitePatterns PS01135 FtsZ protein signature 2. 128 149 - T 01-11-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 AFULGI_00008970 6c4f27de651e86d5cd4e5cb3885be4fc 364 SUPERFAMILY SSF46548 281 362 3.01E-14 T 01-11-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 AFULGI_00008970 6c4f27de651e86d5cd4e5cb3885be4fc 364 TIGRFAM TIGR00273 TIGR00273: iron-sulfur cluster-binding protein 12 358 3.7E-163 T 01-11-2018 IPR004452 4Fe-4S binding protein GO:0019516 AFULGI_00008970 6c4f27de651e86d5cd4e5cb3885be4fc 364 Pfam PF13183 4Fe-4S dicluster domain 284 347 3.3E-10 T 01-11-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFULGI_00008970 6c4f27de651e86d5cd4e5cb3885be4fc 364 SUPERFAMILY SSF100950 54 256 2.18E-24 T 01-11-2018 IPR037171 NagB/RpiA transferase-like AFULGI_00008970 6c4f27de651e86d5cd4e5cb3885be4fc 364 Gene3D G3DSA:3.40.50.10420 109 245 3.7E-7 T 01-11-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily AFULGI_00008970 6c4f27de651e86d5cd4e5cb3885be4fc 364 Pfam PF02589 LUD domain 59 237 4.6E-34 T 01-11-2018 IPR003741 LUD domain AFULGI_00008970 6c4f27de651e86d5cd4e5cb3885be4fc 364 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 286 297 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFULGI_00007010 c241c3e15f30208eb76015fb0c6db2a7 205 Gene3D G3DSA:3.30.420.10 1 155 1.1E-61 T 01-11-2018 IPR036397 Ribonuclease H superfamily GO:0003676 AFULGI_00007010 c241c3e15f30208eb76015fb0c6db2a7 205 SUPERFAMILY SSF53098 2 198 3.19E-51 T 01-11-2018 IPR012337 Ribonuclease H-like superfamily AFULGI_00007010 c241c3e15f30208eb76015fb0c6db2a7 205 TIGRFAM TIGR00729 TIGR00729: ribonuclease HII 3 199 3.6E-81 T 01-11-2018 IPR004649 Ribonuclease H2, subunit A GO:0004523|GO:0016070 AFULGI_00007010 c241c3e15f30208eb76015fb0c6db2a7 205 Pfam PF01351 Ribonuclease HII 3 194 8.5E-63 T 01-11-2018 IPR024567 Ribonuclease HII/HIII domain AFULGI_00007010 c241c3e15f30208eb76015fb0c6db2a7 205 Hamap MF_00052_A Ribonuclease HII [rnhB]. 1 199 34.193 T 01-11-2018 IPR020787 Ribonuclease HII, archaea GO:0004523|GO:0005737|GO:0006401|GO:0030145 AFULGI_00007010 c241c3e15f30208eb76015fb0c6db2a7 205 Gene3D G3DSA:1.10.10.460 156 205 6.9E-25 T 01-11-2018 IPR023160 Ribonuclease HII, helix-loop-helix cap domain superfamily GO:0004523 AFULGI_00010870 bb0068bececf2fecf2285c266fbc190d 337 Pfam PF14520 Helix-hairpin-helix domain 13 67 5.0E-13 T 01-11-2018 AFULGI_00010870 bb0068bececf2fecf2285c266fbc190d 337 Gene3D G3DSA:3.40.50.300 73 337 2.7E-81 T 01-11-2018 AFULGI_00010870 bb0068bececf2fecf2285c266fbc190d 337 TIGRFAM TIGR02236 recomb_radA: DNA repair and recombination protein RadA 13 326 1.3E-169 T 01-11-2018 IPR011938 DNA recombination/repair protein RadA GO:0003684|GO:0005524|GO:0006281|GO:0006310|GO:0008094 AFULGI_00010870 bb0068bececf2fecf2285c266fbc190d 337 PIRSF PIRSF005856 2 330 1.0E-133 T 01-11-2018 IPR016467 DNA recombination and repair protein, RecA-like Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579 AFULGI_00010870 bb0068bececf2fecf2285c266fbc190d 337 SMART SM00382 107 296 4.6E-12 T 01-11-2018 IPR003593 AAA+ ATPase domain AFULGI_00010870 bb0068bececf2fecf2285c266fbc190d 337 Hamap MF_00348 DNA repair and recombination protein RadA [radA]. 11 326 80.476 T 01-11-2018 IPR011938 DNA recombination/repair protein RadA GO:0003684|GO:0005524|GO:0006281|GO:0006310|GO:0008094 AFULGI_00010870 bb0068bececf2fecf2285c266fbc190d 337 SUPERFAMILY SSF47794 6 70 1.32E-14 T 01-11-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 AFULGI_00010870 bb0068bececf2fecf2285c266fbc190d 337 SUPERFAMILY SSF52540 87 326 2.36E-57 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00010870 bb0068bececf2fecf2285c266fbc190d 337 SMART SM00278 45 64 2400.0 T 01-11-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 AFULGI_00010870 bb0068bececf2fecf2285c266fbc190d 337 SMART SM00278 12 31 0.0046 T 01-11-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 AFULGI_00010870 bb0068bececf2fecf2285c266fbc190d 337 Gene3D G3DSA:1.10.150.20 1 71 1.5E-23 T 01-11-2018 AFULGI_00010870 bb0068bececf2fecf2285c266fbc190d 337 Pfam PF08423 Rad51 73 327 7.2E-92 T 01-11-2018 IPR013632 DNA recombination and repair protein Rad51-like, C-terminal Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579 AFULGI_00000660 569ca95b521bb804382fa3660359cd12 241 Gene3D G3DSA:3.30.70.1900 124 241 4.7E-38 T 01-11-2018 AFULGI_00000660 569ca95b521bb804382fa3660359cd12 241 Pfam PF01881 CRISPR associated protein Cas6 96 240 9.5E-39 T 01-11-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 AFULGI_00000660 569ca95b521bb804382fa3660359cd12 241 Gene3D G3DSA:3.30.70.1890 1 123 1.1E-31 T 01-11-2018 AFULGI_00000660 569ca95b521bb804382fa3660359cd12 241 TIGRFAM TIGR01877 cas_cas6: CRISPR-associated endoribonuclease Cas6 42 239 6.5E-53 T 01-11-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 AFULGI_00000660 569ca95b521bb804382fa3660359cd12 241 PIRSF PIRSF005054 1 241 5.0E-68 T 01-11-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 AFULGI_00016050 669d2e51b3db8c1cf017246208ee6c68 86 SUPERFAMILY SSF54786 10 84 5.49E-16 T 01-11-2018 AFULGI_00016050 669d2e51b3db8c1cf017246208ee6c68 86 Gene3D G3DSA:3.30.920.30 11 84 1.1E-18 T 01-11-2018 IPR038570 HicA superfamily AFULGI_00016050 669d2e51b3db8c1cf017246208ee6c68 86 Pfam PF07927 HicA toxin of bacterial toxin-antitoxin, 16 76 2.9E-16 T 01-11-2018 IPR012933 HicA mRNA interferase family GO:0003729 AFULGI_00002730 dbb438ebc5104340cdf45fb53e921575 71 SUPERFAMILY SSF50249 11 71 4.51E-17 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold AFULGI_00002730 dbb438ebc5104340cdf45fb53e921575 71 Gene3D G3DSA:2.40.50.140 5 71 7.3E-25 T 01-11-2018 AFULGI_00002730 dbb438ebc5104340cdf45fb53e921575 71 Pfam PF01938 TRAM domain 14 70 2.5E-16 T 01-11-2018 IPR002792 TRAM domain AFULGI_00001130 7f8170e7104e0836faa928753c6bc7c6 226 Gene3D G3DSA:3.40.50.10090 1 102 2.2E-7 T 01-11-2018 AFULGI_00001130 7f8170e7104e0836faa928753c6bc7c6 226 SUPERFAMILY SSF69618 1 222 8.63E-41 T 01-11-2018 IPR036108 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase superfamily GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AFULGI_00001130 7f8170e7104e0836faa928753c6bc7c6 226 Gene3D G3DSA:3.40.50.10090 103 225 3.5E-18 T 01-11-2018 AFULGI_00001130 7f8170e7104e0836faa928753c6bc7c6 226 Pfam PF02602 Uroporphyrinogen-III synthase HemD 14 218 6.1E-29 T 01-11-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AFULGI_00025810 29ed31369873867272fce51306795381 133 PIRSF PIRSF002131 1 133 6.4E-35 T 01-11-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 AFULGI_00025810 29ed31369873867272fce51306795381 133 Gene3D G3DSA:3.30.420.80 1 133 6.2E-62 T 01-11-2018 IPR036967 Ribosomal protein S11 superfamily GO:0003735|GO:0005840|GO:0006412 AFULGI_00025810 29ed31369873867272fce51306795381 133 TIGRFAM TIGR03628 arch_S11P: ribosomal protein uS11 9 125 9.2E-66 T 01-11-2018 IPR019961 Ribosomal protein S11, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFULGI_00025810 29ed31369873867272fce51306795381 133 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 4 130 23.605 T 01-11-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 AFULGI_00025810 29ed31369873867272fce51306795381 133 Pfam PF00411 Ribosomal protein S11 11 129 6.5E-46 T 01-11-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 AFULGI_00025810 29ed31369873867272fce51306795381 133 SUPERFAMILY SSF53137 9 131 1.31E-38 T 01-11-2018 AFULGI_00025810 29ed31369873867272fce51306795381 133 ProSitePatterns PS00054 Ribosomal protein S11 signature. 98 120 - T 01-11-2018 IPR018102 Ribosomal S11, conserved site AFULGI_00002760 81d87efdb30732a7e0be40a368ff159e 113 ProDom PD020367 UPF0212 RRNAC1165 RRNAC0441 AF0282 VNG1264C MJ0068 PYRAB08340 PH1312 MA1372 TK1194 1 101 2.0E-53 T 01-11-2018 IPR007564 Uncharacterised protein family UPF0212 AFULGI_00002760 81d87efdb30732a7e0be40a368ff159e 113 Hamap MF_01223 UPF0212 protein . 1 111 33.955 T 01-11-2018 IPR007564 Uncharacterised protein family UPF0212 AFULGI_00002760 81d87efdb30732a7e0be40a368ff159e 113 PIRSF PIRSF016934 1 113 4.6E-55 T 01-11-2018 IPR007564 Uncharacterised protein family UPF0212 AFULGI_00002760 81d87efdb30732a7e0be40a368ff159e 113 Pfam PF04475 Protein of unknown function (DUF555) 3 103 1.4E-46 T 01-11-2018 IPR007564 Uncharacterised protein family UPF0212 AFULGI_00019240 469863bf1b6d63f8b08a704dc48d1061 127 Gene3D G3DSA:3.40.30.10 21 117 6.7E-14 T 01-11-2018 AFULGI_00019240 469863bf1b6d63f8b08a704dc48d1061 127 Pfam PF13899 Thioredoxin-like 30 91 3.4E-10 T 01-11-2018 AFULGI_00019240 469863bf1b6d63f8b08a704dc48d1061 127 SUPERFAMILY SSF52833 6 101 7.08E-17 T 01-11-2018 IPR036249 Thioredoxin-like superfamily AFULGI_00013550 df7f9dd68223b36c97695d707fb622fb 320 SUPERFAMILY SSF53335 132 286 6.75E-29 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFULGI_00013550 df7f9dd68223b36c97695d707fb622fb 320 SUPERFAMILY SSF143437 48 134 6.28E-7 T 01-11-2018 AFULGI_00013550 df7f9dd68223b36c97695d707fb622fb 320 TIGRFAM TIGR01177 TIGR01177: putative methyltransferase, TIGR01177 family 3 317 9.3E-123 T 01-11-2018 IPR005885 tRNA guanine(10)-N2-dimethyltransferase GO:0004809|GO:0030488 AFULGI_00013550 df7f9dd68223b36c97695d707fb622fb 320 Pfam PF02926 THUMP domain 17 134 4.9E-9 T 01-11-2018 IPR004114 THUMP domain GO:0003723 AFULGI_00013550 df7f9dd68223b36c97695d707fb622fb 320 Gene3D G3DSA:3.40.50.150 149 320 1.4E-34 T 01-11-2018 AFULGI_00013550 df7f9dd68223b36c97695d707fb622fb 320 Pfam PF01170 Putative RNA methylase family UPF0020 149 314 1.1E-45 T 01-11-2018 IPR000241 Putative RNA methylase domain AFULGI_00013550 df7f9dd68223b36c97695d707fb622fb 320 ProSitePatterns PS01261 Uncharacterized protein family UPF0020 signature. 182 193 - T 01-11-2018 IPR000241 Putative RNA methylase domain AFULGI_00008650 935298880881861cf503613642d2bcc5 313 Pfam PF04087 Domain of unknown function (DUF389) 128 264 1.3E-29 T 01-11-2018 IPR005240 Protein of unknown function DUF389 AFULGI_00008650 935298880881861cf503613642d2bcc5 313 TIGRFAM TIGR00271 TIGR00271: uncharacterized hydrophobic domain 95 270 1.6E-54 T 01-11-2018 AFULGI_00008650 935298880881861cf503613642d2bcc5 313 TIGRFAM TIGR00341 TIGR00341: TIGR00341 family protein 1 312 6.8E-140 T 01-11-2018 AFULGI_00013330 35c0b0852157b98de04dee3b519dc793 103 ProSitePatterns PS01030 RNA polymerases M / 15 Kd subunits signature. 3 23 - T 01-11-2018 IPR019761 DNA-directed RNA polymerase M, 15kDa subunit, conserved site AFULGI_00013330 35c0b0852157b98de04dee3b519dc793 103 Gene3D G3DSA:2.20.25.10 3 35 9.5E-6 T 01-11-2018 AFULGI_00013330 35c0b0852157b98de04dee3b519dc793 103 Pfam PF01096 Transcription factor S-II (TFIIS) 63 100 1.2E-17 T 01-11-2018 IPR001222 Zinc finger, TFIIS-type GO:0003676|GO:0006351|GO:0008270 AFULGI_00013330 35c0b0852157b98de04dee3b519dc793 103 ProSitePatterns PS00466 Zinc finger TFIIS-type signature. 64 99 - T 01-11-2018 IPR001222 Zinc finger, TFIIS-type GO:0003676|GO:0006351|GO:0008270 AFULGI_00013330 35c0b0852157b98de04dee3b519dc793 103 TIGRFAM TIGR01384 TFS_arch: transcription factor S 2 103 1.4E-32 T 01-11-2018 IPR006288 Transcription factor S GO:0006355 AFULGI_00013330 35c0b0852157b98de04dee3b519dc793 103 Pfam PF02150 RNA polymerases M/15 Kd subunit 2 31 7.2E-14 T 01-11-2018 IPR001529 DNA-directed RNA polymerase, M/15kDa subunit GO:0006351 AFULGI_00013330 35c0b0852157b98de04dee3b519dc793 103 SUPERFAMILY SSF57783 40 103 5.21E-22 T 01-11-2018 AFULGI_00013330 35c0b0852157b98de04dee3b519dc793 103 SMART SM00440 62 101 4.7E-18 T 01-11-2018 IPR001222 Zinc finger, TFIIS-type GO:0003676|GO:0006351|GO:0008270 AFULGI_00013330 35c0b0852157b98de04dee3b519dc793 103 SMART SM00661 2 49 6.1E-19 T 01-11-2018 IPR001529 DNA-directed RNA polymerase, M/15kDa subunit GO:0006351 AFULGI_00013330 35c0b0852157b98de04dee3b519dc793 103 PIRSF PIRSF005586 1 103 2.0E-32 T 01-11-2018 IPR012164 DNA-directed RNA polymerase subunit/transcription factor S GO:0006351 AFULGI_00013330 35c0b0852157b98de04dee3b519dc793 103 Gene3D G3DSA:2.20.25.10 49 103 2.7E-23 T 01-11-2018 AFULGI_00009330 7bf241c41630474b04c0bed65b7d6496 378 Gene3D G3DSA:3.30.1490.70 74 244 1.7E-59 T 01-11-2018 AFULGI_00009330 7bf241c41630474b04c0bed65b7d6496 378 Pfam PF09414 RNA ligase 89 237 5.1E-16 T 01-11-2018 IPR021122 RNA ligase domain, REL/Rln2 AFULGI_00009330 7bf241c41630474b04c0bed65b7d6496 378 TIGRFAM TIGR01209 TIGR01209: RNA ligase, Pab1020 family 15 377 2.1E-155 T 01-11-2018 IPR001072 RNA ligase, Pab1020 family AFULGI_00009330 7bf241c41630474b04c0bed65b7d6496 378 Gene3D G3DSA:3.30.470.30 100 200 1.7E-59 T 01-11-2018 AFULGI_00009330 7bf241c41630474b04c0bed65b7d6496 378 Gene3D G3DSA:3.30.70.3350 248 374 3.9E-25 T 01-11-2018 AFULGI_00009330 7bf241c41630474b04c0bed65b7d6496 378 Gene3D G3DSA:3.30.70.3360 318 361 3.9E-25 T 01-11-2018 AFULGI_00009330 7bf241c41630474b04c0bed65b7d6496 378 SUPERFAMILY SSF56091 66 264 1.52E-37 T 01-11-2018 AFULGI_00009330 7bf241c41630474b04c0bed65b7d6496 378 PRINTS PR01048 Hypothetical protein Y414 family signature 167 188 7.2E-98 T 01-11-2018 IPR001072 RNA ligase, Pab1020 family AFULGI_00009330 7bf241c41630474b04c0bed65b7d6496 378 PRINTS PR01048 Hypothetical protein Y414 family signature 222 235 7.2E-98 T 01-11-2018 IPR001072 RNA ligase, Pab1020 family AFULGI_00009330 7bf241c41630474b04c0bed65b7d6496 378 PRINTS PR01048 Hypothetical protein Y414 family signature 354 374 7.2E-98 T 01-11-2018 IPR001072 RNA ligase, Pab1020 family AFULGI_00009330 7bf241c41630474b04c0bed65b7d6496 378 PRINTS PR01048 Hypothetical protein Y414 family signature 295 309 7.2E-98 T 01-11-2018 IPR001072 RNA ligase, Pab1020 family AFULGI_00009330 7bf241c41630474b04c0bed65b7d6496 378 PRINTS PR01048 Hypothetical protein Y414 family signature 142 157 7.2E-98 T 01-11-2018 IPR001072 RNA ligase, Pab1020 family AFULGI_00009330 7bf241c41630474b04c0bed65b7d6496 378 PRINTS PR01048 Hypothetical protein Y414 family signature 112 127 7.2E-98 T 01-11-2018 IPR001072 RNA ligase, Pab1020 family AFULGI_00009330 7bf241c41630474b04c0bed65b7d6496 378 PRINTS PR01048 Hypothetical protein Y414 family signature 264 282 7.2E-98 T 01-11-2018 IPR001072 RNA ligase, Pab1020 family AFULGI_00009330 7bf241c41630474b04c0bed65b7d6496 378 PRINTS PR01048 Hypothetical protein Y414 family signature 240 253 7.2E-98 T 01-11-2018 IPR001072 RNA ligase, Pab1020 family AFULGI_00009330 7bf241c41630474b04c0bed65b7d6496 378 PRINTS PR01048 Hypothetical protein Y414 family signature 43 57 7.2E-98 T 01-11-2018 IPR001072 RNA ligase, Pab1020 family AFULGI_00009330 7bf241c41630474b04c0bed65b7d6496 378 PRINTS PR01048 Hypothetical protein Y414 family signature 68 86 7.2E-98 T 01-11-2018 IPR001072 RNA ligase, Pab1020 family AFULGI_00009330 7bf241c41630474b04c0bed65b7d6496 378 PRINTS PR01048 Hypothetical protein Y414 family signature 91 104 7.2E-98 T 01-11-2018 IPR001072 RNA ligase, Pab1020 family AFULGI_00010670 987be5f8b35d38afed0c367c01cd285f 391 TIGRFAM TIGR00836 amt: ammonium transporter 5 390 4.7E-140 T 01-11-2018 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 AFULGI_00010670 987be5f8b35d38afed0c367c01cd285f 391 Pfam PF00909 Ammonium Transporter Family 7 390 2.5E-135 T 01-11-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 AFULGI_00010670 987be5f8b35d38afed0c367c01cd285f 391 Gene3D G3DSA:1.10.3430.10 1 391 1.7E-160 T 01-11-2018 IPR029020 Ammonium/urea transporter AFULGI_00010670 987be5f8b35d38afed0c367c01cd285f 391 SUPERFAMILY SSF111352 3 371 3.14E-118 T 01-11-2018 AFULGI_00010580 b79b0f330fcfc5599969a5600400fa2d 380 SUPERFAMILY SSF53901 7 223 7.97E-16 T 01-11-2018 IPR016039 Thiolase-like GO:0003824 AFULGI_00010580 b79b0f330fcfc5599969a5600400fa2d 380 SUPERFAMILY SSF53901 228 364 1.3E-19 T 01-11-2018 IPR016039 Thiolase-like GO:0003824 AFULGI_00010580 b79b0f330fcfc5599969a5600400fa2d 380 Gene3D G3DSA:3.40.47.10 1 379 3.9E-73 T 01-11-2018 IPR016039 Thiolase-like GO:0003824 AFULGI_00010580 b79b0f330fcfc5599969a5600400fa2d 380 Pfam PF02803 Thiolase, C-terminal domain 253 363 3.3E-6 T 01-11-2018 IPR020617 Thiolase, C-terminal GO:0016747 AFULGI_00010580 b79b0f330fcfc5599969a5600400fa2d 380 PIRSF PIRSF000429 1 364 7.5E-17 T 01-11-2018 IPR002155 Thiolase GO:0016747 AFULGI_00014530 f2750facb57ac799d152d499ddbffaf5 504 PIRSF PIRSF000478 85 498 6.7E-126 T 01-11-2018 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 AFULGI_00014530 f2750facb57ac799d152d499ddbffaf5 504 Gene3D G3DSA:3.90.1170.30 412 492 2.2E-23 T 01-11-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 AFULGI_00014530 f2750facb57ac799d152d499ddbffaf5 504 TIGRFAM TIGR03327 AMP_phos: AMP phosphorylase 3 498 8.1E-241 T 01-11-2018 IPR017713 AMP phosphorylase GO:0009032|GO:0046125 MetaCyc: PWY-5532 AFULGI_00014530 f2750facb57ac799d152d499ddbffaf5 504 SUPERFAMILY SSF50692 13 56 1.63E-6 T 01-11-2018 IPR009010 Aspartate decarboxylase-like domain superfamily AFULGI_00014530 f2750facb57ac799d152d499ddbffaf5 504 Hamap MF_02132 AMP phosphorylase. 1 502 49.002 T 01-11-2018 IPR017713 AMP phosphorylase GO:0009032|GO:0046125 MetaCyc: PWY-5532 AFULGI_00014530 f2750facb57ac799d152d499ddbffaf5 504 SMART SM00941 423 490 1.4E-20 T 01-11-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 AFULGI_00014530 f2750facb57ac799d152d499ddbffaf5 504 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 194 209 - T 01-11-2018 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 AFULGI_00014530 f2750facb57ac799d152d499ddbffaf5 504 Pfam PF00591 Glycosyl transferase family, a/b domain 160 232 8.5E-11 T 01-11-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 AFULGI_00014530 f2750facb57ac799d152d499ddbffaf5 504 SUPERFAMILY SSF52418 156 403 9.68E-67 T 01-11-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 AFULGI_00014530 f2750facb57ac799d152d499ddbffaf5 504 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 424 487 1.9E-15 T 01-11-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 AFULGI_00014530 f2750facb57ac799d152d499ddbffaf5 504 SUPERFAMILY SSF47648 87 154 4.19E-17 T 01-11-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 AFULGI_00014530 f2750facb57ac799d152d499ddbffaf5 504 SUPERFAMILY SSF54680 410 485 2.88E-16 T 01-11-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 AFULGI_00014530 f2750facb57ac799d152d499ddbffaf5 504 Gene3D G3DSA:3.40.1030.10 153 411 8.8E-94 T 01-11-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 AFULGI_00014530 f2750facb57ac799d152d499ddbffaf5 504 Pfam PF01568 Molydopterin dinucleotide binding domain 16 58 1.6E-5 T 01-11-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 AFULGI_00014530 f2750facb57ac799d152d499ddbffaf5 504 Gene3D G3DSA:2.40.40.20 1 84 5.5E-11 T 01-11-2018 AFULGI_00014530 f2750facb57ac799d152d499ddbffaf5 504 TIGRFAM TIGR02645 ARCH_P_rylase: putative thymidine phosphorylase 8 493 5.4E-192 T 01-11-2018 IPR013466 Thymidine phosphorylase/AMP phosphorylase GO:0016763 AFULGI_00014530 f2750facb57ac799d152d499ddbffaf5 504 Pfam PF02885 Glycosyl transferase family, helical bundle domain 90 151 2.5E-13 T 01-11-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 AFULGI_00014530 f2750facb57ac799d152d499ddbffaf5 504 Gene3D G3DSA:1.20.970.10 85 152 8.6E-22 T 01-11-2018 AFULGI_00021610 f31df4bcedb076b988500efcc93de36b 490 Hamap MF_01465 Protein translocase subunit SecY [secY]. 15 483 22.206 T 01-11-2018 IPR026593 Protein translocase subunit SecY AFULGI_00021610 f31df4bcedb076b988500efcc93de36b 490 Pfam PF10559 Plug domain of Sec61p 36 69 1.9E-11 T 01-11-2018 IPR019561 Translocon Sec61/SecY, plug domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 AFULGI_00021610 f31df4bcedb076b988500efcc93de36b 490 Gene3D G3DSA:1.10.3370.10 2 488 3.9E-149 T 01-11-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 AFULGI_00021610 f31df4bcedb076b988500efcc93de36b 490 ProSitePatterns PS00756 Protein secY signature 2. 167 184 - T 01-11-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 AFULGI_00021610 f31df4bcedb076b988500efcc93de36b 490 SUPERFAMILY SSF103491 5 473 1.44E-102 T 01-11-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 AFULGI_00021610 f31df4bcedb076b988500efcc93de36b 490 ProSitePatterns PS00755 Protein secY signature 1. 70 89 - T 01-11-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 AFULGI_00021610 f31df4bcedb076b988500efcc93de36b 490 Pfam PF00344 SecY translocase 70 467 2.0E-71 T 01-11-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 AFULGI_00021610 f31df4bcedb076b988500efcc93de36b 490 PRINTS PR00303 Preprotein translocase SecY subunit signature 28 46 4.2E-7 T 01-11-2018 AFULGI_00021610 f31df4bcedb076b988500efcc93de36b 490 PRINTS PR00303 Preprotein translocase SecY subunit signature 174 197 4.2E-7 T 01-11-2018 AFULGI_00021610 f31df4bcedb076b988500efcc93de36b 490 PRINTS PR00303 Preprotein translocase SecY subunit signature 148 173 4.2E-7 T 01-11-2018 AFULGI_00021610 f31df4bcedb076b988500efcc93de36b 490 PIRSF PIRSF004557 2 490 2.0E-113 T 01-11-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 AFULGI_00021610 f31df4bcedb076b988500efcc93de36b 490 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 25 476 6.8E-87 T 01-11-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 AFULGI_00011400 617d3c1264b4fde472117c045a660ecf 158 Gene3D G3DSA:2.40.50.180 34 144 5.0E-45 T 01-11-2018 AFULGI_00011400 617d3c1264b4fde472117c045a660ecf 158 SMART SM00260 11 149 1.0E-50 T 01-11-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 AFULGI_00011400 617d3c1264b4fde472117c045a660ecf 158 Pfam PF01584 CheW-like domain 15 151 2.3E-40 T 01-11-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 AFULGI_00011400 617d3c1264b4fde472117c045a660ecf 158 Gene3D G3DSA:2.30.30.40 17 143 5.0E-45 T 01-11-2018 AFULGI_00011400 617d3c1264b4fde472117c045a660ecf 158 SUPERFAMILY SSF50341 11 153 1.31E-40 T 01-11-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 AFULGI_00011100 8f47f99016d5f67b64f047f6e13c50ed 547 Gene3D G3DSA:3.50.30.80 369 519 6.4E-58 T 01-11-2018 AFULGI_00011100 8f47f99016d5f67b64f047f6e13c50ed 547 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 1 547 44.654 T 01-11-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 AFULGI_00011100 8f47f99016d5f67b64f047f6e13c50ed 547 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 119 129 - T 01-11-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 AFULGI_00011100 8f47f99016d5f67b64f047f6e13c50ed 547 Pfam PF00920 Dehydratase family 31 544 9.0E-209 T 01-11-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 AFULGI_00011100 8f47f99016d5f67b64f047f6e13c50ed 547 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 14 546 7.4E-261 T 01-11-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 AFULGI_00011100 8f47f99016d5f67b64f047f6e13c50ed 547 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 456 467 - T 01-11-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 AFULGI_00011100 8f47f99016d5f67b64f047f6e13c50ed 547 SUPERFAMILY SSF143975 1 368 6.41E-124 T 01-11-2018 IPR037237 IlvD/EDD, N-terminal domain KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 AFULGI_00011100 8f47f99016d5f67b64f047f6e13c50ed 547 SUPERFAMILY SSF52016 369 546 1.33E-61 T 01-11-2018 AFULGI_00000450 079ea83987c9151dcc4e9c27bf118314 369 Gene3D G3DSA:3.30.70.360 158 288 3.2E-61 T 01-11-2018 AFULGI_00000450 079ea83987c9151dcc4e9c27bf118314 369 SUPERFAMILY SSF53187 3 368 2.21E-45 T 01-11-2018 AFULGI_00000450 079ea83987c9151dcc4e9c27bf118314 369 Gene3D G3DSA:3.40.630.10 7 358 3.2E-61 T 01-11-2018 AFULGI_00000450 079ea83987c9151dcc4e9c27bf118314 369 Pfam PF07687 Peptidase dimerisation domain 161 266 4.5E-9 T 01-11-2018 IPR011650 Peptidase M20, dimerisation domain AFULGI_00000450 079ea83987c9151dcc4e9c27bf118314 369 Pfam PF01546 Peptidase family M20/M25/M40 62 367 3.4E-30 T 01-11-2018 IPR002933 Peptidase M20 GO:0016787 AFULGI_00000450 079ea83987c9151dcc4e9c27bf118314 369 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 61 70 - T 01-11-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 AFULGI_00000450 079ea83987c9151dcc4e9c27bf118314 369 SUPERFAMILY SSF55031 161 268 1.55E-9 T 01-11-2018 IPR036264 Bacterial exopeptidase dimerisation domain AFULGI_00002560 a32035d6bb63b74e3c129fe87edfce58 336 TIGRFAM TIGR03674 fen_arch: flap structure-specific endonuclease 1 336 1.7E-158 T 01-11-2018 IPR019973 Flap structure-specific endonuclease, archaea GO:0016788 AFULGI_00002560 a32035d6bb63b74e3c129fe87edfce58 336 Gene3D G3DSA:1.10.150.20 220 281 3.7E-23 T 01-11-2018 AFULGI_00002560 a32035d6bb63b74e3c129fe87edfce58 336 SUPERFAMILY SSF88723 6 235 5.61E-60 T 01-11-2018 IPR029060 PIN-like domain superfamily AFULGI_00002560 a32035d6bb63b74e3c129fe87edfce58 336 SUPERFAMILY SSF47807 220 336 8.82E-30 T 01-11-2018 IPR036279 5'-3' exonuclease, C-terminal domain superfamily AFULGI_00002560 a32035d6bb63b74e3c129fe87edfce58 336 SMART SM00279 222 255 1.0E-13 T 01-11-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 AFULGI_00002560 a32035d6bb63b74e3c129fe87edfce58 336 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 159 179 1.1E-34 T 01-11-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 AFULGI_00002560 a32035d6bb63b74e3c129fe87edfce58 336 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 75 94 1.1E-34 T 01-11-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 AFULGI_00002560 a32035d6bb63b74e3c129fe87edfce58 336 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 138 155 1.1E-34 T 01-11-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 AFULGI_00002560 a32035d6bb63b74e3c129fe87edfce58 336 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 21 35 1.1E-34 T 01-11-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 AFULGI_00002560 a32035d6bb63b74e3c129fe87edfce58 336 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 225 240 1.1E-34 T 01-11-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 AFULGI_00002560 a32035d6bb63b74e3c129fe87edfce58 336 Pfam PF00752 XPG N-terminal domain 13 101 4.1E-21 T 01-11-2018 IPR006085 XPG N-terminal GO:0004518|GO:0006281 AFULGI_00002560 a32035d6bb63b74e3c129fe87edfce58 336 Hamap MF_00614 Flap endonuclease 1 [fen]. 1 336 136.65 T 01-11-2018 IPR023426 Flap endonuclease 1 GO:0016788 Reactome: R-HSA-110362|Reactome: R-HSA-162594|Reactome: R-HSA-174437|Reactome: R-HSA-5651801|Reactome: R-HSA-5685939|Reactome: R-HSA-69166 AFULGI_00002560 a32035d6bb63b74e3c129fe87edfce58 336 ProSitePatterns PS00841 XPG protein signature 1. 73 87 - T 01-11-2018 IPR019974 XPG conserved site GO:0016788 AFULGI_00002560 a32035d6bb63b74e3c129fe87edfce58 336 SMART SM00484 139 220 4.2E-36 T 01-11-2018 IPR006086 XPG-I domain GO:0004518 AFULGI_00002560 a32035d6bb63b74e3c129fe87edfce58 336 SMART SM00475 22 300 0.0068 T 01-11-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 AFULGI_00002560 a32035d6bb63b74e3c129fe87edfce58 336 Pfam PF00867 XPG I-region 140 235 2.1E-27 T 01-11-2018 IPR006086 XPG-I domain GO:0004518 AFULGI_00002560 a32035d6bb63b74e3c129fe87edfce58 336 SMART SM00485 1 101 4.5E-46 T 01-11-2018 IPR006085 XPG N-terminal GO:0004518|GO:0006281 AFULGI_00002560 a32035d6bb63b74e3c129fe87edfce58 336 Gene3D G3DSA:3.40.50.1010 1 219 1.8E-84 T 01-11-2018 AFULGI_00010540 629dfbbfd9ae0c1af4ac302c390d9a88 394 Gene3D G3DSA:1.10.540.10 1 121 1.2E-33 T 01-11-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 AFULGI_00010540 629dfbbfd9ae0c1af4ac302c390d9a88 394 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 344 363 - T 01-11-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 AFULGI_00010540 629dfbbfd9ae0c1af4ac302c390d9a88 394 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 120 9.8E-29 T 01-11-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 AFULGI_00010540 629dfbbfd9ae0c1af4ac302c390d9a88 394 Gene3D G3DSA:1.20.140.10 240 392 2.8E-37 T 01-11-2018 AFULGI_00010540 629dfbbfd9ae0c1af4ac302c390d9a88 394 Gene3D G3DSA:2.40.110.10 123 239 6.0E-33 T 01-11-2018 AFULGI_00010540 629dfbbfd9ae0c1af4ac302c390d9a88 394 SUPERFAMILY SSF56645 1 247 2.88E-71 T 01-11-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 AFULGI_00010540 629dfbbfd9ae0c1af4ac302c390d9a88 394 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 124 221 5.2E-23 T 01-11-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 AFULGI_00010540 629dfbbfd9ae0c1af4ac302c390d9a88 394 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 235 386 1.2E-33 T 01-11-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AFULGI_00010540 629dfbbfd9ae0c1af4ac302c390d9a88 394 PIRSF PIRSF016578 3 103 1.2E-6 T 01-11-2018 AFULGI_00010540 629dfbbfd9ae0c1af4ac302c390d9a88 394 PIRSF PIRSF016578 235 394 1.8E-13 T 01-11-2018 AFULGI_00010540 629dfbbfd9ae0c1af4ac302c390d9a88 394 PIRSF PIRSF016578 128 202 0.06 T 01-11-2018 AFULGI_00010540 629dfbbfd9ae0c1af4ac302c390d9a88 394 SUPERFAMILY SSF47203 234 390 8.54E-43 T 01-11-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 AFULGI_00000540 f7d09c2930bee2fa590422c50c5622cb 196 SUPERFAMILY SSF52540 1 192 1.36E-46 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00000540 f7d09c2930bee2fa590422c50c5622cb 196 ProSitePatterns PS01331 Thymidylate kinase signature. 85 97 - T 01-11-2018 IPR018095 Thymidylate kinase, conserved site GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 AFULGI_00000540 f7d09c2930bee2fa590422c50c5622cb 196 Hamap MF_00165 Thymidylate kinase [tmk]. 1 189 24.618 T 01-11-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 AFULGI_00000540 f7d09c2930bee2fa590422c50c5622cb 196 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 1 181 1.6E-61 T 01-11-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 AFULGI_00000540 f7d09c2930bee2fa590422c50c5622cb 196 Gene3D G3DSA:3.40.50.300 1 192 2.3E-61 T 01-11-2018 AFULGI_00000540 f7d09c2930bee2fa590422c50c5622cb 196 Pfam PF02223 Thymidylate kinase 5 181 1.6E-56 T 01-11-2018 IPR039430 Thymidylate kinase-like domain KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 AFULGI_00000020 b41f8bd8b583a72e7c665632b2eac9ac 586 Pfam PF00005 ABC transporter 357 478 6.4E-17 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFULGI_00000020 b41f8bd8b583a72e7c665632b2eac9ac 586 SUPERFAMILY SSF52540 333 525 1.33E-35 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00000020 b41f8bd8b583a72e7c665632b2eac9ac 586 ProSitePatterns PS00211 ABC transporters family signature. 450 464 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFULGI_00000020 b41f8bd8b583a72e7c665632b2eac9ac 586 Gene3D G3DSA:3.40.50.300 327 585 3.4E-53 T 01-11-2018 AFULGI_00000020 b41f8bd8b583a72e7c665632b2eac9ac 586 SUPERFAMILY SSF52540 87 279 4.23E-34 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00000020 b41f8bd8b583a72e7c665632b2eac9ac 586 Pfam PF00037 4Fe-4S binding domain 43 64 3.6E-7 T 01-11-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFULGI_00000020 b41f8bd8b583a72e7c665632b2eac9ac 586 Gene3D G3DSA:3.40.50.300 1 323 2.8E-78 T 01-11-2018 AFULGI_00000020 b41f8bd8b583a72e7c665632b2eac9ac 586 SMART SM00382 96 285 2.5E-9 T 01-11-2018 IPR003593 AAA+ ATPase domain AFULGI_00000020 b41f8bd8b583a72e7c665632b2eac9ac 586 SMART SM00382 360 528 1.8E-5 T 01-11-2018 IPR003593 AAA+ ATPase domain AFULGI_00000020 b41f8bd8b583a72e7c665632b2eac9ac 586 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 49 60 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFULGI_00000020 b41f8bd8b583a72e7c665632b2eac9ac 586 PRINTS PR01868 ABC transporter family E signature 101 126 4.1E-55 T 01-11-2018 IPR013283 RLI1 Reactome: R-HSA-909733 AFULGI_00000020 b41f8bd8b583a72e7c665632b2eac9ac 586 PRINTS PR01868 ABC transporter family E signature 73 93 4.1E-55 T 01-11-2018 IPR013283 RLI1 Reactome: R-HSA-909733 AFULGI_00000020 b41f8bd8b583a72e7c665632b2eac9ac 586 PRINTS PR01868 ABC transporter family E signature 132 148 4.1E-55 T 01-11-2018 IPR013283 RLI1 Reactome: R-HSA-909733 AFULGI_00000020 b41f8bd8b583a72e7c665632b2eac9ac 586 PRINTS PR01868 ABC transporter family E signature 148 174 4.1E-55 T 01-11-2018 IPR013283 RLI1 Reactome: R-HSA-909733 AFULGI_00000020 b41f8bd8b583a72e7c665632b2eac9ac 586 PRINTS PR01868 ABC transporter family E signature 21 36 4.1E-55 T 01-11-2018 IPR013283 RLI1 Reactome: R-HSA-909733 AFULGI_00000020 b41f8bd8b583a72e7c665632b2eac9ac 586 PRINTS PR01868 ABC transporter family E signature 46 70 4.1E-55 T 01-11-2018 IPR013283 RLI1 Reactome: R-HSA-909733 AFULGI_00000020 b41f8bd8b583a72e7c665632b2eac9ac 586 Pfam PF04068 Possible Fer4-like domain in RNase L inhibitor, RLI 4 34 9.0E-13 T 01-11-2018 IPR007209 RNase L inhibitor RLI, possible metal-binding domain AFULGI_00000020 b41f8bd8b583a72e7c665632b2eac9ac 586 ProSitePatterns PS00211 ABC transporters family signature. 209 223 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFULGI_00000020 b41f8bd8b583a72e7c665632b2eac9ac 586 Pfam PF00005 ABC transporter 96 237 1.2E-17 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFULGI_00000020 b41f8bd8b583a72e7c665632b2eac9ac 586 SUPERFAMILY SSF54862 6 123 1.41E-20 T 01-11-2018 AFULGI_00018610 e52efbfc432182d653c60c06b00cb5bb 112 TIGRFAM TIGR03330 SAM_DCase_Bsu: S-adenosylmethionine decarboxylase proenzyme 2 112 2.3E-42 T 01-11-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 AFULGI_00018610 e52efbfc432182d653c60c06b00cb5bb 112 Gene3D G3DSA:3.60.90.10 1 112 1.3E-42 T 01-11-2018 AFULGI_00018610 e52efbfc432182d653c60c06b00cb5bb 112 Pfam PF02675 S-adenosylmethionine decarboxylase 6 112 1.6E-35 T 01-11-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 AFULGI_00018610 e52efbfc432182d653c60c06b00cb5bb 112 Hamap MF_00464 S-adenosylmethionine decarboxylase proenzyme [speH]. 1 112 26.753 T 01-11-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 AFULGI_00018610 e52efbfc432182d653c60c06b00cb5bb 112 SUPERFAMILY SSF56276 2 112 9.42E-37 T 01-11-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 AFULGI_00025460 b4f0fbdf40519aa779accfd28abef3c6 390 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 113 124 - T 01-11-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 AFULGI_00025460 b4f0fbdf40519aa779accfd28abef3c6 390 SUPERFAMILY SSF52402 1 199 2.87E-44 T 01-11-2018 AFULGI_00025460 b4f0fbdf40519aa779accfd28abef3c6 390 TIGRFAM TIGR00032 argG: argininosuccinate synthase 2 388 9.8E-179 T 01-11-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 AFULGI_00025460 b4f0fbdf40519aa779accfd28abef3c6 390 Gene3D G3DSA:3.40.50.620 1 167 3.6E-54 T 01-11-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFULGI_00025460 b4f0fbdf40519aa779accfd28abef3c6 390 SUPERFAMILY SSF69864 165 388 6.93E-90 T 01-11-2018 AFULGI_00025460 b4f0fbdf40519aa779accfd28abef3c6 390 Hamap MF_00005 Argininosuccinate synthase [argG]. 1 390 49.343 T 01-11-2018 IPR023434 Argininosuccinate synthase, type 1 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 AFULGI_00025460 b4f0fbdf40519aa779accfd28abef3c6 390 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 6 14 - T 01-11-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 AFULGI_00025460 b4f0fbdf40519aa779accfd28abef3c6 390 Gene3D G3DSA:3.90.1260.10 168 389 2.3E-89 T 01-11-2018 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 AFULGI_00025460 b4f0fbdf40519aa779accfd28abef3c6 390 Pfam PF00764 Arginosuccinate synthase 4 385 1.5E-181 T 01-11-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 AFULGI_00003930 f4ee70072170d90ea8439999f80c3d96 484 Pfam PF09847 Membrane protein of 12 TMs 39 477 7.4E-132 T 01-11-2018 IPR018646 Membrane protein of 12 TMs AFULGI_00003930 f4ee70072170d90ea8439999f80c3d96 484 PIRSF PIRSF018875 1 482 1.3E-156 T 01-11-2018 IPR018646 Membrane protein of 12 TMs AFULGI_00004160 80af5ca2bcf5e6ccbef351ace4fa5b12 467 SUPERFAMILY SSF47323 347 466 4.84E-28 T 01-11-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFULGI_00004160 80af5ca2bcf5e6ccbef351ace4fa5b12 467 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 1 465 3.1E-189 T 01-11-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 AFULGI_00004160 80af5ca2bcf5e6ccbef351ace4fa5b12 467 Gene3D G3DSA:3.40.50.620 1 307 1.0E-130 T 01-11-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFULGI_00004160 80af5ca2bcf5e6ccbef351ace4fa5b12 467 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 1 467 36.964 T 01-11-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 AFULGI_00004160 80af5ca2bcf5e6ccbef351ace4fa5b12 467 Gene3D G3DSA:1.20.120.640 308 466 2.3E-30 T 01-11-2018 AFULGI_00004160 80af5ca2bcf5e6ccbef351ace4fa5b12 467 Pfam PF09190 DALR domain 355 411 4.3E-13 T 01-11-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 AFULGI_00004160 80af5ca2bcf5e6ccbef351ace4fa5b12 467 SMART SM00840 355 417 4.1E-17 T 01-11-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 AFULGI_00004160 80af5ca2bcf5e6ccbef351ace4fa5b12 467 SUPERFAMILY SSF52374 2 315 1.54E-94 T 01-11-2018 AFULGI_00004160 80af5ca2bcf5e6ccbef351ace4fa5b12 467 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 193 211 1.5E-27 T 01-11-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 AFULGI_00004160 80af5ca2bcf5e6ccbef351ace4fa5b12 467 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 25 36 1.5E-27 T 01-11-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 AFULGI_00004160 80af5ca2bcf5e6ccbef351ace4fa5b12 467 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 224 245 1.5E-27 T 01-11-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 AFULGI_00004160 80af5ca2bcf5e6ccbef351ace4fa5b12 467 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 61 70 1.5E-27 T 01-11-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 AFULGI_00004160 80af5ca2bcf5e6ccbef351ace4fa5b12 467 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 18 315 1.1E-138 T 01-11-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 AFULGI_00025690 258c6774a3456a5c51268d1434b2e5cf 240 Gene3D G3DSA:3.50.50.60 106 202 8.8E-16 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFULGI_00025690 258c6774a3456a5c51268d1434b2e5cf 240 SUPERFAMILY SSF51905 5 210 5.18E-19 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFULGI_00025690 258c6774a3456a5c51268d1434b2e5cf 240 Gene3D G3DSA:3.50.50.60 5 207 8.8E-16 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFULGI_00025690 258c6774a3456a5c51268d1434b2e5cf 240 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 129 1.8E-9 T 01-11-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFULGI_00010530 b94c1ace881e44ccb14833daabd7c206 259 Gene3D G3DSA:1.10.12.10 200 255 1.4E-20 T 01-11-2018 IPR014748 Enoyl-CoA hydratase, C-terminal AFULGI_00010530 b94c1ace881e44ccb14833daabd7c206 259 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 98 118 - T 01-11-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 AFULGI_00010530 b94c1ace881e44ccb14833daabd7c206 259 Gene3D G3DSA:3.90.226.10 1 198 9.2E-79 T 01-11-2018 AFULGI_00010530 b94c1ace881e44ccb14833daabd7c206 259 Pfam PF00378 Enoyl-CoA hydratase/isomerase 8 255 1.5E-78 T 01-11-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 AFULGI_00010530 b94c1ace881e44ccb14833daabd7c206 259 SUPERFAMILY SSF52096 3 256 7.47E-96 T 01-11-2018 IPR029045 ClpP/crotonase-like domain superfamily AFULGI_00009960 8422cc69a2a67d51504d77e91aace588 289 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 4 284 9.2E-122 T 01-11-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AFULGI_00009960 8422cc69a2a67d51504d77e91aace588 289 Gene3D G3DSA:3.20.20.70 1 288 2.8E-113 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFULGI_00009960 8422cc69a2a67d51504d77e91aace588 289 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 37 54 - T 01-11-2018 IPR020624 Schiff base-forming aldolase, conserved site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AFULGI_00009960 8422cc69a2a67d51504d77e91aace588 289 SUPERFAMILY SSF51569 2 285 1.36E-102 T 01-11-2018 AFULGI_00009960 8422cc69a2a67d51504d77e91aace588 289 PIRSF PIRSF001365 1 288 7.9E-95 T 01-11-2018 IPR002220 DapA-like GO:0016829 AFULGI_00009960 8422cc69a2a67d51504d77e91aace588 289 SMART SM01130 1 286 3.1E-143 T 01-11-2018 IPR002220 DapA-like GO:0016829 AFULGI_00009960 8422cc69a2a67d51504d77e91aace588 289 PRINTS PR00146 Dihydrodipicolinate synthase signature 34 55 3.1E-34 T 01-11-2018 IPR002220 DapA-like GO:0016829 AFULGI_00009960 8422cc69a2a67d51504d77e91aace588 289 PRINTS PR00146 Dihydrodipicolinate synthase signature 100 116 3.1E-34 T 01-11-2018 IPR002220 DapA-like GO:0016829 AFULGI_00009960 8422cc69a2a67d51504d77e91aace588 289 PRINTS PR00146 Dihydrodipicolinate synthase signature 68 86 3.1E-34 T 01-11-2018 IPR002220 DapA-like GO:0016829 AFULGI_00009960 8422cc69a2a67d51504d77e91aace588 289 PRINTS PR00146 Dihydrodipicolinate synthase signature 125 142 3.1E-34 T 01-11-2018 IPR002220 DapA-like GO:0016829 AFULGI_00009960 8422cc69a2a67d51504d77e91aace588 289 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 130 160 - T 01-11-2018 IPR020625 Schiff base-forming aldolase, active site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 AFULGI_00009960 8422cc69a2a67d51504d77e91aace588 289 Pfam PF00701 Dihydrodipicolinate synthetase family 2 284 1.2E-98 T 01-11-2018 IPR002220 DapA-like GO:0016829 AFULGI_00009960 8422cc69a2a67d51504d77e91aace588 289 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 1 284 64.868 T 01-11-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AFULGI_00006160 11596e4b1deed0250dc504ae90671446 345 Gene3D G3DSA:3.90.190.10 9 164 1.4E-22 T 01-11-2018 IPR029021 Protein-tyrosine phosphatase-like AFULGI_00006160 11596e4b1deed0250dc504ae90671446 345 Gene3D G3DSA:3.40.50.1440 174 345 2.4E-8 T 01-11-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 AFULGI_00006160 11596e4b1deed0250dc504ae90671446 345 ProSitePatterns PS00383 Tyrosine specific protein phosphatases active site. 113 123 - T 01-11-2018 IPR016130 Protein-tyrosine phosphatase, active site GO:0004725|GO:0016311 AFULGI_00006160 11596e4b1deed0250dc504ae90671446 345 SUPERFAMILY SSF52490 183 330 3.2E-8 T 01-11-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 AFULGI_00006160 11596e4b1deed0250dc504ae90671446 345 Pfam PF00782 Dual specificity phosphatase, catalytic domain 71 147 1.4E-9 T 01-11-2018 IPR000340 Dual specificity phosphatase, catalytic domain GO:0008138|GO:0016311 AFULGI_00006160 11596e4b1deed0250dc504ae90671446 345 SUPERFAMILY SSF52799 31 147 2.45E-22 T 01-11-2018 IPR029021 Protein-tyrosine phosphatase-like AFULGI_00023010 ba9abde44d68c0b5ef8be7766faa5cf0 453 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 5 106 2.3E-23 T 01-11-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 AFULGI_00023010 ba9abde44d68c0b5ef8be7766faa5cf0 453 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 237 418 1.0E-38 T 01-11-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFULGI_00023010 ba9abde44d68c0b5ef8be7766faa5cf0 453 SUPERFAMILY SSF46589 6 112 7.85E-27 T 01-11-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 AFULGI_00023010 ba9abde44d68c0b5ef8be7766faa5cf0 453 Hamap MF_00176 Serine--tRNA ligase [serS]. 2 441 40.167 T 01-11-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 AFULGI_00023010 ba9abde44d68c0b5ef8be7766faa5cf0 453 PIRSF PIRSF001529 4 445 9.1E-145 T 01-11-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 AFULGI_00023010 ba9abde44d68c0b5ef8be7766faa5cf0 453 Gene3D G3DSA:3.30.930.10 105 446 1.3E-126 T 01-11-2018 AFULGI_00023010 ba9abde44d68c0b5ef8be7766faa5cf0 453 PRINTS PR00981 Seryl-tRNA synthetase signature 369 385 2.4E-34 T 01-11-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 AFULGI_00023010 ba9abde44d68c0b5ef8be7766faa5cf0 453 PRINTS PR00981 Seryl-tRNA synthetase signature 294 307 2.4E-34 T 01-11-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 AFULGI_00023010 ba9abde44d68c0b5ef8be7766faa5cf0 453 PRINTS PR00981 Seryl-tRNA synthetase signature 351 367 2.4E-34 T 01-11-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 AFULGI_00023010 ba9abde44d68c0b5ef8be7766faa5cf0 453 PRINTS PR00981 Seryl-tRNA synthetase signature 334 347 2.4E-34 T 01-11-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 AFULGI_00023010 ba9abde44d68c0b5ef8be7766faa5cf0 453 PRINTS PR00981 Seryl-tRNA synthetase signature 282 294 2.4E-34 T 01-11-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 AFULGI_00023010 ba9abde44d68c0b5ef8be7766faa5cf0 453 Gene3D G3DSA:1.10.287.40 5 104 4.7E-24 T 01-11-2018 AFULGI_00023010 ba9abde44d68c0b5ef8be7766faa5cf0 453 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 436 5.9E-177 T 01-11-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 AFULGI_00023010 ba9abde44d68c0b5ef8be7766faa5cf0 453 SUPERFAMILY SSF55681 150 436 2.25E-84 T 01-11-2018 AFULGI_00008720 f0d2b994a4835d6f839c2d5e27fc9d4f 184 Gene3D G3DSA:3.40.50.150 1 184 3.0E-38 T 01-11-2018 AFULGI_00008720 f0d2b994a4835d6f839c2d5e27fc9d4f 184 SUPERFAMILY SSF53335 2 173 1.45E-26 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFULGI_00008720 f0d2b994a4835d6f839c2d5e27fc9d4f 184 Pfam PF08241 Methyltransferase domain 38 114 6.7E-12 T 01-11-2018 IPR013216 Methyltransferase type 11 GO:0008168 AFULGI_00021180 4160ef65a8ae0fd1cd1bcac8e2785603 352 TIGRFAM TIGR02580 cas_RAMP_Cmr4: CRISPR type III-B/RAMP module RAMP protein Cmr4 7 339 9.0E-80 T 01-11-2018 IPR013410 CRISPR-associated RAMP Cmr4 AFULGI_00021180 4160ef65a8ae0fd1cd1bcac8e2785603 352 Pfam PF03787 RAMP superfamily 11 339 1.2E-31 T 01-11-2018 IPR005537 CRISPR type III-associated RAMP protein AFULGI_00018440 da36c12b2c492f134bc0555cb82125f5 304 Pfam PF01171 PP-loop family 51 239 1.8E-10 T 01-11-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 AFULGI_00018440 da36c12b2c492f134bc0555cb82125f5 304 SUPERFAMILY SSF52402 26 250 5.29E-51 T 01-11-2018 AFULGI_00018440 da36c12b2c492f134bc0555cb82125f5 304 PIRSF PIRSF004976 1 304 1.1E-107 T 01-11-2018 IPR035107 tRNA thiolation protein, TtcA/Ctu1 type GO:0008033 Reactome: R-HSA-6782315 AFULGI_00018440 da36c12b2c492f134bc0555cb82125f5 304 TIGRFAM TIGR00269 TIGR00269: TIGR00269 family protein 197 300 8.1E-49 T 01-11-2018 IPR000541 Cytoplasmic tRNA 2-thiolation protein 1 GO:0000049|GO:0002098|GO:0034227 Reactome: R-HSA-6782315 AFULGI_00018440 da36c12b2c492f134bc0555cb82125f5 304 Gene3D G3DSA:3.40.50.620 2 304 1.1E-80 T 01-11-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFULGI_00018440 da36c12b2c492f134bc0555cb82125f5 304 ProSitePatterns PS01263 Uncharacterized protein family UPF0021 signature. 23 60 - T 01-11-2018 IPR020554 Uncharacterised protein family UPF0021, conserved site AFULGI_00026040 863e5539726e8473bd57bd14f3847c26 72 Gene3D G3DSA:1.20.120.330 1 71 1.2E-12 T 01-11-2018 AFULGI_00026040 863e5539726e8473bd57bd14f3847c26 72 Pfam PF05168 HEPN domain 5 51 4.7E-11 T 01-11-2018 IPR007842 HEPN domain AFULGI_00026040 863e5539726e8473bd57bd14f3847c26 72 SUPERFAMILY SSF81593 3 66 1.26E-10 T 01-11-2018 AFULGI_00026760 699143aabfc603e7851cd8cf4af43faf 425 Gene3D G3DSA:3.20.20.540 44 358 4.7E-141 T 01-11-2018 IPR038521 ThiC/Bza superfamily KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 AFULGI_00026760 699143aabfc603e7851cd8cf4af43faf 425 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 1 422 2.7E-215 T 01-11-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 AFULGI_00026760 699143aabfc603e7851cd8cf4af43faf 425 Pfam PF01964 Radical SAM ThiC family 2 419 4.9E-185 T 01-11-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 AFULGI_00026760 699143aabfc603e7851cd8cf4af43faf 425 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 1 424 84.68 T 01-11-2018 IPR037509 Phosphomethylpyrimidine synthase GO:0009228|GO:0016830 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 AFULGI_00002320 8dc0fbba0cfedf40bb4f764a712a3176 639 SUPERFAMILY SSF52540 16 172 1.48E-34 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00002320 8dc0fbba0cfedf40bb4f764a712a3176 639 Gene3D G3DSA:3.40.50.300 13 192 4.4E-40 T 01-11-2018 AFULGI_00002320 8dc0fbba0cfedf40bb4f764a712a3176 639 Pfam PF02421 Ferrous iron transport protein B 16 164 1.6E-48 T 01-11-2018 IPR030389 FeoB-type guanine nucleotide-binding (G) domain GO:0005525 AFULGI_00002320 8dc0fbba0cfedf40bb4f764a712a3176 639 Pfam PF07670 Nucleoside recognition 357 447 5.3E-11 T 01-11-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 AFULGI_00002320 8dc0fbba0cfedf40bb4f764a712a3176 639 Pfam PF07670 Nucleoside recognition 511 611 1.7E-9 T 01-11-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 AFULGI_00002320 8dc0fbba0cfedf40bb4f764a712a3176 639 Pfam PF07664 Ferrous iron transport protein B C terminus 454 505 6.3E-10 T 01-11-2018 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 AFULGI_00002320 8dc0fbba0cfedf40bb4f764a712a3176 639 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 17 37 1.9E-6 T 01-11-2018 IPR006073 GTP binding domain GO:0005525 AFULGI_00002320 8dc0fbba0cfedf40bb4f764a712a3176 639 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 38 56 1.9E-6 T 01-11-2018 IPR006073 GTP binding domain GO:0005525 AFULGI_00002320 8dc0fbba0cfedf40bb4f764a712a3176 639 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 127 3.4E-15 T 01-11-2018 IPR005225 Small GTP-binding protein domain GO:0005525 AFULGI_00002320 8dc0fbba0cfedf40bb4f764a712a3176 639 TIGRFAM TIGR00437 feoB: ferrous iron transport protein B 21 608 5.0E-179 T 01-11-2018 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 AFULGI_00014160 204a3343b3a9ef95259f0e3835dd39af 394 Gene3D G3DSA:3.30.230.60 1 165 2.4E-69 T 01-11-2018 IPR037075 Formaldehyde-activating enzyme superfamily GO:0016051|GO:0016840 KEGG: 00030+4.1.2.43|KEGG: 00680+4.2.1.147+4.1.2.43|MetaCyc: PWY-1723|MetaCyc: PWY-1861|MetaCyc: PWY-7796 AFULGI_00014160 204a3343b3a9ef95259f0e3835dd39af 394 Pfam PF08714 Formaldehyde-activating enzyme (Fae) 5 162 5.1E-70 T 01-11-2018 IPR014826 Formaldehyde-activating enzyme GO:0016051|GO:0016840 KEGG: 00030+4.1.2.43|KEGG: 00680+4.2.1.147+4.1.2.43|MetaCyc: PWY-1723|MetaCyc: PWY-1861|MetaCyc: PWY-7796 AFULGI_00014160 204a3343b3a9ef95259f0e3835dd39af 394 SUPERFAMILY SSF51366 97 382 1.74E-47 T 01-11-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 AFULGI_00014160 204a3343b3a9ef95259f0e3835dd39af 394 Gene3D G3DSA:3.20.20.70 175 383 1.5E-58 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFULGI_00014160 204a3343b3a9ef95259f0e3835dd39af 394 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 175 376 3.7E-23 T 01-11-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AFULGI_00014160 204a3343b3a9ef95259f0e3835dd39af 394 SUPERFAMILY SSF54211 2 164 1.14E-67 T 01-11-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFULGI_00014160 204a3343b3a9ef95259f0e3835dd39af 394 Hamap MF_01268 Bifunctional enzyme Fae/Hps [fae-hps]. 1 394 208.634 T 01-11-2018 IPR020868 Bifunctional enzyme Fae/Hps GO:0016051|GO:0016832|GO:0016840 KEGG: 00030+4.1.2.43|KEGG: 00680+4.2.1.147+4.1.2.43|MetaCyc: PWY-1723|MetaCyc: PWY-1861|MetaCyc: PWY-7796 AFULGI_00014160 204a3343b3a9ef95259f0e3835dd39af 394 SMART SM00934 175 377 2.0E-36 T 01-11-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AFULGI_00014160 204a3343b3a9ef95259f0e3835dd39af 394 TIGRFAM TIGR03126 one_C_fae: formaldehyde-activating enzyme 3 162 4.4E-81 T 01-11-2018 IPR014826 Formaldehyde-activating enzyme GO:0016051|GO:0016840 KEGG: 00030+4.1.2.43|KEGG: 00680+4.2.1.147+4.1.2.43|MetaCyc: PWY-1723|MetaCyc: PWY-1861|MetaCyc: PWY-7796 AFULGI_00017950 214275eed069906f6201505eaf4cad5c 372 Pfam PF07690 Major Facilitator Superfamily 28 220 6.4E-12 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFULGI_00017950 214275eed069906f6201505eaf4cad5c 372 Gene3D G3DSA:1.20.1250.20 2 196 1.1E-17 T 01-11-2018 AFULGI_00017950 214275eed069906f6201505eaf4cad5c 372 SUPERFAMILY SSF103473 8 367 1.28E-35 T 01-11-2018 IPR036259 MFS transporter superfamily AFULGI_00017950 214275eed069906f6201505eaf4cad5c 372 Gene3D G3DSA:1.20.1250.20 200 371 2.1E-13 T 01-11-2018 AFULGI_00017810 19ab862585ed7a694fbcc766995d454b 438 Pfam PF01629 Domain of unknown function DUF22 288 391 5.4E-37 T 01-11-2018 IPR002572 Domain of unknown function DUF22 AFULGI_00017810 19ab862585ed7a694fbcc766995d454b 438 Pfam PF01629 Domain of unknown function DUF22 3 110 3.1E-38 T 01-11-2018 IPR002572 Domain of unknown function DUF22 AFULGI_00017810 19ab862585ed7a694fbcc766995d454b 438 Pfam PF01629 Domain of unknown function DUF22 150 255 5.5E-42 T 01-11-2018 IPR002572 Domain of unknown function DUF22 AFULGI_00013810 d9547028883b9d8384a4a7766d3827bb 358 Pfam PF00117 Glutamine amidotransferase class-I 176 352 1.5E-50 T 01-11-2018 IPR017926 Glutamine amidotransferase AFULGI_00013810 d9547028883b9d8384a4a7766d3827bb 358 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 3 130 5.2E-53 T 01-11-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFULGI_00013810 d9547028883b9d8384a4a7766d3827bb 358 SMART SM01097 1 131 9.9E-90 T 01-11-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFULGI_00013810 d9547028883b9d8384a4a7766d3827bb 358 PRINTS PR00097 Anthranilate synthase component II signature 329 342 2.2E-5 T 01-11-2018 AFULGI_00013810 d9547028883b9d8384a4a7766d3827bb 358 PRINTS PR00097 Anthranilate synthase component II signature 244 255 2.2E-5 T 01-11-2018 AFULGI_00013810 d9547028883b9d8384a4a7766d3827bb 358 PRINTS PR00097 Anthranilate synthase component II signature 217 226 2.2E-5 T 01-11-2018 AFULGI_00013810 d9547028883b9d8384a4a7766d3827bb 358 Gene3D G3DSA:3.40.50.880 149 358 3.9E-67 T 01-11-2018 IPR029062 Class I glutamine amidotransferase-like AFULGI_00013810 d9547028883b9d8384a4a7766d3827bb 358 PRINTS PR00096 Glutamine amidotransferase superfamily signature 217 226 9.7E-11 T 01-11-2018 AFULGI_00013810 d9547028883b9d8384a4a7766d3827bb 358 PRINTS PR00096 Glutamine amidotransferase superfamily signature 244 255 9.7E-11 T 01-11-2018 AFULGI_00013810 d9547028883b9d8384a4a7766d3827bb 358 PRINTS PR00096 Glutamine amidotransferase superfamily signature 329 342 9.7E-11 T 01-11-2018 AFULGI_00013810 d9547028883b9d8384a4a7766d3827bb 358 SUPERFAMILY SSF52021 1 143 1.31E-55 T 01-11-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFULGI_00013810 d9547028883b9d8384a4a7766d3827bb 358 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 286 297 1.3E-37 T 01-11-2018 AFULGI_00013810 d9547028883b9d8384a4a7766d3827bb 358 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 175 189 1.3E-37 T 01-11-2018 AFULGI_00013810 d9547028883b9d8384a4a7766d3827bb 358 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 244 260 1.3E-37 T 01-11-2018 AFULGI_00013810 d9547028883b9d8384a4a7766d3827bb 358 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 214 228 1.3E-37 T 01-11-2018 AFULGI_00013810 d9547028883b9d8384a4a7766d3827bb 358 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 261 278 1.3E-37 T 01-11-2018 AFULGI_00013810 d9547028883b9d8384a4a7766d3827bb 358 Gene3D G3DSA:3.50.30.20 1 148 1.2E-58 T 01-11-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFULGI_00013810 d9547028883b9d8384a4a7766d3827bb 358 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 1 358 49.022 T 01-11-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFULGI_00013810 d9547028883b9d8384a4a7766d3827bb 358 SUPERFAMILY SSF52317 152 357 4.03E-58 T 01-11-2018 IPR029062 Class I glutamine amidotransferase-like AFULGI_00013810 d9547028883b9d8384a4a7766d3827bb 358 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 3 355 8.5E-157 T 01-11-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFULGI_00008560 4ffe640d57cdd0889aee5e0aefe39b97 323 PIRSF PIRSF006588 1 322 7.4E-130 T 01-11-2018 IPR023617 Tyrosine-tRNA ligase, archaeal/eukaryotic-type GO:0004831 KEGG: 00970+6.1.1.1 AFULGI_00008560 4ffe640d57cdd0889aee5e0aefe39b97 323 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 41 50 - T 01-11-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFULGI_00008560 4ffe640d57cdd0889aee5e0aefe39b97 323 SUPERFAMILY SSF52374 2 319 5.63E-82 T 01-11-2018 AFULGI_00008560 4ffe640d57cdd0889aee5e0aefe39b97 323 Pfam PF00579 tRNA synthetases class I (W and Y) 30 312 6.2E-61 T 01-11-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFULGI_00008560 4ffe640d57cdd0889aee5e0aefe39b97 323 Hamap MF_02008 Tyrosine--tRNA ligase [tyrS]. 4 320 55.195 T 01-11-2018 IPR023684 Tyrosine-tRNA ligase, type 3 GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 AFULGI_00008560 4ffe640d57cdd0889aee5e0aefe39b97 323 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 167 189 4.3E-20 T 01-11-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 AFULGI_00008560 4ffe640d57cdd0889aee5e0aefe39b97 323 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 200 212 4.3E-20 T 01-11-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 AFULGI_00008560 4ffe640d57cdd0889aee5e0aefe39b97 323 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 150 165 4.3E-20 T 01-11-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 AFULGI_00008560 4ffe640d57cdd0889aee5e0aefe39b97 323 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 44 66 4.3E-20 T 01-11-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 AFULGI_00008560 4ffe640d57cdd0889aee5e0aefe39b97 323 Gene3D G3DSA:3.40.50.620 1 205 2.2E-84 T 01-11-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFULGI_00008560 4ffe640d57cdd0889aee5e0aefe39b97 323 Gene3D G3DSA:1.10.240.10 206 322 5.0E-41 T 01-11-2018 AFULGI_00008560 4ffe640d57cdd0889aee5e0aefe39b97 323 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 2 318 2.1E-81 T 01-11-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 AFULGI_00000010 976dbd75957cf713a8359861c550e90f 164 Gene3D G3DSA:3.40.33.10 22 159 9.0E-19 T 01-11-2018 IPR035940 CAP superfamily AFULGI_00000010 976dbd75957cf713a8359861c550e90f 164 Pfam PF00188 Cysteine-rich secretory protein family 41 155 1.1E-10 T 01-11-2018 IPR014044 CAP domain AFULGI_00000010 976dbd75957cf713a8359861c550e90f 164 SUPERFAMILY SSF55797 33 152 7.59E-11 T 01-11-2018 IPR035940 CAP superfamily AFULGI_00008990 72d4e4ba993b32b82f4aa00c11ff8443 527 Pfam PF01842 ACT domain 454 517 1.1E-14 T 01-11-2018 IPR002912 ACT domain AFULGI_00008990 72d4e4ba993b32b82f4aa00c11ff8443 527 Gene3D G3DSA:3.40.50.720 92 282 2.4E-127 T 01-11-2018 AFULGI_00008990 72d4e4ba993b32b82f4aa00c11ff8443 527 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 190 212 - T 01-11-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site AFULGI_00008990 72d4e4ba993b32b82f4aa00c11ff8443 527 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 219 235 - T 01-11-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site AFULGI_00008990 72d4e4ba993b32b82f4aa00c11ff8443 527 SUPERFAMILY SSF51735 99 281 1.51E-63 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily AFULGI_00008990 72d4e4ba993b32b82f4aa00c11ff8443 527 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 105 280 9.4E-68 T 01-11-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 AFULGI_00008990 72d4e4ba993b32b82f4aa00c11ff8443 527 Gene3D G3DSA:3.30.70.260 452 527 7.7E-16 T 01-11-2018 AFULGI_00008990 72d4e4ba993b32b82f4aa00c11ff8443 527 Gene3D G3DSA:3.40.50.720 3 291 2.4E-127 T 01-11-2018 AFULGI_00008990 72d4e4ba993b32b82f4aa00c11ff8443 527 TIGRFAM TIGR01327 PGDH: phosphoglycerate dehydrogenase 2 527 1.6E-233 T 01-11-2018 IPR006236 D-3-phosphoglycerate dehydrogenase GO:0004617|GO:0006564 KEGG: 00260+1.1.1.95|KEGG: 00680+1.1.1.95|Reactome: R-HSA-977347 AFULGI_00008990 72d4e4ba993b32b82f4aa00c11ff8443 527 SUPERFAMILY SSF143548 319 447 7.85E-33 T 01-11-2018 IPR029009 Allosteric substrate binding domain superfamily Reactome: R-HSA-977347 AFULGI_00008990 72d4e4ba993b32b82f4aa00c11ff8443 527 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 449 520 5.0E-6 T 01-11-2018 AFULGI_00008990 72d4e4ba993b32b82f4aa00c11ff8443 527 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 3 312 2.0E-44 T 01-11-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 AFULGI_00008990 72d4e4ba993b32b82f4aa00c11ff8443 527 SUPERFAMILY SSF52283 1 134 4.16E-42 T 01-11-2018 AFULGI_00008990 72d4e4ba993b32b82f4aa00c11ff8443 527 SUPERFAMILY SSF55021 444 525 3.6E-18 T 01-11-2018 AFULGI_00008990 72d4e4ba993b32b82f4aa00c11ff8443 527 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 142 169 - T 01-11-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 AFULGI_00008990 72d4e4ba993b32b82f4aa00c11ff8443 527 Gene3D G3DSA:3.30.1330.90 321 451 1.8E-33 T 01-11-2018 IPR029009 Allosteric substrate binding domain superfamily Reactome: R-HSA-977347 AFULGI_00025940 fa97ca4007ec488c73c5cf818bbbb1fb 453 SUPERFAMILY SSF53383 1 392 6.86E-92 T 01-11-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFULGI_00025940 fa97ca4007ec488c73c5cf818bbbb1fb 453 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 70 315 3.8E-18 T 01-11-2018 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 AFULGI_00025940 fa97ca4007ec488c73c5cf818bbbb1fb 453 Gene3D G3DSA:3.90.1150.10 4 384 2.4E-100 T 01-11-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFULGI_00025940 fa97ca4007ec488c73c5cf818bbbb1fb 453 Gene3D G3DSA:3.40.640.10 38 292 2.4E-100 T 01-11-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFULGI_00020240 ba994f461d2f86e7eb60349fd368ff4b 384 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 67 78 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFULGI_00020240 ba994f461d2f86e7eb60349fd368ff4b 384 SUPERFAMILY SSF46548 20 96 2.44E-14 T 01-11-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 AFULGI_00020240 ba994f461d2f86e7eb60349fd368ff4b 384 Gene3D G3DSA:1.10.1060.10 5 100 9.9E-7 T 01-11-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 AFULGI_00020240 ba994f461d2f86e7eb60349fd368ff4b 384 Pfam PF02754 Cysteine-rich domain 148 233 6.9E-17 T 01-11-2018 IPR004017 Cysteine-rich domain AFULGI_00020240 ba994f461d2f86e7eb60349fd368ff4b 384 Pfam PF02754 Cysteine-rich domain 267 354 5.4E-17 T 01-11-2018 IPR004017 Cysteine-rich domain AFULGI_00020240 ba994f461d2f86e7eb60349fd368ff4b 384 Pfam PF13534 4Fe-4S dicluster domain 22 81 1.7E-7 T 01-11-2018 AFULGI_00020240 ba994f461d2f86e7eb60349fd368ff4b 384 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 23 34 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFULGI_00021830 16f5963090150f04d6df16f12cbf8d63 254 SUPERFAMILY SSF52166 3 251 3.14E-73 T 01-11-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 AFULGI_00021830 16f5963090150f04d6df16f12cbf8d63 254 Pfam PF00573 Ribosomal protein L4/L1 family 18 251 7.2E-54 T 01-11-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 AFULGI_00021830 16f5963090150f04d6df16f12cbf8d63 254 Hamap MF_01328_A 50S ribosomal protein L4 [rplD]. 4 252 43.792 T 01-11-2018 IPR019970 Ribosomal protein L4 GO:0003735|GO:0005840|GO:0006412|GO:0019843 AFULGI_00021830 16f5963090150f04d6df16f12cbf8d63 254 ProSitePatterns PS00939 Ribosomal protein L1e signature. 107 133 - T 01-11-2018 IPR013000 Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00021830 16f5963090150f04d6df16f12cbf8d63 254 TIGRFAM TIGR03672 rpl4p_arch: 50S ribosomal protein uL4 3 251 3.4E-116 T 01-11-2018 IPR019970 Ribosomal protein L4 GO:0003735|GO:0005840|GO:0006412|GO:0019843 AFULGI_00021830 16f5963090150f04d6df16f12cbf8d63 254 Gene3D G3DSA:3.40.1370.10 3 253 9.5E-98 T 01-11-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 AFULGI_00020170 0ae6591a41193b45f6803f85da60d6e3 595 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 282 401 2.1E-13 T 01-11-2018 IPR000014 PAS domain AFULGI_00020170 0ae6591a41193b45f6803f85da60d6e3 595 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 405 520 1.1E-18 T 01-11-2018 IPR000014 PAS domain AFULGI_00020170 0ae6591a41193b45f6803f85da60d6e3 595 SUPERFAMILY SSF53850 24 240 4.35E-34 T 01-11-2018 AFULGI_00020170 0ae6591a41193b45f6803f85da60d6e3 595 SUPERFAMILY SSF55785 391 516 9.77E-25 T 01-11-2018 IPR035965 PAS domain superfamily AFULGI_00020170 0ae6591a41193b45f6803f85da60d6e3 595 SMART SM00062 23 241 5.8E-46 T 01-11-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF AFULGI_00020170 0ae6591a41193b45f6803f85da60d6e3 595 Gene3D G3DSA:3.30.450.20 406 520 4.2E-21 T 01-11-2018 AFULGI_00020170 0ae6591a41193b45f6803f85da60d6e3 595 Pfam PF08448 PAS fold 292 396 1.0E-8 T 01-11-2018 IPR013656 PAS fold-4 AFULGI_00020170 0ae6591a41193b45f6803f85da60d6e3 595 Pfam PF08448 PAS fold 412 519 1.6E-13 T 01-11-2018 IPR013656 PAS fold-4 AFULGI_00020170 0ae6591a41193b45f6803f85da60d6e3 595 Gene3D G3DSA:3.30.450.20 275 405 4.9E-23 T 01-11-2018 AFULGI_00020170 0ae6591a41193b45f6803f85da60d6e3 595 SUPERFAMILY SSF55785 277 392 1.47E-16 T 01-11-2018 IPR035965 PAS domain superfamily AFULGI_00020170 0ae6591a41193b45f6803f85da60d6e3 595 SMART SM00388 527 586 1.9E-5 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFULGI_00020170 0ae6591a41193b45f6803f85da60d6e3 595 Gene3D G3DSA:3.40.190.10 30 226 4.9E-29 T 01-11-2018 AFULGI_00020170 0ae6591a41193b45f6803f85da60d6e3 595 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 24 239 1.5E-27 T 01-11-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF AFULGI_00020170 0ae6591a41193b45f6803f85da60d6e3 595 Gene3D G3DSA:3.40.190.10 106 199 4.9E-29 T 01-11-2018 AFULGI_00020170 0ae6591a41193b45f6803f85da60d6e3 595 SMART SM00091 286 348 5.5E-4 T 01-11-2018 IPR000014 PAS domain AFULGI_00020170 0ae6591a41193b45f6803f85da60d6e3 595 SMART SM00091 406 470 4.9E-6 T 01-11-2018 IPR000014 PAS domain AFULGI_00020170 0ae6591a41193b45f6803f85da60d6e3 595 SMART SM00086 477 518 4.2E-4 T 01-11-2018 IPR001610 PAC motif AFULGI_00007530 350c1248a614e71add2003cc9ca08b62 130 SMART SM00422 7 75 2.5E-31 T 01-11-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFULGI_00007530 350c1248a614e71add2003cc9ca08b62 130 Gene3D G3DSA:1.10.1660.10 1 127 1.8E-31 T 01-11-2018 AFULGI_00007530 350c1248a614e71add2003cc9ca08b62 130 SUPERFAMILY SSF46955 7 117 9.16E-29 T 01-11-2018 IPR009061 Putative DNA-binding domain superfamily AFULGI_00007530 350c1248a614e71add2003cc9ca08b62 130 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 19 32 1.6E-6 T 01-11-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFULGI_00007530 350c1248a614e71add2003cc9ca08b62 130 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 42 62 1.6E-6 T 01-11-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFULGI_00007530 350c1248a614e71add2003cc9ca08b62 130 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 8 19 1.6E-6 T 01-11-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFULGI_00007530 350c1248a614e71add2003cc9ca08b62 130 Pfam PF13411 MerR HTH family regulatory protein 7 73 9.2E-20 T 01-11-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFULGI_00013620 48f4ca2f25d4c6bdf47536a9fd0c6703 369 Gene3D G3DSA:3.30.70.20 265 353 1.3E-13 T 01-11-2018 AFULGI_00013620 48f4ca2f25d4c6bdf47536a9fd0c6703 369 SUPERFAMILY SSF54862 278 347 1.16E-17 T 01-11-2018 AFULGI_00013620 48f4ca2f25d4c6bdf47536a9fd0c6703 369 Pfam PF14697 4Fe-4S dicluster domain 283 337 4.3E-10 T 01-11-2018 AFULGI_00013620 48f4ca2f25d4c6bdf47536a9fd0c6703 369 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 321 332 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFULGI_00015360 cc4fa40bc80e5c3e2671842bba928cc4 225 TIGRFAM TIGR00035 asp_race: aspartate racemase 1 225 1.2E-102 T 01-11-2018 IPR004380 Aspartate racemase GO:0006520|GO:0016855 AFULGI_00015360 cc4fa40bc80e5c3e2671842bba928cc4 225 SUPERFAMILY SSF53681 102 205 4.09E-30 T 01-11-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AFULGI_00015360 cc4fa40bc80e5c3e2671842bba928cc4 225 Gene3D G3DSA:3.40.50.1860 102 209 1.4E-81 T 01-11-2018 AFULGI_00015360 cc4fa40bc80e5c3e2671842bba928cc4 225 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 191 201 - T 01-11-2018 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AFULGI_00015360 cc4fa40bc80e5c3e2671842bba928cc4 225 SUPERFAMILY SSF53681 1 114 7.85E-33 T 01-11-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AFULGI_00015360 cc4fa40bc80e5c3e2671842bba928cc4 225 Gene3D G3DSA:3.40.50.1860 2 218 1.4E-81 T 01-11-2018 AFULGI_00015360 cc4fa40bc80e5c3e2671842bba928cc4 225 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 77 86 - T 01-11-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AFULGI_00015360 cc4fa40bc80e5c3e2671842bba928cc4 225 Pfam PF01177 Asp/Glu/Hydantoin racemase 5 218 2.3E-58 T 01-11-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AFULGI_00010880 6af73e51366a03b124b7d722c57f67c3 185 Pfam PF01966 HD domain 7 100 1.7E-18 T 01-11-2018 IPR006674 HD domain AFULGI_00010880 6af73e51366a03b124b7d722c57f67c3 185 SMART SM00471 1 110 3.6E-10 T 01-11-2018 IPR003607 HD/PDEase domain AFULGI_00010880 6af73e51366a03b124b7d722c57f67c3 185 SUPERFAMILY SSF109604 2 166 5.14E-55 T 01-11-2018 AFULGI_00010880 6af73e51366a03b124b7d722c57f67c3 185 Gene3D G3DSA:1.10.3210.50 1 183 1.7E-58 T 01-11-2018 AFULGI_00012650 96363a85ddcb060301ebccdd6ff28b15 581 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 426 435 - T 01-11-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 AFULGI_00012650 96363a85ddcb060301ebccdd6ff28b15 581 SUPERFAMILY SSF52540 180 440 4.38E-85 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00012650 96363a85ddcb060301ebccdd6ff28b15 581 Hamap MF_00309 V-type ATP synthase alpha chain [atpA]. 7 581 52.933 T 01-11-2018 IPR022878 V-type ATP synthase catalytic alpha chain GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 AFULGI_00012650 96363a85ddcb060301ebccdd6ff28b15 581 SUPERFAMILY SSF47917 447 535 1.28E-23 T 01-11-2018 AFULGI_00012650 96363a85ddcb060301ebccdd6ff28b15 581 SUPERFAMILY SSF50615 8 75 7.06E-10 T 01-11-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 AFULGI_00012650 96363a85ddcb060301ebccdd6ff28b15 581 Gene3D G3DSA:3.40.50.300 78 435 3.5E-180 T 01-11-2018 AFULGI_00012650 96363a85ddcb060301ebccdd6ff28b15 581 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 214 435 6.8E-95 T 01-11-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 AFULGI_00012650 96363a85ddcb060301ebccdd6ff28b15 581 TIGRFAM TIGR01043 ATP_syn_A_arch: ATP synthase archaeal, A subunit 9 578 0.0 T 01-11-2018 IPR005726 ATP synthase alpha chain, archaea GO:0015986|GO:0033178|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 AFULGI_00012650 96363a85ddcb060301ebccdd6ff28b15 581 Gene3D G3DSA:2.40.30.20 2 76 1.9E-25 T 01-11-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 AFULGI_00012650 96363a85ddcb060301ebccdd6ff28b15 581 Pfam PF16886 ATPsynthase alpha/beta subunit N-term extension 89 205 8.4E-42 T 01-11-2018 IPR031686 ATPsynthase alpha/beta subunit, N-terminal extension KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 AFULGI_00012650 96363a85ddcb060301ebccdd6ff28b15 581 Gene3D G3DSA:1.10.1140.10 436 580 2.6E-46 T 01-11-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 AFULGI_00012650 96363a85ddcb060301ebccdd6ff28b15 581 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 12 73 4.1E-14 T 01-11-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 AFULGI_00012650 96363a85ddcb060301ebccdd6ff28b15 581 Gene3D G3DSA:2.40.50.100 120 187 3.5E-180 T 01-11-2018 AFULGI_00012910 fabff38f3d4ef9f2c5258001082c031d 664 Gene3D G3DSA:3.30.470.20 3 203 1.1E-72 T 01-11-2018 AFULGI_00012910 fabff38f3d4ef9f2c5258001082c031d 664 Gene3D G3DSA:3.40.50.720 215 345 2.2E-47 T 01-11-2018 AFULGI_00012910 fabff38f3d4ef9f2c5258001082c031d 664 SUPERFAMILY SSF51735 213 352 2.96E-40 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily AFULGI_00012910 fabff38f3d4ef9f2c5258001082c031d 664 Gene3D G3DSA:3.30.1490.20 21 91 1.1E-72 T 01-11-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 AFULGI_00012910 fabff38f3d4ef9f2c5258001082c031d 664 SUPERFAMILY SSF56059 1 208 1.24E-42 T 01-11-2018 AFULGI_00012910 fabff38f3d4ef9f2c5258001082c031d 664 SMART SM00881 221 316 2.2E-39 T 01-11-2018 IPR003781 CoA-binding GO:0048037 AFULGI_00012910 fabff38f3d4ef9f2c5258001082c031d 664 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 368 501 4.6E-44 T 01-11-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain AFULGI_00012910 fabff38f3d4ef9f2c5258001082c031d 664 Gene3D G3DSA:3.40.50.261 505 664 1.3E-36 T 01-11-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AFULGI_00012910 fabff38f3d4ef9f2c5258001082c031d 664 Pfam PF13380 CoA binding domain 225 349 3.9E-26 T 01-11-2018 IPR003781 CoA-binding GO:0048037 AFULGI_00012910 fabff38f3d4ef9f2c5258001082c031d 664 SUPERFAMILY SSF52210 347 502 6.54E-33 T 01-11-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AFULGI_00012910 fabff38f3d4ef9f2c5258001082c031d 664 Pfam PF13549 ATP-grasp domain 2 205 1.4E-63 T 01-11-2018 AFULGI_00012910 fabff38f3d4ef9f2c5258001082c031d 664 SUPERFAMILY SSF52210 507 658 1.31E-27 T 01-11-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AFULGI_00012910 fabff38f3d4ef9f2c5258001082c031d 664 Gene3D G3DSA:3.40.50.261 346 504 6.5E-46 T 01-11-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AFULGI_00008260 d8d4c6198e9a6b1fee05c1b7a594a617 299 Gene3D G3DSA:3.20.20.70 3 296 1.1E-76 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFULGI_00008260 d8d4c6198e9a6b1fee05c1b7a594a617 299 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 236 256 - T 01-11-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 AFULGI_00008260 d8d4c6198e9a6b1fee05c1b7a594a617 299 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 39 58 - T 01-11-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 AFULGI_00008260 d8d4c6198e9a6b1fee05c1b7a594a617 299 PIRSF PIRSF000164 1 299 1.0E-80 T 01-11-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 AFULGI_00008260 d8d4c6198e9a6b1fee05c1b7a594a617 299 Hamap MF_00224 Dihydroorotate dehydrogenase [pyrD]. 4 297 33.891 T 01-11-2018 IPR024920 Dihydroorotate dehydrogenase, class 1 GO:0004152|GO:0005737|GO:0006221 AFULGI_00008260 d8d4c6198e9a6b1fee05c1b7a594a617 299 Pfam PF01180 Dihydroorotate dehydrogenase 4 278 6.9E-60 T 01-11-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 AFULGI_00008260 d8d4c6198e9a6b1fee05c1b7a594a617 299 SUPERFAMILY SSF51395 3 297 1.28E-66 T 01-11-2018 AFULGI_00008260 d8d4c6198e9a6b1fee05c1b7a594a617 299 TIGRFAM TIGR01037 pyrD_sub1_fam: dihydroorotate dehydrogenase family protein 4 298 7.5E-139 T 01-11-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 AFULGI_00007190 a01c1edc713043ec5d7719a58c78db6c 231 Gene3D G3DSA:3.40.50.300 1 229 1.9E-65 T 01-11-2018 AFULGI_00007190 a01c1edc713043ec5d7719a58c78db6c 231 ProSitePatterns PS00211 ABC transporters family signature. 121 135 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFULGI_00007190 a01c1edc713043ec5d7719a58c78db6c 231 Pfam PF00005 ABC transporter 18 149 1.9E-29 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFULGI_00007190 a01c1edc713043ec5d7719a58c78db6c 231 SUPERFAMILY SSF52540 3 223 1.5E-66 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00007190 a01c1edc713043ec5d7719a58c78db6c 231 SMART SM00382 27 197 8.1E-20 T 01-11-2018 IPR003593 AAA+ ATPase domain AFULGI_00022050 93250be34a3ab6ced55bde1778e1e90c 1088 SUPERFAMILY SSF54001 590 815 1.33E-44 T 01-11-2018 IPR038765 Papain-like cysteine peptidase superfamily AFULGI_00022050 93250be34a3ab6ced55bde1778e1e90c 1088 ProSitePatterns PS00139 Eukaryotic thiol (cysteine) proteases cysteine active site. 612 623 - T 01-11-2018 IPR000169 Cysteine peptidase, cysteine active site AFULGI_00022050 93250be34a3ab6ced55bde1778e1e90c 1088 SUPERFAMILY SSF69318 819 1075 8.37E-31 T 01-11-2018 AFULGI_00022050 93250be34a3ab6ced55bde1778e1e90c 1088 Pfam PF00112 Papain family cysteine protease 594 813 3.8E-37 T 01-11-2018 IPR000668 Peptidase C1A, papain C-terminal GO:0006508|GO:0008234 AFULGI_00022050 93250be34a3ab6ced55bde1778e1e90c 1088 Gene3D G3DSA:2.60.40.10 350 452 1.0E-10 T 01-11-2018 IPR013783 Immunoglobulin-like fold AFULGI_00022050 93250be34a3ab6ced55bde1778e1e90c 1088 SMART SM00645 594 815 2.4E-29 T 01-11-2018 IPR000668 Peptidase C1A, papain C-terminal GO:0006508|GO:0008234 AFULGI_00022050 93250be34a3ab6ced55bde1778e1e90c 1088 Gene3D G3DSA:2.60.40.10 453 564 1.2E-15 T 01-11-2018 IPR013783 Immunoglobulin-like fold AFULGI_00022050 93250be34a3ab6ced55bde1778e1e90c 1088 Gene3D G3DSA:2.60.40.10 232 346 1.1E-17 T 01-11-2018 IPR013783 Immunoglobulin-like fold AFULGI_00022050 93250be34a3ab6ced55bde1778e1e90c 1088 Pfam PF07705 CARDB 351 447 7.6E-16 T 01-11-2018 IPR011635 CARDB domain AFULGI_00022050 93250be34a3ab6ced55bde1778e1e90c 1088 Pfam PF07705 CARDB 459 556 7.7E-20 T 01-11-2018 IPR011635 CARDB domain AFULGI_00022050 93250be34a3ab6ced55bde1778e1e90c 1088 Pfam PF07705 CARDB 235 338 1.5E-21 T 01-11-2018 IPR011635 CARDB domain AFULGI_00022050 93250be34a3ab6ced55bde1778e1e90c 1088 Gene3D G3DSA:3.90.70.10 585 815 1.7E-48 T 01-11-2018 AFULGI_00022050 93250be34a3ab6ced55bde1778e1e90c 1088 PRINTS PR00705 Papain cysteine protease (C1) family signature 771 777 2.7E-5 T 01-11-2018 IPR000668 Peptidase C1A, papain C-terminal GO:0006508|GO:0008234 AFULGI_00022050 93250be34a3ab6ced55bde1778e1e90c 1088 PRINTS PR00705 Papain cysteine protease (C1) family signature 748 758 2.7E-5 T 01-11-2018 IPR000668 Peptidase C1A, papain C-terminal GO:0006508|GO:0008234 AFULGI_00022050 93250be34a3ab6ced55bde1778e1e90c 1088 PRINTS PR00705 Papain cysteine protease (C1) family signature 612 627 2.7E-5 T 01-11-2018 IPR000668 Peptidase C1A, papain C-terminal GO:0006508|GO:0008234 AFULGI_00014520 2935a9c70112f2f6f5ba5164479e6c06 372 SUPERFAMILY SSF48256 3 372 7.72E-129 T 01-11-2018 IPR036969 Citrate synthase superfamily GO:0046912 AFULGI_00014520 2935a9c70112f2f6f5ba5164479e6c06 372 Gene3D G3DSA:1.10.230.10 221 319 4.0E-125 T 01-11-2018 IPR016143 Citrate synthase-like, small alpha subdomain AFULGI_00014520 2935a9c70112f2f6f5ba5164479e6c06 372 Gene3D G3DSA:1.10.580.10 27 352 4.0E-125 T 01-11-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 AFULGI_00014520 2935a9c70112f2f6f5ba5164479e6c06 372 Pfam PF00285 Citrate synthase, C-terminal domain 4 355 1.1E-124 T 01-11-2018 IPR002020 Citrate synthase GO:0046912 AFULGI_00014520 2935a9c70112f2f6f5ba5164479e6c06 372 PIRSF PIRSF001369 1 372 1.0E-137 T 01-11-2018 IPR024176 Citrate synthase, bacterial-type AFULGI_00014520 2935a9c70112f2f6f5ba5164479e6c06 372 TIGRFAM TIGR01800 cit_synth_II: 2-methylcitrate synthase/citrate synthase II 3 372 4.4E-171 T 01-11-2018 IPR011278 2-methylcitrate synthase/citrate synthase type I GO:0005737|GO:0046912 AFULGI_00014520 2935a9c70112f2f6f5ba5164479e6c06 372 PRINTS PR00143 Citrate synthase signature 325 339 2.0E-38 T 01-11-2018 IPR002020 Citrate synthase GO:0046912 AFULGI_00014520 2935a9c70112f2f6f5ba5164479e6c06 372 PRINTS PR00143 Citrate synthase signature 195 223 2.0E-38 T 01-11-2018 IPR002020 Citrate synthase GO:0046912 AFULGI_00014520 2935a9c70112f2f6f5ba5164479e6c06 372 PRINTS PR00143 Citrate synthase signature 124 137 2.0E-38 T 01-11-2018 IPR002020 Citrate synthase GO:0046912 AFULGI_00014520 2935a9c70112f2f6f5ba5164479e6c06 372 PRINTS PR00143 Citrate synthase signature 173 188 2.0E-38 T 01-11-2018 IPR002020 Citrate synthase GO:0046912 AFULGI_00014520 2935a9c70112f2f6f5ba5164479e6c06 372 PRINTS PR00143 Citrate synthase signature 248 268 2.0E-38 T 01-11-2018 IPR002020 Citrate synthase GO:0046912 AFULGI_00014520 2935a9c70112f2f6f5ba5164479e6c06 372 PRINTS PR00143 Citrate synthase signature 305 321 2.0E-38 T 01-11-2018 IPR002020 Citrate synthase GO:0046912 AFULGI_00022330 c8644283d35724abf63d736d46393deb 329 Gene3D G3DSA:3.30.300.110 62 140 3.1E-16 T 01-11-2018 AFULGI_00022330 c8644283d35724abf63d736d46393deb 329 Hamap MF_01922 tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase [taw2]. 81 329 43.582 T 01-11-2018 IPR030867 tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase GO:0006400|GO:0016765 MetaCyc: PWY-7286 AFULGI_00022330 c8644283d35724abf63d736d46393deb 329 Pfam PF02475 Met-10+ like-protein 84 277 1.8E-78 T 01-11-2018 IPR030382 SAM-dependent methyltransferase TRM5/TYW2-type Reactome: R-HSA-6782861 AFULGI_00022330 c8644283d35724abf63d736d46393deb 329 Gene3D G3DSA:3.40.50.150 143 329 4.9E-57 T 01-11-2018 AFULGI_00022330 c8644283d35724abf63d736d46393deb 329 SUPERFAMILY SSF53335 79 328 9.25E-66 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFULGI_00011380 cb9ca0ac4353c940c2b86bbc22222468 121 SUPERFAMILY SSF52172 1 118 7.83E-38 T 01-11-2018 IPR011006 CheY-like superfamily AFULGI_00011380 cb9ca0ac4353c940c2b86bbc22222468 121 SMART SM00448 2 114 8.1E-37 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFULGI_00011380 cb9ca0ac4353c940c2b86bbc22222468 121 Pfam PF00072 Response regulator receiver domain 4 114 1.1E-32 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFULGI_00011380 cb9ca0ac4353c940c2b86bbc22222468 121 Gene3D G3DSA:3.40.50.12740 3 121 4.2E-38 T 01-11-2018 AFULGI_00021880 b25cc0aaf32fafce4ba1ba9f9533db63 421 Gene3D G3DSA:3.40.50.740 53 105 3.1E-19 T 01-11-2018 AFULGI_00021880 b25cc0aaf32fafce4ba1ba9f9533db63 421 SUPERFAMILY SSF53706 4 419 8.9E-68 T 01-11-2018 AFULGI_00021880 b25cc0aaf32fafce4ba1ba9f9533db63 421 PIRSF PIRSF005646 1 421 1.7E-191 T 01-11-2018 IPR016457 Formylmethanofuran dehydrogenase, subunit B GO:0015948|GO:0018493 KEGG: 00680+1.2.7.12|MetaCyc: PWY-5209|MetaCyc: PWY-7784 AFULGI_00021880 b25cc0aaf32fafce4ba1ba9f9533db63 421 Gene3D G3DSA:3.40.228.10 217 287 1.9E-11 T 01-11-2018 AFULGI_00021880 b25cc0aaf32fafce4ba1ba9f9533db63 421 Gene3D G3DSA:3.40.50.740 288 413 1.9E-11 T 01-11-2018 AFULGI_00021880 b25cc0aaf32fafce4ba1ba9f9533db63 421 Pfam PF00384 Molybdopterin oxidoreductase 44 402 2.7E-11 T 01-11-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFULGI_00021880 b25cc0aaf32fafce4ba1ba9f9533db63 421 TIGRFAM TIGR03129 one_C_dehyd_B: formylmethanofuran dehydrogenase subunit B 6 416 4.2E-180 T 01-11-2018 IPR016457 Formylmethanofuran dehydrogenase, subunit B GO:0015948|GO:0018493 KEGG: 00680+1.2.7.12|MetaCyc: PWY-5209|MetaCyc: PWY-7784 AFULGI_00021880 b25cc0aaf32fafce4ba1ba9f9533db63 421 Gene3D G3DSA:3.40.228.10 106 205 3.1E-19 T 01-11-2018 AFULGI_00008460 7230d0bd211cebb2c2fcae669cadbca7 71 ProSitePatterns PS00961 Ribosomal protein S28e signature. 60 68 - T 01-11-2018 IPR028626 Ribosomal protein S28e conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00008460 7230d0bd211cebb2c2fcae669cadbca7 71 Gene3D G3DSA:2.40.50.140 4 70 1.5E-28 T 01-11-2018 AFULGI_00008460 7230d0bd211cebb2c2fcae669cadbca7 71 Pfam PF01200 Ribosomal protein S28e 5 68 2.1E-30 T 01-11-2018 IPR000289 Ribosomal protein S28e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00008460 7230d0bd211cebb2c2fcae669cadbca7 71 SUPERFAMILY SSF50249 4 69 3.68E-25 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold AFULGI_00008460 7230d0bd211cebb2c2fcae669cadbca7 71 Hamap MF_00292 30S ribosomal protein S28e [rps28e]. 1 69 25.085 T 01-11-2018 IPR000289 Ribosomal protein S28e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00008460 7230d0bd211cebb2c2fcae669cadbca7 71 ProDom PD005541 RIBOSOMAL RIBONUCLEOPROTEIN 40S S28 S28E 30S ACETYLATION S33 S33 CG15527 7 51 1.0E-18 T 01-11-2018 IPR000289 Ribosomal protein S28e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00010470 14efce871196650443fa68c57e3a6109 489 TIGRFAM TIGR02090 LEU1_arch: isopropylmalate/citramalate/homocitrate synthases 3 366 3.4E-188 T 01-11-2018 IPR011830 Isopropylmalate/citramalate/homocitrate synthase GO:0019752|GO:0046912 AFULGI_00010470 14efce871196650443fa68c57e3a6109 489 SUPERFAMILY SSF110921 378 488 5.23E-23 T 01-11-2018 IPR036230 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain superfamily KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 AFULGI_00010470 14efce871196650443fa68c57e3a6109 489 Gene3D G3DSA:1.10.238.260 268 382 6.6E-35 T 01-11-2018 AFULGI_00010470 14efce871196650443fa68c57e3a6109 489 Gene3D G3DSA:3.30.160.270 383 488 1.1E-7 T 01-11-2018 AFULGI_00010470 14efce871196650443fa68c57e3a6109 489 SMART SM00917 356 489 1.2E-34 T 01-11-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 AFULGI_00010470 14efce871196650443fa68c57e3a6109 489 Gene3D G3DSA:3.20.20.70 1 264 7.0E-93 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFULGI_00010470 14efce871196650443fa68c57e3a6109 489 Pfam PF08502 LeuA allosteric (dimerisation) domain 357 488 8.8E-38 T 01-11-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 AFULGI_00010470 14efce871196650443fa68c57e3a6109 489 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 190 203 - T 01-11-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 AFULGI_00010470 14efce871196650443fa68c57e3a6109 489 SUPERFAMILY SSF51569 3 279 6.41E-87 T 01-11-2018 AFULGI_00010470 14efce871196650443fa68c57e3a6109 489 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 10 26 - T 01-11-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 AFULGI_00010470 14efce871196650443fa68c57e3a6109 489 Pfam PF00682 HMGL-like 2 261 1.3E-83 T 01-11-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 AFULGI_00010470 14efce871196650443fa68c57e3a6109 489 Hamap MF_01028 Putative (R)-citramalate synthase CimA [cimA]. 10 489 80.173 T 01-11-2018 IPR024890 (R)-citramalate synthase CimA GO:0043714 KEGG: 00290+2.3.1.182|KEGG: 00660+2.3.1.182|MetaCyc: PWY-5101 AFULGI_00006240 df3b9eaf188cedec66e39eb6d201063e 313 TIGRFAM TIGR00287 cas1: CRISPR-associated endonuclease Cas1 3 309 1.5E-71 T 01-11-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 AFULGI_00006240 df3b9eaf188cedec66e39eb6d201063e 313 Gene3D G3DSA:1.20.120.920 82 313 1.3E-57 T 01-11-2018 AFULGI_00006240 df3b9eaf188cedec66e39eb6d201063e 313 Gene3D G3DSA:3.100.10.20 1 79 3.7E-16 T 01-11-2018 AFULGI_00006240 df3b9eaf188cedec66e39eb6d201063e 313 Hamap MF_01470 CRISPR-associated endonuclease Cas1 [cas1]. 1 299 23.165 T 01-11-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 AFULGI_00006240 df3b9eaf188cedec66e39eb6d201063e 313 Pfam PF01867 CRISPR associated protein Cas1 4 248 3.3E-63 T 01-11-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 AFULGI_00017490 c3748b5e412b549298d1a8d37c539f32 416 SUPERFAMILY SSF55205 3 411 4.25E-101 T 01-11-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 AFULGI_00017490 c3748b5e412b549298d1a8d37c539f32 416 PIRSF PIRSF000505 1 415 1.7E-140 T 01-11-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 AFULGI_00017490 c3748b5e412b549298d1a8d37c539f32 416 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 8 412 33.503 T 01-11-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 AFULGI_00017490 c3748b5e412b549298d1a8d37c539f32 416 Gene3D G3DSA:3.65.10.10 20 226 2.3E-118 T 01-11-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 AFULGI_00017490 c3748b5e412b549298d1a8d37c539f32 416 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 12 411 7.8E-123 T 01-11-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 AFULGI_00017490 c3748b5e412b549298d1a8d37c539f32 416 Gene3D G3DSA:3.65.10.10 12 403 2.3E-118 T 01-11-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 AFULGI_00017490 c3748b5e412b549298d1a8d37c539f32 416 ProSitePatterns PS00104 EPSP synthase signature 1. 82 96 - T 01-11-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 AFULGI_00017490 c3748b5e412b549298d1a8d37c539f32 416 ProSitePatterns PS00885 EPSP synthase signature 2. 325 343 - T 01-11-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 AFULGI_00017490 c3748b5e412b549298d1a8d37c539f32 416 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 8 406 1.1E-94 T 01-11-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 AFULGI_00002110 b1016633f3bf303e7b820445b8c794f2 312 Pfam PF02653 Branched-chain amino acid transport system / permease component 27 294 9.2E-50 T 01-11-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 AFULGI_00014360 e2a4ff97e684355bce43a1c904424085 371 Gene3D G3DSA:1.20.1250.20 191 367 2.1E-23 T 01-11-2018 AFULGI_00014360 e2a4ff97e684355bce43a1c904424085 371 Pfam PF07690 Major Facilitator Superfamily 4 186 7.4E-32 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFULGI_00014360 e2a4ff97e684355bce43a1c904424085 371 Pfam PF07690 Major Facilitator Superfamily 198 354 1.3E-22 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFULGI_00014360 e2a4ff97e684355bce43a1c904424085 371 SUPERFAMILY SSF103473 2 359 9.16E-56 T 01-11-2018 IPR036259 MFS transporter superfamily AFULGI_00014360 e2a4ff97e684355bce43a1c904424085 371 Gene3D G3DSA:1.20.1250.20 1 190 3.9E-33 T 01-11-2018 AFULGI_00003910 2cd6707b69d837005d56d89cce821b42 355 TIGRFAM TIGR00423 TIGR00423: radical SAM domain protein, CofH subfamily 49 352 2.9E-140 T 01-11-2018 IPR020050 FO synthase, subunit 2 GO:0016765 KEGG: 00680+2.5.1.77 AFULGI_00003910 2cd6707b69d837005d56d89cce821b42 355 Gene3D G3DSA:3.20.20.70 2 346 4.5E-65 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFULGI_00003910 2cd6707b69d837005d56d89cce821b42 355 TIGRFAM TIGR03699 menaquin_MqnC: dehypoxanthine futalosine cyclase 15 352 4.0E-153 T 01-11-2018 IPR022431 Cyclic dehypoxanthine futalosine synthase GO:0009234 KEGG: 00130+1.21.98.1|MetaCyc: PWY-7371|MetaCyc: PWY-7374 AFULGI_00003910 2cd6707b69d837005d56d89cce821b42 355 SUPERFAMILY SSF102114 16 317 2.88E-55 T 01-11-2018 AFULGI_00003910 2cd6707b69d837005d56d89cce821b42 355 Pfam PF04055 Radical SAM superfamily 57 225 2.0E-20 T 01-11-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFULGI_00003910 2cd6707b69d837005d56d89cce821b42 355 Hamap MF_00992 Cyclic dehypoxanthine futalosine synthase [mqnC]. 14 355 52.258 T 01-11-2018 IPR022431 Cyclic dehypoxanthine futalosine synthase GO:0009234 KEGG: 00130+1.21.98.1|MetaCyc: PWY-7371|MetaCyc: PWY-7374 AFULGI_00003910 2cd6707b69d837005d56d89cce821b42 355 PIRSF PIRSF004762 7 355 5.3E-110 T 01-11-2018 AFULGI_00026270 8ba323f755819e19d96cbdf7645c24ae 269 TIGRFAM TIGR00507 aroE: shikimate dehydrogenase 3 267 1.7E-105 T 01-11-2018 IPR011342 Shikimate dehydrogenase GO:0004764|GO:0019632|GO:0050661|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 AFULGI_00026270 8ba323f755819e19d96cbdf7645c24ae 269 SUPERFAMILY SSF51735 98 267 1.82E-46 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily AFULGI_00026270 8ba323f755819e19d96cbdf7645c24ae 269 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 1 265 33.95 T 01-11-2018 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 AFULGI_00026270 8ba323f755819e19d96cbdf7645c24ae 269 SUPERFAMILY SSF53223 2 97 4.09E-25 T 01-11-2018 AFULGI_00026270 8ba323f755819e19d96cbdf7645c24ae 269 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 6 87 2.0E-28 T 01-11-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 AFULGI_00026270 8ba323f755819e19d96cbdf7645c24ae 269 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 110 184 2.9E-9 T 01-11-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase AFULGI_00026270 8ba323f755819e19d96cbdf7645c24ae 269 Gene3D G3DSA:3.40.50.720 97 233 3.6E-81 T 01-11-2018 AFULGI_00026270 8ba323f755819e19d96cbdf7645c24ae 269 Gene3D G3DSA:3.40.50.10860 4 256 3.6E-81 T 01-11-2018 AFULGI_00021790 1d523925126099c8d6c16622c5300a5c 155 Pfam PF00237 Ribosomal protein L22p/L17e 21 151 1.3E-32 T 01-11-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 AFULGI_00021790 1d523925126099c8d6c16622c5300a5c 155 TIGRFAM TIGR01038 uL22_arch_euk: ribosomal protein uL22 8 154 2.0E-71 T 01-11-2018 IPR005721 Ribosomal protein L22/L17, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00021790 1d523925126099c8d6c16622c5300a5c 155 SUPERFAMILY SSF54843 6 152 6.67E-49 T 01-11-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 AFULGI_00021790 1d523925126099c8d6c16622c5300a5c 155 Hamap MF_01331_A 50S ribosomal protein L22 [rplV]. 4 155 35.406 T 01-11-2018 IPR005721 Ribosomal protein L22/L17, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00021790 1d523925126099c8d6c16622c5300a5c 155 Gene3D G3DSA:3.90.470.10 5 155 4.5E-54 T 01-11-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 AFULGI_00019590 20fbcf1aa4907e20c3934711ae9be101 304 SMART SM00748 56 138 0.0051 T 01-11-2018 IPR007842 HEPN domain AFULGI_00019590 20fbcf1aa4907e20c3934711ae9be101 304 Gene3D G3DSA:1.20.120.330 45 191 3.2E-12 T 01-11-2018 AFULGI_00019590 20fbcf1aa4907e20c3934711ae9be101 304 Pfam PF05168 HEPN domain 53 103 1.4E-9 T 01-11-2018 IPR007842 HEPN domain AFULGI_00019590 20fbcf1aa4907e20c3934711ae9be101 304 SUPERFAMILY SSF81593 55 103 2.79E-8 T 01-11-2018 AFULGI_00019120 b9cddf954c4060e53d0adcae5a29b3f1 93 Pfam PF14947 Winged helix-turn-helix 2 79 1.7E-23 T 01-11-2018 IPR038723 ArnR1-like, winged helix-turn-helix domain AFULGI_00019120 b9cddf954c4060e53d0adcae5a29b3f1 93 SUPERFAMILY SSF46785 3 89 1.57E-12 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00019120 b9cddf954c4060e53d0adcae5a29b3f1 93 Gene3D G3DSA:1.10.10.10 1 92 3.3E-27 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00025840 ddad933bcfd5b2469b75004130115458 317 Gene3D G3DSA:1.10.600.10 1 317 1.4E-104 T 01-11-2018 IPR008949 Isoprenoid synthase domain superfamily AFULGI_00025840 ddad933bcfd5b2469b75004130115458 317 SUPERFAMILY SSF48576 6 316 6.91E-89 T 01-11-2018 IPR008949 Isoprenoid synthase domain superfamily AFULGI_00025840 ddad933bcfd5b2469b75004130115458 317 Pfam PF00348 Polyprenyl synthetase 29 246 3.9E-67 T 01-11-2018 IPR000092 Polyprenyl synthetase GO:0008299 AFULGI_00025840 ddad933bcfd5b2469b75004130115458 317 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 78 92 - T 01-11-2018 IPR033749 Polyprenyl synthetase, conserved site AFULGI_00019400 de8093e216a636506006b2d32a9e8f40 267 SUPERFAMILY SSF103481 35 132 1.09E-11 T 01-11-2018 AFULGI_00019400 de8093e216a636506006b2d32a9e8f40 267 Pfam PF00892 EamA-like transporter family 3 128 6.7E-8 T 01-11-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFULGI_00019400 de8093e216a636506006b2d32a9e8f40 267 Pfam PF00892 EamA-like transporter family 137 265 1.2E-13 T 01-11-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFULGI_00019400 de8093e216a636506006b2d32a9e8f40 267 SUPERFAMILY SSF103481 172 264 5.75E-11 T 01-11-2018 AFULGI_00014260 03a7473bf8fc8a27f1cf04061a09cf2c 396 Gene3D G3DSA:3.40.50.1100 99 195 5.7E-132 T 01-11-2018 AFULGI_00014260 03a7473bf8fc8a27f1cf04061a09cf2c 396 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 63 364 1.5E-80 T 01-11-2018 IPR001926 Pyridoxal-phosphate dependent enzyme AFULGI_00014260 03a7473bf8fc8a27f1cf04061a09cf2c 396 PIRSF PIRSF038945 26 396 2.8E-172 T 01-11-2018 IPR026260 Threonine synthase, bacterial/archaeal GO:0004795|GO:0009088 KEGG: 00260+4.2.3.1|KEGG: 00750+4.2.3.1 AFULGI_00014260 03a7473bf8fc8a27f1cf04061a09cf2c 396 TIGRFAM TIGR00260 thrC: threonine synthase 48 371 2.9E-119 T 01-11-2018 IPR004450 Threonine synthase-like AFULGI_00014260 03a7473bf8fc8a27f1cf04061a09cf2c 396 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 90 104 - T 01-11-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 AFULGI_00014260 03a7473bf8fc8a27f1cf04061a09cf2c 396 Gene3D G3DSA:3.40.50.1100 47 374 5.7E-132 T 01-11-2018 AFULGI_00014260 03a7473bf8fc8a27f1cf04061a09cf2c 396 SUPERFAMILY SSF53686 2 383 6.42E-116 T 01-11-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme AFULGI_00003420 2285854d8fd0694333f714564ab78740 191 SUPERFAMILY SSF52218 1 190 1.27E-50 T 01-11-2018 IPR029039 Flavoprotein-like superfamily AFULGI_00003420 2285854d8fd0694333f714564ab78740 191 TIGRFAM TIGR01755 flav_wrbA: NAD(P)H:quinone oxidoreductase, type IV 3 190 5.6E-52 T 01-11-2018 IPR010089 Flavoprotein WrbA-like GO:0003955|GO:0010181 KEGG: 00130+1.6.5.2|MetaCyc: PWY-7731 AFULGI_00003420 2285854d8fd0694333f714564ab78740 191 ProSitePatterns PS00201 Flavodoxin signature. 6 22 - T 01-11-2018 IPR001226 Flavodoxin, conserved site GO:0009055|GO:0010181 AFULGI_00003420 2285854d8fd0694333f714564ab78740 191 Pfam PF03358 NADPH-dependent FMN reductase 3 145 2.7E-14 T 01-11-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 AFULGI_00003420 2285854d8fd0694333f714564ab78740 191 Gene3D G3DSA:3.40.50.360 1 191 2.4E-64 T 01-11-2018 IPR029039 Flavoprotein-like superfamily AFULGI_00026920 f709c436fe9a046447a54d6661f625e4 627 Pfam PF04312 Protein of unknown function (DUF460) 210 342 2.1E-50 T 01-11-2018 IPR007408 Protein of unknown function DUF460 AFULGI_00008820 b1ae9f37ef3e3bf77b74532dd43793c7 178 SUPERFAMILY SSF56300 2 176 1.57E-42 T 01-11-2018 AFULGI_00008820 b1ae9f37ef3e3bf77b74532dd43793c7 178 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 4 160 2.3E-54 T 01-11-2018 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 AFULGI_00008820 b1ae9f37ef3e3bf77b74532dd43793c7 178 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 4 156 1.3E-20 T 01-11-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 AFULGI_00008820 b1ae9f37ef3e3bf77b74532dd43793c7 178 Gene3D G3DSA:3.60.21.10 1 178 9.6E-51 T 01-11-2018 IPR029052 Metallo-dependent phosphatase-like AFULGI_00010850 45ac7e811357acefb8bbefdc0ac148eb 395 Gene3D G3DSA:1.10.540.10 2 130 1.9E-36 T 01-11-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 AFULGI_00010850 45ac7e811357acefb8bbefdc0ac148eb 395 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 15 129 3.5E-32 T 01-11-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 AFULGI_00010850 45ac7e811357acefb8bbefdc0ac148eb 395 SUPERFAMILY SSF56645 4 236 2.88E-75 T 01-11-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 AFULGI_00010850 45ac7e811357acefb8bbefdc0ac148eb 395 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 237 384 1.1E-37 T 01-11-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AFULGI_00010850 45ac7e811357acefb8bbefdc0ac148eb 395 SUPERFAMILY SSF47203 242 388 9.34E-43 T 01-11-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 AFULGI_00010850 45ac7e811357acefb8bbefdc0ac148eb 395 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 133 222 1.0E-21 T 01-11-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 AFULGI_00010850 45ac7e811357acefb8bbefdc0ac148eb 395 Gene3D G3DSA:1.20.140.10 242 395 9.0E-42 T 01-11-2018 AFULGI_00010850 45ac7e811357acefb8bbefdc0ac148eb 395 Gene3D G3DSA:2.40.110.10 132 237 1.3E-35 T 01-11-2018 AFULGI_00025640 be5b53c368a49461c1821c6dc2d58667 174 Gene3D G3DSA:3.40.109.10 1 174 1.0E-54 T 01-11-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 AFULGI_00025640 be5b53c368a49461c1821c6dc2d58667 174 Pfam PF00881 Nitroreductase family 73 150 2.8E-11 T 01-11-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 AFULGI_00025640 be5b53c368a49461c1821c6dc2d58667 174 Pfam PF00881 Nitroreductase family 8 64 2.9E-18 T 01-11-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 AFULGI_00025640 be5b53c368a49461c1821c6dc2d58667 174 PIRSF PIRSF000232 1 174 8.8E-45 T 01-11-2018 IPR026021 Putative NAD(P)H nitroreductase YdjA-like AFULGI_00025640 be5b53c368a49461c1821c6dc2d58667 174 SUPERFAMILY SSF55469 1 172 1.96E-52 T 01-11-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 AFULGI_00010610 4e33e20baf0eb3839bae417e81803577 600 Pfam PF03445 Putative nucleotidyltransferase DUF294 290 421 4.0E-35 T 01-11-2018 IPR005105 Protein-PII uridylyltransferase, N-terminal GO:0008773 AFULGI_00010610 4e33e20baf0eb3839bae417e81803577 600 Gene3D G3DSA:3.10.580.10 137 304 8.5E-30 T 01-11-2018 AFULGI_00010610 4e33e20baf0eb3839bae417e81803577 600 SMART SM00116 152 200 5.1E-5 T 01-11-2018 IPR000644 CBS domain AFULGI_00010610 4e33e20baf0eb3839bae417e81803577 600 SMART SM00116 216 263 5.0E-6 T 01-11-2018 IPR000644 CBS domain AFULGI_00010610 4e33e20baf0eb3839bae417e81803577 600 SUPERFAMILY SSF51206 5 117 2.36E-22 T 01-11-2018 IPR018490 Cyclic nucleotide-binding-like AFULGI_00010610 4e33e20baf0eb3839bae417e81803577 600 Gene3D G3DSA:1.20.120.330 498 596 2.9E-5 T 01-11-2018 AFULGI_00010610 4e33e20baf0eb3839bae417e81803577 600 Pfam PF00571 CBS domain 145 199 6.0E-10 T 01-11-2018 IPR000644 CBS domain AFULGI_00010610 4e33e20baf0eb3839bae417e81803577 600 Pfam PF00571 CBS domain 209 260 1.9E-10 T 01-11-2018 IPR000644 CBS domain AFULGI_00010610 4e33e20baf0eb3839bae417e81803577 600 Pfam PF00027 Cyclic nucleotide-binding domain 33 109 5.0E-11 T 01-11-2018 IPR000595 Cyclic nucleotide-binding domain AFULGI_00010610 4e33e20baf0eb3839bae417e81803577 600 SMART SM00100 13 124 1.3E-8 T 01-11-2018 IPR000595 Cyclic nucleotide-binding domain AFULGI_00010610 4e33e20baf0eb3839bae417e81803577 600 Pfam PF10335 Putative nucleotidyltransferase substrate binding domain 457 594 2.6E-40 T 01-11-2018 IPR018821 Domain of unknown function DUF294, putative nucleotidyltransferase substrate-binding AFULGI_00010610 4e33e20baf0eb3839bae417e81803577 600 Gene3D G3DSA:2.60.120.10 5 124 4.9E-20 T 01-11-2018 IPR014710 RmlC-like jelly roll fold AFULGI_00010610 4e33e20baf0eb3839bae417e81803577 600 SUPERFAMILY SSF54631 143 262 4.67E-29 T 01-11-2018 AFULGI_00019540 6ca518e97742b4c9a4c7493869bbbb4a 299 Pfam PF00665 Integrase core domain 129 245 1.5E-25 T 01-11-2018 IPR001584 Integrase, catalytic core GO:0015074 AFULGI_00019540 6ca518e97742b4c9a4c7493869bbbb4a 299 Pfam PF13518 Helix-turn-helix domain 12 58 9.1E-9 T 01-11-2018 AFULGI_00019540 6ca518e97742b4c9a4c7493869bbbb4a 299 SUPERFAMILY SSF46689 4 109 8.06E-15 T 01-11-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFULGI_00019540 6ca518e97742b4c9a4c7493869bbbb4a 299 SUPERFAMILY SSF53098 125 270 1.01E-28 T 01-11-2018 IPR012337 Ribonuclease H-like superfamily AFULGI_00019540 6ca518e97742b4c9a4c7493869bbbb4a 299 Gene3D G3DSA:3.30.420.10 124 290 8.5E-23 T 01-11-2018 IPR036397 Ribonuclease H superfamily GO:0003676 AFULGI_00022730 6ca518e97742b4c9a4c7493869bbbb4a 299 Pfam PF00665 Integrase core domain 129 245 1.5E-25 T 01-11-2018 IPR001584 Integrase, catalytic core GO:0015074 AFULGI_00022730 6ca518e97742b4c9a4c7493869bbbb4a 299 Pfam PF13518 Helix-turn-helix domain 12 58 9.1E-9 T 01-11-2018 AFULGI_00022730 6ca518e97742b4c9a4c7493869bbbb4a 299 SUPERFAMILY SSF46689 4 109 8.06E-15 T 01-11-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFULGI_00022730 6ca518e97742b4c9a4c7493869bbbb4a 299 SUPERFAMILY SSF53098 125 270 1.01E-28 T 01-11-2018 IPR012337 Ribonuclease H-like superfamily AFULGI_00022730 6ca518e97742b4c9a4c7493869bbbb4a 299 Gene3D G3DSA:3.30.420.10 124 290 8.5E-23 T 01-11-2018 IPR036397 Ribonuclease H superfamily GO:0003676 AFULGI_00009210 a200587713a1dfbe1f05a474501362ed 344 SUPERFAMILY SSF55315 237 342 3.53E-25 T 01-11-2018 IPR029064 50S ribosomal protein L30e-like AFULGI_00009210 a200587713a1dfbe1f05a474501362ed 344 SMART SM01194 1 124 1.1E-41 T 01-11-2018 IPR005140 eRF1 domain 1/Pelota-like AFULGI_00009210 a200587713a1dfbe1f05a474501362ed 344 Hamap MF_01853 Protein pelota homolog [pelA]. 2 342 34.318 T 01-11-2018 IPR023521 Translation release factor pelota, archaea GO:0070481|GO:0070966|GO:0071025 AFULGI_00009210 a200587713a1dfbe1f05a474501362ed 344 Gene3D G3DSA:2.30.30.870 1 128 3.4E-46 T 01-11-2018 IPR038069 Pelota/DOM34, N-terminal domain AFULGI_00009210 a200587713a1dfbe1f05a474501362ed 344 Pfam PF03464 eRF1 domain 2 180 238 2.2E-7 T 01-11-2018 IPR005141 eRF1 domain 2 AFULGI_00009210 a200587713a1dfbe1f05a474501362ed 344 Gene3D G3DSA:3.30.1330.30 246 344 2.4E-37 T 01-11-2018 IPR029064 50S ribosomal protein L30e-like AFULGI_00009210 a200587713a1dfbe1f05a474501362ed 344 SUPERFAMILY SSF53137 127 241 9.59E-24 T 01-11-2018 AFULGI_00009210 a200587713a1dfbe1f05a474501362ed 344 TIGRFAM TIGR00111 pelota: mRNA surveillance protein pelota 1 342 3.2E-149 T 01-11-2018 IPR004405 Translation release factor pelota GO:0070481|GO:0070966|GO:0071025 AFULGI_00009210 a200587713a1dfbe1f05a474501362ed 344 Pfam PF03465 eRF1 domain 3 247 342 9.6E-22 T 01-11-2018 IPR005142 eRF1 domain 3 AFULGI_00009210 a200587713a1dfbe1f05a474501362ed 344 SUPERFAMILY SSF159065 6 123 7.85E-33 T 01-11-2018 IPR038069 Pelota/DOM34, N-terminal domain AFULGI_00009210 a200587713a1dfbe1f05a474501362ed 344 Pfam PF03463 eRF1 domain 1 3 122 4.8E-28 T 01-11-2018 IPR005140 eRF1 domain 1/Pelota-like AFULGI_00009210 a200587713a1dfbe1f05a474501362ed 344 Gene3D G3DSA:3.30.420.60 129 245 8.8E-29 T 01-11-2018 AFULGI_00023370 d54c655de21933793d6eb8be082bc67e 147 Pfam PF01090 Ribosomal protein S19e 3 135 1.2E-55 T 01-11-2018 IPR001266 Ribosomal protein S19e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00023370 d54c655de21933793d6eb8be082bc67e 147 ProSitePatterns PS00628 Ribosomal protein S19e signature. 85 104 - T 01-11-2018 IPR018277 Ribosomal protein S19e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00023370 d54c655de21933793d6eb8be082bc67e 147 Gene3D G3DSA:1.10.10.2700 1 147 1.7E-59 T 01-11-2018 IPR038111 Ribosomal protein S19e domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00023370 d54c655de21933793d6eb8be082bc67e 147 SUPERFAMILY SSF46785 3 147 2.31E-53 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00023370 d54c655de21933793d6eb8be082bc67e 147 SMART SM01413 3 136 1.6E-85 T 01-11-2018 IPR001266 Ribosomal protein S19e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00023370 d54c655de21933793d6eb8be082bc67e 147 Hamap MF_01474 30S ribosomal protein S19e [rps19e]. 1 145 37.499 T 01-11-2018 IPR027548 Ribosomal protein S19e, archaeal GO:0003735|GO:0005840|GO:0006412 AFULGI_00023370 d54c655de21933793d6eb8be082bc67e 147 ProDom PD003854 RIBOSOMAL 40S RIBONUCLEOPROTEIN S19 S19E 30S MULTIGENE FAMILY S19 SSU 3 115 4.0E-61 T 01-11-2018 IPR001266 Ribosomal protein S19e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00019020 0ba04c0b86d6bf0257f0543a8e622a10 1170 Gene3D G3DSA:3.40.50.200 86 261 3.7E-45 T 01-11-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 AFULGI_00019020 0ba04c0b86d6bf0257f0543a8e622a10 1170 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 131 141 - T 01-11-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site AFULGI_00019020 0ba04c0b86d6bf0257f0543a8e622a10 1170 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 167 177 - T 01-11-2018 IPR022398 Peptidase S8, subtilisin, His-active site AFULGI_00019020 0ba04c0b86d6bf0257f0543a8e622a10 1170 SUPERFAMILY SSF52743 51 238 1.22E-44 T 01-11-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 AFULGI_00019020 0ba04c0b86d6bf0257f0543a8e622a10 1170 SMART SM00089 637 719 2.3E-24 T 01-11-2018 IPR022409 PKD/Chitinase domain AFULGI_00019020 0ba04c0b86d6bf0257f0543a8e622a10 1170 SMART SM00089 1091 1165 8.1E-11 T 01-11-2018 IPR022409 PKD/Chitinase domain AFULGI_00019020 0ba04c0b86d6bf0257f0543a8e622a10 1170 Gene3D G3DSA:3.40.50.200 415 631 3.2E-53 T 01-11-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 AFULGI_00019020 0ba04c0b86d6bf0257f0543a8e622a10 1170 SUPERFAMILY SSF49299 1090 1169 8.24E-10 T 01-11-2018 IPR035986 PKD domain superfamily AFULGI_00019020 0ba04c0b86d6bf0257f0543a8e622a10 1170 Pfam PF00082 Subtilase family 473 609 7.8E-37 T 01-11-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 AFULGI_00019020 0ba04c0b86d6bf0257f0543a8e622a10 1170 Pfam PF00082 Subtilase family 126 226 3.1E-20 T 01-11-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 AFULGI_00019020 0ba04c0b86d6bf0257f0543a8e622a10 1170 SUPERFAMILY SSF49299 628 719 1.28E-16 T 01-11-2018 IPR035986 PKD domain superfamily AFULGI_00019020 0ba04c0b86d6bf0257f0543a8e622a10 1170 SUPERFAMILY SSF49464 722 789 4.05E-7 T 01-11-2018 IPR008969 Carboxypeptidase-like, regulatory domain superfamily AFULGI_00019020 0ba04c0b86d6bf0257f0543a8e622a10 1170 Gene3D G3DSA:2.60.40.10 632 718 6.7E-18 T 01-11-2018 IPR013783 Immunoglobulin-like fold AFULGI_00019020 0ba04c0b86d6bf0257f0543a8e622a10 1170 Gene3D G3DSA:2.60.40.10 1083 1170 1.3E-6 T 01-11-2018 IPR013783 Immunoglobulin-like fold AFULGI_00019020 0ba04c0b86d6bf0257f0543a8e622a10 1170 Pfam PF00801 PKD domain 645 708 4.1E-13 T 01-11-2018 IPR000601 PKD domain AFULGI_00019020 0ba04c0b86d6bf0257f0543a8e622a10 1170 SUPERFAMILY SSF52743 466 655 1.7E-52 T 01-11-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 AFULGI_00019020 0ba04c0b86d6bf0257f0543a8e622a10 1170 PRINTS PR00723 Subtilisin serine protease family (S8) signature 563 579 8.5E-11 T 01-11-2018 IPR015500 Peptidase S8, subtilisin-related AFULGI_00019020 0ba04c0b86d6bf0257f0543a8e622a10 1170 PRINTS PR00723 Subtilisin serine protease family (S8) signature 126 145 8.5E-11 T 01-11-2018 IPR015500 Peptidase S8, subtilisin-related AFULGI_00019020 0ba04c0b86d6bf0257f0543a8e622a10 1170 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 564 574 - T 01-11-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site AFULGI_00019020 0ba04c0b86d6bf0257f0543a8e622a10 1170 Gene3D G3DSA:2.60.40.1120 722 790 5.9E-5 T 01-11-2018 AFULGI_00012310 4a31170b4af79c1353d2ed7ade1af68a 399 Pfam PF03952 Enolase, N-terminal domain 3 120 1.2E-31 T 01-11-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFULGI_00012310 4a31170b4af79c1353d2ed7ade1af68a 399 SUPERFAMILY SSF51604 127 394 3.93E-95 T 01-11-2018 IPR036849 Enolase-like, C-terminal domain superfamily AFULGI_00012310 4a31170b4af79c1353d2ed7ade1af68a 399 Gene3D G3DSA:3.30.390.10 1 113 2.5E-29 T 01-11-2018 IPR029017 Enolase-like, N-terminal AFULGI_00012310 4a31170b4af79c1353d2ed7ade1af68a 399 Pfam PF00113 Enolase, C-terminal TIM barrel domain 127 391 1.8E-73 T 01-11-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFULGI_00012310 4a31170b4af79c1353d2ed7ade1af68a 399 SUPERFAMILY SSF54826 3 123 1.61E-34 T 01-11-2018 AFULGI_00012310 4a31170b4af79c1353d2ed7ade1af68a 399 SMART SM01193 3 120 3.3E-43 T 01-11-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFULGI_00012310 4a31170b4af79c1353d2ed7ade1af68a 399 PIRSF PIRSF001400 1 398 3.6E-153 T 01-11-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFULGI_00012310 4a31170b4af79c1353d2ed7ade1af68a 399 SMART SM01192 125 395 4.3E-135 T 01-11-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFULGI_00012310 4a31170b4af79c1353d2ed7ade1af68a 399 ProSitePatterns PS00164 Enolase signature. 315 328 - T 01-11-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFULGI_00012310 4a31170b4af79c1353d2ed7ade1af68a 399 Gene3D G3DSA:3.20.20.120 115 397 5.8E-99 T 01-11-2018 IPR036849 Enolase-like, C-terminal domain superfamily AFULGI_00012310 4a31170b4af79c1353d2ed7ade1af68a 399 PRINTS PR00148 Enolase signature 315 329 1.9E-33 T 01-11-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFULGI_00012310 4a31170b4af79c1353d2ed7ade1af68a 399 PRINTS PR00148 Enolase signature 93 109 1.9E-33 T 01-11-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFULGI_00012310 4a31170b4af79c1353d2ed7ade1af68a 399 PRINTS PR00148 Enolase signature 147 160 1.9E-33 T 01-11-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFULGI_00012310 4a31170b4af79c1353d2ed7ade1af68a 399 PRINTS PR00148 Enolase signature 35 49 1.9E-33 T 01-11-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFULGI_00012310 4a31170b4af79c1353d2ed7ade1af68a 399 PRINTS PR00148 Enolase signature 292 303 1.9E-33 T 01-11-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFULGI_00012310 4a31170b4af79c1353d2ed7ade1af68a 399 PRINTS PR00148 Enolase signature 344 361 1.9E-33 T 01-11-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFULGI_00012310 4a31170b4af79c1353d2ed7ade1af68a 399 Hamap MF_00318 Enolase [eno]. 1 391 38.244 T 01-11-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFULGI_00012310 4a31170b4af79c1353d2ed7ade1af68a 399 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 3 393 4.7E-139 T 01-11-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFULGI_00012130 7e9dee0f0a14669945413927372ca630 62 ProDom PD019197 RNA DNA-DIRECTED POLYMERASE SUBUNIT E'' POLYMERASE RPOE2 TRANSFERASE NUCLEOTIDYLTRANSFERASE E 15 62 8.0E-22 T 01-11-2018 IPR007178 Archaeal transcription elongation factor Spt4 GO:0006355 AFULGI_00012130 7e9dee0f0a14669945413927372ca630 62 Gene3D G3DSA:2.20.28.90 1 62 4.8E-25 T 01-11-2018 IPR038589 Archaeal transcription elongation factor Spt4 superfamily AFULGI_00012130 7e9dee0f0a14669945413927372ca630 62 SUPERFAMILY SSF63393 4 61 1.33E-20 T 01-11-2018 IPR029040 RNA polymerase subunit RPABC4/transcription elongation factor Spt4 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-75955 AFULGI_00012130 7e9dee0f0a14669945413927372ca630 62 SMART SM01389 3 62 1.5E-26 T 01-11-2018 IPR022800 Spt4/RpoE2 zinc finger Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-75955 AFULGI_00012130 7e9dee0f0a14669945413927372ca630 62 Pfam PF06093 Spt4/RpoE2 zinc finger 4 61 1.9E-16 T 01-11-2018 IPR022800 Spt4/RpoE2 zinc finger Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-75955 AFULGI_00012130 7e9dee0f0a14669945413927372ca630 62 Hamap MF_00949 Transcription elongation factor Spt4 [spt4]. 5 62 27.104 T 01-11-2018 IPR007178 Archaeal transcription elongation factor Spt4 GO:0006355 AFULGI_00012840 05c8d4b325db755f94fdf14213f94029 456 Pfam PF13426 PAS domain 146 241 2.8E-12 T 01-11-2018 IPR000014 PAS domain AFULGI_00012840 05c8d4b325db755f94fdf14213f94029 456 SUPERFAMILY SSF55785 18 126 1.42E-19 T 01-11-2018 IPR035965 PAS domain superfamily AFULGI_00012840 05c8d4b325db755f94fdf14213f94029 456 Gene3D G3DSA:3.30.450.20 4 114 2.1E-17 T 01-11-2018 AFULGI_00012840 05c8d4b325db755f94fdf14213f94029 456 Gene3D G3DSA:3.30.450.20 115 240 3.6E-26 T 01-11-2018 AFULGI_00012840 05c8d4b325db755f94fdf14213f94029 456 Gene3D G3DSA:3.30.565.10 316 450 1.0E-31 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFULGI_00012840 05c8d4b325db755f94fdf14213f94029 456 SMART SM00387 350 453 1.1E-25 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFULGI_00012840 05c8d4b325db755f94fdf14213f94029 456 Gene3D G3DSA:1.10.287.130 263 315 1.0E-31 T 01-11-2018 AFULGI_00012840 05c8d4b325db755f94fdf14213f94029 456 SUPERFAMILY SSF55874 318 452 2.23E-26 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFULGI_00012840 05c8d4b325db755f94fdf14213f94029 456 Pfam PF00989 PAS fold 8 114 8.5E-11 T 01-11-2018 IPR013767 PAS fold GO:0006355 AFULGI_00012840 05c8d4b325db755f94fdf14213f94029 456 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 353 451 4.8E-17 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFULGI_00012840 05c8d4b325db755f94fdf14213f94029 456 SMART SM00091 6 73 3.3E-10 T 01-11-2018 IPR000014 PAS domain AFULGI_00012840 05c8d4b325db755f94fdf14213f94029 456 SMART SM00091 129 194 7.8E-10 T 01-11-2018 IPR000014 PAS domain AFULGI_00012840 05c8d4b325db755f94fdf14213f94029 456 PRINTS PR00344 Bacterial sensor protein C-terminal signature 403 413 1.5E-11 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFULGI_00012840 05c8d4b325db755f94fdf14213f94029 456 PRINTS PR00344 Bacterial sensor protein C-terminal signature 413 431 1.5E-11 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFULGI_00012840 05c8d4b325db755f94fdf14213f94029 456 PRINTS PR00344 Bacterial sensor protein C-terminal signature 385 399 1.5E-11 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFULGI_00012840 05c8d4b325db755f94fdf14213f94029 456 PRINTS PR00344 Bacterial sensor protein C-terminal signature 437 450 1.5E-11 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFULGI_00012840 05c8d4b325db755f94fdf14213f94029 456 SUPERFAMILY SSF55785 114 240 2.9E-26 T 01-11-2018 IPR035965 PAS domain superfamily AFULGI_00012840 05c8d4b325db755f94fdf14213f94029 456 SMART SM00388 255 318 0.008 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFULGI_00012840 05c8d4b325db755f94fdf14213f94029 456 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 125 246 7.7E-30 T 01-11-2018 IPR000014 PAS domain AFULGI_00012840 05c8d4b325db755f94fdf14213f94029 456 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 7 124 9.9E-17 T 01-11-2018 IPR000014 PAS domain AFULGI_00020940 38e949e0c45069a1bbd64f94be46e1e5 236 SUPERFAMILY SSF51735 3 116 1.65E-24 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily AFULGI_00020940 38e949e0c45069a1bbd64f94be46e1e5 236 Gene3D G3DSA:3.30.360.10 111 211 8.3E-95 T 01-11-2018 AFULGI_00020940 38e949e0c45069a1bbd64f94be46e1e5 236 TIGRFAM TIGR03855 NAD_NadX: aspartate dehydrogenase 24 236 3.3E-92 T 01-11-2018 IPR022487 L-aspartate dehydrogenase, archaeal GO:0033735|GO:0055114 KEGG: 00760+1.4.1.21 AFULGI_00020940 38e949e0c45069a1bbd64f94be46e1e5 236 SUPERFAMILY SSF55347 111 206 1.31E-23 T 01-11-2018 AFULGI_00020940 38e949e0c45069a1bbd64f94be46e1e5 236 Pfam PF01958 Domain of unknown function DUF108 142 223 5.3E-30 T 01-11-2018 IPR002811 Aspartate dehydrogenase GO:0006742|GO:0016491|GO:0019363|GO:0055114 KEGG: 00760+1.4.1.21 AFULGI_00020940 38e949e0c45069a1bbd64f94be46e1e5 236 PIRSF PIRSF005227 1 236 6.0E-87 T 01-11-2018 IPR011182 L-aspartate dehydrogenase GO:0009435|GO:0033735|GO:0055114 KEGG: 00760+1.4.1.21 AFULGI_00020940 38e949e0c45069a1bbd64f94be46e1e5 236 Hamap MF_01265 Probable L-aspartate dehydrogenase [nadX]. 1 236 31.584 T 01-11-2018 IPR020626 L-aspartate dehydrogenase, prokaryotic GO:0009435|GO:0033735|GO:0055114 KEGG: 00760+1.4.1.21 AFULGI_00020940 38e949e0c45069a1bbd64f94be46e1e5 236 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 7 107 4.0E-14 T 01-11-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 AFULGI_00020940 38e949e0c45069a1bbd64f94be46e1e5 236 Gene3D G3DSA:3.40.50.720 3 229 8.3E-95 T 01-11-2018 AFULGI_00015080 28018242fe9d1e609fd859a2a9b2ec02 311 Gene3D G3DSA:3.40.50.1980 52 176 2.6E-38 T 01-11-2018 AFULGI_00015080 28018242fe9d1e609fd859a2a9b2ec02 311 SUPERFAMILY SSF53807 44 310 2.39E-69 T 01-11-2018 AFULGI_00015080 28018242fe9d1e609fd859a2a9b2ec02 311 Gene3D G3DSA:3.40.50.1980 177 311 2.7E-37 T 01-11-2018 AFULGI_00015080 28018242fe9d1e609fd859a2a9b2ec02 311 Pfam PF01497 Periplasmic binding protein 56 289 8.2E-42 T 01-11-2018 IPR002491 ABC transporter periplasmic binding domain AFULGI_00003940 b62d7ee7ed07dc89bb32e87a22495fdd 241 Gene3D G3DSA:3.40.50.300 1 237 1.2E-53 T 01-11-2018 AFULGI_00003940 b62d7ee7ed07dc89bb32e87a22495fdd 241 SUPERFAMILY SSF52540 1 218 6.63E-53 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00003940 b62d7ee7ed07dc89bb32e87a22495fdd 241 SMART SM00382 26 204 3.8E-10 T 01-11-2018 IPR003593 AAA+ ATPase domain AFULGI_00003940 b62d7ee7ed07dc89bb32e87a22495fdd 241 Pfam PF00005 ABC transporter 18 157 6.6E-27 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFULGI_00006080 c9faa4eaa952536db193201e150a91ac 236 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 83 196 1.4E-10 T 01-11-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFULGI_00006080 c9faa4eaa952536db193201e150a91ac 236 Gene3D G3DSA:3.40.50.1000 17 227 9.1E-50 T 01-11-2018 IPR023214 HAD superfamily AFULGI_00006080 c9faa4eaa952536db193201e150a91ac 236 SUPERFAMILY SSF56784 12 234 1.03E-53 T 01-11-2018 IPR036412 HAD-like superfamily AFULGI_00006080 c9faa4eaa952536db193201e150a91ac 236 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 163 183 1.0E-10 T 01-11-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFULGI_00006080 c9faa4eaa952536db193201e150a91ac 236 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 145 161 1.0E-10 T 01-11-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFULGI_00006080 c9faa4eaa952536db193201e150a91ac 236 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 16 27 1.0E-10 T 01-11-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFULGI_00006080 c9faa4eaa952536db193201e150a91ac 236 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 114 127 1.0E-10 T 01-11-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFULGI_00006080 c9faa4eaa952536db193201e150a91ac 236 Pfam PF13419 Haloacid dehalogenase-like hydrolase 19 200 3.1E-38 T 01-11-2018 AFULGI_00006080 c9faa4eaa952536db193201e150a91ac 236 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 99 200 3.3E-12 T 01-11-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 AFULGI_00006080 c9faa4eaa952536db193201e150a91ac 236 Gene3D G3DSA:1.10.150.520 30 102 9.1E-50 T 01-11-2018 AFULGI_00006080 c9faa4eaa952536db193201e150a91ac 236 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 80 200 3.8E-13 T 01-11-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFULGI_00013380 73902d84a808d02735e807a5c726920c 430 TIGRFAM TIGR01415 trpB_rel: pyridoxal-phosphate dependent TrpB-like enzyme 11 425 5.5E-212 T 01-11-2018 IPR006316 Tryptophan synthase, beta chain-like GO:0000162|GO:0004834|GO:0030170 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 AFULGI_00013380 73902d84a808d02735e807a5c726920c 430 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 103 117 - T 01-11-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 AFULGI_00013380 73902d84a808d02735e807a5c726920c 430 PIRSF PIRSF001413 7 429 3.3E-130 T 01-11-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 AFULGI_00013380 73902d84a808d02735e807a5c726920c 430 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 75 410 8.8E-41 T 01-11-2018 IPR001926 Pyridoxal-phosphate dependent enzyme AFULGI_00013380 73902d84a808d02735e807a5c726920c 430 Gene3D G3DSA:3.40.50.1100 12 236 1.7E-176 T 01-11-2018 AFULGI_00013380 73902d84a808d02735e807a5c726920c 430 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 19 423 41.902 T 01-11-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 AFULGI_00013380 73902d84a808d02735e807a5c726920c 430 Gene3D G3DSA:3.40.50.1100 11 416 1.7E-176 T 01-11-2018 AFULGI_00013380 73902d84a808d02735e807a5c726920c 430 PIRSF PIRSF500824 1 430 1.0E-216 T 01-11-2018 IPR006316 Tryptophan synthase, beta chain-like GO:0000162|GO:0004834|GO:0030170 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 AFULGI_00013380 73902d84a808d02735e807a5c726920c 430 SUPERFAMILY SSF53686 25 423 3.8E-113 T 01-11-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme AFULGI_00000530 fdecfc55f5e574b78300a34b80b63cab 93 Gene3D G3DSA:1.10.287.1080 1 93 1.6E-62 T 01-11-2018 AFULGI_00000530 fdecfc55f5e574b78300a34b80b63cab 93 SUPERFAMILY SSF101386 1 84 2.47E-55 T 01-11-2018 AFULGI_00000530 fdecfc55f5e574b78300a34b80b63cab 93 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 35 70 7.1E-7 T 01-11-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core AFULGI_00018810 03cb7125e8c0f45cbdd8dc635139ba73 82 TIGRFAM TIGR00286 TIGR00286: arginine decarboxylase, pyruvoyl-dependent 3 82 2.7E-34 T 01-11-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 AFULGI_00018810 03cb7125e8c0f45cbdd8dc635139ba73 82 Hamap MF_01404 Pyruvoyl-dependent arginine decarboxylase [pdaD]. 1 82 42.27 T 01-11-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 AFULGI_00018810 03cb7125e8c0f45cbdd8dc635139ba73 82 Pfam PF01862 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) 4 81 8.6E-33 T 01-11-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 AFULGI_00018810 03cb7125e8c0f45cbdd8dc635139ba73 82 SUPERFAMILY SSF56271 3 81 9.94E-29 T 01-11-2018 IPR016104 Pyruvoyl-dependent histidine/arginine decarboxylase GO:0006520|GO:0016831 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 AFULGI_00018810 03cb7125e8c0f45cbdd8dc635139ba73 82 Gene3D G3DSA:3.50.20.10 1 82 7.6E-27 T 01-11-2018 IPR016105 Pyruvoyl-dependent histidine/arginine decarboxylase, 3-layer sandwich domain GO:0006520|GO:0016831 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 AFULGI_00018810 03cb7125e8c0f45cbdd8dc635139ba73 82 ProDom PD010449 DECARBOXYLASE PYRUVOYL-DEPENDENT ARGININE SUBUNIT ALPHA CONTAINS: BETA PVLARGDC LYA DECARBOX 5 82 6.0E-32 T 01-11-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 AFULGI_00021440 f49ad33a8c7596e134ec0015502bb6a6 76 Hamap MF_00025 DNA-directed RNA polymerase subunit H [rpoH]. 3 76 24.313 T 01-11-2018 IPR020609 Archaeal RpoH /eukaryotic RPB5 RNA polymerase subunit GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 AFULGI_00021440 f49ad33a8c7596e134ec0015502bb6a6 76 SUPERFAMILY SSF55287 2 76 2.22E-27 T 01-11-2018 IPR035913 RPB5-like RNA polymerase subunit superfamily Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 AFULGI_00021440 f49ad33a8c7596e134ec0015502bb6a6 76 ProSitePatterns PS01110 RNA polymerases H / 23 Kd subunits signature. 8 21 - T 01-11-2018 IPR020608 RNA polymerase, subunit H/Rpb5, conserved site Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 AFULGI_00021440 f49ad33a8c7596e134ec0015502bb6a6 76 Gene3D G3DSA:3.90.940.20 1 76 8.3E-33 T 01-11-2018 IPR035913 RPB5-like RNA polymerase subunit superfamily Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 AFULGI_00021440 f49ad33a8c7596e134ec0015502bb6a6 76 ProDom PD005155 RNA POLYMERASE DNA-DIRECTED SUBUNIT NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION II H POLYPEPTIDE 10 75 5.0E-30 T 01-11-2018 IPR000783 RNA polymerase, subunit H/Rpb5 C-terminal GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 AFULGI_00021440 f49ad33a8c7596e134ec0015502bb6a6 76 Pfam PF01191 RNA polymerase Rpb5, C-terminal domain 4 75 4.9E-32 T 01-11-2018 IPR000783 RNA polymerase, subunit H/Rpb5 C-terminal GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 AFULGI_00025750 8a186804fb00ee474ada8b6fa3aca47f 199 Pfam PF03167 Uracil DNA glycosylase superfamily 28 177 3.9E-44 T 01-11-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 AFULGI_00025750 8a186804fb00ee474ada8b6fa3aca47f 199 TIGRFAM TIGR00758 UDG_fam4: uracil-DNA glycosylase, family 4 14 189 8.2E-84 T 01-11-2018 IPR005273 Uracil-DNA glycosylase family 4 AFULGI_00025750 8a186804fb00ee474ada8b6fa3aca47f 199 Gene3D G3DSA:3.40.470.10 1 190 4.5E-70 T 01-11-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 AFULGI_00025750 8a186804fb00ee474ada8b6fa3aca47f 199 SMART SM00986 28 182 2.5E-38 T 01-11-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 AFULGI_00025750 8a186804fb00ee474ada8b6fa3aca47f 199 SUPERFAMILY SSF52141 2 186 7.19E-60 T 01-11-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 AFULGI_00025750 8a186804fb00ee474ada8b6fa3aca47f 199 SMART SM00987 28 182 2.5E-38 T 01-11-2018 AFULGI_00013370 3bd3a5bc819edf60d7fd5cc3a459da40 74 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 54 65 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFULGI_00013370 3bd3a5bc819edf60d7fd5cc3a459da40 74 Gene3D G3DSA:3.30.70.20 2 73 8.7E-11 T 01-11-2018 AFULGI_00013370 3bd3a5bc819edf60d7fd5cc3a459da40 74 SUPERFAMILY SSF54862 3 72 1.57E-12 T 01-11-2018 AFULGI_00013370 3bd3a5bc819edf60d7fd5cc3a459da40 74 Pfam PF12838 4Fe-4S dicluster domain 11 67 1.3E-6 T 01-11-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFULGI_00012580 378e8ccc831119921742f34146412bc8 470 SUPERFAMILY SSF51246 387 467 3.14E-18 T 01-11-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 AFULGI_00012580 378e8ccc831119921742f34146412bc8 470 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 1 469 1.1E-183 T 01-11-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 AFULGI_00012580 378e8ccc831119921742f34146412bc8 470 SUPERFAMILY SSF52440 1 108 1.35E-23 T 01-11-2018 IPR016185 Pre-ATP-grasp domain superfamily AFULGI_00012580 378e8ccc831119921742f34146412bc8 470 SMART SM01209 109 334 8.9E-88 T 01-11-2018 AFULGI_00012580 378e8ccc831119921742f34146412bc8 470 SUPERFAMILY SSF56059 110 360 8.31E-42 T 01-11-2018 AFULGI_00012580 378e8ccc831119921742f34146412bc8 470 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 1 108 8.3E-26 T 01-11-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 AFULGI_00012580 378e8ccc831119921742f34146412bc8 470 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 387 466 1.6E-18 T 01-11-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 AFULGI_00012580 378e8ccc831119921742f34146412bc8 470 Gene3D G3DSA:3.40.50.20 2 101 9.1E-27 T 01-11-2018 AFULGI_00012580 378e8ccc831119921742f34146412bc8 470 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 469 37.889 T 01-11-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 AFULGI_00012580 378e8ccc831119921742f34146412bc8 470 Gene3D G3DSA:3.30.1490.20 127 197 4.1E-29 T 01-11-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 AFULGI_00012580 378e8ccc831119921742f34146412bc8 470 SMART SM01210 368 469 2.0E-26 T 01-11-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 AFULGI_00012580 378e8ccc831119921742f34146412bc8 470 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 109 334 2.2E-84 T 01-11-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 AFULGI_00012580 378e8ccc831119921742f34146412bc8 470 Gene3D G3DSA:3.90.600.10 385 470 9.5E-23 T 01-11-2018 IPR037123 Phosphoribosylglycinamide synthetase, C-domain superfamily GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 AFULGI_00023730 1c3f42544706ed79b3768b0a554438e7 89 Gene3D G3DSA:3.10.20.30 1 89 4.3E-16 T 01-11-2018 IPR012675 Beta-grasp domain superfamily AFULGI_00023730 1c3f42544706ed79b3768b0a554438e7 89 SUPERFAMILY SSF54285 2 89 1.29E-11 T 01-11-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp AFULGI_00023730 1c3f42544706ed79b3768b0a554438e7 89 Pfam PF02597 ThiS family 5 89 1.5E-11 T 01-11-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 AFULGI_00023730 1c3f42544706ed79b3768b0a554438e7 89 TIGRFAM TIGR01687 moaD_arch: MoaD family protein 3 89 7.9E-15 T 01-11-2018 IPR010038 MoaD, archaeal-type AFULGI_00003310 ead814e495cc76ae2792a0d9f517d06d 362 Gene3D G3DSA:3.10.580.10 195 287 1.1E-14 T 01-11-2018 AFULGI_00003310 ead814e495cc76ae2792a0d9f517d06d 362 Pfam PF00571 CBS domain 234 286 1.7E-14 T 01-11-2018 IPR000644 CBS domain AFULGI_00003310 ead814e495cc76ae2792a0d9f517d06d 362 Pfam PF00571 CBS domain 292 343 3.6E-15 T 01-11-2018 IPR000644 CBS domain AFULGI_00003310 ead814e495cc76ae2792a0d9f517d06d 362 SMART SM00116 299 346 2.3E-13 T 01-11-2018 IPR000644 CBS domain AFULGI_00003310 ead814e495cc76ae2792a0d9f517d06d 362 SMART SM00116 241 288 9.1E-13 T 01-11-2018 IPR000644 CBS domain AFULGI_00003310 ead814e495cc76ae2792a0d9f517d06d 362 Gene3D G3DSA:3.10.580.10 288 346 3.9E-17 T 01-11-2018 AFULGI_00003310 ead814e495cc76ae2792a0d9f517d06d 362 SUPERFAMILY SSF54631 228 343 1.52E-36 T 01-11-2018 AFULGI_00003310 ead814e495cc76ae2792a0d9f517d06d 362 Pfam PF02163 Peptidase family M50 134 193 1.4E-9 T 01-11-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 AFULGI_00003310 ead814e495cc76ae2792a0d9f517d06d 362 PIRSF PIRSF006404 1 354 1.7E-125 T 01-11-2018 IPR016483 Uncharacterised conserved protein UCP006404, peptidase M50/CBS AFULGI_00008480 c0989273457f66761c46b6b8cab8d3b6 151 Pfam PF00334 Nucleoside diphosphate kinase 2 136 1.1E-61 T 01-11-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 AFULGI_00008480 c0989273457f66761c46b6b8cab8d3b6 151 SMART SM00562 1 138 2.5E-98 T 01-11-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 AFULGI_00008480 c0989273457f66761c46b6b8cab8d3b6 151 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 112 120 - T 01-11-2018 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AFULGI_00008480 c0989273457f66761c46b6b8cab8d3b6 151 SUPERFAMILY SSF54919 1 149 1.27E-66 T 01-11-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 AFULGI_00008480 c0989273457f66761c46b6b8cab8d3b6 151 PRINTS PR01243 Nucleoside diphosphate kinase signature 112 131 5.0E-52 T 01-11-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 AFULGI_00008480 c0989273457f66761c46b6b8cab8d3b6 151 PRINTS PR01243 Nucleoside diphosphate kinase signature 89 105 5.0E-52 T 01-11-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 AFULGI_00008480 c0989273457f66761c46b6b8cab8d3b6 151 PRINTS PR01243 Nucleoside diphosphate kinase signature 68 85 5.0E-52 T 01-11-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 AFULGI_00008480 c0989273457f66761c46b6b8cab8d3b6 151 PRINTS PR01243 Nucleoside diphosphate kinase signature 4 26 5.0E-52 T 01-11-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 AFULGI_00008480 c0989273457f66761c46b6b8cab8d3b6 151 PRINTS PR01243 Nucleoside diphosphate kinase signature 48 67 5.0E-52 T 01-11-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 AFULGI_00008480 c0989273457f66761c46b6b8cab8d3b6 151 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 1 136 39.677 T 01-11-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 AFULGI_00008480 c0989273457f66761c46b6b8cab8d3b6 151 Gene3D G3DSA:3.30.70.141 1 151 1.1E-70 T 01-11-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 AFULGI_00002370 8b996df801d88a86af2164d40696d25b 394 Pfam PF01699 Sodium/calcium exchanger protein 209 354 1.7E-14 T 01-11-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 AFULGI_00002370 8b996df801d88a86af2164d40696d25b 394 Pfam PF01699 Sodium/calcium exchanger protein 39 181 5.3E-22 T 01-11-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 AFULGI_00002370 8b996df801d88a86af2164d40696d25b 394 Gene3D G3DSA:1.20.58.1130 42 241 3.7E-17 T 01-11-2018 AFULGI_00002370 8b996df801d88a86af2164d40696d25b 394 Gene3D G3DSA:1.20.1420.30 61 349 3.7E-17 T 01-11-2018 AFULGI_00004440 21153a1b9ec2a562d2ef9bd831b7b48a 115 Gene3D G3DSA:3.30.479.10 4 115 1.0E-36 T 01-11-2018 IPR038418 6-pyruvoyl tetrahydropterin synthase/QueD superfamily Reactome: R-HSA-1474151 AFULGI_00004440 21153a1b9ec2a562d2ef9bd831b7b48a 115 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 10 114 5.2E-31 T 01-11-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 AFULGI_00004440 21153a1b9ec2a562d2ef9bd831b7b48a 115 TIGRFAM TIGR03367 queuosine_QueD: queuosine biosynthesis protein QueD 7 92 3.0E-30 T 01-11-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 AFULGI_00004440 21153a1b9ec2a562d2ef9bd831b7b48a 115 PIRSF PIRSF006113 2 115 8.1E-49 T 01-11-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 AFULGI_00004440 21153a1b9ec2a562d2ef9bd831b7b48a 115 SUPERFAMILY SSF55620 5 114 2.56E-34 T 01-11-2018 AFULGI_00021480 95d8c4c398592ee07d49063e6cabd262 380 Pfam PF04998 RNA polymerase Rpb1, domain 5 52 324 5.4E-59 T 01-11-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFULGI_00021480 95d8c4c398592ee07d49063e6cabd262 380 SUPERFAMILY SSF64484 26 376 3.89E-104 T 01-11-2018 AFULGI_00021480 95d8c4c398592ee07d49063e6cabd262 380 TIGRFAM TIGR02389 RNA_pol_rpoA2: DNA-directed RNA polymerase, subunit A'' 15 374 4.5E-156 T 01-11-2018 IPR012757 DNA-directed RNA polymerase subunit A'' GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFULGI_00021480 95d8c4c398592ee07d49063e6cabd262 380 Gene3D G3DSA:1.10.150.390 325 370 2.7E-23 T 01-11-2018 AFULGI_00021480 95d8c4c398592ee07d49063e6cabd262 380 Hamap MF_00411 DNA-directed RNA polymerase subunit A'' [rpoA2]. 2 377 40.926 T 01-11-2018 IPR012757 DNA-directed RNA polymerase subunit A'' GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFULGI_00015220 49bba8ef95fd2769d1983ec3c4bcd809 318 Gene3D G3DSA:3.30.420.10 143 309 9.8E-23 T 01-11-2018 IPR036397 Ribonuclease H superfamily GO:0003676 AFULGI_00015220 49bba8ef95fd2769d1983ec3c4bcd809 318 SUPERFAMILY SSF46689 21 128 6.72E-15 T 01-11-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFULGI_00015220 49bba8ef95fd2769d1983ec3c4bcd809 318 Pfam PF00665 Integrase core domain 148 264 1.7E-25 T 01-11-2018 IPR001584 Integrase, catalytic core GO:0015074 AFULGI_00015220 49bba8ef95fd2769d1983ec3c4bcd809 318 SUPERFAMILY SSF53098 144 289 1.18E-28 T 01-11-2018 IPR012337 Ribonuclease H-like superfamily AFULGI_00015220 49bba8ef95fd2769d1983ec3c4bcd809 318 Pfam PF13518 Helix-turn-helix domain 31 77 1.0E-8 T 01-11-2018 AFULGI_00002570 fc8945099f0fecc220dfdb8a55f3ac0b 167 Pfam PF00994 Probable molybdopterin binding domain 11 158 2.1E-34 T 01-11-2018 IPR001453 MoaB/Mog domain AFULGI_00002570 fc8945099f0fecc220dfdb8a55f3ac0b 167 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 8 153 3.9E-37 T 01-11-2018 IPR001453 MoaB/Mog domain AFULGI_00002570 fc8945099f0fecc220dfdb8a55f3ac0b 167 SUPERFAMILY SSF53218 8 164 7.46E-36 T 01-11-2018 IPR036425 MoaB/Mog-like domain superfamily AFULGI_00002570 fc8945099f0fecc220dfdb8a55f3ac0b 167 SMART SM00852 11 159 2.0E-20 T 01-11-2018 IPR001453 MoaB/Mog domain AFULGI_00002570 fc8945099f0fecc220dfdb8a55f3ac0b 167 Gene3D G3DSA:3.40.980.10 3 167 2.5E-42 T 01-11-2018 IPR036425 MoaB/Mog-like domain superfamily AFULGI_00002570 fc8945099f0fecc220dfdb8a55f3ac0b 167 PIRSF PIRSF006443 1 167 1.6E-57 T 01-11-2018 IPR012245 Molybdenum cofactor biosynthesis protein MoaB GO:0006777 AFULGI_00005000 e5da07099a34666258e24d777ee6495e 223 Pfam PF14382 Exosome complex exonuclease RRP4 N-terminal region 4 36 2.3E-6 T 01-11-2018 IPR025721 Exosome complex component, N-terminal domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 AFULGI_00005000 e5da07099a34666258e24d777ee6495e 223 Gene3D G3DSA:2.40.50.140 50 136 2.7E-35 T 01-11-2018 AFULGI_00005000 e5da07099a34666258e24d777ee6495e 223 SMART SM00322 134 198 2.8E-8 T 01-11-2018 IPR004087 K Homology domain GO:0003676 AFULGI_00005000 e5da07099a34666258e24d777ee6495e 223 SUPERFAMILY SSF54791 137 214 2.67E-17 T 01-11-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 AFULGI_00005000 e5da07099a34666258e24d777ee6495e 223 Pfam PF00575 S1 RNA binding domain 55 126 9.3E-8 T 01-11-2018 IPR003029 S1 domain GO:0003676 AFULGI_00005000 e5da07099a34666258e24d777ee6495e 223 SUPERFAMILY SSF110324 2 51 2.15E-12 T 01-11-2018 AFULGI_00005000 e5da07099a34666258e24d777ee6495e 223 Pfam PF15985 KH domain 137 182 9.3E-7 T 01-11-2018 IPR004088 K Homology domain, type 1 GO:0003723 AFULGI_00005000 e5da07099a34666258e24d777ee6495e 223 Gene3D G3DSA:2.40.50.100 1 49 3.4E-19 T 01-11-2018 AFULGI_00005000 e5da07099a34666258e24d777ee6495e 223 SUPERFAMILY SSF50249 51 139 3.21E-22 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold AFULGI_00005000 e5da07099a34666258e24d777ee6495e 223 Gene3D G3DSA:3.30.1370.10 137 223 1.6E-37 T 01-11-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 AFULGI_00005000 e5da07099a34666258e24d777ee6495e 223 SMART SM00316 56 127 2.6E-17 T 01-11-2018 IPR022967 RNA-binding domain, S1 AFULGI_00005000 e5da07099a34666258e24d777ee6495e 223 Hamap MF_00623 Exosome complex component Rrp4 [rrp4]. 1 219 35.922 T 01-11-2018 IPR023474 Exosome complex component Rrp4 GO:0000178|GO:0008143 AFULGI_00001920 c4f7f26ebf253451b93e7c11e7974754 86 ProSitePatterns PS01154 RNA polymerases L / 13 to 16 Kd subunits signature. 17 48 - T 01-11-2018 IPR008193 DNA-directed RNA polymerase Rpb11, 13-16kDa subunit, conserved site GO:0003677|GO:0003899|GO:0006351 AFULGI_00001920 c4f7f26ebf253451b93e7c11e7974754 86 Gene3D G3DSA:3.30.1360.10 1 86 5.6E-25 T 01-11-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFULGI_00001920 c4f7f26ebf253451b93e7c11e7974754 86 SUPERFAMILY SSF55257 1 85 1.57E-25 T 01-11-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFULGI_00001920 c4f7f26ebf253451b93e7c11e7974754 86 Pfam PF13656 RNA polymerase Rpb3/Rpb11 dimerisation domain 13 84 1.6E-21 T 01-11-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 AFULGI_00001920 c4f7f26ebf253451b93e7c11e7974754 86 Hamap MF_00261 DNA-directed RNA polymerase subunit L [rpoL]. 1 86 20.151 T 01-11-2018 IPR022905 DNA-directed RNA polymerase subunit L (Rpo11) GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFULGI_00018000 d03ada3310b562d4599e07ab970cb3c5 280 SUPERFAMILY SSF82861 16 98 1.7E-11 T 01-11-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 AFULGI_00018000 d03ada3310b562d4599e07ab970cb3c5 280 Gene3D G3DSA:2.30.30.60 115 164 3.6E-15 T 01-11-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily AFULGI_00018000 d03ada3310b562d4599e07ab970cb3c5 280 ProSitePatterns PS01246 Uncharacterized protein family UPF0003 signature. 129 163 - T 01-11-2018 IPR006686 Mechanosensitive ion channel MscS, conserved site GO:0016020 AFULGI_00018000 d03ada3310b562d4599e07ab970cb3c5 280 SUPERFAMILY SSF82689 170 265 1.57E-33 T 01-11-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 AFULGI_00018000 d03ada3310b562d4599e07ab970cb3c5 280 Pfam PF00924 Mechanosensitive ion channel 57 254 9.9E-63 T 01-11-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 AFULGI_00018000 d03ada3310b562d4599e07ab970cb3c5 280 Gene3D G3DSA:3.30.70.100 167 258 1.9E-29 T 01-11-2018 AFULGI_00018000 d03ada3310b562d4599e07ab970cb3c5 280 SUPERFAMILY SSF50182 100 164 1.14E-17 T 01-11-2018 IPR010920 LSM domain superfamily AFULGI_00009230 b58725bae68d57c28e5bc1258919d670 478 PIRSF PIRSF006247 1 476 3.1E-176 T 01-11-2018 IPR004772 TrkH potassium transport family GO:0015379|GO:0016021|GO:0071805 AFULGI_00009230 b58725bae68d57c28e5bc1258919d670 478 Pfam PF02386 Cation transport protein 45 470 3.0E-63 T 01-11-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 AFULGI_00009230 b58725bae68d57c28e5bc1258919d670 478 TIGRFAM TIGR00933 2a38: potassium uptake protein, TrkH family 85 459 3.4E-116 T 01-11-2018 IPR004772 TrkH potassium transport family GO:0015379|GO:0016021|GO:0071805 AFULGI_00012400 73f96aad74373abcf900db82bdf7bff9 387 SUPERFAMILY SSF56645 3 245 1.27E-82 T 01-11-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 AFULGI_00012400 73f96aad74373abcf900db82bdf7bff9 387 SUPERFAMILY SSF47203 232 385 7.78E-54 T 01-11-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 AFULGI_00012400 73f96aad74373abcf900db82bdf7bff9 387 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 124 222 1.0E-27 T 01-11-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 AFULGI_00012400 73f96aad74373abcf900db82bdf7bff9 387 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 8 120 2.8E-33 T 01-11-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 AFULGI_00012400 73f96aad74373abcf900db82bdf7bff9 387 PIRSF PIRSF016578 6 373 3.3E-21 T 01-11-2018 AFULGI_00012400 73f96aad74373abcf900db82bdf7bff9 387 Gene3D G3DSA:1.10.540.10 1 120 3.4E-39 T 01-11-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 AFULGI_00012400 73f96aad74373abcf900db82bdf7bff9 387 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 234 384 2.0E-48 T 01-11-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AFULGI_00012400 73f96aad74373abcf900db82bdf7bff9 387 Gene3D G3DSA:2.40.110.10 124 238 4.5E-44 T 01-11-2018 AFULGI_00012400 73f96aad74373abcf900db82bdf7bff9 387 Gene3D G3DSA:1.20.140.10 239 386 1.2E-51 T 01-11-2018 AFULGI_00025260 5ca02c5d48a53ceb4402016afc3d9dfb 734 SUPERFAMILY SSF48113 6 404 8.69E-137 T 01-11-2018 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 AFULGI_00025260 5ca02c5d48a53ceb4402016afc3d9dfb 734 ProSitePatterns PS00436 Peroxidases active site signature. 71 82 - T 01-11-2018 IPR019794 Peroxidase, active site GO:0004601|GO:0055114 AFULGI_00025260 5ca02c5d48a53ceb4402016afc3d9dfb 734 Gene3D G3DSA:1.10.420.20 172 372 3.7E-188 T 01-11-2018 AFULGI_00025260 5ca02c5d48a53ceb4402016afc3d9dfb 734 Gene3D G3DSA:1.10.520.10 408 718 8.8E-132 T 01-11-2018 AFULGI_00025260 5ca02c5d48a53ceb4402016afc3d9dfb 734 ProSitePatterns PS00435 Peroxidases proximal heme-ligand signature. 234 244 - T 01-11-2018 IPR019793 Peroxidases heam-ligand binding site Reactome: R-HSA-2408557 AFULGI_00025260 5ca02c5d48a53ceb4402016afc3d9dfb 734 SUPERFAMILY SSF48113 405 718 5.6E-101 T 01-11-2018 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 AFULGI_00025260 5ca02c5d48a53ceb4402016afc3d9dfb 734 TIGRFAM TIGR00198 cat_per_HPI: catalase/peroxidase HPI 1 721 0.0 T 01-11-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 AFULGI_00025260 5ca02c5d48a53ceb4402016afc3d9dfb 734 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 9 31 2.4E-43 T 01-11-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 AFULGI_00025260 5ca02c5d48a53ceb4402016afc3d9dfb 734 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 242 265 2.4E-43 T 01-11-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 AFULGI_00025260 5ca02c5d48a53ceb4402016afc3d9dfb 734 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 455 481 2.4E-43 T 01-11-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 AFULGI_00025260 5ca02c5d48a53ceb4402016afc3d9dfb 734 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 33 46 2.4E-43 T 01-11-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 AFULGI_00025260 5ca02c5d48a53ceb4402016afc3d9dfb 734 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 48 73 2.4E-43 T 01-11-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 AFULGI_00025260 5ca02c5d48a53ceb4402016afc3d9dfb 734 Hamap MF_01961 Catalase-peroxidase [katG]. 2 719 38.801 T 01-11-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 AFULGI_00025260 5ca02c5d48a53ceb4402016afc3d9dfb 734 PRINTS PR00458 Haem peroxidase superfamily signature 293 308 1.3E-15 T 01-11-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 AFULGI_00025260 5ca02c5d48a53ceb4402016afc3d9dfb 734 PRINTS PR00458 Haem peroxidase superfamily signature 234 249 1.3E-15 T 01-11-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 AFULGI_00025260 5ca02c5d48a53ceb4402016afc3d9dfb 734 PRINTS PR00458 Haem peroxidase superfamily signature 131 148 1.3E-15 T 01-11-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 AFULGI_00025260 5ca02c5d48a53ceb4402016afc3d9dfb 734 PRINTS PR00458 Haem peroxidase superfamily signature 71 85 1.3E-15 T 01-11-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 AFULGI_00025260 5ca02c5d48a53ceb4402016afc3d9dfb 734 PRINTS PR00458 Haem peroxidase superfamily signature 149 161 1.3E-15 T 01-11-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 AFULGI_00025260 5ca02c5d48a53ceb4402016afc3d9dfb 734 Pfam PF00141 Peroxidase 378 691 4.6E-32 T 01-11-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 AFULGI_00025260 5ca02c5d48a53ceb4402016afc3d9dfb 734 Pfam PF00141 Peroxidase 65 370 7.2E-44 T 01-11-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 AFULGI_00025260 5ca02c5d48a53ceb4402016afc3d9dfb 734 Gene3D G3DSA:1.10.420.10 564 694 8.8E-132 T 01-11-2018 AFULGI_00025260 5ca02c5d48a53ceb4402016afc3d9dfb 734 Gene3D G3DSA:1.10.520.10 9 405 3.7E-188 T 01-11-2018 AFULGI_00007050 249ea7f6f96fc30097bd30c90ce576a7 278 Hamap MF_00562 D-aminoacyl-tRNA deacylase [dtdA]. 1 267 35.398 T 01-11-2018 IPR018033 D-aminoacyl-tRNA deacylase, archaea GO:0016788|GO:0019478|GO:0051499 AFULGI_00007050 249ea7f6f96fc30097bd30c90ce576a7 278 Pfam PF04414 D-aminoacyl-tRNA deacylase 66 265 7.9E-70 T 01-11-2018 IPR007508 D-aminoacyl-tRNA deacylase DtdA GO:0016788|GO:0051499 AFULGI_00007050 249ea7f6f96fc30097bd30c90ce576a7 278 Gene3D G3DSA:3.40.630.50 1 182 1.5E-69 T 01-11-2018 AFULGI_00007050 249ea7f6f96fc30097bd30c90ce576a7 278 Gene3D G3DSA:3.40.50.10700 183 278 2.4E-36 T 01-11-2018 AFULGI_00007050 249ea7f6f96fc30097bd30c90ce576a7 278 SUPERFAMILY SSF142535 1 275 5.23E-86 T 01-11-2018 AFULGI_00007050 249ea7f6f96fc30097bd30c90ce576a7 278 PIRSF PIRSF016210 1 268 2.2E-91 T 01-11-2018 IPR018033 D-aminoacyl-tRNA deacylase, archaea GO:0016788|GO:0019478|GO:0051499 AFULGI_00007570 bd8ae29c812ef439e76c95b08ca83ad7 643 Pfam PF13193 AMP-binding enzyme C-terminal domain 525 603 2.0E-27 T 01-11-2018 IPR025110 AMP-binding enzyme, C-terminal domain AFULGI_00007570 bd8ae29c812ef439e76c95b08ca83ad7 643 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 5 61 3.8E-18 T 01-11-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 AFULGI_00007570 bd8ae29c812ef439e76c95b08ca83ad7 643 Gene3D G3DSA:3.40.50.12780 36 510 3.2E-88 T 01-11-2018 AFULGI_00007570 bd8ae29c812ef439e76c95b08ca83ad7 643 SUPERFAMILY SSF56801 4 635 6.67E-153 T 01-11-2018 AFULGI_00007570 bd8ae29c812ef439e76c95b08ca83ad7 643 Gene3D G3DSA:3.30.300.30 512 642 8.2E-30 T 01-11-2018 AFULGI_00007570 bd8ae29c812ef439e76c95b08ca83ad7 643 Pfam PF00501 AMP-binding enzyme 64 516 2.1E-82 T 01-11-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFULGI_00010330 90df3af6b88d488400c0e5cb8f4a01ef 225 TIGRFAM TIGR00021 rpiA: ribose 5-phosphate isomerase A 6 220 1.8E-66 T 01-11-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 AFULGI_00010330 90df3af6b88d488400c0e5cb8f4a01ef 225 Hamap MF_00170 Ribose-5-phosphate isomerase A [rpiA]. 2 225 32.603 T 01-11-2018 IPR020672 Ribose-5-phosphate isomerase, type A, subgroup GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 AFULGI_00010330 90df3af6b88d488400c0e5cb8f4a01ef 225 Pfam PF06026 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) 51 219 5.8E-56 T 01-11-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 AFULGI_00010330 90df3af6b88d488400c0e5cb8f4a01ef 225 Gene3D G3DSA:3.30.70.260 121 195 5.0E-71 T 01-11-2018 AFULGI_00010330 90df3af6b88d488400c0e5cb8f4a01ef 225 Gene3D G3DSA:3.40.50.1360 6 214 5.0E-71 T 01-11-2018 AFULGI_00010330 90df3af6b88d488400c0e5cb8f4a01ef 225 SUPERFAMILY SSF75445 129 206 7.98E-18 T 01-11-2018 AFULGI_00010330 90df3af6b88d488400c0e5cb8f4a01ef 225 SUPERFAMILY SSF100950 6 176 6.55E-40 T 01-11-2018 IPR037171 NagB/RpiA transferase-like AFULGI_00001270 39199cd220693795128cbe0385c4be2d 359 Pfam PF00850 Histone deacetylase domain 20 296 5.2E-81 T 01-11-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 AFULGI_00001270 39199cd220693795128cbe0385c4be2d 359 SUPERFAMILY SSF52768 3 358 3.41E-111 T 01-11-2018 IPR023696 Ureohydrolase domain superfamily AFULGI_00001270 39199cd220693795128cbe0385c4be2d 359 PRINTS PR01271 Histone deacetylase signature 217 235 1.1E-7 T 01-11-2018 IPR003084 Histone deacetylase GO:0004407|GO:0016575 Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862|Reactome: R-HSA-3214815 AFULGI_00001270 39199cd220693795128cbe0385c4be2d 359 PRINTS PR01271 Histone deacetylase signature 200 213 1.1E-7 T 01-11-2018 IPR003084 Histone deacetylase GO:0004407|GO:0016575 Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862|Reactome: R-HSA-3214815 AFULGI_00001270 39199cd220693795128cbe0385c4be2d 359 PRINTS PR01271 Histone deacetylase signature 57 75 1.1E-7 T 01-11-2018 IPR003084 Histone deacetylase GO:0004407|GO:0016575 Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862|Reactome: R-HSA-3214815 AFULGI_00001270 39199cd220693795128cbe0385c4be2d 359 Gene3D G3DSA:3.40.800.20 2 358 1.2E-110 T 01-11-2018 IPR037138 Histone deacetylase domain superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 AFULGI_00001270 39199cd220693795128cbe0385c4be2d 359 PRINTS PR01270 Histone deacetylase superfamily signature 122 145 5.0E-15 T 01-11-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 AFULGI_00001270 39199cd220693795128cbe0385c4be2d 359 PRINTS PR01270 Histone deacetylase superfamily signature 239 249 5.0E-15 T 01-11-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 AFULGI_00001270 39199cd220693795128cbe0385c4be2d 359 PRINTS PR01270 Histone deacetylase superfamily signature 155 170 5.0E-15 T 01-11-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 AFULGI_00009050 fb6c4458c3644c535f93793c14b21c17 271 SUPERFAMILY SSF51366 1 270 3.3E-81 T 01-11-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 AFULGI_00009050 fb6c4458c3644c535f93793c14b21c17 271 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 1 270 50.728 T 01-11-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 AFULGI_00009050 fb6c4458c3644c535f93793c14b21c17 271 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 1 270 7.0E-129 T 01-11-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 AFULGI_00009050 fb6c4458c3644c535f93793c14b21c17 271 Gene3D G3DSA:3.20.20.70 1 271 7.0E-107 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFULGI_00009050 fb6c4458c3644c535f93793c14b21c17 271 Pfam PF00977 Histidine biosynthesis protein 5 253 1.9E-91 T 01-11-2018 IPR006062 Histidine biosynthesis GO:0000105 AFULGI_00007990 e0c80867f70e43bb02217edfa30af93f 264 SUPERFAMILY SSF56281 17 247 2.8E-19 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFULGI_00007990 e0c80867f70e43bb02217edfa30af93f 264 Gene3D G3DSA:3.60.15.10 1 264 1.2E-64 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFULGI_00003210 4214e02f78b7b81c4daa017bae8c41bd 332 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 303 1.7E-85 T 01-11-2018 IPR016040 NAD(P)-binding domain AFULGI_00003210 4214e02f78b7b81c4daa017bae8c41bd 332 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 2 317 5.0E-163 T 01-11-2018 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|KEGG: 00525+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 AFULGI_00003210 4214e02f78b7b81c4daa017bae8c41bd 332 SUPERFAMILY SSF51735 1 319 3.95E-99 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily AFULGI_00003210 4214e02f78b7b81c4daa017bae8c41bd 332 Gene3D G3DSA:3.40.50.720 4 293 1.0E-131 T 01-11-2018 AFULGI_00003210 4214e02f78b7b81c4daa017bae8c41bd 332 Gene3D G3DSA:3.90.25.10 176 308 1.0E-131 T 01-11-2018 AFULGI_00022660 0f8a618e45424145c7a3c813a77594b5 347 Gene3D G3DSA:3.40.640.10 41 255 4.0E-94 T 01-11-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFULGI_00022660 0f8a618e45424145c7a3c813a77594b5 347 Gene3D G3DSA:3.90.1150.10 7 338 4.0E-94 T 01-11-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFULGI_00022660 0f8a618e45424145c7a3c813a77594b5 347 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 1 345 56.291 T 01-11-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 AFULGI_00022660 0f8a618e45424145c7a3c813a77594b5 347 Pfam PF00155 Aminotransferase class I and II 28 341 1.8E-56 T 01-11-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 AFULGI_00022660 0f8a618e45424145c7a3c813a77594b5 347 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 6 344 6.7E-96 T 01-11-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 AFULGI_00022660 0f8a618e45424145c7a3c813a77594b5 347 SUPERFAMILY SSF53383 21 342 6.99E-78 T 01-11-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFULGI_00001580 a626ca843f6b1a000f73f19b90e68b2e 176 Pfam PF02613 Nitrate reductase delta subunit 73 136 2.7E-11 T 01-11-2018 IPR020945 DMSO/Nitrate reductase chaperone AFULGI_00001580 a626ca843f6b1a000f73f19b90e68b2e 176 Gene3D G3DSA:1.10.3480.10 2 176 2.0E-106 T 01-11-2018 AFULGI_00001580 a626ca843f6b1a000f73f19b90e68b2e 176 SUPERFAMILY SSF89155 5 161 2.09E-30 T 01-11-2018 IPR036411 TorD-like superfamily AFULGI_00005410 d7dd659820ed778527aab8b3602626ef 407 SMART SM00849 14 184 2.0E-20 T 01-11-2018 IPR001279 Metallo-beta-lactamase AFULGI_00005410 d7dd659820ed778527aab8b3602626ef 407 Pfam PF00753 Metallo-beta-lactamase superfamily 23 162 3.5E-8 T 01-11-2018 IPR001279 Metallo-beta-lactamase AFULGI_00005410 d7dd659820ed778527aab8b3602626ef 407 SMART SM01027 218 325 2.8E-24 T 01-11-2018 IPR022712 Beta-Casp domain AFULGI_00005410 d7dd659820ed778527aab8b3602626ef 407 Gene3D G3DSA:3.40.50.10890 186 349 1.8E-94 T 01-11-2018 AFULGI_00005410 d7dd659820ed778527aab8b3602626ef 407 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 338 399 1.4E-14 T 01-11-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain AFULGI_00005410 d7dd659820ed778527aab8b3602626ef 407 Pfam PF10996 Beta-Casp domain 218 323 2.1E-11 T 01-11-2018 IPR022712 Beta-Casp domain AFULGI_00005410 d7dd659820ed778527aab8b3602626ef 407 SUPERFAMILY SSF56281 3 406 3.9E-100 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFULGI_00005410 d7dd659820ed778527aab8b3602626ef 407 Gene3D G3DSA:3.60.15.10 7 380 1.8E-94 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFULGI_00006480 b242750c8395859b8d48edb80698d815 202 PIRSF PIRSF004857 1 200 6.4E-76 T 01-11-2018 IPR011375 MfnE family KEGG: 00680+2.7.4.31|MetaCyc: PWY-5254 AFULGI_00006480 b242750c8395859b8d48edb80698d815 202 Gene3D G3DSA:3.40.1160.10 1 198 1.7E-14 T 01-11-2018 IPR036393 Acetylglutamate kinase-like superfamily AFULGI_00006480 b242750c8395859b8d48edb80698d815 202 SUPERFAMILY SSF53633 1 200 2.51E-15 T 01-11-2018 IPR036393 Acetylglutamate kinase-like superfamily AFULGI_00011730 21513cdc4b32a9ba4cec6f375b75041f 85 Gene3D G3DSA:3.40.50.1010 1 83 4.1E-8 T 01-11-2018 AFULGI_00011730 21513cdc4b32a9ba4cec6f375b75041f 85 SUPERFAMILY SSF88723 16 79 2.78E-12 T 01-11-2018 IPR029060 PIN-like domain superfamily AFULGI_00011730 21513cdc4b32a9ba4cec6f375b75041f 85 Pfam PF01850 PIN domain 13 79 5.3E-18 T 01-11-2018 IPR002716 PIN domain AFULGI_00014580 22429d0ffa9f71d3ad4a91cae4c043af 391 Hamap MF_02096 DNA repair protein. 1 388 35.976 T 01-11-2018 IPR033167 Archaeal Nre GO:0006281 AFULGI_00014580 22429d0ffa9f71d3ad4a91cae4c043af 391 Pfam PF04894 Archaeal Nre, N-terminal 14 276 1.2E-94 T 01-11-2018 IPR006978 Archaeal Nre, N-terminal AFULGI_00014580 22429d0ffa9f71d3ad4a91cae4c043af 391 Pfam PF04895 Archaeal Nre, C-terminal 287 376 1.5E-30 T 01-11-2018 IPR006979 Archaeal Nre, C-terminal AFULGI_00001630 a14e266a71ce7509b71ffe944c780c55 436 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 105 253 3.6E-30 T 01-11-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AFULGI_00001630 a14e266a71ce7509b71ffe944c780c55 436 SUPERFAMILY SSF56014 103 261 2.75E-28 T 01-11-2018 AFULGI_00001630 a14e266a71ce7509b71ffe944c780c55 436 Gene3D G3DSA:3.30.413.10 103 264 6.8E-74 T 01-11-2018 AFULGI_00001630 a14e266a71ce7509b71ffe944c780c55 436 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 374 390 - T 01-11-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AFULGI_00001630 a14e266a71ce7509b71ffe944c780c55 436 SUPERFAMILY SSF56014 340 410 2.09E-9 T 01-11-2018 AFULGI_00001630 a14e266a71ce7509b71ffe944c780c55 436 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 28 87 8.9E-20 T 01-11-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AFULGI_00001630 a14e266a71ce7509b71ffe944c780c55 436 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 272 332 2.2E-13 T 01-11-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AFULGI_00001630 a14e266a71ce7509b71ffe944c780c55 436 SUPERFAMILY SSF55124 272 331 2.43E-10 T 01-11-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AFULGI_00001630 a14e266a71ce7509b71ffe944c780c55 436 SUPERFAMILY SSF55124 10 92 1.74E-21 T 01-11-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AFULGI_00001630 a14e266a71ce7509b71ffe944c780c55 436 Gene3D G3DSA:3.30.413.10 324 430 1.3E-5 T 01-11-2018 AFULGI_00001630 a14e266a71ce7509b71ffe944c780c55 436 Gene3D G3DSA:3.90.480.10 31 322 6.8E-74 T 01-11-2018 AFULGI_00002230 e5000811017c96aed55d22bc59f47da1 325 SMART SM00359 237 311 7.0E-23 T 01-11-2018 IPR002478 PUA domain GO:0003723 AFULGI_00002230 e5000811017c96aed55d22bc59f47da1 325 Hamap MF_01081 Probable tRNA pseudouridine synthase B [truB]. 27 311 52.416 T 01-11-2018 IPR026326 Probable tRNA pseudouridine synthase B, archaeal GO:0006396 AFULGI_00002230 e5000811017c96aed55d22bc59f47da1 325 Gene3D G3DSA:2.30.130.70 11 318 1.3E-142 T 01-11-2018 AFULGI_00002230 e5000811017c96aed55d22bc59f47da1 325 TIGRFAM TIGR00425 CBF5: putative rRNA pseudouridine synthase 2 321 7.3E-174 T 01-11-2018 IPR004802 tRNA pseudouridine synthase B family GO:0006396 Reactome: R-HSA-171319|Reactome: R-HSA-6790901 AFULGI_00002230 e5000811017c96aed55d22bc59f47da1 325 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 235 303 2.5E-7 T 01-11-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 AFULGI_00002230 e5000811017c96aed55d22bc59f47da1 325 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 54 167 7.6E-24 T 01-11-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 AFULGI_00002230 e5000811017c96aed55d22bc59f47da1 325 Gene3D G3DSA:3.30.2350.10 27 229 1.3E-142 T 01-11-2018 AFULGI_00002230 e5000811017c96aed55d22bc59f47da1 325 Pfam PF01472 PUA domain 237 309 3.0E-20 T 01-11-2018 IPR002478 PUA domain GO:0003723 AFULGI_00002230 e5000811017c96aed55d22bc59f47da1 325 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 168 232 1.1E-25 T 01-11-2018 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 AFULGI_00002230 e5000811017c96aed55d22bc59f47da1 325 Pfam PF08068 DKCLD (NUC011) domain 4 50 4.2E-17 T 01-11-2018 IPR012960 Dyskerin-like Reactome: R-HSA-171319|Reactome: R-HSA-6790901 AFULGI_00002230 e5000811017c96aed55d22bc59f47da1 325 SUPERFAMILY SSF88697 236 318 7.73E-22 T 01-11-2018 IPR015947 PUA-like superfamily AFULGI_00002230 e5000811017c96aed55d22bc59f47da1 325 SMART SM01136 2 50 6.7E-24 T 01-11-2018 IPR012960 Dyskerin-like Reactome: R-HSA-171319|Reactome: R-HSA-6790901 AFULGI_00002230 e5000811017c96aed55d22bc59f47da1 325 SUPERFAMILY SSF55120 4 232 8.63E-74 T 01-11-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFULGI_00012860 95421804d11424a89ee70db562351f12 491 Pfam PF00571 CBS domain 375 428 7.1E-14 T 01-11-2018 IPR000644 CBS domain AFULGI_00012860 95421804d11424a89ee70db562351f12 491 Pfam PF00571 CBS domain 435 489 2.7E-15 T 01-11-2018 IPR000644 CBS domain AFULGI_00012860 95421804d11424a89ee70db562351f12 491 SMART SM00116 442 490 6.8E-13 T 01-11-2018 IPR000644 CBS domain AFULGI_00012860 95421804d11424a89ee70db562351f12 491 SMART SM00116 381 428 2.1E-13 T 01-11-2018 IPR000644 CBS domain AFULGI_00012860 95421804d11424a89ee70db562351f12 491 ProDom PD011569 METAL-BINDING IRON IRON-SULFUR 4FE-4S FERREDOXIN OXIDOREDUCTASE DOMAIN ELECTRON METHANOGENESIS A 14 269 7.0E-151 T 01-11-2018 IPR002708 Homocysteine biosynthesis enzyme, sulfur-incorporation AFULGI_00012860 95421804d11424a89ee70db562351f12 491 Gene3D G3DSA:3.10.580.10 429 491 7.1E-17 T 01-11-2018 AFULGI_00012860 95421804d11424a89ee70db562351f12 491 PIRSF PIRSF004698 1 491 5.9E-267 T 01-11-2018 IPR016426 Uncharacterised conserved protein UCP004698, CBS-type AFULGI_00012860 95421804d11424a89ee70db562351f12 491 Gene3D G3DSA:3.10.580.10 335 428 1.3E-16 T 01-11-2018 AFULGI_00012860 95421804d11424a89ee70db562351f12 491 Pfam PF01837 Homocysteine biosynthesis enzyme, sulfur-incorporation 17 351 1.4E-144 T 01-11-2018 IPR002708 Homocysteine biosynthesis enzyme, sulfur-incorporation AFULGI_00012860 95421804d11424a89ee70db562351f12 491 SUPERFAMILY SSF54631 372 490 2.99E-32 T 01-11-2018 AFULGI_00009690 82ff24a2ec7a5aaa7442377a21c7bab8 435 SMART SM00091 127 193 0.72 T 01-11-2018 IPR000014 PAS domain AFULGI_00009690 82ff24a2ec7a5aaa7442377a21c7bab8 435 SMART SM00091 9 75 5.7E-8 T 01-11-2018 IPR000014 PAS domain AFULGI_00009690 82ff24a2ec7a5aaa7442377a21c7bab8 435 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 332 431 4.1E-17 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFULGI_00009690 82ff24a2ec7a5aaa7442377a21c7bab8 435 Gene3D G3DSA:3.30.565.10 299 433 2.1E-25 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFULGI_00009690 82ff24a2ec7a5aaa7442377a21c7bab8 435 PRINTS PR00344 Bacterial sensor protein C-terminal signature 395 413 1.2E-9 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFULGI_00009690 82ff24a2ec7a5aaa7442377a21c7bab8 435 PRINTS PR00344 Bacterial sensor protein C-terminal signature 418 431 1.2E-9 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFULGI_00009690 82ff24a2ec7a5aaa7442377a21c7bab8 435 PRINTS PR00344 Bacterial sensor protein C-terminal signature 365 379 1.2E-9 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFULGI_00009690 82ff24a2ec7a5aaa7442377a21c7bab8 435 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 7 129 3.5E-20 T 01-11-2018 IPR000014 PAS domain AFULGI_00009690 82ff24a2ec7a5aaa7442377a21c7bab8 435 Gene3D G3DSA:3.30.450.20 9 134 3.0E-22 T 01-11-2018 AFULGI_00009690 82ff24a2ec7a5aaa7442377a21c7bab8 435 SUPERFAMILY SSF55785 14 124 6.13E-18 T 01-11-2018 IPR035965 PAS domain superfamily AFULGI_00009690 82ff24a2ec7a5aaa7442377a21c7bab8 435 SUPERFAMILY SSF55874 316 430 2.36E-24 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFULGI_00009690 82ff24a2ec7a5aaa7442377a21c7bab8 435 Pfam PF08447 PAS fold 33 103 4.9E-10 T 01-11-2018 IPR013655 PAS fold-3 GO:0005515 AFULGI_00009690 82ff24a2ec7a5aaa7442377a21c7bab8 435 Gene3D G3DSA:3.30.450.20 135 236 1.2E-8 T 01-11-2018 AFULGI_00009690 82ff24a2ec7a5aaa7442377a21c7bab8 435 Pfam PF13188 PAS domain 129 167 1.8E-5 T 01-11-2018 IPR000014 PAS domain AFULGI_00009690 82ff24a2ec7a5aaa7442377a21c7bab8 435 SMART SM00387 329 434 1.5E-24 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFULGI_00009690 82ff24a2ec7a5aaa7442377a21c7bab8 435 SUPERFAMILY SSF55785 121 220 6.11E-12 T 01-11-2018 IPR035965 PAS domain superfamily AFULGI_00008570 470a848242c80646a3eb08c5bc5c8c8b 88 Hamap MF_00216 Translation initiation factor 1A [eif1a]. 1 87 27.324 T 01-11-2018 IPR001253 Translation initiation factor 1A (eIF-1A) GO:0003743|GO:0006413 AFULGI_00008570 470a848242c80646a3eb08c5bc5c8c8b 88 SMART SM00652 5 87 9.1E-49 T 01-11-2018 IPR001253 Translation initiation factor 1A (eIF-1A) GO:0003743|GO:0006413 AFULGI_00008570 470a848242c80646a3eb08c5bc5c8c8b 88 ProDom PD005579 INITIATION FACTOR TRANSLATION 1A BIOSYNTHESIS EUKARYOTIC EIF-1A AIF-1A EIF-4C 1A 30 87 4.0E-27 T 01-11-2018 IPR001253 Translation initiation factor 1A (eIF-1A) GO:0003743|GO:0006413 AFULGI_00008570 470a848242c80646a3eb08c5bc5c8c8b 88 Gene3D G3DSA:2.40.50.140 1 87 1.7E-35 T 01-11-2018 AFULGI_00008570 470a848242c80646a3eb08c5bc5c8c8b 88 ProSitePatterns PS01262 Eukaryotic initiation factor 1A signature. 18 40 - T 01-11-2018 IPR018104 Translation initiation factor 1A (eIF-1A), conserved site GO:0003743|GO:0006413 AFULGI_00008570 470a848242c80646a3eb08c5bc5c8c8b 88 Pfam PF01176 Translation initiation factor 1A / IF-1 10 71 1.0E-25 T 01-11-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 AFULGI_00008570 470a848242c80646a3eb08c5bc5c8c8b 88 TIGRFAM TIGR00523 eIF-1A: translation initiation factor eIF-1A 1 88 7.5E-48 T 01-11-2018 IPR001253 Translation initiation factor 1A (eIF-1A) GO:0003743|GO:0006413 AFULGI_00008570 470a848242c80646a3eb08c5bc5c8c8b 88 SUPERFAMILY SSF50249 2 86 4.0E-35 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold AFULGI_00026020 ccd20881448df483f113b2cf05002893 286 Gene3D G3DSA:3.40.50.20 6 105 2.5E-5 T 01-11-2018 AFULGI_00026020 ccd20881448df483f113b2cf05002893 286 Gene3D G3DSA:3.30.470.20 173 285 1.8E-21 T 01-11-2018 AFULGI_00026020 ccd20881448df483f113b2cf05002893 286 SUPERFAMILY SSF56059 81 285 6.01E-37 T 01-11-2018 AFULGI_00026020 ccd20881448df483f113b2cf05002893 286 Gene3D G3DSA:3.30.1490.20 106 171 3.8E-7 T 01-11-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 AFULGI_00026020 ccd20881448df483f113b2cf05002893 286 Pfam PF08443 RimK-like ATP-grasp domain 89 283 4.3E-14 T 01-11-2018 IPR013651 ATP-grasp fold, RimK-type Reactome: R-HSA-70614 AFULGI_00022760 2b8e05c6883391c210ef4db591a5dd23 137 SUPERFAMILY SSF88723 7 134 2.47E-19 T 01-11-2018 IPR029060 PIN-like domain superfamily AFULGI_00022760 2b8e05c6883391c210ef4db591a5dd23 137 SMART SM00670 5 128 1.5E-19 T 01-11-2018 IPR002716 PIN domain AFULGI_00022760 2b8e05c6883391c210ef4db591a5dd23 137 Gene3D G3DSA:3.40.50.1010 6 135 1.1E-15 T 01-11-2018 AFULGI_00022760 2b8e05c6883391c210ef4db591a5dd23 137 Pfam PF01850 PIN domain 8 131 4.7E-22 T 01-11-2018 IPR002716 PIN domain AFULGI_00020560 c0ea308a7037bb597c2ecacf853f2b87 258 Gene3D G3DSA:1.10.510.10 157 258 1.3E-28 T 01-11-2018 AFULGI_00020560 c0ea308a7037bb597c2ecacf853f2b87 258 Pfam PF01163 RIO1 family 62 250 2.0E-64 T 01-11-2018 AFULGI_00020560 c0ea308a7037bb597c2ecacf853f2b87 258 SUPERFAMILY SSF56112 52 240 1.5E-22 T 01-11-2018 IPR011009 Protein kinase-like domain superfamily AFULGI_00020560 c0ea308a7037bb597c2ecacf853f2b87 258 Gene3D G3DSA:3.30.200.20 48 151 2.9E-11 T 01-11-2018 AFULGI_00020560 c0ea308a7037bb597c2ecacf853f2b87 258 SMART SM00090 20 257 5.7E-135 T 01-11-2018 IPR000687 RIO kinase GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 AFULGI_00020560 c0ea308a7037bb597c2ecacf853f2b87 258 ProSitePatterns PS01245 RIO1/ZK632.3/MJ0444 family signature. 192 203 - T 01-11-2018 IPR018935 RIO kinase, conserved site GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 AFULGI_00009520 1950c2b1bf3cf20e0319f9df1821c75b 328 SUPERFAMILY SSF46548 24 102 2.79E-10 T 01-11-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 AFULGI_00009520 1950c2b1bf3cf20e0319f9df1821c75b 328 Pfam PF13183 4Fe-4S dicluster domain 35 95 1.5E-6 T 01-11-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFULGI_00009520 1950c2b1bf3cf20e0319f9df1821c75b 328 Pfam PF02754 Cysteine-rich domain 233 316 4.2E-10 T 01-11-2018 IPR004017 Cysteine-rich domain AFULGI_00009520 1950c2b1bf3cf20e0319f9df1821c75b 328 Pfam PF02754 Cysteine-rich domain 134 210 4.0E-5 T 01-11-2018 IPR004017 Cysteine-rich domain AFULGI_00011720 d79d37893eaf19488b19b123a0bb375f 69 Pfam PF15919 HicB_like antitoxin of bacterial toxin-antitoxin system 3 57 1.1E-12 T 01-11-2018 IPR031807 HicB-like antitoxin of toxin-antitoxin system AFULGI_00011720 d79d37893eaf19488b19b123a0bb375f 69 SUPERFAMILY SSF143100 1 58 9.42E-20 T 01-11-2018 IPR035069 TTHA1013/TTHA0281-like AFULGI_00011720 d79d37893eaf19488b19b123a0bb375f 69 Gene3D G3DSA:3.30.160.250 1 65 5.3E-27 T 01-11-2018 AFULGI_00012110 bfcbe3bd7952aa48ecc471d85fcfda92 107 Gene3D G3DSA:3.30.70.330 1 101 6.0E-34 T 01-11-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily AFULGI_00012110 bfcbe3bd7952aa48ecc471d85fcfda92 107 ProDom PD006052 RIBOSOMAL S24 40S RIBONUCLEOPROTEIN S24E 30S S24 CDNA RIKEN ACETYLATION 11 79 2.0E-34 T 01-11-2018 IPR001976 Ribosomal protein S24e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00012110 bfcbe3bd7952aa48ecc471d85fcfda92 107 SUPERFAMILY SSF54189 1 101 7.91E-31 T 01-11-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFULGI_00012110 bfcbe3bd7952aa48ecc471d85fcfda92 107 Pfam PF01282 Ribosomal protein S24e 24 96 1.1E-25 T 01-11-2018 IPR001976 Ribosomal protein S24e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00012110 bfcbe3bd7952aa48ecc471d85fcfda92 107 ProSitePatterns PS00529 Ribosomal protein S24e signature. 59 81 - T 01-11-2018 IPR018098 Ribosomal S24e conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00012110 bfcbe3bd7952aa48ecc471d85fcfda92 107 Hamap MF_00545 30S ribosomal protein S24e [rps24e]. 1 99 20.571 T 01-11-2018 IPR001976 Ribosomal protein S24e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00008580 397634bbe747891da298b7d6d73c8506 306 Pfam PF06626 Protein of unknown function (DUF1152) 16 302 9.0E-101 T 01-11-2018 IPR010581 Protein of unknown function DUF1152 AFULGI_00008580 397634bbe747891da298b7d6d73c8506 306 PIRSF PIRSF029122 7 306 3.4E-119 T 01-11-2018 IPR010581 Protein of unknown function DUF1152 AFULGI_00014080 5b6a074a838cf56c09e052fc8550ddda 733 SMART SM01072 109 171 4.2E-20 T 01-11-2018 IPR004201 CDC48, domain 2 AFULGI_00014080 5b6a074a838cf56c09e052fc8550ddda 733 ProSitePatterns PS00674 AAA-protein family signature. 593 611 - T 01-11-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 AFULGI_00014080 5b6a074a838cf56c09e052fc8550ddda 733 SMART SM00382 488 625 1.4E-24 T 01-11-2018 IPR003593 AAA+ ATPase domain AFULGI_00014080 5b6a074a838cf56c09e052fc8550ddda 733 SMART SM00382 215 351 1.3E-25 T 01-11-2018 IPR003593 AAA+ ATPase domain AFULGI_00014080 5b6a074a838cf56c09e052fc8550ddda 733 Pfam PF02359 Cell division protein 48 (CDC48), N-terminal domain 10 93 4.6E-31 T 01-11-2018 IPR003338 CDC48, N-terminal subdomain AFULGI_00014080 5b6a074a838cf56c09e052fc8550ddda 733 SUPERFAMILY SSF54585 95 184 4.9E-21 T 01-11-2018 IPR029067 CDC48 domain 2-like superfamily AFULGI_00014080 5b6a074a838cf56c09e052fc8550ddda 733 Gene3D G3DSA:1.10.8.60 350 445 1.4E-35 T 01-11-2018 AFULGI_00014080 5b6a074a838cf56c09e052fc8550ddda 733 SMART SM01073 10 94 2.0E-40 T 01-11-2018 IPR003338 CDC48, N-terminal subdomain AFULGI_00014080 5b6a074a838cf56c09e052fc8550ddda 733 Gene3D G3DSA:3.40.50.300 450 722 9.5E-113 T 01-11-2018 AFULGI_00014080 5b6a074a838cf56c09e052fc8550ddda 733 Gene3D G3DSA:3.10.330.10 114 181 1.8E-6 T 01-11-2018 AFULGI_00014080 5b6a074a838cf56c09e052fc8550ddda 733 Pfam PF02933 Cell division protein 48 (CDC48), domain 2 112 171 3.5E-18 T 01-11-2018 IPR004201 CDC48, domain 2 AFULGI_00014080 5b6a074a838cf56c09e052fc8550ddda 733 SUPERFAMILY SSF52540 177 444 1.54E-78 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00014080 5b6a074a838cf56c09e052fc8550ddda 733 TIGRFAM TIGR01243 CDC48: AAA family ATPase, CDC48 subfamily 9 730 0.0 T 01-11-2018 IPR005938 AAA ATPase, CDC48 family GO:0016787 Reactome: R-HSA-110320|Reactome: R-HSA-3371511|Reactome: R-HSA-382556|Reactome: R-HSA-532668|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5678895|Reactome: R-HSA-5689877|Reactome: R-HSA-5689896|Reactome: R-HSA-6798695|Reactome: R-HSA-8866654|Reactome: R-HSA-8876725 AFULGI_00014080 5b6a074a838cf56c09e052fc8550ddda 733 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 219 348 1.1E-50 T 01-11-2018 IPR003959 ATPase, AAA-type, core GO:0005524 AFULGI_00014080 5b6a074a838cf56c09e052fc8550ddda 733 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 492 622 8.6E-50 T 01-11-2018 IPR003959 ATPase, AAA-type, core GO:0005524 AFULGI_00014080 5b6a074a838cf56c09e052fc8550ddda 733 Gene3D G3DSA:3.40.50.300 182 348 2.0E-69 T 01-11-2018 AFULGI_00014080 5b6a074a838cf56c09e052fc8550ddda 733 Gene3D G3DSA:2.40.40.20 3 94 4.7E-35 T 01-11-2018 AFULGI_00014080 5b6a074a838cf56c09e052fc8550ddda 733 Pfam PF09336 Vps4 C terminal oligomerisation domain 690 728 3.4E-6 T 01-11-2018 IPR015415 Vps4 oligomerisation, C-terminal AFULGI_00014080 5b6a074a838cf56c09e052fc8550ddda 733 ProSitePatterns PS00674 AAA-protein family signature. 319 337 - T 01-11-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 AFULGI_00014080 5b6a074a838cf56c09e052fc8550ddda 733 SUPERFAMILY SSF50692 5 92 3.25E-30 T 01-11-2018 IPR009010 Aspartate decarboxylase-like domain superfamily AFULGI_00014080 5b6a074a838cf56c09e052fc8550ddda 733 SUPERFAMILY SSF52540 450 726 7.65E-82 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00014080 5b6a074a838cf56c09e052fc8550ddda 733 Gene3D G3DSA:1.10.8.60 624 709 9.5E-113 T 01-11-2018 AFULGI_00013080 38e16350de2dfa370730ac64b38bfdb5 213 TIGRFAM TIGR01915 npdG: NADPH-dependent F420 reductase 1 212 1.3E-68 T 01-11-2018 IPR010185 NADPH-dependent F420 reductase GO:0006740|GO:0016651|GO:0050661|GO:0055114|GO:0070967 AFULGI_00013080 38e16350de2dfa370730ac64b38bfdb5 213 SUPERFAMILY SSF51735 1 204 6.5E-41 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily AFULGI_00013080 38e16350de2dfa370730ac64b38bfdb5 213 Gene3D G3DSA:3.40.50.720 1 213 4.1E-52 T 01-11-2018 AFULGI_00013080 38e16350de2dfa370730ac64b38bfdb5 213 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 2 99 2.0E-21 T 01-11-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal AFULGI_00021890 c41956eef22d04c5a23a270dd057c732 562 Pfam PF07969 Amidohydrolase family 45 501 1.1E-94 T 01-11-2018 IPR013108 Amidohydrolase 3 AFULGI_00021890 c41956eef22d04c5a23a270dd057c732 562 Gene3D G3DSA:2.30.40.10 3 83 5.1E-13 T 01-11-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 AFULGI_00021890 c41956eef22d04c5a23a270dd057c732 562 SUPERFAMILY SSF51556 57 454 2.53E-19 T 01-11-2018 IPR032466 Metal-dependent hydrolase AFULGI_00021890 c41956eef22d04c5a23a270dd057c732 562 TIGRFAM TIGR03121 one_C_dehyd_A: formylmethanofuran dehydrogenase subunit A 5 557 2.4E-253 T 01-11-2018 IPR012027 Formylmethanofuran dehydrogenase, subunit A AFULGI_00021890 c41956eef22d04c5a23a270dd057c732 562 Gene3D G3DSA:2.30.40.10 455 509 5.7E-10 T 01-11-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 AFULGI_00021890 c41956eef22d04c5a23a270dd057c732 562 SUPERFAMILY SSF51338 385 517 3.65E-32 T 01-11-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 AFULGI_00021890 c41956eef22d04c5a23a270dd057c732 562 PIRSF PIRSF006453 2 562 9.5E-242 T 01-11-2018 IPR012027 Formylmethanofuran dehydrogenase, subunit A AFULGI_00021890 c41956eef22d04c5a23a270dd057c732 562 SUPERFAMILY SSF51338 4 70 3.57E-14 T 01-11-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 AFULGI_00021890 c41956eef22d04c5a23a270dd057c732 562 Gene3D G3DSA:3.20.20.140 432 454 5.7E-10 T 01-11-2018 AFULGI_00019260 ac756a63c3b3195285ce54c5279bed39 411 TIGRFAM TIGR00094 tRNA_TruD_broad: tRNA pseudouridine synthase, TruD family 1 410 2.5E-154 T 01-11-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFULGI_00019260 ac756a63c3b3195285ce54c5279bed39 411 Hamap MF_01082 tRNA pseudouridine synthase D [truD]. 6 410 30.485 T 01-11-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFULGI_00019260 ac756a63c3b3195285ce54c5279bed39 411 SUPERFAMILY SSF55120 3 408 7.77E-88 T 01-11-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFULGI_00019260 ac756a63c3b3195285ce54c5279bed39 411 PIRSF PIRSF037016 385 411 7.5E-4 T 01-11-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFULGI_00019260 ac756a63c3b3195285ce54c5279bed39 411 PIRSF PIRSF037016 1 41 11.0 T 01-11-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFULGI_00019260 ac756a63c3b3195285ce54c5279bed39 411 PIRSF PIRSF037016 34 384 1.5E-74 T 01-11-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFULGI_00019260 ac756a63c3b3195285ce54c5279bed39 411 Gene3D G3DSA:3.30.70.3160 39 124 2.9E-118 T 01-11-2018 AFULGI_00019260 ac756a63c3b3195285ce54c5279bed39 411 ProSitePatterns PS01268 Uncharacterized protein family UPF0024 signature. 78 91 - T 01-11-2018 IPR020119 Pseudouridine synthase TruD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 Reactome: R-HSA-6782315 AFULGI_00019260 ac756a63c3b3195285ce54c5279bed39 411 Gene3D G3DSA:3.30.2350.20 125 404 2.9E-118 T 01-11-2018 AFULGI_00019260 ac756a63c3b3195285ce54c5279bed39 411 Gene3D G3DSA:1.10.1510.30 167 254 2.9E-118 T 01-11-2018 AFULGI_00019260 ac756a63c3b3195285ce54c5279bed39 411 Pfam PF01142 tRNA pseudouridine synthase D (TruD) 5 405 1.1E-140 T 01-11-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFULGI_00008100 e3b9e29d20acb0eaf1eaf26f2421b999 240 Pfam PF02361 Cobalt transport protein 9 211 1.9E-52 T 01-11-2018 IPR003339 ABC/ECF transporter, transmembrane component AFULGI_00008100 e3b9e29d20acb0eaf1eaf26f2421b999 240 TIGRFAM TIGR02454 ECF_T_CbiQ: cobalt ECF transporter T component CbiQ 16 207 5.7E-47 T 01-11-2018 IPR012809 Cobalt ECF transporter T component CbiQ GO:0005887|GO:0006824|GO:0043190 AFULGI_00009740 040641c865007a50d8a618c6e1aa437c 461 Pfam PF03241 4-hydroxyphenylacetate 3-hydroxylase C terminal 273 459 1.3E-41 T 01-11-2018 IPR024719 HpaB/PvcC/4-BUDH C-terminal AFULGI_00009740 040641c865007a50d8a618c6e1aa437c 461 Gene3D G3DSA:1.10.3140.10 1 137 1.5E-35 T 01-11-2018 AFULGI_00009740 040641c865007a50d8a618c6e1aa437c 461 Pfam PF11794 4-hydroxyphenylacetate 3-hydroxylase N terminal 6 265 8.0E-80 T 01-11-2018 IPR024674 HpaB/PvcC/4-BUDH N-terminal AFULGI_00009740 040641c865007a50d8a618c6e1aa437c 461 SUPERFAMILY SSF47203 256 460 1.07E-46 T 01-11-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 AFULGI_00009740 040641c865007a50d8a618c6e1aa437c 461 Gene3D G3DSA:2.40.110.10 139 266 4.8E-38 T 01-11-2018 AFULGI_00009740 040641c865007a50d8a618c6e1aa437c 461 Gene3D G3DSA:1.20.140.10 270 461 2.5E-44 T 01-11-2018 AFULGI_00009740 040641c865007a50d8a618c6e1aa437c 461 SUPERFAMILY SSF56645 1 265 3.66E-66 T 01-11-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 AFULGI_00009740 040641c865007a50d8a618c6e1aa437c 461 PIRSF PIRSF000331 1 461 1.0E-143 T 01-11-2018 IPR004925 HpaB/PvcC/4-BUDH AFULGI_00014370 58bc1e13cdce17a78fcbd9bc53eebecf 197 SUPERFAMILY SSF52540 6 172 5.43E-26 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00014370 58bc1e13cdce17a78fcbd9bc53eebecf 197 Pfam PF01926 50S ribosome-binding GTPase 5 133 3.4E-16 T 01-11-2018 IPR006073 GTP binding domain GO:0005525 AFULGI_00014370 58bc1e13cdce17a78fcbd9bc53eebecf 197 Gene3D G3DSA:3.40.50.300 4 186 2.0E-34 T 01-11-2018 AFULGI_00014370 58bc1e13cdce17a78fcbd9bc53eebecf 197 Hamap MF_00321 Probable GTP-binding protein EngB [engB]. 1 184 23.13 T 01-11-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 AFULGI_00014720 d906a31e206989c9a83cd8b98e49ab8c 136 SMART SM00226 2 126 4.4E-52 T 01-11-2018 IPR023485 Phosphotyrosine protein phosphatase I AFULGI_00014720 d906a31e206989c9a83cd8b98e49ab8c 136 Gene3D G3DSA:3.40.50.2300 3 126 4.9E-47 T 01-11-2018 AFULGI_00014720 d906a31e206989c9a83cd8b98e49ab8c 136 SUPERFAMILY SSF52788 3 124 9.81E-33 T 01-11-2018 IPR036196 Phosphotyrosine protein phosphatase I superfamily AFULGI_00014720 d906a31e206989c9a83cd8b98e49ab8c 136 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 4 124 1.7E-23 T 01-11-2018 IPR023485 Phosphotyrosine protein phosphatase I AFULGI_00026180 7d8551b458bc106bb4516ae16f38d451 145 Gene3D G3DSA:3.30.1440.10 1 145 3.8E-57 T 01-11-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00026180 7d8551b458bc106bb4516ae16f38d451 145 Pfam PF01877 RNA binding 7 123 2.1E-39 T 01-11-2018 IPR002739 Uncharacterised protein family UPF0201 AFULGI_00026180 7d8551b458bc106bb4516ae16f38d451 145 SUPERFAMILY SSF55282 5 141 3.24E-41 T 01-11-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00000320 b35931dd423dae2d9d8952a88110f5d2 383 Pfam PF00108 Thiolase, N-terminal domain 4 214 1.9E-18 T 01-11-2018 IPR020616 Thiolase, N-terminal GO:0016747 AFULGI_00000320 b35931dd423dae2d9d8952a88110f5d2 383 SUPERFAMILY SSF53901 243 370 5.35E-25 T 01-11-2018 IPR016039 Thiolase-like GO:0003824 AFULGI_00000320 b35931dd423dae2d9d8952a88110f5d2 383 SUPERFAMILY SSF53901 1 220 6.13E-42 T 01-11-2018 IPR016039 Thiolase-like GO:0003824 AFULGI_00000320 b35931dd423dae2d9d8952a88110f5d2 383 PIRSF PIRSF000429 1 382 5.9E-85 T 01-11-2018 IPR002155 Thiolase GO:0016747 AFULGI_00000320 b35931dd423dae2d9d8952a88110f5d2 383 Pfam PF02803 Thiolase, C-terminal domain 256 349 1.7E-6 T 01-11-2018 IPR020617 Thiolase, C-terminal GO:0016747 AFULGI_00000320 b35931dd423dae2d9d8952a88110f5d2 383 Gene3D G3DSA:3.40.47.10 3 382 8.9E-114 T 01-11-2018 IPR016039 Thiolase-like GO:0003824 AFULGI_00023470 da6550c89196adeedd360f624ad0fc63 340 ProSitePatterns PS00501 Signal peptidases I serine active site. 35 42 - T 01-11-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 AFULGI_00023470 da6550c89196adeedd360f624ad0fc63 340 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 33 48 2.6E-7 T 01-11-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 AFULGI_00023470 da6550c89196adeedd360f624ad0fc63 340 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 83 94 2.6E-7 T 01-11-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 AFULGI_00023470 da6550c89196adeedd360f624ad0fc63 340 SUPERFAMILY SSF51306 32 138 2.49E-12 T 01-11-2018 IPR036286 LexA/Signal peptidase-like superfamily AFULGI_00023470 da6550c89196adeedd360f624ad0fc63 340 Gene3D G3DSA:2.10.109.10 34 115 1.0E-5 T 01-11-2018 AFULGI_00023470 da6550c89196adeedd360f624ad0fc63 340 TIGRFAM TIGR02228 sigpep_I_arch: signal peptidase I 7 112 2.3E-17 T 01-11-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 AFULGI_00023470 da6550c89196adeedd360f624ad0fc63 340 Pfam PF00717 Peptidase S24-like 32 88 1.5E-13 T 01-11-2018 IPR015927 Peptidase S24/S26A/S26B/S26C AFULGI_00021950 b297b5c5ecad8de7cdfb877ac26a98dc 316 Pfam PF02289 Cyclohydrolase (MCH) 3 310 1.5E-137 T 01-11-2018 IPR003209 Methenyltetrahydromethanopterin cyclohydrolase GO:0006730|GO:0018759 KEGG: 00680+3.5.4.27|MetaCyc: PWY-1723|MetaCyc: PWY-7784 AFULGI_00021950 b297b5c5ecad8de7cdfb877ac26a98dc 316 Hamap MF_00486 Methenyltetrahydromethanopterin cyclohydrolase [mch]. 1 314 156.477 T 01-11-2018 IPR003209 Methenyltetrahydromethanopterin cyclohydrolase GO:0006730|GO:0018759 KEGG: 00680+3.5.4.27|MetaCyc: PWY-1723|MetaCyc: PWY-7784 AFULGI_00021950 b297b5c5ecad8de7cdfb877ac26a98dc 316 Gene3D G3DSA:3.10.340.11 2 169 2.1E-141 T 01-11-2018 AFULGI_00021950 b297b5c5ecad8de7cdfb877ac26a98dc 316 TIGRFAM TIGR03120 one_C_mch: methenyltetrahydromethanopterin cyclohydrolase 3 311 4.0E-149 T 01-11-2018 IPR003209 Methenyltetrahydromethanopterin cyclohydrolase GO:0006730|GO:0018759 KEGG: 00680+3.5.4.27|MetaCyc: PWY-1723|MetaCyc: PWY-7784 AFULGI_00021950 b297b5c5ecad8de7cdfb877ac26a98dc 316 Gene3D G3DSA:3.30.1030.10 45 306 2.1E-141 T 01-11-2018 AFULGI_00021950 b297b5c5ecad8de7cdfb877ac26a98dc 316 SUPERFAMILY SSF56199 1 311 6.15E-132 T 01-11-2018 AFULGI_00009700 2f7f72d304449a3fe12dd23ef645c77e 408 Gene3D G3DSA:2.30.30.520 4 63 5.0E-8 T 01-11-2018 IPR037222 GatD, N-terminal AFULGI_00009700 2f7f72d304449a3fe12dd23ef645c77e 408 TIGRFAM TIGR00519 asnASE_I: L-asparaginase, type I 70 404 7.1E-166 T 01-11-2018 IPR006033 L-asparaginase, type I GO:0004067|GO:0006520 Reactome: R-HSA-70614 AFULGI_00009700 2f7f72d304449a3fe12dd23ef645c77e 408 Hamap MF_00586 Glutamyl-tRNA(Gln) amidotransferase subunit D [gatD]. 10 407 47.772 T 01-11-2018 IPR011878 Glutamyl-tRNA(Gln) amidotransferase subunit D GO:0006450 AFULGI_00009700 2f7f72d304449a3fe12dd23ef645c77e 408 Gene3D G3DSA:3.40.50.40 278 408 3.7E-44 T 01-11-2018 IPR027473 L-asparaginase, C-terminal Reactome: R-HSA-70614 AFULGI_00009700 2f7f72d304449a3fe12dd23ef645c77e 408 SMART SM00870 72 391 2.4E-146 T 01-11-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 AFULGI_00009700 2f7f72d304449a3fe12dd23ef645c77e 408 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 75 83 - T 01-11-2018 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 AFULGI_00009700 2f7f72d304449a3fe12dd23ef645c77e 408 SUPERFAMILY SSF53774 65 405 2.75E-109 T 01-11-2018 IPR036152 Asparaginase/glutaminase-like superfamily Reactome: R-HSA-70614 AFULGI_00009700 2f7f72d304449a3fe12dd23ef645c77e 408 TIGRFAM TIGR02153 gatD_arch: glutamyl-tRNA(Gln) amidotransferase, subunit D 18 407 2.7E-184 T 01-11-2018 IPR011878 Glutamyl-tRNA(Gln) amidotransferase subunit D GO:0006450 AFULGI_00009700 2f7f72d304449a3fe12dd23ef645c77e 408 SUPERFAMILY SSF141300 5 54 4.71E-13 T 01-11-2018 IPR037222 GatD, N-terminal AFULGI_00009700 2f7f72d304449a3fe12dd23ef645c77e 408 Pfam PF00710 Asparaginase, N-terminal 73 262 1.8E-62 T 01-11-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 AFULGI_00009700 2f7f72d304449a3fe12dd23ef645c77e 408 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 149 159 - T 01-11-2018 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 AFULGI_00009700 2f7f72d304449a3fe12dd23ef645c77e 408 Gene3D G3DSA:3.40.50.1170 64 276 7.9E-76 T 01-11-2018 IPR037152 L-asparaginase, N-terminal domain superfamily Reactome: R-HSA-70614 AFULGI_00009700 2f7f72d304449a3fe12dd23ef645c77e 408 PRINTS PR00139 Asparaginase/glutaminase family signature 148 166 2.0E-14 T 01-11-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 AFULGI_00009700 2f7f72d304449a3fe12dd23ef645c77e 408 PRINTS PR00139 Asparaginase/glutaminase family signature 73 84 2.0E-14 T 01-11-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 AFULGI_00009700 2f7f72d304449a3fe12dd23ef645c77e 408 PRINTS PR00139 Asparaginase/glutaminase family signature 329 347 2.0E-14 T 01-11-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 AFULGI_00009700 2f7f72d304449a3fe12dd23ef645c77e 408 PIRSF PIRSF500175 4 408 3.6E-180 T 01-11-2018 IPR011878 Glutamyl-tRNA(Gln) amidotransferase subunit D GO:0006450 AFULGI_00009700 2f7f72d304449a3fe12dd23ef645c77e 408 PIRSF PIRSF001220 67 402 2.6E-102 T 01-11-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 AFULGI_00008320 14e5982bd645091d164ee7767103ccf1 168 Gene3D G3DSA:3.40.1280.10 1 168 4.4E-80 T 01-11-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal AFULGI_00008320 14e5982bd645091d164ee7767103ccf1 168 ProDom PD016584 UPF0106 MK0803 MM0086 METAL MA3241 UNCHARACTERIZED DOMAIN TA0931 APE2006 ST0333 51 166 2.0E-61 T 01-11-2018 IPR002845 tRNA ribose 2'-O-methyltransferase, aTrm56 GO:0002128|GO:0005737|GO:0008175 AFULGI_00008320 14e5982bd645091d164ee7767103ccf1 168 SUPERFAMILY SSF75217 1 166 1.83E-70 T 01-11-2018 IPR029028 Alpha/beta knot methyltransferases AFULGI_00008320 14e5982bd645091d164ee7767103ccf1 168 Pfam PF01994 tRNA ribose 2'-O-methyltransferase, aTrm56 54 166 8.9E-43 T 01-11-2018 IPR002845 tRNA ribose 2'-O-methyltransferase, aTrm56 GO:0002128|GO:0005737|GO:0008175 AFULGI_00008320 14e5982bd645091d164ee7767103ccf1 168 PIRSF PIRSF016123 1 168 9.3E-79 T 01-11-2018 IPR002845 tRNA ribose 2'-O-methyltransferase, aTrm56 GO:0002128|GO:0005737|GO:0008175 AFULGI_00008320 14e5982bd645091d164ee7767103ccf1 168 Hamap MF_00077 tRNA (cytidine(56)-2'-O)-methyltransferase. 2 168 40.496 T 01-11-2018 IPR002845 tRNA ribose 2'-O-methyltransferase, aTrm56 GO:0002128|GO:0005737|GO:0008175 AFULGI_00020480 3be09e9dec7d5b679969740b6bfcc59b 321 SMART SM00966 9 54 1.2E-7 T 01-11-2018 IPR007159 SpoVT-AbrB domain GO:0003677 AFULGI_00020480 3be09e9dec7d5b679969740b6bfcc59b 321 Gene3D G3DSA:1.20.58.220 122 233 8.2E-19 T 01-11-2018 IPR038078 PhoU-like domain superfamily AFULGI_00020480 3be09e9dec7d5b679969740b6bfcc59b 321 SUPERFAMILY SSF109755 133 319 4.92E-33 T 01-11-2018 AFULGI_00020480 3be09e9dec7d5b679969740b6bfcc59b 321 Gene3D G3DSA:1.20.58.220 234 321 2.2E-7 T 01-11-2018 IPR038078 PhoU-like domain superfamily AFULGI_00020480 3be09e9dec7d5b679969740b6bfcc59b 321 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 10 51 4.4E-9 T 01-11-2018 IPR007159 SpoVT-AbrB domain GO:0003677 AFULGI_00020480 3be09e9dec7d5b679969740b6bfcc59b 321 Pfam PF01895 PhoU domain 241 314 3.2E-6 T 01-11-2018 IPR026022 PhoU domain AFULGI_00020480 3be09e9dec7d5b679969740b6bfcc59b 321 Pfam PF01895 PhoU domain 135 225 9.3E-18 T 01-11-2018 IPR026022 PhoU domain AFULGI_00007900 4e49233cb7b43a4e5b78e0dfa9bdb299 154 Pfam PF14810 Patch-forming domain C2 of tRNA-guanine transglycosylase 8 77 2.2E-27 T 01-11-2018 IPR029402 tRNA-guanine transglycosylase, patch-forming domain C2 MetaCyc: PWY-6711|MetaCyc: PWY-7923 AFULGI_00007900 4e49233cb7b43a4e5b78e0dfa9bdb299 154 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 59 150 2.3E-13 T 01-11-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 AFULGI_00007900 4e49233cb7b43a4e5b78e0dfa9bdb299 154 Gene3D G3DSA:2.30.130.10 76 153 2.3E-32 T 01-11-2018 IPR036974 PUA domain superfamily GO:0003723 AFULGI_00007900 4e49233cb7b43a4e5b78e0dfa9bdb299 154 SUPERFAMILY SSF88697 77 152 3.7E-22 T 01-11-2018 IPR015947 PUA-like superfamily AFULGI_00007900 4e49233cb7b43a4e5b78e0dfa9bdb299 154 SUPERFAMILY SSF88802 1 76 2.42E-20 T 01-11-2018 AFULGI_00007900 4e49233cb7b43a4e5b78e0dfa9bdb299 154 Pfam PF01472 PUA domain 80 150 1.9E-19 T 01-11-2018 IPR002478 PUA domain GO:0003723 AFULGI_00007900 4e49233cb7b43a4e5b78e0dfa9bdb299 154 Gene3D G3DSA:3.10.450.90 1 75 3.7E-26 T 01-11-2018 IPR038250 TGT, patch-forming C2 domain superfamily MetaCyc: PWY-6711|MetaCyc: PWY-7923 AFULGI_00007900 4e49233cb7b43a4e5b78e0dfa9bdb299 154 SMART SM00359 79 153 2.4E-21 T 01-11-2018 IPR002478 PUA domain GO:0003723 AFULGI_00001880 d5e6f84702a824fdbaa5fbfabd5c55b6 151 SUPERFAMILY SSF50249 4 142 1.88E-34 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold AFULGI_00001880 d5e6f84702a824fdbaa5fbfabd5c55b6 151 Gene3D G3DSA:1.10.12.20 3 66 7.9E-23 T 01-11-2018 AFULGI_00001880 d5e6f84702a824fdbaa5fbfabd5c55b6 151 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 26 60 3.4E-11 T 01-11-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal AFULGI_00001880 d5e6f84702a824fdbaa5fbfabd5c55b6 151 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 63 134 1.2E-15 T 01-11-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal AFULGI_00006260 c15feaab0954d4a71c7e272c83e8d318 215 TIGRFAM TIGR01884 cas_HTH: CRISPR locus-related DNA-binding protein 44 204 4.2E-20 T 01-11-2018 IPR010163 CRISPR locus-related putative DNA-binding protein Csa3 AFULGI_00006260 c15feaab0954d4a71c7e272c83e8d318 215 SUPERFAMILY SSF52980 1 141 1.02E-5 T 01-11-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 AFULGI_00006260 c15feaab0954d4a71c7e272c83e8d318 215 Pfam PF12840 Helix-turn-helix domain 148 193 2.5E-6 T 01-11-2018 AFULGI_00006260 c15feaab0954d4a71c7e272c83e8d318 215 Gene3D G3DSA:1.10.10.10 148 207 4.4E-9 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00006260 c15feaab0954d4a71c7e272c83e8d318 215 SUPERFAMILY SSF46785 146 207 3.05E-9 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00021840 bd898ab11bd6d62980d0e38dab1eceb6 331 Pfam PF00297 Ribosomal protein L3 2 330 2.0E-97 T 01-11-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFULGI_00021840 bd898ab11bd6d62980d0e38dab1eceb6 331 Hamap MF_01325_A 50S ribosomal protein L3 [rplC]. 1 329 52.4 T 01-11-2018 IPR019928 Ribosomal protein L3, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFULGI_00021840 bd898ab11bd6d62980d0e38dab1eceb6 331 Gene3D G3DSA:3.30.1430.10 77 181 4.6E-129 T 01-11-2018 AFULGI_00021840 bd898ab11bd6d62980d0e38dab1eceb6 331 ProSitePatterns PS00474 Ribosomal protein L3 signature. 186 209 - T 01-11-2018 IPR019926 Ribosomal protein L3, conserved site AFULGI_00021840 bd898ab11bd6d62980d0e38dab1eceb6 331 Gene3D G3DSA:2.40.30.10 38 311 4.6E-129 T 01-11-2018 AFULGI_00021840 bd898ab11bd6d62980d0e38dab1eceb6 331 TIGRFAM TIGR03626 L3_arch: ribosomal protein uL3 4 328 1.4E-158 T 01-11-2018 IPR019928 Ribosomal protein L3, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFULGI_00021840 bd898ab11bd6d62980d0e38dab1eceb6 331 Gene3D G3DSA:4.10.960.10 5 250 4.6E-129 T 01-11-2018 AFULGI_00021840 bd898ab11bd6d62980d0e38dab1eceb6 331 SUPERFAMILY SSF50447 2 330 2.65E-102 T 01-11-2018 IPR009000 Translation protein, beta-barrel domain superfamily AFULGI_00006620 c45d34ba4b6fca5adf90c565e5b7fffa 528 SUPERFAMILY SSF88697 465 525 8.7E-14 T 01-11-2018 IPR015947 PUA-like superfamily AFULGI_00006620 c45d34ba4b6fca5adf90c565e5b7fffa 528 SUPERFAMILY SSF88802 394 459 1.11E-29 T 01-11-2018 AFULGI_00006620 c45d34ba4b6fca5adf90c565e5b7fffa 528 Gene3D G3DSA:2.30.130.10 460 528 3.5E-31 T 01-11-2018 IPR036974 PUA domain superfamily GO:0003723 AFULGI_00006620 c45d34ba4b6fca5adf90c565e5b7fffa 528 Gene3D G3DSA:3.20.20.105 69 222 7.3E-16 T 01-11-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 AFULGI_00006620 c45d34ba4b6fca5adf90c565e5b7fffa 528 Gene3D G3DSA:3.40.50.10630 230 394 2.8E-63 T 01-11-2018 AFULGI_00006620 c45d34ba4b6fca5adf90c565e5b7fffa 528 Pfam PF01472 PUA domain 472 524 7.1E-11 T 01-11-2018 IPR002478 PUA domain GO:0003723 AFULGI_00006620 c45d34ba4b6fca5adf90c565e5b7fffa 528 SUPERFAMILY SSF52141 245 390 7.85E-48 T 01-11-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 AFULGI_00006620 c45d34ba4b6fca5adf90c565e5b7fffa 528 SMART SM00359 460 527 6.6E-9 T 01-11-2018 IPR002478 PUA domain GO:0003723 AFULGI_00006620 c45d34ba4b6fca5adf90c565e5b7fffa 528 Pfam PF01702 Queuine tRNA-ribosyltransferase 77 197 3.2E-6 T 01-11-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 AFULGI_00006620 c45d34ba4b6fca5adf90c565e5b7fffa 528 SUPERFAMILY SSF51713 1 215 6.8E-27 T 01-11-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 AFULGI_00006620 c45d34ba4b6fca5adf90c565e5b7fffa 528 Gene3D G3DSA:3.10.450.90 395 459 2.2E-38 T 01-11-2018 IPR038250 TGT, patch-forming C2 domain superfamily MetaCyc: PWY-6711|MetaCyc: PWY-7923 AFULGI_00009620 b0f33439431e10367a107243b173cbd3 584 ProSitePatterns PS00786 5'-nucleotidase signature 2. 96 107 - T 01-11-2018 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 AFULGI_00009620 b0f33439431e10367a107243b173cbd3 584 PRINTS PR01607 Apyrase family signature 467 486 3.1E-17 T 01-11-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 AFULGI_00009620 b0f33439431e10367a107243b173cbd3 584 PRINTS PR01607 Apyrase family signature 22 40 3.1E-17 T 01-11-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 AFULGI_00009620 b0f33439431e10367a107243b173cbd3 584 PRINTS PR01607 Apyrase family signature 191 208 3.1E-17 T 01-11-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 AFULGI_00009620 b0f33439431e10367a107243b173cbd3 584 PRINTS PR01607 Apyrase family signature 210 233 3.1E-17 T 01-11-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 AFULGI_00009620 b0f33439431e10367a107243b173cbd3 584 PRINTS PR01607 Apyrase family signature 239 259 3.1E-17 T 01-11-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 AFULGI_00009620 b0f33439431e10367a107243b173cbd3 584 Pfam PF02872 5'-nucleotidase, C-terminal domain 319 483 7.5E-22 T 01-11-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 AFULGI_00009620 b0f33439431e10367a107243b173cbd3 584 Gene3D G3DSA:3.60.21.10 19 299 3.8E-75 T 01-11-2018 IPR029052 Metallo-dependent phosphatase-like AFULGI_00009620 b0f33439431e10367a107243b173cbd3 584 Pfam PF00149 Calcineurin-like phosphoesterase 25 227 1.4E-16 T 01-11-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 AFULGI_00009620 b0f33439431e10367a107243b173cbd3 584 ProSitePatterns PS00785 5'-nucleotidase signature 1. 24 36 - T 01-11-2018 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 AFULGI_00009620 b0f33439431e10367a107243b173cbd3 584 SUPERFAMILY SSF56300 20 298 2.47E-70 T 01-11-2018 AFULGI_00009620 b0f33439431e10367a107243b173cbd3 584 Gene3D G3DSA:3.90.780.10 308 486 8.2E-19 T 01-11-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 AFULGI_00009620 b0f33439431e10367a107243b173cbd3 584 SUPERFAMILY SSF55816 313 541 7.06E-19 T 01-11-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 AFULGI_00002130 0596a65e211395897748e2983bb90bf7 617 SUPERFAMILY SSF48179 141 245 7.31E-21 T 01-11-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AFULGI_00002130 0596a65e211395897748e2983bb90bf7 617 Gene3D G3DSA:3.40.50.720 1 146 2.1E-25 T 01-11-2018 AFULGI_00002130 0596a65e211395897748e2983bb90bf7 617 Pfam PF02153 Prephenate dehydrogenase 32 234 9.5E-25 T 01-11-2018 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 AFULGI_00002130 0596a65e211395897748e2983bb90bf7 617 Pfam PF01817 Chorismate mutase type II 267 342 2.2E-11 T 01-11-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 AFULGI_00002130 0596a65e211395897748e2983bb90bf7 617 SUPERFAMILY SSF55021 524 609 2.96E-19 T 01-11-2018 AFULGI_00002130 0596a65e211395897748e2983bb90bf7 617 SUPERFAMILY SSF48600 261 338 2.75E-10 T 01-11-2018 IPR036263 Chorismate mutase type II superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 AFULGI_00002130 0596a65e211395897748e2983bb90bf7 617 Pfam PF00800 Prephenate dehydratase 351 526 1.3E-55 T 01-11-2018 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 AFULGI_00002130 0596a65e211395897748e2983bb90bf7 617 SUPERFAMILY SSF53850 350 527 1.09E-50 T 01-11-2018 AFULGI_00002130 0596a65e211395897748e2983bb90bf7 617 TIGRFAM TIGR01791 CM_archaeal: chorismate mutase 263 341 1.1E-27 T 01-11-2018 IPR010950 Chorismate mutase, archaeal KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 AFULGI_00002130 0596a65e211395897748e2983bb90bf7 617 Gene3D G3DSA:3.30.70.260 527 616 1.2E-17 T 01-11-2018 AFULGI_00002130 0596a65e211395897748e2983bb90bf7 617 Pfam PF01842 ACT domain 535 593 1.3E-10 T 01-11-2018 IPR002912 ACT domain AFULGI_00002130 0596a65e211395897748e2983bb90bf7 617 Gene3D G3DSA:1.20.59.10 262 343 6.1E-9 T 01-11-2018 IPR036979 Chorismate mutase domain superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 AFULGI_00002130 0596a65e211395897748e2983bb90bf7 617 SMART SM00830 267 344 4.1E-11 T 01-11-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 AFULGI_00002130 0596a65e211395897748e2983bb90bf7 617 Gene3D G3DSA:3.40.190.10 431 513 3.8E-50 T 01-11-2018 AFULGI_00002130 0596a65e211395897748e2983bb90bf7 617 SUPERFAMILY SSF51735 2 130 4.27E-23 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily AFULGI_00002130 0596a65e211395897748e2983bb90bf7 617 Gene3D G3DSA:3.40.190.10 354 523 3.8E-50 T 01-11-2018 AFULGI_00002130 0596a65e211395897748e2983bb90bf7 617 Gene3D G3DSA:1.10.3660.10 148 261 2.0E-10 T 01-11-2018 AFULGI_00010650 78bcd082cd060ebe74c2bd0bef7af419 639 ProSitePatterns PS00455 Putative AMP-binding domain signature. 259 270 - T 01-11-2018 IPR020845 AMP-binding, conserved site AFULGI_00010650 78bcd082cd060ebe74c2bd0bef7af419 639 SUPERFAMILY SSF56801 23 634 2.35E-167 T 01-11-2018 AFULGI_00010650 78bcd082cd060ebe74c2bd0bef7af419 639 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 29 86 1.3E-12 T 01-11-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 AFULGI_00010650 78bcd082cd060ebe74c2bd0bef7af419 639 Pfam PF00501 AMP-binding enzyme 90 517 3.2E-85 T 01-11-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFULGI_00010650 78bcd082cd060ebe74c2bd0bef7af419 639 Pfam PF13193 AMP-binding enzyme C-terminal domain 526 604 9.2E-23 T 01-11-2018 IPR025110 AMP-binding enzyme, C-terminal domain AFULGI_00010650 78bcd082cd060ebe74c2bd0bef7af419 639 Gene3D G3DSA:3.40.50.12780 70 513 9.9E-97 T 01-11-2018 AFULGI_00010650 78bcd082cd060ebe74c2bd0bef7af419 639 Gene3D G3DSA:3.30.300.30 514 638 1.2E-26 T 01-11-2018 AFULGI_00015710 d9e59c1dc132fc64c2cd50b45bec1b22 741 Pfam PF12826 Helix-hairpin-helix motif 679 729 5.3E-11 T 01-11-2018 AFULGI_00015710 d9e59c1dc132fc64c2cd50b45bec1b22 741 SMART SM00487 12 211 8.7E-33 T 01-11-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFULGI_00015710 d9e59c1dc132fc64c2cd50b45bec1b22 741 Gene3D G3DSA:1.20.1320.20 216 342 3.4E-92 T 01-11-2018 AFULGI_00015710 d9e59c1dc132fc64c2cd50b45bec1b22 741 Pfam PF02732 ERCC4 domain 525 645 4.0E-27 T 01-11-2018 IPR006166 ERCC4 domain GO:0003677|GO:0004518 Reactome: R-HSA-6783310 AFULGI_00015710 d9e59c1dc132fc64c2cd50b45bec1b22 741 Gene3D G3DSA:3.40.50.300 213 481 3.4E-92 T 01-11-2018 AFULGI_00015710 d9e59c1dc132fc64c2cd50b45bec1b22 741 Gene3D G3DSA:1.10.150.20 662 733 1.3E-20 T 01-11-2018 AFULGI_00015710 d9e59c1dc132fc64c2cd50b45bec1b22 741 SUPERFAMILY SSF47781 660 729 1.11E-13 T 01-11-2018 IPR010994 RuvA domain 2-like AFULGI_00015710 d9e59c1dc132fc64c2cd50b45bec1b22 741 Pfam PF00270 DEAD/DEAH box helicase 22 175 2.6E-21 T 01-11-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 AFULGI_00015710 d9e59c1dc132fc64c2cd50b45bec1b22 741 Gene3D G3DSA:3.40.50.300 8 203 2.2E-68 T 01-11-2018 AFULGI_00015710 d9e59c1dc132fc64c2cd50b45bec1b22 741 SMART SM00891 522 603 4.7E-27 T 01-11-2018 IPR006166 ERCC4 domain GO:0003677|GO:0004518 Reactome: R-HSA-6783310 AFULGI_00015710 d9e59c1dc132fc64c2cd50b45bec1b22 741 SUPERFAMILY SSF52980 520 649 7.78E-35 T 01-11-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 AFULGI_00015710 d9e59c1dc132fc64c2cd50b45bec1b22 741 Pfam PF00271 Helicase conserved C-terminal domain 347 463 3.9E-22 T 01-11-2018 IPR001650 Helicase, C-terminal AFULGI_00015710 d9e59c1dc132fc64c2cd50b45bec1b22 741 SMART SM00490 376 464 7.3E-22 T 01-11-2018 IPR001650 Helicase, C-terminal AFULGI_00015710 d9e59c1dc132fc64c2cd50b45bec1b22 741 Gene3D G3DSA:3.40.50.10130 517 659 1.5E-48 T 01-11-2018 AFULGI_00015710 d9e59c1dc132fc64c2cd50b45bec1b22 741 SUPERFAMILY SSF52540 58 482 1.66E-54 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00011240 009c97fe696341c0fdd7490b62c83cbc 396 ProSitePatterns PS00099 Thiolases active site. 377 390 - T 01-11-2018 IPR020610 Thiolase, active site GO:0016747 AFULGI_00011240 009c97fe696341c0fdd7490b62c83cbc 396 Gene3D G3DSA:3.40.47.10 1 396 6.6E-127 T 01-11-2018 IPR016039 Thiolase-like GO:0003824 AFULGI_00011240 009c97fe696341c0fdd7490b62c83cbc 396 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 394 7.9E-122 T 01-11-2018 IPR002155 Thiolase GO:0016747 AFULGI_00011240 009c97fe696341c0fdd7490b62c83cbc 396 Pfam PF02803 Thiolase, C-terminal domain 274 395 5.3E-46 T 01-11-2018 IPR020617 Thiolase, C-terminal GO:0016747 AFULGI_00011240 009c97fe696341c0fdd7490b62c83cbc 396 ProSitePatterns PS00737 Thiolases signature 2. 342 358 - T 01-11-2018 IPR020613 Thiolase, conserved site GO:0016747 AFULGI_00011240 009c97fe696341c0fdd7490b62c83cbc 396 SUPERFAMILY SSF53901 3 273 2.88E-56 T 01-11-2018 IPR016039 Thiolase-like GO:0003824 AFULGI_00011240 009c97fe696341c0fdd7490b62c83cbc 396 SUPERFAMILY SSF53901 274 395 1.83E-44 T 01-11-2018 IPR016039 Thiolase-like GO:0003824 AFULGI_00011240 009c97fe696341c0fdd7490b62c83cbc 396 Pfam PF00108 Thiolase, N-terminal domain 4 265 1.6E-51 T 01-11-2018 IPR020616 Thiolase, N-terminal GO:0016747 AFULGI_00011240 009c97fe696341c0fdd7490b62c83cbc 396 PIRSF PIRSF000429 1 396 5.0E-121 T 01-11-2018 IPR002155 Thiolase GO:0016747 AFULGI_00020220 2df3bf4143a09c6626f7a1b5fd391274 323 Gene3D G3DSA:3.40.50.300 1 320 6.9E-96 T 01-11-2018 AFULGI_00020220 2df3bf4143a09c6626f7a1b5fd391274 323 SUPERFAMILY SSF52540 1 255 1.12E-73 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00020220 2df3bf4143a09c6626f7a1b5fd391274 323 SMART SM00382 41 242 6.1E-13 T 01-11-2018 IPR003593 AAA+ ATPase domain AFULGI_00020220 2df3bf4143a09c6626f7a1b5fd391274 323 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 234 317 6.9E-27 T 01-11-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 AFULGI_00020220 2df3bf4143a09c6626f7a1b5fd391274 323 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFULGI_00020220 2df3bf4143a09c6626f7a1b5fd391274 323 Pfam PF00005 ABC transporter 33 184 1.1E-33 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFULGI_00020220 2df3bf4143a09c6626f7a1b5fd391274 323 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 236 299 5.9E-19 T 01-11-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 AFULGI_00008360 a476a0b4ea9dbe904950fd3a4593c5f1 654 Gene3D G3DSA:1.10.1060.10 247 370 7.0E-14 T 01-11-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 AFULGI_00008360 a476a0b4ea9dbe904950fd3a4593c5f1 654 Pfam PF02665 Nitrate reductase gamma subunit 87 245 3.5E-6 T 01-11-2018 IPR023234 NarG-like domain AFULGI_00008360 a476a0b4ea9dbe904950fd3a4593c5f1 654 Pfam PF13183 4Fe-4S dicluster domain 275 350 5.0E-12 T 01-11-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFULGI_00008360 a476a0b4ea9dbe904950fd3a4593c5f1 654 Pfam PF02754 Cysteine-rich domain 418 503 1.2E-15 T 01-11-2018 IPR004017 Cysteine-rich domain AFULGI_00008360 a476a0b4ea9dbe904950fd3a4593c5f1 654 Pfam PF02754 Cysteine-rich domain 537 624 2.2E-18 T 01-11-2018 IPR004017 Cysteine-rich domain AFULGI_00008360 a476a0b4ea9dbe904950fd3a4593c5f1 654 Gene3D G3DSA:1.20.950.20 71 243 1.9E-9 T 01-11-2018 AFULGI_00008360 a476a0b4ea9dbe904950fd3a4593c5f1 654 SUPERFAMILY SSF103501 15 246 4.71E-35 T 01-11-2018 IPR036197 NarG-like superfamily AFULGI_00008360 a476a0b4ea9dbe904950fd3a4593c5f1 654 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 337 348 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFULGI_00008360 a476a0b4ea9dbe904950fd3a4593c5f1 654 SUPERFAMILY SSF46548 265 365 1.34E-19 T 01-11-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 AFULGI_00022140 16709659fef7bf3b9407629fb35a7a15 474 Hamap MF_00282 Phenylalanine--tRNA ligase alpha subunit [pheS]. 1 470 40.012 T 01-11-2018 IPR022917 Phenylalanine-tRNA ligase alpha subunit, bacterial/archaeal GO:0004826 KEGG: 00970+6.1.1.20 AFULGI_00022140 16709659fef7bf3b9407629fb35a7a15 474 Gene3D G3DSA:3.30.930.10 216 474 1.5E-91 T 01-11-2018 AFULGI_00022140 16709659fef7bf3b9407629fb35a7a15 474 SUPERFAMILY SSF46785 3 72 3.53E-7 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00022140 16709659fef7bf3b9407629fb35a7a15 474 Gene3D G3DSA:1.10.10.2310 16 198 9.8E-33 T 01-11-2018 AFULGI_00022140 16709659fef7bf3b9407629fb35a7a15 474 SUPERFAMILY SSF55681 200 470 4.33E-70 T 01-11-2018 AFULGI_00022140 16709659fef7bf3b9407629fb35a7a15 474 Pfam PF01409 tRNA synthetases class II core domain (F) 200 468 3.7E-95 T 01-11-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 AFULGI_00022140 16709659fef7bf3b9407629fb35a7a15 474 Gene3D G3DSA:1.10.10.2320 60 156 9.8E-33 T 01-11-2018 AFULGI_00022140 16709659fef7bf3b9407629fb35a7a15 474 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 149 470 1.6E-134 T 01-11-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 AFULGI_00022140 16709659fef7bf3b9407629fb35a7a15 474 Gene3D G3DSA:1.10.10.2330 73 126 9.8E-33 T 01-11-2018 AFULGI_00017680 383a7f2fd41fa22c0b6190c69d1d8709 338 SUPERFAMILY SSF47384 120 187 7.06E-5 T 01-11-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFULGI_00017680 383a7f2fd41fa22c0b6190c69d1d8709 338 SMART SM00387 224 326 3.7E-32 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFULGI_00017680 383a7f2fd41fa22c0b6190c69d1d8709 338 Gene3D G3DSA:1.10.287.130 139 190 4.1E-33 T 01-11-2018 AFULGI_00017680 383a7f2fd41fa22c0b6190c69d1d8709 338 SUPERFAMILY SSF55785 8 113 5.41E-10 T 01-11-2018 IPR035965 PAS domain superfamily AFULGI_00017680 383a7f2fd41fa22c0b6190c69d1d8709 338 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 227 325 3.5E-23 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFULGI_00017680 383a7f2fd41fa22c0b6190c69d1d8709 338 SUPERFAMILY SSF55874 220 323 2.1E-28 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFULGI_00017680 383a7f2fd41fa22c0b6190c69d1d8709 338 Gene3D G3DSA:3.30.565.10 191 323 4.1E-33 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFULGI_00017680 383a7f2fd41fa22c0b6190c69d1d8709 338 Gene3D G3DSA:3.30.450.20 2 116 1.5E-9 T 01-11-2018 AFULGI_00017680 383a7f2fd41fa22c0b6190c69d1d8709 338 SMART SM00388 132 193 5.7E-6 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFULGI_00017680 383a7f2fd41fa22c0b6190c69d1d8709 338 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 7 124 1.2E-10 T 01-11-2018 IPR000014 PAS domain AFULGI_00017680 383a7f2fd41fa22c0b6190c69d1d8709 338 PRINTS PR00344 Bacterial sensor protein C-terminal signature 288 306 3.4E-10 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFULGI_00017680 383a7f2fd41fa22c0b6190c69d1d8709 338 PRINTS PR00344 Bacterial sensor protein C-terminal signature 260 274 3.4E-10 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFULGI_00017680 383a7f2fd41fa22c0b6190c69d1d8709 338 PRINTS PR00344 Bacterial sensor protein C-terminal signature 278 288 3.4E-10 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFULGI_00010440 e476a2ac7dd8c852bf2332e8dbc95f94 280 PIRSF PIRSF006519 25 280 3.8E-94 T 01-11-2018 IPR012061 Glutamate synthase, large subunit domain 3 stand-alone protein AFULGI_00010440 e476a2ac7dd8c852bf2332e8dbc95f94 280 SUPERFAMILY SSF69336 35 278 1.02E-52 T 01-11-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 AFULGI_00010440 e476a2ac7dd8c852bf2332e8dbc95f94 280 Pfam PF01493 GXGXG motif 63 233 1.6E-35 T 01-11-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0016491|GO:0055114 AFULGI_00010440 e476a2ac7dd8c852bf2332e8dbc95f94 280 Gene3D G3DSA:2.160.20.60 48 274 4.2E-34 T 01-11-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 AFULGI_00019180 fea373c579be1ec5454b0730d7b627fc 150 SUPERFAMILY SSF54862 4 144 8.56E-28 T 01-11-2018 AFULGI_00019180 fea373c579be1ec5454b0730d7b627fc 150 TIGRFAM TIGR02060 aprB: adenylylsulfate reductase, beta subunit 1 129 5.2E-78 T 01-11-2018 IPR011802 Adenylylsulphate reductase, beta subunit AFULGI_00019180 fea373c579be1ec5454b0730d7b627fc 150 Pfam PF13187 4Fe-4S dicluster domain 9 62 6.6E-10 T 01-11-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFULGI_00019180 fea373c579be1ec5454b0730d7b627fc 150 Gene3D G3DSA:3.30.720.40 68 150 1.4E-39 T 01-11-2018 IPR038465 APS reductase, beta subunit, C-terminal domain superfamily AFULGI_00019180 fea373c579be1ec5454b0730d7b627fc 150 Gene3D G3DSA:3.30.70.20 2 67 3.4E-29 T 01-11-2018 AFULGI_00019180 fea373c579be1ec5454b0730d7b627fc 150 Pfam PF12139 Adenosine-5'-phosphosulfate reductase beta subunit 64 144 2.5E-37 T 01-11-2018 IPR022738 Adenylylsulphate reductase, beta subunit, C-terminal AFULGI_00019180 fea373c579be1ec5454b0730d7b627fc 150 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 47 58 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFULGI_00010630 f6d8c5f81c3b10ad7c3351adec986a87 436 Pfam PF02515 CoA-transferase family III 20 387 2.3E-113 T 01-11-2018 IPR003673 CoA-transferase family III GO:0003824 AFULGI_00010630 f6d8c5f81c3b10ad7c3351adec986a87 436 Gene3D G3DSA:3.30.1540.10 243 340 2.2E-102 T 01-11-2018 AFULGI_00010630 f6d8c5f81c3b10ad7c3351adec986a87 436 Gene3D G3DSA:3.40.50.10540 19 405 2.2E-102 T 01-11-2018 IPR023606 CoA-transferase family III domain superfamily AFULGI_00010630 f6d8c5f81c3b10ad7c3351adec986a87 436 SUPERFAMILY SSF89796 18 411 1.29E-109 T 01-11-2018 IPR023606 CoA-transferase family III domain superfamily AFULGI_00017090 2462cfc765decb3d553131e76e5284a2 370 Gene3D G3DSA:1.10.8.60 9 270 3.9E-64 T 01-11-2018 AFULGI_00017090 2462cfc765decb3d553131e76e5284a2 370 SUPERFAMILY SSF46785 285 365 3.81E-11 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00017090 2462cfc765decb3d553131e76e5284a2 370 Gene3D G3DSA:3.40.50.300 25 200 3.9E-64 T 01-11-2018 AFULGI_00017090 2462cfc765decb3d553131e76e5284a2 370 SUPERFAMILY SSF52540 9 273 1.83E-36 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00017090 2462cfc765decb3d553131e76e5284a2 370 TIGRFAM TIGR02928 TIGR02928: orc1/cdc6 family replication initiation protein 9 345 1.7E-71 T 01-11-2018 IPR014277 Orc1/Cdc6-type DNA replication protein, archaea AFULGI_00017090 2462cfc765decb3d553131e76e5284a2 370 SMART SM01074 294 365 6.8E-10 T 01-11-2018 IPR015163 Cdc6, C-terminal Reactome: R-HSA-176187|Reactome: R-HSA-539107|Reactome: R-HSA-68689|Reactome: R-HSA-68827|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962 AFULGI_00017090 2462cfc765decb3d553131e76e5284a2 370 Pfam PF13191 AAA ATPase domain 27 100 3.1E-8 T 01-11-2018 AFULGI_00017090 2462cfc765decb3d553131e76e5284a2 370 Hamap MF_01407 ORC1-type DNA replication protein. 2 365 22.385 T 01-11-2018 IPR014277 Orc1/Cdc6-type DNA replication protein, archaea AFULGI_00010300 77ddefc4a6bafc1137d6dba8021d704f 360 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 331 354 2.5E-45 T 01-11-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 AFULGI_00010300 77ddefc4a6bafc1137d6dba8021d704f 360 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 104 121 2.5E-45 T 01-11-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 AFULGI_00010300 77ddefc4a6bafc1137d6dba8021d704f 360 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 163 181 2.5E-45 T 01-11-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 AFULGI_00010300 77ddefc4a6bafc1137d6dba8021d704f 360 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 219 239 2.5E-45 T 01-11-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 AFULGI_00010300 77ddefc4a6bafc1137d6dba8021d704f 360 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 34 54 2.5E-45 T 01-11-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 AFULGI_00010300 77ddefc4a6bafc1137d6dba8021d704f 360 Hamap MF_00132 Type 2 DNA topoisomerase 6 subunit A [top6A]. 2 360 41.359 T 01-11-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 AFULGI_00010300 77ddefc4a6bafc1137d6dba8021d704f 360 SUPERFAMILY SSF56726 67 358 3.01E-87 T 01-11-2018 IPR036078 Spo11/DNA topoisomerase VI subunit A superfamily GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 AFULGI_00010300 77ddefc4a6bafc1137d6dba8021d704f 360 Gene3D G3DSA:3.40.1360.10 137 360 1.2E-75 T 01-11-2018 AFULGI_00010300 77ddefc4a6bafc1137d6dba8021d704f 360 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 110 127 1.1E-13 T 01-11-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 AFULGI_00010300 77ddefc4a6bafc1137d6dba8021d704f 360 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 213 234 1.1E-13 T 01-11-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 AFULGI_00010300 77ddefc4a6bafc1137d6dba8021d704f 360 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 189 206 1.1E-13 T 01-11-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 AFULGI_00010300 77ddefc4a6bafc1137d6dba8021d704f 360 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 245 261 1.1E-13 T 01-11-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 AFULGI_00010300 77ddefc4a6bafc1137d6dba8021d704f 360 Pfam PF04406 Type IIB DNA topoisomerase 69 133 2.2E-16 T 01-11-2018 IPR013049 Spo11/DNA topoisomerase VI, subunit A, N-terminal GO:0003677|GO:0003824|GO:0005524|GO:0005694|GO:0006259 Reactome: R-HSA-912446 AFULGI_00010300 77ddefc4a6bafc1137d6dba8021d704f 360 Gene3D G3DSA:1.10.10.10 1 136 1.5E-47 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00012140 63343d383543fe25d62b2a4aa295da52 189 TIGRFAM TIGR00448 rpoE: DNA-directed RNA polymerase 1 179 3.5E-91 T 01-11-2018 IPR004519 DNA-directed RNA polymerase, subunit E/RPC8 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-1834949|Reactome: R-HSA-73780|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071 AFULGI_00012140 63343d383543fe25d62b2a4aa295da52 189 Pfam PF03876 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 8 77 6.9E-19 T 01-11-2018 IPR005576 RNA polymerase Rpb7, N-terminal GO:0003899|GO:0006351 AFULGI_00012140 63343d383543fe25d62b2a4aa295da52 189 SUPERFAMILY SSF50249 83 180 9.29E-24 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold AFULGI_00012140 63343d383543fe25d62b2a4aa295da52 189 SMART SM00316 80 166 3.5E-14 T 01-11-2018 IPR022967 RNA-binding domain, S1 AFULGI_00012140 63343d383543fe25d62b2a4aa295da52 189 Gene3D G3DSA:2.40.50.140 82 188 3.6E-28 T 01-11-2018 AFULGI_00012140 63343d383543fe25d62b2a4aa295da52 189 Pfam PF00575 S1 RNA binding domain 83 147 1.1E-13 T 01-11-2018 IPR003029 S1 domain GO:0003676 AFULGI_00012140 63343d383543fe25d62b2a4aa295da52 189 SUPERFAMILY SSF88798 1 78 3.92E-22 T 01-11-2018 IPR036898 RNA polymerase Rpb7-like, N-terminal domain superfamily GO:0003899|GO:0006351 AFULGI_00012140 63343d383543fe25d62b2a4aa295da52 189 Gene3D G3DSA:3.30.1490.120 1 80 2.2E-28 T 01-11-2018 IPR036898 RNA polymerase Rpb7-like, N-terminal domain superfamily GO:0003899|GO:0006351 AFULGI_00004690 39510c3712c986004b8610eff792e840 352 SUPERFAMILY SSF54862 288 349 1.17E-11 T 01-11-2018 AFULGI_00004690 39510c3712c986004b8610eff792e840 352 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 184 195 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFULGI_00004690 39510c3712c986004b8610eff792e840 352 SUPERFAMILY SSF54862 177 308 5.87E-25 T 01-11-2018 AFULGI_00004690 39510c3712c986004b8610eff792e840 352 SUPERFAMILY SSF54862 28 222 4.81E-18 T 01-11-2018 AFULGI_00004690 39510c3712c986004b8610eff792e840 352 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 328 339 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFULGI_00004690 39510c3712c986004b8610eff792e840 352 Gene3D G3DSA:3.30.70.20 51 103 6.2E-6 T 01-11-2018 AFULGI_00004690 39510c3712c986004b8610eff792e840 352 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 75 86 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFULGI_00004690 39510c3712c986004b8610eff792e840 352 Gene3D G3DSA:3.30.70.20 107 159 3.4E-13 T 01-11-2018 AFULGI_00004690 39510c3712c986004b8610eff792e840 352 Pfam PF13237 4Fe-4S dicluster domain 292 339 1.8E-7 T 01-11-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFULGI_00004690 39510c3712c986004b8610eff792e840 352 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 112 123 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFULGI_00004690 39510c3712c986004b8610eff792e840 352 Gene3D G3DSA:3.30.70.20 210 283 6.1E-11 T 01-11-2018 AFULGI_00004690 39510c3712c986004b8610eff792e840 352 Gene3D G3DSA:3.30.70.20 1 46 6.4E-7 T 01-11-2018 AFULGI_00004690 39510c3712c986004b8610eff792e840 352 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 294 305 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFULGI_00004690 39510c3712c986004b8610eff792e840 352 Gene3D G3DSA:3.30.70.20 284 352 4.0E-11 T 01-11-2018 AFULGI_00004690 39510c3712c986004b8610eff792e840 352 Gene3D G3DSA:3.30.70.20 160 205 2.4E-5 T 01-11-2018 AFULGI_00004690 39510c3712c986004b8610eff792e840 352 Pfam PF00037 4Fe-4S binding domain 242 264 1.5E-6 T 01-11-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFULGI_00004690 39510c3712c986004b8610eff792e840 352 Pfam PF00037 4Fe-4S binding domain 177 200 4.1E-6 T 01-11-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFULGI_00004690 39510c3712c986004b8610eff792e840 352 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 248 259 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFULGI_00004690 39510c3712c986004b8610eff792e840 352 Pfam PF12800 4Fe-4S binding domain 213 229 0.11 T 01-11-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFULGI_00004690 39510c3712c986004b8610eff792e840 352 Pfam PF12838 4Fe-4S dicluster domain 112 155 1.9E-7 T 01-11-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFULGI_00004690 39510c3712c986004b8610eff792e840 352 Pfam PF12838 4Fe-4S dicluster domain 28 89 2.7E-8 T 01-11-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFULGI_00004690 39510c3712c986004b8610eff792e840 352 PIRSF PIRSF005658 268 351 5.9E-10 T 01-11-2018 AFULGI_00004690 39510c3712c986004b8610eff792e840 352 PIRSF PIRSF005658 1 276 3.1E-51 T 01-11-2018 AFULGI_00014150 1cd0a866f1644f89b6c69d8befe99582 220 Gene3D G3DSA:3.20.20.70 1 220 3.4E-78 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFULGI_00014150 1cd0a866f1644f89b6c69d8befe99582 220 SUPERFAMILY SSF51351 3 217 4.84E-45 T 01-11-2018 IPR035990 Triosephosphate isomerase superfamily GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFULGI_00014150 1cd0a866f1644f89b6c69d8befe99582 220 ProSitePatterns PS00171 Triosephosphate isomerase active site. 137 147 - T 01-11-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFULGI_00014150 1cd0a866f1644f89b6c69d8befe99582 220 Hamap MF_00147_A Triosephosphate isomerase [tpiA]. 1 220 40.607 T 01-11-2018 IPR022891 Triosephosphate isomerase, archaeal GO:0004807|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003 AFULGI_00014150 1cd0a866f1644f89b6c69d8befe99582 220 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 3 207 1.9E-86 T 01-11-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFULGI_00014150 1cd0a866f1644f89b6c69d8befe99582 220 Pfam PF00121 Triosephosphate isomerase 3 120 1.6E-11 T 01-11-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFULGI_00022350 d3ee8d914a12f28f4b61acb7e308b71f 437 SUPERFAMILY SSF69742 1 146 6.93E-37 T 01-11-2018 IPR036343 Glutamyl-tRNA reductase, N-terminal domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 AFULGI_00022350 d3ee8d914a12f28f4b61acb7e308b71f 437 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 159 293 2.7E-45 T 01-11-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase AFULGI_00022350 d3ee8d914a12f28f4b61acb7e308b71f 437 ProSitePatterns PS00747 Glutamyl-tRNA reductase signature. 87 110 - T 01-11-2018 IPR018214 Glutamyl-tRNA reductase, conserved site GO:0008883|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 AFULGI_00022350 d3ee8d914a12f28f4b61acb7e308b71f 437 Gene3D G3DSA:3.40.50.720 149 300 1.3E-48 T 01-11-2018 AFULGI_00022350 d3ee8d914a12f28f4b61acb7e308b71f 437 SUPERFAMILY SSF51735 148 301 1.11E-37 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily AFULGI_00022350 d3ee8d914a12f28f4b61acb7e308b71f 437 Gene3D G3DSA:3.30.460.30 1 148 1.0E-37 T 01-11-2018 IPR036343 Glutamyl-tRNA reductase, N-terminal domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 AFULGI_00022350 d3ee8d914a12f28f4b61acb7e308b71f 437 SUPERFAMILY SSF69075 304 409 6.28E-21 T 01-11-2018 IPR036453 Glutamyl tRNA-reductase dimerization domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 AFULGI_00022350 d3ee8d914a12f28f4b61acb7e308b71f 437 Pfam PF00745 Glutamyl-tRNAGlu reductase, dimerisation domain 307 407 6.4E-16 T 01-11-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 AFULGI_00022350 d3ee8d914a12f28f4b61acb7e308b71f 437 TIGRFAM TIGR01035 hemA: glutamyl-tRNA reductase 3 408 1.6E-159 T 01-11-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 AFULGI_00022350 d3ee8d914a12f28f4b61acb7e308b71f 437 PIRSF PIRSF000445 1 422 3.6E-131 T 01-11-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 AFULGI_00022350 d3ee8d914a12f28f4b61acb7e308b71f 437 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 6 144 7.8E-36 T 01-11-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 AFULGI_00022350 d3ee8d914a12f28f4b61acb7e308b71f 437 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 2 406 27.318 T 01-11-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 AFULGI_00019720 2bf91031c52ac07241f744dd47eda0c5 528 Pfam PF05228 CHASE4 domain 51 201 2.8E-38 T 01-11-2018 IPR007892 CHASE4 AFULGI_00019720 2bf91031c52ac07241f744dd47eda0c5 528 Gene3D G3DSA:1.10.287.130 273 390 1.3E-7 T 01-11-2018 AFULGI_00019720 2bf91031c52ac07241f744dd47eda0c5 528 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 434 522 9.0E-18 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFULGI_00019720 2bf91031c52ac07241f744dd47eda0c5 528 SMART SM00387 429 528 2.2E-22 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFULGI_00019720 2bf91031c52ac07241f744dd47eda0c5 528 Gene3D G3DSA:3.30.565.10 398 528 4.0E-25 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFULGI_00019720 2bf91031c52ac07241f744dd47eda0c5 528 SUPERFAMILY SSF55874 403 523 7.07E-24 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFULGI_00019720 2bf91031c52ac07241f744dd47eda0c5 528 SMART SM00388 334 396 7.5E-4 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFULGI_00019720 2bf91031c52ac07241f744dd47eda0c5 528 PRINTS PR00344 Bacterial sensor protein C-terminal signature 492 510 1.1E-7 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFULGI_00019720 2bf91031c52ac07241f744dd47eda0c5 528 PRINTS PR00344 Bacterial sensor protein C-terminal signature 465 479 1.1E-7 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFULGI_00001450 78d03b68e932929b9ebe7917f5f301d1 175 Pfam PF04893 Yip1 domain 20 162 7.6E-20 T 01-11-2018 IPR006977 Yip1 domain GO:0016020 AFULGI_00010290 775e41ad65eac9b14c5c7a1c523a3390 306 Pfam PF12706 Beta-lactamase superfamily domain 32 147 3.2E-12 T 01-11-2018 IPR001279 Metallo-beta-lactamase AFULGI_00010290 775e41ad65eac9b14c5c7a1c523a3390 306 Pfam PF12706 Beta-lactamase superfamily domain 199 268 5.1E-9 T 01-11-2018 IPR001279 Metallo-beta-lactamase AFULGI_00010290 775e41ad65eac9b14c5c7a1c523a3390 306 SMART SM00849 20 267 0.0079 T 01-11-2018 IPR001279 Metallo-beta-lactamase AFULGI_00010290 775e41ad65eac9b14c5c7a1c523a3390 306 TIGRFAM TIGR02651 RNase_Z: ribonuclease Z 4 301 4.3E-113 T 01-11-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 AFULGI_00010290 775e41ad65eac9b14c5c7a1c523a3390 306 SUPERFAMILY SSF56281 4 301 1.11E-80 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFULGI_00010290 775e41ad65eac9b14c5c7a1c523a3390 306 Gene3D G3DSA:3.60.15.10 3 301 2.5E-96 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFULGI_00010290 775e41ad65eac9b14c5c7a1c523a3390 306 Hamap MF_01818 Ribonuclease BN [rbn]. 3 301 38.812 T 01-11-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 AFULGI_00010710 15349b5ac276cafe8607c43fca09ed7e 361 SMART SM00382 33 227 6.2E-19 T 01-11-2018 IPR003593 AAA+ ATPase domain AFULGI_00010710 15349b5ac276cafe8607c43fca09ed7e 361 Pfam PF00005 ABC transporter 25 169 2.7E-36 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFULGI_00010710 15349b5ac276cafe8607c43fca09ed7e 361 Gene3D G3DSA:3.40.50.300 9 285 8.1E-78 T 01-11-2018 AFULGI_00010710 15349b5ac276cafe8607c43fca09ed7e 361 SUPERFAMILY SSF54631 254 357 1.24E-6 T 01-11-2018 AFULGI_00010710 15349b5ac276cafe8607c43fca09ed7e 361 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 18 290 4.3E-102 T 01-11-2018 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 AFULGI_00010710 15349b5ac276cafe8607c43fca09ed7e 361 SUPERFAMILY SSF52540 9 245 1.65E-80 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00010710 15349b5ac276cafe8607c43fca09ed7e 361 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFULGI_00012230 e340050b5e84ffbadf2d874181080218 377 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 288 352 2.6E-7 T 01-11-2018 IPR023885 4Fe4S-binding SPASM domain AFULGI_00012230 e340050b5e84ffbadf2d874181080218 377 Pfam PF04055 Radical SAM superfamily 45 212 5.1E-18 T 01-11-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFULGI_00012230 e340050b5e84ffbadf2d874181080218 377 SUPERFAMILY SSF102114 41 351 1.12E-62 T 01-11-2018 AFULGI_00012230 e340050b5e84ffbadf2d874181080218 377 PIRSF PIRSF037420 24 377 7.2E-128 T 01-11-2018 IPR017200 Coenzyme PQQ synthesis protein E AFULGI_00012230 e340050b5e84ffbadf2d874181080218 377 Pfam PF13186 Iron-sulfur cluster-binding domain 286 344 8.4E-7 T 01-11-2018 IPR023885 4Fe4S-binding SPASM domain AFULGI_00012230 e340050b5e84ffbadf2d874181080218 377 Pfam PF13353 4Fe-4S single cluster domain 42 147 6.3E-11 T 01-11-2018 AFULGI_00012230 e340050b5e84ffbadf2d874181080218 377 Gene3D G3DSA:3.20.20.70 38 350 1.4E-48 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFULGI_00018520 ecb8aa4fe1d3599eb897ec9e09311eb2 178 SUPERFAMILY SSF52317 1 176 5.64E-46 T 01-11-2018 IPR029062 Class I glutamine amidotransferase-like AFULGI_00018520 ecb8aa4fe1d3599eb897ec9e09311eb2 178 Pfam PF00117 Glutamine amidotransferase class-I 3 172 2.3E-38 T 01-11-2018 IPR017926 Glutamine amidotransferase AFULGI_00018520 ecb8aa4fe1d3599eb897ec9e09311eb2 178 PRINTS PR00097 Anthranilate synthase component II signature 90 98 8.5E-30 T 01-11-2018 AFULGI_00018520 ecb8aa4fe1d3599eb897ec9e09311eb2 178 PRINTS PR00097 Anthranilate synthase component II signature 151 164 8.5E-30 T 01-11-2018 AFULGI_00018520 ecb8aa4fe1d3599eb897ec9e09311eb2 178 PRINTS PR00097 Anthranilate synthase component II signature 44 53 8.5E-30 T 01-11-2018 AFULGI_00018520 ecb8aa4fe1d3599eb897ec9e09311eb2 178 PRINTS PR00097 Anthranilate synthase component II signature 110 122 8.5E-30 T 01-11-2018 AFULGI_00018520 ecb8aa4fe1d3599eb897ec9e09311eb2 178 PRINTS PR00097 Anthranilate synthase component II signature 2 16 8.5E-30 T 01-11-2018 AFULGI_00018520 ecb8aa4fe1d3599eb897ec9e09311eb2 178 PRINTS PR00097 Anthranilate synthase component II signature 66 77 8.5E-30 T 01-11-2018 AFULGI_00018520 ecb8aa4fe1d3599eb897ec9e09311eb2 178 PRINTS PR00096 Glutamine amidotransferase superfamily signature 44 53 6.1E-14 T 01-11-2018 AFULGI_00018520 ecb8aa4fe1d3599eb897ec9e09311eb2 178 PRINTS PR00096 Glutamine amidotransferase superfamily signature 151 164 6.1E-14 T 01-11-2018 AFULGI_00018520 ecb8aa4fe1d3599eb897ec9e09311eb2 178 PRINTS PR00096 Glutamine amidotransferase superfamily signature 66 77 6.1E-14 T 01-11-2018 AFULGI_00018520 ecb8aa4fe1d3599eb897ec9e09311eb2 178 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 1 173 1.3E-40 T 01-11-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 AFULGI_00018520 ecb8aa4fe1d3599eb897ec9e09311eb2 178 Gene3D G3DSA:3.40.50.880 1 177 1.3E-53 T 01-11-2018 IPR029062 Class I glutamine amidotransferase-like AFULGI_00018790 b55e0d398de4124973f378ae8c8b454f 341 Pfam PF01609 Transposase DDE domain 117 317 1.4E-24 T 01-11-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 AFULGI_00000750 c255039b8658e676119ad245ea9f9ee0 375 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 10 374 68.164 T 01-11-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 AFULGI_00000750 c255039b8658e676119ad245ea9f9ee0 375 PIRSF PIRSF000521 5 121 1.6E-11 T 01-11-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFULGI_00000750 c255039b8658e676119ad245ea9f9ee0 375 PIRSF PIRSF000521 114 375 1.4E-36 T 01-11-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFULGI_00000750 c255039b8658e676119ad245ea9f9ee0 375 SUPERFAMILY SSF53383 3 373 5.98E-129 T 01-11-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFULGI_00000750 c255039b8658e676119ad245ea9f9ee0 375 Pfam PF00202 Aminotransferase class-III 18 373 6.9E-117 T 01-11-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFULGI_00000750 c255039b8658e676119ad245ea9f9ee0 375 Gene3D G3DSA:3.90.1150.10 21 371 1.2E-143 T 01-11-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFULGI_00000750 c255039b8658e676119ad245ea9f9ee0 375 Gene3D G3DSA:3.40.640.10 54 293 1.2E-143 T 01-11-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFULGI_00000750 c255039b8658e676119ad245ea9f9ee0 375 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 211 248 - T 01-11-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFULGI_00000750 c255039b8658e676119ad245ea9f9ee0 375 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 11 373 9.3E-167 T 01-11-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 AFULGI_00012440 60b739586925bc598c0371f3c2be4317 476 SUPERFAMILY SSF100950 198 466 1.02E-57 T 01-11-2018 IPR037171 NagB/RpiA transferase-like AFULGI_00012440 60b739586925bc598c0371f3c2be4317 476 Gene3D G3DSA:3.30.750.70 199 308 1.6E-32 T 01-11-2018 AFULGI_00012440 60b739586925bc598c0371f3c2be4317 476 SUPERFAMILY SSF100950 3 240 3.09E-26 T 01-11-2018 IPR037171 NagB/RpiA transferase-like AFULGI_00012440 60b739586925bc598c0371f3c2be4317 476 Gene3D G3DSA:3.40.1080.20 309 460 1.2E-52 T 01-11-2018 IPR038460 Acetyl-CoA hydrolase/transferase, C-terminal domain superfamily AFULGI_00012440 60b739586925bc598c0371f3c2be4317 476 Pfam PF13336 Acetyl-CoA hydrolase/transferase C-terminal domain 291 451 1.1E-55 T 01-11-2018 IPR026888 Acetyl-CoA hydrolase/transferase C-terminal domain AFULGI_00012440 60b739586925bc598c0371f3c2be4317 476 Gene3D G3DSA:3.40.1080.10 1 190 2.0E-46 T 01-11-2018 AFULGI_00012440 60b739586925bc598c0371f3c2be4317 476 Pfam PF02550 Acetyl-CoA hydrolase/transferase N-terminal domain 3 195 6.2E-83 T 01-11-2018 IPR003702 Acetyl-CoA hydrolase/transferase GO:0003824|GO:0006084 AFULGI_00011190 f7e9b823f1703b5391ad49742689b8b2 364 Gene3D G3DSA:3.30.9.10 67 323 2.9E-62 T 01-11-2018 AFULGI_00011190 f7e9b823f1703b5391ad49742689b8b2 364 SUPERFAMILY SSF51905 2 324 4.31E-27 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFULGI_00011190 f7e9b823f1703b5391ad49742689b8b2 364 Pfam PF13450 NAD(P)-binding Rossmann-like domain 5 36 1.2E-4 T 01-11-2018 AFULGI_00011190 f7e9b823f1703b5391ad49742689b8b2 364 Gene3D G3DSA:3.50.50.60 2 307 2.9E-62 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFULGI_00011190 f7e9b823f1703b5391ad49742689b8b2 364 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 4.1E-11 T 01-11-2018 AFULGI_00011190 f7e9b823f1703b5391ad49742689b8b2 364 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 129 144 4.1E-11 T 01-11-2018 AFULGI_00011190 f7e9b823f1703b5391ad49742689b8b2 364 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 244 259 4.1E-11 T 01-11-2018 AFULGI_00011190 f7e9b823f1703b5391ad49742689b8b2 364 TIGRFAM TIGR02032 GG-red-SF: geranylgeranyl reductase family 2 273 1.4E-47 T 01-11-2018 IPR011777 Geranylgeranyl reductase family GO:0016628|GO:0055114 AFULGI_00005760 feb066743439b88dbf14aa1f3f00b0d7 154 SUPERFAMILY SSF47979 38 112 1.24E-22 T 01-11-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 AFULGI_00005760 feb066743439b88dbf14aa1f3f00b0d7 154 SMART SM00529 1 96 7.8E-21 T 01-11-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 AFULGI_00005760 feb066743439b88dbf14aa1f3f00b0d7 154 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 38 104 1.9E-24 T 01-11-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 AFULGI_00005760 feb066743439b88dbf14aa1f3f00b0d7 154 Gene3D G3DSA:1.10.10.10 5 107 1.7E-28 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00025470 b7ba3c760bc873a7cc7d787558c5bcf5 159 Gene3D G3DSA:3.40.50.300 1 159 1.3E-64 T 01-11-2018 AFULGI_00025470 b7ba3c760bc873a7cc7d787558c5bcf5 159 SUPERFAMILY SSF52540 2 116 2.31E-14 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00025470 b7ba3c760bc873a7cc7d787558c5bcf5 159 TIGRFAM TIGR00176 mobB: molybdopterin-guanine dinucleotide biosynthesis protein B 2 156 2.5E-36 T 01-11-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 AFULGI_00025470 b7ba3c760bc873a7cc7d787558c5bcf5 159 Pfam PF03205 Molybdopterin guanine dinucleotide synthesis protein B 2 133 5.4E-35 T 01-11-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 AFULGI_00022460 c115dc7ce2939279554395cefdb4c791 139 SMART SM00529 31 127 3.6E-36 T 01-11-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 AFULGI_00022460 c115dc7ce2939279554395cefdb4c791 139 Gene3D G3DSA:1.10.10.10 6 139 8.7E-26 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00022460 c115dc7ce2939279554395cefdb4c791 139 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 71 135 9.7E-13 T 01-11-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 AFULGI_00022460 c115dc7ce2939279554395cefdb4c791 139 SUPERFAMILY SSF46785 20 70 2.94E-6 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00022460 c115dc7ce2939279554395cefdb4c791 139 SUPERFAMILY SSF47979 71 135 1.96E-12 T 01-11-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 AFULGI_00022460 c115dc7ce2939279554395cefdb4c791 139 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 7 67 3.2E-22 T 01-11-2018 IPR022687 DTXR-type HTH domain GO:0003677 AFULGI_00013110 4b08fac4795ecc9b834d22cd8324e2c3 351 Pfam PF07085 DRTGG domain 210 315 6.4E-26 T 01-11-2018 IPR010766 DRTGG KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 AFULGI_00013110 4b08fac4795ecc9b834d22cd8324e2c3 351 SUPERFAMILY SSF52540 1 209 1.31E-21 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00013110 4b08fac4795ecc9b834d22cd8324e2c3 351 Pfam PF13500 AAA domain 3 203 4.4E-17 T 01-11-2018 AFULGI_00013110 4b08fac4795ecc9b834d22cd8324e2c3 351 Gene3D G3DSA:3.40.1390.20 203 337 3.6E-50 T 01-11-2018 IPR028979 HPr(Ser) kinase/phosphorylase-like, N-terminal domain superfamily AFULGI_00013110 4b08fac4795ecc9b834d22cd8324e2c3 351 SUPERFAMILY SSF75138 206 321 1.26E-30 T 01-11-2018 IPR028979 HPr(Ser) kinase/phosphorylase-like, N-terminal domain superfamily AFULGI_00013110 4b08fac4795ecc9b834d22cd8324e2c3 351 Gene3D G3DSA:3.40.50.300 2 202 2.7E-18 T 01-11-2018 AFULGI_00008800 7653194cd625f4a2952478c4d1833076 338 TIGRFAM TIGR00423 TIGR00423: radical SAM domain protein, CofH subfamily 34 337 2.7E-145 T 01-11-2018 IPR020050 FO synthase, subunit 2 GO:0016765 KEGG: 00680+2.5.1.77 AFULGI_00008800 7653194cd625f4a2952478c4d1833076 338 TIGRFAM TIGR03551 F420_cofH: 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofH subunit 11 336 4.9E-159 T 01-11-2018 IPR019940 CofH family GO:0016765 KEGG: 00680+2.5.1.77 AFULGI_00008800 7653194cd625f4a2952478c4d1833076 338 SMART SM00729 38 255 9.1E-8 T 01-11-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 AFULGI_00008800 7653194cd625f4a2952478c4d1833076 338 SUPERFAMILY SSF102114 14 329 1.2E-55 T 01-11-2018 AFULGI_00008800 7653194cd625f4a2952478c4d1833076 338 Gene3D G3DSA:3.20.20.70 3 334 3.3E-63 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFULGI_00008800 7653194cd625f4a2952478c4d1833076 338 PIRSF PIRSF004762 3 337 7.1E-119 T 01-11-2018 AFULGI_00008800 7653194cd625f4a2952478c4d1833076 338 Hamap MF_01612 FO synthase subunit 2 [cofH]. 1 338 52.392 T 01-11-2018 IPR019940 CofH family GO:0016765 KEGG: 00680+2.5.1.77 AFULGI_00008800 7653194cd625f4a2952478c4d1833076 338 Pfam PF04055 Radical SAM superfamily 42 210 4.5E-21 T 01-11-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFULGI_00011170 d4b15235d771d8a8645f2fe7a397286e 275 Gene3D G3DSA:3.40.50.300 1 232 1.2E-64 T 01-11-2018 AFULGI_00011170 d4b15235d771d8a8645f2fe7a397286e 275 ProSitePatterns PS00211 ABC transporters family signature. 122 136 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFULGI_00011170 d4b15235d771d8a8645f2fe7a397286e 275 Pfam PF00005 ABC transporter 18 149 1.3E-29 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFULGI_00011170 d4b15235d771d8a8645f2fe7a397286e 275 SMART SM00382 26 206 2.5E-11 T 01-11-2018 IPR003593 AAA+ ATPase domain AFULGI_00011170 d4b15235d771d8a8645f2fe7a397286e 275 SUPERFAMILY SSF52540 1 221 2.83E-62 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00012960 a21ec206629b82776be176a45dd0dcb4 424 Pfam PF02803 Thiolase, C-terminal domain 302 423 4.9E-49 T 01-11-2018 IPR020617 Thiolase, C-terminal GO:0016747 AFULGI_00012960 a21ec206629b82776be176a45dd0dcb4 424 SUPERFAMILY SSF53901 302 423 2.54E-45 T 01-11-2018 IPR016039 Thiolase-like GO:0003824 AFULGI_00012960 a21ec206629b82776be176a45dd0dcb4 424 ProSitePatterns PS00099 Thiolases active site. 405 418 - T 01-11-2018 IPR020610 Thiolase, active site GO:0016747 AFULGI_00012960 a21ec206629b82776be176a45dd0dcb4 424 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 113 131 - T 01-11-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0016747 AFULGI_00012960 a21ec206629b82776be176a45dd0dcb4 424 SUPERFAMILY SSF53901 76 301 4.26E-79 T 01-11-2018 IPR016039 Thiolase-like GO:0003824 AFULGI_00012960 a21ec206629b82776be176a45dd0dcb4 424 PIRSF PIRSF000429 72 424 7.4E-130 T 01-11-2018 IPR002155 Thiolase GO:0016747 AFULGI_00012960 a21ec206629b82776be176a45dd0dcb4 424 PIRSF PIRSF000429 1 50 2.0E-7 T 01-11-2018 IPR002155 Thiolase GO:0016747 AFULGI_00012960 a21ec206629b82776be176a45dd0dcb4 424 Pfam PF00108 Thiolase, N-terminal domain 3 44 2.1E-8 T 01-11-2018 IPR020616 Thiolase, N-terminal GO:0016747 AFULGI_00012960 a21ec206629b82776be176a45dd0dcb4 424 Pfam PF00108 Thiolase, N-terminal domain 76 293 2.9E-88 T 01-11-2018 IPR020616 Thiolase, N-terminal GO:0016747 AFULGI_00012960 a21ec206629b82776be176a45dd0dcb4 424 SUPERFAMILY SSF53901 2 44 3.84E-7 T 01-11-2018 IPR016039 Thiolase-like GO:0003824 AFULGI_00012960 a21ec206629b82776be176a45dd0dcb4 424 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 75 422 7.7E-141 T 01-11-2018 IPR002155 Thiolase GO:0016747 AFULGI_00015540 0f154a7f3ad25d626d1657d72f0fd3f8 612 TIGRFAM TIGR00134 gatE_arch: glutamyl-tRNA(Gln) amidotransferase, subunit E 1 610 0.0 T 01-11-2018 IPR004414 Glutamyl-tRNA(Gln) amidotransferase subunit E GO:0016884 AFULGI_00015540 0f154a7f3ad25d626d1657d72f0fd3f8 612 SMART SM00845 470 606 2.7E-17 T 01-11-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 AFULGI_00015540 0f154a7f3ad25d626d1657d72f0fd3f8 612 Gene3D G3DSA:1.10.150.380 441 531 2.8E-13 T 01-11-2018 AFULGI_00015540 0f154a7f3ad25d626d1657d72f0fd3f8 612 SUPERFAMILY SSF55261 272 395 2.29E-42 T 01-11-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 AFULGI_00015540 0f154a7f3ad25d626d1657d72f0fd3f8 612 Pfam PF02938 GAD domain 292 381 2.8E-20 T 01-11-2018 IPR029351 GAD domain Reactome: R-HSA-379726 AFULGI_00015540 0f154a7f3ad25d626d1657d72f0fd3f8 612 Pfam PF02934 GatB/GatE catalytic domain 9 436 1.4E-71 T 01-11-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 AFULGI_00015540 0f154a7f3ad25d626d1657d72f0fd3f8 612 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 175 189 - T 01-11-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 AFULGI_00015540 0f154a7f3ad25d626d1657d72f0fd3f8 612 ProDom PD609240 SUBUNIT E AMIDOTRANSFERASE 6.3.5.- LIGASE GLUTAMYL-TRNAGLN GLU-ADT BIOSYNTHESIS TRANSFERASE B 279 397 1.0E-49 T 01-11-2018 AFULGI_00015540 0f154a7f3ad25d626d1657d72f0fd3f8 612 Gene3D G3DSA:3.30.1360.30 272 395 1.3E-42 T 01-11-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 AFULGI_00015540 0f154a7f3ad25d626d1657d72f0fd3f8 612 SUPERFAMILY SSF89095 470 606 3.45E-13 T 01-11-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 AFULGI_00015540 0f154a7f3ad25d626d1657d72f0fd3f8 612 Pfam PF02637 GatB domain 471 606 3.1E-17 T 01-11-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 AFULGI_00015540 0f154a7f3ad25d626d1657d72f0fd3f8 612 SUPERFAMILY SSF55931 1 437 3.27E-101 T 01-11-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 AFULGI_00015540 0f154a7f3ad25d626d1657d72f0fd3f8 612 Hamap MF_00588 Glutamyl-tRNA(Gln) amidotransferase subunit E [gatE]. 1 612 305.137 T 01-11-2018 IPR004414 Glutamyl-tRNA(Gln) amidotransferase subunit E GO:0016884 AFULGI_00014820 7792620fb4b98840daccf5a63fd3c64b 355 Gene3D G3DSA:3.40.50.11740 52 282 2.1E-103 T 01-11-2018 AFULGI_00014820 7792620fb4b98840daccf5a63fd3c64b 355 Gene3D G3DSA:1.10.10.2140 301 351 4.0E-23 T 01-11-2018 AFULGI_00014820 7792620fb4b98840daccf5a63fd3c64b 355 Gene3D G3DSA:3.40.50.11750 8 242 2.1E-103 T 01-11-2018 AFULGI_00014820 7792620fb4b98840daccf5a63fd3c64b 355 Pfam PF01924 Hydrogenase formation hypA family 6 348 8.2E-135 T 01-11-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 AFULGI_00014820 7792620fb4b98840daccf5a63fd3c64b 355 PIRSF PIRSF005622 1 355 5.5E-144 T 01-11-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 AFULGI_00014820 7792620fb4b98840daccf5a63fd3c64b 355 TIGRFAM TIGR00075 hypD: hydrogenase expression/formation protein HypD 1 354 3.2E-169 T 01-11-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 AFULGI_00013060 7c2471faca2c1a1afafac671602747ef 281 SUPERFAMILY SSF51735 35 278 1.0E-90 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily AFULGI_00013060 7c2471faca2c1a1afafac671602747ef 281 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 164 172 1.3E-11 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFULGI_00013060 7c2471faca2c1a1afafac671602747ef 281 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 111 122 1.3E-11 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFULGI_00013060 7c2471faca2c1a1afafac671602747ef 281 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 185 204 1.3E-11 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFULGI_00013060 7c2471faca2c1a1afafac671602747ef 281 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 172 200 - T 01-11-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFULGI_00013060 7c2471faca2c1a1afafac671602747ef 281 Gene3D G3DSA:3.40.50.720 15 280 5.5E-90 T 01-11-2018 AFULGI_00013060 7c2471faca2c1a1afafac671602747ef 281 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 36 216 0.005 T 01-11-2018 AFULGI_00013060 7c2471faca2c1a1afafac671602747ef 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 206 223 1.5E-37 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFULGI_00013060 7c2471faca2c1a1afafac671602747ef 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 241 261 1.5E-37 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFULGI_00013060 7c2471faca2c1a1afafac671602747ef 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 111 122 1.5E-37 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFULGI_00013060 7c2471faca2c1a1afafac671602747ef 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 185 204 1.5E-37 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFULGI_00013060 7c2471faca2c1a1afafac671602747ef 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 37 54 1.5E-37 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFULGI_00013060 7c2471faca2c1a1afafac671602747ef 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 174 1.5E-37 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFULGI_00013060 7c2471faca2c1a1afafac671602747ef 281 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 42 278 9.6E-69 T 01-11-2018 AFULGI_00012850 e0fbcf4b7d8a1501ce33bfebcbe8d745 128 SMART SM00930 1 68 1.6E-6 T 01-11-2018 IPR018449 NIL domain AFULGI_00012850 e0fbcf4b7d8a1501ce33bfebcbe8d745 128 Pfam PF09383 NIL domain 5 65 5.1E-9 T 01-11-2018 IPR018449 NIL domain AFULGI_00012850 e0fbcf4b7d8a1501ce33bfebcbe8d745 128 Gene3D G3DSA:3.30.70.20 48 89 4.2E-5 T 01-11-2018 AFULGI_00012850 e0fbcf4b7d8a1501ce33bfebcbe8d745 128 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 109 120 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFULGI_00012850 e0fbcf4b7d8a1501ce33bfebcbe8d745 128 Gene3D G3DSA:3.30.70.20 90 127 4.1E-13 T 01-11-2018 AFULGI_00012850 e0fbcf4b7d8a1501ce33bfebcbe8d745 128 SUPERFAMILY SSF55021 3 67 5.04E-9 T 01-11-2018 AFULGI_00012850 e0fbcf4b7d8a1501ce33bfebcbe8d745 128 Pfam PF12838 4Fe-4S dicluster domain 78 123 2.6E-12 T 01-11-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFULGI_00012850 e0fbcf4b7d8a1501ce33bfebcbe8d745 128 SUPERFAMILY SSF54862 61 126 2.4E-23 T 01-11-2018 AFULGI_00012850 e0fbcf4b7d8a1501ce33bfebcbe8d745 128 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 79 90 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFULGI_00019470 8f2f1fb0f08f1af6771980fe5b21f9ec 177 Gene3D G3DSA:3.90.280.10 28 176 1.1E-48 T 01-11-2018 IPR036610 PEBP-like superfamily AFULGI_00019470 8f2f1fb0f08f1af6771980fe5b21f9ec 177 TIGRFAM TIGR00481 TIGR00481: Raf kinase inhibitor-like protein, YbhB/YbcL family 34 173 4.5E-54 T 01-11-2018 IPR005247 YbhB/YbcL AFULGI_00019470 8f2f1fb0f08f1af6771980fe5b21f9ec 177 SUPERFAMILY SSF49777 33 173 4.19E-41 T 01-11-2018 IPR036610 PEBP-like superfamily AFULGI_00019470 8f2f1fb0f08f1af6771980fe5b21f9ec 177 Pfam PF01161 Phosphatidylethanolamine-binding protein 40 173 4.2E-30 T 01-11-2018 IPR008914 Phosphatidylethanolamine-binding protein AFULGI_00005530 8d95969e3ef2e06f8129316db4ab6377 521 Gene3D G3DSA:1.10.1060.10 90 204 3.3E-9 T 01-11-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 AFULGI_00005530 8d95969e3ef2e06f8129316db4ab6377 521 SUPERFAMILY SSF46548 100 195 1.33E-14 T 01-11-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 AFULGI_00005530 8d95969e3ef2e06f8129316db4ab6377 521 Pfam PF02754 Cysteine-rich domain 384 483 1.4E-6 T 01-11-2018 IPR004017 Cysteine-rich domain AFULGI_00005530 8d95969e3ef2e06f8129316db4ab6377 521 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 169 180 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFULGI_00005530 8d95969e3ef2e06f8129316db4ab6377 521 Pfam PF13183 4Fe-4S dicluster domain 104 183 8.2E-10 T 01-11-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFULGI_00005530 8d95969e3ef2e06f8129316db4ab6377 521 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 107 118 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFULGI_00018900 5bad7b4593f6ea7f4265e68f33556ff4 170 SUPERFAMILY SSF57802 137 169 1.77E-9 T 01-11-2018 AFULGI_00018900 5bad7b4593f6ea7f4265e68f33556ff4 170 Gene3D G3DSA:1.20.1260.10 2 132 4.5E-46 T 01-11-2018 IPR012347 Ferritin-like AFULGI_00018900 5bad7b4593f6ea7f4265e68f33556ff4 170 Gene3D G3DSA:2.20.28.10 133 170 9.4E-16 T 01-11-2018 AFULGI_00018900 5bad7b4593f6ea7f4265e68f33556ff4 170 Pfam PF02915 Rubrerythrin 10 124 2.7E-28 T 01-11-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 AFULGI_00018900 5bad7b4593f6ea7f4265e68f33556ff4 170 SUPERFAMILY SSF47240 3 130 2.13E-38 T 01-11-2018 IPR009078 Ferritin-like superfamily AFULGI_00014990 ff962810827653d27c50ee4242132971 648 TIGRFAM TIGR00376 TIGR00376: putative DNA helicase 13 639 5.1E-293 T 01-11-2018 IPR004483 Helicase SMUBP-2/Hcs1-like GO:0003677|GO:0005524 AFULGI_00014990 ff962810827653d27c50ee4242132971 648 Pfam PF13087 AAA domain 416 611 3.7E-59 T 01-11-2018 AFULGI_00014990 ff962810827653d27c50ee4242132971 648 Pfam PF13086 AAA domain 169 412 8.7E-54 T 01-11-2018 AFULGI_00014990 ff962810827653d27c50ee4242132971 648 Gene3D G3DSA:3.40.50.300 439 640 6.8E-62 T 01-11-2018 AFULGI_00014990 ff962810827653d27c50ee4242132971 648 SUPERFAMILY SSF52540 162 617 1.33E-63 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00014990 ff962810827653d27c50ee4242132971 648 Gene3D G3DSA:2.40.30.270 27 121 2.1E-87 T 01-11-2018 AFULGI_00014990 ff962810827653d27c50ee4242132971 648 Gene3D G3DSA:3.40.50.300 10 424 2.1E-87 T 01-11-2018 AFULGI_00024500 b32cd589ab5716df6cbf30e0b253a5f6 237 Pfam PF02391 MoaE protein 115 213 3.4E-24 T 01-11-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 AFULGI_00024500 b32cd589ab5716df6cbf30e0b253a5f6 237 SUPERFAMILY SSF54690 118 233 1.05E-36 T 01-11-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 AFULGI_00024500 b32cd589ab5716df6cbf30e0b253a5f6 237 Gene3D G3DSA:3.90.1170.40 101 237 3.9E-36 T 01-11-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 AFULGI_00002400 b345ce1f9af7c9770640c65f3c50eac5 303 Gene3D G3DSA:3.30.300.10 189 303 4.4E-43 T 01-11-2018 AFULGI_00002400 b345ce1f9af7c9770640c65f3c50eac5 303 SUPERFAMILY SSF54810 188 303 3.4E-40 T 01-11-2018 AFULGI_00002400 b345ce1f9af7c9770640c65f3c50eac5 303 Pfam PF02540 NAD synthase 10 185 1.7E-10 T 01-11-2018 IPR022310 NAD/GMP synthase AFULGI_00002400 b345ce1f9af7c9770640c65f3c50eac5 303 Gene3D G3DSA:3.40.50.620 1 188 3.0E-72 T 01-11-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFULGI_00002400 b345ce1f9af7c9770640c65f3c50eac5 303 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 5 303 7.4E-141 T 01-11-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 AFULGI_00002400 b345ce1f9af7c9770640c65f3c50eac5 303 Pfam PF00958 GMP synthase C terminal domain 219 302 2.1E-30 T 01-11-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 AFULGI_00002400 b345ce1f9af7c9770640c65f3c50eac5 303 Hamap MF_00345 GMP synthase [glutamine-hydrolyzing] subunit B [guaAB]. 1 303 48.207 T 01-11-2018 IPR026598 GMP synthase subunit B KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 AFULGI_00002400 b345ce1f9af7c9770640c65f3c50eac5 303 SUPERFAMILY SSF52402 2 218 1.1E-52 T 01-11-2018 AFULGI_00024860 bb5fd1db68577680989cd0f2296ef82c 61 SUPERFAMILY SSF141694 1 59 5.49E-17 T 01-11-2018 AFULGI_00024860 bb5fd1db68577680989cd0f2296ef82c 61 Gene3D G3DSA:4.10.1150.10 1 61 5.7E-30 T 01-11-2018 IPR024069 AF2212-like domain superfamily AFULGI_00024860 bb5fd1db68577680989cd0f2296ef82c 61 Pfam PF01954 Protein of unknown function DUF104 1 34 2.1E-17 T 01-11-2018 IPR008203 Uncharacterised protein family UPF0165 AFULGI_00020390 e26c4452222527d399fce03d3ad8da9e 243 Gene3D G3DSA:3.40.50.1580 1 243 1.7E-65 T 01-11-2018 AFULGI_00020390 e26c4452222527d399fce03d3ad8da9e 243 Pfam PF01048 Phosphorylase superfamily 2 232 4.0E-32 T 01-11-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 AFULGI_00020390 e26c4452222527d399fce03d3ad8da9e 243 TIGRFAM TIGR01694 MTAP: methylthioadenosine phosphorylase 1 234 2.8E-88 T 01-11-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112|Reactome: R-HSA-8950505 AFULGI_00020390 e26c4452222527d399fce03d3ad8da9e 243 Hamap MF_01963 S-methyl-5'-thioadenosine phosphorylase [mtnP]. 1 243 28.22 T 01-11-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112|Reactome: R-HSA-8950505 AFULGI_00020390 e26c4452222527d399fce03d3ad8da9e 243 SUPERFAMILY SSF53167 1 238 4.32E-60 T 01-11-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 AFULGI_00010060 6a272f32e717e1e3b76a67a7fb8323cf 430 SUPERFAMILY SSF50249 3 103 1.03E-29 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold AFULGI_00010060 6a272f32e717e1e3b76a67a7fb8323cf 430 PRINTS PR01042 Aspartyl-tRNA synthetase signature 202 215 5.7E-23 T 01-11-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFULGI_00010060 6a272f32e717e1e3b76a67a7fb8323cf 430 PRINTS PR01042 Aspartyl-tRNA synthetase signature 385 399 5.7E-23 T 01-11-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFULGI_00010060 6a272f32e717e1e3b76a67a7fb8323cf 430 PRINTS PR01042 Aspartyl-tRNA synthetase signature 185 197 5.7E-23 T 01-11-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFULGI_00010060 6a272f32e717e1e3b76a67a7fb8323cf 430 PRINTS PR01042 Aspartyl-tRNA synthetase signature 345 361 5.7E-23 T 01-11-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFULGI_00010060 6a272f32e717e1e3b76a67a7fb8323cf 430 Gene3D G3DSA:3.30.930.10 105 430 4.9E-113 T 01-11-2018 AFULGI_00010060 6a272f32e717e1e3b76a67a7fb8323cf 430 Gene3D G3DSA:2.40.50.140 1 101 3.4E-30 T 01-11-2018 AFULGI_00010060 6a272f32e717e1e3b76a67a7fb8323cf 430 Pfam PF01336 OB-fold nucleic acid binding domain 17 96 3.6E-17 T 01-11-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 AFULGI_00010060 6a272f32e717e1e3b76a67a7fb8323cf 430 TIGRFAM TIGR00458 aspS_nondisc: aspartate--tRNA(Asn) ligase 3 430 2.7E-239 T 01-11-2018 IPR004523 Aspartate-tRNA synthetase, type 2 GO:0000166|GO:0004815|GO:0005524|GO:0005737|GO:0006422 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 AFULGI_00010060 6a272f32e717e1e3b76a67a7fb8323cf 430 Hamap MF_02075 Aspartate--tRNA(Asp) ligase [aspS]. 1 430 44.779 T 01-11-2018 IPR004523 Aspartate-tRNA synthetase, type 2 GO:0000166|GO:0004815|GO:0005524|GO:0005737|GO:0006422 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 AFULGI_00010060 6a272f32e717e1e3b76a67a7fb8323cf 430 Pfam PF00152 tRNA synthetases class II (D, K and N) 116 424 2.6E-94 T 01-11-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFULGI_00010060 6a272f32e717e1e3b76a67a7fb8323cf 430 SUPERFAMILY SSF55681 115 425 2.3E-100 T 01-11-2018 AFULGI_00023970 abd342d669fcf31624d4c081a93c7fcd 312 Pfam PF03466 LysR substrate binding domain 98 296 1.1E-33 T 01-11-2018 IPR005119 LysR, substrate-binding AFULGI_00023970 abd342d669fcf31624d4c081a93c7fcd 312 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 63 3.7E-16 T 01-11-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFULGI_00023970 abd342d669fcf31624d4c081a93c7fcd 312 Gene3D G3DSA:3.40.190.10 165 269 1.1E-25 T 01-11-2018 AFULGI_00023970 abd342d669fcf31624d4c081a93c7fcd 312 Gene3D G3DSA:1.10.10.10 2 88 2.1E-20 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00023970 abd342d669fcf31624d4c081a93c7fcd 312 SUPERFAMILY SSF46785 2 87 4.99E-18 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00023970 abd342d669fcf31624d4c081a93c7fcd 312 SUPERFAMILY SSF53850 98 302 8.96E-31 T 01-11-2018 AFULGI_00023970 abd342d669fcf31624d4c081a93c7fcd 312 Gene3D G3DSA:3.40.190.10 109 290 1.1E-25 T 01-11-2018 AFULGI_00019510 045e9a66c29a066f7997e2062cea9755 294 SUPERFAMILY SSF52518 2 287 7.23E-76 T 01-11-2018 IPR029061 Thiamin diphosphate-binding fold AFULGI_00019510 045e9a66c29a066f7997e2062cea9755 294 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 37 200 1.4E-27 T 01-11-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 AFULGI_00019510 045e9a66c29a066f7997e2062cea9755 294 Gene3D G3DSA:3.40.50.970 4 81 2.7E-13 T 01-11-2018 AFULGI_00019510 045e9a66c29a066f7997e2062cea9755 294 Gene3D G3DSA:3.40.50.970 82 290 2.7E-62 T 01-11-2018 AFULGI_00006170 a5ef26adb4378c695e7aca2e67c2815f 893 SUPERFAMILY SSF52540 582 889 2.91E-24 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00006170 a5ef26adb4378c695e7aca2e67c2815f 893 Gene3D G3DSA:3.40.50.300 661 891 2.9E-45 T 01-11-2018 AFULGI_00006170 a5ef26adb4378c695e7aca2e67c2815f 893 Gene3D G3DSA:3.40.50.300 1 232 1.2E-48 T 01-11-2018 AFULGI_00006170 a5ef26adb4378c695e7aca2e67c2815f 893 SUPERFAMILY SSF75712 402 497 1.7E-13 T 01-11-2018 AFULGI_00006170 a5ef26adb4378c695e7aca2e67c2815f 893 Gene3D G3DSA:1.10.287.510 399 508 1.4E-15 T 01-11-2018 AFULGI_00006170 a5ef26adb4378c695e7aca2e67c2815f 893 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 884 2.0E-14 T 01-11-2018 IPR003395 RecF/RecN/SMC, N-terminal AFULGI_00006170 a5ef26adb4378c695e7aca2e67c2815f 893 Hamap MF_00449 DNA double-strand break repair Rad50 ATPase [rad50]. 1 891 13.212 T 01-11-2018 IPR022982 DNA double-strand break repair Rad50 ATPase, archaeal type AFULGI_00006170 a5ef26adb4378c695e7aca2e67c2815f 893 SUPERFAMILY SSF52540 1 880 3.77E-34 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00006170 a5ef26adb4378c695e7aca2e67c2815f 893 Pfam PF04423 Rad50 zinc hook motif 428 473 1.1E-5 T 01-11-2018 IPR013134 RAD50, zinc hook Reactome: R-HSA-2559586|Reactome: R-HSA-5685938|Reactome: R-HSA-5685939|Reactome: R-HSA-5685942|Reactome: R-HSA-5693548|Reactome: R-HSA-5693554|Reactome: R-HSA-5693565|Reactome: R-HSA-5693568|Reactome: R-HSA-5693571|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 AFULGI_00012460 5f67b3f2fafda81b3eb26e5806360972 379 Gene3D G3DSA:3.60.70.12 5 248 9.0E-81 T 01-11-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 AFULGI_00012460 5f67b3f2fafda81b3eb26e5806360972 379 SUPERFAMILY SSF56266 11 376 8.37E-118 T 01-11-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 AFULGI_00012460 5f67b3f2fafda81b3eb26e5806360972 379 TIGRFAM TIGR00120 ArgJ: glutamate N-acetyltransferase/amino-acid acetyltransferase 1 379 3.5E-170 T 01-11-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 AFULGI_00012460 5f67b3f2fafda81b3eb26e5806360972 379 Hamap MF_01106 Arginine biosynthesis bifunctional protein ArgJ [argJ]. 1 379 115.487 T 01-11-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 AFULGI_00012460 5f67b3f2fafda81b3eb26e5806360972 379 Gene3D G3DSA:3.10.20.340 249 379 1.0E-40 T 01-11-2018 AFULGI_00012460 5f67b3f2fafda81b3eb26e5806360972 379 ProDom PD004193 ACETYLTRANSFERASE ORNITHINE ARGININE BIOSYNTHESIS ARGJ GLUTAMATE N-ACETYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIFUNCTIONAL 30 379 0.0 T 01-11-2018 AFULGI_00012460 5f67b3f2fafda81b3eb26e5806360972 379 Pfam PF01960 ArgJ family 11 379 3.0E-128 T 01-11-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 AFULGI_00017760 a60daac7dc3bda37fe9822c51c68bc06 765 SUPERFAMILY SSF55729 454 615 1.47E-9 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase AFULGI_00017760 a60daac7dc3bda37fe9822c51c68bc06 765 Pfam PF08351 Domain of unknown function (DUF1726) 80 173 9.5E-29 T 01-11-2018 IPR013562 tRNA(Met) cytidine acetyltransferase TmcA, N-terminal Reactome: R-HSA-6790901 AFULGI_00017760 a60daac7dc3bda37fe9822c51c68bc06 765 Pfam PF05127 Helicase 237 420 8.1E-56 T 01-11-2018 IPR007807 Helicase domain Reactome: R-HSA-6790901 AFULGI_00017760 a60daac7dc3bda37fe9822c51c68bc06 765 Pfam PF13718 GNAT acetyltransferase 2 460 572 1.9E-29 T 01-11-2018 IPR000182 GNAT domain AFULGI_00017760 a60daac7dc3bda37fe9822c51c68bc06 765 Pfam PF13718 GNAT acetyltransferase 2 577 624 2.3E-13 T 01-11-2018 IPR000182 GNAT domain AFULGI_00017760 a60daac7dc3bda37fe9822c51c68bc06 765 Gene3D G3DSA:3.40.50.12320 234 410 8.2E-35 T 01-11-2018 AFULGI_00017760 a60daac7dc3bda37fe9822c51c68bc06 765 Gene3D G3DSA:3.40.630.30 420 622 1.5E-58 T 01-11-2018 AFULGI_00017760 a60daac7dc3bda37fe9822c51c68bc06 765 Hamap MF_01886 tRNA(Met) cytidine acetyltransferase TmcA [tmcA]. 21 762 45.147 T 01-11-2018 IPR024914 tRNA(Met) cytidine acetyltransferase TmcA GO:0000049|GO:0002101|GO:0051391|GO:0051392 AFULGI_00017760 a60daac7dc3bda37fe9822c51c68bc06 765 SUPERFAMILY SSF52540 173 358 1.15E-8 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00017760 a60daac7dc3bda37fe9822c51c68bc06 765 Gene3D G3DSA:3.40.50.11040 7 221 2.3E-14 T 01-11-2018 AFULGI_00000430 f27375ac84e7db1b48574114716cd2d2 412 Pfam PF09861 Domain of unknown function (DUF2088) 10 201 2.3E-59 T 01-11-2018 IPR018657 LarA-like, N-terminal GO:0050043 KEGG: 00620+5.1.2.1 AFULGI_00000430 f27375ac84e7db1b48574114716cd2d2 412 Gene3D G3DSA:3.40.50.11440 38 279 8.1E-72 T 01-11-2018 AFULGI_00014750 e86558f2cf74005a295c1b4bf0ffe21d 388 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 4 24 1.2E-30 T 01-11-2018 IPR006073 GTP binding domain GO:0005525 AFULGI_00014750 e86558f2cf74005a295c1b4bf0ffe21d 388 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 25 43 1.2E-30 T 01-11-2018 IPR006073 GTP binding domain GO:0005525 AFULGI_00014750 e86558f2cf74005a295c1b4bf0ffe21d 388 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 89 107 1.2E-30 T 01-11-2018 IPR006073 GTP binding domain GO:0005525 AFULGI_00014750 e86558f2cf74005a295c1b4bf0ffe21d 388 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 72 87 1.2E-30 T 01-11-2018 IPR006073 GTP binding domain GO:0005525 AFULGI_00014750 e86558f2cf74005a295c1b4bf0ffe21d 388 Gene3D G3DSA:3.10.20.30 310 387 5.0E-33 T 01-11-2018 IPR012675 Beta-grasp domain superfamily AFULGI_00014750 e86558f2cf74005a295c1b4bf0ffe21d 388 Gene3D G3DSA:1.10.8.470 125 210 5.1E-21 T 01-11-2018 AFULGI_00014750 e86558f2cf74005a295c1b4bf0ffe21d 388 SUPERFAMILY SSF52540 2 304 6.85E-59 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00014750 e86558f2cf74005a295c1b4bf0ffe21d 388 SUPERFAMILY SSF81271 312 385 1.23E-18 T 01-11-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 AFULGI_00014750 e86558f2cf74005a295c1b4bf0ffe21d 388 Pfam PF01926 50S ribosome-binding GTPase 3 115 1.7E-20 T 01-11-2018 IPR006073 GTP binding domain GO:0005525 AFULGI_00014750 e86558f2cf74005a295c1b4bf0ffe21d 388 Pfam PF08438 GTPase of unknown function C-terminal 216 318 4.3E-36 T 01-11-2018 IPR013646 Uncharacterised GTP-binding protein, C-terminal AFULGI_00014750 e86558f2cf74005a295c1b4bf0ffe21d 388 Pfam PF02824 TGS domain 328 384 3.4E-14 T 01-11-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 AFULGI_00011370 1d0b938339e25104d7dc16fb7b1bd1c0 349 SUPERFAMILY SSF52172 1 122 1.99E-32 T 01-11-2018 IPR011006 CheY-like superfamily AFULGI_00011370 1d0b938339e25104d7dc16fb7b1bd1c0 349 Pfam PF01339 CheB methylesterase 159 338 2.1E-61 T 01-11-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 AFULGI_00011370 1d0b938339e25104d7dc16fb7b1bd1c0 349 SMART SM00448 1 115 8.5E-34 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFULGI_00011370 1d0b938339e25104d7dc16fb7b1bd1c0 349 Pfam PF00072 Response regulator receiver domain 3 104 3.3E-27 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFULGI_00011370 1d0b938339e25104d7dc16fb7b1bd1c0 349 Gene3D G3DSA:3.40.50.2300 1 135 6.4E-36 T 01-11-2018 AFULGI_00011370 1d0b938339e25104d7dc16fb7b1bd1c0 349 SUPERFAMILY SSF52738 158 342 1.83E-66 T 01-11-2018 IPR035909 Methylesterase CheB, C-terminal AFULGI_00011370 1d0b938339e25104d7dc16fb7b1bd1c0 349 PIRSF PIRSF000876 1 346 7.0E-132 T 01-11-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 AFULGI_00011370 1d0b938339e25104d7dc16fb7b1bd1c0 349 Gene3D G3DSA:3.40.50.180 151 346 2.8E-70 T 01-11-2018 IPR035909 Methylesterase CheB, C-terminal AFULGI_00011370 1d0b938339e25104d7dc16fb7b1bd1c0 349 Hamap MF_00099 Chemotaxis response regulator protein-glutamate methylesterase [cheB]. 1 343 40.699 T 01-11-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 AFULGI_00017340 e32456c05a0acb2f192d36daf20f6517 903 Pfam PF08447 PAS fold 427 498 1.3E-14 T 01-11-2018 IPR013655 PAS fold-3 GO:0005515 AFULGI_00017340 e32456c05a0acb2f192d36daf20f6517 903 SUPERFAMILY SSF55874 740 900 1.01E-37 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFULGI_00017340 e32456c05a0acb2f192d36daf20f6517 903 PRINTS PR00344 Bacterial sensor protein C-terminal signature 864 882 6.1E-13 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFULGI_00017340 e32456c05a0acb2f192d36daf20f6517 903 PRINTS PR00344 Bacterial sensor protein C-terminal signature 831 845 6.1E-13 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFULGI_00017340 e32456c05a0acb2f192d36daf20f6517 903 PRINTS PR00344 Bacterial sensor protein C-terminal signature 888 901 6.1E-13 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFULGI_00017340 e32456c05a0acb2f192d36daf20f6517 903 SUPERFAMILY SSF55785 538 661 1.73E-24 T 01-11-2018 IPR035965 PAS domain superfamily AFULGI_00017340 e32456c05a0acb2f192d36daf20f6517 903 Pfam PF13185 GAF domain 258 391 4.3E-7 T 01-11-2018 IPR003018 GAF domain GO:0005515 AFULGI_00017340 e32456c05a0acb2f192d36daf20f6517 903 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 543 670 4.9E-33 T 01-11-2018 IPR000014 PAS domain AFULGI_00017340 e32456c05a0acb2f192d36daf20f6517 903 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 401 524 9.3E-29 T 01-11-2018 IPR000014 PAS domain AFULGI_00017340 e32456c05a0acb2f192d36daf20f6517 903 SUPERFAMILY SSF55785 395 515 2.58E-26 T 01-11-2018 IPR035965 PAS domain superfamily AFULGI_00017340 e32456c05a0acb2f192d36daf20f6517 903 Gene3D G3DSA:3.30.450.20 548 675 2.5E-26 T 01-11-2018 AFULGI_00017340 e32456c05a0acb2f192d36daf20f6517 903 SUPERFAMILY SSF52172 12 116 2.64E-7 T 01-11-2018 IPR011006 CheY-like superfamily AFULGI_00017340 e32456c05a0acb2f192d36daf20f6517 903 Gene3D G3DSA:1.10.287.130 676 751 1.0E-12 T 01-11-2018 AFULGI_00017340 e32456c05a0acb2f192d36daf20f6517 903 SUPERFAMILY SSF55781 259 404 1.7E-15 T 01-11-2018 AFULGI_00017340 e32456c05a0acb2f192d36daf20f6517 903 SUPERFAMILY SSF55785 109 227 8.9E-11 T 01-11-2018 IPR035965 PAS domain superfamily AFULGI_00017340 e32456c05a0acb2f192d36daf20f6517 903 Gene3D G3DSA:3.30.450.40 244 404 1.9E-18 T 01-11-2018 IPR029016 GAF-like domain superfamily AFULGI_00017340 e32456c05a0acb2f192d36daf20f6517 903 SMART SM00086 621 663 1.4E-7 T 01-11-2018 IPR001610 PAC motif AFULGI_00017340 e32456c05a0acb2f192d36daf20f6517 903 SMART SM00086 477 517 4.6 T 01-11-2018 IPR001610 PAC motif AFULGI_00017340 e32456c05a0acb2f192d36daf20f6517 903 Pfam PF13426 PAS domain 132 228 4.8E-5 T 01-11-2018 IPR000014 PAS domain AFULGI_00017340 e32456c05a0acb2f192d36daf20f6517 903 Pfam PF13426 PAS domain 559 662 1.1E-14 T 01-11-2018 IPR000014 PAS domain AFULGI_00017340 e32456c05a0acb2f192d36daf20f6517 903 Gene3D G3DSA:3.30.450.20 410 547 6.1E-27 T 01-11-2018 AFULGI_00017340 e32456c05a0acb2f192d36daf20f6517 903 SMART SM00065 258 401 8.2E-6 T 01-11-2018 IPR003018 GAF domain GO:0005515 AFULGI_00017340 e32456c05a0acb2f192d36daf20f6517 903 Gene3D G3DSA:3.30.450.20 105 240 1.2E-15 T 01-11-2018 AFULGI_00017340 e32456c05a0acb2f192d36daf20f6517 903 Gene3D G3DSA:3.30.565.10 755 903 1.1E-37 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFULGI_00017340 e32456c05a0acb2f192d36daf20f6517 903 SMART SM00091 120 187 0.011 T 01-11-2018 IPR000014 PAS domain AFULGI_00017340 e32456c05a0acb2f192d36daf20f6517 903 SMART SM00091 405 470 4.5E-12 T 01-11-2018 IPR000014 PAS domain AFULGI_00017340 e32456c05a0acb2f192d36daf20f6517 903 SMART SM00091 547 614 1.0E-9 T 01-11-2018 IPR000014 PAS domain AFULGI_00017340 e32456c05a0acb2f192d36daf20f6517 903 SUPERFAMILY SSF47384 669 749 4.51E-16 T 01-11-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFULGI_00017340 e32456c05a0acb2f192d36daf20f6517 903 SMART SM00388 683 751 4.3E-11 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFULGI_00017340 e32456c05a0acb2f192d36daf20f6517 903 Pfam PF00512 His Kinase A (phospho-acceptor) domain 687 748 4.8E-10 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFULGI_00017340 e32456c05a0acb2f192d36daf20f6517 903 SMART SM00387 792 903 5.1E-28 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFULGI_00017340 e32456c05a0acb2f192d36daf20f6517 903 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 792 901 1.9E-21 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFULGI_00010550 0ad92593ef80e7f9f8e89bb15c6cbf4f 154 SUPERFAMILY SSF50249 9 140 5.65E-29 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold AFULGI_00010550 0ad92593ef80e7f9f8e89bb15c6cbf4f 154 Gene3D G3DSA:1.10.12.20 1 74 1.5E-22 T 01-11-2018 AFULGI_00010550 0ad92593ef80e7f9f8e89bb15c6cbf4f 154 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 72 135 1.3E-9 T 01-11-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal AFULGI_00010550 0ad92593ef80e7f9f8e89bb15c6cbf4f 154 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 39 68 4.3E-9 T 01-11-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal AFULGI_00015900 8dc0963331468e9d3ddfa68d0931b021 95 SUPERFAMILY SSF140371 6 74 6.15E-19 T 01-11-2018 IPR036519 Uncharacterised UPF0058 superfamily AFULGI_00015900 8dc0963331468e9d3ddfa68d0931b021 95 Gene3D G3DSA:1.20.1270.110 5 77 5.7E-21 T 01-11-2018 IPR036519 Uncharacterised UPF0058 superfamily AFULGI_00015900 8dc0963331468e9d3ddfa68d0931b021 95 Pfam PF01893 Uncharacterised protein family UPF0058 6 83 3.5E-18 T 01-11-2018 IPR002753 Uncharacterised protein family UPF0058 AFULGI_00006270 5fb71c87fa2c1516ba6728e9ceda3025 811 Gene3D G3DSA:1.10.3210.10 1 109 1.9E-7 T 01-11-2018 AFULGI_00006270 5fb71c87fa2c1516ba6728e9ceda3025 811 Gene3D G3DSA:3.30.70.2230 489 666 1.3E-40 T 01-11-2018 AFULGI_00006270 5fb71c87fa2c1516ba6728e9ceda3025 811 Pfam PF01966 HD domain 4 94 2.2E-7 T 01-11-2018 IPR006674 HD domain AFULGI_00006270 5fb71c87fa2c1516ba6728e9ceda3025 811 TIGRFAM TIGR02578 cas_TM1811_Csm1: CRISPR-associated protein Cas10/Csm1, subtype III-A/MTUBE 8 659 1.4E-141 T 01-11-2018 IPR013408 CRISPR-associated protein Csm1 AFULGI_00006270 5fb71c87fa2c1516ba6728e9ceda3025 811 SUPERFAMILY SSF109604 4 94 3.05E-7 T 01-11-2018 AFULGI_00003520 82c763c20d6c2832cc9922ede4fb83db 226 Pfam PF06745 KaiC 3 223 1.5E-65 T 01-11-2018 IPR014774 KaiC-like domain AFULGI_00003520 82c763c20d6c2832cc9922ede4fb83db 226 TIGRFAM TIGR03880 KaiC_arch_3: KaiC domain protein, AF_0351 family 5 226 2.9E-100 T 01-11-2018 IPR022420 Circadian clock protein, KaiC, archaea AFULGI_00003520 82c763c20d6c2832cc9922ede4fb83db 226 Gene3D G3DSA:3.40.50.300 1 225 5.5E-51 T 01-11-2018 AFULGI_00003520 82c763c20d6c2832cc9922ede4fb83db 226 SUPERFAMILY SSF52540 2 222 2.12E-40 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00005050 132a338aa2ad66ee63f9076daac1e0f9 175 Pfam PF04893 Yip1 domain 20 162 7.8E-20 T 01-11-2018 IPR006977 Yip1 domain GO:0016020 AFULGI_00009350 9f05809272b9a882f4c9099fa2352236 456 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 192 450 1.7E-95 T 01-11-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 AFULGI_00009350 9f05809272b9a882f4c9099fa2352236 456 TIGRFAM TIGR00197 yjeF_nterm: YjeF family N-terminal domain 1 189 7.5E-77 T 01-11-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 AFULGI_00009350 9f05809272b9a882f4c9099fa2352236 456 Gene3D G3DSA:3.40.1190.20 201 455 6.0E-68 T 01-11-2018 IPR029056 Ribokinase-like AFULGI_00009350 9f05809272b9a882f4c9099fa2352236 456 Pfam PF01256 Carbohydrate kinase 218 447 5.5E-47 T 01-11-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 AFULGI_00009350 9f05809272b9a882f4c9099fa2352236 456 SUPERFAMILY SSF64153 2 216 6.15E-59 T 01-11-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 AFULGI_00009350 9f05809272b9a882f4c9099fa2352236 456 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 195 455 20.796 T 01-11-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 AFULGI_00009350 9f05809272b9a882f4c9099fa2352236 456 PIRSF PIRSF017184 1 454 5.1E-101 T 01-11-2018 IPR030677 Bifunctional NAD(P)H-hydrate repair enzyme Nnr GO:0052855 MetaCyc: PWY-6938 AFULGI_00009350 9f05809272b9a882f4c9099fa2352236 456 Pfam PF03853 YjeF-related protein N-terminus 18 169 1.8E-43 T 01-11-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 AFULGI_00009350 9f05809272b9a882f4c9099fa2352236 456 SUPERFAMILY SSF53613 202 450 3.78E-56 T 01-11-2018 IPR029056 Ribokinase-like AFULGI_00009350 9f05809272b9a882f4c9099fa2352236 456 Hamap MF_01966 NAD(P)H-hydrate epimerase [nnrE]. 1 188 21.802 T 01-11-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 AFULGI_00009350 9f05809272b9a882f4c9099fa2352236 456 Gene3D G3DSA:3.40.50.10260 1 194 1.2E-60 T 01-11-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 AFULGI_00009860 5852f7ec47b18036a50b45140617e139 305 Pfam PF01974 tRNA intron endonuclease, catalytic C-terminal domain 216 294 2.4E-23 T 01-11-2018 IPR006677 tRNA intron endonuclease, catalytic domain-like GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 AFULGI_00009860 5852f7ec47b18036a50b45140617e139 305 SUPERFAMILY SSF53032 62 138 1.7E-16 T 01-11-2018 IPR036167 tRNA intron endonuclease, catalytic domain-like superfamily GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 AFULGI_00009860 5852f7ec47b18036a50b45140617e139 305 SUPERFAMILY SSF55267 3 60 3.01E-33 T 01-11-2018 IPR036740 tRNA intron endonuclease, N-terminal domain superfamily GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803 AFULGI_00009860 5852f7ec47b18036a50b45140617e139 305 SUPERFAMILY SSF55267 141 213 4.97E-18 T 01-11-2018 IPR036740 tRNA intron endonuclease, N-terminal domain superfamily GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803 AFULGI_00009860 5852f7ec47b18036a50b45140617e139 305 Gene3D G3DSA:3.40.1170.20 139 213 1.5E-24 T 01-11-2018 AFULGI_00009860 5852f7ec47b18036a50b45140617e139 305 TIGRFAM TIGR00324 endA: tRNA-intron lyase 148 301 3.7E-51 T 01-11-2018 IPR006676 tRNA-splicing endonuclease GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 AFULGI_00009860 5852f7ec47b18036a50b45140617e139 305 SUPERFAMILY SSF53032 215 295 8.72E-22 T 01-11-2018 IPR036167 tRNA intron endonuclease, catalytic domain-like superfamily GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 AFULGI_00009860 5852f7ec47b18036a50b45140617e139 305 Hamap MF_01834 tRNA-splicing endonuclease [endA]. 1 305 32.174 T 01-11-2018 IPR023516 tRNA-splicing endonuclease, archaeal long subfamily GO:0000213 MetaCyc: PWY-6689|MetaCyc: PWY-7803 AFULGI_00009860 5852f7ec47b18036a50b45140617e139 305 Pfam PF02778 tRNA intron endonuclease, N-terminal domain 151 203 1.2E-6 T 01-11-2018 IPR006678 tRNA intron endonuclease, N-terminal GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 AFULGI_00009860 5852f7ec47b18036a50b45140617e139 305 Gene3D G3DSA:3.40.1350.150 1 138 9.6E-57 T 01-11-2018 AFULGI_00009860 5852f7ec47b18036a50b45140617e139 305 Gene3D G3DSA:3.40.1350.10 214 305 6.9E-37 T 01-11-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 AFULGI_00000710 8c8f6777b48b71d468ff6401e35357e5 136 Pfam PF13187 4Fe-4S dicluster domain 56 103 7.6E-7 T 01-11-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFULGI_00000710 8c8f6777b48b71d468ff6401e35357e5 136 Gene3D G3DSA:3.30.70.20 6 117 1.5E-20 T 01-11-2018 AFULGI_00000710 8c8f6777b48b71d468ff6401e35357e5 136 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 114 125 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFULGI_00000710 8c8f6777b48b71d468ff6401e35357e5 136 Gene3D G3DSA:3.30.70.20 62 113 1.5E-20 T 01-11-2018 AFULGI_00000710 8c8f6777b48b71d468ff6401e35357e5 136 Pfam PF12800 4Fe-4S binding domain 10 23 0.3 T 01-11-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFULGI_00000710 8c8f6777b48b71d468ff6401e35357e5 136 Pfam PF00037 4Fe-4S binding domain 114 129 1.4E-4 T 01-11-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFULGI_00000710 8c8f6777b48b71d468ff6401e35357e5 136 SUPERFAMILY SSF54862 3 132 5.13E-31 T 01-11-2018 AFULGI_00022620 475981803c33718d11f3ed4920d3a8b7 354 Pfam PF13183 4Fe-4S dicluster domain 4 61 9.3E-8 T 01-11-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFULGI_00022620 475981803c33718d11f3ed4920d3a8b7 354 SUPERFAMILY SSF46548 4 81 5.23E-14 T 01-11-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 AFULGI_00022620 475981803c33718d11f3ed4920d3a8b7 354 Pfam PF02754 Cysteine-rich domain 240 325 6.1E-18 T 01-11-2018 IPR004017 Cysteine-rich domain AFULGI_00022620 475981803c33718d11f3ed4920d3a8b7 354 Pfam PF02754 Cysteine-rich domain 123 207 6.5E-17 T 01-11-2018 IPR004017 Cysteine-rich domain AFULGI_00022620 475981803c33718d11f3ed4920d3a8b7 354 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 47 58 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFULGI_00022620 475981803c33718d11f3ed4920d3a8b7 354 Gene3D G3DSA:1.10.1060.10 1 76 3.7E-6 T 01-11-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 AFULGI_00007860 6c09d5163c2af3d27bd62800d20bd0b5 273 Gene3D G3DSA:3.30.300.110 1 80 6.0E-22 T 01-11-2018 AFULGI_00007860 6c09d5163c2af3d27bd62800d20bd0b5 273 Pfam PF02475 Met-10+ like-protein 22 221 1.0E-72 T 01-11-2018 IPR030382 SAM-dependent methyltransferase TRM5/TYW2-type Reactome: R-HSA-6782861 AFULGI_00007860 6c09d5163c2af3d27bd62800d20bd0b5 273 SUPERFAMILY SSF53335 13 272 1.92E-63 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFULGI_00007860 6c09d5163c2af3d27bd62800d20bd0b5 273 Gene3D G3DSA:3.40.50.150 82 273 7.6E-49 T 01-11-2018 AFULGI_00000510 f43c504000d788d9baf050ee50906495 174 Pfam PF03657 Uncharacterised protein family (UPF0113) 1 167 4.0E-73 T 01-11-2018 IPR005155 Ribosome biogenesis factor NIP7-like Reactome: R-HSA-6791226 AFULGI_00000510 f43c504000d788d9baf050ee50906495 174 Gene3D G3DSA:2.30.130.10 87 167 8.9E-25 T 01-11-2018 IPR036974 PUA domain superfamily GO:0003723 AFULGI_00000510 f43c504000d788d9baf050ee50906495 174 SMART SM00359 88 166 3.1E-15 T 01-11-2018 IPR002478 PUA domain GO:0003723 AFULGI_00000510 f43c504000d788d9baf050ee50906495 174 SUPERFAMILY SSF88697 88 162 1.74E-11 T 01-11-2018 IPR015947 PUA-like superfamily AFULGI_00019780 b6565f8bdc9ec530a0181a992e4c8d0c 440 Pfam PF03949 Malic enzyme, NAD binding domain 168 396 3.1E-25 T 01-11-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 AFULGI_00019780 b6565f8bdc9ec530a0181a992e4c8d0c 440 SMART SM00919 167 397 9.3E-113 T 01-11-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 AFULGI_00019780 b6565f8bdc9ec530a0181a992e4c8d0c 440 Gene3D G3DSA:3.40.50.720 165 440 1.4E-94 T 01-11-2018 AFULGI_00019780 b6565f8bdc9ec530a0181a992e4c8d0c 440 SUPERFAMILY SSF53223 17 165 1.37E-54 T 01-11-2018 AFULGI_00019780 b6565f8bdc9ec530a0181a992e4c8d0c 440 Pfam PF00390 Malic enzyme, N-terminal domain 23 155 2.0E-28 T 01-11-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 AFULGI_00019780 b6565f8bdc9ec530a0181a992e4c8d0c 440 SUPERFAMILY SSF51735 167 428 2.66E-73 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily AFULGI_00019780 b6565f8bdc9ec530a0181a992e4c8d0c 440 Gene3D G3DSA:3.40.50.10380 2 164 3.8E-71 T 01-11-2018 IPR037062 Malic enzyme, N-terminal domain superfamily GO:0004471|GO:0055114 AFULGI_00019780 b6565f8bdc9ec530a0181a992e4c8d0c 440 PIRSF PIRSF000106 33 120 6.9E-11 T 01-11-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 AFULGI_00019780 b6565f8bdc9ec530a0181a992e4c8d0c 440 PIRSF PIRSF000106 116 428 1.3E-71 T 01-11-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 AFULGI_00019780 b6565f8bdc9ec530a0181a992e4c8d0c 440 SMART SM01274 22 155 1.7E-79 T 01-11-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 AFULGI_00009760 3c328eb048218864f66818fca321e947 501 Gene3D G3DSA:3.40.50.300 1 238 1.3E-57 T 01-11-2018 AFULGI_00009760 3c328eb048218864f66818fca321e947 501 SUPERFAMILY SSF52540 256 480 1.98E-44 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00009760 3c328eb048218864f66818fca321e947 501 Pfam PF00005 ABC transporter 274 425 8.1E-18 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFULGI_00009760 3c328eb048218864f66818fca321e947 501 Gene3D G3DSA:3.40.50.300 254 488 6.5E-44 T 01-11-2018 AFULGI_00009760 3c328eb048218864f66818fca321e947 501 SMART SM00382 29 217 1.8E-12 T 01-11-2018 IPR003593 AAA+ ATPase domain AFULGI_00009760 3c328eb048218864f66818fca321e947 501 SUPERFAMILY SSF52540 3 221 1.39E-60 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00009760 3c328eb048218864f66818fca321e947 501 ProSitePatterns PS00211 ABC transporters family signature. 398 412 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFULGI_00009760 3c328eb048218864f66818fca321e947 501 Pfam PF00005 ABC transporter 21 169 9.5E-33 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFULGI_00004390 496d691d977797325d9d353d1cc820f9 256 Gene3D G3DSA:3.90.226.10 2 198 4.1E-73 T 01-11-2018 AFULGI_00004390 496d691d977797325d9d353d1cc820f9 256 SUPERFAMILY SSF52096 2 256 1.24E-91 T 01-11-2018 IPR029045 ClpP/crotonase-like domain superfamily AFULGI_00004390 496d691d977797325d9d353d1cc820f9 256 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 255 8.6E-76 T 01-11-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 AFULGI_00004390 496d691d977797325d9d353d1cc820f9 256 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 97 117 - T 01-11-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 AFULGI_00004390 496d691d977797325d9d353d1cc820f9 256 Gene3D G3DSA:1.10.12.10 199 256 3.2E-26 T 01-11-2018 IPR014748 Enoyl-CoA hydratase, C-terminal AFULGI_00015810 935db996f37ca59d097947d527d30d7e 131 Gene3D G3DSA:3.40.50.1010 1 131 2.1E-33 T 01-11-2018 AFULGI_00015810 935db996f37ca59d097947d527d30d7e 131 Pfam PF01850 PIN domain 2 124 7.7E-14 T 01-11-2018 IPR002716 PIN domain AFULGI_00015810 935db996f37ca59d097947d527d30d7e 131 SUPERFAMILY SSF88723 1 131 3.08E-29 T 01-11-2018 IPR029060 PIN-like domain superfamily AFULGI_00015810 935db996f37ca59d097947d527d30d7e 131 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 2 130 10.637 T 01-11-2018 IPR022907 VapC family GO:0004540 AFULGI_00017360 d6613fcdfe628924ee03468c55e7237f 403 Hamap MF_00168 Queuine tRNA-ribosyltransferase [tgt]. 3 403 51.754 T 01-11-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 AFULGI_00017360 d6613fcdfe628924ee03468c55e7237f 403 SUPERFAMILY SSF51713 2 401 2.09E-131 T 01-11-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 AFULGI_00017360 d6613fcdfe628924ee03468c55e7237f 403 TIGRFAM TIGR00430 Q_tRNA_tgt: tRNA-guanine transglycosylase 5 402 2.2E-177 T 01-11-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 AFULGI_00017360 d6613fcdfe628924ee03468c55e7237f 403 Pfam PF01702 Queuine tRNA-ribosyltransferase 160 400 4.1E-83 T 01-11-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 AFULGI_00017360 d6613fcdfe628924ee03468c55e7237f 403 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 5 399 2.1E-169 T 01-11-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 AFULGI_00014920 bda16bb296e25ce76abd59b92ba55803 566 Gene3D G3DSA:1.10.645.10 528 566 1.5E-5 T 01-11-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFULGI_00014920 bda16bb296e25ce76abd59b92ba55803 566 Gene3D G3DSA:1.10.645.10 1 498 1.6E-136 T 01-11-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFULGI_00014920 bda16bb296e25ce76abd59b92ba55803 566 Pfam PF00374 Nickel-dependent hydrogenase 46 118 7.2E-27 T 01-11-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 AFULGI_00014920 bda16bb296e25ce76abd59b92ba55803 566 Pfam PF00374 Nickel-dependent hydrogenase 149 492 1.2E-67 T 01-11-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 AFULGI_00014920 bda16bb296e25ce76abd59b92ba55803 566 SUPERFAMILY SSF56762 3 490 1.23E-113 T 01-11-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFULGI_00014920 bda16bb296e25ce76abd59b92ba55803 566 ProSitePatterns PS00508 Nickel-dependent hydrogenases large subunit signature 2. 554 563 - T 01-11-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 AFULGI_00005250 db73466c18a8430b751a413f234d01a8 294 SUPERFAMILY SSF52833 83 166 2.48E-15 T 01-11-2018 IPR036249 Thioredoxin-like superfamily AFULGI_00005250 db73466c18a8430b751a413f234d01a8 294 Gene3D G3DSA:3.40.30.80 3 156 1.6E-15 T 01-11-2018 AFULGI_00005250 db73466c18a8430b751a413f234d01a8 294 Pfam PF13192 Thioredoxin domain 95 163 1.5E-11 T 01-11-2018 IPR012336 Thioredoxin-like fold AFULGI_00005250 db73466c18a8430b751a413f234d01a8 294 SUPERFAMILY SSF48371 193 274 1.9E-6 T 01-11-2018 IPR016024 Armadillo-type fold AFULGI_00005250 db73466c18a8430b751a413f234d01a8 294 Gene3D G3DSA:1.25.10.10 157 293 9.7E-7 T 01-11-2018 IPR011989 Armadillo-like helical AFULGI_00022840 eb89ae93d17cc8ea46f3e843dd941943 379 Gene3D G3DSA:3.40.50.1970 2 172 2.6E-42 T 01-11-2018 AFULGI_00022840 eb89ae93d17cc8ea46f3e843dd941943 379 SUPERFAMILY SSF56796 8 372 1.44E-102 T 01-11-2018 AFULGI_00022840 eb89ae93d17cc8ea46f3e843dd941943 379 Gene3D G3DSA:1.20.1090.10 173 370 1.7E-61 T 01-11-2018 AFULGI_00022840 eb89ae93d17cc8ea46f3e843dd941943 379 Pfam PF00465 Iron-containing alcohol dehydrogenase 10 362 5.8E-103 T 01-11-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 AFULGI_00022840 eb89ae93d17cc8ea46f3e843dd941943 379 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 161 189 - T 01-11-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 AFULGI_00012010 f8adbf5f9072fbd2f416eca8f92cb77a 288 PIRSF PIRSF006593 1 288 3.5E-100 T 01-11-2018 IPR014444 Uncharacterised conserved protein UCP006593 AFULGI_00012010 f8adbf5f9072fbd2f416eca8f92cb77a 288 Gene3D G3DSA:1.10.285.20 69 139 2.3E-29 T 01-11-2018 AFULGI_00012010 f8adbf5f9072fbd2f416eca8f92cb77a 288 SUPERFAMILY SSF111321 7 285 1.44E-83 T 01-11-2018 IPR036075 AF1104-like superfamily AFULGI_00012010 f8adbf5f9072fbd2f416eca8f92cb77a 288 Gene3D G3DSA:1.10.8.380 7 68 6.2E-33 T 01-11-2018 AFULGI_00012010 f8adbf5f9072fbd2f416eca8f92cb77a 288 Pfam PF01937 Protein of unknown function DUF89 6 282 2.1E-57 T 01-11-2018 IPR002791 Domain of unknown function DUF89 AFULGI_00012010 f8adbf5f9072fbd2f416eca8f92cb77a 288 Gene3D G3DSA:3.40.50.10880 140 288 2.5E-57 T 01-11-2018 AFULGI_00006580 3dc2cb17fdea4fc368ac100b3897f49d 625 Pfam PF10060 Uncharacterized membrane protein (DUF2298) 57 437 2.1E-63 T 01-11-2018 IPR018746 Protein of unknown function DUF2298 AFULGI_00006580 3dc2cb17fdea4fc368ac100b3897f49d 625 TIGRFAM TIGR03662 Chlor_Arch_YYY: chlor_Arch_YYY domain 14 621 6.7E-96 T 01-11-2018 IPR018746 Protein of unknown function DUF2298 AFULGI_00008090 f824e029a33562827e11d66f593b3f25 87 TIGRFAM TIGR01165 cbiN: cobalt transport protein 4 80 5.5E-39 T 01-11-2018 IPR003705 Cobalt transport protein CbiN GO:0006824|GO:0009236|GO:0015087|GO:0016020 AFULGI_00008090 f824e029a33562827e11d66f593b3f25 87 Pfam PF02553 Cobalt transport protein component CbiN 4 65 7.9E-27 T 01-11-2018 IPR003705 Cobalt transport protein CbiN GO:0006824|GO:0009236|GO:0015087|GO:0016020 AFULGI_00008090 f824e029a33562827e11d66f593b3f25 87 Hamap MF_00330 Cobalt transport protein CbiN [cbiN]. 1 87 38.407 T 01-11-2018 IPR003705 Cobalt transport protein CbiN GO:0006824|GO:0009236|GO:0015087|GO:0016020 AFULGI_00003060 a73ce0f2a8d9a0ba909c4665516ef575 68 Pfam PF01954 Protein of unknown function DUF104 6 57 6.0E-20 T 01-11-2018 IPR008203 Uncharacterised protein family UPF0165 AFULGI_00003060 a73ce0f2a8d9a0ba909c4665516ef575 68 SUPERFAMILY SSF141694 6 50 2.3E-15 T 01-11-2018 AFULGI_00003060 a73ce0f2a8d9a0ba909c4665516ef575 68 Gene3D G3DSA:4.10.1150.10 6 65 4.5E-18 T 01-11-2018 IPR024069 AF2212-like domain superfamily AFULGI_00011310 df00d4d8bd6ca73a25e7bdac652ff029 388 SUPERFAMILY SSF55785 105 205 2.97E-8 T 01-11-2018 IPR035965 PAS domain superfamily AFULGI_00011310 df00d4d8bd6ca73a25e7bdac652ff029 388 SMART SM00388 310 368 3.1E-7 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFULGI_00011310 df00d4d8bd6ca73a25e7bdac652ff029 388 SMART SM00091 102 165 0.021 T 01-11-2018 IPR000014 PAS domain AFULGI_00011310 df00d4d8bd6ca73a25e7bdac652ff029 388 SMART SM00091 6 68 6.9 T 01-11-2018 IPR000014 PAS domain AFULGI_00011310 df00d4d8bd6ca73a25e7bdac652ff029 388 Pfam PF00512 His Kinase A (phospho-acceptor) domain 312 365 4.0E-7 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFULGI_00011310 df00d4d8bd6ca73a25e7bdac652ff029 388 Gene3D G3DSA:3.30.450.20 98 217 4.1E-9 T 01-11-2018 AFULGI_00011310 df00d4d8bd6ca73a25e7bdac652ff029 388 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 101 210 8.3E-10 T 01-11-2018 IPR000014 PAS domain AFULGI_00011310 df00d4d8bd6ca73a25e7bdac652ff029 388 Gene3D G3DSA:1.10.287.130 260 361 3.8E-5 T 01-11-2018 AFULGI_00011310 df00d4d8bd6ca73a25e7bdac652ff029 388 Pfam PF08448 PAS fold 108 208 2.4E-13 T 01-11-2018 IPR013656 PAS fold-4 AFULGI_00011310 df00d4d8bd6ca73a25e7bdac652ff029 388 Pfam PF13188 PAS domain 8 51 1.0E-4 T 01-11-2018 IPR000014 PAS domain AFULGI_00019940 dacd02bed487647921e9624a87e29155 191 Gene3D G3DSA:1.10.10.10 1 57 3.2E-15 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00019940 dacd02bed487647921e9624a87e29155 191 ProSitePatterns PS00519 AsnC-type HTH domain signature. 25 51 - T 01-11-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site AFULGI_00019940 dacd02bed487647921e9624a87e29155 191 Pfam PF13412 Winged helix-turn-helix DNA-binding 8 53 3.3E-15 T 01-11-2018 AFULGI_00019940 dacd02bed487647921e9624a87e29155 191 SMART SM00344 7 109 6.2E-27 T 01-11-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 AFULGI_00019940 dacd02bed487647921e9624a87e29155 191 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 7 23 2.5E-12 T 01-11-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFULGI_00019940 dacd02bed487647921e9624a87e29155 191 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 34 53 2.5E-12 T 01-11-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFULGI_00019940 dacd02bed487647921e9624a87e29155 191 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 23 34 2.5E-12 T 01-11-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFULGI_00019940 dacd02bed487647921e9624a87e29155 191 SUPERFAMILY SSF46785 2 73 1.6E-13 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00007020 90898d8f1e42ad22597ea12ed0088b53 433 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 2 432 35.522 T 01-11-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 AFULGI_00007020 90898d8f1e42ad22597ea12ed0088b53 433 Pfam PF00448 SRP54-type protein, GTPase domain 95 286 2.0E-75 T 01-11-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 AFULGI_00007020 90898d8f1e42ad22597ea12ed0088b53 433 Pfam PF02978 Signal peptide binding domain 315 415 1.8E-29 T 01-11-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 AFULGI_00007020 90898d8f1e42ad22597ea12ed0088b53 433 SUPERFAMILY SSF47446 288 419 3.14E-37 T 01-11-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 AFULGI_00007020 90898d8f1e42ad22597ea12ed0088b53 433 SUPERFAMILY SSF47364 4 85 2.09E-19 T 01-11-2018 IPR036225 SRP/SRP receptor, N-terminal Reactome: R-HSA-1799339 AFULGI_00007020 90898d8f1e42ad22597ea12ed0088b53 433 SMART SM00962 93 286 1.3E-99 T 01-11-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 AFULGI_00007020 90898d8f1e42ad22597ea12ed0088b53 433 SUPERFAMILY SSF52540 94 288 1.45E-49 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00007020 90898d8f1e42ad22597ea12ed0088b53 433 Gene3D G3DSA:1.10.260.30 308 425 2.1E-44 T 01-11-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 AFULGI_00007020 90898d8f1e42ad22597ea12ed0088b53 433 Gene3D G3DSA:1.20.120.140 5 296 5.0E-109 T 01-11-2018 AFULGI_00007020 90898d8f1e42ad22597ea12ed0088b53 433 Pfam PF02881 SRP54-type protein, helical bundle domain 4 79 2.1E-17 T 01-11-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 AFULGI_00007020 90898d8f1e42ad22597ea12ed0088b53 433 SMART SM00382 92 276 4.0E-10 T 01-11-2018 IPR003593 AAA+ ATPase domain AFULGI_00007020 90898d8f1e42ad22597ea12ed0088b53 433 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 259 272 - T 01-11-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 AFULGI_00007020 90898d8f1e42ad22597ea12ed0088b53 433 Gene3D G3DSA:3.40.50.300 86 275 5.0E-109 T 01-11-2018 AFULGI_00007020 90898d8f1e42ad22597ea12ed0088b53 433 SMART SM00963 2 83 1.4E-14 T 01-11-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 AFULGI_00004340 1f2c9fbb94f35bdb3cefc1cb9e8dab99 248 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFULGI_00004340 1f2c9fbb94f35bdb3cefc1cb9e8dab99 248 Pfam PF00005 ABC transporter 18 162 2.7E-30 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFULGI_00004340 1f2c9fbb94f35bdb3cefc1cb9e8dab99 248 SUPERFAMILY SSF52540 2 222 4.62E-60 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00004340 1f2c9fbb94f35bdb3cefc1cb9e8dab99 248 SMART SM00382 26 211 9.0E-19 T 01-11-2018 IPR003593 AAA+ ATPase domain AFULGI_00004340 1f2c9fbb94f35bdb3cefc1cb9e8dab99 248 Gene3D G3DSA:3.40.50.300 1 245 2.9E-68 T 01-11-2018 AFULGI_00026480 a531105b70765e384ecda249365979eb 188 PIRSF PIRSF037663 1 75 0.18 T 01-11-2018 IPR017255 Acetyltransferase, GNAT, predicted AFULGI_00026480 a531105b70765e384ecda249365979eb 188 PIRSF PIRSF037663 85 175 3.5E-9 T 01-11-2018 IPR017255 Acetyltransferase, GNAT, predicted AFULGI_00026480 a531105b70765e384ecda249365979eb 188 Pfam PF00583 Acetyltransferase (GNAT) family 12 161 5.6E-29 T 01-11-2018 IPR000182 GNAT domain AFULGI_00026480 a531105b70765e384ecda249365979eb 188 SUPERFAMILY SSF55729 3 186 3.49E-19 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase AFULGI_00026480 a531105b70765e384ecda249365979eb 188 Gene3D G3DSA:3.40.630.30 2 186 3.9E-19 T 01-11-2018 AFULGI_00005580 107257c5e188dd29dcb1ea25714d3bee 619 PRINTS PR01047 Threonyl-tRNA synthetase signature 283 311 1.7E-31 T 01-11-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 AFULGI_00005580 107257c5e188dd29dcb1ea25714d3bee 619 PRINTS PR01047 Threonyl-tRNA synthetase signature 317 340 1.7E-31 T 01-11-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 AFULGI_00005580 107257c5e188dd29dcb1ea25714d3bee 619 PRINTS PR01047 Threonyl-tRNA synthetase signature 460 473 1.7E-31 T 01-11-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 AFULGI_00005580 107257c5e188dd29dcb1ea25714d3bee 619 PRINTS PR01047 Threonyl-tRNA synthetase signature 495 507 1.7E-31 T 01-11-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 AFULGI_00005580 107257c5e188dd29dcb1ea25714d3bee 619 PRINTS PR01047 Threonyl-tRNA synthetase signature 417 445 1.7E-31 T 01-11-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 AFULGI_00005580 107257c5e188dd29dcb1ea25714d3bee 619 SUPERFAMILY SSF52954 493 600 5.44E-27 T 01-11-2018 AFULGI_00005580 107257c5e188dd29dcb1ea25714d3bee 619 Pfam PF08915 Archaea-specific editing domain of threonyl-tRNA synthetase 1 131 2.6E-50 T 01-11-2018 IPR015011 Threonyl-tRNA synthetase, editing domain, archaea GO:0004829|GO:0005524|GO:0005737|GO:0008270 KEGG: 00970+6.1.1.3 AFULGI_00005580 107257c5e188dd29dcb1ea25714d3bee 619 ProDom PD016189 SYNTHETASE LIGASE THREONYL-TRNA AMINOACYL-TRNA NUCLEOTIDE-BINDING BIOSYNTHESIS ATP-BINDING ZINC METAL-BINDING THRRS 1 131 2.0E-70 T 01-11-2018 IPR015011 Threonyl-tRNA synthetase, editing domain, archaea GO:0004829|GO:0005524|GO:0005737|GO:0008270 KEGG: 00970+6.1.1.3 AFULGI_00005580 107257c5e188dd29dcb1ea25714d3bee 619 Pfam PF03129 Anticodon binding domain 502 596 9.1E-24 T 01-11-2018 IPR004154 Anticodon-binding AFULGI_00005580 107257c5e188dd29dcb1ea25714d3bee 619 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 277 481 2.9E-19 T 01-11-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFULGI_00005580 107257c5e188dd29dcb1ea25714d3bee 619 SUPERFAMILY SSF55681 186 509 5.51E-56 T 01-11-2018 AFULGI_00005580 107257c5e188dd29dcb1ea25714d3bee 619 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 32 596 28.913 T 01-11-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 AFULGI_00005580 107257c5e188dd29dcb1ea25714d3bee 619 Gene3D G3DSA:3.30.930.10 192 483 2.6E-60 T 01-11-2018 AFULGI_00005580 107257c5e188dd29dcb1ea25714d3bee 619 Gene3D G3DSA:3.40.50.800 493 602 5.5E-30 T 01-11-2018 IPR036621 Anticodon-binding domain superfamily AFULGI_00005580 107257c5e188dd29dcb1ea25714d3bee 619 Gene3D G3DSA:3.50.80.10 1 131 4.1E-50 T 01-11-2018 IPR023509 D-aminoacyl-tRNA deacylase-like superfamily AFULGI_00005580 107257c5e188dd29dcb1ea25714d3bee 619 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 18 598 1.3E-197 T 01-11-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 AFULGI_00024120 d3ac2121e076d393b7dbe30bf0b6da70 56 SUPERFAMILY SSF54862 6 54 1.73E-18 T 01-11-2018 AFULGI_00024120 d3ac2121e076d393b7dbe30bf0b6da70 56 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 37 48 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFULGI_00024120 d3ac2121e076d393b7dbe30bf0b6da70 56 Pfam PF13187 4Fe-4S dicluster domain 7 51 1.1E-9 T 01-11-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFULGI_00024120 d3ac2121e076d393b7dbe30bf0b6da70 56 Gene3D G3DSA:3.30.70.20 5 54 9.8E-15 T 01-11-2018 AFULGI_00018160 309ddf2baecd82a9419d033c6ce0d96a 294 Gene3D G3DSA:3.40.50.1820 36 274 6.2E-37 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold AFULGI_00018160 309ddf2baecd82a9419d033c6ce0d96a 294 Pfam PF12697 Alpha/beta hydrolase family 41 272 2.2E-10 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 AFULGI_00018160 309ddf2baecd82a9419d033c6ce0d96a 294 SUPERFAMILY SSF53474 19 292 7.74E-40 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold AFULGI_00018160 309ddf2baecd82a9419d033c6ce0d96a 294 Gene3D G3DSA:1.10.10.800 142 223 6.2E-37 T 01-11-2018 AFULGI_00001980 0e6570e2764d8da73848b6251b417c4a 404 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 215 247 - T 01-11-2018 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 AFULGI_00001980 0e6570e2764d8da73848b6251b417c4a 404 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 2 401 40.21 T 01-11-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AFULGI_00001980 0e6570e2764d8da73848b6251b417c4a 404 Pfam PF00815 Histidinol dehydrogenase 8 401 2.4E-154 T 01-11-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AFULGI_00001980 0e6570e2764d8da73848b6251b417c4a 404 Gene3D G3DSA:3.40.50.1980 219 323 1.5E-110 T 01-11-2018 AFULGI_00001980 0e6570e2764d8da73848b6251b417c4a 404 PIRSF PIRSF000099 1 404 3.7E-171 T 01-11-2018 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AFULGI_00001980 0e6570e2764d8da73848b6251b417c4a 404 Gene3D G3DSA:3.40.50.1980 18 217 1.5E-110 T 01-11-2018 AFULGI_00001980 0e6570e2764d8da73848b6251b417c4a 404 PRINTS PR00083 Histidinol dehydrogenase signature 121 147 4.6E-92 T 01-11-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AFULGI_00001980 0e6570e2764d8da73848b6251b417c4a 404 PRINTS PR00083 Histidinol dehydrogenase signature 156 182 4.6E-92 T 01-11-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AFULGI_00001980 0e6570e2764d8da73848b6251b417c4a 404 PRINTS PR00083 Histidinol dehydrogenase signature 294 319 4.6E-92 T 01-11-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AFULGI_00001980 0e6570e2764d8da73848b6251b417c4a 404 PRINTS PR00083 Histidinol dehydrogenase signature 237 256 4.6E-92 T 01-11-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AFULGI_00001980 0e6570e2764d8da73848b6251b417c4a 404 PRINTS PR00083 Histidinol dehydrogenase signature 335 353 4.6E-92 T 01-11-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AFULGI_00001980 0e6570e2764d8da73848b6251b417c4a 404 PRINTS PR00083 Histidinol dehydrogenase signature 186 211 4.6E-92 T 01-11-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AFULGI_00001980 0e6570e2764d8da73848b6251b417c4a 404 PRINTS PR00083 Histidinol dehydrogenase signature 20 44 4.6E-92 T 01-11-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AFULGI_00001980 0e6570e2764d8da73848b6251b417c4a 404 PRINTS PR00083 Histidinol dehydrogenase signature 215 236 4.6E-92 T 01-11-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AFULGI_00001980 0e6570e2764d8da73848b6251b417c4a 404 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 20 400 5.1E-155 T 01-11-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AFULGI_00001980 0e6570e2764d8da73848b6251b417c4a 404 SUPERFAMILY SSF53720 13 401 6.08E-72 T 01-11-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 AFULGI_00023190 505e8d33039d1eda6e78dcba67eb758d 191 SUPERFAMILY SSF53335 16 189 1.29E-39 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFULGI_00023190 505e8d33039d1eda6e78dcba67eb758d 191 PIRSF PIRSF005461 1 191 1.7E-75 T 01-11-2018 IPR015507 Ribosomal RNA large subunit methyltransferase E GO:0001510|GO:0008168 AFULGI_00023190 505e8d33039d1eda6e78dcba67eb758d 191 Gene3D G3DSA:3.40.50.150 13 191 6.8E-61 T 01-11-2018 AFULGI_00023190 505e8d33039d1eda6e78dcba67eb758d 191 Hamap MF_01547 Ribosomal RNA large subunit methyltransferase E [rlmE]. 1 189 29.53 T 01-11-2018 IPR015507 Ribosomal RNA large subunit methyltransferase E GO:0001510|GO:0008168 AFULGI_00023190 505e8d33039d1eda6e78dcba67eb758d 191 Pfam PF01728 FtsJ-like methyltransferase 17 188 1.6E-57 T 01-11-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 AFULGI_00017460 a02601d807c21cc39032a7192c66a5ee 235 SUPERFAMILY SSF51182 12 180 7.27E-24 T 01-11-2018 IPR011051 RmlC-like cupin domain superfamily AFULGI_00017460 a02601d807c21cc39032a7192c66a5ee 235 Gene3D G3DSA:2.60.120.10 4 192 2.1E-49 T 01-11-2018 IPR014710 RmlC-like jelly roll fold AFULGI_00017460 a02601d807c21cc39032a7192c66a5ee 235 Pfam PF06560 Glucose-6-phosphate isomerase (GPI) 14 189 4.5E-81 T 01-11-2018 IPR010551 Glucose-6-phosphate isomerase, prokaryote GO:0004347|GO:0005737|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385 AFULGI_00012250 6f26791c3bd175a4b148ae0596351bf3 125 ProSitePatterns PS00475 Ribosomal protein L15 signature. 72 102 - T 01-11-2018 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00012250 6f26791c3bd175a4b148ae0596351bf3 125 Hamap MF_00329 50S ribosomal protein L18e [rpl18e]. 9 125 27.903 T 01-11-2018 IPR022947 Ribosomal protein L18e, archaea AFULGI_00012250 6f26791c3bd175a4b148ae0596351bf3 125 Gene3D G3DSA:3.100.10.10 9 125 1.3E-38 T 01-11-2018 AFULGI_00012250 6f26791c3bd175a4b148ae0596351bf3 125 SUPERFAMILY SSF52080 11 124 1.01E-28 T 01-11-2018 IPR036227 Ribosomal L18e/L15P superfamily AFULGI_00012250 6f26791c3bd175a4b148ae0596351bf3 125 Pfam PF17135 Ribosomal protein 60S L18 and 50S L18e 27 124 2.0E-11 T 01-11-2018 IPR021131 Ribosomal protein L18e/L15P AFULGI_00002590 0de7c813c4b1a44987458f8cddd719b0 276 SUPERFAMILY SSF103481 36 134 1.07E-16 T 01-11-2018 AFULGI_00002590 0de7c813c4b1a44987458f8cddd719b0 276 Pfam PF00892 EamA-like transporter family 3 132 3.2E-25 T 01-11-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFULGI_00002590 0de7c813c4b1a44987458f8cddd719b0 276 Pfam PF00892 EamA-like transporter family 140 273 8.5E-27 T 01-11-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFULGI_00002590 0de7c813c4b1a44987458f8cddd719b0 276 SUPERFAMILY SSF103481 176 275 1.31E-13 T 01-11-2018 AFULGI_00026090 14a7293b2588b2689d43718f8e51e5f2 494 SUPERFAMILY SSF103473 16 426 2.35E-40 T 01-11-2018 IPR036259 MFS transporter superfamily AFULGI_00026090 14a7293b2588b2689d43718f8e51e5f2 494 Gene3D G3DSA:1.20.1250.20 16 194 2.0E-10 T 01-11-2018 AFULGI_00026090 14a7293b2588b2689d43718f8e51e5f2 494 Pfam PF07690 Major Facilitator Superfamily 22 357 1.7E-20 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFULGI_00026090 14a7293b2588b2689d43718f8e51e5f2 494 Gene3D G3DSA:1.20.1250.20 202 434 2.5E-15 T 01-11-2018 AFULGI_00024340 e59f29325cff72a525a3c7e81b455ca3 187 Pfam PF06742 Protein of unknown function (DUF1214) 68 167 1.1E-23 T 01-11-2018 IPR010621 Domain of unknown function DUF1214 AFULGI_00024340 e59f29325cff72a525a3c7e81b455ca3 187 PIRSF PIRSF009471 1 187 4.3E-81 T 01-11-2018 IPR012038 Uncharacterised conserved protein UCP009471 AFULGI_00024340 e59f29325cff72a525a3c7e81b455ca3 187 Gene3D G3DSA:2.60.120.600 22 181 3.5E-16 T 01-11-2018 IPR037049 Domain of unknown function DUF1214, C-terminal domain superfamily AFULGI_00024340 e59f29325cff72a525a3c7e81b455ca3 187 SUPERFAMILY SSF160935 15 170 2.75E-30 T 01-11-2018 AFULGI_00020330 f420be0ce14beead173e391c17c3a5ac 76 Pfam PF04010 Protein of unknown function (DUF357) 25 71 3.7E-15 T 01-11-2018 IPR023140 Domain of unknown function DUF357 AFULGI_00020330 f420be0ce14beead173e391c17c3a5ac 76 SUPERFAMILY SSF158372 2 72 2.09E-22 T 01-11-2018 IPR036809 AF1782-like superfamily AFULGI_00020330 f420be0ce14beead173e391c17c3a5ac 76 Gene3D G3DSA:1.20.1270.90 1 76 1.1E-36 T 01-11-2018 AFULGI_00001640 eca7547354f2f345c2dd65ba1862af77 77 Pfam PF01206 Sulfurtransferase TusA 12 76 7.7E-19 T 01-11-2018 IPR001455 TusA-like domain AFULGI_00001640 eca7547354f2f345c2dd65ba1862af77 77 SUPERFAMILY SSF64307 10 77 2.75E-17 T 01-11-2018 IPR036868 TusA-like domain superfamily AFULGI_00001640 eca7547354f2f345c2dd65ba1862af77 77 Gene3D G3DSA:3.30.110.40 12 77 5.4E-15 T 01-11-2018 IPR036868 TusA-like domain superfamily AFULGI_00017870 b46dbc9fadbe568da67e4ab54d0aef4d 274 Pfam PF00892 EamA-like transporter family 139 269 3.8E-21 T 01-11-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFULGI_00017870 b46dbc9fadbe568da67e4ab54d0aef4d 274 Pfam PF00892 EamA-like transporter family 3 130 1.8E-23 T 01-11-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFULGI_00017870 b46dbc9fadbe568da67e4ab54d0aef4d 274 SUPERFAMILY SSF103481 32 133 3.53E-11 T 01-11-2018 AFULGI_00017870 b46dbc9fadbe568da67e4ab54d0aef4d 274 SUPERFAMILY SSF103481 174 272 8.24E-14 T 01-11-2018 AFULGI_00010200 4890fe44a34cf2fa75cb0398e387aa6b 654 Pfam PF12727 PBP superfamily domain 436 626 8.4E-61 T 01-11-2018 IPR024370 PBP domain AFULGI_00010200 4890fe44a34cf2fa75cb0398e387aa6b 654 Gene3D G3DSA:2.40.340.10 335 411 4.6E-20 T 01-11-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AFULGI_00010200 4890fe44a34cf2fa75cb0398e387aa6b 654 SUPERFAMILY SSF63867 336 411 5.76E-16 T 01-11-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AFULGI_00010200 4890fe44a34cf2fa75cb0398e387aa6b 654 SUPERFAMILY SSF63882 8 181 4.97E-57 T 01-11-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AFULGI_00010200 4890fe44a34cf2fa75cb0398e387aa6b 654 Gene3D G3DSA:3.40.980.10 182 324 4.2E-109 T 01-11-2018 IPR036425 MoaB/Mog-like domain superfamily AFULGI_00010200 4890fe44a34cf2fa75cb0398e387aa6b 654 SUPERFAMILY SSF53850 435 641 2.0E-21 T 01-11-2018 AFULGI_00010200 4890fe44a34cf2fa75cb0398e387aa6b 654 Pfam PF00994 Probable molybdopterin binding domain 187 324 1.7E-25 T 01-11-2018 IPR001453 MoaB/Mog domain AFULGI_00010200 4890fe44a34cf2fa75cb0398e387aa6b 654 SUPERFAMILY SSF53218 184 329 3.8E-39 T 01-11-2018 IPR036425 MoaB/Mog-like domain superfamily AFULGI_00010200 4890fe44a34cf2fa75cb0398e387aa6b 654 Gene3D G3DSA:3.90.105.10 31 181 4.2E-109 T 01-11-2018 AFULGI_00010200 4890fe44a34cf2fa75cb0398e387aa6b 654 Pfam PF03454 MoeA C-terminal region (domain IV) 338 409 1.5E-18 T 01-11-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AFULGI_00010200 4890fe44a34cf2fa75cb0398e387aa6b 654 Gene3D G3DSA:2.170.190.11 52 148 4.2E-109 T 01-11-2018 AFULGI_00010200 4890fe44a34cf2fa75cb0398e387aa6b 654 Gene3D G3DSA:3.40.190.10 498 606 1.4E-10 T 01-11-2018 AFULGI_00010200 4890fe44a34cf2fa75cb0398e387aa6b 654 ProSitePatterns PS01079 Molybdenum cofactor biosynthesis proteins signature 2. 260 294 - T 01-11-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 AFULGI_00010200 4890fe44a34cf2fa75cb0398e387aa6b 654 Pfam PF03453 MoeA N-terminal region (domain I and II) 10 174 5.3E-46 T 01-11-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AFULGI_00010200 4890fe44a34cf2fa75cb0398e387aa6b 654 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 184 321 7.0E-35 T 01-11-2018 IPR001453 MoaB/Mog domain AFULGI_00010200 4890fe44a34cf2fa75cb0398e387aa6b 654 SMART SM00852 187 325 6.9E-40 T 01-11-2018 IPR001453 MoaB/Mog domain AFULGI_00026150 00a4e383cdb8fe505b7828b27d3d24de 174 TIGRFAM TIGR01527 arch_NMN_Atrans: nicotinamide-nucleotide adenylyltransferase 2 170 6.3E-94 T 01-11-2018 IPR006418 Nicotinamide-nucleotide adenylyltransferase, archaeal type GO:0000309|GO:0005737|GO:0009435 KEGG: 00760+2.7.7.1 AFULGI_00026150 00a4e383cdb8fe505b7828b27d3d24de 174 Hamap MF_00243 Nicotinamide-nucleotide adenylyltransferase. 1 174 90.481 T 01-11-2018 IPR006418 Nicotinamide-nucleotide adenylyltransferase, archaeal type GO:0000309|GO:0005737|GO:0009435 KEGG: 00760+2.7.7.1 AFULGI_00026150 00a4e383cdb8fe505b7828b27d3d24de 174 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 2 60 8.8E-17 T 01-11-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 AFULGI_00026150 00a4e383cdb8fe505b7828b27d3d24de 174 Pfam PF01467 Cytidylyltransferase-like 4 137 1.4E-19 T 01-11-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 AFULGI_00026150 00a4e383cdb8fe505b7828b27d3d24de 174 Gene3D G3DSA:3.40.50.620 1 173 3.9E-51 T 01-11-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFULGI_00026150 00a4e383cdb8fe505b7828b27d3d24de 174 SUPERFAMILY SSF52374 1 167 3.75E-33 T 01-11-2018 AFULGI_00016160 4bd7c9acd054cbf3b4e942cc603a9111 80 Gene3D G3DSA:3.30.160.250 15 78 2.6E-11 T 01-11-2018 AFULGI_00016160 4bd7c9acd054cbf3b4e942cc603a9111 80 Pfam PF15919 HicB_like antitoxin of bacterial toxin-antitoxin system 34 73 2.5E-6 T 01-11-2018 IPR031807 HicB-like antitoxin of toxin-antitoxin system AFULGI_00016160 4bd7c9acd054cbf3b4e942cc603a9111 80 SUPERFAMILY SSF143100 15 71 8.5E-13 T 01-11-2018 IPR035069 TTHA1013/TTHA0281-like AFULGI_00026350 c4375ea35e6bc4297daadbf46d455c80 170 Pfam PF00857 Isochorismatase family 2 146 4.7E-33 T 01-11-2018 IPR000868 Isochorismatase-like GO:0003824 AFULGI_00026350 c4375ea35e6bc4297daadbf46d455c80 170 SUPERFAMILY SSF52499 2 169 2.49E-46 T 01-11-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 AFULGI_00026350 c4375ea35e6bc4297daadbf46d455c80 170 Gene3D G3DSA:3.40.50.850 1 170 6.6E-51 T 01-11-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 AFULGI_00015380 26a29522e18cdf31281268d5093c2a2e 547 SMART SM00873 93 250 3.2E-26 T 01-11-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 AFULGI_00015380 26a29522e18cdf31281268d5093c2a2e 547 Pfam PF03483 B3/4 domain 95 233 1.5E-13 T 01-11-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 AFULGI_00015380 26a29522e18cdf31281268d5093c2a2e 547 Gene3D G3DSA:3.50.40.10 74 269 1.6E-68 T 01-11-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 KEGG: 00970+6.1.1.20 AFULGI_00015380 26a29522e18cdf31281268d5093c2a2e 547 SUPERFAMILY SSF55681 336 540 2.68E-46 T 01-11-2018 AFULGI_00015380 26a29522e18cdf31281268d5093c2a2e 547 Gene3D G3DSA:3.30.930.10 356 541 1.2E-50 T 01-11-2018 AFULGI_00015380 26a29522e18cdf31281268d5093c2a2e 547 Pfam PF03484 tRNA synthetase B5 domain 274 339 5.4E-20 T 01-11-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 AFULGI_00015380 26a29522e18cdf31281268d5093c2a2e 547 SMART SM00874 271 339 2.0E-26 T 01-11-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 AFULGI_00015380 26a29522e18cdf31281268d5093c2a2e 547 Hamap MF_00284 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 538 37.819 T 01-11-2018 IPR022918 Phenylalanine-tRNA ligase beta chain 2, bacterial/archaeal GO:0004826 KEGG: 00970+6.1.1.20 AFULGI_00015380 26a29522e18cdf31281268d5093c2a2e 547 Gene3D G3DSA:3.30.56.10 272 339 9.5E-28 T 01-11-2018 AFULGI_00015380 26a29522e18cdf31281268d5093c2a2e 547 TIGRFAM TIGR00471 pheT_arch: phenylalanine--tRNA ligase, beta subunit 1 541 1.0E-252 T 01-11-2018 IPR004531 Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archae/euk cytosolic GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 AFULGI_00015380 26a29522e18cdf31281268d5093c2a2e 547 SUPERFAMILY SSF46955 7 72 2.47E-9 T 01-11-2018 IPR009061 Putative DNA-binding domain superfamily AFULGI_00015380 26a29522e18cdf31281268d5093c2a2e 547 Gene3D G3DSA:3.30.56.10 1 73 3.7E-15 T 01-11-2018 AFULGI_00015380 26a29522e18cdf31281268d5093c2a2e 547 SUPERFAMILY SSF46955 271 343 2.11E-19 T 01-11-2018 IPR009061 Putative DNA-binding domain superfamily AFULGI_00010560 d715cb37c4675e23981a15d84e959547 176 Gene3D G3DSA:1.10.12.20 21 92 9.3E-26 T 01-11-2018 AFULGI_00010560 d715cb37c4675e23981a15d84e959547 176 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 53 82 5.7E-8 T 01-11-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal AFULGI_00010560 d715cb37c4675e23981a15d84e959547 176 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 89 156 1.3E-14 T 01-11-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal AFULGI_00010560 d715cb37c4675e23981a15d84e959547 176 SUPERFAMILY SSF50249 27 160 1.2E-34 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold AFULGI_00016730 2b3e35bbc997073a100d4d6575087bf2 254 Gene3D G3DSA:3.10.590.10 109 252 9.8E-57 T 01-11-2018 AFULGI_00016730 2b3e35bbc997073a100d4d6575087bf2 254 SUPERFAMILY SSF88697 109 252 2.57E-37 T 01-11-2018 IPR015947 PUA-like superfamily AFULGI_00016730 2b3e35bbc997073a100d4d6575087bf2 254 Pfam PF01878 EVE domain 110 251 4.8E-23 T 01-11-2018 IPR002740 EVE domain AFULGI_00016730 2b3e35bbc997073a100d4d6575087bf2 254 Hamap MF_00771 UPF0310 protein . 109 254 26.313 T 01-11-2018 IPR022996 Uncharacterised protein family UPF0310 AFULGI_00024780 4b53e9bab63836ac642f35a622f01648 148 Pfam PF01467 Cytidylyltransferase-like 5 138 1.4E-21 T 01-11-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 AFULGI_00024780 4b53e9bab63836ac642f35a622f01648 148 Hamap MF_00647 Phosphopantetheine adenylyltransferase [coaD]. 1 148 33.411 T 01-11-2018 IPR023540 Phosphopantetheine adenylyltransferase, archaea GO:0004595 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 AFULGI_00024780 4b53e9bab63836ac642f35a622f01648 148 SUPERFAMILY SSF52374 2 138 6.44E-16 T 01-11-2018 AFULGI_00024780 4b53e9bab63836ac642f35a622f01648 148 Gene3D G3DSA:3.40.50.620 1 148 8.5E-41 T 01-11-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFULGI_00024780 4b53e9bab63836ac642f35a622f01648 148 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 3 44 1.2E-8 T 01-11-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 AFULGI_00014400 291340abeaf7a12fc9ce1a879f619af8 233 SUPERFAMILY SSF51905 2 206 5.05E-13 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFULGI_00014400 291340abeaf7a12fc9ce1a879f619af8 233 Gene3D G3DSA:3.50.50.60 1 86 5.1E-5 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFULGI_00014400 291340abeaf7a12fc9ce1a879f619af8 233 Gene3D G3DSA:3.50.50.60 198 207 6.2E-7 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFULGI_00014400 291340abeaf7a12fc9ce1a879f619af8 233 Gene3D G3DSA:3.50.50.60 102 197 6.2E-7 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFULGI_00016000 c4f37966e1247f862677e31f22cbc72f 499 SUPERFAMILY SSF52540 118 474 2.35E-48 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00016000 c4f37966e1247f862677e31f22cbc72f 499 Gene3D G3DSA:3.40.50.300 234 499 4.4E-89 T 01-11-2018 AFULGI_00016000 c4f37966e1247f862677e31f22cbc72f 499 Gene3D G3DSA:3.30.450.380 18 232 3.1E-63 T 01-11-2018 AFULGI_00016000 c4f37966e1247f862677e31f22cbc72f 499 Pfam PF00437 Type II/IV secretion system protein 138 383 1.9E-41 T 01-11-2018 IPR001482 Type II/IV secretion system protein AFULGI_00013830 dd9bdadc32c2c9b51c2ee31af29f7e32 229 SUPERFAMILY SSF52255 90 223 1.44E-31 T 01-11-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 AFULGI_00013830 dd9bdadc32c2c9b51c2ee31af29f7e32 229 Pfam PF00731 AIR carboxylase 91 224 4.6E-19 T 01-11-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 AFULGI_00013830 dd9bdadc32c2c9b51c2ee31af29f7e32 229 Gene3D G3DSA:3.40.50.7700 91 229 4.2E-38 T 01-11-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 AFULGI_00013830 dd9bdadc32c2c9b51c2ee31af29f7e32 229 SMART SM01001 90 224 3.8E-40 T 01-11-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 AFULGI_00004150 ce571ceeff6cd9fbbe98a77453c649ec 861 Gene3D G3DSA:3.30.450.20 516 640 8.6E-21 T 01-11-2018 AFULGI_00004150 ce571ceeff6cd9fbbe98a77453c649ec 861 Gene3D G3DSA:3.30.450.20 397 515 7.8E-18 T 01-11-2018 AFULGI_00004150 ce571ceeff6cd9fbbe98a77453c649ec 861 Gene3D G3DSA:3.30.450.20 105 198 4.3E-5 T 01-11-2018 AFULGI_00004150 ce571ceeff6cd9fbbe98a77453c649ec 861 SMART SM00086 602 642 2.2 T 01-11-2018 IPR001610 PAC motif AFULGI_00004150 ce571ceeff6cd9fbbe98a77453c649ec 861 SMART SM00086 354 396 9.7E-8 T 01-11-2018 IPR001610 PAC motif AFULGI_00004150 ce571ceeff6cd9fbbe98a77453c649ec 861 Pfam PF08448 PAS fold 425 517 9.5E-7 T 01-11-2018 IPR013656 PAS fold-4 AFULGI_00004150 ce571ceeff6cd9fbbe98a77453c649ec 861 Pfam PF13188 PAS domain 202 242 0.067 T 01-11-2018 IPR000014 PAS domain AFULGI_00004150 ce571ceeff6cd9fbbe98a77453c649ec 861 SMART SM00091 408 472 2.4E-4 T 01-11-2018 IPR000014 PAS domain AFULGI_00004150 ce571ceeff6cd9fbbe98a77453c649ec 861 SMART SM00091 529 595 2.5E-5 T 01-11-2018 IPR000014 PAS domain AFULGI_00004150 ce571ceeff6cd9fbbe98a77453c649ec 861 SMART SM00091 284 349 4.0E-9 T 01-11-2018 IPR000014 PAS domain AFULGI_00004150 ce571ceeff6cd9fbbe98a77453c649ec 861 SMART SM00091 200 266 140.0 T 01-11-2018 IPR000014 PAS domain AFULGI_00004150 ce571ceeff6cd9fbbe98a77453c649ec 861 SMART SM00091 93 159 16.0 T 01-11-2018 IPR000014 PAS domain AFULGI_00004150 ce571ceeff6cd9fbbe98a77453c649ec 861 SUPERFAMILY SSF55785 514 640 2.44E-20 T 01-11-2018 IPR035965 PAS domain superfamily AFULGI_00004150 ce571ceeff6cd9fbbe98a77453c649ec 861 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 405 524 9.4E-17 T 01-11-2018 IPR000014 PAS domain AFULGI_00004150 ce571ceeff6cd9fbbe98a77453c649ec 861 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 281 403 4.4E-33 T 01-11-2018 IPR000014 PAS domain AFULGI_00004150 ce571ceeff6cd9fbbe98a77453c649ec 861 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 525 649 7.6E-31 T 01-11-2018 IPR000014 PAS domain AFULGI_00004150 ce571ceeff6cd9fbbe98a77453c649ec 861 SUPERFAMILY SSF55785 290 398 4.03E-27 T 01-11-2018 IPR035965 PAS domain superfamily AFULGI_00004150 ce571ceeff6cd9fbbe98a77453c649ec 861 SUPERFAMILY SSF55781 642 771 6.38E-5 T 01-11-2018 AFULGI_00004150 ce571ceeff6cd9fbbe98a77453c649ec 861 Pfam PF00989 PAS fold 530 630 1.2E-9 T 01-11-2018 IPR013767 PAS fold GO:0006355 AFULGI_00004150 ce571ceeff6cd9fbbe98a77453c649ec 861 SMART SM00388 795 856 1.2E-4 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFULGI_00004150 ce571ceeff6cd9fbbe98a77453c649ec 861 SUPERFAMILY SSF55785 393 515 1.92E-18 T 01-11-2018 IPR035965 PAS domain superfamily AFULGI_00004150 ce571ceeff6cd9fbbe98a77453c649ec 861 Gene3D G3DSA:3.30.450.20 280 396 1.2E-29 T 01-11-2018 AFULGI_00004150 ce571ceeff6cd9fbbe98a77453c649ec 861 Pfam PF13426 PAS domain 295 395 2.7E-18 T 01-11-2018 IPR000014 PAS domain AFULGI_00004150 ce571ceeff6cd9fbbe98a77453c649ec 861 Pfam PF13426 PAS domain 108 176 0.0023 T 01-11-2018 IPR000014 PAS domain AFULGI_00004650 6e170f48ea6f331cc6d1fa5a23e3a240 721 Gene3D G3DSA:1.20.1640.10 170 357 1.0E-13 T 01-11-2018 AFULGI_00004650 6e170f48ea6f331cc6d1fa5a23e3a240 721 SUPERFAMILY SSF82866 514 709 3.14E-33 T 01-11-2018 AFULGI_00004650 6e170f48ea6f331cc6d1fa5a23e3a240 721 TIGRFAM TIGR00921 2A067: efflux transporter, putative, hydrophobe/amphiphile efflux-3 (HAE3) family 9 708 4.5E-178 T 01-11-2018 IPR004767 Hydrophobe/amphiphile efflux-3 HAE3 AFULGI_00004650 6e170f48ea6f331cc6d1fa5a23e3a240 721 Gene3D G3DSA:1.20.1640.10 524 714 1.6E-14 T 01-11-2018 AFULGI_00004650 6e170f48ea6f331cc6d1fa5a23e3a240 721 SUPERFAMILY SSF82866 135 349 2.22E-31 T 01-11-2018 AFULGI_00004650 6e170f48ea6f331cc6d1fa5a23e3a240 721 Pfam PF03176 MMPL family 494 708 2.8E-30 T 01-11-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 AFULGI_00004650 6e170f48ea6f331cc6d1fa5a23e3a240 721 Pfam PF03176 MMPL family 122 348 4.2E-24 T 01-11-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 AFULGI_00002790 4df1ff3c5f1c4c90772a09def80fce0f 658 ProSitePatterns PS00067 3-hydroxyacyl-CoA dehydrogenase signature. 185 210 - T 01-11-2018 IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved site GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 AFULGI_00002790 4df1ff3c5f1c4c90772a09def80fce0f 658 Gene3D G3DSA:3.40.50.720 3 189 3.0E-77 T 01-11-2018 AFULGI_00002790 4df1ff3c5f1c4c90772a09def80fce0f 658 SUPERFAMILY SSF52096 400 657 9.52E-90 T 01-11-2018 IPR029045 ClpP/crotonase-like domain superfamily AFULGI_00002790 4df1ff3c5f1c4c90772a09def80fce0f 658 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 188 278 4.8E-28 T 01-11-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 AFULGI_00002790 4df1ff3c5f1c4c90772a09def80fce0f 658 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 297 388 3.7E-22 T 01-11-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 AFULGI_00002790 4df1ff3c5f1c4c90772a09def80fce0f 658 Gene3D G3DSA:1.10.1040.10 190 296 1.5E-27 T 01-11-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AFULGI_00002790 4df1ff3c5f1c4c90772a09def80fce0f 658 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 499 519 - T 01-11-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 AFULGI_00002790 4df1ff3c5f1c4c90772a09def80fce0f 658 Gene3D G3DSA:3.90.226.10 387 600 2.5E-74 T 01-11-2018 AFULGI_00002790 4df1ff3c5f1c4c90772a09def80fce0f 658 SUPERFAMILY SSF48179 297 401 1.11E-25 T 01-11-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AFULGI_00002790 4df1ff3c5f1c4c90772a09def80fce0f 658 SUPERFAMILY SSF48179 188 286 2.3E-26 T 01-11-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AFULGI_00002790 4df1ff3c5f1c4c90772a09def80fce0f 658 Gene3D G3DSA:1.10.1040.10 299 384 2.3E-27 T 01-11-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AFULGI_00002790 4df1ff3c5f1c4c90772a09def80fce0f 658 Gene3D G3DSA:1.10.12.10 601 658 6.2E-16 T 01-11-2018 IPR014748 Enoyl-CoA hydratase, C-terminal AFULGI_00002790 4df1ff3c5f1c4c90772a09def80fce0f 658 SUPERFAMILY SSF51735 1 184 1.58E-66 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily AFULGI_00002790 4df1ff3c5f1c4c90772a09def80fce0f 658 Pfam PF00378 Enoyl-CoA hydratase/isomerase 404 657 2.4E-66 T 01-11-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 AFULGI_00002790 4df1ff3c5f1c4c90772a09def80fce0f 658 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 5 185 1.0E-71 T 01-11-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 AFULGI_00012390 e3d7965654a4f42837e225c2da4f860c 434 PIRSF PIRSF018875 1 431 5.3E-125 T 01-11-2018 IPR018646 Membrane protein of 12 TMs AFULGI_00012390 e3d7965654a4f42837e225c2da4f860c 434 Pfam PF09847 Membrane protein of 12 TMs 26 430 5.1E-115 T 01-11-2018 IPR018646 Membrane protein of 12 TMs AFULGI_00011290 155e9938f1700b1ca141de92f0fd1076 371 PIRSF PIRSF018871 1 196 2.2E-74 T 01-11-2018 IPR016738 DNA double-strand break repair nuclease NurA-like AFULGI_00011290 155e9938f1700b1ca141de92f0fd1076 371 PIRSF PIRSF018871 193 370 4.0E-71 T 01-11-2018 IPR016738 DNA double-strand break repair nuclease NurA-like AFULGI_00011290 155e9938f1700b1ca141de92f0fd1076 371 Pfam PF09376 NurA domain 44 338 3.5E-50 T 01-11-2018 IPR018977 NurA domain AFULGI_00011290 155e9938f1700b1ca141de92f0fd1076 371 SMART SM00933 43 338 1.9E-36 T 01-11-2018 IPR018977 NurA domain AFULGI_00017300 488e7f05411195e19aba9453a99ca344 71 Pfam PF02697 Putative antitoxin 4 65 7.0E-21 T 01-11-2018 IPR003847 Putative antitoxin AFULGI_00017300 488e7f05411195e19aba9453a99ca344 71 ProDom PD188822 UPF0330 AF1997 ST1125.1 AF1689 AF1478 C1_0043 PYRAB04040 PF1222 MM2475 MA1514 4 65 4.0E-27 T 01-11-2018 IPR003847 Putative antitoxin AFULGI_00017300 488e7f05411195e19aba9453a99ca344 71 Hamap MF_00794 Putative antitoxin . 3 71 12.998 T 01-11-2018 IPR003847 Putative antitoxin AFULGI_00014890 83e1edc20265e94354afe8fed9f0dcbc 659 Gene3D G3DSA:3.50.50.60 423 578 5.1E-7 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFULGI_00014890 83e1edc20265e94354afe8fed9f0dcbc 659 Pfam PF12838 4Fe-4S dicluster domain 239 321 7.2E-10 T 01-11-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFULGI_00014890 83e1edc20265e94354afe8fed9f0dcbc 659 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 240 251 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFULGI_00014890 83e1edc20265e94354afe8fed9f0dcbc 659 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 598 609 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFULGI_00014890 83e1edc20265e94354afe8fed9f0dcbc 659 Gene3D G3DSA:3.30.70.20 617 657 3.1E-6 T 01-11-2018 AFULGI_00014890 83e1edc20265e94354afe8fed9f0dcbc 659 Gene3D G3DSA:3.50.50.60 130 237 1.1E-12 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFULGI_00014890 83e1edc20265e94354afe8fed9f0dcbc 659 Gene3D G3DSA:3.30.70.20 238 325 1.7E-14 T 01-11-2018 AFULGI_00014890 83e1edc20265e94354afe8fed9f0dcbc 659 Pfam PF12831 FAD dependent oxidoreductase 141 176 4.2E-8 T 01-11-2018 IPR039649 Digeranylgeranylglycerophospholipid reductase, N-terminal AFULGI_00014890 83e1edc20265e94354afe8fed9f0dcbc 659 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 626 637 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFULGI_00014890 83e1edc20265e94354afe8fed9f0dcbc 659 Pfam PF14697 4Fe-4S dicluster domain 591 641 7.5E-9 T 01-11-2018 AFULGI_00014890 83e1edc20265e94354afe8fed9f0dcbc 659 Gene3D G3DSA:3.30.70.20 579 616 3.4E-8 T 01-11-2018 AFULGI_00014890 83e1edc20265e94354afe8fed9f0dcbc 659 SUPERFAMILY SSF54862 232 643 4.49E-25 T 01-11-2018 AFULGI_00014890 83e1edc20265e94354afe8fed9f0dcbc 659 SUPERFAMILY SSF51971 140 580 4.59E-28 T 01-11-2018 AFULGI_00021710 c0ec2f1020eff33abc80bdbda6a2d24f 178 ProSitePatterns PS00358 Ribosomal protein L5 signature. 44 60 - T 01-11-2018 IPR020929 Ribosomal protein L5, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00021710 c0ec2f1020eff33abc80bdbda6a2d24f 178 PIRSF PIRSF002161 1 175 1.1E-52 T 01-11-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00021710 c0ec2f1020eff33abc80bdbda6a2d24f 178 SUPERFAMILY SSF55282 14 171 3.06E-51 T 01-11-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00021710 c0ec2f1020eff33abc80bdbda6a2d24f 178 Hamap MF_01333_A 50S ribosomal protein L5 [rplE]. 13 178 38.029 T 01-11-2018 IPR022804 Ribosomal protein L5, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFULGI_00021710 c0ec2f1020eff33abc80bdbda6a2d24f 178 Gene3D G3DSA:3.30.1440.10 6 178 2.4E-65 T 01-11-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00021710 c0ec2f1020eff33abc80bdbda6a2d24f 178 Pfam PF00673 ribosomal L5P family C-terminus 72 168 1.3E-20 T 01-11-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00021710 c0ec2f1020eff33abc80bdbda6a2d24f 178 Pfam PF00281 Ribosomal protein L5 14 67 5.1E-19 T 01-11-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00026810 47e123da65ef1dabf0b8a498d2414cf7 384 Pfam PF02803 Thiolase, C-terminal domain 259 377 1.3E-9 T 01-11-2018 IPR020617 Thiolase, C-terminal GO:0016747 AFULGI_00026810 47e123da65ef1dabf0b8a498d2414cf7 384 Gene3D G3DSA:3.40.47.10 3 384 6.2E-127 T 01-11-2018 IPR016039 Thiolase-like GO:0003824 AFULGI_00026810 47e123da65ef1dabf0b8a498d2414cf7 384 PIRSF PIRSF000429 1 383 2.9E-68 T 01-11-2018 IPR002155 Thiolase GO:0016747 AFULGI_00026810 47e123da65ef1dabf0b8a498d2414cf7 384 SUPERFAMILY SSF53901 231 381 2.5E-29 T 01-11-2018 IPR016039 Thiolase-like GO:0003824 AFULGI_00026810 47e123da65ef1dabf0b8a498d2414cf7 384 Pfam PF00108 Thiolase, N-terminal domain 4 224 7.4E-24 T 01-11-2018 IPR020616 Thiolase, N-terminal GO:0016747 AFULGI_00026810 47e123da65ef1dabf0b8a498d2414cf7 384 SUPERFAMILY SSF53901 4 228 9.2E-44 T 01-11-2018 IPR016039 Thiolase-like GO:0003824 AFULGI_00015150 51a852e96b4c363b714342526cb017e4 219 SUPERFAMILY SSF52172 80 217 2.09E-60 T 01-11-2018 IPR011006 CheY-like superfamily AFULGI_00015150 51a852e96b4c363b714342526cb017e4 219 Gene3D G3DSA:3.30.70.260 1 78 1.0E-35 T 01-11-2018 AFULGI_00015150 51a852e96b4c363b714342526cb017e4 219 Gene3D G3DSA:3.40.50.10550 79 219 8.4E-72 T 01-11-2018 AFULGI_00015150 51a852e96b4c363b714342526cb017e4 219 PIRSF PIRSF006363 1 219 6.1E-116 T 01-11-2018 IPR015832 Uncharacterised conserved protein UCP006363, ACT-type AFULGI_00015150 51a852e96b4c363b714342526cb017e4 219 Pfam PF01842 ACT domain 5 66 9.4E-7 T 01-11-2018 IPR002912 ACT domain AFULGI_00015150 51a852e96b4c363b714342526cb017e4 219 SUPERFAMILY SSF55021 5 75 1.68E-14 T 01-11-2018 AFULGI_00021810 b439a8c149e5bda1c1c085591e077ea1 237 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 90 220 1.4E-46 T 01-11-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 AFULGI_00021810 b439a8c149e5bda1c1c085591e077ea1 237 Gene3D G3DSA:4.10.950.10 160 237 1.3E-39 T 01-11-2018 IPR014726 Ribosomal protein L2, domain 3 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00021810 b439a8c149e5bda1c1c085591e077ea1 237 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 11 81 1.3E-17 T 01-11-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFULGI_00021810 b439a8c149e5bda1c1c085591e077ea1 237 SUPERFAMILY SSF50249 1 88 8.57E-21 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold AFULGI_00021810 b439a8c149e5bda1c1c085591e077ea1 237 SMART SM01382 88 221 1.8E-72 T 01-11-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 AFULGI_00021810 b439a8c149e5bda1c1c085591e077ea1 237 Hamap MF_01320_A 50S ribosomal protein L2 [rplB]. 1 236 43.533 T 01-11-2018 IPR023672 Ribosomal protein L2, archaeal-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00021810 b439a8c149e5bda1c1c085591e077ea1 237 ProSitePatterns PS00467 Ribosomal protein L2 signature. 187 198 - T 01-11-2018 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00021810 b439a8c149e5bda1c1c085591e077ea1 237 Gene3D G3DSA:2.30.30.30 82 159 4.3E-30 T 01-11-2018 IPR014722 Ribosomal protein L2, domain 2 AFULGI_00021810 b439a8c149e5bda1c1c085591e077ea1 237 SMART SM01383 11 82 9.3E-23 T 01-11-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFULGI_00021810 b439a8c149e5bda1c1c085591e077ea1 237 SUPERFAMILY SSF50104 91 235 1.08E-53 T 01-11-2018 IPR008991 Translation protein SH3-like domain superfamily AFULGI_00021810 b439a8c149e5bda1c1c085591e077ea1 237 Gene3D G3DSA:2.40.50.140 1 78 4.0E-26 T 01-11-2018 AFULGI_00021810 b439a8c149e5bda1c1c085591e077ea1 237 PIRSF PIRSF002158 1 237 8.4E-74 T 01-11-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFULGI_00003650 3432d707167c4f5528277388cd0a33a9 621 Pfam PF13654 AAA domain 168 395 2.0E-25 T 01-11-2018 AFULGI_00003650 3432d707167c4f5528277388cd0a33a9 621 SUPERFAMILY SSF52540 23 399 2.11E-34 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00003650 3432d707167c4f5528277388cd0a33a9 621 SUPERFAMILY SSF54211 426 599 4.93E-42 T 01-11-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFULGI_00003650 3432d707167c4f5528277388cd0a33a9 621 SMART SM00382 46 304 4.4E-9 T 01-11-2018 IPR003593 AAA+ ATPase domain AFULGI_00003650 3432d707167c4f5528277388cd0a33a9 621 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 503 522 1.1E-29 T 01-11-2018 AFULGI_00003650 3432d707167c4f5528277388cd0a33a9 621 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 54 73 1.1E-29 T 01-11-2018 AFULGI_00003650 3432d707167c4f5528277388cd0a33a9 621 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 426 442 1.1E-29 T 01-11-2018 AFULGI_00003650 3432d707167c4f5528277388cd0a33a9 621 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 533 552 1.1E-29 T 01-11-2018 AFULGI_00003650 3432d707167c4f5528277388cd0a33a9 621 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 556 574 1.1E-29 T 01-11-2018 AFULGI_00003650 3432d707167c4f5528277388cd0a33a9 621 Gene3D G3DSA:3.40.50.300 10 121 9.0E-31 T 01-11-2018 AFULGI_00003650 3432d707167c4f5528277388cd0a33a9 621 Gene3D G3DSA:3.40.50.300 155 306 7.9E-39 T 01-11-2018 AFULGI_00003650 3432d707167c4f5528277388cd0a33a9 621 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 409 601 1.6E-30 T 01-11-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 AFULGI_00003650 3432d707167c4f5528277388cd0a33a9 621 TIGRFAM TIGR00764 lon_rel: putative ATP-dependent protease 11 615 0.0 T 01-11-2018 IPR004663 Lon protease, archaeal GO:0004176|GO:0005524|GO:0030163 AFULGI_00003650 3432d707167c4f5528277388cd0a33a9 621 Pfam PF01078 Magnesium chelatase, subunit ChlI 28 80 7.1E-11 T 01-11-2018 IPR000523 Magnesium chelatase ChlI domain AFULGI_00003650 3432d707167c4f5528277388cd0a33a9 621 Gene3D G3DSA:1.10.8.60 307 399 1.9E-41 T 01-11-2018 AFULGI_00003650 3432d707167c4f5528277388cd0a33a9 621 Gene3D G3DSA:3.30.230.10 415 621 3.3E-79 T 01-11-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AFULGI_00014020 b589b27e138925573c4fb35ed89287a3 136 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 45 110 7.2E-19 T 01-11-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal AFULGI_00014020 b589b27e138925573c4fb35ed89287a3 136 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 7 43 2.5E-12 T 01-11-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal AFULGI_00014020 b589b27e138925573c4fb35ed89287a3 136 Gene3D G3DSA:1.10.12.20 3 47 1.0E-9 T 01-11-2018 AFULGI_00014020 b589b27e138925573c4fb35ed89287a3 136 SUPERFAMILY SSF50249 6 118 2.23E-30 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold AFULGI_00023100 f3a10215442befad3e4e4bc952cbfe54 219 Gene3D G3DSA:3.40.1160.10 1 219 1.2E-66 T 01-11-2018 IPR036393 Acetylglutamate kinase-like superfamily AFULGI_00023100 f3a10215442befad3e4e4bc952cbfe54 219 TIGRFAM TIGR02076 pyrH_arch: putative uridylate kinase 3 218 2.3E-91 T 01-11-2018 IPR011818 Uridylate kinase, archaeal/spirochete, putative GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 AFULGI_00023100 f3a10215442befad3e4e4bc952cbfe54 219 PIRSF PIRSF005650 1 219 1.4E-59 T 01-11-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 AFULGI_00023100 f3a10215442befad3e4e4bc952cbfe54 219 Pfam PF00696 Amino acid kinase family 1 198 7.6E-30 T 01-11-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 AFULGI_00023100 f3a10215442befad3e4e4bc952cbfe54 219 Hamap MF_01220_A Uridylate kinase [pyrH]. 1 219 34.453 T 01-11-2018 IPR011818 Uridylate kinase, archaeal/spirochete, putative GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 AFULGI_00023100 f3a10215442befad3e4e4bc952cbfe54 219 SUPERFAMILY SSF53633 1 218 7.72E-42 T 01-11-2018 IPR036393 Acetylglutamate kinase-like superfamily AFULGI_00004420 7fe80e0eacfd4a15f762ed5059d9df0d 387 Pfam PF02803 Thiolase, C-terminal domain 259 360 7.4E-6 T 01-11-2018 IPR020617 Thiolase, C-terminal GO:0016747 AFULGI_00004420 7fe80e0eacfd4a15f762ed5059d9df0d 387 SUPERFAMILY SSF53901 228 384 2.27E-27 T 01-11-2018 IPR016039 Thiolase-like GO:0003824 AFULGI_00004420 7fe80e0eacfd4a15f762ed5059d9df0d 387 Gene3D G3DSA:3.40.47.10 2 387 1.8E-124 T 01-11-2018 IPR016039 Thiolase-like GO:0003824 AFULGI_00004420 7fe80e0eacfd4a15f762ed5059d9df0d 387 SUPERFAMILY SSF53901 3 229 3.02E-48 T 01-11-2018 IPR016039 Thiolase-like GO:0003824 AFULGI_00004420 7fe80e0eacfd4a15f762ed5059d9df0d 387 PIRSF PIRSF000429 1 385 1.0E-62 T 01-11-2018 IPR002155 Thiolase GO:0016747 AFULGI_00004420 7fe80e0eacfd4a15f762ed5059d9df0d 387 Pfam PF00108 Thiolase, N-terminal domain 14 222 6.1E-28 T 01-11-2018 IPR020616 Thiolase, N-terminal GO:0016747 AFULGI_00004040 af2cf596367e67b4d6a871673ef845a4 551 SMART SM00450 459 551 3.5E-19 T 01-11-2018 IPR001763 Rhodanese-like domain AFULGI_00004040 af2cf596367e67b4d6a871673ef845a4 551 Gene3D G3DSA:3.40.250.10 455 551 8.6E-24 T 01-11-2018 IPR036873 Rhodanese-like domain superfamily AFULGI_00004040 af2cf596367e67b4d6a871673ef845a4 551 SUPERFAMILY SSF52821 448 550 7.33E-24 T 01-11-2018 IPR036873 Rhodanese-like domain superfamily AFULGI_00004040 af2cf596367e67b4d6a871673ef845a4 551 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 240 256 5.3E-28 T 01-11-2018 AFULGI_00004040 af2cf596367e67b4d6a871673ef845a4 551 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 5.3E-28 T 01-11-2018 AFULGI_00004040 af2cf596367e67b4d6a871673ef845a4 551 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 109 127 5.3E-28 T 01-11-2018 AFULGI_00004040 af2cf596367e67b4d6a871673ef845a4 551 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 155 173 5.3E-28 T 01-11-2018 AFULGI_00004040 af2cf596367e67b4d6a871673ef845a4 551 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 267 289 5.3E-28 T 01-11-2018 AFULGI_00004040 af2cf596367e67b4d6a871673ef845a4 551 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 334 438 5.5E-18 T 01-11-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 AFULGI_00004040 af2cf596367e67b4d6a871673ef845a4 551 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 2 24 5.5E-19 T 01-11-2018 AFULGI_00004040 af2cf596367e67b4d6a871673ef845a4 551 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 241 255 5.5E-19 T 01-11-2018 AFULGI_00004040 af2cf596367e67b4d6a871673ef845a4 551 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 282 289 5.5E-19 T 01-11-2018 AFULGI_00004040 af2cf596367e67b4d6a871673ef845a4 551 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 155 180 5.5E-19 T 01-11-2018 AFULGI_00004040 af2cf596367e67b4d6a871673ef845a4 551 Gene3D G3DSA:3.50.50.60 118 444 1.8E-167 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFULGI_00004040 af2cf596367e67b4d6a871673ef845a4 551 Gene3D G3DSA:3.50.50.60 3 345 1.8E-167 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFULGI_00004040 af2cf596367e67b4d6a871673ef845a4 551 SUPERFAMILY SSF51905 1 320 4.04E-51 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFULGI_00004040 af2cf596367e67b4d6a871673ef845a4 551 Pfam PF00581 Rhodanese-like domain 463 550 2.7E-13 T 01-11-2018 IPR001763 Rhodanese-like domain AFULGI_00004040 af2cf596367e67b4d6a871673ef845a4 551 SUPERFAMILY SSF55424 328 452 6.01E-34 T 01-11-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 AFULGI_00004040 af2cf596367e67b4d6a871673ef845a4 551 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 289 6.3E-67 T 01-11-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFULGI_00022680 50e16d996c4efa6c4fb8d3448ee6f047 367 TIGRFAM TIGR03812 tyr_de_CO2_Arch: tyrosine decarboxylase MnfA 2 364 1.2E-163 T 01-11-2018 IPR020931 Decarboxylase MfnA, archaea GO:0016831 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 AFULGI_00022680 50e16d996c4efa6c4fb8d3448ee6f047 367 SUPERFAMILY SSF53383 15 366 4.03E-99 T 01-11-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFULGI_00022680 50e16d996c4efa6c4fb8d3448ee6f047 367 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 54 315 9.5E-32 T 01-11-2018 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 AFULGI_00022680 50e16d996c4efa6c4fb8d3448ee6f047 367 ProSitePatterns PS00392 DDC / GAD / HDC / TyrDC pyridoxal-phosphate attachment site. 209 230 - T 01-11-2018 IPR021115 Pyridoxal-phosphate binding site GO:0016831 AFULGI_00022680 50e16d996c4efa6c4fb8d3448ee6f047 367 Gene3D G3DSA:3.40.640.10 29 273 4.0E-124 T 01-11-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFULGI_00022680 50e16d996c4efa6c4fb8d3448ee6f047 367 Hamap MF_01610 Probable L-tyrosine/L-aspartate decarboxylase [mfnA]. 5 365 57.94 T 01-11-2018 IPR020931 Decarboxylase MfnA, archaea GO:0016831 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 AFULGI_00022680 50e16d996c4efa6c4fb8d3448ee6f047 367 Gene3D G3DSA:3.90.1150.10 2 358 4.0E-124 T 01-11-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFULGI_00024090 8657ca3ed864de16bd00f4dea2c82eef 182 Gene3D G3DSA:3.30.420.470 2 172 5.0E-23 T 01-11-2018 AFULGI_00024090 8657ca3ed864de16bd00f4dea2c82eef 182 Pfam PF13358 DDE superfamily endonuclease 12 148 4.7E-28 T 01-11-2018 IPR038717 Tc1-like transposase, DDE domain AFULGI_00024090 8657ca3ed864de16bd00f4dea2c82eef 182 SUPERFAMILY SSF53098 56 149 5.5E-7 T 01-11-2018 IPR012337 Ribonuclease H-like superfamily AFULGI_00011020 8657ca3ed864de16bd00f4dea2c82eef 182 Gene3D G3DSA:3.30.420.470 2 172 5.0E-23 T 01-11-2018 AFULGI_00011020 8657ca3ed864de16bd00f4dea2c82eef 182 Pfam PF13358 DDE superfamily endonuclease 12 148 4.7E-28 T 01-11-2018 IPR038717 Tc1-like transposase, DDE domain AFULGI_00011020 8657ca3ed864de16bd00f4dea2c82eef 182 SUPERFAMILY SSF53098 56 149 5.5E-7 T 01-11-2018 IPR012337 Ribonuclease H-like superfamily AFULGI_00014630 8657ca3ed864de16bd00f4dea2c82eef 182 Gene3D G3DSA:3.30.420.470 2 172 5.0E-23 T 01-11-2018 AFULGI_00014630 8657ca3ed864de16bd00f4dea2c82eef 182 Pfam PF13358 DDE superfamily endonuclease 12 148 4.7E-28 T 01-11-2018 IPR038717 Tc1-like transposase, DDE domain AFULGI_00014630 8657ca3ed864de16bd00f4dea2c82eef 182 SUPERFAMILY SSF53098 56 149 5.5E-7 T 01-11-2018 IPR012337 Ribonuclease H-like superfamily AFULGI_00011250 942fc31079b1abc57976cb512b83e9d9 589 Gene3D G3DSA:3.30.300.310 484 588 2.0E-31 T 01-11-2018 AFULGI_00011250 942fc31079b1abc57976cb512b83e9d9 589 SUPERFAMILY SSF56801 23 584 3.53E-149 T 01-11-2018 AFULGI_00011250 942fc31079b1abc57976cb512b83e9d9 589 Gene3D G3DSA:3.40.50.12780 16 239 2.1E-54 T 01-11-2018 AFULGI_00011250 942fc31079b1abc57976cb512b83e9d9 589 Pfam PF13193 AMP-binding enzyme C-terminal domain 497 574 2.7E-21 T 01-11-2018 IPR025110 AMP-binding enzyme, C-terminal domain AFULGI_00011250 942fc31079b1abc57976cb512b83e9d9 589 Pfam PF00501 AMP-binding enzyme 37 488 3.4E-104 T 01-11-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFULGI_00011250 942fc31079b1abc57976cb512b83e9d9 589 ProSitePatterns PS00455 Putative AMP-binding domain signature. 196 207 - T 01-11-2018 IPR020845 AMP-binding, conserved site AFULGI_00011250 942fc31079b1abc57976cb512b83e9d9 589 Gene3D G3DSA:2.30.38.10 400 481 1.6E-66 T 01-11-2018 AFULGI_00011250 942fc31079b1abc57976cb512b83e9d9 589 Gene3D G3DSA:3.40.50.980 271 399 1.6E-66 T 01-11-2018 AFULGI_00014550 ad5fa7d2e0f4d633b7d79c1c1fbf1ad3 307 SUPERFAMILY SSF56281 2 242 1.05E-41 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFULGI_00014550 ad5fa7d2e0f4d633b7d79c1c1fbf1ad3 307 Pfam PF00753 Metallo-beta-lactamase superfamily 26 216 1.3E-21 T 01-11-2018 IPR001279 Metallo-beta-lactamase AFULGI_00014550 ad5fa7d2e0f4d633b7d79c1c1fbf1ad3 307 SMART SM00849 25 216 1.2E-32 T 01-11-2018 IPR001279 Metallo-beta-lactamase AFULGI_00014550 ad5fa7d2e0f4d633b7d79c1c1fbf1ad3 307 Gene3D G3DSA:3.60.15.10 7 264 3.9E-56 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFULGI_00023250 cf9a57788860bb8168662a4795eccc70 384 Gene3D G3DSA:1.20.140.10 238 383 1.5E-57 T 01-11-2018 AFULGI_00023250 cf9a57788860bb8168662a4795eccc70 384 SUPERFAMILY SSF47203 230 383 1.19E-59 T 01-11-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 AFULGI_00023250 cf9a57788860bb8168662a4795eccc70 384 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 231 379 4.8E-56 T 01-11-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AFULGI_00023250 cf9a57788860bb8168662a4795eccc70 384 Gene3D G3DSA:1.10.540.10 1 120 9.7E-38 T 01-11-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 AFULGI_00023250 cf9a57788860bb8168662a4795eccc70 384 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 117 9.2E-32 T 01-11-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 AFULGI_00023250 cf9a57788860bb8168662a4795eccc70 384 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 124 219 3.5E-29 T 01-11-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 AFULGI_00023250 cf9a57788860bb8168662a4795eccc70 384 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 338 357 - T 01-11-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 AFULGI_00023250 cf9a57788860bb8168662a4795eccc70 384 SUPERFAMILY SSF56645 1 242 3.14E-78 T 01-11-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 AFULGI_00023250 cf9a57788860bb8168662a4795eccc70 384 PIRSF PIRSF016578 3 382 9.5E-21 T 01-11-2018 AFULGI_00023250 cf9a57788860bb8168662a4795eccc70 384 Gene3D G3DSA:2.40.110.10 121 237 2.0E-43 T 01-11-2018 AFULGI_00023330 359622d7fcf7243f3f19191ba28c4912 215 Pfam PF01912 eIF-6 family 2 195 7.0E-61 T 01-11-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 AFULGI_00023330 359622d7fcf7243f3f19191ba28c4912 215 SMART SM00654 1 195 1.8E-95 T 01-11-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 AFULGI_00023330 359622d7fcf7243f3f19191ba28c4912 215 Hamap MF_00032 Translation initiation factor 6 [eif6]. 1 215 70.904 T 01-11-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 AFULGI_00023330 359622d7fcf7243f3f19191ba28c4912 215 PIRSF PIRSF006413 1 215 2.3E-73 T 01-11-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 AFULGI_00023330 359622d7fcf7243f3f19191ba28c4912 215 SUPERFAMILY SSF55909 2 213 3.24E-61 T 01-11-2018 AFULGI_00023330 359622d7fcf7243f3f19191ba28c4912 215 Gene3D G3DSA:3.75.10.10 1 214 7.9E-65 T 01-11-2018 AFULGI_00023330 359622d7fcf7243f3f19191ba28c4912 215 TIGRFAM TIGR00323 eIF-6: putative translation initiation factor eIF-6 2 214 1.9E-97 T 01-11-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 AFULGI_00003720 54d3db477aa8957a2c1e7799869ec039 227 TIGRFAM TIGR00129 fdhD_narQ: formate dehydrogenase family accessory protein FdhD 8 225 9.5E-84 T 01-11-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 AFULGI_00003720 54d3db477aa8957a2c1e7799869ec039 227 PIRSF PIRSF015626 3 221 1.1E-56 T 01-11-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 AFULGI_00003720 54d3db477aa8957a2c1e7799869ec039 227 Pfam PF02634 FdhD/NarQ family 14 217 1.3E-45 T 01-11-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 AFULGI_00003720 54d3db477aa8957a2c1e7799869ec039 227 Gene3D G3DSA:3.10.20.10 14 87 4.0E-11 T 01-11-2018 AFULGI_00003720 54d3db477aa8957a2c1e7799869ec039 227 SUPERFAMILY SSF53927 10 216 5.72E-44 T 01-11-2018 IPR016193 Cytidine deaminase-like GO:0003824 AFULGI_00003720 54d3db477aa8957a2c1e7799869ec039 227 Gene3D G3DSA:3.40.140.10 90 221 3.7E-29 T 01-11-2018 AFULGI_00022300 32e57b1871cee4fa096a392aa8db143c 313 Gene3D G3DSA:1.25.40.10 85 218 1.8E-20 T 01-11-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFULGI_00022300 32e57b1871cee4fa096a392aa8db143c 313 SMART SM00028 141 174 0.25 T 01-11-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFULGI_00022300 32e57b1871cee4fa096a392aa8db143c 313 SMART SM00028 226 259 0.054 T 01-11-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFULGI_00022300 32e57b1871cee4fa096a392aa8db143c 313 SMART SM00028 271 304 0.019 T 01-11-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFULGI_00022300 32e57b1871cee4fa096a392aa8db143c 313 SMART SM00028 181 214 0.041 T 01-11-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFULGI_00022300 32e57b1871cee4fa096a392aa8db143c 313 SMART SM00028 101 134 28.0 T 01-11-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFULGI_00022300 32e57b1871cee4fa096a392aa8db143c 313 SUPERFAMILY SSF48452 105 309 1.58E-25 T 01-11-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFULGI_00022300 32e57b1871cee4fa096a392aa8db143c 313 Gene3D G3DSA:1.25.40.10 219 312 1.1E-14 T 01-11-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFULGI_00022300 32e57b1871cee4fa096a392aa8db143c 313 Pfam PF13424 Tetratricopeptide repeat 225 299 1.7E-12 T 01-11-2018 AFULGI_00022300 32e57b1871cee4fa096a392aa8db143c 313 Pfam PF13424 Tetratricopeptide repeat 141 213 3.0E-13 T 01-11-2018 AFULGI_00026550 00600e873d3c21962d17ac29d1b30e3c 252 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 199 213 - T 01-11-2018 IPR020550 Inositol monophosphatase, conserved site GO:0046854 AFULGI_00026550 00600e873d3c21962d17ac29d1b30e3c 252 Gene3D G3DSA:3.40.190.80 139 252 1.1E-32 T 01-11-2018 AFULGI_00026550 00600e873d3c21962d17ac29d1b30e3c 252 Pfam PF00459 Inositol monophosphatase family 13 250 6.6E-28 T 01-11-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFULGI_00026550 00600e873d3c21962d17ac29d1b30e3c 252 Gene3D G3DSA:3.30.540.10 1 138 1.1E-35 T 01-11-2018 AFULGI_00026550 00600e873d3c21962d17ac29d1b30e3c 252 PRINTS PR00377 Inositol monophosphatase superfamily signature 40 60 1.9E-21 T 01-11-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFULGI_00026550 00600e873d3c21962d17ac29d1b30e3c 252 PRINTS PR00377 Inositol monophosphatase superfamily signature 196 220 1.9E-21 T 01-11-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFULGI_00026550 00600e873d3c21962d17ac29d1b30e3c 252 PRINTS PR00377 Inositol monophosphatase superfamily signature 130 153 1.9E-21 T 01-11-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFULGI_00026550 00600e873d3c21962d17ac29d1b30e3c 252 PRINTS PR00377 Inositol monophosphatase superfamily signature 79 95 1.9E-21 T 01-11-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFULGI_00026550 00600e873d3c21962d17ac29d1b30e3c 252 PRINTS PR00377 Inositol monophosphatase superfamily signature 161 182 1.9E-21 T 01-11-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFULGI_00026550 00600e873d3c21962d17ac29d1b30e3c 252 SUPERFAMILY SSF56655 1 251 4.45E-56 T 01-11-2018 AFULGI_00021980 4657b6c4eb13315d2f2aef19479828a8 673 SUPERFAMILY SSF52210 348 505 2.88E-34 T 01-11-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AFULGI_00021980 4657b6c4eb13315d2f2aef19479828a8 673 Pfam PF13549 ATP-grasp domain 2 205 4.9E-63 T 01-11-2018 AFULGI_00021980 4657b6c4eb13315d2f2aef19479828a8 673 Pfam PF13380 CoA binding domain 225 350 9.7E-25 T 01-11-2018 IPR003781 CoA-binding GO:0048037 AFULGI_00021980 4657b6c4eb13315d2f2aef19479828a8 673 Gene3D G3DSA:3.40.50.720 216 345 1.1E-48 T 01-11-2018 AFULGI_00021980 4657b6c4eb13315d2f2aef19479828a8 673 SUPERFAMILY SSF56059 1 208 1.94E-43 T 01-11-2018 AFULGI_00021980 4657b6c4eb13315d2f2aef19479828a8 673 SUPERFAMILY SSF52210 511 668 1.83E-22 T 01-11-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AFULGI_00021980 4657b6c4eb13315d2f2aef19479828a8 673 SUPERFAMILY SSF51735 215 354 5.03E-40 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily AFULGI_00021980 4657b6c4eb13315d2f2aef19479828a8 673 Gene3D G3DSA:3.40.50.261 346 508 2.1E-47 T 01-11-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AFULGI_00021980 4657b6c4eb13315d2f2aef19479828a8 673 Gene3D G3DSA:3.30.1490.20 21 91 3.8E-72 T 01-11-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 AFULGI_00021980 4657b6c4eb13315d2f2aef19479828a8 673 Gene3D G3DSA:3.30.470.20 3 203 3.8E-72 T 01-11-2018 AFULGI_00021980 4657b6c4eb13315d2f2aef19479828a8 673 Gene3D G3DSA:3.40.50.261 509 672 4.6E-32 T 01-11-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AFULGI_00021980 4657b6c4eb13315d2f2aef19479828a8 673 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 368 505 7.5E-46 T 01-11-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain AFULGI_00021980 4657b6c4eb13315d2f2aef19479828a8 673 SMART SM00881 221 316 6.1E-42 T 01-11-2018 IPR003781 CoA-binding GO:0048037 AFULGI_00018080 b49d62456e2249e7e86dc67ef5671c48 300 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 287 2.1E-51 T 01-11-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFULGI_00018080 b49d62456e2249e7e86dc67ef5671c48 300 Gene3D G3DSA:3.50.50.60 2 292 2.6E-104 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFULGI_00018080 b49d62456e2249e7e86dc67ef5671c48 300 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 2 298 5.1E-117 T 01-11-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 AFULGI_00018080 b49d62456e2249e7e86dc67ef5671c48 300 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 99 117 7.4E-36 T 01-11-2018 AFULGI_00018080 b49d62456e2249e7e86dc67ef5671c48 300 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 224 240 7.4E-36 T 01-11-2018 AFULGI_00018080 b49d62456e2249e7e86dc67ef5671c48 300 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 141 159 7.4E-36 T 01-11-2018 AFULGI_00018080 b49d62456e2249e7e86dc67ef5671c48 300 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 7.4E-36 T 01-11-2018 AFULGI_00018080 b49d62456e2249e7e86dc67ef5671c48 300 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 251 273 7.4E-36 T 01-11-2018 AFULGI_00018080 b49d62456e2249e7e86dc67ef5671c48 300 Gene3D G3DSA:3.50.50.60 111 232 2.6E-104 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFULGI_00018080 b49d62456e2249e7e86dc67ef5671c48 300 SUPERFAMILY SSF51905 1 298 3.58E-54 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFULGI_00018080 b49d62456e2249e7e86dc67ef5671c48 300 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 188 204 4.3E-60 T 01-11-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFULGI_00018080 b49d62456e2249e7e86dc67ef5671c48 300 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 36 51 4.3E-60 T 01-11-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFULGI_00018080 b49d62456e2249e7e86dc67ef5671c48 300 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 100 108 4.3E-60 T 01-11-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFULGI_00018080 b49d62456e2249e7e86dc67ef5671c48 300 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 226 247 4.3E-60 T 01-11-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFULGI_00018080 b49d62456e2249e7e86dc67ef5671c48 300 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 55 65 4.3E-60 T 01-11-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFULGI_00018080 b49d62456e2249e7e86dc67ef5671c48 300 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 3 25 4.3E-60 T 01-11-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFULGI_00018080 b49d62456e2249e7e86dc67ef5671c48 300 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 261 279 4.3E-60 T 01-11-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFULGI_00018080 b49d62456e2249e7e86dc67ef5671c48 300 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 122 134 4.3E-60 T 01-11-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFULGI_00018080 b49d62456e2249e7e86dc67ef5671c48 300 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 137 161 4.3E-60 T 01-11-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFULGI_00025510 83835eea0069218f6fa29b89a21ed746 348 Pfam PF02655 ATP-grasp domain 97 247 1.9E-40 T 01-11-2018 IPR003806 ATP-grasp fold, DUF201-type GO:0005524|GO:0046872 AFULGI_00025510 83835eea0069218f6fa29b89a21ed746 348 PIRSF PIRSF016817 1 348 3.2E-117 T 01-11-2018 IPR016677 Uncharacterised conserved protein UCP016817, ATP-dependent carboligase AFULGI_00025510 83835eea0069218f6fa29b89a21ed746 348 Gene3D G3DSA:3.30.470.20 94 249 3.0E-29 T 01-11-2018 AFULGI_00025510 83835eea0069218f6fa29b89a21ed746 348 Gene3D G3DSA:3.30.1490.350 115 153 3.0E-29 T 01-11-2018 AFULGI_00025510 83835eea0069218f6fa29b89a21ed746 348 SUPERFAMILY SSF56059 97 283 4.77E-24 T 01-11-2018 AFULGI_00024230 187f0bdfb43a76afb5f0dff217c5c1e7 208 SUPERFAMILY SSF56281 11 200 9.21E-28 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFULGI_00024230 187f0bdfb43a76afb5f0dff217c5c1e7 208 Gene3D G3DSA:3.60.15.10 10 206 3.7E-56 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFULGI_00024230 187f0bdfb43a76afb5f0dff217c5c1e7 208 Pfam PF13483 Beta-lactamase superfamily domain 12 180 1.3E-33 T 01-11-2018 AFULGI_00018780 6e91565c4ee4e3714b91ab3f9a303f9a 71 SUPERFAMILY SSF47413 3 64 1.61E-19 T 01-11-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFULGI_00018780 6e91565c4ee4e3714b91ab3f9a303f9a 71 SMART SM00530 4 59 3.4E-17 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFULGI_00018780 6e91565c4ee4e3714b91ab3f9a303f9a 71 Gene3D G3DSA:1.10.260.40 1 65 6.7E-28 T 01-11-2018 AFULGI_00018780 6e91565c4ee4e3714b91ab3f9a303f9a 71 Pfam PF01381 Helix-turn-helix 5 58 8.2E-17 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFULGI_00021360 976aa1a5579367a7f943ddbce7fbb69f 94 Hamap MF_01471 CRISPR-associated endoribonuclease Cas2 [cas2]. 1 86 17.422 T 01-11-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 AFULGI_00021360 976aa1a5579367a7f943ddbce7fbb69f 94 SUPERFAMILY SSF143430 1 79 9.68E-21 T 01-11-2018 AFULGI_00021360 976aa1a5579367a7f943ddbce7fbb69f 94 TIGRFAM TIGR01573 cas2: CRISPR-associated endonuclease Cas2 1 93 2.5E-28 T 01-11-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 AFULGI_00021360 976aa1a5579367a7f943ddbce7fbb69f 94 Gene3D G3DSA:3.30.70.240 2 67 2.4E-23 T 01-11-2018 AFULGI_00021360 976aa1a5579367a7f943ddbce7fbb69f 94 Pfam PF09827 CRISPR associated protein Cas2 1 73 1.6E-20 T 01-11-2018 IPR019199 Virulence-associated protein D / CRISPR associated protein Cas2 AFULGI_00019830 57d23797ebeea791cb0beb07db479a64 340 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 140 147 - T 01-11-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFULGI_00019830 57d23797ebeea791cb0beb07db479a64 340 Gene3D G3DSA:3.40.50.720 5 335 3.5E-141 T 01-11-2018 AFULGI_00019830 57d23797ebeea791cb0beb07db479a64 340 SUPERFAMILY SSF55347 142 302 5.89E-51 T 01-11-2018 AFULGI_00019830 57d23797ebeea791cb0beb07db479a64 340 SUPERFAMILY SSF51735 4 159 2.14E-47 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily AFULGI_00019830 57d23797ebeea791cb0beb07db479a64 340 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 4 109 3.5E-10 T 01-11-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AFULGI_00019830 57d23797ebeea791cb0beb07db479a64 340 TIGRFAM TIGR01546 GAPDH-II_archae: glyceraldehyde-3-phosphate dehydrogenase, type II 6 336 1.5E-144 T 01-11-2018 IPR006436 Glyceraldehyde-3-phosphate dehydrogenase, type II GO:0005737|GO:0006096|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.59|KEGG: 00710+1.2.1.59 AFULGI_00019830 57d23797ebeea791cb0beb07db479a64 340 Hamap MF_00559 Glyceraldehyde-3-phosphate dehydrogenase [gap]. 1 340 183.849 T 01-11-2018 IPR006436 Glyceraldehyde-3-phosphate dehydrogenase, type II GO:0005737|GO:0006096|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.59|KEGG: 00710+1.2.1.59 AFULGI_00019830 57d23797ebeea791cb0beb07db479a64 340 SMART SM00846 4 142 1.2E-21 T 01-11-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFULGI_00019830 57d23797ebeea791cb0beb07db479a64 340 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 147 300 1.9E-30 T 01-11-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFULGI_00019830 57d23797ebeea791cb0beb07db479a64 340 PIRSF PIRSF000149 2 322 9.7E-92 T 01-11-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFULGI_00019830 57d23797ebeea791cb0beb07db479a64 340 Gene3D G3DSA:3.30.360.10 142 307 3.5E-141 T 01-11-2018 AFULGI_00012180 a8c38a1caf31c32f54d792023802e05c 155 SMART SM00344 2 111 1.6E-31 T 01-11-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 AFULGI_00012180 a8c38a1caf31c32f54d792023802e05c 155 SUPERFAMILY SSF46785 3 52 5.06E-10 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00012180 a8c38a1caf31c32f54d792023802e05c 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 27 46 6.5E-5 T 01-11-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFULGI_00012180 a8c38a1caf31c32f54d792023802e05c 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 16 27 6.5E-5 T 01-11-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFULGI_00012180 a8c38a1caf31c32f54d792023802e05c 155 Pfam PF12840 Helix-turn-helix domain 6 51 2.5E-7 T 01-11-2018 AFULGI_00012180 a8c38a1caf31c32f54d792023802e05c 155 Gene3D G3DSA:1.10.10.10 4 56 4.3E-8 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00012180 a8c38a1caf31c32f54d792023802e05c 155 Gene3D G3DSA:3.30.70.920 57 154 3.6E-6 T 01-11-2018 AFULGI_00012330 258eeb5b83e21e418b154ae25127f091 456 SUPERFAMILY SSF53474 21 424 4.33E-33 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold AFULGI_00012330 258eeb5b83e21e418b154ae25127f091 456 Pfam PF12146 Serine aminopeptidase, S33 106 191 2.1E-6 T 01-11-2018 IPR022742 Serine aminopeptidase, S33 AFULGI_00019710 781cf81c973d4eba30288e9ff6f66e6a 552 Gene3D G3DSA:3.40.50.1220 184 348 9.6E-68 T 01-11-2018 AFULGI_00019710 781cf81c973d4eba30288e9ff6f66e6a 552 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 379 527 1.4E-51 T 01-11-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 AFULGI_00019710 781cf81c973d4eba30288e9ff6f66e6a 552 SUPERFAMILY SSF52518 356 549 2.64E-67 T 01-11-2018 IPR029061 Thiamin diphosphate-binding fold AFULGI_00019710 781cf81c973d4eba30288e9ff6f66e6a 552 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 190 325 3.1E-53 T 01-11-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 AFULGI_00019710 781cf81c973d4eba30288e9ff6f66e6a 552 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 1 551 2.5E-283 T 01-11-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 AFULGI_00019710 781cf81c973d4eba30288e9ff6f66e6a 552 Gene3D G3DSA:3.40.50.970 349 552 1.3E-67 T 01-11-2018 AFULGI_00019710 781cf81c973d4eba30288e9ff6f66e6a 552 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 415 434 - T 01-11-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 AFULGI_00019710 781cf81c973d4eba30288e9ff6f66e6a 552 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 1 167 4.4E-58 T 01-11-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 AFULGI_00019710 781cf81c973d4eba30288e9ff6f66e6a 552 Gene3D G3DSA:3.40.50.970 1 180 4.2E-72 T 01-11-2018 AFULGI_00019710 781cf81c973d4eba30288e9ff6f66e6a 552 SUPERFAMILY SSF52518 1 179 1.12E-62 T 01-11-2018 IPR029061 Thiamin diphosphate-binding fold AFULGI_00019710 781cf81c973d4eba30288e9ff6f66e6a 552 SUPERFAMILY SSF52467 183 350 2.52E-62 T 01-11-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily AFULGI_00020100 d626418a6d200b836b99cf17ebf21ce0 278 Gene3D G3DSA:3.40.1700.10 193 275 9.8E-13 T 01-11-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily AFULGI_00020100 d626418a6d200b836b99cf17ebf21ce0 278 PIRSF PIRSF019073 2 278 5.1E-110 T 01-11-2018 IPR014499 Diadenylate cyclase, DacZ-type AFULGI_00020100 d626418a6d200b836b99cf17ebf21ce0 278 SUPERFAMILY SSF143597 67 272 7.85E-31 T 01-11-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily AFULGI_00020100 d626418a6d200b836b99cf17ebf21ce0 278 Hamap MF_00840 Diadenylate cyclase [dacZ]. 4 278 34.074 T 01-11-2018 IPR014499 Diadenylate cyclase, DacZ-type AFULGI_00020100 d626418a6d200b836b99cf17ebf21ce0 278 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 141 267 6.3E-21 T 01-11-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal AFULGI_00022470 b31718ab1034c661ecc172ed45ae6a3d 332 SUPERFAMILY SSF51735 3 184 2.25E-71 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily AFULGI_00022470 b31718ab1034c661ecc172ed45ae6a3d 332 Hamap MF_00435 Ketol-acid reductoisomerase (NADP(+)) [ilvC]. 2 330 43.184 T 01-11-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 AFULGI_00022470 b31718ab1034c661ecc172ed45ae6a3d 332 Gene3D G3DSA:1.10.3730.40 184 332 4.2E-70 T 01-11-2018 AFULGI_00022470 b31718ab1034c661ecc172ed45ae6a3d 332 SUPERFAMILY SSF48179 185 330 2.04E-67 T 01-11-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AFULGI_00022470 b31718ab1034c661ecc172ed45ae6a3d 332 Gene3D G3DSA:3.40.50.720 2 183 6.5E-77 T 01-11-2018 AFULGI_00022470 b31718ab1034c661ecc172ed45ae6a3d 332 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 15 330 5.3E-152 T 01-11-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 AFULGI_00022470 b31718ab1034c661ecc172ed45ae6a3d 332 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 185 328 2.1E-63 T 01-11-2018 IPR000506 Ketol-acid reductoisomerase, C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 AFULGI_00022470 b31718ab1034c661ecc172ed45ae6a3d 332 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 15 179 1.5E-75 T 01-11-2018 IPR013116 Ketol-acid reductoisomerase, N-terminal KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 AFULGI_00022470 b31718ab1034c661ecc172ed45ae6a3d 332 PIRSF PIRSF000116 4 207 9.0E-41 T 01-11-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 AFULGI_00022470 b31718ab1034c661ecc172ed45ae6a3d 332 PIRSF PIRSF000116 204 331 5.3E-17 T 01-11-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 AFULGI_00006460 092816c991bde60be04be0677f2626b9 392 Gene3D G3DSA:3.40.50.1440 28 332 5.0E-96 T 01-11-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 AFULGI_00006460 092816c991bde60be04be0677f2626b9 392 ProSitePatterns PS01135 FtsZ protein signature 2. 115 136 - T 01-11-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 AFULGI_00006460 092816c991bde60be04be0677f2626b9 392 SUPERFAMILY SSF55307 223 338 1.28E-33 T 01-11-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 AFULGI_00006460 092816c991bde60be04be0677f2626b9 392 PRINTS PR00423 Cell division protein FtsZ signature 228 249 2.8E-31 T 01-11-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 AFULGI_00006460 092816c991bde60be04be0677f2626b9 392 PRINTS PR00423 Cell division protein FtsZ signature 116 136 2.8E-31 T 01-11-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 AFULGI_00006460 092816c991bde60be04be0677f2626b9 392 PRINTS PR00423 Cell division protein FtsZ signature 144 165 2.8E-31 T 01-11-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 AFULGI_00006460 092816c991bde60be04be0677f2626b9 392 PRINTS PR00423 Cell division protein FtsZ signature 205 227 2.8E-31 T 01-11-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 AFULGI_00006460 092816c991bde60be04be0677f2626b9 392 SUPERFAMILY SSF52490 30 224 9.68E-57 T 01-11-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 AFULGI_00006460 092816c991bde60be04be0677f2626b9 392 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 14 357 3.5E-136 T 01-11-2018 IPR000158 Cell division protein FtsZ GO:0005525 AFULGI_00006460 092816c991bde60be04be0677f2626b9 392 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 31 189 3.1E-36 T 01-11-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 AFULGI_00006460 092816c991bde60be04be0677f2626b9 392 Pfam PF12327 FtsZ family, C-terminal domain 238 332 1.8E-35 T 01-11-2018 IPR024757 Cell division protein FtsZ, C-terminal AFULGI_00006460 092816c991bde60be04be0677f2626b9 392 ProSitePatterns PS01134 FtsZ protein signature 1. 62 96 - T 01-11-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 AFULGI_00006460 092816c991bde60be04be0677f2626b9 392 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 27 362 31.568 T 01-11-2018 IPR000158 Cell division protein FtsZ GO:0005525 AFULGI_00006460 092816c991bde60be04be0677f2626b9 392 SMART SM00864 31 221 3.6E-82 T 01-11-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 AFULGI_00006460 092816c991bde60be04be0677f2626b9 392 SMART SM00865 223 340 1.9E-38 T 01-11-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-380320 AFULGI_00019130 e2749140456ae9e8223a61171372f74f 752 TIGRFAM TIGR02504 NrdJ_Z: ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent 8 560 9.5E-238 T 01-11-2018 IPR013344 Ribonucleotide reductase, adenosylcobalamin-dependent GO:0000166|GO:0004748|GO:0031419|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 AFULGI_00019130 e2749140456ae9e8223a61171372f74f 752 PRINTS PR01183 Ribonucleotide reductase large chain signature 402 429 1.8E-33 T 01-11-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AFULGI_00019130 e2749140456ae9e8223a61171372f74f 752 PRINTS PR01183 Ribonucleotide reductase large chain signature 296 319 1.8E-33 T 01-11-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AFULGI_00019130 e2749140456ae9e8223a61171372f74f 752 PRINTS PR01183 Ribonucleotide reductase large chain signature 159 178 1.8E-33 T 01-11-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AFULGI_00019130 e2749140456ae9e8223a61171372f74f 752 PRINTS PR01183 Ribonucleotide reductase large chain signature 362 385 1.8E-33 T 01-11-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AFULGI_00019130 e2749140456ae9e8223a61171372f74f 752 PRINTS PR01183 Ribonucleotide reductase large chain signature 334 356 1.8E-33 T 01-11-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AFULGI_00019130 e2749140456ae9e8223a61171372f74f 752 Pfam PF02867 Ribonucleotide reductase, barrel domain 84 550 1.2E-172 T 01-11-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AFULGI_00019130 e2749140456ae9e8223a61171372f74f 752 Gene3D G3DSA:3.20.70.20 1 565 6.8E-254 T 01-11-2018 AFULGI_00019130 e2749140456ae9e8223a61171372f74f 752 SUPERFAMILY SSF51998 83 561 7.32E-166 T 01-11-2018 AFULGI_00019130 e2749140456ae9e8223a61171372f74f 752 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 3 80 1.4E-28 T 01-11-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AFULGI_00019130 e2749140456ae9e8223a61171372f74f 752 SUPERFAMILY SSF48168 7 82 7.59E-17 T 01-11-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AFULGI_00019130 e2749140456ae9e8223a61171372f74f 752 Pfam PF12637 TSCPD domain 597 685 6.7E-8 T 01-11-2018 IPR024434 TSCPD domain AFULGI_00012690 5463f25df194d9eb5cc40e6bf4ba0ca6 370 SMART SM00382 31 203 0.39 T 01-11-2018 IPR003593 AAA+ ATPase domain AFULGI_00012690 5463f25df194d9eb5cc40e6bf4ba0ca6 370 SMART SM00382 231 370 3.2E-9 T 01-11-2018 IPR003593 AAA+ ATPase domain AFULGI_00012690 5463f25df194d9eb5cc40e6bf4ba0ca6 370 Pfam PF00005 ABC transporter 228 330 2.1E-10 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFULGI_00012690 5463f25df194d9eb5cc40e6bf4ba0ca6 370 SUPERFAMILY SSF52540 228 369 2.37E-26 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00012690 5463f25df194d9eb5cc40e6bf4ba0ca6 370 Gene3D G3DSA:3.40.50.300 222 370 1.9E-27 T 01-11-2018 AFULGI_00012690 5463f25df194d9eb5cc40e6bf4ba0ca6 370 Gene3D G3DSA:3.40.50.300 7 221 6.2E-31 T 01-11-2018 AFULGI_00012690 5463f25df194d9eb5cc40e6bf4ba0ca6 370 Pfam PF00005 ABC transporter 37 166 1.4E-16 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFULGI_00012690 5463f25df194d9eb5cc40e6bf4ba0ca6 370 SUPERFAMILY SSF52540 25 204 9.12E-30 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00004120 cda1c6507176b886090cde86ddec615c 169 Pfam PF04407 Protein of unknown function (DUF531) 1 159 1.3E-71 T 01-11-2018 IPR007501 Protein of unknown function DUF531 AFULGI_00004120 cda1c6507176b886090cde86ddec615c 169 PIRSF PIRSF006006 1 169 6.6E-80 T 01-11-2018 IPR007501 Protein of unknown function DUF531 AFULGI_00019330 1b31fb89d22490fe7f1a860838ae87c3 469 SUPERFAMILY SSF102114 181 395 1.16E-37 T 01-11-2018 AFULGI_00019330 1b31fb89d22490fe7f1a860838ae87c3 469 SMART SM00729 181 385 3.5E-37 T 01-11-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 AFULGI_00019330 1b31fb89d22490fe7f1a860838ae87c3 469 Gene3D G3DSA:3.80.30.20 181 390 6.9E-15 T 01-11-2018 IPR023404 Radical SAM, alpha/beta horseshoe AFULGI_00019330 1b31fb89d22490fe7f1a860838ae87c3 469 Pfam PF04055 Radical SAM superfamily 186 335 1.6E-17 T 01-11-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFULGI_00002410 bebbf9cc83aeab95e4d2509be092d1cb 439 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 377 392 2.9E-22 T 01-11-2018 AFULGI_00002410 bebbf9cc83aeab95e4d2509be092d1cb 439 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 2 24 2.9E-22 T 01-11-2018 AFULGI_00002410 bebbf9cc83aeab95e4d2509be092d1cb 439 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 146 171 2.9E-22 T 01-11-2018 AFULGI_00002410 bebbf9cc83aeab95e4d2509be092d1cb 439 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 269 276 2.9E-22 T 01-11-2018 AFULGI_00002410 bebbf9cc83aeab95e4d2509be092d1cb 439 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 229 243 2.9E-22 T 01-11-2018 AFULGI_00002410 bebbf9cc83aeab95e4d2509be092d1cb 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 228 244 1.3E-26 T 01-11-2018 AFULGI_00002410 bebbf9cc83aeab95e4d2509be092d1cb 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 254 276 1.3E-26 T 01-11-2018 AFULGI_00002410 bebbf9cc83aeab95e4d2509be092d1cb 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 146 164 1.3E-26 T 01-11-2018 AFULGI_00002410 bebbf9cc83aeab95e4d2509be092d1cb 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 1.3E-26 T 01-11-2018 AFULGI_00002410 bebbf9cc83aeab95e4d2509be092d1cb 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 101 119 1.3E-26 T 01-11-2018 AFULGI_00002410 bebbf9cc83aeab95e4d2509be092d1cb 439 Gene3D G3DSA:3.50.50.60 2 332 3.1E-130 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFULGI_00002410 bebbf9cc83aeab95e4d2509be092d1cb 439 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 299 9.3E-58 T 01-11-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFULGI_00002410 bebbf9cc83aeab95e4d2509be092d1cb 439 SUPERFAMILY SSF55424 321 435 6.87E-22 T 01-11-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 AFULGI_00002410 bebbf9cc83aeab95e4d2509be092d1cb 439 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 324 421 7.5E-15 T 01-11-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 AFULGI_00002410 bebbf9cc83aeab95e4d2509be092d1cb 439 SUPERFAMILY SSF51905 2 308 4.86E-44 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFULGI_00002410 bebbf9cc83aeab95e4d2509be092d1cb 439 Gene3D G3DSA:3.50.50.60 110 429 3.1E-130 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFULGI_00017200 5959dd0f075b3ee44e4f5745531d5add 489 Gene3D G3DSA:2.60.40.10 203 307 1.0E-5 T 01-11-2018 IPR013783 Immunoglobulin-like fold AFULGI_00017200 5959dd0f075b3ee44e4f5745531d5add 489 Pfam PF08626 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit 35 105 3.5E-5 T 01-11-2018 IPR013935 TRAPP II complex, Trs120 Reactome: R-HSA-204005|Reactome: R-HSA-8876198 AFULGI_00017200 5959dd0f075b3ee44e4f5745531d5add 489 SUPERFAMILY SSF49309 36 108 3.92E-6 T 01-11-2018 IPR036238 Transglutaminase, C-terminal domain superfamily GO:0003810|GO:0018149 AFULGI_00025660 b0106eacb388a0511f182010e923c2db 254 Hamap MF_02040 Iron-sulfur cluster carrier protein. 12 249 34.34 T 01-11-2018 IPR019591 Mrp/NBP35 ATP-binding protein AFULGI_00025660 b0106eacb388a0511f182010e923c2db 254 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 20 240 6.3E-90 T 01-11-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 AFULGI_00025660 b0106eacb388a0511f182010e923c2db 254 Gene3D G3DSA:3.40.50.300 1 252 3.2E-88 T 01-11-2018 AFULGI_00025660 b0106eacb388a0511f182010e923c2db 254 SUPERFAMILY SSF52540 8 240 4.36E-55 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00025660 b0106eacb388a0511f182010e923c2db 254 ProSitePatterns PS01215 Mrp family signature. 126 142 - T 01-11-2018 IPR000808 Mrp, conserved site GO:0005524 AFULGI_00018500 c0bd1ea3f15c68ee5aa93ea4b4255433 384 SUPERFAMILY SSF53686 3 380 2.1E-148 T 01-11-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme AFULGI_00018500 c0bd1ea3f15c68ee5aa93ea4b4255433 384 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 74 88 - T 01-11-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 AFULGI_00018500 c0bd1ea3f15c68ee5aa93ea4b4255433 384 Gene3D G3DSA:3.40.50.1100 48 376 3.0E-188 T 01-11-2018 AFULGI_00018500 c0bd1ea3f15c68ee5aa93ea4b4255433 384 PIRSF PIRSF001413 2 384 1.0E-165 T 01-11-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 AFULGI_00018500 c0bd1ea3f15c68ee5aa93ea4b4255433 384 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 46 370 3.6E-49 T 01-11-2018 IPR001926 Pyridoxal-phosphate dependent enzyme AFULGI_00018500 c0bd1ea3f15c68ee5aa93ea4b4255433 384 Gene3D G3DSA:3.40.50.1100 4 199 3.0E-188 T 01-11-2018 AFULGI_00018500 c0bd1ea3f15c68ee5aa93ea4b4255433 384 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 1 383 52.832 T 01-11-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 AFULGI_00018500 c0bd1ea3f15c68ee5aa93ea4b4255433 384 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 2 381 4.2E-194 T 01-11-2018 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 AFULGI_00011790 e351dde81a1123949c1379a1aa6ee0f1 86 Gene3D G3DSA:3.30.2310.20 6 79 8.0E-7 T 01-11-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily AFULGI_00011790 e351dde81a1123949c1379a1aa6ee0f1 86 SUPERFAMILY SSF143011 8 70 2.04E-8 T 01-11-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily AFULGI_00004430 629100e154055165852092a753e46e88 165 SUPERFAMILY SSF46785 5 59 6.56E-9 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00004430 629100e154055165852092a753e46e88 165 ProSitePatterns PS00519 AsnC-type HTH domain signature. 22 48 - T 01-11-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site AFULGI_00004430 629100e154055165852092a753e46e88 165 Gene3D G3DSA:3.30.70.920 60 161 1.1E-7 T 01-11-2018 AFULGI_00004430 629100e154055165852092a753e46e88 165 SMART SM00344 6 117 1.3E-33 T 01-11-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 AFULGI_00004430 629100e154055165852092a753e46e88 165 Pfam PF13412 Winged helix-turn-helix DNA-binding 6 50 4.0E-9 T 01-11-2018 AFULGI_00004430 629100e154055165852092a753e46e88 165 Gene3D G3DSA:1.10.10.10 6 52 3.1E-7 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00026930 e62f92f86aa8bef8846619430dcda9f3 262 Pfam PF01261 Xylose isomerase-like TIM barrel 21 209 6.0E-14 T 01-11-2018 IPR013022 Xylose isomerase-like, TIM barrel domain AFULGI_00026930 e62f92f86aa8bef8846619430dcda9f3 262 Gene3D G3DSA:3.20.20.150 1 258 1.8E-35 T 01-11-2018 AFULGI_00026930 e62f92f86aa8bef8846619430dcda9f3 262 SUPERFAMILY SSF51658 1 236 1.37E-32 T 01-11-2018 IPR036237 Xylose isomerase-like superfamily AFULGI_00025350 6aa6f9252ea3987a3651d1fe83150c00 444 Pfam PF00206 Lyase 12 293 4.8E-56 T 01-11-2018 IPR022761 Fumarate lyase, N-terminal AFULGI_00025350 6aa6f9252ea3987a3651d1fe83150c00 444 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 6 436 2.4E-181 T 01-11-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 AFULGI_00025350 6aa6f9252ea3987a3651d1fe83150c00 444 PRINTS PR00145 Argininosuccinate lyase family signature 91 113 3.8E-8 T 01-11-2018 AFULGI_00025350 6aa6f9252ea3987a3651d1fe83150c00 444 PRINTS PR00145 Argininosuccinate lyase family signature 132 152 3.8E-8 T 01-11-2018 AFULGI_00025350 6aa6f9252ea3987a3651d1fe83150c00 444 PRINTS PR00145 Argininosuccinate lyase family signature 223 247 3.8E-8 T 01-11-2018 AFULGI_00025350 6aa6f9252ea3987a3651d1fe83150c00 444 PRINTS PR00145 Argininosuccinate lyase family signature 268 284 3.8E-8 T 01-11-2018 AFULGI_00025350 6aa6f9252ea3987a3651d1fe83150c00 444 Gene3D G3DSA:1.20.200.10 97 355 1.1E-91 T 01-11-2018 AFULGI_00025350 6aa6f9252ea3987a3651d1fe83150c00 444 ProSitePatterns PS00163 Fumarate lyases signature. 268 277 - T 01-11-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 AFULGI_00025350 6aa6f9252ea3987a3651d1fe83150c00 444 SMART SM00998 356 436 7.1E-34 T 01-11-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 AFULGI_00025350 6aa6f9252ea3987a3651d1fe83150c00 444 PRINTS PR00149 Fumarate lyase superfamily signature 223 250 2.9E-26 T 01-11-2018 IPR000362 Fumarate lyase family AFULGI_00025350 6aa6f9252ea3987a3651d1fe83150c00 444 PRINTS PR00149 Fumarate lyase superfamily signature 92 110 2.9E-26 T 01-11-2018 IPR000362 Fumarate lyase family AFULGI_00025350 6aa6f9252ea3987a3651d1fe83150c00 444 PRINTS PR00149 Fumarate lyase superfamily signature 137 155 2.9E-26 T 01-11-2018 IPR000362 Fumarate lyase family AFULGI_00025350 6aa6f9252ea3987a3651d1fe83150c00 444 PRINTS PR00149 Fumarate lyase superfamily signature 268 284 2.9E-26 T 01-11-2018 IPR000362 Fumarate lyase family AFULGI_00025350 6aa6f9252ea3987a3651d1fe83150c00 444 Gene3D G3DSA:1.10.275.10 1 96 3.5E-35 T 01-11-2018 IPR024083 Fumarase/histidase, N-terminal AFULGI_00025350 6aa6f9252ea3987a3651d1fe83150c00 444 Gene3D G3DSA:1.10.40.30 356 436 2.9E-25 T 01-11-2018 AFULGI_00025350 6aa6f9252ea3987a3651d1fe83150c00 444 SUPERFAMILY SSF48557 4 443 3.93E-128 T 01-11-2018 IPR008948 L-Aspartase-like GO:0003824 AFULGI_00025350 6aa6f9252ea3987a3651d1fe83150c00 444 Pfam PF10397 Adenylosuccinate lyase C-terminus 357 435 1.8E-22 T 01-11-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 AFULGI_00013190 bd1f5e450467dca7e54e86419f3d7951 407 SUPERFAMILY SSF55315 267 403 4.45E-40 T 01-11-2018 IPR029064 50S ribosomal protein L30e-like AFULGI_00013190 bd1f5e450467dca7e54e86419f3d7951 407 SUPERFAMILY SSF55481 5 132 5.75E-48 T 01-11-2018 IPR024049 Peptide Chain Release Factor eRF1/aRF1, N-terminal Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00013190 bd1f5e450467dca7e54e86419f3d7951 407 Hamap MF_00424 Peptide chain release factor subunit 1 [prf1]. 16 404 45.711 T 01-11-2018 IPR020918 Peptide chain release factor aRF1 GO:0003747|GO:0005737|GO:0006415 AFULGI_00013190 bd1f5e450467dca7e54e86419f3d7951 407 Pfam PF03465 eRF1 domain 3 270 402 4.0E-36 T 01-11-2018 IPR005142 eRF1 domain 3 AFULGI_00013190 bd1f5e450467dca7e54e86419f3d7951 407 SMART SM01194 1 132 4.0E-45 T 01-11-2018 IPR005140 eRF1 domain 1/Pelota-like AFULGI_00013190 bd1f5e450467dca7e54e86419f3d7951 407 TIGRFAM TIGR03676 aRF1/eRF1: peptide chain release factor 1, archaeal and eukaryotic forms 6 402 6.5E-183 T 01-11-2018 IPR004403 Peptide chain release factor eRF1/aRF1 GO:0003747|GO:0005737|GO:0006415 Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00013190 bd1f5e450467dca7e54e86419f3d7951 407 Pfam PF03463 eRF1 domain 1 15 130 5.1E-14 T 01-11-2018 IPR005140 eRF1 domain 1/Pelota-like AFULGI_00013190 bd1f5e450467dca7e54e86419f3d7951 407 Gene3D G3DSA:3.30.960.10 1 133 2.0E-48 T 01-11-2018 IPR024049 Peptide Chain Release Factor eRF1/aRF1, N-terminal Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00013190 bd1f5e450467dca7e54e86419f3d7951 407 SUPERFAMILY SSF53137 135 265 1.53E-44 T 01-11-2018 AFULGI_00013190 bd1f5e450467dca7e54e86419f3d7951 407 Gene3D G3DSA:3.30.420.60 134 266 2.4E-50 T 01-11-2018 AFULGI_00013190 bd1f5e450467dca7e54e86419f3d7951 407 Gene3D G3DSA:3.30.1330.30 268 406 2.0E-43 T 01-11-2018 IPR029064 50S ribosomal protein L30e-like AFULGI_00013190 bd1f5e450467dca7e54e86419f3d7951 407 Pfam PF03464 eRF1 domain 2 137 267 1.6E-47 T 01-11-2018 IPR005141 eRF1 domain 2 AFULGI_00008450 3d5f9b3ad28bf8e10f7130c47a87428c 119 TIGRFAM TIGR03677 eL8_ribo: ribosomal protein eL8 2 118 2.1E-57 T 01-11-2018 IPR022481 Ribosomal protein L7Ae, archaea GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFULGI_00008450 3d5f9b3ad28bf8e10f7130c47a87428c 119 ProSitePatterns PS01082 Ribosomal protein L7Ae signature. 66 83 - T 01-11-2018 IPR004037 Ribosomal protein L7Ae conserved site GO:0042254|GO:1990904 Reactome: R-HSA-6791226 AFULGI_00008450 3d5f9b3ad28bf8e10f7130c47a87428c 119 SUPERFAMILY SSF55315 1 116 6.77E-40 T 01-11-2018 IPR029064 50S ribosomal protein L30e-like AFULGI_00008450 3d5f9b3ad28bf8e10f7130c47a87428c 119 Gene3D G3DSA:3.30.1330.30 1 119 7.8E-43 T 01-11-2018 IPR029064 50S ribosomal protein L30e-like AFULGI_00008450 3d5f9b3ad28bf8e10f7130c47a87428c 119 PRINTS PR00884 Ribosomal protein HS6 signature 36 46 8.6E-30 T 01-11-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFULGI_00008450 3d5f9b3ad28bf8e10f7130c47a87428c 119 PRINTS PR00884 Ribosomal protein HS6 signature 46 57 8.6E-30 T 01-11-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFULGI_00008450 3d5f9b3ad28bf8e10f7130c47a87428c 119 PRINTS PR00884 Ribosomal protein HS6 signature 2 13 8.6E-30 T 01-11-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFULGI_00008450 3d5f9b3ad28bf8e10f7130c47a87428c 119 PRINTS PR00884 Ribosomal protein HS6 signature 87 103 8.6E-30 T 01-11-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFULGI_00008450 3d5f9b3ad28bf8e10f7130c47a87428c 119 PRINTS PR00884 Ribosomal protein HS6 signature 73 83 8.6E-30 T 01-11-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFULGI_00008450 3d5f9b3ad28bf8e10f7130c47a87428c 119 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 16 104 9.9E-31 T 01-11-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 AFULGI_00008450 3d5f9b3ad28bf8e10f7130c47a87428c 119 Hamap MF_00326 50S ribosomal protein L7Ae [rpl7ae]. 1 118 32.443 T 01-11-2018 IPR022481 Ribosomal protein L7Ae, archaea GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFULGI_00008450 3d5f9b3ad28bf8e10f7130c47a87428c 119 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 28 42 2.2E-23 T 01-11-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family AFULGI_00008450 3d5f9b3ad28bf8e10f7130c47a87428c 119 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 47 60 2.2E-23 T 01-11-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family AFULGI_00008450 3d5f9b3ad28bf8e10f7130c47a87428c 119 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 73 87 2.2E-23 T 01-11-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family AFULGI_00008450 3d5f9b3ad28bf8e10f7130c47a87428c 119 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 63 73 2.2E-23 T 01-11-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family AFULGI_00003460 bc200e527c60f0514f6c90faccce8178 319 TIGRFAM TIGR00816 tdt: C4-dicarboxylate transporter/malic acid transport protein 6 318 1.6E-109 T 01-11-2018 IPR011552 Tellurite resistance protein TehA/malic acid transport protein GO:0016021 AFULGI_00003460 bc200e527c60f0514f6c90faccce8178 319 Gene3D G3DSA:1.50.10.150 2 319 1.9E-37 T 01-11-2018 IPR038665 Voltage-dependent anion channel superfamily AFULGI_00003460 bc200e527c60f0514f6c90faccce8178 319 Pfam PF03595 Voltage-dependent anion channel 6 312 9.4E-54 T 01-11-2018 IPR004695 Voltage-dependent anion channel GO:0016021|GO:0055085 AFULGI_00002770 bcba58ed9a6a77d413ae06c5f6c48864 395 Pfam PF00108 Thiolase, N-terminal domain 7 224 3.7E-22 T 01-11-2018 IPR020616 Thiolase, N-terminal GO:0016747 AFULGI_00002770 bcba58ed9a6a77d413ae06c5f6c48864 395 Gene3D G3DSA:3.40.47.10 4 393 2.0E-114 T 01-11-2018 IPR016039 Thiolase-like GO:0003824 AFULGI_00002770 bcba58ed9a6a77d413ae06c5f6c48864 395 PIRSF PIRSF000429 1 390 3.3E-59 T 01-11-2018 IPR002155 Thiolase GO:0016747 AFULGI_00002770 bcba58ed9a6a77d413ae06c5f6c48864 395 SUPERFAMILY SSF53901 5 231 1.47E-42 T 01-11-2018 IPR016039 Thiolase-like GO:0003824 AFULGI_00002770 bcba58ed9a6a77d413ae06c5f6c48864 395 Pfam PF02803 Thiolase, C-terminal domain 260 359 7.9E-6 T 01-11-2018 IPR020617 Thiolase, C-terminal GO:0016747 AFULGI_00002770 bcba58ed9a6a77d413ae06c5f6c48864 395 SUPERFAMILY SSF53901 234 389 1.38E-24 T 01-11-2018 IPR016039 Thiolase-like GO:0003824 AFULGI_00010240 2432a97f8bb6c87aba4503e909004da2 171 Pfam PF01842 ACT domain 7 72 2.6E-8 T 01-11-2018 IPR002912 ACT domain AFULGI_00010240 2432a97f8bb6c87aba4503e909004da2 171 Gene3D G3DSA:3.30.70.260 5 81 2.4E-5 T 01-11-2018 AFULGI_00010240 2432a97f8bb6c87aba4503e909004da2 171 SUPERFAMILY SSF55021 7 77 1.34E-8 T 01-11-2018 AFULGI_00026650 190fbff9612146fe9ff09f520fe4f5a7 517 SMART SM00729 70 329 5.0E-53 T 01-11-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 AFULGI_00026650 190fbff9612146fe9ff09f520fe4f5a7 517 Pfam PF04055 Radical SAM superfamily 77 273 9.7E-23 T 01-11-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFULGI_00026650 190fbff9612146fe9ff09f520fe4f5a7 517 SUPERFAMILY SSF55729 390 513 4.33E-9 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase AFULGI_00026650 190fbff9612146fe9ff09f520fe4f5a7 517 TIGRFAM TIGR01211 ELP3: radical SAM enzyme/protein acetyltransferase, ELP3 family 5 517 9.3E-255 T 01-11-2018 IPR034687 Elongator complex protein 3-like Reactome: R-HSA-3214847 AFULGI_00026650 190fbff9612146fe9ff09f520fe4f5a7 517 Pfam PF16199 Radical_SAM C-terminal domain 290 370 3.1E-25 T 01-11-2018 IPR032432 Radical SAM, C-terminal extension Reactome: R-HSA-3214847 AFULGI_00026650 190fbff9612146fe9ff09f520fe4f5a7 517 PIRSF PIRSF005669 2 517 8.5E-233 T 01-11-2018 IPR034687 Elongator complex protein 3-like Reactome: R-HSA-3214847 AFULGI_00026650 190fbff9612146fe9ff09f520fe4f5a7 517 Pfam PF00583 Acetyltransferase (GNAT) family 400 506 4.0E-7 T 01-11-2018 IPR000182 GNAT domain AFULGI_00026650 190fbff9612146fe9ff09f520fe4f5a7 517 Gene3D G3DSA:3.40.630.30 366 516 2.3E-9 T 01-11-2018 AFULGI_00026650 190fbff9612146fe9ff09f520fe4f5a7 517 Gene3D G3DSA:3.80.30.20 140 345 7.2E-16 T 01-11-2018 IPR023404 Radical SAM, alpha/beta horseshoe AFULGI_00026650 190fbff9612146fe9ff09f520fe4f5a7 517 SUPERFAMILY SSF102114 122 336 7.98E-35 T 01-11-2018 AFULGI_00006090 4a3cdbbe109707aaaded3125a1a12e2f 335 SUPERFAMILY SSF88723 107 253 5.89E-5 T 01-11-2018 IPR029060 PIN-like domain superfamily AFULGI_00006090 4a3cdbbe109707aaaded3125a1a12e2f 335 Pfam PF13638 PIN domain 110 246 5.0E-6 T 01-11-2018 IPR002716 PIN domain AFULGI_00023560 c7bd8ba0826b820e683d84b8e5e2bde6 210 Gene3D G3DSA:3.40.50.150 37 210 7.4E-69 T 01-11-2018 AFULGI_00023560 c7bd8ba0826b820e683d84b8e5e2bde6 210 SUPERFAMILY SSF53335 9 206 3.77E-39 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFULGI_00023560 c7bd8ba0826b820e683d84b8e5e2bde6 210 PIRSF PIRSF006540 2 210 8.4E-81 T 01-11-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 AFULGI_00023560 c7bd8ba0826b820e683d84b8e5e2bde6 210 SMART SM01206 1 210 8.0E-108 T 01-11-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 AFULGI_00023560 c7bd8ba0826b820e683d84b8e5e2bde6 210 Gene3D G3DSA:3.30.200.20 1 36 1.4E-28 T 01-11-2018 AFULGI_00023560 c7bd8ba0826b820e683d84b8e5e2bde6 210 PRINTS PR00052 Fibrillarin signature 82 99 2.4E-36 T 01-11-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 AFULGI_00023560 c7bd8ba0826b820e683d84b8e5e2bde6 210 PRINTS PR00052 Fibrillarin signature 188 209 2.4E-36 T 01-11-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 AFULGI_00023560 c7bd8ba0826b820e683d84b8e5e2bde6 210 PRINTS PR00052 Fibrillarin signature 32 51 2.4E-36 T 01-11-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 AFULGI_00023560 c7bd8ba0826b820e683d84b8e5e2bde6 210 PRINTS PR00052 Fibrillarin signature 107 136 2.4E-36 T 01-11-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 AFULGI_00023560 c7bd8ba0826b820e683d84b8e5e2bde6 210 PRINTS PR00052 Fibrillarin signature 137 166 2.4E-36 T 01-11-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 AFULGI_00023560 c7bd8ba0826b820e683d84b8e5e2bde6 210 Hamap MF_00351 Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase [flpA]. 7 210 39.064 T 01-11-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 AFULGI_00023560 c7bd8ba0826b820e683d84b8e5e2bde6 210 ProSitePatterns PS00566 Fibrillarin signature. 82 95 - T 01-11-2018 IPR020813 Fibrillarin, conserved site GO:0003723|GO:0006364|GO:0008168 AFULGI_00023560 c7bd8ba0826b820e683d84b8e5e2bde6 210 Pfam PF01269 Fibrillarin 4 207 1.2E-67 T 01-11-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 AFULGI_00012090 5aef84061c4a22343de26f8ce7e2f446 323 Hamap MF_01446 tRNA N6-adenosine threonylcarbamoyltransferase [kae1]. 1 323 37.539 T 01-11-2018 IPR034680 tRNA N6-adenosine threonylcarbamoyltransferase Kae1/OSGEP GO:0000408|GO:0002949 Reactome: R-HSA-6782315 AFULGI_00012090 5aef84061c4a22343de26f8ce7e2f446 323 TIGRFAM TIGR03722 arch_KAE1: universal archaeal protein Kae1 4 322 1.4E-156 T 01-11-2018 IPR022449 tRNA N6-adenosine threonylcarbamoyltransferase Kae1, archaea GO:0000408|GO:0002949 AFULGI_00012090 5aef84061c4a22343de26f8ce7e2f446 323 Gene3D G3DSA:3.30.420.40 121 276 8.8E-103 T 01-11-2018 AFULGI_00012090 5aef84061c4a22343de26f8ce7e2f446 323 Gene3D G3DSA:3.30.420.40 3 299 8.8E-103 T 01-11-2018 AFULGI_00012090 5aef84061c4a22343de26f8ce7e2f446 323 SUPERFAMILY SSF53067 1 290 1.28E-34 T 01-11-2018 AFULGI_00012090 5aef84061c4a22343de26f8ce7e2f446 323 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 91 110 3.7E-40 T 01-11-2018 IPR017861 Kae1/TsaD family AFULGI_00012090 5aef84061c4a22343de26f8ce7e2f446 323 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 145 166 3.7E-40 T 01-11-2018 IPR017861 Kae1/TsaD family AFULGI_00012090 5aef84061c4a22343de26f8ce7e2f446 323 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 70 90 3.7E-40 T 01-11-2018 IPR017861 Kae1/TsaD family AFULGI_00012090 5aef84061c4a22343de26f8ce7e2f446 323 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 123 135 3.7E-40 T 01-11-2018 IPR017861 Kae1/TsaD family AFULGI_00012090 5aef84061c4a22343de26f8ce7e2f446 323 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 246 255 3.7E-40 T 01-11-2018 IPR017861 Kae1/TsaD family AFULGI_00012090 5aef84061c4a22343de26f8ce7e2f446 323 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 4 17 3.7E-40 T 01-11-2018 IPR017861 Kae1/TsaD family AFULGI_00012090 5aef84061c4a22343de26f8ce7e2f446 323 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 4 289 1.3E-109 T 01-11-2018 IPR017861 Kae1/TsaD family AFULGI_00012090 5aef84061c4a22343de26f8ce7e2f446 323 Pfam PF00814 Glycoprotease family 28 290 7.8E-91 T 01-11-2018 IPR000905 Gcp-like domain AFULGI_00009290 5ef575ad955efdb31c3f80075d03301f 381 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 229 375 1.4E-54 T 01-11-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AFULGI_00009290 5ef575ad955efdb31c3f80075d03301f 381 PIRSF PIRSF016578 6 378 2.6E-24 T 01-11-2018 AFULGI_00009290 5ef575ad955efdb31c3f80075d03301f 381 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 334 353 - T 01-11-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 AFULGI_00009290 5ef575ad955efdb31c3f80075d03301f 381 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 117 4.3E-37 T 01-11-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 AFULGI_00009290 5ef575ad955efdb31c3f80075d03301f 381 SUPERFAMILY SSF47203 225 378 4.19E-61 T 01-11-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 AFULGI_00009290 5ef575ad955efdb31c3f80075d03301f 381 Gene3D G3DSA:1.10.540.10 1 117 2.9E-41 T 01-11-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 AFULGI_00009290 5ef575ad955efdb31c3f80075d03301f 381 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 121 215 3.6E-26 T 01-11-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 AFULGI_00009290 5ef575ad955efdb31c3f80075d03301f 381 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 123 135 - T 01-11-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 AFULGI_00009290 5ef575ad955efdb31c3f80075d03301f 381 Gene3D G3DSA:2.40.110.10 120 232 3.9E-38 T 01-11-2018 AFULGI_00009290 5ef575ad955efdb31c3f80075d03301f 381 SUPERFAMILY SSF56645 1 238 7.07E-82 T 01-11-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 AFULGI_00009290 5ef575ad955efdb31c3f80075d03301f 381 Gene3D G3DSA:1.20.140.10 233 380 6.7E-59 T 01-11-2018 AFULGI_00023130 84a3be2b410a462af01034c832370e27 195 TIGRFAM TIGR00164 PS_decarb_rel: phosphatidylserine decarboxylase homolog 1 192 7.0E-80 T 01-11-2018 IPR033175 Phosphatidylserine decarboxylase, archaeal-type KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 AFULGI_00023130 84a3be2b410a462af01034c832370e27 195 Pfam PF02666 Phosphatidylserine decarboxylase 34 186 7.6E-25 T 01-11-2018 IPR003817 Phosphatidylserine decarboxylase-related GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 AFULGI_00023130 84a3be2b410a462af01034c832370e27 195 Hamap MF_00664 Phosphatidylserine decarboxylase proenzyme [psd]. 1 190 32.585 T 01-11-2018 IPR033175 Phosphatidylserine decarboxylase, archaeal-type KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 AFULGI_00002020 624389511aeb235e07676edbb3bd4e77 247 PIRSF PIRSF017269 1 247 3.7E-67 T 01-11-2018 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 MetaCyc: PWY-6829 AFULGI_00002020 624389511aeb235e07676edbb3bd4e77 247 Gene3D G3DSA:3.10.330.20 5 56 5.8E-12 T 01-11-2018 AFULGI_00002020 624389511aeb235e07676edbb3bd4e77 247 SUPERFAMILY SSF53335 15 245 2.13E-53 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFULGI_00002020 624389511aeb235e07676edbb3bd4e77 247 Gene3D G3DSA:3.40.50.150 62 247 1.1E-40 T 01-11-2018 AFULGI_00002020 624389511aeb235e07676edbb3bd4e77 247 Pfam PF08704 tRNA methyltransferase complex GCD14 subunit 75 227 1.2E-12 T 01-11-2018 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 MetaCyc: PWY-6829 AFULGI_00015390 c797d5322ff32ddbcda2e39f81a52c3c 380 TIGRFAM TIGR02535 hyp_Hser_kinase: proposed homoserine kinase 1 379 3.9E-167 T 01-11-2018 IPR023665 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, prokaryotes GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFULGI_00015390 c797d5322ff32ddbcda2e39f81a52c3c 380 Hamap MF_01402_A 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [apgM]. 1 380 39.757 T 01-11-2018 IPR023665 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, prokaryotes GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFULGI_00015390 c797d5322ff32ddbcda2e39f81a52c3c 380 PIRSF PIRSF006392 1 380 8.8E-127 T 01-11-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFULGI_00015390 c797d5322ff32ddbcda2e39f81a52c3c 380 Gene3D G3DSA:3.40.720.10 4 375 2.0E-115 T 01-11-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 AFULGI_00015390 c797d5322ff32ddbcda2e39f81a52c3c 380 Gene3D G3DSA:3.30.70.2130 78 210 2.0E-115 T 01-11-2018 AFULGI_00015390 c797d5322ff32ddbcda2e39f81a52c3c 380 SUPERFAMILY SSF53649 1 349 5.45E-33 T 01-11-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 AFULGI_00015390 c797d5322ff32ddbcda2e39f81a52c3c 380 Pfam PF01676 Metalloenzyme superfamily 1 379 8.4E-50 T 01-11-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 AFULGI_00015390 c797d5322ff32ddbcda2e39f81a52c3c 380 Pfam PF10143 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 37 193 1.1E-48 T 01-11-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFULGI_00015390 c797d5322ff32ddbcda2e39f81a52c3c 380 TIGRFAM TIGR00306 apgM: phosphoglycerate mutase (2,3-diphosphoglycerate-independent), archaeal form 4 379 2.6E-157 T 01-11-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFULGI_00001040 b00f4255722d9ca4ef631cbfdfc0f684 153 SUPERFAMILY SSF54893 3 98 9.55E-34 T 01-11-2018 IPR036793 Aspartate carbamoyltransferase regulatory subunit, N-terminal domain superfamily AFULGI_00001040 b00f4255722d9ca4ef631cbfdfc0f684 153 Hamap MF_00002 Aspartate carbamoyltransferase regulatory chain [pyrI]. 1 152 32.65 T 01-11-2018 IPR002801 Aspartate transcarbamylase regulatory subunit GO:0006207|GO:0009347 AFULGI_00001040 b00f4255722d9ca4ef631cbfdfc0f684 153 Gene3D G3DSA:2.30.30.20 98 149 4.2E-15 T 01-11-2018 AFULGI_00001040 b00f4255722d9ca4ef631cbfdfc0f684 153 SUPERFAMILY SSF57825 99 146 7.06E-11 T 01-11-2018 IPR036792 Aspartate carbamoyltransferase regulatory subunit, C-terminal domain superfamily AFULGI_00001040 b00f4255722d9ca4ef631cbfdfc0f684 153 Pfam PF01948 Aspartate carbamoyltransferase regulatory chain, allosteric domain 5 95 3.0E-33 T 01-11-2018 IPR020545 Aspartate carbamoyltransferase regulatory subunit, N-terminal AFULGI_00001040 b00f4255722d9ca4ef631cbfdfc0f684 153 Gene3D G3DSA:3.30.70.140 1 96 2.8E-36 T 01-11-2018 IPR036793 Aspartate carbamoyltransferase regulatory subunit, N-terminal domain superfamily AFULGI_00001040 b00f4255722d9ca4ef631cbfdfc0f684 153 TIGRFAM TIGR00240 ATCase_reg: aspartate carbamoyltransferase, regulatory subunit 2 152 1.2E-73 T 01-11-2018 IPR002801 Aspartate transcarbamylase regulatory subunit GO:0006207|GO:0009347 AFULGI_00001040 b00f4255722d9ca4ef631cbfdfc0f684 153 Pfam PF02748 Aspartate carbamoyltransferase regulatory chain, metal binding domain 101 147 2.1E-15 T 01-11-2018 IPR020542 Aspartate carbamoyltransferase regulatory subunit, C-terminal AFULGI_00001040 b00f4255722d9ca4ef631cbfdfc0f684 153 ProDom PD006194 REGULATORY ASPARTATE CARBAMOYLTRANSFERASE CHAIN METAL-BINDING ZINC PYRIMIDINE BIOSYNTHESIS SUBUNIT TRANSFERASE 6 96 1.0E-45 T 01-11-2018 IPR020545 Aspartate carbamoyltransferase regulatory subunit, N-terminal AFULGI_00007680 0a56dea0b937051802366e76b0dee9c1 549 Gene3D G3DSA:3.40.50.12780 13 443 8.3E-100 T 01-11-2018 AFULGI_00007680 0a56dea0b937051802366e76b0dee9c1 549 ProSitePatterns PS00455 Putative AMP-binding domain signature. 199 210 - T 01-11-2018 IPR020845 AMP-binding, conserved site AFULGI_00007680 0a56dea0b937051802366e76b0dee9c1 549 Gene3D G3DSA:3.30.300.310 444 549 2.0E-34 T 01-11-2018 AFULGI_00007680 0a56dea0b937051802366e76b0dee9c1 549 SUPERFAMILY SSF56801 22 546 4.45E-148 T 01-11-2018 AFULGI_00007680 0a56dea0b937051802366e76b0dee9c1 549 Pfam PF13193 AMP-binding enzyme C-terminal domain 456 533 3.1E-21 T 01-11-2018 IPR025110 AMP-binding enzyme, C-terminal domain AFULGI_00007680 0a56dea0b937051802366e76b0dee9c1 549 Pfam PF00501 AMP-binding enzyme 35 447 1.2E-100 T 01-11-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFULGI_00021460 e6b66355fac8bb3c620cd84dfa997a7e 604 Pfam PF04566 RNA polymerase Rpb2, domain 4 6 67 5.5E-24 T 01-11-2018 IPR007646 RNA polymerase Rpb2, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFULGI_00021460 e6b66355fac8bb3c620cd84dfa997a7e 604 Pfam PF04560 RNA polymerase Rpb2, domain 7 509 599 3.7E-33 T 01-11-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFULGI_00021460 e6b66355fac8bb3c620cd84dfa997a7e 604 Pfam PF00562 RNA polymerase Rpb2, domain 6 137 507 3.0E-128 T 01-11-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFULGI_00021460 e6b66355fac8bb3c620cd84dfa997a7e 604 TIGRFAM TIGR03670 rpoB_arch: DNA-directed RNA polymerase subunit B 6 603 0.0 T 01-11-2018 IPR019969 DNA-directed RNA polymerase subunit B (Rpo2) GO:0003677|GO:0003899|GO:0006351|GO:0008270 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFULGI_00021460 e6b66355fac8bb3c620cd84dfa997a7e 604 ProSitePatterns PS01166 RNA polymerases beta chain signature. 360 372 - T 01-11-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFULGI_00021460 e6b66355fac8bb3c620cd84dfa997a7e 604 Gene3D G3DSA:3.90.1800.10 494 602 1.1E-42 T 01-11-2018 AFULGI_00021460 e6b66355fac8bb3c620cd84dfa997a7e 604 Gene3D G3DSA:3.90.1070.20 1 55 1.4E-18 T 01-11-2018 AFULGI_00021460 e6b66355fac8bb3c620cd84dfa997a7e 604 SUPERFAMILY SSF64484 4 602 1.31E-234 T 01-11-2018 AFULGI_00021460 e6b66355fac8bb3c620cd84dfa997a7e 604 Gene3D G3DSA:2.40.270.10 137 493 8.8E-139 T 01-11-2018 IPR037033 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFULGI_00021460 e6b66355fac8bb3c620cd84dfa997a7e 604 Gene3D G3DSA:2.40.50.150 166 356 8.8E-139 T 01-11-2018 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFULGI_00021460 e6b66355fac8bb3c620cd84dfa997a7e 604 Pfam PF04567 RNA polymerase Rpb2, domain 5 89 128 5.8E-9 T 01-11-2018 IPR007647 RNA polymerase Rpb2, domain 5 GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFULGI_00013770 5c76ccf21cb1bc1ab59d0262bfb28d81 90 Gene3D G3DSA:3.40.50.300 2 90 1.0E-6 T 01-11-2018 AFULGI_00013770 5c76ccf21cb1bc1ab59d0262bfb28d81 90 SUPERFAMILY SSF52540 10 89 7.97E-8 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00026100 cf862c6d78a3c22fee067d8916e8c5cf 261 Hamap MF_00055 MEMO1 family protein . 1 260 60.764 T 01-11-2018 IPR002737 MEMO1 family Reactome: R-HSA-6785631 AFULGI_00026100 cf862c6d78a3c22fee067d8916e8c5cf 261 Pfam PF01875 Memo-like protein 3 258 1.2E-84 T 01-11-2018 IPR002737 MEMO1 family Reactome: R-HSA-6785631 AFULGI_00026100 cf862c6d78a3c22fee067d8916e8c5cf 261 Gene3D G3DSA:3.40.830.10 1 261 6.1E-60 T 01-11-2018 AFULGI_00026100 cf862c6d78a3c22fee067d8916e8c5cf 261 TIGRFAM TIGR04336 AmmeMemoSam_B: AmmeMemoRadiSam system protein B 2 259 5.5E-91 T 01-11-2018 AFULGI_00026100 cf862c6d78a3c22fee067d8916e8c5cf 261 SUPERFAMILY SSF53213 59 192 7.59E-5 T 01-11-2018 AFULGI_00010270 c313a2862c5da5c1254428733022b3cf 423 Hamap MF_00118_A Elongation factor Tu [tuf]. 2 422 62.375 T 01-11-2018 IPR004539 Translation elongation factor EF1A, eukaryotic/archaeal GO:0003746|GO:0005525|GO:0005737|GO:0006414 Reactome: R-HSA-156842 AFULGI_00010270 c313a2862c5da5c1254428733022b3cf 423 Gene3D G3DSA:2.40.30.10 314 419 4.1E-42 T 01-11-2018 AFULGI_00010270 c313a2862c5da5c1254428733022b3cf 423 SUPERFAMILY SSF50447 222 312 1.54E-31 T 01-11-2018 IPR009000 Translation protein, beta-barrel domain superfamily AFULGI_00010270 c313a2862c5da5c1254428733022b3cf 423 Gene3D G3DSA:3.40.50.300 1 215 6.0E-90 T 01-11-2018 AFULGI_00010270 c313a2862c5da5c1254428733022b3cf 423 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 61 76 - T 01-11-2018 IPR031157 Tr-type G domain, conserved site AFULGI_00010270 c313a2862c5da5c1254428733022b3cf 423 Pfam PF03143 Elongation factor Tu C-terminal domain 313 418 2.3E-37 T 01-11-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal AFULGI_00010270 c313a2862c5da5c1254428733022b3cf 423 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 7 193 6.6E-18 T 01-11-2018 IPR005225 Small GTP-binding protein domain GO:0005525 AFULGI_00010270 c313a2862c5da5c1254428733022b3cf 423 SUPERFAMILY SSF52540 3 240 4.76E-79 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00010270 c313a2862c5da5c1254428733022b3cf 423 TIGRFAM TIGR00483 EF-1_alpha: translation elongation factor EF-1, subunit alpha 1 423 3.8E-256 T 01-11-2018 IPR004539 Translation elongation factor EF1A, eukaryotic/archaeal GO:0003746|GO:0005525|GO:0005737|GO:0006414 Reactome: R-HSA-156842 AFULGI_00010270 c313a2862c5da5c1254428733022b3cf 423 SUPERFAMILY SSF50465 315 419 2.73E-39 T 01-11-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal AFULGI_00010270 c313a2862c5da5c1254428733022b3cf 423 Pfam PF03144 Elongation factor Tu domain 2 239 304 5.5E-18 T 01-11-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 AFULGI_00010270 c313a2862c5da5c1254428733022b3cf 423 Pfam PF00009 Elongation factor Tu GTP binding domain 5 213 4.8E-60 T 01-11-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFULGI_00010270 c313a2862c5da5c1254428733022b3cf 423 Gene3D G3DSA:2.40.30.10 221 313 1.0E-39 T 01-11-2018 AFULGI_00010270 c313a2862c5da5c1254428733022b3cf 423 PRINTS PR00315 GTP-binding elongation factor signature 104 115 2.3E-24 T 01-11-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFULGI_00010270 c313a2862c5da5c1254428733022b3cf 423 PRINTS PR00315 GTP-binding elongation factor signature 88 98 2.3E-24 T 01-11-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFULGI_00010270 c313a2862c5da5c1254428733022b3cf 423 PRINTS PR00315 GTP-binding elongation factor signature 141 150 2.3E-24 T 01-11-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFULGI_00010270 c313a2862c5da5c1254428733022b3cf 423 PRINTS PR00315 GTP-binding elongation factor signature 9 22 2.3E-24 T 01-11-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFULGI_00010270 c313a2862c5da5c1254428733022b3cf 423 PRINTS PR00315 GTP-binding elongation factor signature 68 76 2.3E-24 T 01-11-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFULGI_00000590 fc695bec27ccd0a0053daa975cdd7d47 76 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 6 45 6.6E-10 T 01-11-2018 IPR007159 SpoVT-AbrB domain GO:0003677 AFULGI_00000590 fc695bec27ccd0a0053daa975cdd7d47 76 Gene3D G3DSA:2.10.260.10 2 44 2.2E-12 T 01-11-2018 AFULGI_00000590 fc695bec27ccd0a0053daa975cdd7d47 76 SMART SM00966 6 49 6.0E-12 T 01-11-2018 IPR007159 SpoVT-AbrB domain GO:0003677 AFULGI_00000590 fc695bec27ccd0a0053daa975cdd7d47 76 SUPERFAMILY SSF89447 5 47 2.27E-12 T 01-11-2018 IPR037914 SpoVT-AbrB domain superfamily AFULGI_00000590 fc695bec27ccd0a0053daa975cdd7d47 76 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 5 45 9.0E-14 T 01-11-2018 IPR007159 SpoVT-AbrB domain GO:0003677 AFULGI_00011980 2fe4b27b7edbec36edcf4e38ec90dca7 181 Hamap MF_01134 Acetyl-CoA decarbonylase/synthase complex subunit epsilon [cdhB]. 8 180 38.124 T 01-11-2018 IPR003704 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit GO:0019385 AFULGI_00011980 2fe4b27b7edbec36edcf4e38ec90dca7 181 TIGRFAM TIGR00315 cdhB: CO dehydrogenase/acetyl-CoA synthase complex, epsilon subunit 15 180 3.8E-76 T 01-11-2018 IPR003704 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit GO:0019385 AFULGI_00011980 2fe4b27b7edbec36edcf4e38ec90dca7 181 PIRSF PIRSF006035 5 181 4.7E-77 T 01-11-2018 IPR003704 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit GO:0019385 AFULGI_00011980 2fe4b27b7edbec36edcf4e38ec90dca7 181 Pfam PF02552 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit 5 178 2.2E-67 T 01-11-2018 IPR003704 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit GO:0019385 AFULGI_00011980 2fe4b27b7edbec36edcf4e38ec90dca7 181 Gene3D G3DSA:3.40.50.1220 20 181 1.9E-56 T 01-11-2018 AFULGI_00011980 2fe4b27b7edbec36edcf4e38ec90dca7 181 SUPERFAMILY SSF52467 25 181 2.13E-48 T 01-11-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily AFULGI_00000060 2c04147c230908dd179a3fd3039119bb 414 SUPERFAMILY SSF103473 4 398 1.14E-38 T 01-11-2018 IPR036259 MFS transporter superfamily AFULGI_00000060 2c04147c230908dd179a3fd3039119bb 414 Gene3D G3DSA:1.20.1250.20 1 399 1.1E-34 T 01-11-2018 AFULGI_00000060 2c04147c230908dd179a3fd3039119bb 414 Pfam PF07690 Major Facilitator Superfamily 7 261 2.9E-18 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFULGI_00002820 6d17fbea05dea11c67451280cfdc13d1 172 Hamap MF_00065 Adenylyl-sulfate kinase [cysC]. 1 170 35.374 T 01-11-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 AFULGI_00002820 6d17fbea05dea11c67451280cfdc13d1 172 TIGRFAM TIGR00455 apsK: adenylyl-sulfate kinase 2 165 1.8E-77 T 01-11-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 AFULGI_00002820 6d17fbea05dea11c67451280cfdc13d1 172 Gene3D G3DSA:3.40.50.300 2 172 3.6E-62 T 01-11-2018 AFULGI_00002820 6d17fbea05dea11c67451280cfdc13d1 172 Pfam PF01583 Adenylylsulphate kinase 2 153 2.6E-63 T 01-11-2018 AFULGI_00002820 6d17fbea05dea11c67451280cfdc13d1 172 SUPERFAMILY SSF52540 3 169 2.06E-38 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00024790 7ff6c7515ee5a6a7a214867c9d4dd201 297 Hamap MF_00579 Formylmethanofuran--tetrahydromethanopterin formyltransferase [ftr]. 1 297 45.51 T 01-11-2018 IPR014053 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr GO:0006730|GO:0030270 AFULGI_00024790 7ff6c7515ee5a6a7a214867c9d4dd201 297 TIGRFAM TIGR03119 one_C_fhcD: formylmethanofuran--tetrahydromethanopterin N-formyltransferase 8 296 1.2E-145 T 01-11-2018 IPR014053 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr GO:0006730|GO:0030270 AFULGI_00024790 7ff6c7515ee5a6a7a214867c9d4dd201 297 Pfam PF01913 Formylmethanofuran-tetrahydromethanopterin formyltransferase 1 144 6.4E-61 T 01-11-2018 IPR022667 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr, N-terminal GO:0006730|GO:0016740 AFULGI_00024790 7ff6c7515ee5a6a7a214867c9d4dd201 297 Gene3D G3DSA:3.30.70.520 3 296 3.5E-137 T 01-11-2018 IPR023447 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr, ferredoxin-like superfamily AFULGI_00024790 7ff6c7515ee5a6a7a214867c9d4dd201 297 PIRSF PIRSF006414 1 297 3.2E-149 T 01-11-2018 IPR014053 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr GO:0006730|GO:0030270 AFULGI_00024790 7ff6c7515ee5a6a7a214867c9d4dd201 297 SUPERFAMILY SSF55112 146 297 6.54E-62 T 01-11-2018 IPR023447 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr, ferredoxin-like superfamily AFULGI_00024790 7ff6c7515ee5a6a7a214867c9d4dd201 297 Pfam PF02741 FTR, proximal lobe 147 296 1.4E-65 T 01-11-2018 IPR002770 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr, C-terminal GO:0006730|GO:0016740 AFULGI_00024790 7ff6c7515ee5a6a7a214867c9d4dd201 297 SUPERFAMILY SSF55112 1 145 1.39E-60 T 01-11-2018 IPR023447 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr, ferredoxin-like superfamily AFULGI_00024790 7ff6c7515ee5a6a7a214867c9d4dd201 297 Gene3D G3DSA:3.30.70.520 17 162 3.5E-137 T 01-11-2018 IPR023447 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr, ferredoxin-like superfamily AFULGI_00007320 ff1a6a4263d47699ab72868c68d9ee73 602 PIRSF PIRSF006553 1 563 8.1E-230 T 01-11-2018 IPR005734 DNA topoisomerase VI, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AFULGI_00007320 ff1a6a4263d47699ab72868c68d9ee73 602 Gene3D G3DSA:1.10.10.1960 462 500 9.2E-8 T 01-11-2018 AFULGI_00007320 ff1a6a4263d47699ab72868c68d9ee73 602 SMART SM00387 25 146 1.6E-9 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFULGI_00007320 ff1a6a4263d47699ab72868c68d9ee73 602 Gene3D G3DSA:1.10.8.50 226 301 1.7E-25 T 01-11-2018 AFULGI_00007320 ff1a6a4263d47699ab72868c68d9ee73 602 Gene3D G3DSA:3.30.230.10 303 461 7.4E-64 T 01-11-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AFULGI_00007320 ff1a6a4263d47699ab72868c68d9ee73 602 SUPERFAMILY SSF46946 226 298 9.06E-8 T 01-11-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 AFULGI_00007320 ff1a6a4263d47699ab72868c68d9ee73 602 Gene3D G3DSA:2.60.40.2960 501 601 1.7E-11 T 01-11-2018 AFULGI_00007320 ff1a6a4263d47699ab72868c68d9ee73 602 SUPERFAMILY SSF54211 302 466 1.74E-62 T 01-11-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFULGI_00007320 ff1a6a4263d47699ab72868c68d9ee73 602 ProDom PD013790 TOPOISOMERASE ISOMERASE SUBUNIT DNA B VI TYPE II NUCLEOTIDE-BINDING ATP-BINDING 303 484 7.0E-92 T 01-11-2018 IPR015320 DNA topoisomerase VI, subunit B, transducer GO:0003677|GO:0003918|GO:0006265 AFULGI_00007320 ff1a6a4263d47699ab72868c68d9ee73 602 Gene3D G3DSA:3.30.565.10 1 225 2.1E-79 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFULGI_00007320 ff1a6a4263d47699ab72868c68d9ee73 602 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 29 127 1.8E-13 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFULGI_00007320 ff1a6a4263d47699ab72868c68d9ee73 602 SUPERFAMILY SSF55874 12 223 9.04E-32 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFULGI_00007320 ff1a6a4263d47699ab72868c68d9ee73 602 Pfam PF09239 Topoisomerase VI B subunit, transducer 303 465 1.1E-65 T 01-11-2018 IPR015320 DNA topoisomerase VI, subunit B, transducer GO:0003677|GO:0003918|GO:0006265 AFULGI_00007320 ff1a6a4263d47699ab72868c68d9ee73 602 Hamap MF_00322 Type 2 DNA topoisomerase 6 subunit B [top6B]. 2 508 32.459 T 01-11-2018 IPR005734 DNA topoisomerase VI, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AFULGI_00007320 ff1a6a4263d47699ab72868c68d9ee73 602 TIGRFAM TIGR01052 top6b: DNA topoisomerase VI, B subunit 3 487 1.2E-230 T 01-11-2018 IPR005734 DNA topoisomerase VI, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AFULGI_00010570 e977f113d8c42548eb33964117096ebc 400 SUPERFAMILY SSF53901 16 240 6.62E-33 T 01-11-2018 IPR016039 Thiolase-like GO:0003824 AFULGI_00010570 e977f113d8c42548eb33964117096ebc 400 PIRSF PIRSF000429 12 396 8.5E-30 T 01-11-2018 IPR002155 Thiolase GO:0016747 AFULGI_00010570 e977f113d8c42548eb33964117096ebc 400 SUPERFAMILY SSF53901 248 376 5.26E-18 T 01-11-2018 IPR016039 Thiolase-like GO:0003824 AFULGI_00010570 e977f113d8c42548eb33964117096ebc 400 Pfam PF00108 Thiolase, N-terminal domain 17 135 3.4E-9 T 01-11-2018 IPR020616 Thiolase, N-terminal GO:0016747 AFULGI_00010570 e977f113d8c42548eb33964117096ebc 400 Gene3D G3DSA:3.40.47.10 12 398 1.7E-88 T 01-11-2018 IPR016039 Thiolase-like GO:0003824 AFULGI_00016800 fd0ae19eeb1f8039bd7d5e267da4f2ce 183 Pfam PF01944 Stage II sporulation protein M 12 171 6.0E-31 T 01-11-2018 IPR002798 Stage II sporulation protein M-like AFULGI_00004200 96b04141251f58e7f34c39e57dc7adad 158 Pfam PF11655 Protein of unknown function (DUF2589) 8 151 4.7E-25 T 01-11-2018 IPR024510 Protein of unknown function DUF2589 AFULGI_00004200 96b04141251f58e7f34c39e57dc7adad 158 ProDom PD104924 XAC1607 AF0417 6 154 2.0E-13 T 01-11-2018 AFULGI_00006650 a181bd047edd8172edd6b679a6bf15ae 306 TIGRFAM TIGR03455 HisG_C-term: ATP phosphoribosyltransferase, C-terminal domain 204 302 3.0E-23 T 01-11-2018 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 AFULGI_00006650 a181bd047edd8172edd6b679a6bf15ae 306 Gene3D G3DSA:3.40.190.10 97 197 9.5E-42 T 01-11-2018 AFULGI_00006650 a181bd047edd8172edd6b679a6bf15ae 306 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 9 195 1.6E-29 T 01-11-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 AFULGI_00006650 a181bd047edd8172edd6b679a6bf15ae 306 Pfam PF01634 ATP phosphoribosyltransferase 53 225 2.3E-31 T 01-11-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 AFULGI_00006650 a181bd047edd8172edd6b679a6bf15ae 306 Gene3D G3DSA:3.40.190.10 12 218 9.5E-42 T 01-11-2018 AFULGI_00006650 a181bd047edd8172edd6b679a6bf15ae 306 SUPERFAMILY SSF53850 8 229 1.78E-31 T 01-11-2018 AFULGI_00000990 f45f58898f2bcbb34d62534d0e1ecf70 188 SUPERFAMILY SSF46785 15 85 4.07E-11 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00000990 f45f58898f2bcbb34d62534d0e1ecf70 188 Gene3D G3DSA:1.10.10.10 8 92 4.7E-9 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00000990 f45f58898f2bcbb34d62534d0e1ecf70 188 Pfam PF14947 Winged helix-turn-helix 18 80 1.0E-5 T 01-11-2018 IPR038723 ArnR1-like, winged helix-turn-helix domain AFULGI_00019190 374bd7d04709e9cdcc634b078436f19e 643 Pfam PF00890 FAD binding domain 24 263 8.2E-16 T 01-11-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFULGI_00019190 374bd7d04709e9cdcc634b078436f19e 643 Pfam PF02910 Fumarate reductase flavoprotein C-term 520 632 3.8E-8 T 01-11-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFULGI_00019190 374bd7d04709e9cdcc634b078436f19e 643 SUPERFAMILY SSF51905 3 498 2.16E-80 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFULGI_00019190 374bd7d04709e9cdcc634b078436f19e 643 Gene3D G3DSA:3.90.700.10 282 411 1.7E-294 T 01-11-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFULGI_00019190 374bd7d04709e9cdcc634b078436f19e 643 SUPERFAMILY SSF46977 507 641 5.89E-46 T 01-11-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFULGI_00019190 374bd7d04709e9cdcc634b078436f19e 643 TIGRFAM TIGR02061 aprA: adenylylsulfate reductase, alpha subunit 24 639 0.0 T 01-11-2018 IPR011803 Adenylylsulphate reductase, alpha subunit KEGG: 00920+1.8.99.2|MetaCyc: PWY-5278|MetaCyc: PWY-5279 AFULGI_00019190 374bd7d04709e9cdcc634b078436f19e 643 SUPERFAMILY SSF56425 257 400 4.92E-64 T 01-11-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFULGI_00019190 374bd7d04709e9cdcc634b078436f19e 643 Gene3D G3DSA:3.50.50.90 22 638 1.7E-294 T 01-11-2018 AFULGI_00019190 374bd7d04709e9cdcc634b078436f19e 643 PIRSF PIRSF000171 13 642 6.7E-250 T 01-11-2018 AFULGI_00014880 4c3b336d94fcf022a74b02603380f804 160 Pfam PF13534 4Fe-4S dicluster domain 26 86 4.0E-9 T 01-11-2018 AFULGI_00014880 4c3b336d94fcf022a74b02603380f804 160 Gene3D G3DSA:3.30.70.3270 8 146 4.0E-9 T 01-11-2018 AFULGI_00014880 4c3b336d94fcf022a74b02603380f804 160 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 27 38 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFULGI_00014880 4c3b336d94fcf022a74b02603380f804 160 SUPERFAMILY SSF46548 23 101 7.32E-17 T 01-11-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 AFULGI_00014590 e7508441e59bdc20506f5528678be50d 85 Gene3D G3DSA:1.10.10.10 2 84 4.6E-13 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00014590 e7508441e59bdc20506f5528678be50d 85 SUPERFAMILY SSF46785 5 71 8.17E-6 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00018530 8023bdce639dca6ab35afd12148d1a47 411 Gene3D G3DSA:3.60.120.10 2 411 2.4E-124 T 01-11-2018 IPR005801 ADC synthase GO:0009058 AFULGI_00018530 8023bdce639dca6ab35afd12148d1a47 411 Pfam PF00425 chorismate binding enzyme 152 401 1.0E-85 T 01-11-2018 IPR015890 Chorismate-utilising enzyme, C-terminal AFULGI_00018530 8023bdce639dca6ab35afd12148d1a47 411 Pfam PF04715 Anthranilate synthase component I, N terminal region 7 119 1.2E-12 T 01-11-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 AFULGI_00018530 8023bdce639dca6ab35afd12148d1a47 411 SUPERFAMILY SSF56322 6 410 3.53E-113 T 01-11-2018 IPR005801 ADC synthase GO:0009058 AFULGI_00018530 8023bdce639dca6ab35afd12148d1a47 411 TIGRFAM TIGR01820 TrpE-arch: anthranilate synthase component I 9 410 8.4E-156 T 01-11-2018 IPR010116 Anthranilate synthase component I, archaeal type GO:0000162|GO:0004049 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 AFULGI_00018530 8023bdce639dca6ab35afd12148d1a47 411 PRINTS PR00095 Anthranilate synthase component I signature 345 359 1.7E-17 T 01-11-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 AFULGI_00018530 8023bdce639dca6ab35afd12148d1a47 411 PRINTS PR00095 Anthranilate synthase component I signature 265 278 1.7E-17 T 01-11-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 AFULGI_00018530 8023bdce639dca6ab35afd12148d1a47 411 PRINTS PR00095 Anthranilate synthase component I signature 251 264 1.7E-17 T 01-11-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 AFULGI_00018530 8023bdce639dca6ab35afd12148d1a47 411 PRINTS PR00095 Anthranilate synthase component I signature 359 373 1.7E-17 T 01-11-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 AFULGI_00003070 8a268324fdb971f490fced19053b547d 150 SMART SM00670 1 141 3.1E-26 T 01-11-2018 IPR002716 PIN domain AFULGI_00003070 8a268324fdb971f490fced19053b547d 150 SUPERFAMILY SSF88723 1 144 8.69E-21 T 01-11-2018 IPR029060 PIN-like domain superfamily AFULGI_00003070 8a268324fdb971f490fced19053b547d 150 Gene3D G3DSA:3.40.50.1010 2 149 9.8E-15 T 01-11-2018 AFULGI_00003070 8a268324fdb971f490fced19053b547d 150 Pfam PF01850 PIN domain 3 145 2.0E-33 T 01-11-2018 IPR002716 PIN domain AFULGI_00018390 f256cbff71d61641759378696166c310 408 Gene3D G3DSA:3.40.50.720 4 364 1.8E-81 T 01-11-2018 AFULGI_00018390 f256cbff71d61641759378696166c310 408 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 4 126 8.5E-20 T 01-11-2018 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 AFULGI_00018390 f256cbff71d61641759378696166c310 408 Pfam PF16653 Saccharopine dehydrogenase C-terminal domain 179 375 1.5E-9 T 01-11-2018 IPR032095 Saccharopine dehydrogenase, C-terminal Reactome: R-HSA-71064 AFULGI_00018390 f256cbff71d61641759378696166c310 408 Gene3D G3DSA:3.30.360.10 132 326 1.8E-81 T 01-11-2018 AFULGI_00018390 f256cbff71d61641759378696166c310 408 SUPERFAMILY SSF51735 1 160 9.13E-22 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily AFULGI_00008280 92342f55daf167dfd50f8b82d24367c7 280 Pfam PF01678 Diaminopimelate epimerase 5 127 2.0E-43 T 01-11-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 AFULGI_00008280 92342f55daf167dfd50f8b82d24367c7 280 Pfam PF01678 Diaminopimelate epimerase 154 266 5.1E-24 T 01-11-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 AFULGI_00008280 92342f55daf167dfd50f8b82d24367c7 280 ProSitePatterns PS01326 Diaminopimelate epimerase signature. 67 81 - T 01-11-2018 IPR018510 Diaminopimelate epimerase, active site GO:0005737|GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 AFULGI_00008280 92342f55daf167dfd50f8b82d24367c7 280 Gene3D G3DSA:3.10.310.10 5 269 1.4E-88 T 01-11-2018 AFULGI_00008280 92342f55daf167dfd50f8b82d24367c7 280 Gene3D G3DSA:3.10.310.10 123 263 1.4E-88 T 01-11-2018 AFULGI_00008280 92342f55daf167dfd50f8b82d24367c7 280 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 3 273 37.534 T 01-11-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 AFULGI_00008280 92342f55daf167dfd50f8b82d24367c7 280 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 3 271 2.1E-99 T 01-11-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 AFULGI_00008280 92342f55daf167dfd50f8b82d24367c7 280 SUPERFAMILY SSF54506 141 271 2.51E-36 T 01-11-2018 AFULGI_00008280 92342f55daf167dfd50f8b82d24367c7 280 SUPERFAMILY SSF54506 3 133 3.31E-42 T 01-11-2018 AFULGI_00017850 69bed08265162aff7cef6691876d327f 195 Gene3D G3DSA:1.10.150.280 88 185 3.4E-43 T 01-11-2018 AFULGI_00017850 69bed08265162aff7cef6691876d327f 195 SUPERFAMILY SSF160975 16 195 2.88E-97 T 01-11-2018 AFULGI_00017850 69bed08265162aff7cef6691876d327f 195 Gene3D G3DSA:2.40.50.140 16 87 8.5E-33 T 01-11-2018 AFULGI_00017850 69bed08265162aff7cef6691876d327f 195 Pfam PF04919 Protein of unknown function (DUF655) 15 194 1.0E-82 T 01-11-2018 IPR007003 Protein of unknown function DUF655 AFULGI_00025760 f0b3d494f486ac362e8a7b6a631c234d 330 TIGRFAM TIGR04337 AmmeMemoSam_rS: AmmeMemoRadiSam system radical SAM enzyme 10 329 2.0E-69 T 01-11-2018 IPR027596 AmmeMemoRadiSam system radical SAM enzyme AFULGI_00025760 f0b3d494f486ac362e8a7b6a631c234d 330 Pfam PF04055 Radical SAM superfamily 77 225 4.5E-19 T 01-11-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFULGI_00025760 f0b3d494f486ac362e8a7b6a631c234d 330 Gene3D G3DSA:3.20.20.70 74 323 1.4E-23 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFULGI_00025760 f0b3d494f486ac362e8a7b6a631c234d 330 SUPERFAMILY SSF102114 55 307 7.06E-35 T 01-11-2018 AFULGI_00025760 f0b3d494f486ac362e8a7b6a631c234d 330 PIRSF PIRSF004869 1 306 2.3E-94 T 01-11-2018 IPR016431 Pyruvate-formate lyase-activating enzyme, predicted AFULGI_00020960 0f227c23b9207a0445523666869831b2 291 Hamap MF_01975 Methionine aminopeptidase [map]. 6 290 46.982 T 01-11-2018 IPR028595 Methionine aminopeptidase, archaeal GO:0004177|GO:0006508 MetaCyc: PWY-7799|MetaCyc: PWY-7800 AFULGI_00020960 0f227c23b9207a0445523666869831b2 291 SUPERFAMILY SSF46785 196 266 4.22E-15 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00020960 0f227c23b9207a0445523666869831b2 291 PRINTS PR00599 Methionine aminopeptidase-1 signature 55 68 1.2E-17 T 01-11-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 AFULGI_00020960 0f227c23b9207a0445523666869831b2 291 PRINTS PR00599 Methionine aminopeptidase-1 signature 177 189 1.2E-17 T 01-11-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 AFULGI_00020960 0f227c23b9207a0445523666869831b2 291 PRINTS PR00599 Methionine aminopeptidase-1 signature 146 158 1.2E-17 T 01-11-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 AFULGI_00020960 0f227c23b9207a0445523666869831b2 291 PRINTS PR00599 Methionine aminopeptidase-1 signature 80 96 1.2E-17 T 01-11-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 AFULGI_00020960 0f227c23b9207a0445523666869831b2 291 Gene3D G3DSA:1.10.10.10 196 267 3.4E-93 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00020960 0f227c23b9207a0445523666869831b2 291 SUPERFAMILY SSF55920 2 290 8.77E-65 T 01-11-2018 IPR036005 Creatinase/aminopeptidase-like AFULGI_00020960 0f227c23b9207a0445523666869831b2 291 Gene3D G3DSA:3.90.230.10 11 281 3.4E-93 T 01-11-2018 AFULGI_00020960 0f227c23b9207a0445523666869831b2 291 ProSitePatterns PS01202 Methionine aminopeptidase subfamily 2 signature. 80 96 - T 01-11-2018 IPR018349 Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site MetaCyc: PWY-7799|MetaCyc: PWY-7800 AFULGI_00020960 0f227c23b9207a0445523666869831b2 291 Pfam PF00557 Metallopeptidase family M24 8 282 3.7E-46 T 01-11-2018 IPR000994 Peptidase M24 AFULGI_00020960 0f227c23b9207a0445523666869831b2 291 TIGRFAM TIGR00501 met_pdase_II: methionine aminopeptidase, type II 2 291 7.8E-142 T 01-11-2018 IPR002468 Peptidase M24A, methionine aminopeptidase, subfamily 2 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800|Reactome: R-HSA-2514859 AFULGI_00013160 36cd6a29ca64c21b3022b19239def69e 331 SUPERFAMILY SSF102114 21 254 6.8E-22 T 01-11-2018 AFULGI_00013160 36cd6a29ca64c21b3022b19239def69e 331 Pfam PF04055 Radical SAM superfamily 30 125 8.0E-13 T 01-11-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFULGI_00013160 36cd6a29ca64c21b3022b19239def69e 331 Pfam PF13353 4Fe-4S single cluster domain 22 104 3.1E-6 T 01-11-2018 AFULGI_00013160 36cd6a29ca64c21b3022b19239def69e 331 Gene3D G3DSA:3.20.20.70 18 308 2.5E-13 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFULGI_00008770 0daaf5604cde58e0f8fa02049e38517d 289 Gene3D G3DSA:3.40.50.300 16 271 3.0E-35 T 01-11-2018 AFULGI_00008770 0daaf5604cde58e0f8fa02049e38517d 289 SUPERFAMILY SSF52540 46 265 6.23E-25 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00008770 0daaf5604cde58e0f8fa02049e38517d 289 TIGRFAM TIGR03878 thermo_KaiC_2: KaiC domain protein, AF_0795 family 17 274 1.2E-128 T 01-11-2018 IPR022373 KaiC domain-containing protein AFULGI_00008770 0daaf5604cde58e0f8fa02049e38517d 289 Pfam PF06745 KaiC 20 272 5.8E-72 T 01-11-2018 IPR014774 KaiC-like domain AFULGI_00004910 e94fe39847efac6febbf17696fcc4283 71 SUPERFAMILY SSF57783 3 48 1.79E-6 T 01-11-2018 AFULGI_00004260 0d61e165ef65a017061a87efb682e45b 243 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 8 22 - T 01-11-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 AFULGI_00004260 0d61e165ef65a017061a87efb682e45b 243 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 4 210 1.2E-49 T 01-11-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 AFULGI_00004260 0d61e165ef65a017061a87efb682e45b 243 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 3 231 1.3E-70 T 01-11-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0008168|GO:0019354 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 AFULGI_00004260 0d61e165ef65a017061a87efb682e45b 243 SUPERFAMILY SSF53790 3 231 4.45E-63 T 01-11-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 AFULGI_00004260 0d61e165ef65a017061a87efb682e45b 243 Gene3D G3DSA:3.40.1010.10 1 120 4.0E-41 T 01-11-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 AFULGI_00004260 0d61e165ef65a017061a87efb682e45b 243 Gene3D G3DSA:3.30.950.10 121 240 1.0E-26 T 01-11-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 AFULGI_00025300 ced54331347e61b52ee351df7807b0da 181 SUPERFAMILY SSF52972 2 178 7.06E-60 T 01-11-2018 IPR029001 Inosine triphosphate pyrophosphatase-like AFULGI_00025300 ced54331347e61b52ee351df7807b0da 181 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 1 176 1.3E-72 T 01-11-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 AFULGI_00025300 ced54331347e61b52ee351df7807b0da 181 Hamap MF_01405 dITP/XTP pyrophosphatase. 1 178 40.79 T 01-11-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 KEGG: 00230+3.6.1.66 AFULGI_00025300 ced54331347e61b52ee351df7807b0da 181 Gene3D G3DSA:3.90.950.10 1 181 1.7E-66 T 01-11-2018 IPR029001 Inosine triphosphate pyrophosphatase-like AFULGI_00025300 ced54331347e61b52ee351df7807b0da 181 Pfam PF01725 Ham1 family 2 175 3.8E-51 T 01-11-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 AFULGI_00018020 3265ea7fe084afd2cb168c8beeea6354 174 Gene3D G3DSA:1.10.150.20 118 174 4.4E-36 T 01-11-2018 AFULGI_00018020 3265ea7fe084afd2cb168c8beeea6354 174 Gene3D G3DSA:3.40.1350.10 1 117 6.0E-43 T 01-11-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 AFULGI_00018020 3265ea7fe084afd2cb168c8beeea6354 174 SUPERFAMILY SSF47794 118 174 5.89E-31 T 01-11-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 AFULGI_00018020 3265ea7fe084afd2cb168c8beeea6354 174 Pfam PF04471 Restriction endonuclease 1 92 4.7E-8 T 01-11-2018 IPR007560 Restriction endonuclease type IV, Mrr GO:0003677|GO:0004519|GO:0009307 AFULGI_00018020 3265ea7fe084afd2cb168c8beeea6354 174 SUPERFAMILY SSF52980 1 110 4.51E-29 T 01-11-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 AFULGI_00000410 2b5fa02a8215aeb2a1b433ecb0baa5f8 307 ProSitePatterns PS00018 EF-hand calcium-binding domain. 249 261 - T 01-11-2018 IPR018247 EF-Hand 1, calcium-binding site AFULGI_00000410 2b5fa02a8215aeb2a1b433ecb0baa5f8 307 Pfam PF00801 PKD domain 158 217 2.3E-8 T 01-11-2018 IPR000601 PKD domain AFULGI_00000410 2b5fa02a8215aeb2a1b433ecb0baa5f8 307 Gene3D G3DSA:2.60.40.10 146 228 6.3E-20 T 01-11-2018 IPR013783 Immunoglobulin-like fold AFULGI_00000410 2b5fa02a8215aeb2a1b433ecb0baa5f8 307 SMART SM00089 151 228 2.2E-13 T 01-11-2018 IPR022409 PKD/Chitinase domain AFULGI_00000410 2b5fa02a8215aeb2a1b433ecb0baa5f8 307 Gene3D G3DSA:1.10.1330.10 244 302 1.2E-6 T 01-11-2018 AFULGI_00000410 2b5fa02a8215aeb2a1b433ecb0baa5f8 307 SUPERFAMILY SSF63446 246 299 1.65E-6 T 01-11-2018 IPR036439 Dockerin domain superfamily GO:0000272 AFULGI_00000410 2b5fa02a8215aeb2a1b433ecb0baa5f8 307 SUPERFAMILY SSF49299 148 227 1.22E-15 T 01-11-2018 IPR035986 PKD domain superfamily AFULGI_00002390 756ace707f73a15204829f58ca222f7c 532 Pfam PF06418 CTP synthase N-terminus 2 265 2.5E-125 T 01-11-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 AFULGI_00002390 756ace707f73a15204829f58ca222f7c 532 TIGRFAM TIGR00337 PyrG: CTP synthase 1 522 2.0E-260 T 01-11-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 AFULGI_00002390 756ace707f73a15204829f58ca222f7c 532 Gene3D G3DSA:3.40.50.880 284 532 3.4E-108 T 01-11-2018 IPR029062 Class I glutamine amidotransferase-like AFULGI_00002390 756ace707f73a15204829f58ca222f7c 532 SUPERFAMILY SSF52317 287 529 4.14E-83 T 01-11-2018 IPR029062 Class I glutamine amidotransferase-like AFULGI_00002390 756ace707f73a15204829f58ca222f7c 532 Pfam PF00117 Glutamine amidotransferase class-I 299 521 5.3E-62 T 01-11-2018 IPR017926 Glutamine amidotransferase AFULGI_00002390 756ace707f73a15204829f58ca222f7c 532 SUPERFAMILY SSF52540 1 265 4.11E-116 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00002390 756ace707f73a15204829f58ca222f7c 532 Hamap MF_01227 CTP synthase [pyrG]. 1 527 51.43 T 01-11-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 AFULGI_00002390 756ace707f73a15204829f58ca222f7c 532 Gene3D G3DSA:3.40.50.300 1 283 1.6E-136 T 01-11-2018 AFULGI_00005110 72e512c3b1da242584ab42eca68b1340 332 SUPERFAMILY SSF103501 2 278 8.5E-51 T 01-11-2018 IPR036197 NarG-like superfamily AFULGI_00005110 72e512c3b1da242584ab42eca68b1340 332 Gene3D G3DSA:1.20.950.20 73 263 1.9E-20 T 01-11-2018 AFULGI_00005110 72e512c3b1da242584ab42eca68b1340 332 Pfam PF02665 Nitrate reductase gamma subunit 98 256 5.3E-16 T 01-11-2018 IPR023234 NarG-like domain AFULGI_00018670 ef319854f5c33535a839a98b63374c22 80 Pfam PF17373 Family of unknown function (DUF5395) 3 79 5.4E-32 T 01-11-2018 IPR035157 Protein of unknown function DUF5395 AFULGI_00018670 ef319854f5c33535a839a98b63374c22 80 ProDom PD750419 PRECURSOR SIGNAL AF1616 11 79 3.0E-25 T 01-11-2018 IPR035157 Protein of unknown function DUF5395 AFULGI_00019890 91ce6a9c01e552a405e7060964d44f67 404 SUPERFAMILY SSF51905 1 399 9.71E-28 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFULGI_00019890 91ce6a9c01e552a405e7060964d44f67 404 Pfam PF01593 Flavin containing amine oxidoreductase 10 399 1.7E-33 T 01-11-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 AFULGI_00019890 91ce6a9c01e552a405e7060964d44f67 404 Gene3D G3DSA:3.50.50.60 1 403 5.0E-25 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFULGI_00004280 cb9e0e2c38857cc42d31283eed7a4430 366 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 241 252 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFULGI_00004280 cb9e0e2c38857cc42d31283eed7a4430 366 TIGRFAM TIGR02066 dsrB: sulfite reductase, dissimilatory-type beta subunit 22 366 2.8E-187 T 01-11-2018 IPR011808 Sulphite reductase, dissimilatory-type beta subunit GO:0006790|GO:0009055|GO:0018551|GO:0051539 KEGG: 00633+1.8.99.5|KEGG: 00920+1.8.99.5|MetaCyc: PWY-5306|MetaCyc: PWY-5360 AFULGI_00004280 cb9e0e2c38857cc42d31283eed7a4430 366 SUPERFAMILY SSF54862 210 252 6.75E-10 T 01-11-2018 AFULGI_00004280 cb9e0e2c38857cc42d31283eed7a4430 366 SUPERFAMILY SSF55124 4 122 1.07E-45 T 01-11-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AFULGI_00004280 cb9e0e2c38857cc42d31283eed7a4430 366 SUPERFAMILY SSF56014 128 357 2.09E-45 T 01-11-2018 AFULGI_00004280 cb9e0e2c38857cc42d31283eed7a4430 366 Gene3D G3DSA:3.30.413.10 130 350 3.6E-108 T 01-11-2018 AFULGI_00004280 cb9e0e2c38857cc42d31283eed7a4430 366 Gene3D G3DSA:3.30.70.3340 1 116 4.2E-54 T 01-11-2018 AFULGI_00004280 cb9e0e2c38857cc42d31283eed7a4430 366 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 46 109 1.8E-11 T 01-11-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AFULGI_00004280 cb9e0e2c38857cc42d31283eed7a4430 366 Pfam PF00037 4Fe-4S binding domain 234 252 4.2E-5 T 01-11-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFULGI_00004280 cb9e0e2c38857cc42d31283eed7a4430 366 Gene3D G3DSA:3.30.70.20 198 256 3.6E-108 T 01-11-2018 AFULGI_00004280 cb9e0e2c38857cc42d31283eed7a4430 366 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 128 343 1.5E-39 T 01-11-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AFULGI_00009710 d5db57bc38522462208b1f8c34fdf777 483 Pfam PF14698 Argininosuccinate lyase C-terminal 355 425 8.9E-17 T 01-11-2018 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 AFULGI_00009710 d5db57bc38522462208b1f8c34fdf777 483 PRINTS PR00149 Fumarate lyase superfamily signature 140 158 4.7E-22 T 01-11-2018 IPR000362 Fumarate lyase family AFULGI_00009710 d5db57bc38522462208b1f8c34fdf777 483 PRINTS PR00149 Fumarate lyase superfamily signature 224 251 4.7E-22 T 01-11-2018 IPR000362 Fumarate lyase family AFULGI_00009710 d5db57bc38522462208b1f8c34fdf777 483 PRINTS PR00149 Fumarate lyase superfamily signature 267 283 4.7E-22 T 01-11-2018 IPR000362 Fumarate lyase family AFULGI_00009710 d5db57bc38522462208b1f8c34fdf777 483 PRINTS PR00149 Fumarate lyase superfamily signature 96 114 4.7E-22 T 01-11-2018 IPR000362 Fumarate lyase family AFULGI_00009710 d5db57bc38522462208b1f8c34fdf777 483 PRINTS PR00145 Argininosuccinate lyase family signature 95 117 5.1E-46 T 01-11-2018 AFULGI_00009710 d5db57bc38522462208b1f8c34fdf777 483 PRINTS PR00145 Argininosuccinate lyase family signature 186 202 5.1E-46 T 01-11-2018 AFULGI_00009710 d5db57bc38522462208b1f8c34fdf777 483 PRINTS PR00145 Argininosuccinate lyase family signature 267 283 5.1E-46 T 01-11-2018 AFULGI_00009710 d5db57bc38522462208b1f8c34fdf777 483 PRINTS PR00145 Argininosuccinate lyase family signature 302 321 5.1E-46 T 01-11-2018 AFULGI_00009710 d5db57bc38522462208b1f8c34fdf777 483 PRINTS PR00145 Argininosuccinate lyase family signature 224 248 5.1E-46 T 01-11-2018 AFULGI_00009710 d5db57bc38522462208b1f8c34fdf777 483 PRINTS PR00145 Argininosuccinate lyase family signature 135 155 5.1E-46 T 01-11-2018 AFULGI_00009710 d5db57bc38522462208b1f8c34fdf777 483 Gene3D G3DSA:1.10.275.10 27 222 4.5E-142 T 01-11-2018 IPR024083 Fumarase/histidase, N-terminal AFULGI_00009710 d5db57bc38522462208b1f8c34fdf777 483 TIGRFAM TIGR00838 argH: argininosuccinate lyase 2 449 6.7E-185 T 01-11-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 AFULGI_00009710 d5db57bc38522462208b1f8c34fdf777 483 Hamap MF_00006 Argininosuccinate lyase [argH]. 1 447 38.632 T 01-11-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 AFULGI_00009710 d5db57bc38522462208b1f8c34fdf777 483 Gene3D G3DSA:1.10.40.30 352 426 4.5E-142 T 01-11-2018 AFULGI_00009710 d5db57bc38522462208b1f8c34fdf777 483 Gene3D G3DSA:1.20.200.10 113 442 4.5E-142 T 01-11-2018 AFULGI_00009710 d5db57bc38522462208b1f8c34fdf777 483 Pfam PF00206 Lyase 32 292 3.4E-51 T 01-11-2018 IPR022761 Fumarate lyase, N-terminal AFULGI_00009710 d5db57bc38522462208b1f8c34fdf777 483 SUPERFAMILY SSF48557 6 451 2.04E-111 T 01-11-2018 IPR008948 L-Aspartase-like GO:0003824 AFULGI_00025680 36b80c09593e873a3596e9b3cb09f899 255 SUPERFAMILY SSF46785 9 110 1.46E-18 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00025680 36b80c09593e873a3596e9b3cb09f899 255 SMART SM00418 2 86 1.7E-4 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFULGI_00025680 36b80c09593e873a3596e9b3cb09f899 255 Gene3D G3DSA:1.10.10.10 1 72 1.7E-12 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00025680 36b80c09593e873a3596e9b3cb09f899 255 PIRSF PIRSF006692 1 255 6.4E-72 T 01-11-2018 IPR016490 Transcriptional regulator, HTH, AF0396-type AFULGI_00025680 36b80c09593e873a3596e9b3cb09f899 255 Pfam PF08350 Domain of unknown function (DUF1724) 197 250 4.6E-15 T 01-11-2018 IPR013561 Domain of unknown function DUF1724 AFULGI_00025680 36b80c09593e873a3596e9b3cb09f899 255 SMART SM00419 16 65 6.5E-10 T 01-11-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 AFULGI_00025680 36b80c09593e873a3596e9b3cb09f899 255 Pfam PF01022 Bacterial regulatory protein, arsR family 12 56 1.3E-14 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFULGI_00006040 e736a673a2abfeffa62461baf3940d85 232 SUPERFAMILY SSF53271 88 223 2.75E-18 T 01-11-2018 IPR029057 Phosphoribosyltransferase-like AFULGI_00006040 e736a673a2abfeffa62461baf3940d85 232 Gene3D G3DSA:3.40.50.2020 95 229 3.6E-15 T 01-11-2018 AFULGI_00006040 e736a673a2abfeffa62461baf3940d85 232 Pfam PF00156 Phosphoribosyl transferase domain 132 224 3.7E-9 T 01-11-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 AFULGI_00001570 1e179e4184bf904408f2db2776879cf5 1134 Gene3D G3DSA:3.40.50.740 597 725 2.4E-12 T 01-11-2018 AFULGI_00001570 1e179e4184bf904408f2db2776879cf5 1134 SUPERFAMILY SSF50692 925 1017 2.07E-22 T 01-11-2018 IPR009010 Aspartate decarboxylase-like domain superfamily AFULGI_00001570 1e179e4184bf904408f2db2776879cf5 1134 Gene3D G3DSA:2.40.40.20 898 1042 9.4E-20 T 01-11-2018 AFULGI_00001570 1e179e4184bf904408f2db2776879cf5 1134 SUPERFAMILY SSF53706 47 931 1.48E-112 T 01-11-2018 AFULGI_00001570 1e179e4184bf904408f2db2776879cf5 1134 Pfam PF00384 Molybdopterin oxidoreductase 321 710 4.7E-16 T 01-11-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFULGI_00001570 1e179e4184bf904408f2db2776879cf5 1134 Pfam PF01568 Molydopterin dinucleotide binding domain 951 1011 9.1E-13 T 01-11-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 AFULGI_00001570 1e179e4184bf904408f2db2776879cf5 1134 Gene3D G3DSA:3.40.50.740 38 202 2.3E-15 T 01-11-2018 AFULGI_00001570 1e179e4184bf904408f2db2776879cf5 1134 SMART SM00926 46 131 1.5E-13 T 01-11-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFULGI_00023600 533a6baeee26689da05b1167ffa56701 245 Gene3D G3DSA:3.40.50.10670 131 226 1.4E-46 T 01-11-2018 AFULGI_00023600 533a6baeee26689da05b1167ffa56701 245 Gene3D G3DSA:1.10.3400.10 1 130 3.3E-68 T 01-11-2018 IPR023291 Af2093, N-terminal AFULGI_00026990 1a244fdcd9d5fa50573fcc2e6a733270 88 SUPERFAMILY SSF143430 2 81 1.44E-24 T 01-11-2018 AFULGI_00026990 1a244fdcd9d5fa50573fcc2e6a733270 88 Gene3D G3DSA:3.30.70.240 1 66 4.1E-28 T 01-11-2018 AFULGI_00026990 1a244fdcd9d5fa50573fcc2e6a733270 88 Pfam PF09827 CRISPR associated protein Cas2 2 71 2.7E-20 T 01-11-2018 IPR019199 Virulence-associated protein D / CRISPR associated protein Cas2 AFULGI_00026990 1a244fdcd9d5fa50573fcc2e6a733270 88 Hamap MF_01471 CRISPR-associated endoribonuclease Cas2 [cas2]. 1 88 16.035 T 01-11-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 AFULGI_00026990 1a244fdcd9d5fa50573fcc2e6a733270 88 TIGRFAM TIGR01573 cas2: CRISPR-associated endonuclease Cas2 2 77 4.9E-12 T 01-11-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 AFULGI_00020030 c876f911f784403e272c019a8c31d3bf 486 TIGRFAM TIGR01312 XylB: xylulokinase 4 479 6.9E-115 T 01-11-2018 IPR006000 Xylulokinase GO:0004856|GO:0005997 KEGG: 00040+2.7.1.17 AFULGI_00020030 c876f911f784403e272c019a8c31d3bf 486 SUPERFAMILY SSF53067 247 482 5.8E-61 T 01-11-2018 AFULGI_00020030 c876f911f784403e272c019a8c31d3bf 486 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 4 244 1.3E-71 T 01-11-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 AFULGI_00020030 c876f911f784403e272c019a8c31d3bf 486 PIRSF PIRSF000538 1 485 7.1E-144 T 01-11-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 AFULGI_00020030 c876f911f784403e272c019a8c31d3bf 486 Gene3D G3DSA:3.30.420.40 242 485 4.6E-70 T 01-11-2018 AFULGI_00020030 c876f911f784403e272c019a8c31d3bf 486 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 255 437 1.3E-35 T 01-11-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 AFULGI_00020030 c876f911f784403e272c019a8c31d3bf 486 Gene3D G3DSA:3.30.420.40 2 241 1.7E-91 T 01-11-2018 AFULGI_00020030 c876f911f784403e272c019a8c31d3bf 486 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 351 371 - T 01-11-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 AFULGI_00020030 c876f911f784403e272c019a8c31d3bf 486 SUPERFAMILY SSF53067 2 248 2.31E-83 T 01-11-2018 AFULGI_00013970 38567efaa553c36b8ade024cd79bf0da 559 Gene3D G3DSA:3.20.20.240 1 559 1.2E-255 T 01-11-2018 AFULGI_00013970 38567efaa553c36b8ade024cd79bf0da 559 SUPERFAMILY SSF51703 4 553 4.97E-218 T 01-11-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 AFULGI_00013970 38567efaa553c36b8ade024cd79bf0da 559 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 30 557 3.4E-244 T 01-11-2018 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 AFULGI_00013970 38567efaa553c36b8ade024cd79bf0da 559 Pfam PF01642 Methylmalonyl-CoA mutase 32 551 8.6E-227 T 01-11-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 AFULGI_00019970 42c129e0c0867aa9edc15115390b0f86 468 Pfam PF00909 Ammonium Transporter Family 40 448 4.4E-140 T 01-11-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 AFULGI_00019970 42c129e0c0867aa9edc15115390b0f86 468 Gene3D G3DSA:1.10.3430.10 17 459 5.4E-146 T 01-11-2018 IPR029020 Ammonium/urea transporter AFULGI_00019970 42c129e0c0867aa9edc15115390b0f86 468 TIGRFAM TIGR00836 amt: ammonium transporter 38 448 3.7E-147 T 01-11-2018 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 AFULGI_00019970 42c129e0c0867aa9edc15115390b0f86 468 SUPERFAMILY SSF111352 37 429 7.19E-115 T 01-11-2018 AFULGI_00019970 42c129e0c0867aa9edc15115390b0f86 468 PRINTS PR00342 Rhesus blood group protein signature 237 255 5.9E-10 T 01-11-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 AFULGI_00019970 42c129e0c0867aa9edc15115390b0f86 468 PRINTS PR00342 Rhesus blood group protein signature 142 158 5.9E-10 T 01-11-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 AFULGI_00019970 42c129e0c0867aa9edc15115390b0f86 468 PRINTS PR00342 Rhesus blood group protein signature 324 342 5.9E-10 T 01-11-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 AFULGI_00019970 42c129e0c0867aa9edc15115390b0f86 468 PRINTS PR00342 Rhesus blood group protein signature 200 215 5.9E-10 T 01-11-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 AFULGI_00019970 42c129e0c0867aa9edc15115390b0f86 468 ProSitePatterns PS01219 Ammonium transporters signature. 193 218 - T 01-11-2018 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 AFULGI_00025360 f7c2466c93a85380f64d0af5f095665b 414 Pfam PF02803 Thiolase, C-terminal domain 290 410 2.8E-43 T 01-11-2018 IPR020617 Thiolase, C-terminal GO:0016747 AFULGI_00025360 f7c2466c93a85380f64d0af5f095665b 414 PIRSF PIRSF000429 1 413 8.9E-113 T 01-11-2018 IPR002155 Thiolase GO:0016747 AFULGI_00025360 f7c2466c93a85380f64d0af5f095665b 414 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 410 7.3E-118 T 01-11-2018 IPR002155 Thiolase GO:0016747 AFULGI_00025360 f7c2466c93a85380f64d0af5f095665b 414 ProSitePatterns PS00737 Thiolases signature 2. 358 374 - T 01-11-2018 IPR020613 Thiolase, conserved site GO:0016747 AFULGI_00025360 f7c2466c93a85380f64d0af5f095665b 414 Pfam PF00108 Thiolase, N-terminal domain 4 281 3.2E-54 T 01-11-2018 IPR020616 Thiolase, N-terminal GO:0016747 AFULGI_00025360 f7c2466c93a85380f64d0af5f095665b 414 SUPERFAMILY SSF53901 290 410 1.44E-39 T 01-11-2018 IPR016039 Thiolase-like GO:0003824 AFULGI_00025360 f7c2466c93a85380f64d0af5f095665b 414 Gene3D G3DSA:3.40.47.10 1 412 1.1E-119 T 01-11-2018 IPR016039 Thiolase-like GO:0003824 AFULGI_00025360 f7c2466c93a85380f64d0af5f095665b 414 SUPERFAMILY SSF53901 1 287 3.4E-54 T 01-11-2018 IPR016039 Thiolase-like GO:0003824 AFULGI_00009220 6b859b38b87b3f36960d90187d87c8af 436 Gene3D G3DSA:3.40.50.720 2 133 2.7E-39 T 01-11-2018 AFULGI_00009220 6b859b38b87b3f36960d90187d87c8af 436 Pfam PF02080 TrkA-C domain 369 435 1.4E-17 T 01-11-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 AFULGI_00009220 6b859b38b87b3f36960d90187d87c8af 436 Pfam PF02080 TrkA-C domain 150 218 1.4E-16 T 01-11-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 AFULGI_00009220 6b859b38b87b3f36960d90187d87c8af 436 Pfam PF02254 TrkA-N domain 226 341 8.5E-23 T 01-11-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 AFULGI_00009220 6b859b38b87b3f36960d90187d87c8af 436 Pfam PF02254 TrkA-N domain 3 103 2.0E-24 T 01-11-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 AFULGI_00009220 6b859b38b87b3f36960d90187d87c8af 436 Gene3D G3DSA:3.40.50.720 223 356 3.4E-33 T 01-11-2018 AFULGI_00009220 6b859b38b87b3f36960d90187d87c8af 436 SUPERFAMILY SSF116726 365 435 2.09E-15 T 01-11-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 AFULGI_00009220 6b859b38b87b3f36960d90187d87c8af 436 Gene3D G3DSA:3.30.70.1450 135 219 4.6E-22 T 01-11-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 AFULGI_00009220 6b859b38b87b3f36960d90187d87c8af 436 PRINTS PR00335 TrkA potassium uptake protein signature 18 32 2.9E-14 T 01-11-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 AFULGI_00009220 6b859b38b87b3f36960d90187d87c8af 436 PRINTS PR00335 TrkA potassium uptake protein signature 2 16 2.9E-14 T 01-11-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 AFULGI_00009220 6b859b38b87b3f36960d90187d87c8af 436 PRINTS PR00335 TrkA potassium uptake protein signature 58 68 2.9E-14 T 01-11-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 AFULGI_00009220 6b859b38b87b3f36960d90187d87c8af 436 PRINTS PR00335 TrkA potassium uptake protein signature 47 57 2.9E-14 T 01-11-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 AFULGI_00009220 6b859b38b87b3f36960d90187d87c8af 436 PRINTS PR00335 TrkA potassium uptake protein signature 71 85 2.9E-14 T 01-11-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 AFULGI_00009220 6b859b38b87b3f36960d90187d87c8af 436 SUPERFAMILY SSF51735 222 364 7.46E-28 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily AFULGI_00009220 6b859b38b87b3f36960d90187d87c8af 436 Gene3D G3DSA:3.30.70.1450 357 436 1.8E-21 T 01-11-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 AFULGI_00009220 6b859b38b87b3f36960d90187d87c8af 436 SUPERFAMILY SSF51735 1 147 1.24E-32 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily AFULGI_00009220 6b859b38b87b3f36960d90187d87c8af 436 SUPERFAMILY SSF116726 131 218 3.14E-18 T 01-11-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 AFULGI_00019870 76be79f086d240ecffac982b264166f3 417 Gene3D G3DSA:3.90.770.10 12 362 4.2E-134 T 01-11-2018 IPR023074 Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain superfamily GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 AFULGI_00019870 76be79f086d240ecffac982b264166f3 417 ProSitePatterns PS00066 Hydroxymethylglutaryl-coenzyme A reductases signature 1. 172 186 - T 01-11-2018 IPR023076 Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 AFULGI_00019870 76be79f086d240ecffac982b264166f3 417 Gene3D G3DSA:1.10.8.660 366 417 3.6E-18 T 01-11-2018 AFULGI_00019870 76be79f086d240ecffac982b264166f3 417 SUPERFAMILY SSF55035 108 214 6.41E-33 T 01-11-2018 IPR009023 Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain superfamily GO:0050662 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 AFULGI_00019870 76be79f086d240ecffac982b264166f3 417 SUPERFAMILY SSF56542 4 416 1.57E-106 T 01-11-2018 IPR009029 Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domain superfamily GO:0015936|GO:0016616|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 AFULGI_00019870 76be79f086d240ecffac982b264166f3 417 Pfam PF00368 Hydroxymethylglutaryl-coenzyme A reductase 12 376 6.9E-116 T 01-11-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 AFULGI_00019870 76be79f086d240ecffac982b264166f3 417 Gene3D G3DSA:3.30.70.420 107 216 4.2E-134 T 01-11-2018 IPR009023 Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain superfamily GO:0050662 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 AFULGI_00019870 76be79f086d240ecffac982b264166f3 417 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 47 68 3.3E-8 T 01-11-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 AFULGI_00019870 76be79f086d240ecffac982b264166f3 417 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 170 188 3.3E-8 T 01-11-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 AFULGI_00019870 76be79f086d240ecffac982b264166f3 417 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 303 324 3.3E-8 T 01-11-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 AFULGI_00019870 76be79f086d240ecffac982b264166f3 417 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 74 94 3.3E-8 T 01-11-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 AFULGI_00019870 76be79f086d240ecffac982b264166f3 417 ProSitePatterns PS00318 Hydroxymethylglutaryl-coenzyme A reductases signature 2. 315 322 - T 01-11-2018 IPR023076 Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 AFULGI_00019870 76be79f086d240ecffac982b264166f3 417 ProSitePatterns PS01192 Hydroxymethylglutaryl-coenzyme A reductases signature 3. 361 374 - T 01-11-2018 IPR023076 Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 AFULGI_00019870 76be79f086d240ecffac982b264166f3 417 TIGRFAM TIGR00532 HMG_CoA_R_NAD: hydroxymethylglutaryl-CoA reductase, degradative 1 376 2.8E-219 T 01-11-2018 IPR004553 Hydroxymethylglutaryl-CoA reductase, bacterial-type GO:0015936|GO:0016616|GO:0050662 AFULGI_00000640 6317fd4705be6c29d18290e6e35e50f8 759 SMART SM00487 10 219 2.5E-24 T 01-11-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFULGI_00000640 6317fd4705be6c29d18290e6e35e50f8 759 SMART SM00490 254 339 1.8E-9 T 01-11-2018 IPR001650 Helicase, C-terminal AFULGI_00000640 6317fd4705be6c29d18290e6e35e50f8 759 TIGRFAM TIGR01596 cas3_HD: CRISPR-associated endonuclease Cas3-HD 563 748 1.0E-22 T 01-11-2018 IPR006483 CRISPR-associated Cas3-type HD domain AFULGI_00000640 6317fd4705be6c29d18290e6e35e50f8 759 Gene3D G3DSA:3.40.50.300 210 453 2.4E-14 T 01-11-2018 AFULGI_00000640 6317fd4705be6c29d18290e6e35e50f8 759 Pfam PF01966 HD domain 582 748 2.4E-15 T 01-11-2018 IPR006674 HD domain AFULGI_00000640 6317fd4705be6c29d18290e6e35e50f8 759 TIGRFAM TIGR01587 cas3_core: CRISPR-associated helicase Cas3 31 373 2.4E-58 T 01-11-2018 IPR006474 Helicase Cas3, CRISPR-associated, core AFULGI_00000640 6317fd4705be6c29d18290e6e35e50f8 759 Gene3D G3DSA:1.10.3210.30 550 737 4.5E-16 T 01-11-2018 IPR038257 CRISPR-associated Cas3-type HD domain superfamily AFULGI_00000640 6317fd4705be6c29d18290e6e35e50f8 759 Pfam PF00271 Helicase conserved C-terminal domain 233 338 1.1E-8 T 01-11-2018 IPR001650 Helicase, C-terminal AFULGI_00000640 6317fd4705be6c29d18290e6e35e50f8 759 SUPERFAMILY SSF52540 24 347 2.94E-29 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00000640 6317fd4705be6c29d18290e6e35e50f8 759 Gene3D G3DSA:3.40.50.300 2 200 3.4E-24 T 01-11-2018 AFULGI_00000640 6317fd4705be6c29d18290e6e35e50f8 759 Pfam PF00270 DEAD/DEAH box helicase 16 182 1.4E-18 T 01-11-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 AFULGI_00014330 5782bd1cbf38fbd73571e0230570b4e5 501 Pfam PF13180 PDZ domain 287 345 1.6E-9 T 01-11-2018 IPR001478 PDZ domain GO:0005515 AFULGI_00014330 5782bd1cbf38fbd73571e0230570b4e5 501 Pfam PF02163 Peptidase family M50 125 483 1.2E-21 T 01-11-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 AFULGI_00014330 5782bd1cbf38fbd73571e0230570b4e5 501 Gene3D G3DSA:2.30.42.10 265 351 6.1E-13 T 01-11-2018 AFULGI_00014330 5782bd1cbf38fbd73571e0230570b4e5 501 PRINTS PR01000 Sterol regulatory element binding protein site 2 protease (M50) signature 132 146 9.1E-14 T 01-11-2018 IPR001193 Membrane-bound transcription factor site-2 protease GO:0004222|GO:0006508|GO:0016020 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 AFULGI_00014330 5782bd1cbf38fbd73571e0230570b4e5 501 PRINTS PR01000 Sterol regulatory element binding protein site 2 protease (M50) signature 110 129 9.1E-14 T 01-11-2018 IPR001193 Membrane-bound transcription factor site-2 protease GO:0004222|GO:0006508|GO:0016020 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 AFULGI_00014330 5782bd1cbf38fbd73571e0230570b4e5 501 PRINTS PR01000 Sterol regulatory element binding protein site 2 protease (M50) signature 148 163 9.1E-14 T 01-11-2018 IPR001193 Membrane-bound transcription factor site-2 protease GO:0004222|GO:0006508|GO:0016020 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 AFULGI_00014330 5782bd1cbf38fbd73571e0230570b4e5 501 PRINTS PR01000 Sterol regulatory element binding protein site 2 protease (M50) signature 164 176 9.1E-14 T 01-11-2018 IPR001193 Membrane-bound transcription factor site-2 protease GO:0004222|GO:0006508|GO:0016020 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 AFULGI_00014330 5782bd1cbf38fbd73571e0230570b4e5 501 SUPERFAMILY SSF50156 288 363 1.0E-12 T 01-11-2018 IPR036034 PDZ superfamily GO:0005515 AFULGI_00001500 da9f9f79f0345aa0913c0d1a4d7319d1 690 Gene3D G3DSA:3.40.50.1000 381 631 4.0E-107 T 01-11-2018 IPR023214 HAD superfamily AFULGI_00001500 da9f9f79f0345aa0913c0d1a4d7319d1 690 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 108 690 1.5E-205 T 01-11-2018 AFULGI_00001500 da9f9f79f0345aa0913c0d1a4d7319d1 690 SUPERFAMILY SSF81665 125 656 3.66E-11 T 01-11-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 AFULGI_00001500 da9f9f79f0345aa0913c0d1a4d7319d1 690 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 155 687 2.2E-122 T 01-11-2018 AFULGI_00001500 da9f9f79f0345aa0913c0d1a4d7319d1 690 Gene3D G3DSA:2.70.150.20 180 292 2.6E-40 T 01-11-2018 AFULGI_00001500 da9f9f79f0345aa0913c0d1a4d7319d1 690 Gene3D G3DSA:3.40.1110.10 398 514 4.0E-107 T 01-11-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 AFULGI_00001500 da9f9f79f0345aa0913c0d1a4d7319d1 690 Pfam PF00702 haloacid dehalogenase-like hydrolase 384 595 3.8E-47 T 01-11-2018 AFULGI_00001500 da9f9f79f0345aa0913c0d1a4d7319d1 690 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 126 688 1.1E-199 T 01-11-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 AFULGI_00001500 da9f9f79f0345aa0913c0d1a4d7319d1 690 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 163 663 3.2E-101 T 01-11-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 AFULGI_00001500 da9f9f79f0345aa0913c0d1a4d7319d1 690 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 389 395 - T 01-11-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 AFULGI_00001500 da9f9f79f0345aa0913c0d1a4d7319d1 690 Pfam PF00122 E1-E2 ATPase 188 366 2.3E-54 T 01-11-2018 AFULGI_00001500 da9f9f79f0345aa0913c0d1a4d7319d1 690 SUPERFAMILY SSF81653 190 287 4.18E-30 T 01-11-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 AFULGI_00001500 da9f9f79f0345aa0913c0d1a4d7319d1 690 SUPERFAMILY SSF56784 386 686 2.64E-63 T 01-11-2018 IPR036412 HAD-like superfamily AFULGI_00001500 da9f9f79f0345aa0913c0d1a4d7319d1 690 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 554 570 2.0E-10 T 01-11-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 AFULGI_00001500 da9f9f79f0345aa0913c0d1a4d7319d1 690 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 581 597 2.0E-10 T 01-11-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 AFULGI_00001500 da9f9f79f0345aa0913c0d1a4d7319d1 690 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 612 637 2.0E-10 T 01-11-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 AFULGI_00001500 da9f9f79f0345aa0913c0d1a4d7319d1 690 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 387 401 3.2E-30 T 01-11-2018 AFULGI_00001500 da9f9f79f0345aa0913c0d1a4d7319d1 690 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 604 616 3.2E-30 T 01-11-2018 AFULGI_00001500 da9f9f79f0345aa0913c0d1a4d7319d1 690 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 237 251 3.2E-30 T 01-11-2018 AFULGI_00001500 da9f9f79f0345aa0913c0d1a4d7319d1 690 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 507 518 3.2E-30 T 01-11-2018 AFULGI_00001500 da9f9f79f0345aa0913c0d1a4d7319d1 690 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 529 539 3.2E-30 T 01-11-2018 AFULGI_00001500 da9f9f79f0345aa0913c0d1a4d7319d1 690 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 581 600 3.2E-30 T 01-11-2018 AFULGI_00017240 db212fb8a6ad017a1a2eef756d879bca 487 SUPERFAMILY SSF52172 1 155 1.29E-26 T 01-11-2018 IPR011006 CheY-like superfamily AFULGI_00017240 db212fb8a6ad017a1a2eef756d879bca 487 SUPERFAMILY SSF55785 127 252 8.03E-28 T 01-11-2018 IPR035965 PAS domain superfamily AFULGI_00017240 db212fb8a6ad017a1a2eef756d879bca 487 SMART SM00388 417 475 9.8E-7 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFULGI_00017240 db212fb8a6ad017a1a2eef756d879bca 487 SMART SM00086 213 254 4.6E-7 T 01-11-2018 IPR001610 PAC motif AFULGI_00017240 db212fb8a6ad017a1a2eef756d879bca 487 Pfam PF00989 PAS fold 141 251 1.1E-13 T 01-11-2018 IPR013767 PAS fold GO:0006355 AFULGI_00017240 db212fb8a6ad017a1a2eef756d879bca 487 Gene3D G3DSA:3.30.450.20 132 257 1.1E-27 T 01-11-2018 AFULGI_00017240 db212fb8a6ad017a1a2eef756d879bca 487 Pfam PF13185 GAF domain 320 399 2.4E-8 T 01-11-2018 IPR003018 GAF domain GO:0005515 AFULGI_00017240 db212fb8a6ad017a1a2eef756d879bca 487 SMART SM00448 1 115 3.1E-18 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFULGI_00017240 db212fb8a6ad017a1a2eef756d879bca 487 Gene3D G3DSA:3.30.450.40 258 409 2.0E-11 T 01-11-2018 IPR029016 GAF-like domain superfamily AFULGI_00017240 db212fb8a6ad017a1a2eef756d879bca 487 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 136 261 1.6E-35 T 01-11-2018 IPR000014 PAS domain AFULGI_00017240 db212fb8a6ad017a1a2eef756d879bca 487 Gene3D G3DSA:3.40.50.2300 1 131 3.7E-22 T 01-11-2018 AFULGI_00017240 db212fb8a6ad017a1a2eef756d879bca 487 Pfam PF00072 Response regulator receiver domain 3 105 3.7E-16 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFULGI_00017240 db212fb8a6ad017a1a2eef756d879bca 487 SMART SM00091 140 206 6.8E-12 T 01-11-2018 IPR000014 PAS domain AFULGI_00017240 db212fb8a6ad017a1a2eef756d879bca 487 SUPERFAMILY SSF55781 247 400 1.83E-14 T 01-11-2018 AFULGI_00011970 92db6977ff3f547e7155e8cc0d15a6ca 802 Hamap MF_01137 Acetyl-CoA decarbonylase/synthase complex subunit alpha [cdhA]. 2 789 45.156 T 01-11-2018 IPR004460 Acetyl-CoA decarbonylase/synthase complex subunit alpha GO:0006084|GO:0055114 KEGG: 00633+1.2.7.4|KEGG: 00680+1.2.7.4|KEGG: 00720+1.2.7.4|MetaCyc: PWY-5372|MetaCyc: PWY-6780|MetaCyc: PWY-7784 AFULGI_00011970 92db6977ff3f547e7155e8cc0d15a6ca 802 SUPERFAMILY SSF56821 14 734 1.56E-165 T 01-11-2018 IPR011254 Prismane-like superfamily GO:0003824|GO:0016491|GO:0055114 AFULGI_00011970 92db6977ff3f547e7155e8cc0d15a6ca 802 Gene3D G3DSA:3.40.50.2030 36 765 0.0 T 01-11-2018 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 AFULGI_00011970 92db6977ff3f547e7155e8cc0d15a6ca 802 Pfam PF03063 Prismane/CO dehydrogenase family 66 123 6.4E-16 T 01-11-2018 IPR004137 Hydroxylamine reductase/Ni-containing CO dehydrogenase GO:0016491|GO:0055114 KEGG: 00910+1.7.99.1 AFULGI_00011970 92db6977ff3f547e7155e8cc0d15a6ca 802 SUPERFAMILY SSF46548 391 467 3.14E-12 T 01-11-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 AFULGI_00011970 92db6977ff3f547e7155e8cc0d15a6ca 802 TIGRFAM TIGR00314 cdhA: CO dehydrogenase/acetyl-CoA synthase complex, epsilon subunit 3 789 0.0 T 01-11-2018 IPR004460 Acetyl-CoA decarbonylase/synthase complex subunit alpha GO:0006084|GO:0055114 KEGG: 00633+1.2.7.4|KEGG: 00680+1.2.7.4|KEGG: 00720+1.2.7.4|MetaCyc: PWY-5372|MetaCyc: PWY-6780|MetaCyc: PWY-7784 AFULGI_00011970 92db6977ff3f547e7155e8cc0d15a6ca 802 Gene3D G3DSA:1.10.1060.10 400 480 0.0 T 01-11-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 AFULGI_00011970 92db6977ff3f547e7155e8cc0d15a6ca 802 Gene3D G3DSA:3.40.50.2030 213 491 0.0 T 01-11-2018 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 AFULGI_00011970 92db6977ff3f547e7155e8cc0d15a6ca 802 Pfam PF03063 Prismane/CO dehydrogenase family 143 681 2.3E-81 T 01-11-2018 IPR004137 Hydroxylamine reductase/Ni-containing CO dehydrogenase GO:0016491|GO:0055114 KEGG: 00910+1.7.99.1 AFULGI_00011970 92db6977ff3f547e7155e8cc0d15a6ca 802 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 444 455 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFULGI_00011970 92db6977ff3f547e7155e8cc0d15a6ca 802 Pfam PF13183 4Fe-4S dicluster domain 402 458 4.2E-7 T 01-11-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFULGI_00005470 81ac2b59947e24971386361ad25f1cd4 157 SUPERFAMILY SSF46906 64 136 6.28E-23 T 01-11-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily AFULGI_00005470 81ac2b59947e24971386361ad25f1cd4 157 Gene3D G3DSA:2.10.260.30 1 67 5.9E-30 T 01-11-2018 AFULGI_00005470 81ac2b59947e24971386361ad25f1cd4 157 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 38 69 0.004 T 01-11-2018 AFULGI_00005470 81ac2b59947e24971386361ad25f1cd4 157 SUPERFAMILY SSF54747 2 80 2.88E-27 T 01-11-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily AFULGI_00005470 81ac2b59947e24971386361ad25f1cd4 157 ProSitePatterns PS00359 Ribosomal protein L11 signature. 122 137 - T 01-11-2018 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00005470 81ac2b59947e24971386361ad25f1cd4 157 Pfam PF00298 Ribosomal protein L11, RNA binding domain 69 135 2.6E-24 T 01-11-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 AFULGI_00005470 81ac2b59947e24971386361ad25f1cd4 157 Pfam PF03946 Ribosomal protein L11, N-terminal domain 5 62 8.6E-26 T 01-11-2018 IPR020784 Ribosomal protein L11, N-terminal AFULGI_00005470 81ac2b59947e24971386361ad25f1cd4 157 Gene3D G3DSA:1.10.10.250 71 156 1.2E-31 T 01-11-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily AFULGI_00005470 81ac2b59947e24971386361ad25f1cd4 157 SMART SM00649 5 136 4.0E-73 T 01-11-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 AFULGI_00005470 81ac2b59947e24971386361ad25f1cd4 157 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 1 137 29.828 T 01-11-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 AFULGI_00002280 1014a72ba25d098a564e711bc44e839b 332 SUPERFAMILY SSF53448 1 279 2.25E-48 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFULGI_00002280 1014a72ba25d098a564e711bc44e839b 332 Gene3D G3DSA:2.160.10.10 240 332 1.0E-6 T 01-11-2018 AFULGI_00002280 1014a72ba25d098a564e711bc44e839b 332 Gene3D G3DSA:3.90.550.10 1 239 1.8E-50 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFULGI_00002280 1014a72ba25d098a564e711bc44e839b 332 Pfam PF00483 Nucleotidyl transferase 2 236 2.7E-48 T 01-11-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 AFULGI_00002280 1014a72ba25d098a564e711bc44e839b 332 SUPERFAMILY SSF51161 237 329 5.42E-11 T 01-11-2018 IPR011004 Trimeric LpxA-like superfamily AFULGI_00011590 7f54e107a7b7f9822c49650b22809277 505 Pfam PF01935 Domain of unknown function DUF87 119 334 1.3E-42 T 01-11-2018 IPR002789 Helicase HerA, central domain AFULGI_00011590 7f54e107a7b7f9822c49650b22809277 505 SUPERFAMILY SSF52540 86 462 1.16E-45 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00011590 7f54e107a7b7f9822c49650b22809277 505 Pfam PF09378 HAS barrel domain 5 84 6.2E-14 T 01-11-2018 IPR018538 Helicase HerA, barrel domain AFULGI_00011590 7f54e107a7b7f9822c49650b22809277 505 Gene3D G3DSA:3.40.50.300 142 207 3.0E-8 T 01-11-2018 AFULGI_00011590 7f54e107a7b7f9822c49650b22809277 505 Gene3D G3DSA:3.40.50.300 245 472 2.1E-49 T 01-11-2018 AFULGI_00004780 80b6cbdc40950abb6c7f94b40a15460d 67 Pfam PF00037 4Fe-4S binding domain 4 25 3.5E-6 T 01-11-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFULGI_00004780 80b6cbdc40950abb6c7f94b40a15460d 67 Pfam PF00037 4Fe-4S binding domain 37 54 1.4E-4 T 01-11-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFULGI_00004780 80b6cbdc40950abb6c7f94b40a15460d 67 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 11 22 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFULGI_00004780 80b6cbdc40950abb6c7f94b40a15460d 67 SUPERFAMILY SSF54862 3 55 3.72E-13 T 01-11-2018 AFULGI_00004780 80b6cbdc40950abb6c7f94b40a15460d 67 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 38 49 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFULGI_00004780 80b6cbdc40950abb6c7f94b40a15460d 67 Gene3D G3DSA:3.30.70.20 6 53 4.6E-9 T 01-11-2018 AFULGI_00001220 849ac42f922da6f6837ca3832ed9fb08 167 Gene3D G3DSA:3.40.50.620 5 147 6.0E-13 T 01-11-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFULGI_00001220 849ac42f922da6f6837ca3832ed9fb08 167 SUPERFAMILY SSF52402 8 153 9.21E-16 T 01-11-2018 AFULGI_00001220 849ac42f922da6f6837ca3832ed9fb08 167 Pfam PF00582 Universal stress protein family 7 146 1.6E-17 T 01-11-2018 IPR006016 UspA AFULGI_00023770 3e95c6eb09f03783c37750cf10fed7e5 591 SUPERFAMILY SSF55785 131 257 2.42E-25 T 01-11-2018 IPR035965 PAS domain superfamily AFULGI_00023770 3e95c6eb09f03783c37750cf10fed7e5 591 SMART SM00091 264 330 4.2E-7 T 01-11-2018 IPR000014 PAS domain AFULGI_00023770 3e95c6eb09f03783c37750cf10fed7e5 591 SMART SM00091 23 89 7.0E-8 T 01-11-2018 IPR000014 PAS domain AFULGI_00023770 3e95c6eb09f03783c37750cf10fed7e5 591 SMART SM00091 146 212 6.7E-12 T 01-11-2018 IPR000014 PAS domain AFULGI_00023770 3e95c6eb09f03783c37750cf10fed7e5 591 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 24 141 2.8E-20 T 01-11-2018 IPR000014 PAS domain AFULGI_00023770 3e95c6eb09f03783c37750cf10fed7e5 591 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 260 378 2.3E-20 T 01-11-2018 IPR000014 PAS domain AFULGI_00023770 3e95c6eb09f03783c37750cf10fed7e5 591 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 142 264 4.9E-34 T 01-11-2018 IPR000014 PAS domain AFULGI_00023770 3e95c6eb09f03783c37750cf10fed7e5 591 Gene3D G3DSA:1.10.287.130 398 444 2.5E-33 T 01-11-2018 AFULGI_00023770 3e95c6eb09f03783c37750cf10fed7e5 591 Gene3D G3DSA:3.30.565.10 445 583 2.5E-33 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFULGI_00023770 3e95c6eb09f03783c37750cf10fed7e5 591 SMART SM00086 219 259 12.0 T 01-11-2018 IPR001610 PAC motif AFULGI_00023770 3e95c6eb09f03783c37750cf10fed7e5 591 SMART SM00086 94 134 5.3 T 01-11-2018 IPR001610 PAC motif AFULGI_00023770 3e95c6eb09f03783c37750cf10fed7e5 591 SMART SM00086 337 377 17.0 T 01-11-2018 IPR001610 PAC motif AFULGI_00023770 3e95c6eb09f03783c37750cf10fed7e5 591 Gene3D G3DSA:3.30.450.20 258 375 6.6E-18 T 01-11-2018 AFULGI_00023770 3e95c6eb09f03783c37750cf10fed7e5 591 Gene3D G3DSA:3.30.450.20 20 132 1.8E-18 T 01-11-2018 AFULGI_00023770 3e95c6eb09f03783c37750cf10fed7e5 591 Gene3D G3DSA:3.30.450.20 133 257 3.0E-24 T 01-11-2018 AFULGI_00023770 3e95c6eb09f03783c37750cf10fed7e5 591 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 485 584 2.6E-21 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFULGI_00023770 3e95c6eb09f03783c37750cf10fed7e5 591 Pfam PF13426 PAS domain 34 133 2.9E-8 T 01-11-2018 IPR000014 PAS domain AFULGI_00023770 3e95c6eb09f03783c37750cf10fed7e5 591 SUPERFAMILY SSF55785 35 143 1.57E-20 T 01-11-2018 IPR035965 PAS domain superfamily AFULGI_00023770 3e95c6eb09f03783c37750cf10fed7e5 591 SMART SM00387 480 586 9.3E-30 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFULGI_00023770 3e95c6eb09f03783c37750cf10fed7e5 591 Pfam PF08447 PAS fold 168 246 3.2E-14 T 01-11-2018 IPR013655 PAS fold-3 GO:0005515 AFULGI_00023770 3e95c6eb09f03783c37750cf10fed7e5 591 Pfam PF08447 PAS fold 285 366 3.0E-12 T 01-11-2018 IPR013655 PAS fold-3 GO:0005515 AFULGI_00023770 3e95c6eb09f03783c37750cf10fed7e5 591 SMART SM00388 390 447 0.006 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFULGI_00023770 3e95c6eb09f03783c37750cf10fed7e5 591 SUPERFAMILY SSF55874 446 584 4.58E-30 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFULGI_00023770 3e95c6eb09f03783c37750cf10fed7e5 591 PRINTS PR00344 Bacterial sensor protein C-terminal signature 518 532 6.2E-12 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFULGI_00023770 3e95c6eb09f03783c37750cf10fed7e5 591 PRINTS PR00344 Bacterial sensor protein C-terminal signature 546 564 6.2E-12 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFULGI_00023770 3e95c6eb09f03783c37750cf10fed7e5 591 PRINTS PR00344 Bacterial sensor protein C-terminal signature 570 583 6.2E-12 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFULGI_00023770 3e95c6eb09f03783c37750cf10fed7e5 591 SUPERFAMILY SSF55785 258 375 6.93E-17 T 01-11-2018 IPR035965 PAS domain superfamily AFULGI_00014510 f5fad4cabea74d9fcf84e2ac0fc812aa 174 PIRSF PIRSF005590 1 174 3.5E-75 T 01-11-2018 IPR001197 Ribosomal protein L10e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00014510 f5fad4cabea74d9fcf84e2ac0fc812aa 174 TIGRFAM TIGR00279 uL16_euk_arch: ribosomal protein uL16 1 171 1.9E-92 T 01-11-2018 IPR001197 Ribosomal protein L10e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00014510 f5fad4cabea74d9fcf84e2ac0fc812aa 174 SUPERFAMILY SSF54686 4 168 9.81E-62 T 01-11-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 AFULGI_00014510 f5fad4cabea74d9fcf84e2ac0fc812aa 174 Hamap MF_00448 50S ribosomal protein L10e [rpl10e]. 1 171 41.585 T 01-11-2018 IPR022981 Ribosomal protein L10e, archaea AFULGI_00014510 f5fad4cabea74d9fcf84e2ac0fc812aa 174 Pfam PF00252 Ribosomal protein L16p/L10e 14 162 7.3E-37 T 01-11-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 AFULGI_00014510 f5fad4cabea74d9fcf84e2ac0fc812aa 174 ProSitePatterns PS01257 Ribosomal protein L10e signature. 104 125 - T 01-11-2018 IPR018255 Ribosomal protein L10e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00014510 f5fad4cabea74d9fcf84e2ac0fc812aa 174 Gene3D G3DSA:3.90.1170.10 1 173 1.3E-70 T 01-11-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 AFULGI_00021660 7db4e70259b94cd2cd8ca703d60458d5 146 Pfam PF01280 Ribosomal protein L19e 2 145 3.9E-59 T 01-11-2018 IPR000196 Ribosomal protein L19/L19e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00021660 7db4e70259b94cd2cd8ca703d60458d5 146 ProSitePatterns PS00526 Ribosomal protein L19e signature. 6 25 - T 01-11-2018 IPR023638 Ribosomal protein L19/L19e conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00021660 7db4e70259b94cd2cd8ca703d60458d5 146 SMART SM01416 2 145 5.4E-90 T 01-11-2018 IPR000196 Ribosomal protein L19/L19e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00021660 7db4e70259b94cd2cd8ca703d60458d5 146 Gene3D G3DSA:1.10.1200.240 57 146 1.7E-27 T 01-11-2018 AFULGI_00021660 7db4e70259b94cd2cd8ca703d60458d5 146 Hamap MF_01475 50S ribosomal protein L19e [rpl19e]. 2 145 26.426 T 01-11-2018 IPR000196 Ribosomal protein L19/L19e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00021660 7db4e70259b94cd2cd8ca703d60458d5 146 Gene3D G3DSA:1.10.1650.10 1 55 2.1E-25 T 01-11-2018 IPR015972 Ribosomal protein L19/L19e, domain 1 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00021660 7db4e70259b94cd2cd8ca703d60458d5 146 SUPERFAMILY SSF48140 1 142 4.18E-57 T 01-11-2018 IPR035970 Ribosomal protein L19/L19e superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00020830 3b5a8de3e8d6cf656226603bd2d49470 350 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 16 147 1.7E-43 T 01-11-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFULGI_00020830 3b5a8de3e8d6cf656226603bd2d49470 350 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 276 320 3.0E-19 T 01-11-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFULGI_00020830 3b5a8de3e8d6cf656226603bd2d49470 350 Gene3D G3DSA:3.30.460.80 175 324 7.0E-23 T 01-11-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFULGI_00020830 3b5a8de3e8d6cf656226603bd2d49470 350 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 224 346 3.0E-27 T 01-11-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFULGI_00020830 3b5a8de3e8d6cf656226603bd2d49470 350 SUPERFAMILY SSF143243 203 349 1.05E-34 T 01-11-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFULGI_00020830 3b5a8de3e8d6cf656226603bd2d49470 350 Gene3D G3DSA:3.40.50.12280 11 164 5.4E-50 T 01-11-2018 AFULGI_00020830 3b5a8de3e8d6cf656226603bd2d49470 350 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 62 141 1.3E-20 T 01-11-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFULGI_00020830 3b5a8de3e8d6cf656226603bd2d49470 350 SUPERFAMILY SSF56770 15 151 6.54E-50 T 01-11-2018 AFULGI_00014560 e541f59055bc2e457556e2b504d9479f 292 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 2 289 12.251 T 01-11-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 AFULGI_00014560 e541f59055bc2e457556e2b504d9479f 292 Pfam PF00902 Sec-independent protein translocase protein (TatC) 10 272 2.8E-46 T 01-11-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 AFULGI_00014560 e541f59055bc2e457556e2b504d9479f 292 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 154 180 7.6E-8 T 01-11-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 AFULGI_00014560 e541f59055bc2e457556e2b504d9479f 292 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 205 233 7.6E-8 T 01-11-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 AFULGI_00013280 f4444c3ced8c771cde4dfdb46857d903 750 Pfam PF03176 MMPL family 78 392 2.2E-29 T 01-11-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 AFULGI_00013280 f4444c3ced8c771cde4dfdb46857d903 750 Pfam PF03176 MMPL family 561 731 1.1E-27 T 01-11-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 AFULGI_00013280 f4444c3ced8c771cde4dfdb46857d903 750 Gene3D G3DSA:1.20.1640.10 178 375 1.4E-18 T 01-11-2018 AFULGI_00013280 f4444c3ced8c771cde4dfdb46857d903 750 Gene3D G3DSA:1.20.1640.10 571 739 1.6E-16 T 01-11-2018 AFULGI_00013280 f4444c3ced8c771cde4dfdb46857d903 750 TIGRFAM TIGR00921 2A067: efflux transporter, putative, hydrophobe/amphiphile efflux-3 (HAE3) family 15 731 0.0 T 01-11-2018 IPR004767 Hydrophobe/amphiphile efflux-3 HAE3 AFULGI_00013280 f4444c3ced8c771cde4dfdb46857d903 750 SUPERFAMILY SSF82866 147 360 7.19E-35 T 01-11-2018 AFULGI_00013280 f4444c3ced8c771cde4dfdb46857d903 750 SUPERFAMILY SSF82866 542 731 4.32E-33 T 01-11-2018 AFULGI_00017730 3dc423c64903a375f93732d65905c52c 389 Gene3D G3DSA:3.60.15.10 1 244 6.3E-96 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFULGI_00017730 3dc423c64903a375f93732d65905c52c 389 Gene3D G3DSA:3.40.50.360 247 386 5.7E-43 T 01-11-2018 IPR029039 Flavoprotein-like superfamily AFULGI_00017730 3dc423c64903a375f93732d65905c52c 389 SUPERFAMILY SSF56281 10 285 4.87E-48 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFULGI_00017730 3dc423c64903a375f93732d65905c52c 389 Pfam PF00753 Metallo-beta-lactamase superfamily 33 178 1.9E-8 T 01-11-2018 IPR001279 Metallo-beta-lactamase AFULGI_00017730 3dc423c64903a375f93732d65905c52c 389 SUPERFAMILY SSF52218 249 389 2.16E-39 T 01-11-2018 IPR029039 Flavoprotein-like superfamily AFULGI_00017730 3dc423c64903a375f93732d65905c52c 389 SMART SM00849 33 225 1.9E-30 T 01-11-2018 IPR001279 Metallo-beta-lactamase AFULGI_00017730 3dc423c64903a375f93732d65905c52c 389 Pfam PF00258 Flavodoxin 253 382 3.6E-15 T 01-11-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 AFULGI_00017730 3dc423c64903a375f93732d65905c52c 389 PIRSF PIRSF005243 1 389 6.2E-186 T 01-11-2018 IPR016440 Rubredoxin-oxygen oxidoreductase GO:0009055|GO:0010181|GO:0016491|GO:0046872 AFULGI_00022950 7751e60fd708541da8276d7aacd97d13 201 Gene3D G3DSA:3.40.920.10 1 200 3.1E-55 T 01-11-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 AFULGI_00022950 7751e60fd708541da8276d7aacd97d13 201 TIGRFAM TIGR03334 IOR_beta: indolepyruvate ferredoxin oxidoreductase, beta subunit 3 190 6.2E-68 T 01-11-2018 IPR017719 Indolepyruvate ferredoxin oxidoreductase, beta subunit GO:0043805|GO:0055114 AFULGI_00022950 7751e60fd708541da8276d7aacd97d13 201 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 11 190 6.2E-47 T 01-11-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 AFULGI_00022950 7751e60fd708541da8276d7aacd97d13 201 SUPERFAMILY SSF53323 1 193 4.45E-42 T 01-11-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 AFULGI_00022700 6956e178d3ff2679b93ad397e7d62f46 296 SMART SM00729 11 212 4.3E-14 T 01-11-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 AFULGI_00022700 6956e178d3ff2679b93ad397e7d62f46 296 Pfam PF06463 Molybdenum Cofactor Synthesis C 201 294 4.9E-18 T 01-11-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AFULGI_00022700 6956e178d3ff2679b93ad397e7d62f46 296 Hamap MF_01225_A GTP 3',8-cyclase [moaA]. 2 295 43.854 T 01-11-2018 IPR013485 Molybdenum cofactor biosynthesis protein A, archaea GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823 AFULGI_00022700 6956e178d3ff2679b93ad397e7d62f46 296 Pfam PF04055 Radical SAM superfamily 17 170 3.1E-33 T 01-11-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFULGI_00022700 6956e178d3ff2679b93ad397e7d62f46 296 SUPERFAMILY SSF102114 3 269 3.66E-66 T 01-11-2018 AFULGI_00022700 6956e178d3ff2679b93ad397e7d62f46 296 Gene3D G3DSA:3.20.20.70 1 295 2.5E-73 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFULGI_00022700 6956e178d3ff2679b93ad397e7d62f46 296 TIGRFAM TIGR02668 moaA_archaeal: probable molybdenum cofactor biosynthesis protein A 2 295 1.3E-121 T 01-11-2018 IPR013485 Molybdenum cofactor biosynthesis protein A, archaea GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823 AFULGI_00022700 6956e178d3ff2679b93ad397e7d62f46 296 Pfam PF13353 4Fe-4S single cluster domain 18 113 6.8E-7 T 01-11-2018 AFULGI_00022700 6956e178d3ff2679b93ad397e7d62f46 296 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 17 28 - T 01-11-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AFULGI_00007160 6ab0d5fb8b521bcdf2dd27ba3ddc4984 330 SUPERFAMILY SSF53850 39 329 9.89E-85 T 01-11-2018 AFULGI_00007160 6ab0d5fb8b521bcdf2dd27ba3ddc4984 330 Pfam PF16868 NMT1-like family 43 327 6.5E-99 T 01-11-2018 IPR011852 TRAP transporter solute receptor, TAXI family AFULGI_00007160 6ab0d5fb8b521bcdf2dd27ba3ddc4984 330 Gene3D G3DSA:3.40.190.10 43 327 1.8E-111 T 01-11-2018 AFULGI_00007160 6ab0d5fb8b521bcdf2dd27ba3ddc4984 330 TIGRFAM TIGR02122 TRAP_TAXI: TRAP transporter solute receptor, TAXI family 1 327 1.2E-127 T 01-11-2018 IPR011852 TRAP transporter solute receptor, TAXI family AFULGI_00007160 6ab0d5fb8b521bcdf2dd27ba3ddc4984 330 Gene3D G3DSA:3.40.190.10 127 264 1.8E-111 T 01-11-2018 AFULGI_00026060 0e51d7786027b20bdd907ea30bb3f6ec 157 Pfam PF03692 Putative zinc- or iron-chelating domain 8 101 3.2E-14 T 01-11-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein AFULGI_00011220 1b01785c0248e88bfeda2809739084f9 397 Gene3D G3DSA:2.40.110.10 121 235 1.7E-49 T 01-11-2018 AFULGI_00011220 1b01785c0248e88bfeda2809739084f9 397 Gene3D G3DSA:1.20.140.10 236 388 8.6E-49 T 01-11-2018 AFULGI_00011220 1b01785c0248e88bfeda2809739084f9 397 SUPERFAMILY SSF56645 4 242 1.83E-90 T 01-11-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 AFULGI_00011220 1b01785c0248e88bfeda2809739084f9 397 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 339 358 - T 01-11-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 AFULGI_00011220 1b01785c0248e88bfeda2809739084f9 397 Gene3D G3DSA:1.10.540.10 2 120 2.7E-42 T 01-11-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 AFULGI_00011220 1b01785c0248e88bfeda2809739084f9 397 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 231 381 5.2E-51 T 01-11-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AFULGI_00011220 1b01785c0248e88bfeda2809739084f9 397 SUPERFAMILY SSF47203 229 384 1.03E-52 T 01-11-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 AFULGI_00011220 1b01785c0248e88bfeda2809739084f9 397 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 219 3.9E-32 T 01-11-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 AFULGI_00011220 1b01785c0248e88bfeda2809739084f9 397 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 8 118 4.5E-37 T 01-11-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 AFULGI_00011220 1b01785c0248e88bfeda2809739084f9 397 PIRSF PIRSF016578 4 389 2.0E-19 T 01-11-2018 AFULGI_00025730 2810b818b9e376932a820dc78f3a52fc 405 Gene3D G3DSA:1.20.140.10 253 402 1.8E-47 T 01-11-2018 AFULGI_00025730 2810b818b9e376932a820dc78f3a52fc 405 SUPERFAMILY SSF56645 2 220 7.59E-50 T 01-11-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 AFULGI_00025730 2810b818b9e376932a820dc78f3a52fc 405 Gene3D G3DSA:2.40.110.10 121 226 3.5E-31 T 01-11-2018 AFULGI_00025730 2810b818b9e376932a820dc78f3a52fc 405 Gene3D G3DSA:1.10.540.10 1 115 2.5E-12 T 01-11-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 AFULGI_00025730 2810b818b9e376932a820dc78f3a52fc 405 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 121 212 3.4E-23 T 01-11-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 AFULGI_00025730 2810b818b9e376932a820dc78f3a52fc 405 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 113 7.6E-10 T 01-11-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 AFULGI_00025730 2810b818b9e376932a820dc78f3a52fc 405 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 259 396 2.0E-41 T 01-11-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AFULGI_00025730 2810b818b9e376932a820dc78f3a52fc 405 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 355 374 - T 01-11-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 AFULGI_00025730 2810b818b9e376932a820dc78f3a52fc 405 SUPERFAMILY SSF47203 258 399 2.58E-48 T 01-11-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 AFULGI_00024150 d5d27135a461d1e5385a2faaba5a91c8 91 Gene3D G3DSA:3.40.30.10 1 82 7.9E-17 T 01-11-2018 AFULGI_00024150 d5d27135a461d1e5385a2faaba5a91c8 91 Pfam PF13192 Thioredoxin domain 5 79 4.9E-16 T 01-11-2018 IPR012336 Thioredoxin-like fold AFULGI_00024150 d5d27135a461d1e5385a2faaba5a91c8 91 ProSitePatterns PS00195 Glutaredoxin active site. 6 22 - T 01-11-2018 IPR011767 Glutaredoxin active site GO:0009055|GO:0045454 Reactome: R-HSA-499943 AFULGI_00024150 d5d27135a461d1e5385a2faaba5a91c8 91 SUPERFAMILY SSF52833 5 84 3.11E-17 T 01-11-2018 IPR036249 Thioredoxin-like superfamily AFULGI_00024150 d5d27135a461d1e5385a2faaba5a91c8 91 TIGRFAM TIGR00411 redox_disulf_1: redox-active disulfide protein 1 2 82 3.3E-42 T 01-11-2018 IPR004502 Thioredoxins/glutaredoxin GO:0009055|GO:0015035|GO:0045454 AFULGI_00026960 096a94b090b869b7e47e59accf43233b 157 Gene3D G3DSA:3.50.20.10 1 156 1.3E-46 T 01-11-2018 IPR016105 Pyruvoyl-dependent histidine/arginine decarboxylase, 3-layer sandwich domain GO:0006520|GO:0016831 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 AFULGI_00026960 096a94b090b869b7e47e59accf43233b 157 Pfam PF01862 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) 4 156 4.8E-54 T 01-11-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 AFULGI_00026960 096a94b090b869b7e47e59accf43233b 157 TIGRFAM TIGR00286 TIGR00286: arginine decarboxylase, pyruvoyl-dependent 3 157 9.3E-75 T 01-11-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 AFULGI_00026960 096a94b090b869b7e47e59accf43233b 157 SUPERFAMILY SSF56271 3 156 7.32E-50 T 01-11-2018 IPR016104 Pyruvoyl-dependent histidine/arginine decarboxylase GO:0006520|GO:0016831 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 AFULGI_00026960 096a94b090b869b7e47e59accf43233b 157 Hamap MF_01404 Pyruvoyl-dependent arginine decarboxylase [pdaD]. 1 157 60.844 T 01-11-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 AFULGI_00026960 096a94b090b869b7e47e59accf43233b 157 ProDom PD010449 DECARBOXYLASE PYRUVOYL-DEPENDENT ARGININE SUBUNIT ALPHA CONTAINS: BETA PVLARGDC LYA DECARBOX 5 139 1.0E-74 T 01-11-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 AFULGI_00026960 096a94b090b869b7e47e59accf43233b 157 PIRSF PIRSF005216 1 157 1.1E-58 T 01-11-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 AFULGI_00022190 9f44dd6b484ab5008049bf1f99457614 535 Gene3D G3DSA:3.40.50.300 345 533 7.0E-42 T 01-11-2018 AFULGI_00022190 9f44dd6b484ab5008049bf1f99457614 535 Pfam PF13087 AAA domain 337 508 7.5E-34 T 01-11-2018 AFULGI_00022190 9f44dd6b484ab5008049bf1f99457614 535 SUPERFAMILY SSF52540 132 521 6.79E-50 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00022190 9f44dd6b484ab5008049bf1f99457614 535 SMART SM00382 148 378 2.9E-4 T 01-11-2018 IPR003593 AAA+ ATPase domain AFULGI_00022190 9f44dd6b484ab5008049bf1f99457614 535 Gene3D G3DSA:3.40.50.300 76 339 1.9E-36 T 01-11-2018 AFULGI_00022190 9f44dd6b484ab5008049bf1f99457614 535 Pfam PF13086 AAA domain 240 314 2.5E-12 T 01-11-2018 AFULGI_00016210 9a39f58213eb6639b45aa8c626f5cc58 200 Pfam PF07788 PD-(D/E)XK nuclease superfamily 128 194 7.4E-22 T 01-11-2018 IPR012431 PD-(D/E)XK nuclease AFULGI_00016210 9a39f58213eb6639b45aa8c626f5cc58 200 Pfam PF12644 Protein of unknown function (DUF3782) 46 125 1.4E-25 T 01-11-2018 IPR024271 Protein of unknown function DUF3782 AFULGI_00016210 9a39f58213eb6639b45aa8c626f5cc58 200 SUPERFAMILY SSF52980 12 195 4.29E-9 T 01-11-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 AFULGI_00009430 283db15aa6a4591277ba714e66d936e5 432 SUPERFAMILY SSF51366 1 212 2.95E-42 T 01-11-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 AFULGI_00009430 283db15aa6a4591277ba714e66d936e5 432 SMART SM00934 5 206 2.5E-37 T 01-11-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AFULGI_00009430 283db15aa6a4591277ba714e66d936e5 432 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 6 205 5.9E-23 T 01-11-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AFULGI_00009430 283db15aa6a4591277ba714e66d936e5 432 Gene3D G3DSA:3.20.20.70 5 211 1.3E-68 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFULGI_00009430 283db15aa6a4591277ba714e66d936e5 432 SUPERFAMILY SSF89562 235 396 1.44E-45 T 01-11-2018 IPR036704 Ribonuclease E inhibitor RraA/RraA-like superfamily AFULGI_00009430 283db15aa6a4591277ba714e66d936e5 432 PIRSF PIRSF037137 1 432 3.4E-241 T 01-11-2018 IPR017120 Bifunctional 3-hexulose-6-phosphate synthase/demethylmenaquinone methyltransferase, predicted KEGG: 00030+4.1.2.43|KEGG: 00680+4.1.2.43|MetaCyc: PWY-1861|MetaCyc: PWY-7796 AFULGI_00009430 283db15aa6a4591277ba714e66d936e5 432 Pfam PF03737 Aldolase/RraA 239 385 1.3E-43 T 01-11-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein AFULGI_00009430 283db15aa6a4591277ba714e66d936e5 432 Gene3D G3DSA:3.50.30.40 235 394 1.2E-46 T 01-11-2018 AFULGI_00008290 f52d30584a129dccc6b8355116935a21 299 SUPERFAMILY SSF111331 2 294 3.66E-18 T 01-11-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily AFULGI_00008290 f52d30584a129dccc6b8355116935a21 299 Pfam PF01513 ATP-NAD kinase 2 118 6.7E-8 T 01-11-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 AFULGI_00008290 f52d30584a129dccc6b8355116935a21 299 Gene3D G3DSA:3.40.50.10330 1 110 1.3E-8 T 01-11-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 AFULGI_00004840 bf1167086359527a382d9baced57cbf4 79 Gene3D G3DSA:2.10.260.10 7 52 8.5E-10 T 01-11-2018 AFULGI_00004840 bf1167086359527a382d9baced57cbf4 79 ProDom PD058861 TRANSCRIPTIONAL ABRB FAMILY REGULATOR AF0476 REGULATOR 3 78 5.0E-36 T 01-11-2018 AFULGI_00004840 bf1167086359527a382d9baced57cbf4 79 SMART SM00966 13 64 1.1E-4 T 01-11-2018 IPR007159 SpoVT-AbrB domain GO:0003677 AFULGI_00004840 bf1167086359527a382d9baced57cbf4 79 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 16 41 6.6E-6 T 01-11-2018 IPR007159 SpoVT-AbrB domain GO:0003677 AFULGI_00004840 bf1167086359527a382d9baced57cbf4 79 SUPERFAMILY SSF89447 11 43 5.62E-9 T 01-11-2018 IPR037914 SpoVT-AbrB domain superfamily AFULGI_00004840 bf1167086359527a382d9baced57cbf4 79 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 14 40 3.6E-9 T 01-11-2018 IPR007159 SpoVT-AbrB domain GO:0003677 AFULGI_00026580 23ce5d67f5e0c0fa2e23c9ede6a0fa62 798 Pfam PF12838 4Fe-4S dicluster domain 404 457 2.3E-7 T 01-11-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFULGI_00026580 23ce5d67f5e0c0fa2e23c9ede6a0fa62 798 Gene3D G3DSA:3.40.50.2030 216 490 0.0 T 01-11-2018 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 AFULGI_00026580 23ce5d67f5e0c0fa2e23c9ede6a0fa62 798 SUPERFAMILY SSF46548 386 465 2.79E-15 T 01-11-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 AFULGI_00026580 23ce5d67f5e0c0fa2e23c9ede6a0fa62 798 Pfam PF03063 Prismane/CO dehydrogenase family 67 681 9.2E-111 T 01-11-2018 IPR004137 Hydroxylamine reductase/Ni-containing CO dehydrogenase GO:0016491|GO:0055114 KEGG: 00910+1.7.99.1 AFULGI_00026580 23ce5d67f5e0c0fa2e23c9ede6a0fa62 798 Gene3D G3DSA:3.40.50.2030 36 764 0.0 T 01-11-2018 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 AFULGI_00026580 23ce5d67f5e0c0fa2e23c9ede6a0fa62 798 TIGRFAM TIGR00314 cdhA: CO dehydrogenase/acetyl-CoA synthase complex, epsilon subunit 4 788 0.0 T 01-11-2018 IPR004460 Acetyl-CoA decarbonylase/synthase complex subunit alpha GO:0006084|GO:0055114 KEGG: 00633+1.2.7.4|KEGG: 00680+1.2.7.4|KEGG: 00720+1.2.7.4|MetaCyc: PWY-5372|MetaCyc: PWY-6780|MetaCyc: PWY-7784 AFULGI_00026580 23ce5d67f5e0c0fa2e23c9ede6a0fa62 798 Hamap MF_01137 Acetyl-CoA decarbonylase/synthase complex subunit alpha [cdhA]. 3 788 45.389 T 01-11-2018 IPR004460 Acetyl-CoA decarbonylase/synthase complex subunit alpha GO:0006084|GO:0055114 KEGG: 00633+1.2.7.4|KEGG: 00680+1.2.7.4|KEGG: 00720+1.2.7.4|MetaCyc: PWY-5372|MetaCyc: PWY-6780|MetaCyc: PWY-7784 AFULGI_00026580 23ce5d67f5e0c0fa2e23c9ede6a0fa62 798 Gene3D G3DSA:1.10.1060.10 400 479 0.0 T 01-11-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 AFULGI_00026580 23ce5d67f5e0c0fa2e23c9ede6a0fa62 798 SUPERFAMILY SSF56821 15 733 6.15E-158 T 01-11-2018 IPR011254 Prismane-like superfamily GO:0003824|GO:0016491|GO:0055114 AFULGI_00026580 23ce5d67f5e0c0fa2e23c9ede6a0fa62 798 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 443 454 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFULGI_00000160 da1086c882827f25f9f0a832e0d890ac 397 Pfam PF00108 Thiolase, N-terminal domain 4 225 3.3E-21 T 01-11-2018 IPR020616 Thiolase, N-terminal GO:0016747 AFULGI_00000160 da1086c882827f25f9f0a832e0d890ac 397 Pfam PF02803 Thiolase, C-terminal domain 266 353 1.5E-9 T 01-11-2018 IPR020617 Thiolase, C-terminal GO:0016747 AFULGI_00000160 da1086c882827f25f9f0a832e0d890ac 397 ProSitePatterns PS00737 Thiolases signature 2. 325 341 - T 01-11-2018 IPR020613 Thiolase, conserved site GO:0016747 AFULGI_00000160 da1086c882827f25f9f0a832e0d890ac 397 PIRSF PIRSF000429 1 377 1.0E-55 T 01-11-2018 IPR002155 Thiolase GO:0016747 AFULGI_00000160 da1086c882827f25f9f0a832e0d890ac 397 Gene3D G3DSA:3.40.47.10 1 386 2.9E-115 T 01-11-2018 IPR016039 Thiolase-like GO:0003824 AFULGI_00000160 da1086c882827f25f9f0a832e0d890ac 397 SUPERFAMILY SSF53901 3 230 2.14E-40 T 01-11-2018 IPR016039 Thiolase-like GO:0003824 AFULGI_00000160 da1086c882827f25f9f0a832e0d890ac 397 SUPERFAMILY SSF53901 234 385 3.56E-27 T 01-11-2018 IPR016039 Thiolase-like GO:0003824 AFULGI_00004890 f9595760f37774c0cfc2d30f41fb62eb 211 Pfam PF00227 Proteasome subunit 7 189 9.2E-59 T 01-11-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 AFULGI_00004890 f9595760f37774c0cfc2d30f41fb62eb 211 PRINTS PR00141 Proteasome component signature 139 150 3.1E-8 T 01-11-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 AFULGI_00004890 f9595760f37774c0cfc2d30f41fb62eb 211 PRINTS PR00141 Proteasome component signature 175 186 3.1E-8 T 01-11-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 AFULGI_00004890 f9595760f37774c0cfc2d30f41fb62eb 211 PRINTS PR00141 Proteasome component signature 17 32 3.1E-8 T 01-11-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 AFULGI_00004890 f9595760f37774c0cfc2d30f41fb62eb 211 SUPERFAMILY SSF56235 4 209 9.36E-67 T 01-11-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFULGI_00004890 f9595760f37774c0cfc2d30f41fb62eb 211 Gene3D G3DSA:3.60.20.10 2 211 2.1E-69 T 01-11-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFULGI_00004890 f9595760f37774c0cfc2d30f41fb62eb 211 TIGRFAM TIGR03634 arc_protsome_B: proteasome endopeptidase complex, archaeal, beta subunit 9 193 2.7E-83 T 01-11-2018 IPR019983 Peptidase T1A, proteasome beta-subunit, archaeal GO:0004175|GO:0005839|GO:0051603 AFULGI_00004890 f9595760f37774c0cfc2d30f41fb62eb 211 ProSitePatterns PS00854 Proteasome beta-type subunits signature. 13 60 - T 01-11-2018 IPR016050 Proteasome beta-type subunit, conserved site GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 AFULGI_00004890 f9595760f37774c0cfc2d30f41fb62eb 211 Hamap MF_02113_A Proteasome subunit beta [prcB]. 5 202 38.671 T 01-11-2018 IPR019983 Peptidase T1A, proteasome beta-subunit, archaeal GO:0004175|GO:0005839|GO:0051603 AFULGI_00000260 a2f5043a85f00eb3525ae6dd98b8bc69 371 SUPERFAMILY SSF53383 8 370 7.05E-65 T 01-11-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFULGI_00000260 a2f5043a85f00eb3525ae6dd98b8bc69 371 TIGRFAM TIGR02539 SepCysS: O-phospho-L-seryl-tRNA:Cys-tRNA synthase 3 370 6.6E-181 T 01-11-2018 IPR013375 O-phosphoseryl-tRNA:Cys-tRNA synthase, archaea GO:0043766 KEGG: 00970+2.5.1.73|MetaCyc: PWY-6308 AFULGI_00000260 a2f5043a85f00eb3525ae6dd98b8bc69 371 Hamap MF_01675 O-phospho-L-seryl-tRNA:Cys-tRNA synthase. 1 371 58.219 T 01-11-2018 IPR013375 O-phosphoseryl-tRNA:Cys-tRNA synthase, archaea GO:0043766 KEGG: 00970+2.5.1.73|MetaCyc: PWY-6308 AFULGI_00000260 a2f5043a85f00eb3525ae6dd98b8bc69 371 Gene3D G3DSA:3.90.1150.10 7 368 4.4E-184 T 01-11-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFULGI_00000260 a2f5043a85f00eb3525ae6dd98b8bc69 371 Gene3D G3DSA:3.40.640.10 18 269 4.4E-184 T 01-11-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFULGI_00000260 a2f5043a85f00eb3525ae6dd98b8bc69 371 Pfam PF05889 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS 34 368 5.9E-98 T 01-11-2018 IPR008829 SepSecS/SepCysS family GO:0016740 Reactome: R-HSA-2408557 AFULGI_00005140 88020ba25b5c08480ffba467ed99d97f 287 Gene3D G3DSA:3.60.15.10 8 267 2.2E-14 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFULGI_00005140 88020ba25b5c08480ffba467ed99d97f 287 Hamap MF_01406 UPF0282 protein . 1 283 41.865 T 01-11-2018 IPR014426 Uncharacterised protein family UPF0282, hydrolase, metallo-beta-lactamase AFULGI_00005140 88020ba25b5c08480ffba467ed99d97f 287 SUPERFAMILY SSF56281 15 260 2.49E-17 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFULGI_00005140 88020ba25b5c08480ffba467ed99d97f 287 PIRSF PIRSF004944 1 287 1.4E-124 T 01-11-2018 IPR014426 Uncharacterised protein family UPF0282, hydrolase, metallo-beta-lactamase AFULGI_00014670 81e2de99256cc9f846225e41f57e34f5 357 SUPERFAMILY SSF53850 34 355 5.65E-88 T 01-11-2018 AFULGI_00014670 81e2de99256cc9f846225e41f57e34f5 357 TIGRFAM TIGR00975 3a0107s03: phosphate ABC transporter, phosphate-binding protein PstS 36 352 6.1E-118 T 01-11-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 AFULGI_00014670 81e2de99256cc9f846225e41f57e34f5 357 Gene3D G3DSA:3.40.190.10 114 300 6.6E-109 T 01-11-2018 AFULGI_00014670 81e2de99256cc9f846225e41f57e34f5 357 Gene3D G3DSA:3.40.190.10 39 348 6.6E-109 T 01-11-2018 AFULGI_00014670 81e2de99256cc9f846225e41f57e34f5 357 Pfam PF12849 PBP superfamily domain 27 330 2.9E-62 T 01-11-2018 IPR024370 PBP domain AFULGI_00014670 81e2de99256cc9f846225e41f57e34f5 357 PIRSF PIRSF002756 6 357 3.2E-116 T 01-11-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 AFULGI_00024550 17982f6953e53b95030beab3c391a6a7 208 Gene3D G3DSA:3.10.290.10 1 52 1.9E-17 T 01-11-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 AFULGI_00024550 17982f6953e53b95030beab3c391a6a7 208 SMART SM00363 1 61 5.3E-17 T 01-11-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00024550 17982f6953e53b95030beab3c391a6a7 208 Pfam PF01479 S4 domain 1 48 1.9E-15 T 01-11-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00024550 17982f6953e53b95030beab3c391a6a7 208 TIGRFAM TIGR00478 tly: TlyA family rRNA methyltransferase/putative hemolysin 2 200 2.7E-66 T 01-11-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 AFULGI_00024550 17982f6953e53b95030beab3c391a6a7 208 Pfam PF01728 FtsJ-like methyltransferase 55 148 8.1E-9 T 01-11-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 AFULGI_00024550 17982f6953e53b95030beab3c391a6a7 208 SUPERFAMILY SSF53335 2 188 2.52E-23 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFULGI_00024550 17982f6953e53b95030beab3c391a6a7 208 Gene3D G3DSA:3.40.50.150 53 203 1.0E-16 T 01-11-2018 AFULGI_00009870 beccbd6caa69fe1d608bc058594ea8d5 174 SUPERFAMILY SSF52972 1 173 2.79E-48 T 01-11-2018 IPR029001 Inosine triphosphate pyrophosphatase-like AFULGI_00009870 beccbd6caa69fe1d608bc058594ea8d5 174 Gene3D G3DSA:3.90.950.10 1 174 1.2E-53 T 01-11-2018 IPR029001 Inosine triphosphate pyrophosphatase-like AFULGI_00009870 beccbd6caa69fe1d608bc058594ea8d5 174 Hamap MF_00648 Non-canonical purine NTP phosphatase. 2 173 32.49 T 01-11-2018 IPR002786 Non-canonical purine NTP phosphatase AFULGI_00009870 beccbd6caa69fe1d608bc058594ea8d5 174 Pfam PF01931 Protein of unknown function DUF84 7 168 5.6E-50 T 01-11-2018 IPR026533 Non-canonical purine NTP phosphatase/PRRC1 AFULGI_00009870 beccbd6caa69fe1d608bc058594ea8d5 174 TIGRFAM TIGR00258 TIGR00258: inosine/xanthosine triphosphatase 6 174 5.9E-81 T 01-11-2018 IPR002786 Non-canonical purine NTP phosphatase AFULGI_00024910 f27b1e7eefc619ebb6c4caaf6f9fdf97 140 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 96 113 - T 01-11-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 AFULGI_00024910 f27b1e7eefc619ebb6c4caaf6f9fdf97 140 SUPERFAMILY SSF51230 66 139 9.03E-24 T 01-11-2018 IPR011053 Single hybrid motif AFULGI_00024910 f27b1e7eefc619ebb6c4caaf6f9fdf97 140 Pfam PF00364 Biotin-requiring enzyme 73 139 9.5E-22 T 01-11-2018 IPR000089 Biotin/lipoyl attachment AFULGI_00024910 f27b1e7eefc619ebb6c4caaf6f9fdf97 140 Gene3D G3DSA:2.40.50.100 63 140 1.8E-26 T 01-11-2018 AFULGI_00015580 15462e0cce53751088ae978ee0f6ddc0 410 SUPERFAMILY SSF53300 244 403 7.57E-18 T 01-11-2018 IPR036465 von Willebrand factor A-like domain superfamily AFULGI_00015580 15462e0cce53751088ae978ee0f6ddc0 410 Pfam PF13519 von Willebrand factor type A domain 244 336 1.5E-6 T 01-11-2018 IPR002035 von Willebrand factor, type A AFULGI_00015580 15462e0cce53751088ae978ee0f6ddc0 410 SMART SM00327 240 403 1.4E-5 T 01-11-2018 IPR002035 von Willebrand factor, type A AFULGI_00015580 15462e0cce53751088ae978ee0f6ddc0 410 Gene3D G3DSA:3.40.50.410 241 408 8.7E-17 T 01-11-2018 IPR036465 von Willebrand factor A-like domain superfamily AFULGI_00007620 85a0807a1624f54d1635a5206eee9b69 236 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 50 58 - T 01-11-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 AFULGI_00007620 85a0807a1624f54d1635a5206eee9b69 236 Pfam PF13183 4Fe-4S dicluster domain 141 212 1.4E-10 T 01-11-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFULGI_00007620 85a0807a1624f54d1635a5206eee9b69 236 SUPERFAMILY SSF54292 2 96 1.97E-28 T 01-11-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 AFULGI_00007620 85a0807a1624f54d1635a5206eee9b69 236 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 4 103 9.2E-34 T 01-11-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFULGI_00007620 85a0807a1624f54d1635a5206eee9b69 236 SUPERFAMILY SSF46548 101 225 3.49E-31 T 01-11-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 AFULGI_00007620 85a0807a1624f54d1635a5206eee9b69 236 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 6 222 8.9E-92 T 01-11-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFULGI_00007620 85a0807a1624f54d1635a5206eee9b69 236 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 142 153 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFULGI_00007620 85a0807a1624f54d1635a5206eee9b69 236 Gene3D G3DSA:1.10.1060.10 99 231 2.4E-43 T 01-11-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 AFULGI_00007620 85a0807a1624f54d1635a5206eee9b69 236 Gene3D G3DSA:3.10.20.30 1 98 1.4E-36 T 01-11-2018 IPR012675 Beta-grasp domain superfamily AFULGI_00006290 7a586337ebe913a3822643af69e78158 262 Pfam PF03787 RAMP superfamily 14 219 1.9E-19 T 01-11-2018 IPR005537 CRISPR type III-associated RAMP protein AFULGI_00006290 7a586337ebe913a3822643af69e78158 262 TIGRFAM TIGR02582 cas7_TM1809: CRISPR type III-A/MTUBE-associated RAMP protein Csm3 7 220 1.0E-65 T 01-11-2018 IPR013412 CRISPR-associated RAMP Csm3 AFULGI_00021130 27fed421ac5bc985c42a1b6583af0965 445 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 324 430 3.2E-18 T 01-11-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 AFULGI_00021130 27fed421ac5bc985c42a1b6583af0965 445 SUPERFAMILY SSF55424 318 439 2.75E-24 T 01-11-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 AFULGI_00021130 27fed421ac5bc985c42a1b6583af0965 445 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 143 168 3.1E-21 T 01-11-2018 AFULGI_00021130 27fed421ac5bc985c42a1b6583af0965 445 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 3.1E-21 T 01-11-2018 AFULGI_00021130 27fed421ac5bc985c42a1b6583af0965 445 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 393 413 3.1E-21 T 01-11-2018 AFULGI_00021130 27fed421ac5bc985c42a1b6583af0965 445 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 270 277 3.1E-21 T 01-11-2018 AFULGI_00021130 27fed421ac5bc985c42a1b6583af0965 445 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 229 243 3.1E-21 T 01-11-2018 AFULGI_00021130 27fed421ac5bc985c42a1b6583af0965 445 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 299 2.9E-65 T 01-11-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFULGI_00021130 27fed421ac5bc985c42a1b6583af0965 445 SUPERFAMILY SSF51905 1 307 1.41E-46 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFULGI_00021130 27fed421ac5bc985c42a1b6583af0965 445 Gene3D G3DSA:3.50.50.60 106 428 4.4E-118 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFULGI_00021130 27fed421ac5bc985c42a1b6583af0965 445 Gene3D G3DSA:3.50.50.60 5 335 4.4E-118 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFULGI_00021130 27fed421ac5bc985c42a1b6583af0965 445 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 97 115 6.4E-27 T 01-11-2018 AFULGI_00021130 27fed421ac5bc985c42a1b6583af0965 445 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 228 244 6.4E-27 T 01-11-2018 AFULGI_00021130 27fed421ac5bc985c42a1b6583af0965 445 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 255 277 6.4E-27 T 01-11-2018 AFULGI_00021130 27fed421ac5bc985c42a1b6583af0965 445 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 143 161 6.4E-27 T 01-11-2018 AFULGI_00021130 27fed421ac5bc985c42a1b6583af0965 445 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 6.4E-27 T 01-11-2018 AFULGI_00015490 e2fe77cd4bb138ab28713afbfeab6474 328 Hamap MF_00200 RNA 3'-terminal phosphate cyclase [rtcA]. 1 328 40.946 T 01-11-2018 IPR017770 RNA 3'-terminal phosphate cyclase type 1 GO:0003963|GO:0006396 AFULGI_00015490 e2fe77cd4bb138ab28713afbfeab6474 328 Pfam PF01137 RNA 3'-terminal phosphate cyclase 9 318 3.8E-84 T 01-11-2018 IPR023797 RNA 3'-terminal phosphate cyclase domain AFULGI_00015490 e2fe77cd4bb138ab28713afbfeab6474 328 Pfam PF05189 RNA 3'-terminal phosphate cyclase (RTC), insert domain 185 267 4.6E-16 T 01-11-2018 IPR013791 RNA 3'-terminal phosphate cyclase, insert domain AFULGI_00015490 e2fe77cd4bb138ab28713afbfeab6474 328 Gene3D G3DSA:3.30.360.20 178 268 3.0E-121 T 01-11-2018 IPR036553 RNA 3'-terminal phosphate cyclase, insert domain superfamily AFULGI_00015490 e2fe77cd4bb138ab28713afbfeab6474 328 Gene3D G3DSA:3.65.10.20 3 315 3.0E-121 T 01-11-2018 IPR037136 RNA 3'-terminal phosphate cyclase domain superfamily AFULGI_00015490 e2fe77cd4bb138ab28713afbfeab6474 328 TIGRFAM TIGR03399 RNA_3prim_cycl: RNA 3'-phosphate cyclase 2 318 2.6E-137 T 01-11-2018 IPR017770 RNA 3'-terminal phosphate cyclase type 1 GO:0003963|GO:0006396 AFULGI_00015490 e2fe77cd4bb138ab28713afbfeab6474 328 PIRSF PIRSF005378 1 326 3.3E-113 T 01-11-2018 IPR000228 RNA 3'-terminal phosphate cyclase GO:0006396 AFULGI_00015490 e2fe77cd4bb138ab28713afbfeab6474 328 ProSitePatterns PS01287 RNA 3'-terminal phosphate cyclase signature. 154 164 - T 01-11-2018 IPR020719 RNA 3'-terminal phosphate cyclase-like, conserved site AFULGI_00015490 e2fe77cd4bb138ab28713afbfeab6474 328 SUPERFAMILY SSF55205 1 224 7.19E-71 T 01-11-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 AFULGI_00010450 faaa7d36d09ed5797688334cfdd304e1 359 Pfam PF13374 Tetratricopeptide repeat 44 75 4.2E-4 T 01-11-2018 AFULGI_00010450 faaa7d36d09ed5797688334cfdd304e1 359 Pfam PF13374 Tetratricopeptide repeat 85 112 0.0067 T 01-11-2018 AFULGI_00010450 faaa7d36d09ed5797688334cfdd304e1 359 SMART SM00028 84 117 0.019 T 01-11-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFULGI_00010450 faaa7d36d09ed5797688334cfdd304e1 359 SMART SM00028 39 72 0.13 T 01-11-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFULGI_00010450 faaa7d36d09ed5797688334cfdd304e1 359 SMART SM00028 163 196 38.0 T 01-11-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFULGI_00010450 faaa7d36d09ed5797688334cfdd304e1 359 SMART SM00028 123 156 160.0 T 01-11-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFULGI_00010450 faaa7d36d09ed5797688334cfdd304e1 359 SUPERFAMILY SSF48452 85 208 5.96E-14 T 01-11-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFULGI_00010450 faaa7d36d09ed5797688334cfdd304e1 359 Pfam PF13424 Tetratricopeptide repeat 122 194 1.5E-7 T 01-11-2018 AFULGI_00010450 faaa7d36d09ed5797688334cfdd304e1 359 Gene3D G3DSA:1.25.40.10 2 123 9.1E-14 T 01-11-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFULGI_00010450 faaa7d36d09ed5797688334cfdd304e1 359 Gene3D G3DSA:1.25.40.10 124 215 6.2E-10 T 01-11-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFULGI_00015290 a9b07d6babddc335ab4bc6153037da46 589 Gene3D G3DSA:1.10.3080.10 9 456 1.8E-104 T 01-11-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 AFULGI_00015290 a9b07d6babddc335ab4bc6153037da46 589 Pfam PF00571 CBS domain 467 511 1.2E-6 T 01-11-2018 IPR000644 CBS domain AFULGI_00015290 a9b07d6babddc335ab4bc6153037da46 589 Pfam PF00571 CBS domain 524 579 1.7E-16 T 01-11-2018 IPR000644 CBS domain AFULGI_00015290 a9b07d6babddc335ab4bc6153037da46 589 Gene3D G3DSA:3.10.580.10 457 586 2.8E-29 T 01-11-2018 AFULGI_00015290 a9b07d6babddc335ab4bc6153037da46 589 SUPERFAMILY SSF81340 11 446 1.15E-104 T 01-11-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 AFULGI_00015290 a9b07d6babddc335ab4bc6153037da46 589 SMART SM00116 531 581 4.7E-12 T 01-11-2018 IPR000644 CBS domain AFULGI_00015290 a9b07d6babddc335ab4bc6153037da46 589 SMART SM00116 469 516 6.2E-6 T 01-11-2018 IPR000644 CBS domain AFULGI_00015290 a9b07d6babddc335ab4bc6153037da46 589 SUPERFAMILY SSF54631 448 582 8.46E-31 T 01-11-2018 AFULGI_00015290 a9b07d6babddc335ab4bc6153037da46 589 PRINTS PR00762 Chloride channel signature 378 394 3.3E-22 T 01-11-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 AFULGI_00015290 a9b07d6babddc335ab4bc6153037da46 589 PRINTS PR00762 Chloride channel signature 343 363 3.3E-22 T 01-11-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 AFULGI_00015290 a9b07d6babddc335ab4bc6153037da46 589 PRINTS PR00762 Chloride channel signature 396 415 3.3E-22 T 01-11-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 AFULGI_00015290 a9b07d6babddc335ab4bc6153037da46 589 PRINTS PR00762 Chloride channel signature 120 139 3.3E-22 T 01-11-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 AFULGI_00015290 a9b07d6babddc335ab4bc6153037da46 589 PRINTS PR00762 Chloride channel signature 171 190 3.3E-22 T 01-11-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 AFULGI_00015290 a9b07d6babddc335ab4bc6153037da46 589 Pfam PF00654 Voltage gated chloride channel 77 428 4.3E-98 T 01-11-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 AFULGI_00013580 5b7682322b78c11a8184e21c6da7de51 271 Hamap MF_00421 Phosphoribosylformylglycinamidine synthase subunit PurQ [purQ]. 6 266 36.036 T 01-11-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 AFULGI_00013580 5b7682322b78c11a8184e21c6da7de51 271 PIRSF PIRSF001586 4 271 2.2E-83 T 01-11-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 AFULGI_00013580 5b7682322b78c11a8184e21c6da7de51 271 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 6 267 4.3E-64 T 01-11-2018 AFULGI_00013580 5b7682322b78c11a8184e21c6da7de51 271 SMART SM01211 5 268 7.8E-103 T 01-11-2018 AFULGI_00013580 5b7682322b78c11a8184e21c6da7de51 271 TIGRFAM TIGR01737 FGAM_synth_I: phosphoribosylformylglycinamidine synthase I 6 267 4.0E-97 T 01-11-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 AFULGI_00013580 5b7682322b78c11a8184e21c6da7de51 271 Gene3D G3DSA:3.40.50.880 1 268 2.8E-77 T 01-11-2018 IPR029062 Class I glutamine amidotransferase-like AFULGI_00013580 5b7682322b78c11a8184e21c6da7de51 271 SUPERFAMILY SSF52317 5 268 1.26E-70 T 01-11-2018 IPR029062 Class I glutamine amidotransferase-like AFULGI_00021210 453d86ebc04c8e79038111c74aeb7180 341 Gene3D G3DSA:3.30.70.2940 1 86 5.2E-22 T 01-11-2018 AFULGI_00021210 453d86ebc04c8e79038111c74aeb7180 341 Gene3D G3DSA:3.30.70.2950 232 341 1.7E-32 T 01-11-2018 AFULGI_00021210 453d86ebc04c8e79038111c74aeb7180 341 TIGRFAM TIGR01888 cas_cmr3: CRISPR type III-B/RAMP module-associated protein Cmr3 4 341 1.6E-105 T 01-11-2018 IPR010165 CRISPR-associated protein, TM1793 AFULGI_00021210 453d86ebc04c8e79038111c74aeb7180 341 Pfam PF09700 CRISPR-associated protein (Cas_Cmr3) 4 341 6.9E-86 T 01-11-2018 IPR019117 CRISPR-associated protein, Cmr3 AFULGI_00003890 2558ae176378e30805f94136ee872ae6 333 SUPERFAMILY SSF102114 14 294 1.22E-43 T 01-11-2018 AFULGI_00003890 2558ae176378e30805f94136ee872ae6 333 Pfam PF04055 Radical SAM superfamily 37 190 2.5E-15 T 01-11-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFULGI_00003890 2558ae176378e30805f94136ee872ae6 333 Gene3D G3DSA:3.20.20.70 1 328 4.2E-51 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFULGI_00003890 2558ae176378e30805f94136ee872ae6 333 PIRSF PIRSF004762 1 333 4.1E-103 T 01-11-2018 AFULGI_00003890 2558ae176378e30805f94136ee872ae6 333 TIGRFAM TIGR00423 TIGR00423: radical SAM domain protein, CofH subfamily 28 329 5.6E-138 T 01-11-2018 IPR020050 FO synthase, subunit 2 GO:0016765 KEGG: 00680+2.5.1.77 AFULGI_00011260 9cf9cc330126275b362084aced0ea333 527 Pfam PF01935 Domain of unknown function DUF87 129 356 8.1E-48 T 01-11-2018 IPR002789 Helicase HerA, central domain AFULGI_00011260 9cf9cc330126275b362084aced0ea333 527 Pfam PF05872 Bacterial protein of unknown function (DUF853) 379 478 1.5E-6 T 01-11-2018 IPR033186 Helicase HerA-like C-terminal AFULGI_00011260 9cf9cc330126275b362084aced0ea333 527 Pfam PF09378 HAS barrel domain 4 95 1.2E-16 T 01-11-2018 IPR018538 Helicase HerA, barrel domain AFULGI_00011260 9cf9cc330126275b362084aced0ea333 527 Gene3D G3DSA:3.40.50.300 115 295 1.3E-21 T 01-11-2018 AFULGI_00011260 9cf9cc330126275b362084aced0ea333 527 Gene3D G3DSA:3.40.50.300 301 507 2.5E-56 T 01-11-2018 AFULGI_00011260 9cf9cc330126275b362084aced0ea333 527 SUPERFAMILY SSF52540 97 498 2.57E-39 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00021820 f2da3c5515d56522e090f6899f38aa19 81 Pfam PF00276 Ribosomal protein L23 3 66 3.9E-13 T 01-11-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 AFULGI_00021820 f2da3c5515d56522e090f6899f38aa19 81 TIGRFAM TIGR03636 uL23_arch: ribosomal protein uL23 7 81 1.3E-32 T 01-11-2018 IPR019985 Ribosomal protein L23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00021820 f2da3c5515d56522e090f6899f38aa19 81 Gene3D G3DSA:3.30.70.330 1 81 1.4E-28 T 01-11-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily AFULGI_00021820 f2da3c5515d56522e090f6899f38aa19 81 ProSitePatterns PS00050 Ribosomal protein L23 signature. 59 74 - T 01-11-2018 IPR001014 Ribosomal protein L23/L25, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00021820 f2da3c5515d56522e090f6899f38aa19 81 Hamap MF_01369_A 50S ribosomal protein L23 [rplW]. 2 81 24.037 T 01-11-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 AFULGI_00021820 f2da3c5515d56522e090f6899f38aa19 81 SUPERFAMILY SSF54189 3 76 5.04E-21 T 01-11-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFULGI_00019040 f1f9b3e166b2cec8f5d6359c4e9f0e71 290 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 86 97 1.7E-5 T 01-11-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 AFULGI_00019040 f1f9b3e166b2cec8f5d6359c4e9f0e71 290 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 32 47 1.7E-5 T 01-11-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 AFULGI_00019040 f1f9b3e166b2cec8f5d6359c4e9f0e71 290 Pfam PF00717 Peptidase S24-like 32 100 1.6E-11 T 01-11-2018 IPR015927 Peptidase S24/S26A/S26B/S26C AFULGI_00019040 f1f9b3e166b2cec8f5d6359c4e9f0e71 290 SUPERFAMILY SSF51306 29 100 8.11E-11 T 01-11-2018 IPR036286 LexA/Signal peptidase-like superfamily AFULGI_00019040 f1f9b3e166b2cec8f5d6359c4e9f0e71 290 TIGRFAM TIGR02228 sigpep_I_arch: signal peptidase I 7 143 4.1E-23 T 01-11-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 AFULGI_00005660 532753d265238ca60f97fbc6c0846865 73 Gene3D G3DSA:3.30.110.40 1 73 5.5E-29 T 01-11-2018 IPR036868 TusA-like domain superfamily AFULGI_00005660 532753d265238ca60f97fbc6c0846865 73 Pfam PF01206 Sulfurtransferase TusA 3 71 1.7E-25 T 01-11-2018 IPR001455 TusA-like domain AFULGI_00005660 532753d265238ca60f97fbc6c0846865 73 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 4 28 - T 01-11-2018 IPR001455 TusA-like domain AFULGI_00005660 532753d265238ca60f97fbc6c0846865 73 SUPERFAMILY SSF64307 1 71 8.5E-24 T 01-11-2018 IPR036868 TusA-like domain superfamily AFULGI_00018040 4f8468947fccd052eab4414f8d9d3635 213 SUPERFAMILY SSF89550 10 196 1.96E-33 T 01-11-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 AFULGI_00018040 4f8468947fccd052eab4414f8d9d3635 213 Pfam PF02811 PHP domain 3 98 1.3E-6 T 01-11-2018 IPR004013 PHP domain GO:0003824 AFULGI_00018040 4f8468947fccd052eab4414f8d9d3635 213 Gene3D G3DSA:3.20.20.140 1 213 5.9E-26 T 01-11-2018 AFULGI_00018040 4f8468947fccd052eab4414f8d9d3635 213 SMART SM00481 2 74 2.6E-21 T 01-11-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal AFULGI_00023060 ea3d94ae9029181f2dce0de72a441c13 324 Gene3D G3DSA:3.40.50.150 116 324 1.5E-67 T 01-11-2018 AFULGI_00023060 ea3d94ae9029181f2dce0de72a441c13 324 Pfam PF17125 N-terminal domain of 16S rRNA methyltransferase RsmF 26 111 1.4E-9 T 01-11-2018 IPR031341 Ribosomal RNA small subunit methyltransferase F, N-terminal Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 AFULGI_00023060 ea3d94ae9029181f2dce0de72a441c13 324 Gene3D G3DSA:3.30.70.3130 7 111 4.7E-28 T 01-11-2018 AFULGI_00023060 ea3d94ae9029181f2dce0de72a441c13 324 SUPERFAMILY SSF53335 13 316 7.88E-66 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFULGI_00023060 ea3d94ae9029181f2dce0de72a441c13 324 Pfam PF01189 16S rRNA methyltransferase RsmB/F 116 313 1.0E-60 T 01-11-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 AFULGI_00023060 ea3d94ae9029181f2dce0de72a441c13 324 TIGRFAM TIGR00446 nop2p: NOL1/NOP2/sun family putative RNA methylase 52 315 4.2E-128 T 01-11-2018 IPR011023 Nop2p GO:0003723|GO:0006364|GO:0008757 Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 AFULGI_00023060 ea3d94ae9029181f2dce0de72a441c13 324 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 127 137 3.7E-27 T 01-11-2018 IPR023267 RNA (C5-cytosine) methyltransferase AFULGI_00023060 ea3d94ae9029181f2dce0de72a441c13 324 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 243 259 3.7E-27 T 01-11-2018 IPR023267 RNA (C5-cytosine) methyltransferase AFULGI_00023060 ea3d94ae9029181f2dce0de72a441c13 324 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 193 205 3.7E-27 T 01-11-2018 IPR023267 RNA (C5-cytosine) methyltransferase AFULGI_00023060 ea3d94ae9029181f2dce0de72a441c13 324 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 98 112 3.7E-27 T 01-11-2018 IPR023267 RNA (C5-cytosine) methyltransferase AFULGI_00023060 ea3d94ae9029181f2dce0de72a441c13 324 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 298 315 3.7E-27 T 01-11-2018 IPR023267 RNA (C5-cytosine) methyltransferase AFULGI_00004950 da5b1e8c15191e21d7617eeda6ce1ba6 777 Gene3D G3DSA:2.30.120.10 314 379 6.6E-135 T 01-11-2018 AFULGI_00004950 da5b1e8c15191e21d7617eeda6ce1ba6 777 PIRSF PIRSF001227 8 769 2.4E-171 T 01-11-2018 IPR014395 Penicillin/GL-7-ACA/AHL acylase GO:0016811 AFULGI_00004950 da5b1e8c15191e21d7617eeda6ce1ba6 777 Gene3D G3DSA:3.60.20.10 242 756 6.6E-135 T 01-11-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFULGI_00004950 da5b1e8c15191e21d7617eeda6ce1ba6 777 Gene3D G3DSA:1.10.439.10 29 182 2.1E-46 T 01-11-2018 IPR023343 Penicillin amidase type, domain 1 GO:0016811 AFULGI_00004950 da5b1e8c15191e21d7617eeda6ce1ba6 777 Gene3D G3DSA:1.10.1400.10 546 671 6.6E-135 T 01-11-2018 AFULGI_00004950 da5b1e8c15191e21d7617eeda6ce1ba6 777 SUPERFAMILY SSF56235 50 764 1.39E-191 T 01-11-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFULGI_00004950 da5b1e8c15191e21d7617eeda6ce1ba6 777 Pfam PF01804 Penicillin amidase 50 764 3.8E-201 T 01-11-2018 IPR002692 Penicillin/GL-7-ACA/AHL/aculeacin-A acylase GO:0016787|GO:0017000 AFULGI_00019490 4973dc1356c9551261d04da7cd8c2173 97 Gene3D G3DSA:3.30.70.20 59 91 5.6E-9 T 01-11-2018 AFULGI_00019490 4973dc1356c9551261d04da7cd8c2173 97 Pfam PF14697 4Fe-4S dicluster domain 30 86 8.6E-11 T 01-11-2018 AFULGI_00019490 4973dc1356c9551261d04da7cd8c2173 97 SUPERFAMILY SSF54862 21 87 1.21E-22 T 01-11-2018 AFULGI_00019490 4973dc1356c9551261d04da7cd8c2173 97 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 69 80 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFULGI_00019490 4973dc1356c9551261d04da7cd8c2173 97 Gene3D G3DSA:3.30.70.20 8 58 8.3E-6 T 01-11-2018 AFULGI_00019490 4973dc1356c9551261d04da7cd8c2173 97 TIGRFAM TIGR02179 PorD_KorD: 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate family 10 88 2.9E-31 T 01-11-2018 IPR011898 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0051539 AFULGI_00021630 2c12bceb92bac08eaab611267abf2caf 152 Hamap MF_01371_A 50S ribosomal protein L30 [rpmD]. 1 152 82.095 T 01-11-2018 IPR005997 Ribosomal protein L30, archaeal GO:0003735|GO:0006412|GO:0015934 AFULGI_00021630 2c12bceb92bac08eaab611267abf2caf 152 Gene3D G3DSA:1.10.15.30 58 113 6.7E-55 T 01-11-2018 IPR023106 Ribosomal protein L30, central domain, archaeal type AFULGI_00021630 2c12bceb92bac08eaab611267abf2caf 152 SUPERFAMILY SSF55129 1 152 4.32E-49 T 01-11-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily AFULGI_00021630 2c12bceb92bac08eaab611267abf2caf 152 ProSitePatterns PS00634 Ribosomal protein L30 signature. 20 52 - T 01-11-2018 IPR018038 Ribosomal protein L30, conserved site AFULGI_00021630 2c12bceb92bac08eaab611267abf2caf 152 Gene3D G3DSA:3.30.1390.20 3 140 6.7E-55 T 01-11-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily AFULGI_00021630 2c12bceb92bac08eaab611267abf2caf 152 Pfam PF00327 Ribosomal protein L30p/L7e 3 52 6.4E-18 T 01-11-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain AFULGI_00021630 2c12bceb92bac08eaab611267abf2caf 152 TIGRFAM TIGR01309 uL30_arch: ribosomal protein uL30 2 152 1.7E-70 T 01-11-2018 IPR005997 Ribosomal protein L30, archaeal GO:0003735|GO:0006412|GO:0015934 AFULGI_00012530 75e64454faf4b4a9e46301d25263c093 363 SUPERFAMILY SSF54862 157 298 2.44E-15 T 01-11-2018 AFULGI_00012530 75e64454faf4b4a9e46301d25263c093 363 Pfam PF04015 Domain of unknown function (DUF362) 49 316 5.6E-39 T 01-11-2018 IPR007160 Domain of unknown function DUF362 AFULGI_00012530 75e64454faf4b4a9e46301d25263c093 363 Gene3D G3DSA:3.30.70.20 197 246 8.5E-9 T 01-11-2018 AFULGI_00012530 75e64454faf4b4a9e46301d25263c093 363 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 204 215 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFULGI_00012530 75e64454faf4b4a9e46301d25263c093 363 Pfam PF00037 4Fe-4S binding domain 197 220 1.8E-7 T 01-11-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFULGI_00013900 cd50e3f01b2c38aba66f11f513315392 168 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 3 166 1.9E-56 T 01-11-2018 IPR006286 Deglycase PfpI AFULGI_00013900 cd50e3f01b2c38aba66f11f513315392 168 Pfam PF01965 DJ-1/PfpI family 1 163 4.0E-58 T 01-11-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 AFULGI_00013900 cd50e3f01b2c38aba66f11f513315392 168 SUPERFAMILY SSF52317 1 165 8.6E-48 T 01-11-2018 IPR029062 Class I glutamine amidotransferase-like AFULGI_00013900 cd50e3f01b2c38aba66f11f513315392 168 Gene3D G3DSA:3.40.50.880 1 167 2.1E-49 T 01-11-2018 IPR029062 Class I glutamine amidotransferase-like AFULGI_00005790 d6c165e74b20b5528b713aeab8ee6436 153 Gene3D G3DSA:3.90.1010.10 1 153 9.1E-73 T 01-11-2018 AFULGI_00005790 d6c165e74b20b5528b713aeab8ee6436 153 SUPERFAMILY SSF82649 4 125 4.45E-47 T 01-11-2018 AFULGI_00005790 d6c165e74b20b5528b713aeab8ee6436 153 Pfam PF01592 NifU-like N terminal domain 1 122 2.1E-52 T 01-11-2018 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 AFULGI_00005790 d6c165e74b20b5528b713aeab8ee6436 153 TIGRFAM TIGR03419 NifU_clost: FeS cluster assembly scaffold protein NifU 2 121 3.1E-63 T 01-11-2018 IPR017787 NIF system FeS cluster assembly, NifU-like AFULGI_00001680 d6c165e74b20b5528b713aeab8ee6436 153 Gene3D G3DSA:3.90.1010.10 1 153 9.1E-73 T 01-11-2018 AFULGI_00001680 d6c165e74b20b5528b713aeab8ee6436 153 SUPERFAMILY SSF82649 4 125 4.45E-47 T 01-11-2018 AFULGI_00001680 d6c165e74b20b5528b713aeab8ee6436 153 Pfam PF01592 NifU-like N terminal domain 1 122 2.1E-52 T 01-11-2018 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 AFULGI_00001680 d6c165e74b20b5528b713aeab8ee6436 153 TIGRFAM TIGR03419 NifU_clost: FeS cluster assembly scaffold protein NifU 2 121 3.1E-63 T 01-11-2018 IPR017787 NIF system FeS cluster assembly, NifU-like AFULGI_00021470 4d5a145411ec33ad7d68d3e9e38a6e97 867 Gene3D G3DSA:2.20.25.410 813 865 9.1E-22 T 01-11-2018 AFULGI_00021470 4d5a145411ec33ad7d68d3e9e38a6e97 867 Gene3D G3DSA:2.40.40.20 300 469 4.6E-74 T 01-11-2018 AFULGI_00021470 4d5a145411ec33ad7d68d3e9e38a6e97 867 Gene3D G3DSA:1.10.274.100 480 626 1.2E-89 T 01-11-2018 AFULGI_00021470 4d5a145411ec33ad7d68d3e9e38a6e97 867 Pfam PF04997 RNA polymerase Rpb1, domain 1 4 308 3.3E-104 T 01-11-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFULGI_00021470 4d5a145411ec33ad7d68d3e9e38a6e97 867 Pfam PF04998 RNA polymerase Rpb1, domain 5 774 840 7.3E-26 T 01-11-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFULGI_00021470 4d5a145411ec33ad7d68d3e9e38a6e97 867 Gene3D G3DSA:3.30.1490.180 343 405 4.6E-74 T 01-11-2018 AFULGI_00021470 4d5a145411ec33ad7d68d3e9e38a6e97 867 SMART SM00663 200 502 3.3E-196 T 01-11-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFULGI_00021470 4d5a145411ec33ad7d68d3e9e38a6e97 867 Gene3D G3DSA:1.10.132.30 627 775 1.2E-89 T 01-11-2018 IPR038120 RNA polymerase Rpb1, funnel domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFULGI_00021470 4d5a145411ec33ad7d68d3e9e38a6e97 867 SUPERFAMILY SSF64484 2 847 0.0 T 01-11-2018 AFULGI_00021470 4d5a145411ec33ad7d68d3e9e38a6e97 867 Pfam PF00623 RNA polymerase Rpb1, domain 2 310 474 1.8E-66 T 01-11-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFULGI_00021470 4d5a145411ec33ad7d68d3e9e38a6e97 867 TIGRFAM TIGR02390 RNA_pol_rpoA1: DNA-directed RNA polymerase subunit A' 4 858 0.0 T 01-11-2018 IPR012758 DNA-directed RNA polymerase subunit A' (Rpo1N) GO:0003677|GO:0003899|GO:0006351|GO:0008270 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFULGI_00021470 4d5a145411ec33ad7d68d3e9e38a6e97 867 Pfam PF04983 RNA polymerase Rpb1, domain 3 477 633 4.0E-35 T 01-11-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFULGI_00021470 4d5a145411ec33ad7d68d3e9e38a6e97 867 Gene3D G3DSA:1.20.120.1280 223 273 2.2E-11 T 01-11-2018 AFULGI_00021470 4d5a145411ec33ad7d68d3e9e38a6e97 867 Gene3D G3DSA:1.20.120.1280 1 107 6.9E-31 T 01-11-2018 AFULGI_00021470 4d5a145411ec33ad7d68d3e9e38a6e97 867 Pfam PF05000 RNA polymerase Rpb1, domain 4 659 767 2.6E-31 T 01-11-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFULGI_00016570 c6926fff999d45d577933b9997ce2c70 795 Gene3D G3DSA:3.30.565.10 2 185 9.7E-22 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFULGI_00016570 c6926fff999d45d577933b9997ce2c70 795 SUPERFAMILY SSF55874 7 182 4.32E-20 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFULGI_00016570 c6926fff999d45d577933b9997ce2c70 795 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 26 120 1.8E-8 T 01-11-2018 AFULGI_00016100 cec8e152b4b18fab931337e58ee2f233 538 SUPERFAMILY SSF50249 156 274 7.02E-9 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold AFULGI_00016100 cec8e152b4b18fab931337e58ee2f233 538 Gene3D G3DSA:2.40.50.140 69 169 5.8E-28 T 01-11-2018 AFULGI_00016100 cec8e152b4b18fab931337e58ee2f233 538 SUPERFAMILY SSF50249 64 168 7.88E-25 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold AFULGI_00020970 f33618ac02a2481b61bb349e14b42598 238 SMART SM00382 33 214 9.6E-12 T 01-11-2018 IPR003593 AAA+ ATPase domain AFULGI_00020970 f33618ac02a2481b61bb349e14b42598 238 Gene3D G3DSA:3.40.50.300 5 237 3.2E-66 T 01-11-2018 AFULGI_00020970 f33618ac02a2481b61bb349e14b42598 238 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFULGI_00020970 f33618ac02a2481b61bb349e14b42598 238 Pfam PF00005 ABC transporter 25 170 2.0E-35 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFULGI_00020970 f33618ac02a2481b61bb349e14b42598 238 SUPERFAMILY SSF52540 7 230 1.66E-55 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00010190 7e6e01e85c2b70f000095d943daa2b9c 414 SUPERFAMILY SSF63867 337 406 6.41E-17 T 01-11-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AFULGI_00010190 7e6e01e85c2b70f000095d943daa2b9c 414 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 184 320 6.2E-35 T 01-11-2018 IPR001453 MoaB/Mog domain AFULGI_00010190 7e6e01e85c2b70f000095d943daa2b9c 414 SMART SM00852 188 324 3.1E-41 T 01-11-2018 IPR001453 MoaB/Mog domain AFULGI_00010190 7e6e01e85c2b70f000095d943daa2b9c 414 Gene3D G3DSA:2.40.340.10 334 405 4.8E-21 T 01-11-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AFULGI_00010190 7e6e01e85c2b70f000095d943daa2b9c 414 Pfam PF00994 Probable molybdopterin binding domain 188 322 5.5E-28 T 01-11-2018 IPR001453 MoaB/Mog domain AFULGI_00010190 7e6e01e85c2b70f000095d943daa2b9c 414 SUPERFAMILY SSF53218 185 328 1.96E-39 T 01-11-2018 IPR036425 MoaB/Mog-like domain superfamily AFULGI_00010190 7e6e01e85c2b70f000095d943daa2b9c 414 Pfam PF03453 MoeA N-terminal region (domain I and II) 13 175 1.0E-46 T 01-11-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AFULGI_00010190 7e6e01e85c2b70f000095d943daa2b9c 414 Gene3D G3DSA:3.90.105.10 31 182 1.2E-107 T 01-11-2018 AFULGI_00010190 7e6e01e85c2b70f000095d943daa2b9c 414 Gene3D G3DSA:2.170.190.11 53 149 1.2E-107 T 01-11-2018 AFULGI_00010190 7e6e01e85c2b70f000095d943daa2b9c 414 Gene3D G3DSA:3.40.980.10 183 323 1.2E-107 T 01-11-2018 IPR036425 MoaB/Mog-like domain superfamily AFULGI_00010190 7e6e01e85c2b70f000095d943daa2b9c 414 Pfam PF03454 MoeA C-terminal region (domain IV) 340 406 1.1E-17 T 01-11-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AFULGI_00010190 7e6e01e85c2b70f000095d943daa2b9c 414 SUPERFAMILY SSF63882 12 184 3.01E-57 T 01-11-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AFULGI_00003570 0d922742fbed5eaad1d77269e22f3277 295 SUPERFAMILY SSF53613 5 291 5.77E-75 T 01-11-2018 IPR029056 Ribokinase-like AFULGI_00003570 0d922742fbed5eaad1d77269e22f3277 295 Gene3D G3DSA:3.40.1190.20 2 294 3.1E-80 T 01-11-2018 IPR029056 Ribokinase-like AFULGI_00003570 0d922742fbed5eaad1d77269e22f3277 295 PRINTS PR00990 Ribokinase signature 33 52 3.1E-13 T 01-11-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 AFULGI_00003570 0d922742fbed5eaad1d77269e22f3277 295 PRINTS PR00990 Ribokinase signature 6 27 3.1E-13 T 01-11-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 AFULGI_00003570 0d922742fbed5eaad1d77269e22f3277 295 PRINTS PR00990 Ribokinase signature 177 192 3.1E-13 T 01-11-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 AFULGI_00003570 0d922742fbed5eaad1d77269e22f3277 295 PRINTS PR00990 Ribokinase signature 104 117 3.1E-13 T 01-11-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 AFULGI_00003570 0d922742fbed5eaad1d77269e22f3277 295 PRINTS PR00990 Ribokinase signature 215 226 3.1E-13 T 01-11-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 AFULGI_00003570 0d922742fbed5eaad1d77269e22f3277 295 Pfam PF00294 pfkB family carbohydrate kinase 7 291 2.7E-60 T 01-11-2018 IPR011611 Carbohydrate kinase PfkB AFULGI_00003570 0d922742fbed5eaad1d77269e22f3277 295 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 244 257 - T 01-11-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 AFULGI_00010050 3404bd3384d03ad44c2866403dce300c 151 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 1 149 1.7E-40 T 01-11-2018 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 AFULGI_00010050 3404bd3384d03ad44c2866403dce300c 151 Gene3D G3DSA:3.60.21.10 1 149 1.0E-32 T 01-11-2018 IPR029052 Metallo-dependent phosphatase-like AFULGI_00010050 3404bd3384d03ad44c2866403dce300c 151 SUPERFAMILY SSF56300 1 143 1.12E-24 T 01-11-2018 AFULGI_00010050 3404bd3384d03ad44c2866403dce300c 151 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 142 4.3E-24 T 01-11-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 AFULGI_00022100 58711d191141a315f662d3bd88eea2e6 589 SUPERFAMILY SSF88723 1 132 2.8E-18 T 01-11-2018 IPR029060 PIN-like domain superfamily AFULGI_00022100 58711d191141a315f662d3bd88eea2e6 589 SUPERFAMILY SSF52540 131 439 1.21E-32 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00022100 58711d191141a315f662d3bd88eea2e6 589 Gene3D G3DSA:3.40.50.1010 1 126 3.9E-34 T 01-11-2018 AFULGI_00022100 58711d191141a315f662d3bd88eea2e6 589 Pfam PF00013 KH domain 477 529 2.9E-8 T 01-11-2018 IPR004088 K Homology domain, type 1 GO:0003723 AFULGI_00022100 58711d191141a315f662d3bd88eea2e6 589 Gene3D G3DSA:3.30.1370.10 474 538 8.1E-7 T 01-11-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 AFULGI_00022100 58711d191141a315f662d3bd88eea2e6 589 Pfam PF00437 Type II/IV secretion system protein 213 372 2.3E-8 T 01-11-2018 IPR001482 Type II/IV secretion system protein AFULGI_00022100 58711d191141a315f662d3bd88eea2e6 589 SMART SM00382 258 426 1.4E-4 T 01-11-2018 IPR003593 AAA+ ATPase domain AFULGI_00022100 58711d191141a315f662d3bd88eea2e6 589 SMART SM00670 1 114 7.9E-27 T 01-11-2018 IPR002716 PIN domain AFULGI_00022100 58711d191141a315f662d3bd88eea2e6 589 Gene3D G3DSA:3.40.50.300 240 459 2.3E-18 T 01-11-2018 AFULGI_00022100 58711d191141a315f662d3bd88eea2e6 589 SMART SM00322 472 539 5.8E-5 T 01-11-2018 IPR004087 K Homology domain GO:0003676 AFULGI_00022100 58711d191141a315f662d3bd88eea2e6 589 SUPERFAMILY SSF54791 476 513 4.67E-7 T 01-11-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 AFULGI_00022100 58711d191141a315f662d3bd88eea2e6 589 Pfam PF13638 PIN domain 3 123 7.8E-5 T 01-11-2018 IPR002716 PIN domain AFULGI_00012320 e1232da74392d68e9ae63466a2dcfa51 197 SUPERFAMILY SSF52313 8 193 2.75E-58 T 01-11-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain superfamily AFULGI_00012320 e1232da74392d68e9ae63466a2dcfa51 197 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 8 184 9.641 T 01-11-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFULGI_00012320 e1232da74392d68e9ae63466a2dcfa51 197 ProSitePatterns PS00963 Ribosomal protein S2 signature 2. 115 139 - T 01-11-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 AFULGI_00012320 e1232da74392d68e9ae63466a2dcfa51 197 PRINTS PR00395 Ribosomal protein S2 signature 12 30 8.2E-26 T 01-11-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFULGI_00012320 e1232da74392d68e9ae63466a2dcfa51 197 PRINTS PR00395 Ribosomal protein S2 signature 90 107 8.2E-26 T 01-11-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFULGI_00012320 e1232da74392d68e9ae63466a2dcfa51 197 PRINTS PR00395 Ribosomal protein S2 signature 42 51 8.2E-26 T 01-11-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFULGI_00012320 e1232da74392d68e9ae63466a2dcfa51 197 PRINTS PR00395 Ribosomal protein S2 signature 153 167 8.2E-26 T 01-11-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFULGI_00012320 e1232da74392d68e9ae63466a2dcfa51 197 PRINTS PR00395 Ribosomal protein S2 signature 115 132 8.2E-26 T 01-11-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFULGI_00012320 e1232da74392d68e9ae63466a2dcfa51 197 PRINTS PR00395 Ribosomal protein S2 signature 132 143 8.2E-26 T 01-11-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFULGI_00012320 e1232da74392d68e9ae63466a2dcfa51 197 Gene3D G3DSA:3.40.50.10490 11 197 1.3E-77 T 01-11-2018 AFULGI_00012320 e1232da74392d68e9ae63466a2dcfa51 197 TIGRFAM TIGR01012 uS2_euk_arch: ribosomal protein uS2 7 196 3.0E-95 T 01-11-2018 IPR005707 Ribosomal protein S2, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00012320 e1232da74392d68e9ae63466a2dcfa51 197 Pfam PF00318 Ribosomal protein S2 16 106 6.2E-13 T 01-11-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFULGI_00012320 e1232da74392d68e9ae63466a2dcfa51 197 Pfam PF00318 Ribosomal protein S2 113 179 7.9E-15 T 01-11-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFULGI_00012320 e1232da74392d68e9ae63466a2dcfa51 197 Hamap MF_00291_A 30S ribosomal protein S2 [rpsB]. 4 197 48.909 T 01-11-2018 IPR023454 Ribosomal protein S2, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFULGI_00016430 8b4f056915c7f9d631513ddd79294138 129 Gene3D G3DSA:2.40.70.10 8 129 6.4E-10 T 01-11-2018 IPR021109 Aspartic peptidase domain superfamily AFULGI_00016430 8b4f056915c7f9d631513ddd79294138 129 Pfam PF13650 Aspartyl protease 23 86 2.9E-5 T 01-11-2018 AFULGI_00016430 8b4f056915c7f9d631513ddd79294138 129 SUPERFAMILY SSF50630 28 114 3.18E-8 T 01-11-2018 IPR021109 Aspartic peptidase domain superfamily AFULGI_00026340 bdef8a0f74e103c4a61afb78f125bf05 269 TIGRFAM TIGR00417 speE: spermidine synthase 3 260 7.9E-110 T 01-11-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 AFULGI_00026340 bdef8a0f74e103c4a61afb78f125bf05 269 Gene3D G3DSA:2.30.140.10 1 51 2.4E-17 T 01-11-2018 IPR037163 Spermidine synthase, tetramerisation domain superfamily KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 AFULGI_00026340 bdef8a0f74e103c4a61afb78f125bf05 269 Pfam PF17284 Spermidine synthase tetramerisation domain 2 52 4.0E-19 T 01-11-2018 IPR035246 Spermidine synthase, tetramerisation domain KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 AFULGI_00026340 bdef8a0f74e103c4a61afb78f125bf05 269 SUPERFAMILY SSF53335 3 265 9.36E-59 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFULGI_00026340 bdef8a0f74e103c4a61afb78f125bf05 269 Gene3D G3DSA:3.40.50.150 52 267 2.2E-57 T 01-11-2018 AFULGI_00026340 bdef8a0f74e103c4a61afb78f125bf05 269 Pfam PF01564 Spermine/spermidine synthase domain 56 227 9.9E-57 T 01-11-2018 AFULGI_00026340 bdef8a0f74e103c4a61afb78f125bf05 269 ProSitePatterns PS01330 Polyamine biosynthesis (PABS) domain signature. 76 89 - T 01-11-2018 IPR030373 Polyamine biosynthesis domain, conserved site KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 AFULGI_00026340 bdef8a0f74e103c4a61afb78f125bf05 269 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 2 266 34.898 T 01-11-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 AFULGI_00022890 2a75d8226ccc04fdf10d02128a275a23 342 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 2 342 5.7E-119 T 01-11-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 AFULGI_00022890 2a75d8226ccc04fdf10d02128a275a23 342 SUPERFAMILY SSF53383 21 342 1.28E-80 T 01-11-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFULGI_00022890 2a75d8226ccc04fdf10d02128a275a23 342 Gene3D G3DSA:3.40.640.10 37 251 3.1E-100 T 01-11-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFULGI_00022890 2a75d8226ccc04fdf10d02128a275a23 342 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 1 342 52.829 T 01-11-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 AFULGI_00022890 2a75d8226ccc04fdf10d02128a275a23 342 Gene3D G3DSA:3.90.1150.10 25 340 3.1E-100 T 01-11-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFULGI_00022890 2a75d8226ccc04fdf10d02128a275a23 342 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 203 216 - T 01-11-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 AFULGI_00022890 2a75d8226ccc04fdf10d02128a275a23 342 Pfam PF00155 Aminotransferase class I and II 24 339 1.6E-49 T 01-11-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 AFULGI_00013520 539846e633d3cb2f8095dd5f76323b8f 179 Gene3D G3DSA:3.40.630.30 19 179 7.1E-30 T 01-11-2018 AFULGI_00013520 539846e633d3cb2f8095dd5f76323b8f 179 SUPERFAMILY SSF55729 25 165 4.8E-31 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase AFULGI_00013520 539846e633d3cb2f8095dd5f76323b8f 179 Pfam PF00583 Acetyltransferase (GNAT) family 63 158 4.4E-18 T 01-11-2018 IPR000182 GNAT domain AFULGI_00023790 ffbd6106003c77e27c1038b0d3038960 213 Pfam PF01914 MarC family integral membrane protein 8 207 1.9E-70 T 01-11-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 AFULGI_00023790 ffbd6106003c77e27c1038b0d3038960 213 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 1 204 2.7E-84 T 01-11-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 AFULGI_00016880 ec25471ac3ebd3fdde8ba654333d4553 572 Pfam PF07510 Protein of unknown function (DUF1524) 444 546 5.6E-6 T 01-11-2018 IPR011089 Domain of unknown function DUF1524 AFULGI_00016880 ec25471ac3ebd3fdde8ba654333d4553 572 Pfam PF03235 Protein of unknown function DUF262 29 241 8.6E-27 T 01-11-2018 IPR004919 Domain of unknown function DUF262 AFULGI_00019500 f32bc0129738946c0e02b7454f502927 391 Gene3D G3DSA:3.40.50.920 254 381 5.1E-36 T 01-11-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 AFULGI_00019500 f32bc0129738946c0e02b7454f502927 391 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 15 238 2.4E-79 T 01-11-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 AFULGI_00019500 f32bc0129738946c0e02b7454f502927 391 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 262 357 8.7E-29 T 01-11-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II AFULGI_00019500 f32bc0129738946c0e02b7454f502927 391 SUPERFAMILY SSF52922 257 372 1.57E-31 T 01-11-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 AFULGI_00019500 f32bc0129738946c0e02b7454f502927 391 SUPERFAMILY SSF52518 3 248 1.22E-65 T 01-11-2018 IPR029061 Thiamin diphosphate-binding fold AFULGI_00019500 f32bc0129738946c0e02b7454f502927 391 Gene3D G3DSA:3.40.50.970 1 250 1.8E-96 T 01-11-2018 AFULGI_00012970 fafbd8263a00124ce45930f624fa93bd 252 SMART SM00882 7 214 2.0E-14 T 01-11-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 AFULGI_00012970 fafbd8263a00124ce45930f624fa93bd 252 Pfam PF01144 Coenzyme A transferase 12 213 8.6E-23 T 01-11-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 AFULGI_00012970 fafbd8263a00124ce45930f624fa93bd 252 Gene3D G3DSA:3.40.1080.10 1 251 1.7E-77 T 01-11-2018 AFULGI_00012970 fafbd8263a00124ce45930f624fa93bd 252 SUPERFAMILY SSF100950 2 248 7.33E-58 T 01-11-2018 IPR037171 NagB/RpiA transferase-like AFULGI_00005170 67b8f650415e5039ea9ea26dc77872db 400 SUPERFAMILY SSF55103 259 384 3.11E-6 T 01-11-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 AFULGI_00005170 67b8f650415e5039ea9ea26dc77872db 400 Pfam PF01565 FAD binding domain 43 170 2.4E-32 T 01-11-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 AFULGI_00005170 67b8f650415e5039ea9ea26dc77872db 400 Gene3D G3DSA:3.30.465.40 13 223 3.8E-40 T 01-11-2018 AFULGI_00005170 67b8f650415e5039ea9ea26dc77872db 400 SUPERFAMILY SSF56176 18 203 8.41E-38 T 01-11-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 AFULGI_00000920 a4195f6e3f21aac0b94767d1bca72786 335 Gene3D G3DSA:3.40.190.10 106 276 2.8E-142 T 01-11-2018 AFULGI_00000920 a4195f6e3f21aac0b94767d1bca72786 335 Gene3D G3DSA:3.40.190.10 28 321 2.8E-142 T 01-11-2018 AFULGI_00000920 a4195f6e3f21aac0b94767d1bca72786 335 TIGRFAM TIGR03730 tungstate_WtpA: tungstate ABC transporter binding protein WtpA 27 299 1.2E-130 T 01-11-2018 IPR022498 Tungstate ABC transporter, substrate-binding protein WtpA GO:1901359 AFULGI_00000920 a4195f6e3f21aac0b94767d1bca72786 335 SUPERFAMILY SSF53850 26 322 4.08E-68 T 01-11-2018 AFULGI_00000920 a4195f6e3f21aac0b94767d1bca72786 335 Pfam PF13531 Bacterial extracellular solute-binding protein 28 312 5.6E-38 T 01-11-2018 AFULGI_00019810 e834663abe07f1bce5b4aafe820f4aa6 264 Gene3D G3DSA:3.30.70.580 1 94 8.4E-26 T 01-11-2018 AFULGI_00019810 e834663abe07f1bce5b4aafe820f4aa6 264 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 1 222 31.751 T 01-11-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFULGI_00019810 e834663abe07f1bce5b4aafe820f4aa6 264 Pfam PF01416 tRNA pseudouridine synthase 121 223 4.6E-27 T 01-11-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFULGI_00019810 e834663abe07f1bce5b4aafe820f4aa6 264 SUPERFAMILY SSF55120 1 230 8.49E-71 T 01-11-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFULGI_00019810 e834663abe07f1bce5b4aafe820f4aa6 264 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 2 217 1.7E-71 T 01-11-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFULGI_00019810 e834663abe07f1bce5b4aafe820f4aa6 264 Gene3D G3DSA:3.30.70.660 95 221 1.3E-30 T 01-11-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0003723|GO:0009982 AFULGI_00019810 e834663abe07f1bce5b4aafe820f4aa6 264 PIRSF PIRSF001430 1 238 7.9E-72 T 01-11-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFULGI_00010280 154c2ed84bc6aede84382aaabf4b22b8 106 Pfam PF00338 Ribosomal protein S10p/S20e 9 102 6.5E-27 T 01-11-2018 IPR027486 Ribosomal protein S10 domain AFULGI_00010280 154c2ed84bc6aede84382aaabf4b22b8 106 SMART SM01403 9 103 3.4E-41 T 01-11-2018 IPR027486 Ribosomal protein S10 domain AFULGI_00010280 154c2ed84bc6aede84382aaabf4b22b8 106 ProSitePatterns PS00361 Ribosomal protein S10 signature. 31 46 - T 01-11-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00010280 154c2ed84bc6aede84382aaabf4b22b8 106 PRINTS PR00971 Ribosomal protein S10 family signature 64 78 7.3E-16 T 01-11-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00010280 154c2ed84bc6aede84382aaabf4b22b8 106 PRINTS PR00971 Ribosomal protein S10 family signature 42 57 7.3E-16 T 01-11-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00010280 154c2ed84bc6aede84382aaabf4b22b8 106 PRINTS PR00971 Ribosomal protein S10 family signature 7 20 7.3E-16 T 01-11-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00010280 154c2ed84bc6aede84382aaabf4b22b8 106 SUPERFAMILY SSF54999 7 103 1.57E-29 T 01-11-2018 IPR036838 Ribosomal protein S10 domain superfamily AFULGI_00010280 154c2ed84bc6aede84382aaabf4b22b8 106 TIGRFAM TIGR01046 uS10_euk_arch: ribosomal protein uS10 7 103 9.4E-52 T 01-11-2018 IPR005729 Ribosomal protein S10, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00010280 154c2ed84bc6aede84382aaabf4b22b8 106 Gene3D G3DSA:3.30.70.600 3 104 1.6E-33 T 01-11-2018 IPR036838 Ribosomal protein S10 domain superfamily AFULGI_00010280 154c2ed84bc6aede84382aaabf4b22b8 106 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 5 104 24.939 T 01-11-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00023020 c7ee1cf1758d190add79ee4bb79f8c87 281 Pfam PF01040 UbiA prenyltransferase family 20 265 3.9E-52 T 01-11-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 AFULGI_00023020 c7ee1cf1758d190add79ee4bb79f8c87 281 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 3 280 16.688 T 01-11-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 AFULGI_00023020 c7ee1cf1758d190add79ee4bb79f8c87 281 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 5 277 8.1E-87 T 01-11-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 AFULGI_00023020 c7ee1cf1758d190add79ee4bb79f8c87 281 Gene3D G3DSA:1.10.357.140 10 175 1.0E-16 T 01-11-2018 AFULGI_00023020 c7ee1cf1758d190add79ee4bb79f8c87 281 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 56 78 - T 01-11-2018 IPR030470 UbiA prenyltransferase conserved site AFULGI_00026160 e6b8824b2064445386d620b7e7577c2c 518 Pfam PF04055 Radical SAM superfamily 104 262 3.1E-25 T 01-11-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFULGI_00026160 e6b8824b2064445386d620b7e7577c2c 518 SUPERFAMILY SSF102114 89 377 1.7E-50 T 01-11-2018 AFULGI_00026160 e6b8824b2064445386d620b7e7577c2c 518 Pfam PF13394 4Fe-4S single cluster domain 105 188 8.6E-7 T 01-11-2018 AFULGI_00026160 e6b8824b2064445386d620b7e7577c2c 518 Gene3D G3DSA:3.20.20.70 88 316 1.3E-37 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFULGI_00008510 e9a12675f1a0c0827d03628b8405cbba 625 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 523 623 4.1E-19 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFULGI_00008510 e9a12675f1a0c0827d03628b8405cbba 625 Pfam PF08447 PAS fold 328 399 8.9E-15 T 01-11-2018 IPR013655 PAS fold-3 GO:0005515 AFULGI_00008510 e9a12675f1a0c0827d03628b8405cbba 625 SMART SM00091 182 247 5.9E-13 T 01-11-2018 IPR000014 PAS domain AFULGI_00008510 e9a12675f1a0c0827d03628b8405cbba 625 SMART SM00091 304 369 2.1E-10 T 01-11-2018 IPR000014 PAS domain AFULGI_00008510 e9a12675f1a0c0827d03628b8405cbba 625 SUPERFAMILY SSF55874 491 623 2.62E-26 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFULGI_00008510 e9a12675f1a0c0827d03628b8405cbba 625 SMART SM00388 428 489 0.0087 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFULGI_00008510 e9a12675f1a0c0827d03628b8405cbba 625 SUPERFAMILY SSF55785 289 413 1.1E-28 T 01-11-2018 IPR035965 PAS domain superfamily AFULGI_00008510 e9a12675f1a0c0827d03628b8405cbba 625 SUPERFAMILY SSF55785 167 290 1.13E-30 T 01-11-2018 IPR035965 PAS domain superfamily AFULGI_00008510 e9a12675f1a0c0827d03628b8405cbba 625 SMART SM00086 252 292 0.002 T 01-11-2018 IPR001610 PAC motif AFULGI_00008510 e9a12675f1a0c0827d03628b8405cbba 625 SMART SM00086 375 415 0.0045 T 01-11-2018 IPR001610 PAC motif AFULGI_00008510 e9a12675f1a0c0827d03628b8405cbba 625 SMART SM00387 520 624 1.4E-24 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFULGI_00008510 e9a12675f1a0c0827d03628b8405cbba 625 Pfam PF13426 PAS domain 193 291 7.9E-17 T 01-11-2018 IPR000014 PAS domain AFULGI_00008510 e9a12675f1a0c0827d03628b8405cbba 625 PRINTS PR00344 Bacterial sensor protein C-terminal signature 610 623 5.2E-8 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFULGI_00008510 e9a12675f1a0c0827d03628b8405cbba 625 PRINTS PR00344 Bacterial sensor protein C-terminal signature 586 604 5.2E-8 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFULGI_00008510 e9a12675f1a0c0827d03628b8405cbba 625 PRINTS PR00344 Bacterial sensor protein C-terminal signature 556 570 5.2E-8 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFULGI_00008510 e9a12675f1a0c0827d03628b8405cbba 625 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 179 299 4.9E-36 T 01-11-2018 IPR000014 PAS domain AFULGI_00008510 e9a12675f1a0c0827d03628b8405cbba 625 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 300 422 8.3E-33 T 01-11-2018 IPR000014 PAS domain AFULGI_00008510 e9a12675f1a0c0827d03628b8405cbba 625 Gene3D G3DSA:3.30.450.20 166 290 8.1E-31 T 01-11-2018 AFULGI_00008510 e9a12675f1a0c0827d03628b8405cbba 625 Gene3D G3DSA:3.30.450.20 291 413 5.4E-27 T 01-11-2018 AFULGI_00008510 e9a12675f1a0c0827d03628b8405cbba 625 Gene3D G3DSA:3.30.565.10 488 622 1.3E-28 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFULGI_00008510 e9a12675f1a0c0827d03628b8405cbba 625 Gene3D G3DSA:1.10.287.130 438 486 1.3E-28 T 01-11-2018 AFULGI_00025800 00815dc52ad390fbd6e93a60886d4fde 264 Gene3D G3DSA:3.30.1360.10 6 256 8.5E-86 T 01-11-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFULGI_00025800 00815dc52ad390fbd6e93a60886d4fde 264 Pfam PF13187 4Fe-4S dicluster domain 172 218 2.1E-8 T 01-11-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFULGI_00025800 00815dc52ad390fbd6e93a60886d4fde 264 ProSitePatterns PS00446 RNA polymerases D / 30 to 40 Kd subunits signature. 28 68 - T 01-11-2018 IPR001514 DNA-directed RNA polymerase, 30-40kDa subunit, conserved site GO:0003677|GO:0003899|GO:0006351 AFULGI_00025800 00815dc52ad390fbd6e93a60886d4fde 264 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 16 252 1.0E-14 T 01-11-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFULGI_00025800 00815dc52ad390fbd6e93a60886d4fde 264 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 173 184 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFULGI_00025800 00815dc52ad390fbd6e93a60886d4fde 264 SUPERFAMILY SSF56553 39 155 7.85E-30 T 01-11-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFULGI_00025800 00815dc52ad390fbd6e93a60886d4fde 264 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 46 154 3.0E-27 T 01-11-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFULGI_00025800 00815dc52ad390fbd6e93a60886d4fde 264 SMART SM00662 14 259 3.4E-102 T 01-11-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFULGI_00025800 00815dc52ad390fbd6e93a60886d4fde 264 Gene3D G3DSA:3.30.70.3110 164 223 8.5E-86 T 01-11-2018 AFULGI_00025800 00815dc52ad390fbd6e93a60886d4fde 264 Gene3D G3DSA:2.170.120.12 40 153 8.5E-86 T 01-11-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFULGI_00025800 00815dc52ad390fbd6e93a60886d4fde 264 Hamap MF_00320 DNA-directed RNA polymerase subunit D [rpoD]. 3 262 36.804 T 01-11-2018 IPR022842 DNA-directed RNA polymerase subunit D (Rpo3) GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFULGI_00025800 00815dc52ad390fbd6e93a60886d4fde 264 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 203 214 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFULGI_00025800 00815dc52ad390fbd6e93a60886d4fde 264 SUPERFAMILY SSF55257 3 262 5.81E-29 T 01-11-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFULGI_00019570 8f409d8fdb931ae2aed6a21cb8c1c41e 957 Gene3D G3DSA:3.40.50.300 418 666 1.2E-39 T 01-11-2018 AFULGI_00019570 8f409d8fdb931ae2aed6a21cb8c1c41e 957 TIGRFAM TIGR00348 hsdR: type I site-specific deoxyribonuclease, HsdR family 6 658 1.8E-246 T 01-11-2018 IPR004473 Restriction endonuclease, type I, HsdR GO:0003677|GO:0005524|GO:0009035|GO:0009307 AFULGI_00019570 8f409d8fdb931ae2aed6a21cb8c1c41e 957 SUPERFAMILY SSF52540 190 451 2.59E-25 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00019570 8f409d8fdb931ae2aed6a21cb8c1c41e 957 Pfam PF04851 Type III restriction enzyme, res subunit 222 394 1.6E-19 T 01-11-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 AFULGI_00019570 8f409d8fdb931ae2aed6a21cb8c1c41e 957 Gene3D G3DSA:3.90.1570.50 76 170 2.4E-13 T 01-11-2018 AFULGI_00019570 8f409d8fdb931ae2aed6a21cb8c1c41e 957 SMART SM00487 218 430 5.1E-12 T 01-11-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFULGI_00019570 8f409d8fdb931ae2aed6a21cb8c1c41e 957 Gene3D G3DSA:3.40.50.300 221 417 3.8E-43 T 01-11-2018 AFULGI_00019570 8f409d8fdb931ae2aed6a21cb8c1c41e 957 SUPERFAMILY SSF52540 249 623 8.69E-5 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00019570 8f409d8fdb931ae2aed6a21cb8c1c41e 957 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 4 179 1.4E-31 T 01-11-2018 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 AFULGI_00021750 077de560915e53e5388ddf5e27e9ff4d 111 Pfam PF00366 Ribosomal protein S17 35 102 3.1E-22 T 01-11-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFULGI_00021750 077de560915e53e5388ddf5e27e9ff4d 111 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 33 100 7.0E-33 T 01-11-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFULGI_00021750 077de560915e53e5388ddf5e27e9ff4d 111 SUPERFAMILY SSF50249 29 108 8.14E-23 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold AFULGI_00021750 077de560915e53e5388ddf5e27e9ff4d 111 TIGRFAM TIGR03630 uS17_arch: ribosomal protein uS17 4 103 4.8E-46 T 01-11-2018 IPR028333 Ribosomal protein S17, archaeal/eukaryotic Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00021750 077de560915e53e5388ddf5e27e9ff4d 111 ProSitePatterns PS00056 Ribosomal protein S17 signature. 81 93 - T 01-11-2018 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00021750 077de560915e53e5388ddf5e27e9ff4d 111 Hamap MF_01345_A 30S ribosomal protein S17 [rpsQ]. 2 105 33.387 T 01-11-2018 IPR019978 Ribosomal protein S17, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFULGI_00021750 077de560915e53e5388ddf5e27e9ff4d 111 PRINTS PR00973 Ribosomal protein S17 family signature 81 91 6.2E-12 T 01-11-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFULGI_00021750 077de560915e53e5388ddf5e27e9ff4d 111 PRINTS PR00973 Ribosomal protein S17 family signature 91 98 6.2E-12 T 01-11-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFULGI_00021750 077de560915e53e5388ddf5e27e9ff4d 111 PRINTS PR00973 Ribosomal protein S17 family signature 48 71 6.2E-12 T 01-11-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFULGI_00021750 077de560915e53e5388ddf5e27e9ff4d 111 Gene3D G3DSA:2.40.50.1000 1 111 9.0E-37 T 01-11-2018 AFULGI_00004450 74b4f27d8afc0d7a44e03f360a20d70e 225 Pfam PF04055 Radical SAM superfamily 26 172 1.1E-10 T 01-11-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFULGI_00004450 74b4f27d8afc0d7a44e03f360a20d70e 225 Hamap MF_00917 7-carboxy-7-deazaguanine synthase [queE]. 3 225 38.369 T 01-11-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 AFULGI_00004450 74b4f27d8afc0d7a44e03f360a20d70e 225 SUPERFAMILY SSF102114 25 192 1.7E-11 T 01-11-2018 AFULGI_00004450 74b4f27d8afc0d7a44e03f360a20d70e 225 PIRSF PIRSF000370 1 225 2.3E-33 T 01-11-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 AFULGI_00004450 74b4f27d8afc0d7a44e03f360a20d70e 225 Pfam PF13353 4Fe-4S single cluster domain 13 96 1.6E-8 T 01-11-2018 AFULGI_00004450 74b4f27d8afc0d7a44e03f360a20d70e 225 Gene3D G3DSA:3.20.20.70 4 225 6.7E-29 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFULGI_00010940 87cb225455da831db01efceb046192b3 247 Hamap MF_00193 NH(3)-dependent NAD(+) synthetase [nadE]. 2 241 54.218 T 01-11-2018 IPR022926 NH(3)-dependent NAD(+) synthetase GO:0008795|GO:0009435 KEGG: 00760+6.3.1.5 AFULGI_00010940 87cb225455da831db01efceb046192b3 247 Gene3D G3DSA:3.40.50.620 1 243 1.1E-87 T 01-11-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFULGI_00010940 87cb225455da831db01efceb046192b3 247 Pfam PF02540 NAD synthase 7 238 3.9E-99 T 01-11-2018 IPR022310 NAD/GMP synthase AFULGI_00010940 87cb225455da831db01efceb046192b3 247 SUPERFAMILY SSF52402 2 240 2.19E-77 T 01-11-2018 AFULGI_00010940 87cb225455da831db01efceb046192b3 247 TIGRFAM TIGR00552 nadE: NAD+ synthetase 3 243 8.8E-103 T 01-11-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 AFULGI_00020540 f3cc85b4f958c13df4284b01120eb75d 396 Pfam PF02589 LUD domain 55 282 7.5E-36 T 01-11-2018 IPR003741 LUD domain AFULGI_00020540 f3cc85b4f958c13df4284b01120eb75d 396 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 341 352 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFULGI_00020540 f3cc85b4f958c13df4284b01120eb75d 396 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 300 311 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFULGI_00020540 f3cc85b4f958c13df4284b01120eb75d 396 Pfam PF13187 4Fe-4S dicluster domain 299 353 1.1E-7 T 01-11-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFULGI_00020540 f3cc85b4f958c13df4284b01120eb75d 396 SUPERFAMILY SSF46548 292 366 9.16E-14 T 01-11-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 AFULGI_00020540 f3cc85b4f958c13df4284b01120eb75d 396 SUPERFAMILY SSF100950 51 283 1.3E-22 T 01-11-2018 IPR037171 NagB/RpiA transferase-like AFULGI_00020540 f3cc85b4f958c13df4284b01120eb75d 396 Gene3D G3DSA:1.10.1060.10 289 367 4.8E-8 T 01-11-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 AFULGI_00020540 f3cc85b4f958c13df4284b01120eb75d 396 Gene3D G3DSA:3.40.50.10420 103 282 2.0E-10 T 01-11-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily AFULGI_00004810 52cd2a79a5051ee4458d27790f16df73 804 Pfam PF00122 E1-E2 ATPase 222 400 2.4E-58 T 01-11-2018 AFULGI_00004810 52cd2a79a5051ee4458d27790f16df73 804 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 140 726 9.9E-184 T 01-11-2018 AFULGI_00004810 52cd2a79a5051ee4458d27790f16df73 804 Gene3D G3DSA:2.70.150.20 214 326 1.3E-45 T 01-11-2018 AFULGI_00004810 52cd2a79a5051ee4458d27790f16df73 804 SUPERFAMILY SSF55008 14 82 4.71E-20 T 01-11-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 AFULGI_00004810 52cd2a79a5051ee4458d27790f16df73 804 Pfam PF00403 Heavy-metal-associated domain 19 79 1.0E-14 T 01-11-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 AFULGI_00004810 52cd2a79a5051ee4458d27790f16df73 804 Pfam PF00403 Heavy-metal-associated domain 744 799 5.8E-5 T 01-11-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 AFULGI_00004810 52cd2a79a5051ee4458d27790f16df73 804 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 422 436 4.6E-27 T 01-11-2018 AFULGI_00004810 52cd2a79a5051ee4458d27790f16df73 804 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 542 553 4.6E-27 T 01-11-2018 AFULGI_00004810 52cd2a79a5051ee4458d27790f16df73 804 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 564 574 4.6E-27 T 01-11-2018 AFULGI_00004810 52cd2a79a5051ee4458d27790f16df73 804 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 639 651 4.6E-27 T 01-11-2018 AFULGI_00004810 52cd2a79a5051ee4458d27790f16df73 804 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 271 285 4.6E-27 T 01-11-2018 AFULGI_00004810 52cd2a79a5051ee4458d27790f16df73 804 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 616 635 4.6E-27 T 01-11-2018 AFULGI_00004810 52cd2a79a5051ee4458d27790f16df73 804 SUPERFAMILY SSF81653 225 321 3.27E-30 T 01-11-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 AFULGI_00004810 52cd2a79a5051ee4458d27790f16df73 804 Gene3D G3DSA:3.40.1110.10 433 549 1.1E-109 T 01-11-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 AFULGI_00004810 52cd2a79a5051ee4458d27790f16df73 804 Pfam PF00702 haloacid dehalogenase-like hydrolase 419 630 2.1E-43 T 01-11-2018 AFULGI_00004810 52cd2a79a5051ee4458d27790f16df73 804 Gene3D G3DSA:3.30.70.100 15 81 1.6E-21 T 01-11-2018 AFULGI_00004810 52cd2a79a5051ee4458d27790f16df73 804 ProSitePatterns PS01047 Heavy-metal-associated domain. 746 774 - T 01-11-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 AFULGI_00004810 52cd2a79a5051ee4458d27790f16df73 804 SUPERFAMILY SSF81665 187 689 1.96E-15 T 01-11-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 AFULGI_00004810 52cd2a79a5051ee4458d27790f16df73 804 SUPERFAMILY SSF55008 741 802 1.83E-9 T 01-11-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 AFULGI_00004810 52cd2a79a5051ee4458d27790f16df73 804 Gene3D G3DSA:3.40.50.1000 403 668 1.1E-109 T 01-11-2018 IPR023214 HAD superfamily AFULGI_00004810 52cd2a79a5051ee4458d27790f16df73 804 SUPERFAMILY SSF56784 421 723 3.79E-58 T 01-11-2018 IPR036412 HAD-like superfamily AFULGI_00004810 52cd2a79a5051ee4458d27790f16df73 804 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 194 694 1.2E-100 T 01-11-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 AFULGI_00004810 52cd2a79a5051ee4458d27790f16df73 804 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 19 81 2.8E-18 T 01-11-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 AFULGI_00004810 52cd2a79a5051ee4458d27790f16df73 804 Gene3D G3DSA:3.30.70.100 741 804 7.3E-16 T 01-11-2018 AFULGI_00004810 52cd2a79a5051ee4458d27790f16df73 804 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 424 430 - T 01-11-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 AFULGI_00004810 52cd2a79a5051ee4458d27790f16df73 804 PRINTS PR00943 Copper-transporting ATPase signature 405 420 1.0E-9 T 01-11-2018 AFULGI_00004810 52cd2a79a5051ee4458d27790f16df73 804 PRINTS PR00943 Copper-transporting ATPase signature 191 210 1.0E-9 T 01-11-2018 AFULGI_00004810 52cd2a79a5051ee4458d27790f16df73 804 PRINTS PR00943 Copper-transporting ATPase signature 143 162 1.0E-9 T 01-11-2018 AFULGI_00004810 52cd2a79a5051ee4458d27790f16df73 804 PRINTS PR00943 Copper-transporting ATPase signature 594 611 1.0E-9 T 01-11-2018 AFULGI_00004810 52cd2a79a5051ee4458d27790f16df73 804 PRINTS PR00943 Copper-transporting ATPase signature 650 664 1.0E-9 T 01-11-2018 AFULGI_00004810 52cd2a79a5051ee4458d27790f16df73 804 PRINTS PR00943 Copper-transporting ATPase signature 32 46 1.0E-9 T 01-11-2018 AFULGI_00004810 52cd2a79a5051ee4458d27790f16df73 804 PRINTS PR00943 Copper-transporting ATPase signature 344 358 1.0E-9 T 01-11-2018 AFULGI_00004810 52cd2a79a5051ee4458d27790f16df73 804 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 158 725 1.1E-191 T 01-11-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 AFULGI_00007720 e4eaed1295d2f282ebf666a625bf0686 585 SUPERFAMILY SSF54292 2 95 1.05E-21 T 01-11-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 AFULGI_00007720 e4eaed1295d2f282ebf666a625bf0686 585 Gene3D G3DSA:3.10.20.30 3 93 2.4E-24 T 01-11-2018 IPR012675 Beta-grasp domain superfamily AFULGI_00007720 e4eaed1295d2f282ebf666a625bf0686 585 Pfam PF14574 Domain of unknown function (DUF4445) 164 568 2.3E-136 T 01-11-2018 IPR027980 Protein of unknown function DUF4445 AFULGI_00007720 e4eaed1295d2f282ebf666a625bf0686 585 Gene3D G3DSA:3.30.420.480 162 337 9.9E-52 T 01-11-2018 AFULGI_00007720 e4eaed1295d2f282ebf666a625bf0686 585 SUPERFAMILY SSF53067 166 504 6.31E-6 T 01-11-2018 AFULGI_00007720 e4eaed1295d2f282ebf666a625bf0686 585 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 9 80 1.0E-13 T 01-11-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 AFULGI_00011750 4f5a2d7e3dde4c8ab50835d6c8fc8096 92 Gene3D G3DSA:3.30.2310.20 3 92 5.1E-18 T 01-11-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily AFULGI_00011750 4f5a2d7e3dde4c8ab50835d6c8fc8096 92 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 5 85 3.4E-7 T 01-11-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family AFULGI_00011750 4f5a2d7e3dde4c8ab50835d6c8fc8096 92 SUPERFAMILY SSF143011 1 91 2.62E-17 T 01-11-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily AFULGI_00003390 ff616794041709ba51b1d58f41c46544 598 SMART SM00790 4 207 2.7E-118 T 01-11-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 AFULGI_00003390 ff616794041709ba51b1d58f41c46544 598 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 226 594 4.9E-107 T 01-11-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 AFULGI_00003390 ff616794041709ba51b1d58f41c46544 598 Gene3D G3DSA:3.60.9.10 1 208 2.6E-80 T 01-11-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily AFULGI_00003390 ff616794041709ba51b1d58f41c46544 598 SUPERFAMILY SSF56228 1 207 6.93E-72 T 01-11-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily AFULGI_00003390 ff616794041709ba51b1d58f41c46544 598 SUPERFAMILY SSF48310 217 597 7.06E-110 T 01-11-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 AFULGI_00003390 ff616794041709ba51b1d58f41c46544 598 Gene3D G3DSA:1.10.569.10 245 422 5.4E-107 T 01-11-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 AFULGI_00003390 ff616794041709ba51b1d58f41c46544 598 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 6 203 1.4E-74 T 01-11-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 AFULGI_00003390 ff616794041709ba51b1d58f41c46544 598 Gene3D G3DSA:1.10.599.10 243 594 5.4E-107 T 01-11-2018 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 AFULGI_00013390 959d8612aa64ff845d212e4a28dbb47d 418 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 231 267 - T 01-11-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFULGI_00013390 959d8612aa64ff845d212e4a28dbb47d 418 Gene3D G3DSA:3.90.1150.10 9 413 3.5E-169 T 01-11-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFULGI_00013390 959d8612aa64ff845d212e4a28dbb47d 418 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 5 417 7.6E-192 T 01-11-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 AFULGI_00013390 959d8612aa64ff845d212e4a28dbb47d 418 SUPERFAMILY SSF53383 2 417 6.67E-122 T 01-11-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFULGI_00013390 959d8612aa64ff845d212e4a28dbb47d 418 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 5 418 93.271 T 01-11-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 AFULGI_00013390 959d8612aa64ff845d212e4a28dbb47d 418 Pfam PF00202 Aminotransferase class-III 32 413 3.5E-66 T 01-11-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFULGI_00013390 959d8612aa64ff845d212e4a28dbb47d 418 Gene3D G3DSA:3.40.640.10 68 314 3.5E-169 T 01-11-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFULGI_00003260 822f7ca12e285b7c953b27e56fef1424 357 Pfam PF13439 Glycosyltransferase Family 4 16 179 4.2E-18 T 01-11-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 AFULGI_00003260 822f7ca12e285b7c953b27e56fef1424 357 Gene3D G3DSA:3.40.50.2000 2 193 1.4E-19 T 01-11-2018 AFULGI_00003260 822f7ca12e285b7c953b27e56fef1424 357 SUPERFAMILY SSF53756 6 352 3.4E-70 T 01-11-2018 AFULGI_00003260 822f7ca12e285b7c953b27e56fef1424 357 Gene3D G3DSA:3.40.50.2000 194 343 1.1E-32 T 01-11-2018 AFULGI_00003260 822f7ca12e285b7c953b27e56fef1424 357 Pfam PF00534 Glycosyl transferases group 1 182 336 1.8E-36 T 01-11-2018 IPR001296 Glycosyl transferase, family 1 AFULGI_00009070 4b54e0147681632137a69129cfe75148 377 PIRSF PIRSF000484 48 372 2.4E-49 T 01-11-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 AFULGI_00009070 4b54e0147681632137a69129cfe75148 377 PIRSF PIRSF000484 1 61 7.6 T 01-11-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 AFULGI_00009070 4b54e0147681632137a69129cfe75148 377 Gene3D G3DSA:3.90.1170.20 1 95 2.5E-34 T 01-11-2018 IPR037128 Quinolinate phosphoribosyl transferase, N-terminal domain superfamily GO:0016763 Reactome: R-HSA-196807 AFULGI_00009070 4b54e0147681632137a69129cfe75148 377 Gene3D G3DSA:3.20.20.70 96 285 2.8E-62 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFULGI_00009070 4b54e0147681632137a69129cfe75148 377 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 104 291 1.3E-47 T 01-11-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 Reactome: R-HSA-196807 AFULGI_00009070 4b54e0147681632137a69129cfe75148 377 SUPERFAMILY SSF51690 100 366 1.26E-71 T 01-11-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 AFULGI_00009070 4b54e0147681632137a69129cfe75148 377 SUPERFAMILY SSF54675 2 104 1.83E-31 T 01-11-2018 AFULGI_00009070 4b54e0147681632137a69129cfe75148 377 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 33 102 1.0E-5 T 01-11-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 AFULGI_00004640 16aa586e41a7b70a17c8e2e94b3a10cf 446 SUPERFAMILY SSF53738 8 177 1.33E-39 T 01-11-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFULGI_00004640 16aa586e41a7b70a17c8e2e94b3a10cf 446 SUPERFAMILY SSF53738 256 362 1.37E-27 T 01-11-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFULGI_00004640 16aa586e41a7b70a17c8e2e94b3a10cf 446 SUPERFAMILY SSF53738 155 255 9.03E-31 T 01-11-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFULGI_00004640 16aa586e41a7b70a17c8e2e94b3a10cf 446 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 257 364 8.8E-25 T 01-11-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFULGI_00004640 16aa586e41a7b70a17c8e2e94b3a10cf 446 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 156 252 3.8E-26 T 01-11-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFULGI_00004640 16aa586e41a7b70a17c8e2e94b3a10cf 446 SUPERFAMILY SSF55957 355 446 2.09E-22 T 01-11-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFULGI_00004640 16aa586e41a7b70a17c8e2e94b3a10cf 446 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 204 217 9.8E-20 T 01-11-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFULGI_00004640 16aa586e41a7b70a17c8e2e94b3a10cf 446 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 232 247 9.8E-20 T 01-11-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFULGI_00004640 16aa586e41a7b70a17c8e2e94b3a10cf 446 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 93 107 9.8E-20 T 01-11-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFULGI_00004640 16aa586e41a7b70a17c8e2e94b3a10cf 446 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 170 189 9.8E-20 T 01-11-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFULGI_00004640 16aa586e41a7b70a17c8e2e94b3a10cf 446 Gene3D G3DSA:3.40.120.10 169 354 8.0E-69 T 01-11-2018 AFULGI_00004640 16aa586e41a7b70a17c8e2e94b3a10cf 446 Gene3D G3DSA:3.40.120.10 7 151 5.5E-46 T 01-11-2018 AFULGI_00004640 16aa586e41a7b70a17c8e2e94b3a10cf 446 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 373 433 1.8E-14 T 01-11-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFULGI_00004640 16aa586e41a7b70a17c8e2e94b3a10cf 446 Gene3D G3DSA:3.40.120.10 253 359 8.0E-69 T 01-11-2018 AFULGI_00004640 16aa586e41a7b70a17c8e2e94b3a10cf 446 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 8 131 2.3E-38 T 01-11-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFULGI_00004640 16aa586e41a7b70a17c8e2e94b3a10cf 446 Gene3D G3DSA:3.30.310.50 367 446 2.7E-22 T 01-11-2018 AFULGI_00004640 16aa586e41a7b70a17c8e2e94b3a10cf 446 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 94 103 - T 01-11-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFULGI_00004640 16aa586e41a7b70a17c8e2e94b3a10cf 446 TIGRFAM TIGR03990 Arch_GlmM: phosphoglucosamine mutase 8 438 3.9E-176 T 01-11-2018 IPR024086 Phosphoglucosamine mutase, archaeal type GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFULGI_00003740 994beaf2c46c4d3dfb155792eac1ecc6 264 Pfam PF13344 Haloacid dehalogenase-like hydrolase 8 107 9.4E-22 T 01-11-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA AFULGI_00003740 994beaf2c46c4d3dfb155792eac1ecc6 264 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 8 230 1.7E-40 T 01-11-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA AFULGI_00003740 994beaf2c46c4d3dfb155792eac1ecc6 264 Gene3D G3DSA:3.40.50.1000 84 181 2.1E-94 T 01-11-2018 IPR023214 HAD superfamily AFULGI_00003740 994beaf2c46c4d3dfb155792eac1ecc6 264 Gene3D G3DSA:3.40.50.1000 7 255 2.1E-94 T 01-11-2018 IPR023214 HAD superfamily AFULGI_00003740 994beaf2c46c4d3dfb155792eac1ecc6 264 PIRSF PIRSF000915 5 264 2.4E-54 T 01-11-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA AFULGI_00003740 994beaf2c46c4d3dfb155792eac1ecc6 264 Pfam PF13242 HAD-hyrolase-like 181 257 7.2E-18 T 01-11-2018 AFULGI_00003740 994beaf2c46c4d3dfb155792eac1ecc6 264 SUPERFAMILY SSF56784 4 259 1.09E-62 T 01-11-2018 IPR036412 HAD-like superfamily AFULGI_00007450 b4824608a965290947ac654f05710111 195 Gene3D G3DSA:1.10.510.10 76 190 2.5E-23 T 01-11-2018 AFULGI_00007450 b4824608a965290947ac654f05710111 195 Pfam PF01163 RIO1 family 10 126 1.5E-10 T 01-11-2018 AFULGI_00007450 b4824608a965290947ac654f05710111 195 SUPERFAMILY SSF56112 15 176 5.26E-23 T 01-11-2018 IPR011009 Protein kinase-like domain superfamily AFULGI_00007450 b4824608a965290947ac654f05710111 195 ProSitePatterns PS00109 Tyrosine protein kinases specific active-site signature. 103 115 - T 01-11-2018 IPR008266 Tyrosine-protein kinase, active site GO:0004672|GO:0006468 AFULGI_00007450 b4824608a965290947ac654f05710111 195 Gene3D G3DSA:3.30.200.20 9 74 6.8E-19 T 01-11-2018 AFULGI_00007450 b4824608a965290947ac654f05710111 195 TIGRFAM TIGR03724 arch_bud32: Kae1-associated kinase Bud32 5 189 2.8E-66 T 01-11-2018 IPR022495 Serine/threonine-protein kinase Bud32 GO:0004674 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6782315|Reactome: R-HSA-6804756 AFULGI_00019920 1b30512b523fdd74e12944de4c7beba1 176 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 8 169 5.7E-62 T 01-11-2018 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AFULGI_00019920 1b30512b523fdd74e12944de4c7beba1 176 Gene3D G3DSA:3.40.50.2020 2 170 3.9E-50 T 01-11-2018 AFULGI_00019920 1b30512b523fdd74e12944de4c7beba1 176 Pfam PF00156 Phosphoribosyl transferase domain 50 153 1.7E-15 T 01-11-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 AFULGI_00019920 1b30512b523fdd74e12944de4c7beba1 176 SUPERFAMILY SSF53271 4 164 2.49E-40 T 01-11-2018 IPR029057 Phosphoribosyltransferase-like AFULGI_00019920 1b30512b523fdd74e12944de4c7beba1 176 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 176 24.528 T 01-11-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AFULGI_00007340 d080dd21be7ed68f333bfdc74947364d 466 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 155 231 1.5E-7 T 01-11-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFULGI_00007340 d080dd21be7ed68f333bfdc74947364d 466 PIRSF PIRSF038984 1 79 1.8E-11 T 01-11-2018 IPR028348 FAD dependent protein AFULGI_00007340 d080dd21be7ed68f333bfdc74947364d 466 PIRSF PIRSF038984 121 465 3.5E-27 T 01-11-2018 IPR028348 FAD dependent protein AFULGI_00007340 d080dd21be7ed68f333bfdc74947364d 466 Gene3D G3DSA:3.50.50.100 140 237 1.1E-10 T 01-11-2018 AFULGI_00007340 d080dd21be7ed68f333bfdc74947364d 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 417 439 3.1E-10 T 01-11-2018 AFULGI_00007340 d080dd21be7ed68f333bfdc74947364d 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 3.1E-10 T 01-11-2018 AFULGI_00007340 d080dd21be7ed68f333bfdc74947364d 466 Gene3D G3DSA:3.50.50.60 1 84 2.0E-18 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFULGI_00007340 d080dd21be7ed68f333bfdc74947364d 466 Gene3D G3DSA:3.50.50.60 404 461 5.0E-6 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFULGI_00007340 d080dd21be7ed68f333bfdc74947364d 466 SUPERFAMILY SSF51905 1 461 3.46E-29 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFULGI_00002660 c714804d13ab1a4a9bc480ed1105b976 534 Gene3D G3DSA:3.10.20.440 12 108 9.0E-32 T 01-11-2018 AFULGI_00002660 c714804d13ab1a4a9bc480ed1105b976 534 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 281 290 2.3E-19 T 01-11-2018 AFULGI_00002660 c714804d13ab1a4a9bc480ed1105b976 534 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 459 466 2.3E-19 T 01-11-2018 AFULGI_00002660 c714804d13ab1a4a9bc480ed1105b976 534 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 322 347 2.3E-19 T 01-11-2018 AFULGI_00002660 c714804d13ab1a4a9bc480ed1105b976 534 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 413 427 2.3E-19 T 01-11-2018 AFULGI_00002660 c714804d13ab1a4a9bc480ed1105b976 534 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 171 193 2.3E-19 T 01-11-2018 AFULGI_00002660 c714804d13ab1a4a9bc480ed1105b976 534 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 172 191 7.2E-20 T 01-11-2018 AFULGI_00002660 c714804d13ab1a4a9bc480ed1105b976 534 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 278 296 7.2E-20 T 01-11-2018 AFULGI_00002660 c714804d13ab1a4a9bc480ed1105b976 534 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 322 340 7.2E-20 T 01-11-2018 AFULGI_00002660 c714804d13ab1a4a9bc480ed1105b976 534 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 412 428 7.2E-20 T 01-11-2018 AFULGI_00002660 c714804d13ab1a4a9bc480ed1105b976 534 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 444 466 7.2E-20 T 01-11-2018 AFULGI_00002660 c714804d13ab1a4a9bc480ed1105b976 534 SUPERFAMILY SSF51905 170 489 8.85E-37 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFULGI_00002660 c714804d13ab1a4a9bc480ed1105b976 534 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 21 101 1.1E-31 T 01-11-2018 AFULGI_00002660 c714804d13ab1a4a9bc480ed1105b976 534 SUPERFAMILY SSF54292 23 106 1.14E-24 T 01-11-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 AFULGI_00002660 c714804d13ab1a4a9bc480ed1105b976 534 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 66 74 - T 01-11-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 AFULGI_00002660 c714804d13ab1a4a9bc480ed1105b976 534 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 171 478 1.6E-46 T 01-11-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFULGI_00002660 c714804d13ab1a4a9bc480ed1105b976 534 Gene3D G3DSA:3.50.50.60 164 315 2.2E-32 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFULGI_00002660 c714804d13ab1a4a9bc480ed1105b976 534 Gene3D G3DSA:3.50.50.60 323 518 4.2E-19 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFULGI_00014930 e86af99827a1de4600e0b458274e507e 351 Gene3D G3DSA:4.10.480.10 226 334 1.5E-27 T 01-11-2018 IPR037148 [NiFe]-hydrogenase, small subunit, C-terminal domain superfamily AFULGI_00014930 e86af99827a1de4600e0b458274e507e 351 SUPERFAMILY SSF56770 39 304 4.55E-66 T 01-11-2018 AFULGI_00014930 e86af99827a1de4600e0b458274e507e 351 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 49 204 6.0E-30 T 01-11-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFULGI_00014930 e86af99827a1de4600e0b458274e507e 351 Pfam PF14720 NiFe/NiFeSe hydrogenase small subunit C-terminal 223 303 1.1E-28 T 01-11-2018 IPR027394 Cytochrome-c3 hydrogenase, C-terminal AFULGI_00014930 e86af99827a1de4600e0b458274e507e 351 TIGRFAM TIGR00391 hydA: hydrogenase (NiFe) small subunit (hydA) 3 342 1.9E-67 T 01-11-2018 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 AFULGI_00014930 e86af99827a1de4600e0b458274e507e 351 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 3 31 3.0E-5 T 01-11-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal AFULGI_00014930 e86af99827a1de4600e0b458274e507e 351 Gene3D G3DSA:3.40.50.700 26 222 4.3E-55 T 01-11-2018 IPR037024 [NiFe]-hydrogenase, small subunit, N-terminal domain superfamily AFULGI_00014930 e86af99827a1de4600e0b458274e507e 351 PIRSF PIRSF000310 1 350 5.7E-118 T 01-11-2018 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 AFULGI_00018030 ae1fb9b5907afa9b62760fea7136e10a 95 SUPERFAMILY SSF160363 3 92 1.06E-34 T 01-11-2018 IPR023129 MTH889-like domain superfamily AFULGI_00018030 ae1fb9b5907afa9b62760fea7136e10a 95 Gene3D G3DSA:3.30.70.1340 1 86 4.4E-37 T 01-11-2018 IPR023129 MTH889-like domain superfamily AFULGI_00018030 ae1fb9b5907afa9b62760fea7136e10a 95 ProDom PD012512 ARCHAEA PH1931 STS176 TA1183 MJ0319 PRECURSOR TVG0378908 UNCHARACTERIZED DUF211 AF1549 11 94 2.0E-40 T 01-11-2018 IPR003831 Protein of unknown function DUF211 AFULGI_00018030 ae1fb9b5907afa9b62760fea7136e10a 95 Pfam PF02680 Uncharacterized ArCR, COG1888 4 90 1.8E-38 T 01-11-2018 IPR003831 Protein of unknown function DUF211 AFULGI_00008200 c04a9dce84e86119e7d3283d3af30ecb 149 Pfam PF00583 Acetyltransferase (GNAT) family 16 123 3.2E-19 T 01-11-2018 IPR000182 GNAT domain AFULGI_00008200 c04a9dce84e86119e7d3283d3af30ecb 149 SUPERFAMILY SSF55729 4 144 6.55E-32 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase AFULGI_00008200 c04a9dce84e86119e7d3283d3af30ecb 149 Gene3D G3DSA:3.40.630.30 1 148 5.4E-37 T 01-11-2018 AFULGI_00008200 c04a9dce84e86119e7d3283d3af30ecb 149 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 13 142 8.2E-42 T 01-11-2018 IPR006464 N-acetyltransferase RimI/Ard1 GO:0006474|GO:0016407 AFULGI_00000210 5563a831687a393475d9e6b3dff73006 591 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 222 587 9.0E-106 T 01-11-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 AFULGI_00000210 5563a831687a393475d9e6b3dff73006 591 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 5 202 1.2E-74 T 01-11-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 AFULGI_00000210 5563a831687a393475d9e6b3dff73006 591 Gene3D G3DSA:1.10.569.10 239 411 1.6E-107 T 01-11-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 AFULGI_00000210 5563a831687a393475d9e6b3dff73006 591 SMART SM00790 3 204 4.2E-116 T 01-11-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 AFULGI_00000210 5563a831687a393475d9e6b3dff73006 591 Gene3D G3DSA:1.10.599.10 237 587 1.6E-107 T 01-11-2018 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 AFULGI_00000210 5563a831687a393475d9e6b3dff73006 591 SUPERFAMILY SSF56228 2 204 2.62E-72 T 01-11-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily AFULGI_00000210 5563a831687a393475d9e6b3dff73006 591 Gene3D G3DSA:3.60.9.10 1 207 6.1E-81 T 01-11-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily AFULGI_00000210 5563a831687a393475d9e6b3dff73006 591 SUPERFAMILY SSF48310 211 590 4.45E-110 T 01-11-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 AFULGI_00000580 86a909438869e481b231d8a15e32ebda 137 SUPERFAMILY SSF88723 1 130 7.85E-24 T 01-11-2018 IPR029060 PIN-like domain superfamily AFULGI_00000580 86a909438869e481b231d8a15e32ebda 137 Gene3D G3DSA:3.40.50.1010 2 132 2.8E-17 T 01-11-2018 AFULGI_00000580 86a909438869e481b231d8a15e32ebda 137 Pfam PF01850 PIN domain 3 126 2.2E-22 T 01-11-2018 IPR002716 PIN domain AFULGI_00000580 86a909438869e481b231d8a15e32ebda 137 SMART SM00670 1 123 7.9E-20 T 01-11-2018 IPR002716 PIN domain AFULGI_00005390 1e7948a9b43b0574b738ea5c4e9e6c2f 628 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 559 616 1.7E-29 T 01-11-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 AFULGI_00005390 1e7948a9b43b0574b738ea5c4e9e6c2f 628 Gene3D G3DSA:3.40.50.670 397 628 1.9E-107 T 01-11-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AFULGI_00005390 1e7948a9b43b0574b738ea5c4e9e6c2f 628 SUPERFAMILY SSF56719 393 621 1.49E-87 T 01-11-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 AFULGI_00005390 1e7948a9b43b0574b738ea5c4e9e6c2f 628 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 7 628 88.126 T 01-11-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 AFULGI_00005390 1e7948a9b43b0574b738ea5c4e9e6c2f 628 Pfam PF00204 DNA gyrase B 223 388 1.4E-53 T 01-11-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AFULGI_00005390 1e7948a9b43b0574b738ea5c4e9e6c2f 628 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 10 628 1.6E-285 T 01-11-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 AFULGI_00005390 1e7948a9b43b0574b738ea5c4e9e6c2f 628 Gene3D G3DSA:3.30.230.10 222 396 3.0E-64 T 01-11-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AFULGI_00005390 1e7948a9b43b0574b738ea5c4e9e6c2f 628 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 38 177 1.1E-22 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFULGI_00005390 1e7948a9b43b0574b738ea5c4e9e6c2f 628 SMART SM00387 35 178 3.7E-26 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFULGI_00005390 1e7948a9b43b0574b738ea5c4e9e6c2f 628 SUPERFAMILY SSF54211 223 389 1.25E-49 T 01-11-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFULGI_00005390 1e7948a9b43b0574b738ea5c4e9e6c2f 628 PRINTS PR01159 DNA gyrase subunit B signature 310 326 3.2E-62 T 01-11-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AFULGI_00005390 1e7948a9b43b0574b738ea5c4e9e6c2f 628 PRINTS PR01159 DNA gyrase subunit B signature 10 20 3.2E-62 T 01-11-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AFULGI_00005390 1e7948a9b43b0574b738ea5c4e9e6c2f 628 PRINTS PR01159 DNA gyrase subunit B signature 597 613 3.2E-62 T 01-11-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AFULGI_00005390 1e7948a9b43b0574b738ea5c4e9e6c2f 628 PRINTS PR01159 DNA gyrase subunit B signature 372 392 3.2E-62 T 01-11-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AFULGI_00005390 1e7948a9b43b0574b738ea5c4e9e6c2f 628 PRINTS PR01159 DNA gyrase subunit B signature 183 198 3.2E-62 T 01-11-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AFULGI_00005390 1e7948a9b43b0574b738ea5c4e9e6c2f 628 PRINTS PR01159 DNA gyrase subunit B signature 467 476 3.2E-62 T 01-11-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AFULGI_00005390 1e7948a9b43b0574b738ea5c4e9e6c2f 628 PRINTS PR01159 DNA gyrase subunit B signature 358 372 3.2E-62 T 01-11-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AFULGI_00005390 1e7948a9b43b0574b738ea5c4e9e6c2f 628 PRINTS PR01159 DNA gyrase subunit B signature 198 211 3.2E-62 T 01-11-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AFULGI_00005390 1e7948a9b43b0574b738ea5c4e9e6c2f 628 PRINTS PR01159 DNA gyrase subunit B signature 243 261 3.2E-62 T 01-11-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AFULGI_00005390 1e7948a9b43b0574b738ea5c4e9e6c2f 628 PRINTS PR01159 DNA gyrase subunit B signature 581 593 3.2E-62 T 01-11-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AFULGI_00005390 1e7948a9b43b0574b738ea5c4e9e6c2f 628 SUPERFAMILY SSF55874 9 220 2.6E-72 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFULGI_00005390 1e7948a9b43b0574b738ea5c4e9e6c2f 628 PRINTS PR00418 DNA topoisomerase II family signature 521 533 2.6E-71 T 01-11-2018 AFULGI_00005390 1e7948a9b43b0574b738ea5c4e9e6c2f 628 PRINTS PR00418 DNA topoisomerase II family signature 417 431 2.6E-71 T 01-11-2018 AFULGI_00005390 1e7948a9b43b0574b738ea5c4e9e6c2f 628 PRINTS PR00418 DNA topoisomerase II family signature 560 576 2.6E-71 T 01-11-2018 AFULGI_00005390 1e7948a9b43b0574b738ea5c4e9e6c2f 628 PRINTS PR00418 DNA topoisomerase II family signature 501 518 2.6E-71 T 01-11-2018 AFULGI_00005390 1e7948a9b43b0574b738ea5c4e9e6c2f 628 PRINTS PR00418 DNA topoisomerase II family signature 269 282 2.6E-71 T 01-11-2018 AFULGI_00005390 1e7948a9b43b0574b738ea5c4e9e6c2f 628 PRINTS PR00418 DNA topoisomerase II family signature 39 54 2.6E-71 T 01-11-2018 AFULGI_00005390 1e7948a9b43b0574b738ea5c4e9e6c2f 628 PRINTS PR00418 DNA topoisomerase II family signature 483 499 2.6E-71 T 01-11-2018 AFULGI_00005390 1e7948a9b43b0574b738ea5c4e9e6c2f 628 PRINTS PR00418 DNA topoisomerase II family signature 116 130 2.6E-71 T 01-11-2018 AFULGI_00005390 1e7948a9b43b0574b738ea5c4e9e6c2f 628 PRINTS PR00418 DNA topoisomerase II family signature 74 87 2.6E-71 T 01-11-2018 AFULGI_00005390 1e7948a9b43b0574b738ea5c4e9e6c2f 628 SMART SM00433 39 621 0.0 T 01-11-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AFULGI_00005390 1e7948a9b43b0574b738ea5c4e9e6c2f 628 Pfam PF01751 Toprim domain 416 526 8.5E-18 T 01-11-2018 IPR006171 TOPRIM domain AFULGI_00005390 1e7948a9b43b0574b738ea5c4e9e6c2f 628 Gene3D G3DSA:3.30.565.10 7 221 1.7E-93 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFULGI_00002510 7541f6790b2f6175f580395a4015951a 546 SUPERFAMILY SSF50715 398 536 1.62E-17 T 01-11-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 AFULGI_00002510 7541f6790b2f6175f580395a4015951a 546 Gene3D G3DSA:2.40.240.100 400 545 1.4E-34 T 01-11-2018 AFULGI_00002510 7541f6790b2f6175f580395a4015951a 546 PRINTS PR00987 Glutamyl-tRNA synthetase signature 121 134 1.9E-14 T 01-11-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 AFULGI_00002510 7541f6790b2f6175f580395a4015951a 546 PRINTS PR00987 Glutamyl-tRNA synthetase signature 284 292 1.9E-14 T 01-11-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 AFULGI_00002510 7541f6790b2f6175f580395a4015951a 546 PRINTS PR00987 Glutamyl-tRNA synthetase signature 92 104 1.9E-14 T 01-11-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 AFULGI_00002510 7541f6790b2f6175f580395a4015951a 546 PRINTS PR00987 Glutamyl-tRNA synthetase signature 106 117 1.9E-14 T 01-11-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 AFULGI_00002510 7541f6790b2f6175f580395a4015951a 546 PRINTS PR00987 Glutamyl-tRNA synthetase signature 268 278 1.9E-14 T 01-11-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 AFULGI_00002510 7541f6790b2f6175f580395a4015951a 546 TIGRFAM TIGR00463 gltX_arch: glutamate--tRNA ligase 1 546 5.8E-264 T 01-11-2018 IPR004526 Glutamyl-tRNA synthetase, archaeal/eukaryotic cytosolic GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 AFULGI_00002510 7541f6790b2f6175f580395a4015951a 546 Gene3D G3DSA:2.40.240.10 407 494 1.4E-34 T 01-11-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 AFULGI_00002510 7541f6790b2f6175f580395a4015951a 546 Pfam PF03950 tRNA synthetases class I (E and Q), anti-codon binding domain 398 532 1.6E-21 T 01-11-2018 IPR020059 Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 AFULGI_00002510 7541f6790b2f6175f580395a4015951a 546 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 88 394 5.4E-73 T 01-11-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 AFULGI_00002510 7541f6790b2f6175f580395a4015951a 546 Hamap MF_02076 Glutamate--tRNA ligase [gltX]. 1 544 35.942 T 01-11-2018 IPR004526 Glutamyl-tRNA synthetase, archaeal/eukaryotic cytosolic GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 AFULGI_00002510 7541f6790b2f6175f580395a4015951a 546 Gene3D G3DSA:3.40.50.620 52 399 3.7E-107 T 01-11-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFULGI_00002510 7541f6790b2f6175f580395a4015951a 546 SUPERFAMILY SSF52374 88 403 9.12E-84 T 01-11-2018 AFULGI_00026280 ff9954c87ab9dd0dcabf72a81912b2fb 93 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 1 93 25.12 T 01-11-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 AFULGI_00026280 ff9954c87ab9dd0dcabf72a81912b2fb 93 SUPERFAMILY SSF141000 1 91 1.96E-26 T 01-11-2018 IPR036113 Glu-tRNAGln amidotransferase superfamily, subunit C GO:0006450 AFULGI_00026280 ff9954c87ab9dd0dcabf72a81912b2fb 93 Gene3D G3DSA:1.10.20.60 1 91 1.8E-25 T 01-11-2018 AFULGI_00026280 ff9954c87ab9dd0dcabf72a81912b2fb 93 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 2 93 1.3E-32 T 01-11-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 AFULGI_00026280 ff9954c87ab9dd0dcabf72a81912b2fb 93 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 18 87 6.1E-21 T 01-11-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 AFULGI_00020370 abd7eeeb410f0f47842dcaadc4a91600 170 Pfam PF01613 Flavin reductase like domain 11 144 2.6E-25 T 01-11-2018 IPR002563 Flavin reductase like domain GO:0010181 AFULGI_00020370 abd7eeeb410f0f47842dcaadc4a91600 170 SUPERFAMILY SSF50475 6 162 2.26E-39 T 01-11-2018 AFULGI_00020370 abd7eeeb410f0f47842dcaadc4a91600 170 SMART SM00903 5 154 4.0E-22 T 01-11-2018 IPR002563 Flavin reductase like domain GO:0010181 AFULGI_00020370 abd7eeeb410f0f47842dcaadc4a91600 170 Gene3D G3DSA:2.30.110.10 2 166 9.9E-46 T 01-11-2018 IPR012349 FMN-binding split barrel GO:0048037 AFULGI_00007480 063f569c1e243c1de4cf909daebd891d 101 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 13 99 6.3E-25 T 01-11-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis AFULGI_00007480 063f569c1e243c1de4cf909daebd891d 101 Gene3D G3DSA:3.30.420.130 1 101 6.9E-28 T 01-11-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily AFULGI_00007480 063f569c1e243c1de4cf909daebd891d 101 SUPERFAMILY SSF53146 1 99 4.32E-26 T 01-11-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily AFULGI_00010640 95430097d3b8163804818f99c93f7a40 450 SUPERFAMILY SSF89796 34 450 1.31E-91 T 01-11-2018 IPR023606 CoA-transferase family III domain superfamily AFULGI_00010640 95430097d3b8163804818f99c93f7a40 450 Gene3D G3DSA:3.40.50.10540 37 444 9.3E-92 T 01-11-2018 IPR023606 CoA-transferase family III domain superfamily AFULGI_00010640 95430097d3b8163804818f99c93f7a40 450 Pfam PF02515 CoA-transferase family III 36 426 3.5E-118 T 01-11-2018 IPR003673 CoA-transferase family III GO:0003824 AFULGI_00010640 95430097d3b8163804818f99c93f7a40 450 Gene3D G3DSA:3.30.1540.10 277 376 9.3E-92 T 01-11-2018 AFULGI_00013960 f313567cb833bd658e8322ba0e3d0315 584 Pfam PF00501 AMP-binding enzyme 53 462 9.3E-69 T 01-11-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFULGI_00013960 f313567cb833bd658e8322ba0e3d0315 584 SUPERFAMILY SSF56801 28 561 3.27E-128 T 01-11-2018 AFULGI_00013960 f313567cb833bd658e8322ba0e3d0315 584 Gene3D G3DSA:3.30.300.30 458 576 8.0E-28 T 01-11-2018 AFULGI_00013960 f313567cb833bd658e8322ba0e3d0315 584 Gene3D G3DSA:3.40.50.12780 14 456 5.8E-102 T 01-11-2018 AFULGI_00013960 f313567cb833bd658e8322ba0e3d0315 584 Pfam PF13193 AMP-binding enzyme C-terminal domain 471 549 6.8E-23 T 01-11-2018 IPR025110 AMP-binding enzyme, C-terminal domain AFULGI_00018640 fa27fc28a8804c804f4fe79ce19ca997 113 SUPERFAMILY SSF81301 25 110 3.78E-19 T 01-11-2018 AFULGI_00018640 fa27fc28a8804c804f4fe79ce19ca997 113 Pfam PF01909 Nucleotidyltransferase domain 25 101 2.8E-14 T 01-11-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 AFULGI_00018640 fa27fc28a8804c804f4fe79ce19ca997 113 Gene3D G3DSA:3.30.460.10 21 113 7.3E-29 T 01-11-2018 AFULGI_00017410 a04b0c0091bbbc005e19f622ddba7018 623 Pfam PF00037 4Fe-4S binding domain 596 618 1.8E-6 T 01-11-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFULGI_00017410 a04b0c0091bbbc005e19f622ddba7018 623 SUPERFAMILY SSF52518 370 577 9.26E-32 T 01-11-2018 IPR029061 Thiamin diphosphate-binding fold AFULGI_00017410 a04b0c0091bbbc005e19f622ddba7018 623 SUPERFAMILY SSF52922 233 347 7.2E-13 T 01-11-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 AFULGI_00017410 a04b0c0091bbbc005e19f622ddba7018 623 SUPERFAMILY SSF52518 11 248 1.95E-57 T 01-11-2018 IPR029061 Thiamin diphosphate-binding fold AFULGI_00017410 a04b0c0091bbbc005e19f622ddba7018 623 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 25 193 5.6E-15 T 01-11-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 AFULGI_00017410 a04b0c0091bbbc005e19f622ddba7018 623 Gene3D G3DSA:3.40.50.970 383 567 1.0E-18 T 01-11-2018 AFULGI_00017410 a04b0c0091bbbc005e19f622ddba7018 623 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 602 613 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFULGI_00017410 a04b0c0091bbbc005e19f622ddba7018 623 PIRSF PIRSF006439 2 623 7.6E-272 T 01-11-2018 IPR017721 Indolepyruvate ferredoxin oxidoreductase, alpha subunit GO:0043805|GO:0055114 AFULGI_00017410 a04b0c0091bbbc005e19f622ddba7018 623 TIGRFAM TIGR03336 IOR_alpha: indolepyruvate ferredoxin oxidoreductase, alpha subunit 13 617 8.0E-234 T 01-11-2018 IPR017721 Indolepyruvate ferredoxin oxidoreductase, alpha subunit GO:0043805|GO:0055114 AFULGI_00017410 a04b0c0091bbbc005e19f622ddba7018 623 Gene3D G3DSA:3.30.70.20 568 621 4.4E-8 T 01-11-2018 AFULGI_00017410 a04b0c0091bbbc005e19f622ddba7018 623 Gene3D G3DSA:3.40.50.970 2 196 8.9E-55 T 01-11-2018 AFULGI_00017410 a04b0c0091bbbc005e19f622ddba7018 623 SUPERFAMILY SSF54862 558 618 1.04E-10 T 01-11-2018 AFULGI_00017410 a04b0c0091bbbc005e19f622ddba7018 623 Gene3D G3DSA:3.40.50.920 235 333 7.7E-8 T 01-11-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 AFULGI_00017410 a04b0c0091bbbc005e19f622ddba7018 623 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 404 545 5.5E-28 T 01-11-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 AFULGI_00002170 4c88206be59aab8e7f6539b575dae03b 264 SMART SM00079 39 264 8.1E-6 T 01-11-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 AFULGI_00002170 4c88206be59aab8e7f6539b575dae03b 264 Gene3D G3DSA:3.40.190.10 124 227 2.6E-82 T 01-11-2018 AFULGI_00002170 4c88206be59aab8e7f6539b575dae03b 264 SMART SM00062 39 264 3.6E-97 T 01-11-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF AFULGI_00002170 4c88206be59aab8e7f6539b575dae03b 264 SUPERFAMILY SSF53850 1 263 1.82E-82 T 01-11-2018 AFULGI_00002170 4c88206be59aab8e7f6539b575dae03b 264 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 63 76 - T 01-11-2018 IPR018313 Solute-binding protein family 3, conserved site AFULGI_00002170 4c88206be59aab8e7f6539b575dae03b 264 Gene3D G3DSA:3.40.190.10 38 262 2.6E-82 T 01-11-2018 AFULGI_00002170 4c88206be59aab8e7f6539b575dae03b 264 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 40 264 1.1E-78 T 01-11-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF AFULGI_00020860 bee010d2fbd72cfee766d9eed695f7e4 251 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 229 240 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFULGI_00020860 bee010d2fbd72cfee766d9eed695f7e4 251 SUPERFAMILY SSF54862 39 125 6.0E-21 T 01-11-2018 AFULGI_00020860 bee010d2fbd72cfee766d9eed695f7e4 251 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 93 104 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFULGI_00020860 bee010d2fbd72cfee766d9eed695f7e4 251 Pfam PF12838 4Fe-4S dicluster domain 186 242 5.9E-8 T 01-11-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFULGI_00020860 bee010d2fbd72cfee766d9eed695f7e4 251 SUPERFAMILY SSF54862 172 247 4.6E-14 T 01-11-2018 AFULGI_00020860 bee010d2fbd72cfee766d9eed695f7e4 251 PIRSF PIRSF005658 23 87 1.8E-6 T 01-11-2018 AFULGI_00020860 bee010d2fbd72cfee766d9eed695f7e4 251 PIRSF PIRSF005658 162 251 1.3E-9 T 01-11-2018 AFULGI_00020860 bee010d2fbd72cfee766d9eed695f7e4 251 PIRSF PIRSF005658 82 134 2.4E-5 T 01-11-2018 AFULGI_00020860 bee010d2fbd72cfee766d9eed695f7e4 251 Gene3D G3DSA:3.30.70.20 172 209 3.3E-5 T 01-11-2018 AFULGI_00020860 bee010d2fbd72cfee766d9eed695f7e4 251 Gene3D G3DSA:3.30.70.20 210 250 1.3E-6 T 01-11-2018 AFULGI_00020860 bee010d2fbd72cfee766d9eed695f7e4 251 Pfam PF13187 4Fe-4S dicluster domain 60 107 3.5E-9 T 01-11-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFULGI_00020860 bee010d2fbd72cfee766d9eed695f7e4 251 Gene3D G3DSA:3.30.70.3270 39 171 1.1E-20 T 01-11-2018 AFULGI_00019980 475fd1d3bf7a1a6119ad176dc8a4b1dd 112 Gene3D G3DSA:3.30.70.120 1 112 9.1E-48 T 01-11-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal AFULGI_00019980 475fd1d3bf7a1a6119ad176dc8a4b1dd 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 2.7E-37 T 01-11-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AFULGI_00019980 475fd1d3bf7a1a6119ad176dc8a4b1dd 112 PRINTS PR00340 P-II protein signature 2 17 2.4E-36 T 01-11-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AFULGI_00019980 475fd1d3bf7a1a6119ad176dc8a4b1dd 112 PRINTS PR00340 P-II protein signature 83 103 2.4E-36 T 01-11-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AFULGI_00019980 475fd1d3bf7a1a6119ad176dc8a4b1dd 112 PRINTS PR00340 P-II protein signature 23 41 2.4E-36 T 01-11-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AFULGI_00019980 475fd1d3bf7a1a6119ad176dc8a4b1dd 112 PRINTS PR00340 P-II protein signature 52 75 2.4E-36 T 01-11-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AFULGI_00019980 475fd1d3bf7a1a6119ad176dc8a4b1dd 112 SMART SM00938 4 105 1.5E-53 T 01-11-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AFULGI_00019980 475fd1d3bf7a1a6119ad176dc8a4b1dd 112 SUPERFAMILY SSF54913 1 112 4.13E-41 T 01-11-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta AFULGI_00019980 475fd1d3bf7a1a6119ad176dc8a4b1dd 112 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 01-11-2018 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 AFULGI_00015470 d0b9f393f2d74ba2d1c1d32a1a4928d7 181 Gene3D G3DSA:3.30.2170.10 1 181 6.8E-76 T 01-11-2018 AFULGI_00015470 d0b9f393f2d74ba2d1c1d32a1a4928d7 181 Hamap MF_00582 UPF0215 protein . 4 174 32.592 T 01-11-2018 IPR002802 Protein of unknown function DUF99 AFULGI_00015470 d0b9f393f2d74ba2d1c1d32a1a4928d7 181 PIRSF PIRSF006380 1 181 3.1E-66 T 01-11-2018 IPR002802 Protein of unknown function DUF99 AFULGI_00015470 d0b9f393f2d74ba2d1c1d32a1a4928d7 181 Pfam PF01949 Protein of unknown function DUF99 3 172 5.8E-58 T 01-11-2018 IPR002802 Protein of unknown function DUF99 AFULGI_00015470 d0b9f393f2d74ba2d1c1d32a1a4928d7 181 ProDom PD016744 UPF0215 ST0304 TK2033 MA4269 PAE0952 SSO0256 NEQ431 MK0057 PTO0905 TV0037 52 176 9.0E-68 T 01-11-2018 IPR002802 Protein of unknown function DUF99 AFULGI_00023680 78588caddb1cbb6cd8a149a2986a3368 575 Gene3D G3DSA:3.40.50.1220 198 366 7.0E-48 T 01-11-2018 AFULGI_00023680 78588caddb1cbb6cd8a149a2986a3368 575 Gene3D G3DSA:3.40.50.970 367 564 1.2E-60 T 01-11-2018 AFULGI_00023680 78588caddb1cbb6cd8a149a2986a3368 575 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 399 546 1.3E-39 T 01-11-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 AFULGI_00023680 78588caddb1cbb6cd8a149a2986a3368 575 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 436 455 - T 01-11-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 AFULGI_00023680 78588caddb1cbb6cd8a149a2986a3368 575 Gene3D G3DSA:3.40.50.970 1 184 3.7E-63 T 01-11-2018 AFULGI_00023680 78588caddb1cbb6cd8a149a2986a3368 575 SUPERFAMILY SSF52518 1 177 1.09E-51 T 01-11-2018 IPR029061 Thiamin diphosphate-binding fold AFULGI_00023680 78588caddb1cbb6cd8a149a2986a3368 575 SUPERFAMILY SSF52518 373 556 1.07E-57 T 01-11-2018 IPR029061 Thiamin diphosphate-binding fold AFULGI_00023680 78588caddb1cbb6cd8a149a2986a3368 575 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 5 172 8.5E-54 T 01-11-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 AFULGI_00023680 78588caddb1cbb6cd8a149a2986a3368 575 SUPERFAMILY SSF52467 194 383 1.26E-45 T 01-11-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily AFULGI_00023680 78588caddb1cbb6cd8a149a2986a3368 575 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 201 335 2.8E-35 T 01-11-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 AFULGI_00022010 0e9dbc0a4144670e8922169aa1ff79a5 80 SUPERFAMILY SSF82697 3 76 2.44E-24 T 01-11-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 AFULGI_00022010 0e9dbc0a4144670e8922169aa1ff79a5 80 Hamap MF_01926 Phosphoribosylformylglycinamidine synthase subunit PurS [purS]. 1 78 20.177 T 01-11-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 AFULGI_00022010 0e9dbc0a4144670e8922169aa1ff79a5 80 Gene3D G3DSA:3.30.1280.10 1 80 9.1E-29 T 01-11-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 AFULGI_00022010 0e9dbc0a4144670e8922169aa1ff79a5 80 Pfam PF02700 Phosphoribosylformylglycinamidine (FGAM) synthase 3 77 4.2E-29 T 01-11-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 AFULGI_00022010 0e9dbc0a4144670e8922169aa1ff79a5 80 ProDom PD010362 PHOSPHORIBOSYLFORMYLGLYCINAMIDINE PURS SYNTHETASE SYNTHASE COMPONENT SYNTHASE LIGASE FGAM UPF0062 I 9 76 8.0E-20 T 01-11-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 AFULGI_00022010 0e9dbc0a4144670e8922169aa1ff79a5 80 TIGRFAM TIGR00302 TIGR00302: phosphoribosylformylglycinamidine synthase, purS protein 1 80 1.3E-37 T 01-11-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 AFULGI_00007210 2de1184c809e5f680b0b42bd1790af1e 335 SUPERFAMILY SSF53850 208 331 2.04E-20 T 01-11-2018 AFULGI_00007210 2de1184c809e5f680b0b42bd1790af1e 335 SUPERFAMILY SSF53850 25 166 1.71E-16 T 01-11-2018 AFULGI_00007210 2de1184c809e5f680b0b42bd1790af1e 335 Pfam PF13379 NMT1-like family 207 333 2.4E-9 T 01-11-2018 AFULGI_00007210 2de1184c809e5f680b0b42bd1790af1e 335 Pfam PF13379 NMT1-like family 23 118 9.8E-22 T 01-11-2018 AFULGI_00007210 2de1184c809e5f680b0b42bd1790af1e 335 Gene3D G3DSA:3.40.190.10 301 335 4.8E-5 T 01-11-2018 AFULGI_00007210 2de1184c809e5f680b0b42bd1790af1e 335 Gene3D G3DSA:3.40.190.10 8 197 2.1E-31 T 01-11-2018 AFULGI_00007210 2de1184c809e5f680b0b42bd1790af1e 335 Gene3D G3DSA:3.40.190.10 203 300 4.1E-10 T 01-11-2018 AFULGI_00023280 9ca5b19c909e221d64578afcd06320ba 319 Pfam PF08542 Replication factor C C-terminal domain 227 311 2.1E-25 T 01-11-2018 IPR013748 Replication factor C, C-terminal Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-176187|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804756|Reactome: R-HSA-69091|Reactome: R-HSA-69473 AFULGI_00023280 9ca5b19c909e221d64578afcd06320ba 319 Gene3D G3DSA:1.20.272.10 227 319 1.2E-37 T 01-11-2018 AFULGI_00023280 9ca5b19c909e221d64578afcd06320ba 319 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 41 158 3.4E-18 T 01-11-2018 IPR003959 ATPase, AAA-type, core GO:0005524 AFULGI_00023280 9ca5b19c909e221d64578afcd06320ba 319 Gene3D G3DSA:3.40.50.300 1 160 1.3E-60 T 01-11-2018 AFULGI_00023280 9ca5b19c909e221d64578afcd06320ba 319 Gene3D G3DSA:1.10.8.60 161 226 1.2E-29 T 01-11-2018 AFULGI_00023280 9ca5b19c909e221d64578afcd06320ba 319 Hamap MF_01509 Replication factor C small subunit [rfcS]. 3 317 52.829 T 01-11-2018 IPR023748 Replication factor C small subunit, archaeal GO:0003689|GO:0005524|GO:0005663|GO:0006260 AFULGI_00023280 9ca5b19c909e221d64578afcd06320ba 319 SUPERFAMILY SSF48019 227 316 3.7E-25 T 01-11-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 AFULGI_00023280 9ca5b19c909e221d64578afcd06320ba 319 SMART SM00382 37 162 5.5E-12 T 01-11-2018 IPR003593 AAA+ ATPase domain AFULGI_00023280 9ca5b19c909e221d64578afcd06320ba 319 SUPERFAMILY SSF52540 6 221 1.2E-59 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00026080 2df3704c9db1cb4fb225b1ec431c5316 397 PRINTS PR00758 Arsenical pump membrane protein signature 99 123 7.7E-6 T 01-11-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 AFULGI_00026080 2df3704c9db1cb4fb225b1ec431c5316 397 PRINTS PR00758 Arsenical pump membrane protein signature 172 195 7.7E-6 T 01-11-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 AFULGI_00026080 2df3704c9db1cb4fb225b1ec431c5316 397 Pfam PF03600 Citrate transporter 22 344 2.3E-39 T 01-11-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 AFULGI_00000040 b7572390e23e8f289262464fa0f91a26 210 SMART SM01018 2 84 7.2E-24 T 01-11-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFULGI_00000040 b7572390e23e8f289262464fa0f91a26 210 SUPERFAMILY SSF52242 70 208 4.71E-41 T 01-11-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 AFULGI_00000040 b7572390e23e8f289262464fa0f91a26 210 Gene3D G3DSA:3.40.50.280 79 209 2.6E-44 T 01-11-2018 AFULGI_00000040 b7572390e23e8f289262464fa0f91a26 210 Pfam PF02607 B12 binding domain 5 76 8.3E-13 T 01-11-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFULGI_00000040 b7572390e23e8f289262464fa0f91a26 210 SUPERFAMILY SSF47644 4 83 1.14E-16 T 01-11-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFULGI_00000040 b7572390e23e8f289262464fa0f91a26 210 Pfam PF02310 B12 binding domain 90 196 2.7E-26 T 01-11-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 AFULGI_00000040 b7572390e23e8f289262464fa0f91a26 210 Gene3D G3DSA:1.10.1240.10 3 78 5.5E-24 T 01-11-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFULGI_00009120 cbb0ba7190c245b36aed83d35ce0143c 131 Gene3D G3DSA:3.40.50.620 1 131 5.4E-35 T 01-11-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFULGI_00009120 cbb0ba7190c245b36aed83d35ce0143c 131 SUPERFAMILY SSF52402 1 131 1.26E-21 T 01-11-2018 AFULGI_00009120 cbb0ba7190c245b36aed83d35ce0143c 131 Pfam PF00582 Universal stress protein family 2 131 1.3E-23 T 01-11-2018 IPR006016 UspA AFULGI_00006960 5a803e376fd6c0a8f3d6be35607c5f51 358 Gene3D G3DSA:3.40.50.2000 189 343 4.5E-31 T 01-11-2018 AFULGI_00006960 5a803e376fd6c0a8f3d6be35607c5f51 358 Gene3D G3DSA:3.40.50.2000 1 188 2.1E-37 T 01-11-2018 AFULGI_00006960 5a803e376fd6c0a8f3d6be35607c5f51 358 SUPERFAMILY SSF53756 3 355 1.75E-72 T 01-11-2018 AFULGI_00006960 5a803e376fd6c0a8f3d6be35607c5f51 358 Pfam PF00534 Glycosyl transferases group 1 184 330 6.6E-29 T 01-11-2018 IPR001296 Glycosyl transferase, family 1 AFULGI_00006960 5a803e376fd6c0a8f3d6be35607c5f51 358 Pfam PF13439 Glycosyltransferase Family 4 14 179 1.4E-33 T 01-11-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 AFULGI_00000870 21720a5d2a60528c4f29e7e936f4ba07 542 Pfam PF13193 AMP-binding enzyme C-terminal domain 451 528 3.8E-22 T 01-11-2018 IPR025110 AMP-binding enzyme, C-terminal domain AFULGI_00000870 21720a5d2a60528c4f29e7e936f4ba07 542 Gene3D G3DSA:3.40.50.12780 1 435 1.6E-176 T 01-11-2018 AFULGI_00000870 21720a5d2a60528c4f29e7e936f4ba07 542 Gene3D G3DSA:3.30.300.310 438 541 2.5E-30 T 01-11-2018 AFULGI_00000870 21720a5d2a60528c4f29e7e936f4ba07 542 Pfam PF00501 AMP-binding enzyme 25 442 6.3E-92 T 01-11-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFULGI_00000870 21720a5d2a60528c4f29e7e936f4ba07 542 ProSitePatterns PS00455 Putative AMP-binding domain signature. 183 194 - T 01-11-2018 IPR020845 AMP-binding, conserved site AFULGI_00000870 21720a5d2a60528c4f29e7e936f4ba07 542 SUPERFAMILY SSF56801 17 540 5.49E-140 T 01-11-2018 AFULGI_00016460 2cee7b2e07d99c0da641e96307893996 370 SUPERFAMILY SSF52540 11 201 9.57E-16 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00016460 2cee7b2e07d99c0da641e96307893996 370 Gene3D G3DSA:3.40.50.300 6 198 7.6E-18 T 01-11-2018 AFULGI_00003730 211afc241e0eb2c9f28169674a2f90d0 183 ProSitePatterns PS00351 Transcription factor TFIID repeat signature. 128 177 - T 01-11-2018 IPR030491 TATA-box binding protein, conserved site AFULGI_00003730 211afc241e0eb2c9f28169674a2f90d0 183 Hamap MF_00408 TATA-box-binding protein [tbp]. 2 183 41.561 T 01-11-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 AFULGI_00003730 211afc241e0eb2c9f28169674a2f90d0 183 Gene3D G3DSA:3.30.310.10 8 173 3.3E-67 T 01-11-2018 IPR012295 TBP domain superfamily AFULGI_00003730 211afc241e0eb2c9f28169674a2f90d0 183 Gene3D G3DSA:3.30.310.10 13 99 3.3E-67 T 01-11-2018 IPR012295 TBP domain superfamily AFULGI_00003730 211afc241e0eb2c9f28169674a2f90d0 183 PRINTS PR00686 Transcription initiation factor TFIID signature 51 69 3.8E-44 T 01-11-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 AFULGI_00003730 211afc241e0eb2c9f28169674a2f90d0 183 PRINTS PR00686 Transcription initiation factor TFIID signature 32 51 3.8E-44 T 01-11-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 AFULGI_00003730 211afc241e0eb2c9f28169674a2f90d0 183 PRINTS PR00686 Transcription initiation factor TFIID signature 8 23 3.8E-44 T 01-11-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 AFULGI_00003730 211afc241e0eb2c9f28169674a2f90d0 183 PRINTS PR00686 Transcription initiation factor TFIID signature 143 159 3.8E-44 T 01-11-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 AFULGI_00003730 211afc241e0eb2c9f28169674a2f90d0 183 PRINTS PR00686 Transcription initiation factor TFIID signature 124 139 3.8E-44 T 01-11-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 AFULGI_00003730 211afc241e0eb2c9f28169674a2f90d0 183 PRINTS PR00686 Transcription initiation factor TFIID signature 99 115 3.8E-44 T 01-11-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 AFULGI_00003730 211afc241e0eb2c9f28169674a2f90d0 183 Pfam PF00352 Transcription factor TFIID (or TATA-binding protein, TBP) 97 178 1.6E-30 T 01-11-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 AFULGI_00003730 211afc241e0eb2c9f28169674a2f90d0 183 Pfam PF00352 Transcription factor TFIID (or TATA-binding protein, TBP) 5 86 1.3E-29 T 01-11-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 AFULGI_00003730 211afc241e0eb2c9f28169674a2f90d0 183 SUPERFAMILY SSF55945 3 91 1.0E-29 T 01-11-2018 AFULGI_00003730 211afc241e0eb2c9f28169674a2f90d0 183 SUPERFAMILY SSF55945 92 181 1.13E-30 T 01-11-2018 AFULGI_00026430 2f5f1013bad03f7edad53220ee410b8b 440 SUPERFAMILY SSF55326 59 220 3.29E-21 T 01-11-2018 IPR036921 PurM-like, N-terminal domain superfamily AFULGI_00026430 2f5f1013bad03f7edad53220ee410b8b 440 PIRSF PIRSF006346 1 440 1.2E-219 T 01-11-2018 IPR009186 Predicted nickel metalloenzyme maturation factor, AIR synthase-related AFULGI_00026430 2f5f1013bad03f7edad53220ee410b8b 440 Pfam PF00586 AIR synthase related protein, N-terminal domain 105 216 2.7E-9 T 01-11-2018 IPR016188 PurM-like, N-terminal domain AFULGI_00026430 2f5f1013bad03f7edad53220ee410b8b 440 SUPERFAMILY SSF56042 224 387 1.36E-22 T 01-11-2018 IPR036676 PurM-like, C-terminal domain superfamily AFULGI_00026430 2f5f1013bad03f7edad53220ee410b8b 440 Gene3D G3DSA:3.90.650.10 224 396 1.6E-18 T 01-11-2018 IPR036676 PurM-like, C-terminal domain superfamily AFULGI_00026430 2f5f1013bad03f7edad53220ee410b8b 440 Pfam PF02769 AIR synthase related protein, C-terminal domain 228 380 3.8E-17 T 01-11-2018 IPR010918 PurM-like, C-terminal domain AFULGI_00026430 2f5f1013bad03f7edad53220ee410b8b 440 Gene3D G3DSA:3.30.1330.10 68 221 2.2E-17 T 01-11-2018 IPR036921 PurM-like, N-terminal domain superfamily AFULGI_00012050 69363b3fc40254d87958d97f628d3168 168 Hamap MF_00635 Probable deoxyuridine 5'-triphosphate nucleotidohydrolase [dut]. 5 163 36.232 T 01-11-2018 IPR023537 Deoxyuridine triphosphate nucleotidohydrolase, archaeal GO:0004170 KEGG: 00240+3.6.1.23|KEGG: 00983+3.6.1.23 AFULGI_00012050 69363b3fc40254d87958d97f628d3168 168 Gene3D G3DSA:2.70.40.10 2 168 2.3E-30 T 01-11-2018 IPR036157 dUTPase-like superfamily AFULGI_00012050 69363b3fc40254d87958d97f628d3168 168 Pfam PF00692 dUTPase 74 152 1.5E-9 T 01-11-2018 IPR029054 dUTPase-like AFULGI_00012050 69363b3fc40254d87958d97f628d3168 168 SUPERFAMILY SSF51283 3 163 5.76E-31 T 01-11-2018 IPR036157 dUTPase-like superfamily AFULGI_00003320 6135a7cfde6e9215260923784d7d6c2b 497 SUPERFAMILY SSF47203 264 476 1.57E-72 T 01-11-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 AFULGI_00003320 6135a7cfde6e9215260923784d7d6c2b 497 Pfam PF03241 4-hydroxyphenylacetate 3-hydroxylase C terminal 281 475 4.1E-71 T 01-11-2018 IPR024719 HpaB/PvcC/4-BUDH C-terminal AFULGI_00003320 6135a7cfde6e9215260923784d7d6c2b 497 Pfam PF11794 4-hydroxyphenylacetate 3-hydroxylase N terminal 4 273 1.0E-109 T 01-11-2018 IPR024674 HpaB/PvcC/4-BUDH N-terminal AFULGI_00003320 6135a7cfde6e9215260923784d7d6c2b 497 PIRSF PIRSF000331 1 486 1.1E-185 T 01-11-2018 IPR004925 HpaB/PvcC/4-BUDH AFULGI_00003320 6135a7cfde6e9215260923784d7d6c2b 497 Gene3D G3DSA:2.40.110.10 144 275 3.2E-48 T 01-11-2018 AFULGI_00003320 6135a7cfde6e9215260923784d7d6c2b 497 Gene3D G3DSA:1.10.3140.10 1 142 4.3E-62 T 01-11-2018 AFULGI_00003320 6135a7cfde6e9215260923784d7d6c2b 497 Gene3D G3DSA:1.20.140.10 277 476 1.2E-82 T 01-11-2018 AFULGI_00003320 6135a7cfde6e9215260923784d7d6c2b 497 SUPERFAMILY SSF56645 1 274 1.13E-91 T 01-11-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 AFULGI_00012470 31945c8f4250cae28d3e2b7da6a1b34c 149 SMART SM00344 4 110 6.7E-49 T 01-11-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 AFULGI_00012470 31945c8f4250cae28d3e2b7da6a1b34c 149 SUPERFAMILY SSF54909 64 148 1.79E-18 T 01-11-2018 IPR011008 Dimeric alpha-beta barrel AFULGI_00012470 31945c8f4250cae28d3e2b7da6a1b34c 149 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 20 31 9.1E-15 T 01-11-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFULGI_00012470 31945c8f4250cae28d3e2b7da6a1b34c 149 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 31 50 9.1E-15 T 01-11-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFULGI_00012470 31945c8f4250cae28d3e2b7da6a1b34c 149 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 4 20 9.1E-15 T 01-11-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFULGI_00012470 31945c8f4250cae28d3e2b7da6a1b34c 149 Gene3D G3DSA:3.30.70.920 56 149 2.9E-21 T 01-11-2018 AFULGI_00012470 31945c8f4250cae28d3e2b7da6a1b34c 149 Pfam PF01037 Lrp/AsnC ligand binding domain 70 139 4.9E-16 T 01-11-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain AFULGI_00012470 31945c8f4250cae28d3e2b7da6a1b34c 149 Gene3D G3DSA:1.10.10.10 1 55 3.0E-18 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00012470 31945c8f4250cae28d3e2b7da6a1b34c 149 SUPERFAMILY SSF46785 3 64 7.53E-16 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00012470 31945c8f4250cae28d3e2b7da6a1b34c 149 Pfam PF13404 AsnC-type helix-turn-helix domain 4 45 1.1E-15 T 01-11-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFULGI_00009180 30728a50be89595c7ced3512359404c1 188 SUPERFAMILY SSF47240 2 139 1.8E-30 T 01-11-2018 IPR009078 Ferritin-like superfamily AFULGI_00009180 30728a50be89595c7ced3512359404c1 188 Gene3D G3DSA:2.20.28.10 143 184 1.2E-12 T 01-11-2018 AFULGI_00009180 30728a50be89595c7ced3512359404c1 188 Gene3D G3DSA:1.20.1260.10 1 142 1.1E-36 T 01-11-2018 IPR012347 Ferritin-like AFULGI_00009180 30728a50be89595c7ced3512359404c1 188 SUPERFAMILY SSF57802 144 182 5.26E-10 T 01-11-2018 AFULGI_00009180 30728a50be89595c7ced3512359404c1 188 Pfam PF02915 Rubrerythrin 5 135 3.4E-30 T 01-11-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 AFULGI_00013310 04f2fb6b89254d036f89cb825f28fefa 211 Pfam PF02811 PHP domain 3 81 7.3E-10 T 01-11-2018 IPR004013 PHP domain GO:0003824 AFULGI_00013310 04f2fb6b89254d036f89cb825f28fefa 211 Gene3D G3DSA:3.20.20.140 1 209 1.2E-50 T 01-11-2018 AFULGI_00013310 04f2fb6b89254d036f89cb825f28fefa 211 SUPERFAMILY SSF89550 1 201 3.14E-41 T 01-11-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 AFULGI_00013310 04f2fb6b89254d036f89cb825f28fefa 211 SMART SM00481 2 78 2.6E-25 T 01-11-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal AFULGI_00014540 1b6e0659557faa3dc1cdeefbe566ee48 505 TIGRFAM TIGR02645 ARCH_P_rylase: putative thymidine phosphorylase 4 492 3.7E-169 T 01-11-2018 IPR013466 Thymidine phosphorylase/AMP phosphorylase GO:0016763 AFULGI_00014540 1b6e0659557faa3dc1cdeefbe566ee48 505 Gene3D G3DSA:2.40.40.20 1 84 5.3E-12 T 01-11-2018 AFULGI_00014540 1b6e0659557faa3dc1cdeefbe566ee48 505 Pfam PF00591 Glycosyl transferase family, a/b domain 160 243 5.8E-9 T 01-11-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 AFULGI_00014540 1b6e0659557faa3dc1cdeefbe566ee48 505 Gene3D G3DSA:3.90.1170.30 411 491 7.2E-26 T 01-11-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 AFULGI_00014540 1b6e0659557faa3dc1cdeefbe566ee48 505 SUPERFAMILY SSF52418 155 402 5.23E-62 T 01-11-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 AFULGI_00014540 1b6e0659557faa3dc1cdeefbe566ee48 505 Gene3D G3DSA:3.40.1030.10 154 410 2.1E-84 T 01-11-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 AFULGI_00014540 1b6e0659557faa3dc1cdeefbe566ee48 505 Pfam PF02885 Glycosyl transferase family, helical bundle domain 90 149 8.4E-11 T 01-11-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 AFULGI_00014540 1b6e0659557faa3dc1cdeefbe566ee48 505 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 194 209 - T 01-11-2018 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 AFULGI_00014540 1b6e0659557faa3dc1cdeefbe566ee48 505 PIRSF PIRSF000478 85 499 3.7E-112 T 01-11-2018 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 AFULGI_00014540 1b6e0659557faa3dc1cdeefbe566ee48 505 SMART SM00941 422 489 3.7E-21 T 01-11-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 AFULGI_00014540 1b6e0659557faa3dc1cdeefbe566ee48 505 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 422 486 2.1E-16 T 01-11-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 AFULGI_00014540 1b6e0659557faa3dc1cdeefbe566ee48 505 TIGRFAM TIGR03327 AMP_phos: AMP phosphorylase 3 498 4.9E-196 T 01-11-2018 IPR017713 AMP phosphorylase GO:0009032|GO:0046125 MetaCyc: PWY-5532 AFULGI_00014540 1b6e0659557faa3dc1cdeefbe566ee48 505 SUPERFAMILY SSF47648 87 154 6.41E-14 T 01-11-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 AFULGI_00014540 1b6e0659557faa3dc1cdeefbe566ee48 505 SUPERFAMILY SSF54680 409 496 9.03E-19 T 01-11-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 AFULGI_00014540 1b6e0659557faa3dc1cdeefbe566ee48 505 Hamap MF_02132 AMP phosphorylase. 1 501 45.11 T 01-11-2018 IPR017713 AMP phosphorylase GO:0009032|GO:0046125 MetaCyc: PWY-5532 AFULGI_00014540 1b6e0659557faa3dc1cdeefbe566ee48 505 Gene3D G3DSA:1.20.970.10 85 152 1.4E-18 T 01-11-2018 AFULGI_00023340 31d586b7eb711c2416e7e88111421dbb 88 Hamap MF_00410 50S ribosomal protein L31e [rpl31e]. 3 88 24.148 T 01-11-2018 IPR000054 Ribosomal protein L31e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00023340 31d586b7eb711c2416e7e88111421dbb 88 SUPERFAMILY SSF54575 5 87 3.27E-26 T 01-11-2018 IPR023621 Ribosomal protein L31e domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00023340 31d586b7eb711c2416e7e88111421dbb 88 ProDom PD006030 RIBOSOMAL 60S L31 RIBONUCLEOPROTEIN L31E 50S L31 SUBUNIT STRAIN PHOSPHORYLATION 5 59 4.0E-24 T 01-11-2018 IPR000054 Ribosomal protein L31e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00023340 31d586b7eb711c2416e7e88111421dbb 88 Gene3D G3DSA:3.10.440.10 1 88 2.4E-31 T 01-11-2018 IPR023621 Ribosomal protein L31e domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00023340 31d586b7eb711c2416e7e88111421dbb 88 Pfam PF01198 Ribosomal protein L31e 5 74 9.2E-13 T 01-11-2018 IPR000054 Ribosomal protein L31e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00023340 31d586b7eb711c2416e7e88111421dbb 88 SMART SM01380 3 84 4.8E-30 T 01-11-2018 IPR000054 Ribosomal protein L31e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00023340 31d586b7eb711c2416e7e88111421dbb 88 ProSitePatterns PS01144 Ribosomal protein L31e signature. 49 63 - T 01-11-2018 IPR020052 Ribosomal protein L31e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00004660 63f55e8e409bb985c9de4a3a2a28a50b 134 ProDom PD016056 UPF0216 PYRAB16100 PH0358 MTH949 MK1676 AF0460 PF0452 MJ1224 3 133 7.0E-72 T 01-11-2018 IPR002746 Uncharacterised protein family UPF0216 AFULGI_00004660 63f55e8e409bb985c9de4a3a2a28a50b 134 Hamap MF_00585 UPF0216 protein . 2 132 25.675 T 01-11-2018 IPR002746 Uncharacterised protein family UPF0216 AFULGI_00004660 63f55e8e409bb985c9de4a3a2a28a50b 134 Pfam PF01886 Protein of unknown function DUF61 3 129 3.3E-40 T 01-11-2018 IPR002746 Uncharacterised protein family UPF0216 AFULGI_00004660 63f55e8e409bb985c9de4a3a2a28a50b 134 PIRSF PIRSF005264 1 134 9.3E-55 T 01-11-2018 IPR002746 Uncharacterised protein family UPF0216 AFULGI_00015060 88c155837bb9962f9d5fdbfb236d8df2 319 Pfam PF01877 RNA binding 186 290 4.5E-13 T 01-11-2018 IPR002739 Uncharacterised protein family UPF0201 AFULGI_00015060 88c155837bb9962f9d5fdbfb236d8df2 319 Pfam PF13207 AAA domain 7 139 1.0E-19 T 01-11-2018 AFULGI_00015060 88c155837bb9962f9d5fdbfb236d8df2 319 Gene3D G3DSA:3.30.1440.10 181 309 8.0E-46 T 01-11-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00015060 88c155837bb9962f9d5fdbfb236d8df2 319 Hamap MF_01111 UPF0200 protein . 3 182 33.903 T 01-11-2018 IPR022970 Nucleoside triphosphate hydrolase-related AFULGI_00015060 88c155837bb9962f9d5fdbfb236d8df2 319 SUPERFAMILY SSF55282 186 317 2.18E-36 T 01-11-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00015060 88c155837bb9962f9d5fdbfb236d8df2 319 SUPERFAMILY SSF52540 1 183 1.87E-20 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00015060 88c155837bb9962f9d5fdbfb236d8df2 319 Gene3D G3DSA:3.40.50.300 1 180 1.7E-49 T 01-11-2018 AFULGI_00015060 88c155837bb9962f9d5fdbfb236d8df2 319 Hamap MF_01112 UPF0201 protein . 185 311 23.578 T 01-11-2018 IPR002739 Uncharacterised protein family UPF0201 AFULGI_00008030 df5be8b30c48b8aa6c48156ee514f395 298 Pfam PF01888 CbiD 38 245 1.2E-40 T 01-11-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 AFULGI_00008030 df5be8b30c48b8aa6c48156ee514f395 298 Gene3D G3DSA:3.30.2110.10 40 192 3.2E-53 T 01-11-2018 IPR036074 CbiD superfamily GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 AFULGI_00008030 df5be8b30c48b8aa6c48156ee514f395 298 SUPERFAMILY SSF111342 1 274 1.44E-75 T 01-11-2018 IPR036074 CbiD superfamily GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 AFULGI_00008030 df5be8b30c48b8aa6c48156ee514f395 298 Gene3D G3DSA:3.40.50.10720 193 282 2.1E-56 T 01-11-2018 AFULGI_00008030 df5be8b30c48b8aa6c48156ee514f395 298 Gene3D G3DSA:3.30.1990.10 1 39 1.3E-29 T 01-11-2018 AFULGI_00008030 df5be8b30c48b8aa6c48156ee514f395 298 Hamap MF_00787 Cobalt-precorrin-5B C(1)-methyltransferase [cbiD]. 38 292 16.388 T 01-11-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 AFULGI_00009030 c3b91684f9c21e01ca2948cb9398f635 619 SUPERFAMILY SSF50998 167 616 1.49E-12 T 01-11-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily AFULGI_00009030 c3b91684f9c21e01ca2948cb9398f635 619 Pfam PF09826 Beta propeller domain 95 608 9.6E-109 T 01-11-2018 IPR019198 Beta propeller domain-containing family AFULGI_00009030 c3b91684f9c21e01ca2948cb9398f635 619 PIRSF PIRSF006425 1 619 0.0 T 01-11-2018 IPR014441 Uncharacterised conserved protein UCP006425, beta-propeller-type AFULGI_00003870 3f3ab231f61ff56d32c4f1126c49bff0 195 Hamap MF_01214 PyrE-like protein. 1 195 35.035 T 01-11-2018 IPR022854 PyrE-like AFULGI_00003870 3f3ab231f61ff56d32c4f1126c49bff0 195 Pfam PF00156 Phosphoribosyl transferase domain 60 180 9.5E-20 T 01-11-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 AFULGI_00003870 3f3ab231f61ff56d32c4f1126c49bff0 195 SUPERFAMILY SSF53271 44 185 3.15E-27 T 01-11-2018 IPR029057 Phosphoribosyltransferase-like AFULGI_00003870 3f3ab231f61ff56d32c4f1126c49bff0 195 Gene3D G3DSA:3.40.50.2020 42 195 9.5E-33 T 01-11-2018 AFULGI_00002050 728ef7ab2b99737f6e1ecacbbe1d2ab9 499 TIGRFAM TIGR02090 LEU1_arch: isopropylmalate/citramalate/homocitrate synthases 4 367 1.5E-155 T 01-11-2018 IPR011830 Isopropylmalate/citramalate/homocitrate synthase GO:0019752|GO:0046912 AFULGI_00002050 728ef7ab2b99737f6e1ecacbbe1d2ab9 499 Pfam PF00682 HMGL-like 4 261 1.7E-89 T 01-11-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 AFULGI_00002050 728ef7ab2b99737f6e1ecacbbe1d2ab9 499 Pfam PF08502 LeuA allosteric (dimerisation) domain 359 492 2.2E-34 T 01-11-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 AFULGI_00002050 728ef7ab2b99737f6e1ecacbbe1d2ab9 499 SMART SM00917 358 492 4.5E-29 T 01-11-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 AFULGI_00002050 728ef7ab2b99737f6e1ecacbbe1d2ab9 499 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 11 27 - T 01-11-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 AFULGI_00002050 728ef7ab2b99737f6e1ecacbbe1d2ab9 499 SUPERFAMILY SSF51569 2 279 6.23E-97 T 01-11-2018 AFULGI_00002050 728ef7ab2b99737f6e1ecacbbe1d2ab9 499 SUPERFAMILY SSF110921 387 491 2.75E-21 T 01-11-2018 IPR036230 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain superfamily KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 AFULGI_00002050 728ef7ab2b99737f6e1ecacbbe1d2ab9 499 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 190 203 - T 01-11-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 AFULGI_00002050 728ef7ab2b99737f6e1ecacbbe1d2ab9 499 Gene3D G3DSA:3.30.160.270 386 493 4.6E-12 T 01-11-2018 AFULGI_00002050 728ef7ab2b99737f6e1ecacbbe1d2ab9 499 Gene3D G3DSA:3.20.20.70 1 264 2.0E-99 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFULGI_00002050 728ef7ab2b99737f6e1ecacbbe1d2ab9 499 Gene3D G3DSA:1.10.238.260 268 385 1.5E-33 T 01-11-2018 AFULGI_00014220 63e71d9899d0a81bf3d8d30f76f1ebde 325 Gene3D G3DSA:2.50.20.10 18 210 2.7E-38 T 01-11-2018 AFULGI_00014220 63e71d9899d0a81bf3d8d30f76f1ebde 325 Pfam PF14285 Domain of unknown function (DUF4367) 237 324 2.9E-12 T 01-11-2018 IPR025377 Domain of unknown function DUF4367 AFULGI_00014220 63e71d9899d0a81bf3d8d30f76f1ebde 325 SUPERFAMILY SSF89392 24 207 3.77E-31 T 01-11-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX AFULGI_00014220 63e71d9899d0a81bf3d8d30f76f1ebde 325 Pfam PF17131 Outer membrane lipoprotein-sorting protein 79 168 1.0E-8 T 01-11-2018 IPR033399 Putative outer membrane lipoprotein-sorting protein AFULGI_00019340 bdfe28805201af6f15bdda0667571feb 248 SUPERFAMILY SSF52540 1 227 3.89E-39 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00019340 bdfe28805201af6f15bdda0667571feb 248 PIRSF PIRSF005647 1 248 2.6E-85 T 01-11-2018 IPR014433 Nickel insertion ATPase/GTPase (CO dehydrogenase maturation factor), CooC type AFULGI_00019340 bdfe28805201af6f15bdda0667571feb 248 Gene3D G3DSA:3.40.50.300 1 248 3.9E-55 T 01-11-2018 AFULGI_00019340 bdfe28805201af6f15bdda0667571feb 248 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 3 225 4.1E-23 T 01-11-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain AFULGI_00022710 131d13d61a8811974c5914de4b610f94 219 Gene3D G3DSA:3.40.430.10 1 219 1.1E-70 T 01-11-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 AFULGI_00022710 131d13d61a8811974c5914de4b610f94 219 Pfam PF01872 RibD C-terminal domain 3 212 3.1E-66 T 01-11-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 AFULGI_00022710 131d13d61a8811974c5914de4b610f94 219 TIGRFAM TIGR00227 ribD_Cterm: riboflavin-specific deaminase C-terminal domain 1 216 2.5E-82 T 01-11-2018 IPR011549 Riboflavin-specific deaminase, C-terminal GO:0008703|GO:0009231|GO:0050661|GO:0055114 AFULGI_00022710 131d13d61a8811974c5914de4b610f94 219 TIGRFAM TIGR01508 rib_reduct_arch: diaminohydroxyphosphoribosylaminopyrimidine reductase 3 216 1.3E-97 T 01-11-2018 IPR006401 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 1-reductase, archaeal GO:0016491|GO:0055114 KEGG: 00740+1.1.1.302|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AFULGI_00022710 131d13d61a8811974c5914de4b610f94 219 SUPERFAMILY SSF53597 1 214 5.37E-55 T 01-11-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 AFULGI_00004670 28ba2f991aff8aabd0d76cc585258286 251 Gene3D G3DSA:3.40.50.10790 1 153 3.4E-55 T 01-11-2018 IPR023228 S-adenosyl-l-methionine hydroxide adenosyltransferase, N-terminal AFULGI_00004670 28ba2f991aff8aabd0d76cc585258286 251 Pfam PF01887 S-adenosyl-l-methionine hydroxide adenosyltransferase 4 242 2.1E-76 T 01-11-2018 IPR002747 SAM-dependent chlorinase/fluorinase AFULGI_00004670 28ba2f991aff8aabd0d76cc585258286 251 Gene3D G3DSA:2.40.30.90 162 245 3.0E-22 T 01-11-2018 IPR023227 S-adenosyl-l-methionine hydroxide adenosyltransferase, C-terminal AFULGI_00004670 28ba2f991aff8aabd0d76cc585258286 251 SUPERFAMILY SSF101852 160 245 1.31E-21 T 01-11-2018 IPR023227 S-adenosyl-l-methionine hydroxide adenosyltransferase, C-terminal AFULGI_00004670 28ba2f991aff8aabd0d76cc585258286 251 PIRSF PIRSF006779 1 251 8.1E-90 T 01-11-2018 IPR002747 SAM-dependent chlorinase/fluorinase AFULGI_00004670 28ba2f991aff8aabd0d76cc585258286 251 SUPERFAMILY SSF102522 1 152 2.22E-51 T 01-11-2018 IPR023228 S-adenosyl-l-methionine hydroxide adenosyltransferase, N-terminal AFULGI_00020060 04363434cb62bb627a604ab0ee0778d0 211 Pfam PF03591 AzlC protein 11 141 1.0E-35 T 01-11-2018 IPR011606 Branched-chain amino acid transport, permease AFULGI_00018690 29269d0595a38155619a136e670ddcf6 502 Pfam PF03601 Conserved hypothetical protein 698 143 469 2.2E-23 T 01-11-2018 IPR018383 Uncharacterised protein family UPF0324, prokaryote GO:0016021 AFULGI_00018690 29269d0595a38155619a136e670ddcf6 502 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 323 492 6.0E-95 T 01-11-2018 AFULGI_00021510 be8bd792d4080ffb6fc37b3922cde1fb 142 PIRSF PIRSF002133 14 142 2.4E-34 T 01-11-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFULGI_00021510 be8bd792d4080ffb6fc37b3922cde1fb 142 SUPERFAMILY SSF50249 18 140 1.37E-35 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold AFULGI_00021510 be8bd792d4080ffb6fc37b3922cde1fb 142 TIGRFAM TIGR00982 uS12_E_A: ribosomal protein uS12 4 142 1.2E-83 T 01-11-2018 IPR005680 Ribosomal protein S23, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00021510 be8bd792d4080ffb6fc37b3922cde1fb 142 Pfam PF00164 Ribosomal protein S12/S23 27 139 1.5E-48 T 01-11-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFULGI_00021510 be8bd792d4080ffb6fc37b3922cde1fb 142 Gene3D G3DSA:2.40.50.140 23 141 1.2E-50 T 01-11-2018 AFULGI_00021510 be8bd792d4080ffb6fc37b3922cde1fb 142 ProSitePatterns PS00055 Ribosomal protein S12 signature. 58 65 - T 01-11-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFULGI_00021510 be8bd792d4080ffb6fc37b3922cde1fb 142 Hamap MF_00403_A 30S ribosomal protein S12 [rpsL]. 1 142 43.215 T 01-11-2018 IPR022863 Ribosomal protein S12, archaea AFULGI_00020570 7a5ee501311376c44b9103bfe993ece3 178 SUPERFAMILY SSF54791 3 72 6.24E-12 T 01-11-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 AFULGI_00020570 7a5ee501311376c44b9103bfe993ece3 178 TIGRFAM TIGR03665 arCOG04150: arCOG04150 universal archaeal KH domain protein 6 174 8.2E-65 T 01-11-2018 IPR019964 KH domain protein, archaea AFULGI_00020570 7a5ee501311376c44b9103bfe993ece3 178 Pfam PF00013 KH domain 4 46 3.9E-8 T 01-11-2018 IPR004088 K Homology domain, type 1 GO:0003723 AFULGI_00020570 7a5ee501311376c44b9103bfe993ece3 178 Pfam PF00013 KH domain 101 148 1.5E-8 T 01-11-2018 IPR004088 K Homology domain, type 1 GO:0003723 AFULGI_00020570 7a5ee501311376c44b9103bfe993ece3 178 Gene3D G3DSA:3.30.1370.10 2 78 1.8E-23 T 01-11-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 AFULGI_00020570 7a5ee501311376c44b9103bfe993ece3 178 Gene3D G3DSA:3.30.1370.10 79 177 8.6E-33 T 01-11-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 AFULGI_00020570 7a5ee501311376c44b9103bfe993ece3 178 SUPERFAMILY SSF54791 97 171 3.36E-20 T 01-11-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 AFULGI_00020570 7a5ee501311376c44b9103bfe993ece3 178 SMART SM00322 2 65 2.0E-5 T 01-11-2018 IPR004087 K Homology domain GO:0003676 AFULGI_00020570 7a5ee501311376c44b9103bfe993ece3 178 SMART SM00322 81 152 7.2E-11 T 01-11-2018 IPR004087 K Homology domain GO:0003676 AFULGI_00015100 d504013f5f521f0bd899b3c25dee0bff 613 Gene3D G3DSA:2.130.10.10 267 386 5.2E-27 T 01-11-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 AFULGI_00015100 d504013f5f521f0bd899b3c25dee0bff 613 SUPERFAMILY SSF50998 13 275 4.71E-29 T 01-11-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily AFULGI_00015100 d504013f5f521f0bd899b3c25dee0bff 613 Pfam PF13360 PQQ-like domain 80 204 2.2E-10 T 01-11-2018 IPR002372 Pyrrolo-quinoline quinone repeat AFULGI_00015100 d504013f5f521f0bd899b3c25dee0bff 613 Pfam PF13360 PQQ-like domain 245 374 2.1E-17 T 01-11-2018 IPR002372 Pyrrolo-quinoline quinone repeat AFULGI_00015100 d504013f5f521f0bd899b3c25dee0bff 613 SMART SM00564 188 222 83.0 T 01-11-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat AFULGI_00015100 d504013f5f521f0bd899b3c25dee0bff 613 SMART SM00564 355 385 210.0 T 01-11-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat AFULGI_00015100 d504013f5f521f0bd899b3c25dee0bff 613 SMART SM00564 268 298 0.65 T 01-11-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat AFULGI_00015100 d504013f5f521f0bd899b3c25dee0bff 613 SMART SM00564 231 260 5.8 T 01-11-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat AFULGI_00015100 d504013f5f521f0bd899b3c25dee0bff 613 SMART SM00564 102 133 0.097 T 01-11-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat AFULGI_00015100 d504013f5f521f0bd899b3c25dee0bff 613 SMART SM00564 307 340 1.4E-6 T 01-11-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat AFULGI_00015100 d504013f5f521f0bd899b3c25dee0bff 613 SMART SM00564 146 178 4.1E-4 T 01-11-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat AFULGI_00015100 d504013f5f521f0bd899b3c25dee0bff 613 SMART SM00564 56 94 150.0 T 01-11-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat AFULGI_00015100 d504013f5f521f0bd899b3c25dee0bff 613 Gene3D G3DSA:2.40.128.630 30 137 1.2E-9 T 01-11-2018 AFULGI_00015100 d504013f5f521f0bd899b3c25dee0bff 613 SUPERFAMILY SSF50998 218 384 8.79E-30 T 01-11-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily AFULGI_00015100 d504013f5f521f0bd899b3c25dee0bff 613 Gene3D G3DSA:2.130.10.10 140 266 3.4E-21 T 01-11-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 AFULGI_00015100 d504013f5f521f0bd899b3c25dee0bff 613 Gene3D G3DSA:3.10.20.490 397 490 2.7E-5 T 01-11-2018 AFULGI_00025210 df5288626c58f7f94cd9d1da55b6056a 115 Gene3D G3DSA:3.30.1420.10 1 45 1.7E-27 T 01-11-2018 AFULGI_00025210 df5288626c58f7f94cd9d1da55b6056a 115 Pfam PF04358 DsrC like protein 5 115 3.6E-42 T 01-11-2018 IPR007453 Sulphur transfer protein DsrC/TusE AFULGI_00025210 df5288626c58f7f94cd9d1da55b6056a 115 SUPERFAMILY SSF69721 2 115 1.1E-39 T 01-11-2018 IPR025526 DsrC-like domain superfamily AFULGI_00025210 df5288626c58f7f94cd9d1da55b6056a 115 PIRSF PIRSF006223 4 115 3.3E-40 T 01-11-2018 IPR007453 Sulphur transfer protein DsrC/TusE AFULGI_00025210 df5288626c58f7f94cd9d1da55b6056a 115 TIGRFAM TIGR03342 dsrC_tusE_dsvC: sulfur relay protein, TusE/DsrC/DsvC family 4 115 3.1E-46 T 01-11-2018 IPR007453 Sulphur transfer protein DsrC/TusE AFULGI_00025210 df5288626c58f7f94cd9d1da55b6056a 115 Gene3D G3DSA:1.10.10.370 46 115 2.2E-33 T 01-11-2018 AFULGI_00010410 6c7765652675082ed77e76213537b66a 429 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 1.2E-14 T 01-11-2018 AFULGI_00010410 6c7765652675082ed77e76213537b66a 429 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 271 278 1.2E-14 T 01-11-2018 AFULGI_00010410 6c7765652675082ed77e76213537b66a 429 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 146 171 1.2E-14 T 01-11-2018 AFULGI_00010410 6c7765652675082ed77e76213537b66a 429 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 232 246 1.2E-14 T 01-11-2018 AFULGI_00010410 6c7765652675082ed77e76213537b66a 429 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 231 247 3.7E-20 T 01-11-2018 AFULGI_00010410 6c7765652675082ed77e76213537b66a 429 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 256 278 3.7E-20 T 01-11-2018 AFULGI_00010410 6c7765652675082ed77e76213537b66a 429 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 146 164 3.7E-20 T 01-11-2018 AFULGI_00010410 6c7765652675082ed77e76213537b66a 429 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 100 118 3.7E-20 T 01-11-2018 AFULGI_00010410 6c7765652675082ed77e76213537b66a 429 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 3.7E-20 T 01-11-2018 AFULGI_00010410 6c7765652675082ed77e76213537b66a 429 Gene3D G3DSA:3.50.50.60 36 240 5.7E-93 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFULGI_00010410 6c7765652675082ed77e76213537b66a 429 SUPERFAMILY SSF51905 1 190 8.19E-43 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFULGI_00010410 6c7765652675082ed77e76213537b66a 429 Gene3D G3DSA:3.50.50.60 5 310 5.7E-93 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFULGI_00010410 6c7765652675082ed77e76213537b66a 429 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 299 5.1E-57 T 01-11-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFULGI_00010410 6c7765652675082ed77e76213537b66a 429 SUPERFAMILY SSF51905 145 310 2.16E-33 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFULGI_00014350 738102621fe3c43f7415256ffc8473c6 505 Gene3D G3DSA:3.30.420.40 2 256 3.4E-59 T 01-11-2018 AFULGI_00014350 738102621fe3c43f7415256ffc8473c6 505 SUPERFAMILY SSF53067 258 497 2.36E-47 T 01-11-2018 AFULGI_00014350 738102621fe3c43f7415256ffc8473c6 505 SUPERFAMILY SSF53067 4 259 6.39E-47 T 01-11-2018 AFULGI_00014350 738102621fe3c43f7415256ffc8473c6 505 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 269 450 1.5E-21 T 01-11-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 AFULGI_00014350 738102621fe3c43f7415256ffc8473c6 505 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 4 256 4.7E-40 T 01-11-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 AFULGI_00014350 738102621fe3c43f7415256ffc8473c6 505 PIRSF PIRSF000538 1 502 2.7E-99 T 01-11-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 AFULGI_00014350 738102621fe3c43f7415256ffc8473c6 505 Gene3D G3DSA:3.30.420.40 258 505 2.0E-58 T 01-11-2018 AFULGI_00014910 1ba541f27cbc3550e2be484142c0f29d 231 Pfam PF01292 Prokaryotic cytochrome b561 13 211 9.0E-25 T 01-11-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 AFULGI_00014910 1ba541f27cbc3550e2be484142c0f29d 231 Gene3D G3DSA:1.20.950.20 7 221 1.3E-13 T 01-11-2018 AFULGI_00014910 1ba541f27cbc3550e2be484142c0f29d 231 SUPERFAMILY SSF81342 10 217 2.28E-22 T 01-11-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 AFULGI_00019200 159fbcecfe5fbf730f0daab646db5d62 433 Gene3D G3DSA:3.40.50.12780 2 325 1.2E-126 T 01-11-2018 AFULGI_00019200 159fbcecfe5fbf730f0daab646db5d62 433 Pfam PF14535 AMP-binding enzyme C-terminal domain 334 431 8.7E-32 T 01-11-2018 IPR028154 AMP-dependent ligase, C-terminal AFULGI_00019200 159fbcecfe5fbf730f0daab646db5d62 433 Pfam PF00501 AMP-binding enzyme 90 333 9.7E-19 T 01-11-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFULGI_00019200 159fbcecfe5fbf730f0daab646db5d62 433 PIRSF PIRSF006444 1 433 6.8E-207 T 01-11-2018 IPR011880 Phenylacetate-CoA ligase GO:0010124|GO:0047475 KEGG: 00360+6.2.1.30|MetaCyc: PWY-1341|MetaCyc: PWY-6318|MetaCyc: PWY-7716 AFULGI_00019200 159fbcecfe5fbf730f0daab646db5d62 433 SUPERFAMILY SSF56801 30 388 8.9E-67 T 01-11-2018 AFULGI_00019200 159fbcecfe5fbf730f0daab646db5d62 433 Gene3D G3DSA:3.30.300.30 326 433 2.0E-34 T 01-11-2018 AFULGI_00011230 a8dd764244ccdc117182f6f52c083290 480 Gene3D G3DSA:2.40.110.10 141 268 8.1E-49 T 01-11-2018 AFULGI_00011230 a8dd764244ccdc117182f6f52c083290 480 Pfam PF11794 4-hydroxyphenylacetate 3-hydroxylase N terminal 3 266 2.0E-97 T 01-11-2018 IPR024674 HpaB/PvcC/4-BUDH N-terminal AFULGI_00011230 a8dd764244ccdc117182f6f52c083290 480 Gene3D G3DSA:1.10.3140.10 1 140 1.5E-51 T 01-11-2018 AFULGI_00011230 a8dd764244ccdc117182f6f52c083290 480 Gene3D G3DSA:1.20.140.10 270 474 8.6E-70 T 01-11-2018 AFULGI_00011230 a8dd764244ccdc117182f6f52c083290 480 PIRSF PIRSF000331 1 480 8.3E-165 T 01-11-2018 IPR004925 HpaB/PvcC/4-BUDH AFULGI_00011230 a8dd764244ccdc117182f6f52c083290 480 Pfam PF03241 4-hydroxyphenylacetate 3-hydroxylase C terminal 276 470 1.2E-62 T 01-11-2018 IPR024719 HpaB/PvcC/4-BUDH C-terminal AFULGI_00011230 a8dd764244ccdc117182f6f52c083290 480 SUPERFAMILY SSF56645 1 267 3.93E-78 T 01-11-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 AFULGI_00011230 a8dd764244ccdc117182f6f52c083290 480 SUPERFAMILY SSF47203 257 473 1.46E-62 T 01-11-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 AFULGI_00002010 7521fa5d1af14ba088546a923e539897 109 Pfam PF01849 NAC domain 6 63 5.1E-16 T 01-11-2018 IPR002715 Nascent polypeptide-associated complex NAC domain AFULGI_00002010 7521fa5d1af14ba088546a923e539897 109 Gene3D G3DSA:2.20.70.30 10 67 3.6E-19 T 01-11-2018 IPR038187 NAC A/B domain superfamily AFULGI_00002010 7521fa5d1af14ba088546a923e539897 109 SMART SM01407 6 64 1.7E-21 T 01-11-2018 IPR002715 Nascent polypeptide-associated complex NAC domain AFULGI_00002010 7521fa5d1af14ba088546a923e539897 109 Hamap MF_00814 Nascent polypeptide-associated complex protein [nac]. 7 108 21.427 T 01-11-2018 IPR005231 Nascent polypeptide-associated complex (NAC), archaeal GO:0003723 AFULGI_00002010 7521fa5d1af14ba088546a923e539897 109 Gene3D G3DSA:1.10.8.10 69 108 1.4E-18 T 01-11-2018 AFULGI_00002010 7521fa5d1af14ba088546a923e539897 109 TIGRFAM TIGR00264 TIGR00264: alpha-NAC homolog 1 109 1.0E-51 T 01-11-2018 IPR005231 Nascent polypeptide-associated complex (NAC), archaeal GO:0003723 AFULGI_00002010 7521fa5d1af14ba088546a923e539897 109 SUPERFAMILY SSF46934 66 108 1.13E-7 T 01-11-2018 IPR009060 UBA-like superfamily GO:0005515 AFULGI_00026870 9db6dcb097eb395b0dbbead3c0645b34 162 SUPERFAMILY SSF103165 1 160 9.16E-56 T 01-11-2018 IPR036902 Ta1353-like superfamily AFULGI_00026870 9db6dcb097eb395b0dbbead3c0645b34 162 Pfam PF04008 Adenosine specific kinase 6 160 8.1E-58 T 01-11-2018 IPR007153 Adenosine specific kinase AFULGI_00026870 9db6dcb097eb395b0dbbead3c0645b34 162 Gene3D G3DSA:3.40.1520.10 1 162 4.8E-63 T 01-11-2018 IPR036902 Ta1353-like superfamily AFULGI_00023750 d0f5f97f675efab843b3cf2031d80c06 238 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 1 230 36.152 T 01-11-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AFULGI_00023750 d0f5f97f675efab843b3cf2031d80c06 238 SUPERFAMILY SSF55821 4 225 6.18E-62 T 01-11-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily AFULGI_00023750 d0f5f97f675efab843b3cf2031d80c06 238 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 1 226 2.8E-84 T 01-11-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AFULGI_00023750 d0f5f97f675efab843b3cf2031d80c06 238 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 6 224 2.4E-56 T 01-11-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AFULGI_00023750 d0f5f97f675efab843b3cf2031d80c06 238 Gene3D G3DSA:3.90.870.10 4 231 1.6E-70 T 01-11-2018 AFULGI_00013690 eae6163358ec905f46ace0409045f195 139 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 26 100 6.4E-15 T 01-11-2018 IPR002831 Transcription regulator TrmB, N-terminal AFULGI_00013690 eae6163358ec905f46ace0409045f195 139 SUPERFAMILY SSF46785 28 117 1.68E-13 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00013690 eae6163358ec905f46ace0409045f195 139 Gene3D G3DSA:1.10.10.10 11 127 1.6E-33 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00012240 b178dcda0012b7afe47e511e87d6e389 148 SUPERFAMILY SSF102405 1 142 9.92E-33 T 01-11-2018 AFULGI_00012240 b178dcda0012b7afe47e511e87d6e389 148 Pfam PF03641 Possible lysine decarboxylase 42 130 4.6E-7 T 01-11-2018 IPR031100 LOG family AFULGI_00012240 b178dcda0012b7afe47e511e87d6e389 148 Gene3D G3DSA:3.40.50.450 1 145 4.7E-36 T 01-11-2018 AFULGI_00012240 b178dcda0012b7afe47e511e87d6e389 148 TIGRFAM TIGR00725 TIGR00725: TIGR00725 family protein 1 143 1.7E-57 T 01-11-2018 IPR005268 Conserved hypothetical protein CHP00725 AFULGI_00015000 9bd8ed759b4db1e38fa0d0f2c8f27e61 236 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFULGI_00015000 9bd8ed759b4db1e38fa0d0f2c8f27e61 236 SMART SM00382 26 219 4.1E-10 T 01-11-2018 IPR003593 AAA+ ATPase domain AFULGI_00015000 9bd8ed759b4db1e38fa0d0f2c8f27e61 236 Gene3D G3DSA:3.40.50.300 1 235 3.8E-62 T 01-11-2018 AFULGI_00015000 9bd8ed759b4db1e38fa0d0f2c8f27e61 236 Pfam PF00005 ABC transporter 19 162 9.7E-32 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFULGI_00015000 9bd8ed759b4db1e38fa0d0f2c8f27e61 236 SUPERFAMILY SSF52540 3 226 4.97E-57 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00012410 03308b5a9c20cccb1693131bc5d0b78d 241 SUPERFAMILY SSF53448 1 235 2.7E-44 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFULGI_00012410 03308b5a9c20cccb1693131bc5d0b78d 241 Gene3D G3DSA:3.90.550.10 1 240 2.5E-51 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFULGI_00012410 03308b5a9c20cccb1693131bc5d0b78d 241 Pfam PF12804 MobA-like NTP transferase domain 3 118 7.9E-16 T 01-11-2018 IPR025877 MobA-like NTP transferase AFULGI_00017430 94c88c9aee161daa62c6155896b6ad85 339 Gene3D G3DSA:3.90.105.20 106 185 9.8E-64 T 01-11-2018 AFULGI_00017430 94c88c9aee161daa62c6155896b6ad85 339 Gene3D G3DSA:3.30.70.1730 19 209 9.8E-64 T 01-11-2018 AFULGI_00017430 94c88c9aee161daa62c6155896b6ad85 339 Pfam PF00466 Ribosomal protein L10 9 104 1.8E-23 T 01-11-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 AFULGI_00017430 94c88c9aee161daa62c6155896b6ad85 339 Hamap MF_00280 50S ribosomal protein L10 [rpl10]. 5 282 33.521 T 01-11-2018 IPR022909 50S ribosomal protein L10, archaea AFULGI_00017430 94c88c9aee161daa62c6155896b6ad85 339 SUPERFAMILY SSF160369 9 139 1.57E-23 T 01-11-2018 AFULGI_00026410 42c79fcf976b2ea7950fe3eb5fdccf97 291 SUPERFAMILY SSF56281 33 267 1.67E-29 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFULGI_00026410 42c79fcf976b2ea7950fe3eb5fdccf97 291 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 237 279 7.7E-5 T 01-11-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain AFULGI_00026410 42c79fcf976b2ea7950fe3eb5fdccf97 291 Gene3D G3DSA:3.60.15.10 16 180 7.1E-17 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFULGI_00012520 132d097b85a9412ff66c5ce8523be7b2 357 TIGRFAM TIGR01213 pseudo_Pus10arc: tRNA pseudouridine(54/55) synthase 17 356 3.0E-103 T 01-11-2018 IPR005912 tRNA pseudouridine synthase, Pus10 GO:0000049|GO:0001522|GO:0006400|GO:0009982 AFULGI_00012520 132d097b85a9412ff66c5ce8523be7b2 357 Hamap MF_01893 tRNA pseudouridine synthase Pus10 [pus10]. 2 357 52.551 T 01-11-2018 IPR005912 tRNA pseudouridine synthase, Pus10 GO:0000049|GO:0001522|GO:0006400|GO:0009982 AFULGI_00012520 132d097b85a9412ff66c5ce8523be7b2 357 Gene3D G3DSA:3.30.70.3190 250 357 1.3E-28 T 01-11-2018 AFULGI_00012520 132d097b85a9412ff66c5ce8523be7b2 357 SUPERFAMILY SSF55120 246 356 6.91E-15 T 01-11-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFULGI_00012520 132d097b85a9412ff66c5ce8523be7b2 357 Gene3D G3DSA:3.30.70.2510 118 249 6.2E-38 T 01-11-2018 AFULGI_00012520 132d097b85a9412ff66c5ce8523be7b2 357 Pfam PF02926 THUMP domain 18 118 2.5E-18 T 01-11-2018 IPR004114 THUMP domain GO:0003723 AFULGI_00000070 3d298406ea03ff3347aa47fe5ddaeedb 290 Gene3D G3DSA:3.20.20.20 70 263 4.9E-9 T 01-11-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFULGI_00000070 3d298406ea03ff3347aa47fe5ddaeedb 290 PIRSF PIRSF004960 1 290 1.3E-121 T 01-11-2018 IPR023467 Tetrahydromethanopterin S-methyltransferase, subunit H/Methyltransferase Mtx, subunit H GO:0006730|GO:0008168 AFULGI_00000070 3d298406ea03ff3347aa47fe5ddaeedb 290 PIRSF PIRSF500206 1 290 6.2E-128 T 01-11-2018 AFULGI_00000070 3d298406ea03ff3347aa47fe5ddaeedb 290 Pfam PF02007 Tetrahydromethanopterin S-methyltransferase MtrH subunit 6 290 1.1E-132 T 01-11-2018 IPR023467 Tetrahydromethanopterin S-methyltransferase, subunit H/Methyltransferase Mtx, subunit H GO:0006730|GO:0008168 AFULGI_00000070 3d298406ea03ff3347aa47fe5ddaeedb 290 SUPERFAMILY SSF51717 22 257 2.16E-15 T 01-11-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFULGI_00000070 3d298406ea03ff3347aa47fe5ddaeedb 290 ProDom PD009948 METHYLTRANSFERASE SUBUNIT H TRANSFERASE M TETRAHYDROMETHANOPTERIN S-METHYLTRANSFERASE N5-METHYLTETRAHYDROMETHANOPTERIN--COENZYME METHANOGENESIS ONE-CARBON 72 274 6.0E-109 T 01-11-2018 IPR023467 Tetrahydromethanopterin S-methyltransferase, subunit H/Methyltransferase Mtx, subunit H GO:0006730|GO:0008168 AFULGI_00020870 99ade0e739d9909200742c0c7d468a09 347 Gene3D G3DSA:3.30.70.20 19 85 7.4E-12 T 01-11-2018 AFULGI_00020870 99ade0e739d9909200742c0c7d468a09 347 Pfam PF13237 4Fe-4S dicluster domain 27 75 2.0E-6 T 01-11-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFULGI_00020870 99ade0e739d9909200742c0c7d468a09 347 Pfam PF04422 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term 92 165 6.2E-14 T 01-11-2018 IPR007516 Coenzyme F420 hydrogenase/dehydrogenase beta subunit, N-terminal AFULGI_00020870 99ade0e739d9909200742c0c7d468a09 347 SUPERFAMILY SSF54862 27 122 1.83E-12 T 01-11-2018 AFULGI_00020870 99ade0e739d9909200742c0c7d468a09 347 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 64 75 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFULGI_00020870 99ade0e739d9909200742c0c7d468a09 347 Pfam PF04432 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus 173 318 6.4E-38 T 01-11-2018 IPR007525 Coenzyme F420 hydrogenase/dehydrogenase beta subunit, C-terminal AFULGI_00011950 69a2003d4f664810f27ca0f2bcf110d2 178 SUPERFAMILY SSF117457 2 176 1.57E-64 T 01-11-2018 IPR036660 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain superfamily GO:0016836 AFULGI_00011950 69a2003d4f664810f27ca0f2bcf110d2 178 TIGRFAM TIGR00723 ttdB_fumA_fumB: hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type 13 178 5.1E-78 T 01-11-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 AFULGI_00011950 69a2003d4f664810f27ca0f2bcf110d2 178 Gene3D G3DSA:3.20.130.10 1 178 2.6E-84 T 01-11-2018 IPR036660 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain superfamily GO:0016836 AFULGI_00011950 69a2003d4f664810f27ca0f2bcf110d2 178 Pfam PF05683 Fumarase C-terminus 7 177 1.9E-50 T 01-11-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 AFULGI_00011140 041add887d1b7f7c632ab9030c3d84a1 228 SUPERFAMILY SSF52540 3 226 1.33E-78 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00011140 041add887d1b7f7c632ab9030c3d84a1 228 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFULGI_00011140 041add887d1b7f7c632ab9030c3d84a1 228 Pfam PF00005 ABC transporter 23 171 9.6E-38 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFULGI_00011140 041add887d1b7f7c632ab9030c3d84a1 228 Gene3D G3DSA:3.40.50.300 1 227 5.7E-76 T 01-11-2018 AFULGI_00011140 041add887d1b7f7c632ab9030c3d84a1 228 SMART SM00382 32 220 3.6E-19 T 01-11-2018 IPR003593 AAA+ ATPase domain AFULGI_00021680 bbbf779f4e8f08ff8ef07beaaaf616bb 185 Gene3D G3DSA:3.90.930.12 9 92 4.6E-20 T 01-11-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00021680 bbbf779f4e8f08ff8ef07beaaaf616bb 185 ProSitePatterns PS00700 Ribosomal protein L6 signature 2. 163 184 - T 01-11-2018 IPR002359 Ribosomal protein L6, conserved site-2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00021680 bbbf779f4e8f08ff8ef07beaaaf616bb 185 Hamap MF_01365_A 50S ribosomal protein L6 [rplF]. 4 185 37.463 T 01-11-2018 IPR019907 Ribosomal protein L6P, archaea GO:0003735|GO:0005840|GO:0006412|GO:0019843 AFULGI_00021680 bbbf779f4e8f08ff8ef07beaaaf616bb 185 Pfam PF00347 Ribosomal protein L6 15 92 2.2E-15 T 01-11-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00021680 bbbf779f4e8f08ff8ef07beaaaf616bb 185 Pfam PF00347 Ribosomal protein L6 104 178 6.8E-13 T 01-11-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00021680 bbbf779f4e8f08ff8ef07beaaaf616bb 185 PIRSF PIRSF002162 6 185 1.6E-32 T 01-11-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00021680 bbbf779f4e8f08ff8ef07beaaaf616bb 185 TIGRFAM TIGR03653 uL6_arch: ribosomal protein uL6 11 184 9.7E-69 T 01-11-2018 IPR019907 Ribosomal protein L6P, archaea GO:0003735|GO:0005840|GO:0006412|GO:0019843 AFULGI_00021680 bbbf779f4e8f08ff8ef07beaaaf616bb 185 SUPERFAMILY SSF56053 9 92 1.73E-15 T 01-11-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00021680 bbbf779f4e8f08ff8ef07beaaaf616bb 185 Gene3D G3DSA:3.90.930.12 93 185 2.5E-36 T 01-11-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00021680 bbbf779f4e8f08ff8ef07beaaaf616bb 185 SUPERFAMILY SSF56053 93 184 2.02E-29 T 01-11-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00005460 faf2ac3fc1c5cfbf49d4442685688933 150 Pfam PF00467 KOW motif 93 124 5.0E-8 T 01-11-2018 IPR005824 KOW AFULGI_00005460 faf2ac3fc1c5cfbf49d4442685688933 150 Gene3D G3DSA:2.30.30.30 90 149 2.3E-26 T 01-11-2018 IPR014722 Ribosomal protein L2, domain 2 AFULGI_00005460 faf2ac3fc1c5cfbf49d4442685688933 150 SUPERFAMILY SSF82679 3 75 7.06E-5 T 01-11-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 AFULGI_00005460 faf2ac3fc1c5cfbf49d4442685688933 150 Gene3D G3DSA:3.30.70.940 3 89 3.1E-32 T 01-11-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 AFULGI_00005460 faf2ac3fc1c5cfbf49d4442685688933 150 SMART SM00738 1 85 2.2E-26 T 01-11-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 AFULGI_00005460 faf2ac3fc1c5cfbf49d4442685688933 150 SUPERFAMILY SSF50104 58 147 1.89E-18 T 01-11-2018 IPR008991 Translation protein SH3-like domain superfamily AFULGI_00005460 faf2ac3fc1c5cfbf49d4442685688933 150 ProSitePatterns PS01108 Ribosomal protein L24 signature. 94 111 - T 01-11-2018 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFULGI_00005460 faf2ac3fc1c5cfbf49d4442685688933 150 Hamap MF_00950 Transcription elongation factor Spt5 [spt5]. 3 146 40.025 T 01-11-2018 IPR011590 Transcription elongation factor Spt5, archaeal GO:0003746 AFULGI_00005460 faf2ac3fc1c5cfbf49d4442685688933 150 SMART SM00739 90 117 2.0E-6 T 01-11-2018 IPR005824 KOW AFULGI_00005460 faf2ac3fc1c5cfbf49d4442685688933 150 Pfam PF03439 Early transcription elongation factor of RNA pol II, NGN section 3 82 2.9E-25 T 01-11-2018 IPR005100 NGN domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 AFULGI_00005460 faf2ac3fc1c5cfbf49d4442685688933 150 TIGRFAM TIGR00405 KOW_elon_Spt5: transcription elongation factor Spt5 5 149 1.9E-76 T 01-11-2018 IPR011590 Transcription elongation factor Spt5, archaeal GO:0003746 AFULGI_00020800 81532c97b8ae9ad23202601f544750b6 649 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 82 130 1.4E-6 T 01-11-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFULGI_00020800 81532c97b8ae9ad23202601f544750b6 649 Pfam PF00361 Proton-conducting membrane transporter 202 443 2.9E-34 T 01-11-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFULGI_00020800 81532c97b8ae9ad23202601f544750b6 649 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 95 120 5.9E-19 T 01-11-2018 AFULGI_00020800 81532c97b8ae9ad23202601f544750b6 649 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 257 278 5.9E-19 T 01-11-2018 AFULGI_00020800 81532c97b8ae9ad23202601f544750b6 649 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 279 305 5.9E-19 T 01-11-2018 AFULGI_00000220 c183e0bc4bb1b1772cc0f9f1eb58c377 413 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 285 305 - T 01-11-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 AFULGI_00000220 c183e0bc4bb1b1772cc0f9f1eb58c377 413 Gene3D G3DSA:1.20.1090.10 211 412 6.1E-59 T 01-11-2018 AFULGI_00000220 c183e0bc4bb1b1772cc0f9f1eb58c377 413 Gene3D G3DSA:3.40.50.1970 27 209 5.1E-47 T 01-11-2018 AFULGI_00000220 c183e0bc4bb1b1772cc0f9f1eb58c377 413 SUPERFAMILY SSF56796 29 411 2.88E-102 T 01-11-2018 AFULGI_00000220 c183e0bc4bb1b1772cc0f9f1eb58c377 413 Pfam PF00465 Iron-containing alcohol dehydrogenase 34 400 8.6E-101 T 01-11-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 AFULGI_00025950 76790b53af9fe7cc66f084066b6e1e3d 360 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 10 197 5.0E-13 T 01-11-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 AFULGI_00024690 89b8529032230b49726092489b5b386f 395 Gene3D G3DSA:3.30.70.1450 110 190 2.9E-20 T 01-11-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 AFULGI_00024690 89b8529032230b49726092489b5b386f 395 Gene3D G3DSA:3.30.70.1450 313 392 2.6E-18 T 01-11-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 AFULGI_00024690 89b8529032230b49726092489b5b386f 395 SUPERFAMILY SSF116726 304 388 1.83E-18 T 01-11-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 AFULGI_00024690 89b8529032230b49726092489b5b386f 395 Gene3D G3DSA:1.20.58.220 201 312 2.0E-13 T 01-11-2018 IPR038078 PhoU-like domain superfamily AFULGI_00024690 89b8529032230b49726092489b5b386f 395 Gene3D G3DSA:1.20.58.220 2 105 3.8E-14 T 01-11-2018 IPR038078 PhoU-like domain superfamily AFULGI_00024690 89b8529032230b49726092489b5b386f 395 Pfam PF02080 TrkA-C domain 320 387 2.3E-13 T 01-11-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 AFULGI_00024690 89b8529032230b49726092489b5b386f 395 Pfam PF02080 TrkA-C domain 115 184 4.3E-16 T 01-11-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 AFULGI_00024690 89b8529032230b49726092489b5b386f 395 SUPERFAMILY SSF109755 4 115 5.89E-12 T 01-11-2018 AFULGI_00024690 89b8529032230b49726092489b5b386f 395 Pfam PF01895 PhoU domain 10 91 6.1E-7 T 01-11-2018 IPR026022 PhoU domain AFULGI_00024690 89b8529032230b49726092489b5b386f 395 Pfam PF01895 PhoU domain 212 296 2.7E-12 T 01-11-2018 IPR026022 PhoU domain AFULGI_00024690 89b8529032230b49726092489b5b386f 395 SUPERFAMILY SSF116726 101 184 3.4E-19 T 01-11-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 AFULGI_00024690 89b8529032230b49726092489b5b386f 395 SUPERFAMILY SSF109755 202 312 4.97E-13 T 01-11-2018 AFULGI_00017650 a20b9cb131dbd9928898948b9bc66336 194 SUPERFAMILY SSF54001 39 190 1.96E-26 T 01-11-2018 IPR038765 Papain-like cysteine peptidase superfamily AFULGI_00017650 a20b9cb131dbd9928898948b9bc66336 194 Gene3D G3DSA:3.90.1720.10 37 169 3.1E-10 T 01-11-2018 AFULGI_00017650 a20b9cb131dbd9928898948b9bc66336 194 Pfam PF05708 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family 39 190 2.0E-16 T 01-11-2018 IPR024453 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family AFULGI_00011200 952ba1ac8178897c94e6ce9c85aff992 1054 Gene3D G3DSA:1.10.460.10 680 1047 1.9E-165 T 01-11-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 AFULGI_00011200 952ba1ac8178897c94e6ce9c85aff992 1054 SUPERFAMILY SSF56712 502 1052 1.1E-146 T 01-11-2018 IPR023405 DNA topoisomerase, type IA, core domain AFULGI_00011200 952ba1ac8178897c94e6ce9c85aff992 1054 Pfam PF01751 Toprim domain 508 661 1.3E-23 T 01-11-2018 IPR006171 TOPRIM domain AFULGI_00011200 952ba1ac8178897c94e6ce9c85aff992 1054 Gene3D G3DSA:3.40.50.300 246 504 0.0 T 01-11-2018 AFULGI_00011200 952ba1ac8178897c94e6ce9c85aff992 1054 Pfam PF01131 DNA topoisomerase 735 1042 9.2E-59 T 01-11-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 AFULGI_00011200 952ba1ac8178897c94e6ce9c85aff992 1054 Pfam PF01131 DNA topoisomerase 676 732 3.1E-13 T 01-11-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 AFULGI_00011200 952ba1ac8178897c94e6ce9c85aff992 1054 SMART SM00493 506 652 3.1E-39 T 01-11-2018 IPR006171 TOPRIM domain AFULGI_00011200 952ba1ac8178897c94e6ce9c85aff992 1054 SUPERFAMILY SSF52540 252 498 5.0E-48 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00011200 952ba1ac8178897c94e6ce9c85aff992 1054 Gene3D G3DSA:3.40.50.140 505 585 0.0 T 01-11-2018 AFULGI_00011200 952ba1ac8178897c94e6ce9c85aff992 1054 Gene3D G3DSA:2.60.510.20 733 953 1.9E-165 T 01-11-2018 AFULGI_00011200 952ba1ac8178897c94e6ce9c85aff992 1054 Gene3D G3DSA:3.40.50.300 33 245 0.0 T 01-11-2018 AFULGI_00011200 952ba1ac8178897c94e6ce9c85aff992 1054 SMART SM00487 53 252 9.6E-25 T 01-11-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFULGI_00011200 952ba1ac8178897c94e6ce9c85aff992 1054 Hamap MF_01125 Reverse gyrase [rgy]. 1 1054 60.941 T 01-11-2018 IPR005736 Reverse gyrase GO:0003677|GO:0003916|GO:0006265 AFULGI_00011200 952ba1ac8178897c94e6ce9c85aff992 1054 Gene3D G3DSA:1.10.720.70 353 425 0.0 T 01-11-2018 AFULGI_00011200 952ba1ac8178897c94e6ce9c85aff992 1054 SUPERFAMILY SSF52540 3 241 1.18E-41 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00011200 952ba1ac8178897c94e6ce9c85aff992 1054 Gene3D G3DSA:2.20.20.30 1 29 1.2E-7 T 01-11-2018 AFULGI_00011200 952ba1ac8178897c94e6ce9c85aff992 1054 Gene3D G3DSA:1.10.290.10 772 890 1.9E-165 T 01-11-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 AFULGI_00011200 952ba1ac8178897c94e6ce9c85aff992 1054 Gene3D G3DSA:2.20.20.30 32 582 0.0 T 01-11-2018 AFULGI_00011200 952ba1ac8178897c94e6ce9c85aff992 1054 TIGRFAM TIGR01054 rgy: reverse gyrase 1 1053 0.0 T 01-11-2018 IPR005736 Reverse gyrase GO:0003677|GO:0003916|GO:0006265 AFULGI_00011200 952ba1ac8178897c94e6ce9c85aff992 1054 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 969 983 7.5E-27 T 01-11-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 AFULGI_00011200 952ba1ac8178897c94e6ce9c85aff992 1054 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 626 639 7.5E-27 T 01-11-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 AFULGI_00011200 952ba1ac8178897c94e6ce9c85aff992 1054 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 879 895 7.5E-27 T 01-11-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 AFULGI_00011200 952ba1ac8178897c94e6ce9c85aff992 1054 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 804 813 7.5E-27 T 01-11-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 AFULGI_00011200 952ba1ac8178897c94e6ce9c85aff992 1054 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 711 729 7.5E-27 T 01-11-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 AFULGI_00011200 952ba1ac8178897c94e6ce9c85aff992 1054 SMART SM00436 652 738 1.5E-36 T 01-11-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 AFULGI_00011200 952ba1ac8178897c94e6ce9c85aff992 1054 SMART SM00437 762 1006 6.2E-103 T 01-11-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 AFULGI_00011200 952ba1ac8178897c94e6ce9c85aff992 1054 Pfam PF00270 DEAD/DEAH box helicase 59 228 1.0E-11 T 01-11-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 AFULGI_00004990 6f88e19e34c9d810ccbcfb4f20e1e9cb 234 Pfam PF01172 Shwachman-Bodian-Diamond syndrome (SBDS) protein 7 93 1.9E-22 T 01-11-2018 IPR019783 Ribosome maturation protein SBDS, N-terminal AFULGI_00004990 6f88e19e34c9d810ccbcfb4f20e1e9cb 234 ProSitePatterns PS01267 Uncharacterized protein family UPF0023 signature. 36 55 - T 01-11-2018 IPR018023 Ribosome maturation protein SBDS, conserved site AFULGI_00004990 6f88e19e34c9d810ccbcfb4f20e1e9cb 234 SUPERFAMILY SSF89895 2 86 8.37E-25 T 01-11-2018 IPR036786 Ribosome maturation protein SBDS, N-terminal domain superfamily AFULGI_00004990 6f88e19e34c9d810ccbcfb4f20e1e9cb 234 SUPERFAMILY SSF109728 82 154 9.16E-27 T 01-11-2018 IPR037188 Ribosome maturation protein Sdo1/SBDS, central domain superfamily AFULGI_00004990 6f88e19e34c9d810ccbcfb4f20e1e9cb 234 SUPERFAMILY SSF54980 156 227 3.45E-23 T 01-11-2018 IPR035647 EF-G domain III/V-like AFULGI_00004990 6f88e19e34c9d810ccbcfb4f20e1e9cb 234 Gene3D G3DSA:3.30.70.240 162 234 1.0E-30 T 01-11-2018 AFULGI_00004990 6f88e19e34c9d810ccbcfb4f20e1e9cb 234 Pfam PF09377 SBDS protein C-terminal domain 100 217 1.1E-23 T 01-11-2018 IPR018978 Ribosome maturation protein SBDS, C-terminal GO:0042254 AFULGI_00004990 6f88e19e34c9d810ccbcfb4f20e1e9cb 234 TIGRFAM TIGR00291 RNA_SBDS: rRNA metabolism protein, SBDS family 1 231 1.5E-120 T 01-11-2018 IPR002140 Ribosome maturation protein Sdo1/SBDS GO:0042256 AFULGI_00004990 6f88e19e34c9d810ccbcfb4f20e1e9cb 234 Gene3D G3DSA:3.30.1250.10 7 86 2.4E-31 T 01-11-2018 IPR036786 Ribosome maturation protein SBDS, N-terminal domain superfamily AFULGI_00004990 6f88e19e34c9d810ccbcfb4f20e1e9cb 234 Gene3D G3DSA:1.10.10.900 87 161 3.3E-35 T 01-11-2018 IPR037188 Ribosome maturation protein Sdo1/SBDS, central domain superfamily AFULGI_00019380 a3254788b456ab913e8af5b097fc5ab5 73 ProDom PD188822 UPF0330 AF1997 ST1125.1 AF1689 AF1478 C1_0043 PYRAB04040 PF1222 MM2475 MA1514 1 54 3.0E-23 T 01-11-2018 IPR003847 Putative antitoxin AFULGI_00019380 a3254788b456ab913e8af5b097fc5ab5 73 Pfam PF02697 Putative antitoxin 2 67 6.5E-22 T 01-11-2018 IPR003847 Putative antitoxin AFULGI_00019380 a3254788b456ab913e8af5b097fc5ab5 73 Hamap MF_00794 Putative antitoxin . 1 71 16.098 T 01-11-2018 IPR003847 Putative antitoxin AFULGI_00010800 a3fab7e5a3ad94457c0ddecb0601190c 242 Gene3D G3DSA:3.40.50.300 1 240 5.0E-55 T 01-11-2018 AFULGI_00010800 a3fab7e5a3ad94457c0ddecb0601190c 242 Pfam PF00005 ABC transporter 19 164 2.0E-26 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFULGI_00010800 a3fab7e5a3ad94457c0ddecb0601190c 242 SUPERFAMILY SSF52540 2 239 1.44E-55 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00010800 a3fab7e5a3ad94457c0ddecb0601190c 242 SMART SM00382 27 216 5.7E-7 T 01-11-2018 IPR003593 AAA+ ATPase domain AFULGI_00023410 5fc0927ede3a6a01411caba9be0664bf 100 SUPERFAMILY SSF69786 6 96 4.97E-19 T 01-11-2018 IPR036591 YggU-like superfamily AFULGI_00023410 5fc0927ede3a6a01411caba9be0664bf 100 Hamap MF_00634 UPF0235 protein YggU [yggU]. 11 95 16.305 T 01-11-2018 IPR003746 Protein of unknown function DUF167 AFULGI_00023410 5fc0927ede3a6a01411caba9be0664bf 100 TIGRFAM TIGR00251 TIGR00251: TIGR00251 family protein 8 91 9.5E-35 T 01-11-2018 IPR005228 Conserved hypothetical protein CHP00251 AFULGI_00023410 5fc0927ede3a6a01411caba9be0664bf 100 Pfam PF02594 Uncharacterised ACR, YggU family COG1872 15 82 8.9E-19 T 01-11-2018 IPR003746 Protein of unknown function DUF167 AFULGI_00023410 5fc0927ede3a6a01411caba9be0664bf 100 Gene3D G3DSA:3.30.1200.10 3 97 2.9E-26 T 01-11-2018 IPR036591 YggU-like superfamily AFULGI_00023410 5fc0927ede3a6a01411caba9be0664bf 100 SMART SM01152 11 84 1.3E-20 T 01-11-2018 IPR003746 Protein of unknown function DUF167 AFULGI_00016620 7981d5a8f7c123858a764fef8f244627 108 Pfam PF00085 Thioredoxin 3 101 5.7E-27 T 01-11-2018 IPR013766 Thioredoxin domain GO:0045454 AFULGI_00016620 7981d5a8f7c123858a764fef8f244627 108 PRINTS PR00421 Thioredoxin family signature 68 79 2.3E-8 T 01-11-2018 AFULGI_00016620 7981d5a8f7c123858a764fef8f244627 108 PRINTS PR00421 Thioredoxin family signature 21 29 2.3E-8 T 01-11-2018 AFULGI_00016620 7981d5a8f7c123858a764fef8f244627 108 PRINTS PR00421 Thioredoxin family signature 29 38 2.3E-8 T 01-11-2018 AFULGI_00016620 7981d5a8f7c123858a764fef8f244627 108 SUPERFAMILY SSF52833 2 105 2.36E-35 T 01-11-2018 IPR036249 Thioredoxin-like superfamily AFULGI_00016620 7981d5a8f7c123858a764fef8f244627 108 Gene3D G3DSA:3.40.30.10 1 105 1.5E-31 T 01-11-2018 AFULGI_00016620 7981d5a8f7c123858a764fef8f244627 108 PIRSF PIRSF000077 1 104 1.5E-29 T 01-11-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 AFULGI_00016620 7981d5a8f7c123858a764fef8f244627 108 ProSitePatterns PS00194 Thioredoxin family active site. 22 40 - T 01-11-2018 IPR017937 Thioredoxin, conserved site GO:0045454 AFULGI_00016620 7981d5a8f7c123858a764fef8f244627 108 TIGRFAM TIGR01068 thioredoxin: thioredoxin 7 103 1.3E-30 T 01-11-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 AFULGI_00025530 b8f02506a7732d9f1d0726eeb0b41924 503 Pfam PF07690 Major Facilitator Superfamily 20 409 7.0E-48 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFULGI_00025530 b8f02506a7732d9f1d0726eeb0b41924 503 Gene3D G3DSA:1.20.1250.20 260 433 6.4E-20 T 01-11-2018 AFULGI_00025530 b8f02506a7732d9f1d0726eeb0b41924 503 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 15 422 2.4E-91 T 01-11-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 AFULGI_00025530 b8f02506a7732d9f1d0726eeb0b41924 503 PRINTS PR01036 Tetracycline resistance protein TetB signature 138 162 2.0E-8 T 01-11-2018 AFULGI_00025530 b8f02506a7732d9f1d0726eeb0b41924 503 PRINTS PR01036 Tetracycline resistance protein TetB signature 17 41 2.0E-8 T 01-11-2018 AFULGI_00025530 b8f02506a7732d9f1d0726eeb0b41924 503 PRINTS PR01036 Tetracycline resistance protein TetB signature 108 128 2.0E-8 T 01-11-2018 AFULGI_00025530 b8f02506a7732d9f1d0726eeb0b41924 503 PRINTS PR01036 Tetracycline resistance protein TetB signature 203 221 2.0E-8 T 01-11-2018 AFULGI_00025530 b8f02506a7732d9f1d0726eeb0b41924 503 PRINTS PR01036 Tetracycline resistance protein TetB signature 400 419 2.0E-8 T 01-11-2018 AFULGI_00025530 b8f02506a7732d9f1d0726eeb0b41924 503 SUPERFAMILY SSF103473 8 486 1.05E-67 T 01-11-2018 IPR036259 MFS transporter superfamily AFULGI_00025530 b8f02506a7732d9f1d0726eeb0b41924 503 Gene3D G3DSA:1.20.1720.10 16 206 9.1E-45 T 01-11-2018 AFULGI_00001000 351efdb647305edc8ddd38eb0df1b669 189 Gene3D G3DSA:3.40.1380.20 1 189 4.8E-89 T 01-11-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AFULGI_00001000 351efdb647305edc8ddd38eb0df1b669 189 Pfam PF02887 Pyruvate kinase, alpha/beta domain 17 165 9.1E-16 T 01-11-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AFULGI_00001000 351efdb647305edc8ddd38eb0df1b669 189 SUPERFAMILY SSF52935 1 187 8.7E-70 T 01-11-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AFULGI_00001000 351efdb647305edc8ddd38eb0df1b669 189 ProDom PD022619 AF0103 MM1100 MJ0504 UNCHARACTERIZED SIMILAR MA4416 11 186 9.0E-97 T 01-11-2018 IPR015074 Protein of unknown function DUF1867 AFULGI_00001000 351efdb647305edc8ddd38eb0df1b669 189 PIRSF PIRSF016138 1 189 7.6E-95 T 01-11-2018 IPR015074 Protein of unknown function DUF1867 AFULGI_00025700 1f17b54e0504c2b1a60852863b8b73c5 658 Gene3D G3DSA:3.40.50.720 2 191 2.1E-73 T 01-11-2018 AFULGI_00025700 1f17b54e0504c2b1a60852863b8b73c5 658 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 190 284 3.3E-31 T 01-11-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 AFULGI_00025700 1f17b54e0504c2b1a60852863b8b73c5 658 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 310 377 2.7E-12 T 01-11-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 AFULGI_00025700 1f17b54e0504c2b1a60852863b8b73c5 658 Gene3D G3DSA:1.10.12.10 599 657 3.7E-19 T 01-11-2018 IPR014748 Enoyl-CoA hydratase, C-terminal AFULGI_00025700 1f17b54e0504c2b1a60852863b8b73c5 658 Gene3D G3DSA:1.10.1040.10 192 301 4.3E-32 T 01-11-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AFULGI_00025700 1f17b54e0504c2b1a60852863b8b73c5 658 SUPERFAMILY SSF52096 398 658 3.73E-86 T 01-11-2018 IPR029045 ClpP/crotonase-like domain superfamily AFULGI_00025700 1f17b54e0504c2b1a60852863b8b73c5 658 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 498 518 - T 01-11-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 AFULGI_00025700 1f17b54e0504c2b1a60852863b8b73c5 658 SUPERFAMILY SSF48179 189 302 6.38E-31 T 01-11-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AFULGI_00025700 1f17b54e0504c2b1a60852863b8b73c5 658 SUPERFAMILY SSF51735 6 186 5.59E-62 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily AFULGI_00025700 1f17b54e0504c2b1a60852863b8b73c5 658 Gene3D G3DSA:1.10.1040.10 302 388 8.9E-36 T 01-11-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AFULGI_00025700 1f17b54e0504c2b1a60852863b8b73c5 658 Gene3D G3DSA:3.90.226.10 389 598 4.9E-73 T 01-11-2018 AFULGI_00025700 1f17b54e0504c2b1a60852863b8b73c5 658 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 9 187 2.2E-68 T 01-11-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 AFULGI_00025700 1f17b54e0504c2b1a60852863b8b73c5 658 SUPERFAMILY SSF48179 307 377 1.02E-13 T 01-11-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AFULGI_00025700 1f17b54e0504c2b1a60852863b8b73c5 658 Pfam PF00378 Enoyl-CoA hydratase/isomerase 409 657 4.3E-60 T 01-11-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 AFULGI_00011050 491726064a606265660af72dd5cefd9b 247 SUPERFAMILY SSF46785 2 98 1.63E-10 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00011050 491726064a606265660af72dd5cefd9b 247 Gene3D G3DSA:1.10.10.10 1 101 2.4E-27 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00011050 491726064a606265660af72dd5cefd9b 247 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 8 74 6.3E-26 T 01-11-2018 IPR002831 Transcription regulator TrmB, N-terminal AFULGI_00007030 64e00fc5920fec6f86328161f27b6bb2 556 SUPERFAMILY SSF56091 221 420 9.59E-55 T 01-11-2018 AFULGI_00007030 64e00fc5920fec6f86328161f27b6bb2 556 TIGRFAM TIGR00574 dnl1: DNA ligase I, ATP-dependent (dnl1) 59 548 2.5E-142 T 01-11-2018 IPR000977 DNA ligase, ATP-dependent GO:0003910|GO:0005524|GO:0006281|GO:0006310|GO:0071897 AFULGI_00007030 64e00fc5920fec6f86328161f27b6bb2 556 ProSitePatterns PS00697 ATP-dependent DNA ligase AMP-binding site. 248 256 - T 01-11-2018 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 AFULGI_00007030 64e00fc5920fec6f86328161f27b6bb2 556 ProSitePatterns PS00333 ATP-dependent DNA ligase signature 2. 396 420 - T 01-11-2018 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 AFULGI_00007030 64e00fc5920fec6f86328161f27b6bb2 556 Gene3D G3DSA:3.30.470.30 223 419 4.3E-77 T 01-11-2018 AFULGI_00007030 64e00fc5920fec6f86328161f27b6bb2 556 Gene3D G3DSA:2.40.50.140 420 556 1.1E-51 T 01-11-2018 AFULGI_00007030 64e00fc5920fec6f86328161f27b6bb2 556 Pfam PF04679 ATP dependent DNA ligase C terminal region 440 532 8.7E-21 T 01-11-2018 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 AFULGI_00007030 64e00fc5920fec6f86328161f27b6bb2 556 Hamap MF_00407 DNA ligase [lig]. 2 548 33.328 T 01-11-2018 IPR022865 DNA ligase, ATP-dependent, bacterial/archaeal GO:0003910 AFULGI_00007030 64e00fc5920fec6f86328161f27b6bb2 556 SUPERFAMILY SSF50249 423 550 8.4E-39 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold AFULGI_00007030 64e00fc5920fec6f86328161f27b6bb2 556 SUPERFAMILY SSF117018 2 243 1.22E-68 T 01-11-2018 IPR036599 DNA ligase, ATP-dependent, N-terminal domain superfamily GO:0003677|GO:0003910|GO:0006281|GO:0006310 AFULGI_00007030 64e00fc5920fec6f86328161f27b6bb2 556 Pfam PF01068 ATP dependent DNA ligase domain 227 420 5.4E-63 T 01-11-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 AFULGI_00007030 64e00fc5920fec6f86328161f27b6bb2 556 Gene3D G3DSA:1.10.3260.10 1 222 1.1E-80 T 01-11-2018 IPR036599 DNA ligase, ATP-dependent, N-terminal domain superfamily GO:0003677|GO:0003910|GO:0006281|GO:0006310 AFULGI_00007030 64e00fc5920fec6f86328161f27b6bb2 556 Pfam PF04675 DNA ligase N terminus 4 178 1.4E-38 T 01-11-2018 IPR012308 DNA ligase, ATP-dependent, N-terminal GO:0003677|GO:0003910|GO:0006281|GO:0006310 AFULGI_00020440 310bdac997ef4d3d264294b2ec017fbf 70 SMART SM00530 4 59 1.4E-17 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFULGI_00020440 310bdac997ef4d3d264294b2ec017fbf 70 Gene3D G3DSA:1.10.260.40 1 65 1.4E-27 T 01-11-2018 AFULGI_00020440 310bdac997ef4d3d264294b2ec017fbf 70 Pfam PF01381 Helix-turn-helix 5 59 3.7E-17 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFULGI_00020440 310bdac997ef4d3d264294b2ec017fbf 70 SUPERFAMILY SSF47413 3 64 1.05E-19 T 01-11-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFULGI_00011280 5c82e9c8d704b0f57c4c29ae0abb1e89 886 SUPERFAMILY SSF75712 390 487 9.81E-18 T 01-11-2018 AFULGI_00011280 5c82e9c8d704b0f57c4c29ae0abb1e89 886 Gene3D G3DSA:3.40.50.300 2 226 5.5E-40 T 01-11-2018 AFULGI_00011280 5c82e9c8d704b0f57c4c29ae0abb1e89 886 Gene3D G3DSA:1.10.287.510 388 499 8.3E-24 T 01-11-2018 AFULGI_00011280 5c82e9c8d704b0f57c4c29ae0abb1e89 886 Pfam PF04423 Rad50 zinc hook motif 417 467 3.0E-15 T 01-11-2018 IPR013134 RAD50, zinc hook Reactome: R-HSA-2559586|Reactome: R-HSA-5685938|Reactome: R-HSA-5685939|Reactome: R-HSA-5685942|Reactome: R-HSA-5693548|Reactome: R-HSA-5693554|Reactome: R-HSA-5693565|Reactome: R-HSA-5693568|Reactome: R-HSA-5693571|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 AFULGI_00011280 5c82e9c8d704b0f57c4c29ae0abb1e89 886 SUPERFAMILY SSF52540 4 303 7.97E-18 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00011280 5c82e9c8d704b0f57c4c29ae0abb1e89 886 SUPERFAMILY SSF52540 5 876 2.52E-28 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00011280 5c82e9c8d704b0f57c4c29ae0abb1e89 886 Gene3D G3DSA:3.40.50.300 663 884 1.1E-38 T 01-11-2018 AFULGI_00011280 5c82e9c8d704b0f57c4c29ae0abb1e89 886 Hamap MF_00449 DNA double-strand break repair Rad50 ATPase [rad50]. 2 882 13.475 T 01-11-2018 IPR022982 DNA double-strand break repair Rad50 ATPase, archaeal type AFULGI_00011280 5c82e9c8d704b0f57c4c29ae0abb1e89 886 Pfam PF13175 AAA ATPase domain 4 378 4.9E-15 T 01-11-2018 AFULGI_00006560 72653590310dec62ff8eadedf3205cc2 257 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 2 255 1.6E-88 T 01-11-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 AFULGI_00006560 72653590310dec62ff8eadedf3205cc2 257 Gene3D G3DSA:3.60.10.10 1 257 2.7E-80 T 01-11-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily AFULGI_00006560 72653590310dec62ff8eadedf3205cc2 257 ProSitePatterns PS00726 AP endonucleases family 1 signature 1. 28 37 - T 01-11-2018 IPR020847 AP endonuclease 1, binding site GO:0003677|GO:0004519|GO:0005622|GO:0006281 AFULGI_00006560 72653590310dec62ff8eadedf3205cc2 257 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 5 248 8.5E-17 T 01-11-2018 IPR005135 Endonuclease/exonuclease/phosphatase AFULGI_00006560 72653590310dec62ff8eadedf3205cc2 257 SUPERFAMILY SSF56219 2 256 6.94E-72 T 01-11-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily AFULGI_00006560 72653590310dec62ff8eadedf3205cc2 257 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 2 255 4.5E-108 T 01-11-2018 AFULGI_00025440 0ad90a9ecc66fe7a36bc47aabef0077d 403 ProSitePatterns PS00483 Dihydroorotase signature 2. 275 286 - T 01-11-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFULGI_00025440 0ad90a9ecc66fe7a36bc47aabef0077d 403 ProSitePatterns PS00482 Dihydroorotase signature 1. 46 54 - T 01-11-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFULGI_00025440 0ad90a9ecc66fe7a36bc47aabef0077d 403 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 10 391 1.3E-138 T 01-11-2018 AFULGI_00025440 0ad90a9ecc66fe7a36bc47aabef0077d 403 Pfam PF01979 Amidohydrolase family 39 386 1.2E-16 T 01-11-2018 IPR006680 Amidohydrolase-related GO:0016787 AFULGI_00025440 0ad90a9ecc66fe7a36bc47aabef0077d 403 SUPERFAMILY SSF51556 44 334 9.19E-65 T 01-11-2018 IPR032466 Metal-dependent hydrolase AFULGI_00025440 0ad90a9ecc66fe7a36bc47aabef0077d 403 SUPERFAMILY SSF51338 4 392 5.45E-14 T 01-11-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 AFULGI_00025440 0ad90a9ecc66fe7a36bc47aabef0077d 403 Hamap MF_00220_A Dihydroorotase [pyrC]. 1 396 64.816 T 01-11-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFULGI_00025440 0ad90a9ecc66fe7a36bc47aabef0077d 403 Gene3D G3DSA:3.20.20.140 34 402 8.7E-88 T 01-11-2018 AFULGI_00002600 e516bb5f0cfa569e0935eb81a29dc81a 597 Gene3D G3DSA:3.60.60.10 153 434 1.1E-25 T 01-11-2018 AFULGI_00002600 e516bb5f0cfa569e0935eb81a29dc81a 597 Pfam PF03417 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase 176 370 5.7E-6 T 01-11-2018 IPR005079 Peptidase C45 AFULGI_00005450 ce9db230c11430a1d4c76431e767d7c2 61 SUPERFAMILY SSF103456 3 57 9.68E-15 T 01-11-2018 IPR023391 Protein translocase SecE domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 AFULGI_00005450 ce9db230c11430a1d4c76431e767d7c2 61 Hamap MF_00422 Protein translocase subunit SecE [secE]. 4 59 11.987 T 01-11-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 AFULGI_00005450 ce9db230c11430a1d4c76431e767d7c2 61 Gene3D G3DSA:1.20.5.820 1 61 8.9E-17 T 01-11-2018 IPR023391 Protein translocase SecE domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 AFULGI_00005450 ce9db230c11430a1d4c76431e767d7c2 61 TIGRFAM TIGR00327 secE_euk_arch: protein translocase SEC61 complex gamma subunit, archaeal and eukaryotic 1 61 6.2E-32 T 01-11-2018 IPR008158 Protein translocase SEC61 complex, gamma subunit GO:0015031|GO:0015450|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 AFULGI_00006680 8a4a965c593b55f6ebab6cb744aef99f 128 SUPERFAMILY SSF81593 10 124 5.89E-32 T 01-11-2018 AFULGI_00006680 8a4a965c593b55f6ebab6cb744aef99f 128 Gene3D G3DSA:1.20.120.330 3 125 5.9E-30 T 01-11-2018 AFULGI_00006680 8a4a965c593b55f6ebab6cb744aef99f 128 Pfam PF05168 HEPN domain 7 122 4.1E-34 T 01-11-2018 IPR007842 HEPN domain AFULGI_00006680 8a4a965c593b55f6ebab6cb744aef99f 128 SMART SM00748 11 116 8.4E-40 T 01-11-2018 IPR007842 HEPN domain AFULGI_00022610 45902556eabc39f6c299aa58be392d66 73 Pfam PF02697 Putative antitoxin 3 67 1.2E-22 T 01-11-2018 IPR003847 Putative antitoxin AFULGI_00022610 45902556eabc39f6c299aa58be392d66 73 ProDom PD188822 UPF0330 AF1997 ST1125.1 AF1689 AF1478 C1_0043 PYRAB04040 PF1222 MM2475 MA1514 3 53 7.0E-22 T 01-11-2018 IPR003847 Putative antitoxin AFULGI_00022610 45902556eabc39f6c299aa58be392d66 73 Hamap MF_00794 Putative antitoxin . 2 70 17.617 T 01-11-2018 IPR003847 Putative antitoxin AFULGI_00023660 43f56720fc5529c3666c8d701b7488eb 811 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 571 701 4.2E-47 T 01-11-2018 IPR003959 ATPase, AAA-type, core GO:0005524 AFULGI_00023660 43f56720fc5529c3666c8d701b7488eb 811 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 234 363 1.3E-50 T 01-11-2018 IPR003959 ATPase, AAA-type, core GO:0005524 AFULGI_00023660 43f56720fc5529c3666c8d701b7488eb 811 Gene3D G3DSA:1.10.8.60 441 524 9.6E-20 T 01-11-2018 AFULGI_00023660 43f56720fc5529c3666c8d701b7488eb 811 Pfam PF02359 Cell division protein 48 (CDC48), N-terminal domain 8 91 5.3E-32 T 01-11-2018 IPR003338 CDC48, N-terminal subdomain AFULGI_00023660 43f56720fc5529c3666c8d701b7488eb 811 SUPERFAMILY SSF52540 529 792 8.54E-80 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00023660 43f56720fc5529c3666c8d701b7488eb 811 SUPERFAMILY SSF50692 3 91 4.47E-29 T 01-11-2018 IPR009010 Aspartate decarboxylase-like domain superfamily AFULGI_00023660 43f56720fc5529c3666c8d701b7488eb 811 SMART SM01072 109 185 8.4E-16 T 01-11-2018 IPR004201 CDC48, domain 2 AFULGI_00023660 43f56720fc5529c3666c8d701b7488eb 811 Gene3D G3DSA:1.10.8.60 703 775 3.2E-109 T 01-11-2018 AFULGI_00023660 43f56720fc5529c3666c8d701b7488eb 811 Pfam PF09336 Vps4 C terminal oligomerisation domain 756 792 5.0E-5 T 01-11-2018 IPR015415 Vps4 oligomerisation, C-terminal AFULGI_00023660 43f56720fc5529c3666c8d701b7488eb 811 Gene3D G3DSA:1.10.8.60 365 386 3.5E-79 T 01-11-2018 AFULGI_00023660 43f56720fc5529c3666c8d701b7488eb 811 ProSitePatterns PS00674 AAA-protein family signature. 672 690 - T 01-11-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 AFULGI_00023660 43f56720fc5529c3666c8d701b7488eb 811 SUPERFAMILY SSF54585 93 199 1.5E-19 T 01-11-2018 IPR029067 CDC48 domain 2-like superfamily AFULGI_00023660 43f56720fc5529c3666c8d701b7488eb 811 SMART SM01073 8 92 3.5E-39 T 01-11-2018 IPR003338 CDC48, N-terminal subdomain AFULGI_00023660 43f56720fc5529c3666c8d701b7488eb 811 Gene3D G3DSA:3.10.330.10 93 179 1.8E-7 T 01-11-2018 AFULGI_00023660 43f56720fc5529c3666c8d701b7488eb 811 ProSitePatterns PS00674 AAA-protein family signature. 334 352 - T 01-11-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 AFULGI_00023660 43f56720fc5529c3666c8d701b7488eb 811 SUPERFAMILY SSF52540 194 522 4.8E-70 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00023660 43f56720fc5529c3666c8d701b7488eb 811 SMART SM00382 567 704 1.5E-24 T 01-11-2018 IPR003593 AAA+ ATPase domain AFULGI_00023660 43f56720fc5529c3666c8d701b7488eb 811 SMART SM00382 230 366 4.8E-26 T 01-11-2018 IPR003593 AAA+ ATPase domain AFULGI_00023660 43f56720fc5529c3666c8d701b7488eb 811 TIGRFAM TIGR01243 CDC48: AAA family ATPase, CDC48 subfamily 7 794 0.0 T 01-11-2018 IPR005938 AAA ATPase, CDC48 family GO:0016787 Reactome: R-HSA-110320|Reactome: R-HSA-3371511|Reactome: R-HSA-382556|Reactome: R-HSA-532668|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5678895|Reactome: R-HSA-5689877|Reactome: R-HSA-5689896|Reactome: R-HSA-6798695|Reactome: R-HSA-8866654|Reactome: R-HSA-8876725 AFULGI_00023660 43f56720fc5529c3666c8d701b7488eb 811 Gene3D G3DSA:2.40.40.20 1 92 2.6E-34 T 01-11-2018 AFULGI_00023660 43f56720fc5529c3666c8d701b7488eb 811 Pfam PF02933 Cell division protein 48 (CDC48), domain 2 110 184 9.2E-17 T 01-11-2018 IPR004201 CDC48, domain 2 AFULGI_00023660 43f56720fc5529c3666c8d701b7488eb 811 Gene3D G3DSA:3.40.50.300 194 364 3.5E-79 T 01-11-2018 AFULGI_00023660 43f56720fc5529c3666c8d701b7488eb 811 Gene3D G3DSA:3.40.50.300 529 790 3.2E-109 T 01-11-2018 AFULGI_00000150 21c16800a226472e92a8f0a1ea51c810 641 Gene3D G3DSA:3.90.226.10 399 624 1.5E-77 T 01-11-2018 AFULGI_00000150 21c16800a226472e92a8f0a1ea51c810 641 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 8 25 2.2E-7 T 01-11-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 AFULGI_00000150 21c16800a226472e92a8f0a1ea51c810 641 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 67 94 2.2E-7 T 01-11-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 AFULGI_00000150 21c16800a226472e92a8f0a1ea51c810 641 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 5 184 2.6E-65 T 01-11-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 AFULGI_00000150 21c16800a226472e92a8f0a1ea51c810 641 Pfam PF00378 Enoyl-CoA hydratase/isomerase 409 619 5.7E-57 T 01-11-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 AFULGI_00000150 21c16800a226472e92a8f0a1ea51c810 641 SUPERFAMILY SSF52096 401 621 9.38E-76 T 01-11-2018 IPR029045 ClpP/crotonase-like domain superfamily AFULGI_00000150 21c16800a226472e92a8f0a1ea51c810 641 SUPERFAMILY SSF48179 301 410 6.89E-28 T 01-11-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AFULGI_00000150 21c16800a226472e92a8f0a1ea51c810 641 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 499 519 - T 01-11-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 AFULGI_00000150 21c16800a226472e92a8f0a1ea51c810 641 SUPERFAMILY SSF51735 2 183 1.51E-57 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily AFULGI_00000150 21c16800a226472e92a8f0a1ea51c810 641 Gene3D G3DSA:1.10.1040.10 189 297 1.0E-29 T 01-11-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AFULGI_00000150 21c16800a226472e92a8f0a1ea51c810 641 SUPERFAMILY SSF48179 186 292 3.15E-27 T 01-11-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AFULGI_00000150 21c16800a226472e92a8f0a1ea51c810 641 Gene3D G3DSA:3.40.50.720 1 188 4.7E-69 T 01-11-2018 AFULGI_00000150 21c16800a226472e92a8f0a1ea51c810 641 Gene3D G3DSA:1.10.1040.10 307 398 1.2E-25 T 01-11-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AFULGI_00000150 21c16800a226472e92a8f0a1ea51c810 641 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 187 285 5.8E-29 T 01-11-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 AFULGI_00000150 21c16800a226472e92a8f0a1ea51c810 641 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 305 397 7.2E-22 T 01-11-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 AFULGI_00009750 02de9718184b7b0ad58b4b204579b9b0 336 Gene3D G3DSA:3.40.50.1480 5 330 5.3E-49 T 01-11-2018 AFULGI_00009750 02de9718184b7b0ad58b4b204579b9b0 336 SMART SM00996 2 336 2.0E-4 T 01-11-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 AFULGI_00009750 02de9718184b7b0ad58b4b204579b9b0 336 SMART SM00997 141 289 4.3E-38 T 01-11-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 AFULGI_00009750 02de9718184b7b0ad58b4b204579b9b0 336 SUPERFAMILY SSF52283 25 327 2.72E-9 T 01-11-2018 AFULGI_00009750 02de9718184b7b0ad58b4b204579b9b0 336 Gene3D G3DSA:3.40.50.720 143 289 5.3E-49 T 01-11-2018 AFULGI_00009750 02de9718184b7b0ad58b4b204579b9b0 336 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 162 178 - T 01-11-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 AFULGI_00009750 02de9718184b7b0ad58b4b204579b9b0 336 SUPERFAMILY SSF51735 141 289 2.26E-23 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily AFULGI_00009750 02de9718184b7b0ad58b4b204579b9b0 336 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 143 251 1.9E-18 T 01-11-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 AFULGI_00010700 561b4f02db0f8b57939ba8d239bddc79 218 SUPERFAMILY SSF161098 19 200 2.35E-34 T 01-11-2018 IPR035906 MetI-like superfamily AFULGI_00010700 561b4f02db0f8b57939ba8d239bddc79 218 Gene3D G3DSA:1.10.3720.10 15 211 1.7E-28 T 01-11-2018 IPR035906 MetI-like superfamily AFULGI_00010700 561b4f02db0f8b57939ba8d239bddc79 218 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 38 214 2.2E-24 T 01-11-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFULGI_00017940 40ca69857bf1b148b37001dc1b1e8c29 382 Pfam PF08442 ATP-grasp domain 2 194 1.1E-75 T 01-11-2018 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 AFULGI_00017940 40ca69857bf1b148b37001dc1b1e8c29 382 Pfam PF00549 CoA-ligase 254 356 3.1E-16 T 01-11-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AFULGI_00017940 40ca69857bf1b148b37001dc1b1e8c29 382 SUPERFAMILY SSF52210 230 380 1.83E-42 T 01-11-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AFULGI_00017940 40ca69857bf1b148b37001dc1b1e8c29 382 PIRSF PIRSF001554 1 382 4.7E-142 T 01-11-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 AFULGI_00017940 40ca69857bf1b148b37001dc1b1e8c29 382 Gene3D G3DSA:3.30.1490.20 21 96 6.2E-85 T 01-11-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 AFULGI_00017940 40ca69857bf1b148b37001dc1b1e8c29 382 Hamap MF_00558 Succinate--CoA ligase [ADP-forming] subunit beta [sucC]. 1 382 39.468 T 01-11-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 AFULGI_00017940 40ca69857bf1b148b37001dc1b1e8c29 382 Gene3D G3DSA:3.30.470.20 1 225 6.2E-85 T 01-11-2018 AFULGI_00017940 40ca69857bf1b148b37001dc1b1e8c29 382 SUPERFAMILY SSF56059 1 229 1.94E-73 T 01-11-2018 AFULGI_00017940 40ca69857bf1b148b37001dc1b1e8c29 382 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 1 381 2.4E-143 T 01-11-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 AFULGI_00017940 40ca69857bf1b148b37001dc1b1e8c29 382 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 248 273 - T 01-11-2018 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AFULGI_00017940 40ca69857bf1b148b37001dc1b1e8c29 382 Gene3D G3DSA:3.40.50.261 231 382 4.6E-46 T 01-11-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AFULGI_00024730 e2432a6f0459eeed58f2ad5565091d2d 184 Pfam PF09918 Uncharacterized protein containing a ferredoxin domain (DUF2148) 115 180 5.1E-32 T 01-11-2018 IPR019224 Protein of unknown function DUF2148 AFULGI_00024730 e2432a6f0459eeed58f2ad5565091d2d 184 Gene3D G3DSA:3.40.109.10 6 168 5.0E-6 T 01-11-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 AFULGI_00009390 e58ec64bf7cc9f9b1608527191f9c1e6 294 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 146 291 2.3E-21 T 01-11-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 AFULGI_00009390 e58ec64bf7cc9f9b1608527191f9c1e6 294 ProSitePatterns PS00064 L-lactate dehydrogenase active site. 169 175 - T 01-11-2018 IPR018177 L-lactate dehydrogenase, active site GO:0004459|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 AFULGI_00009390 e58ec64bf7cc9f9b1608527191f9c1e6 294 PIRSF PIRSF000102 1 294 3.8E-94 T 01-11-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 AFULGI_00009390 e58ec64bf7cc9f9b1608527191f9c1e6 294 Gene3D G3DSA:3.40.50.720 1 142 2.9E-56 T 01-11-2018 AFULGI_00009390 e58ec64bf7cc9f9b1608527191f9c1e6 294 PRINTS PR00086 L-lactate dehydrogenase signature 2 26 5.0E-33 T 01-11-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 AFULGI_00009390 e58ec64bf7cc9f9b1608527191f9c1e6 294 PRINTS PR00086 L-lactate dehydrogenase signature 115 135 5.0E-33 T 01-11-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 AFULGI_00009390 e58ec64bf7cc9f9b1608527191f9c1e6 294 PRINTS PR00086 L-lactate dehydrogenase signature 27 51 5.0E-33 T 01-11-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 AFULGI_00009390 e58ec64bf7cc9f9b1608527191f9c1e6 294 PRINTS PR00086 L-lactate dehydrogenase signature 167 180 5.0E-33 T 01-11-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 AFULGI_00009390 e58ec64bf7cc9f9b1608527191f9c1e6 294 PRINTS PR00086 L-lactate dehydrogenase signature 139 157 5.0E-33 T 01-11-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 AFULGI_00009390 e58ec64bf7cc9f9b1608527191f9c1e6 294 SUPERFAMILY SSF56327 143 292 1.31E-40 T 01-11-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 AFULGI_00009390 e58ec64bf7cc9f9b1608527191f9c1e6 294 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 2 141 3.3E-40 T 01-11-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 AFULGI_00009390 e58ec64bf7cc9f9b1608527191f9c1e6 294 Gene3D G3DSA:3.90.110.10 143 294 1.7E-43 T 01-11-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 AFULGI_00009390 e58ec64bf7cc9f9b1608527191f9c1e6 294 SUPERFAMILY SSF51735 1 142 2.79E-46 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily AFULGI_00022370 a9b91931c8604d1f77f2e8b38ce5fb7f 156 TIGRFAM TIGR00270 TIGR00270: TIGR00270 family protein 1 153 5.8E-69 T 01-11-2018 IPR004451 Conserved hypothetical protein CHP00270 AFULGI_00022370 a9b91931c8604d1f77f2e8b38ce5fb7f 156 SMART SM00530 74 129 5.3E-13 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFULGI_00022370 a9b91931c8604d1f77f2e8b38ce5fb7f 156 Pfam PF01381 Helix-turn-helix 75 128 7.6E-14 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFULGI_00022370 a9b91931c8604d1f77f2e8b38ce5fb7f 156 Gene3D G3DSA:1.10.260.40 62 156 1.7E-18 T 01-11-2018 AFULGI_00022370 a9b91931c8604d1f77f2e8b38ce5fb7f 156 SUPERFAMILY SSF47413 69 130 9.85E-13 T 01-11-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFULGI_00012670 465c31a91dd1e6135db626b95128e5ec 209 Hamap MF_00271 V-type ATP synthase subunit D [atpD]. 1 209 25.528 T 01-11-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 AFULGI_00012670 465c31a91dd1e6135db626b95128e5ec 209 TIGRFAM TIGR00309 V_ATPase_subD: V-type ATPase, D subunit 1 208 2.4E-94 T 01-11-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 AFULGI_00012670 465c31a91dd1e6135db626b95128e5ec 209 Pfam PF01813 ATP synthase subunit D 10 203 9.7E-58 T 01-11-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 AFULGI_00021800 fb937697c8fa3b532e860339c349ff68 133 ProSitePatterns PS00323 Ribosomal protein S19 signature. 86 110 - T 01-11-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00021800 fb937697c8fa3b532e860339c349ff68 133 SUPERFAMILY SSF54570 52 117 3.53E-25 T 01-11-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00021800 fb937697c8fa3b532e860339c349ff68 133 Gene3D G3DSA:3.30.860.20 2 133 3.2E-49 T 01-11-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00021800 fb937697c8fa3b532e860339c349ff68 133 PRINTS PR00975 Ribosomal protein S19 family signature 66 85 1.8E-17 T 01-11-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00021800 fb937697c8fa3b532e860339c349ff68 133 PRINTS PR00975 Ribosomal protein S19 family signature 86 98 1.8E-17 T 01-11-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00021800 fb937697c8fa3b532e860339c349ff68 133 PRINTS PR00975 Ribosomal protein S19 family signature 98 113 1.8E-17 T 01-11-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00021800 fb937697c8fa3b532e860339c349ff68 133 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 39 122 23.47 T 01-11-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00021800 fb937697c8fa3b532e860339c349ff68 133 Pfam PF00203 Ribosomal protein S19 41 116 1.4E-28 T 01-11-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00021800 fb937697c8fa3b532e860339c349ff68 133 TIGRFAM TIGR01025 uS19_arch: ribosomal protein uS19 10 133 8.7E-64 T 01-11-2018 IPR005713 Ribosomal protein S19A/S15e GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00021800 fb937697c8fa3b532e860339c349ff68 133 PIRSF PIRSF002144 1 133 2.1E-37 T 01-11-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00007710 2db76845f0c7450a55039d1d7be51551 252 Pfam PF00850 Histone deacetylase domain 68 134 1.1E-9 T 01-11-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 AFULGI_00007710 2db76845f0c7450a55039d1d7be51551 252 SUPERFAMILY SSF52768 4 227 2.88E-20 T 01-11-2018 IPR023696 Ureohydrolase domain superfamily AFULGI_00007710 2db76845f0c7450a55039d1d7be51551 252 PRINTS PR01270 Histone deacetylase superfamily signature 122 137 5.9E-8 T 01-11-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 AFULGI_00007710 2db76845f0c7450a55039d1d7be51551 252 PRINTS PR01270 Histone deacetylase superfamily signature 91 114 5.9E-8 T 01-11-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 AFULGI_00007710 2db76845f0c7450a55039d1d7be51551 252 PRINTS PR01270 Histone deacetylase superfamily signature 187 197 5.9E-8 T 01-11-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 AFULGI_00007710 2db76845f0c7450a55039d1d7be51551 252 Gene3D G3DSA:3.40.800.20 18 247 1.4E-15 T 01-11-2018 IPR037138 Histone deacetylase domain superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 AFULGI_00012750 39869aede6ee693df5927be2d685b0db 248 SUPERFAMILY SSF160104 5 248 7.19E-40 T 01-11-2018 IPR023375 Acetoacetate decarboxylase domain superfamily KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 AFULGI_00012750 39869aede6ee693df5927be2d685b0db 248 Gene3D G3DSA:2.40.400.10 6 248 4.8E-45 T 01-11-2018 IPR023375 Acetoacetate decarboxylase domain superfamily KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 AFULGI_00012750 39869aede6ee693df5927be2d685b0db 248 Pfam PF06314 Acetoacetate decarboxylase (ADC) 15 248 3.1E-51 T 01-11-2018 IPR010451 Acetoacetate decarboxylase GO:0016829 KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 AFULGI_00013040 641a110b2f2da12961d8110a916b4047 486 Pfam PF00474 Sodium:solute symporter family 37 416 2.8E-28 T 01-11-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 AFULGI_00013040 641a110b2f2da12961d8110a916b4047 486 Gene3D G3DSA:1.20.1730.10 25 477 1.7E-63 T 01-11-2018 IPR038377 Sodium/glucose symporter superfamily AFULGI_00024330 8b063bb040f21941297fe0cb3fc3991f 175 Pfam PF06863 Protein of unknown function (DUF1254) 43 168 3.2E-23 T 01-11-2018 IPR010679 Domain of unknown function DUF1254 AFULGI_00024330 8b063bb040f21941297fe0cb3fc3991f 175 SUPERFAMILY SSF160935 13 172 4.32E-25 T 01-11-2018 AFULGI_00024330 8b063bb040f21941297fe0cb3fc3991f 175 PIRSF PIRSF010244 1 172 3.7E-72 T 01-11-2018 IPR014456 Uncharacterised conserved protein UCP010244, integral membrane protein AFULGI_00024200 1e57bf4555adc299ad00d88fa3855baf 156 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 5 134 5.1E-53 T 01-11-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AFULGI_00024200 1e57bf4555adc299ad00d88fa3855baf 156 Gene3D G3DSA:3.30.70.640 1 156 1.2E-62 T 01-11-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AFULGI_00024200 1e57bf4555adc299ad00d88fa3855baf 156 Pfam PF01967 MoaC family 13 153 5.7E-51 T 01-11-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AFULGI_00024200 1e57bf4555adc299ad00d88fa3855baf 156 Hamap MF_01224_A Cyclic pyranopterin monophosphate synthase [moaC]. 8 153 39.13 T 01-11-2018 IPR023047 Probable cyclic pyranopterin monophosphate synthase accessory protein, archaea KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823 AFULGI_00024200 1e57bf4555adc299ad00d88fa3855baf 156 SUPERFAMILY SSF55040 9 154 3.01E-50 T 01-11-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AFULGI_00025890 3ca4bc560b58eb8c88b762b797624823 243 Gene3D G3DSA:3.40.800.20 164 243 1.6E-13 T 01-11-2018 IPR037138 Histone deacetylase domain superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 AFULGI_00025890 3ca4bc560b58eb8c88b762b797624823 243 Pfam PF00850 Histone deacetylase domain 62 154 1.1E-24 T 01-11-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 AFULGI_00025890 3ca4bc560b58eb8c88b762b797624823 243 Pfam PF00850 Histone deacetylase domain 166 240 4.8E-9 T 01-11-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 AFULGI_00025890 3ca4bc560b58eb8c88b762b797624823 243 SUPERFAMILY SSF52768 1 242 4.8E-53 T 01-11-2018 IPR023696 Ureohydrolase domain superfamily AFULGI_00025890 3ca4bc560b58eb8c88b762b797624823 243 PRINTS PR01270 Histone deacetylase superfamily signature 94 117 1.9E-13 T 01-11-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 AFULGI_00025890 3ca4bc560b58eb8c88b762b797624823 243 PRINTS PR01270 Histone deacetylase superfamily signature 128 143 1.9E-13 T 01-11-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 AFULGI_00025890 3ca4bc560b58eb8c88b762b797624823 243 PRINTS PR01270 Histone deacetylase superfamily signature 174 184 1.9E-13 T 01-11-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 AFULGI_00025890 3ca4bc560b58eb8c88b762b797624823 243 Gene3D G3DSA:3.40.800.20 6 163 1.2E-37 T 01-11-2018 IPR037138 Histone deacetylase domain superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 AFULGI_00023640 6a967b48cc7fd64b8888807d2f8bfca3 218 Pfam PF08423 Rad51 3 217 1.6E-29 T 01-11-2018 IPR013632 DNA recombination and repair protein Rad51-like, C-terminal Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579 AFULGI_00023640 6a967b48cc7fd64b8888807d2f8bfca3 218 SMART SM00382 20 188 6.4E-10 T 01-11-2018 IPR003593 AAA+ ATPase domain AFULGI_00023640 6a967b48cc7fd64b8888807d2f8bfca3 218 Gene3D G3DSA:3.40.50.300 1 218 3.8E-50 T 01-11-2018 AFULGI_00023640 6a967b48cc7fd64b8888807d2f8bfca3 218 PIRSF PIRSF003336 1 218 1.4E-94 T 01-11-2018 IPR011939 DNA repair and recombination protein RadB GO:0003684|GO:0005524|GO:0006281|GO:0006310 AFULGI_00023640 6a967b48cc7fd64b8888807d2f8bfca3 218 TIGRFAM TIGR02237 recomb_radB: DNA repair and recombination protein RadB 10 217 8.0E-90 T 01-11-2018 IPR011939 DNA repair and recombination protein RadB GO:0003684|GO:0005524|GO:0006281|GO:0006310 AFULGI_00023640 6a967b48cc7fd64b8888807d2f8bfca3 218 SUPERFAMILY SSF52540 3 217 1.76E-40 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00023640 6a967b48cc7fd64b8888807d2f8bfca3 218 Hamap MF_00350 DNA repair and recombination protein RadB [radB]. 9 217 37.729 T 01-11-2018 IPR011939 DNA repair and recombination protein RadB GO:0003684|GO:0005524|GO:0006281|GO:0006310 AFULGI_00023640 6a967b48cc7fd64b8888807d2f8bfca3 218 PRINTS PR01874 DNA repair protein radA signature 12 40 4.3E-7 T 01-11-2018 AFULGI_00023640 6a967b48cc7fd64b8888807d2f8bfca3 218 PRINTS PR01874 DNA repair protein radA signature 190 216 4.3E-7 T 01-11-2018 AFULGI_00004540 770cb818a97b91ee3b104b33412461c3 771 Gene3D G3DSA:3.30.450.20 419 546 1.3E-18 T 01-11-2018 AFULGI_00004540 770cb818a97b91ee3b104b33412461c3 771 SMART SM00388 699 757 8.4E-6 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFULGI_00004540 770cb818a97b91ee3b104b33412461c3 771 SUPERFAMILY SSF55781 122 288 6.54E-25 T 01-11-2018 AFULGI_00004540 770cb818a97b91ee3b104b33412461c3 771 Pfam PF13426 PAS domain 432 533 2.8E-11 T 01-11-2018 IPR000014 PAS domain AFULGI_00004540 770cb818a97b91ee3b104b33412461c3 771 SUPERFAMILY SSF55781 546 702 9.16E-10 T 01-11-2018 AFULGI_00004540 770cb818a97b91ee3b104b33412461c3 771 Gene3D G3DSA:3.30.450.20 286 418 2.2E-24 T 01-11-2018 AFULGI_00004540 770cb818a97b91ee3b104b33412461c3 771 SMART SM00091 421 489 2.1E-12 T 01-11-2018 IPR000014 PAS domain AFULGI_00004540 770cb818a97b91ee3b104b33412461c3 771 SMART SM00091 298 363 5.6E-12 T 01-11-2018 IPR000014 PAS domain AFULGI_00004540 770cb818a97b91ee3b104b33412461c3 771 SMART SM00065 143 294 1.6E-6 T 01-11-2018 IPR003018 GAF domain GO:0005515 AFULGI_00004540 770cb818a97b91ee3b104b33412461c3 771 SMART SM00065 563 691 5.4E-4 T 01-11-2018 IPR003018 GAF domain GO:0005515 AFULGI_00004540 770cb818a97b91ee3b104b33412461c3 771 Pfam PF00989 PAS fold 299 393 7.2E-14 T 01-11-2018 IPR013767 PAS fold GO:0006355 AFULGI_00004540 770cb818a97b91ee3b104b33412461c3 771 SUPERFAMILY SSF55785 315 418 2.09E-19 T 01-11-2018 IPR035965 PAS domain superfamily AFULGI_00004540 770cb818a97b91ee3b104b33412461c3 771 Gene3D G3DSA:3.30.450.40 128 285 2.8E-30 T 01-11-2018 IPR029016 GAF-like domain superfamily AFULGI_00004540 770cb818a97b91ee3b104b33412461c3 771 Gene3D G3DSA:3.30.450.40 547 691 1.2E-9 T 01-11-2018 IPR029016 GAF-like domain superfamily AFULGI_00004540 770cb818a97b91ee3b104b33412461c3 771 Pfam PF13185 GAF domain 141 285 5.5E-22 T 01-11-2018 IPR003018 GAF domain GO:0005515 AFULGI_00004540 770cb818a97b91ee3b104b33412461c3 771 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 297 416 4.0E-25 T 01-11-2018 IPR000014 PAS domain AFULGI_00004540 770cb818a97b91ee3b104b33412461c3 771 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 417 541 2.4E-19 T 01-11-2018 IPR000014 PAS domain AFULGI_00004540 770cb818a97b91ee3b104b33412461c3 771 SUPERFAMILY SSF55785 405 491 1.33E-20 T 01-11-2018 IPR035965 PAS domain superfamily AFULGI_00023360 3a5e0ff68808b71ccbb7a37db2d083a2 108 PIRSF PIRSF015730 1 108 1.1E-32 T 01-11-2018 IPR002836 PDCD5-like GO:0003677 AFULGI_00023360 3a5e0ff68808b71ccbb7a37db2d083a2 108 SUPERFAMILY SSF46950 7 107 8.76E-28 T 01-11-2018 IPR036883 PDCD5-like superfamily GO:0003677 AFULGI_00023360 3a5e0ff68808b71ccbb7a37db2d083a2 108 Hamap MF_00026 DNA-binding protein . 2 107 16.795 T 01-11-2018 IPR022889 DNA-binding protein, archaeal AFULGI_00023360 3a5e0ff68808b71ccbb7a37db2d083a2 108 Pfam PF01984 Double-stranded DNA-binding domain 7 106 2.0E-26 T 01-11-2018 IPR002836 PDCD5-like GO:0003677 AFULGI_00023360 3a5e0ff68808b71ccbb7a37db2d083a2 108 Gene3D G3DSA:1.10.8.140 29 108 1.2E-27 T 01-11-2018 IPR036883 PDCD5-like superfamily GO:0003677 AFULGI_00001840 335fdde3f7a617f3ee15d52c94a958fb 410 SUPERFAMILY SSF47203 235 406 8.38E-43 T 01-11-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 AFULGI_00001840 335fdde3f7a617f3ee15d52c94a958fb 410 Gene3D G3DSA:1.20.140.10 240 404 2.0E-38 T 01-11-2018 AFULGI_00001840 335fdde3f7a617f3ee15d52c94a958fb 410 PIRSF PIRSF016578 4 110 2.4E-6 T 01-11-2018 AFULGI_00001840 335fdde3f7a617f3ee15d52c94a958fb 410 PIRSF PIRSF016578 243 409 2.2E-11 T 01-11-2018 AFULGI_00001840 335fdde3f7a617f3ee15d52c94a958fb 410 PIRSF PIRSF016578 139 202 0.049 T 01-11-2018 AFULGI_00001840 335fdde3f7a617f3ee15d52c94a958fb 410 Gene3D G3DSA:2.40.110.10 123 239 1.1E-28 T 01-11-2018 AFULGI_00001840 335fdde3f7a617f3ee15d52c94a958fb 410 SUPERFAMILY SSF56645 2 247 4.32E-65 T 01-11-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 AFULGI_00001840 335fdde3f7a617f3ee15d52c94a958fb 410 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 124 221 1.7E-20 T 01-11-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 AFULGI_00001840 335fdde3f7a617f3ee15d52c94a958fb 410 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 236 402 6.7E-32 T 01-11-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AFULGI_00001840 335fdde3f7a617f3ee15d52c94a958fb 410 Gene3D G3DSA:1.10.540.10 1 121 2.6E-34 T 01-11-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 AFULGI_00001840 335fdde3f7a617f3ee15d52c94a958fb 410 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 120 3.1E-30 T 01-11-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 AFULGI_00001840 335fdde3f7a617f3ee15d52c94a958fb 410 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 360 379 - T 01-11-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 AFULGI_00008930 0a07cee2e9b7d21790e2ffdede2ec967 461 Gene3D G3DSA:1.10.45.10 417 461 5.3E-13 T 01-11-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 AFULGI_00008930 0a07cee2e9b7d21790e2ffdede2ec967 461 SUPERFAMILY SSF56176 3 212 1.36E-68 T 01-11-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 AFULGI_00008930 0a07cee2e9b7d21790e2ffdede2ec967 461 Pfam PF01565 FAD binding domain 38 174 5.3E-45 T 01-11-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 AFULGI_00008930 0a07cee2e9b7d21790e2ffdede2ec967 461 Pfam PF02913 FAD linked oxidases, C-terminal domain 211 460 2.7E-71 T 01-11-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 AFULGI_00008930 0a07cee2e9b7d21790e2ffdede2ec967 461 Gene3D G3DSA:3.30.70.2740 336 416 3.4E-18 T 01-11-2018 AFULGI_00008930 0a07cee2e9b7d21790e2ffdede2ec967 461 Gene3D G3DSA:3.30.465.40 1 228 6.9E-69 T 01-11-2018 AFULGI_00008930 0a07cee2e9b7d21790e2ffdede2ec967 461 TIGRFAM TIGR00387 glcD: glycolate oxidase, subunit GlcD 40 459 1.5E-179 T 01-11-2018 IPR004490 Glycolate oxidase subunit GlcD GO:0008891|GO:0009339 AFULGI_00008930 0a07cee2e9b7d21790e2ffdede2ec967 461 SUPERFAMILY SSF55103 216 461 1.64E-54 T 01-11-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 AFULGI_00008940 e806e9f7eae618276febc16c7f6a7cc6 95 SUPERFAMILY SSF46548 6 90 1.31E-19 T 01-11-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 AFULGI_00008940 e806e9f7eae618276febc16c7f6a7cc6 95 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 61 72 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFULGI_00008940 e806e9f7eae618276febc16c7f6a7cc6 95 Gene3D G3DSA:1.10.1060.10 1 93 1.9E-9 T 01-11-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 AFULGI_00008940 e806e9f7eae618276febc16c7f6a7cc6 95 Pfam PF13183 4Fe-4S dicluster domain 10 75 4.3E-10 T 01-11-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFULGI_00025830 21db322ddf9606002cecf257aa65af1b 146 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 6 145 24.585 T 01-11-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00025830 21db322ddf9606002cecf257aa65af1b 146 SUPERFAMILY SSF46946 7 141 7.06E-32 T 01-11-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 AFULGI_00025830 21db322ddf9606002cecf257aa65af1b 146 Pfam PF00416 Ribosomal protein S13/S18 8 135 2.3E-41 T 01-11-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00025830 21db322ddf9606002cecf257aa65af1b 146 Gene3D G3DSA:1.10.8.50 1 73 2.6E-23 T 01-11-2018 AFULGI_00025830 21db322ddf9606002cecf257aa65af1b 146 PIRSF PIRSF002134 1 146 8.0E-43 T 01-11-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00025830 21db322ddf9606002cecf257aa65af1b 146 TIGRFAM TIGR03629 uS13_arch: ribosomal protein uS13 3 145 1.9E-63 T 01-11-2018 IPR019977 Ribosomal protein S13, archaeal GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFULGI_00025830 21db322ddf9606002cecf257aa65af1b 146 Gene3D G3DSA:4.10.910.10 85 135 1.3E-18 T 01-11-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00025830 21db322ddf9606002cecf257aa65af1b 146 ProSitePatterns PS00646 Ribosomal protein S13 signature. 114 127 - T 01-11-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00018940 68494e0c8702785f3abeca4ea79f42ee 438 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 308 319 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFULGI_00018940 68494e0c8702785f3abeca4ea79f42ee 438 SUPERFAMILY SSF54862 28 330 2.37E-28 T 01-11-2018 AFULGI_00018940 68494e0c8702785f3abeca4ea79f42ee 438 Gene3D G3DSA:3.30.70.20 12 57 3.9E-7 T 01-11-2018 AFULGI_00018940 68494e0c8702785f3abeca4ea79f42ee 438 Pfam PF12838 4Fe-4S dicluster domain 198 253 5.7E-10 T 01-11-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFULGI_00018940 68494e0c8702785f3abeca4ea79f42ee 438 Pfam PF12838 4Fe-4S dicluster domain 35 88 6.3E-10 T 01-11-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFULGI_00018940 68494e0c8702785f3abeca4ea79f42ee 438 Gene3D G3DSA:3.30.70.20 218 260 1.2E-5 T 01-11-2018 AFULGI_00018940 68494e0c8702785f3abeca4ea79f42ee 438 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 74 85 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFULGI_00018940 68494e0c8702785f3abeca4ea79f42ee 438 Gene3D G3DSA:3.30.70.20 58 135 1.8E-13 T 01-11-2018 AFULGI_00018940 68494e0c8702785f3abeca4ea79f42ee 438 Gene3D G3DSA:3.30.70.20 136 217 4.5E-15 T 01-11-2018 AFULGI_00018940 68494e0c8702785f3abeca4ea79f42ee 438 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 117 128 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFULGI_00018940 68494e0c8702785f3abeca4ea79f42ee 438 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 239 250 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFULGI_00018940 68494e0c8702785f3abeca4ea79f42ee 438 Pfam PF00037 4Fe-4S binding domain 302 323 7.8E-7 T 01-11-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFULGI_00018940 68494e0c8702785f3abeca4ea79f42ee 438 Pfam PF13237 4Fe-4S dicluster domain 112 171 4.0E-6 T 01-11-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFULGI_00018940 68494e0c8702785f3abeca4ea79f42ee 438 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 35 46 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFULGI_00018940 68494e0c8702785f3abeca4ea79f42ee 438 Gene3D G3DSA:3.30.70.20 269 371 3.2E-9 T 01-11-2018 AFULGI_00018940 68494e0c8702785f3abeca4ea79f42ee 438 PIRSF PIRSF005658 4 380 6.9E-158 T 01-11-2018 AFULGI_00005260 2cda9eda79cbd35896de218e31ce9632 698 SUPERFAMILY SSF50249 12 244 1.29E-51 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold AFULGI_00005260 2cda9eda79cbd35896de218e31ce9632 698 Pfam PF00493 MCM2/3/5 family 264 605 2.2E-140 T 01-11-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 AFULGI_00005260 2cda9eda79cbd35896de218e31ce9632 698 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 317 332 1.2E-30 T 01-11-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 AFULGI_00005260 2cda9eda79cbd35896de218e31ce9632 698 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 377 391 1.2E-30 T 01-11-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 AFULGI_00005260 2cda9eda79cbd35896de218e31ce9632 698 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 429 441 1.2E-30 T 01-11-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 AFULGI_00005260 2cda9eda79cbd35896de218e31ce9632 698 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 456 464 1.2E-30 T 01-11-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 AFULGI_00005260 2cda9eda79cbd35896de218e31ce9632 698 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 405 418 1.2E-30 T 01-11-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 AFULGI_00005260 2cda9eda79cbd35896de218e31ce9632 698 SUPERFAMILY SSF52540 286 619 2.09E-46 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00005260 2cda9eda79cbd35896de218e31ce9632 698 SMART SM00382 318 470 9.0E-5 T 01-11-2018 IPR003593 AAA+ ATPase domain AFULGI_00005260 2cda9eda79cbd35896de218e31ce9632 698 SMART SM00350 97 606 3.2E-199 T 01-11-2018 IPR031327 Mini-chromosome maintenance protein AFULGI_00005260 2cda9eda79cbd35896de218e31ce9632 698 Pfam PF17207 MCM OB domain 101 226 1.2E-33 T 01-11-2018 IPR033762 MCM OB domain Reactome: R-HSA-176187|Reactome: R-HSA-176974|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962 AFULGI_00005260 2cda9eda79cbd35896de218e31ce9632 698 Gene3D G3DSA:3.40.50.300 260 610 9.9E-138 T 01-11-2018 AFULGI_00005260 2cda9eda79cbd35896de218e31ce9632 698 Gene3D G3DSA:2.20.28.10 128 176 2.5E-45 T 01-11-2018 AFULGI_00005260 2cda9eda79cbd35896de218e31ce9632 698 Gene3D G3DSA:3.30.1640.10 5 94 2.6E-13 T 01-11-2018 AFULGI_00005260 2cda9eda79cbd35896de218e31ce9632 698 Gene3D G3DSA:1.10.10.10 611 695 6.2E-27 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00005260 2cda9eda79cbd35896de218e31ce9632 698 Gene3D G3DSA:2.40.50.140 101 237 2.5E-45 T 01-11-2018 AFULGI_00000310 472bfab209740ff166bf33fa668b4381 456 SUPERFAMILY SSF53901 139 277 2.33E-12 T 01-11-2018 IPR016039 Thiolase-like GO:0003824 AFULGI_00000310 472bfab209740ff166bf33fa668b4381 456 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 333 364 1.5E-7 T 01-11-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal AFULGI_00000310 472bfab209740ff166bf33fa668b4381 456 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 92 164 1.2E-10 T 01-11-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 AFULGI_00000310 472bfab209740ff166bf33fa668b4381 456 Gene3D G3DSA:3.40.47.10 3 166 2.2E-29 T 01-11-2018 IPR016039 Thiolase-like GO:0003824 AFULGI_00000310 472bfab209740ff166bf33fa668b4381 456 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 368 437 3.0E-10 T 01-11-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal AFULGI_00000310 472bfab209740ff166bf33fa668b4381 456 SUPERFAMILY SSF53901 2 152 1.96E-24 T 01-11-2018 IPR016039 Thiolase-like GO:0003824 AFULGI_00000310 472bfab209740ff166bf33fa668b4381 456 Gene3D G3DSA:3.40.47.10 167 284 7.7E-6 T 01-11-2018 IPR016039 Thiolase-like GO:0003824 AFULGI_00000310 472bfab209740ff166bf33fa668b4381 456 SUPERFAMILY SSF50249 306 437 6.34E-20 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold AFULGI_00006710 5f68177b631f314e3b48d2d102c9a488 465 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 43 448 5.3E-149 T 01-11-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 AFULGI_00006710 5f68177b631f314e3b48d2d102c9a488 465 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 43 230 1.0E-69 T 01-11-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AFULGI_00006710 5f68177b631f314e3b48d2d102c9a488 465 SUPERFAMILY SSF51735 43 234 2.16E-54 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily AFULGI_00006710 5f68177b631f314e3b48d2d102c9a488 465 SUPERFAMILY SSF52413 345 451 2.09E-33 T 01-11-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 AFULGI_00006710 5f68177b631f314e3b48d2d102c9a488 465 SUPERFAMILY SSF48179 244 338 5.78E-33 T 01-11-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AFULGI_00006710 5f68177b631f314e3b48d2d102c9a488 465 PIRSF PIRSF500134 43 461 2.9E-151 T 01-11-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 AFULGI_00006710 5f68177b631f314e3b48d2d102c9a488 465 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 244 336 1.0E-38 T 01-11-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AFULGI_00006710 5f68177b631f314e3b48d2d102c9a488 465 Gene3D G3DSA:3.40.50.720 259 465 1.2E-80 T 01-11-2018 AFULGI_00006710 5f68177b631f314e3b48d2d102c9a488 465 Gene3D G3DSA:3.40.50.720 43 258 1.8E-77 T 01-11-2018 AFULGI_00006710 5f68177b631f314e3b48d2d102c9a488 465 PIRSF PIRSF000124 43 465 2.8E-142 T 01-11-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 AFULGI_00006710 5f68177b631f314e3b48d2d102c9a488 465 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 360 450 1.9E-27 T 01-11-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AFULGI_00006710 5f68177b631f314e3b48d2d102c9a488 465 SMART SM00984 359 453 2.6E-42 T 01-11-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AFULGI_00006500 ab4e7ba87381c53e4a2819c0f96382b1 88 SMART SM00888 3 88 9.6E-34 T 01-11-2018 IPR014038 Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain GO:0003746|GO:0006414 Reactome: R-HSA-156842 AFULGI_00006500 ab4e7ba87381c53e4a2819c0f96382b1 88 Hamap MF_00043 Elongation factor 1-beta [ef1b]. 1 88 34.609 T 01-11-2018 IPR004542 Translation elongation factor EF1B, beta chain, archaeal GO:0003746|GO:0006414 AFULGI_00006500 ab4e7ba87381c53e4a2819c0f96382b1 88 Pfam PF00736 EF-1 guanine nucleotide exchange domain 6 86 1.3E-22 T 01-11-2018 IPR014038 Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain GO:0003746|GO:0006414 Reactome: R-HSA-156842 AFULGI_00006500 ab4e7ba87381c53e4a2819c0f96382b1 88 PIRSF PIRSF006521 1 88 8.3E-31 T 01-11-2018 IPR004542 Translation elongation factor EF1B, beta chain, archaeal GO:0003746|GO:0006414 AFULGI_00006500 ab4e7ba87381c53e4a2819c0f96382b1 88 TIGRFAM TIGR00489 aEF-1_beta: translation elongation factor aEF-1 beta 1 88 2.0E-43 T 01-11-2018 IPR004542 Translation elongation factor EF1B, beta chain, archaeal GO:0003746|GO:0006414 AFULGI_00006500 ab4e7ba87381c53e4a2819c0f96382b1 88 Gene3D G3DSA:3.30.70.60 1 88 1.0E-26 T 01-11-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 AFULGI_00006500 ab4e7ba87381c53e4a2819c0f96382b1 88 SUPERFAMILY SSF54984 1 88 1.44E-24 T 01-11-2018 IPR036219 Translation elongation factor eEF-1beta-like superfamily Reactome: R-HSA-156842 AFULGI_00021420 dfd12319a066fafb2c17b0e664e8964a 322 Pfam PF13732 Domain of unknown function (DUF4162) 217 299 1.3E-8 T 01-11-2018 IPR025302 Domain of unknown function DUF4162 AFULGI_00021420 dfd12319a066fafb2c17b0e664e8964a 322 SUPERFAMILY SSF52540 3 224 8.56E-68 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00021420 dfd12319a066fafb2c17b0e664e8964a 322 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 11 301 9.9E-127 T 01-11-2018 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 AFULGI_00021420 dfd12319a066fafb2c17b0e664e8964a 322 SMART SM00382 28 212 1.1E-11 T 01-11-2018 IPR003593 AAA+ ATPase domain AFULGI_00021420 dfd12319a066fafb2c17b0e664e8964a 322 Gene3D G3DSA:3.40.50.300 1 234 9.6E-73 T 01-11-2018 AFULGI_00021420 dfd12319a066fafb2c17b0e664e8964a 322 Pfam PF00005 ABC transporter 20 162 2.1E-33 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFULGI_00021420 dfd12319a066fafb2c17b0e664e8964a 322 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFULGI_00018980 0c4e3c6ba7a56ef9ec631224a15a3899 303 Pfam PF01040 UbiA prenyltransferase family 30 261 3.8E-28 T 01-11-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 AFULGI_00018980 0c4e3c6ba7a56ef9ec631224a15a3899 303 Gene3D G3DSA:1.20.120.1780 176 302 7.5E-8 T 01-11-2018 AFULGI_00018980 0c4e3c6ba7a56ef9ec631224a15a3899 303 Gene3D G3DSA:1.10.357.140 24 175 1.0E-11 T 01-11-2018 AFULGI_00024980 8709237c2b052584fdf06239f373e6a1 863 PRINTS PR00986 Valyl-tRNA synthetase signature 36 47 2.2E-24 T 01-11-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 AFULGI_00024980 8709237c2b052584fdf06239f373e6a1 863 PRINTS PR00986 Valyl-tRNA synthetase signature 337 350 2.2E-24 T 01-11-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 AFULGI_00024980 8709237c2b052584fdf06239f373e6a1 863 PRINTS PR00986 Valyl-tRNA synthetase signature 469 487 2.2E-24 T 01-11-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 AFULGI_00024980 8709237c2b052584fdf06239f373e6a1 863 PRINTS PR00986 Valyl-tRNA synthetase signature 443 464 2.2E-24 T 01-11-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 AFULGI_00024980 8709237c2b052584fdf06239f373e6a1 863 PRINTS PR00986 Valyl-tRNA synthetase signature 222 239 2.2E-24 T 01-11-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 AFULGI_00024980 8709237c2b052584fdf06239f373e6a1 863 SUPERFAMILY SSF47323 569 773 5.23E-55 T 01-11-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFULGI_00024980 8709237c2b052584fdf06239f373e6a1 863 Gene3D G3DSA:3.40.50.620 23 518 4.3E-251 T 01-11-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFULGI_00024980 8709237c2b052584fdf06239f373e6a1 863 TIGRFAM TIGR00422 valS: valine--tRNA ligase 4 840 0.0 T 01-11-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 AFULGI_00024980 8709237c2b052584fdf06239f373e6a1 863 Hamap MF_02005 Valine--tRNA ligase [valS]. 3 767 29.831 T 01-11-2018 IPR022874 Valine-tRNA ligase, type 2 GO:0004832 KEGG: 00970+6.1.1.9 AFULGI_00024980 8709237c2b052584fdf06239f373e6a1 863 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 43 54 - T 01-11-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFULGI_00024980 8709237c2b052584fdf06239f373e6a1 863 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 15 553 2.7E-145 T 01-11-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFULGI_00024980 8709237c2b052584fdf06239f373e6a1 863 SUPERFAMILY SSF50677 192 333 2.75E-46 T 01-11-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 AFULGI_00024980 8709237c2b052584fdf06239f373e6a1 863 SUPERFAMILY SSF52374 4 566 1.58E-135 T 01-11-2018 AFULGI_00024980 8709237c2b052584fdf06239f373e6a1 863 Gene3D G3DSA:1.10.730.10 4 729 4.3E-251 T 01-11-2018 AFULGI_00024980 8709237c2b052584fdf06239f373e6a1 863 Pfam PF08264 Anticodon-binding domain of tRNA 598 743 3.6E-43 T 01-11-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 AFULGI_00024980 8709237c2b052584fdf06239f373e6a1 863 Gene3D G3DSA:3.90.740.10 172 334 4.3E-251 T 01-11-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 AFULGI_00002180 542e648555b5b87ce99fcedcf5e9d896 224 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 37 218 9.4E-21 T 01-11-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFULGI_00002180 542e648555b5b87ce99fcedcf5e9d896 224 Gene3D G3DSA:1.10.3720.10 6 220 3.0E-58 T 01-11-2018 IPR035906 MetI-like superfamily AFULGI_00002180 542e648555b5b87ce99fcedcf5e9d896 224 SUPERFAMILY SSF161098 18 204 5.1E-50 T 01-11-2018 IPR035906 MetI-like superfamily AFULGI_00002180 542e648555b5b87ce99fcedcf5e9d896 224 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 16 113 1.1E-31 T 01-11-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 AFULGI_00002670 87a3595ca43e4a7d40c06d84bba0859b 161 Gene3D G3DSA:3.30.70.20 31 102 3.9E-12 T 01-11-2018 AFULGI_00002670 87a3595ca43e4a7d40c06d84bba0859b 161 Pfam PF00037 4Fe-4S binding domain 61 83 8.6E-8 T 01-11-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFULGI_00002670 87a3595ca43e4a7d40c06d84bba0859b 161 SUPERFAMILY SSF54862 38 85 6.14E-16 T 01-11-2018 AFULGI_00002670 87a3595ca43e4a7d40c06d84bba0859b 161 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 68 79 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFULGI_00005600 7f41db7b929107945ffadd756a01b3af 422 SUPERFAMILY SSF51338 1 418 3.55E-28 T 01-11-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 AFULGI_00005600 7f41db7b929107945ffadd756a01b3af 422 Hamap MF_01281 5'-deoxyadenosine deaminase [dadD]. 1 419 44.344 T 01-11-2018 IPR023512 Deaminase MtaD/DadD GO:0019239 AFULGI_00005600 7f41db7b929107945ffadd756a01b3af 422 SUPERFAMILY SSF51556 50 341 3.58E-90 T 01-11-2018 IPR032466 Metal-dependent hydrolase AFULGI_00005600 7f41db7b929107945ffadd756a01b3af 422 Pfam PF01979 Amidohydrolase family 48 392 5.9E-76 T 01-11-2018 IPR006680 Amidohydrolase-related GO:0016787 AFULGI_00005600 7f41db7b929107945ffadd756a01b3af 422 Gene3D G3DSA:2.30.40.10 17 404 8.6E-133 T 01-11-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 AFULGI_00005600 7f41db7b929107945ffadd756a01b3af 422 Gene3D G3DSA:3.20.20.140 51 338 8.6E-133 T 01-11-2018 AFULGI_00025150 9e15cbe47670b215a79b86089897a3b7 886 Gene3D G3DSA:1.10.1200.130 1 63 2.0E-6 T 01-11-2018 AFULGI_00025150 9e15cbe47670b215a79b86089897a3b7 886 SUPERFAMILY SSF56747 3 192 1.9E-26 T 01-11-2018 AFULGI_00025150 9e15cbe47670b215a79b86089897a3b7 886 SMART SM00943 9 184 3.4E-18 T 01-11-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal AFULGI_00025150 9e15cbe47670b215a79b86089897a3b7 886 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 9 184 4.7E-23 T 01-11-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal AFULGI_00019220 94a5aface0a450ee56b4a0d3c26829b6 314 Gene3D G3DSA:1.10.287.70 8 85 1.7E-19 T 01-11-2018 AFULGI_00019220 94a5aface0a450ee56b4a0d3c26829b6 314 Pfam PF02080 TrkA-C domain 254 309 1.4E-16 T 01-11-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 AFULGI_00019220 94a5aface0a450ee56b4a0d3c26829b6 314 Gene3D G3DSA:3.30.70.1450 240 314 1.2E-15 T 01-11-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 AFULGI_00019220 94a5aface0a450ee56b4a0d3c26829b6 314 Pfam PF07885 Ion channel 13 86 3.0E-18 T 01-11-2018 IPR013099 Potassium channel domain AFULGI_00019220 94a5aface0a450ee56b4a0d3c26829b6 314 Pfam PF02254 TrkA-N domain 106 218 1.9E-30 T 01-11-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 AFULGI_00019220 94a5aface0a450ee56b4a0d3c26829b6 314 Gene3D G3DSA:3.40.50.720 97 239 3.3E-35 T 01-11-2018 AFULGI_00019220 94a5aface0a450ee56b4a0d3c26829b6 314 SUPERFAMILY SSF81324 6 127 3.14E-28 T 01-11-2018 AFULGI_00019220 94a5aface0a450ee56b4a0d3c26829b6 314 SUPERFAMILY SSF51735 101 239 2.28E-30 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily AFULGI_00019220 94a5aface0a450ee56b4a0d3c26829b6 314 SUPERFAMILY SSF116726 249 310 1.57E-15 T 01-11-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 AFULGI_00007430 8f5e0a74fd527f3fcf93532ea8c9f89f 404 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 4.6E-7 T 01-11-2018 AFULGI_00007430 8f5e0a74fd527f3fcf93532ea8c9f89f 404 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 339 355 4.6E-7 T 01-11-2018 AFULGI_00007430 8f5e0a74fd527f3fcf93532ea8c9f89f 404 Pfam PF12831 FAD dependent oxidoreductase 5 42 1.3E-9 T 01-11-2018 IPR039649 Digeranylgeranylglycerophospholipid reductase, N-terminal AFULGI_00007430 8f5e0a74fd527f3fcf93532ea8c9f89f 404 Gene3D G3DSA:3.50.50.60 260 403 2.0E-5 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFULGI_00007430 8f5e0a74fd527f3fcf93532ea8c9f89f 404 Gene3D G3DSA:3.40.50.720 2 101 2.3E-11 T 01-11-2018 AFULGI_00007430 8f5e0a74fd527f3fcf93532ea8c9f89f 404 SUPERFAMILY SSF51905 5 398 5.44E-30 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFULGI_00007430 8f5e0a74fd527f3fcf93532ea8c9f89f 404 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 104 115 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFULGI_00007430 8f5e0a74fd527f3fcf93532ea8c9f89f 404 Pfam PF00037 4Fe-4S binding domain 144 167 1.2E-5 T 01-11-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFULGI_00007430 8f5e0a74fd527f3fcf93532ea8c9f89f 404 Pfam PF00037 4Fe-4S binding domain 99 119 9.3E-5 T 01-11-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFULGI_00007430 8f5e0a74fd527f3fcf93532ea8c9f89f 404 Gene3D G3DSA:3.30.70.20 102 197 1.3E-11 T 01-11-2018 AFULGI_00006120 0ed22bda3f0c43e55923425ae0dec207 703 Pfam PF07728 AAA domain (dynein-related subfamily) 445 564 1.4E-7 T 01-11-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 AFULGI_00006120 0ed22bda3f0c43e55923425ae0dec207 703 SUPERFAMILY SSF88697 266 383 4.31E-5 T 01-11-2018 IPR015947 PUA-like superfamily AFULGI_00006120 0ed22bda3f0c43e55923425ae0dec207 703 SUPERFAMILY SSF52540 201 569 4.37E-15 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00006120 0ed22bda3f0c43e55923425ae0dec207 703 SMART SM00382 223 574 9.4E-5 T 01-11-2018 IPR003593 AAA+ ATPase domain AFULGI_00006120 0ed22bda3f0c43e55923425ae0dec207 703 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 227 263 8.4E-5 T 01-11-2018 IPR003959 ATPase, AAA-type, core GO:0005524 AFULGI_00006120 0ed22bda3f0c43e55923425ae0dec207 703 Gene3D G3DSA:3.40.50.300 208 309 1.5E-7 T 01-11-2018 AFULGI_00025500 79470b9b6a2e60da592f115cf6719fef 249 Gene3D G3DSA:3.30.1330.100 6 228 9.2E-100 T 01-11-2018 AFULGI_00025500 79470b9b6a2e60da592f115cf6719fef 249 Pfam PF01996 F420-0:Gamma-glutamyl ligase 11 220 4.0E-63 T 01-11-2018 IPR002847 Coenzyme F420:L-glutamate ligase-like domain KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 AFULGI_00025500 79470b9b6a2e60da592f115cf6719fef 249 TIGRFAM TIGR01916 F420_cofE: coenzyme F420-0:L-glutamate ligase 3 242 2.8E-111 T 01-11-2018 IPR008225 Coenzyme F420:L-glutamate ligase GO:0043773|GO:0046872|GO:0051188 KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 AFULGI_00025500 79470b9b6a2e60da592f115cf6719fef 249 Gene3D G3DSA:3.90.1660.10 50 242 9.2E-100 T 01-11-2018 AFULGI_00025500 79470b9b6a2e60da592f115cf6719fef 249 SUPERFAMILY SSF144010 4 247 3.27E-83 T 01-11-2018 AFULGI_00025500 79470b9b6a2e60da592f115cf6719fef 249 Hamap MF_01258 Coenzyme F420:L-glutamate ligase [cofE]. 3 242 45.136 T 01-11-2018 IPR023659 Coenzyme F420:L-glutamate ligase, archaeal GO:0043773|GO:0046872|GO:0051188 KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 AFULGI_00002960 0d289b60ecce447eddea72ce7d07550b 102 SUPERFAMILY SSF81301 2 101 1.47E-18 T 01-11-2018 AFULGI_00002960 0d289b60ecce447eddea72ce7d07550b 102 Pfam PF01909 Nucleotidyltransferase domain 7 100 2.0E-16 T 01-11-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 AFULGI_00002960 0d289b60ecce447eddea72ce7d07550b 102 Gene3D G3DSA:3.30.460.10 1 99 2.7E-19 T 01-11-2018 AFULGI_00004550 2b86033e5f336cf51a477169e32f448c 118 SMART SM00448 4 113 1.5E-29 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFULGI_00004550 2b86033e5f336cf51a477169e32f448c 118 Gene3D G3DSA:3.40.50.2300 1 118 1.4E-34 T 01-11-2018 AFULGI_00004550 2b86033e5f336cf51a477169e32f448c 118 Pfam PF00072 Response regulator receiver domain 6 113 2.7E-25 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFULGI_00004550 2b86033e5f336cf51a477169e32f448c 118 SUPERFAMILY SSF52172 2 118 3.7E-33 T 01-11-2018 IPR011006 CheY-like superfamily AFULGI_00025020 93903fa5015c8d2f5064e56e480ea139 328 Gene3D G3DSA:1.10.443.10 163 326 1.0E-38 T 01-11-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 AFULGI_00025020 93903fa5015c8d2f5064e56e480ea139 328 SUPERFAMILY SSF56349 81 313 2.94E-10 T 01-11-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 AFULGI_00025020 93903fa5015c8d2f5064e56e480ea139 328 Pfam PF16795 Archaeal phage integrase 166 324 3.2E-39 T 01-11-2018 IPR031857 Integrase SSV1, C-terminal AFULGI_00009080 3aa2865aa92a757874bdb013ef748327 235 SUPERFAMILY SSF52540 3 233 2.15E-61 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00009080 3aa2865aa92a757874bdb013ef748327 235 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFULGI_00009080 3aa2865aa92a757874bdb013ef748327 235 Pfam PF00005 ABC transporter 18 164 1.3E-32 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFULGI_00009080 3aa2865aa92a757874bdb013ef748327 235 SMART SM00382 27 229 9.9E-10 T 01-11-2018 IPR003593 AAA+ ATPase domain AFULGI_00009080 3aa2865aa92a757874bdb013ef748327 235 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 216 234 1.4E-5 T 01-11-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal AFULGI_00009080 3aa2865aa92a757874bdb013ef748327 235 Gene3D G3DSA:3.40.50.300 1 235 2.9E-64 T 01-11-2018 AFULGI_00014810 9f8df824506e95eabfb76856ed81e42c 77 SUPERFAMILY SSF159127 1 73 1.23E-24 T 01-11-2018 IPR037254 HupF/HypC superfamily AFULGI_00014810 9f8df824506e95eabfb76856ed81e42c 77 Gene3D G3DSA:2.40.50.970 1 73 6.7E-29 T 01-11-2018 IPR037254 HupF/HypC superfamily AFULGI_00014810 9f8df824506e95eabfb76856ed81e42c 77 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 2 9 1.2E-16 T 01-11-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC AFULGI_00014810 9f8df824506e95eabfb76856ed81e42c 77 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 17 33 1.2E-16 T 01-11-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC AFULGI_00014810 9f8df824506e95eabfb76856ed81e42c 77 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 38 54 1.2E-16 T 01-11-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC AFULGI_00014810 9f8df824506e95eabfb76856ed81e42c 77 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 56 68 1.2E-16 T 01-11-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC AFULGI_00014810 9f8df824506e95eabfb76856ed81e42c 77 ProSitePatterns PS01097 Hydrogenases expression/synthesis hupF/hypC family signature. 1 9 - T 01-11-2018 IPR019812 Hydrogenase assembly chaperone, conserved site AFULGI_00014810 9f8df824506e95eabfb76856ed81e42c 77 TIGRFAM TIGR00074 hypC_hupF: hydrogenase assembly chaperone HypC/HupF 1 75 1.7E-30 T 01-11-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC AFULGI_00014810 9f8df824506e95eabfb76856ed81e42c 77 Pfam PF01455 HupF/HypC family 1 65 1.5E-27 T 01-11-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC AFULGI_00018060 723d3c5d1f9663f5b3027f2d8c187f7a 264 SUPERFAMILY SSF103481 35 128 1.22E-8 T 01-11-2018 AFULGI_00018060 723d3c5d1f9663f5b3027f2d8c187f7a 264 SUPERFAMILY SSF103481 172 262 7.45E-15 T 01-11-2018 AFULGI_00018060 723d3c5d1f9663f5b3027f2d8c187f7a 264 Pfam PF00892 EamA-like transporter family 4 127 3.8E-14 T 01-11-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFULGI_00018060 723d3c5d1f9663f5b3027f2d8c187f7a 264 Pfam PF00892 EamA-like transporter family 134 261 2.7E-26 T 01-11-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFULGI_00007610 6612d2284d2b35b28dde9583c082974e 563 SUPERFAMILY SSF46977 430 563 9.29E-53 T 01-11-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFULGI_00007610 6612d2284d2b35b28dde9583c082974e 563 Pfam PF00890 FAD binding domain 4 382 2.0E-116 T 01-11-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFULGI_00007610 6612d2284d2b35b28dde9583c082974e 563 Gene3D G3DSA:3.50.50.60 4 395 1.0E-157 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFULGI_00007610 6612d2284d2b35b28dde9583c082974e 563 Pfam PF02910 Fumarate reductase flavoprotein C-term 438 563 1.3E-44 T 01-11-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFULGI_00007610 6612d2284d2b35b28dde9583c082974e 563 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 346 368 8.9E-9 T 01-11-2018 AFULGI_00007610 6612d2284d2b35b28dde9583c082974e 563 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 8.9E-9 T 01-11-2018 AFULGI_00007610 6612d2284d2b35b28dde9583c082974e 563 PIRSF PIRSF000171 1 558 5.1E-52 T 01-11-2018 AFULGI_00007610 6612d2284d2b35b28dde9583c082974e 563 Gene3D G3DSA:4.10.80.40 526 559 2.8E-10 T 01-11-2018 AFULGI_00007610 6612d2284d2b35b28dde9583c082974e 563 TIGRFAM TIGR01812 sdhA_frdA_Gneg: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 4 563 2.6E-265 T 01-11-2018 IPR014006 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit GO:0016627|GO:0022900|GO:0050660|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFULGI_00007610 6612d2284d2b35b28dde9583c082974e 563 SUPERFAMILY SSF56425 224 344 2.24E-44 T 01-11-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFULGI_00007610 6612d2284d2b35b28dde9583c082974e 563 Gene3D G3DSA:1.20.58.100 408 525 1.8E-39 T 01-11-2018 AFULGI_00007610 6612d2284d2b35b28dde9583c082974e 563 SUPERFAMILY SSF51905 2 405 2.97E-79 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFULGI_00007610 6612d2284d2b35b28dde9583c082974e 563 Gene3D G3DSA:3.90.700.10 234 349 1.0E-157 T 01-11-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFULGI_00022150 d3e74f2218ab456e9681507a5b20ed03 89 ProDom PD010497 ALBA DNA-BINDING DNA/RNA-BINDING RNA-BINDING ACETYLATION 3D-STRUCTURE DNA CONDENSATION AF1 SSO10B 7 89 3.0E-41 T 01-11-2018 AFULGI_00022150 d3e74f2218ab456e9681507a5b20ed03 89 Hamap MF_01122 DNA/RNA-binding protein Alba [albA]. 1 89 28.314 T 01-11-2018 IPR013795 DNA/RNA-binding protein Alba GO:0003677|GO:0003723|GO:0005737 AFULGI_00022150 d3e74f2218ab456e9681507a5b20ed03 89 TIGRFAM TIGR00285 TIGR00285: DNA-binding protein Alba 3 89 7.1E-51 T 01-11-2018 IPR013795 DNA/RNA-binding protein Alba GO:0003677|GO:0003723|GO:0005737 AFULGI_00022150 d3e74f2218ab456e9681507a5b20ed03 89 SUPERFAMILY SSF82704 4 89 4.06E-29 T 01-11-2018 IPR036882 Alba-like domain superfamily GO:0003676 AFULGI_00022150 d3e74f2218ab456e9681507a5b20ed03 89 PIRSF PIRSF028732 1 89 8.4E-42 T 01-11-2018 IPR013795 DNA/RNA-binding protein Alba GO:0003677|GO:0003723|GO:0005737 AFULGI_00022150 d3e74f2218ab456e9681507a5b20ed03 89 Pfam PF01918 Alba 5 66 8.2E-24 T 01-11-2018 IPR002775 DNA/RNA-binding protein Alba-like GO:0003676 AFULGI_00022150 d3e74f2218ab456e9681507a5b20ed03 89 Gene3D G3DSA:3.30.110.20 1 89 1.7E-40 T 01-11-2018 IPR036882 Alba-like domain superfamily GO:0003676 AFULGI_00023490 797660844c18e240fa228151b9e9b582 177 Pfam PF06510 Protein of unknown function (DUF1102) 37 176 4.6E-59 T 01-11-2018 IPR009482 Protein of unknown function DUF1102 AFULGI_00005610 3b6a0e8a20fc753283f3f002051ed94e 404 SUPERFAMILY SSF53686 3 394 2.88E-87 T 01-11-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme AFULGI_00005610 3b6a0e8a20fc753283f3f002051ed94e 404 Gene3D G3DSA:3.40.50.1100 57 378 8.3E-102 T 01-11-2018 AFULGI_00005610 3b6a0e8a20fc753283f3f002051ed94e 404 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 71 373 1.0E-63 T 01-11-2018 IPR001926 Pyridoxal-phosphate dependent enzyme AFULGI_00005610 3b6a0e8a20fc753283f3f002051ed94e 404 TIGRFAM TIGR00260 thrC: threonine synthase 55 380 3.9E-106 T 01-11-2018 IPR004450 Threonine synthase-like AFULGI_00005610 3b6a0e8a20fc753283f3f002051ed94e 404 Gene3D G3DSA:3.40.50.1100 106 203 8.3E-102 T 01-11-2018 AFULGI_00011870 6f6c56bcdb67472a4d7c882c00af6380 139 SUPERFAMILY SSF88723 2 133 3.64E-19 T 01-11-2018 IPR029060 PIN-like domain superfamily AFULGI_00011870 6f6c56bcdb67472a4d7c882c00af6380 139 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 3 138 9.776 T 01-11-2018 IPR022907 VapC family GO:0004540 AFULGI_00011870 6f6c56bcdb67472a4d7c882c00af6380 139 Gene3D G3DSA:3.40.50.1010 2 138 1.8E-12 T 01-11-2018 AFULGI_00011870 6f6c56bcdb67472a4d7c882c00af6380 139 SMART SM00670 1 130 4.0E-30 T 01-11-2018 IPR002716 PIN domain AFULGI_00011870 6f6c56bcdb67472a4d7c882c00af6380 139 Pfam PF01850 PIN domain 3 133 2.9E-25 T 01-11-2018 IPR002716 PIN domain AFULGI_00022990 2f203b9e31feaa8ced12b95a64b03d6b 537 Gene3D G3DSA:3.30.300.310 432 537 5.9E-35 T 01-11-2018 AFULGI_00022990 2f203b9e31feaa8ced12b95a64b03d6b 537 ProSitePatterns PS00455 Putative AMP-binding domain signature. 175 186 - T 01-11-2018 IPR020845 AMP-binding, conserved site AFULGI_00022990 2f203b9e31feaa8ced12b95a64b03d6b 537 Gene3D G3DSA:3.40.50.12780 2 431 3.5E-106 T 01-11-2018 AFULGI_00022990 2f203b9e31feaa8ced12b95a64b03d6b 537 SUPERFAMILY SSF56801 10 536 1.7E-129 T 01-11-2018 AFULGI_00022990 2f203b9e31feaa8ced12b95a64b03d6b 537 Pfam PF00501 AMP-binding enzyme 24 436 3.8E-88 T 01-11-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFULGI_00022990 2f203b9e31feaa8ced12b95a64b03d6b 537 Pfam PF13193 AMP-binding enzyme C-terminal domain 446 525 1.8E-21 T 01-11-2018 IPR025110 AMP-binding enzyme, C-terminal domain AFULGI_00018340 91f430e494fea4f1e1fb8e559fde1d9b 394 Pfam PF04055 Radical SAM superfamily 36 224 1.1E-13 T 01-11-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFULGI_00018340 91f430e494fea4f1e1fb8e559fde1d9b 394 SMART SM00729 31 266 7.8E-4 T 01-11-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 AFULGI_00018340 91f430e494fea4f1e1fb8e559fde1d9b 394 SUPERFAMILY SSF102114 30 262 8.63E-11 T 01-11-2018 AFULGI_00012940 f5b32417145ea51e2da18062744711d9 479 Gene3D G3DSA:3.40.50.300 1 165 6.0E-39 T 01-11-2018 AFULGI_00012940 f5b32417145ea51e2da18062744711d9 479 SMART SM00382 35 167 1.8E-8 T 01-11-2018 IPR003593 AAA+ ATPase domain AFULGI_00012940 f5b32417145ea51e2da18062744711d9 479 SUPERFAMILY SSF52540 2 226 1.3E-43 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00012940 f5b32417145ea51e2da18062744711d9 479 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 39 162 1.7E-14 T 01-11-2018 IPR003959 ATPase, AAA-type, core GO:0005524 AFULGI_00012940 f5b32417145ea51e2da18062744711d9 479 Hamap MF_01508 Replication factor C large subunit [rfcL]. 1 463 35.919 T 01-11-2018 IPR023935 Replication factor C, large subunit AFULGI_00012940 f5b32417145ea51e2da18062744711d9 479 Gene3D G3DSA:1.10.8.60 167 230 1.0E-12 T 01-11-2018 AFULGI_00023110 b5a2ebdcd7cdae372afd4e9a4e78ee86 61 SUPERFAMILY SSF143560 1 60 1.7E-16 T 01-11-2018 IPR036839 7,8-dihydroneopterin aldolase (MptD) superfamily GO:0004150 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 AFULGI_00023110 b5a2ebdcd7cdae372afd4e9a4e78ee86 61 Gene3D G3DSA:3.30.1300.20 1 61 1.1E-12 T 01-11-2018 IPR036839 7,8-dihydroneopterin aldolase (MptD) superfamily GO:0004150 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 AFULGI_00023110 b5a2ebdcd7cdae372afd4e9a4e78ee86 61 Pfam PF04038 Dihydroneopterin aldolase 2 60 2.0E-12 T 01-11-2018 IPR007181 Dihydroneopterin aldolase MtpD, C-terminal domain KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 AFULGI_00011470 4f8f79b27a5fbd33f187668185b9d60e 244 Pfam PF06745 KaiC 22 238 1.1E-28 T 01-11-2018 IPR014774 KaiC-like domain AFULGI_00011470 4f8f79b27a5fbd33f187668185b9d60e 244 SUPERFAMILY SSF52540 11 236 5.15E-35 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00011470 4f8f79b27a5fbd33f187668185b9d60e 244 Gene3D G3DSA:3.40.50.300 13 241 1.9E-53 T 01-11-2018 AFULGI_00021490 11f8f0a6902c9691db5950bd7bc83fc8 86 SUPERFAMILY SSF55315 4 84 6.06E-23 T 01-11-2018 IPR029064 50S ribosomal protein L30e-like AFULGI_00021490 11f8f0a6902c9691db5950bd7bc83fc8 86 Gene3D G3DSA:3.30.1330.30 1 86 2.8E-28 T 01-11-2018 IPR029064 50S ribosomal protein L30e-like AFULGI_00021490 11f8f0a6902c9691db5950bd7bc83fc8 86 ProSitePatterns PS00709 Ribosomal protein L30e signature 1. 14 38 - T 01-11-2018 IPR022991 Ribosomal protein L30e, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00021490 11f8f0a6902c9691db5950bd7bc83fc8 86 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 3 85 4.3E-17 T 01-11-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 AFULGI_00021490 11f8f0a6902c9691db5950bd7bc83fc8 86 Hamap MF_00481 50S ribosomal protein L30e [rpl30e]. 2 85 21.148 T 01-11-2018 IPR000231 Ribosomal protein L30e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00018490 3fd8366e668c1601592d00b37bb79f82 248 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 1 246 36.061 T 01-11-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 AFULGI_00018490 3fd8366e668c1601592d00b37bb79f82 248 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 3 244 8.7E-99 T 01-11-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 AFULGI_00018490 3fd8366e668c1601592d00b37bb79f82 248 SUPERFAMILY SSF51366 5 240 2.07E-77 T 01-11-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 AFULGI_00018490 3fd8366e668c1601592d00b37bb79f82 248 Gene3D G3DSA:3.20.20.70 3 247 3.3E-88 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFULGI_00018490 3fd8366e668c1601592d00b37bb79f82 248 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 35 48 - T 01-11-2018 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 AFULGI_00018490 3fd8366e668c1601592d00b37bb79f82 248 Pfam PF00290 Tryptophan synthase alpha chain 5 243 2.6E-76 T 01-11-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 AFULGI_00026900 38a979678d660b0624a05229b27b6bd6 319 Gene3D G3DSA:1.10.8.300 201 309 2.6E-35 T 01-11-2018 AFULGI_00026900 38a979678d660b0624a05229b27b6bd6 319 Gene3D G3DSA:3.40.50.300 19 184 6.9E-41 T 01-11-2018 AFULGI_00026900 38a979678d660b0624a05229b27b6bd6 319 SUPERFAMILY SSF52540 11 284 2.04E-42 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00026900 38a979678d660b0624a05229b27b6bd6 319 PIRSF PIRSF002849 1 314 6.1E-130 T 01-11-2018 AFULGI_00026900 38a979678d660b0624a05229b27b6bd6 319 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 39 166 4.0E-61 T 01-11-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 AFULGI_00011860 f97c3032a7aa64436f527695d6f095e6 59 Pfam PF01954 Protein of unknown function DUF104 1 55 8.7E-21 T 01-11-2018 IPR008203 Uncharacterised protein family UPF0165 AFULGI_00011860 f97c3032a7aa64436f527695d6f095e6 59 Gene3D G3DSA:4.10.1150.10 1 58 1.2E-18 T 01-11-2018 IPR024069 AF2212-like domain superfamily AFULGI_00011860 f97c3032a7aa64436f527695d6f095e6 59 SUPERFAMILY SSF141694 1 57 4.18E-16 T 01-11-2018 AFULGI_00001230 083097d7bf2d0ab43e4608b9628fbbbe 475 Pfam PF01925 Sulfite exporter TauE/SafE 28 296 1.9E-34 T 01-11-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 AFULGI_00023240 ebb71b3d53438842969dc7b30ccef503 113 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 9 73 16.19 T 01-11-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 AFULGI_00023240 ebb71b3d53438842969dc7b30ccef503 113 Pfam PF02416 mttA/Hcf106 family 12 62 2.1E-21 T 01-11-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 AFULGI_00023240 ebb71b3d53438842969dc7b30ccef503 113 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 12 56 1.6E-21 T 01-11-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 AFULGI_00009880 4e0d34dd0b07ae6beffedb039fe07666 270 Gene3D G3DSA:3.80.30.30 51 181 1.5E-8 T 01-11-2018 AFULGI_00009880 4e0d34dd0b07ae6beffedb039fe07666 270 Pfam PF04055 Radical SAM superfamily 24 177 1.6E-11 T 01-11-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFULGI_00009880 4e0d34dd0b07ae6beffedb039fe07666 270 SUPERFAMILY SSF102114 5 173 4.45E-6 T 01-11-2018 AFULGI_00026030 362bae59f58d968b7632c33ba167ce83 112 Gene3D G3DSA:3.30.460.10 2 104 6.1E-14 T 01-11-2018 AFULGI_00026030 362bae59f58d968b7632c33ba167ce83 112 Pfam PF01909 Nucleotidyltransferase domain 12 68 2.4E-10 T 01-11-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 AFULGI_00026030 362bae59f58d968b7632c33ba167ce83 112 SUPERFAMILY SSF81301 3 92 2.16E-14 T 01-11-2018 AFULGI_00015280 d21602fc3b7381f4b2cec87eb7941563 476 Pfam PF14251 Domain of unknown function (DUF4346) 416 466 2.6E-9 T 01-11-2018 IPR025595 Domain of unknown function DUF4346 AFULGI_00015280 d21602fc3b7381f4b2cec87eb7941563 476 Gene3D G3DSA:3.20.20.20 142 303 1.1E-8 T 01-11-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFULGI_00015280 d21602fc3b7381f4b2cec87eb7941563 476 TIGRFAM TIGR00284 TIGR00284: dihydropteroate synthase-related protein 1 469 1.1E-91 T 01-11-2018 IPR005236 Dihydropteroate synthase-related protein synthase-related protein AFULGI_00015280 d21602fc3b7381f4b2cec87eb7941563 476 Pfam PF00809 Pterin binding enzyme 148 240 1.5E-8 T 01-11-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFULGI_00015280 d21602fc3b7381f4b2cec87eb7941563 476 SUPERFAMILY SSF51717 126 342 2.09E-28 T 01-11-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFULGI_00004720 85b7198e89290240317ba386ee98ac0e 786 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 26 457 5.0E-165 T 01-11-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AFULGI_00004720 85b7198e89290240317ba386ee98ac0e 786 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 639 682 1.2E-13 T 01-11-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 AFULGI_00004720 85b7198e89290240317ba386ee98ac0e 786 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 604 639 2.0 T 01-11-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 AFULGI_00004720 85b7198e89290240317ba386ee98ac0e 786 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 688 736 1.5E-11 T 01-11-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 AFULGI_00004720 85b7198e89290240317ba386ee98ac0e 786 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 541 588 2.4E-9 T 01-11-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 AFULGI_00004720 85b7198e89290240317ba386ee98ac0e 786 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 494 532 1.8E-10 T 01-11-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 AFULGI_00004720 85b7198e89290240317ba386ee98ac0e 786 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 739 769 2.1E-5 T 01-11-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 AFULGI_00004720 85b7198e89290240317ba386ee98ac0e 786 Gene3D G3DSA:3.90.199.10 26 473 2.2E-211 T 01-11-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 AFULGI_00004720 85b7198e89290240317ba386ee98ac0e 786 SMART SM00434 5 452 5.3E-285 T 01-11-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AFULGI_00004720 85b7198e89290240317ba386ee98ac0e 786 Gene3D G3DSA:2.120.10.90 484 782 2.1E-80 T 01-11-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal AFULGI_00004720 85b7198e89290240317ba386ee98ac0e 786 SUPERFAMILY SSF56719 24 475 2.35E-177 T 01-11-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 AFULGI_00004720 85b7198e89290240317ba386ee98ac0e 786 Gene3D G3DSA:1.10.268.10 357 446 2.2E-211 T 01-11-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily GO:0003677|GO:0003918|GO:0005524 Reactome: R-HSA-4615885 AFULGI_00004720 85b7198e89290240317ba386ee98ac0e 786 SUPERFAMILY SSF101904 486 771 2.75E-71 T 01-11-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal AFULGI_00004720 85b7198e89290240317ba386ee98ac0e 786 Gene3D G3DSA:3.30.1360.40 230 320 2.2E-211 T 01-11-2018 AFULGI_00004720 85b7198e89290240317ba386ee98ac0e 786 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 6 771 0.0 T 01-11-2018 AFULGI_00020360 5cd4cfd4352fd99f8309d2bcd43ff0a3 191 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 62 125 5.5E-18 T 01-11-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 AFULGI_00020360 5cd4cfd4352fd99f8309d2bcd43ff0a3 191 Gene3D G3DSA:1.10.10.10 1 65 9.5E-22 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00020360 5cd4cfd4352fd99f8309d2bcd43ff0a3 191 SUPERFAMILY SSF46785 2 60 2.33E-12 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00020360 5cd4cfd4352fd99f8309d2bcd43ff0a3 191 SMART SM00529 23 123 1.3E-45 T 01-11-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 AFULGI_00020360 5cd4cfd4352fd99f8309d2bcd43ff0a3 191 Gene3D G3DSA:1.10.60.10 66 120 2.8E-9 T 01-11-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 AFULGI_00020360 5cd4cfd4352fd99f8309d2bcd43ff0a3 191 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 1 59 7.7E-27 T 01-11-2018 IPR022687 DTXR-type HTH domain GO:0003677 AFULGI_00020360 5cd4cfd4352fd99f8309d2bcd43ff0a3 191 SUPERFAMILY SSF47979 62 131 3.66E-11 T 01-11-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 AFULGI_00007810 d1f26d0b6a7afdf62cc207fb5ae33e7e 438 Pfam PF02272 DHHA1 domain 324 432 1.9E-19 T 01-11-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 AFULGI_00007810 d1f26d0b6a7afdf62cc207fb5ae33e7e 438 SUPERFAMILY SSF64182 11 436 8.24E-57 T 01-11-2018 IPR038763 DHH phosphoesterase superfamily AFULGI_00007810 d1f26d0b6a7afdf62cc207fb5ae33e7e 438 Gene3D G3DSA:3.90.1640.30 3 192 1.1E-17 T 01-11-2018 AFULGI_00007810 d1f26d0b6a7afdf62cc207fb5ae33e7e 438 Gene3D G3DSA:3.10.310.30 344 436 4.3E-5 T 01-11-2018 AFULGI_00026530 cbfe19a4300532ea17d10abe7675176b 84 ProDom PD029943 UPF0147 ARCHAEAL PF0239 ST0460.1 MM1385 CYTOSOLIC SACI_0891 TV0625 APES069 TA0600 6 81 2.0E-36 T 01-11-2018 IPR005354 Uncharacterised protein family UPF0147 AFULGI_00026530 cbfe19a4300532ea17d10abe7675176b 84 Gene3D G3DSA:1.20.1440.50 2 82 7.1E-31 T 01-11-2018 IPR023130 Ta0600-like superfamily AFULGI_00026530 cbfe19a4300532ea17d10abe7675176b 84 SUPERFAMILY SSF158436 3 82 3.66E-28 T 01-11-2018 AFULGI_00026530 cbfe19a4300532ea17d10abe7675176b 84 Pfam PF03685 Uncharacterised protein family (UPF0147) 4 81 2.2E-31 T 01-11-2018 IPR005354 Uncharacterised protein family UPF0147 AFULGI_00026530 cbfe19a4300532ea17d10abe7675176b 84 Hamap MF_00342 UPF0147 protein . 2 82 28.616 T 01-11-2018 IPR005354 Uncharacterised protein family UPF0147 AFULGI_00012200 375674dce6dfcc51431ba729516e6459 66 Gene3D G3DSA:3.40.50.1820 1 65 4.4E-8 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold AFULGI_00012200 375674dce6dfcc51431ba729516e6459 66 SUPERFAMILY SSF53474 1 63 1.05E-7 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold AFULGI_00009780 a89f820ab49d7698a85b894be552bf1f 310 Pfam PF02653 Branched-chain amino acid transport system / permease component 12 283 2.8E-34 T 01-11-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 AFULGI_00009780 a89f820ab49d7698a85b894be552bf1f 310 SUPERFAMILY SSF81345 47 203 2.48E-6 T 01-11-2018 IPR037294 ABC transporter, BtuC-like AFULGI_00007140 4c72186bc4176ea5a837e339dfa5a234 1018 Pfam PF08264 Anticodon-binding domain of tRNA 667 817 1.6E-35 T 01-11-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 AFULGI_00007140 4c72186bc4176ea5a837e339dfa5a234 1018 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 386 401 9.4E-32 T 01-11-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 AFULGI_00007140 4c72186bc4176ea5a837e339dfa5a234 1018 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 36 47 9.4E-32 T 01-11-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 AFULGI_00007140 4c72186bc4176ea5a837e339dfa5a234 1018 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 214 237 9.4E-32 T 01-11-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 AFULGI_00007140 4c72186bc4176ea5a837e339dfa5a234 1018 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 545 554 9.4E-32 T 01-11-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 AFULGI_00007140 4c72186bc4176ea5a837e339dfa5a234 1018 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 506 519 9.4E-32 T 01-11-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 AFULGI_00007140 4c72186bc4176ea5a837e339dfa5a234 1018 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 15 625 4.2E-198 T 01-11-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFULGI_00007140 4c72186bc4176ea5a837e339dfa5a234 1018 SUPERFAMILY SSF52374 3 633 1.71E-141 T 01-11-2018 AFULGI_00007140 4c72186bc4176ea5a837e339dfa5a234 1018 SUPERFAMILY SSF50677 192 388 1.05E-53 T 01-11-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 AFULGI_00007140 4c72186bc4176ea5a837e339dfa5a234 1018 Gene3D G3DSA:3.90.740.10 190 392 4.3E-242 T 01-11-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 AFULGI_00007140 4c72186bc4176ea5a837e339dfa5a234 1018 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 43 54 - T 01-11-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFULGI_00007140 4c72186bc4176ea5a837e339dfa5a234 1018 Gene3D G3DSA:3.40.50.620 12 612 4.3E-242 T 01-11-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFULGI_00007140 4c72186bc4176ea5a837e339dfa5a234 1018 Gene3D G3DSA:1.10.730.10 629 809 1.2E-47 T 01-11-2018 AFULGI_00007140 4c72186bc4176ea5a837e339dfa5a234 1018 SUPERFAMILY SSF47323 637 865 1.05E-53 T 01-11-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFULGI_00007140 4c72186bc4176ea5a837e339dfa5a234 1018 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 3 833 0.0 T 01-11-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 AFULGI_00007140 4c72186bc4176ea5a837e339dfa5a234 1018 Hamap MF_02003 Isoleucine--tRNA ligase [ileS]. 2 1010 13.421 T 01-11-2018 IPR023586 Isoleucine-tRNA ligase, type 2 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 AFULGI_00026240 32df74d1ece1df041d58a61082eed8b7 437 SUPERFAMILY SSF53335 136 435 7.5E-56 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFULGI_00026240 32df74d1ece1df041d58a61082eed8b7 437 Gene3D G3DSA:3.40.50.150 144 435 3.7E-67 T 01-11-2018 AFULGI_00026240 32df74d1ece1df041d58a61082eed8b7 437 SUPERFAMILY SSF48013 13 151 1.7E-22 T 01-11-2018 IPR035926 NusB-like superfamily AFULGI_00026240 32df74d1ece1df041d58a61082eed8b7 437 Pfam PF01189 16S rRNA methyltransferase RsmB/F 244 433 2.3E-40 T 01-11-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 AFULGI_00026240 32df74d1ece1df041d58a61082eed8b7 437 Gene3D G3DSA:1.10.940.10 11 143 6.5E-17 T 01-11-2018 IPR035926 NusB-like superfamily AFULGI_00026240 32df74d1ece1df041d58a61082eed8b7 437 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 364 380 7.8E-20 T 01-11-2018 IPR023267 RNA (C5-cytosine) methyltransferase AFULGI_00026240 32df74d1ece1df041d58a61082eed8b7 437 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 225 239 7.8E-20 T 01-11-2018 IPR023267 RNA (C5-cytosine) methyltransferase AFULGI_00026240 32df74d1ece1df041d58a61082eed8b7 437 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 317 329 7.8E-20 T 01-11-2018 IPR023267 RNA (C5-cytosine) methyltransferase AFULGI_00026240 32df74d1ece1df041d58a61082eed8b7 437 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 418 435 7.8E-20 T 01-11-2018 IPR023267 RNA (C5-cytosine) methyltransferase AFULGI_00026240 32df74d1ece1df041d58a61082eed8b7 437 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 254 264 7.8E-20 T 01-11-2018 IPR023267 RNA (C5-cytosine) methyltransferase AFULGI_00026240 32df74d1ece1df041d58a61082eed8b7 437 Pfam PF01029 NusB family 13 129 1.3E-15 T 01-11-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 AFULGI_00001030 a319fc369e9209ce14a6d2dc5fe9334e 298 Gene3D G3DSA:3.40.50.1370 131 284 1.6E-121 T 01-11-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 AFULGI_00001030 a319fc369e9209ce14a6d2dc5fe9334e 298 PRINTS PR00101 Aspartate carbamoyltransferase signature 37 59 7.3E-39 T 01-11-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AFULGI_00001030 a319fc369e9209ce14a6d2dc5fe9334e 298 PRINTS PR00101 Aspartate carbamoyltransferase signature 76 85 7.3E-39 T 01-11-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AFULGI_00001030 a319fc369e9209ce14a6d2dc5fe9334e 298 PRINTS PR00101 Aspartate carbamoyltransferase signature 130 147 7.3E-39 T 01-11-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AFULGI_00001030 a319fc369e9209ce14a6d2dc5fe9334e 298 PRINTS PR00101 Aspartate carbamoyltransferase signature 278 292 7.3E-39 T 01-11-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AFULGI_00001030 a319fc369e9209ce14a6d2dc5fe9334e 298 PRINTS PR00101 Aspartate carbamoyltransferase signature 217 226 7.3E-39 T 01-11-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AFULGI_00001030 a319fc369e9209ce14a6d2dc5fe9334e 298 PRINTS PR00101 Aspartate carbamoyltransferase signature 256 261 7.3E-39 T 01-11-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AFULGI_00001030 a319fc369e9209ce14a6d2dc5fe9334e 298 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 150 294 1.4E-30 T 01-11-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 AFULGI_00001030 a319fc369e9209ce14a6d2dc5fe9334e 298 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 131 142 8.1E-23 T 01-11-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 AFULGI_00001030 a319fc369e9209ce14a6d2dc5fe9334e 298 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 262 285 8.1E-23 T 01-11-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 AFULGI_00001030 a319fc369e9209ce14a6d2dc5fe9334e 298 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 47 66 8.1E-23 T 01-11-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 AFULGI_00001030 a319fc369e9209ce14a6d2dc5fe9334e 298 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 252 261 8.1E-23 T 01-11-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 AFULGI_00001030 a319fc369e9209ce14a6d2dc5fe9334e 298 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 2 143 8.7E-54 T 01-11-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 AFULGI_00001030 a319fc369e9209ce14a6d2dc5fe9334e 298 SUPERFAMILY SSF53671 1 297 6.55E-101 T 01-11-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 AFULGI_00001030 a319fc369e9209ce14a6d2dc5fe9334e 298 Gene3D G3DSA:3.40.50.1370 3 293 1.6E-121 T 01-11-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 AFULGI_00001030 a319fc369e9209ce14a6d2dc5fe9334e 298 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 47 54 - T 01-11-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 AFULGI_00001030 a319fc369e9209ce14a6d2dc5fe9334e 298 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 1 298 39.482 T 01-11-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AFULGI_00001030 a319fc369e9209ce14a6d2dc5fe9334e 298 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 2 297 3.9E-137 T 01-11-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AFULGI_00004930 eec9e2480f34008b33b004f917f242ea 245 Pfam PF09876 Predicted metal-binding protein (DUF2103) 141 236 1.1E-36 T 01-11-2018 IPR018664 Protein of unknown function DUF2103, metal-binding AFULGI_00019700 8c69a3c431f83ad4767397995be013b2 159 SUPERFAMILY SSF55021 78 158 5.27E-29 T 01-11-2018 AFULGI_00019700 8c69a3c431f83ad4767397995be013b2 159 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 1 76 1.0E-35 T 01-11-2018 AFULGI_00019700 8c69a3c431f83ad4767397995be013b2 159 SUPERFAMILY SSF55021 2 75 1.22E-24 T 01-11-2018 AFULGI_00019700 8c69a3c431f83ad4767397995be013b2 159 Gene3D G3DSA:3.30.70.260 1 79 1.1E-37 T 01-11-2018 AFULGI_00019700 8c69a3c431f83ad4767397995be013b2 159 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 2 157 3.0E-74 T 01-11-2018 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 AFULGI_00019700 8c69a3c431f83ad4767397995be013b2 159 Gene3D G3DSA:3.30.70.1150 82 159 8.1E-33 T 01-11-2018 IPR027271 Acetolactate synthase/Transcription factor NikR, C-terminal AFULGI_00019700 8c69a3c431f83ad4767397995be013b2 159 Pfam PF13710 ACT domain 12 73 4.0E-19 T 01-11-2018 AFULGI_00019700 8c69a3c431f83ad4767397995be013b2 159 Pfam PF10369 Small subunit of acetolactate synthase 83 156 1.4E-31 T 01-11-2018 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 AFULGI_00018910 341cbb0a412df76b24f7e237254aa91a 254 SUPERFAMILY SSF52096 3 254 2.2E-77 T 01-11-2018 IPR029045 ClpP/crotonase-like domain superfamily AFULGI_00018910 341cbb0a412df76b24f7e237254aa91a 254 Gene3D G3DSA:3.90.226.10 3 197 1.5E-63 T 01-11-2018 AFULGI_00018910 341cbb0a412df76b24f7e237254aa91a 254 Gene3D G3DSA:1.10.12.10 200 254 1.1E-13 T 01-11-2018 IPR014748 Enoyl-CoA hydratase, C-terminal AFULGI_00018910 341cbb0a412df76b24f7e237254aa91a 254 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 254 1.5E-56 T 01-11-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 AFULGI_00022180 4d2000d18370a1b8e1b7ebd1f7f6b406 251 TIGRFAM TIGR00241 CoA_E_activ: putative CoA-substrate-specific enzyme activase 2 250 1.2E-117 T 01-11-2018 IPR008275 CoA enzyme activase AFULGI_00022180 4d2000d18370a1b8e1b7ebd1f7f6b406 251 Gene3D G3DSA:3.30.420.40 95 234 1.5E-88 T 01-11-2018 AFULGI_00022180 4d2000d18370a1b8e1b7ebd1f7f6b406 251 SUPERFAMILY SSF53067 1 251 5.37E-43 T 01-11-2018 AFULGI_00022180 4d2000d18370a1b8e1b7ebd1f7f6b406 251 Gene3D G3DSA:3.30.420.40 5 251 1.5E-88 T 01-11-2018 AFULGI_00022180 4d2000d18370a1b8e1b7ebd1f7f6b406 251 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 5 251 2.6E-80 T 01-11-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 AFULGI_00007820 f328f56e258b630b6ab5b4f72680905e 462 Pfam PF01842 ACT domain 404 455 5.0E-10 T 01-11-2018 IPR002912 ACT domain AFULGI_00007820 f328f56e258b630b6ab5b4f72680905e 462 Pfam PF01842 ACT domain 335 383 3.5E-8 T 01-11-2018 IPR002912 ACT domain AFULGI_00007820 f328f56e258b630b6ab5b4f72680905e 462 Gene3D G3DSA:3.30.2130.10 385 461 1.2E-25 T 01-11-2018 AFULGI_00007820 f328f56e258b630b6ab5b4f72680905e 462 Pfam PF00696 Amino acid kinase family 1 290 2.3E-56 T 01-11-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 AFULGI_00007820 f328f56e258b630b6ab5b4f72680905e 462 Gene3D G3DSA:3.30.70.260 306 384 3.5E-12 T 01-11-2018 AFULGI_00007820 f328f56e258b630b6ab5b4f72680905e 462 SUPERFAMILY SSF55021 389 461 3.05E-24 T 01-11-2018 AFULGI_00007820 f328f56e258b630b6ab5b4f72680905e 462 SUPERFAMILY SSF53633 2 303 1.2E-86 T 01-11-2018 IPR036393 Acetylglutamate kinase-like superfamily AFULGI_00007820 f328f56e258b630b6ab5b4f72680905e 462 Gene3D G3DSA:3.40.1160.10 1 303 5.0E-108 T 01-11-2018 IPR036393 Acetylglutamate kinase-like superfamily AFULGI_00007820 f328f56e258b630b6ab5b4f72680905e 462 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 1 459 1.1E-162 T 01-11-2018 IPR001341 Aspartate kinase GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 AFULGI_00007820 f328f56e258b630b6ab5b4f72680905e 462 TIGRFAM TIGR00656 asp_kin_monofn: aspartate kinase, monofunctional class 3 458 4.4E-130 T 01-11-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 AFULGI_00007820 f328f56e258b630b6ab5b4f72680905e 462 SUPERFAMILY SSF55021 311 382 6.36E-14 T 01-11-2018 AFULGI_00007820 f328f56e258b630b6ab5b4f72680905e 462 PIRSF PIRSF000726 1 462 1.0E-129 T 01-11-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 AFULGI_00014110 ae7b7c1980aacb2e50d3a9416f1255e2 326 SUPERFAMILY SSF47954 137 231 1.73E-29 T 01-11-2018 IPR036915 Cyclin-like superfamily AFULGI_00014110 ae7b7c1980aacb2e50d3a9416f1255e2 326 SMART SM00385 143 224 5.2E-14 T 01-11-2018 IPR013763 Cyclin-like AFULGI_00014110 ae7b7c1980aacb2e50d3a9416f1255e2 326 SMART SM00385 237 318 4.8E-14 T 01-11-2018 IPR013763 Cyclin-like AFULGI_00014110 ae7b7c1980aacb2e50d3a9416f1255e2 326 ProSitePatterns PS00782 Transcription factor TFIIB repeat signature. 271 286 - T 01-11-2018 IPR023486 Transcription factor TFIIB, conserved site Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 AFULGI_00014110 ae7b7c1980aacb2e50d3a9416f1255e2 326 SUPERFAMILY SSF47954 234 324 3.61E-33 T 01-11-2018 IPR036915 Cyclin-like superfamily AFULGI_00014110 ae7b7c1980aacb2e50d3a9416f1255e2 326 Gene3D G3DSA:1.10.472.10 234 326 1.3E-29 T 01-11-2018 AFULGI_00014110 ae7b7c1980aacb2e50d3a9416f1255e2 326 SUPERFAMILY SSF57783 27 73 1.42E-17 T 01-11-2018 AFULGI_00014110 ae7b7c1980aacb2e50d3a9416f1255e2 326 Hamap MF_00383 Transcription initiation factor IIB [tfb]. 24 324 47.949 T 01-11-2018 IPR023484 Transcription initiation factor TFIIB, archaea AFULGI_00014110 ae7b7c1980aacb2e50d3a9416f1255e2 326 Pfam PF08271 TFIIB zinc-binding 29 70 2.7E-20 T 01-11-2018 IPR013137 Zinc finger, TFIIB-type AFULGI_00014110 ae7b7c1980aacb2e50d3a9416f1255e2 326 ProSitePatterns PS00782 Transcription factor TFIIB repeat signature. 177 192 - T 01-11-2018 IPR023486 Transcription factor TFIIB, conserved site Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 AFULGI_00014110 ae7b7c1980aacb2e50d3a9416f1255e2 326 PRINTS PR00685 Transcription initiation factor IIB signature 42 62 8.1E-69 T 01-11-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 AFULGI_00014110 ae7b7c1980aacb2e50d3a9416f1255e2 326 PRINTS PR00685 Transcription initiation factor IIB signature 77 98 8.1E-69 T 01-11-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 AFULGI_00014110 ae7b7c1980aacb2e50d3a9416f1255e2 326 PRINTS PR00685 Transcription initiation factor IIB signature 64 77 8.1E-69 T 01-11-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 AFULGI_00014110 ae7b7c1980aacb2e50d3a9416f1255e2 326 PRINTS PR00685 Transcription initiation factor IIB signature 211 226 8.1E-69 T 01-11-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 AFULGI_00014110 ae7b7c1980aacb2e50d3a9416f1255e2 326 PRINTS PR00685 Transcription initiation factor IIB signature 272 288 8.1E-69 T 01-11-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 AFULGI_00014110 ae7b7c1980aacb2e50d3a9416f1255e2 326 PRINTS PR00685 Transcription initiation factor IIB signature 304 318 8.1E-69 T 01-11-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 AFULGI_00014110 ae7b7c1980aacb2e50d3a9416f1255e2 326 PRINTS PR00685 Transcription initiation factor IIB signature 185 204 8.1E-69 T 01-11-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 AFULGI_00014110 ae7b7c1980aacb2e50d3a9416f1255e2 326 PRINTS PR00685 Transcription initiation factor IIB signature 238 256 8.1E-69 T 01-11-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 AFULGI_00014110 ae7b7c1980aacb2e50d3a9416f1255e2 326 Pfam PF00382 Transcription factor TFIIB repeat 239 309 7.1E-22 T 01-11-2018 IPR013150 Transcription factor TFIIB, cyclin-like domain GO:0017025 AFULGI_00014110 ae7b7c1980aacb2e50d3a9416f1255e2 326 Pfam PF00382 Transcription factor TFIIB repeat 146 215 1.0E-20 T 01-11-2018 IPR013150 Transcription factor TFIIB, cyclin-like domain GO:0017025 AFULGI_00014110 ae7b7c1980aacb2e50d3a9416f1255e2 326 Gene3D G3DSA:1.10.472.170 29 226 2.8E-73 T 01-11-2018 AFULGI_00021720 54e3590e96b3350f8f680e062576c180 232 SUPERFAMILY SSF55174 44 88 1.23E-7 T 01-11-2018 AFULGI_00021720 54e3590e96b3350f8f680e062576c180 232 PIRSF PIRSF002116 1 231 8.2E-91 T 01-11-2018 IPR000876 Ribosomal protein S4e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00021720 54e3590e96b3350f8f680e062576c180 232 Pfam PF00900 Ribosomal family S4e 89 159 3.0E-21 T 01-11-2018 IPR013845 Ribosomal protein S4e, central region Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00021720 54e3590e96b3350f8f680e062576c180 232 SMART SM00363 36 99 0.0038 T 01-11-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00021720 54e3590e96b3350f8f680e062576c180 232 Hamap MF_00485 30S ribosomal protein S4e [rps4e]. 1 230 40.505 T 01-11-2018 IPR000876 Ribosomal protein S4e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00021720 54e3590e96b3350f8f680e062576c180 232 ProSitePatterns PS00528 Ribosomal protein S4e signature. 2 16 - T 01-11-2018 IPR018199 Ribosomal protein S4e, N-terminal, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00021720 54e3590e96b3350f8f680e062576c180 232 ProDom PD002667 RIBOSOMAL RIBONUCLEOPROTEIN RNA-BINDING 40S S4 S4 S4E 30S ISOFORM X 81 170 9.0E-45 T 01-11-2018 IPR013845 Ribosomal protein S4e, central region Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00021720 54e3590e96b3350f8f680e062576c180 232 Gene3D G3DSA:2.40.50.740 113 164 1.8E-19 T 01-11-2018 IPR038237 Ribosomal protein S4e, central domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00021720 54e3590e96b3350f8f680e062576c180 232 Gene3D G3DSA:2.30.30.30 166 223 1.7E-21 T 01-11-2018 IPR014722 Ribosomal protein L2, domain 2 AFULGI_00021720 54e3590e96b3350f8f680e062576c180 232 SMART SM00739 164 191 0.0019 T 01-11-2018 IPR005824 KOW AFULGI_00021720 54e3590e96b3350f8f680e062576c180 232 Pfam PF01479 S4 domain 44 83 3.6E-10 T 01-11-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00021720 54e3590e96b3350f8f680e062576c180 232 Pfam PF08071 RS4NT (NUC023) domain 2 33 1.7E-12 T 01-11-2018 IPR013843 Ribosomal protein S4e, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00021720 54e3590e96b3350f8f680e062576c180 232 Gene3D G3DSA:3.10.290.40 1 109 4.9E-40 T 01-11-2018 AFULGI_00013360 5e02a3e25d424e6e1b28182ed2d60cef 769 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 576 587 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFULGI_00013360 5e02a3e25d424e6e1b28182ed2d60cef 769 Pfam PF00037 4Fe-4S binding domain 285 305 1.7E-4 T 01-11-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFULGI_00013360 5e02a3e25d424e6e1b28182ed2d60cef 769 SUPERFAMILY SSF54862 526 624 3.94E-21 T 01-11-2018 AFULGI_00013360 5e02a3e25d424e6e1b28182ed2d60cef 769 Gene3D G3DSA:3.50.50.60 418 489 1.2E-9 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFULGI_00013360 5e02a3e25d424e6e1b28182ed2d60cef 769 Pfam PF02662 Methyl-viologen-reducing hydrogenase, delta subunit 647 767 5.7E-49 T 01-11-2018 IPR003813 F420-non-reducing hydrogenase iron-sulfur subunit D GO:0055114 AFULGI_00013360 5e02a3e25d424e6e1b28182ed2d60cef 769 Gene3D G3DSA:3.30.70.20 596 637 1.6E-6 T 01-11-2018 AFULGI_00013360 5e02a3e25d424e6e1b28182ed2d60cef 769 Gene3D G3DSA:3.30.70.20 551 595 8.5E-7 T 01-11-2018 AFULGI_00013360 5e02a3e25d424e6e1b28182ed2d60cef 769 Pfam PF13187 4Fe-4S dicluster domain 575 619 8.9E-8 T 01-11-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFULGI_00013360 5e02a3e25d424e6e1b28182ed2d60cef 769 Gene3D G3DSA:3.40.50.720 137 232 3.4E-13 T 01-11-2018 AFULGI_00013360 5e02a3e25d424e6e1b28182ed2d60cef 769 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 604 615 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFULGI_00013360 5e02a3e25d424e6e1b28182ed2d60cef 769 Gene3D G3DSA:3.50.50.60 490 537 1.2E-9 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFULGI_00013360 5e02a3e25d424e6e1b28182ed2d60cef 769 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 142 543 6.7E-20 T 01-11-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFULGI_00013360 5e02a3e25d424e6e1b28182ed2d60cef 769 SUPERFAMILY SSF51905 140 554 1.23E-39 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFULGI_00013360 5e02a3e25d424e6e1b28182ed2d60cef 769 Gene3D G3DSA:3.30.70.20 236 338 3.8E-11 T 01-11-2018 AFULGI_00015180 9c6989bd965f4bfb0008f5d242646d0c 775 SUPERFAMILY SSF52540 73 292 3.6E-16 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00015180 9c6989bd965f4bfb0008f5d242646d0c 775 SMART SM00487 113 317 2.8E-8 T 01-11-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFULGI_00015180 9c6989bd965f4bfb0008f5d242646d0c 775 Gene3D G3DSA:3.40.50.300 119 305 4.3E-13 T 01-11-2018 AFULGI_00015180 9c6989bd965f4bfb0008f5d242646d0c 775 Pfam PF04851 Type III restriction enzyme, res subunit 126 278 8.7E-17 T 01-11-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 AFULGI_00011160 657bda08dffb502c8cbc53224612f7f3 165 Pfam PF01842 ACT domain 94 157 2.1E-8 T 01-11-2018 IPR002912 ACT domain AFULGI_00011160 657bda08dffb502c8cbc53224612f7f3 165 SUPERFAMILY SSF55021 103 163 3.72E-6 T 01-11-2018 AFULGI_00011160 657bda08dffb502c8cbc53224612f7f3 165 PIRSF PIRSF004897 1 165 1.3E-69 T 01-11-2018 IPR014424 Uncharacterised conserved protein UCP004897, ACT- type AFULGI_00026590 aba611ae6657cb6dce79340b516e5a35 175 Pfam PF02552 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit 3 172 1.5E-66 T 01-11-2018 IPR003704 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit GO:0019385 AFULGI_00026590 aba611ae6657cb6dce79340b516e5a35 175 TIGRFAM TIGR00315 cdhB: CO dehydrogenase/acetyl-CoA synthase complex, epsilon subunit 9 174 3.0E-76 T 01-11-2018 IPR003704 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit GO:0019385 AFULGI_00026590 aba611ae6657cb6dce79340b516e5a35 175 Hamap MF_01134 Acetyl-CoA decarbonylase/synthase complex subunit epsilon [cdhB]. 1 174 39.175 T 01-11-2018 IPR003704 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit GO:0019385 AFULGI_00026590 aba611ae6657cb6dce79340b516e5a35 175 PIRSF PIRSF006035 1 175 5.9E-76 T 01-11-2018 IPR003704 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit GO:0019385 AFULGI_00026590 aba611ae6657cb6dce79340b516e5a35 175 SUPERFAMILY SSF52467 20 173 2.49E-52 T 01-11-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily AFULGI_00026590 aba611ae6657cb6dce79340b516e5a35 175 Gene3D G3DSA:3.40.50.1220 18 175 1.4E-66 T 01-11-2018 AFULGI_00000330 19b070431edc7928a0dbe7c0cf843f16 299 Gene3D G3DSA:2.60.120.10 217 299 2.6E-56 T 01-11-2018 IPR014710 RmlC-like jelly roll fold AFULGI_00000330 19b070431edc7928a0dbe7c0cf843f16 299 PIRSF PIRSF036894 6 296 2.5E-32 T 01-11-2018 IPR014628 Mannose-6-phosphate isomerase, Firmicutes type, short form GO:0004476|GO:0005975 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 AFULGI_00000330 19b070431edc7928a0dbe7c0cf843f16 299 SUPERFAMILY SSF51182 4 293 1.0E-57 T 01-11-2018 IPR011051 RmlC-like cupin domain superfamily AFULGI_00000330 19b070431edc7928a0dbe7c0cf843f16 299 Gene3D G3DSA:2.60.120.10 1 216 1.4E-73 T 01-11-2018 IPR014710 RmlC-like jelly roll fold AFULGI_00000330 19b070431edc7928a0dbe7c0cf843f16 299 TIGRFAM TIGR00218 manA: mannose-6-phosphate isomerase, class I 104 294 5.0E-46 T 01-11-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 AFULGI_00000330 19b070431edc7928a0dbe7c0cf843f16 299 TIGRFAM TIGR00218 manA: mannose-6-phosphate isomerase, class I 4 106 1.9E-35 T 01-11-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 AFULGI_00000330 19b070431edc7928a0dbe7c0cf843f16 299 Pfam PF01238 Phosphomannose isomerase type I 34 111 1.6E-6 T 01-11-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 AFULGI_00020380 d49aea8ddd6c474ae038b59c657b1ea5 309 SMART SM00530 130 184 2.9E-10 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFULGI_00020380 d49aea8ddd6c474ae038b59c657b1ea5 309 SUPERFAMILY SSF47413 128 178 7.24E-11 T 01-11-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFULGI_00020380 d49aea8ddd6c474ae038b59c657b1ea5 309 Hamap MF_00584 Putative HTH-type transcriptional regulatory protein . 1 297 29.335 T 01-11-2018 IPR020886 Transcription regulator HTH, Cro/C1-type DNA-binding GO:0003700|GO:0006355 AFULGI_00020380 d49aea8ddd6c474ae038b59c657b1ea5 309 Gene3D G3DSA:1.10.260.40 123 190 5.0E-12 T 01-11-2018 AFULGI_00020380 d49aea8ddd6c474ae038b59c657b1ea5 309 Pfam PF01381 Helix-turn-helix 131 178 3.8E-11 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFULGI_00012900 4007b9ad5545bcb26cd94bfd5b1c985f 274 Hamap MF_01934 1,4-dihydroxy-2-naphthoyl-CoA synthase [menB]. 1 272 44.619 T 01-11-2018 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837 AFULGI_00012900 4007b9ad5545bcb26cd94bfd5b1c985f 274 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 111 131 - T 01-11-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 AFULGI_00012900 4007b9ad5545bcb26cd94bfd5b1c985f 274 Gene3D G3DSA:1.10.12.10 213 261 2.9E-23 T 01-11-2018 IPR014748 Enoyl-CoA hydratase, C-terminal AFULGI_00012900 4007b9ad5545bcb26cd94bfd5b1c985f 274 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 266 5.2E-62 T 01-11-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 AFULGI_00012900 4007b9ad5545bcb26cd94bfd5b1c985f 274 SUPERFAMILY SSF52096 3 266 3.11E-73 T 01-11-2018 IPR029045 ClpP/crotonase-like domain superfamily AFULGI_00012900 4007b9ad5545bcb26cd94bfd5b1c985f 274 Gene3D G3DSA:3.90.226.10 1 212 8.6E-64 T 01-11-2018 AFULGI_00002890 cbaf9cf21163a30f9649e5d8161cf4c9 108 Pfam PF01850 PIN domain 44 98 5.2E-5 T 01-11-2018 IPR002716 PIN domain AFULGI_00002890 cbaf9cf21163a30f9649e5d8161cf4c9 108 Gene3D G3DSA:3.40.50.1010 39 108 1.5E-10 T 01-11-2018 AFULGI_00002890 cbaf9cf21163a30f9649e5d8161cf4c9 108 SUPERFAMILY SSF88723 1 99 2.8E-15 T 01-11-2018 IPR029060 PIN-like domain superfamily AFULGI_00018550 b71bae42804cef7c0bad4778029c0fac 225 Pfam PF00218 Indole-3-glycerol phosphate synthase 4 219 1.5E-39 T 01-11-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 AFULGI_00018550 b71bae42804cef7c0bad4778029c0fac 225 Gene3D G3DSA:3.20.20.70 4 225 1.8E-52 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFULGI_00018550 b71bae42804cef7c0bad4778029c0fac 225 SUPERFAMILY SSF51366 3 221 5.79E-47 T 01-11-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 AFULGI_00017520 49d0f8a55b794ca6a24f714255877409 114 SUPERFAMILY SSF103196 1 110 4.32E-22 T 01-11-2018 AFULGI_00017520 49d0f8a55b794ca6a24f714255877409 114 Gene3D G3DSA:3.30.450.30 1 114 1.7E-19 T 01-11-2018 AFULGI_00017520 49d0f8a55b794ca6a24f714255877409 114 SMART SM00960 2 90 1.3E-15 T 01-11-2018 IPR004942 Roadblock/LAMTOR2 domain AFULGI_00017520 49d0f8a55b794ca6a24f714255877409 114 Pfam PF03259 Roadblock/LC7 domain 2 90 3.6E-19 T 01-11-2018 IPR004942 Roadblock/LAMTOR2 domain AFULGI_00024660 9ed11c595e0b2e9533ae33943e289bfb 180 Pfam PF08241 Methyltransferase domain 43 126 9.4E-12 T 01-11-2018 IPR013216 Methyltransferase type 11 GO:0008168 AFULGI_00024660 9ed11c595e0b2e9533ae33943e289bfb 180 SUPERFAMILY SSF53335 22 154 3.67E-23 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFULGI_00024660 9ed11c595e0b2e9533ae33943e289bfb 180 Gene3D G3DSA:3.40.50.150 1 178 2.3E-38 T 01-11-2018 AFULGI_00020110 6e515bc5041f3b5e0900ecc999927e5f 274 Gene3D G3DSA:3.40.50.620 1 145 5.3E-39 T 01-11-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFULGI_00020110 6e515bc5041f3b5e0900ecc999927e5f 274 PRINTS PR01438 Universal stress protein signature 150 168 1.0E-15 T 01-11-2018 IPR006015 Universal stress protein A AFULGI_00020110 6e515bc5041f3b5e0900ecc999927e5f 274 PRINTS PR01438 Universal stress protein signature 247 269 1.0E-15 T 01-11-2018 IPR006015 Universal stress protein A AFULGI_00020110 6e515bc5041f3b5e0900ecc999927e5f 274 PRINTS PR01438 Universal stress protein signature 229 241 1.0E-15 T 01-11-2018 IPR006015 Universal stress protein A AFULGI_00020110 6e515bc5041f3b5e0900ecc999927e5f 274 Pfam PF00582 Universal stress protein family 1 141 4.5E-17 T 01-11-2018 IPR006016 UspA AFULGI_00020110 6e515bc5041f3b5e0900ecc999927e5f 274 Pfam PF00582 Universal stress protein family 199 269 2.7E-15 T 01-11-2018 IPR006016 UspA AFULGI_00020110 6e515bc5041f3b5e0900ecc999927e5f 274 Pfam PF00582 Universal stress protein family 150 195 9.9E-7 T 01-11-2018 IPR006016 UspA AFULGI_00020110 6e515bc5041f3b5e0900ecc999927e5f 274 SUPERFAMILY SSF52402 150 272 7.96E-30 T 01-11-2018 AFULGI_00020110 6e515bc5041f3b5e0900ecc999927e5f 274 SUPERFAMILY SSF52402 3 143 4.19E-25 T 01-11-2018 AFULGI_00020110 6e515bc5041f3b5e0900ecc999927e5f 274 Gene3D G3DSA:3.40.50.620 146 274 7.4E-49 T 01-11-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFULGI_00026200 cef6c2e893a97f22e57ea9123a9eaa19 211 SMART SM01397 5 197 2.6E-107 T 01-11-2018 IPR001593 Ribosomal protein S3Ae GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00026200 cef6c2e893a97f22e57ea9123a9eaa19 211 Pfam PF01015 Ribosomal S3Ae family 7 197 8.1E-67 T 01-11-2018 IPR001593 Ribosomal protein S3Ae GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00026200 cef6c2e893a97f22e57ea9123a9eaa19 211 ProSitePatterns PS01191 Ribosomal protein S3Ae signature. 44 56 - T 01-11-2018 IPR018281 Ribosomal protein S3Ae, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00026200 cef6c2e893a97f22e57ea9123a9eaa19 211 Hamap MF_00359 30S ribosomal protein S3Ae [rps3ae]. 5 197 36.26 T 01-11-2018 IPR030838 30S ribosomal protein S3Ae GO:0003735|GO:0005840|GO:0006412 AFULGI_00005640 4a5dd59cb453f64a44a1175ab452c945 85 Gene3D G3DSA:3.30.110.40 12 84 9.9E-26 T 01-11-2018 IPR036868 TusA-like domain superfamily AFULGI_00005640 4a5dd59cb453f64a44a1175ab452c945 85 Pfam PF01206 Sulfurtransferase TusA 15 84 1.4E-24 T 01-11-2018 IPR001455 TusA-like domain AFULGI_00005640 4a5dd59cb453f64a44a1175ab452c945 85 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 16 40 - T 01-11-2018 IPR001455 TusA-like domain AFULGI_00005640 4a5dd59cb453f64a44a1175ab452c945 85 SUPERFAMILY SSF64307 8 84 6.93E-25 T 01-11-2018 IPR036868 TusA-like domain superfamily AFULGI_00000550 a6ccd47ff4bb770432fd71559ecb5c66 279 SUPERFAMILY SSF54631 120 278 7.96E-23 T 01-11-2018 AFULGI_00000550 a6ccd47ff4bb770432fd71559ecb5c66 279 SMART SM00116 68 115 2.2E-14 T 01-11-2018 IPR000644 CBS domain AFULGI_00000550 a6ccd47ff4bb770432fd71559ecb5c66 279 SMART SM00116 229 277 9.9E-5 T 01-11-2018 IPR000644 CBS domain AFULGI_00000550 a6ccd47ff4bb770432fd71559ecb5c66 279 SMART SM00116 10 57 7.8E-7 T 01-11-2018 IPR000644 CBS domain AFULGI_00000550 a6ccd47ff4bb770432fd71559ecb5c66 279 Gene3D G3DSA:3.10.580.10 1 122 8.0E-31 T 01-11-2018 AFULGI_00000550 a6ccd47ff4bb770432fd71559ecb5c66 279 Gene3D G3DSA:3.10.580.10 123 279 3.9E-20 T 01-11-2018 AFULGI_00000550 a6ccd47ff4bb770432fd71559ecb5c66 279 SUPERFAMILY SSF54631 1 117 1.04E-31 T 01-11-2018 AFULGI_00000550 a6ccd47ff4bb770432fd71559ecb5c66 279 Pfam PF00571 CBS domain 223 277 4.1E-10 T 01-11-2018 IPR000644 CBS domain AFULGI_00000550 a6ccd47ff4bb770432fd71559ecb5c66 279 Pfam PF00571 CBS domain 123 170 0.0022 T 01-11-2018 IPR000644 CBS domain AFULGI_00000550 a6ccd47ff4bb770432fd71559ecb5c66 279 Pfam PF00571 CBS domain 64 115 3.6E-15 T 01-11-2018 IPR000644 CBS domain AFULGI_00000550 a6ccd47ff4bb770432fd71559ecb5c66 279 Pfam PF00571 CBS domain 4 57 6.3E-12 T 01-11-2018 IPR000644 CBS domain AFULGI_00011300 3c0c93123867665d7d2e2a914303e83e 677 Gene3D G3DSA:3.30.450.20 22 160 1.9E-16 T 01-11-2018 AFULGI_00011300 3c0c93123867665d7d2e2a914303e83e 677 SUPERFAMILY SSF58104 315 431 2.09E-9 T 01-11-2018 AFULGI_00011300 3c0c93123867665d7d2e2a914303e83e 677 SMART SM00086 117 157 420.0 T 01-11-2018 IPR001610 PAC motif AFULGI_00011300 3c0c93123867665d7d2e2a914303e83e 677 SMART SM00086 242 283 0.0079 T 01-11-2018 IPR001610 PAC motif AFULGI_00011300 3c0c93123867665d7d2e2a914303e83e 677 SMART SM00283 376 637 5.5E-78 T 01-11-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AFULGI_00011300 3c0c93123867665d7d2e2a914303e83e 677 Gene3D G3DSA:3.30.450.20 161 293 2.1E-20 T 01-11-2018 AFULGI_00011300 3c0c93123867665d7d2e2a914303e83e 677 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 47 163 1.1E-10 T 01-11-2018 IPR000014 PAS domain AFULGI_00011300 3c0c93123867665d7d2e2a914303e83e 677 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 183 289 3.1E-12 T 01-11-2018 IPR000014 PAS domain AFULGI_00011300 3c0c93123867665d7d2e2a914303e83e 677 SMART SM00304 295 347 6.9E-10 T 01-11-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFULGI_00011300 3c0c93123867665d7d2e2a914303e83e 677 SMART SM00091 169 238 0.63 T 01-11-2018 IPR000014 PAS domain AFULGI_00011300 3c0c93123867665d7d2e2a914303e83e 677 SMART SM00091 35 105 0.27 T 01-11-2018 IPR000014 PAS domain AFULGI_00011300 3c0c93123867665d7d2e2a914303e83e 677 Gene3D G3DSA:1.10.287.950 325 652 9.9E-65 T 01-11-2018 AFULGI_00011300 3c0c93123867665d7d2e2a914303e83e 677 SUPERFAMILY SSF55785 22 155 1.92E-12 T 01-11-2018 IPR035965 PAS domain superfamily AFULGI_00011300 3c0c93123867665d7d2e2a914303e83e 677 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 448 603 1.6E-39 T 01-11-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AFULGI_00011300 3c0c93123867665d7d2e2a914303e83e 677 SUPERFAMILY SSF58104 409 641 5.36E-59 T 01-11-2018 AFULGI_00011300 3c0c93123867665d7d2e2a914303e83e 677 Pfam PF13426 PAS domain 184 282 5.2E-15 T 01-11-2018 IPR000014 PAS domain AFULGI_00011300 3c0c93123867665d7d2e2a914303e83e 677 Pfam PF13426 PAS domain 50 155 3.2E-9 T 01-11-2018 IPR000014 PAS domain AFULGI_00011300 3c0c93123867665d7d2e2a914303e83e 677 SUPERFAMILY SSF55785 154 281 3.49E-18 T 01-11-2018 IPR035965 PAS domain superfamily AFULGI_00008110 c6463963b5d05842b71e22f03081a1bc 293 Gene3D G3DSA:3.40.50.300 1 235 8.5E-66 T 01-11-2018 AFULGI_00008110 c6463963b5d05842b71e22f03081a1bc 293 SUPERFAMILY SSF52540 2 218 2.02E-60 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00008110 c6463963b5d05842b71e22f03081a1bc 293 Pfam PF00005 ABC transporter 17 165 2.3E-31 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFULGI_00008110 c6463963b5d05842b71e22f03081a1bc 293 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFULGI_00008110 c6463963b5d05842b71e22f03081a1bc 293 SMART SM00382 26 213 4.2E-9 T 01-11-2018 IPR003593 AAA+ ATPase domain AFULGI_00008110 c6463963b5d05842b71e22f03081a1bc 293 TIGRFAM TIGR01166 cbiO: cobalt ABC transporter, ATP-binding protein 13 199 8.7E-91 T 01-11-2018 IPR005876 Cobalt transport protein ATP-binding subunit GO:0006824 AFULGI_00015140 85d44a9a4418c351ae86f910c1ae66af 282 Pfam PF01032 FecCD transport family 4 279 6.6E-83 T 01-11-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 AFULGI_00015140 85d44a9a4418c351ae86f910c1ae66af 282 SUPERFAMILY SSF81345 5 280 4.58E-70 T 01-11-2018 IPR037294 ABC transporter, BtuC-like AFULGI_00015140 85d44a9a4418c351ae86f910c1ae66af 282 Gene3D G3DSA:1.10.3470.10 1 282 7.3E-89 T 01-11-2018 IPR037294 ABC transporter, BtuC-like AFULGI_00008610 941682d6d1c00ba57bc90214dc36dba1 309 Gene3D G3DSA:3.40.50.11030 214 309 1.4E-13 T 01-11-2018 IPR038385 Threonylcarbamoyl-AMP synthase, C-terminal domain superfamily AFULGI_00008610 941682d6d1c00ba57bc90214dc36dba1 309 PIRSF PIRSF004930 2 309 8.6E-95 T 01-11-2018 IPR010923 tRNA threonylcarbamoyladenosine biosynthesis protein SUA5 AFULGI_00008610 941682d6d1c00ba57bc90214dc36dba1 309 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 4 200 4.5E-78 T 01-11-2018 IPR006070 YrdC-like domain GO:0003725 AFULGI_00008610 941682d6d1c00ba57bc90214dc36dba1 309 SUPERFAMILY SSF55821 5 196 1.92E-60 T 01-11-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily AFULGI_00008610 941682d6d1c00ba57bc90214dc36dba1 309 Pfam PF01300 Telomere recombination 18 190 8.6E-55 T 01-11-2018 IPR006070 YrdC-like domain GO:0003725 AFULGI_00008610 941682d6d1c00ba57bc90214dc36dba1 309 Gene3D G3DSA:3.90.870.10 2 205 2.1E-69 T 01-11-2018 AFULGI_00008610 941682d6d1c00ba57bc90214dc36dba1 309 Pfam PF03481 Putative GTP-binding controlling metal-binding 209 302 5.8E-8 T 01-11-2018 IPR005145 Putative GTP-binding controlling metal-binding domain AFULGI_00015650 af32e1662b788bf41b6a7886d27caf9d 302 Pfam PF13353 4Fe-4S single cluster domain 18 166 1.4E-13 T 01-11-2018 AFULGI_00015650 af32e1662b788bf41b6a7886d27caf9d 302 Gene3D G3DSA:3.30.70.20 79 123 5.0E-6 T 01-11-2018 AFULGI_00015650 af32e1662b788bf41b6a7886d27caf9d 302 Gene3D G3DSA:3.80.30.10 124 300 4.5E-55 T 01-11-2018 AFULGI_00015650 af32e1662b788bf41b6a7886d27caf9d 302 SUPERFAMILY SSF54862 6 147 7.6E-24 T 01-11-2018 AFULGI_00015650 af32e1662b788bf41b6a7886d27caf9d 302 ProSitePatterns PS01087 Radical activating enzymes signature. 19 40 - T 01-11-2018 IPR001989 Radical-activating enzyme, conserved site GO:0016491|GO:0051539|GO:0055114 AFULGI_00015650 af32e1662b788bf41b6a7886d27caf9d 302 Gene3D G3DSA:3.20.20.70 4 78 1.5E-18 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFULGI_00015650 af32e1662b788bf41b6a7886d27caf9d 302 PIRSF PIRSF000371 1 300 3.3E-126 T 01-11-2018 IPR012839 Organic radical enzyme activase GO:0016491|GO:0055114 AFULGI_00015650 af32e1662b788bf41b6a7886d27caf9d 302 TIGRFAM TIGR02494 PFLE_PFLC: glycyl-radical enzyme activating protein 8 292 5.6E-118 T 01-11-2018 AFULGI_00015650 af32e1662b788bf41b6a7886d27caf9d 302 Pfam PF04055 Radical SAM superfamily 26 234 8.4E-31 T 01-11-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFULGI_00015650 af32e1662b788bf41b6a7886d27caf9d 302 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 85 96 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFULGI_00015650 af32e1662b788bf41b6a7886d27caf9d 302 SUPERFAMILY SSF102114 122 259 4.12E-19 T 01-11-2018 AFULGI_00002710 3e0bfc76d6548b5d198b5eff847a4de2 337 Hamap MF_01086 UPF0284 protein . 1 337 122.887 T 01-11-2018 IPR002805 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, putative AFULGI_00002710 3e0bfc76d6548b5d198b5eff847a4de2 337 SUPERFAMILY SSF52733 35 333 3.92E-52 T 01-11-2018 IPR036087 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like superfamily GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 AFULGI_00002710 3e0bfc76d6548b5d198b5eff847a4de2 337 Pfam PF02277 Phosphoribosyltransferase 93 243 2.3E-12 T 01-11-2018 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 AFULGI_00002710 3e0bfc76d6548b5d198b5eff847a4de2 337 TIGRFAM TIGR00303 TIGR00303: TIGR00303 family protein 13 329 1.1E-147 T 01-11-2018 IPR002805 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, putative AFULGI_00002710 3e0bfc76d6548b5d198b5eff847a4de2 337 Gene3D G3DSA:3.40.50.10210 15 337 7.9E-115 T 01-11-2018 AFULGI_00003270 bed7387d59737eac685c508ae29f9e80 348 SUPERFAMILY SSF53448 6 215 7.24E-34 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFULGI_00003270 bed7387d59737eac685c508ae29f9e80 348 Gene3D G3DSA:3.90.550.10 2 195 7.8E-39 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFULGI_00003270 bed7387d59737eac685c508ae29f9e80 348 Pfam PF00535 Glycosyl transferase family 2 5 135 3.8E-26 T 01-11-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 AFULGI_00005190 6a8b3c2815e5be81316bf5ae0c5e7d54 198 SUPERFAMILY SSF52317 2 194 1.32E-48 T 01-11-2018 IPR029062 Class I glutamine amidotransferase-like AFULGI_00005190 6a8b3c2815e5be81316bf5ae0c5e7d54 198 TIGRFAM TIGR03800 PLP_synth_Pdx2: pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2 2 193 1.9E-62 T 01-11-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 AFULGI_00005190 6a8b3c2815e5be81316bf5ae0c5e7d54 198 Gene3D G3DSA:3.40.50.880 1 198 2.8E-62 T 01-11-2018 IPR029062 Class I glutamine amidotransferase-like AFULGI_00005190 6a8b3c2815e5be81316bf5ae0c5e7d54 198 Hamap MF_01615 Pyridoxal 5'-phosphate synthase subunit PdxT [pdxT]. 3 194 35.459 T 01-11-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 AFULGI_00005190 6a8b3c2815e5be81316bf5ae0c5e7d54 198 PIRSF PIRSF005639 1 198 5.5E-70 T 01-11-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 AFULGI_00005190 6a8b3c2815e5be81316bf5ae0c5e7d54 198 Pfam PF01174 SNO glutamine amidotransferase family 5 193 1.1E-50 T 01-11-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 AFULGI_00005190 6a8b3c2815e5be81316bf5ae0c5e7d54 198 ProSitePatterns PS01236 PdxT/SNO family family signature. 46 56 - T 01-11-2018 IPR021196 PdxT/SNO family, conserved site KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 AFULGI_00013450 f67e79a7b7b489c7380fd1bf2f6e5256 424 SMART SM00729 133 351 1.1E-59 T 01-11-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 AFULGI_00013450 f67e79a7b7b489c7380fd1bf2f6e5256 424 Gene3D G3DSA:3.40.50.12160 1 122 7.7E-18 T 01-11-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily AFULGI_00013450 f67e79a7b7b489c7380fd1bf2f6e5256 424 SUPERFAMILY SSF102114 129 359 5.1E-51 T 01-11-2018 AFULGI_00013450 f67e79a7b7b489c7380fd1bf2f6e5256 424 Pfam PF00919 Uncharacterized protein family UPF0004 2 84 2.1E-17 T 01-11-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 AFULGI_00013450 f67e79a7b7b489c7380fd1bf2f6e5256 424 Pfam PF01938 TRAM domain 362 418 4.8E-14 T 01-11-2018 IPR002792 TRAM domain AFULGI_00013450 f67e79a7b7b489c7380fd1bf2f6e5256 424 Pfam PF04055 Radical SAM superfamily 137 310 1.3E-25 T 01-11-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFULGI_00013450 f67e79a7b7b489c7380fd1bf2f6e5256 424 Gene3D G3DSA:3.80.30.20 131 365 1.1E-79 T 01-11-2018 IPR023404 Radical SAM, alpha/beta horseshoe AFULGI_00013450 f67e79a7b7b489c7380fd1bf2f6e5256 424 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 2 416 4.5E-122 T 01-11-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 AFULGI_00013450 f67e79a7b7b489c7380fd1bf2f6e5256 424 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 137 157 - T 01-11-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 AFULGI_00013450 f67e79a7b7b489c7380fd1bf2f6e5256 424 TIGRFAM TIGR01578 MiaB-like-B: MiaB-like tRNA modifying enzyme, archaeal-type 2 418 6.9E-136 T 01-11-2018 IPR006466 MiaB-like tRNA modifying enzyme, archaeal-type Reactome: R-HSA-6782315 AFULGI_00003990 b41e041c124f3936f9df4a2aa9ddca6d 260 PIRSF PIRSF006692 1 249 1.3E-67 T 01-11-2018 IPR016490 Transcriptional regulator, HTH, AF0396-type AFULGI_00003990 b41e041c124f3936f9df4a2aa9ddca6d 260 Gene3D G3DSA:1.10.10.10 4 77 5.7E-9 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00003990 b41e041c124f3936f9df4a2aa9ddca6d 260 SUPERFAMILY SSF46785 6 155 6.09E-14 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00003990 b41e041c124f3936f9df4a2aa9ddca6d 260 Pfam PF01022 Bacterial regulatory protein, arsR family 6 50 3.7E-13 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFULGI_00003990 b41e041c124f3936f9df4a2aa9ddca6d 260 Pfam PF08350 Domain of unknown function (DUF1724) 188 240 2.4E-10 T 01-11-2018 IPR013561 Domain of unknown function DUF1724 AFULGI_00017570 77a9439b8924bd9d41b840e11e73bedd 386 SUPERFAMILY SSF161093 11 183 2.35E-29 T 01-11-2018 IPR036739 SLC41 divalent cation transporters, integral membrane domain superfamily GO:0006812|GO:0008324 AFULGI_00017570 77a9439b8924bd9d41b840e11e73bedd 386 Pfam PF01769 Divalent cation transporter 256 379 3.4E-18 T 01-11-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 AFULGI_00017570 77a9439b8924bd9d41b840e11e73bedd 386 Pfam PF01769 Divalent cation transporter 52 176 3.8E-20 T 01-11-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 AFULGI_00017570 77a9439b8924bd9d41b840e11e73bedd 386 SUPERFAMILY SSF161093 215 385 1.83E-26 T 01-11-2018 IPR036739 SLC41 divalent cation transporters, integral membrane domain superfamily GO:0006812|GO:0008324 AFULGI_00017570 77a9439b8924bd9d41b840e11e73bedd 386 Gene3D G3DSA:1.10.357.20 214 386 2.9E-15 T 01-11-2018 IPR038048 Magnesium transporter MgtE, transmembrane domain AFULGI_00017570 77a9439b8924bd9d41b840e11e73bedd 386 Gene3D G3DSA:1.10.357.20 5 183 7.3E-7 T 01-11-2018 IPR038048 Magnesium transporter MgtE, transmembrane domain AFULGI_00000300 d709aa2c288041b138fa61dfe88a1cae 180 SMART SM00471 12 120 2.7E-5 T 01-11-2018 IPR003607 HD/PDEase domain AFULGI_00000300 d709aa2c288041b138fa61dfe88a1cae 180 TIGRFAM TIGR00277 HDIG: HDIG domain 13 88 4.4E-21 T 01-11-2018 IPR006675 HDIG domain AFULGI_00000300 d709aa2c288041b138fa61dfe88a1cae 180 Pfam PF01966 HD domain 17 107 4.0E-13 T 01-11-2018 IPR006674 HD domain AFULGI_00000300 d709aa2c288041b138fa61dfe88a1cae 180 SUPERFAMILY SSF109604 5 152 1.41E-17 T 01-11-2018 AFULGI_00000300 d709aa2c288041b138fa61dfe88a1cae 180 Gene3D G3DSA:1.10.3210.10 2 139 6.3E-13 T 01-11-2018 AFULGI_00020930 d4828dd5c16a7349c74915476950f6d6 256 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 3 255 1.6E-93 T 01-11-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 AFULGI_00020930 d4828dd5c16a7349c74915476950f6d6 256 Gene3D G3DSA:3.40.50.10800 127 211 6.9E-93 T 01-11-2018 AFULGI_00020930 d4828dd5c16a7349c74915476950f6d6 256 SUPERFAMILY SSF142754 2 255 2.48E-85 T 01-11-2018 IPR036094 Quinolinate synthetase A superfamily GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 AFULGI_00020930 d4828dd5c16a7349c74915476950f6d6 256 Gene3D G3DSA:3.40.50.10800 43 254 6.9E-93 T 01-11-2018 AFULGI_00020930 d4828dd5c16a7349c74915476950f6d6 256 Pfam PF02445 Quinolinate synthetase A protein 2 254 1.5E-89 T 01-11-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 AFULGI_00020930 d4828dd5c16a7349c74915476950f6d6 256 Gene3D G3DSA:3.40.50.10800 2 236 6.9E-93 T 01-11-2018 AFULGI_00019750 0565e3805a5cc08cf596b2ea861bb145 305 Pfam PF03747 ADP-ribosylglycohydrolase 8 269 1.0E-69 T 01-11-2018 IPR005502 ADP-ribosylation/Crystallin J1 AFULGI_00019750 0565e3805a5cc08cf596b2ea861bb145 305 Gene3D G3DSA:1.10.4080.10 1 303 7.8E-88 T 01-11-2018 IPR036705 ADP-ribosylation/Crystallin J1 superfamily AFULGI_00019750 0565e3805a5cc08cf596b2ea861bb145 305 SUPERFAMILY SSF101478 2 298 8.89E-81 T 01-11-2018 IPR036705 ADP-ribosylation/Crystallin J1 superfamily AFULGI_00019600 e2b239732c7fa1c071ba47fa389d4f1f 274 SUPERFAMILY SSF116734 2 63 9.32E-15 T 01-11-2018 AFULGI_00019600 e2b239732c7fa1c071ba47fa389d4f1f 274 Gene3D G3DSA:3.90.220.20 59 219 4.7E-36 T 01-11-2018 AFULGI_00019600 e2b239732c7fa1c071ba47fa389d4f1f 274 Pfam PF01420 Type I restriction modification DNA specificity domain 73 252 1.9E-40 T 01-11-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 AFULGI_00019600 e2b239732c7fa1c071ba47fa389d4f1f 274 Pfam PF01420 Type I restriction modification DNA specificity domain 3 35 3.0E-5 T 01-11-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 AFULGI_00019600 e2b239732c7fa1c071ba47fa389d4f1f 274 Gene3D G3DSA:1.10.287.1120 220 274 6.2E-15 T 01-11-2018 AFULGI_00019600 e2b239732c7fa1c071ba47fa389d4f1f 274 Gene3D G3DSA:3.90.220.20 1 58 1.5E-10 T 01-11-2018 AFULGI_00019600 e2b239732c7fa1c071ba47fa389d4f1f 274 SUPERFAMILY SSF116734 62 269 1.49E-53 T 01-11-2018 AFULGI_00019110 51962f602d1b050bcd8e4698786f303c 70 SUPERFAMILY SSF46785 7 54 2.49E-9 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00019110 51962f602d1b050bcd8e4698786f303c 70 Gene3D G3DSA:1.10.10.10 5 67 5.2E-7 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00019110 51962f602d1b050bcd8e4698786f303c 70 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 13 51 1.0E-6 T 01-11-2018 IPR002831 Transcription regulator TrmB, N-terminal AFULGI_00010490 5a9b2aeda8f939d0ab82cd9c6ef1dd27 212 SMART SM00382 24 211 1.0E-10 T 01-11-2018 IPR003593 AAA+ ATPase domain AFULGI_00010490 5a9b2aeda8f939d0ab82cd9c6ef1dd27 212 ProSitePatterns PS00211 ABC transporters family signature. 132 146 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFULGI_00010490 5a9b2aeda8f939d0ab82cd9c6ef1dd27 212 Gene3D G3DSA:3.40.50.300 1 212 5.7E-59 T 01-11-2018 AFULGI_00010490 5a9b2aeda8f939d0ab82cd9c6ef1dd27 212 Pfam PF00005 ABC transporter 25 159 4.4E-30 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFULGI_00010490 5a9b2aeda8f939d0ab82cd9c6ef1dd27 212 SUPERFAMILY SSF52540 2 210 6.44E-58 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00006700 f0d7e4867c46697e7261ff538e296b18 482 Pfam PF01943 Polysaccharide biosynthesis protein 6 284 2.1E-69 T 01-11-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 AFULGI_00006700 f0d7e4867c46697e7261ff538e296b18 482 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 335 465 7.5E-18 T 01-11-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain AFULGI_00001100 578d0f2409721b309209e01337456ff9 356 Pfam PF06849 Protein of unknown function (DUF1246) 19 138 6.7E-46 T 01-11-2018 IPR010672 IMP biosynthesis enzyme PurP, N-terminal GO:0000287|GO:0005524|GO:0006188|GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 AFULGI_00001100 578d0f2409721b309209e01337456ff9 356 Pfam PF06973 Domain of unknown function (DUF1297) 169 355 7.8E-76 T 01-11-2018 IPR009720 IMP biosynthesis enzyme PurP, C-terminal GO:0000287|GO:0005524|GO:0006188|GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 AFULGI_00001100 578d0f2409721b309209e01337456ff9 356 Gene3D G3DSA:3.40.50.20 1 104 3.7E-37 T 01-11-2018 AFULGI_00001100 578d0f2409721b309209e01337456ff9 356 Gene3D G3DSA:3.30.1490.20 135 198 1.2E-97 T 01-11-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 AFULGI_00001100 578d0f2409721b309209e01337456ff9 356 Hamap MF_01163 5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase [purP]. 17 356 52.576 T 01-11-2018 IPR023656 IMP biosynthesis enzyme PurP GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 AFULGI_00001100 578d0f2409721b309209e01337456ff9 356 Gene3D G3DSA:3.30.470.20 107 355 1.2E-97 T 01-11-2018 AFULGI_00001100 578d0f2409721b309209e01337456ff9 356 SUPERFAMILY SSF56059 122 355 2.95E-77 T 01-11-2018 AFULGI_00001100 578d0f2409721b309209e01337456ff9 356 PIRSF PIRSF004602 1 356 5.0E-154 T 01-11-2018 IPR023656 IMP biosynthesis enzyme PurP GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 AFULGI_00001100 578d0f2409721b309209e01337456ff9 356 SUPERFAMILY SSF52440 2 117 2.11E-41 T 01-11-2018 IPR016185 Pre-ATP-grasp domain superfamily AFULGI_00004820 33f515ba36d04cd7189a692139e36c36 180 Pfam PF08394 Archaeal TRASH domain 141 176 7.4E-19 T 01-11-2018 IPR013603 TRASH transcription regulator C-terminal, archaeal AFULGI_00004820 33f515ba36d04cd7189a692139e36c36 180 SUPERFAMILY SSF46785 2 56 2.26E-14 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00004820 33f515ba36d04cd7189a692139e36c36 180 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 19 30 2.1E-14 T 01-11-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFULGI_00004820 33f515ba36d04cd7189a692139e36c36 180 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 30 49 2.1E-14 T 01-11-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFULGI_00004820 33f515ba36d04cd7189a692139e36c36 180 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 3 19 2.1E-14 T 01-11-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFULGI_00004820 33f515ba36d04cd7189a692139e36c36 180 ProSitePatterns PS00519 AsnC-type HTH domain signature. 21 47 - T 01-11-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site AFULGI_00004820 33f515ba36d04cd7189a692139e36c36 180 SMART SM00746 141 177 6.2E-8 T 01-11-2018 IPR011017 TRASH domain AFULGI_00004820 33f515ba36d04cd7189a692139e36c36 180 Gene3D G3DSA:1.10.10.10 1 54 4.7E-22 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00004820 33f515ba36d04cd7189a692139e36c36 180 Pfam PF13412 Winged helix-turn-helix DNA-binding 3 50 3.7E-17 T 01-11-2018 AFULGI_00004820 33f515ba36d04cd7189a692139e36c36 180 SMART SM00344 3 110 9.3E-31 T 01-11-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 AFULGI_00001940 3affc5cdfa9ca8b1a3dce698bf0deba2 495 Pfam PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain 279 335 1.1E-16 T 01-11-2018 IPR039506 SpoOB, alpha-helical domain AFULGI_00001940 3affc5cdfa9ca8b1a3dce698bf0deba2 495 Gene3D G3DSA:1.10.287.130 269 338 4.4E-8 T 01-11-2018 AFULGI_00001940 3affc5cdfa9ca8b1a3dce698bf0deba2 495 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 387 487 5.2E-22 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFULGI_00001940 3affc5cdfa9ca8b1a3dce698bf0deba2 495 SMART SM00387 383 489 2.8E-30 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFULGI_00001940 3affc5cdfa9ca8b1a3dce698bf0deba2 495 SUPERFAMILY SSF55874 353 485 3.14E-30 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFULGI_00001940 3affc5cdfa9ca8b1a3dce698bf0deba2 495 Gene3D G3DSA:3.30.565.10 339 493 6.0E-31 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFULGI_00001940 3affc5cdfa9ca8b1a3dce698bf0deba2 495 PRINTS PR00344 Bacterial sensor protein C-terminal signature 419 433 6.0E-11 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFULGI_00001940 3affc5cdfa9ca8b1a3dce698bf0deba2 495 PRINTS PR00344 Bacterial sensor protein C-terminal signature 449 467 6.0E-11 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFULGI_00001940 3affc5cdfa9ca8b1a3dce698bf0deba2 495 PRINTS PR00344 Bacterial sensor protein C-terminal signature 473 486 6.0E-11 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFULGI_00001940 3affc5cdfa9ca8b1a3dce698bf0deba2 495 SUPERFAMILY SSF55890 294 334 7.98E-7 T 01-11-2018 IPR016120 Signal transduction histidine kinase, sporulation regulator SpoOB GO:0000155|GO:0000160|GO:0016772 AFULGI_00000400 72d48a5ca735713abc99f8229adec60f 303 Pfam PF17231 Family of unknown function (DUF5305) 123 292 3.5E-12 T 01-11-2018 IPR035185 Protein of unknown function DUF5305 AFULGI_00017190 4874e572e850f643148102f2d3176cf3 40 SUPERFAMILY SSF55874 1 35 1.07E-8 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFULGI_00017190 4874e572e850f643148102f2d3176cf3 40 Gene3D G3DSA:3.30.565.10 1 35 5.5E-8 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFULGI_00013940 809c7dcffa5ca9cb7e2de8fc51f40116 352 ProSitePatterns PS00674 AAA-protein family signature. 239 258 - T 01-11-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 AFULGI_00013940 809c7dcffa5ca9cb7e2de8fc51f40116 352 SUPERFAMILY SSF52540 96 338 9.81E-58 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00013940 809c7dcffa5ca9cb7e2de8fc51f40116 352 SMART SM00382 134 269 2.1E-18 T 01-11-2018 IPR003593 AAA+ ATPase domain AFULGI_00013940 809c7dcffa5ca9cb7e2de8fc51f40116 352 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 138 266 4.0E-37 T 01-11-2018 IPR003959 ATPase, AAA-type, core GO:0005524 AFULGI_00013940 809c7dcffa5ca9cb7e2de8fc51f40116 352 Gene3D G3DSA:1.10.8.60 269 349 8.6E-11 T 01-11-2018 AFULGI_00013940 809c7dcffa5ca9cb7e2de8fc51f40116 352 Gene3D G3DSA:3.40.50.300 93 268 3.1E-50 T 01-11-2018 AFULGI_00021650 bc6b49388bbd17790ac3f0c85ea402c2 189 SUPERFAMILY SSF53137 4 185 5.76E-61 T 01-11-2018 AFULGI_00021650 bc6b49388bbd17790ac3f0c85ea402c2 189 Hamap MF_01337_A 50S ribosomal protein L18 [rplR]. 7 185 43.474 T 01-11-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00021650 bc6b49388bbd17790ac3f0c85ea402c2 189 Pfam PF17144 Ribosomal large subunit proteins 60S L5, and 50S L18 102 135 2.7E-9 T 01-11-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00021650 bc6b49388bbd17790ac3f0c85ea402c2 189 Pfam PF17144 Ribosomal large subunit proteins 60S L5, and 50S L18 8 98 4.0E-23 T 01-11-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00021650 bc6b49388bbd17790ac3f0c85ea402c2 189 Gene3D G3DSA:3.30.420.100 3 188 1.7E-69 T 01-11-2018 AFULGI_00022640 c1d5529db0766d2dc455b8756a27ee14 405 SMART SM00997 173 333 2.6E-109 T 01-11-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 AFULGI_00022640 c1d5529db0766d2dc455b8756a27ee14 405 Hamap MF_00563 Adenosylhomocysteinase [ahcY]. 1 405 47.753 T 01-11-2018 IPR034373 Adenosylhomocysteinase GO:0004013|GO:0019510|GO:0051287 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-2408508|Reactome: R-HSA-5578997 AFULGI_00022640 c1d5529db0766d2dc455b8756a27ee14 405 SMART SM00996 3 402 7.7E-132 T 01-11-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 AFULGI_00022640 c1d5529db0766d2dc455b8756a27ee14 405 ProSitePatterns PS00738 S-adenosyl-L-homocysteine hydrolase signature 1. 63 77 - T 01-11-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 AFULGI_00022640 c1d5529db0766d2dc455b8756a27ee14 405 Gene3D G3DSA:3.40.50.1480 2 394 1.0E-174 T 01-11-2018 AFULGI_00022640 c1d5529db0766d2dc455b8756a27ee14 405 Gene3D G3DSA:3.40.50.720 175 333 1.0E-174 T 01-11-2018 AFULGI_00022640 c1d5529db0766d2dc455b8756a27ee14 405 TIGRFAM TIGR00936 ahcY: adenosylhomocysteinase 2 405 2.0E-208 T 01-11-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 AFULGI_00022640 c1d5529db0766d2dc455b8756a27ee14 405 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 195 211 - T 01-11-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 AFULGI_00022640 c1d5529db0766d2dc455b8756a27ee14 405 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 173 332 3.1E-53 T 01-11-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 AFULGI_00022640 c1d5529db0766d2dc455b8756a27ee14 405 SUPERFAMILY SSF51735 173 334 4.16E-66 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily AFULGI_00022640 c1d5529db0766d2dc455b8756a27ee14 405 SUPERFAMILY SSF52283 3 405 3.0E-97 T 01-11-2018 AFULGI_00022640 c1d5529db0766d2dc455b8756a27ee14 405 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 126 398 3.1E-31 T 01-11-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 AFULGI_00022640 c1d5529db0766d2dc455b8756a27ee14 405 PIRSF PIRSF001109 1 405 9.5E-189 T 01-11-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 AFULGI_00002720 37439d19face3ea4c0fedeccd70ec9e4 626 SUPERFAMILY SSF55785 189 291 8.05E-14 T 01-11-2018 IPR035965 PAS domain superfamily AFULGI_00002720 37439d19face3ea4c0fedeccd70ec9e4 626 SMART SM00091 291 357 8.8E-9 T 01-11-2018 IPR000014 PAS domain AFULGI_00002720 37439d19face3ea4c0fedeccd70ec9e4 626 SMART SM00091 168 236 0.04 T 01-11-2018 IPR000014 PAS domain AFULGI_00002720 37439d19face3ea4c0fedeccd70ec9e4 626 SMART SM00091 69 131 37.0 T 01-11-2018 IPR000014 PAS domain AFULGI_00002720 37439d19face3ea4c0fedeccd70ec9e4 626 Gene3D G3DSA:3.30.450.20 175 294 8.7E-13 T 01-11-2018 AFULGI_00002720 37439d19face3ea4c0fedeccd70ec9e4 626 SUPERFAMILY SSF55781 397 538 7.63E-8 T 01-11-2018 AFULGI_00002720 37439d19face3ea4c0fedeccd70ec9e4 626 Gene3D G3DSA:3.30.450.20 295 416 4.4E-26 T 01-11-2018 AFULGI_00002720 37439d19face3ea4c0fedeccd70ec9e4 626 SMART SM00388 557 618 1.7E-5 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFULGI_00002720 37439d19face3ea4c0fedeccd70ec9e4 626 Pfam PF13188 PAS domain 76 106 0.045 T 01-11-2018 IPR000014 PAS domain AFULGI_00002720 37439d19face3ea4c0fedeccd70ec9e4 626 Pfam PF08448 PAS fold 298 404 1.2E-14 T 01-11-2018 IPR013656 PAS fold-4 AFULGI_00002720 37439d19face3ea4c0fedeccd70ec9e4 626 Pfam PF08447 PAS fold 203 262 1.4E-6 T 01-11-2018 IPR013655 PAS fold-3 GO:0005515 AFULGI_00002720 37439d19face3ea4c0fedeccd70ec9e4 626 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 287 410 2.6E-32 T 01-11-2018 IPR000014 PAS domain AFULGI_00002720 37439d19face3ea4c0fedeccd70ec9e4 626 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 183 290 8.9E-14 T 01-11-2018 IPR000014 PAS domain AFULGI_00002720 37439d19face3ea4c0fedeccd70ec9e4 626 SMART SM00086 362 403 1.5 T 01-11-2018 IPR001610 PAC motif AFULGI_00002720 37439d19face3ea4c0fedeccd70ec9e4 626 SMART SM00086 243 283 15.0 T 01-11-2018 IPR001610 PAC motif AFULGI_00002720 37439d19face3ea4c0fedeccd70ec9e4 626 SUPERFAMILY SSF55785 302 412 1.4E-23 T 01-11-2018 IPR035965 PAS domain superfamily AFULGI_00002290 498c4331038e20d98f8f5332fa78dce2 529 Pfam PF04055 Radical SAM superfamily 165 357 4.8E-13 T 01-11-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFULGI_00002290 498c4331038e20d98f8f5332fa78dce2 529 Gene3D G3DSA:3.80.30.20 162 410 1.8E-18 T 01-11-2018 IPR023404 Radical SAM, alpha/beta horseshoe AFULGI_00002290 498c4331038e20d98f8f5332fa78dce2 529 SUPERFAMILY SSF102114 161 389 1.96E-18 T 01-11-2018 AFULGI_00002290 498c4331038e20d98f8f5332fa78dce2 529 SMART SM00729 161 400 7.5E-23 T 01-11-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 AFULGI_00004700 bb7f781846bb7c586f082e46f4fdfe27 62 Pfam PF14697 4Fe-4S dicluster domain 5 58 1.6E-10 T 01-11-2018 AFULGI_00004700 bb7f781846bb7c586f082e46f4fdfe27 62 Gene3D G3DSA:3.30.70.20 1 31 2.1E-6 T 01-11-2018 AFULGI_00004700 bb7f781846bb7c586f082e46f4fdfe27 62 Gene3D G3DSA:3.30.70.20 32 61 3.8E-8 T 01-11-2018 AFULGI_00004700 bb7f781846bb7c586f082e46f4fdfe27 62 SUPERFAMILY SSF54862 4 61 3.26E-19 T 01-11-2018 AFULGI_00004700 bb7f781846bb7c586f082e46f4fdfe27 62 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 41 52 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFULGI_00014250 6a210240efc6470d46317d530e586f3f 331 SUPERFAMILY SSF89796 1 330 7.46E-88 T 01-11-2018 IPR023606 CoA-transferase family III domain superfamily AFULGI_00014250 6a210240efc6470d46317d530e586f3f 331 Gene3D G3DSA:3.30.1540.10 209 295 1.8E-85 T 01-11-2018 AFULGI_00014250 6a210240efc6470d46317d530e586f3f 331 Gene3D G3DSA:3.40.50.10540 2 301 1.8E-85 T 01-11-2018 IPR023606 CoA-transferase family III domain superfamily AFULGI_00014250 6a210240efc6470d46317d530e586f3f 331 Pfam PF02515 CoA-transferase family III 2 330 2.5E-75 T 01-11-2018 IPR003673 CoA-transferase family III GO:0003824 AFULGI_00020460 bbc8778735b01d7b2b0a03fa5efa53c0 344 Gene3D G3DSA:2.40.30.40 64 155 1.9E-132 T 01-11-2018 IPR023367 Peptidase M42, domain 2 AFULGI_00020460 bbc8778735b01d7b2b0a03fa5efa53c0 344 SUPERFAMILY SSF53187 2 340 2.77E-67 T 01-11-2018 AFULGI_00020460 bbc8778735b01d7b2b0a03fa5efa53c0 344 PIRSF PIRSF001123 1 344 1.5E-127 T 01-11-2018 IPR008007 Peptidase M42 AFULGI_00020460 bbc8778735b01d7b2b0a03fa5efa53c0 344 SUPERFAMILY SSF101821 65 172 9.77E-33 T 01-11-2018 AFULGI_00020460 bbc8778735b01d7b2b0a03fa5efa53c0 344 Gene3D G3DSA:3.40.630.10 4 332 1.9E-132 T 01-11-2018 AFULGI_00020460 bbc8778735b01d7b2b0a03fa5efa53c0 344 Pfam PF05343 M42 glutamyl aminopeptidase 42 331 9.6E-111 T 01-11-2018 IPR008007 Peptidase M42 AFULGI_00020340 5d2081d7f78c4f970cdf80648182044c 234 SUPERFAMILY SSF53335 2 230 2.2E-56 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFULGI_00020340 5d2081d7f78c4f970cdf80648182044c 234 Pfam PF00398 Ribosomal RNA adenine dimethylase 2 198 1.3E-42 T 01-11-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm AFULGI_00020340 5d2081d7f78c4f970cdf80648182044c 234 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 23 49 - T 01-11-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 AFULGI_00020340 5d2081d7f78c4f970cdf80648182044c 234 Gene3D G3DSA:3.40.50.150 1 169 8.3E-52 T 01-11-2018 AFULGI_00020340 5d2081d7f78c4f970cdf80648182044c 234 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 1 231 1.0E-68 T 01-11-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 AFULGI_00020340 5d2081d7f78c4f970cdf80648182044c 234 SMART SM00650 7 168 4.2E-76 T 01-11-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 AFULGI_00020340 5d2081d7f78c4f970cdf80648182044c 234 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 2 233 41.213 T 01-11-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 AFULGI_00026790 0d9291763bcd7f83e19dc1956d70f6d2 229 SUPERFAMILY SSF47413 18 70 2.23E-12 T 01-11-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFULGI_00026790 0d9291763bcd7f83e19dc1956d70f6d2 229 Pfam PF01381 Helix-turn-helix 34 71 2.2E-9 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFULGI_00026790 0d9291763bcd7f83e19dc1956d70f6d2 229 PIRSF PIRSF037724 1 229 8.1E-101 T 01-11-2018 IPR017271 Transcription regulator HTH, MJ1545, predicted AFULGI_00026790 0d9291763bcd7f83e19dc1956d70f6d2 229 Gene3D G3DSA:1.10.260.40 16 74 3.0E-11 T 01-11-2018 AFULGI_00026790 0d9291763bcd7f83e19dc1956d70f6d2 229 SMART SM00530 23 77 7.1E-11 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFULGI_00004140 94a89cc93b2f88a24d848ee1a98c5034 386 Pfam PF00155 Aminotransferase class I and II 32 380 4.1E-63 T 01-11-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 AFULGI_00004140 94a89cc93b2f88a24d848ee1a98c5034 386 TIGRFAM TIGR03540 DapC_direct: LL-diaminopimelate aminotransferase 3 382 3.6E-195 T 01-11-2018 IPR019881 Diaminopimelate aminotransferase, DapL, Desulfovibrio-type GO:0009089|GO:0010285 KEGG: 00300+2.6.1.83|MetaCyc: PWY-5097 AFULGI_00004140 94a89cc93b2f88a24d848ee1a98c5034 386 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 236 249 - T 01-11-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 AFULGI_00004140 94a89cc93b2f88a24d848ee1a98c5034 386 SUPERFAMILY SSF53383 1 385 2.89E-112 T 01-11-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFULGI_00004140 94a89cc93b2f88a24d848ee1a98c5034 386 Gene3D G3DSA:3.90.1150.10 18 380 3.0E-130 T 01-11-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFULGI_00004140 94a89cc93b2f88a24d848ee1a98c5034 386 Gene3D G3DSA:3.40.640.10 43 284 3.0E-130 T 01-11-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFULGI_00021870 a1c316350f7ee45171938d59399f4058 122 SUPERFAMILY SSF50692 7 115 2.68E-21 T 01-11-2018 IPR009010 Aspartate decarboxylase-like domain superfamily AFULGI_00021870 a1c316350f7ee45171938d59399f4058 122 Gene3D G3DSA:2.40.40.20 1 122 9.2E-53 T 01-11-2018 AFULGI_00021870 a1c316350f7ee45171938d59399f4058 122 Pfam PF01568 Molydopterin dinucleotide binding domain 6 101 2.6E-19 T 01-11-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 AFULGI_00021870 a1c316350f7ee45171938d59399f4058 122 PIRSF PIRSF015873 2 122 5.6E-53 T 01-11-2018 IPR012040 Formylmethanofuran dehydrogenase, subunit D AFULGI_00021040 d0fafe8095e3adca5d98eff1ac178ad1 291 SUPERFAMILY SSF56281 1 266 2.17E-50 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFULGI_00021040 d0fafe8095e3adca5d98eff1ac178ad1 291 SMART SM00849 21 210 1.6E-38 T 01-11-2018 IPR001279 Metallo-beta-lactamase AFULGI_00021040 d0fafe8095e3adca5d98eff1ac178ad1 291 Pfam PF00753 Metallo-beta-lactamase superfamily 19 210 1.3E-24 T 01-11-2018 IPR001279 Metallo-beta-lactamase AFULGI_00021040 d0fafe8095e3adca5d98eff1ac178ad1 291 Gene3D G3DSA:3.60.15.10 5 260 3.7E-64 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFULGI_00012550 34f4a5c8bead32e5cb31b5ce8ca4f7b3 222 Gene3D G3DSA:3.60.21.10 19 157 7.2E-10 T 01-11-2018 IPR029052 Metallo-dependent phosphatase-like AFULGI_00012550 34f4a5c8bead32e5cb31b5ce8ca4f7b3 222 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 18 148 2.1E-8 T 01-11-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 AFULGI_00012550 34f4a5c8bead32e5cb31b5ce8ca4f7b3 222 SUPERFAMILY SSF56300 18 160 3.32E-17 T 01-11-2018 AFULGI_00012550 34f4a5c8bead32e5cb31b5ce8ca4f7b3 222 TIGRFAM TIGR00024 SbcD_rel_arch: putative phosphoesterase 1 221 7.4E-97 T 01-11-2018 IPR004376 Conserved hypothetical protein CHP00024, phosphoesterase-like AFULGI_00012550 34f4a5c8bead32e5cb31b5ce8ca4f7b3 222 PIRSF PIRSF000887 1 222 1.3E-68 T 01-11-2018 IPR024173 Phosphoesterase, MJ0037 AFULGI_00005060 ad198b84e3f82922f9e89c00adf3d915 781 Gene3D G3DSA:1.10.132.60 606 781 1.0E-47 T 01-11-2018 AFULGI_00005060 ad198b84e3f82922f9e89c00adf3d915 781 Pfam PF03104 DNA polymerase family B, exonuclease domain 197 291 1.3E-16 T 01-11-2018 IPR006133 DNA-directed DNA polymerase, family B, exonuclease domain KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFULGI_00005060 ad198b84e3f82922f9e89c00adf3d915 781 Pfam PF03104 DNA polymerase family B, exonuclease domain 29 194 3.0E-15 T 01-11-2018 IPR006133 DNA-directed DNA polymerase, family B, exonuclease domain KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFULGI_00005060 ad198b84e3f82922f9e89c00adf3d915 781 Gene3D G3DSA:3.30.420.10 136 360 2.1E-114 T 01-11-2018 IPR036397 Ribonuclease H superfamily GO:0003676 AFULGI_00005060 ad198b84e3f82922f9e89c00adf3d915 781 SMART SM00486 160 555 7.6E-128 T 01-11-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFULGI_00005060 ad198b84e3f82922f9e89c00adf3d915 781 ProSitePatterns PS00116 DNA polymerase family B signature. 543 551 - T 01-11-2018 IPR017964 DNA-directed DNA polymerase, family B, conserved site GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFULGI_00005060 ad198b84e3f82922f9e89c00adf3d915 781 Gene3D G3DSA:3.90.1600.10 391 594 8.1E-65 T 01-11-2018 IPR023211 DNA polymerase, palm domain superfamily KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFULGI_00005060 ad198b84e3f82922f9e89c00adf3d915 781 TIGRFAM TIGR00592 pol2: DNA polymerase (pol2) 390 759 2.2E-84 T 01-11-2018 AFULGI_00005060 ad198b84e3f82922f9e89c00adf3d915 781 SUPERFAMILY SSF56672 361 771 3.23E-115 T 01-11-2018 AFULGI_00005060 ad198b84e3f82922f9e89c00adf3d915 781 Gene3D G3DSA:3.30.342.10 9 377 2.1E-114 T 01-11-2018 AFULGI_00005060 ad198b84e3f82922f9e89c00adf3d915 781 Gene3D G3DSA:1.10.287.690 452 505 8.1E-65 T 01-11-2018 AFULGI_00005060 ad198b84e3f82922f9e89c00adf3d915 781 SUPERFAMILY SSF53098 5 382 2.12E-75 T 01-11-2018 IPR012337 Ribonuclease H-like superfamily AFULGI_00005060 ad198b84e3f82922f9e89c00adf3d915 781 Pfam PF00136 DNA polymerase family B 348 759 1.6E-74 T 01-11-2018 IPR006134 DNA-directed DNA polymerase, family B, multifunctional domain GO:0000166|GO:0003677 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFULGI_00005060 ad198b84e3f82922f9e89c00adf3d915 781 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 489 501 2.2E-10 T 01-11-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFULGI_00005060 ad198b84e3f82922f9e89c00adf3d915 781 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 541 549 2.2E-10 T 01-11-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFULGI_00005060 ad198b84e3f82922f9e89c00adf3d915 781 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 407 420 2.2E-10 T 01-11-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFULGI_00013560 82ea5ef3862e506db77c992ec96c1cb7 104 Gene3D G3DSA:3.30.56.30 1 104 5.1E-41 T 01-11-2018 IPR036521 Signal recognition particle, subunit SRP19-like superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 AFULGI_00013560 82ea5ef3862e506db77c992ec96c1cb7 104 SUPERFAMILY SSF69695 2 102 2.75E-29 T 01-11-2018 IPR036521 Signal recognition particle, subunit SRP19-like superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 AFULGI_00013560 82ea5ef3862e506db77c992ec96c1cb7 104 Hamap MF_00305 Signal recognition particle 19 kDa protein [srp19]. 5 87 28.784 T 01-11-2018 IPR022938 Signal recognition particle, SRP19 subunit, archaeal-type AFULGI_00013560 82ea5ef3862e506db77c992ec96c1cb7 104 Pfam PF01922 SRP19 protein 5 87 1.6E-21 T 01-11-2018 IPR002778 Signal recognition particle, SRP19 subunit GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 AFULGI_00009590 97d85d053805df5d3d4d42065aa30384 59 ProSitePatterns PS01077 Ribosomal protein L37e signature. 4 24 - T 01-11-2018 IPR018267 Ribosomal protein L37e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00009590 97d85d053805df5d3d4d42065aa30384 59 Gene3D G3DSA:2.20.25.30 1 57 8.0E-21 T 01-11-2018 IPR011331 Ribosomal protein L37ae/L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFULGI_00009590 97d85d053805df5d3d4d42065aa30384 59 ProDom PD005132 RIBOSOMAL RRNA-BINDING METAL-BINDING RNA-BINDING ZINC RIBONUCLEOPROTEIN ZINC-FINGER L37 60S L37E 9 51 2.0E-17 T 01-11-2018 IPR001569 Ribosomal protein L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00009590 97d85d053805df5d3d4d42065aa30384 59 Hamap MF_00547 50S ribosomal protein L37e [rpl37e]. 2 55 21.454 T 01-11-2018 IPR001569 Ribosomal protein L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00009590 97d85d053805df5d3d4d42065aa30384 59 Pfam PF01907 Ribosomal protein L37e 3 56 8.7E-22 T 01-11-2018 IPR001569 Ribosomal protein L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00009590 97d85d053805df5d3d4d42065aa30384 59 SUPERFAMILY SSF57829 1 56 3.84E-20 T 01-11-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 AFULGI_00013000 324dab4a51284c958cb146456fc2842a 187 ProDom PD695862 AF1173 AF0136 AF2020 6 150 0.001 T 01-11-2018 AFULGI_00021550 fd0d902967877b5102df8b071962ff06 201 Pfam PF03358 NADPH-dependent FMN reductase 1 137 1.8E-34 T 01-11-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 AFULGI_00021550 fd0d902967877b5102df8b071962ff06 201 Gene3D G3DSA:3.40.50.360 2 198 3.9E-39 T 01-11-2018 IPR029039 Flavoprotein-like superfamily AFULGI_00021550 fd0d902967877b5102df8b071962ff06 201 SUPERFAMILY SSF52218 1 194 1.8E-42 T 01-11-2018 IPR029039 Flavoprotein-like superfamily AFULGI_00010080 8486423f11d926686f9b5520cb04d5b8 73 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 2 72 2.8E-13 T 01-11-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 AFULGI_00010080 8486423f11d926686f9b5520cb04d5b8 73 Gene3D G3DSA:3.40.50.10860 1 73 8.0E-20 T 01-11-2018 AFULGI_00010080 8486423f11d926686f9b5520cb04d5b8 73 SUPERFAMILY SSF53223 1 73 2.62E-19 T 01-11-2018 AFULGI_00010080 8486423f11d926686f9b5520cb04d5b8 73 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 26 39 - T 01-11-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 AFULGI_00012790 92afbe5518ee50cfb2ee6781608c30c7 315 Gene3D G3DSA:3.10.270.10 14 296 7.9E-73 T 01-11-2018 AFULGI_00012790 92afbe5518ee50cfb2ee6781608c30c7 315 Pfam PF02649 Type I GTP cyclohydrolase folE2 2 291 3.7E-78 T 01-11-2018 IPR003801 GTP cyclohydrolase FolE2/MptA GO:0003933 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852 AFULGI_00012790 92afbe5518ee50cfb2ee6781608c30c7 315 Hamap MF_01527_A GTP cyclohydrolase FolE2 [folE2]. 1 295 38.482 T 01-11-2018 IPR022840 GTP cyclohydrolase MptA GO:0003933 KEGG: 00790+3.5.4.39|MetaCyc: PWY-6797|MetaCyc: PWY-7853 AFULGI_00012790 92afbe5518ee50cfb2ee6781608c30c7 315 TIGRFAM TIGR00294 TIGR00294: GTP cyclohydrolase 4 308 7.1E-151 T 01-11-2018 IPR003801 GTP cyclohydrolase FolE2/MptA GO:0003933 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852 AFULGI_00003810 f1a6a17d2936e064c673f0f6330c8180 251 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 1 208 5.2E-25 T 01-11-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 AFULGI_00003810 f1a6a17d2936e064c673f0f6330c8180 251 Gene3D G3DSA:3.30.950.10 112 251 8.1E-56 T 01-11-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 AFULGI_00003810 f1a6a17d2936e064c673f0f6330c8180 251 PIRSF PIRSF036432 1 246 5.6E-85 T 01-11-2018 IPR004551 Diphthine synthase GO:0004164|GO:0017183 Reactome: R-HSA-5358493 AFULGI_00003810 f1a6a17d2936e064c673f0f6330c8180 251 TIGRFAM TIGR00522 dph5: diphthine synthase 1 243 4.9E-115 T 01-11-2018 IPR004551 Diphthine synthase GO:0004164|GO:0017183 Reactome: R-HSA-5358493 AFULGI_00003810 f1a6a17d2936e064c673f0f6330c8180 251 SUPERFAMILY SSF53790 1 246 1.15E-50 T 01-11-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 AFULGI_00003810 f1a6a17d2936e064c673f0f6330c8180 251 Hamap MF_01084 Diphthine synthase [dphB]. 1 242 32.115 T 01-11-2018 IPR004551 Diphthine synthase GO:0004164|GO:0017183 Reactome: R-HSA-5358493 AFULGI_00003810 f1a6a17d2936e064c673f0f6330c8180 251 Gene3D G3DSA:3.40.1010.10 1 111 1.5E-35 T 01-11-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 AFULGI_00001810 825fc9dd870bf90e05a042eaca38556d 540 SUPERFAMILY SSF56801 8 537 9.16E-126 T 01-11-2018 AFULGI_00001810 825fc9dd870bf90e05a042eaca38556d 540 Pfam PF00501 AMP-binding enzyme 18 434 3.1E-88 T 01-11-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFULGI_00001810 825fc9dd870bf90e05a042eaca38556d 540 Pfam PF13193 AMP-binding enzyme C-terminal domain 444 524 5.8E-16 T 01-11-2018 IPR025110 AMP-binding enzyme, C-terminal domain AFULGI_00001810 825fc9dd870bf90e05a042eaca38556d 540 ProSitePatterns PS00455 Putative AMP-binding domain signature. 171 182 - T 01-11-2018 IPR020845 AMP-binding, conserved site AFULGI_00001810 825fc9dd870bf90e05a042eaca38556d 540 Gene3D G3DSA:3.40.50.12780 2 429 1.9E-101 T 01-11-2018 AFULGI_00001810 825fc9dd870bf90e05a042eaca38556d 540 Gene3D G3DSA:3.30.300.310 430 538 2.7E-32 T 01-11-2018 AFULGI_00008700 eb4de506ca568e51f6f6f65aa0a1d3da 271 SUPERFAMILY SSF103481 175 269 4.18E-10 T 01-11-2018 AFULGI_00008700 eb4de506ca568e51f6f6f65aa0a1d3da 271 SUPERFAMILY SSF103481 40 130 1.07E-11 T 01-11-2018 AFULGI_00008700 eb4de506ca568e51f6f6f65aa0a1d3da 271 Pfam PF00892 EamA-like transporter family 135 268 8.3E-23 T 01-11-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFULGI_00008700 eb4de506ca568e51f6f6f65aa0a1d3da 271 Pfam PF00892 EamA-like transporter family 7 128 7.2E-23 T 01-11-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFULGI_00014800 412128e1027c37da3cc6f0d50fff43c4 221 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 32 191 7.8E-25 T 01-11-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain AFULGI_00014800 412128e1027c37da3cc6f0d50fff43c4 221 TIGRFAM TIGR00073 hypB: hydrogenase accessory protein HypB 1 213 6.6E-99 T 01-11-2018 IPR004392 Hydrogenase maturation factor HypB GO:0016151|GO:0051604 AFULGI_00014800 412128e1027c37da3cc6f0d50fff43c4 221 Gene3D G3DSA:3.40.50.300 1 221 3.5E-60 T 01-11-2018 AFULGI_00014800 412128e1027c37da3cc6f0d50fff43c4 221 PIRSF PIRSF005624 1 221 1.3E-82 T 01-11-2018 IPR012202 [NiFe]-hydrogenase/urease maturation factor, Ni2-binding GTPase GO:0003924|GO:0016151 AFULGI_00014800 412128e1027c37da3cc6f0d50fff43c4 221 SUPERFAMILY SSF52540 8 213 3.78E-26 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00008070 21c26119c4a81273de008a553537fe44 201 Gene3D G3DSA:3.40.1010.10 1 112 1.9E-19 T 01-11-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 AFULGI_00008070 21c26119c4a81273de008a553537fe44 201 PIRSF PIRSF036427 1 201 2.2E-42 T 01-11-2018 IPR012382 Precorrin-2 C(20)-methyltransferase GO:0008757|GO:0009236|GO:0030788 AFULGI_00008070 21c26119c4a81273de008a553537fe44 201 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 5 180 1.7E-24 T 01-11-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 AFULGI_00008070 21c26119c4a81273de008a553537fe44 201 SUPERFAMILY SSF53790 3 199 6.15E-28 T 01-11-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 AFULGI_00010250 2987caab76fd6fc78d948c767e4d3180 326 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 8 139 2.3E-12 T 01-11-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 AFULGI_00010250 2987caab76fd6fc78d948c767e4d3180 326 PIRSF PIRSF036497 1 325 2.5E-98 T 01-11-2018 IPR022697 Homoserine dehydrogenase lacking ACT domain GO:0004412 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 AFULGI_00010250 2987caab76fd6fc78d948c767e4d3180 326 Gene3D G3DSA:3.40.50.720 4 319 1.9E-118 T 01-11-2018 AFULGI_00010250 2987caab76fd6fc78d948c767e4d3180 326 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 193 215 - T 01-11-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 AFULGI_00010250 2987caab76fd6fc78d948c767e4d3180 326 SUPERFAMILY SSF55347 147 306 9.15E-47 T 01-11-2018 AFULGI_00010250 2987caab76fd6fc78d948c767e4d3180 326 Gene3D G3DSA:3.30.360.10 158 302 1.9E-118 T 01-11-2018 AFULGI_00010250 2987caab76fd6fc78d948c767e4d3180 326 Pfam PF00742 Homoserine dehydrogenase 147 318 4.5E-58 T 01-11-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 AFULGI_00010250 2987caab76fd6fc78d948c767e4d3180 326 SUPERFAMILY SSF51735 1 168 1.82E-27 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily AFULGI_00003200 289cb55c51f0469a18b6edc957c86370 285 Gene3D G3DSA:3.40.50.720 3 269 1.5E-94 T 01-11-2018 AFULGI_00003200 289cb55c51f0469a18b6edc957c86370 285 Pfam PF04321 RmlD substrate binding domain 1 281 1.9E-86 T 01-11-2018 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581|Reactome: R-HSA-5689880 AFULGI_00003200 289cb55c51f0469a18b6edc957c86370 285 SUPERFAMILY SSF51735 1 281 3.22E-83 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily AFULGI_00003200 289cb55c51f0469a18b6edc957c86370 285 TIGRFAM TIGR01214 rmlD: dTDP-4-dehydrorhamnose reductase 2 281 1.9E-107 T 01-11-2018 IPR005913 dTDP-4-dehydrorhamnose reductase family Reactome: R-HSA-156581|Reactome: R-HSA-5689880 AFULGI_00003200 289cb55c51f0469a18b6edc957c86370 285 Gene3D G3DSA:3.90.25.10 162 275 1.5E-94 T 01-11-2018 AFULGI_00007200 da4cb61c798edea92a07a84a8678f77b 248 Gene3D G3DSA:1.10.3720.10 43 244 1.7E-21 T 01-11-2018 IPR035906 MetI-like superfamily AFULGI_00007200 da4cb61c798edea92a07a84a8678f77b 248 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 69 242 8.1E-13 T 01-11-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFULGI_00007200 da4cb61c798edea92a07a84a8678f77b 248 SUPERFAMILY SSF161098 46 236 1.01E-22 T 01-11-2018 IPR035906 MetI-like superfamily AFULGI_00002060 dd44e007e4683c95569b1670574efd1e 506 SMART SM00878 334 439 8.7E-64 T 01-11-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 AFULGI_00002060 dd44e007e4683c95569b1670574efd1e 506 SUPERFAMILY SSF52440 1 111 1.29E-49 T 01-11-2018 IPR016185 Pre-ATP-grasp domain superfamily AFULGI_00002060 dd44e007e4683c95569b1670574efd1e 506 SUPERFAMILY SSF56059 83 350 1.24E-72 T 01-11-2018 AFULGI_00002060 dd44e007e4683c95569b1670574efd1e 506 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 152 166 - T 01-11-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AFULGI_00002060 dd44e007e4683c95569b1670574efd1e 506 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 1.7E-46 T 01-11-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 AFULGI_00002060 dd44e007e4683c95569b1670574efd1e 506 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 116 321 3.5E-75 T 01-11-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AFULGI_00002060 dd44e007e4683c95569b1670574efd1e 506 TIGRFAM TIGR00514 accC: acetyl-CoA carboxylase, biotin carboxylase subunit 1 442 3.6E-197 T 01-11-2018 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase GO:0016874 AFULGI_00002060 dd44e007e4683c95569b1670574efd1e 506 Pfam PF02785 Biotin carboxylase C-terminal domain 334 440 4.1E-40 T 01-11-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 AFULGI_00002060 dd44e007e4683c95569b1670574efd1e 506 SUPERFAMILY SSF51246 329 441 1.2E-43 T 01-11-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 AFULGI_00002060 dd44e007e4683c95569b1670574efd1e 506 Gene3D G3DSA:3.30.470.130 1 446 4.1E-192 T 01-11-2018 AFULGI_00014640 ec1d2f0214292fea64b1de1603d0a421 319 SUPERFAMILY SSF50998 3 318 7.69E-12 T 01-11-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily AFULGI_00014640 ec1d2f0214292fea64b1de1603d0a421 319 Gene3D G3DSA:2.130.10.10 3 318 4.4E-6 T 01-11-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 AFULGI_00013210 3a9d60f3f72f466b8e4a2acc1e584e31 506 ProSitePatterns PS00456 Sodium:solute symporter family signature 1. 152 177 - T 01-11-2018 IPR018212 Sodium/solute symporter, conserved site AFULGI_00013210 3a9d60f3f72f466b8e4a2acc1e584e31 506 Pfam PF00474 Sodium:solute symporter family 31 461 2.2E-48 T 01-11-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 AFULGI_00013210 3a9d60f3f72f466b8e4a2acc1e584e31 506 Gene3D G3DSA:1.20.1730.10 5 505 5.9E-61 T 01-11-2018 IPR038377 Sodium/glucose symporter superfamily AFULGI_00021590 d4345c37017c887dd4541f66416c78d0 180 Gene3D G3DSA:3.40.50.300 1 177 4.8E-45 T 01-11-2018 AFULGI_00021590 d4345c37017c887dd4541f66416c78d0 180 Hamap MF_00239 Cytidylate kinase [cmk]. 1 174 48.011 T 01-11-2018 IPR011892 Cytidylate kinase, putative GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 AFULGI_00021590 d4345c37017c887dd4541f66416c78d0 180 Pfam PF13238 AAA domain 3 114 3.0E-17 T 01-11-2018 AFULGI_00021590 d4345c37017c887dd4541f66416c78d0 180 TIGRFAM TIGR02173 cyt_kin_arch: putative cytidylate kinase 1 171 3.1E-71 T 01-11-2018 IPR011892 Cytidylate kinase, putative GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 AFULGI_00021590 d4345c37017c887dd4541f66416c78d0 180 SUPERFAMILY SSF52540 1 170 2.79E-27 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00016230 21a8b54f1ad0bc4ff623c56c1ea505de 137 SUPERFAMILY SSF88723 1 132 9.53E-20 T 01-11-2018 IPR029060 PIN-like domain superfamily AFULGI_00016230 21a8b54f1ad0bc4ff623c56c1ea505de 137 Pfam PF01850 PIN domain 3 132 9.8E-22 T 01-11-2018 IPR002716 PIN domain AFULGI_00016230 21a8b54f1ad0bc4ff623c56c1ea505de 137 Gene3D G3DSA:3.40.50.1010 2 136 8.0E-20 T 01-11-2018 AFULGI_00016230 21a8b54f1ad0bc4ff623c56c1ea505de 137 SMART SM00670 1 131 5.1E-5 T 01-11-2018 IPR002716 PIN domain AFULGI_00018600 1ec2bfc1f581d3f2bcdece542b2b4b6c 471 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 98 268 8.5E-27 T 01-11-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFULGI_00018600 1ec2bfc1f581d3f2bcdece542b2b4b6c 471 Gene3D G3DSA:3.40.50.800 280 396 1.3E-28 T 01-11-2018 IPR036621 Anticodon-binding domain superfamily AFULGI_00018600 1ec2bfc1f581d3f2bcdece542b2b4b6c 471 SMART SM00946 395 471 6.7E-10 T 01-11-2018 IPR016061 Proline-tRNA ligase, class II, C-terminal GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 AFULGI_00018600 1ec2bfc1f581d3f2bcdece542b2b4b6c 471 Gene3D G3DSA:3.30.930.10 8 278 1.3E-87 T 01-11-2018 AFULGI_00018600 1ec2bfc1f581d3f2bcdece542b2b4b6c 471 PRINTS PR01046 Prolyl-tRNA synthetase signature 131 139 3.7E-12 T 01-11-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 AFULGI_00018600 1ec2bfc1f581d3f2bcdece542b2b4b6c 471 PRINTS PR01046 Prolyl-tRNA synthetase signature 101 112 3.7E-12 T 01-11-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 AFULGI_00018600 1ec2bfc1f581d3f2bcdece542b2b4b6c 471 PRINTS PR01046 Prolyl-tRNA synthetase signature 60 78 3.7E-12 T 01-11-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 AFULGI_00018600 1ec2bfc1f581d3f2bcdece542b2b4b6c 471 PRINTS PR01046 Prolyl-tRNA synthetase signature 141 152 3.7E-12 T 01-11-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 AFULGI_00018600 1ec2bfc1f581d3f2bcdece542b2b4b6c 471 Gene3D G3DSA:3.30.110.30 397 470 4.0E-5 T 01-11-2018 IPR017449 Prolyl-tRNA synthetase, class II GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 AFULGI_00018600 1ec2bfc1f581d3f2bcdece542b2b4b6c 471 SUPERFAMILY SSF55681 7 272 4.38E-80 T 01-11-2018 AFULGI_00018600 1ec2bfc1f581d3f2bcdece542b2b4b6c 471 SUPERFAMILY SSF52954 274 392 1.36E-27 T 01-11-2018 AFULGI_00018600 1ec2bfc1f581d3f2bcdece542b2b4b6c 471 Hamap MF_01571 Proline--tRNA ligase [proS]. 2 471 38.658 T 01-11-2018 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 AFULGI_00018600 1ec2bfc1f581d3f2bcdece542b2b4b6c 471 TIGRFAM TIGR00408 proS_fam_I: proline--tRNA ligase 4 471 4.0E-209 T 01-11-2018 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 AFULGI_00018600 1ec2bfc1f581d3f2bcdece542b2b4b6c 471 Pfam PF03129 Anticodon binding domain 285 371 1.7E-17 T 01-11-2018 IPR004154 Anticodon-binding AFULGI_00018600 1ec2bfc1f581d3f2bcdece542b2b4b6c 471 SUPERFAMILY SSF64586 402 471 9.02E-10 T 01-11-2018 IPR017449 Prolyl-tRNA synthetase, class II GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 AFULGI_00024560 8183036d2a631bd4ff261f4250d2b482 287 Pfam PF00549 CoA-ligase 151 270 1.7E-17 T 01-11-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AFULGI_00024560 8183036d2a631bd4ff261f4250d2b482 287 SUPERFAMILY SSF52210 123 285 1.13E-49 T 01-11-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AFULGI_00024560 8183036d2a631bd4ff261f4250d2b482 287 Gene3D G3DSA:3.40.50.720 1 123 1.1E-51 T 01-11-2018 AFULGI_00024560 8183036d2a631bd4ff261f4250d2b482 287 SUPERFAMILY SSF51735 1 122 1.28E-44 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily AFULGI_00024560 8183036d2a631bd4ff261f4250d2b482 287 PIRSF PIRSF001553 1 287 3.8E-132 T 01-11-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 AFULGI_00024560 8183036d2a631bd4ff261f4250d2b482 287 Hamap MF_01988 Succinate--CoA ligase [ADP-forming] subunit alpha [sucD]. 1 287 43.565 T 01-11-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 AFULGI_00024560 8183036d2a631bd4ff261f4250d2b482 287 Gene3D G3DSA:3.40.50.261 124 287 6.8E-69 T 01-11-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AFULGI_00024560 8183036d2a631bd4ff261f4250d2b482 287 SMART SM00881 4 100 2.7E-38 T 01-11-2018 IPR003781 CoA-binding GO:0048037 AFULGI_00024560 8183036d2a631bd4ff261f4250d2b482 287 PRINTS PR01798 Succinyl-CoA synthase signature 177 195 3.3E-35 T 01-11-2018 AFULGI_00024560 8183036d2a631bd4ff261f4250d2b482 287 PRINTS PR01798 Succinyl-CoA synthase signature 239 256 3.3E-35 T 01-11-2018 AFULGI_00024560 8183036d2a631bd4ff261f4250d2b482 287 PRINTS PR01798 Succinyl-CoA synthase signature 208 221 3.3E-35 T 01-11-2018 AFULGI_00024560 8183036d2a631bd4ff261f4250d2b482 287 PRINTS PR01798 Succinyl-CoA synthase signature 82 99 3.3E-35 T 01-11-2018 AFULGI_00024560 8183036d2a631bd4ff261f4250d2b482 287 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 3 287 7.1E-146 T 01-11-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 AFULGI_00024560 8183036d2a631bd4ff261f4250d2b482 287 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 235 248 - T 01-11-2018 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site AFULGI_00024560 8183036d2a631bd4ff261f4250d2b482 287 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 152 181 - T 01-11-2018 IPR033847 ATP-citrate lyase/succinyl-CoA ligase, conserved site AFULGI_00024560 8183036d2a631bd4ff261f4250d2b482 287 Pfam PF02629 CoA binding domain 6 99 5.7E-34 T 01-11-2018 IPR003781 CoA-binding GO:0048037 AFULGI_00007080 0aa61edd786d51d83a4ebcca07711aeb 326 SUPERFAMILY SSF53659 2 325 1.13E-126 T 01-11-2018 AFULGI_00007080 0aa61edd786d51d83a4ebcca07711aeb 326 Gene3D G3DSA:3.40.718.10 1 326 1.7E-141 T 01-11-2018 AFULGI_00007080 0aa61edd786d51d83a4ebcca07711aeb 326 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 218 237 - T 01-11-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 AFULGI_00007080 0aa61edd786d51d83a4ebcca07711aeb 326 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 3 321 3.1E-107 T 01-11-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 AFULGI_00007080 0aa61edd786d51d83a4ebcca07711aeb 326 SMART SM01329 3 321 5.0E-190 T 01-11-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 AFULGI_00007080 0aa61edd786d51d83a4ebcca07711aeb 326 TIGRFAM TIGR02088 LEU3_arch: isopropylmalate/isohomocitrate dehydrogenases 4 322 1.9E-156 T 01-11-2018 IPR011828 Isopropylmalate/isohomocitrate dehydrogenase GO:0003862|GO:0009098|GO:0051287|GO:0055114 AFULGI_00002160 df0d73d6b43bd2df8e5a3282380d1712 257 Pfam PF01791 DeoC/LacD family aldolase 17 223 1.0E-44 T 01-11-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 AFULGI_00002160 df0d73d6b43bd2df8e5a3282380d1712 257 Gene3D G3DSA:3.20.20.70 1 253 4.4E-82 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFULGI_00002160 df0d73d6b43bd2df8e5a3282380d1712 257 TIGRFAM TIGR01949 AroFGH_arch: predicted phospho-2-dehydro-3-deoxyheptonate aldolase 2 249 1.6E-122 T 01-11-2018 IPR010210 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase GO:0009073|GO:0016836 KEGG: 00400+2.2.1.10|MetaCyc: PWY-6160 AFULGI_00002160 df0d73d6b43bd2df8e5a3282380d1712 257 SMART SM01133 17 224 8.6E-47 T 01-11-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 AFULGI_00002160 df0d73d6b43bd2df8e5a3282380d1712 257 SUPERFAMILY SSF51569 3 240 7.32E-67 T 01-11-2018 AFULGI_00002160 df0d73d6b43bd2df8e5a3282380d1712 257 PIRSF PIRSF038992 1 253 2.3E-75 T 01-11-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 AFULGI_00002160 df0d73d6b43bd2df8e5a3282380d1712 257 Hamap MF_00960 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [aroA']. 1 252 55.98 T 01-11-2018 IPR010210 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase GO:0009073|GO:0016836 KEGG: 00400+2.2.1.10|MetaCyc: PWY-6160 AFULGI_00003440 5b22b89e7b47d23caa0c39b1bec94d30 164 Gene3D G3DSA:3.40.630.30 1 94 6.0E-12 T 01-11-2018 AFULGI_00003440 5b22b89e7b47d23caa0c39b1bec94d30 164 SUPERFAMILY SSF55729 9 86 5.89E-10 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase AFULGI_00003440 5b22b89e7b47d23caa0c39b1bec94d30 164 Pfam PF14542 GCN5-related N-acetyl-transferase 11 80 5.3E-12 T 01-11-2018 IPR031165 Yjdj-type Gcn5-related N-acetyltransferase AFULGI_00013860 08dabd3f13f3b4a0c7e37d0b190e7fa1 407 Gene3D G3DSA:3.40.50.10690 171 407 1.6E-104 T 01-11-2018 AFULGI_00013860 08dabd3f13f3b4a0c7e37d0b190e7fa1 407 TIGRFAM TIGR00300 TIGR00300: TIGR00300 family protein 1 403 8.0E-223 T 01-11-2018 IPR005239 Conserved hypothetical protein CHP00300 AFULGI_00013860 08dabd3f13f3b4a0c7e37d0b190e7fa1 407 Gene3D G3DSA:3.30.70.2690 2 97 3.9E-32 T 01-11-2018 AFULGI_00013860 08dabd3f13f3b4a0c7e37d0b190e7fa1 407 Pfam PF04455 LOR/SDH bifunctional enzyme conserved region 4 102 3.0E-37 T 01-11-2018 IPR007545 LOR/SDH bifunctional enzyme, conserved domain AFULGI_00003900 4de0c3390b0e41b16dd76312586a71ef 246 SUPERFAMILY SSF53850 1 245 2.02E-60 T 01-11-2018 AFULGI_00003900 4de0c3390b0e41b16dd76312586a71ef 246 Hamap MF_00995 Chorismate dehydratase [mqnA]. 2 245 27.486 T 01-11-2018 IPR030868 Chorismate dehydratase GO:0009234|GO:0016829 KEGG: 00130+4.2.1.151|MetaCyc: PWY-7371|MetaCyc: PWY-7374 AFULGI_00003900 4de0c3390b0e41b16dd76312586a71ef 246 Gene3D G3DSA:3.40.190.10 69 163 1.0E-52 T 01-11-2018 AFULGI_00003900 4de0c3390b0e41b16dd76312586a71ef 246 Gene3D G3DSA:3.40.190.10 2 235 1.0E-52 T 01-11-2018 AFULGI_00003900 4de0c3390b0e41b16dd76312586a71ef 246 Pfam PF02621 Menaquinone biosynthesis 1 240 5.3E-56 T 01-11-2018 IPR003773 Menaquinone biosynthesis enzyme AFULGI_00023590 bf7964cdf0af97599562982bb37ab84c 2556 Gene3D G3DSA:2.160.20.10 2081 2386 3.1E-15 T 01-11-2018 IPR012334 Pectin lyase fold AFULGI_00023590 bf7964cdf0af97599562982bb37ab84c 2556 SMART SM00710 2099 2120 3000.0 T 01-11-2018 IPR006626 Parallel beta-helix repeat AFULGI_00023590 bf7964cdf0af97599562982bb37ab84c 2556 SMART SM00710 2156 2178 1500.0 T 01-11-2018 IPR006626 Parallel beta-helix repeat AFULGI_00023590 bf7964cdf0af97599562982bb37ab84c 2556 SMART SM00710 2289 2311 150.0 T 01-11-2018 IPR006626 Parallel beta-helix repeat AFULGI_00023590 bf7964cdf0af97599562982bb37ab84c 2556 SMART SM00710 2260 2282 350.0 T 01-11-2018 IPR006626 Parallel beta-helix repeat AFULGI_00023590 bf7964cdf0af97599562982bb37ab84c 2556 SMART SM00710 2233 2259 83.0 T 01-11-2018 IPR006626 Parallel beta-helix repeat AFULGI_00023590 bf7964cdf0af97599562982bb37ab84c 2556 SMART SM00710 2210 2232 100.0 T 01-11-2018 IPR006626 Parallel beta-helix repeat AFULGI_00023590 bf7964cdf0af97599562982bb37ab84c 2556 Pfam PF13229 Right handed beta helix region 2151 2321 3.3E-9 T 01-11-2018 IPR039448 Right handed beta helix domain AFULGI_00023590 bf7964cdf0af97599562982bb37ab84c 2556 SUPERFAMILY SSF51126 2086 2327 9.67E-13 T 01-11-2018 IPR011050 Pectin lyase fold/virulence factor AFULGI_00022250 d9ef565c6008d354ffe2b76628d9f705 136 Pfam PF01870 Archaeal holliday junction resolvase (hjc) 7 98 5.7E-33 T 01-11-2018 IPR002732 Holliday junction resolvase Hjc AFULGI_00022250 d9ef565c6008d354ffe2b76628d9f705 136 ProDom PD015874 RESOLVASE HOLLIDAY JUNCTION ARCHAEAL HOLLIDAY-JUNCTION TYPE MJ0497 ORF-C21_024 PF1503 NEQ424 9 97 5.0E-46 T 01-11-2018 IPR014428 Holliday junction resolvase Hjc, archaeal AFULGI_00022250 d9ef565c6008d354ffe2b76628d9f705 136 PIRSF PIRSF004985 1 135 1.2E-45 T 01-11-2018 IPR014428 Holliday junction resolvase Hjc, archaeal AFULGI_00022250 d9ef565c6008d354ffe2b76628d9f705 136 SUPERFAMILY SSF52980 5 131 1.61E-27 T 01-11-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 AFULGI_00022250 d9ef565c6008d354ffe2b76628d9f705 136 Gene3D G3DSA:3.40.1350.10 1 136 8.1E-56 T 01-11-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 AFULGI_00022250 d9ef565c6008d354ffe2b76628d9f705 136 Hamap MF_01490 Holliday junction resolvase Hjc [hjc]. 1 132 39.26 T 01-11-2018 IPR014428 Holliday junction resolvase Hjc, archaeal AFULGI_00005180 85e5d0ea39d1922bf4d0712938e8dd67 336 Gene3D G3DSA:3.20.20.70 8 319 1.6E-147 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFULGI_00005180 85e5d0ea39d1922bf4d0712938e8dd67 336 Pfam PF05690 Thiazole biosynthesis protein ThiG 241 298 9.3E-7 T 01-11-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 AFULGI_00005180 85e5d0ea39d1922bf4d0712938e8dd67 336 SUPERFAMILY SSF51366 24 310 4.0E-63 T 01-11-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 AFULGI_00005180 85e5d0ea39d1922bf4d0712938e8dd67 336 Hamap MF_01824 Pyridoxal 5'-phosphate synthase subunit PdxS [pdxS]. 10 336 53.132 T 01-11-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 AFULGI_00005180 85e5d0ea39d1922bf4d0712938e8dd67 336 Pfam PF01680 SOR/SNZ family 14 215 5.9E-95 T 01-11-2018 IPR033755 PdxS/SNZ N-terminal domain KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 AFULGI_00005180 85e5d0ea39d1922bf4d0712938e8dd67 336 ProSitePatterns PS01235 PdxS/SNZ family signature. 247 265 - T 01-11-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 AFULGI_00005180 85e5d0ea39d1922bf4d0712938e8dd67 336 PIRSF PIRSF029271 1 336 7.3E-154 T 01-11-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 AFULGI_00005180 85e5d0ea39d1922bf4d0712938e8dd67 336 TIGRFAM TIGR00343 TIGR00343: pyridoxal 5'-phosphate synthase, synthase subunit Pdx1 15 335 9.8E-159 T 01-11-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 AFULGI_00015300 77c897d84bd6fff31ad080f16f274074 153 Gene3D G3DSA:3.40.50.960 1 153 1.6E-54 T 01-11-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AFULGI_00015300 77c897d84bd6fff31ad080f16f274074 153 SUPERFAMILY SSF52121 1 134 3.4E-27 T 01-11-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AFULGI_00015300 77c897d84bd6fff31ad080f16f274074 153 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 2 127 2.8E-12 T 01-11-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AFULGI_00015300 77c897d84bd6fff31ad080f16f274074 153 PIRSF PIRSF015750 1 153 1.7E-76 T 01-11-2018 IPR006399 Riboflavin synthase, archaeal GO:0004746|GO:0009231 KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AFULGI_00015300 77c897d84bd6fff31ad080f16f274074 153 TIGRFAM TIGR01506 ribC_arch: riboflavin synthase 2 151 5.0E-85 T 01-11-2018 IPR006399 Riboflavin synthase, archaeal GO:0004746|GO:0009231 KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AFULGI_00023300 f74d1eb276c24c5c4c39461154059a3b 340 Gene3D G3DSA:3.40.50.300 134 340 4.4E-77 T 01-11-2018 AFULGI_00023300 f74d1eb276c24c5c4c39461154059a3b 340 SUPERFAMILY SSF52540 141 339 6.0E-50 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00023300 f74d1eb276c24c5c4c39461154059a3b 340 SMART SM00382 144 339 9.5E-11 T 01-11-2018 IPR003593 AAA+ ATPase domain AFULGI_00023300 f74d1eb276c24c5c4c39461154059a3b 340 SMART SM00962 145 340 2.4E-106 T 01-11-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 AFULGI_00023300 f74d1eb276c24c5c4c39461154059a3b 340 SUPERFAMILY SSF47364 56 132 1.05E-11 T 01-11-2018 IPR036225 SRP/SRP receptor, N-terminal Reactome: R-HSA-1799339 AFULGI_00023300 f74d1eb276c24c5c4c39461154059a3b 340 Pfam PF00448 SRP54-type protein, GTPase domain 145 339 9.5E-76 T 01-11-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 AFULGI_00023300 f74d1eb276c24c5c4c39461154059a3b 340 SMART SM00963 42 121 3.2E-8 T 01-11-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 AFULGI_00023300 f74d1eb276c24c5c4c39461154059a3b 340 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 64 340 60.217 T 01-11-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 AFULGI_00023300 f74d1eb276c24c5c4c39461154059a3b 340 Pfam PF02881 SRP54-type protein, helical bundle domain 51 117 2.8E-10 T 01-11-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 AFULGI_00023300 f74d1eb276c24c5c4c39461154059a3b 340 Gene3D G3DSA:1.20.120.140 4 128 1.4E-14 T 01-11-2018 AFULGI_00023300 f74d1eb276c24c5c4c39461154059a3b 340 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 65 339 1.3E-109 T 01-11-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 AFULGI_00004880 53683785a0cbca663c0da0f78385dfaf 179 Gene3D G3DSA:3.40.225.10 1 178 2.6E-42 T 01-11-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily AFULGI_00004880 53683785a0cbca663c0da0f78385dfaf 179 SMART SM01007 3 171 1.0E-33 T 01-11-2018 IPR001303 Class II aldolase/adducin N-terminal AFULGI_00004880 53683785a0cbca663c0da0f78385dfaf 179 SUPERFAMILY SSF53639 3 178 2.94E-38 T 01-11-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily AFULGI_00004880 53683785a0cbca663c0da0f78385dfaf 179 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 4 170 1.8E-31 T 01-11-2018 IPR001303 Class II aldolase/adducin N-terminal AFULGI_00000560 a5c1b717afa925aeef36f59ebbb35f11 61 SUPERFAMILY SSF88723 2 57 2.75E-6 T 01-11-2018 IPR029060 PIN-like domain superfamily AFULGI_00007070 c88aa1437affc12c8157ea5d9cbe3738 340 SUPERFAMILY SSF54862 237 330 2.42E-17 T 01-11-2018 AFULGI_00007070 c88aa1437affc12c8157ea5d9cbe3738 340 Gene3D G3DSA:3.30.70.20 265 302 1.1E-7 T 01-11-2018 AFULGI_00007070 c88aa1437affc12c8157ea5d9cbe3738 340 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 312 323 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFULGI_00007070 c88aa1437affc12c8157ea5d9cbe3738 340 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 284 295 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFULGI_00007070 c88aa1437affc12c8157ea5d9cbe3738 340 Pfam PF00037 4Fe-4S binding domain 306 328 5.7E-5 T 01-11-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFULGI_00007070 c88aa1437affc12c8157ea5d9cbe3738 340 Pfam PF00037 4Fe-4S binding domain 278 300 2.1E-8 T 01-11-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFULGI_00007070 c88aa1437affc12c8157ea5d9cbe3738 340 Gene3D G3DSA:3.30.70.20 303 337 2.2E-5 T 01-11-2018 AFULGI_00009840 b952c7be1feef522df8972b5a31cd231 549 Pfam PF05746 DALR anticodon binding domain 433 549 3.6E-33 T 01-11-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 AFULGI_00009840 b952c7be1feef522df8972b5a31cd231 549 Hamap MF_00123 Arginine--tRNA ligase [argS]. 3 549 28.572 T 01-11-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 AFULGI_00009840 b952c7be1feef522df8972b5a31cd231 549 Gene3D G3DSA:1.10.730.10 433 549 2.6E-32 T 01-11-2018 AFULGI_00009840 b952c7be1feef522df8972b5a31cd231 549 SUPERFAMILY SSF52374 104 426 1.69E-81 T 01-11-2018 AFULGI_00009840 b952c7be1feef522df8972b5a31cd231 549 SUPERFAMILY SSF55190 8 98 5.75E-17 T 01-11-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 AFULGI_00009840 b952c7be1feef522df8972b5a31cd231 549 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 23 77 2.3E-13 T 01-11-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 AFULGI_00009840 b952c7be1feef522df8972b5a31cd231 549 SUPERFAMILY SSF47323 429 549 2.03E-32 T 01-11-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFULGI_00009840 b952c7be1feef522df8972b5a31cd231 549 Gene3D G3DSA:3.40.50.620 104 432 4.7E-100 T 01-11-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFULGI_00009840 b952c7be1feef522df8972b5a31cd231 549 Gene3D G3DSA:3.30.1360.70 3 102 5.6E-22 T 01-11-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 AFULGI_00009840 b952c7be1feef522df8972b5a31cd231 549 Pfam PF00750 tRNA synthetases class I (R) 87 419 4.2E-36 T 01-11-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 AFULGI_00009840 b952c7be1feef522df8972b5a31cd231 549 SMART SM00836 433 549 4.9E-38 T 01-11-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 AFULGI_00009840 b952c7be1feef522df8972b5a31cd231 549 SMART SM01016 3 78 1.1E-17 T 01-11-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 AFULGI_00009840 b952c7be1feef522df8972b5a31cd231 549 PRINTS PR01038 Arginyl-tRNA synthetase signature 120 136 1.8E-23 T 01-11-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 AFULGI_00009840 b952c7be1feef522df8972b5a31cd231 549 PRINTS PR01038 Arginyl-tRNA synthetase signature 285 306 1.8E-23 T 01-11-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 AFULGI_00009840 b952c7be1feef522df8972b5a31cd231 549 PRINTS PR01038 Arginyl-tRNA synthetase signature 105 120 1.8E-23 T 01-11-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 AFULGI_00009840 b952c7be1feef522df8972b5a31cd231 549 PRINTS PR01038 Arginyl-tRNA synthetase signature 144 157 1.8E-23 T 01-11-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 AFULGI_00009840 b952c7be1feef522df8972b5a31cd231 549 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 24 549 7.2E-206 T 01-11-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 AFULGI_00023270 a789c57cfcdf6503b668fe9def705dda 195 SUPERFAMILY SSF111278 1 184 2.35E-53 T 01-11-2018 IPR036602 tRNA wybutosine-synthesizing-like superfamily MetaCyc: PWY-7286|Reactome: R-HSA-6782861 AFULGI_00023270 a789c57cfcdf6503b668fe9def705dda 195 Pfam PF02676 Methyltransferase TYW3 14 184 6.9E-39 T 01-11-2018 IPR003827 tRNA wybutosine-synthesizing protein MetaCyc: PWY-7286|Reactome: R-HSA-6782861 AFULGI_00023270 a789c57cfcdf6503b668fe9def705dda 195 Hamap MF_00266 tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase [taw3]. 3 186 28.921 T 01-11-2018 IPR022908 tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase GO:0008175|GO:0030488|GO:0031591 MetaCyc: PWY-7286 AFULGI_00023270 a789c57cfcdf6503b668fe9def705dda 195 Gene3D G3DSA:3.30.1960.10 1 195 2.2E-75 T 01-11-2018 IPR036602 tRNA wybutosine-synthesizing-like superfamily MetaCyc: PWY-7286|Reactome: R-HSA-6782861 AFULGI_00024240 678d141b3f8cea297fa8808b0f7aeae3 153 PIRSF PIRSF006595 6 153 1.9E-54 T 01-11-2018 IPR005369 Uncharacterised protein family UPF0179 AFULGI_00024240 678d141b3f8cea297fa8808b0f7aeae3 153 Pfam PF03684 Uncharacterised protein family (UPF0179) 9 146 3.5E-50 T 01-11-2018 IPR005369 Uncharacterised protein family UPF0179 AFULGI_00024240 678d141b3f8cea297fa8808b0f7aeae3 153 ProDom PD016182 UPF0179 TK0790 TV1250 PAE0681 PF1381 AF2154 MA3685 VNG1401C MJ1627 PH1477 8 132 1.0E-66 T 01-11-2018 IPR005369 Uncharacterised protein family UPF0179 AFULGI_00024240 678d141b3f8cea297fa8808b0f7aeae3 153 Hamap MF_00498 UPF0179 protein . 7 150 26.577 T 01-11-2018 IPR005369 Uncharacterised protein family UPF0179 AFULGI_00014450 80b905da4d39a38cea99b51b0f9e88e0 58 SUPERFAMILY SSF57829 2 55 1.81E-19 T 01-11-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 AFULGI_00014450 80b905da4d39a38cea99b51b0f9e88e0 58 Pfam PF01667 Ribosomal protein S27 2 55 7.3E-30 T 01-11-2018 IPR000592 Ribosomal protein S27e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00014450 80b905da4d39a38cea99b51b0f9e88e0 58 Gene3D G3DSA:2.20.25.100 1 58 7.2E-32 T 01-11-2018 IPR023407 Ribosomal protein S27e, zinc-binding domain superfamily AFULGI_00014450 80b905da4d39a38cea99b51b0f9e88e0 58 Hamap MF_00371 30S ribosomal protein S27e [rps27e]. 1 54 18.784 T 01-11-2018 IPR000592 Ribosomal protein S27e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00014450 80b905da4d39a38cea99b51b0f9e88e0 58 ProSitePatterns PS01168 Ribosomal protein S27e signature. 9 41 - T 01-11-2018 IPR000592 Ribosomal protein S27e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00023530 28b798e23dbb7ef40d2ee8ff172a7d59 354 TIGRFAM TIGR01109 Na_pump_decarbB: sodium ion-translocating decarboxylase, beta subunit 3 348 4.6E-175 T 01-11-2018 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3 AFULGI_00023530 28b798e23dbb7ef40d2ee8ff172a7d59 354 PIRSF PIRSF015658 1 354 1.5E-168 T 01-11-2018 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3 AFULGI_00023530 28b798e23dbb7ef40d2ee8ff172a7d59 354 Pfam PF03977 Na+-transporting oxaloacetate decarboxylase beta subunit 4 352 4.5E-156 T 01-11-2018 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3 AFULGI_00008210 7922c562075ba4e00378698d86e5c119 128 Hamap MF_00341 UPF0146 protein . 1 123 28.312 T 01-11-2018 IPR005353 Uncharacterised protein family UPF0146 AFULGI_00008210 7922c562075ba4e00378698d86e5c119 128 Pfam PF03686 Uncharacterised protein family (UPF0146) 1 123 3.6E-57 T 01-11-2018 IPR005353 Uncharacterised protein family UPF0146 AFULGI_00008210 7922c562075ba4e00378698d86e5c119 128 SUPERFAMILY SSF53335 12 92 5.26E-5 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFULGI_00008210 7922c562075ba4e00378698d86e5c119 128 PIRSF PIRSF016725 1 128 2.8E-57 T 01-11-2018 IPR005353 Uncharacterised protein family UPF0146 AFULGI_00008210 7922c562075ba4e00378698d86e5c119 128 Gene3D G3DSA:3.40.50.150 1 128 3.3E-34 T 01-11-2018 AFULGI_00008210 7922c562075ba4e00378698d86e5c119 128 ProDom PD021130 UPF0146 MJ0688 SIMILAR ARCHAEA UNCHARACTERIZED AF0739.1 MTH1000 PYRAB01940 PH0209 VNG2609C 16 105 6.0E-46 T 01-11-2018 IPR005353 Uncharacterised protein family UPF0146 AFULGI_00008230 4bc920e6d27596063f6f6a724f67af70 335 TIGRFAM TIGR00335 primase_sml: putative DNA primase, eukaryotic-type, small subunit 1 290 1.6E-112 T 01-11-2018 IPR014052 DNA primase, small subunit, eukaryotic/archaeal GO:0003896|GO:0006269 Reactome: R-HSA-113501|Reactome: R-HSA-174411|Reactome: R-HSA-174430|Reactome: R-HSA-68952|Reactome: R-HSA-68962|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183 AFULGI_00008230 4bc920e6d27596063f6f6a724f67af70 335 Hamap MF_00700 DNA primase small subunit PriS [priS]. 5 329 30.408 T 01-11-2018 IPR023639 DNA primase small subunit PriS GO:0003896 AFULGI_00008230 4bc920e6d27596063f6f6a724f67af70 335 SUPERFAMILY SSF56747 3 331 2.62E-82 T 01-11-2018 AFULGI_00008230 4bc920e6d27596063f6f6a724f67af70 335 Pfam PF01896 DNA primase small subunit 95 272 2.9E-34 T 01-11-2018 IPR002755 DNA primase, small subunit GO:0003896|GO:0006269 Reactome: R-HSA-113501|Reactome: R-HSA-174411|Reactome: R-HSA-174430|Reactome: R-HSA-68952|Reactome: R-HSA-68962|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183 AFULGI_00009240 291322968259fa6fd6dc95844c991ff3 577 Pfam PF13193 AMP-binding enzyme C-terminal domain 482 559 2.0E-22 T 01-11-2018 IPR025110 AMP-binding enzyme, C-terminal domain AFULGI_00009240 291322968259fa6fd6dc95844c991ff3 577 SUPERFAMILY SSF56801 25 571 7.2E-157 T 01-11-2018 AFULGI_00009240 291322968259fa6fd6dc95844c991ff3 577 Pfam PF00501 AMP-binding enzyme 46 472 5.6E-106 T 01-11-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFULGI_00009240 291322968259fa6fd6dc95844c991ff3 577 ProSitePatterns PS00455 Putative AMP-binding domain signature. 227 238 - T 01-11-2018 IPR020845 AMP-binding, conserved site AFULGI_00009240 291322968259fa6fd6dc95844c991ff3 577 Gene3D G3DSA:2.30.38.10 390 466 6.8E-118 T 01-11-2018 AFULGI_00009240 291322968259fa6fd6dc95844c991ff3 577 Gene3D G3DSA:3.40.50.980 68 243 6.8E-118 T 01-11-2018 AFULGI_00009240 291322968259fa6fd6dc95844c991ff3 577 Gene3D G3DSA:3.40.50.980 63 389 6.8E-118 T 01-11-2018 AFULGI_00009240 291322968259fa6fd6dc95844c991ff3 577 Gene3D G3DSA:3.30.300.310 469 574 8.3E-36 T 01-11-2018 AFULGI_00013700 9ec5ec15615c8d725ff304d2fc10eed0 282 Pfam PF08264 Anticodon-binding domain of tRNA 17 162 2.0E-46 T 01-11-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 AFULGI_00013700 9ec5ec15615c8d725ff304d2fc10eed0 282 Gene3D G3DSA:1.10.730.10 2 154 2.0E-48 T 01-11-2018 AFULGI_00013700 9ec5ec15615c8d725ff304d2fc10eed0 282 SUPERFAMILY SSF47323 11 194 1.07E-53 T 01-11-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFULGI_00010360 8959ce20cbbf05eb78a8c1c954c4c3aa 1023 TIGRFAM TIGR04126 PGF_CTERM: PGF-CTERM archaeal protein-sorting signal 998 1023 5.6E-8 T 01-11-2018 IPR026371 PGF-CTERM archaeal protein-sorting signal AFULGI_00001690 ba8931e7ed0d623fd1c39720cfd8a141 382 Gene3D G3DSA:3.40.640.10 13 253 1.4E-154 T 01-11-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFULGI_00001690 ba8931e7ed0d623fd1c39720cfd8a141 382 Hamap MF_00331 Cysteine desulfurase IscS [iscS]. 1 382 48.883 T 01-11-2018 IPR010240 Cysteine desulfurase IscS GO:0030170|GO:0031071|GO:0044571 KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250|Reactome: R-HSA-1362409|Reactome: R-HSA-947581 AFULGI_00001690 ba8931e7ed0d623fd1c39720cfd8a141 382 Gene3D G3DSA:3.90.1150.10 3 363 1.4E-154 T 01-11-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFULGI_00001690 ba8931e7ed0d623fd1c39720cfd8a141 382 SUPERFAMILY SSF53383 2 372 5.91E-102 T 01-11-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFULGI_00001690 ba8931e7ed0d623fd1c39720cfd8a141 382 Pfam PF00266 Aminotransferase class-V 3 362 1.2E-79 T 01-11-2018 IPR000192 Aminotransferase class V domain AFULGI_00001690 ba8931e7ed0d623fd1c39720cfd8a141 382 PIRSF PIRSF005572 1 377 4.4E-131 T 01-11-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 AFULGI_00004380 d617b858e8b0b579ace2d866a7dae9d8 304 SUPERFAMILY SSF48179 185 291 2.98E-23 T 01-11-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AFULGI_00004380 d617b858e8b0b579ace2d866a7dae9d8 304 SUPERFAMILY SSF51735 2 185 9.11E-50 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily AFULGI_00004380 d617b858e8b0b579ace2d866a7dae9d8 304 PIRSF PIRSF000105 1 300 3.5E-72 T 01-11-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 AFULGI_00004380 d617b858e8b0b579ace2d866a7dae9d8 304 Gene3D G3DSA:1.10.1040.10 194 277 3.8E-25 T 01-11-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AFULGI_00004380 d617b858e8b0b579ace2d866a7dae9d8 304 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 4 183 4.7E-60 T 01-11-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 AFULGI_00004380 d617b858e8b0b579ace2d866a7dae9d8 304 Gene3D G3DSA:3.40.50.720 1 188 1.2E-60 T 01-11-2018 AFULGI_00004380 d617b858e8b0b579ace2d866a7dae9d8 304 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 186 277 1.4E-24 T 01-11-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 AFULGI_00000780 3734c081b33900f779d9a594043ecb0d 282 Pfam PF00589 Phage integrase family 87 207 8.3E-11 T 01-11-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 AFULGI_00000780 3734c081b33900f779d9a594043ecb0d 282 SUPERFAMILY SSF56349 19 227 1.03E-20 T 01-11-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 AFULGI_00000780 3734c081b33900f779d9a594043ecb0d 282 Gene3D G3DSA:1.10.443.10 74 223 1.4E-14 T 01-11-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 AFULGI_00009560 d500ae88b944cb8274a054bf20ca979f 335 SUPERFAMILY SSF48179 181 331 3.91E-37 T 01-11-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AFULGI_00009560 d500ae88b944cb8274a054bf20ca979f 335 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 181 327 2.3E-35 T 01-11-2018 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 AFULGI_00009560 d500ae88b944cb8274a054bf20ca979f 335 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 1 330 28.342 T 01-11-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 AFULGI_00009560 d500ae88b944cb8274a054bf20ca979f 335 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 174 198 1.6E-16 T 01-11-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 AFULGI_00009560 d500ae88b944cb8274a054bf20ca979f 335 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 244 261 1.6E-16 T 01-11-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 AFULGI_00009560 d500ae88b944cb8274a054bf20ca979f 335 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 5 22 1.6E-16 T 01-11-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 AFULGI_00009560 d500ae88b944cb8274a054bf20ca979f 335 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 134 154 1.6E-16 T 01-11-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 AFULGI_00009560 d500ae88b944cb8274a054bf20ca979f 335 SUPERFAMILY SSF51735 1 179 2.01E-45 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily AFULGI_00009560 d500ae88b944cb8274a054bf20ca979f 335 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3 160 6.9E-20 T 01-11-2018 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 AFULGI_00009560 d500ae88b944cb8274a054bf20ca979f 335 Gene3D G3DSA:1.10.1040.10 181 335 7.4E-54 T 01-11-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AFULGI_00009560 d500ae88b944cb8274a054bf20ca979f 335 Gene3D G3DSA:3.40.50.720 1 180 1.0E-61 T 01-11-2018 AFULGI_00009560 d500ae88b944cb8274a054bf20ca979f 335 PIRSF PIRSF000114 1 335 1.5E-81 T 01-11-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 AFULGI_00022280 4dc650380af7b0960335542c111e9ff1 254 Gene3D G3DSA:3.30.420.40 1 81 1.3E-6 T 01-11-2018 AFULGI_00022280 4dc650380af7b0960335542c111e9ff1 254 SUPERFAMILY SSF53067 1 249 6.92E-37 T 01-11-2018 AFULGI_00022280 4dc650380af7b0960335542c111e9ff1 254 Pfam PF00480 ROK family 3 247 2.0E-25 T 01-11-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 AFULGI_00022280 4dc650380af7b0960335542c111e9ff1 254 Gene3D G3DSA:3.30.420.40 85 253 2.1E-29 T 01-11-2018 AFULGI_00022280 4dc650380af7b0960335542c111e9ff1 254 ProSitePatterns PS01125 ROK family signature. 108 134 - T 01-11-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 AFULGI_00004330 00b73931c4daffc1ceeb2c7a0c10e154 327 SUPERFAMILY SSF46785 13 79 1.43E-5 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00004330 00b73931c4daffc1ceeb2c7a0c10e154 327 Gene3D G3DSA:1.10.10.2650 22 143 8.1E-41 T 01-11-2018 AFULGI_00004330 00b73931c4daffc1ceeb2c7a0c10e154 327 Pfam PF16864 Dimerisation domain 11 90 8.3E-10 T 01-11-2018 IPR031725 Acetylserotonin O-methyltransferase, dimerisation domain AFULGI_00004330 00b73931c4daffc1ceeb2c7a0c10e154 327 Pfam PF00891 O-methyltransferase 126 223 1.0E-16 T 01-11-2018 IPR001077 O-methyltransferase, family 2 GO:0008171 AFULGI_00004330 00b73931c4daffc1ceeb2c7a0c10e154 327 Gene3D G3DSA:3.40.50.150 144 252 8.1E-41 T 01-11-2018 AFULGI_00004330 00b73931c4daffc1ceeb2c7a0c10e154 327 SUPERFAMILY SSF53335 96 316 4.94E-26 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFULGI_00007560 69ed690df37776271be520599a3f6765 217 Gene3D G3DSA:3.40.50.300 1 217 9.9E-94 T 01-11-2018 AFULGI_00007560 69ed690df37776271be520599a3f6765 217 PRINTS PR00094 Adenylate kinase signature 32 46 1.7E-37 T 01-11-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 AFULGI_00007560 69ed690df37776271be520599a3f6765 217 PRINTS PR00094 Adenylate kinase signature 160 175 1.7E-37 T 01-11-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 AFULGI_00007560 69ed690df37776271be520599a3f6765 217 PRINTS PR00094 Adenylate kinase signature 4 17 1.7E-37 T 01-11-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 AFULGI_00007560 69ed690df37776271be520599a3f6765 217 PRINTS PR00094 Adenylate kinase signature 177 191 1.7E-37 T 01-11-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 AFULGI_00007560 69ed690df37776271be520599a3f6765 217 PRINTS PR00094 Adenylate kinase signature 81 97 1.7E-37 T 01-11-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 AFULGI_00007560 69ed690df37776271be520599a3f6765 217 Hamap MF_00235 Adenylate kinase [adk]. 1 213 56.357 T 01-11-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 AFULGI_00007560 69ed690df37776271be520599a3f6765 217 Pfam PF00406 Adenylate kinase 6 190 9.1E-64 T 01-11-2018 AFULGI_00007560 69ed690df37776271be520599a3f6765 217 Pfam PF05191 Adenylate kinase, active site lid 127 162 1.7E-17 T 01-11-2018 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 AFULGI_00007560 69ed690df37776271be520599a3f6765 217 SUPERFAMILY SSF52540 1 214 7.54E-53 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00007560 69ed690df37776271be520599a3f6765 217 ProSitePatterns PS00113 Adenylate kinase signature. 81 92 - T 01-11-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 AFULGI_00007560 69ed690df37776271be520599a3f6765 217 TIGRFAM TIGR01351 adk: adenylate kinase 2 212 1.1E-90 T 01-11-2018 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 AFULGI_00019420 2713357cea7afc655715c59aead2371b 329 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 4 325 37.197 T 01-11-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 AFULGI_00019420 2713357cea7afc655715c59aead2371b 329 SUPERFAMILY SSF56042 163 322 3.84E-43 T 01-11-2018 IPR036676 PurM-like, C-terminal domain superfamily AFULGI_00019420 2713357cea7afc655715c59aead2371b 329 Pfam PF00586 AIR synthase related protein, N-terminal domain 49 156 2.0E-17 T 01-11-2018 IPR016188 PurM-like, N-terminal domain AFULGI_00019420 2713357cea7afc655715c59aead2371b 329 Gene3D G3DSA:3.30.1330.10 4 162 8.4E-47 T 01-11-2018 IPR036921 PurM-like, N-terminal domain superfamily AFULGI_00019420 2713357cea7afc655715c59aead2371b 329 Pfam PF02769 AIR synthase related protein, C-terminal domain 168 322 3.7E-21 T 01-11-2018 IPR010918 PurM-like, C-terminal domain AFULGI_00019420 2713357cea7afc655715c59aead2371b 329 SUPERFAMILY SSF55326 5 162 5.38E-36 T 01-11-2018 IPR036921 PurM-like, N-terminal domain superfamily AFULGI_00019420 2713357cea7afc655715c59aead2371b 329 Gene3D G3DSA:3.90.650.10 163 327 3.6E-52 T 01-11-2018 IPR036676 PurM-like, C-terminal domain superfamily AFULGI_00019420 2713357cea7afc655715c59aead2371b 329 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 5 315 4.9E-127 T 01-11-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 AFULGI_00006250 c5295d0b8c40d3b0e3690117422221e4 298 Pfam PF06023 CRISPR-associated exonuclease Csa1 1 294 2.4E-74 T 01-11-2018 IPR009260 CRISPR-associated exonuclease Csa1 AFULGI_00006250 c5295d0b8c40d3b0e3690117422221e4 298 TIGRFAM TIGR01896 cas_AF1879: CRISPR-associated protein Cas4/Csa1, subtype I-A/APERN 18 294 8.1E-68 T 01-11-2018 IPR009260 CRISPR-associated exonuclease Csa1 AFULGI_00006250 c5295d0b8c40d3b0e3690117422221e4 298 Gene3D G3DSA:3.90.320.10 191 295 1.3E-5 T 01-11-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal AFULGI_00025990 c98fa1310c77d68eb1a178f7a79938f5 318 Pfam PF01916 Deoxyhypusine synthase 16 302 2.0E-99 T 01-11-2018 IPR002773 Deoxyhypusine synthase GO:0008612 Reactome: R-HSA-204626 AFULGI_00025990 c98fa1310c77d68eb1a178f7a79938f5 318 Hamap MF_00153 Probable deoxyhypusine synthase [dys]. 14 305 42.402 T 01-11-2018 IPR022899 Deoxyhypusine synthase, putative, archaeal GO:0034038 AFULGI_00025990 c98fa1310c77d68eb1a178f7a79938f5 318 Gene3D G3DSA:3.40.910.10 6 312 1.3E-99 T 01-11-2018 IPR036982 Deoxyhypusine synthase superfamily GO:0008612 Reactome: R-HSA-204626 AFULGI_00025990 c98fa1310c77d68eb1a178f7a79938f5 318 TIGRFAM TIGR00321 dhys: deoxyhypusine synthase 13 305 5.7E-129 T 01-11-2018 IPR002773 Deoxyhypusine synthase GO:0008612 Reactome: R-HSA-204626 AFULGI_00025990 c98fa1310c77d68eb1a178f7a79938f5 318 SUPERFAMILY SSF52467 13 308 2.19E-96 T 01-11-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily AFULGI_00015160 d640e3af006dd85407dc4b3e4fab9650 77 SUPERFAMILY SSF54909 4 72 1.18E-18 T 01-11-2018 IPR011008 Dimeric alpha-beta barrel AFULGI_00015160 d640e3af006dd85407dc4b3e4fab9650 77 Pfam PF01037 Lrp/AsnC ligand binding domain 6 72 2.6E-19 T 01-11-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain AFULGI_00015160 d640e3af006dd85407dc4b3e4fab9650 77 Gene3D G3DSA:3.30.70.920 3 73 1.1E-24 T 01-11-2018 AFULGI_00025490 af2b1b69d2304279dac1344dd2f0d654 906 PRINTS PR00980 Alanyl-tRNA synthetase signature 338 354 1.3E-18 T 01-11-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 AFULGI_00025490 af2b1b69d2304279dac1344dd2f0d654 906 PRINTS PR00980 Alanyl-tRNA synthetase signature 208 219 1.3E-18 T 01-11-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 AFULGI_00025490 af2b1b69d2304279dac1344dd2f0d654 906 PRINTS PR00980 Alanyl-tRNA synthetase signature 242 255 1.3E-18 T 01-11-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 AFULGI_00025490 af2b1b69d2304279dac1344dd2f0d654 906 PRINTS PR00980 Alanyl-tRNA synthetase signature 130 141 1.3E-18 T 01-11-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 AFULGI_00025490 af2b1b69d2304279dac1344dd2f0d654 906 PRINTS PR00980 Alanyl-tRNA synthetase signature 362 375 1.3E-18 T 01-11-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 AFULGI_00025490 af2b1b69d2304279dac1344dd2f0d654 906 Gene3D G3DSA:3.30.980.10 598 734 3.2E-47 T 01-11-2018 AFULGI_00025490 af2b1b69d2304279dac1344dd2f0d654 906 Pfam PF02272 DHHA1 domain 769 896 5.8E-18 T 01-11-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 AFULGI_00025490 af2b1b69d2304279dac1344dd2f0d654 906 Pfam PF01411 tRNA synthetases class II (A) 64 591 5.1E-149 T 01-11-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 AFULGI_00025490 af2b1b69d2304279dac1344dd2f0d654 906 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 64 883 1.7E-272 T 01-11-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 AFULGI_00025490 af2b1b69d2304279dac1344dd2f0d654 906 TIGRFAM TIGR03683 A-tRNA_syn_arch: alanine--tRNA ligase 6 901 0.0 T 01-11-2018 IPR022429 Alanine-tRNA ligase, archaea GO:0000166|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 AFULGI_00025490 af2b1b69d2304279dac1344dd2f0d654 906 SUPERFAMILY SSF50447 502 587 2.08E-17 T 01-11-2018 IPR009000 Translation protein, beta-barrel domain superfamily AFULGI_00025490 af2b1b69d2304279dac1344dd2f0d654 906 SUPERFAMILY SSF55681 61 261 2.15E-55 T 01-11-2018 AFULGI_00025490 af2b1b69d2304279dac1344dd2f0d654 906 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 691 732 3.0E-14 T 01-11-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 AFULGI_00025490 af2b1b69d2304279dac1344dd2f0d654 906 Gene3D G3DSA:3.30.930.10 1 257 7.4E-117 T 01-11-2018 AFULGI_00025490 af2b1b69d2304279dac1344dd2f0d654 906 Gene3D G3DSA:2.40.30.130 491 588 8.5E-35 T 01-11-2018 AFULGI_00025490 af2b1b69d2304279dac1344dd2f0d654 906 SUPERFAMILY SSF55186 588 745 8.37E-45 T 01-11-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 AFULGI_00025490 af2b1b69d2304279dac1344dd2f0d654 906 SUPERFAMILY SSF101353 309 517 1.12E-41 T 01-11-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 AFULGI_00025490 af2b1b69d2304279dac1344dd2f0d654 906 Gene3D G3DSA:3.30.54.20 660 714 3.2E-47 T 01-11-2018 AFULGI_00025490 af2b1b69d2304279dac1344dd2f0d654 906 SMART SM00863 691 733 3.6E-18 T 01-11-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 AFULGI_00025490 af2b1b69d2304279dac1344dd2f0d654 906 Hamap MF_00036_A Alanine--tRNA ligase [alaS]. 7 898 23.335 T 01-11-2018 IPR022429 Alanine-tRNA ligase, archaea GO:0000166|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 AFULGI_00025490 af2b1b69d2304279dac1344dd2f0d654 906 Gene3D G3DSA:3.10.310.40 801 906 7.0E-42 T 01-11-2018 AFULGI_00009670 c859357b8d159e71ca79e4d29f441b41 53 Pfam PF00301 Rubredoxin 3 49 1.6E-26 T 01-11-2018 IPR024935 Rubredoxin domain GO:0005506 AFULGI_00009670 c859357b8d159e71ca79e4d29f441b41 53 PIRSF PIRSF000071 1 53 7.2E-30 T 01-11-2018 IPR024922 Rubredoxin GO:0005506|GO:0009055 AFULGI_00009670 c859357b8d159e71ca79e4d29f441b41 53 SUPERFAMILY SSF57802 1 53 5.72E-25 T 01-11-2018 AFULGI_00009670 c859357b8d159e71ca79e4d29f441b41 53 ProSitePatterns PS00202 Rubredoxin signature. 33 43 - T 01-11-2018 IPR018527 Rubredoxin, iron-binding site GO:0046872 AFULGI_00009670 c859357b8d159e71ca79e4d29f441b41 53 PRINTS PR00163 Rubredoxin signature 3 19 7.5E-14 T 01-11-2018 IPR024935 Rubredoxin domain GO:0005506 AFULGI_00009670 c859357b8d159e71ca79e4d29f441b41 53 PRINTS PR00163 Rubredoxin signature 33 49 7.5E-14 T 01-11-2018 IPR024935 Rubredoxin domain GO:0005506 AFULGI_00009670 c859357b8d159e71ca79e4d29f441b41 53 Gene3D G3DSA:2.20.28.10 1 53 4.4E-30 T 01-11-2018 AFULGI_00018070 7724ccacf90013e8f33f01a805353a59 216 Hamap MF_00299 Probable RNA 2'-phosphotransferase [kptA]. 29 200 34.06 T 01-11-2018 IPR022928 RNA 2'-phosphotransferase KptA, putative GO:0016773 AFULGI_00018070 7724ccacf90013e8f33f01a805353a59 216 SUPERFAMILY SSF56399 32 205 1.01E-47 T 01-11-2018 AFULGI_00018070 7724ccacf90013e8f33f01a805353a59 216 Gene3D G3DSA:3.20.170.30 120 208 9.2E-27 T 01-11-2018 AFULGI_00018070 7724ccacf90013e8f33f01a805353a59 216 Pfam PF01885 RNA 2'-phosphotransferase, Tpt1 / KptA family 30 185 1.1E-29 T 01-11-2018 IPR002745 Phosphotransferase KptA/Tpt1 GO:0006388|GO:0016772 AFULGI_00018070 7724ccacf90013e8f33f01a805353a59 216 Gene3D G3DSA:1.10.10.970 29 99 5.6E-21 T 01-11-2018 AFULGI_00026000 537ae5130335837585eee3daf3cc840a 186 SUPERFAMILY SSF56271 28 185 2.14E-51 T 01-11-2018 IPR016104 Pyruvoyl-dependent histidine/arginine decarboxylase GO:0006520|GO:0016831 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 AFULGI_00026000 537ae5130335837585eee3daf3cc840a 186 PIRSF PIRSF005216 28 186 9.8E-61 T 01-11-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 AFULGI_00026000 537ae5130335837585eee3daf3cc840a 186 Hamap MF_01404 Pyruvoyl-dependent arginine decarboxylase [pdaD]. 1 186 65.545 T 01-11-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 AFULGI_00026000 537ae5130335837585eee3daf3cc840a 186 TIGRFAM TIGR00286 TIGR00286: arginine decarboxylase, pyruvoyl-dependent 30 186 1.8E-74 T 01-11-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 AFULGI_00026000 537ae5130335837585eee3daf3cc840a 186 ProDom PD010449 DECARBOXYLASE PYRUVOYL-DEPENDENT ARGININE SUBUNIT ALPHA CONTAINS: BETA PVLARGDC LYA DECARBOX 31 169 4.0E-76 T 01-11-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 AFULGI_00026000 537ae5130335837585eee3daf3cc840a 186 Pfam PF01862 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) 32 185 6.9E-55 T 01-11-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 AFULGI_00026000 537ae5130335837585eee3daf3cc840a 186 Gene3D G3DSA:3.50.20.10 24 185 3.5E-46 T 01-11-2018 IPR016105 Pyruvoyl-dependent histidine/arginine decarboxylase, 3-layer sandwich domain GO:0006520|GO:0016831 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 AFULGI_00024800 11012d5427a24963be3ea4998da4f793 243 Gene3D G3DSA:3.40.1190.20 1 239 3.3E-67 T 01-11-2018 IPR029056 Ribokinase-like AFULGI_00024800 11012d5427a24963be3ea4998da4f793 243 SUPERFAMILY SSF53613 1 236 2.81E-55 T 01-11-2018 IPR029056 Ribokinase-like AFULGI_00024800 11012d5427a24963be3ea4998da4f793 243 Pfam PF08543 Phosphomethylpyrimidine kinase 11 236 2.1E-65 T 01-11-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 AFULGI_00021390 513b52f058d42d0c6dd87be982cd0cdc 281 TIGRFAM TIGR01896 cas_AF1879: CRISPR-associated protein Cas4/Csa1, subtype I-A/APERN 21 280 4.2E-61 T 01-11-2018 IPR009260 CRISPR-associated exonuclease Csa1 AFULGI_00021390 513b52f058d42d0c6dd87be982cd0cdc 281 PIRSF PIRSF009226 6 281 2.6E-110 T 01-11-2018 IPR009260 CRISPR-associated exonuclease Csa1 AFULGI_00021390 513b52f058d42d0c6dd87be982cd0cdc 281 Pfam PF06023 CRISPR-associated exonuclease Csa1 1 280 2.1E-111 T 01-11-2018 IPR009260 CRISPR-associated exonuclease Csa1 AFULGI_00026110 97d11f89088264ea29853042efe8ae93 60 Pfam PF12802 MarR family 7 48 5.2E-8 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFULGI_00026110 97d11f89088264ea29853042efe8ae93 60 SUPERFAMILY SSF46785 3 58 8.63E-15 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00026110 97d11f89088264ea29853042efe8ae93 60 Gene3D G3DSA:1.10.10.10 1 58 9.0E-15 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00009160 36938d57814423e0d48d69aaa3c7dba9 169 Gene3D G3DSA:2.30.110.10 1 169 2.1E-43 T 01-11-2018 IPR012349 FMN-binding split barrel GO:0048037 AFULGI_00009160 36938d57814423e0d48d69aaa3c7dba9 169 Pfam PF01613 Flavin reductase like domain 8 150 1.0E-22 T 01-11-2018 IPR002563 Flavin reductase like domain GO:0010181 AFULGI_00009160 36938d57814423e0d48d69aaa3c7dba9 169 SUPERFAMILY SSF50475 5 151 4.66E-35 T 01-11-2018 AFULGI_00009160 36938d57814423e0d48d69aaa3c7dba9 169 SMART SM00903 6 152 3.0E-23 T 01-11-2018 IPR002563 Flavin reductase like domain GO:0010181 AFULGI_00001080 56902bf6e56457b5a8dd0f68c92363ea 299 Pfam PF03444 Winged helix-turn-helix transcription repressor, HrcA DNA-binding 5 82 2.4E-37 T 01-11-2018 IPR005104 Winged helix-turn-helix transcription repressor, HrcA DNA-binding domain GO:0003677|GO:0006355 AFULGI_00001080 56902bf6e56457b5a8dd0f68c92363ea 299 SUPERFAMILY SSF54631 167 296 2.15E-27 T 01-11-2018 AFULGI_00001080 56902bf6e56457b5a8dd0f68c92363ea 299 Gene3D G3DSA:1.10.10.10 12 103 1.2E-8 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00001080 56902bf6e56457b5a8dd0f68c92363ea 299 Gene3D G3DSA:3.10.580.10 173 296 2.5E-28 T 01-11-2018 AFULGI_00001080 56902bf6e56457b5a8dd0f68c92363ea 299 PIRSF PIRSF005063 3 299 4.8E-121 T 01-11-2018 IPR016436 Uncharacterised conserved protein UCP005063, CBS-type AFULGI_00001080 56902bf6e56457b5a8dd0f68c92363ea 299 SUPERFAMILY SSF46785 14 134 1.1E-14 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00001080 56902bf6e56457b5a8dd0f68c92363ea 299 SMART SM00116 184 231 0.0022 T 01-11-2018 IPR000644 CBS domain AFULGI_00001080 56902bf6e56457b5a8dd0f68c92363ea 299 SMART SM00116 246 293 4.3E-7 T 01-11-2018 IPR000644 CBS domain AFULGI_00001080 56902bf6e56457b5a8dd0f68c92363ea 299 Pfam PF00571 CBS domain 177 231 8.9E-8 T 01-11-2018 IPR000644 CBS domain AFULGI_00001080 56902bf6e56457b5a8dd0f68c92363ea 299 Pfam PF00571 CBS domain 239 293 6.8E-12 T 01-11-2018 IPR000644 CBS domain AFULGI_00014600 d2bc856b59fab2c09eb3bc4a24a19df7 65 Pfam PF00301 Rubredoxin 14 60 1.5E-26 T 01-11-2018 IPR024935 Rubredoxin domain GO:0005506 AFULGI_00014600 d2bc856b59fab2c09eb3bc4a24a19df7 65 Gene3D G3DSA:2.20.28.10 12 64 5.7E-30 T 01-11-2018 AFULGI_00014600 d2bc856b59fab2c09eb3bc4a24a19df7 65 ProSitePatterns PS00202 Rubredoxin signature. 44 54 - T 01-11-2018 IPR018527 Rubredoxin, iron-binding site GO:0046872 AFULGI_00014600 d2bc856b59fab2c09eb3bc4a24a19df7 65 PRINTS PR00163 Rubredoxin signature 44 60 8.0E-14 T 01-11-2018 IPR024935 Rubredoxin domain GO:0005506 AFULGI_00014600 d2bc856b59fab2c09eb3bc4a24a19df7 65 PRINTS PR00163 Rubredoxin signature 14 30 8.0E-14 T 01-11-2018 IPR024935 Rubredoxin domain GO:0005506 AFULGI_00014600 d2bc856b59fab2c09eb3bc4a24a19df7 65 PIRSF PIRSF000071 11 65 1.4E-29 T 01-11-2018 IPR024922 Rubredoxin GO:0005506|GO:0009055 AFULGI_00014600 d2bc856b59fab2c09eb3bc4a24a19df7 65 SUPERFAMILY SSF57802 11 64 3.87E-25 T 01-11-2018 AFULGI_00020140 343687f7617b978de678aa61165d7050 474 Gene3D G3DSA:3.40.50.1820 21 237 3.2E-73 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold AFULGI_00020140 343687f7617b978de678aa61165d7050 474 Pfam PF00561 alpha/beta hydrolase fold 24 157 3.9E-6 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 AFULGI_00020140 343687f7617b978de678aa61165d7050 474 SUPERFAMILY SSF53474 23 172 6.61E-19 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold AFULGI_00020140 343687f7617b978de678aa61165d7050 474 Gene3D G3DSA:2.60.40.2200 332 474 1.5E-69 T 01-11-2018 AFULGI_00020140 343687f7617b978de678aa61165d7050 474 Gene3D G3DSA:2.60.40.2190 238 331 1.1E-63 T 01-11-2018 AFULGI_00002740 57efc1bf6f399cf9e692162c531c3b8c 99 Gene3D G3DSA:1.10.10.10 4 93 8.0E-7 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00002740 57efc1bf6f399cf9e692162c531c3b8c 99 SUPERFAMILY SSF46785 13 78 1.77E-11 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00003400 d47ffbbb693ab4619863a0f5df28ec85 48 Gene3D G3DSA:2.20.28.10 2 36 4.7E-15 T 01-11-2018 AFULGI_00003400 d47ffbbb693ab4619863a0f5df28ec85 48 SUPERFAMILY SSF57802 2 35 3.37E-10 T 01-11-2018 AFULGI_00004210 97502a2e72ce2d1ce15ad28433e2a2d9 190 Pfam PF11655 Protein of unknown function (DUF2589) 14 177 1.2E-43 T 01-11-2018 IPR024510 Protein of unknown function DUF2589 AFULGI_00004210 97502a2e72ce2d1ce15ad28433e2a2d9 190 ProDom PD104924 XAC1607 AF0417 9 189 6.0E-89 T 01-11-2018 AFULGI_00020840 3ba027854fe3215f9fd055a5d58c3093 410 Gene3D G3DSA:1.10.645.20 35 410 5.4E-120 T 01-11-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFULGI_00020840 3ba027854fe3215f9fd055a5d58c3093 410 SUPERFAMILY SSF56762 49 410 2.88E-99 T 01-11-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFULGI_00020840 3ba027854fe3215f9fd055a5d58c3093 410 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 150 410 2.9E-85 T 01-11-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFULGI_00020950 cba520ac56365bf23ee6e2958ce81e40 274 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 18 100 4.1E-21 T 01-11-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 AFULGI_00020950 cba520ac56365bf23ee6e2958ce81e40 274 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 102 271 1.7E-62 T 01-11-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 Reactome: R-HSA-196807 AFULGI_00020950 cba520ac56365bf23ee6e2958ce81e40 274 SUPERFAMILY SSF51690 102 271 4.71E-54 T 01-11-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 AFULGI_00020950 cba520ac56365bf23ee6e2958ce81e40 274 Gene3D G3DSA:3.20.20.70 118 262 1.6E-90 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFULGI_00020950 cba520ac56365bf23ee6e2958ce81e40 274 Gene3D G3DSA:3.90.1170.20 11 270 1.6E-90 T 01-11-2018 IPR037128 Quinolinate phosphoribosyl transferase, N-terminal domain superfamily GO:0016763 Reactome: R-HSA-196807 AFULGI_00020950 cba520ac56365bf23ee6e2958ce81e40 274 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 9 271 3.2E-94 T 01-11-2018 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 AFULGI_00020950 cba520ac56365bf23ee6e2958ce81e40 274 SUPERFAMILY SSF54675 3 101 3.24E-23 T 01-11-2018 AFULGI_00020950 cba520ac56365bf23ee6e2958ce81e40 274 PIRSF PIRSF006250 1 274 1.2E-105 T 01-11-2018 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 AFULGI_00013020 5dcfdcb016fcfbe587539638982d2ca3 706 Pfam PF01568 Molydopterin dinucleotide binding domain 583 694 3.3E-30 T 01-11-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 AFULGI_00013020 5dcfdcb016fcfbe587539638982d2ca3 706 Gene3D G3DSA:3.40.50.740 61 509 1.7E-145 T 01-11-2018 AFULGI_00013020 5dcfdcb016fcfbe587539638982d2ca3 706 SUPERFAMILY SSF50692 533 701 1.6E-42 T 01-11-2018 IPR009010 Aspartate decarboxylase-like domain superfamily AFULGI_00013020 5dcfdcb016fcfbe587539638982d2ca3 706 Gene3D G3DSA:2.20.25.90 1 60 1.6E-17 T 01-11-2018 AFULGI_00013020 5dcfdcb016fcfbe587539638982d2ca3 706 SMART SM00926 3 56 6.7E-13 T 01-11-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFULGI_00013020 5dcfdcb016fcfbe587539638982d2ca3 706 Pfam PF00384 Molybdopterin oxidoreductase 382 479 1.3E-17 T 01-11-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFULGI_00013020 5dcfdcb016fcfbe587539638982d2ca3 706 Pfam PF00384 Molybdopterin oxidoreductase 59 329 2.8E-43 T 01-11-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFULGI_00013020 5dcfdcb016fcfbe587539638982d2ca3 706 SUPERFAMILY SSF53706 5 581 2.62E-156 T 01-11-2018 AFULGI_00013020 5dcfdcb016fcfbe587539638982d2ca3 706 Gene3D G3DSA:3.40.228.10 143 337 1.7E-145 T 01-11-2018 AFULGI_00013020 5dcfdcb016fcfbe587539638982d2ca3 706 Gene3D G3DSA:2.40.40.20 550 702 2.9E-51 T 01-11-2018 AFULGI_00013020 5dcfdcb016fcfbe587539638982d2ca3 706 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 4 56 4.2E-13 T 01-11-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFULGI_00023180 86d5a51c7720254a60cc0d974effe701 126 Gene3D G3DSA:2.60.120.460 1 126 1.2E-48 T 01-11-2018 IPR035917 YjbQ-like superfamily AFULGI_00023180 86d5a51c7720254a60cc0d974effe701 126 SUPERFAMILY SSF111038 2 125 8.24E-44 T 01-11-2018 IPR035917 YjbQ-like superfamily AFULGI_00023180 86d5a51c7720254a60cc0d974effe701 126 Pfam PF01894 Uncharacterised protein family UPF0047 15 124 7.3E-38 T 01-11-2018 IPR001602 Uncharacterised protein family UPF0047 AFULGI_00023180 86d5a51c7720254a60cc0d974effe701 126 TIGRFAM TIGR00149 TIGR00149_YjbQ: secondary thiamine-phosphate synthase enzyme 1 125 4.0E-52 T 01-11-2018 IPR001602 Uncharacterised protein family UPF0047 AFULGI_00023180 86d5a51c7720254a60cc0d974effe701 126 PIRSF PIRSF004681 1 126 8.4E-40 T 01-11-2018 IPR001602 Uncharacterised protein family UPF0047 AFULGI_00023180 86d5a51c7720254a60cc0d974effe701 126 ProSitePatterns PS01314 Uncharacterized protein family UPF0047 signature. 90 108 - T 01-11-2018 IPR001602 Uncharacterised protein family UPF0047 AFULGI_00003470 c11b3b54e368975be7fb0196e942ed69 126 SUPERFAMILY SSF69118 17 122 2.09E-20 T 01-11-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 AFULGI_00003470 c11b3b54e368975be7fb0196e942ed69 126 Gene3D G3DSA:1.20.1290.10 2 122 2.7E-20 T 01-11-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 AFULGI_00003470 c11b3b54e368975be7fb0196e942ed69 126 Pfam PF02627 Carboxymuconolactone decarboxylase family 37 109 2.0E-11 T 01-11-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 AFULGI_00022390 7bf955c61ba1c9060cdf6ff7b9f7341e 231 Pfam PF01909 Nucleotidyltransferase domain 29 97 2.5E-7 T 01-11-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 AFULGI_00022390 7bf955c61ba1c9060cdf6ff7b9f7341e 231 Gene3D G3DSA:3.30.460.10 11 97 3.5E-6 T 01-11-2018 AFULGI_00022390 7bf955c61ba1c9060cdf6ff7b9f7341e 231 PIRSF PIRSF005928 8 231 4.5E-113 T 01-11-2018 IPR009185 Predicted nucleotidyltransferase AFULGI_00022390 7bf955c61ba1c9060cdf6ff7b9f7341e 231 SUPERFAMILY SSF81301 16 71 4.36E-8 T 01-11-2018 AFULGI_00003710 de365c3eda7bd626092e292d1d0be140 198 SMART SM00478 46 193 7.7E-17 T 01-11-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 AFULGI_00003710 de365c3eda7bd626092e292d1d0be140 198 PIRSF PIRSF005954 1 198 5.7E-74 T 01-11-2018 IPR012092 8-oxoguanine DNA glycosylase/DNA lyase, thermostable GO:0003906|GO:0006281|GO:0016799 AFULGI_00003710 de365c3eda7bd626092e292d1d0be140 198 Gene3D G3DSA:1.10.340.30 34 134 1.9E-49 T 01-11-2018 AFULGI_00003710 de365c3eda7bd626092e292d1d0be140 198 SUPERFAMILY SSF48150 31 179 7.33E-20 T 01-11-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 AFULGI_00003710 de365c3eda7bd626092e292d1d0be140 198 Hamap MF_00241 Probable N-glycosylase/DNA lyase [ogg]. 6 198 29.336 T 01-11-2018 IPR012092 8-oxoguanine DNA glycosylase/DNA lyase, thermostable GO:0003906|GO:0006281|GO:0016799 AFULGI_00003710 de365c3eda7bd626092e292d1d0be140 198 Gene3D G3DSA:1.10.1670.10 135 198 1.9E-49 T 01-11-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 AFULGI_00015460 bbcc4bce374b700e43378e20c179992d 173 SUPERFAMILY SSF109604 7 172 1.13E-33 T 01-11-2018 AFULGI_00015460 bbcc4bce374b700e43378e20c179992d 173 Gene3D G3DSA:1.10.3210.10 1 173 2.3E-66 T 01-11-2018 AFULGI_00015460 bbcc4bce374b700e43378e20c179992d 173 Pfam PF13023 HD domain 17 96 1.5E-16 T 01-11-2018 IPR006674 HD domain AFULGI_00015460 bbcc4bce374b700e43378e20c179992d 173 SMART SM00471 35 138 1.2E-9 T 01-11-2018 IPR003607 HD/PDEase domain AFULGI_00025400 72bb6c9dffdaa855a18c1a96a5dcfdc6 177 Gene3D G3DSA:1.10.15.40 108 163 3.6E-20 T 01-11-2018 AFULGI_00025400 72bb6c9dffdaa855a18c1a96a5dcfdc6 177 Pfam PF04060 Putative Fe-S cluster 118 150 1.3E-14 T 01-11-2018 IPR007202 4Fe-4S domain GO:0051536 AFULGI_00001910 6d36c3ed08588f6ae4aa0128e951a00c 182 Gene3D G3DSA:2.40.50.140 56 141 2.3E-20 T 01-11-2018 AFULGI_00001910 6d36c3ed08588f6ae4aa0128e951a00c 182 Hamap MF_00975 Exosome complex component Csl4 [csl4]. 6 179 25.253 T 01-11-2018 IPR030850 Exosome complex component Csl4, archaea GO:0000178|GO:0006396 AFULGI_00001910 6d36c3ed08588f6ae4aa0128e951a00c 182 Gene3D G3DSA:2.20.70.10 142 175 2.9E-21 T 01-11-2018 AFULGI_00001910 6d36c3ed08588f6ae4aa0128e951a00c 182 Gene3D G3DSA:2.40.50.100 4 55 3.5E-25 T 01-11-2018 AFULGI_00001910 6d36c3ed08588f6ae4aa0128e951a00c 182 Pfam PF10447 Exosome component EXOSC1/CSL4 55 175 1.7E-26 T 01-11-2018 IPR019495 Exosome complex component CSL4, C-terminal GO:0000178|GO:0003723 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 AFULGI_00001910 6d36c3ed08588f6ae4aa0128e951a00c 182 Pfam PF14382 Exosome complex exonuclease RRP4 N-terminal region 6 42 8.6E-12 T 01-11-2018 IPR025721 Exosome complex component, N-terminal domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 AFULGI_00001910 6d36c3ed08588f6ae4aa0128e951a00c 182 SUPERFAMILY SSF50249 57 173 1.11E-19 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold AFULGI_00001910 6d36c3ed08588f6ae4aa0128e951a00c 182 SUPERFAMILY SSF110324 6 45 2.09E-10 T 01-11-2018 AFULGI_00001910 6d36c3ed08588f6ae4aa0128e951a00c 182 SMART SM00316 59 135 0.0081 T 01-11-2018 IPR022967 RNA-binding domain, S1 AFULGI_00005020 180833c1905003d53b2ea09918477b41 259 Pfam PF01138 3' exoribonuclease family, domain 1 31 166 2.9E-29 T 01-11-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 AFULGI_00005020 180833c1905003d53b2ea09918477b41 259 Hamap MF_00622 Exosome complex component Rrp42 [rrp42]. 2 259 43.776 T 01-11-2018 IPR020869 Exosome complex component Rrp42, archaea GO:0000178|GO:0006401 AFULGI_00005020 180833c1905003d53b2ea09918477b41 259 SUPERFAMILY SSF54211 6 204 3.14E-52 T 01-11-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFULGI_00005020 180833c1905003d53b2ea09918477b41 259 SUPERFAMILY SSF55666 179 256 9.12E-20 T 01-11-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 AFULGI_00005020 180833c1905003d53b2ea09918477b41 259 Gene3D G3DSA:3.30.230.70 7 259 6.6E-83 T 01-11-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 AFULGI_00005020 180833c1905003d53b2ea09918477b41 259 Pfam PF03725 3' exoribonuclease family, domain 2 182 245 3.1E-12 T 01-11-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 AFULGI_00017180 b4d75a0028d73618a2112e2a53d20ce6 176 SUPERFAMILY SSF55874 86 174 5.37E-16 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFULGI_00017180 b4d75a0028d73618a2112e2a53d20ce6 176 Gene3D G3DSA:3.30.565.10 71 176 3.0E-15 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFULGI_00017180 b4d75a0028d73618a2112e2a53d20ce6 176 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 112 172 6.3E-8 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFULGI_00013500 39fcf2f79632ac96a258fcc9a4fb9336 480 SUPERFAMILY SSF89000 298 447 9.02E-54 T 01-11-2018 AFULGI_00013500 39fcf2f79632ac96a258fcc9a4fb9336 480 Gene3D G3DSA:3.20.20.70 1 454 1.1E-174 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFULGI_00013500 39fcf2f79632ac96a258fcc9a4fb9336 480 Pfam PF00682 HMGL-like 3 269 1.3E-48 T 01-11-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 AFULGI_00013500 39fcf2f79632ac96a258fcc9a4fb9336 480 SUPERFAMILY SSF51569 2 301 6.59E-93 T 01-11-2018 AFULGI_00013500 39fcf2f79632ac96a258fcc9a4fb9336 480 TIGRFAM TIGR01108 oadA: oxaloacetate decarboxylase alpha subunit 6 479 6.0E-247 T 01-11-2018 IPR005776 Oxaloacetate decarboxylase, alpha subunit GO:0006814|GO:0008948 AFULGI_00013500 39fcf2f79632ac96a258fcc9a4fb9336 480 Pfam PF02436 Conserved carboxylase domain 293 474 1.5E-57 T 01-11-2018 IPR003379 Carboxylase, conserved domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 AFULGI_00024750 76c30cc1a086506734ae2f689868a684 119 Pfam PF03551 Transcriptional regulator PadR-like family 24 95 2.4E-24 T 01-11-2018 IPR005149 Transcription regulator PadR, N-terminal AFULGI_00024750 76c30cc1a086506734ae2f689868a684 119 SUPERFAMILY SSF46785 13 110 8.91E-25 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00024750 76c30cc1a086506734ae2f689868a684 119 Gene3D G3DSA:1.10.10.10 8 118 1.1E-29 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00003190 a0dd5f6b0e6f933a474e0d5126194e75 165 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 2 139 1.0E-9 T 01-11-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 AFULGI_00003190 a0dd5f6b0e6f933a474e0d5126194e75 165 SUPERFAMILY SSF51182 2 138 1.03E-28 T 01-11-2018 IPR011051 RmlC-like cupin domain superfamily AFULGI_00003190 a0dd5f6b0e6f933a474e0d5126194e75 165 Gene3D G3DSA:2.60.120.10 1 142 1.7E-36 T 01-11-2018 IPR014710 RmlC-like jelly roll fold AFULGI_00003190 a0dd5f6b0e6f933a474e0d5126194e75 165 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 2 139 1.4E-10 T 01-11-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 AFULGI_00011530 f7d508e9c477887ba841e2bc2a78b6ea 194 Hamap MF_00587 tRNA (pseudouridine(54)-N(1))-methyltransferase [trmY]. 1 193 38.895 T 01-11-2018 IPR007158 tRNA (pseudouridine(54)-N(1))-methyltransferase, TrmY GO:0008175 AFULGI_00011530 f7d508e9c477887ba841e2bc2a78b6ea 194 Pfam PF04013 Putative SAM-dependent RNA methyltransferase 1 194 8.0E-88 T 01-11-2018 IPR007158 tRNA (pseudouridine(54)-N(1))-methyltransferase, TrmY GO:0008175 AFULGI_00011530 f7d508e9c477887ba841e2bc2a78b6ea 194 SUPERFAMILY SSF75217 2 192 3.84E-65 T 01-11-2018 IPR029028 Alpha/beta knot methyltransferases AFULGI_00011530 f7d508e9c477887ba841e2bc2a78b6ea 194 Gene3D G3DSA:3.40.1280.10 1 194 4.3E-85 T 01-11-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal AFULGI_00025310 d53f4eb75cf6b96fb596c8db103c5688 545 Gene3D G3DSA:3.50.7.10 218 369 7.6E-212 T 01-11-2018 IPR027409 GroEL-like apical domain superfamily AFULGI_00025310 d53f4eb75cf6b96fb596c8db103c5688 545 ProSitePatterns PS00750 Chaperonins TCP-1 signature 1. 40 52 - T 01-11-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 AFULGI_00025310 d53f4eb75cf6b96fb596c8db103c5688 545 ProSitePatterns PS00751 Chaperonins TCP-1 signature 2. 61 77 - T 01-11-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 AFULGI_00025310 d53f4eb75cf6b96fb596c8db103c5688 545 Pfam PF00118 TCP-1/cpn60 chaperonin family 35 525 1.3E-189 T 01-11-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 AFULGI_00025310 d53f4eb75cf6b96fb596c8db103c5688 545 ProSitePatterns PS00995 Chaperonins TCP-1 signature 3. 89 97 - T 01-11-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 AFULGI_00025310 d53f4eb75cf6b96fb596c8db103c5688 545 SUPERFAMILY SSF52029 212 378 8.63E-62 T 01-11-2018 IPR027409 GroEL-like apical domain superfamily AFULGI_00025310 d53f4eb75cf6b96fb596c8db103c5688 545 TIGRFAM TIGR02339 thermosome_arch: thermosome, various subunits, archaeal 8 525 4.6E-261 T 01-11-2018 IPR012714 Thermosome, archaeal GO:0005524|GO:0006457|GO:0051082 AFULGI_00025310 d53f4eb75cf6b96fb596c8db103c5688 545 Gene3D G3DSA:1.10.560.10 28 522 7.6E-212 T 01-11-2018 IPR027413 GroEL-like equatorial domain superfamily AFULGI_00025310 d53f4eb75cf6b96fb596c8db103c5688 545 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 407 419 1.8E-37 T 01-11-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 AFULGI_00025310 d53f4eb75cf6b96fb596c8db103c5688 545 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 89 108 1.8E-37 T 01-11-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 AFULGI_00025310 d53f4eb75cf6b96fb596c8db103c5688 545 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 59 77 1.8E-37 T 01-11-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 AFULGI_00025310 d53f4eb75cf6b96fb596c8db103c5688 545 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 37 53 1.8E-37 T 01-11-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 AFULGI_00025310 d53f4eb75cf6b96fb596c8db103c5688 545 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 373 395 1.8E-37 T 01-11-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 AFULGI_00025310 d53f4eb75cf6b96fb596c8db103c5688 545 SUPERFAMILY SSF48592 17 524 4.32E-97 T 01-11-2018 IPR027413 GroEL-like equatorial domain superfamily AFULGI_00025310 d53f4eb75cf6b96fb596c8db103c5688 545 Gene3D G3DSA:3.30.260.10 147 405 7.6E-212 T 01-11-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily AFULGI_00025310 d53f4eb75cf6b96fb596c8db103c5688 545 SUPERFAMILY SSF54849 147 404 2.75E-29 T 01-11-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily AFULGI_00007660 0c40de457a7d21dc5e7c7afb831b1dab 284 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 106 126 - T 01-11-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 AFULGI_00007660 0c40de457a7d21dc5e7c7afb831b1dab 284 Gene3D G3DSA:1.10.12.10 211 264 9.8E-11 T 01-11-2018 IPR014748 Enoyl-CoA hydratase, C-terminal AFULGI_00007660 0c40de457a7d21dc5e7c7afb831b1dab 284 Gene3D G3DSA:3.90.226.10 1 206 1.3E-68 T 01-11-2018 AFULGI_00007660 0c40de457a7d21dc5e7c7afb831b1dab 284 Pfam PF00378 Enoyl-CoA hydratase/isomerase 12 264 1.0E-52 T 01-11-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 AFULGI_00007660 0c40de457a7d21dc5e7c7afb831b1dab 284 SUPERFAMILY SSF52096 1 264 1.2E-79 T 01-11-2018 IPR029045 ClpP/crotonase-like domain superfamily AFULGI_00010390 1cc9edbafb6d593c3dbaf862947ae6c3 482 SUPERFAMILY SSF54368 5 104 6.28E-26 T 01-11-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 AFULGI_00010390 1cc9edbafb6d593c3dbaf862947ae6c3 482 Gene3D G3DSA:3.30.590.10 110 469 1.7E-118 T 01-11-2018 AFULGI_00010390 1cc9edbafb6d593c3dbaf862947ae6c3 482 Gene3D G3DSA:3.10.20.70 2 107 4.0E-26 T 01-11-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 AFULGI_00010390 1cc9edbafb6d593c3dbaf862947ae6c3 482 SUPERFAMILY SSF55931 109 481 1.77E-117 T 01-11-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 AFULGI_00010390 1cc9edbafb6d593c3dbaf862947ae6c3 482 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 6 481 1.3E-200 T 01-11-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 AFULGI_00010390 1cc9edbafb6d593c3dbaf862947ae6c3 482 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 267 282 - T 01-11-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 AFULGI_00010390 1cc9edbafb6d593c3dbaf862947ae6c3 482 Pfam PF00120 Glutamine synthetase, catalytic domain 108 479 3.7E-132 T 01-11-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 AFULGI_00010390 1cc9edbafb6d593c3dbaf862947ae6c3 482 SMART SM01230 107 393 3.3E-115 T 01-11-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 AFULGI_00010390 1cc9edbafb6d593c3dbaf862947ae6c3 482 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 15 99 4.3E-22 T 01-11-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 AFULGI_00014090 154e12ae9980251ff3aaf47e810c92b2 223 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 41 56 3.7E-5 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFULGI_00014090 154e12ae9980251ff3aaf47e810c92b2 223 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 9 24 3.7E-5 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFULGI_00014090 154e12ae9980251ff3aaf47e810c92b2 223 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 56 71 3.7E-5 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFULGI_00014090 154e12ae9980251ff3aaf47e810c92b2 223 Pfam PF01022 Bacterial regulatory protein, arsR family 15 60 9.4E-15 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFULGI_00014090 154e12ae9980251ff3aaf47e810c92b2 223 SUPERFAMILY SSF46785 3 120 4.2E-23 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00014090 154e12ae9980251ff3aaf47e810c92b2 223 SMART SM00418 7 80 2.3E-15 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFULGI_00014090 154e12ae9980251ff3aaf47e810c92b2 223 Gene3D G3DSA:1.10.10.10 2 97 3.0E-22 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00014090 154e12ae9980251ff3aaf47e810c92b2 223 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 175 215 3.6E-7 T 01-11-2018 IPR002831 Transcription regulator TrmB, N-terminal AFULGI_00014090 154e12ae9980251ff3aaf47e810c92b2 223 Gene3D G3DSA:1.10.10.10 166 223 7.8E-7 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00014090 154e12ae9980251ff3aaf47e810c92b2 223 SUPERFAMILY SSF46785 156 222 7.86E-7 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00011700 e9d7f458d5d1afcd5bd99e730ea20584 413 SUPERFAMILY SSF56801 44 352 2.49E-44 T 01-11-2018 AFULGI_00011700 e9d7f458d5d1afcd5bd99e730ea20584 413 Gene3D G3DSA:3.40.50.12780 6 327 4.0E-116 T 01-11-2018 AFULGI_00011700 e9d7f458d5d1afcd5bd99e730ea20584 413 Gene3D G3DSA:3.30.300.30 328 412 1.3E-14 T 01-11-2018 AFULGI_00011700 e9d7f458d5d1afcd5bd99e730ea20584 413 Pfam PF00501 AMP-binding enzyme 15 286 8.0E-13 T 01-11-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFULGI_00011700 e9d7f458d5d1afcd5bd99e730ea20584 413 Pfam PF14535 AMP-binding enzyme C-terminal domain 336 411 3.3E-7 T 01-11-2018 IPR028154 AMP-dependent ligase, C-terminal AFULGI_00021320 210f3e254583f460fd4a98a51b9e50bf 266 Pfam PF09704 CRISPR-associated protein (Cas_Cas5) 10 194 5.8E-5 T 01-11-2018 IPR021124 CRISPR-associated protein, Cas5 GO:0043571 AFULGI_00021320 210f3e254583f460fd4a98a51b9e50bf 266 Gene3D G3DSA:3.30.70.3120 1 265 7.9E-131 T 01-11-2018 AFULGI_00021320 210f3e254583f460fd4a98a51b9e50bf 266 TIGRFAM TIGR01874 cas_cas5a: CRISPR-associated protein Cas5, subtype I-A/APERN 21 182 2.9E-10 T 01-11-2018 IPR010153 CRISPR-associated protein, Cas5a type AFULGI_00013140 f723c042cec167df5acbd108fec47932 391 ProSitePatterns PS00227 Tubulin subunits alpha, beta, and gamma signature. 108 114 - T 01-11-2018 IPR017975 Tubulin, conserved site GO:0005525|GO:0005874|GO:0007017 Reactome: R-HSA-380320 AFULGI_00013140 f723c042cec167df5acbd108fec47932 391 Gene3D G3DSA:3.40.50.1440 1 229 9.5E-79 T 01-11-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 AFULGI_00013140 f723c042cec167df5acbd108fec47932 391 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 4 172 3.2E-27 T 01-11-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 AFULGI_00013140 f723c042cec167df5acbd108fec47932 391 Hamap MF_01946 Tubulin-like protein CetZ [cetZ]. 1 390 37.265 T 01-11-2018 IPR032907 Tubulin-like protein CetZ GO:0008360 AFULGI_00013140 f723c042cec167df5acbd108fec47932 391 SMART SM00864 2 201 1.3E-21 T 01-11-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 AFULGI_00013140 f723c042cec167df5acbd108fec47932 391 Gene3D G3DSA:3.30.1330.20 230 366 1.8E-41 T 01-11-2018 IPR037103 Tubulin/FtsZ, C-terminal domain superfamily Reactome: R-HSA-380320 AFULGI_00013140 f723c042cec167df5acbd108fec47932 391 SUPERFAMILY SSF52490 2 197 3.66E-41 T 01-11-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 AFULGI_00014680 4b4b9f16d9ae1f5701af5c061c685721 306 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 5 300 7.3E-90 T 01-11-2018 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 AFULGI_00014680 4b4b9f16d9ae1f5701af5c061c685721 306 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 97 299 2.7E-11 T 01-11-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFULGI_00014680 4b4b9f16d9ae1f5701af5c061c685721 306 SUPERFAMILY SSF161098 18 291 1.96E-29 T 01-11-2018 IPR035906 MetI-like superfamily AFULGI_00014680 4b4b9f16d9ae1f5701af5c061c685721 306 Gene3D G3DSA:1.10.3720.10 60 304 8.7E-30 T 01-11-2018 IPR035906 MetI-like superfamily AFULGI_00023570 78f90414e6959b5192102b3f63e5f250 258 Pfam PF01798 snoRNA binding domain, fibrillarin 100 253 1.7E-38 T 01-11-2018 IPR002687 Nop domain AFULGI_00023570 78f90414e6959b5192102b3f63e5f250 258 Gene3D G3DSA:3.30.2150.10 1 71 9.4E-45 T 01-11-2018 AFULGI_00023570 78f90414e6959b5192102b3f63e5f250 258 Gene3D G3DSA:1.10.246.90 139 258 1.1E-43 T 01-11-2018 AFULGI_00023570 78f90414e6959b5192102b3f63e5f250 258 Gene3D G3DSA:1.10.287.660 72 138 1.5E-37 T 01-11-2018 IPR029012 Helix hairpin bin domain superfamily AFULGI_00023570 78f90414e6959b5192102b3f63e5f250 258 SUPERFAMILY SSF89124 2 254 5.89E-60 T 01-11-2018 IPR036070 Nop domain superfamily AFULGI_00024770 de84beb15fe20b2e75591312ebcaded0 508 SUPERFAMILY SSF82171 99 494 9.81E-10 T 01-11-2018 AFULGI_00001550 abfda00907d05aef5be3bb683a2d0d95 180 SUPERFAMILY SSF54862 1 174 9.21E-56 T 01-11-2018 AFULGI_00001550 abfda00907d05aef5be3bb683a2d0d95 180 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 89 100 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFULGI_00001550 abfda00907d05aef5be3bb683a2d0d95 180 Pfam PF13247 4Fe-4S dicluster domain 50 143 1.2E-24 T 01-11-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFULGI_00001550 abfda00907d05aef5be3bb683a2d0d95 180 Gene3D G3DSA:3.30.70.20 7 174 6.5E-54 T 01-11-2018 AFULGI_00001550 abfda00907d05aef5be3bb683a2d0d95 180 Gene3D G3DSA:3.30.70.20 63 115 6.5E-54 T 01-11-2018 AFULGI_00013320 76a67eb8fa0824c55dd9fc8ace5004d9 137 Pfam PF00293 NUDIX domain 13 124 2.9E-20 T 01-11-2018 IPR000086 NUDIX hydrolase domain GO:0016787 AFULGI_00013320 76a67eb8fa0824c55dd9fc8ace5004d9 137 Gene3D G3DSA:3.90.79.10 1 127 6.4E-41 T 01-11-2018 AFULGI_00013320 76a67eb8fa0824c55dd9fc8ace5004d9 137 SUPERFAMILY SSF55811 4 122 1.0E-32 T 01-11-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 AFULGI_00013320 76a67eb8fa0824c55dd9fc8ace5004d9 137 ProSitePatterns PS00893 Nudix box signature. 37 58 - T 01-11-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 AFULGI_00013320 76a67eb8fa0824c55dd9fc8ace5004d9 137 PRINTS PR00502 NUDIX hydrolase family signature 46 61 7.6E-7 T 01-11-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 AFULGI_00013320 76a67eb8fa0824c55dd9fc8ace5004d9 137 PRINTS PR00502 NUDIX hydrolase family signature 32 46 7.6E-7 T 01-11-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 AFULGI_00014770 174c9bf98a01e098f860e1645cb852cf 344 SUPERFAMILY SSF56042 170 337 5.53E-39 T 01-11-2018 IPR036676 PurM-like, C-terminal domain superfamily AFULGI_00014770 174c9bf98a01e098f860e1645cb852cf 344 Pfam PF00586 AIR synthase related protein, N-terminal domain 49 145 1.1E-12 T 01-11-2018 IPR016188 PurM-like, N-terminal domain AFULGI_00014770 174c9bf98a01e098f860e1645cb852cf 344 Pfam PF02769 AIR synthase related protein, C-terminal domain 175 317 1.7E-28 T 01-11-2018 IPR010918 PurM-like, C-terminal domain AFULGI_00014770 174c9bf98a01e098f860e1645cb852cf 344 Gene3D G3DSA:3.30.1330.10 5 151 2.1E-33 T 01-11-2018 IPR036921 PurM-like, N-terminal domain superfamily AFULGI_00014770 174c9bf98a01e098f860e1645cb852cf 344 PIRSF PIRSF005644 1 344 1.1E-120 T 01-11-2018 IPR011854 Carbamoyl dehydratase HypE AFULGI_00014770 174c9bf98a01e098f860e1645cb852cf 344 TIGRFAM TIGR02124 hypE: hydrogenase expression/formation protein HypE 8 344 1.0E-95 T 01-11-2018 IPR011854 Carbamoyl dehydratase HypE AFULGI_00014770 174c9bf98a01e098f860e1645cb852cf 344 SUPERFAMILY SSF55326 49 147 2.44E-20 T 01-11-2018 IPR036921 PurM-like, N-terminal domain superfamily AFULGI_00014770 174c9bf98a01e098f860e1645cb852cf 344 Gene3D G3DSA:3.90.650.10 169 344 1.0E-49 T 01-11-2018 IPR036676 PurM-like, C-terminal domain superfamily AFULGI_00007510 93050124ade18a461b597ded00898589 414 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 9 120 9.4E-21 T 01-11-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 AFULGI_00007510 93050124ade18a461b597ded00898589 414 SUPERFAMILY SSF56645 5 230 6.15E-61 T 01-11-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 AFULGI_00007510 93050124ade18a461b597ded00898589 414 Gene3D G3DSA:1.10.540.10 1 123 1.4E-24 T 01-11-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 AFULGI_00007510 93050124ade18a461b597ded00898589 414 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 233 382 1.3E-37 T 01-11-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AFULGI_00007510 93050124ade18a461b597ded00898589 414 Gene3D G3DSA:1.20.140.10 237 403 8.5E-49 T 01-11-2018 AFULGI_00007510 93050124ade18a461b597ded00898589 414 Gene3D G3DSA:2.40.110.10 125 236 1.3E-31 T 01-11-2018 AFULGI_00007510 93050124ade18a461b597ded00898589 414 SUPERFAMILY SSF47203 231 387 1.27E-45 T 01-11-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 AFULGI_00007510 93050124ade18a461b597ded00898589 414 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 127 220 9.5E-21 T 01-11-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 AFULGI_00007510 93050124ade18a461b597ded00898589 414 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 127 139 - T 01-11-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 AFULGI_00022410 5d562719418b7ea56a5d40cf6a958269 218 Pfam PF01578 Cytochrome C assembly protein 29 164 3.1E-33 T 01-11-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 AFULGI_00022410 5d562719418b7ea56a5d40cf6a958269 218 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 106 126 3.9E-16 T 01-11-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 AFULGI_00022410 5d562719418b7ea56a5d40cf6a958269 218 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 30 47 3.9E-16 T 01-11-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 AFULGI_00022410 5d562719418b7ea56a5d40cf6a958269 218 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 47 67 3.9E-16 T 01-11-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 AFULGI_00022410 5d562719418b7ea56a5d40cf6a958269 218 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 85 105 3.9E-16 T 01-11-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 AFULGI_00022410 5d562719418b7ea56a5d40cf6a958269 218 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 183 207 3.9E-16 T 01-11-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 AFULGI_00010400 f8c31fd5b96b34cd7cf51171820a5e34 157 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 100 111 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFULGI_00010400 f8c31fd5b96b34cd7cf51171820a5e34 157 Pfam PF13247 4Fe-4S dicluster domain 66 150 4.0E-18 T 01-11-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFULGI_00010400 f8c31fd5b96b34cd7cf51171820a5e34 157 Gene3D G3DSA:3.30.70.20 15 150 4.5E-30 T 01-11-2018 AFULGI_00010400 f8c31fd5b96b34cd7cf51171820a5e34 157 Gene3D G3DSA:3.30.70.20 74 126 4.5E-30 T 01-11-2018 AFULGI_00010400 f8c31fd5b96b34cd7cf51171820a5e34 157 SUPERFAMILY SSF54862 6 151 6.38E-42 T 01-11-2018 AFULGI_00004370 f17372bb770a85b47804b455af1c6221 363 Gene3D G3DSA:2.40.30.70 2 142 1.7E-49 T 01-11-2018 IPR036414 YaeB, N-terminal domain superfamily AFULGI_00004370 f17372bb770a85b47804b455af1c6221 363 Pfam PF02663 FmdE, Molybdenum formylmethanofuran dehydrogenase operon 158 299 8.9E-39 T 01-11-2018 IPR003814 Formylmethanofuran dehydrogenase, subunit E domain AFULGI_00004370 f17372bb770a85b47804b455af1c6221 363 ProSitePatterns PS01318 TsaA-like domain signature. 77 88 - T 01-11-2018 IPR023368 Uncharacterised protein family UPF0066, conserved site AFULGI_00004370 f17372bb770a85b47804b455af1c6221 363 Pfam PF01980 Uncharacterised protein family UPF0066 18 129 3.6E-37 T 01-11-2018 IPR023370 YaeB-like, N-terminal domain AFULGI_00004370 f17372bb770a85b47804b455af1c6221 363 SUPERFAMILY SSF118196 2 144 1.83E-49 T 01-11-2018 IPR036413 YaeB-like superfamily AFULGI_00004370 f17372bb770a85b47804b455af1c6221 363 SUPERFAMILY SSF143555 150 315 1.7E-45 T 01-11-2018 AFULGI_00004370 f17372bb770a85b47804b455af1c6221 363 Gene3D G3DSA:3.30.1330.130 143 309 4.8E-44 T 01-11-2018 AFULGI_00004370 f17372bb770a85b47804b455af1c6221 363 TIGRFAM TIGR00104 tRNA_TsaA: tRNA-Thr(GGU) m(6)t(6)A37 methyltransferase TsaA 1 135 1.9E-61 T 01-11-2018 IPR023370 YaeB-like, N-terminal domain AFULGI_00014790 955e116b27ad5aaea5d4b9f8e59ff097 107 Hamap MF_00213 Hydrogenase maturation factor HypA [hypA]. 1 106 17.152 T 01-11-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 AFULGI_00014790 955e116b27ad5aaea5d4b9f8e59ff097 107 PIRSF PIRSF004761 1 107 6.2E-28 T 01-11-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 AFULGI_00014790 955e116b27ad5aaea5d4b9f8e59ff097 107 ProSitePatterns PS01249 Hydrogenases expression/synthesis hypA family signature. 31 73 - T 01-11-2018 IPR020538 Hydrogenase nickel incorporation protein HypA/HybF, conserved site AFULGI_00014790 955e116b27ad5aaea5d4b9f8e59ff097 107 Gene3D G3DSA:2.20.28.10 66 95 4.3E-24 T 01-11-2018 AFULGI_00014790 955e116b27ad5aaea5d4b9f8e59ff097 107 TIGRFAM TIGR00100 hypA: hydrogenase nickel insertion protein HypA 1 106 1.0E-32 T 01-11-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 AFULGI_00014790 955e116b27ad5aaea5d4b9f8e59ff097 107 Gene3D G3DSA:3.30.2320.50 1 102 4.3E-24 T 01-11-2018 AFULGI_00014790 955e116b27ad5aaea5d4b9f8e59ff097 107 Pfam PF01155 Hydrogenase/urease nickel incorporation, metallochaperone, hypA 1 104 1.1E-23 T 01-11-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 AFULGI_00007840 8fa73216935aea8548d6b5871a0b7647 252 Pfam PF01946 Thi4 family 6 232 2.6E-94 T 01-11-2018 AFULGI_00007840 8fa73216935aea8548d6b5871a0b7647 252 SUPERFAMILY SSF51905 2 249 5.77E-43 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFULGI_00007840 8fa73216935aea8548d6b5871a0b7647 252 Hamap MF_00304 Thiamine thiazole synthase [thi4]. 1 251 42.822 T 01-11-2018 IPR022828 Thiazole biosynthetic enzyme, prokaryotic AFULGI_00007840 8fa73216935aea8548d6b5871a0b7647 252 TIGRFAM TIGR00292 TIGR00292: thiazole biosynthesis enzyme 2 251 2.4E-123 T 01-11-2018 IPR002922 Thiazole biosynthetic enzyme Thi4 family AFULGI_00007840 8fa73216935aea8548d6b5871a0b7647 252 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 25 44 1.5E-6 T 01-11-2018 AFULGI_00007840 8fa73216935aea8548d6b5871a0b7647 252 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 159 177 1.5E-6 T 01-11-2018 AFULGI_00007840 8fa73216935aea8548d6b5871a0b7647 252 Gene3D G3DSA:3.50.50.60 1 252 4.7E-92 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFULGI_00007840 8fa73216935aea8548d6b5871a0b7647 252 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 24 46 1.6E-6 T 01-11-2018 AFULGI_00007840 8fa73216935aea8548d6b5871a0b7647 252 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 162 171 1.6E-6 T 01-11-2018 AFULGI_00017630 d130497c00fc2d3318defbfaea3f07d7 881 Pfam PF00583 Acetyltransferase (GNAT) family 67 152 2.6E-14 T 01-11-2018 IPR000182 GNAT domain AFULGI_00017630 d130497c00fc2d3318defbfaea3f07d7 881 Gene3D G3DSA:3.40.50.261 483 647 8.8E-47 T 01-11-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AFULGI_00017630 d130497c00fc2d3318defbfaea3f07d7 881 SUPERFAMILY SSF52210 486 645 1.11E-33 T 01-11-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AFULGI_00017630 d130497c00fc2d3318defbfaea3f07d7 881 Gene3D G3DSA:3.30.470.20 675 875 5.3E-65 T 01-11-2018 AFULGI_00017630 d130497c00fc2d3318defbfaea3f07d7 881 SUPERFAMILY SSF51735 187 325 1.24E-33 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily AFULGI_00017630 d130497c00fc2d3318defbfaea3f07d7 881 Gene3D G3DSA:3.30.1490.20 693 762 5.3E-65 T 01-11-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 AFULGI_00017630 d130497c00fc2d3318defbfaea3f07d7 881 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 343 480 2.8E-48 T 01-11-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain AFULGI_00017630 d130497c00fc2d3318defbfaea3f07d7 881 SUPERFAMILY SSF56059 679 880 1.24E-35 T 01-11-2018 AFULGI_00017630 d130497c00fc2d3318defbfaea3f07d7 881 SMART SM00881 194 289 5.2E-33 T 01-11-2018 IPR003781 CoA-binding GO:0048037 AFULGI_00017630 d130497c00fc2d3318defbfaea3f07d7 881 Gene3D G3DSA:3.40.50.720 190 318 5.4E-41 T 01-11-2018 AFULGI_00017630 d130497c00fc2d3318defbfaea3f07d7 881 Gene3D G3DSA:3.40.50.261 320 482 2.3E-54 T 01-11-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AFULGI_00017630 d130497c00fc2d3318defbfaea3f07d7 881 TIGRFAM TIGR02717 AcCoA-syn-alpha: acetyl coenzyme A synthetase (ADP forming), alpha domain 191 640 4.4E-181 T 01-11-2018 IPR014089 Acetate-CoA ligase [ADP-forming], alpha domain KEGG: 00010+6.2.1.13|KEGG: 00620+6.2.1.13|KEGG: 00640+6.2.1.13|MetaCyc: PWY-5483|MetaCyc: PWY-5535 AFULGI_00017630 d130497c00fc2d3318defbfaea3f07d7 881 Pfam PF13549 ATP-grasp domain 671 877 2.1E-63 T 01-11-2018 AFULGI_00017630 d130497c00fc2d3318defbfaea3f07d7 881 Gene3D G3DSA:3.40.630.30 12 189 6.3E-32 T 01-11-2018 AFULGI_00017630 d130497c00fc2d3318defbfaea3f07d7 881 Pfam PF13380 CoA binding domain 199 324 3.0E-19 T 01-11-2018 IPR003781 CoA-binding GO:0048037 AFULGI_00017630 d130497c00fc2d3318defbfaea3f07d7 881 SUPERFAMILY SSF55729 20 155 2.44E-23 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase AFULGI_00017630 d130497c00fc2d3318defbfaea3f07d7 881 SUPERFAMILY SSF52210 318 487 1.83E-40 T 01-11-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AFULGI_00017900 5c6e064133237363ca73a278fc9fe876 82 SUPERFAMILY SSF52833 1 73 1.86E-17 T 01-11-2018 IPR036249 Thioredoxin-like superfamily AFULGI_00017900 5c6e064133237363ca73a278fc9fe876 82 Pfam PF00462 Glutaredoxin 4 68 7.6E-15 T 01-11-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 AFULGI_00017900 5c6e064133237363ca73a278fc9fe876 82 ProSitePatterns PS00195 Glutaredoxin active site. 6 22 - T 01-11-2018 IPR011767 Glutaredoxin active site GO:0009055|GO:0045454 Reactome: R-HSA-499943 AFULGI_00017900 5c6e064133237363ca73a278fc9fe876 82 Gene3D G3DSA:3.40.30.10 1 82 4.2E-26 T 01-11-2018 AFULGI_00012190 04923c5f6e76d877bfd89139e245b53b 650 Gene3D G3DSA:1.10.1040.10 295 381 2.1E-24 T 01-11-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AFULGI_00012190 04923c5f6e76d877bfd89139e245b53b 650 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2 180 3.0E-64 T 01-11-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 AFULGI_00012190 04923c5f6e76d877bfd89139e245b53b 650 Gene3D G3DSA:1.10.1040.10 185 294 6.3E-29 T 01-11-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AFULGI_00012190 04923c5f6e76d877bfd89139e245b53b 650 Gene3D G3DSA:1.10.12.10 593 650 6.7E-13 T 01-11-2018 IPR014748 Enoyl-CoA hydratase, C-terminal AFULGI_00012190 04923c5f6e76d877bfd89139e245b53b 650 Pfam PF00378 Enoyl-CoA hydratase/isomerase 403 649 9.7E-51 T 01-11-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 AFULGI_00012190 04923c5f6e76d877bfd89139e245b53b 650 Gene3D G3DSA:3.90.226.10 382 590 1.7E-53 T 01-11-2018 AFULGI_00012190 04923c5f6e76d877bfd89139e245b53b 650 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 183 276 1.2E-26 T 01-11-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 AFULGI_00012190 04923c5f6e76d877bfd89139e245b53b 650 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 298 388 1.0E-19 T 01-11-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 AFULGI_00012190 04923c5f6e76d877bfd89139e245b53b 650 SUPERFAMILY SSF52096 388 650 4.98E-70 T 01-11-2018 IPR029045 ClpP/crotonase-like domain superfamily AFULGI_00012190 04923c5f6e76d877bfd89139e245b53b 650 Gene3D G3DSA:3.40.50.720 1 184 4.5E-67 T 01-11-2018 AFULGI_00012190 04923c5f6e76d877bfd89139e245b53b 650 SUPERFAMILY SSF51735 2 178 2.69E-55 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily AFULGI_00012190 04923c5f6e76d877bfd89139e245b53b 650 SUPERFAMILY SSF48179 298 390 5.87E-22 T 01-11-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AFULGI_00012190 04923c5f6e76d877bfd89139e245b53b 650 SUPERFAMILY SSF48179 182 278 1.19E-26 T 01-11-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AFULGI_00019140 cc60e348a1ea3da3523bfcecf89fff29 322 PIRSF PIRSF001439 1 320 8.5E-91 T 01-11-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 AFULGI_00019140 cc60e348a1ea3da3523bfcecf89fff29 322 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 2 311 3.0E-135 T 01-11-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 AFULGI_00019140 cc60e348a1ea3da3523bfcecf89fff29 322 Gene3D G3DSA:3.40.50.720 122 292 3.5E-137 T 01-11-2018 AFULGI_00019140 cc60e348a1ea3da3523bfcecf89fff29 322 SUPERFAMILY SSF51735 1 320 1.1E-107 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily AFULGI_00019140 cc60e348a1ea3da3523bfcecf89fff29 322 TIGRFAM TIGR02371 ala_DH_arch: alanine dehydrogenase 2 320 2.8E-181 T 01-11-2018 IPR012742 Alanine dehydrogenase, Archaeoglobus-type GO:0000286|GO:0006522|GO:0051287 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 AFULGI_00019140 cc60e348a1ea3da3523bfcecf89fff29 322 Gene3D G3DSA:3.30.1780.10 6 314 3.5E-137 T 01-11-2018 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 AFULGI_00019140 cc60e348a1ea3da3523bfcecf89fff29 322 Hamap MF_00935 Alanine dehydrogenase [ala]. 3 318 50.372 T 01-11-2018 IPR028609 Alanine dehydrogenase, archaeal-type GO:0000286|GO:0006522|GO:0051287 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 AFULGI_00017160 4c6cb20cb7af46a218aba68bff4ca739 224 Pfam PF07603 Protein of unknown function (DUF1566) 122 187 3.1E-20 T 01-11-2018 IPR011460 Protein of unknown function DUF1566 AFULGI_00025790 67c73cfaff6c9ecd14d5b119e375361b 613 Gene3D G3DSA:1.10.599.10 251 612 4.2E-144 T 01-11-2018 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 AFULGI_00025790 67c73cfaff6c9ecd14d5b119e375361b 613 Gene3D G3DSA:1.10.569.10 253 441 4.2E-144 T 01-11-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 AFULGI_00025790 67c73cfaff6c9ecd14d5b119e375361b 613 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 7 216 4.5E-79 T 01-11-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 AFULGI_00025790 67c73cfaff6c9ecd14d5b119e375361b 613 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 232 612 1.2E-146 T 01-11-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 AFULGI_00025790 67c73cfaff6c9ecd14d5b119e375361b 613 SUPERFAMILY SSF56228 3 221 5.62E-69 T 01-11-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily AFULGI_00025790 67c73cfaff6c9ecd14d5b119e375361b 613 SMART SM00790 5 218 9.4E-123 T 01-11-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 AFULGI_00025790 67c73cfaff6c9ecd14d5b119e375361b 613 Gene3D G3DSA:3.60.9.10 2 222 1.1E-81 T 01-11-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily AFULGI_00025790 67c73cfaff6c9ecd14d5b119e375361b 613 SUPERFAMILY SSF48310 222 612 5.49E-145 T 01-11-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 AFULGI_00008490 4f53b18a5e09c7805c1d9b27601a8393 595 Gene3D G3DSA:2.40.30.10 467 555 3.7E-31 T 01-11-2018 AFULGI_00008490 4f53b18a5e09c7805c1d9b27601a8393 595 Pfam PF03144 Elongation factor Tu domain 2 251 326 1.5E-9 T 01-11-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 AFULGI_00008490 4f53b18a5e09c7805c1d9b27601a8393 595 SUPERFAMILY SSF52156 337 453 2.62E-29 T 01-11-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily AFULGI_00008490 4f53b18a5e09c7805c1d9b27601a8393 595 Gene3D G3DSA:2.40.30.10 236 352 9.4E-40 T 01-11-2018 AFULGI_00008490 4f53b18a5e09c7805c1d9b27601a8393 595 PRINTS PR00315 GTP-binding elongation factor signature 130 139 2.1E-10 T 01-11-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFULGI_00008490 4f53b18a5e09c7805c1d9b27601a8393 595 PRINTS PR00315 GTP-binding elongation factor signature 15 28 2.1E-10 T 01-11-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFULGI_00008490 4f53b18a5e09c7805c1d9b27601a8393 595 PRINTS PR00315 GTP-binding elongation factor signature 94 105 2.1E-10 T 01-11-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFULGI_00008490 4f53b18a5e09c7805c1d9b27601a8393 595 PRINTS PR00315 GTP-binding elongation factor signature 78 88 2.1E-10 T 01-11-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFULGI_00008490 4f53b18a5e09c7805c1d9b27601a8393 595 SUPERFAMILY SSF52540 11 295 6.33E-53 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00008490 4f53b18a5e09c7805c1d9b27601a8393 595 Pfam PF00009 Elongation factor Tu GTP binding domain 14 220 9.7E-35 T 01-11-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFULGI_00008490 4f53b18a5e09c7805c1d9b27601a8393 595 Gene3D G3DSA:3.40.50.300 10 230 1.1E-64 T 01-11-2018 AFULGI_00008490 4f53b18a5e09c7805c1d9b27601a8393 595 TIGRFAM TIGR00491 aIF-2: translation initiation factor aIF-2 11 595 4.2E-292 T 01-11-2018 IPR004544 Translation initiation factor aIF-2, archaea GO:0003743|GO:0005525|GO:0005622|GO:0006413 AFULGI_00008490 4f53b18a5e09c7805c1d9b27601a8393 595 Pfam PF11987 Translation-initiation factor 2 346 446 1.1E-21 T 01-11-2018 IPR023115 Translation initiation factor IF- 2, domain 3 AFULGI_00008490 4f53b18a5e09c7805c1d9b27601a8393 595 Pfam PF14578 Elongation factor Tu domain 4 467 552 5.5E-28 T 01-11-2018 IPR029459 Elongation factor Tu-type domain AFULGI_00008490 4f53b18a5e09c7805c1d9b27601a8393 595 SUPERFAMILY SSF50447 466 591 3.93E-26 T 01-11-2018 IPR009000 Translation protein, beta-barrel domain superfamily AFULGI_00008490 4f53b18a5e09c7805c1d9b27601a8393 595 Hamap MF_00100_A Translation initiation factor IF-2 [infB]. 9 595 43.319 T 01-11-2018 IPR004544 Translation initiation factor aIF-2, archaea GO:0003743|GO:0005525|GO:0005622|GO:0006413 AFULGI_00008490 4f53b18a5e09c7805c1d9b27601a8393 595 Gene3D G3DSA:3.40.50.10050 353 458 1.1E-31 T 01-11-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily AFULGI_00008490 4f53b18a5e09c7805c1d9b27601a8393 595 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 14 153 1.7E-19 T 01-11-2018 IPR005225 Small GTP-binding protein domain GO:0005525 AFULGI_00001850 b5246b956adf9dd7a1ee500522e02fe3 601 ProSitePatterns PS00455 Putative AMP-binding domain signature. 169 180 - T 01-11-2018 IPR020845 AMP-binding, conserved site AFULGI_00001850 b5246b956adf9dd7a1ee500522e02fe3 601 Pfam PF00501 AMP-binding enzyme 23 452 6.0E-93 T 01-11-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFULGI_00001850 b5246b956adf9dd7a1ee500522e02fe3 601 Gene3D G3DSA:3.40.50.12780 306 443 1.7E-37 T 01-11-2018 AFULGI_00001850 b5246b956adf9dd7a1ee500522e02fe3 601 SUPERFAMILY SSF56801 16 600 6.67E-117 T 01-11-2018 AFULGI_00001850 b5246b956adf9dd7a1ee500522e02fe3 601 Gene3D G3DSA:3.40.50.12780 3 290 1.1E-51 T 01-11-2018 AFULGI_00003360 41eb3e4e5c38cc1dec9621137ec5a9c0 67 Pfam PF00808 Histone-like transcription factor (CBF/NF-Y) and archaeal histone 2 64 6.0E-21 T 01-11-2018 IPR003958 Transcription factor CBF/NF-Y/archaeal histone domain AFULGI_00003360 41eb3e4e5c38cc1dec9621137ec5a9c0 67 SUPERFAMILY SSF47113 2 67 1.15E-20 T 01-11-2018 IPR009072 Histone-fold GO:0046982 AFULGI_00003360 41eb3e4e5c38cc1dec9621137ec5a9c0 67 Gene3D G3DSA:1.10.20.10 1 65 8.3E-22 T 01-11-2018 IPR009072 Histone-fold GO:0046982 AFULGI_00025330 48f339ffa1966dc6f835fc55e1c0b999 63 Gene3D G3DSA:1.20.1260.10 1 57 7.6E-10 T 01-11-2018 IPR012347 Ferritin-like AFULGI_00025330 48f339ffa1966dc6f835fc55e1c0b999 63 Pfam PF02915 Rubrerythrin 5 58 2.3E-7 T 01-11-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 AFULGI_00025330 48f339ffa1966dc6f835fc55e1c0b999 63 SUPERFAMILY SSF47240 1 55 4.92E-10 T 01-11-2018 IPR009078 Ferritin-like superfamily AFULGI_00018930 1f4792b457dcbf3327c5a71eb5640fa7 409 SUPERFAMILY SSF143968 274 405 1.01E-35 T 01-11-2018 AFULGI_00018930 1f4792b457dcbf3327c5a71eb5640fa7 409 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 37 376 5.5E-81 T 01-11-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 AFULGI_00018930 1f4792b457dcbf3327c5a71eb5640fa7 409 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 2 399 8.9E-142 T 01-11-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 AFULGI_00018930 1f4792b457dcbf3327c5a71eb5640fa7 409 SUPERFAMILY SSF50475 38 271 1.57E-52 T 01-11-2018 AFULGI_00018930 1f4792b457dcbf3327c5a71eb5640fa7 409 Gene3D G3DSA:3.40.1670.10 289 398 3.5E-31 T 01-11-2018 AFULGI_00026740 cfa448375c3c8655347f0b72182d6055 160 Gene3D G3DSA:3.30.1460.10 4 149 3.2E-53 T 01-11-2018 AFULGI_00026740 cfa448375c3c8655347f0b72182d6055 160 Pfam PF10061 Uncharacterized conserved protein (DUF2299) 9 144 2.1E-49 T 01-11-2018 IPR018747 Protein of unknown function DUF2299 AFULGI_00026940 c6f8852972518d80b436fce6c471f08c 243 SUPERFAMILY SSF52096 4 232 3.22E-60 T 01-11-2018 IPR029045 ClpP/crotonase-like domain superfamily AFULGI_00026940 c6f8852972518d80b436fce6c471f08c 243 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 229 2.7E-44 T 01-11-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 AFULGI_00026940 c6f8852972518d80b436fce6c471f08c 243 Gene3D G3DSA:3.90.226.10 3 242 3.8E-64 T 01-11-2018 AFULGI_00021340 acaa45feda00458ee63279fe89935e4a 546 TIGRFAM TIGR01587 cas3_core: CRISPR-associated helicase Cas3 40 405 1.1E-120 T 01-11-2018 IPR006474 Helicase Cas3, CRISPR-associated, core AFULGI_00021340 acaa45feda00458ee63279fe89935e4a 546 Pfam PF00271 Helicase conserved C-terminal domain 253 361 4.4E-8 T 01-11-2018 IPR001650 Helicase, C-terminal AFULGI_00021340 acaa45feda00458ee63279fe89935e4a 546 Gene3D G3DSA:3.40.50.300 20 222 1.8E-14 T 01-11-2018 AFULGI_00021340 acaa45feda00458ee63279fe89935e4a 546 Gene3D G3DSA:3.40.50.300 223 410 2.2E-15 T 01-11-2018 AFULGI_00021340 acaa45feda00458ee63279fe89935e4a 546 SMART SM00490 278 361 2.9E-6 T 01-11-2018 IPR001650 Helicase, C-terminal AFULGI_00021340 acaa45feda00458ee63279fe89935e4a 546 SMART SM00487 17 232 2.3E-18 T 01-11-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFULGI_00021340 acaa45feda00458ee63279fe89935e4a 546 Pfam PF00270 DEAD/DEAH box helicase 39 206 4.5E-11 T 01-11-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 AFULGI_00021340 acaa45feda00458ee63279fe89935e4a 546 SUPERFAMILY SSF52540 37 373 2.0E-29 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00026400 b66fd357835e453c6f69af3a1eea9ef6 134 SMART SM00670 1 123 6.8E-20 T 01-11-2018 IPR002716 PIN domain AFULGI_00026400 b66fd357835e453c6f69af3a1eea9ef6 134 Pfam PF01850 PIN domain 4 125 1.4E-17 T 01-11-2018 IPR002716 PIN domain AFULGI_00026400 b66fd357835e453c6f69af3a1eea9ef6 134 Gene3D G3DSA:3.40.50.1010 1 134 2.3E-18 T 01-11-2018 AFULGI_00026400 b66fd357835e453c6f69af3a1eea9ef6 134 SUPERFAMILY SSF88723 1 133 1.63E-22 T 01-11-2018 IPR029060 PIN-like domain superfamily AFULGI_00018660 2d0bd8c5ef178f3a4ec7a7964331b5a5 321 Pfam PF04055 Radical SAM superfamily 9 161 7.2E-12 T 01-11-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFULGI_00018660 2d0bd8c5ef178f3a4ec7a7964331b5a5 321 Gene3D G3DSA:3.20.20.70 3 267 1.5E-31 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFULGI_00018660 2d0bd8c5ef178f3a4ec7a7964331b5a5 321 SUPERFAMILY SSF102114 6 315 1.59E-30 T 01-11-2018 AFULGI_00021070 9755da6e0b5647ce358c9986e1cb7b57 113 SMART SM00418 22 92 0.0071 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFULGI_00021070 9755da6e0b5647ce358c9986e1cb7b57 113 Gene3D G3DSA:1.10.10.10 16 99 6.2E-11 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00021070 9755da6e0b5647ce358c9986e1cb7b57 113 SUPERFAMILY SSF46785 22 100 6.37E-13 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00021070 9755da6e0b5647ce358c9986e1cb7b57 113 Pfam PF01022 Bacterial regulatory protein, arsR family 33 74 7.1E-9 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFULGI_00020310 2762369ed313fb490caf380e692e6065 545 Gene3D G3DSA:3.40.50.970 353 539 1.6E-45 T 01-11-2018 AFULGI_00020310 2762369ed313fb490caf380e692e6065 545 Gene3D G3DSA:3.40.50.970 1 178 5.8E-52 T 01-11-2018 AFULGI_00020310 2762369ed313fb490caf380e692e6065 545 SUPERFAMILY SSF52467 178 348 4.43E-38 T 01-11-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily AFULGI_00020310 2762369ed313fb490caf380e692e6065 545 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 1 169 6.3E-48 T 01-11-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 AFULGI_00020310 2762369ed313fb490caf380e692e6065 545 Gene3D G3DSA:3.40.50.1220 179 351 1.3E-39 T 01-11-2018 AFULGI_00020310 2762369ed313fb490caf380e692e6065 545 SUPERFAMILY SSF52518 1 169 2.99E-44 T 01-11-2018 IPR029061 Thiamin diphosphate-binding fold AFULGI_00020310 2762369ed313fb490caf380e692e6065 545 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 384 526 2.2E-34 T 01-11-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 AFULGI_00020310 2762369ed313fb490caf380e692e6065 545 SUPERFAMILY SSF52518 361 536 2.16E-46 T 01-11-2018 IPR029061 Thiamin diphosphate-binding fold AFULGI_00020310 2762369ed313fb490caf380e692e6065 545 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 186 320 8.3E-30 T 01-11-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 AFULGI_00010040 c9bc9c4f0d83e7fabdf9c23b25207054 283 SUPERFAMILY SSF102114 40 208 3.4E-29 T 01-11-2018 AFULGI_00010040 c9bc9c4f0d83e7fabdf9c23b25207054 283 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 42 53 - T 01-11-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AFULGI_00010040 c9bc9c4f0d83e7fabdf9c23b25207054 283 Gene3D G3DSA:3.20.20.70 27 255 2.9E-32 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFULGI_00010040 c9bc9c4f0d83e7fabdf9c23b25207054 283 SMART SM00729 36 228 0.0011 T 01-11-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 AFULGI_00010040 c9bc9c4f0d83e7fabdf9c23b25207054 283 Pfam PF04055 Radical SAM superfamily 41 188 4.5E-14 T 01-11-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFULGI_00023840 2f979aa0976f029472e17b83063856c4 471 Pfam PF02637 GatB domain 323 470 1.7E-47 T 01-11-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 AFULGI_00023840 2f979aa0976f029472e17b83063856c4 471 Pfam PF02934 GatB/GatE catalytic domain 4 280 1.6E-103 T 01-11-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 AFULGI_00023840 2f979aa0976f029472e17b83063856c4 471 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 3 471 9.5E-205 T 01-11-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 AFULGI_00023840 2f979aa0976f029472e17b83063856c4 471 SUPERFAMILY SSF55931 4 291 1.63E-106 T 01-11-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 AFULGI_00023840 2f979aa0976f029472e17b83063856c4 471 SMART SM00845 323 470 9.9E-53 T 01-11-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 AFULGI_00023840 2f979aa0976f029472e17b83063856c4 471 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 1 471 36.831 T 01-11-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 AFULGI_00023840 2f979aa0976f029472e17b83063856c4 471 Gene3D G3DSA:1.10.10.410 413 471 2.9E-22 T 01-11-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal AFULGI_00023840 2f979aa0976f029472e17b83063856c4 471 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 147 161 - T 01-11-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 AFULGI_00023840 2f979aa0976f029472e17b83063856c4 471 Gene3D G3DSA:1.10.150.380 292 409 9.6E-27 T 01-11-2018 AFULGI_00023840 2f979aa0976f029472e17b83063856c4 471 SUPERFAMILY SSF89095 292 397 3.53E-22 T 01-11-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 AFULGI_00025340 10417b40545a935ef0af81671f32e4db 124 SUPERFAMILY SSF50891 1 123 2.16E-37 T 01-11-2018 IPR029000 Cyclophilin-like domain superfamily AFULGI_00025340 10417b40545a935ef0af81671f32e4db 124 PIRSF PIRSF006456 1 124 1.7E-70 T 01-11-2018 IPR007256 Protein of unknown function DUF369 AFULGI_00025340 10417b40545a935ef0af81671f32e4db 124 Gene3D G3DSA:2.40.100.20 1 124 2.1E-50 T 01-11-2018 AFULGI_00025340 10417b40545a935ef0af81671f32e4db 124 Pfam PF04126 Cyclophilin-like 1 122 2.2E-52 T 01-11-2018 IPR025658 Cyclophilin TM1367-like domain AFULGI_00023440 a222234d3cd70aea9d4d8faec2df425d 268 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 164 181 6.2E-40 T 01-11-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 AFULGI_00023440 a222234d3cd70aea9d4d8faec2df425d 268 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 35 56 6.2E-40 T 01-11-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 AFULGI_00023440 a222234d3cd70aea9d4d8faec2df425d 268 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 22 29 6.2E-40 T 01-11-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 AFULGI_00023440 a222234d3cd70aea9d4d8faec2df425d 268 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 92 109 6.2E-40 T 01-11-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 AFULGI_00023440 a222234d3cd70aea9d4d8faec2df425d 268 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 122 136 6.2E-40 T 01-11-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 AFULGI_00023440 a222234d3cd70aea9d4d8faec2df425d 268 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 66 74 6.2E-40 T 01-11-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 AFULGI_00023440 a222234d3cd70aea9d4d8faec2df425d 268 Pfam PF02110 Hydroxyethylthiazole kinase family 14 256 6.2E-98 T 01-11-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 AFULGI_00023440 a222234d3cd70aea9d4d8faec2df425d 268 Gene3D G3DSA:3.40.1190.20 2 266 2.2E-88 T 01-11-2018 IPR029056 Ribokinase-like AFULGI_00023440 a222234d3cd70aea9d4d8faec2df425d 268 SUPERFAMILY SSF53613 12 264 4.37E-57 T 01-11-2018 IPR029056 Ribokinase-like AFULGI_00023440 a222234d3cd70aea9d4d8faec2df425d 268 TIGRFAM TIGR00694 thiM: hydroxyethylthiazole kinase 14 258 2.0E-101 T 01-11-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 AFULGI_00023440 a222234d3cd70aea9d4d8faec2df425d 268 Hamap MF_00228 Hydroxyethylthiazole kinase [thiM]. 16 259 30.124 T 01-11-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 AFULGI_00023440 a222234d3cd70aea9d4d8faec2df425d 268 PIRSF PIRSF000513 2 267 2.1E-100 T 01-11-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 AFULGI_00012300 6dfcb592041ec2d84009cedeaa2203b0 75 Hamap MF_00192 DNA-directed RNA polymerase subunit K [rpoK]. 9 63 21.208 T 01-11-2018 IPR006111 Archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 AFULGI_00012300 6dfcb592041ec2d84009cedeaa2203b0 75 SMART SM01409 5 57 3.2E-5 T 01-11-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 AFULGI_00012300 6dfcb592041ec2d84009cedeaa2203b0 75 Pfam PF01192 RNA polymerase Rpb6 12 57 7.7E-13 T 01-11-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 AFULGI_00012300 6dfcb592041ec2d84009cedeaa2203b0 75 SUPERFAMILY SSF63562 10 62 1.14E-21 T 01-11-2018 IPR036161 RPB6/omega subunit-like superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 AFULGI_00012300 6dfcb592041ec2d84009cedeaa2203b0 75 Gene3D G3DSA:3.90.940.50 9 62 2.6E-26 T 01-11-2018 AFULGI_00012300 6dfcb592041ec2d84009cedeaa2203b0 75 ProSitePatterns PS01111 RNA polymerases K / 14 to 18 Kd subunits signature. 12 26 - T 01-11-2018 IPR020708 DNA-directed RNA polymerase, 14-18kDa subunit, conserved site GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 AFULGI_00012300 6dfcb592041ec2d84009cedeaa2203b0 75 PIRSF PIRSF000778 4 68 4.3E-26 T 01-11-2018 IPR006111 Archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 AFULGI_00021170 a11c408f4faf3f9feb19bca300b65152 155 Pfam PF09701 CRISPR-associated protein (Cas_Cmr5) 6 150 1.9E-35 T 01-11-2018 IPR010160 CRISPR-associated protein, Cmr5 AFULGI_00021170 a11c408f4faf3f9feb19bca300b65152 155 Gene3D G3DSA:1.10.520.30 1 155 3.7E-57 T 01-11-2018 IPR023101 AF1862-like domain superfamily AFULGI_00021170 a11c408f4faf3f9feb19bca300b65152 155 SUPERFAMILY SSF158568 4 152 9.55E-43 T 01-11-2018 IPR023101 AF1862-like domain superfamily AFULGI_00021170 a11c408f4faf3f9feb19bca300b65152 155 TIGRFAM TIGR01881 cas_Cmr5: CRISPR type III-B/RAMP module-associated protein Cmr5 4 154 4.1E-52 T 01-11-2018 IPR010160 CRISPR-associated protein, Cmr5 AFULGI_00022530 2436027bd7b8429c8cad4841b2e429ba 175 SMART SM01118 1 167 4.8E-25 T 01-11-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 AFULGI_00022530 2436027bd7b8429c8cad4841b2e429ba 175 ProDom PD009560 CYCLASE ADENYLATE CYCLASE ADENYLYL CYAB LYASE CLASS CYAB-TYPE THERMOPHILIC MJ0240 2 142 2.0E-74 T 01-11-2018 AFULGI_00022530 2436027bd7b8429c8cad4841b2e429ba 175 Pfam PF01928 CYTH domain 2 161 5.6E-34 T 01-11-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 AFULGI_00022530 2436027bd7b8429c8cad4841b2e429ba 175 Gene3D G3DSA:2.40.320.10 1 173 1.4E-45 T 01-11-2018 AFULGI_00022530 2436027bd7b8429c8cad4841b2e429ba 175 SUPERFAMILY SSF55154 1 165 1.19E-37 T 01-11-2018 IPR033469 CYTH-like domain superfamily Reactome: R-HSA-196819 AFULGI_00022530 2436027bd7b8429c8cad4841b2e429ba 175 TIGRFAM TIGR00318 cyaB: putative adenylyl cyclase CyaB 1 166 1.1E-70 T 01-11-2018 IPR008173 Adenylyl cyclase CyaB KEGG: 00230+4.6.1.1 AFULGI_00008130 1ac034abca88039b6b14affc6f2f655d 291 Gene3D G3DSA:3.90.650.10 138 291 3.0E-29 T 01-11-2018 IPR036676 PurM-like, C-terminal domain superfamily AFULGI_00008130 1ac034abca88039b6b14affc6f2f655d 291 Hamap MF_02128 Thiamine-monophosphate kinase [thiL]. 1 291 24.799 T 01-11-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 AFULGI_00008130 1ac034abca88039b6b14affc6f2f655d 291 TIGRFAM TIGR01379 thiL: thiamine-phosphate kinase 2 291 1.5E-85 T 01-11-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 AFULGI_00008130 1ac034abca88039b6b14affc6f2f655d 291 Pfam PF00586 AIR synthase related protein, N-terminal domain 27 132 3.3E-20 T 01-11-2018 IPR016188 PurM-like, N-terminal domain AFULGI_00008130 1ac034abca88039b6b14affc6f2f655d 291 Gene3D G3DSA:3.30.1330.10 1 137 2.7E-31 T 01-11-2018 IPR036921 PurM-like, N-terminal domain superfamily AFULGI_00008130 1ac034abca88039b6b14affc6f2f655d 291 SUPERFAMILY SSF55326 3 133 3.29E-29 T 01-11-2018 IPR036921 PurM-like, N-terminal domain superfamily AFULGI_00008130 1ac034abca88039b6b14affc6f2f655d 291 SUPERFAMILY SSF56042 136 277 1.19E-18 T 01-11-2018 IPR036676 PurM-like, C-terminal domain superfamily AFULGI_00008130 1ac034abca88039b6b14affc6f2f655d 291 PIRSF PIRSF005303 1 291 2.0E-76 T 01-11-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 AFULGI_00017030 840586c4d88753fef2fcd2a3ce56e9bd 326 TIGRFAM TIGR02236 recomb_radA: DNA repair and recombination protein RadA 10 322 1.5E-157 T 01-11-2018 IPR011938 DNA recombination/repair protein RadA GO:0003684|GO:0005524|GO:0006281|GO:0006310|GO:0008094 AFULGI_00017030 840586c4d88753fef2fcd2a3ce56e9bd 326 Pfam PF14520 Helix-hairpin-helix domain 10 63 1.8E-13 T 01-11-2018 AFULGI_00017030 840586c4d88753fef2fcd2a3ce56e9bd 326 SUPERFAMILY SSF52540 83 322 2.6E-55 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00017030 840586c4d88753fef2fcd2a3ce56e9bd 326 Hamap MF_00348 DNA repair and recombination protein RadA [radA]. 8 322 77.761 T 01-11-2018 IPR011938 DNA recombination/repair protein RadA GO:0003684|GO:0005524|GO:0006281|GO:0006310|GO:0008094 AFULGI_00017030 840586c4d88753fef2fcd2a3ce56e9bd 326 PIRSF PIRSF005856 1 326 8.1E-130 T 01-11-2018 IPR016467 DNA recombination and repair protein, RecA-like Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579 AFULGI_00017030 840586c4d88753fef2fcd2a3ce56e9bd 326 Gene3D G3DSA:1.10.150.20 9 71 3.4E-23 T 01-11-2018 AFULGI_00017030 840586c4d88753fef2fcd2a3ce56e9bd 326 SMART SM00382 103 292 2.7E-7 T 01-11-2018 IPR003593 AAA+ ATPase domain AFULGI_00017030 840586c4d88753fef2fcd2a3ce56e9bd 326 Pfam PF08423 Rad51 70 322 6.4E-91 T 01-11-2018 IPR013632 DNA recombination and repair protein Rad51-like, C-terminal Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579 AFULGI_00017030 840586c4d88753fef2fcd2a3ce56e9bd 326 SUPERFAMILY SSF47794 8 66 1.88E-13 T 01-11-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 AFULGI_00017030 840586c4d88753fef2fcd2a3ce56e9bd 326 Gene3D G3DSA:3.40.50.300 72 325 2.8E-78 T 01-11-2018 AFULGI_00009090 cb84eb71250cb28ab433926079ee46d8 248 Gene3D G3DSA:3.40.50.300 1 244 2.5E-66 T 01-11-2018 AFULGI_00009090 cb84eb71250cb28ab433926079ee46d8 248 Pfam PF00005 ABC transporter 17 173 2.0E-29 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFULGI_00009090 cb84eb71250cb28ab433926079ee46d8 248 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 221 243 6.5E-10 T 01-11-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal AFULGI_00009090 cb84eb71250cb28ab433926079ee46d8 248 SUPERFAMILY SSF52540 2 244 4.77E-64 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00009090 cb84eb71250cb28ab433926079ee46d8 248 SMART SM00382 26 236 2.0E-12 T 01-11-2018 IPR003593 AAA+ ATPase domain AFULGI_00000820 97cb4a08bd3d6504c8469eed7b3c70e0 244 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 72 239 1.3E-21 T 01-11-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFULGI_00000820 97cb4a08bd3d6504c8469eed7b3c70e0 244 Gene3D G3DSA:1.10.3720.10 42 242 6.4E-23 T 01-11-2018 IPR035906 MetI-like superfamily AFULGI_00000820 97cb4a08bd3d6504c8469eed7b3c70e0 244 SUPERFAMILY SSF161098 49 229 3.14E-27 T 01-11-2018 IPR035906 MetI-like superfamily AFULGI_00021520 a7abe2b50f3ea3925ba3c13b88855948 194 ProSitePatterns PS00052 Ribosomal protein S7 signature. 60 86 - T 01-11-2018 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00021520 a7abe2b50f3ea3925ba3c13b88855948 194 TIGRFAM TIGR01028 uS7_euk_arch: ribosomal protein uS7 9 194 2.8E-96 T 01-11-2018 IPR005716 Ribosomal protein S5/S7, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00021520 a7abe2b50f3ea3925ba3c13b88855948 194 Pfam PF00177 Ribosomal protein S7p/S5e 50 194 1.9E-41 T 01-11-2018 IPR023798 Ribosomal protein S7 domain AFULGI_00021520 a7abe2b50f3ea3925ba3c13b88855948 194 Hamap MF_00480_A 30S ribosomal protein S7 [rpsG]. 10 194 41.036 T 01-11-2018 IPR026018 Ribosomal protein S7, archaeal AFULGI_00021520 a7abe2b50f3ea3925ba3c13b88855948 194 PIRSF PIRSF002122 2 194 1.7E-47 T 01-11-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 AFULGI_00021520 a7abe2b50f3ea3925ba3c13b88855948 194 SUPERFAMILY SSF47973 12 194 2.62E-63 T 01-11-2018 IPR036823 Ribosomal protein S7 domain superfamily AFULGI_00021520 a7abe2b50f3ea3925ba3c13b88855948 194 Gene3D G3DSA:1.10.455.10 2 194 1.1E-81 T 01-11-2018 IPR036823 Ribosomal protein S7 domain superfamily AFULGI_00010180 b4079d407bc224af9a718ed08664981a 209 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 3 202 2.3E-38 T 01-11-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AFULGI_00010180 b4079d407bc224af9a718ed08664981a 209 SUPERFAMILY SSF51366 2 205 7.85E-53 T 01-11-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 AFULGI_00010180 b4079d407bc224af9a718ed08664981a 209 Gene3D G3DSA:3.20.20.70 1 209 8.2E-66 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFULGI_00010180 b4079d407bc224af9a718ed08664981a 209 TIGRFAM TIGR01740 pyrF: orotidine 5'-phosphate decarboxylase 4 204 1.0E-59 T 01-11-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AFULGI_00010180 b4079d407bc224af9a718ed08664981a 209 Hamap MF_01200_A Orotidine 5'-phosphate decarboxylase [pyrF]. 4 209 37.1 T 01-11-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AFULGI_00010180 b4079d407bc224af9a718ed08664981a 209 SMART SM00934 3 203 3.7E-53 T 01-11-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AFULGI_00017400 ea65465c83e062cffcc43a401e9b7d5c 174 Hamap MF_00243 Nicotinamide-nucleotide adenylyltransferase. 1 174 73.121 T 01-11-2018 IPR006418 Nicotinamide-nucleotide adenylyltransferase, archaeal type GO:0000309|GO:0005737|GO:0009435 KEGG: 00760+2.7.7.1 AFULGI_00017400 ea65465c83e062cffcc43a401e9b7d5c 174 SUPERFAMILY SSF52374 6 167 1.66E-29 T 01-11-2018 AFULGI_00017400 ea65465c83e062cffcc43a401e9b7d5c 174 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 6 67 3.3E-17 T 01-11-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 AFULGI_00017400 ea65465c83e062cffcc43a401e9b7d5c 174 Pfam PF01467 Cytidylyltransferase-like 9 138 5.5E-16 T 01-11-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 AFULGI_00017400 ea65465c83e062cffcc43a401e9b7d5c 174 Gene3D G3DSA:3.40.50.620 5 174 5.3E-40 T 01-11-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFULGI_00001860 8fe99695c88d75c2667c566aa9469831 355 SUPERFAMILY SSF53901 9 219 6.25E-14 T 01-11-2018 IPR016039 Thiolase-like GO:0003824 AFULGI_00001860 8fe99695c88d75c2667c566aa9469831 355 SUPERFAMILY SSF53901 221 352 1.92E-13 T 01-11-2018 IPR016039 Thiolase-like GO:0003824 AFULGI_00001860 8fe99695c88d75c2667c566aa9469831 355 Gene3D G3DSA:3.40.47.10 2 355 1.7E-62 T 01-11-2018 IPR016039 Thiolase-like GO:0003824 AFULGI_00001860 8fe99695c88d75c2667c566aa9469831 355 PIRSF PIRSF000429 5 354 3.9E-11 T 01-11-2018 IPR002155 Thiolase GO:0016747 AFULGI_00005310 146704a40f63e7770f814f7cf0c95227 316 Pfam PF01546 Peptidase family M20/M25/M40 51 311 4.1E-20 T 01-11-2018 IPR002933 Peptidase M20 GO:0016787 AFULGI_00005310 146704a40f63e7770f814f7cf0c95227 316 Gene3D G3DSA:3.40.630.10 2 306 3.8E-57 T 01-11-2018 AFULGI_00005310 146704a40f63e7770f814f7cf0c95227 316 Pfam PF07687 Peptidase dimerisation domain 138 221 2.1E-17 T 01-11-2018 IPR011650 Peptidase M20, dimerisation domain AFULGI_00005310 146704a40f63e7770f814f7cf0c95227 316 Gene3D G3DSA:3.30.70.360 139 234 3.8E-57 T 01-11-2018 AFULGI_00005310 146704a40f63e7770f814f7cf0c95227 316 SUPERFAMILY SSF55031 143 221 2.62E-13 T 01-11-2018 IPR036264 Bacterial exopeptidase dimerisation domain AFULGI_00005310 146704a40f63e7770f814f7cf0c95227 316 SUPERFAMILY SSF53187 2 311 2.73E-36 T 01-11-2018 AFULGI_00019730 1724b3b7d8d883d6ac0c9e38558f5a55 1143 Hamap MF_00324 DNA polymerase II large subunit [polC]. 1 1143 519.975 T 01-11-2018 IPR004475 DNA polymerase II large subunit DP2 GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFULGI_00019730 1724b3b7d8d883d6ac0c9e38558f5a55 1143 TIGRFAM TIGR00354 polC: DNA polymerase II, large subunit DP2 24 1142 0.0 T 01-11-2018 IPR004475 DNA polymerase II large subunit DP2 GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFULGI_00019730 1724b3b7d8d883d6ac0c9e38558f5a55 1143 PIRSF PIRSF016275 8 1143 0.0 T 01-11-2018 IPR004475 DNA polymerase II large subunit DP2 GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFULGI_00019730 1724b3b7d8d883d6ac0c9e38558f5a55 1143 Pfam PF03833 DNA polymerase II large subunit DP2 28 893 0.0 T 01-11-2018 IPR016033 DNA polymerase II large subunit DP2, N-terminal KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFULGI_00000720 8d4002edd6e15f644211c5df9f0c714c 578 Gene3D G3DSA:1.10.569.10 238 431 5.0E-54 T 01-11-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 AFULGI_00000720 8d4002edd6e15f644211c5df9f0c714c 578 Gene3D G3DSA:3.60.9.10 1 206 2.5E-57 T 01-11-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily AFULGI_00000720 8d4002edd6e15f644211c5df9f0c714c 578 SUPERFAMILY SSF56228 2 205 1.44E-58 T 01-11-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily AFULGI_00000720 8d4002edd6e15f644211c5df9f0c714c 578 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 218 571 2.3E-60 T 01-11-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 AFULGI_00000720 8d4002edd6e15f644211c5df9f0c714c 578 SMART SM00790 1 204 1.5E-94 T 01-11-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 AFULGI_00000720 8d4002edd6e15f644211c5df9f0c714c 578 Gene3D G3DSA:1.10.599.10 237 562 5.0E-54 T 01-11-2018 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 AFULGI_00000720 8d4002edd6e15f644211c5df9f0c714c 578 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 5 202 4.3E-63 T 01-11-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 AFULGI_00000720 8d4002edd6e15f644211c5df9f0c714c 578 SUPERFAMILY SSF48310 208 573 5.62E-92 T 01-11-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 AFULGI_00007390 7b16558d2884d9a7e42b2e954715219b 511 Gene3D G3DSA:3.40.50.300 231 511 1.7E-117 T 01-11-2018 AFULGI_00007390 7b16558d2884d9a7e42b2e954715219b 511 Pfam PF00437 Type II/IV secretion system protein 134 380 2.5E-50 T 01-11-2018 IPR001482 Type II/IV secretion system protein AFULGI_00007390 7b16558d2884d9a7e42b2e954715219b 511 SUPERFAMILY SSF52540 114 492 1.87E-59 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00007390 7b16558d2884d9a7e42b2e954715219b 511 Gene3D G3DSA:3.30.450.380 1 230 4.6E-102 T 01-11-2018 AFULGI_00001870 8f1d7e57434ea76c0e4182174f74ede4 380 SUPERFAMILY SSF53901 3 224 7.77E-35 T 01-11-2018 IPR016039 Thiolase-like GO:0003824 AFULGI_00001870 8f1d7e57434ea76c0e4182174f74ede4 380 PIRSF PIRSF000429 1 371 2.4E-40 T 01-11-2018 IPR002155 Thiolase GO:0016747 AFULGI_00001870 8f1d7e57434ea76c0e4182174f74ede4 380 Gene3D G3DSA:3.40.47.10 1 378 6.8E-106 T 01-11-2018 IPR016039 Thiolase-like GO:0003824 AFULGI_00001870 8f1d7e57434ea76c0e4182174f74ede4 380 SUPERFAMILY SSF53901 228 375 3.0E-20 T 01-11-2018 IPR016039 Thiolase-like GO:0003824 AFULGI_00001870 8f1d7e57434ea76c0e4182174f74ede4 380 Pfam PF00108 Thiolase, N-terminal domain 3 219 6.9E-13 T 01-11-2018 IPR020616 Thiolase, N-terminal GO:0016747 AFULGI_00010160 3d35887e82e31f72aa601c3fdcec179c 253 PIRSF PIRSF004853 1 251 3.5E-105 T 01-11-2018 IPR002855 Phosphopantoate/pantothenate synthetase AFULGI_00010160 3d35887e82e31f72aa601c3fdcec179c 253 ProDom PD016827 ARCHAEA ST0532 APE1937 VNG0250C MM2281 PAE3406 AF0927 UNCHARACTERIZED C3_0043 MJ0209 66 249 1.0E-99 T 01-11-2018 IPR002855 Phosphopantoate/pantothenate synthetase AFULGI_00010160 3d35887e82e31f72aa601c3fdcec179c 253 Pfam PF02006 Phosphopantothenate/pantothenate synthetase 66 238 2.0E-73 T 01-11-2018 IPR002855 Phosphopantoate/pantothenate synthetase AFULGI_00010160 3d35887e82e31f72aa601c3fdcec179c 253 Gene3D G3DSA:3.40.50.12640 1 252 5.6E-108 T 01-11-2018 IPR038138 Phosphopantoate/pantothenate synthetase superfamily AFULGI_00006690 18e2eea27cb722316fe50aee09511c6a 85 SUPERFAMILY SSF81301 3 80 3.27E-17 T 01-11-2018 AFULGI_00006690 18e2eea27cb722316fe50aee09511c6a 85 Pfam PF01909 Nucleotidyltransferase domain 4 63 2.8E-9 T 01-11-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 AFULGI_00006690 18e2eea27cb722316fe50aee09511c6a 85 Gene3D G3DSA:3.30.460.10 1 84 2.1E-19 T 01-11-2018 AFULGI_00015170 09c72b6585f02a81dc6b3dd1178fb640 154 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 41 146 7.2E-46 T 01-11-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 AFULGI_00015170 09c72b6585f02a81dc6b3dd1178fb640 154 Gene3D G3DSA:2.30.130.10 68 153 5.8E-31 T 01-11-2018 IPR036974 PUA domain superfamily GO:0003723 AFULGI_00015170 09c72b6585f02a81dc6b3dd1178fb640 154 Pfam PF01472 PUA domain 72 144 8.9E-21 T 01-11-2018 IPR002478 PUA domain GO:0003723 AFULGI_00015170 09c72b6585f02a81dc6b3dd1178fb640 154 SUPERFAMILY SSF88697 71 150 1.99E-21 T 01-11-2018 IPR015947 PUA-like superfamily AFULGI_00015170 09c72b6585f02a81dc6b3dd1178fb640 154 SMART SM00359 71 145 4.9E-23 T 01-11-2018 IPR002478 PUA domain GO:0003723 AFULGI_00015170 09c72b6585f02a81dc6b3dd1178fb640 154 PIRSF PIRSF005067 1 153 7.1E-44 T 01-11-2018 IPR016437 MCT-1/Tma20 AFULGI_00015170 09c72b6585f02a81dc6b3dd1178fb640 154 TIGRFAM TIGR03684 arCOG00985: arCOG04150 universal archaeal PUA-domain protein 3 150 1.6E-53 T 01-11-2018 IPR022430 Conserved hypothetical protein CHP03684 AFULGI_00026830 0a5ca9fe282f532d6e354dfbf4fb8749 208 Pfam PF02732 ERCC4 domain 4 107 1.9E-13 T 01-11-2018 IPR006166 ERCC4 domain GO:0003677|GO:0004518 Reactome: R-HSA-6783310 AFULGI_00026830 0a5ca9fe282f532d6e354dfbf4fb8749 208 SUPERFAMILY SSF47781 149 208 2.1E-17 T 01-11-2018 IPR010994 RuvA domain 2-like AFULGI_00026830 0a5ca9fe282f532d6e354dfbf4fb8749 208 Gene3D G3DSA:1.10.150.20 141 208 1.6E-21 T 01-11-2018 AFULGI_00026830 0a5ca9fe282f532d6e354dfbf4fb8749 208 Gene3D G3DSA:3.40.50.10130 1 139 1.5E-26 T 01-11-2018 AFULGI_00026830 0a5ca9fe282f532d6e354dfbf4fb8749 208 SMART SM00278 155 174 0.0028 T 01-11-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 AFULGI_00026830 0a5ca9fe282f532d6e354dfbf4fb8749 208 SMART SM00278 187 206 0.076 T 01-11-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 AFULGI_00026830 0a5ca9fe282f532d6e354dfbf4fb8749 208 SUPERFAMILY SSF52980 2 107 2.6E-19 T 01-11-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 AFULGI_00026830 0a5ca9fe282f532d6e354dfbf4fb8749 208 SMART SM00891 1 84 4.7E-17 T 01-11-2018 IPR006166 ERCC4 domain GO:0003677|GO:0004518 Reactome: R-HSA-6783310 AFULGI_00026830 0a5ca9fe282f532d6e354dfbf4fb8749 208 Pfam PF12826 Helix-hairpin-helix motif 159 208 2.4E-13 T 01-11-2018 AFULGI_00010320 5a319421e44f0f583f826d97a0c540f7 261 Hamap MF_00060 5'/3'-nucleotidase SurE [surE]. 1 259 37.096 T 01-11-2018 IPR030048 Survival protein SurE GO:0008252 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 AFULGI_00010320 5a319421e44f0f583f826d97a0c540f7 261 SUPERFAMILY SSF64167 1 258 7.19E-80 T 01-11-2018 AFULGI_00010320 5a319421e44f0f583f826d97a0c540f7 261 TIGRFAM TIGR00087 surE: 5'/3'-nucleotidase SurE 1 242 7.7E-90 T 01-11-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 AFULGI_00010320 5a319421e44f0f583f826d97a0c540f7 261 Pfam PF01975 Survival protein SurE 3 193 3.5E-52 T 01-11-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 AFULGI_00010320 5a319421e44f0f583f826d97a0c540f7 261 Gene3D G3DSA:3.40.1210.10 1 256 1.4E-85 T 01-11-2018 IPR036523 SurE-like phosphatase/nucleotidase superfamily GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 AFULGI_00011450 6d3aad92e7afae27ae38f2a7d62b1d6b 541 Pfam PF00482 Type II secretion system (T2SS), protein F 42 168 1.6E-8 T 01-11-2018 IPR018076 Type II secretion system F domain AFULGI_00011450 6d3aad92e7afae27ae38f2a7d62b1d6b 541 Pfam PF00482 Type II secretion system (T2SS), protein F 301 431 2.3E-9 T 01-11-2018 IPR018076 Type II secretion system F domain AFULGI_00026170 177a672d88a77ca67d11d1cf0dee89dd 199 Gene3D G3DSA:3.20.20.140 7 178 3.1E-30 T 01-11-2018 AFULGI_00026170 177a672d88a77ca67d11d1cf0dee89dd 199 Hamap MF_00756 Ribonuclease P protein component 3 [rnp3]. 6 184 19.155 T 01-11-2018 IPR023539 Ribonuclease P, protein component 3, archaeal GO:0001682|GO:0004526 AFULGI_00026170 177a672d88a77ca67d11d1cf0dee89dd 199 ProDom PD016938 P COMPONENT RIBONUCLEASE RNASE HYDROLASE PROCESSING TRNA SUBUNIT SIMILAR P/RNASE 90 168 1.0E-38 T 01-11-2018 AFULGI_00026170 177a672d88a77ca67d11d1cf0dee89dd 199 SUPERFAMILY SSF89550 16 177 5.1E-22 T 01-11-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 AFULGI_00026170 177a672d88a77ca67d11d1cf0dee89dd 199 Pfam PF01876 RNase P subunit p30 59 168 1.1E-16 T 01-11-2018 IPR002738 RNase P subunit p30 GO:0004540|GO:0008033 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 AFULGI_00011070 d8bd0f6ed32aed8d2260ea79ff4f955a 306 Pfam PF01694 Rhomboid family 147 298 1.3E-36 T 01-11-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 AFULGI_00011070 d8bd0f6ed32aed8d2260ea79ff4f955a 306 Gene3D G3DSA:1.20.1540.10 107 294 6.6E-34 T 01-11-2018 IPR035952 Rhomboid-like superfamily AFULGI_00011070 d8bd0f6ed32aed8d2260ea79ff4f955a 306 SUPERFAMILY SSF118310 28 82 8.11E-15 T 01-11-2018 IPR035896 AN1-like Zinc finger AFULGI_00011070 d8bd0f6ed32aed8d2260ea79ff4f955a 306 Pfam PF01428 AN1-like Zinc finger 42 78 2.8E-13 T 01-11-2018 IPR000058 Zinc finger, AN1-type GO:0008270 AFULGI_00011070 d8bd0f6ed32aed8d2260ea79ff4f955a 306 SMART SM00154 42 79 1.3E-18 T 01-11-2018 IPR000058 Zinc finger, AN1-type GO:0008270 AFULGI_00011070 d8bd0f6ed32aed8d2260ea79ff4f955a 306 Gene3D G3DSA:4.10.1110.10 25 87 1.0E-12 T 01-11-2018 IPR035896 AN1-like Zinc finger AFULGI_00011070 d8bd0f6ed32aed8d2260ea79ff4f955a 306 SUPERFAMILY SSF144091 112 298 4.19E-37 T 01-11-2018 AFULGI_00011960 59dda8d5d54cda9250f6935e8c8a776b 272 TIGRFAM TIGR00722 ttdA_fumA_fumB: hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type 7 270 8.9E-126 T 01-11-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 AFULGI_00011960 59dda8d5d54cda9250f6935e8c8a776b 272 Pfam PF05681 Fumarate hydratase (Fumerase) 8 269 9.0E-100 T 01-11-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 AFULGI_00002840 1e7d6301077e36767021c2acf2a96355 243 Pfam PF00005 ABC transporter 43 174 2.2E-23 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFULGI_00002840 1e7d6301077e36767021c2acf2a96355 243 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFULGI_00002840 1e7d6301077e36767021c2acf2a96355 243 Gene3D G3DSA:3.40.50.300 19 243 2.4E-49 T 01-11-2018 AFULGI_00002840 1e7d6301077e36767021c2acf2a96355 243 SUPERFAMILY SSF52540 29 235 3.04E-48 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00002840 1e7d6301077e36767021c2acf2a96355 243 SMART SM00382 52 241 2.5E-12 T 01-11-2018 IPR003593 AAA+ ATPase domain AFULGI_00015020 a2f6be0a29eb30e074c25ec790a077dc 425 Pfam PF13458 Periplasmic binding protein 37 404 4.7E-35 T 01-11-2018 IPR028081 Leucine-binding protein domain AFULGI_00015020 a2f6be0a29eb30e074c25ec790a077dc 425 Gene3D G3DSA:3.40.50.2300 163 304 9.2E-51 T 01-11-2018 AFULGI_00015020 a2f6be0a29eb30e074c25ec790a077dc 425 SUPERFAMILY SSF53822 37 411 1.59E-54 T 01-11-2018 IPR028082 Periplasmic binding protein-like I AFULGI_00015020 a2f6be0a29eb30e074c25ec790a077dc 425 Gene3D G3DSA:3.40.50.2300 45 367 9.2E-51 T 01-11-2018 AFULGI_00021190 c26a275ee5a7ab30f894c85927755c46 104 TIGRFAM TIGR02579 cas_csx3: CRISPR-associated protein, Csx3 family 11 91 4.3E-43 T 01-11-2018 IPR013409 CRISPR-associated protein Csx3 AFULGI_00021190 c26a275ee5a7ab30f894c85927755c46 104 Pfam PF09620 CRISPR-associated protein (Cas_csx3) 15 90 4.3E-33 T 01-11-2018 IPR013409 CRISPR-associated protein Csx3 AFULGI_00012740 7b6f499909c35e788e3330d5460a619d 434 SUPERFAMILY SSF47203 274 419 5.96E-34 T 01-11-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 AFULGI_00012740 7b6f499909c35e788e3330d5460a619d 434 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 11 122 2.7E-14 T 01-11-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 AFULGI_00012740 7b6f499909c35e788e3330d5460a619d 434 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 137 247 8.1E-13 T 01-11-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 AFULGI_00012740 7b6f499909c35e788e3330d5460a619d 434 Gene3D G3DSA:2.40.110.10 136 263 2.2E-24 T 01-11-2018 AFULGI_00012740 7b6f499909c35e788e3330d5460a619d 434 Gene3D G3DSA:1.10.540.10 8 131 5.0E-20 T 01-11-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 AFULGI_00012740 7b6f499909c35e788e3330d5460a619d 434 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 277 413 4.8E-27 T 01-11-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AFULGI_00012740 7b6f499909c35e788e3330d5460a619d 434 Gene3D G3DSA:1.20.140.10 265 428 1.2E-34 T 01-11-2018 AFULGI_00012740 7b6f499909c35e788e3330d5460a619d 434 SUPERFAMILY SSF56645 9 255 7.33E-45 T 01-11-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 AFULGI_00019740 628a206f7bffc8050c4d8d20eeece94a 138 SUPERFAMILY SSF46785 1 60 1.14E-12 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00019740 628a206f7bffc8050c4d8d20eeece94a 138 SMART SM00344 1 106 7.8E-33 T 01-11-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 AFULGI_00019740 628a206f7bffc8050c4d8d20eeece94a 138 Pfam PF01037 Lrp/AsnC ligand binding domain 67 134 1.4E-11 T 01-11-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain AFULGI_00019740 628a206f7bffc8050c4d8d20eeece94a 138 SUPERFAMILY SSF54909 65 138 7.51E-13 T 01-11-2018 IPR011008 Dimeric alpha-beta barrel AFULGI_00019740 628a206f7bffc8050c4d8d20eeece94a 138 Gene3D G3DSA:3.30.70.920 64 138 2.0E-15 T 01-11-2018 AFULGI_00019740 628a206f7bffc8050c4d8d20eeece94a 138 Pfam PF13404 AsnC-type helix-turn-helix domain 2 42 6.8E-12 T 01-11-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFULGI_00019740 628a206f7bffc8050c4d8d20eeece94a 138 Gene3D G3DSA:1.10.10.10 1 52 1.1E-14 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00019740 628a206f7bffc8050c4d8d20eeece94a 138 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 3.8E-7 T 01-11-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFULGI_00019740 628a206f7bffc8050c4d8d20eeece94a 138 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 3.8E-7 T 01-11-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFULGI_00019740 628a206f7bffc8050c4d8d20eeece94a 138 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 3.8E-7 T 01-11-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFULGI_00023430 4d031bec0b4959f15c88ff01e9352664 210 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 8 204 28.899 T 01-11-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 AFULGI_00023430 4d031bec0b4959f15c88ff01e9352664 210 SUPERFAMILY SSF51391 6 206 2.35E-64 T 01-11-2018 IPR036206 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 AFULGI_00023430 4d031bec0b4959f15c88ff01e9352664 210 Gene3D G3DSA:3.20.20.70 1 206 1.0E-68 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFULGI_00023430 4d031bec0b4959f15c88ff01e9352664 210 Pfam PF02581 Thiamine monophosphate synthase 10 186 7.0E-62 T 01-11-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 AFULGI_00023430 4d031bec0b4959f15c88ff01e9352664 210 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 9 199 2.2E-63 T 01-11-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 AFULGI_00017370 c3e9ab105f513d9c23d2a65929fa6729 471 Hamap MF_01904 Phosphoenolpyruvate carboxylase [ppcA]. 1 471 38.424 T 01-11-2018 IPR007566 Phosphoenolpyruvate carboxylase, archaeal-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 AFULGI_00017370 c3e9ab105f513d9c23d2a65929fa6729 471 TIGRFAM TIGR02751 PEPCase_arch: phosphoenolpyruvate carboxylase 2 471 4.1E-193 T 01-11-2018 IPR007566 Phosphoenolpyruvate carboxylase, archaeal-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 AFULGI_00017370 c3e9ab105f513d9c23d2a65929fa6729 471 PIRSF PIRSF006677 1 471 4.6E-191 T 01-11-2018 IPR007566 Phosphoenolpyruvate carboxylase, archaeal-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 AFULGI_00017370 c3e9ab105f513d9c23d2a65929fa6729 471 SUPERFAMILY SSF51621 118 410 3.4E-32 T 01-11-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 AFULGI_00017370 c3e9ab105f513d9c23d2a65929fa6729 471 Pfam PF14010 Phosphoenolpyruvate carboxylase 2 471 5.0E-184 T 01-11-2018 IPR007566 Phosphoenolpyruvate carboxylase, archaeal-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 AFULGI_00020880 a9f02cb076c190834faca75b054d9ed3 189 Gene3D G3DSA:1.20.58.290 124 189 7.0E-31 T 01-11-2018 AFULGI_00020880 a9f02cb076c190834faca75b054d9ed3 189 Gene3D G3DSA:2.30.110.10 1 123 1.1E-36 T 01-11-2018 IPR012349 FMN-binding split barrel GO:0048037 AFULGI_00020880 a9f02cb076c190834faca75b054d9ed3 189 SUPERFAMILY SSF50475 1 188 2.22E-52 T 01-11-2018 AFULGI_00020880 a9f02cb076c190834faca75b054d9ed3 189 Pfam PF04289 Protein of unknown function (DUF447) 13 186 4.1E-48 T 01-11-2018 IPR007386 Protein of unknown function DUF447 AFULGI_00000440 ec59a97424e802e89e3b6f185479fbd5 399 Gene3D G3DSA:3.30.300.340 14 280 2.6E-160 T 01-11-2018 AFULGI_00000440 ec59a97424e802e89e3b6f185479fbd5 399 ProDom PD011777 SYNTHETASE TRANSFERASE METHIONINE ADENOSYLTRANSFERASE S-ADENOSYLMETHIONINE NUCLEOTIDE-BINDING METABOLISM ATP-BINDING MAGNESIUM ONE-CARBON 20 384 0.0 T 01-11-2018 AFULGI_00000440 ec59a97424e802e89e3b6f185479fbd5 399 Hamap MF_00136 S-adenosylmethionine synthase [mat]. 1 399 52.27 T 01-11-2018 IPR002795 S-adenosylmethionine synthetase, archaea GO:0004478|GO:0005524|GO:0006730 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912 AFULGI_00000440 ec59a97424e802e89e3b6f185479fbd5 399 Pfam PF01941 S-adenosylmethionine synthetase (AdoMet synthetase) 3 395 1.0E-178 T 01-11-2018 IPR027790 S-adenosylmethionine synthase KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912 AFULGI_00000440 ec59a97424e802e89e3b6f185479fbd5 399 Gene3D G3DSA:3.30.300.10 26 152 2.6E-160 T 01-11-2018 AFULGI_00000440 ec59a97424e802e89e3b6f185479fbd5 399 Gene3D G3DSA:3.30.300.280 12 392 2.6E-160 T 01-11-2018 AFULGI_00018320 623ee50f57f6c52100ce94cda8df8a89 166 SUPERFAMILY SSF46785 1 76 8.16E-17 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00018320 623ee50f57f6c52100ce94cda8df8a89 166 PIRSF PIRSF019345 1 165 3.3E-46 T 01-11-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 AFULGI_00018320 623ee50f57f6c52100ce94cda8df8a89 166 Gene3D G3DSA:1.10.10.10 75 161 5.7E-19 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00018320 623ee50f57f6c52100ce94cda8df8a89 166 Pfam PF04079 Segregation and condensation complex subunit ScpB 6 151 2.4E-43 T 01-11-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 AFULGI_00018320 623ee50f57f6c52100ce94cda8df8a89 166 SUPERFAMILY SSF46785 79 147 5.89E-18 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00018320 623ee50f57f6c52100ce94cda8df8a89 166 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 2 166 9.4E-64 T 01-11-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 AFULGI_00018320 623ee50f57f6c52100ce94cda8df8a89 166 Gene3D G3DSA:1.10.10.10 1 74 2.8E-17 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00018990 93b76cd19cbcb93a30c583870541e9cd 156 Pfam PF00037 4Fe-4S binding domain 74 93 9.9E-8 T 01-11-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFULGI_00018990 93b76cd19cbcb93a30c583870541e9cd 156 Pfam PF04060 Putative Fe-S cluster 12 44 2.7E-14 T 01-11-2018 IPR007202 4Fe-4S domain GO:0051536 AFULGI_00018990 93b76cd19cbcb93a30c583870541e9cd 156 SUPERFAMILY SSF54862 9 153 5.76E-12 T 01-11-2018 AFULGI_00018990 93b76cd19cbcb93a30c583870541e9cd 156 Gene3D G3DSA:3.30.70.20 73 153 3.5E-9 T 01-11-2018 AFULGI_00018990 93b76cd19cbcb93a30c583870541e9cd 156 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 80 91 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFULGI_00018990 93b76cd19cbcb93a30c583870541e9cd 156 Gene3D G3DSA:1.10.15.40 2 57 2.3E-21 T 01-11-2018 AFULGI_00011320 08d045bdd221110e060b8252fe2149d8 282 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 17 97 5.4E-9 T 01-11-2018 IPR000014 PAS domain AFULGI_00011320 08d045bdd221110e060b8252fe2149d8 282 SMART SM00091 17 80 4.0E-6 T 01-11-2018 IPR000014 PAS domain AFULGI_00011320 08d045bdd221110e060b8252fe2149d8 282 SUPERFAMILY SSF55785 6 109 1.08E-11 T 01-11-2018 IPR035965 PAS domain superfamily AFULGI_00011320 08d045bdd221110e060b8252fe2149d8 282 Pfam PF08448 PAS fold 23 108 8.3E-9 T 01-11-2018 IPR013656 PAS fold-4 AFULGI_00011320 08d045bdd221110e060b8252fe2149d8 282 Gene3D G3DSA:3.30.450.20 24 129 5.4E-10 T 01-11-2018 AFULGI_00008660 e20d82cebb41f8ba84010d610ec54996 351 Gene3D G3DSA:3.30.460.20 18 159 9.8E-51 T 01-11-2018 AFULGI_00008660 e20d82cebb41f8ba84010d610ec54996 351 Gene3D G3DSA:1.20.58.340 274 351 1.3E-35 T 01-11-2018 AFULGI_00008660 e20d82cebb41f8ba84010d610ec54996 351 TIGRFAM TIGR00383 corA: magnesium and cobalt transport protein CorA 33 351 1.4E-128 T 01-11-2018 IPR004488 Magnesium/cobalt transport protein CorA GO:0006824|GO:0015087|GO:0015095|GO:0015693|GO:0016020 AFULGI_00008660 e20d82cebb41f8ba84010d610ec54996 351 Pfam PF01544 CorA-like Mg2+ transporter protein 65 347 1.8E-74 T 01-11-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 AFULGI_00008660 e20d82cebb41f8ba84010d610ec54996 351 SUPERFAMILY SSF143865 10 285 1.09E-69 T 01-11-2018 AFULGI_00008660 e20d82cebb41f8ba84010d610ec54996 351 Gene3D G3DSA:1.20.58.340 160 263 1.9E-37 T 01-11-2018 AFULGI_00008660 e20d82cebb41f8ba84010d610ec54996 351 SUPERFAMILY SSF144083 286 349 1.26E-23 T 01-11-2018 AFULGI_00006760 e1d3c54f533568d4eb37b39566d89bf6 344 Gene3D G3DSA:3.40.50.150 153 334 1.5E-31 T 01-11-2018 AFULGI_00006760 e1d3c54f533568d4eb37b39566d89bf6 344 Pfam PF05050 Methyltransferase FkbM domain 172 318 2.1E-17 T 01-11-2018 IPR006342 Methyltransferase FkbM AFULGI_00006760 e1d3c54f533568d4eb37b39566d89bf6 344 TIGRFAM TIGR01444 fkbM_fam: methyltransferase, FkbM family 169 307 4.9E-38 T 01-11-2018 IPR006342 Methyltransferase FkbM AFULGI_00006760 e1d3c54f533568d4eb37b39566d89bf6 344 SUPERFAMILY SSF53335 87 331 1.89E-45 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFULGI_00007540 bb04adad7e4da755c95a4eb214e89afd 122 SUPERFAMILY SSF46785 14 112 1.57E-10 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00007540 bb04adad7e4da755c95a4eb214e89afd 122 PIRSF PIRSF037373 1 120 3.9E-49 T 01-11-2018 IPR017185 Uncharacterised conserved protein UCP037373, transcriptional regulator, AF0674 AFULGI_00007540 bb04adad7e4da755c95a4eb214e89afd 122 Gene3D G3DSA:1.10.10.10 7 117 1.9E-13 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00025880 c78d9eb59b231a3e5cd34559166ad258 284 Hamap MF_00217 Mevalonate kinase [mvk]. 1 280 52.254 T 01-11-2018 IPR022937 Mevalonate kinase, archaeal GO:0004496 KEGG: 00900+2.7.1.36|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-922 AFULGI_00025880 c78d9eb59b231a3e5cd34559166ad258 284 Gene3D G3DSA:3.30.70.890 160 281 7.9E-30 T 01-11-2018 IPR036554 GHMP kinase, C-terminal domain superfamily AFULGI_00025880 c78d9eb59b231a3e5cd34559166ad258 284 Gene3D G3DSA:3.30.230.10 1 159 7.8E-52 T 01-11-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AFULGI_00025880 c78d9eb59b231a3e5cd34559166ad258 284 TIGRFAM TIGR00549 mevalon_kin: mevalonate kinase 5 260 1.7E-80 T 01-11-2018 IPR006205 Mevalonate kinase GO:0004496|GO:0005524|GO:0005737|GO:0008299 KEGG: 00900+2.7.1.36|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-2426168 AFULGI_00025880 c78d9eb59b231a3e5cd34559166ad258 284 SUPERFAMILY SSF54211 1 168 4.1E-40 T 01-11-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFULGI_00025880 c78d9eb59b231a3e5cd34559166ad258 284 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 85 96 - T 01-11-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 AFULGI_00025880 c78d9eb59b231a3e5cd34559166ad258 284 Pfam PF08544 GHMP kinases C terminal 203 264 1.5E-13 T 01-11-2018 IPR013750 GHMP kinase, C-terminal domain AFULGI_00025880 c78d9eb59b231a3e5cd34559166ad258 284 Pfam PF00288 GHMP kinases N terminal domain 79 144 5.0E-18 T 01-11-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 AFULGI_00025880 c78d9eb59b231a3e5cd34559166ad258 284 PRINTS PR00959 Mevalonate kinase family signature 5 29 3.9E-26 T 01-11-2018 AFULGI_00025880 c78d9eb59b231a3e5cd34559166ad258 284 PRINTS PR00959 Mevalonate kinase family signature 83 105 3.9E-26 T 01-11-2018 AFULGI_00025880 c78d9eb59b231a3e5cd34559166ad258 284 PRINTS PR00959 Mevalonate kinase family signature 246 263 3.9E-26 T 01-11-2018 AFULGI_00025880 c78d9eb59b231a3e5cd34559166ad258 284 PRINTS PR00959 Mevalonate kinase family signature 126 145 3.9E-26 T 01-11-2018 AFULGI_00025880 c78d9eb59b231a3e5cd34559166ad258 284 SUPERFAMILY SSF55060 161 267 3.5E-24 T 01-11-2018 IPR036554 GHMP kinase, C-terminal domain superfamily AFULGI_00014840 6354690113f7b0120f623b2005088a34 458 ProSitePatterns PS00508 Nickel-dependent hydrogenases large subunit signature 2. 411 420 - T 01-11-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 AFULGI_00014840 6354690113f7b0120f623b2005088a34 458 Pfam PF00374 Nickel-dependent hydrogenase 274 420 4.2E-11 T 01-11-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 AFULGI_00014840 6354690113f7b0120f623b2005088a34 458 Pfam PF00374 Nickel-dependent hydrogenase 38 117 6.5E-14 T 01-11-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 AFULGI_00014840 6354690113f7b0120f623b2005088a34 458 SUPERFAMILY SSF56762 1 420 1.26E-94 T 01-11-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFULGI_00014840 6354690113f7b0120f623b2005088a34 458 Gene3D G3DSA:1.10.645.10 1 420 7.6E-98 T 01-11-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFULGI_00021450 9156be1bbf07b38636a2654d070b46b7 512 Pfam PF04563 RNA polymerase beta subunit 17 403 8.5E-39 T 01-11-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFULGI_00021450 9156be1bbf07b38636a2654d070b46b7 512 Gene3D G3DSA:3.90.1110.10 186 341 2.7E-52 T 01-11-2018 IPR037034 RNA polymerase Rpb2, domain 2 superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFULGI_00021450 9156be1bbf07b38636a2654d070b46b7 512 Gene3D G3DSA:3.90.1100.10 342 506 1.1E-52 T 01-11-2018 AFULGI_00021450 9156be1bbf07b38636a2654d070b46b7 512 Pfam PF04565 RNA polymerase Rpb2, domain 3 424 488 5.5E-27 T 01-11-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFULGI_00021450 9156be1bbf07b38636a2654d070b46b7 512 Pfam PF04561 RNA polymerase Rpb2, domain 2 185 356 3.5E-29 T 01-11-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFULGI_00021450 9156be1bbf07b38636a2654d070b46b7 512 SUPERFAMILY SSF64484 5 510 1.62E-132 T 01-11-2018 AFULGI_00024260 8757bcbfe5226fc7b614f70a44106085 437 Gene3D G3DSA:1.10.1410.30 9 255 4.0E-100 T 01-11-2018 AFULGI_00024260 8757bcbfe5226fc7b614f70a44106085 437 SUPERFAMILY SSF81301 1 141 8.72E-43 T 01-11-2018 AFULGI_00024260 8757bcbfe5226fc7b614f70a44106085 437 Hamap MF_01264 CCA-adding enzyme [cca]. 1 437 157.981 T 01-11-2018 IPR008229 tRNA nucleotidyltransferase, archaea GO:0001680|GO:0003723|GO:0004810 AFULGI_00024260 8757bcbfe5226fc7b614f70a44106085 437 PIRSF PIRSF005335 1 437 8.8E-158 T 01-11-2018 IPR008229 tRNA nucleotidyltransferase, archaea GO:0001680|GO:0003723|GO:0004810 AFULGI_00024260 8757bcbfe5226fc7b614f70a44106085 437 SUPERFAMILY SSF55003 241 434 3.77E-51 T 01-11-2018 IPR011068 Nucleotidyltransferase, class I-like, C-terminal GO:0003723|GO:0016779|GO:0031123 AFULGI_00024260 8757bcbfe5226fc7b614f70a44106085 437 Gene3D G3DSA:3.30.70.1550 340 383 2.3E-58 T 01-11-2018 AFULGI_00024260 8757bcbfe5226fc7b614f70a44106085 437 TIGRFAM TIGR03671 cca_archaeal: CCA-adding enzyme 7 403 1.8E-144 T 01-11-2018 IPR008229 tRNA nucleotidyltransferase, archaea GO:0001680|GO:0003723|GO:0004810 AFULGI_00024260 8757bcbfe5226fc7b614f70a44106085 437 Pfam PF01909 Nucleotidyltransferase domain 27 132 1.7E-18 T 01-11-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 AFULGI_00024260 8757bcbfe5226fc7b614f70a44106085 437 SUPERFAMILY SSF81631 144 256 1.31E-35 T 01-11-2018 AFULGI_00024260 8757bcbfe5226fc7b614f70a44106085 437 Gene3D G3DSA:3.30.460.10 16 143 4.0E-100 T 01-11-2018 AFULGI_00024260 8757bcbfe5226fc7b614f70a44106085 437 Gene3D G3DSA:3.30.70.590 265 420 2.3E-58 T 01-11-2018 AFULGI_00024260 8757bcbfe5226fc7b614f70a44106085 437 Pfam PF09249 tRNA nucleotidyltransferase, second domain 146 254 2.3E-40 T 01-11-2018 IPR015329 tRNA nucleotidyltransferase, substrate binding GO:0004810|GO:0016437 AFULGI_00024610 d78257fa6c866c8847482a51aacd3c74 136 Gene3D G3DSA:3.40.50.1010 2 136 4.0E-21 T 01-11-2018 AFULGI_00024610 d78257fa6c866c8847482a51aacd3c74 136 SUPERFAMILY SSF88723 1 133 1.04E-22 T 01-11-2018 IPR029060 PIN-like domain superfamily AFULGI_00024610 d78257fa6c866c8847482a51aacd3c74 136 Pfam PF01850 PIN domain 3 132 3.1E-29 T 01-11-2018 IPR002716 PIN domain AFULGI_00020120 475da9cfc9e306276399580518bf9d88 165 TIGRFAM TIGR02087 LEUD_arch: 3-isopropylmalate dehydratase, small subunit 5 159 1.1E-66 T 01-11-2018 IPR011827 Hydrolyase LeuD/HacB/DmdB GO:0016836 KEGG: 00290+4.2.1.33 AFULGI_00020120 475da9cfc9e306276399580518bf9d88 165 SUPERFAMILY SSF52016 3 161 1.86E-52 T 01-11-2018 AFULGI_00020120 475da9cfc9e306276399580518bf9d88 165 Hamap MF_01032 Methanogen homoaconitase small subunit [hacB]. 3 162 40.624 T 01-11-2018 IPR011827 Hydrolyase LeuD/HacB/DmdB GO:0016836 KEGG: 00290+4.2.1.33 AFULGI_00020120 475da9cfc9e306276399580518bf9d88 165 Gene3D G3DSA:3.20.19.10 1 163 9.8E-58 T 01-11-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 AFULGI_00020120 475da9cfc9e306276399580518bf9d88 165 Pfam PF00694 Aconitase C-terminal domain 42 101 1.4E-20 T 01-11-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 AFULGI_00010430 74d6f27d5e5b5278c0a4b29b1e1b2c01 510 PIRSF PIRSF006429 8 510 6.1E-145 T 01-11-2018 IPR024188 Glutamate synthase large subunit-like protein AFULGI_00010430 74d6f27d5e5b5278c0a4b29b1e1b2c01 510 SUPERFAMILY SSF51395 96 494 1.17E-118 T 01-11-2018 AFULGI_00010430 74d6f27d5e5b5278c0a4b29b1e1b2c01 510 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 54 65 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFULGI_00010430 74d6f27d5e5b5278c0a4b29b1e1b2c01 510 Pfam PF00037 4Fe-4S binding domain 50 69 2.3E-6 T 01-11-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFULGI_00010430 74d6f27d5e5b5278c0a4b29b1e1b2c01 510 PIRSF PIRSF500061 5 510 2.3E-203 T 01-11-2018 AFULGI_00010430 74d6f27d5e5b5278c0a4b29b1e1b2c01 510 Pfam PF01645 Conserved region in glutamate synthase 112 478 5.8E-147 T 01-11-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 AFULGI_00010430 74d6f27d5e5b5278c0a4b29b1e1b2c01 510 Gene3D G3DSA:3.20.20.70 134 502 1.6E-131 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFULGI_00010430 74d6f27d5e5b5278c0a4b29b1e1b2c01 510 SUPERFAMILY SSF54862 12 147 1.23E-17 T 01-11-2018 AFULGI_00010430 74d6f27d5e5b5278c0a4b29b1e1b2c01 510 Gene3D G3DSA:3.30.70.20 6 88 1.7E-8 T 01-11-2018 AFULGI_00010070 b2fca893616c9f53de87bb8fa4f101fc 240 Pfam PF01979 Amidohydrolase family 42 195 4.6E-11 T 01-11-2018 IPR006680 Amidohydrolase-related GO:0016787 AFULGI_00010070 b2fca893616c9f53de87bb8fa4f101fc 240 SUPERFAMILY SSF51556 2 230 2.92E-53 T 01-11-2018 IPR032466 Metal-dependent hydrolase AFULGI_00010070 b2fca893616c9f53de87bb8fa4f101fc 240 Gene3D G3DSA:3.20.20.140 1 239 1.2E-60 T 01-11-2018 AFULGI_00022120 4d0c446f8fde610b0f65759cd941c184 245 Gene3D G3DSA:3.60.21.10 1 239 3.7E-22 T 01-11-2018 IPR029052 Metallo-dependent phosphatase-like AFULGI_00022120 4d0c446f8fde610b0f65759cd941c184 245 SUPERFAMILY SSF56300 1 242 9.86E-30 T 01-11-2018 AFULGI_00010230 f0d50855539c8ca9778591cec404cb63 290 TIGRFAM TIGR01122 ilvE_I: branched-chain amino acid aminotransferase 5 284 1.0E-123 T 01-11-2018 IPR005785 Branched-chain amino acid aminotransferase I GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767 AFULGI_00010230 f0d50855539c8ca9778591cec404cb63 290 Gene3D G3DSA:3.30.470.10 1 125 3.3E-57 T 01-11-2018 AFULGI_00010230 f0d50855539c8ca9778591cec404cb63 290 Gene3D G3DSA:3.20.10.10 126 285 1.7E-56 T 01-11-2018 AFULGI_00010230 f0d50855539c8ca9778591cec404cb63 290 Pfam PF01063 Amino-transferase class IV 30 254 2.1E-59 T 01-11-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 AFULGI_00010230 f0d50855539c8ca9778591cec404cb63 290 ProSitePatterns PS00770 Aminotransferases class-IV signature. 183 211 - T 01-11-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824 Reactome: R-HSA-70895 AFULGI_00010230 f0d50855539c8ca9778591cec404cb63 290 SUPERFAMILY SSF56752 3 280 3.92E-96 T 01-11-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 AFULGI_00021160 eb2d757f95efa3a0f014ef6d5318ee71 343 TIGRFAM TIGR01898 cas_TM1791_cmr6: CRISPR type III-B/RAMP module RAMP protein Cmr6 101 338 9.9E-82 T 01-11-2018 IPR010172 CRISPR-associated protein, TM1791 AFULGI_00021160 eb2d757f95efa3a0f014ef6d5318ee71 343 Pfam PF03787 RAMP superfamily 104 337 4.8E-14 T 01-11-2018 IPR005537 CRISPR type III-associated RAMP protein AFULGI_00019620 ba742a574426881fdc911c6140daebcf 71 Gene3D G3DSA:4.10.1150.10 1 71 7.0E-14 T 01-11-2018 IPR024069 AF2212-like domain superfamily AFULGI_00019620 ba742a574426881fdc911c6140daebcf 71 Pfam PF01954 Protein of unknown function DUF104 1 53 3.3E-17 T 01-11-2018 IPR008203 Uncharacterised protein family UPF0165 AFULGI_00019620 ba742a574426881fdc911c6140daebcf 71 SUPERFAMILY SSF141694 1 45 1.6E-12 T 01-11-2018 AFULGI_00000190 f8cd7c7ff9a629c7d220aebc9eea9ba8 323 Gene3D G3DSA:3.30.565.10 187 323 1.7E-29 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFULGI_00000190 f8cd7c7ff9a629c7d220aebc9eea9ba8 323 SUPERFAMILY SSF55874 187 322 2.49E-27 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFULGI_00000190 f8cd7c7ff9a629c7d220aebc9eea9ba8 323 Gene3D G3DSA:3.30.450.20 2 123 3.5E-12 T 01-11-2018 AFULGI_00000190 f8cd7c7ff9a629c7d220aebc9eea9ba8 323 SUPERFAMILY SSF55785 5 108 4.01E-12 T 01-11-2018 IPR035965 PAS domain superfamily AFULGI_00000190 f8cd7c7ff9a629c7d220aebc9eea9ba8 323 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 222 322 1.2E-19 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFULGI_00000190 f8cd7c7ff9a629c7d220aebc9eea9ba8 323 SMART SM00091 3 66 1.7E-6 T 01-11-2018 IPR000014 PAS domain AFULGI_00000190 f8cd7c7ff9a629c7d220aebc9eea9ba8 323 Pfam PF13426 PAS domain 13 108 5.8E-8 T 01-11-2018 IPR000014 PAS domain AFULGI_00000190 f8cd7c7ff9a629c7d220aebc9eea9ba8 323 SMART SM00387 219 323 2.8E-29 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFULGI_00000190 f8cd7c7ff9a629c7d220aebc9eea9ba8 323 PRINTS PR00344 Bacterial sensor protein C-terminal signature 285 303 2.3E-10 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFULGI_00000190 f8cd7c7ff9a629c7d220aebc9eea9ba8 323 PRINTS PR00344 Bacterial sensor protein C-terminal signature 255 269 2.3E-10 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFULGI_00000190 f8cd7c7ff9a629c7d220aebc9eea9ba8 323 PRINTS PR00344 Bacterial sensor protein C-terminal signature 273 283 2.3E-10 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFULGI_00000190 f8cd7c7ff9a629c7d220aebc9eea9ba8 323 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 3 116 7.1E-10 T 01-11-2018 IPR000014 PAS domain AFULGI_00009950 f3269dc5dec0739511798b9199b38547 257 Gene3D G3DSA:3.40.50.720 3 256 8.2E-90 T 01-11-2018 AFULGI_00009950 f3269dc5dec0739511798b9199b38547 257 SUPERFAMILY SSF51735 1 257 8.63E-41 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily AFULGI_00009950 f3269dc5dec0739511798b9199b38547 257 SUPERFAMILY SSF55347 120 227 3.27E-30 T 01-11-2018 AFULGI_00009950 f3269dc5dec0739511798b9199b38547 257 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 142 159 - T 01-11-2018 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AFULGI_00009950 f3269dc5dec0739511798b9199b38547 257 PIRSF PIRSF000161 1 257 3.5E-82 T 01-11-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AFULGI_00009950 f3269dc5dec0739511798b9199b38547 257 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 1 118 8.7E-36 T 01-11-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AFULGI_00009950 f3269dc5dec0739511798b9199b38547 257 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 121 256 9.5E-42 T 01-11-2018 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AFULGI_00009950 f3269dc5dec0739511798b9199b38547 257 Gene3D G3DSA:3.30.360.10 120 225 8.2E-90 T 01-11-2018 AFULGI_00009950 f3269dc5dec0739511798b9199b38547 257 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 1 257 7.2E-107 T 01-11-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AFULGI_00009950 f3269dc5dec0739511798b9199b38547 257 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 1 257 34.397 T 01-11-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AFULGI_00013850 b3db79daafe22f291b9b05981073ddef 213 Gene3D G3DSA:3.40.50.880 1 212 4.2E-51 T 01-11-2018 IPR029062 Class I glutamine amidotransferase-like AFULGI_00013850 b3db79daafe22f291b9b05981073ddef 213 Pfam PF00117 Glutamine amidotransferase class-I 35 168 3.6E-16 T 01-11-2018 IPR017926 Glutamine amidotransferase AFULGI_00013850 b3db79daafe22f291b9b05981073ddef 213 SUPERFAMILY SSF52317 19 181 2.22E-40 T 01-11-2018 IPR029062 Class I glutamine amidotransferase-like AFULGI_00020620 57e1b80a1e887cb4269229aab717839d 157 SUPERFAMILY SSF52335 2 154 1.96E-34 T 01-11-2018 IPR036914 Methylglyoxal synthase-like domain superfamily AFULGI_00020620 57e1b80a1e887cb4269229aab717839d 157 SMART SM00851 12 114 6.4E-21 T 01-11-2018 IPR011607 Methylglyoxal synthase-like domain AFULGI_00020620 57e1b80a1e887cb4269229aab717839d 157 Gene3D G3DSA:3.40.50.1380 1 154 6.8E-37 T 01-11-2018 IPR036914 Methylglyoxal synthase-like domain superfamily AFULGI_00020620 57e1b80a1e887cb4269229aab717839d 157 Pfam PF02142 MGS-like domain 13 112 4.7E-19 T 01-11-2018 IPR011607 Methylglyoxal synthase-like domain AFULGI_00014700 785fa8d36206f2b95ff92c545fe95ccd 251 Pfam PF00005 ABC transporter 21 176 4.8E-32 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFULGI_00014700 785fa8d36206f2b95ff92c545fe95ccd 251 SMART SM00382 29 223 5.7E-15 T 01-11-2018 IPR003593 AAA+ ATPase domain AFULGI_00014700 785fa8d36206f2b95ff92c545fe95ccd 251 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFULGI_00014700 785fa8d36206f2b95ff92c545fe95ccd 251 SUPERFAMILY SSF52540 3 238 2.72E-65 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00014700 785fa8d36206f2b95ff92c545fe95ccd 251 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 5 251 2.0E-107 T 01-11-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 AFULGI_00014700 785fa8d36206f2b95ff92c545fe95ccd 251 Gene3D G3DSA:3.40.50.300 1 249 1.3E-72 T 01-11-2018 AFULGI_00020740 add812d910e43f420f72498be0e31843 775 Pfam PF02687 FtsX-like permease family 674 765 1.9E-11 T 01-11-2018 IPR003838 ABC transporter permease protein domain GO:0016020 AFULGI_00020740 add812d910e43f420f72498be0e31843 775 Pfam PF02687 FtsX-like permease family 287 378 1.2E-8 T 01-11-2018 IPR003838 ABC transporter permease protein domain GO:0016020 AFULGI_00021620 5fd657b7bc1ada23ed90276be39ddfad 176 ProSitePatterns PS00475 Ribosomal protein L15 signature. 140 170 - T 01-11-2018 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00021620 5fd657b7bc1ada23ed90276be39ddfad 176 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 26 174 4.5E-22 T 01-11-2018 IPR021131 Ribosomal protein L18e/L15P AFULGI_00021620 5fd657b7bc1ada23ed90276be39ddfad 176 SUPERFAMILY SSF52080 2 174 2.9E-18 T 01-11-2018 IPR036227 Ribosomal L18e/L15P superfamily AFULGI_00021620 5fd657b7bc1ada23ed90276be39ddfad 176 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 1 176 13.216 T 01-11-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 AFULGI_00021620 5fd657b7bc1ada23ed90276be39ddfad 176 Gene3D G3DSA:4.10.990.10 2 52 7.7E-22 T 01-11-2018 IPR027386 50S ribosomal protein L15, N-terminal AFULGI_00021620 5fd657b7bc1ada23ed90276be39ddfad 176 Gene3D G3DSA:3.100.10.10 96 176 2.9E-19 T 01-11-2018 AFULGI_00011360 8c7fb22d749beaa6ae9ed0d67205f1e8 656 Gene3D G3DSA:3.30.70.1110 142 224 2.0E-15 T 01-11-2018 IPR037052 Chemotaxis protein CheA, P2 response regulator-binding domain superfamily AFULGI_00011360 8c7fb22d749beaa6ae9ed0d67205f1e8 656 Gene3D G3DSA:1.20.120.160 1 139 6.9E-38 T 01-11-2018 IPR036641 HPT domain superfamily GO:0000160 AFULGI_00011360 8c7fb22d749beaa6ae9ed0d67205f1e8 656 Pfam PF07194 P2 response regulator binding domain 146 222 1.2E-19 T 01-11-2018 IPR010808 Chemotaxis protein CheA, P2 response regulator-binding GO:0000155|GO:0000160|GO:0004673|GO:0006928 AFULGI_00011360 8c7fb22d749beaa6ae9ed0d67205f1e8 656 SUPERFAMILY SSF47226 5 120 4.58E-31 T 01-11-2018 IPR036641 HPT domain superfamily GO:0000160 AFULGI_00011360 8c7fb22d749beaa6ae9ed0d67205f1e8 656 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 380 520 2.8E-20 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFULGI_00011360 8c7fb22d749beaa6ae9ed0d67205f1e8 656 SUPERFAMILY SSF47384 274 334 7.45E-16 T 01-11-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFULGI_00011360 8c7fb22d749beaa6ae9ed0d67205f1e8 656 SUPERFAMILY SSF55874 335 518 6.81E-41 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFULGI_00011360 8c7fb22d749beaa6ae9ed0d67205f1e8 656 Gene3D G3DSA:2.30.30.40 521 646 3.8E-36 T 01-11-2018 AFULGI_00011360 8c7fb22d749beaa6ae9ed0d67205f1e8 656 Pfam PF02895 Signal transducing histidine kinase, homodimeric domain 275 333 4.1E-13 T 01-11-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 AFULGI_00011360 8c7fb22d749beaa6ae9ed0d67205f1e8 656 SUPERFAMILY SSF50341 520 650 2.49E-31 T 01-11-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 AFULGI_00011360 8c7fb22d749beaa6ae9ed0d67205f1e8 656 SMART SM00260 513 650 6.9E-45 T 01-11-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 AFULGI_00011360 8c7fb22d749beaa6ae9ed0d67205f1e8 656 Gene3D G3DSA:2.40.50.180 544 605 3.8E-36 T 01-11-2018 AFULGI_00011360 8c7fb22d749beaa6ae9ed0d67205f1e8 656 Gene3D G3DSA:3.30.565.10 334 520 3.1E-62 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFULGI_00011360 8c7fb22d749beaa6ae9ed0d67205f1e8 656 SUPERFAMILY SSF55052 145 223 3.4E-17 T 01-11-2018 IPR035891 CheY-binding domain of CheA AFULGI_00011360 8c7fb22d749beaa6ae9ed0d67205f1e8 656 SMART SM00387 378 521 2.5E-30 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFULGI_00011360 8c7fb22d749beaa6ae9ed0d67205f1e8 656 SMART SM00073 5 100 9.5E-39 T 01-11-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 AFULGI_00011360 8c7fb22d749beaa6ae9ed0d67205f1e8 656 Gene3D G3DSA:1.10.287.560 274 333 4.8E-20 T 01-11-2018 IPR037006 Histidine kinase CheA-like, homodimeric domain superfamily GO:0000155|GO:0006935 AFULGI_00011360 8c7fb22d749beaa6ae9ed0d67205f1e8 656 PRINTS PR00344 Bacterial sensor protein C-terminal signature 505 518 6.1E-15 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFULGI_00011360 8c7fb22d749beaa6ae9ed0d67205f1e8 656 PRINTS PR00344 Bacterial sensor protein C-terminal signature 423 437 6.1E-15 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFULGI_00011360 8c7fb22d749beaa6ae9ed0d67205f1e8 656 PRINTS PR00344 Bacterial sensor protein C-terminal signature 481 499 6.1E-15 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFULGI_00011360 8c7fb22d749beaa6ae9ed0d67205f1e8 656 PRINTS PR00344 Bacterial sensor protein C-terminal signature 465 475 6.1E-15 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFULGI_00011360 8c7fb22d749beaa6ae9ed0d67205f1e8 656 SMART SM01231 273 333 2.7E-19 T 01-11-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 AFULGI_00011360 8c7fb22d749beaa6ae9ed0d67205f1e8 656 Pfam PF01627 Hpt domain 8 96 3.8E-20 T 01-11-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 AFULGI_00011360 8c7fb22d749beaa6ae9ed0d67205f1e8 656 Pfam PF01584 CheW-like domain 527 650 4.4E-24 T 01-11-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 AFULGI_00017980 2789ddf8d018393896d4ef763290824a 109 Pfam PF12840 Helix-turn-helix domain 33 87 1.0E-9 T 01-11-2018 AFULGI_00017980 2789ddf8d018393896d4ef763290824a 109 SUPERFAMILY SSF46785 32 104 9.87E-17 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00017980 2789ddf8d018393896d4ef763290824a 109 SMART SM00418 31 107 1.1E-15 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFULGI_00017980 2789ddf8d018393896d4ef763290824a 109 Gene3D G3DSA:1.10.10.10 9 106 7.5E-23 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00001320 cbcd7f7a7e98fbaf9d85d2224e2e6ed9 148 Gene3D G3DSA:1.10.12.20 3 68 6.5E-18 T 01-11-2018 AFULGI_00001320 cbcd7f7a7e98fbaf9d85d2224e2e6ed9 148 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 33 59 1.6E-5 T 01-11-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal AFULGI_00001320 cbcd7f7a7e98fbaf9d85d2224e2e6ed9 148 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 67 130 1.1E-7 T 01-11-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal AFULGI_00001320 cbcd7f7a7e98fbaf9d85d2224e2e6ed9 148 SUPERFAMILY SSF50249 10 137 4.63E-25 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold AFULGI_00018880 b5a84527f8dc5b81d21c90f4487cdfb5 441 Gene3D G3DSA:3.30.70.150 3 133 1.1E-42 T 01-11-2018 IPR036422 RuBisCO large subunit, N-terminal domain superfamily GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 AFULGI_00018880 b5a84527f8dc5b81d21c90f4487cdfb5 441 Pfam PF02788 Ribulose bisphosphate carboxylase large chain, N-terminal domain 9 129 3.9E-47 T 01-11-2018 IPR017443 Ribulose bisphosphate carboxylase, large subunit, ferrodoxin-like N-terminal GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 AFULGI_00018880 b5a84527f8dc5b81d21c90f4487cdfb5 441 Hamap MF_01133 Ribulose bisphosphate carboxylase [rbcL]. 8 436 52.679 T 01-11-2018 IPR017712 Ribulose bisphosphate carboxylase, type III GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 AFULGI_00018880 b5a84527f8dc5b81d21c90f4487cdfb5 441 SUPERFAMILY SSF54966 7 134 4.45E-40 T 01-11-2018 IPR036422 RuBisCO large subunit, N-terminal domain superfamily GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 AFULGI_00018880 b5a84527f8dc5b81d21c90f4487cdfb5 441 TIGRFAM TIGR03326 rubisco_III: ribulose bisphosphate carboxylase, type III 9 435 5.3E-229 T 01-11-2018 IPR017712 Ribulose bisphosphate carboxylase, type III GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 AFULGI_00018880 b5a84527f8dc5b81d21c90f4487cdfb5 441 SUPERFAMILY SSF51649 133 438 1.83E-106 T 01-11-2018 IPR036376 Ribulose bisphosphate carboxylase, large subunit, C-terminal domain superfamily GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 AFULGI_00018880 b5a84527f8dc5b81d21c90f4487cdfb5 441 Gene3D G3DSA:3.20.20.110 134 435 2.6E-120 T 01-11-2018 IPR036376 Ribulose bisphosphate carboxylase, large subunit, C-terminal domain superfamily GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 AFULGI_00018880 b5a84527f8dc5b81d21c90f4487cdfb5 441 Pfam PF00016 Ribulose bisphosphate carboxylase large chain, catalytic domain 143 435 6.6E-97 T 01-11-2018 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 AFULGI_00010920 905d2b3794fb3083fb20c81aaf3d4cec 258 Pfam PF13412 Winged helix-turn-helix DNA-binding 9 54 8.9E-13 T 01-11-2018 AFULGI_00010920 905d2b3794fb3083fb20c81aaf3d4cec 258 PIRSF PIRSF004955 1 258 6.3E-102 T 01-11-2018 IPR012015 Uncharacterised conserved protein HTH transcriptional regulator, archaea AFULGI_00010920 905d2b3794fb3083fb20c81aaf3d4cec 258 SMART SM00419 17 66 2.3E-11 T 01-11-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 AFULGI_00010920 905d2b3794fb3083fb20c81aaf3d4cec 258 Gene3D G3DSA:1.10.10.10 7 86 4.4E-10 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00010920 905d2b3794fb3083fb20c81aaf3d4cec 258 SUPERFAMILY SSF46785 9 112 1.7E-13 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00004410 69eb8da5e4f7430a143087db1e4afd93 131 Gene3D G3DSA:1.10.12.20 2 61 3.1E-7 T 01-11-2018 AFULGI_00004410 69eb8da5e4f7430a143087db1e4afd93 131 SUPERFAMILY SSF50249 6 122 6.0E-22 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold AFULGI_00004410 69eb8da5e4f7430a143087db1e4afd93 131 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 23 54 9.4E-7 T 01-11-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal AFULGI_00004410 69eb8da5e4f7430a143087db1e4afd93 131 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 58 114 1.5E-9 T 01-11-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal AFULGI_00018920 5cb825fcb961bb635ee15cefcaac72b0 409 Hamap MF_00125 ATP phosphoribosyltransferase regulatory subunit [hisZ]. 15 362 24.716 T 01-11-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 AFULGI_00018920 5cb825fcb961bb635ee15cefcaac72b0 409 Gene3D G3DSA:3.30.930.10 1 318 2.3E-100 T 01-11-2018 AFULGI_00018920 5cb825fcb961bb635ee15cefcaac72b0 409 Pfam PF13393 Histidyl-tRNA synthetase 8 309 4.6E-71 T 01-11-2018 AFULGI_00018920 5cb825fcb961bb635ee15cefcaac72b0 409 TIGRFAM TIGR00443 hisZ_biosyn_reg: ATP phosphoribosyltransferase, regulatory subunit 10 313 1.1E-81 T 01-11-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 AFULGI_00018920 5cb825fcb961bb635ee15cefcaac72b0 409 SUPERFAMILY SSF55681 3 311 5.77E-85 T 01-11-2018 AFULGI_00018920 5cb825fcb961bb635ee15cefcaac72b0 409 PIRSF PIRSF001549 1 409 1.1E-126 T 01-11-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 AFULGI_00018920 5cb825fcb961bb635ee15cefcaac72b0 409 Pfam PF03129 Anticodon binding domain 323 409 3.6E-14 T 01-11-2018 IPR004154 Anticodon-binding AFULGI_00018920 5cb825fcb961bb635ee15cefcaac72b0 409 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 1 409 30.439 T 01-11-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 AFULGI_00018920 5cb825fcb961bb635ee15cefcaac72b0 409 Gene3D G3DSA:3.40.50.800 320 406 2.0E-21 T 01-11-2018 IPR036621 Anticodon-binding domain superfamily AFULGI_00018920 5cb825fcb961bb635ee15cefcaac72b0 409 SUPERFAMILY SSF52954 322 408 7.69E-21 T 01-11-2018 AFULGI_00018920 5cb825fcb961bb635ee15cefcaac72b0 409 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 5 399 2.1E-123 T 01-11-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 AFULGI_00003140 cc8ccf43d6eb7bccb002b1e06c4ab42b 70 Gene3D G3DSA:4.10.1150.10 6 67 3.0E-20 T 01-11-2018 IPR024069 AF2212-like domain superfamily AFULGI_00003140 cc8ccf43d6eb7bccb002b1e06c4ab42b 70 Pfam PF01954 Protein of unknown function DUF104 6 61 1.5E-21 T 01-11-2018 IPR008203 Uncharacterised protein family UPF0165 AFULGI_00003140 cc8ccf43d6eb7bccb002b1e06c4ab42b 70 SUPERFAMILY SSF141694 6 60 4.45E-16 T 01-11-2018 AFULGI_00001820 a3530546ce6e051403a52669c6602972 662 Pfam PF00501 AMP-binding enzyme 111 533 1.1E-49 T 01-11-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFULGI_00001820 a3530546ce6e051403a52669c6602972 662 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 47 103 4.3E-13 T 01-11-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 AFULGI_00001820 a3530546ce6e051403a52669c6602972 662 Gene3D G3DSA:3.40.50.12780 67 527 4.8E-59 T 01-11-2018 AFULGI_00001820 a3530546ce6e051403a52669c6602972 662 ProSitePatterns PS00455 Putative AMP-binding domain signature. 276 287 - T 01-11-2018 IPR020845 AMP-binding, conserved site AFULGI_00001820 a3530546ce6e051403a52669c6602972 662 SUPERFAMILY SSF56801 33 628 6.41E-118 T 01-11-2018 AFULGI_00001820 a3530546ce6e051403a52669c6602972 662 Gene3D G3DSA:3.30.300.30 530 649 1.5E-7 T 01-11-2018 AFULGI_00001820 a3530546ce6e051403a52669c6602972 662 TIGRFAM TIGR01217 ac_ac_CoA_syn: acetoacetate-CoA ligase 3 645 6.6E-217 T 01-11-2018 IPR005914 Acetoacetyl-CoA synthase GO:0006629|GO:0030729 KEGG: 00280+6.2.1.16|KEGG: 00650+6.2.1.16|Reactome: R-HSA-77111 AFULGI_00015670 bdee2eec6fbddfd1617ac1854ca4226e 438 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 341 436 1.2E-19 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFULGI_00015670 bdee2eec6fbddfd1617ac1854ca4226e 438 SMART SM00091 3 69 2.1E-8 T 01-11-2018 IPR000014 PAS domain AFULGI_00015670 bdee2eec6fbddfd1617ac1854ca4226e 438 SMART SM00091 126 191 8.4E-11 T 01-11-2018 IPR000014 PAS domain AFULGI_00015670 bdee2eec6fbddfd1617ac1854ca4226e 438 SUPERFAMILY SSF55785 111 236 8.54E-26 T 01-11-2018 IPR035965 PAS domain superfamily AFULGI_00015670 bdee2eec6fbddfd1617ac1854ca4226e 438 SMART SM00086 198 238 110.0 T 01-11-2018 IPR001610 PAC motif AFULGI_00015670 bdee2eec6fbddfd1617ac1854ca4226e 438 SMART SM00086 74 114 0.24 T 01-11-2018 IPR001610 PAC motif AFULGI_00015670 bdee2eec6fbddfd1617ac1854ca4226e 438 Gene3D G3DSA:3.30.450.20 2 112 2.4E-21 T 01-11-2018 AFULGI_00015670 bdee2eec6fbddfd1617ac1854ca4226e 438 Gene3D G3DSA:3.30.450.20 113 236 5.6E-25 T 01-11-2018 AFULGI_00015670 bdee2eec6fbddfd1617ac1854ca4226e 438 SUPERFAMILY SSF55874 310 437 6.16E-28 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFULGI_00015670 bdee2eec6fbddfd1617ac1854ca4226e 438 Pfam PF08447 PAS fold 148 226 7.9E-12 T 01-11-2018 IPR013655 PAS fold-3 GO:0005515 AFULGI_00015670 bdee2eec6fbddfd1617ac1854ca4226e 438 Pfam PF08447 PAS fold 27 103 3.8E-10 T 01-11-2018 IPR013655 PAS fold-3 GO:0005515 AFULGI_00015670 bdee2eec6fbddfd1617ac1854ca4226e 438 SMART SM00387 337 438 3.0E-24 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFULGI_00015670 bdee2eec6fbddfd1617ac1854ca4226e 438 PRINTS PR00344 Bacterial sensor protein C-terminal signature 423 436 1.5E-8 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFULGI_00015670 bdee2eec6fbddfd1617ac1854ca4226e 438 PRINTS PR00344 Bacterial sensor protein C-terminal signature 399 417 1.5E-8 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFULGI_00015670 bdee2eec6fbddfd1617ac1854ca4226e 438 PRINTS PR00344 Bacterial sensor protein C-terminal signature 372 386 1.5E-8 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFULGI_00015670 bdee2eec6fbddfd1617ac1854ca4226e 438 SUPERFAMILY SSF55785 15 123 2.74E-24 T 01-11-2018 IPR035965 PAS domain superfamily AFULGI_00015670 bdee2eec6fbddfd1617ac1854ca4226e 438 Gene3D G3DSA:3.30.565.10 300 438 2.6E-29 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFULGI_00015670 bdee2eec6fbddfd1617ac1854ca4226e 438 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 122 245 4.8E-32 T 01-11-2018 IPR000014 PAS domain AFULGI_00015670 bdee2eec6fbddfd1617ac1854ca4226e 438 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 5 121 2.5E-20 T 01-11-2018 IPR000014 PAS domain AFULGI_00025480 87690e1f05c465dd18d3fbf8303fdc8c 362 SUPERFAMILY SSF52540 70 354 1.35E-75 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00025480 87690e1f05c465dd18d3fbf8303fdc8c 362 Pfam PF00270 DEAD/DEAH box helicase 25 189 2.3E-50 T 01-11-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 AFULGI_00025480 87690e1f05c465dd18d3fbf8303fdc8c 362 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 149 157 - T 01-11-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site AFULGI_00025480 87690e1f05c465dd18d3fbf8303fdc8c 362 SMART SM00490 252 333 1.9E-31 T 01-11-2018 IPR001650 Helicase, C-terminal AFULGI_00025480 87690e1f05c465dd18d3fbf8303fdc8c 362 Pfam PF00271 Helicase conserved C-terminal domain 226 333 9.0E-29 T 01-11-2018 IPR001650 Helicase, C-terminal AFULGI_00025480 87690e1f05c465dd18d3fbf8303fdc8c 362 SMART SM00487 20 217 3.6E-67 T 01-11-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFULGI_00025480 87690e1f05c465dd18d3fbf8303fdc8c 362 Gene3D G3DSA:3.40.50.300 210 362 6.3E-49 T 01-11-2018 AFULGI_00025480 87690e1f05c465dd18d3fbf8303fdc8c 362 Gene3D G3DSA:3.40.50.300 1 207 8.9E-79 T 01-11-2018 AFULGI_00014000 e95e4ada7f9ce3c67e2d50e0a4fe3978 162 SUPERFAMILY SSF89028 5 153 3.27E-35 T 01-11-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 AFULGI_00014000 e95e4ada7f9ce3c67e2d50e0a4fe3978 162 Gene3D G3DSA:1.20.1200.10 8 158 1.0E-32 T 01-11-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 AFULGI_00014000 e95e4ada7f9ce3c67e2d50e0a4fe3978 162 Pfam PF01923 Cobalamin adenosyltransferase 5 151 2.0E-31 T 01-11-2018 IPR016030 Cobalamin adenosyltransferase-like KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 AFULGI_00014000 e95e4ada7f9ce3c67e2d50e0a4fe3978 162 ProDom PD007457 TRANSFERASE ADENOSYLTRANSFERASE COBALAMIN ATP:COBIALAMIN ADENOSYLTRANSFERASE PDUO TYPE RELATED ACIDURIA YVQK 14 110 1.0E-50 T 01-11-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 AFULGI_00015270 7cd15dbf60812885c4bb52f3fde66207 2419 SUPERFAMILY SSF51126 29 271 1.4E-33 T 01-11-2018 IPR011050 Pectin lyase fold/virulence factor AFULGI_00015270 7cd15dbf60812885c4bb52f3fde66207 2419 Gene3D G3DSA:2.60.40.10 313 409 6.0E-10 T 01-11-2018 IPR013783 Immunoglobulin-like fold AFULGI_00015270 7cd15dbf60812885c4bb52f3fde66207 2419 TIGRFAM TIGR03804 para_beta_helix: parallel beta-helix repeat 857 900 6.2E-5 T 01-11-2018 IPR022441 Parallel beta-helix repeat-2 Reactome: R-HSA-8951664|Reactome: R-HSA-983168 AFULGI_00015270 7cd15dbf60812885c4bb52f3fde66207 2419 SMART SM00060 318 397 7.1E-9 T 01-11-2018 IPR003961 Fibronectin type III GO:0005515 AFULGI_00015270 7cd15dbf60812885c4bb52f3fde66207 2419 SMART SM00722 129 284 1.3E-7 T 01-11-2018 IPR006633 Carbohydrate-binding/sugar hydrolysis domain AFULGI_00015270 7cd15dbf60812885c4bb52f3fde66207 2419 SMART SM00722 804 922 0.0029 T 01-11-2018 IPR006633 Carbohydrate-binding/sugar hydrolysis domain AFULGI_00015270 7cd15dbf60812885c4bb52f3fde66207 2419 SMART SM00722 512 683 0.01 T 01-11-2018 IPR006633 Carbohydrate-binding/sugar hydrolysis domain AFULGI_00015270 7cd15dbf60812885c4bb52f3fde66207 2419 SMART SM00722 923 1033 0.85 T 01-11-2018 IPR006633 Carbohydrate-binding/sugar hydrolysis domain AFULGI_00015270 7cd15dbf60812885c4bb52f3fde66207 2419 SMART SM00722 22 128 84.0 T 01-11-2018 IPR006633 Carbohydrate-binding/sugar hydrolysis domain AFULGI_00015270 7cd15dbf60812885c4bb52f3fde66207 2419 SMART SM00722 380 505 14.0 T 01-11-2018 IPR006633 Carbohydrate-binding/sugar hydrolysis domain AFULGI_00015270 7cd15dbf60812885c4bb52f3fde66207 2419 SUPERFAMILY SSF51126 405 733 9.43E-29 T 01-11-2018 IPR011050 Pectin lyase fold/virulence factor AFULGI_00015270 7cd15dbf60812885c4bb52f3fde66207 2419 Gene3D G3DSA:2.160.20.10 769 911 9.9E-12 T 01-11-2018 IPR012334 Pectin lyase fold AFULGI_00015270 7cd15dbf60812885c4bb52f3fde66207 2419 SMART SM00710 836 862 7.0 T 01-11-2018 IPR006626 Parallel beta-helix repeat AFULGI_00015270 7cd15dbf60812885c4bb52f3fde66207 2419 SMART SM00710 863 885 710.0 T 01-11-2018 IPR006626 Parallel beta-helix repeat AFULGI_00015270 7cd15dbf60812885c4bb52f3fde66207 2419 SMART SM00710 581 603 3400.0 T 01-11-2018 IPR006626 Parallel beta-helix repeat AFULGI_00015270 7cd15dbf60812885c4bb52f3fde66207 2419 SMART SM00710 886 923 2100.0 T 01-11-2018 IPR006626 Parallel beta-helix repeat AFULGI_00015270 7cd15dbf60812885c4bb52f3fde66207 2419 SMART SM00710 685 706 2300.0 T 01-11-2018 IPR006626 Parallel beta-helix repeat AFULGI_00015270 7cd15dbf60812885c4bb52f3fde66207 2419 SMART SM00710 180 202 3.5 T 01-11-2018 IPR006626 Parallel beta-helix repeat AFULGI_00015270 7cd15dbf60812885c4bb52f3fde66207 2419 SMART SM00710 107 129 2.1 T 01-11-2018 IPR006626 Parallel beta-helix repeat AFULGI_00015270 7cd15dbf60812885c4bb52f3fde66207 2419 SMART SM00710 958 980 1300.0 T 01-11-2018 IPR006626 Parallel beta-helix repeat AFULGI_00015270 7cd15dbf60812885c4bb52f3fde66207 2419 SMART SM00710 157 178 81.0 T 01-11-2018 IPR006626 Parallel beta-helix repeat AFULGI_00015270 7cd15dbf60812885c4bb52f3fde66207 2419 SMART SM00710 535 555 500.0 T 01-11-2018 IPR006626 Parallel beta-helix repeat AFULGI_00015270 7cd15dbf60812885c4bb52f3fde66207 2419 SMART SM00710 924 957 2100.0 T 01-11-2018 IPR006626 Parallel beta-helix repeat AFULGI_00015270 7cd15dbf60812885c4bb52f3fde66207 2419 SMART SM00710 657 684 2000.0 T 01-11-2018 IPR006626 Parallel beta-helix repeat AFULGI_00015270 7cd15dbf60812885c4bb52f3fde66207 2419 SMART SM00710 610 635 1400.0 T 01-11-2018 IPR006626 Parallel beta-helix repeat AFULGI_00015270 7cd15dbf60812885c4bb52f3fde66207 2419 SMART SM00710 485 516 620.0 T 01-11-2018 IPR006626 Parallel beta-helix repeat AFULGI_00015270 7cd15dbf60812885c4bb52f3fde66207 2419 SMART SM00710 135 156 4.8 T 01-11-2018 IPR006626 Parallel beta-helix repeat AFULGI_00015270 7cd15dbf60812885c4bb52f3fde66207 2419 SMART SM00710 791 812 630.0 T 01-11-2018 IPR006626 Parallel beta-helix repeat AFULGI_00015270 7cd15dbf60812885c4bb52f3fde66207 2419 Pfam PF05048 Periplasmic copper-binding protein (NosD) 801 1044 1.3E-48 T 01-11-2018 IPR007742 Periplasmic copper-binding protein NosD, beta helix domain Reactome: R-HSA-8951664|Reactome: R-HSA-983168 AFULGI_00015270 7cd15dbf60812885c4bb52f3fde66207 2419 Pfam PF05048 Periplasmic copper-binding protein (NosD) 66 273 6.3E-30 T 01-11-2018 IPR007742 Periplasmic copper-binding protein NosD, beta helix domain Reactome: R-HSA-8951664|Reactome: R-HSA-983168 AFULGI_00015270 7cd15dbf60812885c4bb52f3fde66207 2419 Pfam PF05048 Periplasmic copper-binding protein (NosD) 436 636 4.3E-6 T 01-11-2018 IPR007742 Periplasmic copper-binding protein NosD, beta helix domain Reactome: R-HSA-8951664|Reactome: R-HSA-983168 AFULGI_00015270 7cd15dbf60812885c4bb52f3fde66207 2419 SUPERFAMILY SSF49265 311 411 9.51E-10 T 01-11-2018 IPR036116 Fibronectin type III superfamily GO:0005515 AFULGI_00015270 7cd15dbf60812885c4bb52f3fde66207 2419 Gene3D G3DSA:2.160.20.10 48 272 2.1E-19 T 01-11-2018 IPR012334 Pectin lyase fold AFULGI_00015270 7cd15dbf60812885c4bb52f3fde66207 2419 Gene3D G3DSA:2.160.20.10 415 768 3.1E-16 T 01-11-2018 IPR012334 Pectin lyase fold AFULGI_00015270 7cd15dbf60812885c4bb52f3fde66207 2419 SUPERFAMILY SSF51126 769 1042 6.28E-20 T 01-11-2018 IPR011050 Pectin lyase fold/virulence factor AFULGI_00005950 f169dabbed2f803c537f536f3f2c549f 485 Pfam PF13337 Putative ATP-dependent Lon protease 12 474 4.9E-151 T 01-11-2018 IPR014061 Conserved hypothetical protein CHP02688 AFULGI_00005950 f169dabbed2f803c537f536f3f2c549f 485 TIGRFAM TIGR02688 TIGR02688: TIGR02688 family protein 10 470 2.5E-146 T 01-11-2018 IPR014061 Conserved hypothetical protein CHP02688 AFULGI_00000670 ae52b5d7f05eee8fcca3b7004278f34a 66 SUPERFAMILY SSF143100 14 56 7.19E-6 T 01-11-2018 IPR035069 TTHA1013/TTHA0281-like AFULGI_00014340 1fa1a3a9b3faafbd30b81ae69fba0b56 457 Gene3D G3DSA:3.90.1150.10 6 392 1.2E-109 T 01-11-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFULGI_00014340 1fa1a3a9b3faafbd30b81ae69fba0b56 457 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 34 310 1.6E-18 T 01-11-2018 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 AFULGI_00014340 1fa1a3a9b3faafbd30b81ae69fba0b56 457 SUPERFAMILY SSF53383 5 401 1.1E-103 T 01-11-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFULGI_00014340 1fa1a3a9b3faafbd30b81ae69fba0b56 457 Gene3D G3DSA:3.40.640.10 44 300 1.2E-109 T 01-11-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFULGI_00006010 bb73208f651cd5ccc3322ea45ca62a73 199 Pfam PF11611 Domain of unknown function (DUF4352) 78 185 2.6E-6 T 01-11-2018 IPR029051 Domain of unknown function DUF4352 AFULGI_00006010 bb73208f651cd5ccc3322ea45ca62a73 199 Gene3D G3DSA:2.60.40.1240 66 195 6.6E-11 T 01-11-2018 IPR029050 Immunoprotective extracellular, immunoglobulin-like domain superfamily AFULGI_00013180 8cbce724195f37d0270fafe2bc350848 251 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 20 251 37.344 T 01-11-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 AFULGI_00013180 8cbce724195f37d0270fafe2bc350848 251 SUPERFAMILY SSF64005 18 246 5.1E-80 T 01-11-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 AFULGI_00013180 8cbce724195f37d0270fafe2bc350848 251 Gene3D G3DSA:3.40.1180.10 3 245 2.7E-92 T 01-11-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 AFULGI_00013180 8cbce724195f37d0270fafe2bc350848 251 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 20 247 9.2E-81 T 01-11-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 AFULGI_00013180 8cbce724195f37d0270fafe2bc350848 251 Pfam PF01255 Putative undecaprenyl diphosphate synthase 27 246 6.2E-78 T 01-11-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 AFULGI_00013180 8cbce724195f37d0270fafe2bc350848 251 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 196 213 - T 01-11-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199|Reactome: R-HSA-4755609 AFULGI_00010380 492daf40e007b0270f791574759ed7ec 144 Gene3D G3DSA:3.30.460.10 3 118 4.1E-10 T 01-11-2018 AFULGI_00010380 492daf40e007b0270f791574759ed7ec 144 SUPERFAMILY SSF81301 8 104 4.78E-16 T 01-11-2018 AFULGI_00010380 492daf40e007b0270f791574759ed7ec 144 Pfam PF01909 Nucleotidyltransferase domain 13 120 2.1E-8 T 01-11-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 AFULGI_00019770 65fb0535c832ae9597dd9e72cb2c5ec1 253 PIRSF PIRSF006493 1 253 3.0E-108 T 01-11-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type AFULGI_00019770 65fb0535c832ae9597dd9e72cb2c5ec1 253 SMART SM00559 52 180 6.3E-51 T 01-11-2018 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571|Reactome: R-HSA-6798695 AFULGI_00019770 65fb0535c832ae9597dd9e72cb2c5ec1 253 SUPERFAMILY SSF100939 1 252 5.3E-53 T 01-11-2018 IPR016194 SPOC-like, C-terminal domain superfamily AFULGI_00019770 65fb0535c832ae9597dd9e72cb2c5ec1 253 Hamap MF_01875 Non-homologous end joining protein Ku [ku]. 1 250 32.928 T 01-11-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type AFULGI_00019770 65fb0535c832ae9597dd9e72cb2c5ec1 253 Pfam PF02735 Ku70/Ku80 beta-barrel domain 11 190 7.6E-40 T 01-11-2018 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571|Reactome: R-HSA-6798695 AFULGI_00019770 65fb0535c832ae9597dd9e72cb2c5ec1 253 TIGRFAM TIGR02772 Ku_bact: Ku protein 1 252 8.7E-100 T 01-11-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type AFULGI_00019770 65fb0535c832ae9597dd9e72cb2c5ec1 253 Gene3D G3DSA:2.40.290.10 2 175 3.3E-24 T 01-11-2018 IPR016194 SPOC-like, C-terminal domain superfamily AFULGI_00021500 492eb4f934e669e22dc6ffa386afe74d 139 Pfam PF07650 KH domain 14 90 2.9E-16 T 01-11-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00021500 492eb4f934e669e22dc6ffa386afe74d 139 SUPERFAMILY SSF54814 72 135 5.3E-13 T 01-11-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 AFULGI_00021500 492eb4f934e669e22dc6ffa386afe74d 139 Hamap MF_00945_A Transcription termination/antitermination protein NusA [nusA]. 1 139 28.598 T 01-11-2018 IPR010212 Probable transcription termination protein NusA, archaeal AFULGI_00021500 492eb4f934e669e22dc6ffa386afe74d 139 SUPERFAMILY SSF54814 13 72 1.7E-11 T 01-11-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 AFULGI_00021500 492eb4f934e669e22dc6ffa386afe74d 139 TIGRFAM TIGR01952 nusA_arch: NusA family KH domain protein, archaeal 1 138 1.2E-61 T 01-11-2018 IPR010212 Probable transcription termination protein NusA, archaeal AFULGI_00021500 492eb4f934e669e22dc6ffa386afe74d 139 Gene3D G3DSA:3.30.300.20 72 139 5.4E-24 T 01-11-2018 IPR015946 K homology domain-like, alpha/beta AFULGI_00021500 492eb4f934e669e22dc6ffa386afe74d 139 Gene3D G3DSA:3.30.300.20 1 71 8.9E-25 T 01-11-2018 IPR015946 K homology domain-like, alpha/beta AFULGI_00021500 492eb4f934e669e22dc6ffa386afe74d 139 SMART SM00322 30 97 2.8E-4 T 01-11-2018 IPR004087 K Homology domain GO:0003676 AFULGI_00004610 2d95316dfc2ce4e0e1fd6a4ea2633531 632 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 2 330 9.8E-71 T 01-11-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 AFULGI_00004610 2d95316dfc2ce4e0e1fd6a4ea2633531 632 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 375 600 3.9E-34 T 01-11-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFULGI_00004610 2d95316dfc2ce4e0e1fd6a4ea2633531 632 Gene3D G3DSA:3.20.20.70 1 369 1.2E-126 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFULGI_00004610 2d95316dfc2ce4e0e1fd6a4ea2633531 632 SUPERFAMILY SSF51905 354 629 9.06E-50 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFULGI_00004610 2d95316dfc2ce4e0e1fd6a4ea2633531 632 SUPERFAMILY SSF51395 2 362 1.3E-107 T 01-11-2018 AFULGI_00004610 2d95316dfc2ce4e0e1fd6a4ea2633531 632 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 580 596 1.4E-18 T 01-11-2018 AFULGI_00004610 2d95316dfc2ce4e0e1fd6a4ea2633531 632 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 377 396 1.4E-18 T 01-11-2018 AFULGI_00004610 2d95316dfc2ce4e0e1fd6a4ea2633531 632 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 459 477 1.4E-18 T 01-11-2018 AFULGI_00004610 2d95316dfc2ce4e0e1fd6a4ea2633531 632 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 497 515 1.4E-18 T 01-11-2018 AFULGI_00004610 2d95316dfc2ce4e0e1fd6a4ea2633531 632 Gene3D G3DSA:3.40.50.720 376 626 1.3E-75 T 01-11-2018 AFULGI_00004610 2d95316dfc2ce4e0e1fd6a4ea2633531 632 Gene3D G3DSA:3.50.50.60 471 588 1.3E-75 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFULGI_00014280 161a1b93467713d8442f1b250b2fb0d5 426 Gene3D G3DSA:3.40.50.2300 1 171 2.3E-118 T 01-11-2018 AFULGI_00014280 161a1b93467713d8442f1b250b2fb0d5 426 Gene3D G3DSA:3.30.420.10 172 426 6.8E-69 T 01-11-2018 IPR036397 Ribonuclease H superfamily GO:0003676 AFULGI_00014280 161a1b93467713d8442f1b250b2fb0d5 426 SMART SM00950 109 405 1.7E-40 T 01-11-2018 IPR003165 Piwi domain GO:0003676 AFULGI_00014280 161a1b93467713d8442f1b250b2fb0d5 426 SUPERFAMILY SSF53098 3 426 8.09E-64 T 01-11-2018 IPR012337 Ribonuclease H-like superfamily AFULGI_00014280 161a1b93467713d8442f1b250b2fb0d5 426 Pfam PF02171 Piwi domain 110 404 1.0E-70 T 01-11-2018 IPR003165 Piwi domain GO:0003676 AFULGI_00008600 8ed20aefd44586f8b0c1f400e1bf28cc 312 Gene3D G3DSA:2.40.50.140 63 166 4.5E-28 T 01-11-2018 AFULGI_00008600 8ed20aefd44586f8b0c1f400e1bf28cc 312 SUPERFAMILY SSF50249 60 162 9.0E-27 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold AFULGI_00008600 8ed20aefd44586f8b0c1f400e1bf28cc 312 SUPERFAMILY SSF50249 146 281 1.15E-12 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold AFULGI_00008350 b3e9356213cf20bdf27a063a602daa4a 378 Gene3D G3DSA:1.10.10.10 130 235 3.3E-6 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00008350 b3e9356213cf20bdf27a063a602daa4a 378 SUPERFAMILY SSF46785 129 235 1.32E-8 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00016850 ac26dcea3ed614869d0b9346af9748dd 60 Gene3D G3DSA:4.10.1150.10 1 59 3.4E-18 T 01-11-2018 IPR024069 AF2212-like domain superfamily AFULGI_00016850 ac26dcea3ed614869d0b9346af9748dd 60 Pfam PF01954 Protein of unknown function DUF104 1 57 6.1E-21 T 01-11-2018 IPR008203 Uncharacterised protein family UPF0165 AFULGI_00016850 ac26dcea3ed614869d0b9346af9748dd 60 SUPERFAMILY SSF141694 1 58 3.14E-16 T 01-11-2018 AFULGI_00016040 a94e1fe34978851fab6d552f0343b544 79 SUPERFAMILY SSF143100 8 58 5.75E-13 T 01-11-2018 IPR035069 TTHA1013/TTHA0281-like AFULGI_00016040 a94e1fe34978851fab6d552f0343b544 79 Gene3D G3DSA:3.30.160.250 8 74 1.3E-10 T 01-11-2018 AFULGI_00004830 ca4e12aa373e8e9266e13f9b2f7e49ba 370 Gene3D G3DSA:1.20.1530.20 24 362 1.7E-22 T 01-11-2018 IPR038770 Sodium/solute symporter superfamily AFULGI_00004830 ca4e12aa373e8e9266e13f9b2f7e49ba 370 TIGRFAM TIGR00832 acr3: arsenical-resistance protein 30 360 5.8E-137 T 01-11-2018 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 AFULGI_00004830 ca4e12aa373e8e9266e13f9b2f7e49ba 370 PIRSF PIRSF005508 13 370 2.1E-133 T 01-11-2018 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 AFULGI_00004830 ca4e12aa373e8e9266e13f9b2f7e49ba 370 Pfam PF01758 Sodium Bile acid symporter family 75 272 1.7E-67 T 01-11-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 AFULGI_00026800 e9db66212efeb92632fa208d5a6fcfc3 343 Gene3D G3DSA:3.40.47.10 1 343 8.9E-82 T 01-11-2018 IPR016039 Thiolase-like GO:0003824 AFULGI_00026800 e9db66212efeb92632fa208d5a6fcfc3 343 SUPERFAMILY SSF53901 168 341 3.42E-49 T 01-11-2018 IPR016039 Thiolase-like GO:0003824 AFULGI_00026800 e9db66212efeb92632fa208d5a6fcfc3 343 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 217 305 2.0E-9 T 01-11-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 AFULGI_00026800 e9db66212efeb92632fa208d5a6fcfc3 343 Hamap MF_01409 UPF0219 protein . 1 343 63.037 T 01-11-2018 IPR004656 Putative condensing enzyme FabH-related AFULGI_00026800 e9db66212efeb92632fa208d5a6fcfc3 343 SUPERFAMILY SSF53901 2 167 5.76E-40 T 01-11-2018 IPR016039 Thiolase-like GO:0003824 AFULGI_00026800 e9db66212efeb92632fa208d5a6fcfc3 343 TIGRFAM TIGR00748 HMG_CoA_syn_Arc: putative hydroxymethylglutaryl-CoA synthase 1 342 7.9E-167 T 01-11-2018 IPR004656 Putative condensing enzyme FabH-related AFULGI_00005150 7ec09064835300dd961ec168659d3bbb 208 SUPERFAMILY SSF89550 2 182 6.67E-42 T 01-11-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 AFULGI_00005150 7ec09064835300dd961ec168659d3bbb 208 Pfam PF02811 PHP domain 5 74 1.9E-11 T 01-11-2018 IPR004013 PHP domain GO:0003824 AFULGI_00005150 7ec09064835300dd961ec168659d3bbb 208 SMART SM00481 4 71 1.3E-22 T 01-11-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal AFULGI_00005150 7ec09064835300dd961ec168659d3bbb 208 Gene3D G3DSA:3.20.20.140 1 198 4.8E-44 T 01-11-2018 AFULGI_00005150 7ec09064835300dd961ec168659d3bbb 208 Pfam PF13263 PHP-associated 136 181 7.7E-11 T 01-11-2018 AFULGI_00005560 aa0a4c769cbc138d014228efc3a9748c 231 SUPERFAMILY SSF103501 8 230 2.88E-27 T 01-11-2018 IPR036197 NarG-like superfamily AFULGI_00005560 aa0a4c769cbc138d014228efc3a9748c 231 Gene3D G3DSA:1.20.950.20 71 218 8.6E-15 T 01-11-2018 AFULGI_00005560 aa0a4c769cbc138d014228efc3a9748c 231 Pfam PF02665 Nitrate reductase gamma subunit 78 214 5.1E-11 T 01-11-2018 IPR023234 NarG-like domain AFULGI_00020070 36309f525ec9f7f73f8aee5b4005d222 113 SMART SM01078 3 110 4.7E-5 T 01-11-2018 IPR014925 Uncharacterised domain CGGC-dom AFULGI_00020070 36309f525ec9f7f73f8aee5b4005d222 113 Pfam PF08821 CGGC domain 4 110 4.3E-19 T 01-11-2018 IPR014925 Uncharacterised domain CGGC-dom AFULGI_00008760 0485e48ca8dfa0f28764ac3f112e522e 332 Gene3D G3DSA:1.20.58.220 135 232 1.5E-9 T 01-11-2018 IPR038078 PhoU-like domain superfamily AFULGI_00008760 0485e48ca8dfa0f28764ac3f112e522e 332 SUPERFAMILY SSF109755 126 309 1.03E-18 T 01-11-2018 AFULGI_00008760 0485e48ca8dfa0f28764ac3f112e522e 332 Pfam PF01895 PhoU domain 138 225 1.4E-11 T 01-11-2018 IPR026022 PhoU domain AFULGI_00008760 0485e48ca8dfa0f28764ac3f112e522e 332 SUPERFAMILY SSF89447 11 51 2.96E-5 T 01-11-2018 IPR037914 SpoVT-AbrB domain superfamily AFULGI_00008760 0485e48ca8dfa0f28764ac3f112e522e 332 SMART SM00966 8 53 5.5E-7 T 01-11-2018 IPR007159 SpoVT-AbrB domain GO:0003677 AFULGI_00008760 0485e48ca8dfa0f28764ac3f112e522e 332 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 10 49 5.7E-9 T 01-11-2018 IPR007159 SpoVT-AbrB domain GO:0003677 AFULGI_00022290 379ae80792b6144cb29b5c0e17c9b418 202 Gene3D G3DSA:3.30.1490.150 107 179 2.2E-71 T 01-11-2018 AFULGI_00022290 379ae80792b6144cb29b5c0e17c9b418 202 Gene3D G3DSA:3.30.700.20 5 191 2.2E-71 T 01-11-2018 IPR027485 AMMECR1, N-terminal AFULGI_00022290 379ae80792b6144cb29b5c0e17c9b418 202 Hamap MF_00645 Protein . 6 181 39.557 T 01-11-2018 IPR023472 Uncharacterised protein family MJ0810 AFULGI_00022290 379ae80792b6144cb29b5c0e17c9b418 202 TIGRFAM TIGR00296 TIGR00296: uncharacterized protein, PH0010 family 3 195 2.3E-92 T 01-11-2018 IPR023473 AMMECR1 AFULGI_00022290 379ae80792b6144cb29b5c0e17c9b418 202 TIGRFAM TIGR04335 AmmeMemoSam_A: AmmeMemoRadiSam system protein A 13 183 4.6E-57 T 01-11-2018 IPR027623 AmmeMemoRadiSam system protein A AFULGI_00022290 379ae80792b6144cb29b5c0e17c9b418 202 SUPERFAMILY SSF143447 3 196 1.7E-67 T 01-11-2018 IPR036071 AMMECR1 domain superfamily AFULGI_00022290 379ae80792b6144cb29b5c0e17c9b418 202 Pfam PF01871 AMMECR1 14 183 4.5E-52 T 01-11-2018 IPR002733 AMMECR1 domain AFULGI_00016840 10a5d587b16164aa8e1baeb57af97320 148 Gene3D G3DSA:3.40.50.1010 1 126 1.2E-9 T 01-11-2018 AFULGI_00016840 10a5d587b16164aa8e1baeb57af97320 148 Pfam PF01850 PIN domain 2 123 7.1E-13 T 01-11-2018 IPR002716 PIN domain AFULGI_00016840 10a5d587b16164aa8e1baeb57af97320 148 SUPERFAMILY SSF88723 1 124 1.99E-14 T 01-11-2018 IPR029060 PIN-like domain superfamily AFULGI_00018960 0ffdcf222e4cffc3b21d70d62a13692c 261 Pfam PF00288 GHMP kinases N terminal domain 68 126 7.5E-6 T 01-11-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 AFULGI_00018960 0ffdcf222e4cffc3b21d70d62a13692c 261 SUPERFAMILY SSF54211 2 130 6.45E-8 T 01-11-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFULGI_00018960 0ffdcf222e4cffc3b21d70d62a13692c 261 PIRSF PIRSF016896 1 261 1.2E-88 T 01-11-2018 IPR012043 Pantoate kinase KEGG: 00770+2.7.1.169|MetaCyc: PWY-6654 AFULGI_00014210 47fc60e0a7db731d4faa7796a02e15d6 287 Pfam PF04055 Radical SAM superfamily 21 176 1.5E-17 T 01-11-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFULGI_00014210 47fc60e0a7db731d4faa7796a02e15d6 287 SMART SM00729 15 232 2.1E-36 T 01-11-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 AFULGI_00014210 47fc60e0a7db731d4faa7796a02e15d6 287 Gene3D G3DSA:3.20.20.70 13 239 8.8E-22 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFULGI_00014210 47fc60e0a7db731d4faa7796a02e15d6 287 SUPERFAMILY SSF102114 3 239 2.62E-43 T 01-11-2018 AFULGI_00016920 4995b09fc2ceaf9a8b74a78bacc1422d 433 SMART SM00933 55 401 4.3E-20 T 01-11-2018 IPR018977 NurA domain AFULGI_00016920 4995b09fc2ceaf9a8b74a78bacc1422d 433 Pfam PF09376 NurA domain 56 351 6.0E-15 T 01-11-2018 IPR018977 NurA domain AFULGI_00020510 f59a53dd1782b2374e813c67b0e1eb5c 226 TIGRFAM TIGR00153 TIGR00153: TIGR00153 family protein 3 226 2.2E-93 T 01-11-2018 IPR002727 Protein of unknown function DUF47 AFULGI_00020510 f59a53dd1782b2374e813c67b0e1eb5c 226 Gene3D G3DSA:1.20.58.220 3 224 4.6E-52 T 01-11-2018 IPR038078 PhoU-like domain superfamily AFULGI_00020510 f59a53dd1782b2374e813c67b0e1eb5c 226 Pfam PF01865 Protein of unknown function DUF47 8 224 5.8E-84 T 01-11-2018 IPR018445 Putative phosphate transport regulator AFULGI_00020510 f59a53dd1782b2374e813c67b0e1eb5c 226 SUPERFAMILY SSF109755 23 208 3.31E-8 T 01-11-2018 AFULGI_00018850 57c588f931b79c95e87364a708f6e2ea 306 SUPERFAMILY SSF102114 6 233 3.14E-35 T 01-11-2018 AFULGI_00018850 57c588f931b79c95e87364a708f6e2ea 306 SMART SM00729 15 232 2.9E-28 T 01-11-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 AFULGI_00018850 57c588f931b79c95e87364a708f6e2ea 306 Gene3D G3DSA:3.20.20.70 16 235 1.5E-13 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFULGI_00018850 57c588f931b79c95e87364a708f6e2ea 306 Pfam PF04055 Radical SAM superfamily 22 176 2.8E-20 T 01-11-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFULGI_00026850 5992456f8d79938bf34098750ace89d7 547 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 70 189 2.2E-22 T 01-11-2018 IPR000014 PAS domain AFULGI_00026850 5992456f8d79938bf34098750ace89d7 547 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 186 310 1.0E-37 T 01-11-2018 IPR000014 PAS domain AFULGI_00026850 5992456f8d79938bf34098750ace89d7 547 Gene3D G3DSA:3.30.450.20 191 313 1.8E-31 T 01-11-2018 AFULGI_00026850 5992456f8d79938bf34098750ace89d7 547 Gene3D G3DSA:3.30.450.20 69 190 5.2E-18 T 01-11-2018 AFULGI_00026850 5992456f8d79938bf34098750ace89d7 547 Pfam PF00989 PAS fold 190 300 3.7E-16 T 01-11-2018 IPR013767 PAS fold GO:0006355 AFULGI_00026850 5992456f8d79938bf34098750ace89d7 547 Pfam PF00989 PAS fold 73 179 6.1E-10 T 01-11-2018 IPR013767 PAS fold GO:0006355 AFULGI_00026850 5992456f8d79938bf34098750ace89d7 547 SMART SM00388 474 530 0.0046 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFULGI_00026850 5992456f8d79938bf34098750ace89d7 547 Gene3D G3DSA:3.30.450.40 314 462 9.5E-16 T 01-11-2018 IPR029016 GAF-like domain superfamily AFULGI_00026850 5992456f8d79938bf34098750ace89d7 547 SUPERFAMILY SSF55785 186 301 4.54E-26 T 01-11-2018 IPR035965 PAS domain superfamily AFULGI_00026850 5992456f8d79938bf34098750ace89d7 547 Pfam PF13185 GAF domain 331 457 4.8E-14 T 01-11-2018 IPR003018 GAF domain GO:0005515 AFULGI_00026850 5992456f8d79938bf34098750ace89d7 547 SUPERFAMILY SSF55781 298 457 3.49E-17 T 01-11-2018 AFULGI_00026850 5992456f8d79938bf34098750ace89d7 547 SMART SM00065 332 466 0.0053 T 01-11-2018 IPR003018 GAF domain GO:0005515 AFULGI_00026850 5992456f8d79938bf34098750ace89d7 547 SUPERFAMILY SSF55785 75 183 3.91E-21 T 01-11-2018 IPR035965 PAS domain superfamily AFULGI_00026850 5992456f8d79938bf34098750ace89d7 547 SMART SM00091 72 137 1.0E-10 T 01-11-2018 IPR000014 PAS domain AFULGI_00026850 5992456f8d79938bf34098750ace89d7 547 SMART SM00091 189 255 2.4E-12 T 01-11-2018 IPR000014 PAS domain AFULGI_00013070 d35aa4eae36503b7f154b7da15bef4bf 114 Pfam PF07883 Cupin domain 40 108 6.6E-11 T 01-11-2018 IPR013096 Cupin 2, conserved barrel AFULGI_00013070 d35aa4eae36503b7f154b7da15bef4bf 114 SUPERFAMILY SSF51182 1 112 7.19E-21 T 01-11-2018 IPR011051 RmlC-like cupin domain superfamily AFULGI_00013070 d35aa4eae36503b7f154b7da15bef4bf 114 Gene3D G3DSA:2.60.120.10 1 114 2.6E-17 T 01-11-2018 IPR014710 RmlC-like jelly roll fold AFULGI_00019430 9845854d9a2574cc133d5219775007d9 420 Pfam PF00579 tRNA synthetases class I (W and Y) 61 226 4.3E-22 T 01-11-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFULGI_00019430 9845854d9a2574cc133d5219775007d9 420 Pfam PF00579 tRNA synthetases class I (W and Y) 281 402 1.3E-15 T 01-11-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFULGI_00019430 9845854d9a2574cc133d5219775007d9 420 Hamap MF_00140_A Tryptophan--tRNA ligase [trpS]. 2 419 47.912 T 01-11-2018 IPR020653 Tryptophan-tRNA ligase, archaea GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 AFULGI_00019430 9845854d9a2574cc133d5219775007d9 420 SUPERFAMILY SSF52374 2 411 7.03E-77 T 01-11-2018 AFULGI_00019430 9845854d9a2574cc133d5219775007d9 420 Gene3D G3DSA:1.10.240.10 309 419 4.5E-42 T 01-11-2018 AFULGI_00019430 9845854d9a2574cc133d5219775007d9 420 Gene3D G3DSA:3.40.50.620 1 233 5.9E-60 T 01-11-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFULGI_00019430 9845854d9a2574cc133d5219775007d9 420 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 127 146 1.9E-11 T 01-11-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 AFULGI_00019430 9845854d9a2574cc133d5219775007d9 420 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 308 318 1.9E-11 T 01-11-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 AFULGI_00019430 9845854d9a2574cc133d5219775007d9 420 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 203 224 1.9E-11 T 01-11-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 AFULGI_00019000 574e7c8c74a2d3d471f2c5417d42b5b2 399 Gene3D G3DSA:3.40.50.740 236 397 5.3E-7 T 01-11-2018 AFULGI_00019000 574e7c8c74a2d3d471f2c5417d42b5b2 399 Gene3D G3DSA:3.40.228.10 105 215 6.3E-7 T 01-11-2018 AFULGI_00019000 574e7c8c74a2d3d471f2c5417d42b5b2 399 PIRSF PIRSF005646 1 399 1.2E-149 T 01-11-2018 IPR016457 Formylmethanofuran dehydrogenase, subunit B GO:0015948|GO:0018493 KEGG: 00680+1.2.7.12|MetaCyc: PWY-5209|MetaCyc: PWY-7784 AFULGI_00019000 574e7c8c74a2d3d471f2c5417d42b5b2 399 SUPERFAMILY SSF53706 4 380 1.19E-30 T 01-11-2018 AFULGI_00019000 574e7c8c74a2d3d471f2c5417d42b5b2 399 TIGRFAM TIGR03129 one_C_dehyd_B: formylmethanofuran dehydrogenase subunit B 3 398 2.4E-140 T 01-11-2018 IPR016457 Formylmethanofuran dehydrogenase, subunit B GO:0015948|GO:0018493 KEGG: 00680+1.2.7.12|MetaCyc: PWY-5209|MetaCyc: PWY-7784 AFULGI_00026120 17c349e7489eda01fdc96563bda11e5e 163 SUPERFAMILY SSF47240 4 124 9.55E-35 T 01-11-2018 IPR009078 Ferritin-like superfamily AFULGI_00026120 17c349e7489eda01fdc96563bda11e5e 163 Pfam PF02915 Rubrerythrin 7 121 3.8E-25 T 01-11-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 AFULGI_00026120 17c349e7489eda01fdc96563bda11e5e 163 SUPERFAMILY SSF57802 131 162 9.97E-11 T 01-11-2018 AFULGI_00026120 17c349e7489eda01fdc96563bda11e5e 163 Gene3D G3DSA:2.20.28.10 129 163 4.3E-16 T 01-11-2018 AFULGI_00026120 17c349e7489eda01fdc96563bda11e5e 163 Gene3D G3DSA:1.20.1260.10 2 127 7.7E-42 T 01-11-2018 IPR012347 Ferritin-like AFULGI_00026250 f2d9e229ddcf5656a55506c5486b970b 97 Gene3D G3DSA:3.30.1860.10 1 97 1.4E-28 T 01-11-2018 AFULGI_00026250 f2d9e229ddcf5656a55506c5486b970b 97 Pfam PF04242 Protein of unknown function (DUF424) 7 97 7.0E-32 T 01-11-2018 IPR007355 Protein of unknown function DUF424 AFULGI_00018560 8ad71339e9632e4b34ca2513e92bf656 103 SUPERFAMILY SSF53850 35 102 2.75E-9 T 01-11-2018 AFULGI_00018560 8ad71339e9632e4b34ca2513e92bf656 103 Gene3D G3DSA:3.40.190.10 27 103 2.0E-15 T 01-11-2018 AFULGI_00025220 5a0cbd2a1e508265bb70343e51a55996 453 Hamap MF_00027 Hydrogenobyrinate a,c-diamide synthase [cobB]. 3 439 44.497 T 01-11-2018 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 AFULGI_00025220 5a0cbd2a1e508265bb70343e51a55996 453 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 6 183 7.0E-20 T 01-11-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain AFULGI_00025220 5a0cbd2a1e508265bb70343e51a55996 453 Gene3D G3DSA:3.40.50.880 244 453 3.1E-11 T 01-11-2018 IPR029062 Class I glutamine amidotransferase-like AFULGI_00025220 5a0cbd2a1e508265bb70343e51a55996 453 Gene3D G3DSA:3.40.50.300 43 194 4.3E-19 T 01-11-2018 AFULGI_00025220 5a0cbd2a1e508265bb70343e51a55996 453 TIGRFAM TIGR00379 cobB: cobyrinic acid a,c-diamide synthase 5 451 1.1E-226 T 01-11-2018 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 AFULGI_00025220 5a0cbd2a1e508265bb70343e51a55996 453 SUPERFAMILY SSF52317 246 447 7.37E-33 T 01-11-2018 IPR029062 Class I glutamine amidotransferase-like AFULGI_00025220 5a0cbd2a1e508265bb70343e51a55996 453 SUPERFAMILY SSF52540 1 196 1.31E-40 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00025220 5a0cbd2a1e508265bb70343e51a55996 453 Gene3D G3DSA:3.40.50.300 6 41 7.2E-7 T 01-11-2018 AFULGI_00025220 5a0cbd2a1e508265bb70343e51a55996 453 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 249 438 5.2E-44 T 01-11-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 AFULGI_00011080 4f0bdce4a8c1a0f302460c0b3ac4b239 312 TIGRFAM TIGR01210 TIGR01210: radical SAM enzyme, TIGR01210 family 9 311 2.4E-144 T 01-11-2018 IPR005909 Conserved hypothetical protein CHP01210 AFULGI_00011080 4f0bdce4a8c1a0f302460c0b3ac4b239 312 SUPERFAMILY SSF102114 24 242 3.01E-18 T 01-11-2018 AFULGI_00011080 4f0bdce4a8c1a0f302460c0b3ac4b239 312 SMART SM00729 23 239 3.9E-38 T 01-11-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 AFULGI_00011080 4f0bdce4a8c1a0f302460c0b3ac4b239 312 PIRSF PIRSF004954 1 311 4.1E-132 T 01-11-2018 IPR005909 Conserved hypothetical protein CHP01210 AFULGI_00011080 4f0bdce4a8c1a0f302460c0b3ac4b239 312 Pfam PF04055 Radical SAM superfamily 29 184 3.5E-10 T 01-11-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFULGI_00012990 2b0dec22c7bca2641288d36c2530f6e3 290 SUPERFAMILY SSF102198 38 287 5.36E-53 T 01-11-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 AFULGI_00012990 2b0dec22c7bca2641288d36c2530f6e3 290 Pfam PF04199 Putative cyclase 41 192 1.1E-33 T 01-11-2018 IPR007325 Kynurenine formamidase/cyclase-like GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 AFULGI_00012990 2b0dec22c7bca2641288d36c2530f6e3 290 Gene3D G3DSA:3.50.30.50 22 289 1.1E-44 T 01-11-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 AFULGI_00002200 212241155f4be1faea95c926b0d6bc43 335 Gene3D G3DSA:3.30.2010.10 96 185 1.6E-18 T 01-11-2018 AFULGI_00002200 212241155f4be1faea95c926b0d6bc43 335 Hamap MF_00188 Protease HtpX [htpX]. 41 332 26.16 T 01-11-2018 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 AFULGI_00002200 212241155f4be1faea95c926b0d6bc43 335 Pfam PF01435 Peptidase family M48 103 332 2.5E-55 T 01-11-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 AFULGI_00016540 61b502aec8184991c471dc9ea4a60b05 154 SUPERFAMILY SSF88723 1 115 8.97E-11 T 01-11-2018 IPR029060 PIN-like domain superfamily AFULGI_00016540 61b502aec8184991c471dc9ea4a60b05 154 Pfam PF11848 Domain of unknown function (DUF3368) 110 153 2.8E-7 T 01-11-2018 IPR021799 Protein of unknown function DUF3368 AFULGI_00026230 0722d171caaa6d36cfba4d104ffc27c9 231 TIGRFAM TIGR00317 cobS: cobalamin 5'-phosphate synthase 1 225 2.7E-85 T 01-11-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 AFULGI_00026230 0722d171caaa6d36cfba4d104ffc27c9 231 Hamap MF_00719 Adenosylcobinamide-GDP ribazoletransferase [cobS]. 1 231 23.684 T 01-11-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 AFULGI_00026230 0722d171caaa6d36cfba4d104ffc27c9 231 Pfam PF02654 Cobalamin-5-phosphate synthase 8 222 1.1E-35 T 01-11-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 AFULGI_00022130 f3922e8737314a3f86f4efb83bec7b74 453 SUPERFAMILY SSF75304 4 443 2.75E-136 T 01-11-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AFULGI_00022130 f3922e8737314a3f86f4efb83bec7b74 453 Gene3D G3DSA:3.90.1300.10 1 452 1.2E-145 T 01-11-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AFULGI_00022130 f3922e8737314a3f86f4efb83bec7b74 453 Pfam PF01425 Amidase 20 434 3.9E-132 T 01-11-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AFULGI_00022130 f3922e8737314a3f86f4efb83bec7b74 453 ProSitePatterns PS00571 Amidases signature. 140 171 - T 01-11-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 AFULGI_00013820 deff0afc9c584452e540efd623f9d934 1076 SUPERFAMILY SSF52440 558 677 1.34E-51 T 01-11-2018 IPR016185 Pre-ATP-grasp domain superfamily AFULGI_00013820 deff0afc9c584452e540efd623f9d934 1076 Gene3D G3DSA:3.30.470.20 668 937 6.9E-121 T 01-11-2018 AFULGI_00013820 deff0afc9c584452e540efd623f9d934 1076 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 425 549 3.3E-44 T 01-11-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFULGI_00013820 deff0afc9c584452e540efd623f9d934 1076 SMART SM00851 958 1044 5.7E-29 T 01-11-2018 IPR011607 Methylglyoxal synthase-like domain AFULGI_00013820 deff0afc9c584452e540efd623f9d934 1076 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 840 847 - T 01-11-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AFULGI_00013820 deff0afc9c584452e540efd623f9d934 1076 Gene3D G3DSA:3.30.470.20 120 402 8.7E-129 T 01-11-2018 AFULGI_00013820 deff0afc9c584452e540efd623f9d934 1076 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 164 178 - T 01-11-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AFULGI_00013820 deff0afc9c584452e540efd623f9d934 1076 SUPERFAMILY SSF52335 937 1074 3.79E-36 T 01-11-2018 IPR036914 Methylglyoxal synthase-like domain superfamily AFULGI_00013820 deff0afc9c584452e540efd623f9d934 1076 SUPERFAMILY SSF56059 128 400 1.4E-111 T 01-11-2018 AFULGI_00013820 deff0afc9c584452e540efd623f9d934 1076 SUPERFAMILY SSF48108 395 555 2.35E-52 T 01-11-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFULGI_00013820 deff0afc9c584452e540efd623f9d934 1076 SUPERFAMILY SSF56059 675 935 3.54E-109 T 01-11-2018 AFULGI_00013820 deff0afc9c584452e540efd623f9d934 1076 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 1055 0.0 T 01-11-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFULGI_00013820 deff0afc9c584452e540efd623f9d934 1076 SMART SM01096 422 549 5.6E-70 T 01-11-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFULGI_00013820 deff0afc9c584452e540efd623f9d934 1076 Gene3D G3DSA:3.40.50.20 1 116 4.0E-50 T 01-11-2018 AFULGI_00013820 deff0afc9c584452e540efd623f9d934 1076 Hamap MF_01210_A Carbamoyl-phosphate synthase large chain [carB]. 5 1072 14.993 T 01-11-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFULGI_00013820 deff0afc9c584452e540efd623f9d934 1076 Gene3D G3DSA:3.40.50.1380 938 1076 2.9E-43 T 01-11-2018 IPR036914 Methylglyoxal synthase-like domain superfamily AFULGI_00013820 deff0afc9c584452e540efd623f9d934 1076 SUPERFAMILY SSF52440 1 127 2.45E-50 T 01-11-2018 IPR016185 Pre-ATP-grasp domain superfamily AFULGI_00013820 deff0afc9c584452e540efd623f9d934 1076 Gene3D G3DSA:3.40.50.20 556 664 5.4E-51 T 01-11-2018 AFULGI_00013820 deff0afc9c584452e540efd623f9d934 1076 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 711 725 - T 01-11-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AFULGI_00013820 deff0afc9c584452e540efd623f9d934 1076 Gene3D G3DSA:1.10.1030.10 407 555 8.9E-52 T 01-11-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFULGI_00013820 deff0afc9c584452e540efd623f9d934 1076 Pfam PF02142 MGS-like domain 959 1044 4.2E-20 T 01-11-2018 IPR011607 Methylglyoxal synthase-like domain AFULGI_00013820 deff0afc9c584452e540efd623f9d934 1076 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 675 877 2.6E-39 T 01-11-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AFULGI_00013820 deff0afc9c584452e540efd623f9d934 1076 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 334 2.2E-73 T 01-11-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AFULGI_00013820 deff0afc9c584452e540efd623f9d934 1076 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 8.7E-67 T 01-11-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFULGI_00013820 deff0afc9c584452e540efd623f9d934 1076 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 297 326 8.7E-67 T 01-11-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFULGI_00013820 deff0afc9c584452e540efd623f9d934 1076 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 8.7E-67 T 01-11-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFULGI_00013820 deff0afc9c584452e540efd623f9d934 1076 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 8.7E-67 T 01-11-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFULGI_00013820 deff0afc9c584452e540efd623f9d934 1076 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 8.7E-67 T 01-11-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFULGI_00013820 deff0afc9c584452e540efd623f9d934 1076 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 8.7E-67 T 01-11-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFULGI_00013820 deff0afc9c584452e540efd623f9d934 1076 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 379 397 8.7E-67 T 01-11-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFULGI_00013820 deff0afc9c584452e540efd623f9d934 1076 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1065 13.434 T 01-11-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFULGI_00003780 091d249d3003f179d12b530b804657ac 258 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 3 230 5.1E-24 T 01-11-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain AFULGI_00003780 091d249d3003f179d12b530b804657ac 258 PIRSF PIRSF005647 2 255 5.7E-85 T 01-11-2018 IPR014433 Nickel insertion ATPase/GTPase (CO dehydrogenase maturation factor), CooC type AFULGI_00003780 091d249d3003f179d12b530b804657ac 258 SUPERFAMILY SSF52540 1 252 9.9E-41 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00003780 091d249d3003f179d12b530b804657ac 258 Gene3D G3DSA:3.40.50.300 2 252 1.4E-56 T 01-11-2018 AFULGI_00001060 1c9cfce9d4f44e63303e4995e5e550a9 107 PIRSF PIRSF004878 2 107 6.7E-35 T 01-11-2018 IPR016432 Ribonuclease P, protein component 4 GO:0001682|GO:0004526 AFULGI_00001060 1c9cfce9d4f44e63303e4995e5e550a9 107 Hamap MF_00757 Ribonuclease P protein component 4 [rnp4]. 5 100 23.372 T 01-11-2018 IPR016432 Ribonuclease P, protein component 4 GO:0001682|GO:0004526 AFULGI_00001060 1c9cfce9d4f44e63303e4995e5e550a9 107 Gene3D G3DSA:1.20.5.420 2 58 2.4E-17 T 01-11-2018 AFULGI_00001060 1c9cfce9d4f44e63303e4995e5e550a9 107 Gene3D G3DSA:2.20.25.200 59 107 1.6E-7 T 01-11-2018 AFULGI_00001060 1c9cfce9d4f44e63303e4995e5e550a9 107 Pfam PF04032 RNAse P Rpr2/Rpp21/SNM1 subunit domain 19 91 5.0E-9 T 01-11-2018 IPR007175 RNAse P, Rpr2/Rpp21 subunit Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 AFULGI_00023740 a0ac312b71c866c661604399f77be3b2 233 Hamap MF_01285 Riboflavin kinase [ribK]. 105 231 27.797 T 01-11-2018 IPR023470 Riboflavin kinase, archaeal GO:0008531|GO:0009231 KEGG: 00740+2.7.1.161|MetaCyc: PWY-6167 AFULGI_00023740 a0ac312b71c866c661604399f77be3b2 233 SMART SM00419 30 82 6.2E-9 T 01-11-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 AFULGI_00023740 a0ac312b71c866c661604399f77be3b2 233 Gene3D G3DSA:2.40.30.30 102 233 6.0E-54 T 01-11-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 AFULGI_00023740 a0ac312b71c866c661604399f77be3b2 233 Gene3D G3DSA:1.10.10.10 17 100 3.9E-20 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00023740 a0ac312b71c866c661604399f77be3b2 233 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 36 52 5.6E-5 T 01-11-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 AFULGI_00023740 a0ac312b71c866c661604399f77be3b2 233 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 52 67 5.6E-5 T 01-11-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 AFULGI_00023740 a0ac312b71c866c661604399f77be3b2 233 Pfam PF13412 Winged helix-turn-helix DNA-binding 38 67 7.6E-7 T 01-11-2018 AFULGI_00023740 a0ac312b71c866c661604399f77be3b2 233 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 37 48 5.6E-5 T 01-11-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFULGI_00023740 a0ac312b71c866c661604399f77be3b2 233 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 48 67 5.6E-5 T 01-11-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFULGI_00023740 a0ac312b71c866c661604399f77be3b2 233 SUPERFAMILY SSF82114 104 231 2.06E-49 T 01-11-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 AFULGI_00023740 a0ac312b71c866c661604399f77be3b2 233 SUPERFAMILY SSF46785 23 95 1.49E-11 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00023740 a0ac312b71c866c661604399f77be3b2 233 Pfam PF01982 Domain of unknown function DUF120 111 231 7.3E-49 T 01-11-2018 IPR023602 Riboflavin kinase domain, CTP-dependent GO:0016773 KEGG: 00740+2.7.1.161|MetaCyc: PWY-6167 AFULGI_00001410 c4d3413f39c55ce6c1a73b7623b11260 126 SUPERFAMILY SSF49503 11 126 3.38E-25 T 01-11-2018 IPR008972 Cupredoxin AFULGI_00001410 c4d3413f39c55ce6c1a73b7623b11260 126 Gene3D G3DSA:2.60.40.420 22 125 4.4E-25 T 01-11-2018 IPR008972 Cupredoxin AFULGI_00001410 c4d3413f39c55ce6c1a73b7623b11260 126 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 71 119 - T 01-11-2018 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFULGI_00001410 c4d3413f39c55ce6c1a73b7623b11260 126 Pfam PF13473 Cupredoxin-like domain 8 125 1.8E-13 T 01-11-2018 IPR028096 EfeO-type cupredoxin-like domain AFULGI_00016970 6c7dc22c4c09fcc554e89c86e186cbd6 339 SUPERFAMILY SSF52788 189 333 7.85E-9 T 01-11-2018 IPR036196 Phosphotyrosine protein phosphatase I superfamily AFULGI_00016970 6c7dc22c4c09fcc554e89c86e186cbd6 339 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 193 327 6.5E-6 T 01-11-2018 IPR023485 Phosphotyrosine protein phosphatase I AFULGI_00016970 6c7dc22c4c09fcc554e89c86e186cbd6 339 Gene3D G3DSA:3.40.50.2300 188 336 3.8E-14 T 01-11-2018 AFULGI_00020350 7b4d300ad2a989196ac461391be719f6 177 TIGRFAM TIGR00537 hemK_rel_arch: putative methylase 2 175 9.3E-82 T 01-11-2018 IPR004557 Eukaryotic/archaeal PrmC-related GO:0008276 Reactome: R-HSA-156581|Reactome: R-HSA-72764 AFULGI_00020350 7b4d300ad2a989196ac461391be719f6 177 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 83 89 - T 01-11-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 AFULGI_00020350 7b4d300ad2a989196ac461391be719f6 177 SUPERFAMILY SSF53335 5 166 3.16E-20 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFULGI_00020350 7b4d300ad2a989196ac461391be719f6 177 Gene3D G3DSA:3.40.50.150 1 177 1.3E-32 T 01-11-2018 AFULGI_00020000 430a7660db6caf4f2b3e082c6b3fd3b6 388 Gene3D G3DSA:1.10.3430.10 1 388 6.4E-151 T 01-11-2018 IPR029020 Ammonium/urea transporter AFULGI_00020000 430a7660db6caf4f2b3e082c6b3fd3b6 388 Pfam PF00909 Ammonium Transporter Family 8 387 9.5E-135 T 01-11-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 AFULGI_00020000 430a7660db6caf4f2b3e082c6b3fd3b6 388 ProSitePatterns PS01219 Ammonium transporters signature. 149 174 - T 01-11-2018 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 AFULGI_00020000 430a7660db6caf4f2b3e082c6b3fd3b6 388 TIGRFAM TIGR00836 amt: ammonium transporter 5 387 1.2E-141 T 01-11-2018 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 AFULGI_00020000 430a7660db6caf4f2b3e082c6b3fd3b6 388 SUPERFAMILY SSF111352 2 368 5.49E-119 T 01-11-2018 AFULGI_00006490 87c226f6c1460b83b06453f840a2304b 53 Pfam PF07754 Domain of unknown function (DUF1610) 6 28 4.3E-11 T 01-11-2018 IPR011668 Domain of unknown function DUF1610 AFULGI_00007500 647f57cc2647135720999b60695b92a2 360 ProSitePatterns PS00789 Chorismate synthase signature 3. 324 340 - T 01-11-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 AFULGI_00007500 647f57cc2647135720999b60695b92a2 360 Pfam PF01264 Chorismate synthase 8 350 3.2E-146 T 01-11-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 AFULGI_00007500 647f57cc2647135720999b60695b92a2 360 PIRSF PIRSF001456 1 358 1.5E-154 T 01-11-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 AFULGI_00007500 647f57cc2647135720999b60695b92a2 360 Gene3D G3DSA:3.60.150.10 1 359 1.0E-152 T 01-11-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 AFULGI_00007500 647f57cc2647135720999b60695b92a2 360 ProSitePatterns PS00788 Chorismate synthase signature 2. 121 137 - T 01-11-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 AFULGI_00007500 647f57cc2647135720999b60695b92a2 360 SUPERFAMILY SSF103263 1 353 5.76E-143 T 01-11-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 AFULGI_00007500 647f57cc2647135720999b60695b92a2 360 TIGRFAM TIGR00033 aroC: chorismate synthase 8 352 3.0E-147 T 01-11-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 AFULGI_00007500 647f57cc2647135720999b60695b92a2 360 Hamap MF_00300 Chorismate synthase [aroC]. 8 357 39.328 T 01-11-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 AFULGI_00007500 647f57cc2647135720999b60695b92a2 360 ProSitePatterns PS00787 Chorismate synthase signature 1. 14 29 - T 01-11-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 AFULGI_00007960 af2aca93f3a3d00b24082557ecfa8c21 273 Hamap MF_00058 F420-dependent methylenetetrahydromethanopterin dehydrogenase [mtd]. 1 273 50.96 T 01-11-2018 IPR002844 F420-dependent methylenetetrahydromethanopterin dehydrogenase GO:0008901|GO:0015948|GO:0055114 KEGG: 00680+1.5.98.1|MetaCyc: PWY-5198 AFULGI_00007960 af2aca93f3a3d00b24082557ecfa8c21 273 ProDom PD017604 DEHYDROGENASE METHYLENETETRAHYDROMETHANOPTERIN F420-DEPENDENT MTD COENZYME DEPENDENT F420 N5N10- ONE-CARBON METABOLISM 9 273 3.0E-139 T 01-11-2018 IPR002844 F420-dependent methylenetetrahydromethanopterin dehydrogenase GO:0008901|GO:0015948|GO:0055114 KEGG: 00680+1.5.98.1|MetaCyc: PWY-5198 AFULGI_00007960 af2aca93f3a3d00b24082557ecfa8c21 273 PIRSF PIRSF005627 1 273 1.5E-143 T 01-11-2018 IPR002844 F420-dependent methylenetetrahydromethanopterin dehydrogenase GO:0008901|GO:0015948|GO:0055114 KEGG: 00680+1.5.98.1|MetaCyc: PWY-5198 AFULGI_00007960 af2aca93f3a3d00b24082557ecfa8c21 273 Pfam PF01993 methylene-5,6,7,8-tetrahydromethanopterin dehydrogenase 3 273 9.6E-136 T 01-11-2018 IPR002844 F420-dependent methylenetetrahydromethanopterin dehydrogenase GO:0008901|GO:0015948|GO:0055114 KEGG: 00680+1.5.98.1|MetaCyc: PWY-5198 AFULGI_00007960 af2aca93f3a3d00b24082557ecfa8c21 273 SUPERFAMILY SSF102324 1 273 1.05E-126 T 01-11-2018 IPR036080 F420-dependent methylenetetrahydromethanopterin dehydrogenase superfamily GO:0008901|GO:0015948|GO:0055114 KEGG: 00680+1.5.98.1|MetaCyc: PWY-5198 AFULGI_00007960 af2aca93f3a3d00b24082557ecfa8c21 273 Gene3D G3DSA:3.40.50.10830 1 131 2.3E-46 T 01-11-2018 AFULGI_00012380 61e47c3b731977e5f3381f44928230dc 247 SMART SM00382 25 207 1.6E-13 T 01-11-2018 IPR003593 AAA+ ATPase domain AFULGI_00012380 61e47c3b731977e5f3381f44928230dc 247 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFULGI_00012380 61e47c3b731977e5f3381f44928230dc 247 SUPERFAMILY SSF52540 2 223 3.03E-58 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00012380 61e47c3b731977e5f3381f44928230dc 247 Pfam PF00005 ABC transporter 23 159 5.5E-25 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFULGI_00012380 61e47c3b731977e5f3381f44928230dc 247 Gene3D G3DSA:3.40.50.300 1 237 1.8E-64 T 01-11-2018 AFULGI_00026220 c1e571b38b69cccbc2cf8668ef7819aa 219 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 7 209 3.8E-78 T 01-11-2018 AFULGI_00026220 c1e571b38b69cccbc2cf8668ef7819aa 219 SUPERFAMILY SSF53335 6 208 8.36E-50 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFULGI_00026220 c1e571b38b69cccbc2cf8668ef7819aa 219 TIGRFAM TIGR00080 pimt: protein-L-isoaspartate O-methyltransferase 4 210 2.8E-79 T 01-11-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 AFULGI_00026220 c1e571b38b69cccbc2cf8668ef7819aa 219 Hamap MF_00090 Protein-L-isoaspartate O-methyltransferase [pcm]. 4 213 42.978 T 01-11-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 AFULGI_00026220 c1e571b38b69cccbc2cf8668ef7819aa 219 ProSitePatterns PS01279 Protein-L-isoaspartate(D-aspartate) O-methyltransferase signature. 134 149 - T 01-11-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 AFULGI_00026220 c1e571b38b69cccbc2cf8668ef7819aa 219 Gene3D G3DSA:3.40.50.150 1 219 9.0E-89 T 01-11-2018 AFULGI_00015790 05235d8c00c5c577854628c94211b829 74 SMART SM00651 5 71 5.1E-24 T 01-11-2018 IPR001163 LSM domain, eukaryotic/archaea-type AFULGI_00015790 05235d8c00c5c577854628c94211b829 74 PIRSF PIRSF006609 1 74 5.6E-24 T 01-11-2018 IPR016487 Sm-like protein Lsm6/SmF GO:0000398|GO:0005732 Reactome: R-HSA-72163 AFULGI_00015790 05235d8c00c5c577854628c94211b829 74 SUPERFAMILY SSF50182 1 73 1.54E-20 T 01-11-2018 IPR010920 LSM domain superfamily AFULGI_00015790 05235d8c00c5c577854628c94211b829 74 Gene3D G3DSA:2.30.30.100 1 74 1.2E-25 T 01-11-2018 AFULGI_00015790 05235d8c00c5c577854628c94211b829 74 Pfam PF01423 LSM domain 7 71 7.9E-22 T 01-11-2018 IPR001163 LSM domain, eukaryotic/archaea-type AFULGI_00021730 83748e127393950fcb5e2c4fb5e10420 120 Pfam PF00467 KOW motif 50 81 4.8E-9 T 01-11-2018 IPR005824 KOW AFULGI_00021730 83748e127393950fcb5e2c4fb5e10420 120 Gene3D G3DSA:2.30.30.30 2 120 3.4E-45 T 01-11-2018 IPR014722 Ribosomal protein L2, domain 2 AFULGI_00021730 83748e127393950fcb5e2c4fb5e10420 120 Hamap MF_01326_A 50S ribosomal protein L24 [rplX]. 6 120 30.415 T 01-11-2018 IPR005756 Ribosomal protein L26/L24, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00021730 83748e127393950fcb5e2c4fb5e10420 120 SMART SM00739 47 74 1.2E-6 T 01-11-2018 IPR005824 KOW AFULGI_00021730 83748e127393950fcb5e2c4fb5e10420 120 Pfam PF16906 Ribosomal proteins L26 eukaryotic, L24P archaeal 6 120 2.3E-29 T 01-11-2018 IPR005756 Ribosomal protein L26/L24, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00021730 83748e127393950fcb5e2c4fb5e10420 120 ProSitePatterns PS01108 Ribosomal protein L24 signature. 51 68 - T 01-11-2018 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFULGI_00021730 83748e127393950fcb5e2c4fb5e10420 120 TIGRFAM TIGR01080 rplX_A_E: ribosomal protein uL24 6 120 9.7E-57 T 01-11-2018 IPR005756 Ribosomal protein L26/L24, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00021730 83748e127393950fcb5e2c4fb5e10420 120 SUPERFAMILY SSF50104 7 109 1.5E-31 T 01-11-2018 IPR008991 Translation protein SH3-like domain superfamily AFULGI_00020730 0ae2a699af7bb9029bda464c51327a71 231 Pfam PF00005 ABC transporter 21 164 1.6E-35 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFULGI_00020730 0ae2a699af7bb9029bda464c51327a71 231 Gene3D G3DSA:3.40.50.300 1 226 3.5E-68 T 01-11-2018 AFULGI_00020730 0ae2a699af7bb9029bda464c51327a71 231 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFULGI_00020730 0ae2a699af7bb9029bda464c51327a71 231 SUPERFAMILY SSF52540 1 218 1.49E-72 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00020730 0ae2a699af7bb9029bda464c51327a71 231 SMART SM00382 30 213 7.0E-16 T 01-11-2018 IPR003593 AAA+ ATPase domain AFULGI_00025820 b37e25e1339866389dfd0f978f7fdba9 172 Gene3D G3DSA:3.10.290.10 108 170 4.7E-18 T 01-11-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 AFULGI_00025820 b37e25e1339866389dfd0f978f7fdba9 172 Pfam PF01479 S4 domain 109 153 5.7E-17 T 01-11-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00025820 b37e25e1339866389dfd0f978f7fdba9 172 SMART SM00363 109 171 4.3E-12 T 01-11-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00025820 b37e25e1339866389dfd0f978f7fdba9 172 Hamap MF_01306_A 30S ribosomal protein S4 [rpsD]. 1 162 35.211 T 01-11-2018 IPR022802 Ribosomal protein S4, archaeal GO:0006412|GO:0019843 AFULGI_00025820 b37e25e1339866389dfd0f978f7fdba9 172 TIGRFAM TIGR01018 uS4_arch: ribosomal protein uS4 1 166 3.5E-79 T 01-11-2018 IPR005710 Ribosomal protein S4/S9, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00025820 b37e25e1339866389dfd0f978f7fdba9 172 SUPERFAMILY SSF55174 9 166 5.89E-33 T 01-11-2018 AFULGI_00025820 b37e25e1339866389dfd0f978f7fdba9 172 ProSitePatterns PS00632 Ribosomal protein S4 signature. 107 131 - T 01-11-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00025820 b37e25e1339866389dfd0f978f7fdba9 172 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 4 60 1.6E-6 T 01-11-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 AFULGI_00025820 b37e25e1339866389dfd0f978f7fdba9 172 SMART SM01390 5 108 4.1E-13 T 01-11-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 AFULGI_00017420 7235885408a65742db6a2a00286a99b4 215 ProSitePatterns PS01199 Ribosomal protein L1 signature. 115 134 - T 01-11-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00017420 7235885408a65742db6a2a00286a99b4 215 Gene3D G3DSA:3.30.190.20 19 210 9.2E-72 T 01-11-2018 AFULGI_00017420 7235885408a65742db6a2a00286a99b4 215 Gene3D G3DSA:3.40.50.790 60 150 9.2E-72 T 01-11-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich AFULGI_00017420 7235885408a65742db6a2a00286a99b4 215 Hamap MF_01318_A 50S ribosomal protein L1 [rplA]. 4 215 38.313 T 01-11-2018 IPR023669 Ribosomal protein L1, archaea GO:0003723|GO:0003735|GO:0006412|GO:0015934 AFULGI_00017420 7235885408a65742db6a2a00286a99b4 215 Pfam PF00687 Ribosomal protein L1p/L10e family 19 210 1.7E-43 T 01-11-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein AFULGI_00017420 7235885408a65742db6a2a00286a99b4 215 PIRSF PIRSF002155 1 215 2.8E-71 T 01-11-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00017420 7235885408a65742db6a2a00286a99b4 215 SUPERFAMILY SSF56808 5 214 1.57E-60 T 01-11-2018 IPR023674 Ribosomal protein L1-like AFULGI_00006390 b131992e65a216dab19a39a3668ec5ef 145 SUPERFAMILY SSF88723 3 121 6.17E-15 T 01-11-2018 IPR029060 PIN-like domain superfamily AFULGI_00006390 b131992e65a216dab19a39a3668ec5ef 145 Pfam PF01850 PIN domain 5 120 4.9E-15 T 01-11-2018 IPR002716 PIN domain AFULGI_00006390 b131992e65a216dab19a39a3668ec5ef 145 Gene3D G3DSA:3.40.50.1010 3 122 2.6E-11 T 01-11-2018 AFULGI_00019350 9e830f9accad59043d98fba6e75eb950 100 Pfam PF01909 Nucleotidyltransferase domain 7 98 4.1E-16 T 01-11-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 AFULGI_00019350 9e830f9accad59043d98fba6e75eb950 100 Gene3D G3DSA:3.30.460.10 1 98 2.7E-21 T 01-11-2018 AFULGI_00019350 9e830f9accad59043d98fba6e75eb950 100 SUPERFAMILY SSF81301 1 96 2.97E-22 T 01-11-2018 AFULGI_00013100 d5aa26840e490a840b5f9cfda18119b0 685 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 148 284 8.2E-59 T 01-11-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain AFULGI_00013100 d5aa26840e490a840b5f9cfda18119b0 685 SUPERFAMILY SSF52210 291 437 2.49E-35 T 01-11-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AFULGI_00013100 d5aa26840e490a840b5f9cfda18119b0 685 SUPERFAMILY SSF52210 126 290 2.35E-48 T 01-11-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AFULGI_00013100 d5aa26840e490a840b5f9cfda18119b0 685 Pfam PF13549 ATP-grasp domain 473 681 9.4E-77 T 01-11-2018 AFULGI_00013100 d5aa26840e490a840b5f9cfda18119b0 685 TIGRFAM TIGR02717 AcCoA-syn-alpha: acetyl coenzyme A synthetase (ADP forming), alpha domain 1 435 1.9E-191 T 01-11-2018 IPR014089 Acetate-CoA ligase [ADP-forming], alpha domain KEGG: 00010+6.2.1.13|KEGG: 00620+6.2.1.13|KEGG: 00640+6.2.1.13|MetaCyc: PWY-5483|MetaCyc: PWY-5535 AFULGI_00013100 d5aa26840e490a840b5f9cfda18119b0 685 Gene3D G3DSA:3.40.50.261 289 445 9.0E-43 T 01-11-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AFULGI_00013100 d5aa26840e490a840b5f9cfda18119b0 685 Gene3D G3DSA:3.40.50.720 1 126 8.3E-46 T 01-11-2018 AFULGI_00013100 d5aa26840e490a840b5f9cfda18119b0 685 SUPERFAMILY SSF51735 2 127 5.7E-41 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily AFULGI_00013100 d5aa26840e490a840b5f9cfda18119b0 685 Gene3D G3DSA:3.40.50.261 127 288 4.7E-66 T 01-11-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AFULGI_00013100 d5aa26840e490a840b5f9cfda18119b0 685 Pfam PF13380 CoA binding domain 8 132 2.1E-27 T 01-11-2018 IPR003781 CoA-binding GO:0048037 AFULGI_00013100 d5aa26840e490a840b5f9cfda18119b0 685 Gene3D G3DSA:3.30.1490.20 489 565 4.9E-83 T 01-11-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 AFULGI_00013100 d5aa26840e490a840b5f9cfda18119b0 685 Gene3D G3DSA:3.30.470.20 474 678 4.9E-83 T 01-11-2018 AFULGI_00013100 d5aa26840e490a840b5f9cfda18119b0 685 SMART SM00881 4 97 3.1E-41 T 01-11-2018 IPR003781 CoA-binding GO:0048037 AFULGI_00013100 d5aa26840e490a840b5f9cfda18119b0 685 SUPERFAMILY SSF56059 479 683 9.37E-46 T 01-11-2018 AFULGI_00013990 fece652f18a3cec7d5ff6b4ab3a3312e 346 Pfam PF03308 ArgK protein 18 312 5.3E-125 T 01-11-2018 AFULGI_00013990 fece652f18a3cec7d5ff6b4ab3a3312e 346 SUPERFAMILY SSF52540 3 335 9.18E-74 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00013990 fece652f18a3cec7d5ff6b4ab3a3312e 346 TIGRFAM TIGR00750 lao: LAO/AO transport system ATPase 13 337 2.3E-146 T 01-11-2018 IPR005129 SIMIBI class G3E GTPase, ArgK/MeaB GO:0003924|GO:0005525 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 AFULGI_00013990 fece652f18a3cec7d5ff6b4ab3a3312e 346 Gene3D G3DSA:3.40.50.300 44 280 1.2E-80 T 01-11-2018 AFULGI_00013990 fece652f18a3cec7d5ff6b4ab3a3312e 346 Gene3D G3DSA:1.20.5.170 3 42 1.4E-6 T 01-11-2018 AFULGI_00015620 c0667bb2826ab9a95c4b64aa4f0d4882 187 Gene3D G3DSA:1.10.10.10 1 47 8.1E-14 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00015620 c0667bb2826ab9a95c4b64aa4f0d4882 187 Pfam PF13412 Winged helix-turn-helix DNA-binding 1 43 1.6E-12 T 01-11-2018 AFULGI_00015620 c0667bb2826ab9a95c4b64aa4f0d4882 187 Gene3D G3DSA:3.30.70.920 52 146 1.7E-8 T 01-11-2018 AFULGI_00015620 c0667bb2826ab9a95c4b64aa4f0d4882 187 SUPERFAMILY SSF46785 1 46 1.87E-8 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00015620 c0667bb2826ab9a95c4b64aa4f0d4882 187 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 6.2E-8 T 01-11-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFULGI_00015620 c0667bb2826ab9a95c4b64aa4f0d4882 187 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 6.2E-8 T 01-11-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFULGI_00015620 c0667bb2826ab9a95c4b64aa4f0d4882 187 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 6.2E-8 T 01-11-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFULGI_00015620 c0667bb2826ab9a95c4b64aa4f0d4882 187 SMART SM00344 1 105 7.8E-35 T 01-11-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 AFULGI_00015620 c0667bb2826ab9a95c4b64aa4f0d4882 187 Pfam PF01037 Lrp/AsnC ligand binding domain 66 137 5.0E-11 T 01-11-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain AFULGI_00015620 c0667bb2826ab9a95c4b64aa4f0d4882 187 SUPERFAMILY SSF54909 60 135 5.9E-8 T 01-11-2018 IPR011008 Dimeric alpha-beta barrel AFULGI_00005900 ae904354c0932c70eb544f5e7e02c1ea 49 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 11 49 1.3E-9 T 01-11-2018 IPR007159 SpoVT-AbrB domain GO:0003677 AFULGI_00005900 ae904354c0932c70eb544f5e7e02c1ea 49 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 11 48 2.3E-7 T 01-11-2018 IPR007159 SpoVT-AbrB domain GO:0003677 AFULGI_00005900 ae904354c0932c70eb544f5e7e02c1ea 49 Gene3D G3DSA:2.10.260.10 7 47 1.4E-10 T 01-11-2018 AFULGI_00005900 ae904354c0932c70eb544f5e7e02c1ea 49 SUPERFAMILY SSF89447 9 48 2.79E-9 T 01-11-2018 IPR037914 SpoVT-AbrB domain superfamily AFULGI_00005900 ae904354c0932c70eb544f5e7e02c1ea 49 SMART SM00966 9 49 3.8E-4 T 01-11-2018 IPR007159 SpoVT-AbrB domain GO:0003677 AFULGI_00021530 e1e389bd2735c53969945da704207718 728 Pfam PF03144 Elongation factor Tu domain 2 304 370 4.7E-15 T 01-11-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 AFULGI_00021530 e1e389bd2735c53969945da704207718 728 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 59 74 - T 01-11-2018 IPR031157 Tr-type G domain, conserved site AFULGI_00021530 e1e389bd2735c53969945da704207718 728 Gene3D G3DSA:3.40.50.300 5 219 1.2E-74 T 01-11-2018 AFULGI_00021530 e1e389bd2735c53969945da704207718 728 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 21 157 2.1E-24 T 01-11-2018 IPR005225 Small GTP-binding protein domain GO:0005525 AFULGI_00021530 e1e389bd2735c53969945da704207718 728 Pfam PF03764 Elongation factor G, domain IV 508 616 2.3E-28 T 01-11-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 AFULGI_00021530 e1e389bd2735c53969945da704207718 728 Pfam PF00009 Elongation factor Tu GTP binding domain 20 256 6.5E-66 T 01-11-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFULGI_00021530 e1e389bd2735c53969945da704207718 728 SUPERFAMILY SSF54980 621 716 1.26E-24 T 01-11-2018 IPR035647 EF-G domain III/V-like AFULGI_00021530 e1e389bd2735c53969945da704207718 728 Pfam PF00679 Elongation factor G C-terminus 619 703 6.5E-24 T 01-11-2018 IPR000640 Elongation factor EFG, domain V-like AFULGI_00021530 e1e389bd2735c53969945da704207718 728 Hamap MF_00054_A Elongation factor G [fusA]. 1 722 43.298 T 01-11-2018 IPR004543 Translation elongation factor EFG/EF2, archaeal GO:0003746|GO:0005525|GO:0005737|GO:0006414 AFULGI_00021530 e1e389bd2735c53969945da704207718 728 SUPERFAMILY SSF54980 386 462 1.33E-23 T 01-11-2018 IPR035647 EF-G domain III/V-like AFULGI_00021530 e1e389bd2735c53969945da704207718 728 Gene3D G3DSA:3.30.70.240 465 715 5.9E-78 T 01-11-2018 AFULGI_00021530 e1e389bd2735c53969945da704207718 728 Gene3D G3DSA:3.30.230.10 471 718 5.9E-78 T 01-11-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AFULGI_00021530 e1e389bd2735c53969945da704207718 728 SUPERFAMILY SSF52540 7 260 4.53E-73 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00021530 e1e389bd2735c53969945da704207718 728 Pfam PF14492 Elongation Factor G, domain II 386 458 8.9E-27 T 01-11-2018 AFULGI_00021530 e1e389bd2735c53969945da704207718 728 Gene3D G3DSA:2.40.30.10 257 385 2.1E-28 T 01-11-2018 AFULGI_00021530 e1e389bd2735c53969945da704207718 728 SMART SM00889 504 616 1.9E-21 T 01-11-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 AFULGI_00021530 e1e389bd2735c53969945da704207718 728 PRINTS PR00315 GTP-binding elongation factor signature 22 35 2.1E-16 T 01-11-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFULGI_00021530 e1e389bd2735c53969945da704207718 728 PRINTS PR00315 GTP-binding elongation factor signature 142 151 2.1E-16 T 01-11-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFULGI_00021530 e1e389bd2735c53969945da704207718 728 PRINTS PR00315 GTP-binding elongation factor signature 66 74 2.1E-16 T 01-11-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFULGI_00021530 e1e389bd2735c53969945da704207718 728 PRINTS PR00315 GTP-binding elongation factor signature 90 100 2.1E-16 T 01-11-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFULGI_00021530 e1e389bd2735c53969945da704207718 728 PRINTS PR00315 GTP-binding elongation factor signature 106 117 2.1E-16 T 01-11-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFULGI_00021530 e1e389bd2735c53969945da704207718 728 SUPERFAMILY SSF50447 256 382 2.01E-32 T 01-11-2018 IPR009000 Translation protein, beta-barrel domain superfamily AFULGI_00021530 e1e389bd2735c53969945da704207718 728 SMART SM00838 618 705 9.3E-47 T 01-11-2018 IPR000640 Elongation factor EFG, domain V-like AFULGI_00021530 e1e389bd2735c53969945da704207718 728 TIGRFAM TIGR00490 aEF-2: translation elongation factor aEF-2 2 718 0.0 T 01-11-2018 IPR004543 Translation elongation factor EFG/EF2, archaeal GO:0003746|GO:0005525|GO:0005737|GO:0006414 AFULGI_00021530 e1e389bd2735c53969945da704207718 728 Gene3D G3DSA:3.30.70.870 387 462 5.1E-27 T 01-11-2018 AFULGI_00021530 e1e389bd2735c53969945da704207718 728 SUPERFAMILY SSF54211 462 620 1.64E-48 T 01-11-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFULGI_00003590 d43f753403bd11733e23dbf1ce3eca2e 450 SMART SM00487 68 231 5.7E-25 T 01-11-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFULGI_00003590 d43f753403bd11733e23dbf1ce3eca2e 450 Pfam PF16203 ERCC3/RAD25/XPB C-terminal helicase 312 443 1.9E-21 T 01-11-2018 IPR032438 ERCC3/RAD25/XPB helicase, C-terminal domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 AFULGI_00003590 d43f753403bd11733e23dbf1ce3eca2e 450 SUPERFAMILY SSF52540 88 419 3.05E-40 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00003590 d43f753403bd11733e23dbf1ce3eca2e 450 Gene3D G3DSA:3.40.50.300 59 235 1.8E-51 T 01-11-2018 AFULGI_00003590 d43f753403bd11733e23dbf1ce3eca2e 450 Pfam PF04851 Type III restriction enzyme, res subunit 70 208 9.9E-28 T 01-11-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 AFULGI_00003590 d43f753403bd11733e23dbf1ce3eca2e 450 Gene3D G3DSA:3.40.1170.30 2 58 3.7E-32 T 01-11-2018 AFULGI_00003590 d43f753403bd11733e23dbf1ce3eca2e 450 SMART SM00490 338 417 1.9E-15 T 01-11-2018 IPR001650 Helicase, C-terminal AFULGI_00003590 d43f753403bd11733e23dbf1ce3eca2e 450 Gene3D G3DSA:3.40.50.300 236 434 9.3E-53 T 01-11-2018 AFULGI_00007260 d2044167d4eb3f0015d9dacfc508a4cd 412 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 30 405 1.5E-110 T 01-11-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 AFULGI_00007260 d2044167d4eb3f0015d9dacfc508a4cd 412 SMART SM01329 29 405 1.0E-184 T 01-11-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 AFULGI_00007260 d2044167d4eb3f0015d9dacfc508a4cd 412 TIGRFAM TIGR00183 prok_nadp_idh: isocitrate dehydrogenase, NADP-dependent 2 410 3.4E-218 T 01-11-2018 IPR004439 Isocitrate dehydrogenase NADP-dependent, dimeric, prokaryotic GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 AFULGI_00007260 d2044167d4eb3f0015d9dacfc508a4cd 412 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 297 316 - T 01-11-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 AFULGI_00007260 d2044167d4eb3f0015d9dacfc508a4cd 412 SUPERFAMILY SSF53659 3 409 4.8E-143 T 01-11-2018 AFULGI_00007260 d2044167d4eb3f0015d9dacfc508a4cd 412 Gene3D G3DSA:3.40.718.10 1 412 1.0E-188 T 01-11-2018 AFULGI_00009320 ebcb39d595e437bf21427985d5b2ee15 283 Gene3D G3DSA:3.10.580.10 142 283 5.1E-28 T 01-11-2018 AFULGI_00009320 ebcb39d595e437bf21427985d5b2ee15 283 SMART SM00116 233 280 7.6E-6 T 01-11-2018 IPR000644 CBS domain AFULGI_00009320 ebcb39d595e437bf21427985d5b2ee15 283 SMART SM00116 87 135 3.0E-13 T 01-11-2018 IPR000644 CBS domain AFULGI_00009320 ebcb39d595e437bf21427985d5b2ee15 283 SMART SM00116 7 56 2.7E-6 T 01-11-2018 IPR000644 CBS domain AFULGI_00009320 ebcb39d595e437bf21427985d5b2ee15 283 SMART SM00116 151 198 3.8E-9 T 01-11-2018 IPR000644 CBS domain AFULGI_00009320 ebcb39d595e437bf21427985d5b2ee15 283 SUPERFAMILY SSF54631 80 197 5.18E-35 T 01-11-2018 AFULGI_00009320 ebcb39d595e437bf21427985d5b2ee15 283 Gene3D G3DSA:3.10.580.10 1 136 2.5E-38 T 01-11-2018 AFULGI_00009320 ebcb39d595e437bf21427985d5b2ee15 283 SUPERFAMILY SSF54631 2 55 2.95E-11 T 01-11-2018 AFULGI_00009320 ebcb39d595e437bf21427985d5b2ee15 283 Pfam PF00571 CBS domain 144 196 2.6E-14 T 01-11-2018 IPR000644 CBS domain AFULGI_00009320 ebcb39d595e437bf21427985d5b2ee15 283 Pfam PF00571 CBS domain 2 52 6.6E-9 T 01-11-2018 IPR000644 CBS domain AFULGI_00009320 ebcb39d595e437bf21427985d5b2ee15 283 Pfam PF00571 CBS domain 232 279 1.8E-10 T 01-11-2018 IPR000644 CBS domain AFULGI_00009320 ebcb39d595e437bf21427985d5b2ee15 283 Pfam PF00571 CBS domain 80 134 1.6E-15 T 01-11-2018 IPR000644 CBS domain AFULGI_00009320 ebcb39d595e437bf21427985d5b2ee15 283 SUPERFAMILY SSF54631 205 281 5.14E-10 T 01-11-2018 AFULGI_00020180 3c353c3bda1cb144ce9b9029c0ec5aa3 520 PIRSF PIRSF002741 191 520 1.4E-71 T 01-11-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 AFULGI_00020180 3c353c3bda1cb144ce9b9029c0ec5aa3 520 PIRSF PIRSF002741 4 196 4.3E-27 T 01-11-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 AFULGI_00020180 3c353c3bda1cb144ce9b9029c0ec5aa3 520 Gene3D G3DSA:3.10.105.10 10 164 7.9E-33 T 01-11-2018 AFULGI_00020180 3c353c3bda1cb144ce9b9029c0ec5aa3 520 Gene3D G3DSA:3.10.105.10 434 520 1.1E-16 T 01-11-2018 AFULGI_00020180 3c353c3bda1cb144ce9b9029c0ec5aa3 520 SUPERFAMILY SSF53850 196 518 6.15E-96 T 01-11-2018 AFULGI_00020180 3c353c3bda1cb144ce9b9029c0ec5aa3 520 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 241 519 4.8E-80 T 01-11-2018 IPR000914 Solute-binding protein family 5 domain AFULGI_00020180 3c353c3bda1cb144ce9b9029c0ec5aa3 520 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 33 116 7.8E-13 T 01-11-2018 IPR000914 Solute-binding protein family 5 domain AFULGI_00020180 3c353c3bda1cb144ce9b9029c0ec5aa3 520 Gene3D G3DSA:3.40.190.10 189 433 2.5E-71 T 01-11-2018 AFULGI_00020180 3c353c3bda1cb144ce9b9029c0ec5aa3 520 SUPERFAMILY SSF53850 30 193 4.34E-36 T 01-11-2018 AFULGI_00009660 8f8c186fc83d635cc921c7d6b52eb8d2 374 SUPERFAMILY SSF52402 164 361 8.82E-49 T 01-11-2018 AFULGI_00009660 8f8c186fc83d635cc921c7d6b52eb8d2 374 SMART SM00981 66 153 1.2E-25 T 01-11-2018 IPR004114 THUMP domain GO:0003723 AFULGI_00009660 8f8c186fc83d635cc921c7d6b52eb8d2 374 Pfam PF02926 THUMP domain 32 151 2.6E-26 T 01-11-2018 IPR004114 THUMP domain GO:0003723 AFULGI_00009660 8f8c186fc83d635cc921c7d6b52eb8d2 374 Pfam PF02568 Thiamine biosynthesis protein (ThiI) 163 358 4.0E-89 T 01-11-2018 IPR020536 Thil, AANH domain GO:0004810 KEGG: 00730+2.8.1.4 AFULGI_00009660 8f8c186fc83d635cc921c7d6b52eb8d2 374 TIGRFAM TIGR00342 TIGR00342: tRNA sulfurtransferase ThiI 7 365 9.6E-157 T 01-11-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 KEGG: 00730+2.8.1.4 AFULGI_00009660 8f8c186fc83d635cc921c7d6b52eb8d2 374 SUPERFAMILY SSF143437 4 161 5.76E-43 T 01-11-2018 AFULGI_00009660 8f8c186fc83d635cc921c7d6b52eb8d2 374 Hamap MF_00021 tRNA sulfurtransferase [thiI]. 1 374 132.651 T 01-11-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 KEGG: 00730+2.8.1.4 AFULGI_00009660 8f8c186fc83d635cc921c7d6b52eb8d2 374 Gene3D G3DSA:3.30.2130.30 2 162 6.5E-53 T 01-11-2018 AFULGI_00009660 8f8c186fc83d635cc921c7d6b52eb8d2 374 Gene3D G3DSA:3.40.50.620 163 372 2.5E-70 T 01-11-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFULGI_00021920 5937193c663189fdc98ce53e8b1edd45 178 Pfam PF01575 MaoC like domain 36 154 3.6E-35 T 01-11-2018 IPR002539 MaoC-like dehydratase domain AFULGI_00021920 5937193c663189fdc98ce53e8b1edd45 178 Gene3D G3DSA:3.10.129.10 18 178 3.3E-54 T 01-11-2018 AFULGI_00021920 5937193c663189fdc98ce53e8b1edd45 178 SUPERFAMILY SSF54637 28 174 4.34E-43 T 01-11-2018 IPR029069 HotDog domain superfamily AFULGI_00010170 7622f9f4975cb897c928f654bfd2e014 210 Pfam PF13419 Haloacid dehalogenase-like hydrolase 38 175 8.0E-16 T 01-11-2018 AFULGI_00010170 7622f9f4975cb897c928f654bfd2e014 210 SUPERFAMILY SSF56784 19 206 1.26E-35 T 01-11-2018 IPR036412 HAD-like superfamily AFULGI_00010170 7622f9f4975cb897c928f654bfd2e014 210 Gene3D G3DSA:1.10.260.80 32 82 4.2E-38 T 01-11-2018 AFULGI_00010170 7622f9f4975cb897c928f654bfd2e014 210 Gene3D G3DSA:3.40.50.1000 23 182 4.2E-38 T 01-11-2018 IPR023214 HAD superfamily AFULGI_00010170 7622f9f4975cb897c928f654bfd2e014 210 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 22 175 5.0E-11 T 01-11-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFULGI_00010170 7622f9f4975cb897c928f654bfd2e014 210 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 22 170 1.2E-11 T 01-11-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFULGI_00005520 8e4c9337c2144f7e2074cd2a09516f0b 538 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 112 123 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFULGI_00005520 8e4c9337c2144f7e2074cd2a09516f0b 538 SUPERFAMILY SSF46548 105 209 4.36E-13 T 01-11-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 AFULGI_00005520 8e4c9337c2144f7e2074cd2a09516f0b 538 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 183 194 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFULGI_00005520 8e4c9337c2144f7e2074cd2a09516f0b 538 Pfam PF02754 Cysteine-rich domain 400 499 9.3E-7 T 01-11-2018 IPR004017 Cysteine-rich domain AFULGI_00005520 8e4c9337c2144f7e2074cd2a09516f0b 538 Pfam PF13183 4Fe-4S dicluster domain 109 197 1.5E-10 T 01-11-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFULGI_00012760 179b7ef4cb8af1b00bd4856b0c1ac8ab 312 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 181 277 2.2E-22 T 01-11-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 AFULGI_00012760 179b7ef4cb8af1b00bd4856b0c1ac8ab 312 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 5 178 3.0E-49 T 01-11-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 AFULGI_00012760 179b7ef4cb8af1b00bd4856b0c1ac8ab 312 SUPERFAMILY SSF51735 5 178 4.47E-42 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily AFULGI_00012760 179b7ef4cb8af1b00bd4856b0c1ac8ab 312 Gene3D G3DSA:3.40.50.720 1 181 9.9E-51 T 01-11-2018 AFULGI_00012760 179b7ef4cb8af1b00bd4856b0c1ac8ab 312 Gene3D G3DSA:1.10.1040.10 182 298 1.0E-21 T 01-11-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AFULGI_00012760 179b7ef4cb8af1b00bd4856b0c1ac8ab 312 PIRSF PIRSF000105 1 300 4.4E-95 T 01-11-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 AFULGI_00012760 179b7ef4cb8af1b00bd4856b0c1ac8ab 312 SUPERFAMILY SSF48179 181 284 3.4E-20 T 01-11-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AFULGI_00003920 cb4a6ca45f6ec4f4f198498760e84565 149 PIRSF PIRSF018748 1 149 4.0E-40 T 01-11-2018 IPR019271 Protein of unknown function DUF2284, metal-binding AFULGI_00003920 cb4a6ca45f6ec4f4f198498760e84565 149 Pfam PF10050 Predicted metal-binding protein (DUF2284) 22 142 9.0E-21 T 01-11-2018 IPR019271 Protein of unknown function DUF2284, metal-binding AFULGI_00024930 eb9419e6f945cf70acaa229e6afe3156 516 Gene3D G3DSA:3.90.226.10 1 258 1.1E-97 T 01-11-2018 AFULGI_00024930 eb9419e6f945cf70acaa229e6afe3156 516 Pfam PF01039 Carboxyl transferase domain 27 514 5.3E-206 T 01-11-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 AFULGI_00024930 eb9419e6f945cf70acaa229e6afe3156 516 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 94 108 8.5E-5 T 01-11-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 AFULGI_00024930 eb9419e6f945cf70acaa229e6afe3156 516 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 194 205 8.5E-5 T 01-11-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 AFULGI_00024930 eb9419e6f945cf70acaa229e6afe3156 516 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 128 146 8.5E-5 T 01-11-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 AFULGI_00024930 eb9419e6f945cf70acaa229e6afe3156 516 Gene3D G3DSA:3.90.226.10 261 516 2.3E-96 T 01-11-2018 AFULGI_00024930 eb9419e6f945cf70acaa229e6afe3156 516 SUPERFAMILY SSF52096 226 516 2.26E-95 T 01-11-2018 IPR029045 ClpP/crotonase-like domain superfamily AFULGI_00024930 eb9419e6f945cf70acaa229e6afe3156 516 SUPERFAMILY SSF52096 5 256 3.27E-81 T 01-11-2018 IPR029045 ClpP/crotonase-like domain superfamily AFULGI_00024930 eb9419e6f945cf70acaa229e6afe3156 516 TIGRFAM TIGR01117 mmdA: methylmalonyl-CoA decarboxylase alpha subunit 5 516 0.0 T 01-11-2018 IPR005783 Methylmalonyl-CoA decarboxylase, alpha subunit AFULGI_00015560 80fb90659791618b40e96437d29fc897 370 Hamap MF_02067 Fructose-1,6-bisphosphate aldolase/phosphatase [fbp]. 2 368 59.667 T 01-11-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 AFULGI_00015560 80fb90659791618b40e96437d29fc897 370 PIRSF PIRSF015647 2 370 9.5E-191 T 01-11-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 AFULGI_00015560 80fb90659791618b40e96437d29fc897 370 SUPERFAMILY SSF111249 3 368 1.44E-176 T 01-11-2018 IPR036076 Fructose-1,6-bisphosphatase, class V superfamily KEGG: 00010+3.1.3.11+4.1.2.13|KEGG: 00030+3.1.3.11+4.1.2.13|KEGG: 00051+3.1.3.11+4.1.2.13|KEGG: 00680+3.1.3.11+4.1.2.13|KEGG: 00710+3.1.3.11+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 AFULGI_00015560 80fb90659791618b40e96437d29fc897 370 ProDom PD014260 DIHYDROOROTATE DEHYDROGENASE THERMOPHILE-SPECIFIC TA1428 ST0318 BLL2851 16-BISPHOSPHATASE APE1109 PF0613 MJ0299 1 367 0.0 T 01-11-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 AFULGI_00015560 80fb90659791618b40e96437d29fc897 370 Pfam PF01950 Fructose-1,6-bisphosphatase 3 368 1.8E-183 T 01-11-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 AFULGI_00019440 d97a6fa40bf04ed5522682a8a9e88adb 294 Gene3D G3DSA:1.10.1040.10 171 292 8.3E-41 T 01-11-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AFULGI_00019440 d97a6fa40bf04ed5522682a8a9e88adb 294 Pfam PF02558 Ketopantoate reductase PanE/ApbA 7 144 1.6E-32 T 01-11-2018 IPR013332 Ketopantoate reductase, N-terminal domain AFULGI_00019440 d97a6fa40bf04ed5522682a8a9e88adb 294 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 171 291 2.2E-36 T 01-11-2018 IPR013752 Ketopantoate reductase, C-terminal domain AFULGI_00019440 d97a6fa40bf04ed5522682a8a9e88adb 294 Gene3D G3DSA:3.40.50.720 5 169 3.9E-43 T 01-11-2018 AFULGI_00019440 d97a6fa40bf04ed5522682a8a9e88adb 294 SUPERFAMILY SSF51735 6 156 2.33E-16 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily AFULGI_00019440 d97a6fa40bf04ed5522682a8a9e88adb 294 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 5 292 1.2E-90 T 01-11-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0008677|GO:0015940 KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 AFULGI_00019440 d97a6fa40bf04ed5522682a8a9e88adb 294 SUPERFAMILY SSF48179 170 291 7.14E-33 T 01-11-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AFULGI_00023000 4837b33a559042b4c73cf82e6dd8f4de 363 SUPERFAMILY SSF55920 138 358 1.96E-43 T 01-11-2018 IPR036005 Creatinase/aminopeptidase-like AFULGI_00023000 4837b33a559042b4c73cf82e6dd8f4de 363 Gene3D G3DSA:3.40.350.10 1 133 1.6E-7 T 01-11-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal AFULGI_00023000 4837b33a559042b4c73cf82e6dd8f4de 363 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 294 306 - T 01-11-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site AFULGI_00023000 4837b33a559042b4c73cf82e6dd8f4de 363 Gene3D G3DSA:3.90.230.10 138 360 1.2E-50 T 01-11-2018 AFULGI_00023000 4837b33a559042b4c73cf82e6dd8f4de 363 Pfam PF00557 Metallopeptidase family M24 176 346 4.4E-39 T 01-11-2018 IPR000994 Peptidase M24 AFULGI_00023000 4837b33a559042b4c73cf82e6dd8f4de 363 SUPERFAMILY SSF53092 3 119 4.53E-6 T 01-11-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal AFULGI_00023000 4837b33a559042b4c73cf82e6dd8f4de 363 Pfam PF01321 Creatinase/Prolidase N-terminal domain 3 122 1.1E-6 T 01-11-2018 IPR000587 Creatinase, N-terminal GO:0016787 AFULGI_00011780 601d1764821ce3dbe3a5171ed1e9db02 72 Pfam PF01954 Protein of unknown function DUF104 1 42 3.4E-20 T 01-11-2018 IPR008203 Uncharacterised protein family UPF0165 AFULGI_00011780 601d1764821ce3dbe3a5171ed1e9db02 72 Gene3D G3DSA:4.10.1150.10 1 70 2.9E-20 T 01-11-2018 IPR024069 AF2212-like domain superfamily AFULGI_00011780 601d1764821ce3dbe3a5171ed1e9db02 72 SUPERFAMILY SSF141694 1 44 2.22E-16 T 01-11-2018 AFULGI_00011680 f997415868dcd31aeba0a154e0cb8a14 491 Pfam PF00474 Sodium:solute symporter family 31 437 7.3E-60 T 01-11-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 AFULGI_00011680 f997415868dcd31aeba0a154e0cb8a14 491 Gene3D G3DSA:1.20.1730.10 22 491 3.1E-68 T 01-11-2018 IPR038377 Sodium/glucose symporter superfamily AFULGI_00011680 f997415868dcd31aeba0a154e0cb8a14 491 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 31 444 1.0E-55 T 01-11-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 AFULGI_00011680 f997415868dcd31aeba0a154e0cb8a14 491 ProSitePatterns PS00456 Sodium:solute symporter family signature 1. 150 175 - T 01-11-2018 IPR018212 Sodium/solute symporter, conserved site AFULGI_00024650 dd337a38777db178690b108b4f0b6d49 61 ProDom PD052873 AF2193 1 43 9.0E-19 T 01-11-2018 IPR035258 Protein of unknown function DUF5350 AFULGI_00024650 dd337a38777db178690b108b4f0b6d49 61 Pfam PF17299 Family of unknown function (DUF5350) 1 57 6.1E-27 T 01-11-2018 IPR035258 Protein of unknown function DUF5350 AFULGI_00012350 fa9b4e3f2eb0d2b0ce920bed78d0ab86 294 SUPERFAMILY SSF52540 4 222 1.28E-63 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00012350 fa9b4e3f2eb0d2b0ce920bed78d0ab86 294 Gene3D G3DSA:3.40.50.300 1 229 8.6E-68 T 01-11-2018 AFULGI_00012350 fa9b4e3f2eb0d2b0ce920bed78d0ab86 294 Pfam PF00005 ABC transporter 19 159 2.8E-30 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFULGI_00012350 fa9b4e3f2eb0d2b0ce920bed78d0ab86 294 SMART SM00382 28 229 6.9E-13 T 01-11-2018 IPR003593 AAA+ ATPase domain AFULGI_00013670 3f808c9a6ec82668a2878bc392189b04 249 Pfam PF09968 Uncharacterized protein domain (DUF2202) 81 242 1.3E-71 T 01-11-2018 IPR019243 Domain of unknown function DUF2202 AFULGI_00013670 3f808c9a6ec82668a2878bc392189b04 249 SUPERFAMILY SSF47240 82 221 2.68E-11 T 01-11-2018 IPR009078 Ferritin-like superfamily AFULGI_00013670 3f808c9a6ec82668a2878bc392189b04 249 Gene3D G3DSA:1.20.1260.10 76 249 1.7E-72 T 01-11-2018 IPR012347 Ferritin-like AFULGI_00023690 518f799fc0e48ef5817b89e6dfe3fcf4 402 Pfam PF00107 Zinc-binding dehydrogenase 215 348 1.0E-28 T 01-11-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 AFULGI_00023690 518f799fc0e48ef5817b89e6dfe3fcf4 402 SUPERFAMILY SSF51735 181 344 3.54E-28 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily AFULGI_00023690 518f799fc0e48ef5817b89e6dfe3fcf4 402 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 87 101 - T 01-11-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 AFULGI_00023690 518f799fc0e48ef5817b89e6dfe3fcf4 402 Gene3D G3DSA:3.90.180.10 43 381 2.4E-85 T 01-11-2018 AFULGI_00023690 518f799fc0e48ef5817b89e6dfe3fcf4 402 Gene3D G3DSA:3.40.50.720 192 337 2.4E-85 T 01-11-2018 AFULGI_00023690 518f799fc0e48ef5817b89e6dfe3fcf4 402 SUPERFAMILY SSF50129 35 213 3.98E-37 T 01-11-2018 IPR011032 GroES-like superfamily AFULGI_00023690 518f799fc0e48ef5817b89e6dfe3fcf4 402 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 49 174 5.4E-25 T 01-11-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 AFULGI_00016270 e7be74cb3f7b291e108faa8d7b2f754c 194 Gene3D G3DSA:3.60.15.10 4 174 2.8E-5 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFULGI_00016270 e7be74cb3f7b291e108faa8d7b2f754c 194 SUPERFAMILY SSF56281 19 126 2.11E-6 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFULGI_00007460 d7295ee843dfff1c78a7ba06e6f4d6cf 106 Gene3D G3DSA:1.10.10.10 41 90 5.2E-9 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00007460 d7295ee843dfff1c78a7ba06e6f4d6cf 106 Pfam PF02001 Protein of unknown function DUF134 11 105 1.9E-40 T 01-11-2018 IPR002852 Uncharacterised protein family UPF0251 AFULGI_00007460 d7295ee843dfff1c78a7ba06e6f4d6cf 106 SUPERFAMILY SSF88659 45 87 2.24E-7 T 01-11-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFULGI_00026700 613946d3883922d7716ddc23600e5b3f 203 Pfam PF00753 Metallo-beta-lactamase superfamily 105 180 5.5E-10 T 01-11-2018 IPR001279 Metallo-beta-lactamase AFULGI_00026700 613946d3883922d7716ddc23600e5b3f 203 Pfam PF00753 Metallo-beta-lactamase superfamily 18 78 2.7E-7 T 01-11-2018 IPR001279 Metallo-beta-lactamase AFULGI_00026700 613946d3883922d7716ddc23600e5b3f 203 SUPERFAMILY SSF56281 2 201 2.44E-39 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFULGI_00026700 613946d3883922d7716ddc23600e5b3f 203 SMART SM00849 19 180 3.9E-28 T 01-11-2018 IPR001279 Metallo-beta-lactamase AFULGI_00026700 613946d3883922d7716ddc23600e5b3f 203 Gene3D G3DSA:3.60.15.10 1 202 1.4E-37 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFULGI_00017690 adb1f9410e0d6021616895af8662b056 219 Gene3D G3DSA:2.40.50.580 1 78 4.3E-30 T 01-11-2018 AFULGI_00017690 adb1f9410e0d6021616895af8662b056 219 Pfam PF03749 Sugar fermentation stimulation protein 15 200 4.0E-42 T 01-11-2018 IPR005224 Sugar fermentation stimulation protein AFULGI_00017690 adb1f9410e0d6021616895af8662b056 219 Gene3D G3DSA:3.40.1350.60 79 217 5.7E-24 T 01-11-2018 AFULGI_00017690 adb1f9410e0d6021616895af8662b056 219 TIGRFAM TIGR00230 sfsA: sugar fermentation stimulation protein 1 219 3.4E-89 T 01-11-2018 IPR005224 Sugar fermentation stimulation protein AFULGI_00005380 345ae2b9ee8a2b4019785ab283d12d13 74 Gene3D G3DSA:1.10.10.10 1 73 9.1E-9 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00005380 345ae2b9ee8a2b4019785ab283d12d13 74 SUPERFAMILY SSF46785 8 68 3.94E-10 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00005380 345ae2b9ee8a2b4019785ab283d12d13 74 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 15 63 9.5E-7 T 01-11-2018 IPR002831 Transcription regulator TrmB, N-terminal AFULGI_00019760 9b5797f11c2ffd37615ec7ec005fa017 303 Pfam PF01068 ATP dependent DNA ligase domain 9 186 6.2E-40 T 01-11-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 AFULGI_00019760 9b5797f11c2ffd37615ec7ec005fa017 303 Pfam PF04679 ATP dependent DNA ligase C terminal region 205 295 2.1E-26 T 01-11-2018 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 AFULGI_00019760 9b5797f11c2ffd37615ec7ec005fa017 303 Gene3D G3DSA:3.30.470.30 22 142 1.3E-42 T 01-11-2018 AFULGI_00019760 9b5797f11c2ffd37615ec7ec005fa017 303 SUPERFAMILY SSF50249 189 300 5.25E-32 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold AFULGI_00019760 9b5797f11c2ffd37615ec7ec005fa017 303 Gene3D G3DSA:2.40.50.140 188 302 8.8E-38 T 01-11-2018 AFULGI_00019760 9b5797f11c2ffd37615ec7ec005fa017 303 SUPERFAMILY SSF56091 6 186 1.55E-37 T 01-11-2018 AFULGI_00019760 9b5797f11c2ffd37615ec7ec005fa017 303 Gene3D G3DSA:3.30.1490.70 7 184 1.3E-42 T 01-11-2018 AFULGI_00019760 9b5797f11c2ffd37615ec7ec005fa017 303 TIGRFAM TIGR02779 NHEJ_ligase_lig: DNA ligase D, ligase domain 1 301 5.6E-97 T 01-11-2018 IPR014146 DNA ligase D, ligase domain AFULGI_00014900 a165739648a3cc2007556b9d25ec41ef 155 TIGRFAM TIGR00072 hydrog_prot: hydrogenase maturation protease 1 131 2.7E-33 T 01-11-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 AFULGI_00014900 a165739648a3cc2007556b9d25ec41ef 155 Pfam PF01750 Hydrogenase maturation protease 8 131 8.5E-34 T 01-11-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 AFULGI_00014900 a165739648a3cc2007556b9d25ec41ef 155 Gene3D G3DSA:3.40.50.1450 1 139 7.1E-33 T 01-11-2018 IPR023430 Peptidase HybD-like domain superfamily AFULGI_00014900 a165739648a3cc2007556b9d25ec41ef 155 PRINTS PR00446 Hydrogen uptake protein signature 3 14 3.1E-16 T 01-11-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 AFULGI_00014900 a165739648a3cc2007556b9d25ec41ef 155 PRINTS PR00446 Hydrogen uptake protein signature 22 39 3.1E-16 T 01-11-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 AFULGI_00014900 a165739648a3cc2007556b9d25ec41ef 155 PRINTS PR00446 Hydrogen uptake protein signature 54 70 3.1E-16 T 01-11-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 AFULGI_00014900 a165739648a3cc2007556b9d25ec41ef 155 PRINTS PR00446 Hydrogen uptake protein signature 43 53 3.1E-16 T 01-11-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 AFULGI_00014900 a165739648a3cc2007556b9d25ec41ef 155 SUPERFAMILY SSF53163 1 133 3.66E-31 T 01-11-2018 IPR023430 Peptidase HybD-like domain superfamily AFULGI_00017710 022a6191e244732efbe8d731af022222 189 Pfam PF02441 Flavoprotein 7 131 1.1E-17 T 01-11-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 AFULGI_00017710 022a6191e244732efbe8d731af022222 189 Gene3D G3DSA:3.40.50.1950 3 188 3.8E-44 T 01-11-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 AFULGI_00017710 022a6191e244732efbe8d731af022222 189 TIGRFAM TIGR02699 archaeo_AfpA: archaeoflavoprotein AfpA 8 182 5.3E-93 T 01-11-2018 IPR014072 Archaeoflavoprotein AfpA AFULGI_00017710 022a6191e244732efbe8d731af022222 189 SUPERFAMILY SSF52507 4 135 6.28E-26 T 01-11-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 AFULGI_00023620 f239766a42aede201616e3863a2e2b40 90 Gene3D G3DSA:2.30.30.580 1 90 2.8E-48 T 01-11-2018 AFULGI_00012780 0b88267e45ed534a8dbbba862412362a 106 SUPERFAMILY SSF101386 1 102 4.25E-31 T 01-11-2018 AFULGI_00012780 0b88267e45ed534a8dbbba862412362a 106 Gene3D G3DSA:1.10.287.1080 1 106 5.8E-39 T 01-11-2018 AFULGI_00012780 0b88267e45ed534a8dbbba862412362a 106 Pfam PF12643 MazG-like family 28 104 7.3E-17 T 01-11-2018 IPR025984 dCTP pyrophosphatase 1 GO:0009143|GO:0047429 KEGG: 00240+3.6.1.12|Reactome: R-HSA-499943 AFULGI_00012780 0b88267e45ed534a8dbbba862412362a 106 PIRSF PIRSF029826 1 106 8.4E-39 T 01-11-2018 IPR025984 dCTP pyrophosphatase 1 GO:0009143|GO:0047429 KEGG: 00240+3.6.1.12|Reactome: R-HSA-499943 AFULGI_00020150 573b008547a29a0e6a1c7efdf461b6a3 157 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 6 124 1.2E-31 T 01-11-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain AFULGI_00020150 573b008547a29a0e6a1c7efdf461b6a3 157 Gene3D G3DSA:3.40.140.10 1 157 5.4E-54 T 01-11-2018 AFULGI_00020150 573b008547a29a0e6a1c7efdf461b6a3 157 SUPERFAMILY SSF53927 7 151 1.24E-46 T 01-11-2018 IPR016193 Cytidine deaminase-like GO:0003824 AFULGI_00020150 573b008547a29a0e6a1c7efdf461b6a3 157 PIRSF PIRSF006019 1 157 4.8E-58 T 01-11-2018 IPR016473 Deoxycytidylate deaminase GO:0004132|GO:0006220|GO:0008270 KEGG: 00240+3.5.4.12|MetaCyc: PWY-7210|Reactome: R-HSA-499943 AFULGI_00020150 573b008547a29a0e6a1c7efdf461b6a3 157 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 78 113 - T 01-11-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 AFULGI_00005210 c55b7611c724acf4621ea04d09cde383 129 SMART SM01405 3 125 1.3E-56 T 01-11-2018 IPR001377 Ribosomal protein S6e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-166208|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00005210 c55b7611c724acf4621ea04d09cde383 129 ProSitePatterns PS00578 Ribosomal protein S6e signature. 52 63 - T 01-11-2018 IPR018282 Ribosomal protein S6e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-166208|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00005210 c55b7611c724acf4621ea04d09cde383 129 Pfam PF01092 Ribosomal protein S6e 3 123 1.2E-38 T 01-11-2018 IPR001377 Ribosomal protein S6e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-166208|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00005210 c55b7611c724acf4621ea04d09cde383 129 Hamap MF_00512 30S ribosomal protein S6e [rps6e]. 1 114 18.509 T 01-11-2018 IPR020924 Ribosomal protein S6e, archaeal GO:0003735|GO:0005840|GO:0006412 AFULGI_00014610 672763c6d0b7f47007f006df104af773 265 SUPERFAMILY SSF56281 34 243 3.93E-33 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFULGI_00014610 672763c6d0b7f47007f006df104af773 265 Gene3D G3DSA:3.60.15.10 7 221 1.3E-29 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFULGI_00014610 672763c6d0b7f47007f006df104af773 265 Pfam PF00753 Metallo-beta-lactamase superfamily 34 163 5.2E-18 T 01-11-2018 IPR001279 Metallo-beta-lactamase AFULGI_00014610 672763c6d0b7f47007f006df104af773 265 SMART SM00849 24 192 2.0E-24 T 01-11-2018 IPR001279 Metallo-beta-lactamase AFULGI_00026950 cd63e5635c26d57c25b50897f14d719e 372 SMART SM00226 255 369 1.8E-40 T 01-11-2018 IPR023485 Phosphotyrosine protein phosphatase I AFULGI_00026950 cd63e5635c26d57c25b50897f14d719e 372 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 257 334 1.5E-11 T 01-11-2018 IPR023485 Phosphotyrosine protein phosphatase I AFULGI_00026950 cd63e5635c26d57c25b50897f14d719e 372 Pfam PF00149 Calcineurin-like phosphoesterase 1 179 1.8E-16 T 01-11-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 AFULGI_00026950 cd63e5635c26d57c25b50897f14d719e 372 SUPERFAMILY SSF52788 253 370 1.7E-21 T 01-11-2018 IPR036196 Phosphotyrosine protein phosphatase I superfamily AFULGI_00026950 cd63e5635c26d57c25b50897f14d719e 372 Gene3D G3DSA:3.40.50.2300 252 371 1.7E-21 T 01-11-2018 AFULGI_00026950 cd63e5635c26d57c25b50897f14d719e 372 SUPERFAMILY SSF56300 1 228 1.7E-46 T 01-11-2018 AFULGI_00026950 cd63e5635c26d57c25b50897f14d719e 372 Gene3D G3DSA:3.60.21.10 1 246 5.6E-34 T 01-11-2018 IPR029052 Metallo-dependent phosphatase-like AFULGI_00015440 35f79223f3f491e25f9280051814a676 49 Pfam PF01020 Ribosomal L40e family 14 44 2.2E-4 T 01-11-2018 IPR001975 Ribosomal protein L40e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 AFULGI_00015440 35f79223f3f491e25f9280051814a676 49 SMART SM01377 1 46 1.5E-8 T 01-11-2018 IPR001975 Ribosomal protein L40e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 AFULGI_00015440 35f79223f3f491e25f9280051814a676 49 Hamap MF_00788 50S ribosomal protein L40e [rpl40e]. 2 47 19.399 T 01-11-2018 IPR023657 Ribosomal protein L40e, archaeal GO:0003735|GO:0005840|GO:0006412 AFULGI_00015440 35f79223f3f491e25f9280051814a676 49 SUPERFAMILY SSF57829 2 47 8.61E-16 T 01-11-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 AFULGI_00015440 35f79223f3f491e25f9280051814a676 49 Gene3D G3DSA:2.20.28.70 1 48 2.0E-17 T 01-11-2018 IPR038587 Ribosomal protein L40e superfamily Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 AFULGI_00023210 32c31b7db38aec0bb46c166bedc32d55 354 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 242 335 1.4E-25 T 01-11-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II AFULGI_00023210 32c31b7db38aec0bb46c166bedc32d55 354 SUPERFAMILY SSF52518 3 202 3.36E-59 T 01-11-2018 IPR029061 Thiamin diphosphate-binding fold AFULGI_00023210 32c31b7db38aec0bb46c166bedc32d55 354 SUPERFAMILY SSF52922 232 348 7.28E-23 T 01-11-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 AFULGI_00023210 32c31b7db38aec0bb46c166bedc32d55 354 Gene3D G3DSA:3.40.50.920 235 353 2.4E-21 T 01-11-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 AFULGI_00023210 32c31b7db38aec0bb46c166bedc32d55 354 Gene3D G3DSA:3.40.50.970 1 234 1.8E-79 T 01-11-2018 AFULGI_00023210 32c31b7db38aec0bb46c166bedc32d55 354 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 14 228 1.4E-72 T 01-11-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 AFULGI_00012480 c67e1caf84661b4789f1281b95080e57 916 SUPERFAMILY SSF52540 52 372 2.21E-52 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00012480 c67e1caf84661b4789f1281b95080e57 916 SMART SM00490 284 361 6.3E-19 T 01-11-2018 IPR001650 Helicase, C-terminal AFULGI_00012480 c67e1caf84661b4789f1281b95080e57 916 Gene3D G3DSA:3.40.50.300 246 392 4.5E-30 T 01-11-2018 AFULGI_00012480 c67e1caf84661b4789f1281b95080e57 916 Pfam PF00270 DEAD/DEAH box helicase 43 209 3.8E-34 T 01-11-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 AFULGI_00012480 c67e1caf84661b4789f1281b95080e57 916 SMART SM00487 38 238 4.0E-43 T 01-11-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFULGI_00012480 c67e1caf84661b4789f1281b95080e57 916 Pfam PF00271 Helicase conserved C-terminal domain 265 361 1.3E-19 T 01-11-2018 IPR001650 Helicase, C-terminal AFULGI_00012480 c67e1caf84661b4789f1281b95080e57 916 PIRSF PIRSF037307 11 916 0.0 T 01-11-2018 IPR017170 Lhr-like ATP-dependent RNA helicase, predicted GO:0005524|GO:0016818 AFULGI_00012480 c67e1caf84661b4789f1281b95080e57 916 Pfam PF08494 DEAD/H associated 606 774 1.5E-30 T 01-11-2018 IPR013701 DEAD/H associated GO:0005524|GO:0016818 AFULGI_00012480 c67e1caf84661b4789f1281b95080e57 916 Gene3D G3DSA:3.40.50.300 24 229 1.3E-50 T 01-11-2018 AFULGI_00017120 0e020c1c8f9ee9a585a312788d54f352 405 SUPERFAMILY SSF56349 122 305 2.65E-38 T 01-11-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 AFULGI_00017120 0e020c1c8f9ee9a585a312788d54f352 405 Gene3D G3DSA:1.10.443.10 120 318 9.9E-32 T 01-11-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 AFULGI_00017120 0e020c1c8f9ee9a585a312788d54f352 405 Pfam PF13495 Phage integrase, N-terminal SAM-like domain 31 111 1.1E-7 T 01-11-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 AFULGI_00017120 0e020c1c8f9ee9a585a312788d54f352 405 Pfam PF00589 Phage integrase family 128 293 1.9E-23 T 01-11-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 AFULGI_00022160 67d96a90bdd0515b5e7b65543ca055b3 329 Gene3D G3DSA:3.40.50.11900 184 329 3.2E-39 T 01-11-2018 AFULGI_00022160 67d96a90bdd0515b5e7b65543ca055b3 329 Pfam PF06050 2-hydroxyglutaryl-CoA dehydratase, D-component 7 327 3.6E-46 T 01-11-2018 IPR010327 FldB/FldC dehydratase alpha/beta subunit AFULGI_00022160 67d96a90bdd0515b5e7b65543ca055b3 329 Gene3D G3DSA:3.40.50.11890 2 121 1.1E-31 T 01-11-2018 AFULGI_00016750 d817ef47f22e916ad16a274cc0c2ef92 124 Pfam PF01609 Transposase DDE domain 47 114 3.5E-7 T 01-11-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 AFULGI_00023540 e6181c785d95dc0971b3f1571c51c26f 142 Pfam PF00364 Biotin-requiring enzyme 66 138 1.7E-21 T 01-11-2018 IPR000089 Biotin/lipoyl attachment AFULGI_00023540 e6181c785d95dc0971b3f1571c51c26f 142 Gene3D G3DSA:2.40.50.100 65 138 1.1E-24 T 01-11-2018 AFULGI_00023540 e6181c785d95dc0971b3f1571c51c26f 142 SUPERFAMILY SSF51230 67 138 3.27E-23 T 01-11-2018 IPR011053 Single hybrid motif AFULGI_00009170 2ce507ea304cd91b39b012e06d366f0e 190 Gene3D G3DSA:2.20.28.10 145 186 7.0E-17 T 01-11-2018 AFULGI_00009170 2ce507ea304cd91b39b012e06d366f0e 190 Gene3D G3DSA:1.20.1260.10 1 144 2.5E-51 T 01-11-2018 IPR012347 Ferritin-like AFULGI_00009170 2ce507ea304cd91b39b012e06d366f0e 190 SUPERFAMILY SSF57802 146 184 4.53E-11 T 01-11-2018 AFULGI_00009170 2ce507ea304cd91b39b012e06d366f0e 190 Pfam PF02915 Rubrerythrin 5 137 4.3E-38 T 01-11-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 AFULGI_00009170 2ce507ea304cd91b39b012e06d366f0e 190 SUPERFAMILY SSF47240 3 145 7.69E-37 T 01-11-2018 IPR009078 Ferritin-like superfamily AFULGI_00012500 26df6dc39bebf9a4308fc255dea48b4c 116 Pfam PF01920 Prefoldin subunit 9 112 3.0E-28 T 01-11-2018 IPR002777 Prefoldin beta-like GO:0006457|GO:0016272|GO:0051082 Reactome: R-HSA-389957 AFULGI_00012500 26df6dc39bebf9a4308fc255dea48b4c 116 Hamap MF_00307 Prefoldin subunit beta [pfdB]. 1 116 52.677 T 01-11-2018 IPR012713 Prefoldin subunit beta GO:0006457|GO:0016272|GO:0051082 AFULGI_00012500 26df6dc39bebf9a4308fc255dea48b4c 116 Gene3D G3DSA:1.10.287.370 1 116 5.4E-41 T 01-11-2018 IPR009053 Prefoldin AFULGI_00012500 26df6dc39bebf9a4308fc255dea48b4c 116 SUPERFAMILY SSF46579 6 111 6.28E-26 T 01-11-2018 AFULGI_00012500 26df6dc39bebf9a4308fc255dea48b4c 116 TIGRFAM TIGR02338 gimC_beta: prefoldin, beta subunit 4 112 5.7E-44 T 01-11-2018 IPR012713 Prefoldin subunit beta GO:0006457|GO:0016272|GO:0051082 AFULGI_00016870 b4830aa1caa375eb94567ea1450a30ec 339 Gene3D G3DSA:3.60.20.10 1 259 6.9E-82 T 01-11-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFULGI_00016870 b4830aa1caa375eb94567ea1450a30ec 339 Pfam PF13230 Glutamine amidotransferases class-II 1 255 1.4E-81 T 01-11-2018 IPR026869 Putative glutamine amidotransferase type 2 AFULGI_00016870 b4830aa1caa375eb94567ea1450a30ec 339 SUPERFAMILY SSF56235 2 256 7.63E-32 T 01-11-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFULGI_00003040 5a6b023d54cf3b4449c489fd894f6261 1395 SUPERFAMILY SSF53448 1316 1383 8.34E-22 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFULGI_00003040 5a6b023d54cf3b4449c489fd894f6261 1395 Pfam PF14307 Glycosyltransferase WbsX 581 917 1.5E-130 T 01-11-2018 IPR032719 Glycosyltransferase WbsX AFULGI_00003040 5a6b023d54cf3b4449c489fd894f6261 1395 Gene3D G3DSA:1.20.5.340 246 379 6.7E-6 T 01-11-2018 AFULGI_00003040 5a6b023d54cf3b4449c489fd894f6261 1395 Gene3D G3DSA:3.40.50.2000 940 1105 6.7E-10 T 01-11-2018 AFULGI_00003040 5a6b023d54cf3b4449c489fd894f6261 1395 SUPERFAMILY SSF53335 24 194 1.99E-33 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFULGI_00003040 5a6b023d54cf3b4449c489fd894f6261 1395 Gene3D G3DSA:3.40.50.2000 1106 1296 2.0E-35 T 01-11-2018 AFULGI_00003040 5a6b023d54cf3b4449c489fd894f6261 1395 SUPERFAMILY SSF53756 943 1311 6.28E-55 T 01-11-2018 AFULGI_00003040 5a6b023d54cf3b4449c489fd894f6261 1395 Pfam PF00534 Glycosyl transferases group 1 1118 1289 3.6E-28 T 01-11-2018 IPR001296 Glycosyl transferase, family 1 AFULGI_00003040 5a6b023d54cf3b4449c489fd894f6261 1395 Pfam PF13847 Methyltransferase domain 38 158 3.1E-22 T 01-11-2018 IPR025714 Methyltransferase domain AFULGI_00003040 5a6b023d54cf3b4449c489fd894f6261 1395 Gene3D G3DSA:3.20.20.80 576 932 4.5E-13 T 01-11-2018 AFULGI_00003040 5a6b023d54cf3b4449c489fd894f6261 1395 Gene3D G3DSA:3.40.50.150 28 201 1.0E-34 T 01-11-2018 AFULGI_00003040 5a6b023d54cf3b4449c489fd894f6261 1395 Pfam PF00535 Glycosyl transferase family 2 1319 1383 3.0E-15 T 01-11-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 AFULGI_00003040 5a6b023d54cf3b4449c489fd894f6261 1395 Gene3D G3DSA:3.90.550.10 1314 1387 5.7E-21 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFULGI_00003040 5a6b023d54cf3b4449c489fd894f6261 1395 SUPERFAMILY SSF57997 259 457 2.55E-7 T 01-11-2018 AFULGI_00003040 5a6b023d54cf3b4449c489fd894f6261 1395 Pfam PF13439 Glycosyltransferase Family 4 1017 1102 2.5E-8 T 01-11-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 AFULGI_00005510 1cda519de08a0d0a026616072b8ed182 204 SUPERFAMILY SSF102114 13 149 2.94E-6 T 01-11-2018 AFULGI_00023350 8319bc9debafad7443421e15e4447e70 50 ProSitePatterns PS00051 Ribosomal protein L39e signature. 29 45 - T 01-11-2018 IPR020083 Ribosomal protein L39e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00023350 8319bc9debafad7443421e15e4447e70 50 Gene3D G3DSA:1.10.1620.10 1 49 1.2E-18 T 01-11-2018 IPR023626 Ribosomal protein L39e domain superfamily AFULGI_00023350 8319bc9debafad7443421e15e4447e70 50 Pfam PF00832 Ribosomal L39 protein 8 49 1.2E-19 T 01-11-2018 IPR000077 Ribosomal protein L39e GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFULGI_00023350 8319bc9debafad7443421e15e4447e70 50 SUPERFAMILY SSF48662 2 50 6.67E-19 T 01-11-2018 IPR023626 Ribosomal protein L39e domain superfamily AFULGI_00023350 8319bc9debafad7443421e15e4447e70 50 Hamap MF_00629 50S ribosomal protein L39e [rpl39e]. 1 50 16.58 T 01-11-2018 IPR000077 Ribosomal protein L39e GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFULGI_00003450 b3e3c1e919373465aded5e9006c8dcda 203 SUPERFAMILY SSF55008 138 200 7.46E-10 T 01-11-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 AFULGI_00003450 b3e3c1e919373465aded5e9006c8dcda 203 Pfam PF00403 Heavy-metal-associated domain 141 196 3.2E-8 T 01-11-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 AFULGI_00003450 b3e3c1e919373465aded5e9006c8dcda 203 Gene3D G3DSA:1.10.10.1100 61 129 9.7E-30 T 01-11-2018 AFULGI_00003450 b3e3c1e919373465aded5e9006c8dcda 203 Gene3D G3DSA:3.30.70.100 138 201 1.7E-13 T 01-11-2018 AFULGI_00003450 b3e3c1e919373465aded5e9006c8dcda 203 Gene3D G3DSA:2.20.25.270 1 60 7.2E-32 T 01-11-2018 AFULGI_00003450 b3e3c1e919373465aded5e9006c8dcda 203 ProSitePatterns PS01047 Heavy-metal-associated domain. 143 171 - T 01-11-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 AFULGI_00004580 a0efbbe8ab08a80fc631943440a938b6 370 PRINTS PR01874 DNA repair protein radA signature 218 235 6.2E-7 T 01-11-2018 AFULGI_00004580 a0efbbe8ab08a80fc631943440a938b6 370 PRINTS PR01874 DNA repair protein radA signature 176 204 6.2E-7 T 01-11-2018 AFULGI_00004580 a0efbbe8ab08a80fc631943440a938b6 370 Gene3D G3DSA:3.40.50.300 1 158 4.0E-20 T 01-11-2018 AFULGI_00004580 a0efbbe8ab08a80fc631943440a938b6 370 Gene3D G3DSA:3.40.50.300 159 368 2.7E-36 T 01-11-2018 AFULGI_00004580 a0efbbe8ab08a80fc631943440a938b6 370 SMART SM00382 184 335 0.0087 T 01-11-2018 IPR003593 AAA+ ATPase domain AFULGI_00004580 a0efbbe8ab08a80fc631943440a938b6 370 SUPERFAMILY SSF52540 165 358 4.92E-28 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00004580 a0efbbe8ab08a80fc631943440a938b6 370 Pfam PF06745 KaiC 1 152 4.1E-32 T 01-11-2018 IPR014774 KaiC-like domain AFULGI_00004580 a0efbbe8ab08a80fc631943440a938b6 370 Pfam PF06745 KaiC 168 358 2.1E-20 T 01-11-2018 IPR014774 KaiC-like domain AFULGI_00004580 a0efbbe8ab08a80fc631943440a938b6 370 SUPERFAMILY SSF52540 16 149 1.56E-10 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00003880 984a562318486cc8f194da95f46bec0c 305 TIGRFAM TIGR04182 glyco_TIGR04182: glycosyltransferase, TIGR04182 family 2 290 3.3E-124 T 01-11-2018 IPR026456 Glycosyltransferase AglJ GO:0016757 AFULGI_00003880 984a562318486cc8f194da95f46bec0c 305 Gene3D G3DSA:3.90.550.10 1 225 4.3E-51 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFULGI_00003880 984a562318486cc8f194da95f46bec0c 305 Pfam PF00535 Glycosyl transferase family 2 4 156 4.2E-24 T 01-11-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 AFULGI_00003880 984a562318486cc8f194da95f46bec0c 305 SUPERFAMILY SSF53448 1 248 3.16E-42 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFULGI_00006200 0064c66457588c73bd2f598f096751e9 433 SMART SM00933 55 401 2.9E-22 T 01-11-2018 IPR018977 NurA domain AFULGI_00006200 0064c66457588c73bd2f598f096751e9 433 Pfam PF09376 NurA domain 56 279 3.0E-18 T 01-11-2018 IPR018977 NurA domain AFULGI_00021910 e54e8d32341d2a64bea8a66080bd7f77 509 Gene3D G3DSA:3.30.300.30 405 506 2.1E-22 T 01-11-2018 AFULGI_00021910 e54e8d32341d2a64bea8a66080bd7f77 509 Pfam PF13193 AMP-binding enzyme C-terminal domain 418 493 3.6E-16 T 01-11-2018 IPR025110 AMP-binding enzyme, C-terminal domain AFULGI_00021910 e54e8d32341d2a64bea8a66080bd7f77 509 SUPERFAMILY SSF56801 6 506 1.83E-129 T 01-11-2018 AFULGI_00021910 e54e8d32341d2a64bea8a66080bd7f77 509 Pfam PF00501 AMP-binding enzyme 13 409 2.2E-90 T 01-11-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFULGI_00021910 e54e8d32341d2a64bea8a66080bd7f77 509 Gene3D G3DSA:3.40.50.12780 4 404 3.5E-96 T 01-11-2018 AFULGI_00021910 e54e8d32341d2a64bea8a66080bd7f77 509 ProSitePatterns PS00455 Putative AMP-binding domain signature. 163 174 - T 01-11-2018 IPR020845 AMP-binding, conserved site AFULGI_00009310 f432b8f8ebc6b31fd1aa4af58de6b5ee 189 Pfam PF00571 CBS domain 7 61 1.0E-11 T 01-11-2018 IPR000644 CBS domain AFULGI_00009310 f432b8f8ebc6b31fd1aa4af58de6b5ee 189 Pfam PF00571 CBS domain 72 126 2.2E-17 T 01-11-2018 IPR000644 CBS domain AFULGI_00009310 f432b8f8ebc6b31fd1aa4af58de6b5ee 189 Gene3D G3DSA:3.10.580.10 2 156 1.2E-42 T 01-11-2018 AFULGI_00009310 f432b8f8ebc6b31fd1aa4af58de6b5ee 189 SUPERFAMILY SSF54631 4 126 3.79E-36 T 01-11-2018 AFULGI_00009310 f432b8f8ebc6b31fd1aa4af58de6b5ee 189 SMART SM00116 79 127 3.0E-16 T 01-11-2018 IPR000644 CBS domain AFULGI_00009310 f432b8f8ebc6b31fd1aa4af58de6b5ee 189 SMART SM00116 14 61 5.1E-7 T 01-11-2018 IPR000644 CBS domain AFULGI_00010910 ae4c6cfc1b8af4afc6ba147d82035da4 416 SUPERFAMILY SSF51338 3 412 7.48E-18 T 01-11-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 AFULGI_00010910 ae4c6cfc1b8af4afc6ba147d82035da4 416 Hamap MF_01281 5'-deoxyadenosine deaminase [dadD]. 3 414 42.256 T 01-11-2018 IPR023512 Deaminase MtaD/DadD GO:0019239 AFULGI_00010910 ae4c6cfc1b8af4afc6ba147d82035da4 416 Gene3D G3DSA:3.20.20.140 53 338 7.5E-125 T 01-11-2018 AFULGI_00010910 ae4c6cfc1b8af4afc6ba147d82035da4 416 Gene3D G3DSA:2.30.40.10 20 406 7.5E-125 T 01-11-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 AFULGI_00010910 ae4c6cfc1b8af4afc6ba147d82035da4 416 SUPERFAMILY SSF51556 52 341 5.79E-96 T 01-11-2018 IPR032466 Metal-dependent hydrolase AFULGI_00010910 ae4c6cfc1b8af4afc6ba147d82035da4 416 Pfam PF01979 Amidohydrolase family 49 363 1.7E-74 T 01-11-2018 IPR006680 Amidohydrolase-related GO:0016787 AFULGI_00004480 2b827451792a6fe0e6a856268d6ab9ed 223 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 7 189 1.5E-19 T 01-11-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 AFULGI_00004480 2b827451792a6fe0e6a856268d6ab9ed 223 Gene3D G3DSA:3.40.50.1000 7 208 3.3E-62 T 01-11-2018 IPR023214 HAD superfamily AFULGI_00004480 2b827451792a6fe0e6a856268d6ab9ed 223 TIGRFAM TIGR01482 SPP-subfamily: sucrose-phosphate phosphatase subfamily 7 220 2.3E-83 T 01-11-2018 AFULGI_00004480 2b827451792a6fe0e6a856268d6ab9ed 223 TIGRFAM TIGR01487 Pglycolate_arch: phosphoglycolate phosphatase, TA0175-type 5 216 1.2E-89 T 01-11-2018 AFULGI_00004480 2b827451792a6fe0e6a856268d6ab9ed 223 Hamap MF_01419 Phosphoglycolate phosphatase. 4 221 32.989 T 01-11-2018 IPR006382 Phosphoglycolate phosphatase GO:0000287|GO:0008967|GO:0016311 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181 AFULGI_00004480 2b827451792a6fe0e6a856268d6ab9ed 223 Pfam PF08282 haloacid dehalogenase-like hydrolase 7 96 2.1E-10 T 01-11-2018 AFULGI_00004480 2b827451792a6fe0e6a856268d6ab9ed 223 Pfam PF08282 haloacid dehalogenase-like hydrolase 136 216 5.1E-25 T 01-11-2018 AFULGI_00004480 2b827451792a6fe0e6a856268d6ab9ed 223 SUPERFAMILY SSF56784 3 217 1.29E-47 T 01-11-2018 IPR036412 HAD-like superfamily AFULGI_00004480 2b827451792a6fe0e6a856268d6ab9ed 223 Gene3D G3DSA:3.90.1070.10 81 142 3.3E-62 T 01-11-2018 AFULGI_00011180 2ea57ab5b6f2ebe3e626c217e284f4e8 127 TIGRFAM TIGR00637 ModE_repress: ModE molybdate transport repressor domain 17 113 2.3E-37 T 01-11-2018 IPR003725 Molybdenum-binding protein ModE, N-terminal AFULGI_00011180 2ea57ab5b6f2ebe3e626c217e284f4e8 127 SUPERFAMILY SSF46785 1 99 3.22E-22 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00011180 2ea57ab5b6f2ebe3e626c217e284f4e8 127 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 23 82 7.4E-11 T 01-11-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFULGI_00011180 2ea57ab5b6f2ebe3e626c217e284f4e8 127 Gene3D G3DSA:1.10.10.10 1 119 1.1E-32 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00018950 09a965d49a12e0a6271be7ba4e16cfea 401 SUPERFAMILY SSF52507 16 215 3.27E-46 T 01-11-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 AFULGI_00018950 09a965d49a12e0a6271be7ba4e16cfea 401 SUPERFAMILY SSF102645 176 396 4.58E-54 T 01-11-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 AFULGI_00018950 09a965d49a12e0a6271be7ba4e16cfea 401 Gene3D G3DSA:3.40.50.10300 185 399 6.5E-56 T 01-11-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 AFULGI_00018950 09a965d49a12e0a6271be7ba4e16cfea 401 Pfam PF02441 Flavoprotein 17 183 1.9E-38 T 01-11-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 AFULGI_00018950 09a965d49a12e0a6271be7ba4e16cfea 401 Gene3D G3DSA:3.40.50.1950 13 184 3.2E-46 T 01-11-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 AFULGI_00018950 09a965d49a12e0a6271be7ba4e16cfea 401 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 191 373 6.9E-50 T 01-11-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 AFULGI_00018950 09a965d49a12e0a6271be7ba4e16cfea 401 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 14 396 2.2E-149 T 01-11-2018 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|MetaCyc: PWY-7851 AFULGI_00010690 8654ac9f4793074455ee6b2619001162 204 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 28 194 6.3E-20 T 01-11-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFULGI_00010690 8654ac9f4793074455ee6b2619001162 204 Gene3D G3DSA:1.10.3720.10 4 196 2.1E-28 T 01-11-2018 IPR035906 MetI-like superfamily AFULGI_00010690 8654ac9f4793074455ee6b2619001162 204 SUPERFAMILY SSF161098 8 188 2.09E-34 T 01-11-2018 IPR035906 MetI-like superfamily AFULGI_00014240 fb5bc873357c31b3933fc4bba0b77be9 215 SUPERFAMILY SSF51905 3 38 4.86E-5 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFULGI_00014240 fb5bc873357c31b3933fc4bba0b77be9 215 Gene3D G3DSA:3.40.50.720 3 58 4.4E-5 T 01-11-2018 AFULGI_00013790 ad9fd889bc8d4b3690b35308ae55cba8 154 SUPERFAMILY SSF52255 3 153 1.57E-37 T 01-11-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 AFULGI_00013790 ad9fd889bc8d4b3690b35308ae55cba8 154 Hamap MF_02045 Phosphoribosylaminoimidazole carboxylase [purE]. 1 154 37.416 T 01-11-2018 IPR033626 Class II PurE GO:0006189 KEGG: 00230+4.1.1.21|MetaCyc: PWY-6124|Reactome: R-HSA-73817 AFULGI_00013790 ad9fd889bc8d4b3690b35308ae55cba8 154 Gene3D G3DSA:3.40.50.7700 1 154 2.4E-53 T 01-11-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 AFULGI_00013790 ad9fd889bc8d4b3690b35308ae55cba8 154 PIRSF PIRSF001338 1 154 2.2E-57 T 01-11-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 AFULGI_00013790 ad9fd889bc8d4b3690b35308ae55cba8 154 Pfam PF00731 AIR carboxylase 4 144 8.7E-41 T 01-11-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 AFULGI_00013790 ad9fd889bc8d4b3690b35308ae55cba8 154 SMART SM01001 1 146 9.3E-45 T 01-11-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 AFULGI_00013790 ad9fd889bc8d4b3690b35308ae55cba8 154 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 4 153 1.5E-49 T 01-11-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 AFULGI_00005360 8a79fc94f4e6b5ccc21e3a376e6b6412 267 SUPERFAMILY SSF116742 90 178 2.09E-22 T 01-11-2018 IPR024054 Translation initiation factor 2, alpha subunit, middle domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 AFULGI_00005360 8a79fc94f4e6b5ccc21e3a376e6b6412 267 SUPERFAMILY SSF50249 15 102 8.92E-23 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold AFULGI_00005360 8a79fc94f4e6b5ccc21e3a376e6b6412 267 Gene3D G3DSA:1.10.150.190 90 177 1.2E-24 T 01-11-2018 IPR024054 Translation initiation factor 2, alpha subunit, middle domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 AFULGI_00005360 8a79fc94f4e6b5ccc21e3a376e6b6412 267 Gene3D G3DSA:3.30.70.1130 178 264 9.3E-30 T 01-11-2018 IPR024055 Translation initiation factor 2, alpha subunit, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 AFULGI_00005360 8a79fc94f4e6b5ccc21e3a376e6b6412 267 SUPERFAMILY SSF110993 180 262 1.96E-25 T 01-11-2018 IPR024055 Translation initiation factor 2, alpha subunit, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 AFULGI_00005360 8a79fc94f4e6b5ccc21e3a376e6b6412 267 Gene3D G3DSA:2.40.50.140 4 89 4.3E-31 T 01-11-2018 AFULGI_00005360 8a79fc94f4e6b5ccc21e3a376e6b6412 267 Hamap MF_00231 Translation initiation factor 2 subunit alpha [eif2a]. 8 265 34.914 T 01-11-2018 IPR022964 Translation initiation factor 2, alpha subunit, archaeal AFULGI_00005360 8a79fc94f4e6b5ccc21e3a376e6b6412 267 Pfam PF00575 S1 RNA binding domain 14 88 9.7E-17 T 01-11-2018 IPR003029 S1 domain GO:0003676 AFULGI_00005360 8a79fc94f4e6b5ccc21e3a376e6b6412 267 SMART SM00316 15 88 1.5E-25 T 01-11-2018 IPR022967 RNA-binding domain, S1 AFULGI_00005360 8a79fc94f4e6b5ccc21e3a376e6b6412 267 Pfam PF07541 Eukaryotic translation initiation factor 2 alpha subunit 127 235 8.2E-25 T 01-11-2018 IPR011488 Translation initiation factor 2, alpha subunit GO:0003723|GO:0003743 Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 AFULGI_00014030 195c9f2002cff69d0b3176e3d9d27332 382 Gene3D G3DSA:2.40.110.10 121 233 1.4E-41 T 01-11-2018 AFULGI_00014030 195c9f2002cff69d0b3176e3d9d27332 382 PIRSF PIRSF016578 4 381 1.8E-15 T 01-11-2018 AFULGI_00014030 195c9f2002cff69d0b3176e3d9d27332 382 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 335 354 - T 01-11-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 AFULGI_00014030 195c9f2002cff69d0b3176e3d9d27332 382 Gene3D G3DSA:1.20.140.10 234 381 7.1E-58 T 01-11-2018 AFULGI_00014030 195c9f2002cff69d0b3176e3d9d27332 382 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 116 2.4E-35 T 01-11-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 AFULGI_00014030 195c9f2002cff69d0b3176e3d9d27332 382 SUPERFAMILY SSF56645 1 239 1.2E-84 T 01-11-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 AFULGI_00014030 195c9f2002cff69d0b3176e3d9d27332 382 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 228 376 7.5E-55 T 01-11-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AFULGI_00014030 195c9f2002cff69d0b3176e3d9d27332 382 SUPERFAMILY SSF47203 226 380 1.32E-62 T 01-11-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 AFULGI_00014030 195c9f2002cff69d0b3176e3d9d27332 382 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 121 216 1.6E-24 T 01-11-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 AFULGI_00014030 195c9f2002cff69d0b3176e3d9d27332 382 Gene3D G3DSA:1.10.540.10 1 116 2.3E-41 T 01-11-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 AFULGI_00020820 b45048f0cfa89bef6222a9898b4db6fb 124 Gene3D G3DSA:1.20.58.1610 2 119 2.1E-9 T 01-11-2018 IPR038430 NADH:ubiquinone oxidoreductase, subunit 3 superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFULGI_00020820 b45048f0cfa89bef6222a9898b4db6fb 124 Pfam PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 23 114 5.9E-8 T 01-11-2018 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFULGI_00023990 2efa44ea2b7a1017fddd6fa77cc0e79e 379 Pfam PF00155 Aminotransferase class I and II 32 374 2.8E-66 T 01-11-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 AFULGI_00023990 2efa44ea2b7a1017fddd6fa77cc0e79e 379 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 230 243 - T 01-11-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 AFULGI_00023990 2efa44ea2b7a1017fddd6fa77cc0e79e 379 Gene3D G3DSA:3.90.1150.10 25 373 7.2E-127 T 01-11-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFULGI_00023990 2efa44ea2b7a1017fddd6fa77cc0e79e 379 Gene3D G3DSA:3.40.640.10 64 280 7.2E-127 T 01-11-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFULGI_00023990 2efa44ea2b7a1017fddd6fa77cc0e79e 379 SUPERFAMILY SSF53383 6 378 6.38E-114 T 01-11-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFULGI_00015260 17d8df8a603fe789bcd14d1ea2e567ff 381 SMART SM00722 48 193 3.0E-6 T 01-11-2018 IPR006633 Carbohydrate-binding/sugar hydrolysis domain AFULGI_00015260 17d8df8a603fe789bcd14d1ea2e567ff 381 Gene3D G3DSA:2.160.20.10 27 302 6.4E-13 T 01-11-2018 IPR012334 Pectin lyase fold AFULGI_00015260 17d8df8a603fe789bcd14d1ea2e567ff 381 Pfam PF05048 Periplasmic copper-binding protein (NosD) 81 208 1.2E-8 T 01-11-2018 IPR007742 Periplasmic copper-binding protein NosD, beta helix domain Reactome: R-HSA-8951664|Reactome: R-HSA-983168 AFULGI_00015260 17d8df8a603fe789bcd14d1ea2e567ff 381 SUPERFAMILY SSF51126 19 280 1.24E-27 T 01-11-2018 IPR011050 Pectin lyase fold/virulence factor AFULGI_00004560 f9ae0c3fc857d7029689f23ec9d6a174 329 SUPERFAMILY SSF55785 8 111 1.93E-20 T 01-11-2018 IPR035965 PAS domain superfamily AFULGI_00004560 f9ae0c3fc857d7029689f23ec9d6a174 329 Gene3D G3DSA:1.10.287.130 132 186 8.4E-31 T 01-11-2018 AFULGI_00004560 f9ae0c3fc857d7029689f23ec9d6a174 329 SUPERFAMILY SSF55874 191 323 6.94E-28 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFULGI_00004560 f9ae0c3fc857d7029689f23ec9d6a174 329 SMART SM00091 6 72 3.3E-12 T 01-11-2018 IPR000014 PAS domain AFULGI_00004560 f9ae0c3fc857d7029689f23ec9d6a174 329 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 224 324 4.4E-19 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFULGI_00004560 f9ae0c3fc857d7029689f23ec9d6a174 329 PRINTS PR00344 Bacterial sensor protein C-terminal signature 287 305 1.1E-7 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFULGI_00004560 f9ae0c3fc857d7029689f23ec9d6a174 329 PRINTS PR00344 Bacterial sensor protein C-terminal signature 257 271 1.1E-7 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFULGI_00004560 f9ae0c3fc857d7029689f23ec9d6a174 329 PRINTS PR00344 Bacterial sensor protein C-terminal signature 311 324 1.1E-7 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFULGI_00004560 f9ae0c3fc857d7029689f23ec9d6a174 329 SMART SM00387 221 327 5.7E-28 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFULGI_00004560 f9ae0c3fc857d7029689f23ec9d6a174 329 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 5 121 1.6E-19 T 01-11-2018 IPR000014 PAS domain AFULGI_00004560 f9ae0c3fc857d7029689f23ec9d6a174 329 Pfam PF00989 PAS fold 8 110 9.7E-15 T 01-11-2018 IPR013767 PAS fold GO:0006355 AFULGI_00004560 f9ae0c3fc857d7029689f23ec9d6a174 329 Gene3D G3DSA:3.30.450.20 3 127 2.6E-18 T 01-11-2018 AFULGI_00004560 f9ae0c3fc857d7029689f23ec9d6a174 329 Gene3D G3DSA:3.30.565.10 188 323 8.4E-31 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFULGI_00011340 3af3d2413610492d3d5b151924ec9878 157 Hamap MF_01440 Chemoreceptor glutamine deamidase CheD [cheD]. 1 153 28.681 T 01-11-2018 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 AFULGI_00011340 3af3d2413610492d3d5b151924ec9878 157 Pfam PF03975 CheD chemotactic sensory transduction 47 148 2.8E-34 T 01-11-2018 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 AFULGI_00011340 3af3d2413610492d3d5b151924ec9878 157 SUPERFAMILY SSF64438 4 155 3.39E-48 T 01-11-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic AFULGI_00011340 3af3d2413610492d3d5b151924ec9878 157 Gene3D G3DSA:3.30.1330.200 3 155 4.6E-52 T 01-11-2018 IPR038592 CheD-like superfamily AFULGI_00011130 a83e31c8fc97ad38e897ff64854d3e17 374 Pfam PF02687 FtsX-like permease family 275 367 2.4E-13 T 01-11-2018 IPR003838 ABC transporter permease protein domain GO:0016020 AFULGI_00011130 a83e31c8fc97ad38e897ff64854d3e17 374 Pfam PF12704 MacB-like periplasmic core domain 17 215 1.9E-24 T 01-11-2018 IPR025857 MacB-like periplasmic core domain AFULGI_00009910 73e90eb29ecd91f96a1aa548935da8d3 124 Hamap MF_01095 UPF0292 protein . 1 121 33.003 T 01-11-2018 IPR022972 Uncharacterised protein family UPF0292 AFULGI_00009910 73e90eb29ecd91f96a1aa548935da8d3 124 Gene3D G3DSA:3.40.1360.10 2 117 9.4E-20 T 01-11-2018 AFULGI_00009910 73e90eb29ecd91f96a1aa548935da8d3 124 Pfam PF01751 Toprim domain 23 97 1.2E-5 T 01-11-2018 IPR006171 TOPRIM domain AFULGI_00009910 73e90eb29ecd91f96a1aa548935da8d3 124 SUPERFAMILY SSF110455 22 87 1.28E-9 T 01-11-2018 AFULGI_00009910 73e90eb29ecd91f96a1aa548935da8d3 124 SMART SM00493 21 88 7.4E-11 T 01-11-2018 IPR006171 TOPRIM domain AFULGI_00021690 0dcaa0e703e91826055d4974df74d2bf 129 Gene3D G3DSA:3.30.1490.10 69 127 3.0E-26 T 01-11-2018 AFULGI_00021690 0dcaa0e703e91826055d4974df74d2bf 129 Hamap MF_01302_A 30S ribosomal protein S8 [rpsH]. 1 129 37.423 T 01-11-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00021690 0dcaa0e703e91826055d4974df74d2bf 129 Pfam PF00410 Ribosomal protein S8 4 129 1.1E-29 T 01-11-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00021690 0dcaa0e703e91826055d4974df74d2bf 129 Gene3D G3DSA:3.30.1370.30 1 68 4.8E-29 T 01-11-2018 AFULGI_00021690 0dcaa0e703e91826055d4974df74d2bf 129 ProSitePatterns PS00053 Ribosomal protein S8 signature. 99 116 - T 01-11-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00021690 0dcaa0e703e91826055d4974df74d2bf 129 SUPERFAMILY SSF56047 1 129 1.44E-38 T 01-11-2018 IPR035987 Ribosomal protein S8 superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00018090 c928658969a1251cab27b26bd4b5dc5e 267 Pfam PF06508 Queuosine biosynthesis protein QueC 21 84 4.3E-9 T 01-11-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 AFULGI_00018090 c928658969a1251cab27b26bd4b5dc5e 267 SUPERFAMILY SSF52402 20 217 1.5E-35 T 01-11-2018 AFULGI_00018090 c928658969a1251cab27b26bd4b5dc5e 267 Gene3D G3DSA:3.40.50.620 5 243 1.5E-27 T 01-11-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFULGI_00018090 c928658969a1251cab27b26bd4b5dc5e 267 TIGRFAM TIGR00268 TIGR00268: TIGR00268 family protein 8 262 3.3E-128 T 01-11-2018 IPR005232 Pyridinium-3,5-bisthiocarboxylic acid mononucleotide synthase LarE GO:0016783 AFULGI_00018090 c928658969a1251cab27b26bd4b5dc5e 267 PIRSF PIRSF006661 2 266 1.7E-106 T 01-11-2018 IPR005232 Pyridinium-3,5-bisthiocarboxylic acid mononucleotide synthase LarE GO:0016783 AFULGI_00004050 565aa905c35ac74762fdf7aac9007036 284 SUPERFAMILY SSF53613 8 267 2.03E-54 T 01-11-2018 IPR029056 Ribokinase-like AFULGI_00004050 565aa905c35ac74762fdf7aac9007036 284 Gene3D G3DSA:3.40.1190.20 6 282 1.6E-61 T 01-11-2018 IPR029056 Ribokinase-like AFULGI_00004050 565aa905c35ac74762fdf7aac9007036 284 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 36 60 - T 01-11-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 AFULGI_00004050 565aa905c35ac74762fdf7aac9007036 284 Pfam PF00294 pfkB family carbohydrate kinase 29 268 2.3E-40 T 01-11-2018 IPR011611 Carbohydrate kinase PfkB AFULGI_00004050 565aa905c35ac74762fdf7aac9007036 284 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 224 237 - T 01-11-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 AFULGI_00004740 590183c7b7829acff0c0dfd7d87c88e4 684 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 122 422 3.4E-55 T 01-11-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit AFULGI_00004740 590183c7b7829acff0c0dfd7d87c88e4 684 TIGRFAM TIGR02123 TRAP_fused: TRAP transporter, 4TM/12TM fusion protein 25 681 1.8E-214 T 01-11-2018 IPR011853 TRAP C4-dicarboxylate transport system permease, fused DctM-DctQ AFULGI_00004400 ba7f016f18c725d0d2549750f12b2e3c 382 Gene3D G3DSA:1.20.140.10 236 381 7.2E-58 T 01-11-2018 AFULGI_00004400 ba7f016f18c725d0d2549750f12b2e3c 382 SUPERFAMILY SSF47203 228 381 7.57E-62 T 01-11-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 AFULGI_00004400 ba7f016f18c725d0d2549750f12b2e3c 382 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 113 8.0E-29 T 01-11-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 AFULGI_00004400 ba7f016f18c725d0d2549750f12b2e3c 382 SUPERFAMILY SSF56645 1 242 1.44E-75 T 01-11-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 AFULGI_00004400 ba7f016f18c725d0d2549750f12b2e3c 382 Gene3D G3DSA:2.40.110.10 121 235 9.4E-42 T 01-11-2018 AFULGI_00004400 ba7f016f18c725d0d2549750f12b2e3c 382 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 218 5.0E-27 T 01-11-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 AFULGI_00004400 ba7f016f18c725d0d2549750f12b2e3c 382 Gene3D G3DSA:1.10.540.10 1 119 1.7E-37 T 01-11-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 AFULGI_00004400 ba7f016f18c725d0d2549750f12b2e3c 382 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 230 378 7.3E-56 T 01-11-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AFULGI_00004400 ba7f016f18c725d0d2549750f12b2e3c 382 PIRSF PIRSF016578 4 381 2.2E-21 T 01-11-2018 AFULGI_00004400 ba7f016f18c725d0d2549750f12b2e3c 382 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 337 356 - T 01-11-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 AFULGI_00023200 5d753fe173a3855d0d31f19a716eb278 278 SUPERFAMILY SSF52518 4 274 3.3E-65 T 01-11-2018 IPR029061 Thiamin diphosphate-binding fold AFULGI_00023200 5d753fe173a3855d0d31f19a716eb278 278 Gene3D G3DSA:3.40.50.970 57 276 1.3E-55 T 01-11-2018 AFULGI_00023200 5d753fe173a3855d0d31f19a716eb278 278 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 33 188 3.4E-20 T 01-11-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 AFULGI_00026820 9e2a0fa98b256ba0cacacb8b6c8353e7 122 Gene3D G3DSA:1.10.12.20 4 46 6.5E-6 T 01-11-2018 AFULGI_00026820 9e2a0fa98b256ba0cacacb8b6c8353e7 122 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 8 40 4.3E-10 T 01-11-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal AFULGI_00026820 9e2a0fa98b256ba0cacacb8b6c8353e7 122 SUPERFAMILY SSF50249 4 106 1.25E-26 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold AFULGI_00026820 9e2a0fa98b256ba0cacacb8b6c8353e7 122 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 46 101 1.4E-15 T 01-11-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal AFULGI_00014500 161264b8a90f40a937a88db2441db87f 464 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 247 426 2.4E-47 T 01-11-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 AFULGI_00014500 161264b8a90f40a937a88db2441db87f 464 Gene3D G3DSA:3.40.50.880 247 412 1.2E-13 T 01-11-2018 IPR029062 Class I glutamine amidotransferase-like AFULGI_00014500 161264b8a90f40a937a88db2441db87f 464 SUPERFAMILY SSF52317 191 420 2.62E-24 T 01-11-2018 IPR029062 Class I glutamine amidotransferase-like AFULGI_00014500 161264b8a90f40a937a88db2441db87f 464 TIGRFAM TIGR00313 cobQ: cobyric acid synthase CobQ 4 462 3.5E-219 T 01-11-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 AFULGI_00014500 161264b8a90f40a937a88db2441db87f 464 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 5 228 5.7E-22 T 01-11-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain AFULGI_00014500 161264b8a90f40a937a88db2441db87f 464 SUPERFAMILY SSF52540 1 229 9.35E-50 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00014500 161264b8a90f40a937a88db2441db87f 464 Hamap MF_00028 Cobyric acid synthase [cobQ]. 1 464 141.549 T 01-11-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 AFULGI_00014500 161264b8a90f40a937a88db2441db87f 464 Gene3D G3DSA:3.40.50.300 3 238 2.5E-49 T 01-11-2018 AFULGI_00022230 18181f8c0126f995f4e864f3b825b458 418 Gene3D G3DSA:3.30.499.10 271 418 7.0E-57 T 01-11-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 AFULGI_00022230 18181f8c0126f995f4e864f3b825b458 418 TIGRFAM TIGR01343 hacA_fam: homoaconitate hydratase family protein 4 415 5.2E-178 T 01-11-2018 IPR006251 Homoaconitase/3-isopropylmalate dehydratase, large subunit GO:0008652|GO:0016836|GO:0051539 KEGG: 00290+4.2.1.33 AFULGI_00022230 18181f8c0126f995f4e864f3b825b458 418 ProSitePatterns PS01244 Aconitase family signature 2. 350 363 - T 01-11-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 AFULGI_00022230 18181f8c0126f995f4e864f3b825b458 418 Gene3D G3DSA:3.30.499.20 4 268 1.9E-98 T 01-11-2018 AFULGI_00022230 18181f8c0126f995f4e864f3b825b458 418 Hamap MF_01027 3-isopropylmalate dehydratase large subunit [leuC]. 3 417 51.846 T 01-11-2018 IPR011826 Homoaconitase/3-isopropylmalate dehydratase, large subunit, prokaryotic GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 AFULGI_00022230 18181f8c0126f995f4e864f3b825b458 418 PRINTS PR00415 Aconitase family signature 126 141 2.9E-14 T 01-11-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 AFULGI_00022230 18181f8c0126f995f4e864f3b825b458 418 PRINTS PR00415 Aconitase family signature 294 305 2.9E-14 T 01-11-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 AFULGI_00022230 18181f8c0126f995f4e864f3b825b458 418 PRINTS PR00415 Aconitase family signature 350 363 2.9E-14 T 01-11-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 AFULGI_00022230 18181f8c0126f995f4e864f3b825b458 418 PRINTS PR00415 Aconitase family signature 112 125 2.9E-14 T 01-11-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 AFULGI_00022230 18181f8c0126f995f4e864f3b825b458 418 SUPERFAMILY SSF53732 2 417 1.31E-143 T 01-11-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 AFULGI_00022230 18181f8c0126f995f4e864f3b825b458 418 TIGRFAM TIGR02086 IPMI_arch: 3-isopropylmalate dehydratase, large subunit 3 415 5.4E-173 T 01-11-2018 IPR011826 Homoaconitase/3-isopropylmalate dehydratase, large subunit, prokaryotic GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 AFULGI_00022230 18181f8c0126f995f4e864f3b825b458 418 Pfam PF00330 Aconitase family (aconitate hydratase) 8 409 3.4E-96 T 01-11-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 AFULGI_00022230 18181f8c0126f995f4e864f3b825b458 418 ProSitePatterns PS00450 Aconitase family signature 1. 290 306 - T 01-11-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 AFULGI_00017610 3140efc1dcdb69df9ad07bc38808b10f 262 SMART SM00849 32 225 4.2E-21 T 01-11-2018 IPR001279 Metallo-beta-lactamase AFULGI_00017610 3140efc1dcdb69df9ad07bc38808b10f 262 SUPERFAMILY SSF56281 12 256 6.42E-34 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFULGI_00017610 3140efc1dcdb69df9ad07bc38808b10f 262 Gene3D G3DSA:3.60.15.10 1 215 2.7E-50 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFULGI_00017610 3140efc1dcdb69df9ad07bc38808b10f 262 Pfam PF00753 Metallo-beta-lactamase superfamily 31 235 4.6E-24 T 01-11-2018 IPR001279 Metallo-beta-lactamase AFULGI_00020230 feac166753314bc46fe6ed52072c1bae 569 SUPERFAMILY SSF56801 23 565 9.03E-171 T 01-11-2018 AFULGI_00020230 feac166753314bc46fe6ed52072c1bae 569 Gene3D G3DSA:3.30.300.310 463 567 4.9E-37 T 01-11-2018 AFULGI_00020230 feac166753314bc46fe6ed52072c1bae 569 ProSitePatterns PS00455 Putative AMP-binding domain signature. 220 231 - T 01-11-2018 IPR020845 AMP-binding, conserved site AFULGI_00020230 feac166753314bc46fe6ed52072c1bae 569 Pfam PF13193 AMP-binding enzyme C-terminal domain 476 553 6.6E-23 T 01-11-2018 IPR025110 AMP-binding enzyme, C-terminal domain AFULGI_00020230 feac166753314bc46fe6ed52072c1bae 569 Pfam PF00501 AMP-binding enzyme 44 466 8.0E-119 T 01-11-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFULGI_00020230 feac166753314bc46fe6ed52072c1bae 569 Gene3D G3DSA:3.40.50.12780 35 460 1.5E-126 T 01-11-2018 AFULGI_00004870 0b4de0e1599617ee85a981b8983a8407 315 TIGRFAM TIGR03123 one_C_unchar_1: probable H4MPT-linked C1 transfer pathway protein 4 312 2.1E-122 T 01-11-2018 IPR002756 4-[[4-(2-aminoethyl)phenoxy]-methyl]-2-furanmethanamine-glutamate synthase KEGG: 00680+2.5.1.131|MetaCyc: PWY-5254 AFULGI_00004870 0b4de0e1599617ee85a981b8983a8407 315 Pfam PF01968 Hydantoinase/oxoprolinase 53 297 1.8E-23 T 01-11-2018 IPR002821 Hydantoinase A/oxoprolinase GO:0016787 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 AFULGI_00004870 0b4de0e1599617ee85a981b8983a8407 315 Gene3D G3DSA:3.30.420.190 106 315 8.6E-65 T 01-11-2018 AFULGI_00004870 0b4de0e1599617ee85a981b8983a8407 315 Gene3D G3DSA:3.30.420.40 3 105 2.5E-24 T 01-11-2018 AFULGI_00020300 a9cb20c821af871055462b2083621d22 323 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 112 290 5.5E-62 T 01-11-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 AFULGI_00020300 a9cb20c821af871055462b2083621d22 323 SUPERFAMILY SSF52283 23 137 8.69E-28 T 01-11-2018 AFULGI_00020300 a9cb20c821af871055462b2083621d22 323 Gene3D G3DSA:3.40.50.720 101 291 8.6E-101 T 01-11-2018 AFULGI_00020300 a9cb20c821af871055462b2083621d22 323 SUPERFAMILY SSF51735 103 291 9.72E-59 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily AFULGI_00020300 a9cb20c821af871055462b2083621d22 323 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 25 321 1.9E-30 T 01-11-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 AFULGI_00020300 a9cb20c821af871055462b2083621d22 323 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 228 244 - T 01-11-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site AFULGI_00020300 a9cb20c821af871055462b2083621d22 323 Gene3D G3DSA:3.40.50.720 25 316 8.6E-101 T 01-11-2018 AFULGI_00020300 a9cb20c821af871055462b2083621d22 323 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 199 221 - T 01-11-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site AFULGI_00001380 e554a8fce375a58d375b091384db1178 261 SUPERFAMILY SSF53335 24 220 1.03E-41 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFULGI_00001380 e554a8fce375a58d375b091384db1178 261 Gene3D G3DSA:3.40.50.150 29 219 8.6E-42 T 01-11-2018 AFULGI_00001380 e554a8fce375a58d375b091384db1178 261 Pfam PF08241 Methyltransferase domain 65 157 4.5E-25 T 01-11-2018 IPR013216 Methyltransferase type 11 GO:0008168 AFULGI_00011830 a90739cca12cd202fbb612870a7577f5 60 Gene3D G3DSA:4.10.1150.10 1 59 3.7E-19 T 01-11-2018 IPR024069 AF2212-like domain superfamily AFULGI_00011830 a90739cca12cd202fbb612870a7577f5 60 Pfam PF01954 Protein of unknown function DUF104 1 56 2.3E-22 T 01-11-2018 IPR008203 Uncharacterised protein family UPF0165 AFULGI_00011830 a90739cca12cd202fbb612870a7577f5 60 SUPERFAMILY SSF141694 1 58 1.1E-16 T 01-11-2018 AFULGI_00018620 1ddb2a438c80a4c352a62f5e8be38e41 340 Hamap MF_01947 N(4)-bis(aminopropyl)spermidine synthase [bpsA]. 1 338 40.977 T 01-11-2018 IPR014435 N(4)-bis(aminopropyl)spermidine synthase GO:0006596|GO:0016765 AFULGI_00018620 1ddb2a438c80a4c352a62f5e8be38e41 340 Gene3D G3DSA:3.40.50.150 88 312 2.1E-70 T 01-11-2018 AFULGI_00018620 1ddb2a438c80a4c352a62f5e8be38e41 340 PIRSF PIRSF005895 1 340 7.9E-145 T 01-11-2018 IPR014435 N(4)-bis(aminopropyl)spermidine synthase GO:0006596|GO:0016765 AFULGI_00018620 1ddb2a438c80a4c352a62f5e8be38e41 340 SUPERFAMILY SSF46785 6 66 1.52E-8 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00018620 1ddb2a438c80a4c352a62f5e8be38e41 340 SUPERFAMILY SSF53335 147 230 9.88E-8 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFULGI_00018620 1ddb2a438c80a4c352a62f5e8be38e41 340 Pfam PF01861 Protein of unknown function DUF43 92 336 1.0E-111 T 01-11-2018 IPR002723 N(4)-bis(aminopropyl)spermidine synthase, C-terminal AFULGI_00018620 1ddb2a438c80a4c352a62f5e8be38e41 340 Gene3D G3DSA:1.10.10.10 2 72 3.1E-7 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00006320 2fdad6116f66f31816f842f7e21a1a0b 262 Pfam PF10040 CRISPR-associated endoribonuclease Cas6 133 253 7.2E-14 T 01-11-2018 IPR019267 CRISPR-associated protein Cas6, C-terminal AFULGI_00006320 2fdad6116f66f31816f842f7e21a1a0b 262 Gene3D G3DSA:3.30.70.1900 124 257 2.6E-27 T 01-11-2018 AFULGI_00006320 2fdad6116f66f31816f842f7e21a1a0b 262 TIGRFAM TIGR01877 cas_cas6: CRISPR-associated endoribonuclease Cas6 46 254 1.7E-19 T 01-11-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 AFULGI_00006320 2fdad6116f66f31816f842f7e21a1a0b 262 Gene3D G3DSA:3.30.70.1890 7 118 3.7E-8 T 01-11-2018 AFULGI_00018420 627f299a3030ba7ef54184522deb49dd 230 Pfam PF13241 Putative NAD(P)-binding 5 117 4.5E-21 T 01-11-2018 AFULGI_00018420 627f299a3030ba7ef54184522deb49dd 230 SUPERFAMILY SSF51735 3 109 4.53E-21 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily AFULGI_00018420 627f299a3030ba7ef54184522deb49dd 230 TIGRFAM TIGR01470 cysG_Nterm: siroheme synthase, N-terminal domain 3 210 3.0E-19 T 01-11-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 AFULGI_00018420 627f299a3030ba7ef54184522deb49dd 230 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 14 41 - T 01-11-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 AFULGI_00018420 627f299a3030ba7ef54184522deb49dd 230 SUPERFAMILY SSF75615 123 215 3.92E-6 T 01-11-2018 AFULGI_00018420 627f299a3030ba7ef54184522deb49dd 230 Gene3D G3DSA:3.40.50.720 3 133 6.4E-25 T 01-11-2018 AFULGI_00025560 677f03da4f70ddb54acc4e5feee6beb3 298 Pfam PF08608 Wyosine base formation 236 296 2.0E-21 T 01-11-2018 IPR013917 tRNA wybutosine-synthesis MetaCyc: PWY-7285|MetaCyc: PWY-7286 AFULGI_00025560 677f03da4f70ddb54acc4e5feee6beb3 298 Pfam PF04055 Radical SAM superfamily 56 227 1.5E-24 T 01-11-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFULGI_00025560 677f03da4f70ddb54acc4e5feee6beb3 298 TIGRFAM TIGR03972 rSAM_TYW1: wyosine biosynthesis protein TYW1 10 295 1.9E-125 T 01-11-2018 IPR023993 S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, archaea GO:0008033|GO:0016829|GO:0051539 MetaCyc: PWY-7285|MetaCyc: PWY-7286 AFULGI_00025560 677f03da4f70ddb54acc4e5feee6beb3 298 Hamap MF_01921 S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase [taw1]. 4 296 47.743 T 01-11-2018 IPR023993 S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, archaea GO:0008033|GO:0016829|GO:0051539 MetaCyc: PWY-7285|MetaCyc: PWY-7286 AFULGI_00025560 677f03da4f70ddb54acc4e5feee6beb3 298 Gene3D G3DSA:3.20.20.70 1 298 1.7E-112 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFULGI_00025560 677f03da4f70ddb54acc4e5feee6beb3 298 SUPERFAMILY SSF102114 55 250 5.62E-20 T 01-11-2018 AFULGI_00022200 24e2fd3a5eda3de56b7198af4db01c8a 333 Pfam PF13353 4Fe-4S single cluster domain 125 212 1.1E-5 T 01-11-2018 AFULGI_00022200 24e2fd3a5eda3de56b7198af4db01c8a 333 Pfam PF04055 Radical SAM superfamily 126 269 1.5E-14 T 01-11-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFULGI_00022200 24e2fd3a5eda3de56b7198af4db01c8a 333 PIRSF PIRSF004869 23 333 8.8E-64 T 01-11-2018 IPR016431 Pyruvate-formate lyase-activating enzyme, predicted AFULGI_00022200 24e2fd3a5eda3de56b7198af4db01c8a 333 SUPERFAMILY SSF102114 127 327 1.31E-21 T 01-11-2018 AFULGI_00022200 24e2fd3a5eda3de56b7198af4db01c8a 333 Gene3D G3DSA:3.20.20.70 121 332 4.2E-15 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFULGI_00015340 fc62f2e466b2b98252b7873ab181bffa 249 Gene3D G3DSA:3.30.479.30 46 177 7.8E-53 T 01-11-2018 AFULGI_00015340 fc62f2e466b2b98252b7873ab181bffa 249 PRINTS PR00721 Stomatin signature 170 191 1.5E-73 T 01-11-2018 IPR001972 Stomatin family GO:0016020 AFULGI_00015340 fc62f2e466b2b98252b7873ab181bffa 249 PRINTS PR00721 Stomatin signature 127 150 1.5E-73 T 01-11-2018 IPR001972 Stomatin family GO:0016020 AFULGI_00015340 fc62f2e466b2b98252b7873ab181bffa 249 PRINTS PR00721 Stomatin signature 72 93 1.5E-73 T 01-11-2018 IPR001972 Stomatin family GO:0016020 AFULGI_00015340 fc62f2e466b2b98252b7873ab181bffa 249 PRINTS PR00721 Stomatin signature 25 47 1.5E-73 T 01-11-2018 IPR001972 Stomatin family GO:0016020 AFULGI_00015340 fc62f2e466b2b98252b7873ab181bffa 249 PRINTS PR00721 Stomatin signature 107 124 1.5E-73 T 01-11-2018 IPR001972 Stomatin family GO:0016020 AFULGI_00015340 fc62f2e466b2b98252b7873ab181bffa 249 PRINTS PR00721 Stomatin signature 195 218 1.5E-73 T 01-11-2018 IPR001972 Stomatin family GO:0016020 AFULGI_00015340 fc62f2e466b2b98252b7873ab181bffa 249 PRINTS PR00721 Stomatin signature 151 169 1.5E-73 T 01-11-2018 IPR001972 Stomatin family GO:0016020 AFULGI_00015340 fc62f2e466b2b98252b7873ab181bffa 249 ProSitePatterns PS01270 Band 7 protein family signature. 131 159 - T 01-11-2018 IPR018080 Band 7/stomatin-like, conserved site AFULGI_00015340 fc62f2e466b2b98252b7873ab181bffa 249 SUPERFAMILY SSF117892 49 182 3.79E-46 T 01-11-2018 IPR036013 Band 7/SPFH domain superfamily AFULGI_00015340 fc62f2e466b2b98252b7873ab181bffa 249 Pfam PF01145 SPFH domain / Band 7 family 22 191 1.2E-38 T 01-11-2018 IPR001107 Band 7 domain AFULGI_00015340 fc62f2e466b2b98252b7873ab181bffa 249 SMART SM00244 18 175 1.3E-73 T 01-11-2018 IPR001107 Band 7 domain AFULGI_00013150 c630ed7f50c482a60df101e040aa6943 493 Gene3D G3DSA:1.10.10.770 309 402 1.3E-14 T 01-11-2018 AFULGI_00013150 c630ed7f50c482a60df101e040aa6943 493 Gene3D G3DSA:3.40.50.620 3 261 3.1E-95 T 01-11-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFULGI_00013150 c630ed7f50c482a60df101e040aa6943 493 Gene3D G3DSA:1.10.10.860 262 308 1.4E-6 T 01-11-2018 AFULGI_00013150 c630ed7f50c482a60df101e040aa6943 493 TIGRFAM TIGR00467 lysS_arch: lysine--tRNA ligase 1 492 2.1E-255 T 01-11-2018 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 AFULGI_00013150 c630ed7f50c482a60df101e040aa6943 493 Hamap MF_00177 Lysine--tRNA ligase [lysS]. 1 493 37.905 T 01-11-2018 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 AFULGI_00013150 c630ed7f50c482a60df101e040aa6943 493 Gene3D G3DSA:2.30.30.300 162 205 3.1E-95 T 01-11-2018 IPR023386 Lysine-tRNA ligase, insertion domain superfamily GO:0004824 KEGG: 00970+6.1.1.6 AFULGI_00013150 c630ed7f50c482a60df101e040aa6943 493 Pfam PF01921 tRNA synthetases class I (K) 1 324 1.3E-126 T 01-11-2018 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 AFULGI_00013150 c630ed7f50c482a60df101e040aa6943 493 Gene3D G3DSA:1.10.10.350 403 491 5.3E-24 T 01-11-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 AFULGI_00013150 c630ed7f50c482a60df101e040aa6943 493 SUPERFAMILY SSF48163 331 493 1.03E-38 T 01-11-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 AFULGI_00013150 c630ed7f50c482a60df101e040aa6943 493 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 26 35 - T 01-11-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFULGI_00013150 c630ed7f50c482a60df101e040aa6943 493 SUPERFAMILY SSF52374 3 309 7.51E-61 T 01-11-2018 AFULGI_00015330 3e3533b1f44a53fb729466276c613267 271 Hamap MF_00583_A Putative ribose-phosphate pyrophosphokinase [prs]. 2 269 36.396 T 01-11-2018 IPR037514 Ribose-phosphate pyrophosphokinase, archaea GO:0004749 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 AFULGI_00015330 3e3533b1f44a53fb729466276c613267 271 Gene3D G3DSA:3.40.50.2020 131 254 7.0E-73 T 01-11-2018 AFULGI_00015330 3e3533b1f44a53fb729466276c613267 271 Pfam PF00156 Phosphoribosyl transferase domain 139 231 6.5E-17 T 01-11-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 AFULGI_00015330 3e3533b1f44a53fb729466276c613267 271 SUPERFAMILY SSF53271 73 255 4.38E-34 T 01-11-2018 IPR029057 Phosphoribosyltransferase-like AFULGI_00015330 3e3533b1f44a53fb729466276c613267 271 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 1 271 5.1E-90 T 01-11-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 AFULGI_00015330 3e3533b1f44a53fb729466276c613267 271 SMART SM01400 1 106 4.8E-32 T 01-11-2018 AFULGI_00015330 3e3533b1f44a53fb729466276c613267 271 Gene3D G3DSA:3.40.50.2020 12 130 7.0E-73 T 01-11-2018 AFULGI_00015330 3e3533b1f44a53fb729466276c613267 271 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 1 104 1.1E-15 T 01-11-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 AFULGI_00006050 176b05376d071631ac214e022ede68ec 224 Pfam PF02481 DNA recombination-mediator protein A 31 216 6.8E-58 T 01-11-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 AFULGI_00006050 176b05376d071631ac214e022ede68ec 224 Gene3D G3DSA:3.40.50.450 3 222 6.0E-63 T 01-11-2018 AFULGI_00006050 176b05376d071631ac214e022ede68ec 224 SUPERFAMILY SSF102405 31 217 3.01E-28 T 01-11-2018 AFULGI_00002630 2eef4e815b0333235b759f515642b84d 195 Pfam PF00578 AhpC/TSA family 6 114 6.9E-29 T 01-11-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 AFULGI_00002630 2eef4e815b0333235b759f515642b84d 195 Hamap MF_00401 Peroxiredoxin. 1 195 47.649 T 01-11-2018 IPR022915 Peroxiredoxin, TDXH subfamily GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 AFULGI_00002630 2eef4e815b0333235b759f515642b84d 195 PIRSF PIRSF000239 1 194 1.6E-70 T 01-11-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 AFULGI_00002630 2eef4e815b0333235b759f515642b84d 195 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 135 177 6.9E-12 T 01-11-2018 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 AFULGI_00002630 2eef4e815b0333235b759f515642b84d 195 Gene3D G3DSA:3.40.30.10 1 124 4.2E-40 T 01-11-2018 AFULGI_00002630 2eef4e815b0333235b759f515642b84d 195 Gene3D G3DSA:3.30.1020.10 125 195 6.9E-33 T 01-11-2018 AFULGI_00002630 2eef4e815b0333235b759f515642b84d 195 SUPERFAMILY SSF52833 3 195 5.47E-64 T 01-11-2018 IPR036249 Thioredoxin-like superfamily AFULGI_00024080 9ec5b210be88f10c69b091fc8a150e42 385 Pfam PF13740 ACT domain 5 73 3.9E-13 T 01-11-2018 AFULGI_00024080 9ec5b210be88f10c69b091fc8a150e42 385 Pfam PF13740 ACT domain 89 161 2.8E-10 T 01-11-2018 AFULGI_00024080 9ec5b210be88f10c69b091fc8a150e42 385 SUPERFAMILY SSF56784 167 376 6.67E-55 T 01-11-2018 IPR036412 HAD-like superfamily AFULGI_00024080 9ec5b210be88f10c69b091fc8a150e42 385 Gene3D G3DSA:3.30.70.260 2 82 3.5E-18 T 01-11-2018 AFULGI_00024080 9ec5b210be88f10c69b091fc8a150e42 385 Pfam PF12710 haloacid dehalogenase-like hydrolase 173 339 3.3E-24 T 01-11-2018 AFULGI_00024080 9ec5b210be88f10c69b091fc8a150e42 385 Gene3D G3DSA:3.30.70.260 84 165 2.5E-17 T 01-11-2018 AFULGI_00024080 9ec5b210be88f10c69b091fc8a150e42 385 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 172 343 5.9E-39 T 01-11-2018 AFULGI_00024080 9ec5b210be88f10c69b091fc8a150e42 385 Gene3D G3DSA:3.40.50.1000 171 363 9.3E-78 T 01-11-2018 IPR023214 HAD superfamily AFULGI_00024080 9ec5b210be88f10c69b091fc8a150e42 385 TIGRFAM TIGR00338 serB: phosphoserine phosphatase SerB 157 375 9.6E-96 T 01-11-2018 AFULGI_00024080 9ec5b210be88f10c69b091fc8a150e42 385 Gene3D G3DSA:1.10.150.210 182 242 9.3E-78 T 01-11-2018 IPR023190 Phosphoserine phosphatase, domain 2 GO:0004647|GO:0006564 KEGG: 00260+3.1.3.3|KEGG: 00680+3.1.3.3|Reactome: R-HSA-977347 AFULGI_00024080 9ec5b210be88f10c69b091fc8a150e42 385 SUPERFAMILY SSF55021 3 76 3.5E-15 T 01-11-2018 AFULGI_00024080 9ec5b210be88f10c69b091fc8a150e42 385 SUPERFAMILY SSF55021 85 167 2.26E-15 T 01-11-2018 AFULGI_00013530 c7062aaff3711cea89c9214fdfb5e12b 307 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 148 297 6.5E-59 T 01-11-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 AFULGI_00013530 c7062aaff3711cea89c9214fdfb5e12b 307 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 2 300 3.5E-146 T 01-11-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 AFULGI_00013530 c7062aaff3711cea89c9214fdfb5e12b 307 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 2 142 7.5E-53 T 01-11-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 AFULGI_00013530 c7062aaff3711cea89c9214fdfb5e12b 307 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 265 288 5.1E-29 T 01-11-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 AFULGI_00013530 c7062aaff3711cea89c9214fdfb5e12b 307 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 253 262 5.1E-29 T 01-11-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 AFULGI_00013530 c7062aaff3711cea89c9214fdfb5e12b 307 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 47 66 5.1E-29 T 01-11-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 AFULGI_00013530 c7062aaff3711cea89c9214fdfb5e12b 307 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 129 140 5.1E-29 T 01-11-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 AFULGI_00013530 c7062aaff3711cea89c9214fdfb5e12b 307 Gene3D G3DSA:3.40.50.1370 132 296 8.5E-128 T 01-11-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 AFULGI_00013530 c7062aaff3711cea89c9214fdfb5e12b 307 Gene3D G3DSA:3.40.50.1370 2 131 8.5E-128 T 01-11-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 AFULGI_00013530 c7062aaff3711cea89c9214fdfb5e12b 307 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 1 301 84.296 T 01-11-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 AFULGI_00013530 c7062aaff3711cea89c9214fdfb5e12b 307 SUPERFAMILY SSF53671 1 302 7.07E-114 T 01-11-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 AFULGI_00013530 c7062aaff3711cea89c9214fdfb5e12b 307 PRINTS PR00102 Ornithine carbamoyltransferase signature 279 290 2.3E-30 T 01-11-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 AFULGI_00013530 c7062aaff3711cea89c9214fdfb5e12b 307 PRINTS PR00102 Ornithine carbamoyltransferase signature 217 227 2.3E-30 T 01-11-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 AFULGI_00013530 c7062aaff3711cea89c9214fdfb5e12b 307 PRINTS PR00102 Ornithine carbamoyltransferase signature 45 59 2.3E-30 T 01-11-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 AFULGI_00013530 c7062aaff3711cea89c9214fdfb5e12b 307 PRINTS PR00102 Ornithine carbamoyltransferase signature 118 132 2.3E-30 T 01-11-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 AFULGI_00013530 c7062aaff3711cea89c9214fdfb5e12b 307 PRINTS PR00102 Ornithine carbamoyltransferase signature 78 91 2.3E-30 T 01-11-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 AFULGI_00005370 5de520a5bd656686ccaa738057f28de1 232 Gene3D G3DSA:3.40.50.80 84 190 3.1E-23 T 01-11-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain AFULGI_00005370 5de520a5bd656686ccaa738057f28de1 232 Hamap MF_01211 Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit [pyrK]. 1 232 33.526 T 01-11-2018 IPR023455 Dihydroorotate dehydrogenase electron transfer subunit AFULGI_00005370 5de520a5bd656686ccaa738057f28de1 232 SUPERFAMILY SSF52343 82 230 6.42E-32 T 01-11-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain AFULGI_00005370 5de520a5bd656686ccaa738057f28de1 232 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 197 230 3.2E-13 T 01-11-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain AFULGI_00005370 5de520a5bd656686ccaa738057f28de1 232 Gene3D G3DSA:2.40.30.10 1 83 4.0E-7 T 01-11-2018 AFULGI_00005370 5de520a5bd656686ccaa738057f28de1 232 SUPERFAMILY SSF63380 2 84 4.12E-15 T 01-11-2018 IPR017938 Riboflavin synthase-like beta-barrel AFULGI_00005370 5de520a5bd656686ccaa738057f28de1 232 Gene3D G3DSA:2.10.240.10 197 231 2.9E-9 T 01-11-2018 IPR037117 Dihydroorotate dehydrogenase, electron transfer subunit, Fe-S binding domain superfamily AFULGI_00005370 5de520a5bd656686ccaa738057f28de1 232 PIRSF PIRSF006816 1 232 8.0E-74 T 01-11-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 AFULGI_00005370 5de520a5bd656686ccaa738057f28de1 232 Pfam PF00175 Oxidoreductase NAD-binding domain 93 179 6.8E-8 T 01-11-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 AFULGI_00017860 e83d4c1bc7bbd8bf1d8d2f0524b90a0e 105 Gene3D G3DSA:2.30.30.240 5 77 6.3E-12 T 01-11-2018 AFULGI_00017860 e83d4c1bc7bbd8bf1d8d2f0524b90a0e 105 Pfam PF05239 PRC-barrel domain 7 76 1.5E-15 T 01-11-2018 IPR027275 PRC-barrel domain AFULGI_00017860 e83d4c1bc7bbd8bf1d8d2f0524b90a0e 105 SUPERFAMILY SSF50346 7 76 1.88E-14 T 01-11-2018 IPR011033 PRC-barrel-like superfamily AFULGI_00005010 4a7804ed0070e3e73202bb7565208eb6 258 SUPERFAMILY SSF54211 11 180 1.32E-45 T 01-11-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFULGI_00005010 4a7804ed0070e3e73202bb7565208eb6 258 Pfam PF01138 3' exoribonuclease family, domain 1 25 154 1.6E-35 T 01-11-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 AFULGI_00005010 4a7804ed0070e3e73202bb7565208eb6 258 Pfam PF03725 3' exoribonuclease family, domain 2 158 225 1.6E-15 T 01-11-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 AFULGI_00005010 4a7804ed0070e3e73202bb7565208eb6 258 TIGRFAM TIGR02065 ECX1: exosome complex exonuclease 1 11 241 6.2E-106 T 01-11-2018 IPR011807 Exosome complex component Rrp41 GO:0000178|GO:0006401|GO:0016896 AFULGI_00005010 4a7804ed0070e3e73202bb7565208eb6 258 SUPERFAMILY SSF55666 154 244 1.44E-23 T 01-11-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 AFULGI_00005010 4a7804ed0070e3e73202bb7565208eb6 258 Hamap MF_00591 Exosome complex component Rrp41 [rrp41]. 7 245 56.919 T 01-11-2018 IPR011807 Exosome complex component Rrp41 GO:0000178|GO:0006401|GO:0016896 AFULGI_00005010 4a7804ed0070e3e73202bb7565208eb6 258 Gene3D G3DSA:3.30.230.70 24 258 9.6E-82 T 01-11-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 AFULGI_00010960 9728da182df53b419cd40e50edb1d2c1 151 TIGRFAM TIGR00249 sixA: phosphohistidine phosphatase SixA 1 147 1.4E-61 T 01-11-2018 IPR004449 Phosphohistidine phosphatase SixA GO:0005737|GO:0006464|GO:0101006 AFULGI_00010960 9728da182df53b419cd40e50edb1d2c1 151 SUPERFAMILY SSF53254 1 139 5.57E-22 T 01-11-2018 IPR029033 Histidine phosphatase superfamily AFULGI_00010960 9728da182df53b419cd40e50edb1d2c1 151 Gene3D G3DSA:3.40.50.1240 1 151 3.4E-33 T 01-11-2018 IPR029033 Histidine phosphatase superfamily AFULGI_00010960 9728da182df53b419cd40e50edb1d2c1 151 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 3 77 1.8E-10 T 01-11-2018 IPR013078 Histidine phosphatase superfamily, clade-1 AFULGI_00023670 45bd3abf3604780a037cbfb8b474de65 369 Gene3D G3DSA:3.30.390.10 1 113 8.7E-14 T 01-11-2018 IPR029017 Enolase-like, N-terminal AFULGI_00023670 45bd3abf3604780a037cbfb8b474de65 369 SUPERFAMILY SSF54826 1 120 1.58E-16 T 01-11-2018 AFULGI_00023670 45bd3abf3604780a037cbfb8b474de65 369 SMART SM00922 134 237 2.1E-18 T 01-11-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal AFULGI_00023670 45bd3abf3604780a037cbfb8b474de65 369 SUPERFAMILY SSF51604 104 368 9.96E-66 T 01-11-2018 IPR036849 Enolase-like, C-terminal domain superfamily AFULGI_00023670 45bd3abf3604780a037cbfb8b474de65 369 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 12 116 2.5E-5 T 01-11-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain AFULGI_00023670 45bd3abf3604780a037cbfb8b474de65 369 Pfam PF13378 Enolase C-terminal domain-like 141 361 7.0E-58 T 01-11-2018 IPR029065 Enolase C-terminal domain-like AFULGI_00023670 45bd3abf3604780a037cbfb8b474de65 369 Gene3D G3DSA:3.20.20.120 114 369 1.5E-71 T 01-11-2018 IPR036849 Enolase-like, C-terminal domain superfamily AFULGI_00012600 740c7c1f7f88569426286436be2f0d63 676 Gene3D G3DSA:1.20.1460.20 44 270 1.4E-14 T 01-11-2018 AFULGI_00012600 740c7c1f7f88569426286436be2f0d63 676 Gene3D G3DSA:3.30.70.2750 125 205 1.4E-14 T 01-11-2018 AFULGI_00012600 740c7c1f7f88569426286436be2f0d63 676 Pfam PF01496 V-type ATPase 116kDa subunit family 160 406 8.2E-21 T 01-11-2018 IPR002490 V-type ATPase, V0 complex, 116kDa subunit family GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 AFULGI_00012600 740c7c1f7f88569426286436be2f0d63 676 Gene3D G3DSA:3.30.70.2170 7 291 1.4E-14 T 01-11-2018 AFULGI_00006630 5be9c280c2f1a1175da27034cb3c93c4 481 Gene3D G3DSA:3.20.20.105 1 354 4.9E-105 T 01-11-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 AFULGI_00006630 5be9c280c2f1a1175da27034cb3c93c4 481 SUPERFAMILY SSF51713 2 353 2.35E-105 T 01-11-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 AFULGI_00006630 5be9c280c2f1a1175da27034cb3c93c4 481 TIGRFAM TIGR00432 arcsn_tRNA_tgt: tRNA-guanine(15) transglycosylase 4 481 5.1E-258 T 01-11-2018 IPR004804 tRNA-guanine(15) transglycosylase GO:0006400|GO:0016763 MetaCyc: PWY-6711|MetaCyc: PWY-7923 AFULGI_00006630 5be9c280c2f1a1175da27034cb3c93c4 481 Hamap MF_01634 tRNA-guanine(15) transglycosylase [tgtA]. 4 481 45.248 T 01-11-2018 IPR004804 tRNA-guanine(15) transglycosylase GO:0006400|GO:0016763 MetaCyc: PWY-6711|MetaCyc: PWY-7923 AFULGI_00006630 5be9c280c2f1a1175da27034cb3c93c4 481 Pfam PF01702 Queuine tRNA-ribosyltransferase 105 328 1.5E-38 T 01-11-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 AFULGI_00006630 5be9c280c2f1a1175da27034cb3c93c4 481 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 4 336 2.1E-110 T 01-11-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 AFULGI_00006630 5be9c280c2f1a1175da27034cb3c93c4 481 SUPERFAMILY SSF88802 358 435 4.25E-10 T 01-11-2018 AFULGI_00009360 6582793dbd675232de8c89206a988433 438 Gene3D G3DSA:3.90.1150.10 288 438 1.9E-55 T 01-11-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFULGI_00009360 6582793dbd675232de8c89206a988433 438 PIRSF PIRSF000412 2 434 1.3E-159 T 01-11-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 AFULGI_00009360 6582793dbd675232de8c89206a988433 438 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 14 423 43.334 T 01-11-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 AFULGI_00009360 6582793dbd675232de8c89206a988433 438 Pfam PF00464 Serine hydroxymethyltransferase 21 395 2.6E-84 T 01-11-2018 IPR039429 Serine hydroxymethyltransferase-like domain KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 AFULGI_00009360 6582793dbd675232de8c89206a988433 438 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 231 247 - T 01-11-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 AFULGI_00009360 6582793dbd675232de8c89206a988433 438 Gene3D G3DSA:3.40.640.10 49 287 1.6E-89 T 01-11-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFULGI_00009360 6582793dbd675232de8c89206a988433 438 SUPERFAMILY SSF53383 21 422 4.66E-136 T 01-11-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFULGI_00019320 74ed0dbddba818ffc3b3c6e9849d8eca 156 Pfam PF01850 PIN domain 4 125 1.9E-12 T 01-11-2018 IPR002716 PIN domain AFULGI_00019320 74ed0dbddba818ffc3b3c6e9849d8eca 156 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 3 135 11.734 T 01-11-2018 IPR022907 VapC family GO:0004540 AFULGI_00019320 74ed0dbddba818ffc3b3c6e9849d8eca 156 SUPERFAMILY SSF88723 1 134 3.36E-21 T 01-11-2018 IPR029060 PIN-like domain superfamily AFULGI_00019320 74ed0dbddba818ffc3b3c6e9849d8eca 156 Gene3D G3DSA:3.40.50.1010 1 156 3.9E-53 T 01-11-2018 AFULGI_00001710 1d989b046ac3210731c870a169cbae57 77 SUPERFAMILY SSF64307 1 71 2.22E-22 T 01-11-2018 IPR036868 TusA-like domain superfamily AFULGI_00001710 1d989b046ac3210731c870a169cbae57 77 Gene3D G3DSA:3.30.110.40 1 74 2.4E-23 T 01-11-2018 IPR036868 TusA-like domain superfamily AFULGI_00001710 1d989b046ac3210731c870a169cbae57 77 Pfam PF01206 Sulfurtransferase TusA 2 71 2.2E-22 T 01-11-2018 IPR001455 TusA-like domain AFULGI_00001710 1d989b046ac3210731c870a169cbae57 77 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 4 28 - T 01-11-2018 IPR001455 TusA-like domain AFULGI_00012950 5507073a60f657baf2a33c6eeec91fdd 348 Hamap MF_01091 5,10-methylenetetrahydromethanopterin reductase [mer]. 1 348 104.152 T 01-11-2018 IPR019946 5,10-methylenetetrahydromethanopterin reductase GO:0018537|GO:0055114 KEGG: 00680+1.5.98.2|MetaCyc: PWY-7784 AFULGI_00012950 5507073a60f657baf2a33c6eeec91fdd 348 SUPERFAMILY SSF51679 1 344 3.79E-72 T 01-11-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFULGI_00012950 5507073a60f657baf2a33c6eeec91fdd 348 Gene3D G3DSA:3.20.20.30 1 346 1.0E-93 T 01-11-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFULGI_00012950 5507073a60f657baf2a33c6eeec91fdd 348 Pfam PF00296 Luciferase-like monooxygenase 11 319 1.1E-63 T 01-11-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 AFULGI_00015370 2ebe41799506eda7b4ebe9ccc48a4f8d 387 Pfam PF01966 HD domain 51 155 2.1E-14 T 01-11-2018 IPR006674 HD domain AFULGI_00015370 2ebe41799506eda7b4ebe9ccc48a4f8d 387 SUPERFAMILY SSF109604 2 373 5.73E-85 T 01-11-2018 AFULGI_00015370 2ebe41799506eda7b4ebe9ccc48a4f8d 387 Gene3D G3DSA:1.10.3210.10 2 264 8.7E-77 T 01-11-2018 AFULGI_00015370 2ebe41799506eda7b4ebe9ccc48a4f8d 387 SMART SM00471 47 163 1.6E-14 T 01-11-2018 IPR003607 HD/PDEase domain AFULGI_00025450 5a340d69711df0ee73e0b8464adfeca5 229 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 1 155 8.0E-39 T 01-11-2018 IPR001453 MoaB/Mog domain AFULGI_00025450 5a340d69711df0ee73e0b8464adfeca5 229 Hamap MF_00226_A Putative competence-damage inducible protein [cinA]. 1 229 39.173 T 01-11-2018 IPR023055 Putative competence-damage inducible protein, Archaea AFULGI_00025450 5a340d69711df0ee73e0b8464adfeca5 229 SUPERFAMILY SSF53218 3 189 1.83E-37 T 01-11-2018 IPR036425 MoaB/Mog-like domain superfamily AFULGI_00025450 5a340d69711df0ee73e0b8464adfeca5 229 SMART SM00852 4 161 1.6E-34 T 01-11-2018 IPR001453 MoaB/Mog domain AFULGI_00025450 5a340d69711df0ee73e0b8464adfeca5 229 Gene3D G3DSA:3.40.980.10 2 159 2.7E-48 T 01-11-2018 IPR036425 MoaB/Mog-like domain superfamily AFULGI_00025450 5a340d69711df0ee73e0b8464adfeca5 229 Pfam PF00994 Probable molybdopterin binding domain 5 157 5.6E-36 T 01-11-2018 IPR001453 MoaB/Mog domain AFULGI_00020410 748dc0efd248820b7c17bed7ccbdb241 488 Gene3D G3DSA:2.40.50.140 121 209 1.3E-5 T 01-11-2018 AFULGI_00020410 748dc0efd248820b7c17bed7ccbdb241 488 SUPERFAMILY SSF56300 224 458 7.19E-22 T 01-11-2018 AFULGI_00020410 748dc0efd248820b7c17bed7ccbdb241 488 Pfam PF00149 Calcineurin-like phosphoesterase 228 436 1.2E-15 T 01-11-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 AFULGI_00020410 748dc0efd248820b7c17bed7ccbdb241 488 PIRSF PIRSF000803 2 488 7.1E-193 T 01-11-2018 IPR011149 DNA polymerase II small subunit, archaeal GO:0003676|GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFULGI_00020410 748dc0efd248820b7c17bed7ccbdb241 488 Hamap MF_00325 DNA polymerase II small subunit [polB]. 10 484 32.714 T 01-11-2018 IPR011149 DNA polymerase II small subunit, archaeal GO:0003676|GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFULGI_00020410 748dc0efd248820b7c17bed7ccbdb241 488 Gene3D G3DSA:3.60.21.50 217 455 4.0E-26 T 01-11-2018 AFULGI_00011930 c4b91a00624aa49b1726b044c48ffef3 448 SUPERFAMILY SSF53448 1 258 1.1E-64 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFULGI_00011930 c4b91a00624aa49b1726b044c48ffef3 448 TIGRFAM TIGR01479 GMP_PMI: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase 3 446 1.2E-146 T 01-11-2018 IPR006375 Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase GO:0000271|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 AFULGI_00011930 c4b91a00624aa49b1726b044c48ffef3 448 Gene3D G3DSA:3.90.550.10 1 327 2.7E-106 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFULGI_00011930 c4b91a00624aa49b1726b044c48ffef3 448 Pfam PF01050 Mannose-6-phosphate isomerase 293 443 2.5E-69 T 01-11-2018 IPR001538 Mannose-6-phosphate isomerase, type II, C-terminal GO:0005976|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 AFULGI_00011930 c4b91a00624aa49b1726b044c48ffef3 448 SUPERFAMILY SSF51182 180 447 1.3E-60 T 01-11-2018 IPR011051 RmlC-like cupin domain superfamily AFULGI_00011930 c4b91a00624aa49b1726b044c48ffef3 448 Pfam PF00483 Nucleotidyl transferase 2 264 2.9E-62 T 01-11-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 AFULGI_00011930 c4b91a00624aa49b1726b044c48ffef3 448 Gene3D G3DSA:2.60.120.10 328 445 4.0E-19 T 01-11-2018 IPR014710 RmlC-like jelly roll fold AFULGI_00005100 5598a350aeacd4dc62cb98094f5d24ea 395 Pfam PF03916 Polysulphide reductase, NrfD 42 331 5.2E-71 T 01-11-2018 IPR005614 NrfD family AFULGI_00009970 9288ccb3e00625113f2393b5992a7d3c 65 Pfam PF00833 Ribosomal S17 1 60 1.4E-12 T 01-11-2018 IPR001210 Ribosomal protein S17e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00009970 9288ccb3e00625113f2393b5992a7d3c 65 Hamap MF_00511 30S ribosomal protein S17e [rps17e]. 1 60 20.251 T 01-11-2018 IPR001210 Ribosomal protein S17e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00009970 9288ccb3e00625113f2393b5992a7d3c 65 ProSitePatterns PS00712 Ribosomal protein S17e signature. 41 56 - T 01-11-2018 IPR018273 Ribosomal protein S17e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00009970 9288ccb3e00625113f2393b5992a7d3c 65 SUPERFAMILY SSF116820 1 59 3.01E-21 T 01-11-2018 IPR036401 Ribosomal protein S17e-like superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00009970 9288ccb3e00625113f2393b5992a7d3c 65 Gene3D G3DSA:1.10.60.20 1 61 3.9E-25 T 01-11-2018 IPR036401 Ribosomal protein S17e-like superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00008380 adea62ff4ee1c04dee9b150645007619 177 Gene3D G3DSA:1.10.10.10 6 90 8.6E-20 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00008380 adea62ff4ee1c04dee9b150645007619 177 SMART SM00531 22 160 7.2E-69 T 01-11-2018 IPR002853 Transcription initiation factor IIE subunit alpha, N-terminal GO:0006367 Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 AFULGI_00008380 adea62ff4ee1c04dee9b150645007619 177 TIGRFAM TIGR00373 TIGR00373: transcription factor E 10 170 3.4E-79 T 01-11-2018 IPR016481 Transcription factor TFE, archaea GO:0006355 AFULGI_00008380 adea62ff4ee1c04dee9b150645007619 177 SUPERFAMILY SSF46785 14 89 1.14E-17 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00008380 adea62ff4ee1c04dee9b150645007619 177 Pfam PF08271 TFIIB zinc-binding 118 159 4.0E-8 T 01-11-2018 IPR013137 Zinc finger, TFIIB-type AFULGI_00008380 adea62ff4ee1c04dee9b150645007619 177 Pfam PF02002 TFIIE alpha subunit 11 113 1.0E-37 T 01-11-2018 IPR024550 TFIIEalpha/SarR/Rpc3 HTH domain Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 AFULGI_00008380 adea62ff4ee1c04dee9b150645007619 177 PIRSF PIRSF006373 2 176 2.8E-59 T 01-11-2018 IPR016481 Transcription factor TFE, archaea GO:0006355 AFULGI_00008380 adea62ff4ee1c04dee9b150645007619 177 Hamap MF_01909 Transcription factor E [tfe]. 7 170 25.111 T 01-11-2018 IPR016481 Transcription factor TFE, archaea GO:0006355 AFULGI_00015840 55b10991bc09f7d679546cd1831bf60f 1099 Gene3D G3DSA:2.60.40.10 366 448 1.2E-14 T 01-11-2018 IPR013783 Immunoglobulin-like fold AFULGI_00015840 55b10991bc09f7d679546cd1831bf60f 1099 Gene3D G3DSA:2.60.40.10 451 525 2.7E-12 T 01-11-2018 IPR013783 Immunoglobulin-like fold AFULGI_00015840 55b10991bc09f7d679546cd1831bf60f 1099 Gene3D G3DSA:2.60.40.10 276 365 6.5E-11 T 01-11-2018 IPR013783 Immunoglobulin-like fold AFULGI_00022960 12a207bf1e243c6290fc02d28148fbeb 286 Gene3D G3DSA:1.10.287.950 2 99 2.6E-5 T 01-11-2018 AFULGI_00022960 12a207bf1e243c6290fc02d28148fbeb 286 SUPERFAMILY SSF58104 12 208 3.58E-9 T 01-11-2018 AFULGI_00003090 a5ece8991dffc8790785a1795eb988f1 143 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 5 142 10.263 T 01-11-2018 IPR022907 VapC family GO:0004540 AFULGI_00003090 a5ece8991dffc8790785a1795eb988f1 143 SMART SM00670 3 134 8.9E-29 T 01-11-2018 IPR002716 PIN domain AFULGI_00003090 a5ece8991dffc8790785a1795eb988f1 143 Pfam PF01850 PIN domain 5 138 9.7E-29 T 01-11-2018 IPR002716 PIN domain AFULGI_00003090 a5ece8991dffc8790785a1795eb988f1 143 SUPERFAMILY SSF88723 1 137 1.04E-21 T 01-11-2018 IPR029060 PIN-like domain superfamily AFULGI_00003090 a5ece8991dffc8790785a1795eb988f1 143 Gene3D G3DSA:3.40.50.1010 4 142 4.0E-15 T 01-11-2018 AFULGI_00020040 35ac8dcad50ee8128c1d23319a00f062 266 Pfam PF12146 Serine aminopeptidase, S33 20 250 3.7E-75 T 01-11-2018 IPR022742 Serine aminopeptidase, S33 AFULGI_00020040 35ac8dcad50ee8128c1d23319a00f062 266 Gene3D G3DSA:3.40.50.1820 1 265 5.1E-71 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold AFULGI_00020040 35ac8dcad50ee8128c1d23319a00f062 266 SUPERFAMILY SSF53474 4 263 3.46E-49 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold AFULGI_00020040 35ac8dcad50ee8128c1d23319a00f062 266 PRINTS PR00111 Alpha/beta hydrolase fold signature 206 220 1.3E-5 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 AFULGI_00020040 35ac8dcad50ee8128c1d23319a00f062 266 PRINTS PR00111 Alpha/beta hydrolase fold signature 94 107 1.3E-5 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 AFULGI_00020040 35ac8dcad50ee8128c1d23319a00f062 266 PRINTS PR00111 Alpha/beta hydrolase fold signature 49 64 1.3E-5 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 AFULGI_00000690 60c33674acf9090c4f787c3ff7a7d576 299 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 82 297 1.9E-76 T 01-11-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 AFULGI_00000690 60c33674acf9090c4f787c3ff7a7d576 299 Hamap MF_00978 Bifunctional ligase/repressor BirA [birA]. 8 299 30.67 T 01-11-2018 IPR030855 Bifunctional ligase/repressor BirA GO:0004077|GO:0006355 KEGG: 00780+6.3.4.15 AFULGI_00000690 60c33674acf9090c4f787c3ff7a7d576 299 TIGRFAM TIGR00122 birA_repr_reg: biotin operon repressor 8 76 1.7E-30 T 01-11-2018 IPR004409 Biotin operon repressor, helix-turn-helix domain GO:0006355 KEGG: 00780+6.3.4.15 AFULGI_00000690 60c33674acf9090c4f787c3ff7a7d576 299 Gene3D G3DSA:1.10.10.10 4 61 8.7E-13 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00000690 60c33674acf9090c4f787c3ff7a7d576 299 Pfam PF03099 Biotin/lipoate A/B protein ligase family 90 200 3.1E-14 T 01-11-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 AFULGI_00000690 60c33674acf9090c4f787c3ff7a7d576 299 Pfam PF02237 Biotin protein ligase C terminal domain 258 297 2.4E-6 T 01-11-2018 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 AFULGI_00000690 60c33674acf9090c4f787c3ff7a7d576 299 Gene3D G3DSA:3.30.930.10 70 253 6.8E-47 T 01-11-2018 AFULGI_00000690 60c33674acf9090c4f787c3ff7a7d576 299 Pfam PF08279 HTH domain 16 58 7.0E-13 T 01-11-2018 IPR013196 Helix-turn-helix, type 11 AFULGI_00000690 60c33674acf9090c4f787c3ff7a7d576 299 SUPERFAMILY SSF55681 82 253 3.11E-44 T 01-11-2018 AFULGI_00000690 60c33674acf9090c4f787c3ff7a7d576 299 SUPERFAMILY SSF46785 7 54 2.25E-9 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00000690 60c33674acf9090c4f787c3ff7a7d576 299 Gene3D G3DSA:2.30.30.100 257 299 2.8E-6 T 01-11-2018 AFULGI_00025000 8150c7ee0fc48976eb54ddebd3fb0a0c 352 Pfam PF14419 AF2226-like SPOUT RNA Methylase fused to THUMP 168 341 6.3E-79 T 01-11-2018 IPR025849 AF2226-like SPOUT RNA methylase fused to THUMP AFULGI_00025000 8150c7ee0fc48976eb54ddebd3fb0a0c 352 Gene3D G3DSA:3.30.2130.30 1 148 4.0E-22 T 01-11-2018 AFULGI_00025000 8150c7ee0fc48976eb54ddebd3fb0a0c 352 SUPERFAMILY SSF143437 9 145 4.71E-25 T 01-11-2018 AFULGI_00025000 8150c7ee0fc48976eb54ddebd3fb0a0c 352 SMART SM00981 58 147 1.6E-20 T 01-11-2018 IPR004114 THUMP domain GO:0003723 AFULGI_00025000 8150c7ee0fc48976eb54ddebd3fb0a0c 352 SUPERFAMILY SSF75217 186 335 1.92E-20 T 01-11-2018 IPR029028 Alpha/beta knot methyltransferases AFULGI_00025000 8150c7ee0fc48976eb54ddebd3fb0a0c 352 Pfam PF02926 THUMP domain 21 145 6.8E-30 T 01-11-2018 IPR004114 THUMP domain GO:0003723 AFULGI_00018110 dd0bbeaea44082cd7cf82cdfdd5a369d 1156 Gene3D G3DSA:3.40.50.300 1 224 5.8E-48 T 01-11-2018 AFULGI_00018110 dd0bbeaea44082cd7cf82cdfdd5a369d 1156 SUPERFAMILY SSF52540 1 1146 8.51E-44 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00018110 dd0bbeaea44082cd7cf82cdfdd5a369d 1156 Hamap MF_01894 Chromosome partition protein Smc [smc]. 1 1156 19.988 T 01-11-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 AFULGI_00018110 dd0bbeaea44082cd7cf82cdfdd5a369d 1156 SUPERFAMILY SSF75553 475 664 1.19E-50 T 01-11-2018 IPR036277 SMCs flexible hinge superfamily GO:0005515|GO:0005524|GO:0005694|GO:0051276 AFULGI_00018110 dd0bbeaea44082cd7cf82cdfdd5a369d 1156 SMART SM00968 515 632 1.5E-42 T 01-11-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 AFULGI_00018110 dd0bbeaea44082cd7cf82cdfdd5a369d 1156 Gene3D G3DSA:3.30.70.1620 575 658 1.1E-53 T 01-11-2018 AFULGI_00018110 dd0bbeaea44082cd7cf82cdfdd5a369d 1156 Gene3D G3DSA:1.20.5.340 669 784 1.4E-5 T 01-11-2018 AFULGI_00018110 dd0bbeaea44082cd7cf82cdfdd5a369d 1156 TIGRFAM TIGR02169 SMC_prok_A: chromosome segregation protein SMC 2 1154 0.0 T 01-11-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 AFULGI_00018110 dd0bbeaea44082cd7cf82cdfdd5a369d 1156 Gene3D G3DSA:3.40.50.300 1003 1156 5.1E-44 T 01-11-2018 AFULGI_00018110 dd0bbeaea44082cd7cf82cdfdd5a369d 1156 Gene3D G3DSA:1.20.1060.20 495 666 1.1E-53 T 01-11-2018 AFULGI_00018110 dd0bbeaea44082cd7cf82cdfdd5a369d 1156 SUPERFAMILY SSF90257 681 783 2.28E-5 T 01-11-2018 AFULGI_00018110 dd0bbeaea44082cd7cf82cdfdd5a369d 1156 PIRSF PIRSF005719 1 1156 1.6E-277 T 01-11-2018 IPR024704 Structural maintenance of chromosomes protein AFULGI_00018110 dd0bbeaea44082cd7cf82cdfdd5a369d 1156 SUPERFAMILY SSF52540 759 1144 4.51E-29 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00018110 dd0bbeaea44082cd7cf82cdfdd5a369d 1156 Pfam PF06470 SMC proteins Flexible Hinge Domain 515 631 2.0E-33 T 01-11-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 AFULGI_00018110 dd0bbeaea44082cd7cf82cdfdd5a369d 1156 TIGRFAM TIGR02168 SMC_prok_B: chromosome segregation protein SMC 3 1154 1.2E-196 T 01-11-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 AFULGI_00018110 dd0bbeaea44082cd7cf82cdfdd5a369d 1156 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 1147 2.4E-61 T 01-11-2018 IPR003395 RecF/RecN/SMC, N-terminal AFULGI_00023950 69c4e699f5a8ceb7f6c4b634baab861f 340 Pfam PF01925 Sulfite exporter TauE/SafE 22 327 8.0E-29 T 01-11-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 AFULGI_00004600 a18eb72a6f73251a273418580fdfb797 305 Pfam PF00989 PAS fold 4 94 4.3E-5 T 01-11-2018 IPR013767 PAS fold GO:0006355 AFULGI_00004600 a18eb72a6f73251a273418580fdfb797 305 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 6 84 1.6E-6 T 01-11-2018 IPR000014 PAS domain AFULGI_00004600 a18eb72a6f73251a273418580fdfb797 305 SUPERFAMILY SSF55785 3 104 4.57E-7 T 01-11-2018 IPR035965 PAS domain superfamily AFULGI_00004600 a18eb72a6f73251a273418580fdfb797 305 Gene3D G3DSA:3.30.450.20 2 119 1.7E-9 T 01-11-2018 AFULGI_00019300 011030056615ebc5292c88ef7c1f472c 169 ProDom PD111187 AF1681 5 169 1.0E-88 T 01-11-2018 IPR035235 Protein of unknown function DUF5343 AFULGI_00019300 011030056615ebc5292c88ef7c1f472c 169 Pfam PF17278 Family of unknown function (DUF5343) 5 82 7.7E-27 T 01-11-2018 IPR035235 Protein of unknown function DUF5343 AFULGI_00006640 32bbd4020a5cb4d3a610cf73a31f67c9 284 Hamap MF_00583_A Putative ribose-phosphate pyrophosphokinase [prs]. 2 281 34.316 T 01-11-2018 IPR037514 Ribose-phosphate pyrophosphokinase, archaea GO:0004749 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 AFULGI_00006640 32bbd4020a5cb4d3a610cf73a31f67c9 284 SMART SM01400 1 116 1.4E-25 T 01-11-2018 AFULGI_00006640 32bbd4020a5cb4d3a610cf73a31f67c9 284 Gene3D G3DSA:3.40.50.2020 141 273 2.9E-71 T 01-11-2018 AFULGI_00006640 32bbd4020a5cb4d3a610cf73a31f67c9 284 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 1 283 2.1E-90 T 01-11-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 AFULGI_00006640 32bbd4020a5cb4d3a610cf73a31f67c9 284 SUPERFAMILY SSF53271 105 276 1.31E-27 T 01-11-2018 IPR029057 Phosphoribosyltransferase-like AFULGI_00006640 32bbd4020a5cb4d3a610cf73a31f67c9 284 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 1 116 1.8E-22 T 01-11-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 AFULGI_00006640 32bbd4020a5cb4d3a610cf73a31f67c9 284 Gene3D G3DSA:3.40.50.2020 6 280 2.9E-71 T 01-11-2018 AFULGI_00006640 32bbd4020a5cb4d3a610cf73a31f67c9 284 SUPERFAMILY SSF53271 1 152 9.49E-28 T 01-11-2018 IPR029057 Phosphoribosyltransferase-like AFULGI_00006640 32bbd4020a5cb4d3a610cf73a31f67c9 284 Pfam PF00156 Phosphoribosyl transferase domain 143 242 6.9E-10 T 01-11-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 AFULGI_00024670 a9afc388ad597e8fbb6c2c7581396607 301 Pfam PF01916 Deoxyhypusine synthase 16 293 6.2E-97 T 01-11-2018 IPR002773 Deoxyhypusine synthase GO:0008612 Reactome: R-HSA-204626 AFULGI_00024670 a9afc388ad597e8fbb6c2c7581396607 301 Hamap MF_00153 Probable deoxyhypusine synthase [dys]. 14 295 42.788 T 01-11-2018 IPR022899 Deoxyhypusine synthase, putative, archaeal GO:0034038 AFULGI_00024670 a9afc388ad597e8fbb6c2c7581396607 301 SUPERFAMILY SSF52467 3 298 9.81E-101 T 01-11-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily AFULGI_00024670 a9afc388ad597e8fbb6c2c7581396607 301 TIGRFAM TIGR00321 dhys: deoxyhypusine synthase 2 296 2.4E-132 T 01-11-2018 IPR002773 Deoxyhypusine synthase GO:0008612 Reactome: R-HSA-204626 AFULGI_00024670 a9afc388ad597e8fbb6c2c7581396607 301 Gene3D G3DSA:3.40.910.10 1 301 8.2E-97 T 01-11-2018 IPR036982 Deoxyhypusine synthase superfamily GO:0008612 Reactome: R-HSA-204626 AFULGI_00022690 92438adfca5a2c3e71a3ad20895499a4 200 Pfam PF12804 MobA-like NTP transferase domain 4 153 5.2E-24 T 01-11-2018 IPR025877 MobA-like NTP transferase AFULGI_00022690 92438adfca5a2c3e71a3ad20895499a4 200 Gene3D G3DSA:3.90.550.10 1 200 5.7E-57 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFULGI_00022690 92438adfca5a2c3e71a3ad20895499a4 200 SUPERFAMILY SSF53448 2 185 5.63E-21 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFULGI_00006740 4535dfe1082ef1b769f303390daf5e42 250 Gene3D G3DSA:3.90.550.10 40 189 2.0E-9 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFULGI_00006740 4535dfe1082ef1b769f303390daf5e42 250 SUPERFAMILY SSF53448 48 248 1.26E-18 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFULGI_00006740 4535dfe1082ef1b769f303390daf5e42 250 Pfam PF00535 Glycosyl transferase family 2 87 133 1.1E-5 T 01-11-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 AFULGI_00013170 fa03d9b62d4aa5f20c25db81f579db23 97 Pfam PF10826 Protein of unknown function (DUF2551) 9 89 7.2E-31 T 01-11-2018 IPR020501 Uncharacterised protein family AF1218 AFULGI_00013170 fa03d9b62d4aa5f20c25db81f579db23 97 ProDom PD066267 AF1218 MA3722 MA2389 11 96 3.0E-35 T 01-11-2018 IPR020501 Uncharacterised protein family AF1218 AFULGI_00007440 f1f64616de5e0ffedeeb32ab8c5cd932 402 Pfam PF01629 Domain of unknown function DUF22 4 111 5.5E-32 T 01-11-2018 IPR002572 Domain of unknown function DUF22 AFULGI_00007440 f1f64616de5e0ffedeeb32ab8c5cd932 402 Pfam PF01629 Domain of unknown function DUF22 149 252 5.4E-25 T 01-11-2018 IPR002572 Domain of unknown function DUF22 AFULGI_00007440 f1f64616de5e0ffedeeb32ab8c5cd932 402 Pfam PF01629 Domain of unknown function DUF22 289 381 9.4E-18 T 01-11-2018 IPR002572 Domain of unknown function DUF22 AFULGI_00023420 f73886a58263dff0b7bff57e3812d533 301 PIRSF PIRSF006414 2 298 8.3E-140 T 01-11-2018 IPR014053 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr GO:0006730|GO:0030270 AFULGI_00023420 f73886a58263dff0b7bff57e3812d533 301 Gene3D G3DSA:3.30.70.520 4 296 3.4E-114 T 01-11-2018 IPR023447 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr, ferredoxin-like superfamily AFULGI_00023420 f73886a58263dff0b7bff57e3812d533 301 Gene3D G3DSA:3.30.70.520 18 165 3.4E-114 T 01-11-2018 IPR023447 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr, ferredoxin-like superfamily AFULGI_00023420 f73886a58263dff0b7bff57e3812d533 301 SUPERFAMILY SSF55112 150 297 3.66E-52 T 01-11-2018 IPR023447 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr, ferredoxin-like superfamily AFULGI_00023420 f73886a58263dff0b7bff57e3812d533 301 SUPERFAMILY SSF55112 2 148 6.8E-45 T 01-11-2018 IPR023447 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr, ferredoxin-like superfamily AFULGI_00023420 f73886a58263dff0b7bff57e3812d533 301 Pfam PF02741 FTR, proximal lobe 150 296 9.7E-58 T 01-11-2018 IPR002770 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr, C-terminal GO:0006730|GO:0016740 AFULGI_00023420 f73886a58263dff0b7bff57e3812d533 301 Pfam PF01913 Formylmethanofuran-tetrahydromethanopterin formyltransferase 2 147 2.2E-47 T 01-11-2018 IPR022667 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr, N-terminal GO:0006730|GO:0016740 AFULGI_00003130 7486f9397932cbda689613c976b72435 151 SMART SM00670 3 142 1.2E-25 T 01-11-2018 IPR002716 PIN domain AFULGI_00003130 7486f9397932cbda689613c976b72435 151 SUPERFAMILY SSF88723 1 145 1.12E-16 T 01-11-2018 IPR029060 PIN-like domain superfamily AFULGI_00003130 7486f9397932cbda689613c976b72435 151 Pfam PF01850 PIN domain 5 146 2.9E-29 T 01-11-2018 IPR002716 PIN domain AFULGI_00003130 7486f9397932cbda689613c976b72435 151 Gene3D G3DSA:3.40.50.1010 3 150 1.3E-9 T 01-11-2018 AFULGI_00009300 2afee1241008ce208dbeeb8b800246fe 494 TIGRFAM TIGR00831 a_cpa1: Na+/H+ antiporter 7 494 1.9E-212 T 01-11-2018 IPR004705 Cation/H+ exchanger, CPA1 family, bacteria GO:0006812|GO:0015299|GO:0016021 AFULGI_00009300 2afee1241008ce208dbeeb8b800246fe 494 Gene3D G3DSA:1.20.1530.20 2 386 4.4E-15 T 01-11-2018 IPR038770 Sodium/solute symporter superfamily AFULGI_00009300 2afee1241008ce208dbeeb8b800246fe 494 Pfam PF00999 Sodium/hydrogen exchanger family 13 376 1.3E-75 T 01-11-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 AFULGI_00009300 2afee1241008ce208dbeeb8b800246fe 494 PRINTS PR01084 Na+/H+ exchanger signature 119 129 9.6E-6 T 01-11-2018 IPR004709 Na+/H+ exchanger GO:0006814|GO:0006885|GO:0015385|GO:0016021|GO:0055085 Reactome: R-HSA-425986 AFULGI_00009300 2afee1241008ce208dbeeb8b800246fe 494 PRINTS PR01084 Na+/H+ exchanger signature 85 93 9.6E-6 T 01-11-2018 IPR004709 Na+/H+ exchanger GO:0006814|GO:0006885|GO:0015385|GO:0016021|GO:0055085 Reactome: R-HSA-425986 AFULGI_00009300 2afee1241008ce208dbeeb8b800246fe 494 PRINTS PR01084 Na+/H+ exchanger signature 56 67 9.6E-6 T 01-11-2018 IPR004709 Na+/H+ exchanger GO:0006814|GO:0006885|GO:0015385|GO:0016021|GO:0055085 Reactome: R-HSA-425986 AFULGI_00019160 ff2ceb66388541e1d941b6056acd8c38 456 Hamap MF_00066 Sulfate adenylyltransferase [sat]. 38 426 43.53 T 01-11-2018 IPR020792 Sulphate adenylyltransferase, prokaryotic-type GO:0000103|GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 AFULGI_00019160 ff2ceb66388541e1d941b6056acd8c38 456 TIGRFAM TIGR00339 sopT: sulfate adenylyltransferase 9 422 4.6E-156 T 01-11-2018 IPR002650 Sulphate adenylyltransferase GO:0000103|GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 AFULGI_00019160 ff2ceb66388541e1d941b6056acd8c38 456 SUPERFAMILY SSF52374 192 423 1.43E-60 T 01-11-2018 AFULGI_00019160 ff2ceb66388541e1d941b6056acd8c38 456 Gene3D G3DSA:3.10.400.10 7 183 1.2E-26 T 01-11-2018 AFULGI_00019160 ff2ceb66388541e1d941b6056acd8c38 456 Pfam PF14306 PUA-like domain 8 184 2.1E-31 T 01-11-2018 IPR025980 ATP-sulfurylase PUA-like domain KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 AFULGI_00019160 ff2ceb66388541e1d941b6056acd8c38 456 Pfam PF01747 ATP-sulfurylase 194 423 1.9E-69 T 01-11-2018 IPR024951 Sulphate adenylyltransferase catalytic domain GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 AFULGI_00019160 ff2ceb66388541e1d941b6056acd8c38 456 Gene3D G3DSA:3.40.50.620 196 422 6.0E-67 T 01-11-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFULGI_00019160 ff2ceb66388541e1d941b6056acd8c38 456 SUPERFAMILY SSF88697 8 189 4.97E-32 T 01-11-2018 IPR015947 PUA-like superfamily AFULGI_00002530 dae47e7e7ed24d42f4c75688a89c2677 551 SUPERFAMILY SSF56801 7 548 1.57E-132 T 01-11-2018 AFULGI_00002530 dae47e7e7ed24d42f4c75688a89c2677 551 Gene3D G3DSA:3.30.300.310 445 551 1.8E-35 T 01-11-2018 AFULGI_00002530 dae47e7e7ed24d42f4c75688a89c2677 551 Pfam PF00501 AMP-binding enzyme 24 449 2.1E-89 T 01-11-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFULGI_00002530 dae47e7e7ed24d42f4c75688a89c2677 551 Pfam PF13193 AMP-binding enzyme C-terminal domain 459 535 4.8E-20 T 01-11-2018 IPR025110 AMP-binding enzyme, C-terminal domain AFULGI_00002530 dae47e7e7ed24d42f4c75688a89c2677 551 Gene3D G3DSA:3.40.50.12780 3 444 5.6E-113 T 01-11-2018 AFULGI_00022360 04d47899da85b387418b42ade690b54c 398 Hamap MF_00553 Proteasome-activating nucleotidase [pan]. 1 397 49.929 T 01-11-2018 IPR023501 Proteasome-activating nucleotidase PAN AFULGI_00022360 04d47899da85b387418b42ade690b54c 398 SMART SM00382 174 313 1.0E-24 T 01-11-2018 IPR003593 AAA+ ATPase domain AFULGI_00022360 04d47899da85b387418b42ade690b54c 398 ProSitePatterns PS00674 AAA-protein family signature. 281 299 - T 01-11-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 AFULGI_00022360 04d47899da85b387418b42ade690b54c 398 Gene3D G3DSA:1.10.8.60 312 383 4.9E-29 T 01-11-2018 AFULGI_00022360 04d47899da85b387418b42ade690b54c 398 TIGRFAM TIGR01242 26Sp45: 26S proteasome subunit P45 family 21 383 1.6E-210 T 01-11-2018 IPR005937 26S proteasome regulatory subunit P45-like GO:0005737|GO:0016787|GO:0030163 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 AFULGI_00022360 04d47899da85b387418b42ade690b54c 398 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 178 311 2.4E-45 T 01-11-2018 IPR003959 ATPase, AAA-type, core GO:0005524 AFULGI_00022360 04d47899da85b387418b42ade690b54c 398 SUPERFAMILY SSF52540 136 385 2.52E-72 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00022360 04d47899da85b387418b42ade690b54c 398 Gene3D G3DSA:3.40.50.300 131 311 2.0E-70 T 01-11-2018 AFULGI_00022360 04d47899da85b387418b42ade690b54c 398 Gene3D G3DSA:2.40.50.140 26 130 2.0E-32 T 01-11-2018 AFULGI_00000200 3c9dde873960ac9bef9f509ffeac26d9 91 Gene3D G3DSA:3.10.20.30 1 91 3.2E-12 T 01-11-2018 IPR012675 Beta-grasp domain superfamily AFULGI_00000200 3c9dde873960ac9bef9f509ffeac26d9 91 Pfam PF02597 ThiS family 17 91 6.2E-14 T 01-11-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 AFULGI_00000200 3c9dde873960ac9bef9f509ffeac26d9 91 SUPERFAMILY SSF54285 1 91 2.76E-12 T 01-11-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp AFULGI_00001650 00501183e82d85d248c2898214d9be1f 60 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 10 21 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFULGI_00001650 00501183e82d85d248c2898214d9be1f 60 Gene3D G3DSA:3.30.70.20 1 60 3.8E-21 T 01-11-2018 AFULGI_00001650 00501183e82d85d248c2898214d9be1f 60 SUPERFAMILY SSF54862 1 59 6.02E-14 T 01-11-2018 AFULGI_00001650 00501183e82d85d248c2898214d9be1f 60 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 5 57 1.2E-14 T 01-11-2018 AFULGI_00001650 00501183e82d85d248c2898214d9be1f 60 PRINTS PR00352 3Fe-4S ferredoxin signature 44 56 5.6E-10 T 01-11-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 AFULGI_00001650 00501183e82d85d248c2898214d9be1f 60 PRINTS PR00352 3Fe-4S ferredoxin signature 16 26 5.6E-10 T 01-11-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 AFULGI_00001650 00501183e82d85d248c2898214d9be1f 60 PRINTS PR00352 3Fe-4S ferredoxin signature 5 16 5.6E-10 T 01-11-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 AFULGI_00007690 7fe2940f6b3b2db30ffe7bfeb8e59f3d 368 Pfam PF14697 4Fe-4S dicluster domain 282 336 9.4E-10 T 01-11-2018 AFULGI_00007690 7fe2940f6b3b2db30ffe7bfeb8e59f3d 368 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 320 331 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFULGI_00007690 7fe2940f6b3b2db30ffe7bfeb8e59f3d 368 SUPERFAMILY SSF54862 282 342 1.04E-18 T 01-11-2018 AFULGI_00007690 7fe2940f6b3b2db30ffe7bfeb8e59f3d 368 Gene3D G3DSA:3.30.70.20 309 343 4.7E-7 T 01-11-2018 AFULGI_00007690 7fe2940f6b3b2db30ffe7bfeb8e59f3d 368 Gene3D G3DSA:3.30.70.20 254 308 4.2E-5 T 01-11-2018 AFULGI_00012620 0e16d65f54f8847e90ffe5dc9858413d 188 Pfam PF01991 ATP synthase (E/31 kDa) subunit 9 187 4.9E-46 T 01-11-2018 IPR002842 V-type ATPase subunit E GO:0015991|GO:0033178|GO:0046961 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 AFULGI_00012620 0e16d65f54f8847e90ffe5dc9858413d 188 Hamap MF_00311 V-type proton ATPase subunit E [atpE]. 1 188 14.168 T 01-11-2018 IPR002842 V-type ATPase subunit E GO:0015991|GO:0033178|GO:0046961 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 AFULGI_00012620 0e16d65f54f8847e90ffe5dc9858413d 188 SUPERFAMILY SSF160527 80 187 2.22E-23 T 01-11-2018 AFULGI_00012620 0e16d65f54f8847e90ffe5dc9858413d 188 Gene3D G3DSA:3.30.2320.30 80 187 1.2E-19 T 01-11-2018 IPR038495 V-type ATPase subunit E, C-terminal domain superfamily Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 AFULGI_00007770 0ecd1e838793981a0515efefa2b05010 361 SUPERFAMILY SSF46785 276 354 8.5E-11 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00007770 0ecd1e838793981a0515efefa2b05010 361 Gene3D G3DSA:3.40.50.300 24 193 6.1E-63 T 01-11-2018 AFULGI_00007770 0ecd1e838793981a0515efefa2b05010 361 TIGRFAM TIGR02928 TIGR02928: orc1/cdc6 family replication initiation protein 8 344 1.4E-61 T 01-11-2018 IPR014277 Orc1/Cdc6-type DNA replication protein, archaea AFULGI_00007770 0ecd1e838793981a0515efefa2b05010 361 Gene3D G3DSA:1.10.10.10 273 361 2.0E-5 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00007770 0ecd1e838793981a0515efefa2b05010 361 SMART SM01074 287 358 5.7E-15 T 01-11-2018 IPR015163 Cdc6, C-terminal Reactome: R-HSA-176187|Reactome: R-HSA-539107|Reactome: R-HSA-68689|Reactome: R-HSA-68827|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962 AFULGI_00007770 0ecd1e838793981a0515efefa2b05010 361 SUPERFAMILY SSF52540 8 265 1.98E-32 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00007770 0ecd1e838793981a0515efefa2b05010 361 Hamap MF_01407 ORC1-type DNA replication protein. 1 358 23.359 T 01-11-2018 IPR014277 Orc1/Cdc6-type DNA replication protein, archaea AFULGI_00007770 0ecd1e838793981a0515efefa2b05010 361 Gene3D G3DSA:1.10.8.60 8 265 6.1E-63 T 01-11-2018 AFULGI_00008010 53fcc51c686849bff76b7976dfa0eb44 132 SUPERFAMILY SSF53800 2 122 3.92E-24 T 01-11-2018 AFULGI_00008010 53fcc51c686849bff76b7976dfa0eb44 132 Pfam PF01903 CbiX 10 117 3.9E-18 T 01-11-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 AFULGI_00008010 53fcc51c686849bff76b7976dfa0eb44 132 Hamap MF_00785 Sirohydrochlorin cobaltochelatase [cbiX]. 2 124 24.916 T 01-11-2018 IPR023652 Sirohydrochlorin cobaltochelatase GO:0016852|GO:0050897 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 AFULGI_00008010 53fcc51c686849bff76b7976dfa0eb44 132 Gene3D G3DSA:3.40.50.1400 1 132 1.1E-29 T 01-11-2018 AFULGI_00004270 58b7541d89e4faeb6ea3618fbc45e259 418 SUPERFAMILY SSF55124 3 167 1.94E-73 T 01-11-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AFULGI_00004270 58b7541d89e4faeb6ea3618fbc45e259 418 SUPERFAMILY SSF54862 229 303 1.26E-19 T 01-11-2018 AFULGI_00004270 58b7541d89e4faeb6ea3618fbc45e259 418 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 91 155 1.4E-7 T 01-11-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AFULGI_00004270 58b7541d89e4faeb6ea3618fbc45e259 418 SUPERFAMILY SSF56014 167 403 3.6E-60 T 01-11-2018 AFULGI_00004270 58b7541d89e4faeb6ea3618fbc45e259 418 Gene3D G3DSA:3.30.70.2500 63 164 1.3E-51 T 01-11-2018 AFULGI_00004270 58b7541d89e4faeb6ea3618fbc45e259 418 Gene3D G3DSA:3.30.413.10 165 398 3.1E-115 T 01-11-2018 AFULGI_00004270 58b7541d89e4faeb6ea3618fbc45e259 418 TIGRFAM TIGR02064 dsrA: sulfite reductase, dissimilatory-type alpha subunit 7 408 2.0E-212 T 01-11-2018 IPR011806 Sulphite reductase, dissimilatory-type alpha subunit GO:0018551|GO:0020037|GO:0051539|GO:0055114 AFULGI_00004270 58b7541d89e4faeb6ea3618fbc45e259 418 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 166 381 3.1E-45 T 01-11-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AFULGI_00004270 58b7541d89e4faeb6ea3618fbc45e259 418 Gene3D G3DSA:3.30.70.20 239 306 3.1E-115 T 01-11-2018 AFULGI_00020210 5fc86d8f1e1ee07971006a31ccf98cac 313 Pfam PF00005 ABC transporter 23 179 2.1E-31 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFULGI_00020210 5fc86d8f1e1ee07971006a31ccf98cac 313 SUPERFAMILY SSF52540 3 249 6.41E-71 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00020210 5fc86d8f1e1ee07971006a31ccf98cac 313 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 230 293 2.1E-18 T 01-11-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 AFULGI_00020210 5fc86d8f1e1ee07971006a31ccf98cac 313 SMART SM00382 32 228 2.5E-17 T 01-11-2018 IPR003593 AAA+ ATPase domain AFULGI_00020210 5fc86d8f1e1ee07971006a31ccf98cac 313 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFULGI_00020210 5fc86d8f1e1ee07971006a31ccf98cac 313 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 229 311 6.8E-24 T 01-11-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 AFULGI_00020210 5fc86d8f1e1ee07971006a31ccf98cac 313 Gene3D G3DSA:3.40.50.300 1 313 3.8E-98 T 01-11-2018 AFULGI_00013950 9c9b76a545bd91727c1d1779ecaab0eb 273 Gene3D G3DSA:3.40.800.20 22 273 5.7E-48 T 01-11-2018 IPR037138 Histone deacetylase domain superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 AFULGI_00013950 9c9b76a545bd91727c1d1779ecaab0eb 273 Pfam PF00850 Histone deacetylase domain 70 153 4.4E-23 T 01-11-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 AFULGI_00013950 9c9b76a545bd91727c1d1779ecaab0eb 273 SUPERFAMILY SSF52768 3 272 1.29E-49 T 01-11-2018 IPR023696 Ureohydrolase domain superfamily AFULGI_00013950 9c9b76a545bd91727c1d1779ecaab0eb 273 PRINTS PR01270 Histone deacetylase superfamily signature 202 212 9.2E-13 T 01-11-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 AFULGI_00013950 9c9b76a545bd91727c1d1779ecaab0eb 273 PRINTS PR01270 Histone deacetylase superfamily signature 134 149 9.2E-13 T 01-11-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 AFULGI_00013950 9c9b76a545bd91727c1d1779ecaab0eb 273 PRINTS PR01270 Histone deacetylase superfamily signature 100 123 9.2E-13 T 01-11-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 AFULGI_00013950 9c9b76a545bd91727c1d1779ecaab0eb 273 Pfam PF00850 Histone deacetylase domain 184 268 8.8E-8 T 01-11-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 AFULGI_00008630 257e6c1c227a3b737661be99afdb7ac1 193 Gene3D G3DSA:2.20.25.420 2 43 5.2E-6 T 01-11-2018 AFULGI_00008630 257e6c1c227a3b737661be99afdb7ac1 193 Pfam PF03367 ZPR1 zinc-finger domain 3 154 7.8E-34 T 01-11-2018 IPR004457 Zinc finger, ZPR1-type GO:0008270 AFULGI_00008630 257e6c1c227a3b737661be99afdb7ac1 193 Gene3D G3DSA:2.60.120.1040 47 176 8.4E-18 T 01-11-2018 AFULGI_00008630 257e6c1c227a3b737661be99afdb7ac1 193 TIGRFAM TIGR00310 ZPR1_znf: ZPR1 zinc finger domain 2 190 2.3E-90 T 01-11-2018 IPR004457 Zinc finger, ZPR1-type GO:0008270 AFULGI_00008630 257e6c1c227a3b737661be99afdb7ac1 193 TIGRFAM TIGR00340 zpr1_rel: zinc finger protein ZPR1 homolog 4 164 2.8E-71 T 01-11-2018 IPR004470 Zinc finger, ZPR1-type, subgroup GO:0008270 AFULGI_00008630 257e6c1c227a3b737661be99afdb7ac1 193 SMART SM00709 2 156 6.5E-74 T 01-11-2018 IPR004457 Zinc finger, ZPR1-type GO:0008270 AFULGI_00022650 1772dcfbcd1d3df6c02da34c9bb463cb 178 SUPERFAMILY SSF52540 1 148 4.35E-18 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00022650 1772dcfbcd1d3df6c02da34c9bb463cb 178 Gene3D G3DSA:3.40.50.300 1 178 1.5E-40 T 01-11-2018 AFULGI_00022650 1772dcfbcd1d3df6c02da34c9bb463cb 178 Hamap MF_00039 Putative adenylate kinase. 1 155 25.892 T 01-11-2018 IPR020618 Adenylate kinase isoenzyme 6 GO:0004017|GO:0005524 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 AFULGI_00022650 1772dcfbcd1d3df6c02da34c9bb463cb 178 Pfam PF13238 AAA domain 3 112 7.8E-19 T 01-11-2018 AFULGI_00008270 3aedbe9fda62e0fca0ca41eb88f6cae1 249 TIGRFAM TIGR00736 nifR3_rel_arch: putative TIM-barrel protein 12 229 1.4E-102 T 01-11-2018 IPR005270 tRNA-dihydrouridine synthase, TIM-barrel, NifR3-related AFULGI_00008270 3aedbe9fda62e0fca0ca41eb88f6cae1 249 SUPERFAMILY SSF51395 5 232 2.04E-21 T 01-11-2018 AFULGI_00008270 3aedbe9fda62e0fca0ca41eb88f6cae1 249 Gene3D G3DSA:3.20.20.70 3 233 7.1E-15 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFULGI_00024480 4666ff721562b7e81019db17537eb79e 862 SMART SM00490 296 380 6.4E-20 T 01-11-2018 IPR001650 Helicase, C-terminal AFULGI_00024480 4666ff721562b7e81019db17537eb79e 862 SMART SM00487 28 251 1.7E-31 T 01-11-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFULGI_00024480 4666ff721562b7e81019db17537eb79e 862 Gene3D G3DSA:3.40.50.300 258 413 1.2E-26 T 01-11-2018 AFULGI_00024480 4666ff721562b7e81019db17537eb79e 862 Pfam PF00270 DEAD/DEAH box helicase 33 217 1.3E-28 T 01-11-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 AFULGI_00024480 4666ff721562b7e81019db17537eb79e 862 Gene3D G3DSA:3.40.50.300 10 234 1.0E-55 T 01-11-2018 AFULGI_00024480 4666ff721562b7e81019db17537eb79e 862 SUPERFAMILY SSF52540 44 381 4.94E-48 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00024480 4666ff721562b7e81019db17537eb79e 862 Pfam PF08494 DEAD/H associated 639 825 6.0E-53 T 01-11-2018 IPR013701 DEAD/H associated GO:0005524|GO:0016818 AFULGI_00024480 4666ff721562b7e81019db17537eb79e 862 Pfam PF00271 Helicase conserved C-terminal domain 269 376 1.1E-17 T 01-11-2018 IPR001650 Helicase, C-terminal AFULGI_00024480 4666ff721562b7e81019db17537eb79e 862 PIRSF PIRSF037307 4 860 8.9E-275 T 01-11-2018 IPR017170 Lhr-like ATP-dependent RNA helicase, predicted GO:0005524|GO:0016818 AFULGI_00003380 02270b7b19d1878eb8597f0960c8897a 380 SUPERFAMILY SSF56796 2 376 9.68E-100 T 01-11-2018 AFULGI_00003380 02270b7b19d1878eb8597f0960c8897a 380 Gene3D G3DSA:3.40.50.1970 1 179 9.6E-44 T 01-11-2018 AFULGI_00003380 02270b7b19d1878eb8597f0960c8897a 380 Gene3D G3DSA:1.20.1090.10 180 378 6.2E-54 T 01-11-2018 AFULGI_00003380 02270b7b19d1878eb8597f0960c8897a 380 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 168 196 - T 01-11-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 AFULGI_00003380 02270b7b19d1878eb8597f0960c8897a 380 Pfam PF00465 Iron-containing alcohol dehydrogenase 8 363 8.3E-97 T 01-11-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 AFULGI_00025540 158462f9f7a2b54efd7d352975f1e018 420 Hamap MF_01892 tRNA(Ile2) 2-agmatinylcytidine synthetase TiaS [tiaS]. 3 419 37.799 T 01-11-2018 IPR024913 tRNA(Ile2) 2-agmatinylcytidine synthetase TiaS GO:0002101|GO:0016879 AFULGI_00025540 158462f9f7a2b54efd7d352975f1e018 420 Gene3D G3DSA:2.40.50.1010 250 398 3.2E-61 T 01-11-2018 AFULGI_00025540 158462f9f7a2b54efd7d352975f1e018 420 Gene3D G3DSA:3.30.70.2200 2 154 1.0E-47 T 01-11-2018 AFULGI_00025540 158462f9f7a2b54efd7d352975f1e018 420 Pfam PF08489 Domain of unknown function (DUF1743) 139 251 4.3E-41 T 01-11-2018 IPR013696 Domain of unknown function DUF1743 AFULGI_00025540 158462f9f7a2b54efd7d352975f1e018 420 Pfam PF01336 OB-fold nucleic acid binding domain 268 329 1.5E-6 T 01-11-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 AFULGI_00025540 158462f9f7a2b54efd7d352975f1e018 420 Gene3D G3DSA:3.90.600.20 155 249 4.0E-32 T 01-11-2018 AFULGI_00000900 60a4a65b74c7ee27d5b8585bfa7969f6 240 Pfam PF00005 ABC transporter 17 154 2.9E-32 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFULGI_00000900 60a4a65b74c7ee27d5b8585bfa7969f6 240 Gene3D G3DSA:3.40.50.300 1 240 3.4E-76 T 01-11-2018 AFULGI_00000900 60a4a65b74c7ee27d5b8585bfa7969f6 240 SMART SM00382 23 204 1.1E-11 T 01-11-2018 IPR003593 AAA+ ATPase domain AFULGI_00000900 60a4a65b74c7ee27d5b8585bfa7969f6 240 ProSitePatterns PS00211 ABC transporters family signature. 127 141 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFULGI_00000900 60a4a65b74c7ee27d5b8585bfa7969f6 240 SUPERFAMILY SSF52540 8 230 1.77E-73 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00002460 1aa7b25be1a25bc46073d18f3f0f21f4 369 SUPERFAMILY SSF54001 174 236 3.08E-5 T 01-11-2018 IPR038765 Papain-like cysteine peptidase superfamily AFULGI_00022750 0cadcf3c915fbacbde64cbf0d4ca3d2a 86 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 4 45 1.8E-19 T 01-11-2018 IPR007159 SpoVT-AbrB domain GO:0003677 AFULGI_00022750 0cadcf3c915fbacbde64cbf0d4ca3d2a 86 SUPERFAMILY SSF89447 2 62 7.85E-15 T 01-11-2018 IPR037914 SpoVT-AbrB domain superfamily AFULGI_00022750 0cadcf3c915fbacbde64cbf0d4ca3d2a 86 Gene3D G3DSA:2.10.260.10 3 43 2.1E-15 T 01-11-2018 AFULGI_00022750 0cadcf3c915fbacbde64cbf0d4ca3d2a 86 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 5 49 7.8E-15 T 01-11-2018 IPR007159 SpoVT-AbrB domain GO:0003677 AFULGI_00022750 0cadcf3c915fbacbde64cbf0d4ca3d2a 86 SMART SM00966 5 50 5.2E-17 T 01-11-2018 IPR007159 SpoVT-AbrB domain GO:0003677 AFULGI_00015950 c13d512a6418396005c651167a0abe4d 466 PRINTS PR01874 DNA repair protein radA signature 416 442 2.0E-10 T 01-11-2018 AFULGI_00015950 c13d512a6418396005c651167a0abe4d 466 PRINTS PR01874 DNA repair protein radA signature 245 273 2.0E-10 T 01-11-2018 AFULGI_00015950 c13d512a6418396005c651167a0abe4d 466 Gene3D G3DSA:3.40.50.300 225 466 2.5E-35 T 01-11-2018 AFULGI_00015950 c13d512a6418396005c651167a0abe4d 466 SUPERFAMILY SSF52540 2 221 8.45E-34 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00015950 c13d512a6418396005c651167a0abe4d 466 Pfam PF06745 KaiC 3 221 7.4E-44 T 01-11-2018 IPR014774 KaiC-like domain AFULGI_00015950 c13d512a6418396005c651167a0abe4d 466 Pfam PF06745 KaiC 236 308 1.3E-9 T 01-11-2018 IPR014774 KaiC-like domain AFULGI_00015950 c13d512a6418396005c651167a0abe4d 466 Pfam PF06745 KaiC 329 450 9.0E-8 T 01-11-2018 IPR014774 KaiC-like domain AFULGI_00015950 c13d512a6418396005c651167a0abe4d 466 Gene3D G3DSA:3.40.50.300 1 223 2.2E-46 T 01-11-2018 AFULGI_00015950 c13d512a6418396005c651167a0abe4d 466 SUPERFAMILY SSF52540 232 452 2.88E-30 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00001330 6add98cdfff7abc141da98f07df03f79 185 ProDom PD695862 AF1173 AF0136 AF2020 1 182 1.0E-94 T 01-11-2018 AFULGI_00024900 af4345fa301f59a9fd86a57af616389e 548 SUPERFAMILY SSF51703 3 542 2.35E-232 T 01-11-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 AFULGI_00024900 af4345fa301f59a9fd86a57af616389e 548 Gene3D G3DSA:3.20.20.240 1 548 7.6E-274 T 01-11-2018 AFULGI_00024900 af4345fa301f59a9fd86a57af616389e 548 Pfam PF01642 Methylmalonyl-CoA mutase 26 540 8.7E-245 T 01-11-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 AFULGI_00024900 af4345fa301f59a9fd86a57af616389e 548 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 25 547 1.6E-290 T 01-11-2018 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 AFULGI_00021760 c21e4035aadff16ded758372a6fd220c 102 SUPERFAMILY SSF101744 9 94 1.26E-26 T 01-11-2018 IPR023534 Rof/RNase P-like Reactome: R-HSA-6784531 AFULGI_00021760 c21e4035aadff16ded758372a6fd220c 102 Gene3D G3DSA:2.30.30.210 1 102 1.5E-40 T 01-11-2018 IPR036980 Ribonuclease P/MRP, subunit p29 superfamily GO:0003723|GO:0004540|GO:0008033|GO:0030677 Reactome: R-HSA-6784531 AFULGI_00021760 c21e4035aadff16ded758372a6fd220c 102 Hamap MF_00754 Ribonuclease P protein component 1 [rnp1]. 12 88 17.647 T 01-11-2018 IPR023538 Ribonuclease P protein component 1 GO:0001682|GO:0004526 AFULGI_00021760 c21e4035aadff16ded758372a6fd220c 102 SMART SM00538 4 94 1.6E-42 T 01-11-2018 IPR002730 Ribonuclease P/MRP, subunit p29 GO:0003723|GO:0004540|GO:0006396|GO:0030677 Reactome: R-HSA-6784531 AFULGI_00021760 c21e4035aadff16ded758372a6fd220c 102 Pfam PF01868 Domain of unknown function UPF0086 9 89 6.0E-23 T 01-11-2018 IPR002730 Ribonuclease P/MRP, subunit p29 GO:0003723|GO:0004540|GO:0006396|GO:0030677 Reactome: R-HSA-6784531 AFULGI_00022820 9beef18888372ee9b576a8023bbac764 281 Gene3D G3DSA:3.40.50.720 1 162 4.2E-65 T 01-11-2018 AFULGI_00022820 9beef18888372ee9b576a8023bbac764 281 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 164 259 4.9E-21 T 01-11-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 AFULGI_00022820 9beef18888372ee9b576a8023bbac764 281 Gene3D G3DSA:1.10.1040.10 163 279 2.8E-27 T 01-11-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AFULGI_00022820 9beef18888372ee9b576a8023bbac764 281 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2 159 2.5E-43 T 01-11-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 AFULGI_00022820 9beef18888372ee9b576a8023bbac764 281 SUPERFAMILY SSF51735 2 160 8.86E-44 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily AFULGI_00022820 9beef18888372ee9b576a8023bbac764 281 PIRSF PIRSF000105 1 281 6.2E-87 T 01-11-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 AFULGI_00022820 9beef18888372ee9b576a8023bbac764 281 SUPERFAMILY SSF48179 163 263 6.55E-22 T 01-11-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AFULGI_00024440 5e99f46739e895547333e8e0304e1202 274 Gene3D G3DSA:3.20.20.70 1 273 3.7E-86 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFULGI_00024440 5e99f46739e895547333e8e0304e1202 274 SUPERFAMILY SSF51412 2 212 1.53E-57 T 01-11-2018 AFULGI_00024440 5e99f46739e895547333e8e0304e1202 274 Pfam PF03060 Nitronate monooxygenase 4 73 5.6E-20 T 01-11-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 AFULGI_00024440 5e99f46739e895547333e8e0304e1202 274 Pfam PF03060 Nitronate monooxygenase 79 240 2.4E-36 T 01-11-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 AFULGI_00020160 fd8272fdcf5400064e833a3f4e2344fe 250 Gene3D G3DSA:3.20.20.140 1 249 6.6E-59 T 01-11-2018 AFULGI_00020160 fd8272fdcf5400064e833a3f4e2344fe 250 SUPERFAMILY SSF51556 1 247 1.84E-31 T 01-11-2018 IPR032466 Metal-dependent hydrolase AFULGI_00020160 fd8272fdcf5400064e833a3f4e2344fe 250 PIRSF PIRSF005295 1 250 4.0E-99 T 01-11-2018 IPR012022 Protein of unknown function UCP005295 AFULGI_00020160 fd8272fdcf5400064e833a3f4e2344fe 250 Pfam PF01026 TatD related DNase 3 246 1.5E-18 T 01-11-2018 IPR001130 TatD family GO:0016788 AFULGI_00008020 1956a642f8a8a31314519f3060de9c0b 197 SUPERFAMILY SSF53790 1 182 1.44E-37 T 01-11-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 AFULGI_00008020 1956a642f8a8a31314519f3060de9c0b 197 Gene3D G3DSA:3.40.1010.10 1 102 7.6E-25 T 01-11-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 AFULGI_00008020 1956a642f8a8a31314519f3060de9c0b 197 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 1 178 3.6E-24 T 01-11-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 AFULGI_00008020 1956a642f8a8a31314519f3060de9c0b 197 TIGRFAM TIGR02467 CbiE: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit 4 182 6.9E-32 T 01-11-2018 IPR012818 Cobalamin (vitamin B12) biosynthesis CbiE, precorrin-6Y methyltransferase GO:0008276|GO:0009236 AFULGI_00008020 1956a642f8a8a31314519f3060de9c0b 197 Gene3D G3DSA:3.30.950.10 103 197 2.3E-48 T 01-11-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 AFULGI_00013420 ed77cecb4f86ecf5a9270ee79b03d9ae 156 Pfam PF02080 TrkA-C domain 90 154 8.8E-17 T 01-11-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 AFULGI_00013420 ed77cecb4f86ecf5a9270ee79b03d9ae 156 PIRSF PIRSF005028 1 156 1.3E-48 T 01-11-2018 IPR026278 Potassium/proton antiporter subunit KhtT AFULGI_00013420 ed77cecb4f86ecf5a9270ee79b03d9ae 156 SUPERFAMILY SSF116726 82 154 1.57E-18 T 01-11-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 AFULGI_00013420 ed77cecb4f86ecf5a9270ee79b03d9ae 156 Gene3D G3DSA:3.30.70.1450 83 155 3.3E-21 T 01-11-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 AFULGI_00005220 7347f6a072452a59f3a865c307b64f82 205 Gene3D G3DSA:3.40.50.150 12 198 5.5E-38 T 01-11-2018 AFULGI_00005220 7347f6a072452a59f3a865c307b64f82 205 SUPERFAMILY SSF53335 14 193 4.3E-41 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFULGI_00005220 7347f6a072452a59f3a865c307b64f82 205 Pfam PF08241 Methyltransferase domain 50 143 7.2E-23 T 01-11-2018 IPR013216 Methyltransferase type 11 GO:0008168 AFULGI_00003840 5f78365039dc8dd51f9ac03999f4913a 117 Pfam PF01986 Domain of unknown function DUF123 25 106 1.1E-22 T 01-11-2018 IPR002837 Protein of unknown function DUF123 AFULGI_00003840 5f78365039dc8dd51f9ac03999f4913a 117 SMART SM00465 18 108 2.7E-13 T 01-11-2018 IPR000305 GIY-YIG endonuclease AFULGI_00003800 9fc972d4ba47889dbebfbca7c4b5e3c2 868 Gene3D G3DSA:2.60.40.3390 780 867 1.2E-34 T 01-11-2018 AFULGI_00003800 9fc972d4ba47889dbebfbca7c4b5e3c2 868 TIGRFAM TIGR04154 archaeo_STT3: oligosaccharyl transferase, archaeosortase A system-associated 15 861 1.2E-250 T 01-11-2018 IPR026410 Oligosaccharyl transferase, archaeal MetaCyc: PWY-7658|MetaCyc: PWY-7661 AFULGI_00003800 9fc972d4ba47889dbebfbca7c4b5e3c2 868 Pfam PF02516 Oligosaccharyl transferase STT3 subunit 18 493 6.2E-118 T 01-11-2018 IPR003674 Oligosaccharyl transferase, STT3 subunit GO:0004576|GO:0006486|GO:0016020 AFULGI_00003800 9fc972d4ba47889dbebfbca7c4b5e3c2 868 Gene3D G3DSA:3.40.50.12610 499 699 3.3E-194 T 01-11-2018 AFULGI_00003800 9fc972d4ba47889dbebfbca7c4b5e3c2 868 Gene3D G3DSA:1.20.58.1650 640 770 3.3E-194 T 01-11-2018 AFULGI_00001520 df1a6768e23c06916419f97ffc6dd258 274 Pfam PF03239 Iron permease FTR1 family 1 262 3.2E-66 T 01-11-2018 IPR004923 Iron permease FTR1/Fip1/EfeU GO:0005381|GO:0016020|GO:0033573|GO:0034755 AFULGI_00001520 df1a6768e23c06916419f97ffc6dd258 274 TIGRFAM TIGR00145 TIGR00145: FTR1 family protein 1 271 3.7E-101 T 01-11-2018 IPR005217 Iron permease FTR1-like GO:0005381|GO:0005886|GO:0033573|GO:0034755 AFULGI_00024180 7eb4f4a6303320f42ddee5dee36ae31d 290 SUPERFAMILY SSF56281 8 276 8.52E-35 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFULGI_00024180 7eb4f4a6303320f42ddee5dee36ae31d 290 Pfam PF00753 Metallo-beta-lactamase superfamily 15 198 8.2E-18 T 01-11-2018 IPR001279 Metallo-beta-lactamase AFULGI_00024180 7eb4f4a6303320f42ddee5dee36ae31d 290 Gene3D G3DSA:3.60.15.10 1 225 2.6E-38 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFULGI_00024180 7eb4f4a6303320f42ddee5dee36ae31d 290 SMART SM00849 17 198 5.9E-18 T 01-11-2018 IPR001279 Metallo-beta-lactamase AFULGI_00019280 f79d324f073b8ff54356d393e2220f7e 391 Pfam PF03283 Pectinacetylesterase 83 245 5.9E-12 T 01-11-2018 IPR004963 Pectinacetylesterase/NOTUM GO:0016787 Reactome: R-HSA-381426|Reactome: R-HSA-5362798|Reactome: R-HSA-8957275 AFULGI_00019280 f79d324f073b8ff54356d393e2220f7e 391 SUPERFAMILY SSF53474 132 297 1.46E-10 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold AFULGI_00019280 f79d324f073b8ff54356d393e2220f7e 391 Gene3D G3DSA:3.40.50.1820 74 284 7.8E-8 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold AFULGI_00004250 2bdaea8acd85011306579f67724edc41 171 Pfam PF09824 ArsR transcriptional regulator 8 166 5.8E-64 T 01-11-2018 IPR014517 ArsR transcriptional regulator AFULGI_00004250 2bdaea8acd85011306579f67724edc41 171 PIRSF PIRSF022057 1 171 1.1E-84 T 01-11-2018 IPR014517 ArsR transcriptional regulator AFULGI_00004250 2bdaea8acd85011306579f67724edc41 171 SUPERFAMILY SSF46785 14 127 2.95E-7 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00002690 cacb259344a745be6e283b9ad5b0267a 354 Gene3D G3DSA:3.30.9.10 81 301 9.0E-91 T 01-11-2018 AFULGI_00002690 cacb259344a745be6e283b9ad5b0267a 354 SUPERFAMILY SSF51905 1 346 2.33E-50 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFULGI_00002690 cacb259344a745be6e283b9ad5b0267a 354 Pfam PF01266 FAD dependent oxidoreductase 2 340 1.7E-61 T 01-11-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 AFULGI_00002690 cacb259344a745be6e283b9ad5b0267a 354 Gene3D G3DSA:3.50.50.60 3 344 9.0E-91 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFULGI_00002690 cacb259344a745be6e283b9ad5b0267a 354 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 187 202 5.2E-6 T 01-11-2018 AFULGI_00002690 cacb259344a745be6e283b9ad5b0267a 354 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 5.2E-6 T 01-11-2018 AFULGI_00000800 e9f3ebf2842468e2c0366df8e9b239d8 106 Pfam PF01402 Ribbon-helix-helix protein, copG family 14 41 1.9E-4 T 01-11-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 AFULGI_00003850 7ea9f63bee5d29a69153089e2212bd88 313 Pfam PF04473 Transglutaminase-like domain 51 198 1.4E-52 T 01-11-2018 IPR007562 Transglutaminase-like domain AFULGI_00003850 7ea9f63bee5d29a69153089e2212bd88 313 Gene3D G3DSA:3.10.620.30 41 176 7.5E-8 T 01-11-2018 AFULGI_00003850 7ea9f63bee5d29a69153089e2212bd88 313 SUPERFAMILY SSF54001 105 171 1.0E-4 T 01-11-2018 IPR038765 Papain-like cysteine peptidase superfamily AFULGI_00005980 cf4a574eede36eae4835d2ff7fb8e12f 778 SUPERFAMILY SSF52402 111 299 1.42E-33 T 01-11-2018 AFULGI_00005980 cf4a574eede36eae4835d2ff7fb8e12f 778 Gene3D G3DSA:3.30.70.20 445 508 6.0E-9 T 01-11-2018 AFULGI_00005980 cf4a574eede36eae4835d2ff7fb8e12f 778 Gene3D G3DSA:3.40.50.620 100 318 6.8E-48 T 01-11-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFULGI_00005980 cf4a574eede36eae4835d2ff7fb8e12f 778 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 456 467 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFULGI_00005980 cf4a574eede36eae4835d2ff7fb8e12f 778 SUPERFAMILY SSF54862 439 493 1.23E-10 T 01-11-2018 AFULGI_00005980 cf4a574eede36eae4835d2ff7fb8e12f 778 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 132 309 2.0E-34 T 01-11-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 AFULGI_00000270 4809b09bc6731874abeee12866a4cc18 114 Gene3D G3DSA:3.40.1230.10 1 114 1.6E-33 T 01-11-2018 IPR036748 MTH938-like superfamily AFULGI_00000270 4809b09bc6731874abeee12866a4cc18 114 Pfam PF04430 Protein of unknown function (DUF498/DUF598) 3 109 4.8E-23 T 01-11-2018 IPR007523 NDUFAF3/Mth938 domain-containing protein AFULGI_00000270 4809b09bc6731874abeee12866a4cc18 114 SUPERFAMILY SSF64076 1 114 3.01E-29 T 01-11-2018 IPR036748 MTH938-like superfamily AFULGI_00010660 ac5a183befb33bd2c60263f19ac6f628 551 Pfam PF13193 AMP-binding enzyme C-terminal domain 460 541 1.3E-19 T 01-11-2018 IPR025110 AMP-binding enzyme, C-terminal domain AFULGI_00010660 ac5a183befb33bd2c60263f19ac6f628 551 Gene3D G3DSA:3.40.50.12780 28 444 6.8E-102 T 01-11-2018 AFULGI_00010660 ac5a183befb33bd2c60263f19ac6f628 551 Pfam PF00501 AMP-binding enzyme 46 451 4.4E-94 T 01-11-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFULGI_00010660 ac5a183befb33bd2c60263f19ac6f628 551 Gene3D G3DSA:3.30.300.30 447 551 2.5E-26 T 01-11-2018 AFULGI_00010660 ac5a183befb33bd2c60263f19ac6f628 551 ProSitePatterns PS00455 Putative AMP-binding domain signature. 196 207 - T 01-11-2018 IPR020845 AMP-binding, conserved site AFULGI_00010660 ac5a183befb33bd2c60263f19ac6f628 551 SUPERFAMILY SSF56801 29 549 2.75E-135 T 01-11-2018 AFULGI_00023980 1841a4baacc940c2355f39e60dbd2eee 143 Gene3D G3DSA:3.40.50.960 1 139 3.5E-32 T 01-11-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AFULGI_00023980 1841a4baacc940c2355f39e60dbd2eee 143 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 1 138 21.626 T 01-11-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AFULGI_00023980 1841a4baacc940c2355f39e60dbd2eee 143 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 4 134 4.0E-34 T 01-11-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AFULGI_00023980 1841a4baacc940c2355f39e60dbd2eee 143 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 4 137 1.9E-52 T 01-11-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AFULGI_00023980 1841a4baacc940c2355f39e60dbd2eee 143 SUPERFAMILY SSF52121 2 138 1.96E-41 T 01-11-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AFULGI_00018330 a99dcbfd8cd2217e06a57db265b14132 72 Gene3D G3DSA:2.60.120.10 3 66 4.2E-9 T 01-11-2018 IPR014710 RmlC-like jelly roll fold AFULGI_00018330 a99dcbfd8cd2217e06a57db265b14132 72 Pfam PF07883 Cupin domain 7 62 2.0E-7 T 01-11-2018 IPR013096 Cupin 2, conserved barrel AFULGI_00018330 a99dcbfd8cd2217e06a57db265b14132 72 SUPERFAMILY SSF51182 14 66 2.55E-9 T 01-11-2018 IPR011051 RmlC-like cupin domain superfamily AFULGI_00019480 995465403fcff0ac7f132fa8ff1e3910 191 TIGRFAM TIGR02175 PorC_KorC: 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family 5 187 2.1E-76 T 01-11-2018 IPR011894 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0055114 AFULGI_00019480 995465403fcff0ac7f132fa8ff1e3910 191 SUPERFAMILY SSF53323 6 189 1.44E-52 T 01-11-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 AFULGI_00019480 995465403fcff0ac7f132fa8ff1e3910 191 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 14 183 3.7E-42 T 01-11-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 AFULGI_00019480 995465403fcff0ac7f132fa8ff1e3910 191 Gene3D G3DSA:3.40.920.10 3 188 4.2E-60 T 01-11-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 AFULGI_00020470 f79737f93734165617d86dbfc5861fa9 183 Pfam PF01380 SIS domain 31 133 1.3E-19 T 01-11-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 AFULGI_00020470 f79737f93734165617d86dbfc5861fa9 183 SUPERFAMILY SSF53697 1 181 1.5E-42 T 01-11-2018 AFULGI_00020470 f79737f93734165617d86dbfc5861fa9 183 Gene3D G3DSA:3.40.50.10490 1 183 3.3E-64 T 01-11-2018 AFULGI_00020470 f79737f93734165617d86dbfc5861fa9 183 TIGRFAM TIGR03127 RuMP_HxlB: 6-phospho 3-hexuloisomerase 6 183 5.3E-67 T 01-11-2018 IPR017552 3-hexulose-6-phosphate isomerase GO:0016853 AFULGI_00021640 0b620643fb2c47bdcc0a5e023f511098 198 SUPERFAMILY SSF54768 40 111 6.91E-22 T 01-11-2018 AFULGI_00021640 0b620643fb2c47bdcc0a5e023f511098 198 Pfam PF00333 Ribosomal protein S5, N-terminal domain 46 110 5.1E-26 T 01-11-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 AFULGI_00021640 0b620643fb2c47bdcc0a5e023f511098 198 Pfam PF03719 Ribosomal protein S5, C-terminal domain 131 194 1.7E-21 T 01-11-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 AFULGI_00021640 0b620643fb2c47bdcc0a5e023f511098 198 Gene3D G3DSA:3.30.230.10 109 197 1.3E-31 T 01-11-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AFULGI_00021640 0b620643fb2c47bdcc0a5e023f511098 198 ProSitePatterns PS00585 Ribosomal protein S5 signature. 63 95 - T 01-11-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site AFULGI_00021640 0b620643fb2c47bdcc0a5e023f511098 198 SUPERFAMILY SSF54211 124 196 1.77E-20 T 01-11-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFULGI_00021640 0b620643fb2c47bdcc0a5e023f511098 198 Hamap MF_01307_A 30S ribosomal protein S5 [rpsE]. 1 198 49.982 T 01-11-2018 IPR005711 Ribosomal protein S5, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-3214858|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8876725|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00021640 0b620643fb2c47bdcc0a5e023f511098 198 TIGRFAM TIGR01020 uS5_euk_arch: ribosomal protein uS5 2 197 4.6E-106 T 01-11-2018 IPR005711 Ribosomal protein S5, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-3214858|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8876725|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00021640 0b620643fb2c47bdcc0a5e023f511098 198 Gene3D G3DSA:3.30.160.770 4 107 3.2E-41 T 01-11-2018 AFULGI_00015660 14bf0ccdc943cf68e6c95529cae1a207 545 ProSitePatterns PS00750 Chaperonins TCP-1 signature 1. 40 52 - T 01-11-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 AFULGI_00015660 14bf0ccdc943cf68e6c95529cae1a207 545 ProSitePatterns PS00751 Chaperonins TCP-1 signature 2. 61 77 - T 01-11-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 AFULGI_00015660 14bf0ccdc943cf68e6c95529cae1a207 545 ProSitePatterns PS00995 Chaperonins TCP-1 signature 3. 89 97 - T 01-11-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 AFULGI_00015660 14bf0ccdc943cf68e6c95529cae1a207 545 SUPERFAMILY SSF54849 150 405 4.27E-28 T 01-11-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily AFULGI_00015660 14bf0ccdc943cf68e6c95529cae1a207 545 SUPERFAMILY SSF52029 212 378 7.74E-62 T 01-11-2018 IPR027409 GroEL-like apical domain superfamily AFULGI_00015660 14bf0ccdc943cf68e6c95529cae1a207 545 Gene3D G3DSA:1.10.560.10 28 522 2.1E-211 T 01-11-2018 IPR027413 GroEL-like equatorial domain superfamily AFULGI_00015660 14bf0ccdc943cf68e6c95529cae1a207 545 Gene3D G3DSA:3.50.7.10 218 369 2.1E-211 T 01-11-2018 IPR027409 GroEL-like apical domain superfamily AFULGI_00015660 14bf0ccdc943cf68e6c95529cae1a207 545 Gene3D G3DSA:3.30.260.10 147 405 2.1E-211 T 01-11-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily AFULGI_00015660 14bf0ccdc943cf68e6c95529cae1a207 545 SUPERFAMILY SSF48592 17 524 2.88E-97 T 01-11-2018 IPR027413 GroEL-like equatorial domain superfamily AFULGI_00015660 14bf0ccdc943cf68e6c95529cae1a207 545 Pfam PF00118 TCP-1/cpn60 chaperonin family 35 525 3.8E-188 T 01-11-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 AFULGI_00015660 14bf0ccdc943cf68e6c95529cae1a207 545 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 37 53 1.7E-35 T 01-11-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 AFULGI_00015660 14bf0ccdc943cf68e6c95529cae1a207 545 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 373 395 1.7E-35 T 01-11-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 AFULGI_00015660 14bf0ccdc943cf68e6c95529cae1a207 545 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 89 108 1.7E-35 T 01-11-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 AFULGI_00015660 14bf0ccdc943cf68e6c95529cae1a207 545 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 407 419 1.7E-35 T 01-11-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 AFULGI_00015660 14bf0ccdc943cf68e6c95529cae1a207 545 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 59 77 1.7E-35 T 01-11-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 AFULGI_00015660 14bf0ccdc943cf68e6c95529cae1a207 545 TIGRFAM TIGR02339 thermosome_arch: thermosome, various subunits, archaeal 8 525 5.9E-249 T 01-11-2018 IPR012714 Thermosome, archaeal GO:0005524|GO:0006457|GO:0051082 AFULGI_00024470 7494c9deb6f7961390b2e9ef77231934 291 TIGRFAM TIGR01475 ubiA_other: putative 4-hydroxybenzoate polyprenyltransferase 3 287 4.4E-116 T 01-11-2018 IPR006371 4-hydroxybenzoate polyprenyltransferase-related AFULGI_00024470 7494c9deb6f7961390b2e9ef77231934 291 Gene3D G3DSA:1.20.120.1780 166 291 4.1E-31 T 01-11-2018 AFULGI_00024470 7494c9deb6f7961390b2e9ef77231934 291 Gene3D G3DSA:1.10.357.140 10 165 8.8E-53 T 01-11-2018 AFULGI_00024470 7494c9deb6f7961390b2e9ef77231934 291 Pfam PF01040 UbiA prenyltransferase family 19 268 7.6E-47 T 01-11-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 AFULGI_00008180 b2ca8b3878e58d81dd384278d7ba81a4 67 Gene3D G3DSA:3.10.20.630 1 67 2.1E-23 T 01-11-2018 AFULGI_00008180 b2ca8b3878e58d81dd384278d7ba81a4 67 SUPERFAMILY SSF54285 10 67 1.98E-7 T 01-11-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp AFULGI_00003830 fd0651207cdc458177f05714fa542820 214 Gene3D G3DSA:2.40.50.140 128 214 9.1E-7 T 01-11-2018 AFULGI_00003830 fd0651207cdc458177f05714fa542820 214 SUPERFAMILY SSF50249 23 126 4.86E-11 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold AFULGI_00003830 fd0651207cdc458177f05714fa542820 214 Gene3D G3DSA:2.40.50.140 31 126 2.0E-13 T 01-11-2018 AFULGI_00003830 fd0651207cdc458177f05714fa542820 214 SUPERFAMILY SSF50249 129 208 1.05E-7 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold AFULGI_00000880 93394ad74cc7660811e7853290ed4dfe 293 Gene3D G3DSA:3.60.15.10 2 229 1.8E-41 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFULGI_00000880 93394ad74cc7660811e7853290ed4dfe 293 Pfam PF00753 Metallo-beta-lactamase superfamily 23 203 4.6E-22 T 01-11-2018 IPR001279 Metallo-beta-lactamase AFULGI_00000880 93394ad74cc7660811e7853290ed4dfe 293 SMART SM00849 24 203 2.7E-24 T 01-11-2018 IPR001279 Metallo-beta-lactamase AFULGI_00000880 93394ad74cc7660811e7853290ed4dfe 293 SUPERFAMILY SSF56281 2 261 6.3E-49 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFULGI_00002090 16b0a87be9eb0f3aff1ba926ae63d4ea 419 Pfam PF13458 Periplasmic binding protein 32 396 2.5E-41 T 01-11-2018 IPR028081 Leucine-binding protein domain AFULGI_00002090 16b0a87be9eb0f3aff1ba926ae63d4ea 419 SUPERFAMILY SSF53822 32 407 6.06E-57 T 01-11-2018 IPR028082 Periplasmic binding protein-like I AFULGI_00002090 16b0a87be9eb0f3aff1ba926ae63d4ea 419 Gene3D G3DSA:3.40.50.2300 32 387 4.8E-68 T 01-11-2018 AFULGI_00002090 16b0a87be9eb0f3aff1ba926ae63d4ea 419 Gene3D G3DSA:3.40.50.2300 157 416 4.8E-68 T 01-11-2018 AFULGI_00001370 7ba6d3cbd5633d6a4694884e513e40e6 164 SUPERFAMILY SSF46785 91 155 5.82E-14 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00001370 7ba6d3cbd5633d6a4694884e513e40e6 164 Gene3D G3DSA:1.10.10.10 76 160 3.0E-10 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00001370 7ba6d3cbd5633d6a4694884e513e40e6 164 Pfam PF01047 MarR family 99 149 3.0E-6 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFULGI_00004980 f46af489aa3878d779a6fe476bd1c163 246 SMART SM00948 8 30 2.7E-11 T 01-11-2018 IPR000426 Proteasome alpha-subunit, N-terminal domain GO:0004175|GO:0006511|GO:0019773 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 AFULGI_00004980 f46af489aa3878d779a6fe476bd1c163 246 Pfam PF10584 Proteasome subunit A N-terminal signature 8 30 3.8E-14 T 01-11-2018 IPR000426 Proteasome alpha-subunit, N-terminal domain GO:0004175|GO:0006511|GO:0019773 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 AFULGI_00004980 f46af489aa3878d779a6fe476bd1c163 246 TIGRFAM TIGR03633 arc_protsome_A: proteasome endopeptidase complex, archaeal, alpha subunit 6 234 1.5E-112 T 01-11-2018 IPR019982 Proteasome alpha subunit, archaeal GO:0004298|GO:0005839|GO:0051603 AFULGI_00004980 f46af489aa3878d779a6fe476bd1c163 246 Gene3D G3DSA:3.60.20.10 1 246 1.5E-92 T 01-11-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFULGI_00004980 f46af489aa3878d779a6fe476bd1c163 246 ProSitePatterns PS00388 Proteasome alpha-type subunits signature. 8 30 - T 01-11-2018 IPR000426 Proteasome alpha-subunit, N-terminal domain GO:0004175|GO:0006511|GO:0019773 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 AFULGI_00004980 f46af489aa3878d779a6fe476bd1c163 246 Hamap MF_00289_A Proteasome subunit alpha [prcA]. 3 233 49.581 T 01-11-2018 IPR019982 Proteasome alpha subunit, archaeal GO:0004298|GO:0005839|GO:0051603 AFULGI_00004980 f46af489aa3878d779a6fe476bd1c163 246 Pfam PF00227 Proteasome subunit 31 214 1.6E-63 T 01-11-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 AFULGI_00004980 f46af489aa3878d779a6fe476bd1c163 246 SUPERFAMILY SSF56235 6 238 5.9E-83 T 01-11-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFULGI_00000850 d3b8c70b2a7c0e3b8143b8a55ea4de84 300 Gene3D G3DSA:3.40.190.10 19 123 6.4E-18 T 01-11-2018 AFULGI_00000850 d3b8c70b2a7c0e3b8143b8a55ea4de84 300 SMART SM00062 24 245 1.2E-28 T 01-11-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF AFULGI_00000850 d3b8c70b2a7c0e3b8143b8a55ea4de84 300 SUPERFAMILY SSF53850 22 241 1.68E-40 T 01-11-2018 AFULGI_00000850 d3b8c70b2a7c0e3b8143b8a55ea4de84 300 Gene3D G3DSA:3.40.190.10 134 300 8.7E-19 T 01-11-2018 AFULGI_00000850 d3b8c70b2a7c0e3b8143b8a55ea4de84 300 Pfam PF03180 NLPA lipoprotein 25 248 4.1E-40 T 01-11-2018 IPR004872 Lipoprotein NlpA family AFULGI_00023290 848d64f8decfd1bf606fd0f785110ca0 206 Pfam PF01983 Guanylyl transferase CofC like 1 205 1.8E-95 T 01-11-2018 IPR002835 2-phospho-L-lactate guanylyltransferase, CofC GO:0016779 KEGG: 00680+2.7.7.68|MetaCyc: PWY-5198 AFULGI_00023290 848d64f8decfd1bf606fd0f785110ca0 206 Gene3D G3DSA:3.90.550.10 1 157 5.4E-33 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFULGI_00023290 848d64f8decfd1bf606fd0f785110ca0 206 TIGRFAM TIGR03552 F420_cofC: 2-phospho-L-lactate guanylyltransferase 2 178 3.1E-55 T 01-11-2018 IPR002835 2-phospho-L-lactate guanylyltransferase, CofC GO:0016779 KEGG: 00680+2.7.7.68|MetaCyc: PWY-5198 AFULGI_00023290 848d64f8decfd1bf606fd0f785110ca0 206 Hamap MF_02114 2-phospho-L-lactate guanylyltransferase [cofC]. 1 186 26.805 T 01-11-2018 IPR002835 2-phospho-L-lactate guanylyltransferase, CofC GO:0016779 KEGG: 00680+2.7.7.68|MetaCyc: PWY-5198 AFULGI_00023290 848d64f8decfd1bf606fd0f785110ca0 206 SUPERFAMILY SSF53448 2 192 2.18E-34 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFULGI_00012260 a5522d9b693d1b099183b1f360e855c0 156 TIGRFAM TIGR01077 L13_A_E: ribosomal protein uL13 17 154 1.5E-65 T 01-11-2018 IPR005755 Ribosomal protein L13, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 AFULGI_00012260 a5522d9b693d1b099183b1f360e855c0 156 SUPERFAMILY SSF52161 14 153 9.55E-42 T 01-11-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 AFULGI_00012260 a5522d9b693d1b099183b1f360e855c0 156 ProSitePatterns PS00783 Ribosomal protein L13 signature. 91 114 - T 01-11-2018 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 AFULGI_00012260 a5522d9b693d1b099183b1f360e855c0 156 PIRSF PIRSF002181 1 156 7.8E-45 T 01-11-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 AFULGI_00012260 a5522d9b693d1b099183b1f360e855c0 156 Pfam PF00572 Ribosomal protein L13 16 115 3.6E-12 T 01-11-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 AFULGI_00012260 a5522d9b693d1b099183b1f360e855c0 156 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 16 145 21.693 T 01-11-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 AFULGI_00012260 a5522d9b693d1b099183b1f360e855c0 156 Gene3D G3DSA:3.90.1180.10 9 155 5.2E-53 T 01-11-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 AFULGI_00024950 63dee3ee26d5b1fa8b7121f5004777f0 141 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 7 140 3.0E-62 T 01-11-2018 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 AFULGI_00024950 63dee3ee26d5b1fa8b7121f5004777f0 141 Pfam PF02310 B12 binding domain 9 123 8.4E-24 T 01-11-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 AFULGI_00024950 63dee3ee26d5b1fa8b7121f5004777f0 141 Gene3D G3DSA:3.40.50.280 1 141 3.4E-60 T 01-11-2018 AFULGI_00024950 63dee3ee26d5b1fa8b7121f5004777f0 141 SUPERFAMILY SSF52242 3 135 9.55E-51 T 01-11-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 AFULGI_00018540 1eb70e54c35bad416b7ffb7011e1aa90 320 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 4 316 31.806 T 01-11-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 AFULGI_00018540 1eb70e54c35bad416b7ffb7011e1aa90 320 Pfam PF00591 Glycosyl transferase family, a/b domain 63 305 1.3E-73 T 01-11-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 AFULGI_00018540 1eb70e54c35bad416b7ffb7011e1aa90 320 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 8 314 4.6E-96 T 01-11-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 AFULGI_00018540 1eb70e54c35bad416b7ffb7011e1aa90 320 Gene3D G3DSA:1.20.970.10 10 171 7.3E-90 T 01-11-2018 AFULGI_00018540 1eb70e54c35bad416b7ffb7011e1aa90 320 SUPERFAMILY SSF52418 63 313 3.53E-68 T 01-11-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 AFULGI_00018540 1eb70e54c35bad416b7ffb7011e1aa90 320 Pfam PF02885 Glycosyl transferase family, helical bundle domain 23 56 1.8E-4 T 01-11-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 AFULGI_00018540 1eb70e54c35bad416b7ffb7011e1aa90 320 Gene3D G3DSA:3.40.1030.10 62 296 7.3E-90 T 01-11-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 AFULGI_00007240 7e645c693337ecadf914bc0a1ae6da1a 128 PIRSF PIRSF003025 1 128 1.9E-49 T 01-11-2018 IPR001884 Translation elongation factor IF5A-like GO:0003723|GO:0003746|GO:0043022|GO:0045901 AFULGI_00007240 7e645c693337ecadf914bc0a1ae6da1a 128 Pfam PF01287 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold 68 124 2.1E-8 T 01-11-2018 IPR020189 Translation elongation factor, IF5A C-terminal GO:0003723|GO:0003746|GO:0006452|GO:0043022|GO:0045901|GO:0045905 AFULGI_00007240 7e645c693337ecadf914bc0a1ae6da1a 128 ProSitePatterns PS00302 Eukaryotic initiation factor 5A hypusine signature. 33 40 - T 01-11-2018 IPR019769 Translation elongation factor, IF5A, hypusine site GO:0003723|GO:0003746|GO:0043022|GO:0045901|GO:0045905 AFULGI_00007240 7e645c693337ecadf914bc0a1ae6da1a 128 TIGRFAM TIGR00037 eIF_5A: translation elongation factor IF5A 1 127 2.4E-64 T 01-11-2018 IPR001884 Translation elongation factor IF5A-like GO:0003723|GO:0003746|GO:0043022|GO:0045901 AFULGI_00007240 7e645c693337ecadf914bc0a1ae6da1a 128 SUPERFAMILY SSF50104 4 76 4.41E-21 T 01-11-2018 IPR008991 Translation protein SH3-like domain superfamily AFULGI_00007240 7e645c693337ecadf914bc0a1ae6da1a 128 Gene3D G3DSA:2.30.30.30 1 68 4.4E-28 T 01-11-2018 IPR014722 Ribosomal protein L2, domain 2 AFULGI_00007240 7e645c693337ecadf914bc0a1ae6da1a 128 Hamap MF_00085 Translation initiation factor 5A [eif5a]. 1 127 37.085 T 01-11-2018 IPR022847 Translation elongation factor IF5A, archaeal AFULGI_00007240 7e645c693337ecadf914bc0a1ae6da1a 128 SMART SM01376 68 128 2.4E-19 T 01-11-2018 IPR020189 Translation elongation factor, IF5A C-terminal GO:0003723|GO:0003746|GO:0006452|GO:0043022|GO:0045901|GO:0045905 AFULGI_00007240 7e645c693337ecadf914bc0a1ae6da1a 128 SUPERFAMILY SSF50249 68 124 4.24E-12 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold AFULGI_00007240 7e645c693337ecadf914bc0a1ae6da1a 128 Gene3D G3DSA:2.40.50.140 69 128 1.0E-24 T 01-11-2018 AFULGI_00004920 2108f36a6ba025c3ef75fd1dd101e6b3 378 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 3 176 8.2E-33 T 01-11-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AFULGI_00004920 2108f36a6ba025c3ef75fd1dd101e6b3 378 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 183 376 36.782 T 01-11-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 AFULGI_00004920 2108f36a6ba025c3ef75fd1dd101e6b3 378 TIGRFAM TIGR00505 ribA: GTP cyclohydrolase II 186 374 2.2E-85 T 01-11-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 AFULGI_00004920 2108f36a6ba025c3ef75fd1dd101e6b3 378 Gene3D G3DSA:3.40.50.10990 185 354 5.0E-66 T 01-11-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 AFULGI_00004920 2108f36a6ba025c3ef75fd1dd101e6b3 378 PIRSF PIRSF001259 1 378 4.5E-107 T 01-11-2018 AFULGI_00004920 2108f36a6ba025c3ef75fd1dd101e6b3 378 Pfam PF00925 GTP cyclohydrolase II 187 348 2.1E-65 T 01-11-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 AFULGI_00004920 2108f36a6ba025c3ef75fd1dd101e6b3 378 SUPERFAMILY SSF55821 2 185 1.99E-36 T 01-11-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily AFULGI_00004920 2108f36a6ba025c3ef75fd1dd101e6b3 378 SUPERFAMILY SSF142695 183 348 5.23E-58 T 01-11-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 AFULGI_00004920 2108f36a6ba025c3ef75fd1dd101e6b3 378 Gene3D G3DSA:3.90.870.10 1 184 1.0E-30 T 01-11-2018 AFULGI_00023580 9cf0ea4009c37f1f85362c9ae1721018 313 PIRSF PIRSF004884 1 313 1.1E-128 T 01-11-2018 IPR004422 GHMP kinase group 1 KEGG: 00790+2.4.2.54|MetaCyc: PWY-6148 AFULGI_00023580 9cf0ea4009c37f1f85362c9ae1721018 313 TIGRFAM TIGR00144 beta_RFAP_syn: beta-ribofuranosylaminobenzene 5'-phosphate synthase family 2 312 4.9E-168 T 01-11-2018 IPR004422 GHMP kinase group 1 KEGG: 00790+2.4.2.54|MetaCyc: PWY-6148 AFULGI_00023580 9cf0ea4009c37f1f85362c9ae1721018 313 SUPERFAMILY SSF54211 3 141 3.87E-17 T 01-11-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFULGI_00023580 9cf0ea4009c37f1f85362c9ae1721018 313 Pfam PF00288 GHMP kinases N terminal domain 76 136 2.3E-7 T 01-11-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 AFULGI_00023580 9cf0ea4009c37f1f85362c9ae1721018 313 Gene3D G3DSA:3.30.230.10 21 145 1.5E-8 T 01-11-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AFULGI_00019150 acabc9abd768cce1a8dd0f195d368e8c 222 Gene3D G3DSA:3.40.50.620 1 121 6.8E-37 T 01-11-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFULGI_00019150 acabc9abd768cce1a8dd0f195d368e8c 222 SUPERFAMILY SSF52402 1 217 4.19E-67 T 01-11-2018 AFULGI_00019150 acabc9abd768cce1a8dd0f195d368e8c 222 TIGRFAM TIGR00290 MJ0570_dom: MJ0570-related uncharacterized domain 1 222 4.1E-102 T 01-11-2018 IPR002761 Diphthamide synthase domain MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 AFULGI_00019150 acabc9abd768cce1a8dd0f195d368e8c 222 Pfam PF01902 Diphthamide synthase 1 217 5.6E-107 T 01-11-2018 IPR002761 Diphthamide synthase domain MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 AFULGI_00019150 acabc9abd768cce1a8dd0f195d368e8c 222 TIGRFAM TIGR03679 arCOG00187: arCOG00187 universal archaeal metal-binding-domain/4Fe-4S-binding-domain containing ABC transporter, ATP-binding protein 4 215 5.2E-84 T 01-11-2018 IPR022427 Uncharacterised protein MJ0570, ATP-binding AFULGI_00019150 acabc9abd768cce1a8dd0f195d368e8c 222 TIGRFAM TIGR00289 TIGR00289: TIGR00289 family protein 1 222 2.1E-119 T 01-11-2018 IPR005237 Uncharacterised protein MJ0570 AFULGI_00019150 acabc9abd768cce1a8dd0f195d368e8c 222 PIRSF PIRSF039123 1 222 8.0E-82 T 01-11-2018 IPR030662 Diphthine--ammonia ligase/Uncharacterised protein MJ0570 MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 AFULGI_00019150 acabc9abd768cce1a8dd0f195d368e8c 222 Gene3D G3DSA:3.90.1490.10 122 220 2.5E-31 T 01-11-2018 AFULGI_00009530 50593d4e96cf6309908265ef72bb01b0 447 Gene3D G3DSA:3.40.462.40 260 402 1.2E-20 T 01-11-2018 AFULGI_00009530 50593d4e96cf6309908265ef72bb01b0 447 Gene3D G3DSA:3.30.465.40 22 237 7.0E-64 T 01-11-2018 AFULGI_00009530 50593d4e96cf6309908265ef72bb01b0 447 SUPERFAMILY SSF56176 18 222 4.67E-53 T 01-11-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 AFULGI_00009530 50593d4e96cf6309908265ef72bb01b0 447 Pfam PF01565 FAD binding domain 49 185 1.8E-39 T 01-11-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 AFULGI_00009530 50593d4e96cf6309908265ef72bb01b0 447 SUPERFAMILY SSF55103 227 447 1.08E-22 T 01-11-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 AFULGI_00009530 50593d4e96cf6309908265ef72bb01b0 447 Pfam PF02913 FAD linked oxidases, C-terminal domain 222 444 1.3E-21 T 01-11-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 AFULGI_00013730 90490d14400e0af71ff6571c59e63413 81 Pfam PF02514 CobN/Magnesium Chelatase 5 28 4.4E-5 T 01-11-2018 IPR003672 CobN/magnesium chelatase GO:0009058 AFULGI_00008500 59adb420dab680b85acd8633ae28afad 96 Gene3D G3DSA:3.40.30.10 1 86 2.8E-17 T 01-11-2018 AFULGI_00008500 59adb420dab680b85acd8633ae28afad 96 SUPERFAMILY SSF52833 4 85 7.02E-20 T 01-11-2018 IPR036249 Thioredoxin-like superfamily AFULGI_00008500 59adb420dab680b85acd8633ae28afad 96 Pfam PF00085 Thioredoxin 5 76 4.2E-13 T 01-11-2018 IPR013766 Thioredoxin domain GO:0045454 AFULGI_00016470 22df6ba0c65a85c3d1674a819223bff6 467 Pfam PF13203 Putative metallopeptidase domain 10 330 1.3E-28 T 01-11-2018 IPR025154 Putative metallopeptidase domain AFULGI_00016470 22df6ba0c65a85c3d1674a819223bff6 467 SUPERFAMILY SSF53300 339 429 2.78E-7 T 01-11-2018 IPR036465 von Willebrand factor A-like domain superfamily AFULGI_00016470 22df6ba0c65a85c3d1674a819223bff6 467 Pfam PF09967 VWA-like domain (DUF2201) 340 464 3.3E-25 T 01-11-2018 IPR018698 VWA-like domain AFULGI_00012370 ed04d20da34a07597a369f62dfc4129c 554 Pfam PF10633 NPCBM-associated, NEW3 domain of alpha-galactosidase 434 507 1.7E-15 T 01-11-2018 IPR018905 Alpha-galactosidase, NEW3 domain AFULGI_00012370 ed04d20da34a07597a369f62dfc4129c 554 Gene3D G3DSA:2.60.40.1120 231 303 6.5E-8 T 01-11-2018 AFULGI_00012370 ed04d20da34a07597a369f62dfc4129c 554 Pfam PF13620 Carboxypeptidase regulatory-like domain 231 299 1.7E-9 T 01-11-2018 AFULGI_00012370 ed04d20da34a07597a369f62dfc4129c 554 SUPERFAMILY SSF49452 227 302 1.29E-7 T 01-11-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 AFULGI_00008470 b5dc6a1a4abcb677ae5f88f5cb7e8097 58 SMART SM00746 6 44 3.3E-14 T 01-11-2018 IPR011017 TRASH domain AFULGI_00008470 b5dc6a1a4abcb677ae5f88f5cb7e8097 58 Gene3D G3DSA:2.30.170.20 4 57 1.7E-27 T 01-11-2018 IPR038630 Ribosomal protein L24e/L24 superfamily AFULGI_00008470 b5dc6a1a4abcb677ae5f88f5cb7e8097 58 Pfam PF01246 Ribosomal protein L24e 1 57 9.8E-26 T 01-11-2018 IPR000988 Ribosomal protein L24e-related AFULGI_00008470 b5dc6a1a4abcb677ae5f88f5cb7e8097 58 Hamap MF_00773 50S ribosomal protein L24e [rpl24e]. 1 55 28.597 T 01-11-2018 IPR023438 Ribosomal protein L24e GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFULGI_00008470 b5dc6a1a4abcb677ae5f88f5cb7e8097 58 SUPERFAMILY SSF57716 4 56 7.98E-21 T 01-11-2018 AFULGI_00008470 b5dc6a1a4abcb677ae5f88f5cb7e8097 58 ProSitePatterns PS01073 Ribosomal protein L24e signature. 8 25 - T 01-11-2018 IPR023442 Ribosomal protein L24e, conserved site AFULGI_00003480 2777f5651b9e8abde7f029cc76179aad 84 Pfam PF00582 Universal stress protein family 21 84 1.5E-12 T 01-11-2018 IPR006016 UspA AFULGI_00003480 2777f5651b9e8abde7f029cc76179aad 84 Gene3D G3DSA:3.40.50.620 17 84 1.7E-17 T 01-11-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFULGI_00003480 2777f5651b9e8abde7f029cc76179aad 84 SUPERFAMILY SSF52402 2 84 7.12E-15 T 01-11-2018 AFULGI_00008250 cc589e8cc01182144f4e506f14204632 521 Pfam PF03144 Elongation factor Tu domain 2 358 428 1.9E-14 T 01-11-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 AFULGI_00008250 cc589e8cc01182144f4e506f14204632 521 Gene3D G3DSA:2.40.30.10 435 521 1.3E-7 T 01-11-2018 AFULGI_00008250 cc589e8cc01182144f4e506f14204632 521 Gene3D G3DSA:3.40.50.300 105 337 3.5E-38 T 01-11-2018 AFULGI_00008250 cc589e8cc01182144f4e506f14204632 521 SUPERFAMILY SSF50465 433 520 3.5E-20 T 01-11-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal AFULGI_00008250 cc589e8cc01182144f4e506f14204632 521 SUPERFAMILY SSF52540 110 359 8.56E-39 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00008250 cc589e8cc01182144f4e506f14204632 521 PRINTS PR00315 GTP-binding elongation factor signature 201 211 8.1E-7 T 01-11-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFULGI_00008250 cc589e8cc01182144f4e506f14204632 521 PRINTS PR00315 GTP-binding elongation factor signature 255 264 8.1E-7 T 01-11-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFULGI_00008250 cc589e8cc01182144f4e506f14204632 521 PRINTS PR00315 GTP-binding elongation factor signature 158 166 8.1E-7 T 01-11-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFULGI_00008250 cc589e8cc01182144f4e506f14204632 521 PRINTS PR00315 GTP-binding elongation factor signature 116 129 8.1E-7 T 01-11-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFULGI_00008250 cc589e8cc01182144f4e506f14204632 521 Pfam PF00009 Elongation factor Tu GTP binding domain 112 335 1.5E-39 T 01-11-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFULGI_00008250 cc589e8cc01182144f4e506f14204632 521 SUPERFAMILY SSF50447 340 431 1.69E-21 T 01-11-2018 IPR009000 Translation protein, beta-barrel domain superfamily AFULGI_00008250 cc589e8cc01182144f4e506f14204632 521 Gene3D G3DSA:2.40.30.10 339 433 1.0E-25 T 01-11-2018 AFULGI_00008250 cc589e8cc01182144f4e506f14204632 521 Pfam PF04326 Putative DNA-binding domain 12 113 3.2E-6 T 01-11-2018 IPR007421 Schlafen, AAA domain GO:0005524 AFULGI_00008250 cc589e8cc01182144f4e506f14204632 521 Pfam PF03143 Elongation factor Tu C-terminal domain 436 509 1.9E-8 T 01-11-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal AFULGI_00007590 27caa445b7478752d96adb27875719d1 134 Pfam PF13358 DDE superfamily endonuclease 3 106 6.4E-23 T 01-11-2018 IPR038717 Tc1-like transposase, DDE domain AFULGI_00007590 27caa445b7478752d96adb27875719d1 134 Gene3D G3DSA:3.30.420.470 6 131 2.0E-17 T 01-11-2018 AFULGI_00007590 27caa445b7478752d96adb27875719d1 134 SUPERFAMILY SSF53098 22 119 3.03E-7 T 01-11-2018 IPR012337 Ribonuclease H-like superfamily AFULGI_00024710 be9bb572961b233fd19b54ad8f888158 416 PRINTS PR00415 Aconitase family signature 185 198 4.5E-19 T 01-11-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 AFULGI_00024710 be9bb572961b233fd19b54ad8f888158 416 PRINTS PR00415 Aconitase family signature 109 122 4.5E-19 T 01-11-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 AFULGI_00024710 be9bb572961b233fd19b54ad8f888158 416 PRINTS PR00415 Aconitase family signature 348 361 4.5E-19 T 01-11-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 AFULGI_00024710 be9bb572961b233fd19b54ad8f888158 416 PRINTS PR00415 Aconitase family signature 123 138 4.5E-19 T 01-11-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 AFULGI_00024710 be9bb572961b233fd19b54ad8f888158 416 PRINTS PR00415 Aconitase family signature 199 212 4.5E-19 T 01-11-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 AFULGI_00024710 be9bb572961b233fd19b54ad8f888158 416 PRINTS PR00415 Aconitase family signature 89 97 4.5E-19 T 01-11-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 AFULGI_00024710 be9bb572961b233fd19b54ad8f888158 416 ProSitePatterns PS00450 Aconitase family signature 1. 288 304 - T 01-11-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 AFULGI_00024710 be9bb572961b233fd19b54ad8f888158 416 Hamap MF_01027 3-isopropylmalate dehydratase large subunit [leuC]. 3 415 49.686 T 01-11-2018 IPR011826 Homoaconitase/3-isopropylmalate dehydratase, large subunit, prokaryotic GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 AFULGI_00024710 be9bb572961b233fd19b54ad8f888158 416 TIGRFAM TIGR01343 hacA_fam: homoaconitate hydratase family protein 4 413 1.3E-203 T 01-11-2018 IPR006251 Homoaconitase/3-isopropylmalate dehydratase, large subunit GO:0008652|GO:0016836|GO:0051539 KEGG: 00290+4.2.1.33 AFULGI_00024710 be9bb572961b233fd19b54ad8f888158 416 Gene3D G3DSA:3.30.499.20 4 266 1.2E-92 T 01-11-2018 AFULGI_00024710 be9bb572961b233fd19b54ad8f888158 416 Gene3D G3DSA:3.30.499.10 269 415 6.2E-62 T 01-11-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 AFULGI_00024710 be9bb572961b233fd19b54ad8f888158 416 Pfam PF00330 Aconitase family (aconitate hydratase) 7 407 4.6E-103 T 01-11-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 AFULGI_00024710 be9bb572961b233fd19b54ad8f888158 416 TIGRFAM TIGR02086 IPMI_arch: 3-isopropylmalate dehydratase, large subunit 3 414 3.4E-177 T 01-11-2018 IPR011826 Homoaconitase/3-isopropylmalate dehydratase, large subunit, prokaryotic GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 AFULGI_00024710 be9bb572961b233fd19b54ad8f888158 416 SUPERFAMILY SSF53732 1 415 3.4E-145 T 01-11-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 AFULGI_00024710 be9bb572961b233fd19b54ad8f888158 416 ProSitePatterns PS01244 Aconitase family signature 2. 348 361 - T 01-11-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 AFULGI_00024130 94dd24ac6ec83900eb812505a8032a0d 129 SUPERFAMILY SSF46785 19 113 3.14E-11 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00024130 94dd24ac6ec83900eb812505a8032a0d 129 Gene3D G3DSA:1.10.10.10 2 119 2.2E-32 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00024130 94dd24ac6ec83900eb812505a8032a0d 129 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 17 89 1.4E-15 T 01-11-2018 IPR002831 Transcription regulator TrmB, N-terminal AFULGI_00005240 de256ee7b6855b03f581a9f9fdb3c69a 187 Gene3D G3DSA:3.40.50.1820 9 186 5.6E-29 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold AFULGI_00005240 de256ee7b6855b03f581a9f9fdb3c69a 187 SUPERFAMILY SSF53474 20 184 2.61E-26 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold AFULGI_00005240 de256ee7b6855b03f581a9f9fdb3c69a 187 Pfam PF01738 Dienelactone hydrolase family 70 160 7.4E-7 T 01-11-2018 IPR002925 Dienelactone hydrolase GO:0016787 AFULGI_00010810 8049a07eede1651cc46104ee00a8c88c 327 Pfam PF02653 Branched-chain amino acid transport system / permease component 34 301 4.4E-29 T 01-11-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 AFULGI_00004290 ecf5b91c3658452c355b8a037e91c2ce 77 SUPERFAMILY SSF46785 5 71 5.17E-17 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00004290 ecf5b91c3658452c355b8a037e91c2ce 77 Gene3D G3DSA:1.10.10.10 5 76 9.4E-10 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00004290 ecf5b91c3658452c355b8a037e91c2ce 77 Pfam PF08679 Dissimilatory sulfite reductase D (DsrD) 9 64 7.4E-10 T 01-11-2018 IPR014793 Dissimilatory sulphite reductase D AFULGI_00021250 ecf5b91c3658452c355b8a037e91c2ce 77 SUPERFAMILY SSF46785 5 71 5.17E-17 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00021250 ecf5b91c3658452c355b8a037e91c2ce 77 Gene3D G3DSA:1.10.10.10 5 76 9.4E-10 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00021250 ecf5b91c3658452c355b8a037e91c2ce 77 Pfam PF08679 Dissimilatory sulfite reductase D (DsrD) 9 64 7.4E-10 T 01-11-2018 IPR014793 Dissimilatory sulphite reductase D AFULGI_00014940 ba1abede127ecd7d9a91f8e48154288e 97 Gene3D G3DSA:1.10.10.10 3 97 8.3E-32 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00014940 ba1abede127ecd7d9a91f8e48154288e 97 SUPERFAMILY SSF46785 14 95 6.17E-11 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00023120 22114634b256f9e4143ce0cd987bab62 221 TIGRFAM TIGR00473 pssA: CDP-diacylglycerol-serine O-phosphatidyltransferase 14 160 9.9E-54 T 01-11-2018 IPR004533 CDP-diacylglycerol--serine O-phosphatidyltransferase KEGG: 00260+2.7.8.8|KEGG: 00564+2.7.8.8|MetaCyc: PWY-5669 AFULGI_00023120 22114634b256f9e4143ce0cd987bab62 221 Pfam PF01066 CDP-alcohol phosphatidyltransferase 9 72 1.5E-10 T 01-11-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 AFULGI_00007520 0d30cc9236d9bda0374ec392148d5c80 504 Pfam PF13193 AMP-binding enzyme C-terminal domain 412 491 7.0E-14 T 01-11-2018 IPR025110 AMP-binding enzyme, C-terminal domain AFULGI_00007520 0d30cc9236d9bda0374ec392148d5c80 504 ProSitePatterns PS00455 Putative AMP-binding domain signature. 154 165 - T 01-11-2018 IPR020845 AMP-binding, conserved site AFULGI_00007520 0d30cc9236d9bda0374ec392148d5c80 504 Gene3D G3DSA:3.30.300.310 398 503 4.5E-25 T 01-11-2018 AFULGI_00007520 0d30cc9236d9bda0374ec392148d5c80 504 Gene3D G3DSA:3.40.50.12780 6 397 6.4E-86 T 01-11-2018 AFULGI_00007520 0d30cc9236d9bda0374ec392148d5c80 504 SUPERFAMILY SSF56801 5 503 1.31E-114 T 01-11-2018 AFULGI_00007520 0d30cc9236d9bda0374ec392148d5c80 504 Pfam PF00501 AMP-binding enzyme 18 402 1.4E-76 T 01-11-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFULGI_00020580 d4572bf30796dc2dee9131fdce9cdfd4 661 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 294 308 - T 01-11-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 AFULGI_00020580 d4572bf30796dc2dee9131fdce9cdfd4 661 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 578 617 1.0E-17 T 01-11-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 AFULGI_00020580 d4572bf30796dc2dee9131fdce9cdfd4 661 Pfam PF01751 Toprim domain 4 135 3.9E-16 T 01-11-2018 IPR006171 TOPRIM domain AFULGI_00020580 d4572bf30796dc2dee9131fdce9cdfd4 661 Gene3D G3DSA:1.10.290.10 267 389 4.8E-115 T 01-11-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 AFULGI_00020580 d4572bf30796dc2dee9131fdce9cdfd4 661 Pfam PF01131 DNA topoisomerase 152 545 1.8E-123 T 01-11-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 AFULGI_00020580 d4572bf30796dc2dee9131fdce9cdfd4 661 SMART SM00493 2 125 7.1E-32 T 01-11-2018 IPR006171 TOPRIM domain AFULGI_00020580 d4572bf30796dc2dee9131fdce9cdfd4 661 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 190 208 1.4E-26 T 01-11-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 AFULGI_00020580 d4572bf30796dc2dee9131fdce9cdfd4 661 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 299 308 1.4E-26 T 01-11-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 AFULGI_00020580 d4572bf30796dc2dee9131fdce9cdfd4 661 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 375 391 1.4E-26 T 01-11-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 AFULGI_00020580 d4572bf30796dc2dee9131fdce9cdfd4 661 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 99 112 1.4E-26 T 01-11-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 AFULGI_00020580 d4572bf30796dc2dee9131fdce9cdfd4 661 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 473 487 1.4E-26 T 01-11-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 AFULGI_00020580 d4572bf30796dc2dee9131fdce9cdfd4 661 SUPERFAMILY SSF56712 1 591 9.55E-153 T 01-11-2018 IPR023405 DNA topoisomerase, type IA, core domain AFULGI_00020580 d4572bf30796dc2dee9131fdce9cdfd4 661 Gene3D G3DSA:3.40.50.140 1 150 2.9E-36 T 01-11-2018 AFULGI_00020580 d4572bf30796dc2dee9131fdce9cdfd4 661 SUPERFAMILY SSF57783 580 617 8.16E-8 T 01-11-2018 AFULGI_00020580 d4572bf30796dc2dee9131fdce9cdfd4 661 Gene3D G3DSA:2.70.20.10 214 457 4.8E-115 T 01-11-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 AFULGI_00020580 d4572bf30796dc2dee9131fdce9cdfd4 661 Hamap MF_00952 DNA topoisomerase 1 [topA]. 2 649 49.393 T 01-11-2018 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 AFULGI_00020580 d4572bf30796dc2dee9131fdce9cdfd4 661 Gene3D G3DSA:1.10.460.10 159 556 4.8E-115 T 01-11-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 AFULGI_00020580 d4572bf30796dc2dee9131fdce9cdfd4 661 SMART SM00437 259 508 4.9E-98 T 01-11-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 AFULGI_00020580 d4572bf30796dc2dee9131fdce9cdfd4 661 SMART SM00436 128 220 6.9E-44 T 01-11-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 AFULGI_00019530 bb52f1fa1e8412dd3f29b7864bb6819d 271 Hamap MF_00996 1,4-dihydroxy-6-naphtoate synthase [mqnD]. 2 262 43.191 T 01-11-2018 IPR030869 1,4-dihydroxy-6-naphtoate synthase GO:0009234|GO:0016829 AFULGI_00019530 bb52f1fa1e8412dd3f29b7864bb6819d 271 SUPERFAMILY SSF53850 3 261 1.58E-93 T 01-11-2018 AFULGI_00019530 bb52f1fa1e8412dd3f29b7864bb6819d 271 Gene3D G3DSA:3.40.190.10 6 257 1.0E-100 T 01-11-2018 AFULGI_00019530 bb52f1fa1e8412dd3f29b7864bb6819d 271 Gene3D G3DSA:3.40.190.10 79 170 1.0E-100 T 01-11-2018 AFULGI_00019530 bb52f1fa1e8412dd3f29b7864bb6819d 271 Pfam PF02621 Menaquinone biosynthesis 3 256 5.7E-87 T 01-11-2018 IPR003773 Menaquinone biosynthesis enzyme AFULGI_00001120 84f5d2f81a2e7ad961d98240b0217325 257 Gene3D G3DSA:3.60.110.10 1 257 5.2E-79 T 01-11-2018 IPR036526 Carbon-nitrogen hydrolase superfamily AFULGI_00001120 84f5d2f81a2e7ad961d98240b0217325 257 SUPERFAMILY SSF56317 4 253 1.15E-72 T 01-11-2018 IPR036526 Carbon-nitrogen hydrolase superfamily AFULGI_00001120 84f5d2f81a2e7ad961d98240b0217325 257 Pfam PF00795 Carbon-nitrogen hydrolase 8 244 4.4E-62 T 01-11-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 AFULGI_00011000 56426080836cea1a8d8d0add1d7cf242 285 Pfam PF00005 ABC transporter 20 148 1.6E-28 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFULGI_00011000 56426080836cea1a8d8d0add1d7cf242 285 SMART SM00382 28 195 2.1E-14 T 01-11-2018 IPR003593 AAA+ ATPase domain AFULGI_00011000 56426080836cea1a8d8d0add1d7cf242 285 SUPERFAMILY SSF52540 3 207 6.82E-61 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00011000 56426080836cea1a8d8d0add1d7cf242 285 ProSitePatterns PS00211 ABC transporters family signature. 120 134 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFULGI_00011000 56426080836cea1a8d8d0add1d7cf242 285 Pfam PF13732 Domain of unknown function (DUF4162) 200 281 8.9E-7 T 01-11-2018 IPR025302 Domain of unknown function DUF4162 AFULGI_00011000 56426080836cea1a8d8d0add1d7cf242 285 Gene3D G3DSA:3.40.50.300 1 216 2.3E-62 T 01-11-2018 AFULGI_00011910 67b1e26555b23db80f45614f751d9cc8 62 SUPERFAMILY SSF141694 1 57 3.14E-16 T 01-11-2018 AFULGI_00011910 67b1e26555b23db80f45614f751d9cc8 62 Pfam PF01954 Protein of unknown function DUF104 1 59 2.1E-24 T 01-11-2018 IPR008203 Uncharacterised protein family UPF0165 AFULGI_00011910 67b1e26555b23db80f45614f751d9cc8 62 Gene3D G3DSA:4.10.1150.10 1 61 3.0E-19 T 01-11-2018 IPR024069 AF2212-like domain superfamily AFULGI_00017920 23e28a1143d2c87a68b89cc4336adc4f 486 TIGRFAM TIGR00366 TIGR00366: TIGR00366 family protein 11 472 3.5E-218 T 01-11-2018 IPR006161 Conserved hypothetical protein CHP00336 AFULGI_00017920 23e28a1143d2c87a68b89cc4336adc4f 486 Pfam PF02667 Short chain fatty acid transporter 9 484 1.9E-222 T 01-11-2018 IPR006160 Short chain fatty acid transporter AtoE AFULGI_00003670 08357a1380d549172843f4a9b408dbba 681 Gene3D G3DSA:3.40.50.12780 62 541 5.9E-100 T 01-11-2018 AFULGI_00003670 08357a1380d549172843f4a9b408dbba 681 Gene3D G3DSA:3.30.300.30 543 675 3.6E-28 T 01-11-2018 AFULGI_00003670 08357a1380d549172843f4a9b408dbba 681 Pfam PF13193 AMP-binding enzyme C-terminal domain 556 635 7.6E-25 T 01-11-2018 IPR025110 AMP-binding enzyme, C-terminal domain AFULGI_00003670 08357a1380d549172843f4a9b408dbba 681 Pfam PF00501 AMP-binding enzyme 95 547 2.0E-94 T 01-11-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFULGI_00003670 08357a1380d549172843f4a9b408dbba 681 SUPERFAMILY SSF56801 37 662 4.19E-162 T 01-11-2018 AFULGI_00003670 08357a1380d549172843f4a9b408dbba 681 TIGRFAM TIGR02188 Ac_CoA_lig_AcsA: acetate--CoA ligase 26 667 4.9E-279 T 01-11-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 AFULGI_00003670 08357a1380d549172843f4a9b408dbba 681 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 31 88 2.4E-15 T 01-11-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 AFULGI_00003670 08357a1380d549172843f4a9b408dbba 681 ProSitePatterns PS00455 Putative AMP-binding domain signature. 280 291 - T 01-11-2018 IPR020845 AMP-binding, conserved site AFULGI_00021380 8d675813d15abe5980c9ab603e9922d7 345 Gene3D G3DSA:3.100.10.20 1 80 7.1E-26 T 01-11-2018 AFULGI_00021380 8d675813d15abe5980c9ab603e9922d7 345 Pfam PF01867 CRISPR associated protein Cas1 3 299 9.0E-85 T 01-11-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 AFULGI_00021380 8d675813d15abe5980c9ab603e9922d7 345 Hamap MF_01470 CRISPR-associated endonuclease Cas1 [cas1]. 1 330 27.504 T 01-11-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 AFULGI_00021380 8d675813d15abe5980c9ab603e9922d7 345 TIGRFAM TIGR00287 cas1: CRISPR-associated endonuclease Cas1 3 339 1.0E-108 T 01-11-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 AFULGI_00021380 8d675813d15abe5980c9ab603e9922d7 345 Gene3D G3DSA:1.20.120.920 81 345 4.2E-86 T 01-11-2018 AFULGI_00016660 95044a60925b163631ca859eb030ffeb 255 SUPERFAMILY SSF55729 106 241 1.89E-11 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase AFULGI_00016660 95044a60925b163631ca859eb030ffeb 255 Pfam PF00583 Acetyltransferase (GNAT) family 145 236 3.5E-6 T 01-11-2018 IPR000182 GNAT domain AFULGI_00016660 95044a60925b163631ca859eb030ffeb 255 Gene3D G3DSA:3.40.630.30 52 243 4.2E-11 T 01-11-2018 AFULGI_00012870 55460decdee99dd81c6dad709d362195 503 SUPERFAMILY SSF52540 2 415 1.94E-15 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00012870 55460decdee99dd81c6dad709d362195 503 Pfam PF13175 AAA ATPase domain 2 404 1.0E-27 T 01-11-2018 AFULGI_00001950 7641655374a907687e0403ca9627c510 481 TIGRFAM TIGR03701 mena_SCO4490: menaquinone biosynthesis decarboxylase, SCO4490 family 8 437 3.0E-198 T 01-11-2018 IPR022390 4-hydroxybenzoate decarboxylase subunit C GO:0016831 AFULGI_00001950 7641655374a907687e0403ca9627c510 481 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 6 445 3.9E-190 T 01-11-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 AFULGI_00001950 7641655374a907687e0403ca9627c510 481 SUPERFAMILY SSF143968 314 476 1.03E-63 T 01-11-2018 AFULGI_00001950 7641655374a907687e0403ca9627c510 481 SUPERFAMILY SSF50475 3 313 2.86E-116 T 01-11-2018 AFULGI_00001950 7641655374a907687e0403ca9627c510 481 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 11 418 7.2E-171 T 01-11-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 AFULGI_00001950 7641655374a907687e0403ca9627c510 481 Gene3D G3DSA:3.40.1670.10 328 444 7.0E-44 T 01-11-2018 AFULGI_00007100 33a207e08417b9a1e58aea596ebb32ad 160 Pfam PF01988 VIT family 44 151 2.0E-11 T 01-11-2018 IPR008217 Ccc1 family AFULGI_00004310 ff791711561b16c32e5d5fc57ffd03c9 63 SUPERFAMILY SSF54862 4 59 1.44E-16 T 01-11-2018 AFULGI_00004310 ff791711561b16c32e5d5fc57ffd03c9 63 PRINTS PR00352 3Fe-4S ferredoxin signature 45 57 8.9E-5 T 01-11-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 AFULGI_00004310 ff791711561b16c32e5d5fc57ffd03c9 63 PRINTS PR00352 3Fe-4S ferredoxin signature 17 27 8.9E-5 T 01-11-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 AFULGI_00004310 ff791711561b16c32e5d5fc57ffd03c9 63 PRINTS PR00352 3Fe-4S ferredoxin signature 6 17 8.9E-5 T 01-11-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 AFULGI_00004310 ff791711561b16c32e5d5fc57ffd03c9 63 Pfam PF13237 4Fe-4S dicluster domain 4 53 3.2E-9 T 01-11-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFULGI_00004310 ff791711561b16c32e5d5fc57ffd03c9 63 Gene3D G3DSA:3.30.70.20 3 60 2.4E-19 T 01-11-2018 AFULGI_00012060 87fb929a926b6b0cc2bd5218e2cb6398 113 Pfam PF04434 SWIM zinc finger 49 89 1.7E-8 T 01-11-2018 IPR007527 Zinc finger, SWIM-type GO:0008270 AFULGI_00000080 32206b5d61d8117f9268b15a1e8c0cbb 597 Gene3D G3DSA:3.10.20.30 1 98 2.7E-22 T 01-11-2018 IPR012675 Beta-grasp domain superfamily AFULGI_00000080 32206b5d61d8117f9268b15a1e8c0cbb 597 Pfam PF14574 Domain of unknown function (DUF4445) 190 594 8.3E-142 T 01-11-2018 IPR027980 Protein of unknown function DUF4445 AFULGI_00000080 32206b5d61d8117f9268b15a1e8c0cbb 597 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 10 84 9.5E-13 T 01-11-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 AFULGI_00000080 32206b5d61d8117f9268b15a1e8c0cbb 597 Gene3D G3DSA:3.30.420.480 188 362 2.6E-55 T 01-11-2018 AFULGI_00000080 32206b5d61d8117f9268b15a1e8c0cbb 597 Gene3D G3DSA:2.40.50.570 110 187 4.7E-11 T 01-11-2018 AFULGI_00000080 32206b5d61d8117f9268b15a1e8c0cbb 597 SUPERFAMILY SSF54292 2 92 1.66E-19 T 01-11-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 AFULGI_00000960 e7bcca505acebe8470de75c14f81977d 154 SUPERFAMILY SSF88723 1 114 9.25E-12 T 01-11-2018 IPR029060 PIN-like domain superfamily AFULGI_00000960 e7bcca505acebe8470de75c14f81977d 154 Pfam PF11848 Domain of unknown function (DUF3368) 110 154 7.7E-8 T 01-11-2018 IPR021799 Protein of unknown function DUF3368 AFULGI_00006670 92c4414100f8d51127d1940df7b3bffe 424 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 25 213 8.1E-13 T 01-11-2018 IPR005225 Small GTP-binding protein domain GO:0005525 AFULGI_00006670 92c4414100f8d51127d1940df7b3bffe 424 Pfam PF09173 Initiation factor eIF2 gamma, C terminal 339 423 7.3E-33 T 01-11-2018 IPR015256 Translation initiation factor 2, gamma subunit, C-terminal AFULGI_00006670 92c4414100f8d51127d1940df7b3bffe 424 Gene3D G3DSA:2.40.30.10 334 424 2.6E-31 T 01-11-2018 AFULGI_00006670 92c4414100f8d51127d1940df7b3bffe 424 Pfam PF03144 Elongation factor Tu domain 2 249 327 1.6E-9 T 01-11-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 AFULGI_00006670 92c4414100f8d51127d1940df7b3bffe 424 TIGRFAM TIGR03680 eif2g_arch: translation initiation factor 2, gamma subunit 23 424 1.3E-205 T 01-11-2018 IPR022424 Translation initiation factor 2, gamma subunit AFULGI_00006670 92c4414100f8d51127d1940df7b3bffe 424 Gene3D G3DSA:3.40.50.300 23 221 3.9E-60 T 01-11-2018 AFULGI_00006670 92c4414100f8d51127d1940df7b3bffe 424 Gene3D G3DSA:2.40.30.10 222 333 2.2E-40 T 01-11-2018 AFULGI_00006670 92c4414100f8d51127d1940df7b3bffe 424 SUPERFAMILY SSF50465 332 424 3.96E-33 T 01-11-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal AFULGI_00006670 92c4414100f8d51127d1940df7b3bffe 424 SUPERFAMILY SSF50447 221 331 7.28E-35 T 01-11-2018 IPR009000 Translation protein, beta-barrel domain superfamily AFULGI_00006670 92c4414100f8d51127d1940df7b3bffe 424 Hamap MF_00119 Translation initiation factor 2 subunit gamma [eif2g]. 18 424 64.35 T 01-11-2018 IPR022424 Translation initiation factor 2, gamma subunit AFULGI_00006670 92c4414100f8d51127d1940df7b3bffe 424 Pfam PF00009 Elongation factor Tu GTP binding domain 26 217 1.6E-28 T 01-11-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFULGI_00006670 92c4414100f8d51127d1940df7b3bffe 424 SUPERFAMILY SSF52540 7 229 7.66E-48 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00006670 92c4414100f8d51127d1940df7b3bffe 424 PRINTS PR00315 GTP-binding elongation factor signature 104 114 2.0E-13 T 01-11-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFULGI_00006670 92c4414100f8d51127d1940df7b3bffe 424 PRINTS PR00315 GTP-binding elongation factor signature 120 131 2.0E-13 T 01-11-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFULGI_00006670 92c4414100f8d51127d1940df7b3bffe 424 PRINTS PR00315 GTP-binding elongation factor signature 158 167 2.0E-13 T 01-11-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFULGI_00006670 92c4414100f8d51127d1940df7b3bffe 424 PRINTS PR00315 GTP-binding elongation factor signature 27 40 2.0E-13 T 01-11-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFULGI_00024570 2900ed318f2cc734076929252d156fb1 380 Gene3D G3DSA:3.30.470.20 1 225 6.7E-78 T 01-11-2018 AFULGI_00024570 2900ed318f2cc734076929252d156fb1 380 PIRSF PIRSF001554 1 380 7.5E-143 T 01-11-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 AFULGI_00024570 2900ed318f2cc734076929252d156fb1 380 SUPERFAMILY SSF52210 230 377 4.58E-47 T 01-11-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AFULGI_00024570 2900ed318f2cc734076929252d156fb1 380 Pfam PF08442 ATP-grasp domain 2 195 2.1E-71 T 01-11-2018 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 AFULGI_00024570 2900ed318f2cc734076929252d156fb1 380 Pfam PF00549 CoA-ligase 254 348 4.5E-17 T 01-11-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AFULGI_00024570 2900ed318f2cc734076929252d156fb1 380 SUPERFAMILY SSF56059 1 228 2.3E-67 T 01-11-2018 AFULGI_00024570 2900ed318f2cc734076929252d156fb1 380 Gene3D G3DSA:3.30.1490.20 21 96 6.7E-78 T 01-11-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 AFULGI_00024570 2900ed318f2cc734076929252d156fb1 380 Gene3D G3DSA:3.40.50.261 231 380 5.2E-49 T 01-11-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AFULGI_00024570 2900ed318f2cc734076929252d156fb1 380 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 1 377 3.3E-167 T 01-11-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 AFULGI_00024570 2900ed318f2cc734076929252d156fb1 380 Hamap MF_00558 Succinate--CoA ligase [ADP-forming] subunit beta [sucC]. 1 378 40.301 T 01-11-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 AFULGI_00024570 2900ed318f2cc734076929252d156fb1 380 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 248 273 - T 01-11-2018 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AFULGI_00019950 d87add911f3dd6770e150f407b9ea235 187 Gene3D G3DSA:1.20.120.1760 7 186 5.1E-49 T 01-11-2018 AFULGI_00019950 d87add911f3dd6770e150f407b9ea235 187 Pfam PF01066 CDP-alcohol phosphatidyltransferase 27 89 8.6E-15 T 01-11-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 AFULGI_00019950 d87add911f3dd6770e150f407b9ea235 187 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 67 89 - T 01-11-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 AFULGI_00002080 b6e2a7edddd2d2095c6f487f5ef39347 227 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 199 221 4.1E-6 T 01-11-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal AFULGI_00002080 b6e2a7edddd2d2095c6f487f5ef39347 227 SMART SM00382 26 220 1.0E-9 T 01-11-2018 IPR003593 AAA+ ATPase domain AFULGI_00002080 b6e2a7edddd2d2095c6f487f5ef39347 227 Pfam PF00005 ABC transporter 20 150 5.7E-29 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFULGI_00002080 b6e2a7edddd2d2095c6f487f5ef39347 227 SUPERFAMILY SSF52540 2 222 6.29E-59 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00002080 b6e2a7edddd2d2095c6f487f5ef39347 227 Gene3D G3DSA:3.40.50.300 1 224 1.1E-58 T 01-11-2018 AFULGI_00002080 b6e2a7edddd2d2095c6f487f5ef39347 227 ProSitePatterns PS00211 ABC transporters family signature. 123 137 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFULGI_00000290 94c3be49b8f77f4d9fc45efe6155518e 339 PIRSF PIRSF018978 1 339 2.5E-150 T 01-11-2018 IPR016742 tRNA methyltransferase, archaea GO:0008175|GO:0030488 AFULGI_00000290 94c3be49b8f77f4d9fc45efe6155518e 339 Gene3D G3DSA:3.40.1280.30 87 255 2.9E-5 T 01-11-2018 IPR038459 tRNA methyltransferase TRM10-type domain superfamily AFULGI_00021570 d35f9a4f5528198914e1dd23de03505e 117 Pfam PF00072 Response regulator receiver domain 4 110 1.2E-27 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFULGI_00021570 d35f9a4f5528198914e1dd23de03505e 117 SUPERFAMILY SSF52172 1 115 1.25E-35 T 01-11-2018 IPR011006 CheY-like superfamily AFULGI_00021570 d35f9a4f5528198914e1dd23de03505e 117 Gene3D G3DSA:3.40.50.2300 1 117 7.9E-38 T 01-11-2018 AFULGI_00021570 d35f9a4f5528198914e1dd23de03505e 117 SMART SM00448 2 110 1.9E-32 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFULGI_00022000 67df3fd76cb28e3fcb330571dc81f78d 765 Pfam PF00586 AIR synthase related protein, N-terminal domain 99 221 4.1E-20 T 01-11-2018 IPR016188 PurM-like, N-terminal domain AFULGI_00022000 67df3fd76cb28e3fcb330571dc81f78d 765 Pfam PF00586 AIR synthase related protein, N-terminal domain 478 595 8.7E-14 T 01-11-2018 IPR016188 PurM-like, N-terminal domain AFULGI_00022000 67df3fd76cb28e3fcb330571dc81f78d 765 Pfam PF02769 AIR synthase related protein, C-terminal domain 610 737 1.9E-15 T 01-11-2018 IPR010918 PurM-like, C-terminal domain AFULGI_00022000 67df3fd76cb28e3fcb330571dc81f78d 765 Pfam PF02769 AIR synthase related protein, C-terminal domain 234 388 2.1E-36 T 01-11-2018 IPR010918 PurM-like, C-terminal domain AFULGI_00022000 67df3fd76cb28e3fcb330571dc81f78d 765 SUPERFAMILY SSF55326 428 603 3.27E-49 T 01-11-2018 IPR036921 PurM-like, N-terminal domain superfamily AFULGI_00022000 67df3fd76cb28e3fcb330571dc81f78d 765 Gene3D G3DSA:3.30.1330.10 415 599 1.9E-50 T 01-11-2018 IPR036921 PurM-like, N-terminal domain superfamily AFULGI_00022000 67df3fd76cb28e3fcb330571dc81f78d 765 Gene3D G3DSA:3.90.650.10 220 404 6.0E-57 T 01-11-2018 IPR036676 PurM-like, C-terminal domain superfamily AFULGI_00022000 67df3fd76cb28e3fcb330571dc81f78d 765 SUPERFAMILY SSF56042 233 454 1.5E-53 T 01-11-2018 IPR036676 PurM-like, C-terminal domain superfamily AFULGI_00022000 67df3fd76cb28e3fcb330571dc81f78d 765 SUPERFAMILY SSF56042 610 761 1.17E-26 T 01-11-2018 IPR036676 PurM-like, C-terminal domain superfamily AFULGI_00022000 67df3fd76cb28e3fcb330571dc81f78d 765 Gene3D G3DSA:1.10.8.750 7 65 8.5E-11 T 01-11-2018 AFULGI_00022000 67df3fd76cb28e3fcb330571dc81f78d 765 Gene3D G3DSA:3.90.650.10 605 765 8.7E-28 T 01-11-2018 IPR036676 PurM-like, C-terminal domain superfamily AFULGI_00022000 67df3fd76cb28e3fcb330571dc81f78d 765 Hamap MF_00420 Phosphoribosylformylglycinamidine synthase subunit PurL [purL]. 1 765 234.947 T 01-11-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 AFULGI_00022000 67df3fd76cb28e3fcb330571dc81f78d 765 PIRSF PIRSF001587 18 765 1.5E-221 T 01-11-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 AFULGI_00022000 67df3fd76cb28e3fcb330571dc81f78d 765 Gene3D G3DSA:3.30.1330.10 66 219 8.2E-52 T 01-11-2018 IPR036921 PurM-like, N-terminal domain superfamily AFULGI_00022000 67df3fd76cb28e3fcb330571dc81f78d 765 SUPERFAMILY SSF55326 39 227 2.3E-48 T 01-11-2018 IPR036921 PurM-like, N-terminal domain superfamily AFULGI_00022000 67df3fd76cb28e3fcb330571dc81f78d 765 TIGRFAM TIGR01736 FGAM_synth_II: phosphoribosylformylglycinamidine synthase II 35 764 5.6E-294 T 01-11-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 AFULGI_00020550 444ac52ed4b3ea987f958dacd856c7c1 310 TIGRFAM TIGR00322 diphth2_R: diphthamide biosynthesis enzyme Dph1/Dph2 domain 12 297 3.3E-78 T 01-11-2018 IPR016435 Diphthamide synthesis DPH1/DPH2 MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 AFULGI_00020550 444ac52ed4b3ea987f958dacd856c7c1 310 Gene3D G3DSA:3.40.50.11860 197 297 4.2E-28 T 01-11-2018 AFULGI_00020550 444ac52ed4b3ea987f958dacd856c7c1 310 PIRSF PIRSF004967 5 310 2.5E-72 T 01-11-2018 IPR035435 Diphthamide synthesis DHP1/DPH2, eukaryotes and archaea GO:0017183 MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 AFULGI_00020550 444ac52ed4b3ea987f958dacd856c7c1 310 TIGRFAM TIGR03682 arCOG04112: diphthamide biosynthesis enzyme Dph2 13 308 2.2E-108 T 01-11-2018 IPR022428 Diphthamide synthesis Dph2, archaea GO:0017183 MetaCyc: PWY-6482|MetaCyc: PWY-7546 AFULGI_00020550 444ac52ed4b3ea987f958dacd856c7c1 310 Pfam PF01866 Putative diphthamide synthesis protein 21 301 3.2E-69 T 01-11-2018 IPR016435 Diphthamide synthesis DPH1/DPH2 MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 AFULGI_00020550 444ac52ed4b3ea987f958dacd856c7c1 310 Gene3D G3DSA:3.40.50.11850 91 193 3.5E-31 T 01-11-2018 AFULGI_00020550 444ac52ed4b3ea987f958dacd856c7c1 310 Gene3D G3DSA:3.40.50.11840 7 90 2.4E-18 T 01-11-2018 AFULGI_00003770 dcd2cd7565feb38e2cba7912cd12d5f6 452 Gene3D G3DSA:3.20.20.20 127 437 1.9E-121 T 01-11-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFULGI_00003770 dcd2cd7565feb38e2cba7912cd12d5f6 452 Hamap MF_01135 Acetyl-CoA decarbonylase/synthase complex subunit delta [cdhD]. 24 450 54.969 T 01-11-2018 IPR004486 CO dehydrogenase/acetyl-CoA synthase delta subunit GO:0006730 AFULGI_00003770 dcd2cd7565feb38e2cba7912cd12d5f6 452 Pfam PF03599 CO dehydrogenase/acetyl-CoA synthase delta subunit 128 380 1.7E-85 T 01-11-2018 IPR016041 CO dehydrogenase/acetyl-CoA synthase delta subunit, TIM barrel AFULGI_00003770 dcd2cd7565feb38e2cba7912cd12d5f6 452 TIGRFAM TIGR00381 cdhD: CO dehydrogenase/acetyl-CoA synthase, delta subunit 51 448 1.1E-212 T 01-11-2018 IPR004486 CO dehydrogenase/acetyl-CoA synthase delta subunit GO:0006730 AFULGI_00003770 dcd2cd7565feb38e2cba7912cd12d5f6 452 SUPERFAMILY SSF51717 182 371 4.19E-20 T 01-11-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFULGI_00003020 d02ffe9b796e969e2e4a83696f96f5cf 256 SUPERFAMILY SSF53335 104 169 2.62E-13 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFULGI_00003020 d02ffe9b796e969e2e4a83696f96f5cf 256 Gene3D G3DSA:3.40.50.150 92 201 2.8E-14 T 01-11-2018 AFULGI_00003020 d02ffe9b796e969e2e4a83696f96f5cf 256 Pfam PF08241 Methyltransferase domain 103 152 9.0E-10 T 01-11-2018 IPR013216 Methyltransferase type 11 GO:0008168 AFULGI_00002240 a3bcf028588b53512d258b9a3b7d2d27 194 Gene3D G3DSA:3.40.50.2020 4 179 7.6E-47 T 01-11-2018 AFULGI_00002240 a3bcf028588b53512d258b9a3b7d2d27 194 SUPERFAMILY SSF53271 2 158 3.15E-43 T 01-11-2018 IPR029057 Phosphoribosyltransferase-like AFULGI_00002240 a3bcf028588b53512d258b9a3b7d2d27 194 Pfam PF00156 Phosphoribosyl transferase domain 10 150 6.8E-25 T 01-11-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 AFULGI_00004100 5ba0b6517d943ecd3f3cdf385e0c36c5 72 Gene3D G3DSA:2.20.28.30 1 42 2.1E-5 T 01-11-2018 AFULGI_00002550 9b96509e35ffeff73a42c4001915090d 420 Pfam PF01066 CDP-alcohol phosphatidyltransferase 249 310 3.3E-8 T 01-11-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 AFULGI_00002550 9b96509e35ffeff73a42c4001915090d 420 Pfam PF12804 MobA-like NTP transferase domain 3 108 2.7E-17 T 01-11-2018 IPR025877 MobA-like NTP transferase AFULGI_00002550 9b96509e35ffeff73a42c4001915090d 420 Gene3D G3DSA:1.20.120.1760 223 417 6.1E-77 T 01-11-2018 AFULGI_00002550 9b96509e35ffeff73a42c4001915090d 420 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 288 310 - T 01-11-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 AFULGI_00002550 9b96509e35ffeff73a42c4001915090d 420 Gene3D G3DSA:3.90.550.10 1 214 6.9E-68 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFULGI_00002550 9b96509e35ffeff73a42c4001915090d 420 SUPERFAMILY SSF53448 1 216 2.93E-33 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFULGI_00023860 fec3007163cc83c82443f5c69378c9bf 183 Pfam PF00571 CBS domain 130 181 6.6E-9 T 01-11-2018 IPR000644 CBS domain AFULGI_00023860 fec3007163cc83c82443f5c69378c9bf 183 Pfam PF00571 CBS domain 68 119 9.5E-13 T 01-11-2018 IPR000644 CBS domain AFULGI_00023860 fec3007163cc83c82443f5c69378c9bf 183 Gene3D G3DSA:1.10.260.40 4 64 8.7E-14 T 01-11-2018 AFULGI_00023860 fec3007163cc83c82443f5c69378c9bf 183 SUPERFAMILY SSF54631 65 182 4.42E-26 T 01-11-2018 AFULGI_00023860 fec3007163cc83c82443f5c69378c9bf 183 SMART SM00116 72 119 8.6E-10 T 01-11-2018 IPR000644 CBS domain AFULGI_00023860 fec3007163cc83c82443f5c69378c9bf 183 SMART SM00116 137 182 1.0E-5 T 01-11-2018 IPR000644 CBS domain AFULGI_00023860 fec3007163cc83c82443f5c69378c9bf 183 PIRSF PIRSF037253 1 183 2.0E-81 T 01-11-2018 IPR017158 Transcription regulator, CBS domain-containing, predicted AFULGI_00023860 fec3007163cc83c82443f5c69378c9bf 183 SMART SM00530 7 58 1.4E-12 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFULGI_00023860 fec3007163cc83c82443f5c69378c9bf 183 Gene3D G3DSA:3.10.580.10 65 183 1.5E-29 T 01-11-2018 AFULGI_00023860 fec3007163cc83c82443f5c69378c9bf 183 SUPERFAMILY SSF47413 6 56 1.07E-12 T 01-11-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFULGI_00023860 fec3007163cc83c82443f5c69378c9bf 183 Pfam PF01381 Helix-turn-helix 8 55 4.0E-14 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFULGI_00002380 6021f73d3816ce353773ffcf5c2f3465 60 Gene3D G3DSA:2.20.25.10 8 60 2.4E-14 T 01-11-2018 AFULGI_00002380 6021f73d3816ce353773ffcf5c2f3465 60 Pfam PF03966 Trm112p-like protein 2 49 3.8E-12 T 01-11-2018 IPR005651 Trm112-like AFULGI_00002380 6021f73d3816ce353773ffcf5c2f3465 60 SUPERFAMILY SSF158997 3 59 1.83E-14 T 01-11-2018 AFULGI_00003120 eaca9807b56803735760d927b8519da9 74 Gene3D G3DSA:4.10.1150.10 1 68 2.2E-17 T 01-11-2018 IPR024069 AF2212-like domain superfamily AFULGI_00003120 eaca9807b56803735760d927b8519da9 74 SUPERFAMILY SSF141694 1 41 7.85E-15 T 01-11-2018 AFULGI_00003120 eaca9807b56803735760d927b8519da9 74 Pfam PF01954 Protein of unknown function DUF104 1 64 4.7E-19 T 01-11-2018 IPR008203 Uncharacterised protein family UPF0165 AFULGI_00017800 2ad34dae2011ec79aa4f092a810a89af 145 SUPERFAMILY SSF52402 1 144 4.35E-11 T 01-11-2018 AFULGI_00017800 2ad34dae2011ec79aa4f092a810a89af 145 Pfam PF00582 Universal stress protein family 2 144 2.1E-19 T 01-11-2018 IPR006016 UspA AFULGI_00017800 2ad34dae2011ec79aa4f092a810a89af 145 Gene3D G3DSA:3.40.50.620 1 144 2.3E-10 T 01-11-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFULGI_00004070 a74486d7eaa47755b689b9d617f90517 231 Gene3D G3DSA:3.20.20.390 1 231 1.0E-95 T 01-11-2018 IPR038597 GGGP/HepGP synthase superfamily AFULGI_00004070 a74486d7eaa47755b689b9d617f90517 231 TIGRFAM TIGR04146 GGGPS_Afulg: phosphoglycerol geranylgeranyltransferase 3 230 2.9E-108 T 01-11-2018 IPR026438 Geranylgeranylglyceryl phosphate synthase, archaea GO:0002094|GO:0046474 KEGG: 00564+2.5.1.41|MetaCyc: PWY-6349 AFULGI_00004070 a74486d7eaa47755b689b9d617f90517 231 Pfam PF01884 PcrB family 1 229 3.6E-103 T 01-11-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 AFULGI_00004070 a74486d7eaa47755b689b9d617f90517 231 TIGRFAM TIGR01768 GGGP-family: geranylgeranylglyceryl phosphate synthase family protein 7 230 7.7E-95 T 01-11-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 AFULGI_00004070 a74486d7eaa47755b689b9d617f90517 231 Hamap MF_00112 Geranylgeranylglyceryl phosphate synthase [pcrB]. 2 229 27.298 T 01-11-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 AFULGI_00004070 a74486d7eaa47755b689b9d617f90517 231 SUPERFAMILY SSF51395 1 224 2.93E-53 T 01-11-2018 AFULGI_00008140 fd083acd0dbf9a047e65fbf264501fa8 219 Gene3D G3DSA:3.40.1280.10 1 219 2.2E-93 T 01-11-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal AFULGI_00008140 fd083acd0dbf9a047e65fbf264501fa8 219 Hamap MF_00554 Ribosomal RNA small subunit methyltransferase Nep1 [nep1]. 3 212 38.367 T 01-11-2018 IPR023503 Ribosome biogenesis methyltransferase NEP1, archaea GO:0008168 AFULGI_00008140 fd083acd0dbf9a047e65fbf264501fa8 219 Pfam PF03587 EMG1/NEP1 methyltransferase 6 211 4.7E-44 T 01-11-2018 IPR005304 Ribosomal biogenesis, methyltransferase, EMG1/NEP1 GO:0008168 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 AFULGI_00008140 fd083acd0dbf9a047e65fbf264501fa8 219 SUPERFAMILY SSF75217 5 211 2.49E-54 T 01-11-2018 IPR029028 Alpha/beta knot methyltransferases AFULGI_00024210 d74b13239a20e762b6fa5aa2f341dea4 175 Pfam PF00857 Isochorismatase family 3 170 6.6E-51 T 01-11-2018 IPR000868 Isochorismatase-like GO:0003824 AFULGI_00024210 d74b13239a20e762b6fa5aa2f341dea4 175 SUPERFAMILY SSF52499 3 174 2.22E-63 T 01-11-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 AFULGI_00024210 d74b13239a20e762b6fa5aa2f341dea4 175 Gene3D G3DSA:3.40.50.850 1 175 3.2E-64 T 01-11-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 AFULGI_00024990 dc7c112d5ee14cd98b6982a9f9086ef3 250 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 45 238 1.5E-70 T 01-11-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 AFULGI_00024990 dc7c112d5ee14cd98b6982a9f9086ef3 250 Gene3D G3DSA:3.90.850.10 23 242 3.0E-87 T 01-11-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 AFULGI_00024990 dc7c112d5ee14cd98b6982a9f9086ef3 250 SUPERFAMILY SSF56529 38 240 1.22E-81 T 01-11-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 AFULGI_00004900 3612a198078f7a0ce534b08027e942c2 632 SMART SM00849 190 386 2.2E-29 T 01-11-2018 IPR001279 Metallo-beta-lactamase AFULGI_00004900 3612a198078f7a0ce534b08027e942c2 632 Gene3D G3DSA:3.30.300.20 64 134 2.6E-60 T 01-11-2018 IPR015946 K homology domain-like, alpha/beta AFULGI_00004900 3612a198078f7a0ce534b08027e942c2 632 SUPERFAMILY SSF54814 86 132 5.62E-5 T 01-11-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 AFULGI_00004900 3612a198078f7a0ce534b08027e942c2 632 Pfam PF10996 Beta-Casp domain 418 542 3.9E-26 T 01-11-2018 IPR022712 Beta-Casp domain AFULGI_00004900 3612a198078f7a0ce534b08027e942c2 632 Gene3D G3DSA:3.60.15.10 183 612 7.9E-153 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFULGI_00004900 3612a198078f7a0ce534b08027e942c2 632 SMART SM01027 417 542 6.3E-57 T 01-11-2018 IPR022712 Beta-Casp domain AFULGI_00004900 3612a198078f7a0ce534b08027e942c2 632 Gene3D G3DSA:3.30.300.230 10 168 2.6E-60 T 01-11-2018 AFULGI_00004900 3612a198078f7a0ce534b08027e942c2 632 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 560 623 1.6E-15 T 01-11-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain AFULGI_00004900 3612a198078f7a0ce534b08027e942c2 632 SMART SM00322 94 164 1.1E-5 T 01-11-2018 IPR004087 K Homology domain GO:0003676 AFULGI_00004900 3612a198078f7a0ce534b08027e942c2 632 Pfam PF16661 Metallo-beta-lactamase superfamily domain 195 361 2.5E-12 T 01-11-2018 IPR001279 Metallo-beta-lactamase AFULGI_00004900 3612a198078f7a0ce534b08027e942c2 632 Pfam PF17214 KH domain 3 68 7.4E-25 T 01-11-2018 IPR033769 KH domain, archaeal AFULGI_00004900 3612a198078f7a0ce534b08027e942c2 632 SUPERFAMILY SSF56281 177 631 5.59E-138 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFULGI_00004900 3612a198078f7a0ce534b08027e942c2 632 TIGRFAM TIGR03675 arCOG00543: arCOG00543 universal archaeal KH-domain/beta-lactamase-domain protein 6 631 0.0 T 01-11-2018 IPR019975 KH-domain/beta-lactamase-domain protein, archaea AFULGI_00004900 3612a198078f7a0ce534b08027e942c2 632 Gene3D G3DSA:3.40.50.10890 385 572 7.9E-153 T 01-11-2018 AFULGI_00023800 e14e209d0e6fa98f4b4e76490321c7a6 311 Gene3D G3DSA:3.20.20.210 1 310 3.7E-31 T 01-11-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 AFULGI_00023800 e14e209d0e6fa98f4b4e76490321c7a6 311 SUPERFAMILY SSF51726 4 308 1.44E-21 T 01-11-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 AFULGI_00023140 bbedd19f472a7dbc074eb2e609d5dc49 248 PIRSF PIRSF025737 1 248 3.8E-108 T 01-11-2018 IPR014522 Archaeosortase A AFULGI_00023140 bbedd19f472a7dbc074eb2e609d5dc49 248 TIGRFAM TIGR04125 exosort_PGF_TRM: archaeosortase A 4 239 1.9E-65 T 01-11-2018 IPR014522 Archaeosortase A AFULGI_00023140 bbedd19f472a7dbc074eb2e609d5dc49 248 Pfam PF09721 Transmembrane exosortase (Exosortase_EpsH) 8 209 9.3E-12 T 01-11-2018 IPR019127 Exosortase AFULGI_00023140 bbedd19f472a7dbc074eb2e609d5dc49 248 TIGRFAM TIGR04178 exo_archaeo: exosortase/archaeosortase family protein 137 231 2.1E-20 T 01-11-2018 IPR026392 Exosortase/Archaeosortase domain AFULGI_00005620 be7b4323305c51e70c59b2b93b5302d6 88 Gene3D G3DSA:3.10.20.30 1 88 1.4E-20 T 01-11-2018 IPR012675 Beta-grasp domain superfamily AFULGI_00005620 be7b4323305c51e70c59b2b93b5302d6 88 SUPERFAMILY SSF54285 1 88 1.96E-18 T 01-11-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp AFULGI_00005620 be7b4323305c51e70c59b2b93b5302d6 88 Pfam PF02597 ThiS family 14 88 4.6E-14 T 01-11-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 AFULGI_00005620 be7b4323305c51e70c59b2b93b5302d6 88 TIGRFAM TIGR01687 moaD_arch: MoaD family protein 11 88 1.8E-15 T 01-11-2018 IPR010038 MoaD, archaeal-type AFULGI_00021080 c8e3d6a7db29ad3a4967243fd8657dc0 474 Gene3D G3DSA:3.40.1080.20 307 459 2.4E-49 T 01-11-2018 IPR038460 Acetyl-CoA hydrolase/transferase, C-terminal domain superfamily AFULGI_00021080 c8e3d6a7db29ad3a4967243fd8657dc0 474 Gene3D G3DSA:3.30.750.70 201 306 5.4E-37 T 01-11-2018 AFULGI_00021080 c8e3d6a7db29ad3a4967243fd8657dc0 474 SUPERFAMILY SSF100950 4 237 4.79E-23 T 01-11-2018 IPR037171 NagB/RpiA transferase-like AFULGI_00021080 c8e3d6a7db29ad3a4967243fd8657dc0 474 SUPERFAMILY SSF100950 202 469 1.19E-57 T 01-11-2018 IPR037171 NagB/RpiA transferase-like AFULGI_00021080 c8e3d6a7db29ad3a4967243fd8657dc0 474 Pfam PF13336 Acetyl-CoA hydrolase/transferase C-terminal domain 289 449 7.3E-56 T 01-11-2018 IPR026888 Acetyl-CoA hydrolase/transferase C-terminal domain AFULGI_00021080 c8e3d6a7db29ad3a4967243fd8657dc0 474 Gene3D G3DSA:3.40.1080.10 1 193 1.1E-40 T 01-11-2018 AFULGI_00021080 c8e3d6a7db29ad3a4967243fd8657dc0 474 Pfam PF02550 Acetyl-CoA hydrolase/transferase N-terminal domain 3 199 1.2E-81 T 01-11-2018 IPR003702 Acetyl-CoA hydrolase/transferase GO:0003824|GO:0006084 AFULGI_00017890 dcc67b6aa70e8d6d95d05d0914e02da3 106 Gene3D G3DSA:3.90.460.10 2 101 1.5E-18 T 01-11-2018 IPR036644 Ferredoxin thioredoxin reductase catalytic beta subunit superfamily GO:0016730|GO:0055114 AFULGI_00017890 dcc67b6aa70e8d6d95d05d0914e02da3 106 SUPERFAMILY SSF57662 4 105 2.22E-31 T 01-11-2018 IPR036644 Ferredoxin thioredoxin reductase catalytic beta subunit superfamily GO:0016730|GO:0055114 AFULGI_00017890 dcc67b6aa70e8d6d95d05d0914e02da3 106 Pfam PF02943 Ferredoxin thioredoxin reductase catalytic beta chain 7 93 8.2E-23 T 01-11-2018 IPR004209 Ferredoxin thioredoxin reductase catalytic beta subunit GO:0016730|GO:0055114 AFULGI_00020020 ba1af87983f9afe1cd07e316b94bf522 408 SUPERFAMILY SSF53649 2 403 6.35E-38 T 01-11-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 AFULGI_00020020 ba1af87983f9afe1cd07e316b94bf522 408 TIGRFAM TIGR00306 apgM: phosphoglycerate mutase (2,3-diphosphoglycerate-independent), archaeal form 4 398 4.7E-180 T 01-11-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFULGI_00020020 ba1af87983f9afe1cd07e316b94bf522 408 PIRSF PIRSF006392 1 404 1.8E-160 T 01-11-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFULGI_00020020 ba1af87983f9afe1cd07e316b94bf522 408 Pfam PF01676 Metalloenzyme superfamily 2 397 3.7E-50 T 01-11-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 AFULGI_00020020 ba1af87983f9afe1cd07e316b94bf522 408 Hamap MF_01402_A 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [apgM]. 1 399 48.292 T 01-11-2018 IPR023665 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, prokaryotes GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFULGI_00020020 ba1af87983f9afe1cd07e316b94bf522 408 Gene3D G3DSA:3.30.70.2130 75 229 6.8E-139 T 01-11-2018 AFULGI_00020020 ba1af87983f9afe1cd07e316b94bf522 408 Pfam PF10143 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 34 207 8.8E-59 T 01-11-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFULGI_00020020 ba1af87983f9afe1cd07e316b94bf522 408 Gene3D G3DSA:3.40.720.10 4 394 6.8E-139 T 01-11-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 AFULGI_00020010 5d54b30f2faf94fd54165f895ffd705f 109 PRINTS PR00340 P-II protein signature 52 75 3.0E-39 T 01-11-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AFULGI_00020010 5d54b30f2faf94fd54165f895ffd705f 109 PRINTS PR00340 P-II protein signature 2 17 3.0E-39 T 01-11-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AFULGI_00020010 5d54b30f2faf94fd54165f895ffd705f 109 PRINTS PR00340 P-II protein signature 23 41 3.0E-39 T 01-11-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AFULGI_00020010 5d54b30f2faf94fd54165f895ffd705f 109 PRINTS PR00340 P-II protein signature 83 103 3.0E-39 T 01-11-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AFULGI_00020010 5d54b30f2faf94fd54165f895ffd705f 109 Gene3D G3DSA:3.30.70.120 1 109 3.9E-45 T 01-11-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal AFULGI_00020010 5d54b30f2faf94fd54165f895ffd705f 109 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 4.6E-38 T 01-11-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AFULGI_00020010 5d54b30f2faf94fd54165f895ffd705f 109 SUPERFAMILY SSF54913 1 107 2.64E-39 T 01-11-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta AFULGI_00020010 5d54b30f2faf94fd54165f895ffd705f 109 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 01-11-2018 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 AFULGI_00020010 5d54b30f2faf94fd54165f895ffd705f 109 SMART SM00938 4 105 7.4E-56 T 01-11-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AFULGI_00000050 c64c0e629447cb00e4adcd97ec53c304 417 SUPERFAMILY SSF51726 7 417 7.32E-46 T 01-11-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 AFULGI_00000050 c64c0e629447cb00e4adcd97ec53c304 417 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 172 414 6.2E-19 T 01-11-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 AFULGI_00020660 a10d2dae6a338a8c923618d53d380ba7 449 Gene3D G3DSA:1.10.8.60 358 447 1.3E-26 T 01-11-2018 AFULGI_00020660 a10d2dae6a338a8c923618d53d380ba7 449 Gene3D G3DSA:2.40.50.360 119 246 3.2E-111 T 01-11-2018 AFULGI_00020660 a10d2dae6a338a8c923618d53d380ba7 449 SUPERFAMILY SSF52540 37 428 5.32E-38 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00020660 a10d2dae6a338a8c923618d53d380ba7 449 SMART SM00382 62 357 1.8E-9 T 01-11-2018 IPR003593 AAA+ ATPase domain AFULGI_00020660 a10d2dae6a338a8c923618d53d380ba7 449 Pfam PF06068 TIP49 C-terminus 14 406 9.7E-176 T 01-11-2018 IPR010339 TIP49, C-terminal GO:0003678|GO:0005524 Reactome: R-HSA-171319|Reactome: R-HSA-3214847 AFULGI_00020660 a10d2dae6a338a8c923618d53d380ba7 449 Gene3D G3DSA:3.40.50.300 17 353 3.2E-111 T 01-11-2018 AFULGI_00016710 0e5f23e79fb420fafa0b0eaa16639f78 139 Pfam PF04033 Domain of unknown function (DUF365) 41 138 3.8E-46 T 01-11-2018 IPR007176 Protein of unknown function DUF365 AFULGI_00016710 0e5f23e79fb420fafa0b0eaa16639f78 139 PIRSF PIRSF006031 2 139 2.0E-66 T 01-11-2018 IPR007176 Protein of unknown function DUF365 AFULGI_00016710 0e5f23e79fb420fafa0b0eaa16639f78 139 Gene3D G3DSA:2.30.130.30 1 139 7.5E-65 T 01-11-2018 AFULGI_00016710 0e5f23e79fb420fafa0b0eaa16639f78 139 ProDom PD020174 PH0907 MJECS03 PLASMID PF0569 AF2351 41 139 3.0E-38 T 01-11-2018 IPR007176 Protein of unknown function DUF365 AFULGI_00009820 282deafe261e02147cde4202806a7384 334 SUPERFAMILY SSF55874 201 331 1.17E-26 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFULGI_00009820 282deafe261e02147cde4202806a7384 334 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 17 128 1.7E-18 T 01-11-2018 IPR000014 PAS domain AFULGI_00009820 282deafe261e02147cde4202806a7384 334 Gene3D G3DSA:3.30.450.20 10 136 2.4E-20 T 01-11-2018 AFULGI_00009820 282deafe261e02147cde4202806a7384 334 Pfam PF13426 PAS domain 19 121 7.2E-14 T 01-11-2018 IPR000014 PAS domain AFULGI_00009820 282deafe261e02147cde4202806a7384 334 Gene3D G3DSA:3.30.565.10 199 334 2.5E-28 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFULGI_00009820 282deafe261e02147cde4202806a7384 334 SMART SM00091 7 73 7.5E-4 T 01-11-2018 IPR000014 PAS domain AFULGI_00009820 282deafe261e02147cde4202806a7384 334 SUPERFAMILY SSF55785 12 121 9.77E-18 T 01-11-2018 IPR035965 PAS domain superfamily AFULGI_00009820 282deafe261e02147cde4202806a7384 334 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 232 332 1.8E-21 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFULGI_00009820 282deafe261e02147cde4202806a7384 334 PRINTS PR00344 Bacterial sensor protein C-terminal signature 317 330 1.7E-11 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFULGI_00009820 282deafe261e02147cde4202806a7384 334 PRINTS PR00344 Bacterial sensor protein C-terminal signature 293 311 1.7E-11 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFULGI_00009820 282deafe261e02147cde4202806a7384 334 PRINTS PR00344 Bacterial sensor protein C-terminal signature 265 279 1.7E-11 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFULGI_00009820 282deafe261e02147cde4202806a7384 334 SMART SM00086 82 122 0.0076 T 01-11-2018 IPR001610 PAC motif AFULGI_00009820 282deafe261e02147cde4202806a7384 334 SMART SM00387 229 333 6.1E-25 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFULGI_00026690 a6b57274549e7d1d3663c8a647930a8c 766 Pfam PF09369 Domain of unknown function (DUF1998) 645 718 2.3E-7 T 01-11-2018 IPR018973 DEAD/DEAH-box helicase, putative AFULGI_00026690 a6b57274549e7d1d3663c8a647930a8c 766 SMART SM00490 311 390 4.3E-22 T 01-11-2018 IPR001650 Helicase, C-terminal AFULGI_00026690 a6b57274549e7d1d3663c8a647930a8c 766 Pfam PF00270 DEAD/DEAH box helicase 88 249 1.5E-25 T 01-11-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 AFULGI_00026690 a6b57274549e7d1d3663c8a647930a8c 766 Gene3D G3DSA:3.40.50.300 275 476 7.9E-30 T 01-11-2018 AFULGI_00026690 a6b57274549e7d1d3663c8a647930a8c 766 Gene3D G3DSA:3.40.50.300 63 262 2.5E-41 T 01-11-2018 AFULGI_00026690 a6b57274549e7d1d3663c8a647930a8c 766 SMART SM00487 82 280 1.2E-37 T 01-11-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFULGI_00026690 a6b57274549e7d1d3663c8a647930a8c 766 SUPERFAMILY SSF52540 97 399 5.74E-49 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00026690 a6b57274549e7d1d3663c8a647930a8c 766 Pfam PF00271 Helicase conserved C-terminal domain 290 390 4.4E-19 T 01-11-2018 IPR001650 Helicase, C-terminal AFULGI_00026620 643eec8a499a928bf0911a5572a97897 224 Pfam PF00588 SpoU rRNA Methylase family 78 217 5.2E-37 T 01-11-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 AFULGI_00026620 643eec8a499a928bf0911a5572a97897 224 SUPERFAMILY SSF75217 71 223 1.83E-40 T 01-11-2018 IPR029028 Alpha/beta knot methyltransferases AFULGI_00026620 643eec8a499a928bf0911a5572a97897 224 Gene3D G3DSA:3.40.1280.10 60 224 7.0E-47 T 01-11-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal AFULGI_00026620 643eec8a499a928bf0911a5572a97897 224 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 3 223 6.9E-73 T 01-11-2018 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 Reactome: R-HSA-6793080 AFULGI_00026520 0c9ccce49b937b9f94497c248cf1820d 129 Pfam PF06677 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) 17 52 3.7E-14 T 01-11-2018 IPR009563 Sjoegren syndrome/scleroderma autoantigen 1 AFULGI_00026520 0c9ccce49b937b9f94497c248cf1820d 129 Hamap MF_00343 UPF0148 protein . 10 129 25.432 T 01-11-2018 IPR022954 Uncharacterised protein family UPF0148 AFULGI_00007090 6017e51a7f837c14cd98d2c10d7ccb16 161 Hamap MF_01032 Methanogen homoaconitase small subunit [hacB]. 1 159 39.647 T 01-11-2018 IPR011827 Hydrolyase LeuD/HacB/DmdB GO:0016836 KEGG: 00290+4.2.1.33 AFULGI_00007090 6017e51a7f837c14cd98d2c10d7ccb16 161 Gene3D G3DSA:3.20.19.10 1 160 4.1E-59 T 01-11-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 AFULGI_00007090 6017e51a7f837c14cd98d2c10d7ccb16 161 TIGRFAM TIGR02087 LEUD_arch: 3-isopropylmalate dehydratase, small subunit 2 155 2.8E-66 T 01-11-2018 IPR011827 Hydrolyase LeuD/HacB/DmdB GO:0016836 KEGG: 00290+4.2.1.33 AFULGI_00007090 6017e51a7f837c14cd98d2c10d7ccb16 161 Pfam PF00694 Aconitase C-terminal domain 45 103 2.2E-21 T 01-11-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 AFULGI_00007090 6017e51a7f837c14cd98d2c10d7ccb16 161 SUPERFAMILY SSF52016 2 155 2.35E-50 T 01-11-2018 AFULGI_00008220 ab58ca005298356577402c57189a483d 137 TIGRFAM TIGR00149 TIGR00149_YjbQ: secondary thiamine-phosphate synthase enzyme 14 133 8.4E-29 T 01-11-2018 IPR001602 Uncharacterised protein family UPF0047 AFULGI_00008220 ab58ca005298356577402c57189a483d 137 Pfam PF01894 Uncharacterised protein family UPF0047 17 133 3.3E-32 T 01-11-2018 IPR001602 Uncharacterised protein family UPF0047 AFULGI_00008220 ab58ca005298356577402c57189a483d 137 SUPERFAMILY SSF111038 2 133 7.06E-38 T 01-11-2018 IPR035917 YjbQ-like superfamily AFULGI_00008220 ab58ca005298356577402c57189a483d 137 Gene3D G3DSA:2.60.120.460 1 135 3.1E-39 T 01-11-2018 IPR035917 YjbQ-like superfamily AFULGI_00008220 ab58ca005298356577402c57189a483d 137 PIRSF PIRSF004681 2 136 3.0E-39 T 01-11-2018 IPR001602 Uncharacterised protein family UPF0047 AFULGI_00023220 b647630214a1f55a6adc69264e818110 82 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 33 44 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFULGI_00023220 b647630214a1f55a6adc69264e818110 82 Gene3D G3DSA:3.30.70.20 3 82 9.6E-13 T 01-11-2018 AFULGI_00023220 b647630214a1f55a6adc69264e818110 82 SUPERFAMILY SSF54862 14 81 1.27E-18 T 01-11-2018 AFULGI_00023220 b647630214a1f55a6adc69264e818110 82 Pfam PF13187 4Fe-4S dicluster domain 32 76 1.3E-7 T 01-11-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFULGI_00023220 b647630214a1f55a6adc69264e818110 82 TIGRFAM TIGR02179 PorD_KorD: 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate family 8 82 2.4E-31 T 01-11-2018 IPR011898 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0051539 AFULGI_00005650 1158cf3167afc05a036ca31360d7b18a 127 Gene3D G3DSA:3.40.1260.10 1 127 7.5E-26 T 01-11-2018 IPR027396 DsrEFH-like AFULGI_00005650 1158cf3167afc05a036ca31360d7b18a 127 SUPERFAMILY SSF75169 1 122 2.55E-14 T 01-11-2018 IPR027396 DsrEFH-like AFULGI_00005650 1158cf3167afc05a036ca31360d7b18a 127 Pfam PF13686 DsrE/DsrF/DrsH-like family 2 49 1.2E-6 T 01-11-2018 IPR032836 DsrE2-like family AFULGI_00005650 1158cf3167afc05a036ca31360d7b18a 127 Pfam PF13686 DsrE/DsrF/DrsH-like family 60 124 2.3E-7 T 01-11-2018 IPR032836 DsrE2-like family AFULGI_00003620 c627d6956f9f3f6b8f000cd5eeb847a0 305 SUPERFAMILY SSF51735 2 299 6.67E-82 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily AFULGI_00003620 c627d6956f9f3f6b8f000cd5eeb847a0 305 Pfam PF01370 NAD dependent epimerase/dehydratase family 2 228 4.0E-51 T 01-11-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 AFULGI_00003620 c627d6956f9f3f6b8f000cd5eeb847a0 305 Gene3D G3DSA:3.90.25.10 168 288 6.7E-115 T 01-11-2018 AFULGI_00003620 c627d6956f9f3f6b8f000cd5eeb847a0 305 Gene3D G3DSA:3.40.50.720 2 228 6.7E-115 T 01-11-2018 AFULGI_00021780 f4daf7127f7e071b801997b8328a0b36 229 SUPERFAMILY SSF54821 85 185 1.7E-25 T 01-11-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00021780 f4daf7127f7e071b801997b8328a0b36 229 Gene3D G3DSA:3.30.300.20 1 85 8.2E-23 T 01-11-2018 IPR015946 K homology domain-like, alpha/beta AFULGI_00021780 f4daf7127f7e071b801997b8328a0b36 229 Pfam PF00189 Ribosomal protein S3, C-terminal domain 98 181 3.8E-23 T 01-11-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00021780 f4daf7127f7e071b801997b8328a0b36 229 Pfam PF07650 KH domain 17 88 1.3E-12 T 01-11-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00021780 f4daf7127f7e071b801997b8328a0b36 229 Hamap MF_01309_A 30S ribosomal protein S3 [rpsC]. 2 196 41.638 T 01-11-2018 IPR027488 Ribosomal protein S3, archaeal GO:0003735|GO:0006412|GO:0015935 AFULGI_00021780 f4daf7127f7e071b801997b8328a0b36 229 SMART SM00322 38 103 1.7E-6 T 01-11-2018 IPR004087 K Homology domain GO:0003676 AFULGI_00021780 f4daf7127f7e071b801997b8328a0b36 229 Gene3D G3DSA:3.30.1140.32 88 225 6.1E-36 T 01-11-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00021780 f4daf7127f7e071b801997b8328a0b36 229 SUPERFAMILY SSF54814 6 94 1.31E-20 T 01-11-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 AFULGI_00021780 f4daf7127f7e071b801997b8328a0b36 229 TIGRFAM TIGR01008 uS3_euk_arch: ribosomal protein uS3 3 196 7.2E-91 T 01-11-2018 IPR005703 Ribosomal protein S3, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00010310 006fc6da07e18f5c2736e28b0ccb5be7 114 Pfam PF14591 AF0941-like 1 113 1.4E-37 T 01-11-2018 IPR013502 Uncharacterised domain AF0941 AFULGI_00010310 006fc6da07e18f5c2736e28b0ccb5be7 114 SUPERFAMILY SSF140726 1 114 2.09E-71 T 01-11-2018 IPR036564 AF0941-like superfamily AFULGI_00010310 006fc6da07e18f5c2736e28b0ccb5be7 114 Gene3D G3DSA:1.10.3200.10 1 114 1.9E-59 T 01-11-2018 IPR036564 AF0941-like superfamily AFULGI_00021540 ee772d21166ec8001ab8aa93d378bb85 209 Pfam PF03692 Putative zinc- or iron-chelating domain 19 120 3.1E-14 T 01-11-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein AFULGI_00008550 e2c28cea20f812dee93946473cebc67e 253 Gene3D G3DSA:3.40.50.300 1 211 1.3E-37 T 01-11-2018 AFULGI_00008550 e2c28cea20f812dee93946473cebc67e 253 Pfam PF06745 KaiC 5 210 1.5E-32 T 01-11-2018 IPR014774 KaiC-like domain AFULGI_00008550 e2c28cea20f812dee93946473cebc67e 253 SUPERFAMILY SSF52540 2 207 6.15E-32 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00016520 17684447299a5d92cc6551fada3489a9 64 SUPERFAMILY SSF141694 1 47 3.66E-12 T 01-11-2018 AFULGI_00016520 17684447299a5d92cc6551fada3489a9 64 Pfam PF01954 Protein of unknown function DUF104 1 55 1.1E-15 T 01-11-2018 IPR008203 Uncharacterised protein family UPF0165 AFULGI_00016520 17684447299a5d92cc6551fada3489a9 64 Gene3D G3DSA:4.10.1150.10 1 59 2.7E-12 T 01-11-2018 IPR024069 AF2212-like domain superfamily AFULGI_00024410 bfe0061a99630cecf1711d308b71ff79 324 Pfam PF13854 Kelch motif 264 297 6.7E-6 T 01-11-2018 AFULGI_00024410 bfe0061a99630cecf1711d308b71ff79 324 SUPERFAMILY SSF117281 84 305 5.89E-26 T 01-11-2018 IPR015915 Kelch-type beta propeller GO:0005515 AFULGI_00024410 bfe0061a99630cecf1711d308b71ff79 324 Gene3D G3DSA:2.120.10.80 68 317 3.5E-21 T 01-11-2018 IPR015915 Kelch-type beta propeller GO:0005515 AFULGI_00018870 751e0f2d965f290a18ab3cafaf3527dd 379 SUPERFAMILY SSF51905 1 338 9.72E-22 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFULGI_00018870 751e0f2d965f290a18ab3cafaf3527dd 379 Gene3D G3DSA:3.30.9.10 75 346 4.4E-54 T 01-11-2018 AFULGI_00018870 751e0f2d965f290a18ab3cafaf3527dd 379 TIGRFAM TIGR02032 GG-red-SF: geranylgeranyl reductase family 1 296 9.9E-75 T 01-11-2018 IPR011777 Geranylgeranyl reductase family GO:0016628|GO:0055114 AFULGI_00018870 751e0f2d965f290a18ab3cafaf3527dd 379 Gene3D G3DSA:3.50.50.60 2 331 4.4E-54 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFULGI_00006150 6f73757bce2714a91a674420590091dd 510 Pfam PF00753 Metallo-beta-lactamase superfamily 88 186 5.9E-5 T 01-11-2018 IPR001279 Metallo-beta-lactamase AFULGI_00006150 6f73757bce2714a91a674420590091dd 510 SUPERFAMILY SSF56281 4 509 3.14E-40 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFULGI_00006150 6f73757bce2714a91a674420590091dd 510 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 459 488 1.6E-5 T 01-11-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain AFULGI_00006360 750eea5948f02dadaffa04098f8b00b9 135 Gene3D G3DSA:3.40.50.1010 2 126 4.1E-29 T 01-11-2018 AFULGI_00006360 750eea5948f02dadaffa04098f8b00b9 135 SUPERFAMILY SSF88723 2 124 1.26E-14 T 01-11-2018 IPR029060 PIN-like domain superfamily AFULGI_00006360 750eea5948f02dadaffa04098f8b00b9 135 Pfam PF01850 PIN domain 3 119 3.1E-10 T 01-11-2018 IPR002716 PIN domain AFULGI_00024220 92d6ad7c69540574b733087aeb1c02de 125 Pfam PF01201 Ribosomal protein S8e 2 124 6.1E-33 T 01-11-2018 IPR022309 Ribosomal protein S8e/ribosomal biogenesis NSA2 AFULGI_00024220 92d6ad7c69540574b733087aeb1c02de 125 TIGRFAM TIGR00307 eS8: ribosomal protein eS8 1 125 2.6E-61 T 01-11-2018 IPR001047 Ribosomal protein S8e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00024220 92d6ad7c69540574b733087aeb1c02de 125 ProSitePatterns PS01193 Ribosomal protein S8e signature. 9 28 - T 01-11-2018 IPR018283 Ribosomal protein S8e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00024220 92d6ad7c69540574b733087aeb1c02de 125 Hamap MF_00029 30S ribosomal protein S8e [rps8e]. 1 125 32.035 T 01-11-2018 IPR020919 Ribosomal protein S8e, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFULGI_00024220 92d6ad7c69540574b733087aeb1c02de 125 Gene3D G3DSA:2.40.10.310 57 125 4.0E-31 T 01-11-2018 AFULGI_00015400 95c68ac72227e37ef68fbe92157c827e 244 ProSitePatterns PS00221 MIP family signature. 79 87 - T 01-11-2018 IPR022357 Major intrinsic protein, conserved site Reactome: R-HSA-432047 AFULGI_00015400 95c68ac72227e37ef68fbe92157c827e 244 PRINTS PR00783 Major intrinsic protein family signature 61 85 3.7E-46 T 01-11-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 AFULGI_00015400 95c68ac72227e37ef68fbe92157c827e 244 PRINTS PR00783 Major intrinsic protein family signature 5 24 3.7E-46 T 01-11-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 AFULGI_00015400 95c68ac72227e37ef68fbe92157c827e 244 PRINTS PR00783 Major intrinsic protein family signature 221 241 3.7E-46 T 01-11-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 AFULGI_00015400 95c68ac72227e37ef68fbe92157c827e 244 PRINTS PR00783 Major intrinsic protein family signature 148 166 3.7E-46 T 01-11-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 AFULGI_00015400 95c68ac72227e37ef68fbe92157c827e 244 PRINTS PR00783 Major intrinsic protein family signature 179 201 3.7E-46 T 01-11-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 AFULGI_00015400 95c68ac72227e37ef68fbe92157c827e 244 PRINTS PR00783 Major intrinsic protein family signature 98 117 3.7E-46 T 01-11-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 AFULGI_00015400 95c68ac72227e37ef68fbe92157c827e 244 SUPERFAMILY SSF81338 3 241 2.49E-61 T 01-11-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 AFULGI_00015400 95c68ac72227e37ef68fbe92157c827e 244 TIGRFAM TIGR00861 MIP: MIP family channel proteins 9 238 4.3E-64 T 01-11-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 AFULGI_00015400 95c68ac72227e37ef68fbe92157c827e 244 Pfam PF00230 Major intrinsic protein 3 238 3.0E-48 T 01-11-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 AFULGI_00015400 95c68ac72227e37ef68fbe92157c827e 244 Gene3D G3DSA:1.20.1080.10 1 244 2.7E-96 T 01-11-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 AFULGI_00006550 54372358a9f02240b76557777a087f73 307 SUPERFAMILY SSF55785 22 125 4.03E-10 T 01-11-2018 IPR035965 PAS domain superfamily AFULGI_00006550 54372358a9f02240b76557777a087f73 307 Gene3D G3DSA:3.30.450.20 4 128 4.3E-11 T 01-11-2018 AFULGI_00014980 0d99090402d9b40c54bd9bc3d9b80174 86 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 4 48 4.3E-12 T 01-11-2018 IPR007159 SpoVT-AbrB domain GO:0003677 AFULGI_00014980 0d99090402d9b40c54bd9bc3d9b80174 86 SMART SM00966 4 49 9.9E-15 T 01-11-2018 IPR007159 SpoVT-AbrB domain GO:0003677 AFULGI_00014980 0d99090402d9b40c54bd9bc3d9b80174 86 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 3 44 8.1E-16 T 01-11-2018 IPR007159 SpoVT-AbrB domain GO:0003677 AFULGI_00014980 0d99090402d9b40c54bd9bc3d9b80174 86 Gene3D G3DSA:2.10.260.10 3 42 1.0E-13 T 01-11-2018 AFULGI_00014980 0d99090402d9b40c54bd9bc3d9b80174 86 SUPERFAMILY SSF89447 3 45 1.16E-12 T 01-11-2018 IPR037914 SpoVT-AbrB domain superfamily AFULGI_00022940 3f4e04a899848f9e4e1671c53b9ba1d3 473 Gene3D G3DSA:3.90.1640.10 157 336 1.0E-32 T 01-11-2018 AFULGI_00022940 3f4e04a899848f9e4e1671c53b9ba1d3 473 SUPERFAMILY SSF64182 158 439 1.31E-62 T 01-11-2018 IPR038763 DHH phosphoesterase superfamily AFULGI_00022940 3f4e04a899848f9e4e1671c53b9ba1d3 473 Pfam PF02272 DHHA1 domain 351 455 1.2E-16 T 01-11-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 AFULGI_00022940 3f4e04a899848f9e4e1671c53b9ba1d3 473 SUPERFAMILY SSF51735 8 130 3.13E-19 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily AFULGI_00022940 3f4e04a899848f9e4e1671c53b9ba1d3 473 Gene3D G3DSA:3.40.50.720 2 141 7.7E-31 T 01-11-2018 AFULGI_00022940 3f4e04a899848f9e4e1671c53b9ba1d3 473 Pfam PF01368 DHH family 161 300 1.3E-11 T 01-11-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 AFULGI_00022940 3f4e04a899848f9e4e1671c53b9ba1d3 473 Pfam PF02254 TrkA-N domain 9 121 7.5E-22 T 01-11-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 AFULGI_00016950 9c041861855f07f22ba24241f0184ba5 353 Pfam PF07719 Tetratricopeptide repeat 186 216 1.3E-5 T 01-11-2018 IPR013105 Tetratricopeptide repeat 2 AFULGI_00016950 9c041861855f07f22ba24241f0184ba5 353 Gene3D G3DSA:1.25.40.10 92 246 1.7E-10 T 01-11-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFULGI_00016950 9c041861855f07f22ba24241f0184ba5 353 SMART SM00028 96 129 93.0 T 01-11-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFULGI_00016950 9c041861855f07f22ba24241f0184ba5 353 SMART SM00028 184 217 0.067 T 01-11-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFULGI_00016950 9c041861855f07f22ba24241f0184ba5 353 SUPERFAMILY SSF48452 88 230 9.48E-9 T 01-11-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFULGI_00004490 aa5b6eb6a1c73dc812b3ca04b823becf 161 Pfam PF03692 Putative zinc- or iron-chelating domain 12 109 8.3E-13 T 01-11-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein AFULGI_00019550 787c0d53c697ac69a7def7a88d01220d 232 Gene3D G3DSA:3.40.50.1820 3 232 4.8E-53 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold AFULGI_00019550 787c0d53c697ac69a7def7a88d01220d 232 SUPERFAMILY SSF53474 4 228 6.87E-57 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold AFULGI_00019550 787c0d53c697ac69a7def7a88d01220d 232 PRINTS PR00111 Alpha/beta hydrolase fold signature 202 216 3.5E-12 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 AFULGI_00019550 787c0d53c697ac69a7def7a88d01220d 232 PRINTS PR00111 Alpha/beta hydrolase fold signature 47 62 3.5E-12 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 AFULGI_00019550 787c0d53c697ac69a7def7a88d01220d 232 PRINTS PR00111 Alpha/beta hydrolase fold signature 104 117 3.5E-12 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 AFULGI_00019550 787c0d53c697ac69a7def7a88d01220d 232 PRINTS PR00111 Alpha/beta hydrolase fold signature 90 103 3.5E-12 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 AFULGI_00019550 787c0d53c697ac69a7def7a88d01220d 232 Pfam PF00561 alpha/beta hydrolase fold 23 130 2.9E-23 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 AFULGI_00001050 b97e3f787ca2711d37fd2b92fec1db70 265 Hamap MF_00960 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [aroA']. 3 264 65.236 T 01-11-2018 IPR010210 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase GO:0009073|GO:0016836 KEGG: 00400+2.2.1.10|MetaCyc: PWY-6160 AFULGI_00001050 b97e3f787ca2711d37fd2b92fec1db70 265 Pfam PF01791 DeoC/LacD family aldolase 21 235 4.5E-67 T 01-11-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 AFULGI_00001050 b97e3f787ca2711d37fd2b92fec1db70 265 Gene3D G3DSA:3.20.20.70 1 265 1.2E-94 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFULGI_00001050 b97e3f787ca2711d37fd2b92fec1db70 265 SUPERFAMILY SSF51569 5 252 1.32E-81 T 01-11-2018 AFULGI_00001050 b97e3f787ca2711d37fd2b92fec1db70 265 TIGRFAM TIGR01949 AroFGH_arch: predicted phospho-2-dehydro-3-deoxyheptonate aldolase 4 261 9.5E-117 T 01-11-2018 IPR010210 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase GO:0009073|GO:0016836 KEGG: 00400+2.2.1.10|MetaCyc: PWY-6160 AFULGI_00001050 b97e3f787ca2711d37fd2b92fec1db70 265 SMART SM01133 21 236 1.9E-68 T 01-11-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 AFULGI_00001050 b97e3f787ca2711d37fd2b92fec1db70 265 PIRSF PIRSF038992 1 265 1.3E-95 T 01-11-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 AFULGI_00010100 782767d117d34c169fc3d375f6ffcf3b 336 Gene3D G3DSA:1.10.3940.10 206 336 1.9E-86 T 01-11-2018 AFULGI_00010100 782767d117d34c169fc3d375f6ffcf3b 336 Gene3D G3DSA:3.30.460.10 65 205 2.0E-5 T 01-11-2018 AFULGI_00010100 782767d117d34c169fc3d375f6ffcf3b 336 SUPERFAMILY SSF81301 82 220 3.6E-11 T 01-11-2018 AFULGI_00008240 d101238435066619bbd6aaceae3fe42d 138 SUPERFAMILY SSF55021 55 132 6.64E-25 T 01-11-2018 AFULGI_00008240 d101238435066619bbd6aaceae3fe42d 138 Hamap MF_00476 Nickel-responsive regulator [nikR]. 5 136 29.115 T 01-11-2018 IPR022988 Nickel-responsive transcriptional regulator NikR GO:0003677|GO:0006355|GO:0010045|GO:0016151 AFULGI_00008240 d101238435066619bbd6aaceae3fe42d 138 Pfam PF01402 Ribbon-helix-helix protein, copG family 7 45 4.4E-10 T 01-11-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 AFULGI_00008240 d101238435066619bbd6aaceae3fe42d 138 Pfam PF08753 NikR C terminal nickel binding domain 58 132 4.9E-29 T 01-11-2018 IPR014864 Transcription factor, NikR, nickel binding C-terminal AFULGI_00008240 d101238435066619bbd6aaceae3fe42d 138 Gene3D G3DSA:1.10.1220.10 12 48 9.2E-19 T 01-11-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 AFULGI_00008240 d101238435066619bbd6aaceae3fe42d 138 SUPERFAMILY SSF47598 5 51 1.93E-14 T 01-11-2018 IPR010985 Ribbon-helix-helix GO:0006355 AFULGI_00008240 d101238435066619bbd6aaceae3fe42d 138 Gene3D G3DSA:3.30.70.1150 49 137 3.1E-29 T 01-11-2018 IPR027271 Acetolactate synthase/Transcription factor NikR, C-terminal AFULGI_00023630 99d0f97b00a89ba5f809a39b48177f8b 115 TIGRFAM TIGR00283 arch_pth2: peptidyl-tRNA hydrolase 3 114 5.8E-52 T 01-11-2018 IPR002833 Peptidyl-tRNA hydrolase, PTH2 GO:0004045 MetaCyc: PWY-6308 AFULGI_00023630 99d0f97b00a89ba5f809a39b48177f8b 115 Gene3D G3DSA:3.40.1490.10 1 115 1.7E-47 T 01-11-2018 IPR023476 Peptidyl-tRNA hydrolase II domain superfamily MetaCyc: PWY-6308 AFULGI_00023630 99d0f97b00a89ba5f809a39b48177f8b 115 Hamap MF_00628 Peptidyl-tRNA hydrolase [pth]. 3 115 31.166 T 01-11-2018 IPR034759 Peptidyl-tRNA hydrolase, archaea GO:0004045 MetaCyc: PWY-6308 AFULGI_00023630 99d0f97b00a89ba5f809a39b48177f8b 115 SUPERFAMILY SSF102462 3 114 4.88E-39 T 01-11-2018 IPR023476 Peptidyl-tRNA hydrolase II domain superfamily MetaCyc: PWY-6308 AFULGI_00023630 99d0f97b00a89ba5f809a39b48177f8b 115 Pfam PF01981 Peptidyl-tRNA hydrolase PTH2 3 114 3.2E-36 T 01-11-2018 IPR002833 Peptidyl-tRNA hydrolase, PTH2 GO:0004045 MetaCyc: PWY-6308 AFULGI_00023170 f7b318ecb8428f74ad1b71eb8df1ebbd 378 Gene3D G3DSA:3.40.50.300 64 246 1.3E-10 T 01-11-2018 AFULGI_00023170 f7b318ecb8428f74ad1b71eb8df1ebbd 378 Pfam PF16575 mRNA cleavage and polyadenylation factor CLP1 P-loop 80 238 1.3E-22 T 01-11-2018 IPR032319 Polyribonucleotide 5'-hydroxyl-kinase Clp1, P-loop domain AFULGI_00023170 f7b318ecb8428f74ad1b71eb8df1ebbd 378 SUPERFAMILY SSF52540 65 102 1.87E-5 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00023170 f7b318ecb8428f74ad1b71eb8df1ebbd 378 SUPERFAMILY SSF52540 75 271 8.62E-5 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00015090 e65df8656d8bbca1ffd8347d9a7c9def 806 Gene3D G3DSA:2.60.40.10 229 318 7.2E-26 T 01-11-2018 IPR013783 Immunoglobulin-like fold AFULGI_00015090 e65df8656d8bbca1ffd8347d9a7c9def 806 SMART SM00089 237 319 5.6E-29 T 01-11-2018 IPR022409 PKD/Chitinase domain AFULGI_00015090 e65df8656d8bbca1ffd8347d9a7c9def 806 Gene3D G3DSA:1.50.10.20 592 734 8.5E-23 T 01-11-2018 AFULGI_00015090 e65df8656d8bbca1ffd8347d9a7c9def 806 Gene3D G3DSA:1.50.10.20 412 591 1.5E-14 T 01-11-2018 AFULGI_00015090 e65df8656d8bbca1ffd8347d9a7c9def 806 Gene3D G3DSA:3.10.20.490 115 201 5.7E-5 T 01-11-2018 AFULGI_00015090 e65df8656d8bbca1ffd8347d9a7c9def 806 Pfam PF13243 Squalene-hopene cyclase C-terminal domain 597 723 3.3E-8 T 01-11-2018 IPR032696 Squalene cyclase, C-terminal Reactome: R-HSA-191273|Reactome: R-HSA-2426168 AFULGI_00015090 e65df8656d8bbca1ffd8347d9a7c9def 806 Pfam PF13243 Squalene-hopene cyclase C-terminal domain 456 526 9.8E-7 T 01-11-2018 IPR032696 Squalene cyclase, C-terminal Reactome: R-HSA-191273|Reactome: R-HSA-2426168 AFULGI_00015090 e65df8656d8bbca1ffd8347d9a7c9def 806 SUPERFAMILY SSF48239 457 605 1.36E-13 T 01-11-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid AFULGI_00015090 e65df8656d8bbca1ffd8347d9a7c9def 806 Pfam PF14478 Domain of unknown function (DUF4430) 124 200 1.9E-5 T 01-11-2018 IPR027954 Domain of unknown function DUF4430 Reactome: R-HSA-196741 AFULGI_00015090 e65df8656d8bbca1ffd8347d9a7c9def 806 Pfam PF00801 PKD domain 244 308 8.0E-18 T 01-11-2018 IPR000601 PKD domain AFULGI_00015090 e65df8656d8bbca1ffd8347d9a7c9def 806 SUPERFAMILY SSF49299 234 319 1.19E-23 T 01-11-2018 IPR035986 PKD domain superfamily AFULGI_00015090 e65df8656d8bbca1ffd8347d9a7c9def 806 TIGRFAM TIGR04213 PGF_pre_PGF: PGF-pre-PGF domain 371 449 5.1E-11 T 01-11-2018 IPR026453 PGF-pre-PGF domain AFULGI_00015090 e65df8656d8bbca1ffd8347d9a7c9def 806 SUPERFAMILY SSF48239 570 716 5.83E-26 T 01-11-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid AFULGI_00009010 f85fb1ea4d56fe3a3f9fe903bec489ba 346 SUPERFAMILY SSF53335 2 344 2.57E-91 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFULGI_00009010 f85fb1ea4d56fe3a3f9fe903bec489ba 346 TIGRFAM TIGR00308 TRM1: N2,N2-dimethylguanosine tRNA methyltransferase 3 344 5.4E-148 T 01-11-2018 IPR002905 tRNA methyltransferase, Trm1 GO:0003723|GO:0004809|GO:0008033 MetaCyc: PWY-6829 AFULGI_00009010 f85fb1ea4d56fe3a3f9fe903bec489ba 346 Hamap MF_00290 tRNA (guanine(26)-N(2))-dimethyltransferase [trm1]. 1 345 39.503 T 01-11-2018 IPR022923 tRNA (guanine(26)-N(2))-dimethyltransferase, archaeal and bacterial GO:0004809 MetaCyc: PWY-6829 AFULGI_00009010 f85fb1ea4d56fe3a3f9fe903bec489ba 346 Pfam PF02005 N2,N2-dimethylguanosine tRNA methyltransferase 12 343 7.7E-121 T 01-11-2018 IPR002905 tRNA methyltransferase, Trm1 GO:0003723|GO:0004809|GO:0008033 MetaCyc: PWY-6829 AFULGI_00009010 f85fb1ea4d56fe3a3f9fe903bec489ba 346 Gene3D G3DSA:3.40.50.150 1 286 3.2E-81 T 01-11-2018 AFULGI_00009010 f85fb1ea4d56fe3a3f9fe903bec489ba 346 Gene3D G3DSA:3.30.56.70 287 345 1.2E-13 T 01-11-2018 AFULGI_00015010 8ccf1a219738a10ff30dcd5cc70f9aa8 257 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFULGI_00015010 8ccf1a219738a10ff30dcd5cc70f9aa8 257 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 226 247 1.0E-7 T 01-11-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal AFULGI_00015010 8ccf1a219738a10ff30dcd5cc70f9aa8 257 SUPERFAMILY SSF52540 3 248 1.47E-60 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00015010 8ccf1a219738a10ff30dcd5cc70f9aa8 257 Pfam PF00005 ABC transporter 19 177 9.6E-29 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFULGI_00015010 8ccf1a219738a10ff30dcd5cc70f9aa8 257 Gene3D G3DSA:3.40.50.300 1 248 4.1E-65 T 01-11-2018 AFULGI_00015010 8ccf1a219738a10ff30dcd5cc70f9aa8 257 SMART SM00382 28 225 1.5E-6 T 01-11-2018 IPR003593 AAA+ ATPase domain AFULGI_00014830 0372a341f74764a0365e16128fb32916 135 Pfam PF01750 Hydrogenase maturation protease 40 114 9.6E-5 T 01-11-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 AFULGI_00014830 0372a341f74764a0365e16128fb32916 135 SUPERFAMILY SSF53163 1 115 3.92E-18 T 01-11-2018 IPR023430 Peptidase HybD-like domain superfamily AFULGI_00014830 0372a341f74764a0365e16128fb32916 135 Gene3D G3DSA:3.40.50.1450 1 131 1.2E-16 T 01-11-2018 IPR023430 Peptidase HybD-like domain superfamily AFULGI_00014830 0372a341f74764a0365e16128fb32916 135 TIGRFAM TIGR00072 hydrog_prot: hydrogenase maturation protease 4 112 2.0E-14 T 01-11-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 AFULGI_00025970 511998736ddd7a4c500bc3addddd3e02 280 Gene3D G3DSA:3.90.920.10 8 278 1.0E-47 T 01-11-2018 AFULGI_00025970 511998736ddd7a4c500bc3addddd3e02 280 SUPERFAMILY SSF56747 10 269 4.14E-38 T 01-11-2018 AFULGI_00018890 254cf16be3f15aac08c031ed10e9d009 323 Gene3D G3DSA:3.30.450.20 4 126 7.3E-13 T 01-11-2018 AFULGI_00018890 254cf16be3f15aac08c031ed10e9d009 323 SMART SM00388 126 187 5.0E-7 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFULGI_00018890 254cf16be3f15aac08c031ed10e9d009 323 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 3 119 1.7E-13 T 01-11-2018 IPR000014 PAS domain AFULGI_00018890 254cf16be3f15aac08c031ed10e9d009 323 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 221 318 1.9E-21 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFULGI_00018890 254cf16be3f15aac08c031ed10e9d009 323 SUPERFAMILY SSF47384 113 181 9.61E-6 T 01-11-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFULGI_00018890 254cf16be3f15aac08c031ed10e9d009 323 PRINTS PR00344 Bacterial sensor protein C-terminal signature 253 267 2.0E-12 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFULGI_00018890 254cf16be3f15aac08c031ed10e9d009 323 PRINTS PR00344 Bacterial sensor protein C-terminal signature 271 281 2.0E-12 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFULGI_00018890 254cf16be3f15aac08c031ed10e9d009 323 PRINTS PR00344 Bacterial sensor protein C-terminal signature 304 317 2.0E-12 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFULGI_00018890 254cf16be3f15aac08c031ed10e9d009 323 PRINTS PR00344 Bacterial sensor protein C-terminal signature 281 299 2.0E-12 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFULGI_00018890 254cf16be3f15aac08c031ed10e9d009 323 SUPERFAMILY SSF55785 13 121 2.62E-13 T 01-11-2018 IPR035965 PAS domain superfamily AFULGI_00018890 254cf16be3f15aac08c031ed10e9d009 323 SMART SM00387 218 320 1.7E-28 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFULGI_00018890 254cf16be3f15aac08c031ed10e9d009 323 Pfam PF00989 PAS fold 4 110 4.6E-7 T 01-11-2018 IPR013767 PAS fold GO:0006355 AFULGI_00018890 254cf16be3f15aac08c031ed10e9d009 323 Gene3D G3DSA:3.30.565.10 185 317 1.6E-28 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFULGI_00018890 254cf16be3f15aac08c031ed10e9d009 323 Gene3D G3DSA:1.10.287.130 134 184 1.6E-28 T 01-11-2018 AFULGI_00018890 254cf16be3f15aac08c031ed10e9d009 323 SUPERFAMILY SSF55874 187 320 8.25E-25 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFULGI_00021670 42166973215d072e8a500d77904ff246 129 SMART SM01393 17 126 1.7E-55 T 01-11-2018 IPR001515 Ribosomal protein L32e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00021670 42166973215d072e8a500d77904ff246 129 ProSitePatterns PS00580 Ribosomal protein L32e signature. 20 41 - T 01-11-2018 IPR018263 Ribosomal protein L32e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00021670 42166973215d072e8a500d77904ff246 129 SUPERFAMILY SSF52042 1 128 2.09E-41 T 01-11-2018 IPR036351 Ribosomal protein L32e superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00021670 42166973215d072e8a500d77904ff246 129 ProDom PD003823 RIBOSOMAL L32 RIBONUCLEOPROTEIN 60S L32E 50S L32 STRAIN CHROMOSOME DIRECT 2 127 3.0E-67 T 01-11-2018 IPR001515 Ribosomal protein L32e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00021670 42166973215d072e8a500d77904ff246 129 Hamap MF_00810 50S ribosomal protein L32e [rpl32e]. 1 127 30.398 T 01-11-2018 IPR023654 Ribosomal protein L32e, archaeal GO:0003735|GO:0005840|GO:0006412 AFULGI_00021670 42166973215d072e8a500d77904ff246 129 Pfam PF01655 Ribosomal protein L32 17 126 2.2E-35 T 01-11-2018 IPR001515 Ribosomal protein L32e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00011010 18fb18235d177d827f98f5c1f37590ae 161 SUPERFAMILY SSF46689 25 136 9.86E-23 T 01-11-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFULGI_00011010 18fb18235d177d827f98f5c1f37590ae 161 Pfam PF13565 Homeodomain-like domain 60 132 1.4E-17 T 01-11-2018 AFULGI_00024100 18fb18235d177d827f98f5c1f37590ae 161 SUPERFAMILY SSF46689 25 136 9.86E-23 T 01-11-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFULGI_00024100 18fb18235d177d827f98f5c1f37590ae 161 Pfam PF13565 Homeodomain-like domain 60 132 1.4E-17 T 01-11-2018 AFULGI_00014620 18fb18235d177d827f98f5c1f37590ae 161 SUPERFAMILY SSF46689 25 136 9.86E-23 T 01-11-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFULGI_00014620 18fb18235d177d827f98f5c1f37590ae 161 Pfam PF13565 Homeodomain-like domain 60 132 1.4E-17 T 01-11-2018 AFULGI_00024190 f28529846e0d68fe3cc6cf8002ef2454 211 SUPERFAMILY SSF109755 16 197 3.49E-6 T 01-11-2018 AFULGI_00024190 f28529846e0d68fe3cc6cf8002ef2454 211 TIGRFAM TIGR00153 TIGR00153: TIGR00153 family protein 2 211 2.5E-80 T 01-11-2018 IPR002727 Protein of unknown function DUF47 AFULGI_00024190 f28529846e0d68fe3cc6cf8002ef2454 211 Gene3D G3DSA:1.20.58.220 9 207 1.1E-28 T 01-11-2018 IPR038078 PhoU-like domain superfamily AFULGI_00024190 f28529846e0d68fe3cc6cf8002ef2454 211 Pfam PF01865 Protein of unknown function DUF47 7 207 3.3E-67 T 01-11-2018 IPR018445 Putative phosphate transport regulator AFULGI_00024270 dec86c7b4774019232d921f37909a0cd 176 SUPERFAMILY SSF55144 1 175 1.29E-46 T 01-11-2018 IPR009097 Cyclic phosphodiesterase AFULGI_00024270 dec86c7b4774019232d921f37909a0cd 176 Gene3D G3DSA:3.90.1140.10 1 176 6.8E-56 T 01-11-2018 AFULGI_00024270 dec86c7b4774019232d921f37909a0cd 176 TIGRFAM TIGR02258 2_5_ligase: 2'-5' RNA ligase 1 175 5.3E-59 T 01-11-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 AFULGI_00024270 dec86c7b4774019232d921f37909a0cd 176 Pfam PF02834 LigT like Phosphoesterase 7 88 3.3E-19 T 01-11-2018 IPR014051 Phosphoesterase, HXTX AFULGI_00024270 dec86c7b4774019232d921f37909a0cd 176 Pfam PF02834 LigT like Phosphoesterase 92 169 1.2E-12 T 01-11-2018 IPR014051 Phosphoesterase, HXTX AFULGI_00024270 dec86c7b4774019232d921f37909a0cd 176 Hamap MF_01940 RNA 2',3'-cyclic phosphodiesterase [thpR]. 1 176 24.846 T 01-11-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 AFULGI_00023780 1fbcc4d4262fac837f4037ea9c671c43 241 TIGRFAM TIGR00697 TIGR00697: conserved hypothetical integral membrane protein 26 230 2.1E-83 T 01-11-2018 IPR003744 Queuosine precursor transporter GO:1990397 AFULGI_00023780 1fbcc4d4262fac837f4037ea9c671c43 241 Pfam PF02592 Putative vitamin uptake transporter 58 223 6.3E-54 T 01-11-2018 IPR003744 Queuosine precursor transporter GO:1990397 AFULGI_00023780 1fbcc4d4262fac837f4037ea9c671c43 241 Hamap MF_02088 Probable queuosine precursor transporter. 26 231 17.314 T 01-11-2018 IPR003744 Queuosine precursor transporter GO:1990397 AFULGI_00006420 fbf1fb84ec6a8ad4b6ab1b57c4a416ce 121 SUPERFAMILY SSF144091 9 113 6.93E-6 T 01-11-2018 AFULGI_00007420 64085320b5c5ca3a19374d55c1c1cef8 746 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 565 576 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFULGI_00007420 64085320b5c5ca3a19374d55c1c1cef8 746 Pfam PF02662 Methyl-viologen-reducing hydrogenase, delta subunit 615 739 1.9E-39 T 01-11-2018 IPR003813 F420-non-reducing hydrogenase iron-sulfur subunit D GO:0055114 AFULGI_00007420 64085320b5c5ca3a19374d55c1c1cef8 746 Gene3D G3DSA:3.30.70.20 530 598 7.5E-11 T 01-11-2018 AFULGI_00007420 64085320b5c5ca3a19374d55c1c1cef8 746 Gene3D G3DSA:3.50.50.60 123 277 1.4E-16 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFULGI_00007420 64085320b5c5ca3a19374d55c1c1cef8 746 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 479 486 5.7E-5 T 01-11-2018 AFULGI_00007420 64085320b5c5ca3a19374d55c1c1cef8 746 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 130 152 5.7E-5 T 01-11-2018 AFULGI_00007420 64085320b5c5ca3a19374d55c1c1cef8 746 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 129 248 3.5E-9 T 01-11-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFULGI_00007420 64085320b5c5ca3a19374d55c1c1cef8 746 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 535 546 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFULGI_00007420 64085320b5c5ca3a19374d55c1c1cef8 746 SUPERFAMILY SSF54862 528 590 4.89E-16 T 01-11-2018 AFULGI_00007420 64085320b5c5ca3a19374d55c1c1cef8 746 Pfam PF13187 4Fe-4S dicluster domain 534 579 7.5E-8 T 01-11-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFULGI_00007420 64085320b5c5ca3a19374d55c1c1cef8 746 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 131 150 4.4E-6 T 01-11-2018 AFULGI_00007420 64085320b5c5ca3a19374d55c1c1cef8 746 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 389 405 4.4E-6 T 01-11-2018 AFULGI_00007420 64085320b5c5ca3a19374d55c1c1cef8 746 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 234 252 4.4E-6 T 01-11-2018 AFULGI_00007420 64085320b5c5ca3a19374d55c1c1cef8 746 SUPERFAMILY SSF51971 128 508 1.11E-29 T 01-11-2018 AFULGI_00019880 d5fcd7cf50b0b64a770c6aaaa48b28cd 642 Gene3D G3DSA:3.40.30.10 2 171 1.3E-74 T 01-11-2018 AFULGI_00019880 d5fcd7cf50b0b64a770c6aaaa48b28cd 642 Pfam PF07221 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) 426 506 0.048 T 01-11-2018 AFULGI_00019880 d5fcd7cf50b0b64a770c6aaaa48b28cd 642 Pfam PF07221 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) 205 315 0.069 T 01-11-2018 AFULGI_00019880 d5fcd7cf50b0b64a770c6aaaa48b28cd 642 SUPERFAMILY SSF52833 3 129 5.3E-36 T 01-11-2018 IPR036249 Thioredoxin-like superfamily AFULGI_00019880 d5fcd7cf50b0b64a770c6aaaa48b28cd 642 PIRSF PIRSF006402 1 620 7.1E-232 T 01-11-2018 IPR024705 Spermatogenesis-associated protein 20 AFULGI_00019880 d5fcd7cf50b0b64a770c6aaaa48b28cd 642 Pfam PF03190 Protein of unknown function, DUF255 3 163 2.2E-75 T 01-11-2018 IPR004879 Domain of unknown function DUF255 AFULGI_00019880 d5fcd7cf50b0b64a770c6aaaa48b28cd 642 SUPERFAMILY SSF48208 187 525 1.13E-59 T 01-11-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 AFULGI_00019880 d5fcd7cf50b0b64a770c6aaaa48b28cd 642 Gene3D G3DSA:1.50.10.20 398 514 2.5E-6 T 01-11-2018 AFULGI_00019880 d5fcd7cf50b0b64a770c6aaaa48b28cd 642 Gene3D G3DSA:1.50.10.10 233 327 8.0E-6 T 01-11-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 AFULGI_00004320 d3901c5ba73d643b683c7f3885b3c3b7 328 Pfam PF06858 Nucleolar GTP-binding protein 1 (NOG1) 221 276 2.0E-23 T 01-11-2018 IPR010674 Nucleolar GTP-binding protein 1, Rossman-fold domain GO:0005525 AFULGI_00004320 d3901c5ba73d643b683c7f3885b3c3b7 328 Gene3D G3DSA:1.20.120.1190 1 148 1.1E-37 T 01-11-2018 AFULGI_00004320 d3901c5ba73d643b683c7f3885b3c3b7 328 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 155 297 4.7E-13 T 01-11-2018 IPR005225 Small GTP-binding protein domain GO:0005525 AFULGI_00004320 d3901c5ba73d643b683c7f3885b3c3b7 328 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 204 219 3.8E-12 T 01-11-2018 IPR006073 GTP binding domain GO:0005525 AFULGI_00004320 d3901c5ba73d643b683c7f3885b3c3b7 328 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 177 195 3.8E-12 T 01-11-2018 IPR006073 GTP binding domain GO:0005525 AFULGI_00004320 d3901c5ba73d643b683c7f3885b3c3b7 328 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 156 176 3.8E-12 T 01-11-2018 IPR006073 GTP binding domain GO:0005525 AFULGI_00004320 d3901c5ba73d643b683c7f3885b3c3b7 328 Gene3D G3DSA:3.40.50.300 149 317 4.1E-46 T 01-11-2018 AFULGI_00004320 d3901c5ba73d643b683c7f3885b3c3b7 328 SUPERFAMILY SSF52540 147 307 1.99E-36 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00017310 8002143a55b41c07e189414f2b46661c 130 Gene3D G3DSA:3.40.50.1010 1 129 1.2E-28 T 01-11-2018 AFULGI_00017310 8002143a55b41c07e189414f2b46661c 130 Pfam PF01850 PIN domain 3 121 1.6E-19 T 01-11-2018 IPR002716 PIN domain AFULGI_00017310 8002143a55b41c07e189414f2b46661c 130 SUPERFAMILY SSF88723 1 126 7.57E-30 T 01-11-2018 IPR029060 PIN-like domain superfamily AFULGI_00012630 ae8973bef5d075eaebe5bf0d35448c2b 339 Gene3D G3DSA:1.20.1690.10 195 297 8.6E-87 T 01-11-2018 IPR035067 V-type ATPase subunit c Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 AFULGI_00012630 ae8973bef5d075eaebe5bf0d35448c2b 339 Hamap MF_00314 V-type ATP synthase subunit C [atpC]. 6 338 27.323 T 01-11-2018 IPR014272 ATPase, V0 complex, c subunit GO:0033179|GO:0046961 AFULGI_00012630 ae8973bef5d075eaebe5bf0d35448c2b 339 TIGRFAM TIGR02923 AhaC: ATP synthase A1, C subunit 7 337 3.1E-140 T 01-11-2018 IPR014272 ATPase, V0 complex, c subunit GO:0033179|GO:0046961 AFULGI_00012630 ae8973bef5d075eaebe5bf0d35448c2b 339 SUPERFAMILY SSF103486 10 338 2.88E-78 T 01-11-2018 IPR036079 V-type ATP synthase subunit C-like Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 AFULGI_00012630 ae8973bef5d075eaebe5bf0d35448c2b 339 Gene3D G3DSA:1.20.1690.10 88 186 8.6E-87 T 01-11-2018 IPR035067 V-type ATPase subunit c Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 AFULGI_00012630 ae8973bef5d075eaebe5bf0d35448c2b 339 Gene3D G3DSA:1.10.132.50 10 331 8.6E-87 T 01-11-2018 AFULGI_00012630 ae8973bef5d075eaebe5bf0d35448c2b 339 Pfam PF01992 ATP synthase (C/AC39) subunit 13 334 1.4E-68 T 01-11-2018 IPR002843 ATPase, V0 complex, c/d subunit Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 AFULGI_00017470 8020ff5b090ed6825049dbb0efad2d50 137 Hamap MF_01222 Protein archease. 1 137 40.494 T 01-11-2018 IPR022952 Archease, archaea AFULGI_00017470 8020ff5b090ed6825049dbb0efad2d50 137 Gene3D G3DSA:3.55.10.10 1 137 1.9E-39 T 01-11-2018 IPR036820 Archease domain superfamily Reactome: R-HSA-6784531 AFULGI_00017470 8020ff5b090ed6825049dbb0efad2d50 137 SUPERFAMILY SSF69819 1 137 6.54E-40 T 01-11-2018 IPR036820 Archease domain superfamily Reactome: R-HSA-6784531 AFULGI_00017470 8020ff5b090ed6825049dbb0efad2d50 137 Pfam PF01951 Archease protein family (MTH1598/TM1083) 3 137 8.4E-39 T 01-11-2018 IPR023572 Archease domain Reactome: R-HSA-6784531 AFULGI_00017470 8020ff5b090ed6825049dbb0efad2d50 137 ProDom PD012969 UPF0211 RIKEN CDNA ENRICHED MALE FULL-LENGTH LIBRARY ZBTB8OS ADULT C43H8.1 7 136 2.0E-43 T 01-11-2018 IPR023572 Archease domain Reactome: R-HSA-6784531 AFULGI_00006470 214214ecdd64a6b15f971fefbc5eff76 97 Gene3D G3DSA:3.30.70.930 1 96 3.8E-26 T 01-11-2018 IPR029756 MTH1187/YkoF-like AFULGI_00006470 214214ecdd64a6b15f971fefbc5eff76 97 TIGRFAM TIGR00106 TIGR00106: uncharacterized protein, MTH1187 family 1 96 6.9E-35 T 01-11-2018 IPR002767 Thiamine-binding protein AFULGI_00006470 214214ecdd64a6b15f971fefbc5eff76 97 Pfam PF01910 Thiamine-binding protein 3 93 2.5E-26 T 01-11-2018 IPR002767 Thiamine-binding protein AFULGI_00006470 214214ecdd64a6b15f971fefbc5eff76 97 SUPERFAMILY SSF89957 1 96 2.75E-25 T 01-11-2018 IPR029756 MTH1187/YkoF-like AFULGI_00020250 3fd432ef9f8facd5917133074adc99e4 531 SUPERFAMILY SSF81301 433 498 6.54E-10 T 01-11-2018 AFULGI_00020250 3fd432ef9f8facd5917133074adc99e4 531 PIRSF PIRSF006060 2 433 1.3E-51 T 01-11-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 AFULGI_00020250 3fd432ef9f8facd5917133074adc99e4 531 Gene3D G3DSA:1.20.1740.10 2 429 6.4E-91 T 01-11-2018 AFULGI_00020250 3fd432ef9f8facd5917133074adc99e4 531 Gene3D G3DSA:3.30.460.10 430 527 3.3E-8 T 01-11-2018 AFULGI_00020250 3fd432ef9f8facd5917133074adc99e4 531 Pfam PF13520 Amino acid permease 5 382 4.4E-31 T 01-11-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 AFULGI_00020250 3fd432ef9f8facd5917133074adc99e4 531 Pfam PF01909 Nucleotidyltransferase domain 444 529 2.5E-12 T 01-11-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 AFULGI_00009680 edb61f6121f7540ec3ca93829f4e57f6 530 Pfam PF13188 PAS domain 198 259 8.7E-8 T 01-11-2018 IPR000014 PAS domain AFULGI_00009680 edb61f6121f7540ec3ca93829f4e57f6 530 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 194 248 1.4E-11 T 01-11-2018 IPR000014 PAS domain AFULGI_00009680 edb61f6121f7540ec3ca93829f4e57f6 530 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 87 191 2.1E-9 T 01-11-2018 IPR000014 PAS domain AFULGI_00009680 edb61f6121f7540ec3ca93829f4e57f6 530 SUPERFAMILY SSF55785 96 192 2.66E-9 T 01-11-2018 IPR035965 PAS domain superfamily AFULGI_00009680 edb61f6121f7540ec3ca93829f4e57f6 530 SMART SM00091 197 262 2.5E-4 T 01-11-2018 IPR000014 PAS domain AFULGI_00009680 edb61f6121f7540ec3ca93829f4e57f6 530 SMART SM00091 74 143 160.0 T 01-11-2018 IPR000014 PAS domain AFULGI_00009680 edb61f6121f7540ec3ca93829f4e57f6 530 Gene3D G3DSA:3.30.450.20 74 196 5.0E-13 T 01-11-2018 AFULGI_00009680 edb61f6121f7540ec3ca93829f4e57f6 530 SUPERFAMILY SSF55781 284 435 1.14E-9 T 01-11-2018 AFULGI_00009680 edb61f6121f7540ec3ca93829f4e57f6 530 Gene3D G3DSA:3.30.450.20 197 297 5.0E-13 T 01-11-2018 AFULGI_00009680 edb61f6121f7540ec3ca93829f4e57f6 530 Pfam PF08448 PAS fold 92 187 4.6E-8 T 01-11-2018 IPR013656 PAS fold-4 AFULGI_00009680 edb61f6121f7540ec3ca93829f4e57f6 530 SUPERFAMILY SSF55785 181 278 4.19E-17 T 01-11-2018 IPR035965 PAS domain superfamily AFULGI_00009680 edb61f6121f7540ec3ca93829f4e57f6 530 Pfam PF01590 GAF domain 329 435 4.5E-5 T 01-11-2018 IPR003018 GAF domain GO:0005515 AFULGI_00009680 edb61f6121f7540ec3ca93829f4e57f6 530 Gene3D G3DSA:3.30.450.40 298 442 7.8E-6 T 01-11-2018 IPR029016 GAF-like domain superfamily AFULGI_00017620 470589b1e933e844e280e305eb211436 552 ProSitePatterns PS00455 Putative AMP-binding domain signature. 198 209 - T 01-11-2018 IPR020845 AMP-binding, conserved site AFULGI_00017620 470589b1e933e844e280e305eb211436 552 SUPERFAMILY SSF56801 8 545 7.46E-161 T 01-11-2018 AFULGI_00017620 470589b1e933e844e280e305eb211436 552 Pfam PF00501 AMP-binding enzyme 28 447 1.5E-114 T 01-11-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFULGI_00017620 470589b1e933e844e280e305eb211436 552 Gene3D G3DSA:3.30.300.310 443 549 4.9E-29 T 01-11-2018 AFULGI_00017620 470589b1e933e844e280e305eb211436 552 Pfam PF13193 AMP-binding enzyme C-terminal domain 456 533 2.1E-19 T 01-11-2018 IPR025110 AMP-binding enzyme, C-terminal domain AFULGI_00017620 470589b1e933e844e280e305eb211436 552 Gene3D G3DSA:3.40.50.12780 13 442 1.9E-125 T 01-11-2018 AFULGI_00020320 83e4f7d2655bc85229a6dc15ce5de463 437 Pfam PF01957 NfeD-like C-terminal, partner-binding 283 420 1.9E-34 T 01-11-2018 IPR002810 NfeD-like, C-terminal domain AFULGI_00020320 83e4f7d2655bc85229a6dc15ce5de463 437 Gene3D G3DSA:2.40.50.140 354 428 5.5E-16 T 01-11-2018 AFULGI_00020320 83e4f7d2655bc85229a6dc15ce5de463 437 SUPERFAMILY SSF141322 359 422 1.44E-17 T 01-11-2018 AFULGI_00020320 83e4f7d2655bc85229a6dc15ce5de463 437 Gene3D G3DSA:3.90.226.10 18 233 8.1E-47 T 01-11-2018 AFULGI_00020320 83e4f7d2655bc85229a6dc15ce5de463 437 SUPERFAMILY SSF52096 19 185 1.53E-26 T 01-11-2018 IPR029045 ClpP/crotonase-like domain superfamily AFULGI_00020320 83e4f7d2655bc85229a6dc15ce5de463 437 Pfam PF00574 Clp protease 56 185 1.1E-4 T 01-11-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA AFULGI_00008040 9a99de5fc1673934e87287753af3f5cc 443 TIGRFAM TIGR01466 cobJ_cbiH: precorrin-3B C17-methyltransferase 7 240 2.9E-98 T 01-11-2018 IPR006363 Precorrin-3B C17-methyltransferase domain GO:0008168|GO:0009236 AFULGI_00008040 9a99de5fc1673934e87287753af3f5cc 443 PIRSF PIRSF004874 1 443 2.8E-240 T 01-11-2018 IPR014422 Cobalamin (vitamin B12) biosynthesis, bifunctional CbiH/CbiC GO:0009236 KEGG: 00860+5.4.99.60|MetaCyc: PWY-7377 AFULGI_00008040 9a99de5fc1673934e87287753af3f5cc 443 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 6 211 5.6E-36 T 01-11-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 AFULGI_00008040 9a99de5fc1673934e87287753af3f5cc 443 SUPERFAMILY SSF53790 4 251 2.62E-51 T 01-11-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 AFULGI_00008040 9a99de5fc1673934e87287753af3f5cc 443 Gene3D G3DSA:3.30.950.10 115 242 8.4E-44 T 01-11-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 AFULGI_00008040 9a99de5fc1673934e87287753af3f5cc 443 Gene3D G3DSA:3.40.1010.10 2 114 8.6E-33 T 01-11-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 AFULGI_00008040 9a99de5fc1673934e87287753af3f5cc 443 Gene3D G3DSA:3.40.50.10230 258 443 5.1E-41 T 01-11-2018 IPR036588 Precorrin-8X methylmutase CobH/CbiC superfamily GO:0009236|GO:0016993 AFULGI_00008040 9a99de5fc1673934e87287753af3f5cc 443 SUPERFAMILY SSF63965 257 438 4.45E-46 T 01-11-2018 IPR036588 Precorrin-8X methylmutase CobH/CbiC superfamily GO:0009236|GO:0016993 AFULGI_00008040 9a99de5fc1673934e87287753af3f5cc 443 Pfam PF02570 Precorrin-8X methylmutase 266 437 1.3E-40 T 01-11-2018 IPR003722 Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC GO:0009236|GO:0016993 AFULGI_00005910 78de99596c47de8bcfb2e8b25f18fc82 94 Pfam PF00085 Thioredoxin 3 87 2.6E-24 T 01-11-2018 IPR013766 Thioredoxin domain GO:0045454 AFULGI_00005910 78de99596c47de8bcfb2e8b25f18fc82 94 SUPERFAMILY SSF52833 4 91 1.74E-31 T 01-11-2018 IPR036249 Thioredoxin-like superfamily AFULGI_00005910 78de99596c47de8bcfb2e8b25f18fc82 94 TIGRFAM TIGR01068 thioredoxin: thioredoxin 3 89 3.3E-29 T 01-11-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 AFULGI_00005910 78de99596c47de8bcfb2e8b25f18fc82 94 Gene3D G3DSA:3.40.30.10 1 92 1.3E-29 T 01-11-2018 AFULGI_00005910 78de99596c47de8bcfb2e8b25f18fc82 94 ProSitePatterns PS00194 Thioredoxin family active site. 8 26 - T 01-11-2018 IPR017937 Thioredoxin, conserved site GO:0045454 AFULGI_00005910 78de99596c47de8bcfb2e8b25f18fc82 94 PIRSF PIRSF000077 1 90 1.3E-27 T 01-11-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 AFULGI_00005910 78de99596c47de8bcfb2e8b25f18fc82 94 PRINTS PR00421 Thioredoxin family signature 7 15 1.8E-8 T 01-11-2018 AFULGI_00005910 78de99596c47de8bcfb2e8b25f18fc82 94 PRINTS PR00421 Thioredoxin family signature 54 65 1.8E-8 T 01-11-2018 AFULGI_00005910 78de99596c47de8bcfb2e8b25f18fc82 94 PRINTS PR00421 Thioredoxin family signature 15 24 1.8E-8 T 01-11-2018 AFULGI_00010900 d691fae33252994a38abc8ccc3e006f4 569 SUPERFAMILY SSF52540 169 498 5.8E-59 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00010900 d691fae33252994a38abc8ccc3e006f4 569 Pfam PF00437 Type II/IV secretion system protein 193 436 1.7E-48 T 01-11-2018 IPR001482 Type II/IV secretion system protein AFULGI_00010900 d691fae33252994a38abc8ccc3e006f4 569 Gene3D G3DSA:3.40.50.300 288 569 8.6E-105 T 01-11-2018 AFULGI_00010900 d691fae33252994a38abc8ccc3e006f4 569 Gene3D G3DSA:3.30.450.380 62 286 3.5E-70 T 01-11-2018 AFULGI_00020400 65c432dfc3b55343fa12e06dddad2a2e 203 SUPERFAMILY SSF53271 3 134 8.7E-21 T 01-11-2018 IPR029057 Phosphoribosyltransferase-like AFULGI_00020400 65c432dfc3b55343fa12e06dddad2a2e 203 Gene3D G3DSA:3.40.50.2020 2 156 2.5E-25 T 01-11-2018 AFULGI_00024830 85fcb93e4a8d75a411bd0b32e69f899e 160 Gene3D G3DSA:3.30.428.10 1 160 2.8E-53 T 01-11-2018 IPR036265 HIT-like superfamily AFULGI_00024830 85fcb93e4a8d75a411bd0b32e69f899e 160 SUPERFAMILY SSF54197 1 150 7.58E-42 T 01-11-2018 IPR036265 HIT-like superfamily AFULGI_00024830 85fcb93e4a8d75a411bd0b32e69f899e 160 Pfam PF01230 HIT domain 34 125 2.4E-15 T 01-11-2018 IPR001310 Histidine triad (HIT) protein AFULGI_00005340 febd9aff9a024317a341fbd47cca79fb 259 SUPERFAMILY SSF159659 11 248 1.83E-51 T 01-11-2018 AFULGI_00005340 febd9aff9a024317a341fbd47cca79fb 259 Pfam PF09754 PAC2 family 23 237 2.1E-53 T 01-11-2018 IPR019151 Proteasome assembly chaperone 2 AFULGI_00005340 febd9aff9a024317a341fbd47cca79fb 259 TIGRFAM TIGR00162 TIGR00162: TIGR00162 family protein 1 259 1.0E-142 T 01-11-2018 IPR004426 Conserved hypothetical protein CHP00062 AFULGI_00005340 febd9aff9a024317a341fbd47cca79fb 259 Gene3D G3DSA:3.40.50.10900 7 257 2.1E-69 T 01-11-2018 IPR038389 Proteasome assembly chaperone 2 superfamily AFULGI_00025550 d023866d888b1abbe13acb923c9da48f 196 Gene3D G3DSA:1.20.58.2140 1 196 1.7E-76 T 01-11-2018 AFULGI_00025550 d023866d888b1abbe13acb923c9da48f 196 SUPERFAMILY SSF74784 4 179 2.35E-25 T 01-11-2018 IPR036081 Translin superfamily GO:0043565 Reactome: R-HSA-426486 AFULGI_00025550 d023866d888b1abbe13acb923c9da48f 196 Pfam PF01997 Translin family 17 175 1.4E-9 T 01-11-2018 IPR002848 Translin family GO:0043565 Reactome: R-HSA-426486 AFULGI_00016010 12ddc31af295d612863752be0e237756 374 Gene3D G3DSA:2.60.40.10 282 367 4.1E-7 T 01-11-2018 IPR013783 Immunoglobulin-like fold AFULGI_00016010 12ddc31af295d612863752be0e237756 374 SUPERFAMILY SSF49373 285 364 1.07E-7 T 01-11-2018 IPR008964 Invasin/intimin cell-adhesion fragments AFULGI_00011210 a57ec7d32c19c8c7e039bf17452b249e 373 Gene3D G3DSA:3.40.50.720 1 187 3.4E-73 T 01-11-2018 AFULGI_00011210 a57ec7d32c19c8c7e039bf17452b249e 373 Gene3D G3DSA:1.10.1040.10 296 373 2.8E-26 T 01-11-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AFULGI_00011210 a57ec7d32c19c8c7e039bf17452b249e 373 SUPERFAMILY SSF48179 301 371 2.98E-13 T 01-11-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AFULGI_00011210 a57ec7d32c19c8c7e039bf17452b249e 373 PIRSF PIRSF000105 298 371 1.8E-6 T 01-11-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 AFULGI_00011210 a57ec7d32c19c8c7e039bf17452b249e 373 PIRSF PIRSF000105 1 299 1.0E-90 T 01-11-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 AFULGI_00011210 a57ec7d32c19c8c7e039bf17452b249e 373 SUPERFAMILY SSF48179 185 285 1.62E-29 T 01-11-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AFULGI_00011210 a57ec7d32c19c8c7e039bf17452b249e 373 SUPERFAMILY SSF51735 1 182 6.77E-63 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily AFULGI_00011210 a57ec7d32c19c8c7e039bf17452b249e 373 Gene3D G3DSA:1.10.1040.10 188 295 1.3E-29 T 01-11-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AFULGI_00011210 a57ec7d32c19c8c7e039bf17452b249e 373 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 186 280 7.9E-29 T 01-11-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 AFULGI_00011210 a57ec7d32c19c8c7e039bf17452b249e 373 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 303 371 4.1E-11 T 01-11-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 AFULGI_00011210 a57ec7d32c19c8c7e039bf17452b249e 373 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 5 183 6.4E-69 T 01-11-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 AFULGI_00014780 16f5a7abba9202588c88ce6c4fb29d48 740 Gene3D G3DSA:3.30.110.120 240 353 5.3E-125 T 01-11-2018 AFULGI_00014780 16f5a7abba9202588c88ce6c4fb29d48 740 SUPERFAMILY SSF55821 169 375 3.97E-40 T 01-11-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily AFULGI_00014780 16f5a7abba9202588c88ce6c4fb29d48 740 SUPERFAMILY SSF54975 3 84 1.88E-20 T 01-11-2018 IPR036046 Acylphosphatase-like domain superfamily KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 AFULGI_00014780 16f5a7abba9202588c88ce6c4fb29d48 740 TIGRFAM TIGR00143 hypF: carbamoyltransferase HypF 4 735 0.0 T 01-11-2018 IPR004421 Carbamoyltransferase, HypF-type GO:0016743|GO:0046872|GO:0046944 AFULGI_00014780 16f5a7abba9202588c88ce6c4fb29d48 740 Gene3D G3DSA:3.90.870.50 4 344 5.3E-125 T 01-11-2018 AFULGI_00014780 16f5a7abba9202588c88ce6c4fb29d48 740 SUPERFAMILY SSF53067 400 721 8.42E-6 T 01-11-2018 AFULGI_00014780 16f5a7abba9202588c88ce6c4fb29d48 740 ProSitePatterns PS00150 Acylphosphatase signature 1. 6 16 - T 01-11-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 AFULGI_00014780 16f5a7abba9202588c88ce6c4fb29d48 740 Pfam PF01300 Telomere recombination 198 365 3.5E-44 T 01-11-2018 IPR006070 YrdC-like domain GO:0003725 AFULGI_00014780 16f5a7abba9202588c88ce6c4fb29d48 740 Gene3D G3DSA:3.30.420.350 469 721 9.8E-87 T 01-11-2018 AFULGI_00014780 16f5a7abba9202588c88ce6c4fb29d48 740 Pfam PF07503 HypF finger 101 133 1.8E-15 T 01-11-2018 IPR011125 Zinc finger, HypF-type GO:0008270 AFULGI_00014780 16f5a7abba9202588c88ce6c4fb29d48 740 Pfam PF07503 HypF finger 151 183 7.5E-15 T 01-11-2018 IPR011125 Zinc finger, HypF-type GO:0008270 AFULGI_00014780 16f5a7abba9202588c88ce6c4fb29d48 740 Pfam PF00708 Acylphosphatase 3 83 2.0E-19 T 01-11-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 AFULGI_00014780 16f5a7abba9202588c88ce6c4fb29d48 740 Gene3D G3DSA:3.30.420.360 365 733 9.8E-87 T 01-11-2018 AFULGI_00014780 16f5a7abba9202588c88ce6c4fb29d48 740 PIRSF PIRSF006256 1 740 1.8E-254 T 01-11-2018 IPR004421 Carbamoyltransferase, HypF-type GO:0016743|GO:0046872|GO:0046944 AFULGI_00014710 2612b651f0d9542186e5e821545cabbf 201 Gene3D G3DSA:1.20.58.220 3 198 6.2E-30 T 01-11-2018 IPR038078 PhoU-like domain superfamily AFULGI_00014710 2612b651f0d9542186e5e821545cabbf 201 Pfam PF01895 PhoU domain 15 99 1.0E-11 T 01-11-2018 IPR026022 PhoU domain AFULGI_00014710 2612b651f0d9542186e5e821545cabbf 201 SUPERFAMILY SSF109755 2 198 2.41E-30 T 01-11-2018 AFULGI_00013640 7c322e731b19665da39daff4c5dd485d 231 Gene3D G3DSA:3.60.15.10 1 229 5.0E-79 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFULGI_00013640 7c322e731b19665da39daff4c5dd485d 231 Pfam PF13483 Beta-lactamase superfamily domain 2 191 5.5E-30 T 01-11-2018 AFULGI_00013640 7c322e731b19665da39daff4c5dd485d 231 SUPERFAMILY SSF56281 1 229 1.83E-38 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFULGI_00013640 7c322e731b19665da39daff4c5dd485d 231 Hamap MF_00457 UPF0173 metal-dependent hydrolase . 1 229 40.722 T 01-11-2018 IPR022877 Protein of unknown funcion UPF0173 AFULGI_00013640 7c322e731b19665da39daff4c5dd485d 231 SMART SM00849 7 191 2.2E-11 T 01-11-2018 IPR001279 Metallo-beta-lactamase AFULGI_00024160 16c0e20973f62827bbe73cf591cd00a2 352 Pfam PF01926 50S ribosome-binding GTPase 63 171 9.2E-23 T 01-11-2018 IPR006073 GTP binding domain GO:0005525 AFULGI_00024160 16c0e20973f62827bbe73cf591cd00a2 352 Pfam PF02824 TGS domain 279 351 1.9E-24 T 01-11-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 AFULGI_00024160 16c0e20973f62827bbe73cf591cd00a2 352 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 63 175 2.7E-18 T 01-11-2018 IPR005225 Small GTP-binding protein domain GO:0005525 AFULGI_00024160 16c0e20973f62827bbe73cf591cd00a2 352 SUPERFAMILY SSF81271 273 351 2.62E-19 T 01-11-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 AFULGI_00024160 16c0e20973f62827bbe73cf591cd00a2 352 SUPERFAMILY SSF52540 63 292 1.89E-54 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00024160 16c0e20973f62827bbe73cf591cd00a2 352 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 84 102 5.1E-31 T 01-11-2018 IPR006073 GTP binding domain GO:0005525 AFULGI_00024160 16c0e20973f62827bbe73cf591cd00a2 352 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 128 146 5.1E-31 T 01-11-2018 IPR006073 GTP binding domain GO:0005525 AFULGI_00024160 16c0e20973f62827bbe73cf591cd00a2 352 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 63 83 5.1E-31 T 01-11-2018 IPR006073 GTP binding domain GO:0005525 AFULGI_00024160 16c0e20973f62827bbe73cf591cd00a2 352 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 111 126 5.1E-31 T 01-11-2018 IPR006073 GTP binding domain GO:0005525 AFULGI_00024160 16c0e20973f62827bbe73cf591cd00a2 352 Gene3D G3DSA:3.10.20.30 277 352 2.4E-33 T 01-11-2018 IPR012675 Beta-grasp domain superfamily AFULGI_00024160 16c0e20973f62827bbe73cf591cd00a2 352 ProSitePatterns PS00905 GTP1/OBG family signature. 113 126 - T 01-11-2018 IPR006074 GTP1/OBG, conserved site GO:0005525 AFULGI_00024160 16c0e20973f62827bbe73cf591cd00a2 352 Pfam PF16897 C-terminal region of MMR_HSR1 domain 181 277 5.6E-31 T 01-11-2018 IPR031662 GTP binding protein, second domain AFULGI_00013400 54a028a64f231388baeaba085a8b100d 289 SUPERFAMILY SSF54782 212 285 1.57E-11 T 01-11-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AFULGI_00013400 54a028a64f231388baeaba085a8b100d 289 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 3 207 2.2E-70 T 01-11-2018 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AFULGI_00013400 54a028a64f231388baeaba085a8b100d 289 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 223 239 - T 01-11-2018 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AFULGI_00013400 54a028a64f231388baeaba085a8b100d 289 Gene3D G3DSA:3.40.190.10 97 197 9.6E-74 T 01-11-2018 AFULGI_00013400 54a028a64f231388baeaba085a8b100d 289 PIRSF PIRSF001438 1 288 1.4E-99 T 01-11-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AFULGI_00013400 54a028a64f231388baeaba085a8b100d 289 Gene3D G3DSA:3.30.160.40 213 289 3.4E-7 T 01-11-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AFULGI_00013400 54a028a64f231388baeaba085a8b100d 289 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 217 287 7.9E-18 T 01-11-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AFULGI_00013400 54a028a64f231388baeaba085a8b100d 289 SUPERFAMILY SSF53850 1 211 1.43E-70 T 01-11-2018 AFULGI_00013400 54a028a64f231388baeaba085a8b100d 289 Gene3D G3DSA:3.40.190.10 4 205 9.6E-74 T 01-11-2018 AFULGI_00013400 54a028a64f231388baeaba085a8b100d 289 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 3 285 1.1E-93 T 01-11-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AFULGI_00013400 54a028a64f231388baeaba085a8b100d 289 PRINTS PR00151 Porphobilinogen deaminase signature 222 239 9.7E-36 T 01-11-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AFULGI_00013400 54a028a64f231388baeaba085a8b100d 289 PRINTS PR00151 Porphobilinogen deaminase signature 137 154 9.7E-36 T 01-11-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AFULGI_00013400 54a028a64f231388baeaba085a8b100d 289 PRINTS PR00151 Porphobilinogen deaminase signature 118 135 9.7E-36 T 01-11-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AFULGI_00013400 54a028a64f231388baeaba085a8b100d 289 PRINTS PR00151 Porphobilinogen deaminase signature 70 89 9.7E-36 T 01-11-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AFULGI_00013400 54a028a64f231388baeaba085a8b100d 289 PRINTS PR00151 Porphobilinogen deaminase signature 39 59 9.7E-36 T 01-11-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AFULGI_00013400 54a028a64f231388baeaba085a8b100d 289 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 2 289 35.515 T 01-11-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AFULGI_00024630 ddcf155dfa179fd7091be6d4356c09a6 109 Pfam PF03100 CcmE 7 107 1.4E-10 T 01-11-2018 IPR004329 CcmE/CycJ protein GO:0005886|GO:0017003|GO:0017004|GO:0020037 AFULGI_00024630 ddcf155dfa179fd7091be6d4356c09a6 109 Gene3D G3DSA:2.40.50.140 22 108 2.0E-8 T 01-11-2018 AFULGI_00024630 ddcf155dfa179fd7091be6d4356c09a6 109 SUPERFAMILY SSF82093 22 107 1.57E-10 T 01-11-2018 IPR036127 CcmE-like superfamily GO:0005886|GO:0017003|GO:0017004 AFULGI_00012660 1a18d3a0715e9365d4cbb337c5acf389 472 SUPERFAMILY SSF52540 79 353 1.02E-84 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00012660 1a18d3a0715e9365d4cbb337c5acf389 472 SUPERFAMILY SSF50615 2 77 4.97E-7 T 01-11-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 AFULGI_00012660 1a18d3a0715e9365d4cbb337c5acf389 472 PIRSF PIRSF039114 1 464 2.7E-254 T 01-11-2018 IPR022879 V-type ATP synthase regulatory subunit B/beta Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 AFULGI_00012660 1a18d3a0715e9365d4cbb337c5acf389 472 Hamap MF_00310 V-type ATP synthase beta chain [atpB]. 3 458 61.876 T 01-11-2018 IPR022879 V-type ATP synthase regulatory subunit B/beta Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 AFULGI_00012660 1a18d3a0715e9365d4cbb337c5acf389 472 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 340 349 - T 01-11-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 AFULGI_00012660 1a18d3a0715e9365d4cbb337c5acf389 472 TIGRFAM TIGR01041 ATP_syn_B_arch: ATP synthase archaeal, B subunit 5 460 8.1E-270 T 01-11-2018 IPR005724 ATPase, A1 complex, beta subunit GO:0015986|GO:0033178|GO:0046933 AFULGI_00012660 1a18d3a0715e9365d4cbb337c5acf389 472 SUPERFAMILY SSF47917 360 422 9.94E-9 T 01-11-2018 AFULGI_00012660 1a18d3a0715e9365d4cbb337c5acf389 472 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 131 349 4.4E-67 T 01-11-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 AFULGI_00012660 1a18d3a0715e9365d4cbb337c5acf389 472 Gene3D G3DSA:3.40.50.12240 14 461 3.1E-186 T 01-11-2018 AFULGI_00012660 1a18d3a0715e9365d4cbb337c5acf389 472 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 9 74 1.7E-15 T 01-11-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 AFULGI_00004620 0341da7ec389b39f94d481ec400c8655 151 SUPERFAMILY SSF48695 3 92 1.51E-15 T 01-11-2018 IPR036280 Multiheme cytochrome superfamily AFULGI_00004620 0341da7ec389b39f94d481ec400c8655 151 Pfam PF09719 Putative redox-active protein (C_GCAxxG_C_C) 20 142 7.5E-18 T 01-11-2018 IPR010181 CGCAxxGCC motif AFULGI_00004620 0341da7ec389b39f94d481ec400c8655 151 TIGRFAM TIGR01909 C_GCAxxG_C_C: C_GCAxxG_C_C family protein 19 146 3.0E-47 T 01-11-2018 IPR010181 CGCAxxGCC motif AFULGI_00001590 c873fff675f38ddae1ad73606e7988d9 397 Gene3D G3DSA:2.170.190.11 51 140 3.5E-92 T 01-11-2018 AFULGI_00001590 c873fff675f38ddae1ad73606e7988d9 397 Pfam PF00994 Probable molybdopterin binding domain 179 299 3.0E-27 T 01-11-2018 IPR001453 MoaB/Mog domain AFULGI_00001590 c873fff675f38ddae1ad73606e7988d9 397 Pfam PF03453 MoeA N-terminal region (domain I and II) 20 166 4.5E-38 T 01-11-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AFULGI_00001590 c873fff675f38ddae1ad73606e7988d9 397 Gene3D G3DSA:3.40.980.10 26 302 3.5E-92 T 01-11-2018 IPR036425 MoaB/Mog-like domain superfamily AFULGI_00001590 c873fff675f38ddae1ad73606e7988d9 397 Gene3D G3DSA:3.90.105.10 27 173 3.5E-92 T 01-11-2018 AFULGI_00001590 c873fff675f38ddae1ad73606e7988d9 397 ProSitePatterns PS01079 Molybdenum cofactor biosynthesis proteins signature 2. 245 278 - T 01-11-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 AFULGI_00001590 c873fff675f38ddae1ad73606e7988d9 397 SMART SM00852 179 309 3.6E-31 T 01-11-2018 IPR001453 MoaB/Mog domain AFULGI_00001590 c873fff675f38ddae1ad73606e7988d9 397 SUPERFAMILY SSF63882 3 175 6.8E-48 T 01-11-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AFULGI_00001590 c873fff675f38ddae1ad73606e7988d9 397 SUPERFAMILY SSF53218 176 300 9.29E-36 T 01-11-2018 IPR036425 MoaB/Mog-like domain superfamily AFULGI_00001590 c873fff675f38ddae1ad73606e7988d9 397 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 176 300 2.1E-36 T 01-11-2018 IPR001453 MoaB/Mog domain AFULGI_00005430 9094b318ce6edca51458a7687e77373c 319 Gene3D G3DSA:1.10.10.10 254 318 2.9E-7 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00005430 9094b318ce6edca51458a7687e77373c 319 SMART SM00849 23 225 4.9E-40 T 01-11-2018 IPR001279 Metallo-beta-lactamase AFULGI_00005430 9094b318ce6edca51458a7687e77373c 319 SUPERFAMILY SSF56281 3 315 1.23E-61 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFULGI_00005430 9094b318ce6edca51458a7687e77373c 319 Gene3D G3DSA:3.60.15.10 2 253 1.6E-62 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFULGI_00005430 9094b318ce6edca51458a7687e77373c 319 Pfam PF00753 Metallo-beta-lactamase superfamily 22 225 1.5E-24 T 01-11-2018 IPR001279 Metallo-beta-lactamase AFULGI_00013570 7099eff44e35f67bb691ce5e4143737e 259 Pfam PF02195 ParB-like nuclease domain 114 224 3.2E-14 T 01-11-2018 IPR003115 ParB/Sulfiredoxin AFULGI_00013570 7099eff44e35f67bb691ce5e4143737e 259 PIRSF PIRSF004699 1 259 4.4E-125 T 01-11-2018 IPR016427 Uncharacterised conserved protein UCP004699, CBS/ParB-like AFULGI_00013570 7099eff44e35f67bb691ce5e4143737e 259 Gene3D G3DSA:3.10.580.10 1 58 1.5E-16 T 01-11-2018 AFULGI_00013570 7099eff44e35f67bb691ce5e4143737e 259 SMART SM00470 147 229 5.4E-15 T 01-11-2018 IPR003115 ParB/Sulfiredoxin AFULGI_00013570 7099eff44e35f67bb691ce5e4143737e 259 SUPERFAMILY SSF110849 146 227 2.35E-18 T 01-11-2018 IPR036086 ParB/Sulfiredoxin superfamily AFULGI_00013570 7099eff44e35f67bb691ce5e4143737e 259 Gene3D G3DSA:3.10.580.10 59 122 8.0E-15 T 01-11-2018 AFULGI_00013570 7099eff44e35f67bb691ce5e4143737e 259 SMART SM00116 12 60 3.8E-9 T 01-11-2018 IPR000644 CBS domain AFULGI_00013570 7099eff44e35f67bb691ce5e4143737e 259 SMART SM00116 71 119 8.3E-10 T 01-11-2018 IPR000644 CBS domain AFULGI_00013570 7099eff44e35f67bb691ce5e4143737e 259 SUPERFAMILY SSF54631 3 120 1.52E-35 T 01-11-2018 AFULGI_00013570 7099eff44e35f67bb691ce5e4143737e 259 Pfam PF00571 CBS domain 64 117 8.6E-12 T 01-11-2018 IPR000644 CBS domain AFULGI_00013570 7099eff44e35f67bb691ce5e4143737e 259 Pfam PF00571 CBS domain 5 58 2.8E-14 T 01-11-2018 IPR000644 CBS domain AFULGI_00013570 7099eff44e35f67bb691ce5e4143737e 259 Gene3D G3DSA:3.90.1530.10 126 230 1.7E-8 T 01-11-2018 AFULGI_00009650 4761fcf0cc37ffa743bad08c269679cb 192 Hamap MF_02131 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase [mptE]. 1 190 30.785 T 01-11-2018 IPR027510 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, MptE GO:0003848|GO:0005524 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 AFULGI_00009650 4761fcf0cc37ffa743bad08c269679cb 192 Pfam PF01973 Protein of unknown function DUF115 64 168 1.5E-13 T 01-11-2018 IPR002826 6-hydroxymethylpterin diphosphokinase MptE-like AFULGI_00005630 a55eec81d210dd1c482b1bd2000e1edd 267 Pfam PF00899 ThiF family 10 243 6.0E-68 T 01-11-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 AFULGI_00005630 a55eec81d210dd1c482b1bd2000e1edd 267 Gene3D G3DSA:3.40.50.720 2 252 2.8E-86 T 01-11-2018 AFULGI_00005630 a55eec81d210dd1c482b1bd2000e1edd 267 SUPERFAMILY SSF69572 5 247 2.22E-91 T 01-11-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 AFULGI_00015350 6d9fdf15a504fb05640a0a02aa3d763a 880 Pfam PF03699 Uncharacterised protein family (UPF0182) 21 755 1.7E-243 T 01-11-2018 IPR005372 Uncharacterised protein family UPF0182 GO:0016021 AFULGI_00015350 6d9fdf15a504fb05640a0a02aa3d763a 880 Hamap MF_01600 UPF0182 protein . 12 830 18.266 T 01-11-2018 IPR005372 Uncharacterised protein family UPF0182 GO:0016021 AFULGI_00026490 7bda1232f0e66fe66df111d1f2e63aef 562 Gene3D G3DSA:3.40.50.12780 39 454 3.1E-118 T 01-11-2018 AFULGI_00026490 7bda1232f0e66fe66df111d1f2e63aef 562 ProSitePatterns PS00455 Putative AMP-binding domain signature. 215 226 - T 01-11-2018 IPR020845 AMP-binding, conserved site AFULGI_00026490 7bda1232f0e66fe66df111d1f2e63aef 562 Gene3D G3DSA:3.30.300.310 457 561 1.9E-35 T 01-11-2018 AFULGI_00026490 7bda1232f0e66fe66df111d1f2e63aef 562 SUPERFAMILY SSF56801 31 557 3.4E-158 T 01-11-2018 AFULGI_00026490 7bda1232f0e66fe66df111d1f2e63aef 562 Pfam PF00501 AMP-binding enzyme 48 460 1.8E-106 T 01-11-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFULGI_00026490 7bda1232f0e66fe66df111d1f2e63aef 562 Pfam PF13193 AMP-binding enzyme C-terminal domain 470 547 4.7E-22 T 01-11-2018 IPR025110 AMP-binding enzyme, C-terminal domain AFULGI_00014960 c6b584fcccd671adc330dac15e5a3897 122 Pfam PF00072 Response regulator receiver domain 7 114 8.6E-26 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFULGI_00014960 c6b584fcccd671adc330dac15e5a3897 122 SMART SM00448 5 114 1.6E-28 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFULGI_00014960 c6b584fcccd671adc330dac15e5a3897 122 Gene3D G3DSA:3.40.50.2300 1 122 1.7E-35 T 01-11-2018 AFULGI_00014960 c6b584fcccd671adc330dac15e5a3897 122 SUPERFAMILY SSF52172 3 118 3.56E-34 T 01-11-2018 IPR011006 CheY-like superfamily AFULGI_00017930 a1536e37a71e80d0ff94347d43109fbb 290 SUPERFAMILY SSF51735 2 124 5.93E-42 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily AFULGI_00017930 a1536e37a71e80d0ff94347d43109fbb 290 SUPERFAMILY SSF52210 125 288 2.35E-49 T 01-11-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AFULGI_00017930 a1536e37a71e80d0ff94347d43109fbb 290 Hamap MF_01988 Succinate--CoA ligase [ADP-forming] subunit alpha [sucD]. 3 289 42.143 T 01-11-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 AFULGI_00017930 a1536e37a71e80d0ff94347d43109fbb 290 PIRSF PIRSF001553 1 290 4.1E-133 T 01-11-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 AFULGI_00017930 a1536e37a71e80d0ff94347d43109fbb 290 Gene3D G3DSA:3.40.50.261 126 290 3.4E-68 T 01-11-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AFULGI_00017930 a1536e37a71e80d0ff94347d43109fbb 290 Gene3D G3DSA:3.40.50.720 1 125 6.3E-49 T 01-11-2018 AFULGI_00017930 a1536e37a71e80d0ff94347d43109fbb 290 SMART SM00881 6 102 7.8E-33 T 01-11-2018 IPR003781 CoA-binding GO:0048037 AFULGI_00017930 a1536e37a71e80d0ff94347d43109fbb 290 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 5 289 1.8E-133 T 01-11-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 AFULGI_00017930 a1536e37a71e80d0ff94347d43109fbb 290 PRINTS PR01798 Succinyl-CoA synthase signature 210 223 1.1E-37 T 01-11-2018 AFULGI_00017930 a1536e37a71e80d0ff94347d43109fbb 290 PRINTS PR01798 Succinyl-CoA synthase signature 84 101 1.1E-37 T 01-11-2018 AFULGI_00017930 a1536e37a71e80d0ff94347d43109fbb 290 PRINTS PR01798 Succinyl-CoA synthase signature 241 258 1.1E-37 T 01-11-2018 AFULGI_00017930 a1536e37a71e80d0ff94347d43109fbb 290 PRINTS PR01798 Succinyl-CoA synthase signature 179 197 1.1E-37 T 01-11-2018 AFULGI_00017930 a1536e37a71e80d0ff94347d43109fbb 290 Pfam PF00549 CoA-ligase 153 272 3.2E-18 T 01-11-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AFULGI_00017930 a1536e37a71e80d0ff94347d43109fbb 290 Pfam PF02629 CoA binding domain 8 101 5.4E-31 T 01-11-2018 IPR003781 CoA-binding GO:0048037 AFULGI_00017930 a1536e37a71e80d0ff94347d43109fbb 290 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 237 250 - T 01-11-2018 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site AFULGI_00017930 a1536e37a71e80d0ff94347d43109fbb 290 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 154 183 - T 01-11-2018 IPR033847 ATP-citrate lyase/succinyl-CoA ligase, conserved site AFULGI_00004860 1815ded5b5c553963e285815ff68f29b 254 SMART SM00849 35 217 4.4E-18 T 01-11-2018 IPR001279 Metallo-beta-lactamase AFULGI_00004860 1815ded5b5c553963e285815ff68f29b 254 Gene3D G3DSA:3.60.15.10 1 242 4.2E-55 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFULGI_00004860 1815ded5b5c553963e285815ff68f29b 254 Pfam PF12706 Beta-lactamase superfamily domain 47 217 3.3E-28 T 01-11-2018 IPR001279 Metallo-beta-lactamase AFULGI_00004860 1815ded5b5c553963e285815ff68f29b 254 SUPERFAMILY SSF56281 1 229 1.04E-48 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFULGI_00019860 dcdfbb0d1ed22c5bd916309378faae48 330 Pfam PF12698 ABC-2 family transporter protein 20 284 4.8E-13 T 01-11-2018 AFULGI_00016690 0b5be8c6a852c9b7fc4391a23db8ab5c 883 Gene3D G3DSA:3.40.50.2300 506 643 1.8E-5 T 01-11-2018 AFULGI_00016690 0b5be8c6a852c9b7fc4391a23db8ab5c 883 SMART SM00950 584 874 2.4E-7 T 01-11-2018 IPR003165 Piwi domain GO:0003676 AFULGI_00016690 0b5be8c6a852c9b7fc4391a23db8ab5c 883 Gene3D G3DSA:3.30.420.10 661 876 5.0E-27 T 01-11-2018 IPR036397 Ribonuclease H superfamily GO:0003676 AFULGI_00016690 0b5be8c6a852c9b7fc4391a23db8ab5c 883 Pfam PF02171 Piwi domain 602 871 5.7E-16 T 01-11-2018 IPR003165 Piwi domain GO:0003676 AFULGI_00016690 0b5be8c6a852c9b7fc4391a23db8ab5c 883 SUPERFAMILY SSF53098 475 874 4.3E-42 T 01-11-2018 IPR012337 Ribonuclease H-like superfamily AFULGI_00015410 c2b8414423089ca5543625f1f780b1dc 69 PIRSF PIRSF037465 1 69 2.0E-38 T 01-11-2018 IPR017211 Uncharacterised conserved protein UCP037465, zinc finger protein, AF1427 AFULGI_00015410 c2b8414423089ca5543625f1f780b1dc 69 SUPERFAMILY SSF57903 2 66 2.73E-5 T 01-11-2018 IPR011011 Zinc finger, FYVE/PHD-type AFULGI_00015410 c2b8414423089ca5543625f1f780b1dc 69 Pfam PF09947 Uncharacterized protein conserved in archaea (DUF2180) 1 67 4.1E-37 T 01-11-2018 IPR017211 Uncharacterised conserved protein UCP037465, zinc finger protein, AF1427 AFULGI_00010140 a94ffc3e9c2d57a19ccfd9cfbcf7071d 315 Pfam PF01435 Peptidase family M48 114 306 5.5E-13 T 01-11-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 AFULGI_00008750 455527f51e19717d8cd48b01995234a4 207 Pfam PF04893 Yip1 domain 3 190 1.5E-25 T 01-11-2018 IPR006977 Yip1 domain GO:0016020 AFULGI_00010020 3d37424b4fe5fa59f49d472266fa6c79 568 SUPERFAMILY SSF52954 447 560 3.78E-35 T 01-11-2018 AFULGI_00010020 3d37424b4fe5fa59f49d472266fa6c79 568 SUPERFAMILY SSF55681 4 463 3.46E-109 T 01-11-2018 AFULGI_00010020 3d37424b4fe5fa59f49d472266fa6c79 568 Hamap MF_00253_A Glycine--tRNA ligase [glyQS]. 1 553 55.417 T 01-11-2018 IPR022960 Glycine-tRNA ligase, archaeal GO:0004820 KEGG: 00970+6.1.1.14 AFULGI_00010020 3d37424b4fe5fa59f49d472266fa6c79 568 Gene3D G3DSA:3.40.50.800 458 567 1.1E-32 T 01-11-2018 IPR036621 Anticodon-binding domain superfamily AFULGI_00010020 3d37424b4fe5fa59f49d472266fa6c79 568 Gene3D G3DSA:1.20.1430.20 78 139 1.3E-149 T 01-11-2018 AFULGI_00010020 3d37424b4fe5fa59f49d472266fa6c79 568 PRINTS PR01043 Glycyl-tRNA synthetase signature 202 212 7.0E-56 T 01-11-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 AFULGI_00010020 3d37424b4fe5fa59f49d472266fa6c79 568 PRINTS PR01043 Glycyl-tRNA synthetase signature 134 146 7.0E-56 T 01-11-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 AFULGI_00010020 3d37424b4fe5fa59f49d472266fa6c79 568 PRINTS PR01043 Glycyl-tRNA synthetase signature 153 170 7.0E-56 T 01-11-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 AFULGI_00010020 3d37424b4fe5fa59f49d472266fa6c79 568 PRINTS PR01043 Glycyl-tRNA synthetase signature 185 202 7.0E-56 T 01-11-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 AFULGI_00010020 3d37424b4fe5fa59f49d472266fa6c79 568 PRINTS PR01043 Glycyl-tRNA synthetase signature 20 34 7.0E-56 T 01-11-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 AFULGI_00010020 3d37424b4fe5fa59f49d472266fa6c79 568 PRINTS PR01043 Glycyl-tRNA synthetase signature 416 428 7.0E-56 T 01-11-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 AFULGI_00010020 3d37424b4fe5fa59f49d472266fa6c79 568 PRINTS PR01043 Glycyl-tRNA synthetase signature 498 517 7.0E-56 T 01-11-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 AFULGI_00010020 3d37424b4fe5fa59f49d472266fa6c79 568 Pfam PF03129 Anticodon binding domain 461 550 1.7E-22 T 01-11-2018 IPR004154 Anticodon-binding AFULGI_00010020 3d37424b4fe5fa59f49d472266fa6c79 568 Gene3D G3DSA:3.30.930.10 7 438 1.3E-149 T 01-11-2018 AFULGI_00010020 3d37424b4fe5fa59f49d472266fa6c79 568 TIGRFAM TIGR00389 glyS_dimeric: glycine--tRNA ligase 2 551 1.3E-252 T 01-11-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 AFULGI_00010020 3d37424b4fe5fa59f49d472266fa6c79 568 Gene3D G3DSA:1.10.30.30 349 407 1.3E-149 T 01-11-2018 AFULGI_00010020 3d37424b4fe5fa59f49d472266fa6c79 568 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 153 223 4.6E-9 T 01-11-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFULGI_00013410 114ae125b1ccd55430f6d61a0840c5d1 244 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 8 22 - T 01-11-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 AFULGI_00013410 114ae125b1ccd55430f6d61a0840c5d1 244 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 4 212 1.5E-52 T 01-11-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 AFULGI_00013410 114ae125b1ccd55430f6d61a0840c5d1 244 SUPERFAMILY SSF53790 1 236 2.22E-73 T 01-11-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 AFULGI_00013410 114ae125b1ccd55430f6d61a0840c5d1 244 Gene3D G3DSA:3.40.1010.10 1 118 1.7E-45 T 01-11-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 AFULGI_00013410 114ae125b1ccd55430f6d61a0840c5d1 244 Gene3D G3DSA:3.30.950.10 119 243 3.6E-41 T 01-11-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 AFULGI_00013410 114ae125b1ccd55430f6d61a0840c5d1 244 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 3 235 5.5E-97 T 01-11-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0008168|GO:0019354 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 AFULGI_00018740 b9327489ded5b68bb2971b6ec8c2ac15 392 SUPERFAMILY SSF53383 15 388 2.04E-113 T 01-11-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFULGI_00018740 b9327489ded5b68bb2971b6ec8c2ac15 392 Gene3D G3DSA:3.40.640.10 32 392 7.1E-121 T 01-11-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFULGI_00018740 b9327489ded5b68bb2971b6ec8c2ac15 392 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 237 250 - T 01-11-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 AFULGI_00018740 b9327489ded5b68bb2971b6ec8c2ac15 392 Pfam PF00155 Aminotransferase class I and II 39 382 4.1E-62 T 01-11-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 AFULGI_00002810 1e0e30d41c1de522fa5fd20c6975bf14 317 SMART SM00893 3 185 1.3E-36 T 01-11-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 AFULGI_00002810 1e0e30d41c1de522fa5fd20c6975bf14 317 SUPERFAMILY SSF52402 1 186 2.3E-40 T 01-11-2018 AFULGI_00002810 1e0e30d41c1de522fa5fd20c6975bf14 317 Gene3D G3DSA:3.40.50.620 1 184 1.3E-41 T 01-11-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFULGI_00002810 1e0e30d41c1de522fa5fd20c6975bf14 317 SUPERFAMILY SSF52467 192 312 8.18E-47 T 01-11-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily AFULGI_00002810 1e0e30d41c1de522fa5fd20c6975bf14 317 PIRSF PIRSF000089 1 317 1.3E-107 T 01-11-2018 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 AFULGI_00002810 1e0e30d41c1de522fa5fd20c6975bf14 317 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 192 275 5.9E-35 T 01-11-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 AFULGI_00002810 1e0e30d41c1de522fa5fd20c6975bf14 317 Gene3D G3DSA:3.40.50.1220 187 317 2.4E-55 T 01-11-2018 AFULGI_00002810 1e0e30d41c1de522fa5fd20c6975bf14 317 Pfam PF01012 Electron transfer flavoprotein domain 11 169 9.5E-37 T 01-11-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 AFULGI_00011670 ea3d21d6d6b1d9e00e7ca111641bdf32 145 Gene3D G3DSA:2.60.120.630 1 141 9.0E-49 T 01-11-2018 IPR023131 Mth639-like domain superfamily AFULGI_00011670 ea3d21d6d6b1d9e00e7ca111641bdf32 145 Pfam PF04027 Domain of unknown function (DUF371) 4 135 3.9E-48 T 01-11-2018 IPR007171 Protein of unknown function DUF371 AFULGI_00013930 384f41dc3e3c00fcbfdb87465bc4db3e 134 PIRSF PIRSF000077 29 134 3.5E-39 T 01-11-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 AFULGI_00013930 384f41dc3e3c00fcbfdb87465bc4db3e 134 Gene3D G3DSA:3.40.30.10 25 134 1.3E-40 T 01-11-2018 AFULGI_00013930 384f41dc3e3c00fcbfdb87465bc4db3e 134 PRINTS PR00421 Thioredoxin family signature 58 67 1.3E-8 T 01-11-2018 AFULGI_00013930 384f41dc3e3c00fcbfdb87465bc4db3e 134 PRINTS PR00421 Thioredoxin family signature 98 109 1.3E-8 T 01-11-2018 AFULGI_00013930 384f41dc3e3c00fcbfdb87465bc4db3e 134 PRINTS PR00421 Thioredoxin family signature 50 58 1.3E-8 T 01-11-2018 AFULGI_00013930 384f41dc3e3c00fcbfdb87465bc4db3e 134 Pfam PF00085 Thioredoxin 33 132 9.6E-35 T 01-11-2018 IPR013766 Thioredoxin domain GO:0045454 AFULGI_00013930 384f41dc3e3c00fcbfdb87465bc4db3e 134 SUPERFAMILY SSF52833 2 134 4.76E-44 T 01-11-2018 IPR036249 Thioredoxin-like superfamily AFULGI_00013930 384f41dc3e3c00fcbfdb87465bc4db3e 134 TIGRFAM TIGR01068 thioredoxin: thioredoxin 36 133 2.8E-42 T 01-11-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 AFULGI_00003790 4cd72c337507745072689fd348946cce 524 SUPERFAMILY SSF56821 21 421 1.1E-177 T 01-11-2018 IPR011254 Prismane-like superfamily GO:0003824|GO:0016491|GO:0055114 AFULGI_00003790 4cd72c337507745072689fd348946cce 524 Pfam PF03598 CO dehydrogenase/acetyl-CoA synthase complex beta subunit 25 178 1.7E-61 T 01-11-2018 IPR004461 CO dehydrogenase/acetyl-CoA synthase complex beta subunit GO:0006084|GO:0018492 KEGG: 00720+2.3.1.169|MetaCyc: PWY-7784 AFULGI_00003790 4cd72c337507745072689fd348946cce 524 Gene3D G3DSA:3.30.1650.10 23 201 1.8E-57 T 01-11-2018 IPR038571 Bifunctional carbon monoxide dehydrogenase/acetyl-coa synthase, domain 3 superfamily KEGG: 00720+2.3.1.169|MetaCyc: PWY-7784 AFULGI_00003790 4cd72c337507745072689fd348946cce 524 Gene3D G3DSA:3.40.1470.10 305 423 3.5E-45 T 01-11-2018 AFULGI_00003790 4cd72c337507745072689fd348946cce 524 Hamap MF_01138 Acetyl-CoA decarbonylase/synthase complex subunit beta [cdhC]. 22 516 60.898 T 01-11-2018 IPR023432 Acetyl-CoA decarbonylase/synthase complex subunit beta, archaeal GO:0006084|GO:0018492 KEGG: 00720+2.3.1.169|MetaCyc: PWY-7784 AFULGI_00003790 4cd72c337507745072689fd348946cce 524 Gene3D G3DSA:3.40.970.20 202 290 1.5E-36 T 01-11-2018 AFULGI_00003790 4cd72c337507745072689fd348946cce 524 TIGRFAM TIGR00316 cdhC: CO dehydrogenase/CO-methylating acetyl-CoA synthase complex, beta subunit 22 515 4.3E-260 T 01-11-2018 IPR004461 CO dehydrogenase/acetyl-CoA synthase complex beta subunit GO:0006084|GO:0018492 KEGG: 00720+2.3.1.169|MetaCyc: PWY-7784 AFULGI_00003700 2b679b9cb32ea1f275a5c94727c29ded 339 Gene3D G3DSA:3.40.50.10470 142 339 5.4E-72 T 01-11-2018 AFULGI_00003700 2b679b9cb32ea1f275a5c94727c29ded 339 TIGRFAM TIGR00512 salvage_mtnA: S-methyl-5-thioribose-1-phosphate isomerase 5 326 9.6E-119 T 01-11-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 AFULGI_00003700 2b679b9cb32ea1f275a5c94727c29ded 339 Pfam PF01008 Initiation factor 2 subunit family 42 327 2.3E-96 T 01-11-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 AFULGI_00003700 2b679b9cb32ea1f275a5c94727c29ded 339 SUPERFAMILY SSF100950 5 331 5.86E-116 T 01-11-2018 IPR037171 NagB/RpiA transferase-like AFULGI_00003700 2b679b9cb32ea1f275a5c94727c29ded 339 Gene3D G3DSA:1.20.120.420 1 140 3.3E-52 T 01-11-2018 IPR027363 Methylthioribose-1-phosphate isomerase, N-terminal KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 AFULGI_00003700 2b679b9cb32ea1f275a5c94727c29ded 339 Hamap MF_01678 Putative methylthioribose-1-phosphate isomerase [mtnA]. 1 337 36.846 T 01-11-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 AFULGI_00003700 2b679b9cb32ea1f275a5c94727c29ded 339 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 27 327 2.9E-139 T 01-11-2018 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 AFULGI_00022090 ea30dc7342aa79d60c4da88fe02cb8b6 108 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 48 101 2.0E-26 T 01-11-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 AFULGI_00022090 ea30dc7342aa79d60c4da88fe02cb8b6 108 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 1 102 31.917 T 01-11-2018 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 AFULGI_00022090 ea30dc7342aa79d60c4da88fe02cb8b6 108 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 25 98 4.6E-37 T 01-11-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 AFULGI_00022090 ea30dc7342aa79d60c4da88fe02cb8b6 108 SUPERFAMILY SSF141734 3 105 8.24E-50 T 01-11-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 AFULGI_00022090 ea30dc7342aa79d60c4da88fe02cb8b6 108 Gene3D G3DSA:3.10.20.400 1 89 1.3E-42 T 01-11-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 AFULGI_00007400 a0aeb7e4c4f6db21c5dcd3c6680514f8 91 SUPERFAMILY SSF101386 1 77 1.31E-19 T 01-11-2018 AFULGI_00007400 a0aeb7e4c4f6db21c5dcd3c6680514f8 91 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 24 81 1.3E-12 T 01-11-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core AFULGI_00007400 a0aeb7e4c4f6db21c5dcd3c6680514f8 91 Gene3D G3DSA:1.10.287.1080 1 78 1.6E-21 T 01-11-2018 AFULGI_00025170 b9ee4af9f78550bdfc1875bb127c30ea 114 Pfam PF13601 Winged helix DNA-binding domain 16 85 5.7E-11 T 01-11-2018 IPR027395 Winged helix DNA-binding domain AFULGI_00025170 b9ee4af9f78550bdfc1875bb127c30ea 114 SUPERFAMILY SSF46785 19 112 5.94E-16 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00025170 b9ee4af9f78550bdfc1875bb127c30ea 114 Gene3D G3DSA:1.10.10.10 3 94 2.4E-15 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00008310 b1b45460113220ce91788493dc7837a9 245 SUPERFAMILY SSF52518 4 207 1.11E-63 T 01-11-2018 IPR029061 Thiamin diphosphate-binding fold AFULGI_00008310 b1b45460113220ce91788493dc7837a9 245 Gene3D G3DSA:3.40.50.970 17 212 2.2E-20 T 01-11-2018 AFULGI_00008310 b1b45460113220ce91788493dc7837a9 245 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 39 186 8.8E-29 T 01-11-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 AFULGI_00012820 1d96e9513ee9ae2a53504c3e4ab596e7 115 PIRSF PIRSF004977 1 115 1.4E-53 T 01-11-2018 IPR012017 Uncharacterised conserved protein UCP004977 AFULGI_00012820 1d96e9513ee9ae2a53504c3e4ab596e7 115 Pfam PF09846 Uncharacterized protein conserved in archaea (DUF2073) 14 113 5.9E-42 T 01-11-2018 IPR012017 Uncharacterised conserved protein UCP004977 AFULGI_00008150 c4582b61b8eed5799f060d9ec556bbf3 457 SUPERFAMILY SSF64182 4 456 8.02E-59 T 01-11-2018 IPR038763 DHH phosphoesterase superfamily AFULGI_00008150 c4582b61b8eed5799f060d9ec556bbf3 457 Pfam PF02272 DHHA1 domain 349 451 1.2E-19 T 01-11-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 AFULGI_00008150 c4582b61b8eed5799f060d9ec556bbf3 457 Gene3D G3DSA:3.10.310.30 334 454 3.4E-8 T 01-11-2018 AFULGI_00008150 c4582b61b8eed5799f060d9ec556bbf3 457 Gene3D G3DSA:3.90.1640.30 1 204 3.2E-14 T 01-11-2018 AFULGI_00001540 cd87154134b7c610cf05d23bf0062f5b 92 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 10 21 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFULGI_00001540 cd87154134b7c610cf05d23bf0062f5b 92 Gene3D G3DSA:3.30.70.20 1 59 4.3E-15 T 01-11-2018 AFULGI_00001540 cd87154134b7c610cf05d23bf0062f5b 92 SUPERFAMILY SSF54862 2 60 5.73E-22 T 01-11-2018 AFULGI_00001540 cd87154134b7c610cf05d23bf0062f5b 92 Pfam PF12798 4Fe-4S binding domain 40 54 0.03 T 01-11-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFULGI_00001540 cd87154134b7c610cf05d23bf0062f5b 92 Pfam PF00037 4Fe-4S binding domain 4 25 8.2E-11 T 01-11-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFULGI_00009250 255a323d915c8c924256ac98f9886293 337 SUPERFAMILY SSF52540 2 332 1.59E-103 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00009250 255a323d915c8c924256ac98f9886293 337 Gene3D G3DSA:3.40.440.10 1 336 2.9E-127 T 01-11-2018 AFULGI_00009250 255a323d915c8c924256ac98f9886293 337 SMART SM00788 3 331 8.8E-158 T 01-11-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 AFULGI_00009250 255a323d915c8c924256ac98f9886293 337 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 337 96.352 T 01-11-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 AFULGI_00009250 255a323d915c8c924256ac98f9886293 337 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 10 17 - T 01-11-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 AFULGI_00009250 255a323d915c8c924256ac98f9886293 337 Pfam PF00709 Adenylosuccinate synthetase 289 330 1.7E-5 T 01-11-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 AFULGI_00009250 255a323d915c8c924256ac98f9886293 337 Pfam PF00709 Adenylosuccinate synthetase 4 146 1.0E-35 T 01-11-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 AFULGI_00009250 255a323d915c8c924256ac98f9886293 337 Pfam PF00709 Adenylosuccinate synthetase 148 287 9.1E-41 T 01-11-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 AFULGI_00021860 d457d82710e5d5590b0949a7f178331f 198 SUPERFAMILY SSF89392 25 194 1.57E-11 T 01-11-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX AFULGI_00021860 d457d82710e5d5590b0949a7f178331f 198 Gene3D G3DSA:2.50.20.10 18 196 8.3E-14 T 01-11-2018 AFULGI_00010260 be1ac732f5beaebf6ad60efa064bed51 240 Pfam PF06847 Archaeal Peptidase A24 C-terminus Type II 148 229 3.3E-19 T 01-11-2018 IPR009655 Preflagellin peptidase, C-terminal AFULGI_00010260 be1ac732f5beaebf6ad60efa064bed51 240 Gene3D G3DSA:3.30.1360.160 126 211 9.9E-24 T 01-11-2018 AFULGI_00010260 be1ac732f5beaebf6ad60efa064bed51 240 Pfam PF01478 Type IV leader peptidase family 8 127 3.0E-13 T 01-11-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 AFULGI_00010260 be1ac732f5beaebf6ad60efa064bed51 240 Gene3D G3DSA:1.20.120.1220 26 230 9.9E-24 T 01-11-2018 AFULGI_00007150 79ba18a27a7b0814ef0dc4b88009c231 308 SUPERFAMILY SSF51735 4 151 1.13E-13 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily AFULGI_00007150 79ba18a27a7b0814ef0dc4b88009c231 308 Gene3D G3DSA:3.40.50.720 1 154 6.0E-18 T 01-11-2018 AFULGI_00026320 d0f46e0a15a91d56dd6ea20ff0dc4466 148 Gene3D G3DSA:3.40.50.360 1 146 9.8E-6 T 01-11-2018 IPR029039 Flavoprotein-like superfamily AFULGI_00026320 d0f46e0a15a91d56dd6ea20ff0dc4466 148 SUPERFAMILY SSF52218 1 143 2.62E-9 T 01-11-2018 IPR029039 Flavoprotein-like superfamily AFULGI_00010840 720a31fc502c8419f26de5eab1222900 396 Gene3D G3DSA:3.40.50.10540 5 390 3.7E-140 T 01-11-2018 IPR023606 CoA-transferase family III domain superfamily AFULGI_00010840 720a31fc502c8419f26de5eab1222900 396 SUPERFAMILY SSF89796 4 396 4.32E-135 T 01-11-2018 IPR023606 CoA-transferase family III domain superfamily AFULGI_00010840 720a31fc502c8419f26de5eab1222900 396 Pfam PF02515 CoA-transferase family III 8 373 6.2E-126 T 01-11-2018 IPR003673 CoA-transferase family III GO:0003824 AFULGI_00010840 720a31fc502c8419f26de5eab1222900 396 Gene3D G3DSA:3.30.1540.10 233 325 3.7E-140 T 01-11-2018 AFULGI_00006930 b2160fa437d29ec7c9e38516eef13346 114 SUPERFAMILY SSF81301 22 107 2.17E-20 T 01-11-2018 AFULGI_00006930 b2160fa437d29ec7c9e38516eef13346 114 Gene3D G3DSA:3.30.460.10 19 114 1.4E-37 T 01-11-2018 AFULGI_00006930 b2160fa437d29ec7c9e38516eef13346 114 Pfam PF01909 Nucleotidyltransferase domain 22 110 1.6E-13 T 01-11-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 AFULGI_00023550 127705081c30345aabc5a38bf93a1b99 93 TIGRFAM TIGR01195 oadG_fam: sodium pump decarboxylases, gamma subunit 1 70 1.0E-19 T 01-11-2018 IPR005899 Sodium ion-translocating decarboxylase GO:0008948|GO:0015081|GO:0016020|GO:0036376 KEGG: 00620+4.1.1.3 AFULGI_00023550 127705081c30345aabc5a38bf93a1b99 93 Pfam PF04277 Oxaloacetate decarboxylase, gamma chain 5 64 1.6E-7 T 01-11-2018 IPR005899 Sodium ion-translocating decarboxylase GO:0008948|GO:0015081|GO:0016020|GO:0036376 KEGG: 00620+4.1.1.3 AFULGI_00019790 82c751949e35eb4fe3ddd04fefb7a1f9 356 Gene3D G3DSA:3.40.50.2000 1 186 3.0E-34 T 01-11-2018 AFULGI_00019790 82c751949e35eb4fe3ddd04fefb7a1f9 356 Pfam PF13439 Glycosyltransferase Family 4 14 173 5.5E-24 T 01-11-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 AFULGI_00019790 82c751949e35eb4fe3ddd04fefb7a1f9 356 SUPERFAMILY SSF53756 2 356 7.18E-87 T 01-11-2018 AFULGI_00019790 82c751949e35eb4fe3ddd04fefb7a1f9 356 Pfam PF00534 Glycosyl transferases group 1 174 332 2.1E-40 T 01-11-2018 IPR001296 Glycosyl transferase, family 1 AFULGI_00019790 82c751949e35eb4fe3ddd04fefb7a1f9 356 Gene3D G3DSA:3.40.50.2000 187 346 8.2E-44 T 01-11-2018 AFULGI_00024070 69d8e70da87e839ab30412f8eed98936 283 SUPERFAMILY SSF160240 195 275 1.7E-15 T 01-11-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 AFULGI_00024070 69d8e70da87e839ab30412f8eed98936 283 Pfam PF01545 Cation efflux family 4 191 5.6E-33 T 01-11-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 AFULGI_00024070 69d8e70da87e839ab30412f8eed98936 283 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 4 276 6.3E-71 T 01-11-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 AFULGI_00024070 69d8e70da87e839ab30412f8eed98936 283 Gene3D G3DSA:3.30.70.1350 193 276 2.6E-13 T 01-11-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 AFULGI_00024070 69d8e70da87e839ab30412f8eed98936 283 Pfam PF16916 Dimerisation domain of Zinc Transporter 197 274 3.7E-16 T 01-11-2018 IPR027470 Cation efflux protein, cytoplasmic domain AFULGI_00024070 69d8e70da87e839ab30412f8eed98936 283 SUPERFAMILY SSF161111 5 193 5.23E-32 T 01-11-2018 IPR027469 Cation efflux transmembrane domain superfamily AFULGI_00024070 69d8e70da87e839ab30412f8eed98936 283 Gene3D G3DSA:1.20.1510.10 4 192 3.4E-34 T 01-11-2018 IPR027469 Cation efflux transmembrane domain superfamily AFULGI_00000230 767d6fe6ddf4e9ca2e31ca5a4b076dae 394 Gene3D G3DSA:1.20.1250.20 199 392 3.4E-17 T 01-11-2018 AFULGI_00000230 767d6fe6ddf4e9ca2e31ca5a4b076dae 394 SUPERFAMILY SSF103473 4 391 8.89E-48 T 01-11-2018 IPR036259 MFS transporter superfamily AFULGI_00000230 767d6fe6ddf4e9ca2e31ca5a4b076dae 394 Gene3D G3DSA:1.20.1250.20 2 193 8.9E-26 T 01-11-2018 AFULGI_00000230 767d6fe6ddf4e9ca2e31ca5a4b076dae 394 Pfam PF07690 Major Facilitator Superfamily 20 354 2.0E-35 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFULGI_00018120 0b0457f371722ea0daacc3889991d9a0 224 Pfam PF02616 Segregation and condensation protein ScpA 1 222 1.3E-19 T 01-11-2018 IPR003768 Segregation and condensation protein A AFULGI_00021030 e4bace5f4e700f6aec76b51c291285b4 622 SUPERFAMILY SSF56821 7 622 1.28E-176 T 01-11-2018 IPR011254 Prismane-like superfamily GO:0003824|GO:0016491|GO:0055114 AFULGI_00021030 e4bace5f4e700f6aec76b51c291285b4 622 Pfam PF03063 Prismane/CO dehydrogenase family 48 602 9.4E-138 T 01-11-2018 IPR004137 Hydroxylamine reductase/Ni-containing CO dehydrogenase GO:0016491|GO:0055114 KEGG: 00910+1.7.99.1 AFULGI_00021030 e4bace5f4e700f6aec76b51c291285b4 622 TIGRFAM TIGR01702 CO_DH_cata: carbon-monoxide dehydrogenase, catalytic subunit 8 622 6.6E-285 T 01-11-2018 IPR010047 Ni-containing CO dehydrogenase GO:0006091|GO:0016151|GO:0018492|GO:0051539|GO:0055114 KEGG: 00633+1.2.7.4|KEGG: 00680+1.2.7.4|KEGG: 00720+1.2.7.4|MetaCyc: PWY-5372|MetaCyc: PWY-6780|MetaCyc: PWY-7784 AFULGI_00021030 e4bace5f4e700f6aec76b51c291285b4 622 Gene3D G3DSA:3.40.50.2030 407 619 2.8E-75 T 01-11-2018 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 AFULGI_00021030 e4bace5f4e700f6aec76b51c291285b4 622 Gene3D G3DSA:1.20.1270.30 62 232 1.4E-46 T 01-11-2018 IPR016101 CO dehydrogenase, alpha-bundle GO:0006091|GO:0016151|GO:0018492|GO:0051539|GO:0055114 KEGG: 00633+1.2.7.4|KEGG: 00680+1.2.7.4|KEGG: 00720+1.2.7.4|MetaCyc: PWY-5372|MetaCyc: PWY-6780|MetaCyc: PWY-7784 AFULGI_00021030 e4bace5f4e700f6aec76b51c291285b4 622 PIRSF PIRSF005023 1 622 1.5E-261 T 01-11-2018 IPR010047 Ni-containing CO dehydrogenase GO:0006091|GO:0016151|GO:0018492|GO:0051539|GO:0055114 KEGG: 00633+1.2.7.4|KEGG: 00680+1.2.7.4|KEGG: 00720+1.2.7.4|MetaCyc: PWY-5372|MetaCyc: PWY-6780|MetaCyc: PWY-7784 AFULGI_00021030 e4bace5f4e700f6aec76b51c291285b4 622 Gene3D G3DSA:3.40.50.2030 233 406 4.9E-51 T 01-11-2018 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 AFULGI_00001140 031160b59ad49c97d9100b204a998488 320 Pfam PF13353 4Fe-4S single cluster domain 98 191 1.2E-6 T 01-11-2018 AFULGI_00001140 031160b59ad49c97d9100b204a998488 320 SUPERFAMILY SSF102114 75 311 1.31E-20 T 01-11-2018 AFULGI_00001140 031160b59ad49c97d9100b204a998488 320 Pfam PF04055 Radical SAM superfamily 104 265 2.4E-19 T 01-11-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFULGI_00001140 031160b59ad49c97d9100b204a998488 320 PIRSF PIRSF004869 11 320 2.8E-81 T 01-11-2018 IPR016431 Pyruvate-formate lyase-activating enzyme, predicted AFULGI_00001140 031160b59ad49c97d9100b204a998488 320 Gene3D G3DSA:3.20.20.70 92 311 2.2E-27 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFULGI_00026560 37b0e333639585b95ddab600b2b554b6 249 Gene3D G3DSA:2.60.200.30 102 226 4.3E-88 T 01-11-2018 IPR017437 ATP-NAD kinase, PpnK-type, C-terminal GO:0003951|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 AFULGI_00026560 37b0e333639585b95ddab600b2b554b6 249 SUPERFAMILY SSF111331 5 232 5.49E-57 T 01-11-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily AFULGI_00026560 37b0e333639585b95ddab600b2b554b6 249 Pfam PF01513 ATP-NAD kinase 38 231 6.2E-40 T 01-11-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 AFULGI_00026560 37b0e333639585b95ddab600b2b554b6 249 Hamap MF_00361 NAD kinase [nadK]. 1 247 23.555 T 01-11-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 AFULGI_00026560 37b0e333639585b95ddab600b2b554b6 249 Gene3D G3DSA:3.40.50.10330 15 238 4.3E-88 T 01-11-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 AFULGI_00018970 3eaf0356216e5b4e1040e4c83a30f660 257 Gene3D G3DSA:3.60.110.10 1 257 1.7E-40 T 01-11-2018 IPR036526 Carbon-nitrogen hydrolase superfamily AFULGI_00018970 3eaf0356216e5b4e1040e4c83a30f660 257 SUPERFAMILY SSF56317 1 252 1.26E-42 T 01-11-2018 IPR036526 Carbon-nitrogen hydrolase superfamily AFULGI_00018970 3eaf0356216e5b4e1040e4c83a30f660 257 Pfam PF00795 Carbon-nitrogen hydrolase 3 233 4.7E-38 T 01-11-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 AFULGI_00018590 6598f240ff1aec2f4a7451ead80e2832 345 Gene3D G3DSA:3.40.50.300 3 242 1.2E-77 T 01-11-2018 AFULGI_00018590 6598f240ff1aec2f4a7451ead80e2832 345 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFULGI_00018590 6598f240ff1aec2f4a7451ead80e2832 345 Gene3D G3DSA:2.40.50.140 276 334 2.8E-5 T 01-11-2018 AFULGI_00018590 6598f240ff1aec2f4a7451ead80e2832 345 SMART SM00382 30 214 4.1E-18 T 01-11-2018 IPR003593 AAA+ ATPase domain AFULGI_00018590 6598f240ff1aec2f4a7451ead80e2832 345 SUPERFAMILY SSF50331 240 344 7.14E-18 T 01-11-2018 IPR008995 Molybdate/tungstate binding, C-terminal AFULGI_00018590 6598f240ff1aec2f4a7451ead80e2832 345 SUPERFAMILY SSF52540 6 248 2.79E-86 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00018590 6598f240ff1aec2f4a7451ead80e2832 345 Pfam PF00005 ABC transporter 21 165 1.9E-35 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFULGI_00018590 6598f240ff1aec2f4a7451ead80e2832 345 Pfam PF08402 TOBE domain 273 343 3.2E-13 T 01-11-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 AFULGI_00023040 f727b202dae83ac3a79ebe0ecdf34ccc 313 Pfam PF01008 Initiation factor 2 subunit family 15 284 7.0E-99 T 01-11-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 AFULGI_00023040 f727b202dae83ac3a79ebe0ecdf34ccc 313 SUPERFAMILY SSF100950 3 296 4.88E-98 T 01-11-2018 IPR037171 NagB/RpiA transferase-like AFULGI_00023040 f727b202dae83ac3a79ebe0ecdf34ccc 313 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 1 284 4.1E-114 T 01-11-2018 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 AFULGI_00023040 f727b202dae83ac3a79ebe0ecdf34ccc 313 Gene3D G3DSA:3.40.50.10470 98 284 2.6E-97 T 01-11-2018 AFULGI_00023040 f727b202dae83ac3a79ebe0ecdf34ccc 313 Gene3D G3DSA:1.20.120.420 6 97 2.6E-97 T 01-11-2018 IPR027363 Methylthioribose-1-phosphate isomerase, N-terminal KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 AFULGI_00023040 f727b202dae83ac3a79ebe0ecdf34ccc 313 TIGRFAM TIGR00511 ribulose_e2b2: ribose-1,5-bisphosphate isomerase, e2b2 family 3 296 4.9E-147 T 01-11-2018 IPR005250 Ribose-1,5-bisphosphate isomerase, e2b2 family MetaCyc: PWY-5532 AFULGI_00007290 9890b9557fe77f8ca739f110363833fc 233 Gene3D G3DSA:3.10.520.10 1 220 2.7E-65 T 01-11-2018 AFULGI_00007290 9890b9557fe77f8ca739f110363833fc 233 SUPERFAMILY SSF143631 2 219 3.4E-65 T 01-11-2018 IPR003374 ApbE-like superfamily AFULGI_00007290 9890b9557fe77f8ca739f110363833fc 233 PIRSF PIRSF006421 1 233 1.3E-83 T 01-11-2018 IPR007183 Uncharacterised protein family UPF0280 AFULGI_00007290 9890b9557fe77f8ca739f110363833fc 233 Hamap MF_01079 UPF0280 protein . 1 233 35.915 T 01-11-2018 IPR037456 MA1715-like AFULGI_00005540 0d3cb9c58391ee54a2c75b045b811c30 308 Gene3D G3DSA:1.20.950.20 84 246 4.8E-14 T 01-11-2018 AFULGI_00005540 0d3cb9c58391ee54a2c75b045b811c30 308 SUPERFAMILY SSF103501 81 245 2.62E-20 T 01-11-2018 IPR036197 NarG-like superfamily AFULGI_00005540 0d3cb9c58391ee54a2c75b045b811c30 308 Pfam PF02665 Nitrate reductase gamma subunit 90 244 8.8E-11 T 01-11-2018 IPR023234 NarG-like domain AFULGI_00014420 3bf05ef93ab916ae8946da8774c14238 330 SUPERFAMILY SSF54197 21 168 8.29E-14 T 01-11-2018 IPR036265 HIT-like superfamily AFULGI_00014420 3bf05ef93ab916ae8946da8774c14238 330 Gene3D G3DSA:3.30.428.10 137 327 5.6E-15 T 01-11-2018 IPR036265 HIT-like superfamily AFULGI_00020980 bcc33912d21e7ba9bc045d1c27233535 243 Pfam PF02361 Cobalt transport protein 27 212 3.8E-24 T 01-11-2018 IPR003339 ABC/ECF transporter, transmembrane component AFULGI_00020980 bcc33912d21e7ba9bc045d1c27233535 243 TIGRFAM TIGR02454 ECF_T_CbiQ: cobalt ECF transporter T component CbiQ 33 211 9.6E-42 T 01-11-2018 IPR012809 Cobalt ECF transporter T component CbiQ GO:0005887|GO:0006824|GO:0043190 AFULGI_00020450 0e5853aad869a37b8a5c7bf5495c6865 392 Gene3D G3DSA:3.40.50.720 4 381 2.7E-157 T 01-11-2018 AFULGI_00020450 0e5853aad869a37b8a5c7bf5495c6865 392 SUPERFAMILY SSF51735 1 389 6.22E-70 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily AFULGI_00020450 0e5853aad869a37b8a5c7bf5495c6865 392 Pfam PF01658 Myo-inositol-1-phosphate synthase 229 332 2.6E-24 T 01-11-2018 IPR013021 Myo-inositol-1-phosphate synthase, GAPDH-like KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 AFULGI_00020450 0e5853aad869a37b8a5c7bf5495c6865 392 Gene3D G3DSA:3.30.360.10 229 329 2.7E-157 T 01-11-2018 AFULGI_00020450 0e5853aad869a37b8a5c7bf5495c6865 392 PIRSF PIRSF015578 1 392 9.3E-117 T 01-11-2018 IPR002587 Myo-inositol-1-phosphate synthase GO:0004512|GO:0006021|GO:0008654 KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 AFULGI_00020450 0e5853aad869a37b8a5c7bf5495c6865 392 SUPERFAMILY SSF55347 228 332 4.45E-32 T 01-11-2018 AFULGI_00020450 0e5853aad869a37b8a5c7bf5495c6865 392 Pfam PF07994 Myo-inositol-1-phosphate synthase 1 381 5.7E-44 T 01-11-2018 IPR002587 Myo-inositol-1-phosphate synthase GO:0004512|GO:0006021|GO:0008654 KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 AFULGI_00018730 298c56d292eae35f2cc7edf0e8958f11 163 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 1.4E-5 T 01-11-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFULGI_00018730 298c56d292eae35f2cc7edf0e8958f11 163 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 1.4E-5 T 01-11-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFULGI_00018730 298c56d292eae35f2cc7edf0e8958f11 163 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 1.4E-5 T 01-11-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFULGI_00018730 298c56d292eae35f2cc7edf0e8958f11 163 Gene3D G3DSA:1.10.10.10 2 52 1.8E-9 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00018730 298c56d292eae35f2cc7edf0e8958f11 163 SUPERFAMILY SSF46785 3 59 9.1E-9 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00018730 298c56d292eae35f2cc7edf0e8958f11 163 SUPERFAMILY SSF54909 66 147 4.29E-17 T 01-11-2018 IPR011008 Dimeric alpha-beta barrel AFULGI_00018730 298c56d292eae35f2cc7edf0e8958f11 163 Gene3D G3DSA:3.30.70.920 53 150 6.9E-21 T 01-11-2018 AFULGI_00018730 298c56d292eae35f2cc7edf0e8958f11 163 Pfam PF01037 Lrp/AsnC ligand binding domain 70 142 7.8E-16 T 01-11-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain AFULGI_00018730 298c56d292eae35f2cc7edf0e8958f11 163 SMART SM00344 3 111 2.2E-10 T 01-11-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 AFULGI_00018730 298c56d292eae35f2cc7edf0e8958f11 163 Pfam PF13412 Winged helix-turn-helix DNA-binding 5 47 3.3E-7 T 01-11-2018 AFULGI_00023850 730faf3b07c0e3526f826f30f28989bc 295 SUPERFAMILY SSF48150 116 285 6.6E-36 T 01-11-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 AFULGI_00023850 730faf3b07c0e3526f826f30f28989bc 295 Gene3D G3DSA:1.10.340.30 114 233 2.6E-34 T 01-11-2018 AFULGI_00023850 730faf3b07c0e3526f826f30f28989bc 295 SMART SM00478 127 283 1.6E-44 T 01-11-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 AFULGI_00023850 730faf3b07c0e3526f826f30f28989bc 295 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 124 270 6.7E-20 T 01-11-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 AFULGI_00023850 730faf3b07c0e3526f826f30f28989bc 295 Gene3D G3DSA:1.10.1670.10 234 295 6.0E-37 T 01-11-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 AFULGI_00023850 730faf3b07c0e3526f826f30f28989bc 295 Gene3D G3DSA:3.30.310.20 1 113 2.3E-62 T 01-11-2018 IPR037046 DNA-3-methyladenine glycosylase AlkA, N-terminal domain superfamily AFULGI_00019990 737cb5d6b78486c4dee2396ed850df24 236 SMART SM00849 20 199 7.3E-32 T 01-11-2018 IPR001279 Metallo-beta-lactamase AFULGI_00019990 737cb5d6b78486c4dee2396ed850df24 236 Pfam PF00753 Metallo-beta-lactamase superfamily 17 199 9.4E-38 T 01-11-2018 IPR001279 Metallo-beta-lactamase AFULGI_00019990 737cb5d6b78486c4dee2396ed850df24 236 Gene3D G3DSA:3.60.15.10 2 231 6.3E-49 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFULGI_00019990 737cb5d6b78486c4dee2396ed850df24 236 SUPERFAMILY SSF56281 4 217 1.27E-47 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFULGI_00019460 bf6bafc4be568ef84fa427f89caf2c91 157 Pfam PF01022 Bacterial regulatory protein, arsR family 7 51 6.0E-17 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFULGI_00019460 bf6bafc4be568ef84fa427f89caf2c91 157 SUPERFAMILY SSF46785 7 72 1.48E-22 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00019460 bf6bafc4be568ef84fa427f89caf2c91 157 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 48 63 1.5E-8 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFULGI_00019460 bf6bafc4be568ef84fa427f89caf2c91 157 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 1 16 1.5E-8 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFULGI_00019460 bf6bafc4be568ef84fa427f89caf2c91 157 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 33 48 1.5E-8 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFULGI_00019460 bf6bafc4be568ef84fa427f89caf2c91 157 SMART SM00418 3 82 8.7E-22 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFULGI_00019460 bf6bafc4be568ef84fa427f89caf2c91 157 Gene3D G3DSA:1.10.10.10 4 86 9.8E-20 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00020530 af506206ef9150f24353a0fb3b7919af 231 Pfam PF00588 SpoU rRNA Methylase family 6 149 3.1E-30 T 01-11-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 AFULGI_00020530 af506206ef9150f24353a0fb3b7919af 231 PIRSF PIRSF004808 1 230 6.8E-65 T 01-11-2018 IPR004384 RNA methyltransferase TrmJ/LasT GO:0006396|GO:0008173 AFULGI_00020530 af506206ef9150f24353a0fb3b7919af 231 SUPERFAMILY SSF75217 3 151 2.35E-30 T 01-11-2018 IPR029028 Alpha/beta knot methyltransferases AFULGI_00020530 af506206ef9150f24353a0fb3b7919af 231 TIGRFAM TIGR00050 rRNA_methyl_1: RNA methyltransferase, TrmH family, group 1 6 226 4.3E-86 T 01-11-2018 IPR004384 RNA methyltransferase TrmJ/LasT GO:0006396|GO:0008173 AFULGI_00020530 af506206ef9150f24353a0fb3b7919af 231 Gene3D G3DSA:3.40.1280.10 2 157 3.2E-43 T 01-11-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal AFULGI_00006840 efb50411b0f7b122f0dcf0840a212815 346 Gene3D G3DSA:3.40.50.2000 6 141 2.2E-25 T 01-11-2018 AFULGI_00006840 efb50411b0f7b122f0dcf0840a212815 346 Pfam PF13692 Glycosyl transferases group 1 160 266 5.1E-19 T 01-11-2018 AFULGI_00006840 efb50411b0f7b122f0dcf0840a212815 346 Gene3D G3DSA:3.40.50.2000 142 266 2.2E-25 T 01-11-2018 AFULGI_00006840 efb50411b0f7b122f0dcf0840a212815 346 SUPERFAMILY SSF53756 40 326 1.06E-30 T 01-11-2018 AFULGI_00005090 bdfa4496a0f156b7f819019639bdcc5d 269 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 150 161 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFULGI_00005090 bdfa4496a0f156b7f819019639bdcc5d 269 Pfam PF13247 4Fe-4S dicluster domain 112 166 1.2E-10 T 01-11-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFULGI_00005090 bdfa4496a0f156b7f819019639bdcc5d 269 Gene3D G3DSA:3.30.70.20 58 268 1.5E-50 T 01-11-2018 AFULGI_00005090 bdfa4496a0f156b7f819019639bdcc5d 269 SUPERFAMILY SSF54862 39 264 1.36E-49 T 01-11-2018 AFULGI_00013490 534cf031408b433f8bccb501ab553a56 239 Pfam PF09754 PAC2 family 19 222 4.7E-46 T 01-11-2018 IPR019151 Proteasome assembly chaperone 2 AFULGI_00013490 534cf031408b433f8bccb501ab553a56 239 Gene3D G3DSA:3.40.50.10900 3 239 2.4E-61 T 01-11-2018 IPR038389 Proteasome assembly chaperone 2 superfamily AFULGI_00013490 534cf031408b433f8bccb501ab553a56 239 SUPERFAMILY SSF159659 4 231 1.83E-50 T 01-11-2018 AFULGI_00013490 534cf031408b433f8bccb501ab553a56 239 TIGRFAM TIGR00161 TIGR00161: TIGR00161 family protein 1 238 2.8E-122 T 01-11-2018 IPR004425 Conserved hypothetical protein CHP00061 AFULGI_00005670 c1c63be25d959c5315f628d375d89dae 380 SUPERFAMILY SSF51905 195 362 3.2E-11 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFULGI_00005670 c1c63be25d959c5315f628d375d89dae 380 SUPERFAMILY SSF51905 118 250 9.83E-34 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFULGI_00005670 c1c63be25d959c5315f628d375d89dae 380 Gene3D G3DSA:3.50.50.100 1 379 1.4E-94 T 01-11-2018 AFULGI_00005670 c1c63be25d959c5315f628d375d89dae 380 SUPERFAMILY SSF51905 1 151 3.2E-24 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFULGI_00005670 c1c63be25d959c5315f628d375d89dae 380 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 3 25 7.2E-5 T 01-11-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFULGI_00005670 c1c63be25d959c5315f628d375d89dae 380 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 103 111 7.2E-5 T 01-11-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFULGI_00005670 c1c63be25d959c5315f628d375d89dae 380 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 279 297 7.2E-5 T 01-11-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFULGI_00005670 c1c63be25d959c5315f628d375d89dae 380 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 291 8.3E-23 T 01-11-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFULGI_00005670 c1c63be25d959c5315f628d375d89dae 380 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 5.2E-5 T 01-11-2018 AFULGI_00005670 c1c63be25d959c5315f628d375d89dae 380 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 102 120 5.2E-5 T 01-11-2018 AFULGI_00014690 07b33ec59c53c041222e90eee6c3de12 280 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 10 275 3.6E-67 T 01-11-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 AFULGI_00014690 07b33ec59c53c041222e90eee6c3de12 280 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 87 272 4.4E-18 T 01-11-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFULGI_00014690 07b33ec59c53c041222e90eee6c3de12 280 SUPERFAMILY SSF161098 18 269 1.07E-30 T 01-11-2018 IPR035906 MetI-like superfamily AFULGI_00014690 07b33ec59c53c041222e90eee6c3de12 280 Gene3D G3DSA:1.10.3720.10 61 279 1.3E-26 T 01-11-2018 IPR035906 MetI-like superfamily AFULGI_00004230 df0d1d23c5f1f75f7f9c70f8ea214e09 246 SUPERFAMILY SSF51366 8 243 2.17E-24 T 01-11-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 AFULGI_00004230 df0d1d23c5f1f75f7f9c70f8ea214e09 246 Gene3D G3DSA:3.20.20.70 21 245 8.4E-6 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFULGI_00004230 df0d1d23c5f1f75f7f9c70f8ea214e09 246 ProDom PD011184 BTPA I PHOTOSYSTEM BIOGENESIS ASSEMBLY SGCQ TRIPHOSPHATASE NUCLEOSIDE PAE3553 ENZYME 23 189 1.0E-79 T 01-11-2018 IPR005137 Membrane complex biogenesis protein, BtpA family AFULGI_00004230 df0d1d23c5f1f75f7f9c70f8ea214e09 246 PIRSF PIRSF005956 1 246 6.2E-91 T 01-11-2018 IPR005137 Membrane complex biogenesis protein, BtpA family AFULGI_00004230 df0d1d23c5f1f75f7f9c70f8ea214e09 246 TIGRFAM TIGR00259 thylakoid_BtpA: membrane complex biogenesis protein, BtpA family 2 244 2.8E-116 T 01-11-2018 IPR005137 Membrane complex biogenesis protein, BtpA family AFULGI_00004230 df0d1d23c5f1f75f7f9c70f8ea214e09 246 Pfam PF03437 BtpA family 1 245 5.3E-112 T 01-11-2018 IPR005137 Membrane complex biogenesis protein, BtpA family AFULGI_00000180 e01e4cef9a98a9e6ff42eae2c2e73ea8 420 SUPERFAMILY SSF89796 6 418 1.44E-100 T 01-11-2018 IPR023606 CoA-transferase family III domain superfamily AFULGI_00000180 e01e4cef9a98a9e6ff42eae2c2e73ea8 420 Pfam PF02515 CoA-transferase family III 12 394 1.3E-110 T 01-11-2018 IPR003673 CoA-transferase family III GO:0003824 AFULGI_00000180 e01e4cef9a98a9e6ff42eae2c2e73ea8 420 Gene3D G3DSA:3.30.1540.10 241 345 5.5E-104 T 01-11-2018 AFULGI_00000180 e01e4cef9a98a9e6ff42eae2c2e73ea8 420 Gene3D G3DSA:3.40.50.10540 11 412 5.5E-104 T 01-11-2018 IPR023606 CoA-transferase family III domain superfamily AFULGI_00021960 fae74847bc71a1d76ac784663fbee181 227 TIGRFAM TIGR03875 RNA_lig_partner: RNA ligase partner, MJ_0950 family 4 210 1.7E-88 T 01-11-2018 IPR014856 PIN-domain ribonuclease AFULGI_00021960 fae74847bc71a1d76ac784663fbee181 227 Pfam PF08745 PINc domain ribonuclease 4 211 2.2E-90 T 01-11-2018 IPR014856 PIN-domain ribonuclease AFULGI_00021960 fae74847bc71a1d76ac784663fbee181 227 Hamap MF_01078 UPF0278 protein . 2 213 37.835 T 01-11-2018 IPR014856 PIN-domain ribonuclease AFULGI_00015320 d651435e7573261c92b8dde84f45919c 142 SUPERFAMILY SSF52374 2 135 7.88E-26 T 01-11-2018 AFULGI_00015320 d651435e7573261c92b8dde84f45919c 142 Pfam PF01467 Cytidylyltransferase-like 6 134 1.7E-25 T 01-11-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 AFULGI_00015320 d651435e7573261c92b8dde84f45919c 142 Gene3D G3DSA:3.40.50.620 2 121 1.2E-36 T 01-11-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFULGI_00015320 d651435e7573261c92b8dde84f45919c 142 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 4 67 4.4E-22 T 01-11-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 AFULGI_00015320 d651435e7573261c92b8dde84f45919c 142 Hamap MF_02115 FAD synthase [ribL]. 3 140 35.558 T 01-11-2018 IPR024902 FAD synthase RibL GO:0003919|GO:0006747|GO:0046444 KEGG: 00740+2.7.7.2|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AFULGI_00012540 3e1684e59ba54ec6c6b3dcbfbb00a761 195 Gene3D G3DSA:3.40.50.300 2 193 1.9E-5 T 01-11-2018 AFULGI_00011620 2754508502b8b1b107d2af86c606a2d7 118 Pfam PF00072 Response regulator receiver domain 4 109 2.2E-22 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFULGI_00011620 2754508502b8b1b107d2af86c606a2d7 118 SUPERFAMILY SSF52172 1 115 2.28E-32 T 01-11-2018 IPR011006 CheY-like superfamily AFULGI_00011620 2754508502b8b1b107d2af86c606a2d7 118 Gene3D G3DSA:3.40.50.2300 1 118 5.8E-31 T 01-11-2018 AFULGI_00011620 2754508502b8b1b107d2af86c606a2d7 118 SMART SM00448 2 110 1.3E-26 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFULGI_00003080 07082af6f1c6b8f197c0549fab815031 64 SUPERFAMILY SSF141694 1 57 2.07E-17 T 01-11-2018 AFULGI_00003080 07082af6f1c6b8f197c0549fab815031 64 Pfam PF01954 Protein of unknown function DUF104 1 55 4.4E-22 T 01-11-2018 IPR008203 Uncharacterised protein family UPF0165 AFULGI_00003080 07082af6f1c6b8f197c0549fab815031 64 Gene3D G3DSA:4.10.1150.10 1 63 1.4E-19 T 01-11-2018 IPR024069 AF2212-like domain superfamily AFULGI_00000030 6680b0a416066ec25e37952883b6e362 197 Pfam PF01402 Ribbon-helix-helix protein, copG family 6 43 8.1E-11 T 01-11-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 AFULGI_00001070 ad13dc57c485594c31d1e502a4e29ea7 534 SUPERFAMILY SSF55681 35 348 5.69E-38 T 01-11-2018 AFULGI_00001070 ad13dc57c485594c31d1e502a4e29ea7 534 Gene3D G3DSA:3.30.930.10 42 354 1.5E-74 T 01-11-2018 AFULGI_00001070 ad13dc57c485594c31d1e502a4e29ea7 534 Gene3D G3DSA:3.30.160.480 1 27 3.3E-20 T 01-11-2018 AFULGI_00001070 ad13dc57c485594c31d1e502a4e29ea7 534 Hamap MF_01674 O-phosphoserine--tRNA(Cys) ligase [sepS]. 1 534 292.212 T 01-11-2018 IPR005246 O-phosphoseryl-tRNA(Cys) ligase GO:0004812|GO:0005524|GO:0043039 KEGG: 00970+6.1.1.27|MetaCyc: PWY-6308 AFULGI_00001070 ad13dc57c485594c31d1e502a4e29ea7 534 Pfam PF01409 tRNA synthetases class II core domain (F) 107 351 6.4E-58 T 01-11-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 AFULGI_00001070 ad13dc57c485594c31d1e502a4e29ea7 534 TIGRFAM TIGR00470 sepS: O-phosphoserine--tRNA ligase 1 534 2.2E-302 T 01-11-2018 IPR005246 O-phosphoseryl-tRNA(Cys) ligase GO:0004812|GO:0005524|GO:0043039 KEGG: 00970+6.1.1.27|MetaCyc: PWY-6308 AFULGI_00001830 6d9e832ea4c447c26ef422daeafc5310 147 SUPERFAMILY SSF54637 2 146 1.89E-46 T 01-11-2018 IPR029069 HotDog domain superfamily AFULGI_00001830 6d9e832ea4c447c26ef422daeafc5310 147 Pfam PF01575 MaoC like domain 12 124 1.8E-37 T 01-11-2018 IPR002539 MaoC-like dehydratase domain AFULGI_00001830 6d9e832ea4c447c26ef422daeafc5310 147 Gene3D G3DSA:3.10.129.10 1 146 1.4E-51 T 01-11-2018 AFULGI_00026570 303fa4d4c47424eba22ba4cac52e1d83 114 Pfam PF00930 Dipeptidyl peptidase IV (DPP IV) N-terminal region 49 110 6.1E-6 T 01-11-2018 IPR002469 Dipeptidylpeptidase IV, N-terminal domain GO:0006508 AFULGI_00026570 303fa4d4c47424eba22ba4cac52e1d83 114 Gene3D G3DSA:2.120.10.30 17 113 8.1E-13 T 01-11-2018 IPR011042 Six-bladed beta-propeller, TolB-like AFULGI_00026570 303fa4d4c47424eba22ba4cac52e1d83 114 SUPERFAMILY SSF69304 47 108 2.88E-8 T 01-11-2018 AFULGI_00006810 7a38c6fd95908cb842bf30379c499186 75 SUPERFAMILY SSF53335 2 73 5.33E-15 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFULGI_00006810 7a38c6fd95908cb842bf30379c499186 75 Gene3D G3DSA:3.40.50.150 1 74 1.8E-16 T 01-11-2018 AFULGI_00006810 7a38c6fd95908cb842bf30379c499186 75 Pfam PF08241 Methyltransferase domain 2 73 6.9E-13 T 01-11-2018 IPR013216 Methyltransferase type 11 GO:0008168 AFULGI_00021140 21fbb6df76885d27fa7c2dfd8c0c54ef 289 Gene3D G3DSA:3.30.70.1900 165 288 3.3E-6 T 01-11-2018 AFULGI_00004170 65027822dad7ef03f65f3bf39e27e4ed 144 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 5 122 1.8E-13 T 01-11-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase AFULGI_00016890 ef360a51bff0b01ad7fa35688afdf113 893 SUPERFAMILY SSF52540 1 880 1.04E-34 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00016890 ef360a51bff0b01ad7fa35688afdf113 893 Gene3D G3DSA:3.40.50.300 646 890 1.1E-44 T 01-11-2018 AFULGI_00016890 ef360a51bff0b01ad7fa35688afdf113 893 Gene3D G3DSA:3.40.50.300 1 240 8.3E-48 T 01-11-2018 AFULGI_00016890 ef360a51bff0b01ad7fa35688afdf113 893 SMART SM00382 22 884 0.0052 T 01-11-2018 IPR003593 AAA+ ATPase domain AFULGI_00016890 ef360a51bff0b01ad7fa35688afdf113 893 Hamap MF_00449 DNA double-strand break repair Rad50 ATPase [rad50]. 1 891 13.389 T 01-11-2018 IPR022982 DNA double-strand break repair Rad50 ATPase, archaeal type AFULGI_00016890 ef360a51bff0b01ad7fa35688afdf113 893 Pfam PF13175 AAA ATPase domain 1 382 5.8E-14 T 01-11-2018 AFULGI_00016890 ef360a51bff0b01ad7fa35688afdf113 893 Pfam PF13175 AAA ATPase domain 557 866 9.5E-9 T 01-11-2018 AFULGI_00016890 ef360a51bff0b01ad7fa35688afdf113 893 Gene3D G3DSA:1.10.287.510 399 508 1.9E-16 T 01-11-2018 AFULGI_00016890 ef360a51bff0b01ad7fa35688afdf113 893 Pfam PF04423 Rad50 zinc hook motif 428 475 7.0E-8 T 01-11-2018 IPR013134 RAD50, zinc hook Reactome: R-HSA-2559586|Reactome: R-HSA-5685938|Reactome: R-HSA-5685939|Reactome: R-HSA-5685942|Reactome: R-HSA-5693548|Reactome: R-HSA-5693554|Reactome: R-HSA-5693565|Reactome: R-HSA-5693568|Reactome: R-HSA-5693571|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 AFULGI_00016890 ef360a51bff0b01ad7fa35688afdf113 893 SUPERFAMILY SSF75712 402 497 3.79E-15 T 01-11-2018 AFULGI_00003430 4c4646333b383f253f86afdd2dea72b9 125 SUPERFAMILY SSF49367 3 121 2.88E-41 T 01-11-2018 IPR036073 Desulfoferrodoxin, ferrous iron-binding domain superfamily GO:0005506|GO:0016491|GO:0055114 AFULGI_00003430 4c4646333b383f253f86afdd2dea72b9 125 TIGRFAM TIGR00332 neela_ferrous: desulfoferrodoxin ferrous iron-binding domain 5 125 6.2E-51 T 01-11-2018 IPR002742 Desulfoferrodoxin, ferrous iron-binding domain GO:0005506|GO:0016491|GO:0055114 AFULGI_00003430 4c4646333b383f253f86afdd2dea72b9 125 Gene3D G3DSA:2.60.40.730 1 125 9.7E-51 T 01-11-2018 IPR036073 Desulfoferrodoxin, ferrous iron-binding domain superfamily GO:0005506|GO:0016491|GO:0055114 AFULGI_00003430 4c4646333b383f253f86afdd2dea72b9 125 Pfam PF01880 Desulfoferrodoxin 7 118 1.0E-31 T 01-11-2018 IPR002742 Desulfoferrodoxin, ferrous iron-binding domain GO:0005506|GO:0016491|GO:0055114 AFULGI_00024720 2fb8376edc410b90760440a896a22ac7 179 Pfam PF00293 NUDIX domain 19 110 8.9E-17 T 01-11-2018 IPR000086 NUDIX hydrolase domain GO:0016787 AFULGI_00024720 2fb8376edc410b90760440a896a22ac7 179 SUPERFAMILY SSF55811 5 161 2.44E-24 T 01-11-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 AFULGI_00024720 2fb8376edc410b90760440a896a22ac7 179 ProSitePatterns PS00893 Nudix box signature. 55 76 - T 01-11-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 AFULGI_00024720 2fb8376edc410b90760440a896a22ac7 179 Gene3D G3DSA:3.90.79.10 7 163 4.3E-33 T 01-11-2018 AFULGI_00010760 fcfaee1cf576a5b9f6f0e8f1d00f14e4 178 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 2 177 29.944 T 01-11-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 AFULGI_00010760 fcfaee1cf576a5b9f6f0e8f1d00f14e4 178 SUPERFAMILY SSF54211 76 163 7.71E-22 T 01-11-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFULGI_00010760 fcfaee1cf576a5b9f6f0e8f1d00f14e4 178 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 25 159 2.8E-42 T 01-11-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 AFULGI_00010760 fcfaee1cf576a5b9f6f0e8f1d00f14e4 178 SUPERFAMILY SSF54211 3 70 1.39E-19 T 01-11-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFULGI_00010760 fcfaee1cf576a5b9f6f0e8f1d00f14e4 178 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 141 153 - T 01-11-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 AFULGI_00010760 fcfaee1cf576a5b9f6f0e8f1d00f14e4 178 Gene3D G3DSA:3.30.230.40 4 75 5.4E-26 T 01-11-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 AFULGI_00010760 fcfaee1cf576a5b9f6f0e8f1d00f14e4 178 Gene3D G3DSA:3.30.230.40 79 177 5.2E-24 T 01-11-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 AFULGI_00004790 beb128c52562d39430aaa1ccc729328a 187 Gene3D G3DSA:3.40.920.10 2 171 4.6E-44 T 01-11-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 AFULGI_00004790 beb128c52562d39430aaa1ccc729328a 187 SUPERFAMILY SSF53323 5 177 1.44E-30 T 01-11-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 AFULGI_00004790 beb128c52562d39430aaa1ccc729328a 187 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 13 166 5.9E-32 T 01-11-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 AFULGI_00007490 2df377dfdf89aa42c2751d1969295ba0 63 Gene3D G3DSA:3.30.429.10 2 63 1.5E-20 T 01-11-2018 IPR014347 Tautomerase/MIF superfamily AFULGI_00007490 2df377dfdf89aa42c2751d1969295ba0 63 TIGRFAM TIGR00013 taut: 4-oxalocrotonate tautomerase family enzyme 1 62 4.1E-23 T 01-11-2018 IPR018191 4-oxalocrotonate tautomerase, Pseudomonas-type GO:0006725|GO:0016853 AFULGI_00007490 2df377dfdf89aa42c2751d1969295ba0 63 Pfam PF01361 Tautomerase enzyme 2 60 1.4E-15 T 01-11-2018 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 AFULGI_00007490 2df377dfdf89aa42c2751d1969295ba0 63 SUPERFAMILY SSF55331 5 60 2.26E-10 T 01-11-2018 IPR014347 Tautomerase/MIF superfamily AFULGI_00016300 213580271acc0733047e43c196ebfc92 141 SUPERFAMILY SSF81593 14 134 3.14E-6 T 01-11-2018 AFULGI_00016300 213580271acc0733047e43c196ebfc92 141 Pfam PF01934 Protein of unknown function DUF86 18 133 1.9E-33 T 01-11-2018 IPR008201 Protein of unknown function DUF86 AFULGI_00016300 213580271acc0733047e43c196ebfc92 141 Gene3D G3DSA:1.20.120.580 2 141 1.2E-24 T 01-11-2018 IPR037038 Bsu32300-like superfamily AFULGI_00025420 cc5ac273bba053cb5b95a2fd13cf1efc 77 PIRSF PIRSF037031 1 77 1.5E-30 T 01-11-2018 IPR005243 Redox-active disulphide protein 2 AFULGI_00025420 cc5ac273bba053cb5b95a2fd13cf1efc 77 Pfam PF13192 Thioredoxin domain 1 76 8.2E-24 T 01-11-2018 IPR012336 Thioredoxin-like fold AFULGI_00025420 cc5ac273bba053cb5b95a2fd13cf1efc 77 Gene3D G3DSA:3.40.30.10 1 75 2.6E-25 T 01-11-2018 AFULGI_00025420 cc5ac273bba053cb5b95a2fd13cf1efc 77 SUPERFAMILY SSF52833 1 76 6.81E-18 T 01-11-2018 IPR036249 Thioredoxin-like superfamily AFULGI_00025420 cc5ac273bba053cb5b95a2fd13cf1efc 77 TIGRFAM TIGR00412 redox_disulf_2: redox-active disulfide protein 2 1 77 5.3E-41 T 01-11-2018 IPR005243 Redox-active disulphide protein 2 AFULGI_00021010 a845a9e149e32b900f15eb29442ad43b 126 Gene3D G3DSA:1.10.10.10 2 116 4.0E-34 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00021010 a845a9e149e32b900f15eb29442ad43b 126 SUPERFAMILY SSF46785 17 106 2.9E-14 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00021010 a845a9e149e32b900f15eb29442ad43b 126 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 13 87 7.8E-18 T 01-11-2018 IPR002831 Transcription regulator TrmB, N-terminal AFULGI_00011660 ccd317a05892671b80d0cdd856486e72 89 Gene3D G3DSA:3.30.110.20 1 88 1.1E-36 T 01-11-2018 IPR036882 Alba-like domain superfamily GO:0003676 AFULGI_00011660 ccd317a05892671b80d0cdd856486e72 89 SUPERFAMILY SSF82704 2 88 1.02E-25 T 01-11-2018 IPR036882 Alba-like domain superfamily GO:0003676 AFULGI_00011660 ccd317a05892671b80d0cdd856486e72 89 Pfam PF01918 Alba 4 67 5.3E-21 T 01-11-2018 IPR002775 DNA/RNA-binding protein Alba-like GO:0003676 AFULGI_00011660 ccd317a05892671b80d0cdd856486e72 89 PIRSF PIRSF028732 1 89 1.9E-40 T 01-11-2018 IPR013795 DNA/RNA-binding protein Alba GO:0003677|GO:0003723|GO:0005737 AFULGI_00011660 ccd317a05892671b80d0cdd856486e72 89 ProDom PD010497 ALBA DNA-BINDING DNA/RNA-BINDING RNA-BINDING ACETYLATION 3D-STRUCTURE DNA CONDENSATION AF1 SSO10B 8 89 2.0E-40 T 01-11-2018 AFULGI_00011660 ccd317a05892671b80d0cdd856486e72 89 TIGRFAM TIGR00285 TIGR00285: DNA-binding protein Alba 3 88 6.1E-49 T 01-11-2018 IPR013795 DNA/RNA-binding protein Alba GO:0003677|GO:0003723|GO:0005737 AFULGI_00011660 ccd317a05892671b80d0cdd856486e72 89 Hamap MF_01122 DNA/RNA-binding protein Alba [albA]. 1 88 26.377 T 01-11-2018 IPR013795 DNA/RNA-binding protein Alba GO:0003677|GO:0003723|GO:0005737 AFULGI_00008790 f9a2509e551ea0ccc71a73c6397569d0 324 Pfam PF04055 Radical SAM superfamily 12 177 5.2E-13 T 01-11-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFULGI_00008790 f9a2509e551ea0ccc71a73c6397569d0 324 Hamap MF_01611 FO synthase subunit 1 [cofG]. 4 314 52.615 T 01-11-2018 IPR019939 CofG family GO:0009108|GO:0016765|GO:0051539 KEGG: 00680+2.5.1.77 AFULGI_00008790 f9a2509e551ea0ccc71a73c6397569d0 324 SMART SM00729 8 223 4.6E-15 T 01-11-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 AFULGI_00008790 f9a2509e551ea0ccc71a73c6397569d0 324 Gene3D G3DSA:3.20.20.70 2 265 1.9E-43 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFULGI_00008790 f9a2509e551ea0ccc71a73c6397569d0 324 SUPERFAMILY SSF102114 9 281 1.02E-41 T 01-11-2018 AFULGI_00008790 f9a2509e551ea0ccc71a73c6397569d0 324 TIGRFAM TIGR03550 F420_cofG: 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofG subunit 5 312 6.0E-135 T 01-11-2018 IPR019939 CofG family GO:0009108|GO:0016765|GO:0051539 KEGG: 00680+2.5.1.77 AFULGI_00020630 f757b2da6e1d15ba1a21cddcf2f6a423 177 SUPERFAMILY SSF88697 2 98 4.22E-17 T 01-11-2018 IPR015947 PUA-like superfamily AFULGI_00020630 f757b2da6e1d15ba1a21cddcf2f6a423 177 Pfam PF04266 ASCH domain 4 89 8.0E-15 T 01-11-2018 IPR007374 ASCH domain AFULGI_00020630 f757b2da6e1d15ba1a21cddcf2f6a423 177 SMART SM01022 4 98 2.8E-20 T 01-11-2018 IPR007374 ASCH domain AFULGI_00026630 538352b9c33d1c23ce49226bb39f3276 836 Gene3D G3DSA:3.10.620.30 177 338 2.6E-20 T 01-11-2018 AFULGI_00026630 538352b9c33d1c23ce49226bb39f3276 836 SUPERFAMILY SSF54001 200 412 1.14E-23 T 01-11-2018 IPR038765 Papain-like cysteine peptidase superfamily AFULGI_00026630 538352b9c33d1c23ce49226bb39f3276 836 SMART SM00460 248 315 9.5E-21 T 01-11-2018 IPR002931 Transglutaminase-like AFULGI_00026630 538352b9c33d1c23ce49226bb39f3276 836 Pfam PF01841 Transglutaminase-like superfamily 206 313 8.2E-25 T 01-11-2018 IPR002931 Transglutaminase-like AFULGI_00022800 34eac3a00a9824521366108ff4eb69d5 543 Gene3D G3DSA:3.40.50.1220 185 337 6.3E-34 T 01-11-2018 AFULGI_00022800 34eac3a00a9824521366108ff4eb69d5 543 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 192 311 9.1E-27 T 01-11-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 AFULGI_00022800 34eac3a00a9824521366108ff4eb69d5 543 SUPERFAMILY SSF52518 1 173 1.64E-44 T 01-11-2018 IPR029061 Thiamin diphosphate-binding fold AFULGI_00022800 34eac3a00a9824521366108ff4eb69d5 543 SUPERFAMILY SSF52467 187 359 7.12E-37 T 01-11-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily AFULGI_00022800 34eac3a00a9824521366108ff4eb69d5 543 SUPERFAMILY SSF52518 352 534 5.14E-42 T 01-11-2018 IPR029061 Thiamin diphosphate-binding fold AFULGI_00022800 34eac3a00a9824521366108ff4eb69d5 543 Gene3D G3DSA:3.40.50.970 338 534 9.1E-48 T 01-11-2018 AFULGI_00022800 34eac3a00a9824521366108ff4eb69d5 543 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 375 524 2.3E-28 T 01-11-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 AFULGI_00022800 34eac3a00a9824521366108ff4eb69d5 543 Gene3D G3DSA:3.40.50.970 1 175 6.7E-53 T 01-11-2018 AFULGI_00022800 34eac3a00a9824521366108ff4eb69d5 543 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 410 429 - T 01-11-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 AFULGI_00022800 34eac3a00a9824521366108ff4eb69d5 543 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 1 167 2.4E-50 T 01-11-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 AFULGI_00013130 f8c76a600ca634739f41e2fdae942e03 182 Gene3D G3DSA:3.40.50.1950 1 182 9.3E-68 T 01-11-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 AFULGI_00013130 f8c76a600ca634739f41e2fdae942e03 182 Pfam PF02441 Flavoprotein 1 163 2.3E-25 T 01-11-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 AFULGI_00013130 f8c76a600ca634739f41e2fdae942e03 182 Hamap MF_01984 Flavin prenyltransferase UbiX [ubiX]. 1 182 33.367 T 01-11-2018 IPR004507 Flavin prenyltransferase UbiX-like AFULGI_00013130 f8c76a600ca634739f41e2fdae942e03 182 SUPERFAMILY SSF52507 1 179 3.66E-55 T 01-11-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 AFULGI_00013130 f8c76a600ca634739f41e2fdae942e03 182 TIGRFAM TIGR00421 ubiX_pad: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases 2 181 9.0E-88 T 01-11-2018 IPR004507 Flavin prenyltransferase UbiX-like AFULGI_00022170 92478deb1b5c4d1a6de2ade089e2d4ad 391 Pfam PF06050 2-hydroxyglutaryl-CoA dehydratase, D-component 35 390 2.2E-68 T 01-11-2018 IPR010327 FldB/FldC dehydratase alpha/beta subunit AFULGI_00022170 92478deb1b5c4d1a6de2ade089e2d4ad 391 Gene3D G3DSA:3.40.50.11890 26 169 5.0E-8 T 01-11-2018 AFULGI_00022170 92478deb1b5c4d1a6de2ade089e2d4ad 391 Gene3D G3DSA:3.40.50.11900 270 391 9.7E-11 T 01-11-2018 AFULGI_00022170 92478deb1b5c4d1a6de2ade089e2d4ad 391 Gene3D G3DSA:1.20.1270.370 25 205 5.0E-8 T 01-11-2018 AFULGI_00009190 d63292d4aa58ee3bfbbb6523ffdd9bf7 115 Pfam PF06397 Desulfoferrodoxin, N-terminal domain 1 27 8.3E-15 T 01-11-2018 IPR004462 Desulforodoxin domain GO:0005506 AFULGI_00009190 d63292d4aa58ee3bfbbb6523ffdd9bf7 115 SUPERFAMILY SSF57802 2 27 2.35E-8 T 01-11-2018 AFULGI_00009190 d63292d4aa58ee3bfbbb6523ffdd9bf7 115 Gene3D G3DSA:2.60.40.730 30 115 4.5E-32 T 01-11-2018 IPR036073 Desulfoferrodoxin, ferrous iron-binding domain superfamily GO:0005506|GO:0016491|GO:0055114 AFULGI_00009190 d63292d4aa58ee3bfbbb6523ffdd9bf7 115 SUPERFAMILY SSF49367 30 114 1.83E-33 T 01-11-2018 IPR036073 Desulfoferrodoxin, ferrous iron-binding domain superfamily GO:0005506|GO:0016491|GO:0055114 AFULGI_00009190 d63292d4aa58ee3bfbbb6523ffdd9bf7 115 TIGRFAM TIGR00319 desulf_FeS4: desulfoferrodoxin FeS4 iron-binding domain 1 24 2.5E-14 T 01-11-2018 IPR004462 Desulforodoxin domain GO:0005506 AFULGI_00009190 d63292d4aa58ee3bfbbb6523ffdd9bf7 115 TIGRFAM TIGR00320 dfx_rbo: desulfoferrodoxin 1 114 4.0E-67 T 01-11-2018 IPR004793 Desulfoferrodoxin GO:0005506|GO:0019430 AFULGI_00009190 d63292d4aa58ee3bfbbb6523ffdd9bf7 115 Pfam PF01880 Desulfoferrodoxin 32 114 5.9E-24 T 01-11-2018 IPR002742 Desulfoferrodoxin, ferrous iron-binding domain GO:0005506|GO:0016491|GO:0055114 AFULGI_00009190 d63292d4aa58ee3bfbbb6523ffdd9bf7 115 TIGRFAM TIGR00332 neela_ferrous: desulfoferrodoxin ferrous iron-binding domain 30 114 2.3E-35 T 01-11-2018 IPR002742 Desulfoferrodoxin, ferrous iron-binding domain GO:0005506|GO:0016491|GO:0055114 AFULGI_00009190 d63292d4aa58ee3bfbbb6523ffdd9bf7 115 Gene3D G3DSA:2.20.28.100 1 28 1.5E-12 T 01-11-2018 IPR038094 Desulforodoxin domain superfamily AFULGI_00004850 ea7378b9fa48c34d553bc595389866ed 409 Gene3D G3DSA:1.10.8.60 333 402 2.3E-14 T 01-11-2018 AFULGI_00004850 ea7378b9fa48c34d553bc595389866ed 409 SUPERFAMILY SSF52540 157 398 1.22E-51 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00004850 ea7378b9fa48c34d553bc595389866ed 409 ProSitePatterns PS00674 AAA-protein family signature. 302 321 - T 01-11-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 AFULGI_00004850 ea7378b9fa48c34d553bc595389866ed 409 Gene3D G3DSA:3.40.50.300 150 331 4.5E-47 T 01-11-2018 AFULGI_00004850 ea7378b9fa48c34d553bc595389866ed 409 SMART SM00382 197 332 4.3E-15 T 01-11-2018 IPR003593 AAA+ ATPase domain AFULGI_00004850 ea7378b9fa48c34d553bc595389866ed 409 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 201 329 1.8E-37 T 01-11-2018 IPR003959 ATPase, AAA-type, core GO:0005524 AFULGI_00007700 983e2ad0be411be139621a45e9b898cf 187 Pfam PF14470 Bacterial PH domain 12 105 5.3E-24 T 01-11-2018 IPR039519 YokE-like, PH domain AFULGI_00007700 983e2ad0be411be139621a45e9b898cf 187 Pfam PF09851 Short C-terminal domain 157 184 9.4E-11 T 01-11-2018 IPR018649 SHOCT domain AFULGI_00017350 f61c73a54d3f49ef8b1a4893fe3f9b87 53 Pfam PF06745 KaiC 3 50 1.3E-15 T 01-11-2018 IPR014774 KaiC-like domain AFULGI_00017350 f61c73a54d3f49ef8b1a4893fe3f9b87 53 Gene3D G3DSA:3.40.50.300 1 52 1.5E-15 T 01-11-2018 AFULGI_00017350 f61c73a54d3f49ef8b1a4893fe3f9b87 53 SUPERFAMILY SSF52540 2 45 8.46E-13 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00000240 54619aa3f122b45f6f3bd36af55b8aac 266 Pfam PF11495 Archaeal transcriptional regulator TrmB 137 264 3.6E-9 T 01-11-2018 IPR021586 Transcription regulator TrmB, C-terminal AFULGI_00000240 54619aa3f122b45f6f3bd36af55b8aac 266 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 28 92 5.0E-17 T 01-11-2018 IPR002831 Transcription regulator TrmB, N-terminal AFULGI_00000240 54619aa3f122b45f6f3bd36af55b8aac 266 Gene3D G3DSA:1.10.10.10 18 117 2.3E-21 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00000240 54619aa3f122b45f6f3bd36af55b8aac 266 SUPERFAMILY SSF46785 19 87 6.2E-10 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00021240 4764932cfb0233d5d577ab61f67de7a8 312 Pfam PF04467 Protein of unknown function (DUF483) 110 247 4.4E-39 T 01-11-2018 IPR007556 Protein of unknown function DUF483 AFULGI_00004300 4764932cfb0233d5d577ab61f67de7a8 312 Pfam PF04467 Protein of unknown function (DUF483) 110 247 4.4E-39 T 01-11-2018 IPR007556 Protein of unknown function DUF483 AFULGI_00021220 79fa6cfddf9280eec2c095c107ee3ed9 981 Pfam PF12469 CRISPR-associated protein 226 341 1.3E-30 T 01-11-2018 IPR024615 CRISPR-associated protein Cmr2, N-terminal AFULGI_00021220 79fa6cfddf9280eec2c095c107ee3ed9 981 Gene3D G3DSA:3.30.70.2220 195 408 2.8E-51 T 01-11-2018 IPR038242 Cmr2, N-terminal domain superfamily AFULGI_00021220 79fa6cfddf9280eec2c095c107ee3ed9 981 TIGRFAM TIGR02577 cas_TM1794_Cmr2: CRISPR-associated protein Cas10/Cmr2, subtype III-B 225 829 4.3E-192 T 01-11-2018 IPR013407 CRISPR-associated protein Cmr2 AFULGI_00023050 7a00603f5e8111ffbbe6d7721aff9a4d 627 Gene3D G3DSA:2.30.310.10 4 146 1.4E-30 T 01-11-2018 AFULGI_00023050 7a00603f5e8111ffbbe6d7721aff9a4d 627 Pfam PF05670 Domain of unknown function (DUF814) 427 526 1.1E-25 T 01-11-2018 IPR008532 Domain of unknown function DUF814 AFULGI_00023050 7a00603f5e8111ffbbe6d7721aff9a4d 627 SUPERFAMILY SSF46946 163 204 1.44E-7 T 01-11-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 AFULGI_00023050 7a00603f5e8111ffbbe6d7721aff9a4d 627 Pfam PF05833 Fibronectin-binding protein A N-terminus (FbpA) 6 407 6.5E-77 T 01-11-2018 AFULGI_00002980 c94efdcd1c8928197d077c1bc92ba1e2 324 Gene3D G3DSA:1.20.5.100 200 231 5.9E-17 T 01-11-2018 AFULGI_00002980 c94efdcd1c8928197d077c1bc92ba1e2 324 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 201 293 4.5E-40 T 01-11-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AFULGI_00002980 c94efdcd1c8928197d077c1bc92ba1e2 324 Gene3D G3DSA:3.40.50.720 1 198 5.7E-70 T 01-11-2018 AFULGI_00002980 c94efdcd1c8928197d077c1bc92ba1e2 324 Gene3D G3DSA:3.40.50.720 232 323 3.3E-26 T 01-11-2018 AFULGI_00002980 c94efdcd1c8928197d077c1bc92ba1e2 324 SUPERFAMILY SSF51735 2 191 2.66E-48 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily AFULGI_00002980 c94efdcd1c8928197d077c1bc92ba1e2 324 SUPERFAMILY SSF48179 201 295 4.76E-34 T 01-11-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AFULGI_00002980 c94efdcd1c8928197d077c1bc92ba1e2 324 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2 187 1.1E-63 T 01-11-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AFULGI_00002980 c94efdcd1c8928197d077c1bc92ba1e2 324 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 2 312 4.3E-115 T 01-11-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 AFULGI_00009060 348d23a4b7eff3a778a27a465d8c1c72 94 Gene3D G3DSA:1.10.287.1080 1 77 4.1E-23 T 01-11-2018 AFULGI_00009060 348d23a4b7eff3a778a27a465d8c1c72 94 SUPERFAMILY SSF101386 2 84 2.94E-19 T 01-11-2018 AFULGI_00009060 348d23a4b7eff3a778a27a465d8c1c72 94 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 23 75 7.2E-10 T 01-11-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core AFULGI_00006370 739d19b581cf49f80966011f0a281ad2 166 Pfam PF13610 DDE domain 78 155 1.4E-10 T 01-11-2018 IPR032874 DDE domain AFULGI_00000250 fff9b3349705099d5be50e53828c40fe 94 Pfam PF08734 GYD domain 3 90 4.2E-31 T 01-11-2018 IPR014845 Protein GYD/TTHA1554 AFULGI_00017290 e197ae52f5aa73d93562be9bc44d99ba 128 SUPERFAMILY SSF55021 61 125 2.71E-18 T 01-11-2018 AFULGI_00017290 e197ae52f5aa73d93562be9bc44d99ba 128 Gene3D G3DSA:3.30.2130.10 1 122 3.3E-28 T 01-11-2018 AFULGI_00017290 e197ae52f5aa73d93562be9bc44d99ba 128 PIRSF PIRSF008459 1 128 1.9E-58 T 01-11-2018 IPR016540 Uncharacterised conserved protein UCP008459 AFULGI_00017290 e197ae52f5aa73d93562be9bc44d99ba 128 Pfam PF13840 ACT domain 57 119 4.2E-21 T 01-11-2018 IPR027795 CASTOR, ACT domain AFULGI_00022490 8f464a2cdbb8a4d52f85532e6fc1b153 216 SUPERFAMILY SSF46785 172 213 1.16E-5 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00022490 8f464a2cdbb8a4d52f85532e6fc1b153 216 Gene3D G3DSA:1.10.10.10 133 215 7.7E-6 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00022810 a5be435a8304b220c195365fba8dcc26 307 Gene3D G3DSA:3.40.50.720 1 304 2.3E-66 T 01-11-2018 AFULGI_00022810 a5be435a8304b220c195365fba8dcc26 307 SUPERFAMILY SSF51735 1 302 2.22E-54 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily AFULGI_00022810 a5be435a8304b220c195365fba8dcc26 307 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 224 2.1E-30 T 01-11-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 AFULGI_00011650 7d1ae5116942a056af9da8b154650519 332 TIGRFAM TIGR03555 F420_mer: 5,10-methylenetetrahydromethanopterin reductase 3 329 2.1E-177 T 01-11-2018 IPR019946 5,10-methylenetetrahydromethanopterin reductase GO:0018537|GO:0055114 KEGG: 00680+1.5.98.2|MetaCyc: PWY-7784 AFULGI_00011650 7d1ae5116942a056af9da8b154650519 332 Hamap MF_01091 5,10-methylenetetrahydromethanopterin reductase [mer]. 1 332 177.2 T 01-11-2018 IPR019946 5,10-methylenetetrahydromethanopterin reductase GO:0018537|GO:0055114 KEGG: 00680+1.5.98.2|MetaCyc: PWY-7784 AFULGI_00011650 7d1ae5116942a056af9da8b154650519 332 Pfam PF00296 Luciferase-like monooxygenase 15 305 3.1E-69 T 01-11-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 AFULGI_00011650 7d1ae5116942a056af9da8b154650519 332 Gene3D G3DSA:3.20.20.30 1 330 1.5E-116 T 01-11-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFULGI_00011650 7d1ae5116942a056af9da8b154650519 332 SUPERFAMILY SSF51679 1 331 5.23E-73 T 01-11-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFULGI_00009810 ce61647fbaf5894641c68c7d70115649 212 Gene3D G3DSA:3.40.50.720 1 212 2.0E-66 T 01-11-2018 AFULGI_00009810 ce61647fbaf5894641c68c7d70115649 212 TIGRFAM TIGR01915 npdG: NADPH-dependent F420 reductase 1 211 2.1E-67 T 01-11-2018 IPR010185 NADPH-dependent F420 reductase GO:0006740|GO:0016651|GO:0050661|GO:0055114|GO:0070967 AFULGI_00009810 ce61647fbaf5894641c68c7d70115649 212 SUPERFAMILY SSF51735 1 207 1.33E-52 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily AFULGI_00009810 ce61647fbaf5894641c68c7d70115649 212 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 2 99 1.3E-23 T 01-11-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal AFULGI_00011640 aea8d2801aa62f4ac534283fc10d9f0f 108 Gene3D G3DSA:2.30.130.30 1 95 5.9E-27 T 01-11-2018 AFULGI_00011640 aea8d2801aa62f4ac534283fc10d9f0f 108 SMART SM01022 1 93 6.0E-4 T 01-11-2018 IPR007374 ASCH domain AFULGI_00011640 aea8d2801aa62f4ac534283fc10d9f0f 108 Pfam PF04266 ASCH domain 2 91 1.5E-10 T 01-11-2018 IPR007374 ASCH domain AFULGI_00011640 aea8d2801aa62f4ac534283fc10d9f0f 108 SUPERFAMILY SSF88697 1 104 4.97E-26 T 01-11-2018 IPR015947 PUA-like superfamily AFULGI_00004360 e889473dbab43f9fa82c2fd1a5f8e992 366 Gene3D G3DSA:3.40.50.1980 172 364 3.5E-74 T 01-11-2018 AFULGI_00004360 e889473dbab43f9fa82c2fd1a5f8e992 366 Pfam PF01497 Periplasmic binding protein 50 296 1.0E-29 T 01-11-2018 IPR002491 ABC transporter periplasmic binding domain AFULGI_00004360 e889473dbab43f9fa82c2fd1a5f8e992 366 Gene3D G3DSA:3.40.50.1980 24 171 8.2E-58 T 01-11-2018 AFULGI_00004360 e889473dbab43f9fa82c2fd1a5f8e992 366 SUPERFAMILY SSF53807 34 352 1.69E-53 T 01-11-2018 AFULGI_00011520 13118189f3b1d2fdb18f588d52e38353 212 Pfam PF01917 Archaebacterial flagellin 14 199 6.3E-48 T 01-11-2018 IPR002774 Flagellin, archaea GO:0005198|GO:0006928 AFULGI_00011520 13118189f3b1d2fdb18f588d52e38353 212 TIGRFAM TIGR02537 arch_flag_Nterm: archaeal flagellin N-terminal-like domain 13 34 9.5E-6 T 01-11-2018 IPR013373 Flagellin/pilin, N-terminal AFULGI_00014190 b52bee016984f372180fa40ebd0cb98c 188 Gene3D G3DSA:3.40.50.300 1 185 2.5E-23 T 01-11-2018 AFULGI_00014190 b52bee016984f372180fa40ebd0cb98c 188 Pfam PF02223 Thymidylate kinase 6 176 5.8E-37 T 01-11-2018 IPR039430 Thymidylate kinase-like domain KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 AFULGI_00014190 b52bee016984f372180fa40ebd0cb98c 188 SUPERFAMILY SSF52540 1 184 3.9E-20 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00017840 426270cc70f5e4edf66101c326ca93b6 116 SUPERFAMILY SSF47819 2 111 1.09E-24 T 01-11-2018 IPR010997 HRDC-like superfamily GO:0000166|GO:0003824|GO:0044237 AFULGI_00017840 426270cc70f5e4edf66101c326ca93b6 116 Gene3D G3DSA:1.10.150.80 51 116 1.6E-23 T 01-11-2018 AFULGI_00017840 426270cc70f5e4edf66101c326ca93b6 116 PIRSF PIRSF005053 1 116 4.0E-32 T 01-11-2018 IPR010924 DNA-directed RNA polymerase subunit F (Rpo4) AFULGI_00017840 426270cc70f5e4edf66101c326ca93b6 116 Gene3D G3DSA:1.10.287.420 2 50 2.3E-7 T 01-11-2018 AFULGI_00017840 426270cc70f5e4edf66101c326ca93b6 116 Pfam PF03874 RNA polymerase Rpb4 15 115 1.7E-7 T 01-11-2018 IPR005574 RNA polymerase subunit RPB4/RPC9 GO:0006352|GO:0030880 AFULGI_00011600 e0d8591821a0f3d42c79eec07c016cff 304 Gene3D G3DSA:3.30.1490.350 124 164 8.3E-64 T 01-11-2018 AFULGI_00011600 e0d8591821a0f3d42c79eec07c016cff 304 PIRSF PIRSF016766 1 304 2.5E-101 T 01-11-2018 IPR024710 Tyramine--L-glutamate ligase KEGG: 00680+6.3.4.24|MetaCyc: PWY-5254 AFULGI_00011600 e0d8591821a0f3d42c79eec07c016cff 304 Pfam PF02655 ATP-grasp domain 108 251 1.3E-43 T 01-11-2018 IPR003806 ATP-grasp fold, DUF201-type GO:0005524|GO:0046872 AFULGI_00011600 e0d8591821a0f3d42c79eec07c016cff 304 Gene3D G3DSA:3.40.50.11770 1 97 2.7E-53 T 01-11-2018 AFULGI_00011600 e0d8591821a0f3d42c79eec07c016cff 304 SUPERFAMILY SSF56059 122 267 9.12E-19 T 01-11-2018 AFULGI_00011600 e0d8591821a0f3d42c79eec07c016cff 304 Gene3D G3DSA:3.30.470.20 103 265 8.3E-64 T 01-11-2018 AFULGI_00021560 f5e708e09193c6c9a2f2941563a1af8c 350 Pfam PF00535 Glycosyl transferase family 2 4 85 2.0E-9 T 01-11-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 AFULGI_00021560 f5e708e09193c6c9a2f2941563a1af8c 350 SUPERFAMILY SSF53448 4 262 1.13E-29 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFULGI_00021560 f5e708e09193c6c9a2f2941563a1af8c 350 Gene3D G3DSA:3.90.550.10 3 188 2.4E-18 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFULGI_00021560 f5e708e09193c6c9a2f2941563a1af8c 350 Pfam PF13632 Glycosyl transferase family group 2 104 258 3.3E-14 T 01-11-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 AFULGI_00003410 27dc2860cf5742f49c60557320a52d80 150 SUPERFAMILY SSF57802 112 145 9.97E-11 T 01-11-2018 AFULGI_00003410 27dc2860cf5742f49c60557320a52d80 150 Gene3D G3DSA:2.20.28.10 110 146 2.7E-14 T 01-11-2018 AFULGI_00004180 21de6c9321b6b819e73e15dbcd954fba 336 Pfam PF08735 Putative pyruvate format-lyase activating enzyme (DUF1786) 60 308 4.0E-77 T 01-11-2018 IPR014846 Protein of unknown function DUF1786, putative pyruvate format-lyase activating enzyme AFULGI_00004180 21de6c9321b6b819e73e15dbcd954fba 336 PIRSF PIRSF029129 6 336 1.3E-127 T 01-11-2018 IPR014846 Protein of unknown function DUF1786, putative pyruvate format-lyase activating enzyme AFULGI_00022600 21dd110943f5341d4e9a412fd7ca86c4 489 SUPERFAMILY SSF161070 3 480 6.15E-144 T 01-11-2018 IPR037272 Sodium:neurotransmitter symporter superfamily GO:0005328 AFULGI_00022600 21dd110943f5341d4e9a412fd7ca86c4 489 ProSitePatterns PS00610 Sodium:neurotransmitter symporter family signature 1. 27 41 - T 01-11-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 AFULGI_00022600 21dd110943f5341d4e9a412fd7ca86c4 489 Pfam PF00209 Sodium:neurotransmitter symporter family 3 121 3.1E-36 T 01-11-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 AFULGI_00022600 21dd110943f5341d4e9a412fd7ca86c4 489 Pfam PF00209 Sodium:neurotransmitter symporter family 126 481 5.8E-76 T 01-11-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 AFULGI_00022600 21dd110943f5341d4e9a412fd7ca86c4 489 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 40 59 3.3E-27 T 01-11-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 AFULGI_00022600 21dd110943f5341d4e9a412fd7ca86c4 489 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 85 111 3.3E-27 T 01-11-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 AFULGI_00022600 21dd110943f5341d4e9a412fd7ca86c4 489 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 312 331 3.3E-27 T 01-11-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 AFULGI_00022600 21dd110943f5341d4e9a412fd7ca86c4 489 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 429 449 3.3E-27 T 01-11-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 AFULGI_00022600 21dd110943f5341d4e9a412fd7ca86c4 489 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 11 32 3.3E-27 T 01-11-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 AFULGI_00022600 21dd110943f5341d4e9a412fd7ca86c4 489 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 389 409 3.3E-27 T 01-11-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 AFULGI_00018360 6b834c9f86a50469713ea5227902bcb4 112 Pfam PF05168 HEPN domain 1 111 1.7E-26 T 01-11-2018 IPR007842 HEPN domain AFULGI_00018360 6b834c9f86a50469713ea5227902bcb4 112 SUPERFAMILY SSF81593 3 111 1.77E-22 T 01-11-2018 AFULGI_00018360 6b834c9f86a50469713ea5227902bcb4 112 SMART SM00748 5 108 8.2E-32 T 01-11-2018 IPR007842 HEPN domain AFULGI_00018360 6b834c9f86a50469713ea5227902bcb4 112 Gene3D G3DSA:1.20.120.330 1 112 7.2E-20 T 01-11-2018 AFULGI_00009200 68b8fdc661a591aa122f89febd33bf5c 173 Gene3D G3DSA:1.20.1260.10 1 173 1.0E-60 T 01-11-2018 IPR012347 Ferritin-like AFULGI_00009200 68b8fdc661a591aa122f89febd33bf5c 173 SUPERFAMILY SSF47240 4 161 7.47E-62 T 01-11-2018 IPR009078 Ferritin-like superfamily AFULGI_00009200 68b8fdc661a591aa122f89febd33bf5c 173 Pfam PF00210 Ferritin-like domain 10 145 6.7E-44 T 01-11-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 AFULGI_00014310 d22eb428181a83b12e8798e3902d0ea5 183 Hamap MF_01510 GMP synthase [glutamine-hydrolyzing] subunit A [guaAA]. 2 183 45.237 T 01-11-2018 IPR023686 GMP synthase (glutamine-hydrolyzing) subunit A GO:0003922 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 AFULGI_00014310 d22eb428181a83b12e8798e3902d0ea5 183 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 3 182 7.9E-76 T 01-11-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 AFULGI_00014310 d22eb428181a83b12e8798e3902d0ea5 183 Gene3D G3DSA:3.40.50.880 1 183 1.9E-55 T 01-11-2018 IPR029062 Class I glutamine amidotransferase-like AFULGI_00014310 d22eb428181a83b12e8798e3902d0ea5 183 SUPERFAMILY SSF52317 1 182 1.19E-51 T 01-11-2018 IPR029062 Class I glutamine amidotransferase-like AFULGI_00014310 d22eb428181a83b12e8798e3902d0ea5 183 PRINTS PR00096 Glutamine amidotransferase superfamily signature 69 80 1.1E-7 T 01-11-2018 AFULGI_00014310 d22eb428181a83b12e8798e3902d0ea5 183 PRINTS PR00096 Glutamine amidotransferase superfamily signature 157 170 1.1E-7 T 01-11-2018 AFULGI_00014310 d22eb428181a83b12e8798e3902d0ea5 183 PRINTS PR00096 Glutamine amidotransferase superfamily signature 45 54 1.1E-7 T 01-11-2018 AFULGI_00014310 d22eb428181a83b12e8798e3902d0ea5 183 Pfam PF00117 Glutamine amidotransferase class-I 5 178 1.9E-40 T 01-11-2018 IPR017926 Glutamine amidotransferase AFULGI_00014310 d22eb428181a83b12e8798e3902d0ea5 183 PRINTS PR00097 Anthranilate synthase component II signature 157 170 2.6E-8 T 01-11-2018 AFULGI_00014310 d22eb428181a83b12e8798e3902d0ea5 183 PRINTS PR00097 Anthranilate synthase component II signature 3 17 2.6E-8 T 01-11-2018 AFULGI_00014310 d22eb428181a83b12e8798e3902d0ea5 183 PRINTS PR00097 Anthranilate synthase component II signature 69 80 2.6E-8 T 01-11-2018 AFULGI_00014310 d22eb428181a83b12e8798e3902d0ea5 183 PRINTS PR00097 Anthranilate synthase component II signature 45 54 2.6E-8 T 01-11-2018 AFULGI_00015500 c935ec91e3d757b3facaaf2886b55136 220 Pfam PF03358 NADPH-dependent FMN reductase 1 146 8.9E-26 T 01-11-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 AFULGI_00015500 c935ec91e3d757b3facaaf2886b55136 220 SUPERFAMILY SSF52218 1 177 2.79E-47 T 01-11-2018 IPR029039 Flavoprotein-like superfamily AFULGI_00015500 c935ec91e3d757b3facaaf2886b55136 220 Gene3D G3DSA:3.40.50.360 2 220 3.0E-62 T 01-11-2018 IPR029039 Flavoprotein-like superfamily AFULGI_00021050 d1d605e66a020732c7fdcbd53c0ecb6c 334 Pfam PF02754 Cysteine-rich domain 222 307 4.8E-11 T 01-11-2018 IPR004017 Cysteine-rich domain AFULGI_00021050 d1d605e66a020732c7fdcbd53c0ecb6c 334 SUPERFAMILY SSF54862 5 70 6.45E-5 T 01-11-2018 AFULGI_00021050 d1d605e66a020732c7fdcbd53c0ecb6c 334 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 51 62 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFULGI_00013630 9a9f980a926e12e870e5308cb0f09b4f 251 Pfam PF12840 Helix-turn-helix domain 166 220 2.5E-9 T 01-11-2018 AFULGI_00013630 9a9f980a926e12e870e5308cb0f09b4f 251 PIRSF PIRSF018357 1 247 8.1E-85 T 01-11-2018 IPR016723 Transcription regulator, ArsR, predicted AFULGI_00013630 9a9f980a926e12e870e5308cb0f09b4f 251 Gene3D G3DSA:1.10.10.10 143 236 6.4E-16 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00013630 9a9f980a926e12e870e5308cb0f09b4f 251 SMART SM00418 163 241 1.0E-16 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFULGI_00013630 9a9f980a926e12e870e5308cb0f09b4f 251 SUPERFAMILY SSF46785 148 228 9.72E-15 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00025370 b891dbf7a70f2f004110a8ce81ccdf4f 397 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 8 118 4.9E-37 T 01-11-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 AFULGI_00025370 b891dbf7a70f2f004110a8ce81ccdf4f 397 Gene3D G3DSA:2.40.110.10 121 235 1.7E-49 T 01-11-2018 AFULGI_00025370 b891dbf7a70f2f004110a8ce81ccdf4f 397 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 219 3.9E-32 T 01-11-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 AFULGI_00025370 b891dbf7a70f2f004110a8ce81ccdf4f 397 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 339 358 - T 01-11-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 AFULGI_00025370 b891dbf7a70f2f004110a8ce81ccdf4f 397 SUPERFAMILY SSF56645 3 242 1.83E-90 T 01-11-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 AFULGI_00025370 b891dbf7a70f2f004110a8ce81ccdf4f 397 Gene3D G3DSA:1.10.540.10 1 120 1.0E-42 T 01-11-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 AFULGI_00025370 b891dbf7a70f2f004110a8ce81ccdf4f 397 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 231 381 9.7E-51 T 01-11-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AFULGI_00025370 b891dbf7a70f2f004110a8ce81ccdf4f 397 SUPERFAMILY SSF47203 229 384 1.5E-52 T 01-11-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 AFULGI_00025370 b891dbf7a70f2f004110a8ce81ccdf4f 397 Gene3D G3DSA:1.20.140.10 236 387 1.4E-48 T 01-11-2018 AFULGI_00025370 b891dbf7a70f2f004110a8ce81ccdf4f 397 PIRSF PIRSF016578 5 389 1.2E-18 T 01-11-2018 AFULGI_00006590 0a5054e5a4c9c7fd834d80f264457b4e 145 SUPERFAMILY SSF54909 62 142 7.37E-11 T 01-11-2018 IPR011008 Dimeric alpha-beta barrel AFULGI_00006590 0a5054e5a4c9c7fd834d80f264457b4e 145 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 1.6E-13 T 01-11-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFULGI_00006590 0a5054e5a4c9c7fd834d80f264457b4e 145 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 1.6E-13 T 01-11-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFULGI_00006590 0a5054e5a4c9c7fd834d80f264457b4e 145 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 1.6E-13 T 01-11-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFULGI_00006590 0a5054e5a4c9c7fd834d80f264457b4e 145 SUPERFAMILY SSF46785 1 57 1.22E-14 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00006590 0a5054e5a4c9c7fd834d80f264457b4e 145 Pfam PF01037 Lrp/AsnC ligand binding domain 72 132 2.6E-9 T 01-11-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain AFULGI_00006590 0a5054e5a4c9c7fd834d80f264457b4e 145 SMART SM00344 1 104 8.4E-44 T 01-11-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 AFULGI_00006590 0a5054e5a4c9c7fd834d80f264457b4e 145 Pfam PF13412 Winged helix-turn-helix DNA-binding 1 48 5.9E-15 T 01-11-2018 AFULGI_00006590 0a5054e5a4c9c7fd834d80f264457b4e 145 Gene3D G3DSA:1.10.10.10 1 53 1.1E-18 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00006590 0a5054e5a4c9c7fd834d80f264457b4e 145 Gene3D G3DSA:3.30.70.920 54 142 2.6E-13 T 01-11-2018 AFULGI_00003680 9b921021c14ede02c6bbe31bc6d6a43a 397 SUPERFAMILY SSF103473 4 396 4.45E-67 T 01-11-2018 IPR036259 MFS transporter superfamily AFULGI_00003680 9b921021c14ede02c6bbe31bc6d6a43a 397 Gene3D G3DSA:1.20.1250.20 1 397 3.8E-68 T 01-11-2018 AFULGI_00003680 9b921021c14ede02c6bbe31bc6d6a43a 397 Pfam PF07690 Major Facilitator Superfamily 11 349 6.7E-44 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFULGI_00009000 80451b37b18319ada085ac0013b18eff 165 Hamap MF_00796 Nucleoside-triphosphatase . 1 163 26.8 T 01-11-2018 IPR004948 Nucleoside-triphosphatase, THEP1 type GO:0098519 KEGG: 00230+3.6.1.15|KEGG: 00730+3.6.1.15|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210 AFULGI_00009000 80451b37b18319ada085ac0013b18eff 165 Pfam PF03266 NTPase 2 159 5.2E-53 T 01-11-2018 IPR004948 Nucleoside-triphosphatase, THEP1 type GO:0098519 KEGG: 00230+3.6.1.15|KEGG: 00730+3.6.1.15|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210 AFULGI_00009000 80451b37b18319ada085ac0013b18eff 165 SUPERFAMILY SSF52540 3 163 1.02E-16 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00009000 80451b37b18319ada085ac0013b18eff 165 SMART SM00382 1 150 0.0068 T 01-11-2018 IPR003593 AAA+ ATPase domain AFULGI_00009000 80451b37b18319ada085ac0013b18eff 165 Gene3D G3DSA:3.40.50.300 1 164 2.2E-45 T 01-11-2018 AFULGI_00009420 8d80b3f23081406f1cd5e4d8610ce307 89 Pfam PF04981 NMD3 family 6 83 2.0E-8 T 01-11-2018 IPR007064 Nmd3, N-terminal AFULGI_00012420 fe7ac5b6e2bd9017840dff545fab8951 156 Pfam PF01066 CDP-alcohol phosphatidyltransferase 9 51 1.2E-6 T 01-11-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 AFULGI_00012420 fe7ac5b6e2bd9017840dff545fab8951 156 Gene3D G3DSA:1.20.120.1760 1 156 1.3E-38 T 01-11-2018 AFULGI_00012420 fe7ac5b6e2bd9017840dff545fab8951 156 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 29 51 - T 01-11-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 AFULGI_00007890 31494d93e87cc3187f44f3bf925b19f9 184 Gene3D G3DSA:3.40.1180.10 64 184 6.3E-25 T 01-11-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 AFULGI_00007890 31494d93e87cc3187f44f3bf925b19f9 184 SUPERFAMILY SSF64005 13 178 4.05E-29 T 01-11-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 AFULGI_00007890 31494d93e87cc3187f44f3bf925b19f9 184 Pfam PF01255 Putative undecaprenyl diphosphate synthase 85 183 4.9E-18 T 01-11-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 AFULGI_00012080 994e5a36a001697653f2123e1fe83009 103 Gene3D G3DSA:3.30.310.190 1 98 1.1E-29 T 01-11-2018 AFULGI_00012080 994e5a36a001697653f2123e1fe83009 103 PIRSF PIRSF022080 1 102 8.9E-42 T 01-11-2018 IPR016800 Uncharacterised conserved protein UCP022080 AFULGI_00008880 9a32607abef5c7cd70d7cc2c9215f177 64 Pfam PF10049 Protein of unknown function (DUF2283) 2 45 2.3E-10 T 01-11-2018 IPR019270 Protein of unknown function DUF2283 AFULGI_00010030 166ec86363767d7a943a87b5384c8f6c 296 Gene3D G3DSA:1.10.8.240 32 119 2.9E-98 T 01-11-2018 AFULGI_00010030 166ec86363767d7a943a87b5384c8f6c 296 Gene3D G3DSA:3.40.50.10680 5 269 2.9E-98 T 01-11-2018 AFULGI_00010030 166ec86363767d7a943a87b5384c8f6c 296 Hamap MF_01257 2-phospho-L-lactate transferase [cofD]. 1 296 109.624 T 01-11-2018 IPR010115 2-phospho-L-lactate transferase GO:0000287|GO:0016780|GO:0051188 KEGG: 00680+2.7.8.28|MetaCyc: PWY-5198 AFULGI_00010030 166ec86363767d7a943a87b5384c8f6c 296 TIGRFAM TIGR01819 F420_cofD: 2-phospho-L-lactate transferase 2 290 1.1E-137 T 01-11-2018 IPR010115 2-phospho-L-lactate transferase GO:0000287|GO:0016780|GO:0051188 KEGG: 00680+2.7.8.28|MetaCyc: PWY-5198 AFULGI_00010030 166ec86363767d7a943a87b5384c8f6c 296 SUPERFAMILY SSF142338 2 293 2.75E-86 T 01-11-2018 AFULGI_00010030 166ec86363767d7a943a87b5384c8f6c 296 Pfam PF01933 Uncharacterised protein family UPF0052 3 275 5.9E-50 T 01-11-2018 IPR002882 LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 AFULGI_00001280 b622e86fd0d5f8b41ff2dc0a223ae4c3 194 SUPERFAMILY SSF55469 8 191 9.95E-46 T 01-11-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 AFULGI_00001280 b622e86fd0d5f8b41ff2dc0a223ae4c3 194 Gene3D G3DSA:3.40.109.10 6 192 2.3E-51 T 01-11-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 AFULGI_00001280 b622e86fd0d5f8b41ff2dc0a223ae4c3 194 Pfam PF00881 Nitroreductase family 11 172 9.5E-39 T 01-11-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 AFULGI_00017500 677d5fdc422b3822781286f9e0ccb274 276 SMART SM00849 20 187 9.1E-17 T 01-11-2018 IPR001279 Metallo-beta-lactamase AFULGI_00017500 677d5fdc422b3822781286f9e0ccb274 276 SUPERFAMILY SSF56281 2 274 4.76E-25 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFULGI_00017500 677d5fdc422b3822781286f9e0ccb274 276 Gene3D G3DSA:3.60.15.10 1 218 4.2E-20 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFULGI_00026750 b8ad7528fcada83ed0603695fc2e0d0d 363 SUPERFAMILY SSF51679 1 345 2.62E-64 T 01-11-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFULGI_00026750 b8ad7528fcada83ed0603695fc2e0d0d 363 Pfam PF00296 Luciferase-like monooxygenase 1 334 1.3E-87 T 01-11-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 AFULGI_00026750 b8ad7528fcada83ed0603695fc2e0d0d 363 Gene3D G3DSA:3.20.20.30 1 363 6.0E-79 T 01-11-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFULGI_00020710 d3a3fff3f2c0d2dafd3a5152f61f7bb1 169 Pfam PF00440 Bacterial regulatory proteins, tetR family 8 54 1.1E-15 T 01-11-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFULGI_00020710 d3a3fff3f2c0d2dafd3a5152f61f7bb1 169 SUPERFAMILY SSF46689 7 67 4.05E-15 T 01-11-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFULGI_00020710 d3a3fff3f2c0d2dafd3a5152f61f7bb1 169 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 52 3.3E-7 T 01-11-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFULGI_00020710 d3a3fff3f2c0d2dafd3a5152f61f7bb1 169 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 8 21 3.3E-7 T 01-11-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFULGI_00020710 d3a3fff3f2c0d2dafd3a5152f61f7bb1 169 Gene3D G3DSA:1.10.357.10 1 169 3.4E-66 T 01-11-2018 AFULGI_00012640 e441e8767b09eb4d2a3949c686aa727b 101 Pfam PF01990 ATP synthase (F/14-kDa) subunit 5 93 1.3E-17 T 01-11-2018 IPR008218 ATPase, V1 complex, subunit F GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 AFULGI_00012640 e441e8767b09eb4d2a3949c686aa727b 101 Gene3D G3DSA:3.40.50.10580 1 94 1.2E-28 T 01-11-2018 IPR036906 ATPase, V1 complex, subunit F superfamily GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 AFULGI_00012640 e441e8767b09eb4d2a3949c686aa727b 101 SUPERFAMILY SSF159468 4 100 9.42E-23 T 01-11-2018 IPR036906 ATPase, V1 complex, subunit F superfamily GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 AFULGI_00012640 e441e8767b09eb4d2a3949c686aa727b 101 Hamap MF_00312 V-type ATP synthase subunit F [atpF]. 2 100 26.068 T 01-11-2018 IPR022944 ATPase, V1 complex, subunit F, bacterial/archaeal AFULGI_00008740 019b3706e49ca4cd1a4dc69bb492f007 232 Gene3D G3DSA:3.20.20.410 2 228 1.1E-40 T 01-11-2018 IPR036520 UPF0759 superfamily AFULGI_00008740 019b3706e49ca4cd1a4dc69bb492f007 232 SUPERFAMILY SSF117396 2 226 1.29E-43 T 01-11-2018 IPR036520 UPF0759 superfamily AFULGI_00008740 019b3706e49ca4cd1a4dc69bb492f007 232 Pfam PF01904 Protein of unknown function DUF72 14 223 3.7E-33 T 01-11-2018 IPR002763 Protein of unknown function DUF72 AFULGI_00020280 c99c6a015069ccc3b2f6fce7d96bc927 245 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 5 232 2.0E-55 T 01-11-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 AFULGI_00020280 c99c6a015069ccc3b2f6fce7d96bc927 245 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 1 244 6.3E-79 T 01-11-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 AFULGI_00020280 c99c6a015069ccc3b2f6fce7d96bc927 245 SUPERFAMILY SSF102705 1 241 2.49E-64 T 01-11-2018 IPR036069 GTP cyclohydrolase 1 type 2/Nif3 superfamily AFULGI_00020280 c99c6a015069ccc3b2f6fce7d96bc927 245 Gene3D G3DSA:3.40.1390.30 96 216 4.7E-74 T 01-11-2018 AFULGI_00020280 c99c6a015069ccc3b2f6fce7d96bc927 245 Gene3D G3DSA:3.40.1390.30 14 230 4.7E-74 T 01-11-2018 AFULGI_00009900 be3ef8320f7732c64e5031ebf742259d 403 TIGRFAM TIGR01910 DapE-ArgE: peptidase, ArgE/DapE family 15 393 2.0E-78 T 01-11-2018 IPR010182 N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase/Succinyl-diaminopimelate desuccinylase AFULGI_00009900 be3ef8320f7732c64e5031ebf742259d 403 Gene3D G3DSA:3.30.70.360 197 319 7.0E-70 T 01-11-2018 AFULGI_00009900 be3ef8320f7732c64e5031ebf742259d 403 Pfam PF01546 Peptidase family M20/M25/M40 86 396 1.7E-32 T 01-11-2018 IPR002933 Peptidase M20 GO:0016787 AFULGI_00009900 be3ef8320f7732c64e5031ebf742259d 403 SUPERFAMILY SSF53187 2 397 9.71E-53 T 01-11-2018 AFULGI_00009900 be3ef8320f7732c64e5031ebf742259d 403 SUPERFAMILY SSF55031 199 311 4.19E-14 T 01-11-2018 IPR036264 Bacterial exopeptidase dimerisation domain AFULGI_00009900 be3ef8320f7732c64e5031ebf742259d 403 Gene3D G3DSA:3.40.630.10 19 388 7.0E-70 T 01-11-2018 AFULGI_00009900 be3ef8320f7732c64e5031ebf742259d 403 Pfam PF07687 Peptidase dimerisation domain 193 297 1.2E-14 T 01-11-2018 IPR011650 Peptidase M20, dimerisation domain AFULGI_00012070 4fb734770402dc19a516d0b215ddcbb4 183 Pfam PF09920 Uncharacterized protein conserved in archaea (DUF2150) 2 177 6.2E-52 T 01-11-2018 IPR014518 Uncharacterised conserved protein UCP022079 AFULGI_00012070 4fb734770402dc19a516d0b215ddcbb4 183 PIRSF PIRSF022079 1 183 5.7E-86 T 01-11-2018 IPR014518 Uncharacterised conserved protein UCP022079 AFULGI_00001010 7872dd5b317396948dda7af66e180304 138 PIRSF PIRSF016702 1 138 4.5E-50 T 01-11-2018 IPR025707 Predicted DNA-binding protein with PD1-like DNA-binding motif AFULGI_00001010 7872dd5b317396948dda7af66e180304 138 Pfam PF03479 Domain of unknown function (DUF296) 12 118 2.5E-21 T 01-11-2018 IPR005175 PPC domain AFULGI_00001010 7872dd5b317396948dda7af66e180304 138 Gene3D G3DSA:3.30.1330.80 1 138 3.2E-58 T 01-11-2018 AFULGI_00001010 7872dd5b317396948dda7af66e180304 138 SUPERFAMILY SSF117856 1 138 9.16E-41 T 01-11-2018 AFULGI_00015680 2e995bb0cc31dd19e37fd05b082c91dc 659 Pfam PF09334 tRNA synthetases class I (M) 3 388 3.6E-152 T 01-11-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFULGI_00015680 2e995bb0cc31dd19e37fd05b082c91dc 659 Gene3D G3DSA:2.40.50.140 548 659 3.6E-40 T 01-11-2018 AFULGI_00015680 2e995bb0cc31dd19e37fd05b082c91dc 659 Gene3D G3DSA:2.20.28.20 136 170 2.0E-144 T 01-11-2018 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 AFULGI_00015680 2e995bb0cc31dd19e37fd05b082c91dc 659 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 528 659 9.3E-51 T 01-11-2018 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 AFULGI_00015680 2e995bb0cc31dd19e37fd05b082c91dc 659 Pfam PF01588 Putative tRNA binding domain 565 657 5.5E-31 T 01-11-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 AFULGI_00015680 2e995bb0cc31dd19e37fd05b082c91dc 659 SUPERFAMILY SSF52374 3 374 1.51E-107 T 01-11-2018 AFULGI_00015680 2e995bb0cc31dd19e37fd05b082c91dc 659 SUPERFAMILY SSF50249 558 658 9.3E-34 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold AFULGI_00015680 2e995bb0cc31dd19e37fd05b082c91dc 659 Gene3D G3DSA:1.10.730.10 371 538 1.1E-31 T 01-11-2018 AFULGI_00015680 2e995bb0cc31dd19e37fd05b082c91dc 659 SUPERFAMILY SSF57770 136 170 1.31E-5 T 01-11-2018 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 AFULGI_00015680 2e995bb0cc31dd19e37fd05b082c91dc 659 SUPERFAMILY SSF47323 379 572 3.36E-34 T 01-11-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFULGI_00015680 2e995bb0cc31dd19e37fd05b082c91dc 659 Hamap MF_00098 Methionine--tRNA ligase [metG]. 1 536 39.364 T 01-11-2018 IPR023458 Methionine-tRNA ligase, type 1 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 AFULGI_00015680 2e995bb0cc31dd19e37fd05b082c91dc 659 Pfam PF08264 Anticodon-binding domain of tRNA 404 552 2.1E-10 T 01-11-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 AFULGI_00015680 2e995bb0cc31dd19e37fd05b082c91dc 659 PRINTS PR01041 Methionyl-tRNA synthetase signature 36 50 8.3E-26 T 01-11-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 AFULGI_00015680 2e995bb0cc31dd19e37fd05b082c91dc 659 PRINTS PR01041 Methionyl-tRNA synthetase signature 375 386 8.3E-26 T 01-11-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 AFULGI_00015680 2e995bb0cc31dd19e37fd05b082c91dc 659 PRINTS PR01041 Methionyl-tRNA synthetase signature 4 17 8.3E-26 T 01-11-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 AFULGI_00015680 2e995bb0cc31dd19e37fd05b082c91dc 659 PRINTS PR01041 Methionyl-tRNA synthetase signature 84 95 8.3E-26 T 01-11-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 AFULGI_00015680 2e995bb0cc31dd19e37fd05b082c91dc 659 PRINTS PR01041 Methionyl-tRNA synthetase signature 281 296 8.3E-26 T 01-11-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 AFULGI_00015680 2e995bb0cc31dd19e37fd05b082c91dc 659 PRINTS PR01041 Methionyl-tRNA synthetase signature 243 254 8.3E-26 T 01-11-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 AFULGI_00015680 2e995bb0cc31dd19e37fd05b082c91dc 659 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 3 526 1.7E-201 T 01-11-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 AFULGI_00015680 2e995bb0cc31dd19e37fd05b082c91dc 659 Gene3D G3DSA:3.40.50.620 3 370 2.0E-144 T 01-11-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFULGI_00010750 2f75761d506c996bbd68457bd27a81a0 231 SUPERFAMILY SSF52540 15 218 8.94E-54 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00010750 2f75761d506c996bbd68457bd27a81a0 231 Gene3D G3DSA:3.40.50.300 4 230 5.4E-60 T 01-11-2018 AFULGI_00010750 2f75761d506c996bbd68457bd27a81a0 231 SMART SM00382 39 220 2.0E-11 T 01-11-2018 IPR003593 AAA+ ATPase domain AFULGI_00010750 2f75761d506c996bbd68457bd27a81a0 231 Pfam PF00005 ABC transporter 31 168 1.1E-29 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFULGI_00005840 0ef2845ba3e34b0c040805a7cbb46b0e 429 Pfam PF00589 Phage integrase family 160 329 7.6E-12 T 01-11-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 AFULGI_00005840 0ef2845ba3e34b0c040805a7cbb46b0e 429 Gene3D G3DSA:1.10.443.10 150 331 2.4E-18 T 01-11-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 AFULGI_00005840 0ef2845ba3e34b0c040805a7cbb46b0e 429 SUPERFAMILY SSF56349 59 337 2.83E-27 T 01-11-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 AFULGI_00004240 210bf9fa1997cd9eba1e32e929e96462 78 Hamap MF_01245 UPF0248 protein . 10 78 19.689 T 01-11-2018 IPR007547 Uncharacterised protein family UPF0248 AFULGI_00004240 210bf9fa1997cd9eba1e32e929e96462 78 Pfam PF04457 Protein of unknown function (DUF504) 26 77 1.6E-16 T 01-11-2018 IPR007547 Uncharacterised protein family UPF0248 AFULGI_00009930 b9c2462cb00168c789688e245b45f047 406 SUPERFAMILY SSF103473 4 403 1.57E-68 T 01-11-2018 IPR036259 MFS transporter superfamily AFULGI_00009930 b9c2462cb00168c789688e245b45f047 406 Pfam PF07690 Major Facilitator Superfamily 16 275 1.0E-35 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFULGI_00009930 b9c2462cb00168c789688e245b45f047 406 Gene3D G3DSA:1.20.1250.20 203 406 5.1E-29 T 01-11-2018 AFULGI_00009930 b9c2462cb00168c789688e245b45f047 406 Gene3D G3DSA:1.20.1250.20 2 192 9.1E-37 T 01-11-2018 AFULGI_00009930 b9c2462cb00168c789688e245b45f047 406 PIRSF PIRSF002808 1 406 3.4E-34 T 01-11-2018 IPR000849 Sugar phosphate transporter GO:0016021|GO:0022857|GO:0055085 AFULGI_00009410 5b0f08c6cf9c1d2e92e0c45d8de1efc6 314 Pfam PF14811 Protein of unknown function TPD sequence-motif 105 231 2.8E-37 T 01-11-2018 IPR029404 Protein of unknown function with TPD sequence-motif AFULGI_00022540 56843664c7b50df907a4473dc6ad5f4d 253 SUPERFAMILY SSF54534 2 145 1.46E-37 T 01-11-2018 AFULGI_00022540 56843664c7b50df907a4473dc6ad5f4d 253 Gene3D G3DSA:2.40.10.330 89 129 8.9E-47 T 01-11-2018 AFULGI_00022540 56843664c7b50df907a4473dc6ad5f4d 253 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 3 89 9.1E-12 T 01-11-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain AFULGI_00022540 56843664c7b50df907a4473dc6ad5f4d 253 Gene3D G3DSA:3.10.50.40 5 143 8.9E-47 T 01-11-2018 AFULGI_00006770 63dd6b7b9adbb7b4022c704337e78076 445 Gene3D G3DSA:3.40.50.2000 231 426 5.8E-30 T 01-11-2018 AFULGI_00006770 63dd6b7b9adbb7b4022c704337e78076 445 SUPERFAMILY SSF53756 4 444 1.2E-38 T 01-11-2018 AFULGI_00006770 63dd6b7b9adbb7b4022c704337e78076 445 Gene3D G3DSA:3.40.50.2000 110 433 5.8E-30 T 01-11-2018 AFULGI_00006770 63dd6b7b9adbb7b4022c704337e78076 445 Pfam PF00534 Glycosyl transferases group 1 254 407 2.7E-24 T 01-11-2018 IPR001296 Glycosyl transferase, family 1 AFULGI_00020600 9afb13c386169384c30ccb09fe4f456f 75 Pfam PF14947 Winged helix-turn-helix 14 74 3.8E-6 T 01-11-2018 IPR038723 ArnR1-like, winged helix-turn-helix domain AFULGI_00020600 9afb13c386169384c30ccb09fe4f456f 75 SUPERFAMILY SSF46785 10 73 1.31E-10 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00020600 9afb13c386169384c30ccb09fe4f456f 75 Gene3D G3DSA:1.10.10.10 2 72 2.0E-8 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00019910 5a060a092083fbc6503d50d44e59b29d 179 Hamap MF_01117 CDP-archaeol synthase [carS]. 12 179 27.929 T 01-11-2018 IPR002726 CDP-archaeol synthase, archaea KEGG: 00564+2.7.7.67|MetaCyc: PWY-6349 AFULGI_00019910 5a060a092083fbc6503d50d44e59b29d 179 Pfam PF01864 CDP-archaeol synthase 1 179 5.1E-88 T 01-11-2018 IPR032690 CDP-archaeol synthase KEGG: 00564+2.7.7.67|MetaCyc: PWY-6349 AFULGI_00006180 3bb5edae2ce1119a11cf56cd7c938ac4 364 SUPERFAMILY SSF56300 1 275 2.85E-47 T 01-11-2018 AFULGI_00006180 3bb5edae2ce1119a11cf56cd7c938ac4 364 Hamap MF_02044 DNA double-strand break repair protein Mre11 [mre11]. 1 362 21.838 T 01-11-2018 IPR032885 DNA double-strand break repair protein Mre11, archaea-type GO:0006302 AFULGI_00006180 3bb5edae2ce1119a11cf56cd7c938ac4 364 Pfam PF00149 Calcineurin-like phosphoesterase 1 187 5.8E-12 T 01-11-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 AFULGI_00006180 3bb5edae2ce1119a11cf56cd7c938ac4 364 Gene3D G3DSA:3.60.21.10 1 242 4.3E-52 T 01-11-2018 IPR029052 Metallo-dependent phosphatase-like AFULGI_00009400 59a3dd8e3041f41bc907871eb6ce8a3f 286 Gene3D G3DSA:3.90.226.10 65 257 3.2E-22 T 01-11-2018 AFULGI_00009400 59a3dd8e3041f41bc907871eb6ce8a3f 286 SUPERFAMILY SSF52096 61 243 6.22E-28 T 01-11-2018 IPR029045 ClpP/crotonase-like domain superfamily AFULGI_00009400 59a3dd8e3041f41bc907871eb6ce8a3f 286 Pfam PF01972 Serine dehydrogenase proteinase 3 281 1.2E-164 T 01-11-2018 IPR002825 Peptidase S49, serine-peptidase prokaryotes GO:0016021 AFULGI_00022450 8768f4e1a019456eb482bccef4618063 312 Gene3D G3DSA:3.40.50.1980 19 168 1.1E-26 T 01-11-2018 AFULGI_00022450 8768f4e1a019456eb482bccef4618063 312 SUPERFAMILY SSF53807 13 276 1.96E-44 T 01-11-2018 AFULGI_00022450 8768f4e1a019456eb482bccef4618063 312 Pfam PF01297 Zinc-uptake complex component A periplasmic 23 275 5.4E-31 T 01-11-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 AFULGI_00005810 3437c8f68d417a3b19a729530a10cfbc 148 Gene3D G3DSA:3.40.50.980 34 137 1.7E-13 T 01-11-2018 AFULGI_00005810 3437c8f68d417a3b19a729530a10cfbc 148 Pfam PF00501 AMP-binding enzyme 35 139 3.0E-6 T 01-11-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFULGI_00005810 3437c8f68d417a3b19a729530a10cfbc 148 SUPERFAMILY SSF56801 35 142 3.92E-11 T 01-11-2018 AFULGI_00001800 65e993e219b1aea782dc4e30cd812b9f 106 SUPERFAMILY SSF47240 2 98 2.88E-6 T 01-11-2018 IPR009078 Ferritin-like superfamily AFULGI_00007930 82ebdcb6507de670a73eee020da49afe 117 Pfam PF00085 Thioredoxin 27 102 4.3E-11 T 01-11-2018 IPR013766 Thioredoxin domain GO:0045454 AFULGI_00007930 82ebdcb6507de670a73eee020da49afe 117 SUPERFAMILY SSF52833 29 108 5.9E-14 T 01-11-2018 IPR036249 Thioredoxin-like superfamily AFULGI_00007930 82ebdcb6507de670a73eee020da49afe 117 Gene3D G3DSA:3.40.30.10 25 117 5.8E-15 T 01-11-2018 AFULGI_00016830 9de6dd67c8b874560bce1bc8370f4bf2 215 Pfam PF04893 Yip1 domain 4 203 2.2E-27 T 01-11-2018 IPR006977 Yip1 domain GO:0016020 AFULGI_00017580 d7600d42eedd3bf4efea6d98b5b54da6 343 Gene3D G3DSA:3.40.50.720 5 338 3.1E-142 T 01-11-2018 AFULGI_00017580 d7600d42eedd3bf4efea6d98b5b54da6 343 PIRSF PIRSF000148 2 343 1.6E-109 T 01-11-2018 AFULGI_00017580 d7600d42eedd3bf4efea6d98b5b54da6 343 Gene3D G3DSA:3.30.360.10 149 320 3.1E-142 T 01-11-2018 AFULGI_00017580 d7600d42eedd3bf4efea6d98b5b54da6 343 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 157 323 1.9E-45 T 01-11-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 AFULGI_00017580 d7600d42eedd3bf4efea6d98b5b54da6 343 TIGRFAM TIGR00978 asd_EA: aspartate-semialdehyde dehydrogenase 5 338 1.5E-146 T 01-11-2018 IPR005676 Aspartate-semialdehyde dehydrogenase, peptidoglycan lacking GO:0050661|GO:0055114 AFULGI_00017580 d7600d42eedd3bf4efea6d98b5b54da6 343 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 5 126 7.8E-36 T 01-11-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 AFULGI_00017580 d7600d42eedd3bf4efea6d98b5b54da6 343 SUPERFAMILY SSF51735 3 174 4.73E-47 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily AFULGI_00017580 d7600d42eedd3bf4efea6d98b5b54da6 343 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 2 338 35.289 T 01-11-2018 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 AFULGI_00017580 d7600d42eedd3bf4efea6d98b5b54da6 343 ProSitePatterns PS01103 Aspartate-semialdehyde dehydrogenase signature. 227 241 - T 01-11-2018 IPR000319 Aspartate-semialdehyde dehydrogenase, conserved site GO:0004073|GO:0006520|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 AFULGI_00017580 d7600d42eedd3bf4efea6d98b5b54da6 343 SUPERFAMILY SSF55347 146 325 3.82E-46 T 01-11-2018 AFULGI_00017580 d7600d42eedd3bf4efea6d98b5b54da6 343 SMART SM00859 4 129 4.6E-41 T 01-11-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 AFULGI_00007780 4d9103cfba83dbaeeb67996d3fffeeb8 263 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 5 212 1.3E-23 T 01-11-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain AFULGI_00007780 4d9103cfba83dbaeeb67996d3fffeeb8 263 Gene3D G3DSA:3.40.50.300 1 233 4.4E-69 T 01-11-2018 AFULGI_00007780 4d9103cfba83dbaeeb67996d3fffeeb8 263 PIRSF PIRSF003092 1 263 2.2E-63 T 01-11-2018 IPR025501 ATP binding protein MinD AFULGI_00007780 4d9103cfba83dbaeeb67996d3fffeeb8 263 SUPERFAMILY SSF52540 1 234 1.42E-57 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00007780 4d9103cfba83dbaeeb67996d3fffeeb8 263 TIGRFAM TIGR01969 minD_arch: cell division ATPase MinD 3 258 8.3E-121 T 01-11-2018 IPR010224 ATP binding protein MinD, archaea AFULGI_00013090 d8fa12fdbdd29b657c4a81f96688f060 313 Pfam PF05853 beta-keto acid cleavage enzyme 7 305 3.4E-103 T 01-11-2018 IPR008567 3-keto-5-aminohexanoate cleavage enzyme GO:0016740|GO:0019475 KEGG: 00310+2.3.1.247 AFULGI_00013090 d8fa12fdbdd29b657c4a81f96688f060 313 Gene3D G3DSA:3.20.20.70 1 313 2.3E-140 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFULGI_00013090 d8fa12fdbdd29b657c4a81f96688f060 313 SUPERFAMILY SSF102114 24 143 1.33E-5 T 01-11-2018 AFULGI_00016670 1d3a5ebd6cc57d76c0d8a426cce1aefc 412 Gene3D G3DSA:3.10.620.30 106 275 1.2E-16 T 01-11-2018 AFULGI_00016670 1d3a5ebd6cc57d76c0d8a426cce1aefc 412 Pfam PF01841 Transglutaminase-like superfamily 170 224 7.6E-10 T 01-11-2018 IPR002931 Transglutaminase-like AFULGI_00016670 1d3a5ebd6cc57d76c0d8a426cce1aefc 412 SUPERFAMILY SSF54001 166 263 3.83E-20 T 01-11-2018 IPR038765 Papain-like cysteine peptidase superfamily AFULGI_00016670 1d3a5ebd6cc57d76c0d8a426cce1aefc 412 SMART SM00460 172 226 8.2E-16 T 01-11-2018 IPR002931 Transglutaminase-like AFULGI_00016250 7b72e5b241bae8301ee64df3fdd829b0 81 TIGRFAM TIGR03831 YgiT_finger: YgiT-type zinc finger domain 6 50 2.0E-14 T 01-11-2018 IPR022453 Zinc finger, MqsA-type AFULGI_00017210 4a8b91df7bfcdef7c74bebee5b7fcef1 226 SUPERFAMILY SSF52540 3 224 1.46E-79 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00017210 4a8b91df7bfcdef7c74bebee5b7fcef1 226 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFULGI_00017210 4a8b91df7bfcdef7c74bebee5b7fcef1 226 Pfam PF00005 ABC transporter 23 171 1.2E-37 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFULGI_00017210 4a8b91df7bfcdef7c74bebee5b7fcef1 226 SMART SM00382 32 220 1.2E-19 T 01-11-2018 IPR003593 AAA+ ATPase domain AFULGI_00017210 4a8b91df7bfcdef7c74bebee5b7fcef1 226 Gene3D G3DSA:3.40.50.300 1 225 4.2E-78 T 01-11-2018 AFULGI_00013220 b669485060dbffb0c8478086f17fcde7 275 SUPERFAMILY SSF103481 35 128 8.11E-11 T 01-11-2018 AFULGI_00013220 b669485060dbffb0c8478086f17fcde7 275 Pfam PF00892 EamA-like transporter family 134 267 3.3E-9 T 01-11-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFULGI_00013220 b669485060dbffb0c8478086f17fcde7 275 Pfam PF00892 EamA-like transporter family 4 125 2.6E-8 T 01-11-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFULGI_00013220 b669485060dbffb0c8478086f17fcde7 275 SUPERFAMILY SSF103481 172 270 2.48E-7 T 01-11-2018 AFULGI_00018630 a490b1cec81dac9b987ff14060cb4d3e 736 SUPERFAMILY SSF52402 470 598 2.34E-20 T 01-11-2018 AFULGI_00018630 a490b1cec81dac9b987ff14060cb4d3e 736 Gene3D G3DSA:3.40.50.620 605 729 1.5E-9 T 01-11-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFULGI_00018630 a490b1cec81dac9b987ff14060cb4d3e 736 PRINTS PR01438 Universal stress protein signature 558 570 1.1E-5 T 01-11-2018 IPR006015 Universal stress protein A AFULGI_00018630 a490b1cec81dac9b987ff14060cb4d3e 736 PRINTS PR01438 Universal stress protein signature 576 598 1.1E-5 T 01-11-2018 IPR006015 Universal stress protein A AFULGI_00018630 a490b1cec81dac9b987ff14060cb4d3e 736 TIGRFAM TIGR00909 2A0306: amino acid transporter 7 443 3.9E-171 T 01-11-2018 IPR004758 Amino acid transporter AFULGI_00018630 a490b1cec81dac9b987ff14060cb4d3e 736 Gene3D G3DSA:3.40.50.620 468 600 6.3E-16 T 01-11-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFULGI_00018630 a490b1cec81dac9b987ff14060cb4d3e 736 Gene3D G3DSA:1.20.1740.10 6 467 9.8E-110 T 01-11-2018 AFULGI_00018630 a490b1cec81dac9b987ff14060cb4d3e 736 SUPERFAMILY SSF52402 607 728 4.35E-11 T 01-11-2018 AFULGI_00018630 a490b1cec81dac9b987ff14060cb4d3e 736 Pfam PF13520 Amino acid permease 11 423 2.1E-48 T 01-11-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 AFULGI_00018630 a490b1cec81dac9b987ff14060cb4d3e 736 Pfam PF00582 Universal stress protein family 471 598 8.7E-21 T 01-11-2018 IPR006016 UspA AFULGI_00019360 63c54ff1f729e8175a88793615b65f92 215 Pfam PF02593 Domain of unknown function 8 212 3.6E-66 T 01-11-2018 IPR003745 Protein of unknown function DUF166 AFULGI_00020270 a493411bc513bf27c9ab55a5a245f482 60 Hamap MF_00751 Preprotein translocase subunit SecG [secG]. 1 56 17.603 T 01-11-2018 IPR023531 Preprotein translocase subunit SecG AFULGI_00020270 a493411bc513bf27c9ab55a5a245f482 60 ProDom PD048325 SUBUNIT PREPROTEIN TRANSLOCASE SECG HOMOLOG TRANSLOCATION MEMBRANE SEC61 TRANSMEMBRANE BETA 14 54 7.0E-16 T 01-11-2018 AFULGI_00020270 a493411bc513bf27c9ab55a5a245f482 60 Pfam PF03911 Sec61beta family 16 56 2.9E-17 T 01-11-2018 IPR016482 Protein transport protein SecG/Sec61-beta/Sbh Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 AFULGI_00014660 3aa47df3c5e596394c330419bf62ef4a 320 Pfam PF01895 PhoU domain 139 223 8.9E-12 T 01-11-2018 IPR026022 PhoU domain AFULGI_00014660 3aa47df3c5e596394c330419bf62ef4a 320 Pfam PF01895 PhoU domain 235 313 4.3E-6 T 01-11-2018 IPR026022 PhoU domain AFULGI_00014660 3aa47df3c5e596394c330419bf62ef4a 320 Gene3D G3DSA:2.10.260.10 17 53 5.7E-7 T 01-11-2018 AFULGI_00014660 3aa47df3c5e596394c330419bf62ef4a 320 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 20 54 8.1E-8 T 01-11-2018 IPR007159 SpoVT-AbrB domain GO:0003677 AFULGI_00014660 3aa47df3c5e596394c330419bf62ef4a 320 Gene3D G3DSA:1.20.58.220 230 319 1.5E-5 T 01-11-2018 IPR038078 PhoU-like domain superfamily AFULGI_00014660 3aa47df3c5e596394c330419bf62ef4a 320 Gene3D G3DSA:1.20.58.220 136 229 1.4E-12 T 01-11-2018 IPR038078 PhoU-like domain superfamily AFULGI_00014660 3aa47df3c5e596394c330419bf62ef4a 320 SUPERFAMILY SSF109755 128 316 2.79E-25 T 01-11-2018 AFULGI_00014660 3aa47df3c5e596394c330419bf62ef4a 320 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 16 57 1.1E-11 T 01-11-2018 IPR007159 SpoVT-AbrB domain GO:0003677 AFULGI_00014660 3aa47df3c5e596394c330419bf62ef4a 320 SMART SM00966 14 59 1.0E-12 T 01-11-2018 IPR007159 SpoVT-AbrB domain GO:0003677 AFULGI_00014660 3aa47df3c5e596394c330419bf62ef4a 320 SUPERFAMILY SSF89447 18 57 5.93E-8 T 01-11-2018 IPR037914 SpoVT-AbrB domain superfamily AFULGI_00025980 518d648cdf9f8307abe81770168196a0 344 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 217 239 - T 01-11-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 AFULGI_00025980 518d648cdf9f8307abe81770168196a0 344 Pfam PF01066 CDP-alcohol phosphatidyltransferase 172 239 2.3E-10 T 01-11-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 AFULGI_00025980 518d648cdf9f8307abe81770168196a0 344 Gene3D G3DSA:1.20.120.1760 142 344 4.5E-84 T 01-11-2018 AFULGI_00025980 518d648cdf9f8307abe81770168196a0 344 Gene3D G3DSA:3.90.550.30 1 135 1.9E-80 T 01-11-2018 AFULGI_00003340 f91fa4a5a3b46f304517c5cffe83c5a2 245 SUPERFAMILY SSF55979 123 243 4.52E-28 T 01-11-2018 AFULGI_00003340 f91fa4a5a3b46f304517c5cffe83c5a2 245 Pfam PF02747 Proliferating cell nuclear antigen, C-terminal domain 122 231 4.1E-9 T 01-11-2018 IPR022649 Proliferating cell nuclear antigen, PCNA, C-terminal GO:0003677|GO:0006275 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 AFULGI_00003340 f91fa4a5a3b46f304517c5cffe83c5a2 245 Pfam PF00705 Proliferating cell nuclear antigen, N-terminal domain 6 95 1.7E-11 T 01-11-2018 IPR022648 Proliferating cell nuclear antigen, PCNA, N-terminal GO:0003677|GO:0006275 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 AFULGI_00003340 f91fa4a5a3b46f304517c5cffe83c5a2 245 Hamap MF_00317 DNA polymerase sliding clamp [pcn]. 1 242 26.921 T 01-11-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 AFULGI_00003340 f91fa4a5a3b46f304517c5cffe83c5a2 245 Gene3D G3DSA:3.70.10.10 1 245 5.7E-89 T 01-11-2018 AFULGI_00003340 f91fa4a5a3b46f304517c5cffe83c5a2 245 SUPERFAMILY SSF55979 1 122 1.16E-27 T 01-11-2018 AFULGI_00003340 f91fa4a5a3b46f304517c5cffe83c5a2 245 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 9 28 2.1E-12 T 01-11-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 AFULGI_00003340 f91fa4a5a3b46f304517c5cffe83c5a2 245 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 33 51 2.1E-12 T 01-11-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 AFULGI_00003340 f91fa4a5a3b46f304517c5cffe83c5a2 245 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 55 79 2.1E-12 T 01-11-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 AFULGI_00003340 f91fa4a5a3b46f304517c5cffe83c5a2 245 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 228 245 2.1E-12 T 01-11-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 AFULGI_00003340 f91fa4a5a3b46f304517c5cffe83c5a2 245 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 189 203 2.1E-12 T 01-11-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 AFULGI_00003340 f91fa4a5a3b46f304517c5cffe83c5a2 245 ProSitePatterns PS01251 Proliferating cell nuclear antigen signature 1. 33 56 - T 01-11-2018 IPR022659 Proliferating cell nuclear antigen, PCNA, conserved site Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 AFULGI_00014410 d94accfe4101c8c105df64eda8f6f1a8 336 PIRSF PIRSF004869 3 310 3.9E-99 T 01-11-2018 IPR016431 Pyruvate-formate lyase-activating enzyme, predicted AFULGI_00014410 d94accfe4101c8c105df64eda8f6f1a8 336 SMART SM00729 72 276 0.0044 T 01-11-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 AFULGI_00014410 d94accfe4101c8c105df64eda8f6f1a8 336 TIGRFAM TIGR04337 AmmeMemoSam_rS: AmmeMemoRadiSam system radical SAM enzyme 8 331 3.4E-108 T 01-11-2018 IPR027596 AmmeMemoRadiSam system radical SAM enzyme AFULGI_00014410 d94accfe4101c8c105df64eda8f6f1a8 336 Pfam PF04055 Radical SAM superfamily 81 232 1.4E-21 T 01-11-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFULGI_00014410 d94accfe4101c8c105df64eda8f6f1a8 336 Gene3D G3DSA:3.20.20.70 67 283 1.5E-36 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFULGI_00014410 d94accfe4101c8c105df64eda8f6f1a8 336 SUPERFAMILY SSF102114 50 311 2.62E-38 T 01-11-2018 AFULGI_00002040 fccc6e15811660fb3ba13abcf8cfa8c3 389 Pfam PF02080 TrkA-C domain 123 175 4.2E-9 T 01-11-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 AFULGI_00002040 fccc6e15811660fb3ba13abcf8cfa8c3 389 Gene3D G3DSA:3.40.50.720 2 118 5.2E-12 T 01-11-2018 AFULGI_00002040 fccc6e15811660fb3ba13abcf8cfa8c3 389 Gene3D G3DSA:3.30.70.1450 119 184 9.0E-8 T 01-11-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 AFULGI_00002040 fccc6e15811660fb3ba13abcf8cfa8c3 389 Pfam PF02254 TrkA-N domain 3 105 5.0E-13 T 01-11-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 AFULGI_00002040 fccc6e15811660fb3ba13abcf8cfa8c3 389 SUPERFAMILY SSF51735 10 101 9.74E-10 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily AFULGI_00002040 fccc6e15811660fb3ba13abcf8cfa8c3 389 SUPERFAMILY SSF116726 121 178 3.01E-9 T 01-11-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 AFULGI_00000910 b2f8d86b2b6613b6eca5b8a4368e6d04 261 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 69 247 2.1E-15 T 01-11-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFULGI_00000910 b2f8d86b2b6613b6eca5b8a4368e6d04 261 Gene3D G3DSA:1.10.3720.10 1 261 3.3E-96 T 01-11-2018 IPR035906 MetI-like superfamily AFULGI_00000910 b2f8d86b2b6613b6eca5b8a4368e6d04 261 SUPERFAMILY SSF161098 2 249 1.12E-52 T 01-11-2018 IPR035906 MetI-like superfamily AFULGI_00021090 7ac7d3f2f97ab12f80fae514bd4d56b9 557 SUPERFAMILY SSF56801 21 551 8.24E-115 T 01-11-2018 AFULGI_00021090 7ac7d3f2f97ab12f80fae514bd4d56b9 557 Pfam PF00501 AMP-binding enzyme 28 455 8.0E-76 T 01-11-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFULGI_00021090 7ac7d3f2f97ab12f80fae514bd4d56b9 557 Gene3D G3DSA:3.40.50.12780 2 450 2.8E-79 T 01-11-2018 AFULGI_00021090 7ac7d3f2f97ab12f80fae514bd4d56b9 557 Gene3D G3DSA:3.30.300.310 451 556 4.9E-32 T 01-11-2018 AFULGI_00021090 7ac7d3f2f97ab12f80fae514bd4d56b9 557 Pfam PF13193 AMP-binding enzyme C-terminal domain 464 540 7.1E-15 T 01-11-2018 IPR025110 AMP-binding enzyme, C-terminal domain AFULGI_00024490 1a0c7c5c659ee4069b35085e6fdcf341 362 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 284 290 - T 01-11-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 AFULGI_00024490 1a0c7c5c659ee4069b35085e6fdcf341 362 ProSitePatterns PS01261 Uncharacterized protein family UPF0020 signature. 195 206 - T 01-11-2018 IPR000241 Putative RNA methylase domain AFULGI_00024490 1a0c7c5c659ee4069b35085e6fdcf341 362 SUPERFAMILY SSF53335 147 323 5.72E-32 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFULGI_00024490 1a0c7c5c659ee4069b35085e6fdcf341 362 Gene3D G3DSA:3.40.50.150 161 362 1.3E-43 T 01-11-2018 AFULGI_00024490 1a0c7c5c659ee4069b35085e6fdcf341 362 Pfam PF01170 Putative RNA methylase family UPF0020 162 355 6.3E-69 T 01-11-2018 IPR000241 Putative RNA methylase domain AFULGI_00024490 1a0c7c5c659ee4069b35085e6fdcf341 362 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 281 293 9.6E-7 T 01-11-2018 AFULGI_00024490 1a0c7c5c659ee4069b35085e6fdcf341 362 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 193 207 9.6E-7 T 01-11-2018 AFULGI_00024490 1a0c7c5c659ee4069b35085e6fdcf341 362 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 302 326 9.6E-7 T 01-11-2018 AFULGI_00024490 1a0c7c5c659ee4069b35085e6fdcf341 362 SUPERFAMILY SSF143437 32 153 2.09E-16 T 01-11-2018 AFULGI_00024490 1a0c7c5c659ee4069b35085e6fdcf341 362 Gene3D G3DSA:3.30.2130.30 1 160 2.6E-39 T 01-11-2018 AFULGI_00024490 1a0c7c5c659ee4069b35085e6fdcf341 362 SMART SM00981 57 153 4.4E-21 T 01-11-2018 IPR004114 THUMP domain GO:0003723 AFULGI_00024490 1a0c7c5c659ee4069b35085e6fdcf341 362 Pfam PF02926 THUMP domain 18 153 6.3E-28 T 01-11-2018 IPR004114 THUMP domain GO:0003723 AFULGI_00003350 d9d068ccb189a6c542a8ae5c513e84aa 370 SUPERFAMILY SSF140914 10 274 1.29E-34 T 01-11-2018 AFULGI_00003350 d9d068ccb189a6c542a8ae5c513e84aa 370 Hamap MF_00701 DNA primase large subunit PriL [priL]. 11 369 35.645 T 01-11-2018 IPR023642 DNA primase large subunit PriL GO:0003896 AFULGI_00003350 d9d068ccb189a6c542a8ae5c513e84aa 370 Pfam PF04104 Eukaryotic and archaeal DNA primase, large subunit 175 350 2.1E-34 T 01-11-2018 IPR007238 DNA primase large subunit, eukaryotic/archaeal GO:0003896|GO:0006269 Reactome: R-HSA-113501|Reactome: R-HSA-174411|Reactome: R-HSA-174430|Reactome: R-HSA-68952|Reactome: R-HSA-68962|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183 AFULGI_00022720 5a640be42db148bf6ba07a96f97dd18f 83 SUPERFAMILY SSF46785 5 76 3.56E-19 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00022720 5a640be42db148bf6ba07a96f97dd18f 83 Gene3D G3DSA:1.10.10.10 1 82 5.1E-32 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00022720 5a640be42db148bf6ba07a96f97dd18f 83 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 12 67 2.0E-10 T 01-11-2018 IPR002831 Transcription regulator TrmB, N-terminal AFULGI_00008080 b7524825f1f163eed15567b66dd05839 217 TIGRFAM TIGR00123 cbiM: cobalamin biosynthesis protein CbiM 1 213 5.0E-110 T 01-11-2018 IPR018024 Cobalamin (vitamin B12) transport protein CbiM GO:0006824|GO:0009236|GO:0016021|GO:0043190 AFULGI_00008080 b7524825f1f163eed15567b66dd05839 217 Pfam PF01891 Cobalt uptake substrate-specific transmembrane region 2 210 1.2E-51 T 01-11-2018 IPR002751 Metal transport protein CbiM/NikMN GO:0000041|GO:0016021 AFULGI_00008080 b7524825f1f163eed15567b66dd05839 217 Hamap MF_01462 Cobalt transport protein CbiM [cbiM]. 1 216 28.372 T 01-11-2018 IPR018024 Cobalamin (vitamin B12) transport protein CbiM GO:0006824|GO:0009236|GO:0016021|GO:0043190 AFULGI_00008080 b7524825f1f163eed15567b66dd05839 217 Gene3D G3DSA:1.10.1760.20 1 210 1.2E-53 T 01-11-2018 AFULGI_00006400 96b95dec29839b2e073e500e7fcbda30 142 PIRSF PIRSF006031 2 142 1.9E-64 T 01-11-2018 IPR007176 Protein of unknown function DUF365 AFULGI_00006400 96b95dec29839b2e073e500e7fcbda30 142 Gene3D G3DSA:2.30.130.30 1 142 4.2E-63 T 01-11-2018 AFULGI_00006400 96b95dec29839b2e073e500e7fcbda30 142 ProDom PD020174 PH0907 MJECS03 PLASMID PF0569 AF2351 41 142 1.0E-40 T 01-11-2018 IPR007176 Protein of unknown function DUF365 AFULGI_00006400 96b95dec29839b2e073e500e7fcbda30 142 Pfam PF04033 Domain of unknown function (DUF365) 41 141 9.1E-46 T 01-11-2018 IPR007176 Protein of unknown function DUF365 AFULGI_00017550 7783804539ac5010e8c1dd36b8101653 337 Pfam PF00672 HAMP domain 278 325 5.3E-11 T 01-11-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFULGI_00017550 7783804539ac5010e8c1dd36b8101653 337 Gene3D G3DSA:1.20.1480.50 236 337 1.1E-40 T 01-11-2018 AFULGI_00017550 7783804539ac5010e8c1dd36b8101653 337 SUPERFAMILY SSF158472 278 326 1.57E-12 T 01-11-2018 AFULGI_00017550 7783804539ac5010e8c1dd36b8101653 337 SMART SM00304 277 330 1.7E-11 T 01-11-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFULGI_00002520 6150e2c4f600462bc2aef8c10f37dd7f 391 TIGRFAM TIGR00529 AF0261: integral membrane protein, TIGR00529 family 3 391 2.7E-163 T 01-11-2018 IPR005253 Conserved hypothetical protein CHP00529 AFULGI_00002520 6150e2c4f600462bc2aef8c10f37dd7f 391 Pfam PF04165 Protein of unknown function (DUF401) 3 391 1.8E-187 T 01-11-2018 IPR007294 Protein of unknown function DUF401 AFULGI_00005200 505e152f37460efb98775928f29600f0 289 SUPERFAMILY SSF103481 184 286 1.44E-18 T 01-11-2018 AFULGI_00005200 505e152f37460efb98775928f29600f0 289 Pfam PF00892 EamA-like transporter family 6 135 4.1E-26 T 01-11-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFULGI_00005200 505e152f37460efb98775928f29600f0 289 Pfam PF00892 EamA-like transporter family 149 284 1.2E-29 T 01-11-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFULGI_00005200 505e152f37460efb98775928f29600f0 289 SUPERFAMILY SSF103481 38 138 3.14E-14 T 01-11-2018 AFULGI_00005690 2d8fd2e3a87b2da2df8c0144aa61b923 265 PIRSF PIRSF006661 2 264 1.6E-101 T 01-11-2018 IPR005232 Pyridinium-3,5-bisthiocarboxylic acid mononucleotide synthase LarE GO:0016783 AFULGI_00005690 2d8fd2e3a87b2da2df8c0144aa61b923 265 SUPERFAMILY SSF52402 20 218 1.52E-34 T 01-11-2018 AFULGI_00005690 2d8fd2e3a87b2da2df8c0144aa61b923 265 Pfam PF02540 NAD synthase 17 90 2.4E-9 T 01-11-2018 IPR022310 NAD/GMP synthase AFULGI_00005690 2d8fd2e3a87b2da2df8c0144aa61b923 265 Gene3D G3DSA:3.40.50.620 4 169 1.3E-25 T 01-11-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFULGI_00005690 2d8fd2e3a87b2da2df8c0144aa61b923 265 TIGRFAM TIGR00268 TIGR00268: TIGR00268 family protein 8 262 8.0E-127 T 01-11-2018 IPR005232 Pyridinium-3,5-bisthiocarboxylic acid mononucleotide synthase LarE GO:0016783 AFULGI_00021900 fc2dd2f5a0757afb5a0279cb96bcfbb0 234 SUPERFAMILY SSF69336 31 213 7.98E-40 T 01-11-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 AFULGI_00021900 fc2dd2f5a0757afb5a0279cb96bcfbb0 234 Pfam PF01493 GXGXG motif 79 199 1.7E-12 T 01-11-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0016491|GO:0055114 AFULGI_00021900 fc2dd2f5a0757afb5a0279cb96bcfbb0 234 TIGRFAM TIGR03122 one_C_dehyd_C: formylmethanofuran dehydrogenase subunit C 2 217 5.1E-83 T 01-11-2018 IPR017550 Formylmethanofuran dehydrogenase subunit C GO:0015948|GO:0018493|GO:0046914|GO:0055114 KEGG: 00680+1.2.7.12|MetaCyc: PWY-5209|MetaCyc: PWY-7784 AFULGI_00021900 fc2dd2f5a0757afb5a0279cb96bcfbb0 234 Gene3D G3DSA:2.160.20.60 60 226 2.3E-11 T 01-11-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 AFULGI_00021740 d579c46c8e902499a0d9b22824cb4c16 132 SUPERFAMILY SSF50193 2 132 3.66E-46 T 01-11-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 AFULGI_00021740 d579c46c8e902499a0d9b22824cb4c16 132 Pfam PF00238 Ribosomal protein L14p/L23e 14 131 4.0E-37 T 01-11-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 AFULGI_00021740 d579c46c8e902499a0d9b22824cb4c16 132 ProSitePatterns PS00049 Ribosomal protein L14 signature. 71 97 - T 01-11-2018 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00021740 d579c46c8e902499a0d9b22824cb4c16 132 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 11 132 20.628 T 01-11-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 AFULGI_00021740 d579c46c8e902499a0d9b22824cb4c16 132 Gene3D G3DSA:2.40.150.20 1 132 3.6E-52 T 01-11-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 AFULGI_00021740 d579c46c8e902499a0d9b22824cb4c16 132 TIGRFAM TIGR03673 uL14_arch: 50S ribosomal protein uL14 2 132 3.5E-65 T 01-11-2018 IPR019971 Ribosomal protein L14P, archaeal AFULGI_00021740 d579c46c8e902499a0d9b22824cb4c16 132 SMART SM01374 11 132 3.4E-61 T 01-11-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 AFULGI_00018650 2d0860587885ecea5d59980b5e2faf50 128 SMART SM00748 10 121 1.2E-40 T 01-11-2018 IPR007842 HEPN domain AFULGI_00018650 2d0860587885ecea5d59980b5e2faf50 128 SUPERFAMILY SSF81593 9 127 2.39E-22 T 01-11-2018 AFULGI_00018650 2d0860587885ecea5d59980b5e2faf50 128 Pfam PF05168 HEPN domain 6 126 2.2E-29 T 01-11-2018 IPR007842 HEPN domain AFULGI_00018650 2d0860587885ecea5d59980b5e2faf50 128 Gene3D G3DSA:1.20.120.330 2 128 1.3E-23 T 01-11-2018 AFULGI_00006750 ed990b14282362caf90b97f4c57d6650 310 Gene3D G3DSA:3.40.50.300 3 297 8.1E-10 T 01-11-2018 AFULGI_00006750 ed990b14282362caf90b97f4c57d6650 310 SUPERFAMILY SSF52540 4 272 8.35E-15 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00005130 223cd061a636fd2baaae56470683aa0d 142 SUPERFAMILY SSF48695 44 123 2.42E-6 T 01-11-2018 IPR036280 Multiheme cytochrome superfamily AFULGI_00020420 e0ed9e6acd43305c0bd52438ae6d0602 189 Pfam PF00717 Peptidase S24-like 41 104 1.4E-5 T 01-11-2018 IPR015927 Peptidase S24/S26A/S26B/S26C AFULGI_00020420 e0ed9e6acd43305c0bd52438ae6d0602 189 SUPERFAMILY SSF51306 34 186 1.73E-17 T 01-11-2018 IPR036286 LexA/Signal peptidase-like superfamily AFULGI_00014730 c863c02775a0cdf0c1bbd09c7fa1c1e0 340 Gene3D G3DSA:2.160.10.10 2 119 7.7E-10 T 01-11-2018 AFULGI_00014730 c863c02775a0cdf0c1bbd09c7fa1c1e0 340 SUPERFAMILY SSF51161 16 105 3.01E-11 T 01-11-2018 IPR011004 Trimeric LpxA-like superfamily AFULGI_00004710 308b5aba6af3e779972b4fdebf852353 387 SUPERFAMILY SSF51905 1 343 2.29E-41 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFULGI_00004710 308b5aba6af3e779972b4fdebf852353 387 Pfam PF01494 FAD binding domain 2 304 9.5E-15 T 01-11-2018 IPR002938 FAD-binding domain GO:0071949 AFULGI_00004710 308b5aba6af3e779972b4fdebf852353 387 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 7.8E-14 T 01-11-2018 AFULGI_00004710 308b5aba6af3e779972b4fdebf852353 387 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 144 159 7.8E-14 T 01-11-2018 AFULGI_00004710 308b5aba6af3e779972b4fdebf852353 387 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 266 281 7.8E-14 T 01-11-2018 AFULGI_00004710 308b5aba6af3e779972b4fdebf852353 387 Gene3D G3DSA:3.30.9.10 67 359 1.4E-123 T 01-11-2018 AFULGI_00004710 308b5aba6af3e779972b4fdebf852353 387 Gene3D G3DSA:3.50.50.60 2 340 1.4E-123 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFULGI_00004710 308b5aba6af3e779972b4fdebf852353 387 TIGRFAM TIGR02032 GG-red-SF: geranylgeranyl reductase family 2 300 1.5E-73 T 01-11-2018 IPR011777 Geranylgeranyl reductase family GO:0016628|GO:0055114 AFULGI_00004710 308b5aba6af3e779972b4fdebf852353 387 Hamap MF_01287 Digeranylgeranylglycerophospholipid reductase. 1 387 45.815 T 01-11-2018 IPR023590 Digeranylgeranylglycerophospholipid reductase GO:0016628|GO:0045550|GO:0046467|GO:0055114 KEGG: 00564+1.3.7.11|MetaCyc: PWY-6349 AFULGI_00025630 fc7835af54b6ea61cef7837b3f429b9d 262 SUPERFAMILY SSF56281 22 221 4.87E-35 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFULGI_00025630 fc7835af54b6ea61cef7837b3f429b9d 262 Pfam PF00753 Metallo-beta-lactamase superfamily 34 185 2.5E-11 T 01-11-2018 IPR001279 Metallo-beta-lactamase AFULGI_00025630 fc7835af54b6ea61cef7837b3f429b9d 262 SMART SM00849 15 185 7.9E-26 T 01-11-2018 IPR001279 Metallo-beta-lactamase AFULGI_00025630 fc7835af54b6ea61cef7837b3f429b9d 262 Gene3D G3DSA:3.60.15.10 14 221 3.0E-35 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFULGI_00023650 b6a807ce116c8021122a3c695164398b 395 Hamap MF_01074 Pyridinium-3,5-bisthiocarboxylic acid mononucleotide nickel insertion protein [larC]. 1 387 34.414 T 01-11-2018 IPR002822 Nickel insertion protein AFULGI_00023650 b6a807ce116c8021122a3c695164398b 395 Pfam PF01969 Protein of unknown function DUF111 5 377 1.4E-108 T 01-11-2018 IPR002822 Nickel insertion protein AFULGI_00023650 b6a807ce116c8021122a3c695164398b 395 Gene3D G3DSA:3.30.70.1380 231 324 1.2E-27 T 01-11-2018 AFULGI_00023650 b6a807ce116c8021122a3c695164398b 395 TIGRFAM TIGR00299 TIGR00299: TIGR00299 family protein 3 377 3.0E-171 T 01-11-2018 IPR002822 Nickel insertion protein AFULGI_00003660 8df0e96d55f276cc9b5f55fe3c972c74 175 Pfam PF01402 Ribbon-helix-helix protein, copG family 4 39 8.6E-11 T 01-11-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 AFULGI_00008370 23a23d84063440ffbd82b54673007db8 322 Pfam PF02833 DHHA2 domain 195 318 2.6E-23 T 01-11-2018 IPR004097 DHHA2 domain GO:0005737|GO:0016462 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 AFULGI_00008370 23a23d84063440ffbd82b54673007db8 322 Gene3D G3DSA:3.10.310.20 202 322 1.2E-41 T 01-11-2018 IPR038222 DHHA2 domain superfamily KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 AFULGI_00008370 23a23d84063440ffbd82b54673007db8 322 Hamap MF_00207 Probable manganese-dependent inorganic pyrophosphatase [ppaC]. 4 321 45.326 T 01-11-2018 IPR022934 Manganese-dependent inorganic pyrophosphatase, probable GO:0004427 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 AFULGI_00008370 23a23d84063440ffbd82b54673007db8 322 SUPERFAMILY SSF64182 5 319 2.88E-75 T 01-11-2018 IPR038763 DHH phosphoesterase superfamily AFULGI_00008370 23a23d84063440ffbd82b54673007db8 322 Pfam PF01368 DHH family 5 157 1.9E-27 T 01-11-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 AFULGI_00008370 23a23d84063440ffbd82b54673007db8 322 SMART SM01131 193 319 8.7E-57 T 01-11-2018 IPR004097 DHHA2 domain GO:0005737|GO:0016462 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 AFULGI_00008370 23a23d84063440ffbd82b54673007db8 322 Gene3D G3DSA:3.90.1640.10 3 200 2.4E-72 T 01-11-2018 AFULGI_00012980 f76b74146862eb2c2ce59824be0293d6 338 SMART SM00882 39 260 1.2E-39 T 01-11-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 AFULGI_00012980 f76b74146862eb2c2ce59824be0293d6 338 Gene3D G3DSA:3.40.1080.10 40 321 2.5E-90 T 01-11-2018 AFULGI_00012980 f76b74146862eb2c2ce59824be0293d6 338 Pfam PF01144 Coenzyme A transferase 39 260 7.0E-54 T 01-11-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 AFULGI_00012980 f76b74146862eb2c2ce59824be0293d6 338 SUPERFAMILY SSF100950 37 318 4.49E-78 T 01-11-2018 IPR037171 NagB/RpiA transferase-like AFULGI_00012980 f76b74146862eb2c2ce59824be0293d6 338 Gene3D G3DSA:3.30.30.40 153 188 2.5E-90 T 01-11-2018 AFULGI_00022340 ae9ffb07f5b49f80891ed3b2eb3f93d1 314 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 233 249 9.9E-61 T 01-11-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 AFULGI_00022340 ae9ffb07f5b49f80891ed3b2eb3f93d1 314 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 143 162 9.9E-61 T 01-11-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 AFULGI_00022340 ae9ffb07f5b49f80891ed3b2eb3f93d1 314 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 258 273 9.9E-61 T 01-11-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 AFULGI_00022340 ae9ffb07f5b49f80891ed3b2eb3f93d1 314 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 287 306 9.9E-61 T 01-11-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 AFULGI_00022340 ae9ffb07f5b49f80891ed3b2eb3f93d1 314 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 181 200 9.9E-61 T 01-11-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 AFULGI_00022340 ae9ffb07f5b49f80891ed3b2eb3f93d1 314 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 113 127 9.9E-61 T 01-11-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 AFULGI_00022340 ae9ffb07f5b49f80891ed3b2eb3f93d1 314 PIRSF PIRSF001415 1 314 2.4E-145 T 01-11-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 AFULGI_00022340 ae9ffb07f5b49f80891ed3b2eb3f93d1 314 SUPERFAMILY SSF51569 3 313 3.22E-133 T 01-11-2018 AFULGI_00022340 ae9ffb07f5b49f80891ed3b2eb3f93d1 314 Gene3D G3DSA:3.20.20.70 1 314 1.1E-143 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFULGI_00022340 ae9ffb07f5b49f80891ed3b2eb3f93d1 314 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 233 245 - T 01-11-2018 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 AFULGI_00022340 ae9ffb07f5b49f80891ed3b2eb3f93d1 314 SMART SM01004 1 313 2.4E-221 T 01-11-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 AFULGI_00022340 ae9ffb07f5b49f80891ed3b2eb3f93d1 314 Pfam PF00490 Delta-aminolevulinic acid dehydratase 2 311 5.3E-144 T 01-11-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 AFULGI_00009600 6f5c1d46f6803d1517b3ecff8d967080 77 Pfam PF01423 LSM domain 8 72 3.1E-22 T 01-11-2018 IPR001163 LSM domain, eukaryotic/archaea-type AFULGI_00009600 6f5c1d46f6803d1517b3ecff8d967080 77 Gene3D G3DSA:2.30.30.100 2 77 3.3E-26 T 01-11-2018 AFULGI_00009600 6f5c1d46f6803d1517b3ecff8d967080 77 SMART SM00651 7 72 1.8E-25 T 01-11-2018 IPR001163 LSM domain, eukaryotic/archaea-type AFULGI_00009600 6f5c1d46f6803d1517b3ecff8d967080 77 Hamap MF_00257 Putative snRNP Sm-like protein. 1 72 25.424 T 01-11-2018 IPR022901 snRNP Sm-like, putative, archaea AFULGI_00009600 6f5c1d46f6803d1517b3ecff8d967080 77 SUPERFAMILY SSF50182 3 74 2.77E-20 T 01-11-2018 IPR010920 LSM domain superfamily AFULGI_00011880 eb21b0599ef88d353b18dc8a449a6fb0 61 Pfam PF01954 Protein of unknown function DUF104 1 54 4.4E-21 T 01-11-2018 IPR008203 Uncharacterised protein family UPF0165 AFULGI_00011880 eb21b0599ef88d353b18dc8a449a6fb0 61 SUPERFAMILY SSF141694 1 57 7.59E-17 T 01-11-2018 AFULGI_00011880 eb21b0599ef88d353b18dc8a449a6fb0 61 Gene3D G3DSA:4.10.1150.10 1 61 1.0E-19 T 01-11-2018 IPR024069 AF2212-like domain superfamily AFULGI_00025240 90ecc4ea1bbe833a67528c52cda72019 336 TIGRFAM TIGR00374 TIGR00374: TIGR00374 family protein 12 333 2.8E-112 T 01-11-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD AFULGI_00025240 90ecc4ea1bbe833a67528c52cda72019 336 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 9 317 7.7E-46 T 01-11-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD AFULGI_00017220 1f2def04846bbf650844e833eca34dad 375 Pfam PF02687 FtsX-like permease family 276 368 7.5E-12 T 01-11-2018 IPR003838 ABC transporter permease protein domain GO:0016020 AFULGI_00017220 1f2def04846bbf650844e833eca34dad 375 Pfam PF12704 MacB-like periplasmic core domain 17 215 2.7E-26 T 01-11-2018 IPR025857 MacB-like periplasmic core domain AFULGI_00007920 b4b296ffb7fc0e20227f69277a671a8a 753 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 457 742 7.5E-86 T 01-11-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 AFULGI_00007920 b4b296ffb7fc0e20227f69277a671a8a 753 SUPERFAMILY SSF56059 3 362 8.0E-109 T 01-11-2018 AFULGI_00007920 b4b296ffb7fc0e20227f69277a671a8a 753 Pfam PF00391 PEP-utilising enzyme, mobile domain 362 434 2.3E-27 T 01-11-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 AFULGI_00007920 b4b296ffb7fc0e20227f69277a671a8a 753 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 648 666 - T 01-11-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 AFULGI_00007920 b4b296ffb7fc0e20227f69277a671a8a 753 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 393 404 - T 01-11-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 AFULGI_00007920 b4b296ffb7fc0e20227f69277a671a8a 753 Gene3D G3DSA:3.30.1490.20 2 186 2.9E-79 T 01-11-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 AFULGI_00007920 b4b296ffb7fc0e20227f69277a671a8a 753 SUPERFAMILY SSF52009 329 441 1.27E-36 T 01-11-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 AFULGI_00007920 b4b296ffb7fc0e20227f69277a671a8a 753 Gene3D G3DSA:3.50.30.10 335 441 3.5E-43 T 01-11-2018 AFULGI_00007920 b4b296ffb7fc0e20227f69277a671a8a 753 PIRSF PIRSF000854 1 747 9.8E-200 T 01-11-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|MetaCyc: PWY-6142 AFULGI_00007920 b4b296ffb7fc0e20227f69277a671a8a 753 TIGRFAM TIGR01418 PEP_synth: phosphoenolpyruvate synthase 3 743 0.0 T 01-11-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|MetaCyc: PWY-6142 AFULGI_00007920 b4b296ffb7fc0e20227f69277a671a8a 753 SUPERFAMILY SSF51621 450 747 2.07E-89 T 01-11-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 AFULGI_00007920 b4b296ffb7fc0e20227f69277a671a8a 753 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 15 329 3.3E-120 T 01-11-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 AFULGI_00007920 b4b296ffb7fc0e20227f69277a671a8a 753 Gene3D G3DSA:3.30.470.20 187 334 4.5E-46 T 01-11-2018 AFULGI_00007920 b4b296ffb7fc0e20227f69277a671a8a 753 Gene3D G3DSA:3.20.20.60 442 753 1.9E-97 T 01-11-2018 AFULGI_00007920 b4b296ffb7fc0e20227f69277a671a8a 753 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 648 663 9.8E-14 T 01-11-2018 AFULGI_00007920 b4b296ffb7fc0e20227f69277a671a8a 753 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 485 504 9.8E-14 T 01-11-2018 AFULGI_00007920 b4b296ffb7fc0e20227f69277a671a8a 753 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 665 680 9.8E-14 T 01-11-2018 AFULGI_00007920 b4b296ffb7fc0e20227f69277a671a8a 753 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 701 713 9.8E-14 T 01-11-2018 AFULGI_00025930 d3be96a9ccc3f40e02bb6816e747069d 385 SUPERFAMILY SSF103473 4 378 9.55E-31 T 01-11-2018 IPR036259 MFS transporter superfamily AFULGI_00025930 d3be96a9ccc3f40e02bb6816e747069d 385 TIGRFAM TIGR00903 2A0129: major facilitator 4 family protein 14 376 1.6E-204 T 01-11-2018 IPR005277 Uncharacterised protein family, Major Facilitator Superfamily MSF4 AFULGI_00025930 d3be96a9ccc3f40e02bb6816e747069d 385 Gene3D G3DSA:1.20.1250.20 2 373 2.0E-21 T 01-11-2018 AFULGI_00025930 d3be96a9ccc3f40e02bb6816e747069d 385 Pfam PF07690 Major Facilitator Superfamily 10 340 2.4E-23 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFULGI_00013010 2e27590a6123d7e8cf505cbc8c1a7417 162 Gene3D G3DSA:3.30.70.20 38 161 8.2E-34 T 01-11-2018 AFULGI_00013010 2e27590a6123d7e8cf505cbc8c1a7417 162 Gene3D G3DSA:3.30.70.20 1 37 3.0E-5 T 01-11-2018 AFULGI_00013010 2e27590a6123d7e8cf505cbc8c1a7417 162 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 93 104 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFULGI_00013010 2e27590a6123d7e8cf505cbc8c1a7417 162 Pfam PF12837 4Fe-4S binding domain 7 24 2.5E-5 T 01-11-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFULGI_00013010 2e27590a6123d7e8cf505cbc8c1a7417 162 Pfam PF13247 4Fe-4S dicluster domain 55 146 7.4E-17 T 01-11-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFULGI_00013010 2e27590a6123d7e8cf505cbc8c1a7417 162 SUPERFAMILY SSF54862 4 158 1.57E-45 T 01-11-2018 AFULGI_00025270 5c0914e30007133631dbe0d4f10efc9b 67 Pfam PF10967 Protein of unknown function (DUF2769) 12 64 1.0E-14 T 01-11-2018 IPR020075 Uncharacterised protein family AF2234 AFULGI_00025270 5c0914e30007133631dbe0d4f10efc9b 67 ProDom PD054827 AF2234 MA2973 PREDICTED 12 67 9.0E-26 T 01-11-2018 IPR020075 Uncharacterised protein family AF2234 AFULGI_00005280 d8c830f49f6b4767c588599fc35132ea 149 PIRSF PIRSF022062 1 146 6.1E-66 T 01-11-2018 IPR016799 Uncharacterised conserved protein UCP022062 AFULGI_00005280 d8c830f49f6b4767c588599fc35132ea 149 Pfam PF08617 Kinase binding protein CGI-121 18 115 1.6E-10 T 01-11-2018 IPR013926 CGI121/TPRKB Reactome: R-HSA-6782315 AFULGI_00005280 d8c830f49f6b4767c588599fc35132ea 149 SUPERFAMILY SSF143870 20 120 1.27E-21 T 01-11-2018 IPR036504 CGI121/TPRKB superfamily Reactome: R-HSA-6782315 AFULGI_00005280 d8c830f49f6b4767c588599fc35132ea 149 Gene3D G3DSA:3.30.2380.10 3 126 3.2E-19 T 01-11-2018 IPR036504 CGI121/TPRKB superfamily Reactome: R-HSA-6782315 AFULGI_00005400 58c41452426fa5627d4b0c4821d3124c 253 Pfam PF00899 ThiF family 6 228 7.8E-60 T 01-11-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 AFULGI_00005400 58c41452426fa5627d4b0c4821d3124c 253 SUPERFAMILY SSF69572 4 234 2.88E-83 T 01-11-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 AFULGI_00005400 58c41452426fa5627d4b0c4821d3124c 253 Gene3D G3DSA:3.40.50.720 2 236 5.4E-77 T 01-11-2018 AFULGI_00010090 77fca90fc8c186e5baaf24ac772f374e 58 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 39 50 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFULGI_00010090 77fca90fc8c186e5baaf24ac772f374e 58 Gene3D G3DSA:3.30.70.20 28 58 1.5E-10 T 01-11-2018 AFULGI_00010090 77fca90fc8c186e5baaf24ac772f374e 58 Pfam PF00037 4Fe-4S binding domain 33 55 2.9E-10 T 01-11-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFULGI_00010090 77fca90fc8c186e5baaf24ac772f374e 58 Pfam PF00037 4Fe-4S binding domain 4 25 4.8E-6 T 01-11-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFULGI_00010090 77fca90fc8c186e5baaf24ac772f374e 58 Gene3D G3DSA:3.30.70.20 2 27 9.7E-6 T 01-11-2018 AFULGI_00010090 77fca90fc8c186e5baaf24ac772f374e 58 SUPERFAMILY SSF54862 3 57 1.61E-17 T 01-11-2018 AFULGI_00013240 bac7caa201eeeb7b8e6314615cadc494 212 Gene3D G3DSA:3.40.50.300 28 194 1.1E-6 T 01-11-2018 AFULGI_00013240 bac7caa201eeeb7b8e6314615cadc494 212 SUPERFAMILY SSF52540 95 200 7.43E-6 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00005070 da5e27cc94b4b4a08d5ad13a405c1836 576 Gene3D G3DSA:1.10.540.10 21 132 3.6E-39 T 01-11-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 AFULGI_00005070 da5e27cc94b4b4a08d5ad13a405c1836 576 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 249 396 5.6E-17 T 01-11-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AFULGI_00005070 da5e27cc94b4b4a08d5ad13a405c1836 576 SUPERFAMILY SSF47203 248 403 5.32E-27 T 01-11-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 AFULGI_00005070 da5e27cc94b4b4a08d5ad13a405c1836 576 Gene3D G3DSA:2.40.110.10 133 245 3.6E-39 T 01-11-2018 AFULGI_00005070 da5e27cc94b4b4a08d5ad13a405c1836 576 Gene3D G3DSA:1.20.140.10 246 394 3.6E-39 T 01-11-2018 AFULGI_00005070 da5e27cc94b4b4a08d5ad13a405c1836 576 SUPERFAMILY SSF56645 14 214 2.96E-21 T 01-11-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 AFULGI_00014430 4def361e2b374ac84d3dcfdbbcc2cc2e 182 Gene3D G3DSA:1.20.58.1030 1 115 7.1E-9 T 01-11-2018 AFULGI_00004770 059caa9d6c6c335b6b507f42a3f2cf60 344 SUPERFAMILY SSF52518 2 232 1.61E-69 T 01-11-2018 IPR029061 Thiamin diphosphate-binding fold AFULGI_00004770 059caa9d6c6c335b6b507f42a3f2cf60 344 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 13 193 7.6E-70 T 01-11-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 AFULGI_00004770 059caa9d6c6c335b6b507f42a3f2cf60 344 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 247 327 2.3E-16 T 01-11-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II AFULGI_00004770 059caa9d6c6c335b6b507f42a3f2cf60 344 Gene3D G3DSA:3.40.50.970 1 189 1.6E-75 T 01-11-2018 AFULGI_00004770 059caa9d6c6c335b6b507f42a3f2cf60 344 Gene3D G3DSA:3.40.50.920 238 342 7.5E-17 T 01-11-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 AFULGI_00004770 059caa9d6c6c335b6b507f42a3f2cf60 344 SUPERFAMILY SSF52922 245 340 7.98E-18 T 01-11-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 AFULGI_00006210 8e15aa1e3d4a5ecb2af471739cda7914 239 Gene3D G3DSA:1.10.10.10 154 231 8.8E-7 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00006210 8e15aa1e3d4a5ecb2af471739cda7914 239 SUPERFAMILY SSF46785 185 224 1.22E-6 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00006210 8e15aa1e3d4a5ecb2af471739cda7914 239 Pfam PF01022 Bacterial regulatory protein, arsR family 184 207 7.5E-5 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFULGI_00003110 560ed8aac9baf8a776ed95e15a8e5677 149 SUPERFAMILY SSF88723 2 143 1.49E-17 T 01-11-2018 IPR029060 PIN-like domain superfamily AFULGI_00003110 560ed8aac9baf8a776ed95e15a8e5677 149 Pfam PF01850 PIN domain 2 144 2.2E-32 T 01-11-2018 IPR002716 PIN domain AFULGI_00003110 560ed8aac9baf8a776ed95e15a8e5677 149 Gene3D G3DSA:3.40.50.1010 2 147 1.4E-14 T 01-11-2018 AFULGI_00003110 560ed8aac9baf8a776ed95e15a8e5677 149 SMART SM00670 1 140 1.6E-9 T 01-11-2018 IPR002716 PIN domain AFULGI_00002780 dad05457cda32142fbd77dcb4017c602 162 SUPERFAMILY SSF50249 25 155 2.23E-38 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold AFULGI_00002780 dad05457cda32142fbd77dcb4017c602 162 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 49 84 6.0E-14 T 01-11-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal AFULGI_00002780 dad05457cda32142fbd77dcb4017c602 162 Gene3D G3DSA:1.10.12.20 17 88 7.6E-18 T 01-11-2018 AFULGI_00002780 dad05457cda32142fbd77dcb4017c602 162 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 85 145 1.3E-14 T 01-11-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal AFULGI_00005780 35f0861fe4ec247d35af386ff851ce64 382 Hamap MF_00331 Cysteine desulfurase IscS [iscS]. 1 382 49.06 T 01-11-2018 IPR010240 Cysteine desulfurase IscS GO:0030170|GO:0031071|GO:0044571 KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250|Reactome: R-HSA-1362409|Reactome: R-HSA-947581 AFULGI_00005780 35f0861fe4ec247d35af386ff851ce64 382 Gene3D G3DSA:3.40.640.10 13 253 2.1E-155 T 01-11-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFULGI_00005780 35f0861fe4ec247d35af386ff851ce64 382 Pfam PF00266 Aminotransferase class-V 3 362 5.7E-80 T 01-11-2018 IPR000192 Aminotransferase class V domain AFULGI_00005780 35f0861fe4ec247d35af386ff851ce64 382 SUPERFAMILY SSF53383 2 372 1.18E-102 T 01-11-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFULGI_00005780 35f0861fe4ec247d35af386ff851ce64 382 Gene3D G3DSA:3.90.1150.10 3 363 2.1E-155 T 01-11-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFULGI_00005780 35f0861fe4ec247d35af386ff851ce64 382 PIRSF PIRSF005572 1 377 5.7E-131 T 01-11-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 AFULGI_00007600 6c37794013e282419bb2681260ef9126 242 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFULGI_00007600 6c37794013e282419bb2681260ef9126 242 SUPERFAMILY SSF52540 4 237 2.92E-84 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00007600 6c37794013e282419bb2681260ef9126 242 Pfam PF00005 ABC transporter 19 167 4.2E-39 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFULGI_00007600 6c37794013e282419bb2681260ef9126 242 PIRSF PIRSF039085 1 242 6.7E-121 T 01-11-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 AFULGI_00007600 6c37794013e282419bb2681260ef9126 242 SMART SM00382 28 215 7.9E-19 T 01-11-2018 IPR003593 AAA+ ATPase domain AFULGI_00007600 6c37794013e282419bb2681260ef9126 242 Gene3D G3DSA:3.40.50.300 4 242 1.5E-85 T 01-11-2018 AFULGI_00023380 13f87b980b2183b3ce3b455261fd4ad7 76 SMART SM01103 1 76 1.0E-14 T 01-11-2018 IPR001890 RNA-binding, CRM domain GO:0003723 AFULGI_00023380 13f87b980b2183b3ce3b455261fd4ad7 76 Gene3D G3DSA:3.30.110.60 2 76 6.9E-13 T 01-11-2018 IPR035920 YhbY-like superfamily AFULGI_00023380 13f87b980b2183b3ce3b455261fd4ad7 76 ProDom PD010559 RNA-BINDING YHBY UPF0044 PREDICTED RNA RIBOSOMAL CONTAINING KH BINDING DOMAIN 8 76 1.0E-7 T 01-11-2018 IPR001890 RNA-binding, CRM domain GO:0003723 AFULGI_00023380 13f87b980b2183b3ce3b455261fd4ad7 76 Pfam PF01985 CRS1 / YhbY (CRM) domain 8 74 5.0E-10 T 01-11-2018 IPR001890 RNA-binding, CRM domain GO:0003723 AFULGI_00023380 13f87b980b2183b3ce3b455261fd4ad7 76 SUPERFAMILY SSF75471 7 74 3.53E-12 T 01-11-2018 IPR035920 YhbY-like superfamily AFULGI_00024140 a04e2f5f49d1662a49ee0d660e538872 105 Gene3D G3DSA:3.40.30.10 1 104 1.2E-34 T 01-11-2018 AFULGI_00024140 a04e2f5f49d1662a49ee0d660e538872 105 PRINTS PR00421 Thioredoxin family signature 19 27 1.0E-7 T 01-11-2018 AFULGI_00024140 a04e2f5f49d1662a49ee0d660e538872 105 PRINTS PR00421 Thioredoxin family signature 67 78 1.0E-7 T 01-11-2018 AFULGI_00024140 a04e2f5f49d1662a49ee0d660e538872 105 PRINTS PR00421 Thioredoxin family signature 27 36 1.0E-7 T 01-11-2018 AFULGI_00024140 a04e2f5f49d1662a49ee0d660e538872 105 SUPERFAMILY SSF52833 4 103 2.5E-37 T 01-11-2018 IPR036249 Thioredoxin-like superfamily AFULGI_00024140 a04e2f5f49d1662a49ee0d660e538872 105 PIRSF PIRSF000077 1 103 4.3E-35 T 01-11-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 AFULGI_00024140 a04e2f5f49d1662a49ee0d660e538872 105 TIGRFAM TIGR01068 thioredoxin: thioredoxin 5 102 2.4E-39 T 01-11-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 AFULGI_00024140 a04e2f5f49d1662a49ee0d660e538872 105 Pfam PF00085 Thioredoxin 3 101 2.7E-29 T 01-11-2018 IPR013766 Thioredoxin domain GO:0045454 AFULGI_00024740 4f3e14925c6d94cd3686a7eb7ee42f88 228 PIRSF PIRSF038959 3 101 4.4E-12 T 01-11-2018 IPR026272 Immunity protein SdpI AFULGI_00024740 4f3e14925c6d94cd3686a7eb7ee42f88 228 PIRSF PIRSF038959 117 224 7.7E-7 T 01-11-2018 IPR026272 Immunity protein SdpI AFULGI_00024740 4f3e14925c6d94cd3686a7eb7ee42f88 228 Pfam PF07853 Protein of unknown function (DUF1648) 130 175 6.9E-15 T 01-11-2018 IPR012867 Domain of unknown function DUF1648 AFULGI_00024740 4f3e14925c6d94cd3686a7eb7ee42f88 228 Pfam PF13630 SdpI/YhfL protein family 25 91 9.6E-13 T 01-11-2018 IPR025962 SdpI/YhfL protein family AFULGI_00008690 46e4a809dd40fd8aa0c8705e68b385aa 358 PIRSF PIRSF019205 8 358 9.1E-159 T 01-11-2018 IPR012443 Protein of unknown function DUF1646 AFULGI_00008690 46e4a809dd40fd8aa0c8705e68b385aa 358 Pfam PF07854 Protein of unknown function (DUF1646) 15 358 4.6E-162 T 01-11-2018 IPR012443 Protein of unknown function DUF1646 AFULGI_00005990 c07f567d64a59bccf137252d6883dd8a 280 Gene3D G3DSA:1.10.10.10 202 274 2.2E-5 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00003370 015204cb76445bc991f59648a6e1feb2 542 SUPERFAMILY SSF52540 143 470 3.49E-59 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00003370 015204cb76445bc991f59648a6e1feb2 542 Pfam PF00437 Type II/IV secretion system protein 164 408 2.3E-52 T 01-11-2018 IPR001482 Type II/IV secretion system protein AFULGI_00003370 015204cb76445bc991f59648a6e1feb2 542 Gene3D G3DSA:3.30.450.380 35 258 7.3E-68 T 01-11-2018 AFULGI_00003370 015204cb76445bc991f59648a6e1feb2 542 Gene3D G3DSA:3.40.50.300 260 540 3.4E-105 T 01-11-2018 AFULGI_00000700 c407dbbd52a22499d397c1bfed5d0086 410 Gene3D G3DSA:3.90.1640.30 6 242 3.9E-11 T 01-11-2018 AFULGI_00000700 c407dbbd52a22499d397c1bfed5d0086 410 SUPERFAMILY SSF64182 4 405 9.31E-40 T 01-11-2018 IPR038763 DHH phosphoesterase superfamily AFULGI_00001990 8948919d2f57f81a31b309923d9ab523 237 SUPERFAMILY SSF46785 2 90 6.61E-13 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00001990 8948919d2f57f81a31b309923d9ab523 237 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 8 75 3.3E-26 T 01-11-2018 IPR002831 Transcription regulator TrmB, N-terminal AFULGI_00001990 8948919d2f57f81a31b309923d9ab523 237 Gene3D G3DSA:1.10.10.10 1 98 1.4E-27 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00005160 7b90b4ca9388263747ab5a36e236f05d 366 SUPERFAMILY SSF46548 5 91 8.37E-18 T 01-11-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 AFULGI_00005160 7b90b4ca9388263747ab5a36e236f05d 366 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 60 71 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFULGI_00005160 7b90b4ca9388263747ab5a36e236f05d 366 Pfam PF02754 Cysteine-rich domain 133 215 3.6E-19 T 01-11-2018 IPR004017 Cysteine-rich domain AFULGI_00005160 7b90b4ca9388263747ab5a36e236f05d 366 Pfam PF02754 Cysteine-rich domain 255 340 2.2E-20 T 01-11-2018 IPR004017 Cysteine-rich domain AFULGI_00005160 7b90b4ca9388263747ab5a36e236f05d 366 Gene3D G3DSA:3.30.70.3270 2 99 2.1E-7 T 01-11-2018 AFULGI_00005160 7b90b4ca9388263747ab5a36e236f05d 366 Pfam PF13534 4Fe-4S dicluster domain 9 74 9.6E-11 T 01-11-2018 AFULGI_00005290 213ef683e4f30f3faa22d6f1695dcc59 277 TIGRFAM TIGR01920 Shik_kin_archae: shikimate kinase 5 256 1.5E-98 T 01-11-2018 IPR010189 Shikimate kinase, archaea GO:0004765|GO:0005737|GO:0009073 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 AFULGI_00005290 213ef683e4f30f3faa22d6f1695dcc59 277 SUPERFAMILY SSF54211 3 144 2.66E-18 T 01-11-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFULGI_00005290 213ef683e4f30f3faa22d6f1695dcc59 277 Gene3D G3DSA:3.30.230.10 18 148 7.4E-17 T 01-11-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AFULGI_00005290 213ef683e4f30f3faa22d6f1695dcc59 277 Hamap MF_00370 Shikimate kinase [aroK]. 1 277 87.12 T 01-11-2018 IPR010189 Shikimate kinase, archaea GO:0004765|GO:0005737|GO:0009073 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 AFULGI_00005290 213ef683e4f30f3faa22d6f1695dcc59 277 Pfam PF00288 GHMP kinases N terminal domain 66 134 1.3E-10 T 01-11-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 AFULGI_00005290 213ef683e4f30f3faa22d6f1695dcc59 277 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 72 83 - T 01-11-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 AFULGI_00005290 213ef683e4f30f3faa22d6f1695dcc59 277 PIRSF PIRSF005758 1 269 5.3E-100 T 01-11-2018 IPR010189 Shikimate kinase, archaea GO:0004765|GO:0005737|GO:0009073 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 AFULGI_00012030 a5907d148c42860f59edd3b277bfe0c4 153 SUPERFAMILY SSF52954 3 82 4.32E-19 T 01-11-2018 AFULGI_00012030 a5907d148c42860f59edd3b277bfe0c4 153 Hamap MF_00699 Probable Brix domain-containing ribosomal biogenesis protein. 2 151 27.104 T 01-11-2018 IPR023548 Probable Brix domain-containing ribosomal biogenesis protein AFULGI_00012030 a5907d148c42860f59edd3b277bfe0c4 153 SMART SM00879 3 148 1.6E-4 T 01-11-2018 IPR007109 Brix domain AFULGI_00012030 a5907d148c42860f59edd3b277bfe0c4 153 Gene3D G3DSA:3.40.50.10480 1 139 4.5E-27 T 01-11-2018 AFULGI_00005570 6ddaad62cf4feb436f1256a87352d5cb 477 Pfam PF02754 Cysteine-rich domain 359 451 5.9E-20 T 01-11-2018 IPR004017 Cysteine-rich domain AFULGI_00005570 6ddaad62cf4feb436f1256a87352d5cb 477 SUPERFAMILY SSF46548 57 169 6.8E-14 T 01-11-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 AFULGI_00005570 6ddaad62cf4feb436f1256a87352d5cb 477 Pfam PF13183 4Fe-4S dicluster domain 68 154 2.2E-9 T 01-11-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFULGI_00005570 6ddaad62cf4feb436f1256a87352d5cb 477 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 141 152 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFULGI_00009580 1b7b71f261a8ea8167a13a9fd67d185f 457 SUPERFAMILY SSF56235 2 245 2.66E-65 T 01-11-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFULGI_00009580 1b7b71f261a8ea8167a13a9fd67d185f 457 Gene3D G3DSA:3.60.20.10 2 448 4.3E-159 T 01-11-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFULGI_00009580 1b7b71f261a8ea8167a13a9fd67d185f 457 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 1 446 48.55 T 01-11-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 AFULGI_00009580 1b7b71f261a8ea8167a13a9fd67d185f 457 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 2 447 5.4E-172 T 01-11-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 AFULGI_00009580 1b7b71f261a8ea8167a13a9fd67d185f 457 SUPERFAMILY SSF53271 239 453 1.78E-72 T 01-11-2018 IPR029057 Phosphoribosyltransferase-like AFULGI_00009580 1b7b71f261a8ea8167a13a9fd67d185f 457 Pfam PF00156 Phosphoribosyl transferase domain 275 373 3.0E-7 T 01-11-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 AFULGI_00009580 1b7b71f261a8ea8167a13a9fd67d185f 457 Pfam PF13537 Glutamine amidotransferase domain 83 202 2.7E-20 T 01-11-2018 IPR017932 Glutamine amidotransferase type 2 domain AFULGI_00009580 1b7b71f261a8ea8167a13a9fd67d185f 457 PIRSF PIRSF000485 1 456 3.1E-180 T 01-11-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 AFULGI_00009580 1b7b71f261a8ea8167a13a9fd67d185f 457 Gene3D G3DSA:3.40.50.2020 263 427 4.3E-159 T 01-11-2018 AFULGI_00010620 3e95be567991a40e43c8d9db77b7ce3e 205 SUPERFAMILY SSF53098 5 182 7.21E-39 T 01-11-2018 IPR012337 Ribonuclease H-like superfamily AFULGI_00010620 3e95be567991a40e43c8d9db77b7ce3e 205 SMART SM00479 9 180 8.6E-45 T 01-11-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III AFULGI_00010620 3e95be567991a40e43c8d9db77b7ce3e 205 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 3 203 5.6E-75 T 01-11-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFULGI_00010620 3e95be567991a40e43c8d9db77b7ce3e 205 Gene3D G3DSA:3.30.420.10 4 178 3.7E-36 T 01-11-2018 IPR036397 Ribonuclease H superfamily GO:0003676 AFULGI_00010620 3e95be567991a40e43c8d9db77b7ce3e 205 Pfam PF00929 Exonuclease 12 171 6.5E-35 T 01-11-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III AFULGI_00011270 165c595a965472e68ced39083d11fdc2 443 Gene3D G3DSA:3.60.21.10 1 266 7.2E-91 T 01-11-2018 IPR029052 Metallo-dependent phosphatase-like AFULGI_00011270 165c595a965472e68ced39083d11fdc2 443 Pfam PF00149 Calcineurin-like phosphoesterase 1 204 7.9E-16 T 01-11-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 AFULGI_00011270 165c595a965472e68ced39083d11fdc2 443 SUPERFAMILY SSF56300 1 325 8.62E-56 T 01-11-2018 AFULGI_00011270 165c595a965472e68ced39083d11fdc2 443 Gene3D G3DSA:3.30.110.80 225 315 7.2E-91 T 01-11-2018 AFULGI_00011270 165c595a965472e68ced39083d11fdc2 443 Hamap MF_02044 DNA double-strand break repair protein Mre11 [mre11]. 1 401 24.161 T 01-11-2018 IPR032885 DNA double-strand break repair protein Mre11, archaea-type GO:0006302 AFULGI_00017910 cce8f22f3b2fcdd45589b4f335ea065c 251 Pfam PF12697 Alpha/beta hydrolase family 27 241 4.3E-16 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 AFULGI_00017910 cce8f22f3b2fcdd45589b4f335ea065c 251 Gene3D G3DSA:3.40.50.1820 1 249 2.1E-79 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold AFULGI_00017910 cce8f22f3b2fcdd45589b4f335ea065c 251 SUPERFAMILY SSF53474 18 247 1.94E-42 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold AFULGI_00017910 cce8f22f3b2fcdd45589b4f335ea065c 251 PRINTS PR00111 Alpha/beta hydrolase fold signature 85 98 6.2E-8 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 AFULGI_00017910 cce8f22f3b2fcdd45589b4f335ea065c 251 PRINTS PR00111 Alpha/beta hydrolase fold signature 99 112 6.2E-8 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 AFULGI_00017910 cce8f22f3b2fcdd45589b4f335ea065c 251 PRINTS PR00111 Alpha/beta hydrolase fold signature 192 206 6.2E-8 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 AFULGI_00018140 961cfd5ac6eba93233fa6efba50da669 285 Pfam PF01925 Sulfite exporter TauE/SafE 15 275 8.2E-36 T 01-11-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 AFULGI_00015450 adf662eab52befdd48e0232a7337ebd0 159 Pfam PF01927 Mut7-C RNAse domain 4 153 1.1E-35 T 01-11-2018 IPR002782 Mut7-C RNAse domain AFULGI_00003230 03d7f7be690d2696e403d9c8a8944672 66 SUPERFAMILY SSF51182 1 65 2.02E-18 T 01-11-2018 IPR011051 RmlC-like cupin domain superfamily AFULGI_00003230 03d7f7be690d2696e403d9c8a8944672 66 Gene3D G3DSA:2.60.120.10 1 64 7.0E-10 T 01-11-2018 IPR014710 RmlC-like jelly roll fold AFULGI_00003230 03d7f7be690d2696e403d9c8a8944672 66 Pfam PF01050 Mannose-6-phosphate isomerase 1 61 2.5E-24 T 01-11-2018 IPR001538 Mannose-6-phosphate isomerase, type II, C-terminal GO:0005976|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 AFULGI_00026070 d5c42c975a3b8876168fe46176162049 365 SUPERFAMILY SSF55931 1 341 3.92E-47 T 01-11-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 AFULGI_00026070 d5c42c975a3b8876168fe46176162049 365 Gene3D G3DSA:3.30.590.20 1 349 1.4E-56 T 01-11-2018 AFULGI_00026070 d5c42c975a3b8876168fe46176162049 365 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 13 284 7.7E-73 T 01-11-2018 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 AFULGI_00019960 aa7442094cb3b0012c682abf72900a16 175 Pfam PF01402 Ribbon-helix-helix protein, copG family 6 43 5.1E-11 T 01-11-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 AFULGI_00018750 4690587582178ce55ab4b628c9884e1a 86 Gene3D G3DSA:3.10.20.30 1 86 1.1E-27 T 01-11-2018 IPR012675 Beta-grasp domain superfamily AFULGI_00018750 4690587582178ce55ab4b628c9884e1a 86 SUPERFAMILY SSF54285 2 86 9.53E-24 T 01-11-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp AFULGI_00018750 4690587582178ce55ab4b628c9884e1a 86 TIGRFAM TIGR01687 moaD_arch: MoaD family protein 2 86 1.0E-31 T 01-11-2018 IPR010038 MoaD, archaeal-type AFULGI_00018750 4690587582178ce55ab4b628c9884e1a 86 Pfam PF02597 ThiS family 4 86 1.1E-19 T 01-11-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 AFULGI_00014950 20ea33efe4c410ae33b0dd97a3a62c8e 299 SUPERFAMILY SSF53098 125 270 1.01E-28 T 01-11-2018 IPR012337 Ribonuclease H-like superfamily AFULGI_00014950 20ea33efe4c410ae33b0dd97a3a62c8e 299 Gene3D G3DSA:3.30.420.10 124 290 8.5E-23 T 01-11-2018 IPR036397 Ribonuclease H superfamily GO:0003676 AFULGI_00014950 20ea33efe4c410ae33b0dd97a3a62c8e 299 SUPERFAMILY SSF46689 6 109 3.72E-14 T 01-11-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFULGI_00014950 20ea33efe4c410ae33b0dd97a3a62c8e 299 Pfam PF13518 Helix-turn-helix domain 12 58 6.9E-9 T 01-11-2018 AFULGI_00014950 20ea33efe4c410ae33b0dd97a3a62c8e 299 Pfam PF00665 Integrase core domain 129 245 1.5E-25 T 01-11-2018 IPR001584 Integrase, catalytic core GO:0015074 AFULGI_00021850 d320f31810b78456c4801cd364c7fc1f 256 SUPERFAMILY SSF75217 2 248 9.59E-47 T 01-11-2018 IPR029028 Alpha/beta knot methyltransferases AFULGI_00021850 d320f31810b78456c4801cd364c7fc1f 256 Gene3D G3DSA:3.40.1280.10 4 247 2.2E-73 T 01-11-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal AFULGI_00021850 d320f31810b78456c4801cd364c7fc1f 256 SUPERFAMILY SSF50249 89 159 1.03E-14 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold AFULGI_00021850 d320f31810b78456c4801cd364c7fc1f 256 Pfam PF02598 Putative RNA methyltransferase 2 245 8.3E-56 T 01-11-2018 IPR003750 Putative RNA methyltransferase AFULGI_00021850 d320f31810b78456c4801cd364c7fc1f 256 Gene3D G3DSA:2.40.50.140 95 156 2.2E-73 T 01-11-2018 AFULGI_00020290 c6d8eaa247f9f2739644d641305a8ecd 85 Gene3D G3DSA:3.30.1120.40 1 85 2.1E-34 T 01-11-2018 IPR036751 Stage V sporulation protein G superfamily GO:0030435 AFULGI_00020290 c6d8eaa247f9f2739644d641305a8ecd 85 SUPERFAMILY SSF160537 3 84 4.19E-30 T 01-11-2018 IPR036751 Stage V sporulation protein G superfamily GO:0030435 AFULGI_00020290 c6d8eaa247f9f2739644d641305a8ecd 85 Hamap MF_00819 Putative septation protein SpoVG [spoVG]. 2 85 23.777 T 01-11-2018 IPR007170 Stage V sporulation protein G GO:0030435 AFULGI_00020290 c6d8eaa247f9f2739644d641305a8ecd 85 Pfam PF04026 SpoVG 3 83 1.1E-31 T 01-11-2018 IPR007170 Stage V sporulation protein G GO:0030435 AFULGI_00024680 1ce47d510a4b7dfe18ad49fc8553734b 235 Hamap MF_00681 (5-formylfuran-3-yl)methyl phosphate synthase [mfnB]. 1 233 46.348 T 01-11-2018 IPR035081 (5-formylfuran-3-yl)methyl phosphate synthase, archaea GO:0016830|GO:2001120 KEGG: 00680+4.2.3.153|MetaCyc: PWY-5254 AFULGI_00024680 1ce47d510a4b7dfe18ad49fc8553734b 235 SUPERFAMILY SSF51569 8 122 1.5E-11 T 01-11-2018 AFULGI_00024680 1ce47d510a4b7dfe18ad49fc8553734b 235 SUPERFAMILY SSF51366 80 215 3.45E-5 T 01-11-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 AFULGI_00024680 1ce47d510a4b7dfe18ad49fc8553734b 235 PIRSF PIRSF015957 1 235 1.5E-122 T 01-11-2018 IPR007565 (5-formylfuran-3-yl)methyl phosphate synthase KEGG: 00680+4.2.3.153|MetaCyc: PWY-5254 AFULGI_00024680 1ce47d510a4b7dfe18ad49fc8553734b 235 Pfam PF04476 4-HFC-P synthase 3 229 2.9E-89 T 01-11-2018 IPR007565 (5-formylfuran-3-yl)methyl phosphate synthase KEGG: 00680+4.2.3.153|MetaCyc: PWY-5254 AFULGI_00009110 7e87d2ab54d12653716a0106f2d9ac72 297 Pfam PF02653 Branched-chain amino acid transport system / permease component 12 282 1.1E-49 T 01-11-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 AFULGI_00000890 b2cd24e7654219d353af7f8596f24f96 324 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 108 321 2.8E-63 T 01-11-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 AFULGI_00000890 b2cd24e7654219d353af7f8596f24f96 324 SUPERFAMILY SSF56529 109 322 8.5E-69 T 01-11-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 AFULGI_00000890 b2cd24e7654219d353af7f8596f24f96 324 Gene3D G3DSA:3.90.850.10 37 315 1.2E-75 T 01-11-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 AFULGI_00000090 17306b6ab013112d6d939b5338d7ca4e 239 Gene3D G3DSA:3.40.50.280 108 238 1.7E-43 T 01-11-2018 AFULGI_00000090 17306b6ab013112d6d939b5338d7ca4e 239 SMART SM01018 31 113 3.4E-24 T 01-11-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFULGI_00000090 17306b6ab013112d6d939b5338d7ca4e 239 SUPERFAMILY SSF47644 30 112 7.32E-17 T 01-11-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFULGI_00000090 17306b6ab013112d6d939b5338d7ca4e 239 Gene3D G3DSA:1.10.1240.10 32 107 8.1E-24 T 01-11-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFULGI_00000090 17306b6ab013112d6d939b5338d7ca4e 239 Pfam PF02607 B12 binding domain 35 105 6.4E-13 T 01-11-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFULGI_00000090 17306b6ab013112d6d939b5338d7ca4e 239 SUPERFAMILY SSF52242 99 237 2.62E-40 T 01-11-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 AFULGI_00000090 17306b6ab013112d6d939b5338d7ca4e 239 Pfam PF02310 B12 binding domain 119 225 6.8E-26 T 01-11-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 AFULGI_00000480 954ec794601aab2bc1e524be408b0628 132 Pfam PF01989 Protein of unknown function DUF126 24 102 3.0E-32 T 01-11-2018 IPR002840 Aconitase X swivel domain, putative AFULGI_00000480 954ec794601aab2bc1e524be408b0628 132 Gene3D G3DSA:3.50.30.10 1 132 3.6E-58 T 01-11-2018 AFULGI_00000480 954ec794601aab2bc1e524be408b0628 132 Hamap MF_00078 UPF0107 protein . 2 131 32.206 T 01-11-2018 IPR020794 Aconitase X subunit 2, archaeal, putative AFULGI_00000480 954ec794601aab2bc1e524be408b0628 132 SUPERFAMILY SSF52016 3 130 3.3E-44 T 01-11-2018 AFULGI_00000480 954ec794601aab2bc1e524be408b0628 132 PIRSF PIRSF004966 1 132 3.1E-54 T 01-11-2018 IPR012016 Aconitase X subunit 2, putative AFULGI_00003290 4426169dd0846f8818a989532ac7aade 160 PIRSF PIRSF005785 1 160 1.2E-57 T 01-11-2018 IPR012091 Peptidase M54, archaemetzincin, archaeal/bacterial GO:0006508|GO:0008237|GO:0008270 AFULGI_00003290 4426169dd0846f8818a989532ac7aade 160 Hamap MF_01842 Archaemetzincin [amzA]. 1 159 33.373 T 01-11-2018 IPR012091 Peptidase M54, archaemetzincin, archaeal/bacterial GO:0006508|GO:0008237|GO:0008270 AFULGI_00003290 4426169dd0846f8818a989532ac7aade 160 SUPERFAMILY SSF55486 64 151 1.2E-12 T 01-11-2018 AFULGI_00003290 4426169dd0846f8818a989532ac7aade 160 Gene3D G3DSA:3.40.390.10 1 160 2.1E-64 T 01-11-2018 IPR024079 Metallopeptidase, catalytic domain superfamily GO:0008237 AFULGI_00003290 4426169dd0846f8818a989532ac7aade 160 Pfam PF07998 Peptidase family M54 64 159 2.1E-31 T 01-11-2018 IPR012962 Peptidase M54, archaemetzincin GO:0008270 AFULGI_00008730 002f650100d51f50a3e4bfa3b189855a 314 Pfam PF01384 Phosphate transporter family 17 302 4.3E-54 T 01-11-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 AFULGI_00011890 00d11e19bcd2a3614d004947478ad786 85 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 6 84 3.6E-10 T 01-11-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family AFULGI_00011890 00d11e19bcd2a3614d004947478ad786 85 TIGRFAM TIGR02385 RelE_StbE: addiction module toxin, RelE/StbE family 6 84 1.2E-12 T 01-11-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family AFULGI_00011890 00d11e19bcd2a3614d004947478ad786 85 TIGRFAM TIGR00053 TIGR00053: addiction module toxin component, YafQ family 2 85 2.3E-27 T 01-11-2018 IPR004386 Toxin-antitoxin system, YafQ-like toxin AFULGI_00011890 00d11e19bcd2a3614d004947478ad786 85 Gene3D G3DSA:3.30.2310.20 2 85 2.8E-11 T 01-11-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily AFULGI_00011890 00d11e19bcd2a3614d004947478ad786 85 SUPERFAMILY SSF143011 1 84 2.49E-15 T 01-11-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily AFULGI_00002070 a01f4adc163ffe786a434c4f072183ce 224 ProSitePatterns PS00211 ABC transporters family signature. 128 142 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFULGI_00002070 a01f4adc163ffe786a434c4f072183ce 224 SUPERFAMILY SSF52540 2 215 3.26E-57 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00002070 a01f4adc163ffe786a434c4f072183ce 224 SMART SM00382 28 213 9.0E-11 T 01-11-2018 IPR003593 AAA+ ATPase domain AFULGI_00002070 a01f4adc163ffe786a434c4f072183ce 224 Gene3D G3DSA:3.40.50.300 2 224 1.4E-56 T 01-11-2018 AFULGI_00002070 a01f4adc163ffe786a434c4f072183ce 224 Pfam PF00005 ABC transporter 19 155 2.5E-31 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFULGI_00010890 605ae306530708c1c8927d763227c2fe 651 Gene3D G3DSA:1.20.81.30 434 545 1.1E-10 T 01-11-2018 AFULGI_00010890 605ae306530708c1c8927d763227c2fe 651 Pfam PF00482 Type II secretion system (T2SS), protein F 147 273 4.3E-23 T 01-11-2018 IPR018076 Type II secretion system F domain AFULGI_00010890 605ae306530708c1c8927d763227c2fe 651 Pfam PF00482 Type II secretion system (T2SS), protein F 439 564 1.5E-21 T 01-11-2018 IPR018076 Type II secretion system F domain AFULGI_00005770 e03bfb84208c7614ae562fc841b00c48 94 SUPERFAMILY SSF75169 2 94 3.53E-18 T 01-11-2018 IPR027396 DsrEFH-like AFULGI_00005770 e03bfb84208c7614ae562fc841b00c48 94 Pfam PF02635 DsrE/DsrF-like family 3 94 4.2E-15 T 01-11-2018 IPR003787 Sulphur relay, DsrE/F-like protein AFULGI_00005770 e03bfb84208c7614ae562fc841b00c48 94 Gene3D G3DSA:3.40.1260.10 1 94 1.4E-26 T 01-11-2018 IPR027396 DsrEFH-like AFULGI_00006380 398d62081a65d8f18ebe20b637bf11cd 86 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 4 48 2.1E-12 T 01-11-2018 IPR007159 SpoVT-AbrB domain GO:0003677 AFULGI_00006380 398d62081a65d8f18ebe20b637bf11cd 86 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 3 44 3.6E-17 T 01-11-2018 IPR007159 SpoVT-AbrB domain GO:0003677 AFULGI_00006380 398d62081a65d8f18ebe20b637bf11cd 86 SUPERFAMILY SSF89447 1 45 5.41E-13 T 01-11-2018 IPR037914 SpoVT-AbrB domain superfamily AFULGI_00006380 398d62081a65d8f18ebe20b637bf11cd 86 SMART SM00966 4 49 3.6E-15 T 01-11-2018 IPR007159 SpoVT-AbrB domain GO:0003677 AFULGI_00006380 398d62081a65d8f18ebe20b637bf11cd 86 Gene3D G3DSA:2.10.260.10 3 42 6.2E-14 T 01-11-2018 AFULGI_00006340 b89e5578002764b375a78d02240a4593 426 SUPERFAMILY SSF160980 15 420 7.45E-37 T 01-11-2018 AFULGI_00006340 b89e5578002764b375a78d02240a4593 426 Pfam PF09455 CRISPR-associated (Cas) DxTHG family 11 392 3.3E-8 T 01-11-2018 IPR019016 CRISPR-associated DxTHG protein AFULGI_00006340 b89e5578002764b375a78d02240a4593 426 Gene3D G3DSA:3.40.50.10640 6 222 1.4E-6 T 01-11-2018 AFULGI_00006340 b89e5578002764b375a78d02240a4593 426 Gene3D G3DSA:1.10.3740.10 296 423 3.6E-5 T 01-11-2018 IPR027419 CRISPR-associated protein Csx1, C-terminal AFULGI_00012810 5f020c4c7b0b320f9c155a35388cd42c 211 PRINTS PR00449 Transforming protein P21 ras signature 24 45 3.1E-10 T 01-11-2018 AFULGI_00012810 5f020c4c7b0b320f9c155a35388cd42c 211 PRINTS PR00449 Transforming protein P21 ras signature 158 171 3.1E-10 T 01-11-2018 AFULGI_00012810 5f020c4c7b0b320f9c155a35388cd42c 211 PRINTS PR00449 Transforming protein P21 ras signature 73 95 3.1E-10 T 01-11-2018 AFULGI_00012810 5f020c4c7b0b320f9c155a35388cd42c 211 PRINTS PR00449 Transforming protein P21 ras signature 188 210 3.1E-10 T 01-11-2018 AFULGI_00012810 5f020c4c7b0b320f9c155a35388cd42c 211 Gene3D G3DSA:3.40.50.300 18 209 1.3E-30 T 01-11-2018 AFULGI_00012810 5f020c4c7b0b320f9c155a35388cd42c 211 Pfam PF01926 50S ribosome-binding GTPase 25 168 3.3E-15 T 01-11-2018 IPR006073 GTP binding domain GO:0005525 AFULGI_00012810 5f020c4c7b0b320f9c155a35388cd42c 211 SUPERFAMILY SSF52540 19 201 1.01E-29 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00012810 5f020c4c7b0b320f9c155a35388cd42c 211 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 23 206 6.3E-19 T 01-11-2018 IPR005225 Small GTP-binding protein domain GO:0005525 AFULGI_00017270 fba2d3be863d42700d16ffada4e220d0 153 PIRSF PIRSF005859 1 153 2.5E-45 T 01-11-2018 IPR004307 TspO/MBR-related protein GO:0016021 AFULGI_00017270 fba2d3be863d42700d16ffada4e220d0 153 Gene3D G3DSA:1.20.1260.100 1 153 4.6E-47 T 01-11-2018 IPR038330 TspO/MBR-related superfamily AFULGI_00017270 fba2d3be863d42700d16ffada4e220d0 153 Pfam PF03073 TspO/MBR family 9 149 9.3E-42 T 01-11-2018 IPR004307 TspO/MBR-related protein GO:0016021 AFULGI_00026720 498309b850358e90ff04a17478263c82 145 Gene3D G3DSA:1.20.1290.10 3 144 8.8E-25 T 01-11-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 AFULGI_00026720 498309b850358e90ff04a17478263c82 145 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 44 93 5.0E-18 T 01-11-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 AFULGI_00026720 498309b850358e90ff04a17478263c82 145 SUPERFAMILY SSF69118 13 143 4.97E-30 T 01-11-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 AFULGI_00026720 498309b850358e90ff04a17478263c82 145 Pfam PF02627 Carboxymuconolactone decarboxylase family 27 96 1.4E-10 T 01-11-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 AFULGI_00006190 ee8a79a1a42334f6f3d1aefc0f69d25a 525 Pfam PF01935 Domain of unknown function DUF87 138 349 1.4E-35 T 01-11-2018 IPR002789 Helicase HerA, central domain AFULGI_00006190 ee8a79a1a42334f6f3d1aefc0f69d25a 525 Gene3D G3DSA:3.40.50.300 122 253 1.3E-19 T 01-11-2018 AFULGI_00006190 ee8a79a1a42334f6f3d1aefc0f69d25a 525 Gene3D G3DSA:3.40.50.300 270 490 4.7E-56 T 01-11-2018 AFULGI_00006190 ee8a79a1a42334f6f3d1aefc0f69d25a 525 SUPERFAMILY SSF52540 129 486 1.12E-44 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00024250 d9310cee1c8e73991f3b6c374f477bfe 234 SMART SM00849 18 203 7.3E-14 T 01-11-2018 IPR001279 Metallo-beta-lactamase AFULGI_00024250 d9310cee1c8e73991f3b6c374f477bfe 234 Pfam PF00753 Metallo-beta-lactamase superfamily 18 203 6.1E-18 T 01-11-2018 IPR001279 Metallo-beta-lactamase AFULGI_00024250 d9310cee1c8e73991f3b6c374f477bfe 234 Gene3D G3DSA:3.60.15.10 2 234 6.4E-49 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFULGI_00024250 d9310cee1c8e73991f3b6c374f477bfe 234 SUPERFAMILY SSF56281 2 234 3.54E-47 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFULGI_00009920 ae73079d24017790fd861296865eee94 494 SUPERFAMILY SSF53067 1 393 5.1E-14 T 01-11-2018 AFULGI_00009920 ae73079d24017790fd861296865eee94 494 Pfam PF01968 Hydantoinase/oxoprolinase 164 345 6.2E-21 T 01-11-2018 IPR002821 Hydantoinase A/oxoprolinase GO:0016787 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 AFULGI_00009920 ae73079d24017790fd861296865eee94 494 Pfam PF05378 Hydantoinase/oxoprolinase N-terminal region 81 144 2.0E-4 T 01-11-2018 IPR008040 Hydantoinaseoxoprolinase, N-terminal Reactome: R-HSA-174403|Reactome: R-HSA-5578998 AFULGI_00009920 ae73079d24017790fd861296865eee94 494 Pfam PF05378 Hydantoinase/oxoprolinase N-terminal region 3 42 2.7E-5 T 01-11-2018 IPR008040 Hydantoinaseoxoprolinase, N-terminal Reactome: R-HSA-174403|Reactome: R-HSA-5578998 AFULGI_00014390 80baccd1416d10c8da6a9436ec1b94b6 453 Gene3D G3DSA:3.50.50.60 3 342 2.1E-89 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFULGI_00014390 80baccd1416d10c8da6a9436ec1b94b6 453 Pfam PF04324 BFD-like [2Fe-2S] binding domain 389 437 4.6E-8 T 01-11-2018 IPR007419 BFD-like [2Fe-2S]-binding domain AFULGI_00014390 80baccd1416d10c8da6a9436ec1b94b6 453 Gene3D G3DSA:3.30.9.10 85 310 2.1E-89 T 01-11-2018 AFULGI_00014390 80baccd1416d10c8da6a9436ec1b94b6 453 Pfam PF01266 FAD dependent oxidoreductase 3 347 2.4E-55 T 01-11-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 AFULGI_00014390 80baccd1416d10c8da6a9436ec1b94b6 453 Gene3D G3DSA:1.10.10.1100 389 442 2.7E-8 T 01-11-2018 AFULGI_00014390 80baccd1416d10c8da6a9436ec1b94b6 453 SUPERFAMILY SSF51905 2 352 4.14E-45 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFULGI_00012170 a848327020c6ebbed8e9966887a26b27 165 Gene3D G3DSA:3.40.50.1440 1 165 7.9E-7 T 01-11-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 AFULGI_00012170 a848327020c6ebbed8e9966887a26b27 165 SUPERFAMILY SSF52490 1 107 1.78E-8 T 01-11-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 AFULGI_00002700 9e57365d056789d5fee8a098e8127117 967 Pfam PF05048 Periplasmic copper-binding protein (NosD) 67 292 4.8E-27 T 01-11-2018 IPR007742 Periplasmic copper-binding protein NosD, beta helix domain Reactome: R-HSA-8951664|Reactome: R-HSA-983168 AFULGI_00002700 9e57365d056789d5fee8a098e8127117 967 SMART SM00722 114 285 3.7E-7 T 01-11-2018 IPR006633 Carbohydrate-binding/sugar hydrolysis domain AFULGI_00002700 9e57365d056789d5fee8a098e8127117 967 SMART SM00710 163 184 1700.0 T 01-11-2018 IPR006626 Parallel beta-helix repeat AFULGI_00002700 9e57365d056789d5fee8a098e8127117 967 SMART SM00710 118 140 1300.0 T 01-11-2018 IPR006626 Parallel beta-helix repeat AFULGI_00002700 9e57365d056789d5fee8a098e8127117 967 SMART SM00710 141 162 130.0 T 01-11-2018 IPR006626 Parallel beta-helix repeat AFULGI_00002700 9e57365d056789d5fee8a098e8127117 967 SMART SM00710 197 220 5200.0 T 01-11-2018 IPR006626 Parallel beta-helix repeat AFULGI_00002700 9e57365d056789d5fee8a098e8127117 967 SMART SM00710 96 117 61.0 T 01-11-2018 IPR006626 Parallel beta-helix repeat AFULGI_00002700 9e57365d056789d5fee8a098e8127117 967 Pfam PF10342 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family 312 394 5.5E-11 T 01-11-2018 IPR018466 Kre9/Knh1 family AFULGI_00002700 9e57365d056789d5fee8a098e8127117 967 TIGRFAM TIGR04126 PGF_CTERM: PGF-CTERM archaeal protein-sorting signal 944 967 7.4E-8 T 01-11-2018 IPR026371 PGF-CTERM archaeal protein-sorting signal AFULGI_00002700 9e57365d056789d5fee8a098e8127117 967 SUPERFAMILY SSF51126 26 254 2.48E-15 T 01-11-2018 IPR011050 Pectin lyase fold/virulence factor AFULGI_00002700 9e57365d056789d5fee8a098e8127117 967 Gene3D G3DSA:2.160.20.10 20 222 4.4E-8 T 01-11-2018 IPR012334 Pectin lyase fold AFULGI_00003760 f537ba734237e7a42e33f25e9cd62429 470 SUPERFAMILY SSF51717 132 320 4.87E-14 T 01-11-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFULGI_00003760 f537ba734237e7a42e33f25e9cd62429 470 PIRSF PIRSF000376 1 470 1.2E-222 T 01-11-2018 IPR016218 Acetyl-CoA decarbonylase/synthase complex, gamma subunit GO:0005506|GO:0008168|GO:0046356 AFULGI_00003760 f537ba734237e7a42e33f25e9cd62429 470 Hamap MF_01136 Acetyl-CoA decarbonylase/synthase complex subunit gamma [cdhE]. 2 468 53.188 T 01-11-2018 IPR023427 Acetyl-CoA decarbonylase/synthase complex, gamma subunit, archaea GO:0006084|GO:0008168 AFULGI_00003760 f537ba734237e7a42e33f25e9cd62429 470 Pfam PF04060 Putative Fe-S cluster 13 45 1.8E-11 T 01-11-2018 IPR007202 4Fe-4S domain GO:0051536 AFULGI_00003760 f537ba734237e7a42e33f25e9cd62429 470 Gene3D G3DSA:3.20.20.20 69 338 7.4E-82 T 01-11-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFULGI_00003760 f537ba734237e7a42e33f25e9cd62429 470 Gene3D G3DSA:1.10.15.40 4 59 4.5E-15 T 01-11-2018 AFULGI_00003760 f537ba734237e7a42e33f25e9cd62429 470 Gene3D G3DSA:3.40.50.11600 339 467 1.2E-47 T 01-11-2018 AFULGI_00003760 f537ba734237e7a42e33f25e9cd62429 470 Pfam PF03599 CO dehydrogenase/acetyl-CoA synthase delta subunit 73 462 7.0E-165 T 01-11-2018 IPR016041 CO dehydrogenase/acetyl-CoA synthase delta subunit, TIM barrel AFULGI_00023520 36e6245746251463e6c211daa3297df6 83 Pfam PF14947 Winged helix-turn-helix 4 82 2.7E-26 T 01-11-2018 IPR038723 ArnR1-like, winged helix-turn-helix domain AFULGI_00023520 36e6245746251463e6c211daa3297df6 83 Gene3D G3DSA:1.10.10.10 2 83 2.2E-25 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00023520 36e6245746251463e6c211daa3297df6 83 SUPERFAMILY SSF46785 5 81 1.66E-11 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00019250 ac7b13b391b7b2b2b3b2df2f12431212 245 Gene3D G3DSA:3.30.1600.10 29 162 4.2E-103 T 01-11-2018 IPR026591 Sirtuin, catalytic core small domain superfamily AFULGI_00019250 ac7b13b391b7b2b2b3b2df2f12431212 245 Hamap MF_01121 NAD-dependent protein deacylase [cobB]. 13 242 60.452 T 01-11-2018 IPR027546 Sirtuin, class III GO:0036054|GO:0036055|GO:0070403 Reactome: R-HSA-2151201 AFULGI_00019250 ac7b13b391b7b2b2b3b2df2f12431212 245 Pfam PF02146 Sir2 family 20 192 3.0E-61 T 01-11-2018 IPR003000 Sirtuin family GO:0070403 AFULGI_00019250 ac7b13b391b7b2b2b3b2df2f12431212 245 Gene3D G3DSA:3.40.50.1220 11 236 4.2E-103 T 01-11-2018 AFULGI_00019250 ac7b13b391b7b2b2b3b2df2f12431212 245 SUPERFAMILY SSF52467 3 240 8.39E-91 T 01-11-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily AFULGI_00013610 79ef835672c627f94aec5523615f7412 632 Gene3D G3DSA:3.40.50.720 376 626 1.3E-75 T 01-11-2018 AFULGI_00013610 79ef835672c627f94aec5523615f7412 632 SUPERFAMILY SSF51395 2 362 4.4E-106 T 01-11-2018 AFULGI_00013610 79ef835672c627f94aec5523615f7412 632 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 375 600 3.9E-34 T 01-11-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFULGI_00013610 79ef835672c627f94aec5523615f7412 632 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 2 330 2.0E-69 T 01-11-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 AFULGI_00013610 79ef835672c627f94aec5523615f7412 632 Gene3D G3DSA:3.50.50.60 471 588 1.3E-75 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFULGI_00013610 79ef835672c627f94aec5523615f7412 632 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 580 596 1.4E-18 T 01-11-2018 AFULGI_00013610 79ef835672c627f94aec5523615f7412 632 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 377 396 1.4E-18 T 01-11-2018 AFULGI_00013610 79ef835672c627f94aec5523615f7412 632 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 459 477 1.4E-18 T 01-11-2018 AFULGI_00013610 79ef835672c627f94aec5523615f7412 632 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 497 515 1.4E-18 T 01-11-2018 AFULGI_00013610 79ef835672c627f94aec5523615f7412 632 SUPERFAMILY SSF51905 354 629 3.75E-50 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFULGI_00013610 79ef835672c627f94aec5523615f7412 632 Gene3D G3DSA:3.20.20.70 1 369 6.9E-125 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFULGI_00021770 028ef6c9da78e2802e87ac33f8bac411 57 Pfam PF00831 Ribosomal L29 protein 1 52 3.8E-12 T 01-11-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00021770 028ef6c9da78e2802e87ac33f8bac411 57 SUPERFAMILY SSF46561 1 52 1.96E-11 T 01-11-2018 IPR036049 Ribosomal protein L29/L35 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00021770 028ef6c9da78e2802e87ac33f8bac411 57 TIGRFAM TIGR00012 L29: ribosomal protein uL29 1 53 1.9E-17 T 01-11-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00021770 028ef6c9da78e2802e87ac33f8bac411 57 Gene3D G3DSA:1.10.287.310 1 56 1.3E-17 T 01-11-2018 AFULGI_00021770 028ef6c9da78e2802e87ac33f8bac411 57 ProSitePatterns PS00579 Ribosomal protein L29 signature. 32 46 - T 01-11-2018 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00021770 028ef6c9da78e2802e87ac33f8bac411 57 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 1 53 11.54 T 01-11-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00022110 1e18c4902996d6d19413f64acd92a2e6 257 SMART SM00730 34 257 1.7E-56 T 01-11-2018 IPR006639 Presenilin/signal peptide peptidase GO:0004190|GO:0016021 AFULGI_00022110 1e18c4902996d6d19413f64acd92a2e6 257 Pfam PF06550 Signal-peptide peptidase, presenilin aspartyl protease 8 256 3.3E-50 T 01-11-2018 IPR010545 Signal-peptide peptidase, presenilin aspartyl protease AFULGI_00027000 39c6c8906445976ef8c1d70c694dfe5d 322 Gene3D G3DSA:3.100.10.20 1 82 8.0E-32 T 01-11-2018 AFULGI_00027000 39c6c8906445976ef8c1d70c694dfe5d 322 TIGRFAM TIGR03641 cas1_HMARI: CRISPR-associated endonuclease Cas1, subtype I-B/HMARI/TNEAP 4 322 6.9E-147 T 01-11-2018 IPR019858 CRISPR-associated protein Cas1, HMARI/TNEAP subtype GO:0004520|GO:0043571|GO:0046872 AFULGI_00027000 39c6c8906445976ef8c1d70c694dfe5d 322 Hamap MF_01470 CRISPR-associated endonuclease Cas1 [cas1]. 2 307 28.588 T 01-11-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 AFULGI_00027000 39c6c8906445976ef8c1d70c694dfe5d 322 Pfam PF01867 CRISPR associated protein Cas1 6 277 1.2E-90 T 01-11-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 AFULGI_00027000 39c6c8906445976ef8c1d70c694dfe5d 322 Gene3D G3DSA:1.20.120.920 83 321 6.8E-76 T 01-11-2018 AFULGI_00027000 39c6c8906445976ef8c1d70c694dfe5d 322 TIGRFAM TIGR00287 cas1: CRISPR-associated endonuclease Cas1 7 317 3.2E-105 T 01-11-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 AFULGI_00004800 a3c419d9166d769e64e4dd2bfecd3b6f 320 SMART SM00966 8 53 6.6E-10 T 01-11-2018 IPR007159 SpoVT-AbrB domain GO:0003677 AFULGI_00004800 a3c419d9166d769e64e4dd2bfecd3b6f 320 SUPERFAMILY SSF89447 11 50 3.66E-6 T 01-11-2018 IPR037914 SpoVT-AbrB domain superfamily AFULGI_00004800 a3c419d9166d769e64e4dd2bfecd3b6f 320 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 10 47 2.6E-10 T 01-11-2018 IPR007159 SpoVT-AbrB domain GO:0003677 AFULGI_00004800 a3c419d9166d769e64e4dd2bfecd3b6f 320 SUPERFAMILY SSF109755 121 307 1.19E-7 T 01-11-2018 AFULGI_00004800 a3c419d9166d769e64e4dd2bfecd3b6f 320 Pfam PF01895 PhoU domain 134 224 5.5E-10 T 01-11-2018 IPR026022 PhoU domain AFULGI_00010520 d93a9def35c0f34953d850ac423ed03f 390 SUPERFAMILY SSF53822 35 387 7.66E-50 T 01-11-2018 IPR028082 Periplasmic binding protein-like I AFULGI_00010520 d93a9def35c0f34953d850ac423ed03f 390 Gene3D G3DSA:3.40.50.2300 35 353 3.1E-49 T 01-11-2018 AFULGI_00010520 d93a9def35c0f34953d850ac423ed03f 390 Pfam PF13458 Periplasmic binding protein 34 354 7.4E-39 T 01-11-2018 IPR028081 Leucine-binding protein domain AFULGI_00010520 d93a9def35c0f34953d850ac423ed03f 390 Gene3D G3DSA:3.40.50.2300 147 283 3.1E-49 T 01-11-2018 AFULGI_00025620 8a1fb587385dfae59a57deac74c41247 197 SUPERFAMILY SSF52317 2 195 1.48E-49 T 01-11-2018 IPR029062 Class I glutamine amidotransferase-like AFULGI_00025620 8a1fb587385dfae59a57deac74c41247 197 PIRSF PIRSF000495 1 197 4.8E-71 T 01-11-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 AFULGI_00025620 8a1fb587385dfae59a57deac74c41247 197 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 1 194 35.395 T 01-11-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 AFULGI_00025620 8a1fb587385dfae59a57deac74c41247 197 Gene3D G3DSA:3.40.50.880 1 197 1.3E-69 T 01-11-2018 IPR029062 Class I glutamine amidotransferase-like AFULGI_00025620 8a1fb587385dfae59a57deac74c41247 197 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 2 193 9.8E-69 T 01-11-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 AFULGI_00025620 8a1fb587385dfae59a57deac74c41247 197 Pfam PF00117 Glutamine amidotransferase class-I 4 192 1.1E-23 T 01-11-2018 IPR017926 Glutamine amidotransferase AFULGI_00013880 fb89d810fda132ddff68ea222336bd10 290 Hamap MF_00082 Acetylglutamate kinase [argB]. 19 283 49.817 T 01-11-2018 IPR037528 Acetylglutamate kinase ArgB GO:0003991|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 AFULGI_00013880 fb89d810fda132ddff68ea222336bd10 290 PIRSF PIRSF000728 5 290 5.9E-109 T 01-11-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 AFULGI_00013880 fb89d810fda132ddff68ea222336bd10 290 TIGRFAM TIGR00761 argB: acetylglutamate kinase 21 265 2.7E-90 T 01-11-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 AFULGI_00013880 fb89d810fda132ddff68ea222336bd10 290 Gene3D G3DSA:3.40.1160.10 1 290 4.2E-100 T 01-11-2018 IPR036393 Acetylglutamate kinase-like superfamily AFULGI_00013880 fb89d810fda132ddff68ea222336bd10 290 SUPERFAMILY SSF53633 2 289 3.14E-89 T 01-11-2018 IPR036393 Acetylglutamate kinase-like superfamily AFULGI_00013880 fb89d810fda132ddff68ea222336bd10 290 Pfam PF00696 Amino acid kinase family 21 267 2.9E-48 T 01-11-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 AFULGI_00007130 7050872c9d7cfdbca08ebd61db82a689 77 ProDom PD002830 NIFU NIFU NITROGEN-FIXING C-TERMINAL FIXATION NITROGEN NIFU-LIKE DOMAIN CLUSTER HESB/YADR/YFHF:NITROGEN-FIXING 14 66 8.0E-25 T 01-11-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 AFULGI_00007130 7050872c9d7cfdbca08ebd61db82a689 77 SUPERFAMILY SSF117916 2 77 1.96E-23 T 01-11-2018 IPR034904 Fe-S cluster assembly domain superfamily AFULGI_00007130 7050872c9d7cfdbca08ebd61db82a689 77 Pfam PF01106 NifU-like domain 7 75 2.1E-27 T 01-11-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 AFULGI_00007130 7050872c9d7cfdbca08ebd61db82a689 77 Gene3D G3DSA:3.30.300.130 1 77 3.0E-27 T 01-11-2018 IPR034904 Fe-S cluster assembly domain superfamily AFULGI_00016900 474cea72dfa2b8c8b88021f3a708f447 364 Gene3D G3DSA:3.60.21.10 1 242 4.6E-53 T 01-11-2018 IPR029052 Metallo-dependent phosphatase-like AFULGI_00016900 474cea72dfa2b8c8b88021f3a708f447 364 Hamap MF_02044 DNA double-strand break repair protein Mre11 [mre11]. 1 362 22.384 T 01-11-2018 IPR032885 DNA double-strand break repair protein Mre11, archaea-type GO:0006302 AFULGI_00016900 474cea72dfa2b8c8b88021f3a708f447 364 Pfam PF00149 Calcineurin-like phosphoesterase 1 188 6.2E-13 T 01-11-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 AFULGI_00016900 474cea72dfa2b8c8b88021f3a708f447 364 SUPERFAMILY SSF56300 1 281 1.29E-48 T 01-11-2018 AFULGI_00013050 46560342c5587e4bdaad4086c07fad42 315 Gene3D G3DSA:3.40.50.720 1 188 3.7E-61 T 01-11-2018 AFULGI_00013050 46560342c5587e4bdaad4086c07fad42 315 PIRSF PIRSF000105 2 313 5.4E-72 T 01-11-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 AFULGI_00013050 46560342c5587e4bdaad4086c07fad42 315 Gene3D G3DSA:1.10.1040.10 189 313 3.6E-30 T 01-11-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AFULGI_00013050 46560342c5587e4bdaad4086c07fad42 315 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 4 185 6.7E-60 T 01-11-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 AFULGI_00013050 46560342c5587e4bdaad4086c07fad42 315 SUPERFAMILY SSF51735 4 184 3.07E-50 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily AFULGI_00013050 46560342c5587e4bdaad4086c07fad42 315 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 188 274 1.9E-17 T 01-11-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 AFULGI_00013050 46560342c5587e4bdaad4086c07fad42 315 SUPERFAMILY SSF48179 188 257 9.35E-12 T 01-11-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AFULGI_00010720 e085c5eecc1beeda85236abc910258a8 292 Gene3D G3DSA:3.40.190.10 26 290 3.5E-102 T 01-11-2018 AFULGI_00010720 e085c5eecc1beeda85236abc910258a8 292 SUPERFAMILY SSF53850 24 291 1.23E-71 T 01-11-2018 AFULGI_00010720 e085c5eecc1beeda85236abc910258a8 292 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 24 287 7.4E-64 T 01-11-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0022857|GO:0043190|GO:0055085 AFULGI_00010720 e085c5eecc1beeda85236abc910258a8 292 Gene3D G3DSA:3.40.190.120 127 230 3.5E-102 T 01-11-2018 AFULGI_00019090 36fe32c422638bb0426bc4f09f16c1f8 199 TIGRFAM TIGR04088 cognate_SipW: SipW-cognate class signal peptide 8 42 2.9E-10 T 01-11-2018 IPR023833 Signal peptide, camelysin AFULGI_00019090 36fe32c422638bb0426bc4f09f16c1f8 199 Pfam PF12389 Camelysin metallo-endopeptidase 2 69 1.1E-6 T 01-11-2018 IPR022121 Peptidase M73, camelysin AFULGI_00016180 d3b05978ecffbdedfe539dd0a8a3cb16 110 Pfam PF01909 Nucleotidyltransferase domain 17 105 3.2E-13 T 01-11-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 AFULGI_00016180 d3b05978ecffbdedfe539dd0a8a3cb16 110 Gene3D G3DSA:3.30.460.10 4 108 5.7E-21 T 01-11-2018 AFULGI_00016180 d3b05978ecffbdedfe539dd0a8a3cb16 110 SUPERFAMILY SSF81301 9 109 1.52E-20 T 01-11-2018 AFULGI_00014010 e4b5b4779c329504a7f6a170da3a4622 395 Pfam PF02803 Thiolase, C-terminal domain 269 362 1.0E-10 T 01-11-2018 IPR020617 Thiolase, C-terminal GO:0016747 AFULGI_00014010 e4b5b4779c329504a7f6a170da3a4622 395 Gene3D G3DSA:3.40.47.10 3 393 8.7E-112 T 01-11-2018 IPR016039 Thiolase-like GO:0003824 AFULGI_00014010 e4b5b4779c329504a7f6a170da3a4622 395 Pfam PF00108 Thiolase, N-terminal domain 4 229 4.4E-16 T 01-11-2018 IPR020616 Thiolase, N-terminal GO:0016747 AFULGI_00014010 e4b5b4779c329504a7f6a170da3a4622 395 PIRSF PIRSF000429 1 390 1.4E-60 T 01-11-2018 IPR002155 Thiolase GO:0016747 AFULGI_00014010 e4b5b4779c329504a7f6a170da3a4622 395 SUPERFAMILY SSF53901 4 359 9.33E-40 T 01-11-2018 IPR016039 Thiolase-like GO:0003824 AFULGI_00020260 35ab31c338b9b961cec400e48a6facef 322 Gene3D G3DSA:3.20.20.140 42 281 8.4E-17 T 01-11-2018 AFULGI_00020260 35ab31c338b9b961cec400e48a6facef 322 SUPERFAMILY SSF51556 40 277 2.51E-25 T 01-11-2018 IPR032466 Metal-dependent hydrolase AFULGI_00020260 35ab31c338b9b961cec400e48a6facef 322 Pfam PF01979 Amidohydrolase family 37 262 1.6E-5 T 01-11-2018 IPR006680 Amidohydrolase-related GO:0016787 AFULGI_00000340 b8e5826b8f3a3baa6f090ae91599bb3b 80 Pfam PF14947 Winged helix-turn-helix 1 71 3.5E-23 T 01-11-2018 IPR038723 ArnR1-like, winged helix-turn-helix domain AFULGI_00000340 b8e5826b8f3a3baa6f090ae91599bb3b 80 SUPERFAMILY SSF46785 3 73 2.28E-13 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00000340 b8e5826b8f3a3baa6f090ae91599bb3b 80 Gene3D G3DSA:1.10.10.10 1 80 5.0E-21 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00024020 03401f2d52beb939f53425da33f653f1 244 ProDom PD359573 MEMBRANE TRANSMEMBRANE AF2132 PROTEIN 3 242 8.0E-103 T 01-11-2018 AFULGI_00024060 d2bab0a51a60da1b5a09ec31ebc60bef 171 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 57 72 1.4E-9 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFULGI_00024060 d2bab0a51a60da1b5a09ec31ebc60bef 171 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 10 25 1.4E-9 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFULGI_00024060 d2bab0a51a60da1b5a09ec31ebc60bef 171 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 42 57 1.4E-9 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFULGI_00024060 d2bab0a51a60da1b5a09ec31ebc60bef 171 Pfam PF01022 Bacterial regulatory protein, arsR family 15 61 2.8E-17 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFULGI_00024060 d2bab0a51a60da1b5a09ec31ebc60bef 171 Gene3D G3DSA:1.10.10.10 6 84 2.3E-20 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00024060 d2bab0a51a60da1b5a09ec31ebc60bef 171 SUPERFAMILY SSF46785 8 81 3.97E-24 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00024060 d2bab0a51a60da1b5a09ec31ebc60bef 171 SMART SM00418 8 88 3.7E-23 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFULGI_00024960 d377acf9a60ebce394e982107acc62fe 88 Gene3D G3DSA:3.50.50.60 1 88 8.6E-17 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFULGI_00024960 d377acf9a60ebce394e982107acc62fe 88 SUPERFAMILY SSF51905 1 86 4.1E-11 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFULGI_00022860 9e0d5c2511e3b668b25107138b59123a 332 Gene3D G3DSA:3.30.420.40 140 289 7.6E-31 T 01-11-2018 AFULGI_00022860 9e0d5c2511e3b668b25107138b59123a 332 Gene3D G3DSA:3.30.420.40 4 290 7.6E-31 T 01-11-2018 AFULGI_00022860 9e0d5c2511e3b668b25107138b59123a 332 Gene3D G3DSA:3.90.640.10 171 230 7.6E-31 T 01-11-2018 AFULGI_00022860 9e0d5c2511e3b668b25107138b59123a 332 Pfam PF06723 MreB/Mbl protein 4 297 1.2E-15 T 01-11-2018 IPR004753 Cell shape determining protein MreB GO:0000902 AFULGI_00022860 9e0d5c2511e3b668b25107138b59123a 332 SUPERFAMILY SSF53067 1 140 1.41E-24 T 01-11-2018 AFULGI_00022860 9e0d5c2511e3b668b25107138b59123a 332 SUPERFAMILY SSF53067 141 301 1.01E-19 T 01-11-2018 AFULGI_00014650 0607e97481242135ce08a9e072a59944 305 Pfam PF13462 Thioredoxin 130 299 1.4E-34 T 01-11-2018 IPR012336 Thioredoxin-like fold AFULGI_00014650 0607e97481242135ce08a9e072a59944 305 Gene3D G3DSA:3.40.30.10 114 304 8.2E-57 T 01-11-2018 AFULGI_00014650 0607e97481242135ce08a9e072a59944 305 SUPERFAMILY SSF52833 127 301 1.11E-44 T 01-11-2018 IPR036249 Thioredoxin-like superfamily AFULGI_00011030 cada760193d47a9b4c8f7a1817c6470e 285 Pfam PF13175 AAA ATPase domain 1 193 1.5E-18 T 01-11-2018 AFULGI_00011030 cada760193d47a9b4c8f7a1817c6470e 285 Gene3D G3DSA:3.40.50.300 1 271 1.6E-14 T 01-11-2018 AFULGI_00011030 cada760193d47a9b4c8f7a1817c6470e 285 SUPERFAMILY SSF52540 1 131 3.49E-13 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00013780 85066415278f9bd89aee8b67d36a89d8 92 Pfam PF01022 Bacterial regulatory protein, arsR family 15 58 7.6E-10 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFULGI_00013780 85066415278f9bd89aee8b67d36a89d8 92 SMART SM00418 5 84 1.2E-21 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFULGI_00013780 85066415278f9bd89aee8b67d36a89d8 92 SUPERFAMILY SSF46785 2 89 9.26E-19 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00013780 85066415278f9bd89aee8b67d36a89d8 92 Gene3D G3DSA:1.10.10.10 4 91 3.9E-17 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00008620 8ef9479829189b71d20bf03ff8eba1c6 122 Pfam PF04472 Cell division protein SepF 39 112 2.0E-14 T 01-11-2018 IPR007561 Cell division protein SepF/SepF-related GO:0090529 AFULGI_00008620 8ef9479829189b71d20bf03ff8eba1c6 122 Gene3D G3DSA:3.30.110.150 37 122 4.2E-29 T 01-11-2018 IPR038594 SepF-like superfamily AFULGI_00008620 8ef9479829189b71d20bf03ff8eba1c6 122 PIRSF PIRSF019313 1 122 8.1E-51 T 01-11-2018 IPR012426 Uncharacterised protein family SepF-related, archaea AFULGI_00010420 9d19a171acf6da474670f14d148b8a32 378 SUPERFAMILY SSF56235 16 365 4.46E-91 T 01-11-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFULGI_00010420 9d19a171acf6da474670f14d148b8a32 378 Pfam PF00310 Glutamine amidotransferases class-II 78 226 1.2E-13 T 01-11-2018 IPR017932 Glutamine amidotransferase type 2 domain AFULGI_00010420 9d19a171acf6da474670f14d148b8a32 378 PIRSF PIRSF018774 1 378 6.5E-204 T 01-11-2018 IPR012375 Glutamate synthase large subunit domain 1 stand-alone protein AFULGI_00010420 9d19a171acf6da474670f14d148b8a32 378 Gene3D G3DSA:3.60.20.10 51 377 3.2E-56 T 01-11-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFULGI_00008190 0c1056a8cb76ce8dab6fe054e145bcf6 93 SUPERFAMILY SSF140371 1 70 7.32E-24 T 01-11-2018 IPR036519 Uncharacterised UPF0058 superfamily AFULGI_00008190 0c1056a8cb76ce8dab6fe054e145bcf6 93 Pfam PF01893 Uncharacterised protein family UPF0058 1 71 5.2E-26 T 01-11-2018 IPR002753 Uncharacterised protein family UPF0058 AFULGI_00008190 0c1056a8cb76ce8dab6fe054e145bcf6 93 Gene3D G3DSA:1.20.1270.110 1 72 4.7E-23 T 01-11-2018 IPR036519 Uncharacterised UPF0058 superfamily AFULGI_00008780 0527c354ccdf8cd8f0b48c2b9d785fbc 201 TIGRFAM TIGR03879 near_KaiC_dom: probable regulatory domain 27 120 1.6E-37 T 01-11-2018 IPR022285 Conserved hypothetical protein CHP03879, regulatory domain, putative AFULGI_00022380 cc6c96ab9351988de7a44369941a6e9d 102 Pfam PF03091 CutA1 divalent ion tolerance protein 4 99 3.6E-37 T 01-11-2018 IPR004323 Divalent ion tolerance protein, CutA GO:0010038 AFULGI_00022380 cc6c96ab9351988de7a44369941a6e9d 102 SUPERFAMILY SSF54913 4 101 2.34E-36 T 01-11-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta AFULGI_00022380 cc6c96ab9351988de7a44369941a6e9d 102 Gene3D G3DSA:3.30.70.120 1 102 3.0E-42 T 01-11-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal AFULGI_00001400 8a14db818e6505b50d6111424c1f86b1 623 Gene3D G3DSA:2.60.40.420 25 141 2.0E-18 T 01-11-2018 IPR008972 Cupredoxin AFULGI_00001400 8a14db818e6505b50d6111424c1f86b1 623 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 81 134 - T 01-11-2018 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFULGI_00001400 8a14db818e6505b50d6111424c1f86b1 623 SUPERFAMILY SSF49503 34 142 2.44E-15 T 01-11-2018 IPR008972 Cupredoxin AFULGI_00015740 c405edef720eed7917d048c3c757a189 875 SUPERFAMILY SSF52540 36 400 7.4E-42 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00015740 c405edef720eed7917d048c3c757a189 875 Gene3D G3DSA:3.40.50.300 6 209 1.3E-18 T 01-11-2018 AFULGI_00015740 c405edef720eed7917d048c3c757a189 875 Gene3D G3DSA:3.40.50.300 226 402 6.6E-21 T 01-11-2018 AFULGI_00015740 c405edef720eed7917d048c3c757a189 875 Pfam PF10412 Type IV secretion-system coupling protein DNA-binding domain 54 393 5.7E-10 T 01-11-2018 IPR019476 Type IV secretion system coupling protein TraD, DNA-binding domain AFULGI_00026970 11a256164863313b6a6e1d447cbb93e2 147 SUPERFAMILY SSF81301 6 116 7.27E-15 T 01-11-2018 AFULGI_00026970 11a256164863313b6a6e1d447cbb93e2 147 Gene3D G3DSA:3.30.460.10 1 102 6.6E-13 T 01-11-2018 AFULGI_00026970 11a256164863313b6a6e1d447cbb93e2 147 Pfam PF01909 Nucleotidyltransferase domain 9 89 1.5E-12 T 01-11-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 AFULGI_00022780 ef56fa20783b1b512cd494c69e246070 436 PIRSF PIRSF006444 1 435 1.9E-211 T 01-11-2018 IPR011880 Phenylacetate-CoA ligase GO:0010124|GO:0047475 KEGG: 00360+6.2.1.30|MetaCyc: PWY-1341|MetaCyc: PWY-6318|MetaCyc: PWY-7716 AFULGI_00022780 ef56fa20783b1b512cd494c69e246070 436 Gene3D G3DSA:3.30.300.30 329 435 8.5E-36 T 01-11-2018 AFULGI_00022780 ef56fa20783b1b512cd494c69e246070 436 SUPERFAMILY SSF56801 29 402 1.24E-67 T 01-11-2018 AFULGI_00022780 ef56fa20783b1b512cd494c69e246070 436 Pfam PF14535 AMP-binding enzyme C-terminal domain 337 433 2.6E-32 T 01-11-2018 IPR028154 AMP-dependent ligase, C-terminal AFULGI_00022780 ef56fa20783b1b512cd494c69e246070 436 Gene3D G3DSA:3.40.50.12780 2 328 1.4E-129 T 01-11-2018 AFULGI_00022780 ef56fa20783b1b512cd494c69e246070 436 Pfam PF00501 AMP-binding enzyme 82 336 1.2E-19 T 01-11-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFULGI_00009790 4499cab3be4c6b605ff276cb059f0173 379 Gene3D G3DSA:3.40.50.2300 47 300 1.6E-144 T 01-11-2018 AFULGI_00009790 4499cab3be4c6b605ff276cb059f0173 379 Gene3D G3DSA:3.40.50.2300 147 366 1.6E-144 T 01-11-2018 AFULGI_00009790 4499cab3be4c6b605ff276cb059f0173 379 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 45 344 2.7E-97 T 01-11-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 AFULGI_00011550 bb4e743d3047ea188d7da68fd0bd7f93 118 Gene3D G3DSA:1.20.1500.10 2 115 7.1E-20 T 01-11-2018 IPR023378 YheA/YmcA-like domain superfamily AFULGI_00011550 bb4e743d3047ea188d7da68fd0bd7f93 118 Pfam PF06133 Control of competence regulator ComK, YlbF/YmcA 6 109 3.7E-20 T 01-11-2018 IPR010368 Control of competence regulator ComK, YlbF/YmcA AFULGI_00011550 bb4e743d3047ea188d7da68fd0bd7f93 118 SUPERFAMILY SSF158622 6 109 1.83E-21 T 01-11-2018 IPR023378 YheA/YmcA-like domain superfamily AFULGI_00024390 38395be81a05abddeb384dcd635f8828 124 SUPERFAMILY SSF81301 16 90 1.09E-8 T 01-11-2018 AFULGI_00016640 9443dd673f24612cd2c43f2dc9263851 160 SUPERFAMILY SSF74853 38 160 6.02E-25 T 01-11-2018 IPR036415 Lamin tail domain superfamily AFULGI_00016640 9443dd673f24612cd2c43f2dc9263851 160 Pfam PF00932 Lamin Tail Domain 55 160 3.0E-25 T 01-11-2018 IPR001322 Lamin tail domain AFULGI_00016640 9443dd673f24612cd2c43f2dc9263851 160 Gene3D G3DSA:2.60.40.1260 32 159 1.5E-10 T 01-11-2018 IPR036415 Lamin tail domain superfamily AFULGI_00017770 2a3f762315fcec1e767f0018b9b5acd4 103 Pfam PF04266 ASCH domain 5 103 1.9E-16 T 01-11-2018 IPR007374 ASCH domain AFULGI_00017770 2a3f762315fcec1e767f0018b9b5acd4 103 SUPERFAMILY SSF88697 3 102 3.73E-18 T 01-11-2018 IPR015947 PUA-like superfamily AFULGI_00017770 2a3f762315fcec1e767f0018b9b5acd4 103 SMART SM01022 4 103 1.5E-21 T 01-11-2018 IPR007374 ASCH domain AFULGI_00001260 8f7af9fb681d89f00a2a2a688f755c03 218 Pfam PF04493 Endonuclease V 12 202 8.3E-58 T 01-11-2018 IPR007581 Endonuclease V GO:0004519|GO:0006281 AFULGI_00001260 8f7af9fb681d89f00a2a2a688f755c03 218 Gene3D G3DSA:3.30.2170.10 1 216 1.4E-64 T 01-11-2018 AFULGI_00001260 8f7af9fb681d89f00a2a2a688f755c03 218 Hamap MF_00801 Endonuclease V [nfi]. 2 211 33.093 T 01-11-2018 IPR007581 Endonuclease V GO:0004519|GO:0006281 AFULGI_00003600 4ef414b30a0270d7626901cc2536fe8d 79 SUPERFAMILY SSF50346 2 74 2.62E-12 T 01-11-2018 IPR011033 PRC-barrel-like superfamily AFULGI_00003600 4ef414b30a0270d7626901cc2536fe8d 79 Gene3D G3DSA:2.30.30.240 5 77 7.5E-8 T 01-11-2018 AFULGI_00003600 4ef414b30a0270d7626901cc2536fe8d 79 Pfam PF05239 PRC-barrel domain 5 76 4.3E-11 T 01-11-2018 IPR027275 PRC-barrel domain AFULGI_00008840 320b2f427d93a83f5ac89515f18a8ac6 152 Gene3D G3DSA:1.10.287.10 82 150 2.6E-26 T 01-11-2018 AFULGI_00008840 320b2f427d93a83f5ac89515f18a8ac6 152 Pfam PF08069 Ribosomal S13/S15 N-terminal domain 1 60 2.0E-27 T 01-11-2018 IPR012606 Ribosomal protein S13/S15, N-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00008840 320b2f427d93a83f5ac89515f18a8ac6 152 SMART SM01386 1 60 3.4E-33 T 01-11-2018 IPR012606 Ribosomal protein S13/S15, N-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00008840 320b2f427d93a83f5ac89515f18a8ac6 152 SUPERFAMILY SSF47060 66 146 9.12E-21 T 01-11-2018 IPR009068 S15/NS1, RNA-binding AFULGI_00008840 320b2f427d93a83f5ac89515f18a8ac6 152 Gene3D G3DSA:1.10.8.1030 35 81 3.3E-19 T 01-11-2018 AFULGI_00008840 320b2f427d93a83f5ac89515f18a8ac6 152 Hamap MF_01343_A 30S ribosomal protein S15 [rpsO]. 3 149 35.702 T 01-11-2018 IPR023029 Ribosomal protein S15P Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00008840 320b2f427d93a83f5ac89515f18a8ac6 152 Pfam PF00312 Ribosomal protein S15 73 148 3.1E-15 T 01-11-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFULGI_00008840 320b2f427d93a83f5ac89515f18a8ac6 152 ProSitePatterns PS00362 Ribosomal protein S15 signature. 98 128 - T 01-11-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFULGI_00008840 320b2f427d93a83f5ac89515f18a8ac6 152 SMART SM01387 70 149 5.6E-17 T 01-11-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFULGI_00025780 65d506ffaeef37c98e9f73bb460a2166 100 TIGRFAM TIGR00304 TIGR00304: TIGR00304 family protein 4 95 3.7E-38 T 01-11-2018 IPR002849 Protein of unknown function DUF131 AFULGI_00025780 65d506ffaeef37c98e9f73bb460a2166 100 Pfam PF01998 Protein of unknown function DUF131 39 96 9.3E-18 T 01-11-2018 IPR002849 Protein of unknown function DUF131 AFULGI_00007380 0166ef5dabb16ea08f2e68c32b8ee21b 614 Gene3D G3DSA:1.20.81.30 406 522 2.1E-14 T 01-11-2018 AFULGI_00007380 0166ef5dabb16ea08f2e68c32b8ee21b 614 Pfam PF00482 Type II secretion system (T2SS), protein F 130 258 2.5E-18 T 01-11-2018 IPR018076 Type II secretion system F domain AFULGI_00007380 0166ef5dabb16ea08f2e68c32b8ee21b 614 Pfam PF00482 Type II secretion system (T2SS), protein F 414 539 1.9E-19 T 01-11-2018 IPR018076 Type II secretion system F domain AFULGI_00014120 3908b3684b61ef6b9ba4c7b42c6c6396 303 Pfam PF00005 ABC transporter 24 164 1.6E-24 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFULGI_00014120 3908b3684b61ef6b9ba4c7b42c6c6396 303 SUPERFAMILY SSF52540 4 229 6.82E-56 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00014120 3908b3684b61ef6b9ba4c7b42c6c6396 303 SMART SM00382 33 212 1.8E-11 T 01-11-2018 IPR003593 AAA+ ATPase domain AFULGI_00014120 3908b3684b61ef6b9ba4c7b42c6c6396 303 Gene3D G3DSA:3.40.50.300 1 241 9.2E-58 T 01-11-2018 AFULGI_00026140 8b0b353479949a7202f7bfaa81825674 147 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 64 146 9.2E-25 T 01-11-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 AFULGI_00026140 8b0b353479949a7202f7bfaa81825674 147 SUPERFAMILY SSF46767 62 146 7.85E-23 T 01-11-2018 IPR036217 Methylated DNA-protein cysteine methyltransferase, DNA binding domain Reactome: R-HSA-5657655 AFULGI_00026140 8b0b353479949a7202f7bfaa81825674 147 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 63 144 2.7E-24 T 01-11-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 AFULGI_00026140 8b0b353479949a7202f7bfaa81825674 147 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 110 116 - T 01-11-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 AFULGI_00026140 8b0b353479949a7202f7bfaa81825674 147 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 2 145 36.905 T 01-11-2018 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 AFULGI_00026140 8b0b353479949a7202f7bfaa81825674 147 Gene3D G3DSA:1.10.10.10 60 147 2.2E-29 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00002970 77470e7a3a36749f354844ca340d3e86 67 Pfam PF10047 Protein of unknown function (DUF2281) 5 61 2.2E-19 T 01-11-2018 IPR018739 Domain of unknown function DUF2281 AFULGI_00021150 45c15a58d737183c2cba07cfa0295014 57 Gene3D G3DSA:1.20.120.580 1 56 4.4E-5 T 01-11-2018 IPR037038 Bsu32300-like superfamily AFULGI_00011430 e427c0a7f9b45d955d1ecb1036f2863a 223 SMART SM00388 153 209 0.0051 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFULGI_00011430 e427c0a7f9b45d955d1ecb1036f2863a 223 Gene3D G3DSA:1.10.287.130 107 207 4.8E-5 T 01-11-2018 AFULGI_00019230 df223f7a131167b7e26bdd927a055a6a 351 Gene3D G3DSA:3.40.50.1970 1 155 3.4E-33 T 01-11-2018 AFULGI_00019230 df223f7a131167b7e26bdd927a055a6a 351 Pfam PF13685 Iron-containing alcohol dehydrogenase 13 268 3.4E-72 T 01-11-2018 IPR032837 Glycerol-1-phosphate dehydrogenase KEGG: 00564+1.1.1.261|MetaCyc: PWY-6349 AFULGI_00019230 df223f7a131167b7e26bdd927a055a6a 351 Gene3D G3DSA:1.20.1090.10 156 350 2.8E-51 T 01-11-2018 AFULGI_00019230 df223f7a131167b7e26bdd927a055a6a 351 SUPERFAMILY SSF56796 3 336 2.88E-63 T 01-11-2018 AFULGI_00019230 df223f7a131167b7e26bdd927a055a6a 351 Hamap MF_00497_A Glycerol-1-phosphate dehydrogenase [NAD(P)+] [egsA]. 5 351 40.027 T 01-11-2018 IPR023002 Glycerol-1-phosphate dehydrogenase, archaea GO:0050492|GO:0055114 KEGG: 00564+1.1.1.261|MetaCyc: PWY-6349 AFULGI_00019230 df223f7a131167b7e26bdd927a055a6a 351 PIRSF PIRSF000112 2 347 1.7E-61 T 01-11-2018 IPR016205 Glycerol dehydrogenase GO:0016614|GO:0046872|GO:0055114 KEGG: 00564+1.1.1.261|MetaCyc: PWY-6349 AFULGI_00014170 ca6223d0ee7ba6e230bd14910637f691 275 Pfam PF04015 Domain of unknown function (DUF362) 32 219 1.1E-34 T 01-11-2018 IPR007160 Domain of unknown function DUF362 AFULGI_00007740 2086dc182c8ba7da008d9e1c0916cfee 643 Pfam PF00136 DNA polymerase family B 308 346 2.9E-9 T 01-11-2018 IPR006134 DNA-directed DNA polymerase, family B, multifunctional domain GO:0000166|GO:0003677 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFULGI_00007740 2086dc182c8ba7da008d9e1c0916cfee 643 SUPERFAMILY SSF53098 3 236 4.44E-12 T 01-11-2018 IPR012337 Ribonuclease H-like superfamily AFULGI_00007740 2086dc182c8ba7da008d9e1c0916cfee 643 Gene3D G3DSA:1.10.132.60 500 642 2.9E-9 T 01-11-2018 AFULGI_00007740 2086dc182c8ba7da008d9e1c0916cfee 643 SMART SM00486 22 448 0.0017 T 01-11-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFULGI_00007740 2086dc182c8ba7da008d9e1c0916cfee 643 Gene3D G3DSA:3.90.1600.10 312 474 1.9E-40 T 01-11-2018 IPR023211 DNA polymerase, palm domain superfamily KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFULGI_00007740 2086dc182c8ba7da008d9e1c0916cfee 643 Gene3D G3DSA:1.10.287.690 351 403 1.9E-40 T 01-11-2018 AFULGI_00007740 2086dc182c8ba7da008d9e1c0916cfee 643 SUPERFAMILY SSF56672 271 638 1.78E-69 T 01-11-2018 AFULGI_00015570 b2ab6b9ca5723f6c5826e1ab4b0409f7 245 SUPERFAMILY SSF52540 2 239 6.81E-39 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00015570 b2ab6b9ca5723f6c5826e1ab4b0409f7 245 Pfam PF06745 KaiC 5 241 1.1E-78 T 01-11-2018 IPR014774 KaiC-like domain AFULGI_00015570 b2ab6b9ca5723f6c5826e1ab4b0409f7 245 Gene3D G3DSA:3.40.50.300 1 244 1.1E-62 T 01-11-2018 AFULGI_00006230 bde0eba0b52291495da562d06a5a5e06 91 Hamap MF_01471 CRISPR-associated endoribonuclease Cas2 [cas2]. 1 89 16.715 T 01-11-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 AFULGI_00006230 bde0eba0b52291495da562d06a5a5e06 91 Gene3D G3DSA:3.30.70.240 1 66 6.6E-22 T 01-11-2018 AFULGI_00006230 bde0eba0b52291495da562d06a5a5e06 91 TIGRFAM TIGR01573 cas2: CRISPR-associated endonuclease Cas2 1 88 2.3E-17 T 01-11-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 AFULGI_00006230 bde0eba0b52291495da562d06a5a5e06 91 Pfam PF09827 CRISPR associated protein Cas2 1 71 6.4E-18 T 01-11-2018 IPR019199 Virulence-associated protein D / CRISPR associated protein Cas2 AFULGI_00006230 bde0eba0b52291495da562d06a5a5e06 91 SUPERFAMILY SSF143430 1 78 5.76E-18 T 01-11-2018 AFULGI_00012800 b5f8efc1b27d33c11f723e106f04e459 434 SUPERFAMILY SSF56024 283 404 3.14E-18 T 01-11-2018 AFULGI_00012800 b5f8efc1b27d33c11f723e106f04e459 434 Pfam PF13091 PLD-like domain 287 404 6.6E-17 T 01-11-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 AFULGI_00012800 b5f8efc1b27d33c11f723e106f04e459 434 Gene3D G3DSA:3.30.870.10 281 405 1.9E-21 T 01-11-2018 AFULGI_00025090 a18d2f3413289144657d81a7b076e9e0 404 Gene3D G3DSA:3.20.20.70 19 262 1.7E-23 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFULGI_00025090 a18d2f3413289144657d81a7b076e9e0 404 SUPERFAMILY SSF102114 20 234 3.01E-24 T 01-11-2018 AFULGI_00020850 096bcbef9438018300057e76ea32bdc8 366 Pfam PF00146 NADH dehydrogenase 58 357 3.8E-81 T 01-11-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFULGI_00020850 096bcbef9438018300057e76ea32bdc8 366 Hamap MF_01350 NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic [ndhA]. 42 365 18.255 T 01-11-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFULGI_00023760 162cb7bb6d0fce6dc6026f7726d6f2ca 280 Pfam PF02593 Domain of unknown function 9 264 8.7E-80 T 01-11-2018 IPR003745 Protein of unknown function DUF166 AFULGI_00026360 146b863c8ce700a972aab82d70088935 247 SUPERFAMILY SSF53474 20 245 4.29E-46 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold AFULGI_00026360 146b863c8ce700a972aab82d70088935 247 Gene3D G3DSA:3.40.50.1820 2 247 3.9E-67 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold AFULGI_00026360 146b863c8ce700a972aab82d70088935 247 PRINTS PR00111 Alpha/beta hydrolase fold signature 98 111 2.2E-8 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 AFULGI_00026360 146b863c8ce700a972aab82d70088935 247 PRINTS PR00111 Alpha/beta hydrolase fold signature 84 97 2.2E-8 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 AFULGI_00026360 146b863c8ce700a972aab82d70088935 247 PRINTS PR00111 Alpha/beta hydrolase fold signature 190 204 2.2E-8 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 AFULGI_00026360 146b863c8ce700a972aab82d70088935 247 Pfam PF12697 Alpha/beta hydrolase family 26 239 1.8E-21 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 AFULGI_00006830 c61ccdbf73d86edf5630053cd2b506a3 363 Gene3D G3DSA:3.40.50.2000 169 337 6.4E-33 T 01-11-2018 AFULGI_00006830 c61ccdbf73d86edf5630053cd2b506a3 363 SUPERFAMILY SSF53756 3 347 3.92E-47 T 01-11-2018 AFULGI_00006830 c61ccdbf73d86edf5630053cd2b506a3 363 Pfam PF00534 Glycosyl transferases group 1 181 337 3.4E-28 T 01-11-2018 IPR001296 Glycosyl transferase, family 1 AFULGI_00015530 318d066fbcf583342b9e97a116bf8108 371 Pfam PF00733 Asparagine synthase 268 364 4.6E-14 T 01-11-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 AFULGI_00015530 318d066fbcf583342b9e97a116bf8108 371 Pfam PF00733 Asparagine synthase 155 265 3.3E-13 T 01-11-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 AFULGI_00015530 318d066fbcf583342b9e97a116bf8108 371 Gene3D G3DSA:3.40.50.620 131 370 6.2E-50 T 01-11-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFULGI_00015530 318d066fbcf583342b9e97a116bf8108 371 SUPERFAMILY SSF52402 133 368 1.33E-35 T 01-11-2018 AFULGI_00004350 7f0a69d9ee477053bdf3e73ca7fa15b9 334 SUPERFAMILY SSF81345 4 331 1.31E-83 T 01-11-2018 IPR037294 ABC transporter, BtuC-like AFULGI_00004350 7f0a69d9ee477053bdf3e73ca7fa15b9 334 Pfam PF01032 FecCD transport family 18 331 9.5E-96 T 01-11-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 AFULGI_00004350 7f0a69d9ee477053bdf3e73ca7fa15b9 334 Gene3D G3DSA:1.10.3470.10 1 333 4.8E-101 T 01-11-2018 IPR037294 ABC transporter, BtuC-like AFULGI_00020670 db8a0fde374c30f277282c8d8196794a 115 Pfam PF06935 Protein of unknown function (DUF1284) 18 113 1.0E-20 T 01-11-2018 IPR009702 Protein of unknown function DUF1284 AFULGI_00021310 5db33cf6e4d8254697ba2185aea40a80 316 TIGRFAM TIGR02583 DevR_archaea: CRISPR-associated protein Cas7/Csa2, subtype I-A/APERN 5 285 1.1E-111 T 01-11-2018 IPR002764 CRISPR-associated protein Cas7/Cst2/DevR, subtype I-a/Apern AFULGI_00021310 5db33cf6e4d8254697ba2185aea40a80 316 Pfam PF01905 CRISPR-associated negative auto-regulator DevR/Csa2 8 277 3.2E-86 T 01-11-2018 IPR010154 CRISPR-associated protein Cas7/Cst2/DevR AFULGI_00021310 5db33cf6e4d8254697ba2185aea40a80 316 TIGRFAM TIGR01875 cas_MJ0381: CRISPR-associated autoregulator DevR family 6 263 2.1E-62 T 01-11-2018 IPR010154 CRISPR-associated protein Cas7/Cst2/DevR AFULGI_00006660 bee5b09f9bb0d97b94bdc548c5db8eb7 135 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 14 132 10.499 T 01-11-2018 IPR022907 VapC family GO:0004540 AFULGI_00006660 bee5b09f9bb0d97b94bdc548c5db8eb7 135 SUPERFAMILY SSF88723 13 130 2.72E-30 T 01-11-2018 IPR029060 PIN-like domain superfamily AFULGI_00006660 bee5b09f9bb0d97b94bdc548c5db8eb7 135 SMART SM00670 12 111 7.7E-13 T 01-11-2018 IPR002716 PIN domain AFULGI_00006660 bee5b09f9bb0d97b94bdc548c5db8eb7 135 Gene3D G3DSA:3.40.50.1010 10 135 1.5E-36 T 01-11-2018 AFULGI_00002330 2b3bd35c7f9b89e111e6a7bae95840a5 455 Gene3D G3DSA:3.40.720.10 2 455 6.4E-33 T 01-11-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 AFULGI_00002330 2b3bd35c7f9b89e111e6a7bae95840a5 455 SUPERFAMILY SSF53649 4 453 2.62E-50 T 01-11-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 AFULGI_00002330 2b3bd35c7f9b89e111e6a7bae95840a5 455 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 5 414 4.1E-53 T 01-11-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 AFULGI_00000170 420e9c3c1f1111c58f043d2a2c2ddaab 160 SUPERFAMILY SSF50249 29 145 7.2E-28 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold AFULGI_00000170 420e9c3c1f1111c58f043d2a2c2ddaab 160 Gene3D G3DSA:1.10.12.20 26 76 4.7E-11 T 01-11-2018 AFULGI_00000170 420e9c3c1f1111c58f043d2a2c2ddaab 160 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 39 72 1.5E-12 T 01-11-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal AFULGI_00000170 420e9c3c1f1111c58f043d2a2c2ddaab 160 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 73 138 6.7E-7 T 01-11-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal AFULGI_00015520 7984e4e95882102351a6e876c4fde850 125 Pfam PF03692 Putative zinc- or iron-chelating domain 9 94 5.8E-20 T 01-11-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein AFULGI_00004630 a329634dd38edb5bd4f966be6363cbff 199 SUPERFAMILY SSF55718 95 187 3.3E-6 T 01-11-2018 IPR036527 SCP2 sterol-binding domain superfamily AFULGI_00004630 a329634dd38edb5bd4f966be6363cbff 199 Gene3D G3DSA:3.30.1050.10 93 199 1.0E-8 T 01-11-2018 IPR036527 SCP2 sterol-binding domain superfamily AFULGI_00004630 a329634dd38edb5bd4f966be6363cbff 199 Pfam PF02036 SCP-2 sterol transfer family 99 198 1.4E-12 T 01-11-2018 IPR003033 SCP2 sterol-binding domain AFULGI_00024810 1f5d57d174940c42f4d6ee01d2db8cf6 254 Pfam PF03029 Conserved hypothetical ATP binding protein 9 243 5.1E-67 T 01-11-2018 IPR004130 GPN-loop GTPase AFULGI_00024810 1f5d57d174940c42f4d6ee01d2db8cf6 254 Gene3D G3DSA:3.40.50.300 1 245 8.1E-60 T 01-11-2018 AFULGI_00024810 1f5d57d174940c42f4d6ee01d2db8cf6 254 SUPERFAMILY SSF52540 6 241 7.2E-39 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00012730 60530cd606bae2840a1d096c4c625a88 206 SUPERFAMILY SSF55718 1 206 2.83E-29 T 01-11-2018 IPR036527 SCP2 sterol-binding domain superfamily AFULGI_00012730 60530cd606bae2840a1d096c4c625a88 206 Pfam PF02036 SCP-2 sterol transfer family 93 192 3.3E-16 T 01-11-2018 IPR003033 SCP2 sterol-binding domain AFULGI_00012730 60530cd606bae2840a1d096c4c625a88 206 Gene3D G3DSA:3.30.1050.10 78 202 5.4E-19 T 01-11-2018 IPR036527 SCP2 sterol-binding domain superfamily AFULGI_00012730 60530cd606bae2840a1d096c4c625a88 206 Gene3D G3DSA:3.30.1050.10 4 58 1.9E-6 T 01-11-2018 IPR036527 SCP2 sterol-binding domain superfamily AFULGI_00007640 8e42d67f6637268ca996ef31acabdb0d 114 Gene3D G3DSA:1.20.1300.10 5 114 5.7E-19 T 01-11-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFULGI_00007640 8e42d67f6637268ca996ef31acabdb0d 114 PIRSF PIRSF000178 11 114 4.6E-7 T 01-11-2018 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFULGI_00007640 8e42d67f6637268ca996ef31acabdb0d 114 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 11 104 2.6E-16 T 01-11-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFULGI_00007640 8e42d67f6637268ca996ef31acabdb0d 114 SUPERFAMILY SSF81343 8 113 5.67E-22 T 01-11-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFULGI_00012710 554642ecbba81d86a7f8835f6f958f1c 236 Pfam PF06745 KaiC 9 229 1.2E-6 T 01-11-2018 IPR014774 KaiC-like domain AFULGI_00012710 554642ecbba81d86a7f8835f6f958f1c 236 Gene3D G3DSA:3.40.50.300 9 232 3.3E-22 T 01-11-2018 AFULGI_00012710 554642ecbba81d86a7f8835f6f958f1c 236 SUPERFAMILY SSF52540 9 229 1.88E-11 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00023830 a92639560841a7bf6ef6b5be98319665 320 Pfam PF13641 Glycosyltransferase like family 2 3 224 3.2E-17 T 01-11-2018 AFULGI_00023830 a92639560841a7bf6ef6b5be98319665 320 SUPERFAMILY SSF53448 4 275 3.28E-34 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFULGI_00023830 a92639560841a7bf6ef6b5be98319665 320 Gene3D G3DSA:3.90.550.10 2 205 2.3E-27 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFULGI_00011350 deadd737c22589e4bb19d91cfa127c94 202 Pfam PF04509 CheC-like family 106 141 6.1E-12 T 01-11-2018 IPR007597 CheC-like protein GO:0016787 AFULGI_00011350 deadd737c22589e4bb19d91cfa127c94 202 Pfam PF04509 CheC-like family 10 46 7.9E-15 T 01-11-2018 IPR007597 CheC-like protein GO:0016787 AFULGI_00011350 deadd737c22589e4bb19d91cfa127c94 202 SUPERFAMILY SSF103039 7 199 8.5E-45 T 01-11-2018 IPR028976 CheC-like superfamily AFULGI_00011350 deadd737c22589e4bb19d91cfa127c94 202 Gene3D G3DSA:3.40.1550.10 6 198 2.0E-48 T 01-11-2018 IPR028976 CheC-like superfamily AFULGI_00013440 5e4dc16c96a156da9f73b9795c3cc79c 104 SUPERFAMILY SSF81324 6 73 2.62E-18 T 01-11-2018 AFULGI_00013440 5e4dc16c96a156da9f73b9795c3cc79c 104 Pfam PF07885 Ion channel 30 73 5.4E-12 T 01-11-2018 IPR013099 Potassium channel domain AFULGI_00013440 5e4dc16c96a156da9f73b9795c3cc79c 104 Gene3D G3DSA:1.10.287.70 1 81 1.9E-16 T 01-11-2018 AFULGI_00021700 b30b006004c12b82d851a38f257094e6 51 Pfam PF00253 Ribosomal protein S14p/S29e 3 50 5.9E-14 T 01-11-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFULGI_00021700 b30b006004c12b82d851a38f257094e6 51 SUPERFAMILY SSF57716 4 49 2.92E-7 T 01-11-2018 AFULGI_00021700 b30b006004c12b82d851a38f257094e6 51 Hamap MF_01364_A 30S ribosomal protein S14 type Z [rpsZ]. 1 50 18.152 T 01-11-2018 IPR023676 Ribosomal protein S14, type Z, archaeal GO:0003723|GO:0003735|GO:0006412|GO:0015935 AFULGI_00021700 b30b006004c12b82d851a38f257094e6 51 ProSitePatterns PS00527 Ribosomal protein S14 signature. 17 39 - T 01-11-2018 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00021700 b30b006004c12b82d851a38f257094e6 51 Gene3D G3DSA:4.10.830.10 1 51 3.0E-22 T 01-11-2018 AFULGI_00020590 8867545d250932b69a2524371bd78239 99 Gene3D G3DSA:1.10.10.10 23 98 2.4E-14 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00020590 8867545d250932b69a2524371bd78239 99 SUPERFAMILY SSF46785 28 96 1.95E-14 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00020590 8867545d250932b69a2524371bd78239 99 Pfam PF01022 Bacterial regulatory protein, arsR family 25 69 1.4E-14 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFULGI_00020590 8867545d250932b69a2524371bd78239 99 SMART SM00418 16 92 0.0024 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFULGI_00018220 3d9195939cc8cc72f22324f4099ae531 308 TIGRFAM TIGR04449 halocin_C8_dom: halocin C8-like bacteriocin domain 241 308 2.5E-16 T 01-11-2018 IPR031033 Halocin C8-like bacteriocin domain AFULGI_00008340 ce5c8a7f8bd7c8f7d0e6272ecac7ca44 488 PIRSF PIRSF030218 1 478 8.6E-152 T 01-11-2018 IPR016950 Mannosyltransferase, MA4085, predicted AFULGI_00008340 ce5c8a7f8bd7c8f7d0e6272ecac7ca44 488 TIGRFAM TIGR03663 TIGR03663: TIGR03663 family protein 6 411 4.1E-132 T 01-11-2018 IPR019962 Conserved hypothetical protein CHP03663 AFULGI_00008340 ce5c8a7f8bd7c8f7d0e6272ecac7ca44 488 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 53 212 1.0E-14 T 01-11-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like AFULGI_00000600 6760459436dc42c0db2e63798c9e339a 228 TIGRFAM TIGR02593 CRISPR_cas5: CRISPR-associated protein Cas5 3 43 2.6E-10 T 01-11-2018 IPR013422 CRISPR-associated protein Cas5, N-terminal AFULGI_00014440 c707e64471163c2a1b1cd13f55ba63ce 93 Gene3D G3DSA:3.10.450.80 1 92 1.4E-32 T 01-11-2018 AFULGI_00014440 c707e64471163c2a1b1cd13f55ba63ce 93 SUPERFAMILY SSF57829 1 91 2.75E-33 T 01-11-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 AFULGI_00014440 c707e64471163c2a1b1cd13f55ba63ce 93 Hamap MF_01476 50S ribosomal protein L44e [rpl44e]. 1 91 22.568 T 01-11-2018 IPR000552 Ribosomal protein L44e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00014440 c707e64471163c2a1b1cd13f55ba63ce 93 Pfam PF00935 Ribosomal protein L44 16 90 1.3E-25 T 01-11-2018 IPR000552 Ribosomal protein L44e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00014440 c707e64471163c2a1b1cd13f55ba63ce 93 ProDom PD002841 RIBOSOMAL RIBONUCLEOPROTEIN 60S L44 L44E L41 RESISTANCE 50S ANTIBIOTIC CYCLOHEXIMIDE 9 92 1.0E-43 T 01-11-2018 IPR000552 Ribosomal protein L44e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00019010 2cebe793a0a81f036295f02a8549f67b 119 PIRSF PIRSF015873 1 119 5.5E-37 T 01-11-2018 IPR012040 Formylmethanofuran dehydrogenase, subunit D AFULGI_00019010 2cebe793a0a81f036295f02a8549f67b 119 SUPERFAMILY SSF50692 27 108 1.78E-11 T 01-11-2018 IPR009010 Aspartate decarboxylase-like domain superfamily AFULGI_00019010 2cebe793a0a81f036295f02a8549f67b 119 Gene3D G3DSA:2.40.40.20 16 106 8.5E-9 T 01-11-2018 AFULGI_00019010 2cebe793a0a81f036295f02a8549f67b 119 Pfam PF01568 Molydopterin dinucleotide binding domain 25 82 1.0E-8 T 01-11-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 AFULGI_00025160 9b8a0a08adefbe97d745c046f1b8be20 53 SUPERFAMILY SSF47598 4 43 5.41E-6 T 01-11-2018 IPR010985 Ribbon-helix-helix GO:0006355 AFULGI_00025160 9b8a0a08adefbe97d745c046f1b8be20 53 Pfam PF01402 Ribbon-helix-helix protein, copG family 7 42 8.0E-7 T 01-11-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 AFULGI_00025570 45b77e998f0adf8bd710c5c218d119cd 64 ProDom PD053081 COIL MM0410 AF2262 COILED 9 61 3.0E-15 T 01-11-2018 AFULGI_00026440 fd233bdb7576bfabb6ddba9253dde68a 254 SUPERFAMILY SSF52540 3 235 3.74E-45 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00026440 fd233bdb7576bfabb6ddba9253dde68a 254 SMART SM00382 28 220 6.3E-9 T 01-11-2018 IPR003593 AAA+ ATPase domain AFULGI_00026440 fd233bdb7576bfabb6ddba9253dde68a 254 Pfam PF00005 ABC transporter 19 163 3.2E-23 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFULGI_00026440 fd233bdb7576bfabb6ddba9253dde68a 254 Gene3D G3DSA:3.40.50.300 2 240 7.9E-52 T 01-11-2018 AFULGI_00017250 2ba24a318d7e8556f8f43f29b0f18068 133 SMART SM00448 2 117 2.6E-30 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFULGI_00017250 2ba24a318d7e8556f8f43f29b0f18068 133 Pfam PF00072 Response regulator receiver domain 4 115 5.1E-24 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFULGI_00017250 2ba24a318d7e8556f8f43f29b0f18068 133 SUPERFAMILY SSF52172 3 119 2.99E-32 T 01-11-2018 IPR011006 CheY-like superfamily AFULGI_00017250 2ba24a318d7e8556f8f43f29b0f18068 133 Gene3D G3DSA:3.40.50.2300 2 132 2.7E-37 T 01-11-2018 AFULGI_00001900 e0bb80d8cd81b8340891de508001d95a 204 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 47 97 4.4E-11 T 01-11-2018 AFULGI_00001900 e0bb80d8cd81b8340891de508001d95a 204 SUPERFAMILY SSF53335 3 196 1.32E-24 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFULGI_00001900 e0bb80d8cd81b8340891de508001d95a 204 Gene3D G3DSA:3.40.50.150 1 200 1.7E-52 T 01-11-2018 AFULGI_00019670 fcb3bce25f654753adde5b40684887d1 308 Gene3D G3DSA:3.40.50.1820 1 308 2.6E-114 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold AFULGI_00019670 fcb3bce25f654753adde5b40684887d1 308 Pfam PF07859 alpha/beta hydrolase fold 79 285 1.2E-74 T 01-11-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0016787 AFULGI_00019670 fcb3bce25f654753adde5b40684887d1 308 SUPERFAMILY SSF53474 35 305 1.36E-73 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold AFULGI_00007220 fe52f397baababad3977122a2c9955bf 156 PIRSF PIRSF005978 1 156 1.4E-66 T 01-11-2018 IPR016472 Transcription regulator, MJ0621, predicted AFULGI_00007220 fe52f397baababad3977122a2c9955bf 156 Pfam PF01381 Helix-turn-helix 21 67 3.5E-5 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFULGI_00007220 fe52f397baababad3977122a2c9955bf 156 SUPERFAMILY SSF159800 66 155 3.53E-7 T 01-11-2018 AFULGI_00007220 fe52f397baababad3977122a2c9955bf 156 SUPERFAMILY SSF47413 14 67 9.76E-6 T 01-11-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFULGI_00023310 454fd3734cd57972b8c17aecf31a0d2b 105 TIGRFAM TIGR00293 TIGR00293: prefoldin, alpha subunit 7 104 8.2E-30 T 01-11-2018 IPR011599 Prefoldin alpha subunit, archaea-type GO:0006457|GO:0016272|GO:0051082 Reactome: R-HSA-389957 AFULGI_00023310 454fd3734cd57972b8c17aecf31a0d2b 105 SUPERFAMILY SSF46579 7 103 2.22E-19 T 01-11-2018 AFULGI_00023310 454fd3734cd57972b8c17aecf31a0d2b 105 Pfam PF02996 Prefoldin subunit 17 104 9.1E-23 T 01-11-2018 IPR004127 Prefoldin alpha-like AFULGI_00023310 454fd3734cd57972b8c17aecf31a0d2b 105 Gene3D G3DSA:1.10.287.370 6 105 4.3E-26 T 01-11-2018 IPR009053 Prefoldin AFULGI_00003010 f3cd608902d53672ef697334fc80a7e6 418 Gene3D G3DSA:3.40.50.300 4 248 2.3E-17 T 01-11-2018 AFULGI_00003010 f3cd608902d53672ef697334fc80a7e6 418 SUPERFAMILY SSF52540 7 246 1.47E-21 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00010730 ebd170645f57131039e9dd030b9528e4 66 Gene3D G3DSA:3.30.450.20 1 64 5.2E-7 T 01-11-2018 AFULGI_00010730 ebd170645f57131039e9dd030b9528e4 66 SUPERFAMILY SSF55785 6 60 3.05E-7 T 01-11-2018 IPR035965 PAS domain superfamily AFULGI_00020610 960cfbdd8d12cededb755ec9b2f4442f 380 SMART SM00729 83 297 1.5E-7 T 01-11-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 AFULGI_00020610 960cfbdd8d12cededb755ec9b2f4442f 380 SUPERFAMILY SSF102114 79 297 1.16E-34 T 01-11-2018 AFULGI_00020610 960cfbdd8d12cededb755ec9b2f4442f 380 Pfam PF04055 Radical SAM superfamily 91 252 1.3E-23 T 01-11-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFULGI_00020610 960cfbdd8d12cededb755ec9b2f4442f 380 Gene3D G3DSA:3.20.20.70 79 357 4.7E-34 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFULGI_00014570 1baaae31fcbb4bdb7bcd46da5d3ed820 95 Gene3D G3DSA:3.30.1980.10 1 95 1.0E-30 T 01-11-2018 IPR036493 Hypothetical protein YunC superfamily AFULGI_00014570 1baaae31fcbb4bdb7bcd46da5d3ed820 95 SUPERFAMILY SSF102891 1 95 4.58E-32 T 01-11-2018 IPR036493 Hypothetical protein YunC superfamily AFULGI_00014570 1baaae31fcbb4bdb7bcd46da5d3ed820 95 Pfam PF08827 Domain of unknown function (DUF1805) 37 95 8.7E-21 T 01-11-2018 IPR014931 Protein of unknown function DUF1805 AFULGI_00002140 bd0183e03f4c61f1cb25ba857b3a719f 196 SUPERFAMILY SSF51569 14 195 1.46E-43 T 01-11-2018 AFULGI_00002140 bd0183e03f4c61f1cb25ba857b3a719f 196 Pfam PF01487 Type I 3-dehydroquinase 13 191 3.2E-34 T 01-11-2018 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 AFULGI_00002140 bd0183e03f4c61f1cb25ba857b3a719f 196 Gene3D G3DSA:3.20.20.70 1 196 5.6E-74 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFULGI_00002140 bd0183e03f4c61f1cb25ba857b3a719f 196 Hamap MF_00214 3-dehydroquinate dehydratase [aroD]. 2 195 34.831 T 01-11-2018 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 AFULGI_00002140 bd0183e03f4c61f1cb25ba857b3a719f 196 TIGRFAM TIGR01093 aroD: 3-dehydroquinate dehydratase, type I 8 191 4.3E-55 T 01-11-2018 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 AFULGI_00013870 7a388ab9c88dac251d2d196befdb7966 256 Gene3D G3DSA:3.20.20.150 9 256 4.7E-39 T 01-11-2018 AFULGI_00013870 7a388ab9c88dac251d2d196befdb7966 256 Pfam PF01261 Xylose isomerase-like TIM barrel 20 220 2.4E-13 T 01-11-2018 IPR013022 Xylose isomerase-like, TIM barrel domain AFULGI_00013870 7a388ab9c88dac251d2d196befdb7966 256 SUPERFAMILY SSF51658 5 253 7.05E-30 T 01-11-2018 IPR036237 Xylose isomerase-like superfamily AFULGI_00016350 04ffaa8a143998f3175f5c120f85d9c6 368 Pfam PF07728 AAA domain (dynein-related subfamily) 38 165 5.4E-25 T 01-11-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 AFULGI_00016350 04ffaa8a143998f3175f5c120f85d9c6 368 Gene3D G3DSA:3.40.50.300 2 212 3.1E-52 T 01-11-2018 AFULGI_00016350 04ffaa8a143998f3175f5c120f85d9c6 368 SMART SM00382 35 172 2.5E-5 T 01-11-2018 IPR003593 AAA+ ATPase domain AFULGI_00016350 04ffaa8a143998f3175f5c120f85d9c6 368 Gene3D G3DSA:1.10.8.300 213 271 7.0E-11 T 01-11-2018 AFULGI_00016350 04ffaa8a143998f3175f5c120f85d9c6 368 SUPERFAMILY SSF52540 17 217 6.32E-19 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00026210 db047dda9209839545fd17e8efe64459 181 SUPERFAMILY SSF53448 2 176 5.01E-17 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFULGI_00026210 db047dda9209839545fd17e8efe64459 181 TIGRFAM TIGR00454 TIGR00454: TIGR00454 family protein 1 168 5.3E-76 T 01-11-2018 IPR005245 Conserved hypothetical protein CHP00454 KEGG: 00860+2.7.7.62|MetaCyc: PWY-6269|MetaCyc: PWY-7962|MetaCyc: PWY-7971|MetaCyc: PWY-7972 AFULGI_00026210 db047dda9209839545fd17e8efe64459 181 Pfam PF12804 MobA-like NTP transferase domain 4 101 2.2E-11 T 01-11-2018 IPR025877 MobA-like NTP transferase AFULGI_00026210 db047dda9209839545fd17e8efe64459 181 Gene3D G3DSA:3.90.550.10 3 171 2.1E-27 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFULGI_00005870 08e23902928a085c5cc226fff1e5b9bd 109 Gene3D G3DSA:1.10.10.10 3 89 3.4E-18 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00005870 08e23902928a085c5cc226fff1e5b9bd 109 SUPERFAMILY SSF46785 6 107 3.43E-18 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00005870 08e23902928a085c5cc226fff1e5b9bd 109 Pfam PF01638 HxlR-like helix-turn-helix 9 73 1.4E-10 T 01-11-2018 IPR002577 Helix-turn-helix, HxlR type AFULGI_00011510 a890fb4f29ca48dc0b4978b750a7da88 200 TIGRFAM TIGR02537 arch_flag_Nterm: archaeal flagellin N-terminal-like domain 8 28 9.4E-4 T 01-11-2018 IPR013373 Flagellin/pilin, N-terminal AFULGI_00011510 a890fb4f29ca48dc0b4978b750a7da88 200 Pfam PF01917 Archaebacterial flagellin 9 185 3.5E-44 T 01-11-2018 IPR002774 Flagellin, archaea GO:0005198|GO:0006928 AFULGI_00010000 d3e2368576fe294a856ef1e26708f96f 101 SUPERFAMILY SSF55159 2 98 2.88E-29 T 01-11-2018 IPR036877 SUI1 domain superfamily GO:0003743|GO:0006413 AFULGI_00010000 d3e2368576fe294a856ef1e26708f96f 101 TIGRFAM TIGR01158 SUI1_rel: putative translation initiation factor SUI1 3 100 4.0E-39 T 01-11-2018 IPR005872 Archaeal/bacterial translation initiation factor SUI1 GO:0003743 AFULGI_00010000 d3e2368576fe294a856ef1e26708f96f 101 Gene3D G3DSA:3.30.780.10 24 101 2.6E-28 T 01-11-2018 AFULGI_00010000 d3e2368576fe294a856ef1e26708f96f 101 Pfam PF01253 Translation initiation factor SUI1 24 94 2.2E-21 T 01-11-2018 IPR001950 SUI1 domain GO:0003743|GO:0006413 AFULGI_00010000 d3e2368576fe294a856ef1e26708f96f 101 PIRSF PIRSF037511 1 101 8.9E-30 T 01-11-2018 IPR005872 Archaeal/bacterial translation initiation factor SUI1 GO:0003743 AFULGI_00010000 d3e2368576fe294a856ef1e26708f96f 101 Hamap MF_00604 Protein translation factor SUI1 homolog. 6 97 29.761 T 01-11-2018 IPR022851 Translation factor SUI1 homolog, archaea AFULGI_00003860 604ff0d8a6da63296b08b1907b7d4a8d 166 Gene3D G3DSA:3.40.50.1010 1 125 1.4E-29 T 01-11-2018 AFULGI_00003860 604ff0d8a6da63296b08b1907b7d4a8d 166 Pfam PF17146 PIN domain of ribonuclease 8 86 1.3E-17 T 01-11-2018 IPR033411 Ribonuclease, PIN domain Reactome: R-HSA-6791226 AFULGI_00003860 604ff0d8a6da63296b08b1907b7d4a8d 166 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 7 151 9.654 T 01-11-2018 IPR022907 VapC family GO:0004540 AFULGI_00005820 e011e447503bf856a288de7ff1e307da 154 Pfam PF00501 AMP-binding enzyme 39 130 2.3E-18 T 01-11-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFULGI_00005820 e011e447503bf856a288de7ff1e307da 154 SUPERFAMILY SSF56801 32 134 6.28E-23 T 01-11-2018 AFULGI_00005820 e011e447503bf856a288de7ff1e307da 154 Gene3D G3DSA:3.40.50.980 22 153 3.4E-24 T 01-11-2018 AFULGI_00010480 152fc89d022c2a3211462ca9a532db2a 218 SMART SM00382 26 198 8.5E-11 T 01-11-2018 IPR003593 AAA+ ATPase domain AFULGI_00010480 152fc89d022c2a3211462ca9a532db2a 218 Pfam PF00005 ABC transporter 17 150 1.5E-26 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFULGI_00010480 152fc89d022c2a3211462ca9a532db2a 218 Gene3D G3DSA:3.40.50.300 1 217 1.6E-46 T 01-11-2018 AFULGI_00010480 152fc89d022c2a3211462ca9a532db2a 218 SUPERFAMILY SSF52540 2 208 3.0E-46 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00010480 152fc89d022c2a3211462ca9a532db2a 218 ProSitePatterns PS00211 ABC transporters family signature. 123 137 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFULGI_00010370 e69e97942b22cd6ef49361dad3994132 126 Gene3D G3DSA:1.20.120.580 1 123 2.5E-8 T 01-11-2018 IPR037038 Bsu32300-like superfamily AFULGI_00010370 e69e97942b22cd6ef49361dad3994132 126 Pfam PF01934 Protein of unknown function DUF86 4 99 1.0E-18 T 01-11-2018 IPR008201 Protein of unknown function DUF86 AFULGI_00014320 3ba69a70181f2fb6d1a915ebfa73c983 287 Gene3D G3DSA:3.40.50.620 1 287 4.5E-64 T 01-11-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFULGI_00014320 3ba69a70181f2fb6d1a915ebfa73c983 287 Pfam PF01171 PP-loop family 50 205 1.1E-11 T 01-11-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 AFULGI_00014320 3ba69a70181f2fb6d1a915ebfa73c983 287 SUPERFAMILY SSF52402 25 227 5.95E-38 T 01-11-2018 AFULGI_00014320 3ba69a70181f2fb6d1a915ebfa73c983 287 PIRSF PIRSF004976 1 287 3.9E-84 T 01-11-2018 IPR035107 tRNA thiolation protein, TtcA/Ctu1 type GO:0008033 Reactome: R-HSA-6782315 AFULGI_00017750 04032062b3c7293657050bedf555e4f9 192 SMART SM00506 13 156 3.3E-52 T 01-11-2018 IPR002589 Macro domain AFULGI_00017750 04032062b3c7293657050bedf555e4f9 192 SUPERFAMILY SSF52949 4 189 2.35E-50 T 01-11-2018 AFULGI_00017750 04032062b3c7293657050bedf555e4f9 192 Gene3D G3DSA:3.40.220.10 1 192 5.4E-62 T 01-11-2018 AFULGI_00017750 04032062b3c7293657050bedf555e4f9 192 Pfam PF01661 Macro domain 30 155 5.7E-31 T 01-11-2018 IPR002589 Macro domain AFULGI_00013300 5f66f5f7d8e92358815d157ef8c2905d 231 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 6 71 1.8E-22 T 01-11-2018 IPR002831 Transcription regulator TrmB, N-terminal AFULGI_00013300 5f66f5f7d8e92358815d157ef8c2905d 231 Gene3D G3DSA:1.10.10.10 1 98 2.3E-25 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00013300 5f66f5f7d8e92358815d157ef8c2905d 231 SUPERFAMILY SSF46785 2 93 2.27E-10 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00021970 32e4690c27ee05f0174c81838cdc6d9a 252 Gene3D G3DSA:3.40.50.300 3 226 5.3E-46 T 01-11-2018 AFULGI_00021970 32e4690c27ee05f0174c81838cdc6d9a 252 SUPERFAMILY SSF52540 4 226 4.84E-41 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00021970 32e4690c27ee05f0174c81838cdc6d9a 252 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 5 206 7.0E-19 T 01-11-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain AFULGI_00018430 f5ce9875aea9c1c033f8990f5399fb56 312 SUPERFAMILY SSF46785 3 60 7.15E-5 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00018430 f5ce9875aea9c1c033f8990f5399fb56 312 Gene3D G3DSA:3.30.70.3460 192 312 1.6E-17 T 01-11-2018 AFULGI_00018430 f5ce9875aea9c1c033f8990f5399fb56 312 Gene3D G3DSA:3.30.70.3460 64 158 1.9E-15 T 01-11-2018 AFULGI_00000360 3c6008f58a6813375cbaffb64a341be9 165 TIGRFAM TIGR04088 cognate_SipW: SipW-cognate class signal peptide 9 40 6.5E-8 T 01-11-2018 IPR023833 Signal peptide, camelysin AFULGI_00023150 056251dfde16109a187333733085790b 426 Pfam PF00303 Thymidylate synthase 286 411 7.7E-16 T 01-11-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 AFULGI_00023150 056251dfde16109a187333733085790b 426 SUPERFAMILY SSF55831 197 415 3.79E-44 T 01-11-2018 IPR036926 Thymidylate synthase/dCMP hydroxymethylase superfamily KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 AFULGI_00023150 056251dfde16109a187333733085790b 426 Gene3D G3DSA:3.30.572.10 219 422 5.6E-26 T 01-11-2018 IPR036926 Thymidylate synthase/dCMP hydroxymethylase superfamily KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 AFULGI_00023150 056251dfde16109a187333733085790b 426 Gene3D G3DSA:3.30.572.10 51 181 9.9E-8 T 01-11-2018 IPR036926 Thymidylate synthase/dCMP hydroxymethylase superfamily KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 AFULGI_00023150 056251dfde16109a187333733085790b 426 SUPERFAMILY SSF55831 2 203 2.62E-29 T 01-11-2018 IPR036926 Thymidylate synthase/dCMP hydroxymethylase superfamily KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 AFULGI_00015510 7e66ada9b589622d96f0768fef944624 308 Gene3D G3DSA:3.40.50.1000 2 257 3.3E-101 T 01-11-2018 IPR023214 HAD superfamily AFULGI_00015510 7e66ada9b589622d96f0768fef944624 308 SUPERFAMILY SSF56784 1 263 6.01E-43 T 01-11-2018 IPR036412 HAD-like superfamily AFULGI_00015510 7e66ada9b589622d96f0768fef944624 308 Gene3D G3DSA:1.10.3870.10 14 182 3.3E-101 T 01-11-2018 AFULGI_00015510 7e66ada9b589622d96f0768fef944624 308 Gene3D G3DSA:1.20.5.1100 281 308 6.8E-20 T 01-11-2018 AFULGI_00015510 7e66ada9b589622d96f0768fef944624 308 PIRSF PIRSF019370 1 308 1.6E-143 T 01-11-2018 IPR024196 [NiFe]-hydrogenase-3-type complex Eha, EhaR AFULGI_00015910 f6804123d78df56464a0ff4cd01cdebd 963 Gene3D G3DSA:2.60.40.10 733 819 4.6E-7 T 01-11-2018 IPR013783 Immunoglobulin-like fold AFULGI_00015910 f6804123d78df56464a0ff4cd01cdebd 963 Gene3D G3DSA:2.60.40.10 820 910 1.7E-7 T 01-11-2018 IPR013783 Immunoglobulin-like fold AFULGI_00015910 f6804123d78df56464a0ff4cd01cdebd 963 TIGRFAM TIGR04126 PGF_CTERM: PGF-CTERM archaeal protein-sorting signal 940 963 9.1E-7 T 01-11-2018 IPR026371 PGF-CTERM archaeal protein-sorting signal AFULGI_00004760 944cbaf13b3968273dfb72696241916e 267 SUPERFAMILY SSF52518 14 215 8.76E-75 T 01-11-2018 IPR029061 Thiamin diphosphate-binding fold AFULGI_00004760 944cbaf13b3968273dfb72696241916e 267 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 50 197 2.5E-40 T 01-11-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 AFULGI_00004760 944cbaf13b3968273dfb72696241916e 267 Gene3D G3DSA:3.40.50.970 24 204 8.1E-33 T 01-11-2018 AFULGI_00002430 7693380523bca5e211e3e413c84b97f9 84 SUPERFAMILY SSF46785 5 70 2.79E-10 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00002430 7693380523bca5e211e3e413c84b97f9 84 Gene3D G3DSA:1.10.10.10 2 83 2.3E-15 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00008910 5274c32346196b5afb9b4e6eeedecf57 544 TIGRFAM TIGR00795 lctP: transporter, lactate permease (LctP) family 2 537 1.1E-190 T 01-11-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 AFULGI_00008910 5274c32346196b5afb9b4e6eeedecf57 544 Pfam PF02652 L-lactate permease 1 534 1.7E-190 T 01-11-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 AFULGI_00012020 d075f6a8664fda006d4a08f5dbb2779a 191 Pfam PF04071 Cysteine-rich small domain 24 89 5.6E-21 T 01-11-2018 IPR007212 Cysteine-rich small domain AFULGI_00009150 d82f05dde2389c38f541d8e1055baa4f 183 SUPERFAMILY SSF48371 11 150 1.88E-6 T 01-11-2018 IPR016024 Armadillo-type fold AFULGI_00012120 06ae0ffd7e598825c53ef8ac87954e8c 186 Pfam PF04019 Protein of unknown function (DUF359) 49 171 4.4E-36 T 01-11-2018 IPR007164 Protein of unknown function DUF359 AFULGI_00012120 06ae0ffd7e598825c53ef8ac87954e8c 186 PIRSF PIRSF006533 1 175 5.5E-61 T 01-11-2018 IPR007164 Protein of unknown function DUF359 AFULGI_00012120 06ae0ffd7e598825c53ef8ac87954e8c 186 Hamap MF_00590 UPF0218 protein . 6 173 28.141 T 01-11-2018 IPR007164 Protein of unknown function DUF359 AFULGI_00026470 e15d05b2662ef74e101275b0928c96bc 373 Gene3D G3DSA:3.90.1150.10 24 363 1.1E-106 T 01-11-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFULGI_00026470 e15d05b2662ef74e101275b0928c96bc 373 Pfam PF00155 Aminotransferase class I and II 31 365 4.4E-64 T 01-11-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 AFULGI_00026470 e15d05b2662ef74e101275b0928c96bc 373 Gene3D G3DSA:3.40.640.10 62 271 1.1E-106 T 01-11-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFULGI_00026470 e15d05b2662ef74e101275b0928c96bc 373 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 221 234 - T 01-11-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 AFULGI_00026470 e15d05b2662ef74e101275b0928c96bc 373 SUPERFAMILY SSF53383 4 368 1.45E-102 T 01-11-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFULGI_00006950 55402720ec5e123c50c026b6018c612e 533 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 70 199 1.8E-14 T 01-11-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like AFULGI_00015750 ebd9952c0b73e255bcd3fd9f938e3123 621 Pfam PF01935 Domain of unknown function DUF87 260 462 3.8E-6 T 01-11-2018 IPR002789 Helicase HerA, central domain AFULGI_00015750 ebd9952c0b73e255bcd3fd9f938e3123 621 Gene3D G3DSA:3.40.50.300 260 602 1.4E-48 T 01-11-2018 AFULGI_00015750 ebd9952c0b73e255bcd3fd9f938e3123 621 SUPERFAMILY SSF52540 246 570 9.31E-26 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00015750 ebd9952c0b73e255bcd3fd9f938e3123 621 Gene3D G3DSA:1.10.8.730 334 456 1.4E-48 T 01-11-2018 AFULGI_00005680 1cb48ef54934135c9f4fec4e0156cb1f 137 Pfam PF07849 Protein of unknown function (DUF1641) 99 135 1.8E-16 T 01-11-2018 IPR012440 Protein of unknown function DUF1641 AFULGI_00011460 c8c510f08b6451cf39cc6fed7b81b1dd 628 Gene3D G3DSA:3.40.50.300 339 626 1.3E-92 T 01-11-2018 AFULGI_00011460 c8c510f08b6451cf39cc6fed7b81b1dd 628 Pfam PF00437 Type II/IV secretion system protein 241 511 1.1E-43 T 01-11-2018 IPR001482 Type II/IV secretion system protein AFULGI_00011460 c8c510f08b6451cf39cc6fed7b81b1dd 628 SUPERFAMILY SSF52540 221 611 1.72E-61 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00000110 42d5d1c7b8937c1886e128a25dc3a1f8 399 Pfam PF07690 Major Facilitator Superfamily 17 349 1.4E-35 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFULGI_00000110 42d5d1c7b8937c1886e128a25dc3a1f8 399 Gene3D G3DSA:1.20.1250.20 195 397 1.2E-22 T 01-11-2018 AFULGI_00000110 42d5d1c7b8937c1886e128a25dc3a1f8 399 Gene3D G3DSA:1.20.1250.20 6 194 1.1E-25 T 01-11-2018 AFULGI_00000110 42d5d1c7b8937c1886e128a25dc3a1f8 399 SUPERFAMILY SSF103473 5 397 4.32E-58 T 01-11-2018 IPR036259 MFS transporter superfamily AFULGI_00021580 0e987268fb581402ee2ed2f88f1451ef 399 Hamap MF_00007 DNA primase DnaG [dnaG]. 18 397 36.537 T 01-11-2018 IPR020607 DNA primase DnaG, archaea GO:0000178|GO:0003896|GO:0008143 AFULGI_00021580 0e987268fb581402ee2ed2f88f1451ef 399 Pfam PF13662 Toprim domain 182 266 3.9E-13 T 01-11-2018 IPR006171 TOPRIM domain AFULGI_00021580 0e987268fb581402ee2ed2f88f1451ef 399 SMART SM00493 182 251 2.4E-12 T 01-11-2018 IPR006171 TOPRIM domain AFULGI_00021580 0e987268fb581402ee2ed2f88f1451ef 399 Gene3D G3DSA:3.40.1360.10 175 282 1.4E-14 T 01-11-2018 AFULGI_00021580 0e987268fb581402ee2ed2f88f1451ef 399 SUPERFAMILY SSF56731 175 275 2.14E-11 T 01-11-2018 AFULGI_00008120 155212c15315253b65f94e60c4f3061f 163 Pfam PF08241 Methyltransferase domain 28 91 1.8E-4 T 01-11-2018 IPR013216 Methyltransferase type 11 GO:0008168 AFULGI_00008120 155212c15315253b65f94e60c4f3061f 163 Hamap MF_00786 Probable cobalt-precorrin-6B C(15)-methyltransferase (decarboxylating) [cbiT]. 2 163 26.392 T 01-11-2018 IPR023475 Probable cobalt-precorrin-6B C(15)-methyltransferase (decarboxylating) CbiT GO:0008168 KEGG: 00860+2.1.1.196|MetaCyc: PWY-7377 AFULGI_00008120 155212c15315253b65f94e60c4f3061f 163 SUPERFAMILY SSF53335 6 101 1.51E-17 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFULGI_00008120 155212c15315253b65f94e60c4f3061f 163 Gene3D G3DSA:3.40.50.150 1 162 9.4E-32 T 01-11-2018 AFULGI_00013480 399fcb73a679881fb4040569ca8f01e4 129 ProDom PD020987 PF0014 UNCHARACTERIZED AF1250 PH0127 MJ0105 MA4414 ARCHAEAL 1 107 1.0E-56 T 01-11-2018 IPR007417 Protein of unknown function DUF473 AFULGI_00013480 399fcb73a679881fb4040569ca8f01e4 129 Pfam PF04322 Protein of unknown function (DUF473) 1 116 3.5E-42 T 01-11-2018 IPR007417 Protein of unknown function DUF473 AFULGI_00007060 b4c731ee7ec7038a7dbf2b8f6f12a5e0 218 SUPERFAMILY SSF51219 1 217 1.54E-66 T 01-11-2018 IPR016031 Tryptophan RNA-binding attenuator protein-like domain superfamily AFULGI_00007060 b4c731ee7ec7038a7dbf2b8f6f12a5e0 218 TIGRFAM TIGR00266 TIGR00266: TIGR00266 family protein 1 217 1.6E-102 T 01-11-2018 IPR002838 Mitochondrial biogenesis protein AIM24 AFULGI_00007060 b4c731ee7ec7038a7dbf2b8f6f12a5e0 218 Pfam PF01987 Mitochondrial biogenesis AIM24 4 202 9.6E-59 T 01-11-2018 IPR002838 Mitochondrial biogenesis protein AIM24 AFULGI_00007060 b4c731ee7ec7038a7dbf2b8f6f12a5e0 218 Gene3D G3DSA:3.60.160.10 1 218 6.2E-77 T 01-11-2018 IPR036983 Mitochondrial biogenesis AIM24 superfamily AFULGI_00001290 8d97afada9ae58415d37a03866e0ce11 174 Gene3D G3DSA:1.10.12.20 4 76 5.2E-18 T 01-11-2018 AFULGI_00001290 8d97afada9ae58415d37a03866e0ce11 174 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 40 69 1.1E-8 T 01-11-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal AFULGI_00001290 8d97afada9ae58415d37a03866e0ce11 174 SUPERFAMILY SSF50249 31 157 1.2E-20 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold AFULGI_00006510 bff7f4c9efde7c0329e972a6e0d316fa 209 Pfam PF00753 Metallo-beta-lactamase superfamily 9 186 8.6E-36 T 01-11-2018 IPR001279 Metallo-beta-lactamase AFULGI_00006510 bff7f4c9efde7c0329e972a6e0d316fa 209 SUPERFAMILY SSF56281 12 201 2.75E-51 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFULGI_00006510 bff7f4c9efde7c0329e972a6e0d316fa 209 SMART SM00849 12 186 7.8E-41 T 01-11-2018 IPR001279 Metallo-beta-lactamase AFULGI_00006510 bff7f4c9efde7c0329e972a6e0d316fa 209 Gene3D G3DSA:3.60.15.10 4 206 2.5E-52 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFULGI_00019390 053d3158a1a55158dfeaa5e0384aaa95 136 Pfam PF01850 PIN domain 2 122 3.4E-17 T 01-11-2018 IPR002716 PIN domain AFULGI_00019390 053d3158a1a55158dfeaa5e0384aaa95 136 SUPERFAMILY SSF88723 2 124 8.13E-23 T 01-11-2018 IPR029060 PIN-like domain superfamily AFULGI_00019390 053d3158a1a55158dfeaa5e0384aaa95 136 Gene3D G3DSA:3.40.50.1010 1 132 2.5E-25 T 01-11-2018 AFULGI_00006300 c8ef01a04756484cb1825874bcc7e610 285 TIGRFAM TIGR01903 cas5_csm4: CRISPR type III-A/MTUBE-associated RAMP protein Csm4 4 278 4.0E-44 T 01-11-2018 IPR005510 CRISPR type III-associated RAMP protein Csm4 AFULGI_00015430 4cb8a44efec293a06599e60dc752cc43 217 Pfam PF04967 HTH DNA binding domain 150 202 3.8E-20 T 01-11-2018 IPR007050 Bacterioopsin activator-type, HTH domain AFULGI_00000390 dcf4fc824b3280f22fdbaa056a809b58 370 SUPERFAMILY SSF51306 258 350 7.59E-11 T 01-11-2018 IPR036286 LexA/Signal peptidase-like superfamily AFULGI_00000390 dcf4fc824b3280f22fdbaa056a809b58 370 Pfam PF00717 Peptidase S24-like 266 311 1.4E-4 T 01-11-2018 IPR015927 Peptidase S24/S26A/S26B/S26C AFULGI_00000390 dcf4fc824b3280f22fdbaa056a809b58 370 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 322 333 8.5E-5 T 01-11-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 AFULGI_00000390 dcf4fc824b3280f22fdbaa056a809b58 370 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 266 281 8.5E-5 T 01-11-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 AFULGI_00000390 dcf4fc824b3280f22fdbaa056a809b58 370 TIGRFAM TIGR02228 sigpep_I_arch: signal peptidase I 234 357 4.1E-29 T 01-11-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 AFULGI_00009020 4497c76b9320450c6b205cdda9967cf8 414 SUPERFAMILY SSF53474 196 335 2.73E-11 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold AFULGI_00009020 4497c76b9320450c6b205cdda9967cf8 414 Gene3D G3DSA:3.40.50.1820 73 315 2.0E-7 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold AFULGI_00009020 4497c76b9320450c6b205cdda9967cf8 414 Pfam PF03283 Pectinacetylesterase 83 267 2.5E-9 T 01-11-2018 IPR004963 Pectinacetylesterase/NOTUM GO:0016787 Reactome: R-HSA-381426|Reactome: R-HSA-5362798|Reactome: R-HSA-8957275 AFULGI_00012100 25e3bd36fcdc3210ed9a9d65ca0e8e2b 55 Gene3D G3DSA:2.20.25.660 1 53 4.8E-20 T 01-11-2018 IPR038582 S27a-like superfamily Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 AFULGI_00012100 25e3bd36fcdc3210ed9a9d65ca0e8e2b 55 SUPERFAMILY SSF57829 8 55 3.3E-20 T 01-11-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 AFULGI_00012100 25e3bd36fcdc3210ed9a9d65ca0e8e2b 55 SMART SM01402 8 50 2.9E-22 T 01-11-2018 IPR002906 Ribosomal protein S27a GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 AFULGI_00012100 25e3bd36fcdc3210ed9a9d65ca0e8e2b 55 Pfam PF01599 Ribosomal protein S27a 9 50 1.2E-20 T 01-11-2018 IPR002906 Ribosomal protein S27a GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 AFULGI_00012100 25e3bd36fcdc3210ed9a9d65ca0e8e2b 55 Hamap MF_00777 30S ribosomal protein S27ae [rps27ae]. 8 53 18.424 T 01-11-2018 IPR022845 Ribosomal protein S27ae AFULGI_00009280 86eca05520644bf760a10a74be230cd0 293 SUPERFAMILY SSF48452 75 268 2.19E-5 T 01-11-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFULGI_00009280 86eca05520644bf760a10a74be230cd0 293 Gene3D G3DSA:1.25.40.10 111 271 8.2E-6 T 01-11-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFULGI_00003630 a296eba9e4f40eb8ae7e0c2e4936a774 74 Pfam PF01423 LSM domain 7 71 5.0E-20 T 01-11-2018 IPR001163 LSM domain, eukaryotic/archaea-type AFULGI_00003630 a296eba9e4f40eb8ae7e0c2e4936a774 74 PIRSF PIRSF006609 1 74 8.9E-27 T 01-11-2018 IPR016487 Sm-like protein Lsm6/SmF GO:0000398|GO:0005732 Reactome: R-HSA-72163 AFULGI_00003630 a296eba9e4f40eb8ae7e0c2e4936a774 74 SUPERFAMILY SSF50182 2 73 2.52E-18 T 01-11-2018 IPR010920 LSM domain superfamily AFULGI_00003630 a296eba9e4f40eb8ae7e0c2e4936a774 74 Gene3D G3DSA:2.30.30.100 1 74 1.2E-23 T 01-11-2018 AFULGI_00003630 a296eba9e4f40eb8ae7e0c2e4936a774 74 SMART SM00651 5 71 1.0E-20 T 01-11-2018 IPR001163 LSM domain, eukaryotic/archaea-type AFULGI_00001740 fc102741a1088b9bdcaaa9aa054ee824 179 Gene3D G3DSA:1.10.760.10 64 179 3.2E-11 T 01-11-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFULGI_00001740 fc102741a1088b9bdcaaa9aa054ee824 179 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 100 175 2.1E-7 T 01-11-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFULGI_00001740 fc102741a1088b9bdcaaa9aa054ee824 179 SUPERFAMILY SSF46626 10 178 5.73E-12 T 01-11-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFULGI_00008000 27e39b51447abaf3b8d24b50cb6bc6be 212 Pfam PF01902 Diphthamide synthase 4 211 5.4E-94 T 01-11-2018 IPR002761 Diphthamide synthase domain MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 AFULGI_00008000 27e39b51447abaf3b8d24b50cb6bc6be 212 Gene3D G3DSA:3.40.50.620 2 135 1.4E-31 T 01-11-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFULGI_00008000 27e39b51447abaf3b8d24b50cb6bc6be 212 TIGRFAM TIGR00290 MJ0570_dom: MJ0570-related uncharacterized domain 5 209 5.1E-84 T 01-11-2018 IPR002761 Diphthamide synthase domain MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 AFULGI_00008000 27e39b51447abaf3b8d24b50cb6bc6be 212 Gene3D G3DSA:3.90.1490.10 138 206 7.7E-10 T 01-11-2018 AFULGI_00008000 27e39b51447abaf3b8d24b50cb6bc6be 212 SUPERFAMILY SSF52402 2 209 1.44E-56 T 01-11-2018 AFULGI_00015110 44c03ddd4bec13896e751538816ddbe3 188 Pfam PF01955 Adenosylcobinamide amidohydrolase 23 181 4.7E-40 T 01-11-2018 IPR002808 Adenosylcobinamide amidohydrolase, CbiZ AFULGI_00026840 a470138e6dd9cd6ffdea89855cb73d33 114 Gene3D G3DSA:3.40.50.2300 1 114 9.9E-36 T 01-11-2018 AFULGI_00026840 a470138e6dd9cd6ffdea89855cb73d33 114 Pfam PF00072 Response regulator receiver domain 4 110 1.4E-26 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFULGI_00026840 a470138e6dd9cd6ffdea89855cb73d33 114 SUPERFAMILY SSF52172 1 114 4.84E-34 T 01-11-2018 IPR011006 CheY-like superfamily AFULGI_00026840 a470138e6dd9cd6ffdea89855cb73d33 114 SMART SM00448 2 110 1.6E-31 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFULGI_00010830 e652f55680468686af21ded72fdc39a8 436 SUPERFAMILY SSF53822 43 427 1.48E-73 T 01-11-2018 IPR028082 Periplasmic binding protein-like I AFULGI_00010830 e652f55680468686af21ded72fdc39a8 436 Gene3D G3DSA:3.40.50.2300 51 385 1.1E-77 T 01-11-2018 AFULGI_00010830 e652f55680468686af21ded72fdc39a8 436 Pfam PF13458 Periplasmic binding protein 44 403 2.1E-61 T 01-11-2018 IPR028081 Leucine-binding protein domain AFULGI_00010830 e652f55680468686af21ded72fdc39a8 436 Gene3D G3DSA:3.40.50.2300 167 297 1.1E-77 T 01-11-2018 AFULGI_00010930 26da69cf649e0f549976a1e2e323e6b5 218 Gene3D G3DSA:2.60.40.1120 22 93 1.9E-8 T 01-11-2018 AFULGI_00010930 26da69cf649e0f549976a1e2e323e6b5 218 Pfam PF13412 Winged helix-turn-helix DNA-binding 166 205 6.7E-5 T 01-11-2018 AFULGI_00010930 26da69cf649e0f549976a1e2e323e6b5 218 Gene3D G3DSA:1.10.10.10 147 218 1.7E-8 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00010930 26da69cf649e0f549976a1e2e323e6b5 218 SUPERFAMILY SSF49464 22 98 1.02E-7 T 01-11-2018 IPR008969 Carboxypeptidase-like, regulatory domain superfamily AFULGI_00010930 26da69cf649e0f549976a1e2e323e6b5 218 SUPERFAMILY SSF46785 155 217 2.96E-8 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00021350 48f00f3c9a5d03c02e8ba5fccecb0ab9 241 Gene3D G3DSA:1.10.3210.30 1 210 4.3E-22 T 01-11-2018 IPR038257 CRISPR-associated Cas3-type HD domain superfamily AFULGI_00021350 48f00f3c9a5d03c02e8ba5fccecb0ab9 241 TIGRFAM TIGR01596 cas3_HD: CRISPR-associated endonuclease Cas3-HD 16 217 2.3E-14 T 01-11-2018 IPR006483 CRISPR-associated Cas3-type HD domain AFULGI_00007910 a357c0108a2c1710d37b2039f830376f 133 Gene3D G3DSA:2.160.10.10 6 131 7.4E-6 T 01-11-2018 AFULGI_00006530 829f4868b06ae5b656be2a09ee2763ad 343 Gene3D G3DSA:3.20.20.70 3 323 2.9E-33 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFULGI_00006530 829f4868b06ae5b656be2a09ee2763ad 343 SUPERFAMILY SSF102114 7 288 3.66E-33 T 01-11-2018 AFULGI_00006530 829f4868b06ae5b656be2a09ee2763ad 343 Pfam PF04055 Radical SAM superfamily 9 139 4.1E-10 T 01-11-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFULGI_00006530 829f4868b06ae5b656be2a09ee2763ad 343 TIGRFAM TIGR04084 rSAM_AF0577: putative peptide-modifying radical SAM enzyme, AF0577 family 8 343 6.1E-103 T 01-11-2018 IPR023819 Peptide-modifying radical SAM enzyme putative, AF0577 AFULGI_00021410 5a6b6ed0110df906780a695594efcc79 251 PIRSF PIRSF006648 1 250 4.9E-65 T 01-11-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AFULGI_00021410 5a6b6ed0110df906780a695594efcc79 251 PRINTS PR00164 ABC-2 type transport system membrane protein signature 22 43 2.2E-11 T 01-11-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AFULGI_00021410 5a6b6ed0110df906780a695594efcc79 251 PRINTS PR00164 ABC-2 type transport system membrane protein signature 192 211 2.2E-11 T 01-11-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AFULGI_00021410 5a6b6ed0110df906780a695594efcc79 251 PRINTS PR00164 ABC-2 type transport system membrane protein signature 135 159 2.2E-11 T 01-11-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AFULGI_00021410 5a6b6ed0110df906780a695594efcc79 251 PRINTS PR00164 ABC-2 type transport system membrane protein signature 172 191 2.2E-11 T 01-11-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AFULGI_00021410 5a6b6ed0110df906780a695594efcc79 251 TIGRFAM TIGR01247 drrB: daunorubicin resistance ABC transporter membrane protein 10 245 1.9E-119 T 01-11-2018 IPR005942 Daunorubicin resistance ABC transporter membrane protein AFULGI_00021410 5a6b6ed0110df906780a695594efcc79 251 Pfam PF01061 ABC-2 type transporter 3 214 1.8E-40 T 01-11-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 AFULGI_00019210 b3f36c904670fc3309feb9d4a154d1db 137 Pfam PF01842 ACT domain 70 128 2.2E-13 T 01-11-2018 IPR002912 ACT domain AFULGI_00019210 b3f36c904670fc3309feb9d4a154d1db 137 Pfam PF01842 ACT domain 4 60 1.8E-10 T 01-11-2018 IPR002912 ACT domain AFULGI_00019210 b3f36c904670fc3309feb9d4a154d1db 137 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 1 71 0.001 T 01-11-2018 AFULGI_00019210 b3f36c904670fc3309feb9d4a154d1db 137 SUPERFAMILY SSF55021 1 68 1.07E-18 T 01-11-2018 AFULGI_00019210 b3f36c904670fc3309feb9d4a154d1db 137 SUPERFAMILY SSF55021 70 129 1.33E-15 T 01-11-2018 AFULGI_00019210 b3f36c904670fc3309feb9d4a154d1db 137 Gene3D G3DSA:3.30.2130.10 1 136 2.1E-56 T 01-11-2018 AFULGI_00002880 92b0b7daf8cc166c0f61c4eab2965a27 66 SUPERFAMILY SSF141694 1 40 3.92E-15 T 01-11-2018 AFULGI_00002880 92b0b7daf8cc166c0f61c4eab2965a27 66 Gene3D G3DSA:4.10.1150.10 1 66 3.8E-19 T 01-11-2018 IPR024069 AF2212-like domain superfamily AFULGI_00002880 92b0b7daf8cc166c0f61c4eab2965a27 66 Pfam PF01954 Protein of unknown function DUF104 1 61 9.4E-21 T 01-11-2018 IPR008203 Uncharacterised protein family UPF0165 AFULGI_00002270 93c5e13f5ff93a79ce3b18d82178699f 139 ProSitePatterns PS01318 TsaA-like domain signature. 77 88 - T 01-11-2018 IPR023368 Uncharacterised protein family UPF0066, conserved site AFULGI_00002270 93c5e13f5ff93a79ce3b18d82178699f 139 Pfam PF01980 Uncharacterised protein family UPF0066 18 129 1.2E-35 T 01-11-2018 IPR023370 YaeB-like, N-terminal domain AFULGI_00002270 93c5e13f5ff93a79ce3b18d82178699f 139 Gene3D G3DSA:2.40.30.70 1 139 7.8E-56 T 01-11-2018 IPR036414 YaeB, N-terminal domain superfamily AFULGI_00002270 93c5e13f5ff93a79ce3b18d82178699f 139 SUPERFAMILY SSF118196 2 134 1.09E-46 T 01-11-2018 IPR036413 YaeB-like superfamily AFULGI_00002270 93c5e13f5ff93a79ce3b18d82178699f 139 TIGRFAM TIGR00104 tRNA_TsaA: tRNA-Thr(GGU) m(6)t(6)A37 methyltransferase TsaA 1 135 5.3E-65 T 01-11-2018 IPR023370 YaeB-like, N-terminal domain AFULGI_00002870 15743ec3a64df38eb9428f10a08d4c0e 151 SUPERFAMILY SSF88723 4 145 5.61E-15 T 01-11-2018 IPR029060 PIN-like domain superfamily AFULGI_00002870 15743ec3a64df38eb9428f10a08d4c0e 151 Gene3D G3DSA:3.40.50.1010 4 147 4.2E-10 T 01-11-2018 AFULGI_00002870 15743ec3a64df38eb9428f10a08d4c0e 151 Pfam PF01850 PIN domain 4 142 3.3E-23 T 01-11-2018 IPR002716 PIN domain AFULGI_00016290 538fc9d2a494511c4ee9d546f160c0c0 134 Pfam PF01909 Nucleotidyltransferase domain 17 85 1.2E-6 T 01-11-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 AFULGI_00016290 538fc9d2a494511c4ee9d546f160c0c0 134 SUPERFAMILY SSF81301 10 111 2.11E-15 T 01-11-2018 AFULGI_00016290 538fc9d2a494511c4ee9d546f160c0c0 134 Gene3D G3DSA:3.30.460.10 5 97 3.0E-12 T 01-11-2018 AFULGI_00017960 8be2ed8de9b193d96f6d19e8f8c4de5d 101 Gene3D G3DSA:1.10.10.10 1 101 3.2E-24 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00017960 8be2ed8de9b193d96f6d19e8f8c4de5d 101 Pfam PF03551 Transcriptional regulator PadR-like family 15 83 5.0E-19 T 01-11-2018 IPR005149 Transcription regulator PadR, N-terminal AFULGI_00017960 8be2ed8de9b193d96f6d19e8f8c4de5d 101 SUPERFAMILY SSF46785 3 98 5.09E-30 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00003050 92c3ba834a379ae88c0f2a6faa85cd75 280 SUPERFAMILY SSF53335 11 180 8.55E-31 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFULGI_00003050 92c3ba834a379ae88c0f2a6faa85cd75 280 Gene3D G3DSA:3.40.50.150 3 227 1.1E-67 T 01-11-2018 AFULGI_00003050 92c3ba834a379ae88c0f2a6faa85cd75 280 Pfam PF13578 Methyltransferase domain 42 142 1.7E-7 T 01-11-2018 AFULGI_00002100 5b631ff4ab5e8b473a08b0e345afef47 284 Pfam PF02653 Branched-chain amino acid transport system / permease component 10 272 9.1E-45 T 01-11-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 AFULGI_00009100 4086a0ff32a502308ffac9a260be8efd 323 Pfam PF02653 Branched-chain amino acid transport system / permease component 26 291 2.6E-49 T 01-11-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 AFULGI_00010590 41f02dc28dcbce9fc0d6f3e8f6e5a7b8 531 Gene3D G3DSA:1.20.1730.10 24 528 9.4E-59 T 01-11-2018 IPR038377 Sodium/glucose symporter superfamily AFULGI_00010590 41f02dc28dcbce9fc0d6f3e8f6e5a7b8 531 Pfam PF00474 Sodium:solute symporter family 36 450 8.2E-50 T 01-11-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 AFULGI_00018050 f6a1f0878a3ab9f1fa6fd4565686736b 292 Gene3D G3DSA:1.10.600.10 1 291 3.4E-81 T 01-11-2018 IPR008949 Isoprenoid synthase domain superfamily AFULGI_00018050 f6a1f0878a3ab9f1fa6fd4565686736b 292 SUPERFAMILY SSF48576 13 278 2.88E-59 T 01-11-2018 IPR008949 Isoprenoid synthase domain superfamily AFULGI_00018050 f6a1f0878a3ab9f1fa6fd4565686736b 292 Pfam PF00348 Polyprenyl synthetase 28 211 6.6E-47 T 01-11-2018 IPR000092 Polyprenyl synthetase GO:0008299 AFULGI_00018450 fc3aaa3b87a9eb3287453153c490d6a3 56 Pfam PF13601 Winged helix DNA-binding domain 5 49 1.9E-7 T 01-11-2018 IPR027395 Winged helix DNA-binding domain AFULGI_00018450 fc3aaa3b87a9eb3287453153c490d6a3 56 SUPERFAMILY SSF46785 2 49 8.52E-10 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00018450 fc3aaa3b87a9eb3287453153c490d6a3 56 Gene3D G3DSA:1.10.10.10 1 55 3.1E-11 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00009450 8ab4ca3d834406ab2cee85d2355f4d33 480 SUPERFAMILY SSF103365 4 480 3.92E-177 T 01-11-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 AFULGI_00009450 8ab4ca3d834406ab2cee85d2355f4d33 480 Pfam PF01139 tRNA-splicing ligase RtcB 46 480 3.3E-173 T 01-11-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 AFULGI_00009450 8ab4ca3d834406ab2cee85d2355f4d33 480 Gene3D G3DSA:3.90.1860.10 2 480 2.8E-206 T 01-11-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 AFULGI_00011740 3b57552def87a598f5edf4ef1b9ecfb1 64 SUPERFAMILY SSF141694 1 60 1.86E-16 T 01-11-2018 AFULGI_00011740 3b57552def87a598f5edf4ef1b9ecfb1 64 Gene3D G3DSA:4.10.1150.10 1 63 7.1E-20 T 01-11-2018 IPR024069 AF2212-like domain superfamily AFULGI_00011740 3b57552def87a598f5edf4ef1b9ecfb1 64 Pfam PF01954 Protein of unknown function DUF104 1 57 4.0E-23 T 01-11-2018 IPR008203 Uncharacterised protein family UPF0165 AFULGI_00017130 e01965a13402b4e507dc35b5844a6e12 90 Pfam PF14947 Winged helix-turn-helix 3 85 1.3E-18 T 01-11-2018 IPR038723 ArnR1-like, winged helix-turn-helix domain AFULGI_00017130 e01965a13402b4e507dc35b5844a6e12 90 SUPERFAMILY SSF46785 4 88 2.3E-13 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00017130 e01965a13402b4e507dc35b5844a6e12 90 Gene3D G3DSA:1.10.10.10 1 89 1.2E-24 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00011610 861570bbab90808b07cace9114bf9bdf 174 TIGRFAM TIGR00288 TIGR00288: TIGR00288 family protein 3 159 2.8E-86 T 01-11-2018 IPR002790 Conserved hypothetical protein CHP00288 AFULGI_00011610 861570bbab90808b07cace9114bf9bdf 174 Pfam PF01936 NYN domain 24 155 6.2E-25 T 01-11-2018 IPR021139 NYN domain, limkain-b1-type AFULGI_00011610 861570bbab90808b07cace9114bf9bdf 174 ProDom PD010896 FAMILY DUF88 ARCHAEBACTERIAL PROTEIN MJ0482 PH0073 PF2040 VNG1608C MA3857 PF2039 25 97 2.0E-35 T 01-11-2018 AFULGI_00011610 861570bbab90808b07cace9114bf9bdf 174 Gene3D G3DSA:3.40.50.1010 15 159 1.1E-16 T 01-11-2018 AFULGI_00007310 d74b60f57f16e9a9041ed3b8bded63e9 76 Gene3D G3DSA:3.30.70.920 4 72 3.7E-19 T 01-11-2018 AFULGI_00007310 d74b60f57f16e9a9041ed3b8bded63e9 76 SUPERFAMILY SSF54909 2 72 2.91E-14 T 01-11-2018 IPR011008 Dimeric alpha-beta barrel AFULGI_00007310 d74b60f57f16e9a9041ed3b8bded63e9 76 Pfam PF01037 Lrp/AsnC ligand binding domain 7 72 1.1E-12 T 01-11-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain AFULGI_00002800 10281cdb88f8082d4d6010d681ba78af 247 SMART SM00893 23 210 1.4E-44 T 01-11-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 AFULGI_00002800 10281cdb88f8082d4d6010d681ba78af 247 Pfam PF01012 Electron transfer flavoprotein domain 30 204 3.0E-45 T 01-11-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 AFULGI_00002800 10281cdb88f8082d4d6010d681ba78af 247 PIRSF PIRSF000090 1 247 3.1E-74 T 01-11-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 AFULGI_00002800 10281cdb88f8082d4d6010d681ba78af 247 SUPERFAMILY SSF52402 1 242 5.58E-67 T 01-11-2018 AFULGI_00002800 10281cdb88f8082d4d6010d681ba78af 247 ProSitePatterns PS01065 Electron transfer flavoprotein beta-subunit signature. 153 174 - T 01-11-2018 IPR000049 Electron transfer flavoprotein, beta-subunit, conserved site GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 AFULGI_00002800 10281cdb88f8082d4d6010d681ba78af 247 Gene3D G3DSA:3.40.50.620 1 245 1.8E-75 T 01-11-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFULGI_00012920 a2fe75c5d688abcdb783011b75edca25 193 TIGRFAM TIGR00024 SbcD_rel_arch: putative phosphoesterase 1 193 1.3E-73 T 01-11-2018 IPR004376 Conserved hypothetical protein CHP00024, phosphoesterase-like AFULGI_00012920 a2fe75c5d688abcdb783011b75edca25 193 Pfam PF00149 Calcineurin-like phosphoesterase 14 118 6.3E-8 T 01-11-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 AFULGI_00012920 a2fe75c5d688abcdb783011b75edca25 193 SUPERFAMILY SSF56300 14 127 2.59E-14 T 01-11-2018 AFULGI_00012920 a2fe75c5d688abcdb783011b75edca25 193 Gene3D G3DSA:3.60.21.10 11 178 4.7E-10 T 01-11-2018 IPR029052 Metallo-dependent phosphatase-like AFULGI_00015210 2572105dd30f40cd29491d3f588cea34 966 SUPERFAMILY SSF53335 413 776 4.46E-51 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFULGI_00015210 2572105dd30f40cd29491d3f588cea34 966 Pfam PF01555 DNA methylase 445 758 7.5E-41 T 01-11-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 AFULGI_00015210 2572105dd30f40cd29491d3f588cea34 966 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 705 727 1.2E-14 T 01-11-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 AFULGI_00015210 2572105dd30f40cd29491d3f588cea34 966 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 728 742 1.2E-14 T 01-11-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 AFULGI_00015210 2572105dd30f40cd29491d3f588cea34 966 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 445 457 1.2E-14 T 01-11-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 AFULGI_00015210 2572105dd30f40cd29491d3f588cea34 966 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 480 499 1.2E-14 T 01-11-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 AFULGI_00015210 2572105dd30f40cd29491d3f588cea34 966 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 448 454 - T 01-11-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 AFULGI_00009850 6ff2e6027ed8498edda724e72aea3085 274 ProDom PD038341 HYDROLASE COFACTOR MOLYBDENUM BIOSYNTHESIS METAL-DEPENDENT DEOXYRIBONUCLEASE PREDICTED TATD-RELATED TVG0313409 A 101 273 7.0E-97 T 01-11-2018 AFULGI_00009850 6ff2e6027ed8498edda724e72aea3085 274 Pfam PF01026 TatD related DNase 5 268 7.5E-29 T 01-11-2018 IPR001130 TatD family GO:0016788 AFULGI_00009850 6ff2e6027ed8498edda724e72aea3085 274 PIRSF PIRSF004961 1 274 3.4E-114 T 01-11-2018 IPR011589 Protein of unknown function UCP004961 AFULGI_00009850 6ff2e6027ed8498edda724e72aea3085 274 SUPERFAMILY SSF51556 2 270 3.12E-24 T 01-11-2018 IPR032466 Metal-dependent hydrolase AFULGI_00009850 6ff2e6027ed8498edda724e72aea3085 274 Gene3D G3DSA:3.20.20.140 3 273 1.6E-20 T 01-11-2018 AFULGI_00011490 2ccf5af94d3303535da9dd47f7bb0311 162 ProDom PD095203 PRECURSOR SIGNAL MA3079 MM0320 AF1052 MA3059 28 161 1.0E-72 T 01-11-2018 AFULGI_00011490 2ccf5af94d3303535da9dd47f7bb0311 162 Pfam PF01917 Archaebacterial flagellin 3 157 2.0E-22 T 01-11-2018 IPR002774 Flagellin, archaea GO:0005198|GO:0006928 AFULGI_00024290 6c1681e02c89a71bc6f58d8382b18dd1 301 PIRSF PIRSF012886 8 301 3.4E-153 T 01-11-2018 IPR016604 Uncharacterised conserved protein UCP012886 AFULGI_00017320 bfb3a26a97b6851b9b4f55977cfd7b0d 69 Hamap MF_00794 Putative antitoxin . 1 69 15.123 T 01-11-2018 IPR003847 Putative antitoxin AFULGI_00017320 bfb3a26a97b6851b9b4f55977cfd7b0d 69 Pfam PF02697 Putative antitoxin 2 64 5.7E-22 T 01-11-2018 IPR003847 Putative antitoxin AFULGI_00017320 bfb3a26a97b6851b9b4f55977cfd7b0d 69 ProDom PD188822 UPF0330 AF1997 ST1125.1 AF1689 AF1478 C1_0043 PYRAB04040 PF1222 MM2475 MA1514 2 65 5.0E-28 T 01-11-2018 IPR003847 Putative antitoxin AFULGI_00002190 68828cbb7480faa4a9cda366150a7205 133 Pfam PF00753 Metallo-beta-lactamase superfamily 7 129 5.1E-22 T 01-11-2018 IPR001279 Metallo-beta-lactamase AFULGI_00002190 68828cbb7480faa4a9cda366150a7205 133 SMART SM00849 7 131 2.5E-8 T 01-11-2018 IPR001279 Metallo-beta-lactamase AFULGI_00002190 68828cbb7480faa4a9cda366150a7205 133 Gene3D G3DSA:3.60.15.10 2 131 3.9E-30 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFULGI_00002190 68828cbb7480faa4a9cda366150a7205 133 SUPERFAMILY SSF56281 7 129 6.94E-28 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFULGI_00016930 02ae7a1262136ba5c437eb94b3e038e6 240 Gene3D G3DSA:1.10.10.10 152 235 8.0E-7 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00016930 02ae7a1262136ba5c437eb94b3e038e6 240 SUPERFAMILY SSF46785 185 224 6.02E-7 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00016930 02ae7a1262136ba5c437eb94b3e038e6 240 Pfam PF01022 Bacterial regulatory protein, arsR family 183 205 1.5E-4 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFULGI_00025610 194cc61e9060df924dc9b9ce57292d59 154 TIGRFAM TIGR02286 PaaD: phenylacetic acid degradation protein PaaD 36 146 1.3E-35 T 01-11-2018 IPR011973 Phenylacetic acid degradation protein PaaD GO:0016790 AFULGI_00025610 194cc61e9060df924dc9b9ce57292d59 154 SUPERFAMILY SSF54637 18 149 2.44E-28 T 01-11-2018 IPR029069 HotDog domain superfamily AFULGI_00025610 194cc61e9060df924dc9b9ce57292d59 154 Pfam PF03061 Thioesterase superfamily 63 136 2.6E-14 T 01-11-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 AFULGI_00025610 194cc61e9060df924dc9b9ce57292d59 154 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 32 144 8.2E-39 T 01-11-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 AFULGI_00025610 194cc61e9060df924dc9b9ce57292d59 154 Gene3D G3DSA:3.10.129.10 15 152 2.1E-43 T 01-11-2018 AFULGI_00010990 2b6b4778b21977f612adbf27e7c538d7 366 PRINTS PR00164 ABC-2 type transport system membrane protein signature 246 270 4.1E-7 T 01-11-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AFULGI_00010990 2b6b4778b21977f612adbf27e7c538d7 366 PRINTS PR00164 ABC-2 type transport system membrane protein signature 303 322 4.1E-7 T 01-11-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AFULGI_00010990 2b6b4778b21977f612adbf27e7c538d7 366 PRINTS PR00164 ABC-2 type transport system membrane protein signature 167 189 4.1E-7 T 01-11-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AFULGI_00010990 2b6b4778b21977f612adbf27e7c538d7 366 PRINTS PR00164 ABC-2 type transport system membrane protein signature 283 302 4.1E-7 T 01-11-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AFULGI_00010990 2b6b4778b21977f612adbf27e7c538d7 366 Pfam PF12698 ABC-2 family transporter protein 21 353 2.5E-42 T 01-11-2018 AFULGI_00012610 bbc4083c7f9242ec0620b211508365d8 76 Pfam PF00137 ATP synthase subunit C 14 72 8.7E-14 T 01-11-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 AFULGI_00012610 bbc4083c7f9242ec0620b211508365d8 76 Gene3D G3DSA:1.20.120.610 2 75 3.7E-15 T 01-11-2018 AFULGI_00012610 bbc4083c7f9242ec0620b211508365d8 76 SUPERFAMILY SSF81333 6 75 5.89E-14 T 01-11-2018 IPR035921 F/V-ATP synthase subunit C superfamily AFULGI_00013460 6baa18e2a125412c2964da0de4de5139 228 Pfam PF04474 Protein of unknown function (DUF554) 3 220 1.3E-76 T 01-11-2018 IPR007563 Protein of unknown function DUF554 AFULGI_00014070 a44c17416a7404ee856370eeea60d16d 174 Gene3D G3DSA:2.60.40.790 80 163 3.2E-24 T 01-11-2018 IPR008978 HSP20-like chaperone AFULGI_00014070 a44c17416a7404ee856370eeea60d16d 174 Pfam PF00011 Hsp20/alpha crystallin family 89 173 1.4E-11 T 01-11-2018 IPR002068 Alpha crystallin/Hsp20 domain AFULGI_00014070 a44c17416a7404ee856370eeea60d16d 174 SUPERFAMILY SSF49764 83 174 1.83E-23 T 01-11-2018 IPR008978 HSP20-like chaperone AFULGI_00017280 6c36949a06930d44501d4d8470a4100f 177 Gene3D G3DSA:3.10.180.10 48 175 1.1E-37 T 01-11-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFULGI_00017280 6c36949a06930d44501d4d8470a4100f 177 SUPERFAMILY SSF54593 49 172 1.88E-24 T 01-11-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFULGI_00017280 6c36949a06930d44501d4d8470a4100f 177 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 50 170 1.5E-18 T 01-11-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain AFULGI_00025280 a95ae51b2d14c579f4602124471ec5e1 329 Pfam PF04015 Domain of unknown function (DUF362) 71 271 2.1E-39 T 01-11-2018 IPR007160 Domain of unknown function DUF362 AFULGI_00026050 db0ba77e90062bbf4c141238d47b48f5 56 SUPERFAMILY SSF81593 2 50 2.51E-7 T 01-11-2018 AFULGI_00026050 db0ba77e90062bbf4c141238d47b48f5 56 Pfam PF05168 HEPN domain 2 48 1.4E-5 T 01-11-2018 IPR007842 HEPN domain AFULGI_00026050 db0ba77e90062bbf4c141238d47b48f5 56 Gene3D G3DSA:1.20.120.330 1 52 5.1E-7 T 01-11-2018 AFULGI_00019690 091c02e5ec2f74885bb9b5000eaa1323 63 ProDom PD054524 AF1718 1 58 3.0E-26 T 01-11-2018 IPR020073 Uncharacterised protein family AF1718 AFULGI_00019690 091c02e5ec2f74885bb9b5000eaa1323 63 Pfam PF17341 Family of unknown function (DUF5371) 1 63 5.4E-33 T 01-11-2018 IPR020073 Uncharacterised protein family AF1718 AFULGI_00009370 71fae3ad1b1e0fd67a12e5c7f580dfae 317 Gene3D G3DSA:3.30.70.3130 10 106 2.2E-15 T 01-11-2018 AFULGI_00009370 71fae3ad1b1e0fd67a12e5c7f580dfae 317 Pfam PF01189 16S rRNA methyltransferase RsmB/F 112 315 7.2E-50 T 01-11-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 AFULGI_00009370 71fae3ad1b1e0fd67a12e5c7f580dfae 317 Pfam PF17125 N-terminal domain of 16S rRNA methyltransferase RsmF 28 107 5.7E-17 T 01-11-2018 IPR031341 Ribosomal RNA small subunit methyltransferase F, N-terminal Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 AFULGI_00009370 71fae3ad1b1e0fd67a12e5c7f580dfae 317 SUPERFAMILY SSF53335 33 316 1.7E-60 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFULGI_00009370 71fae3ad1b1e0fd67a12e5c7f580dfae 317 Gene3D G3DSA:3.40.50.150 110 317 1.2E-70 T 01-11-2018 AFULGI_00009370 71fae3ad1b1e0fd67a12e5c7f580dfae 317 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 93 107 4.6E-25 T 01-11-2018 IPR023267 RNA (C5-cytosine) methyltransferase AFULGI_00009370 71fae3ad1b1e0fd67a12e5c7f580dfae 317 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 188 200 4.6E-25 T 01-11-2018 IPR023267 RNA (C5-cytosine) methyltransferase AFULGI_00009370 71fae3ad1b1e0fd67a12e5c7f580dfae 317 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 122 132 4.6E-25 T 01-11-2018 IPR023267 RNA (C5-cytosine) methyltransferase AFULGI_00009370 71fae3ad1b1e0fd67a12e5c7f580dfae 317 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 238 254 4.6E-25 T 01-11-2018 IPR023267 RNA (C5-cytosine) methyltransferase AFULGI_00009370 71fae3ad1b1e0fd67a12e5c7f580dfae 317 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 299 316 4.6E-25 T 01-11-2018 IPR023267 RNA (C5-cytosine) methyltransferase AFULGI_00009370 71fae3ad1b1e0fd67a12e5c7f580dfae 317 TIGRFAM TIGR00446 nop2p: NOL1/NOP2/sun family putative RNA methylase 50 316 1.7E-120 T 01-11-2018 IPR011023 Nop2p GO:0003723|GO:0006364|GO:0008757 Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 AFULGI_00006220 ebe93ed5e37b2e7402371d217302adbc 187 TIGRFAM TIGR00372 cas4: CRISPR-associated protein Cas4 14 185 2.2E-30 T 01-11-2018 IPR013343 CRISPR-associated protein Cas4 AFULGI_00006220 ebe93ed5e37b2e7402371d217302adbc 187 Gene3D G3DSA:3.90.320.10 7 187 7.8E-13 T 01-11-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal AFULGI_00006220 ebe93ed5e37b2e7402371d217302adbc 187 Pfam PF01930 Domain of unknown function DUF83 15 184 1.1E-14 T 01-11-2018 IPR022765 Dna2/Cas4, domain of unknown function DUF83 AFULGI_00016150 46ae86ff7f9621181edd89ca638371c1 77 SUPERFAMILY SSF54786 5 74 7.85E-15 T 01-11-2018 AFULGI_00016150 46ae86ff7f9621181edd89ca638371c1 77 Gene3D G3DSA:3.30.920.30 5 74 8.2E-17 T 01-11-2018 IPR038570 HicA superfamily AFULGI_00016150 46ae86ff7f9621181edd89ca638371c1 77 Pfam PF07927 HicA toxin of bacterial toxin-antitoxin, 10 67 6.1E-17 T 01-11-2018 IPR012933 HicA mRNA interferase family GO:0003729 AFULGI_00022310 0da5213b270d9692ca5c2139138a9424 138 Pfam PF00011 Hsp20/alpha crystallin family 39 137 2.6E-23 T 01-11-2018 IPR002068 Alpha crystallin/Hsp20 domain AFULGI_00022310 0da5213b270d9692ca5c2139138a9424 138 Gene3D G3DSA:2.60.40.790 1 138 4.3E-38 T 01-11-2018 IPR008978 HSP20-like chaperone AFULGI_00022310 0da5213b270d9692ca5c2139138a9424 138 SUPERFAMILY SSF49764 6 133 1.3E-36 T 01-11-2018 IPR008978 HSP20-like chaperone AFULGI_00002120 c12317ed7134b22e3875078390b27903 172 Pfam PF00881 Nitroreductase family 65 150 3.9E-19 T 01-11-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 AFULGI_00002120 c12317ed7134b22e3875078390b27903 172 Gene3D G3DSA:3.40.109.10 3 172 1.2E-60 T 01-11-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 AFULGI_00002120 c12317ed7134b22e3875078390b27903 172 SUPERFAMILY SSF55469 1 172 1.31E-58 T 01-11-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 AFULGI_00006450 51c19c28cb06f811b9762fc220a562e7 60 SUPERFAMILY SSF47598 4 47 1.78E-9 T 01-11-2018 IPR010985 Ribbon-helix-helix GO:0006355 AFULGI_00006450 51c19c28cb06f811b9762fc220a562e7 60 Gene3D G3DSA:1.10.8.1250 13 57 6.5E-5 T 01-11-2018 IPR038296 Antitoxin ParD superfamily AFULGI_00006450 51c19c28cb06f811b9762fc220a562e7 60 Pfam PF01402 Ribbon-helix-helix protein, copG family 7 45 8.9E-8 T 01-11-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 AFULGI_00006310 bc5cd769ab1843a8d53367b4e970f100 354 Pfam PF03787 RAMP superfamily 7 293 1.5E-20 T 01-11-2018 IPR005537 CRISPR type III-associated RAMP protein AFULGI_00006310 bc5cd769ab1843a8d53367b4e970f100 354 TIGRFAM TIGR01899 cas_TM1807_csm5: CRISPR type III-A/MTUBE-associated RAMP protein Csm5 6 352 2.4E-53 T 01-11-2018 IPR010173 CRISPR-associated protein, TM1807 AFULGI_00008060 b171404cef2165d82fc631971f05f617 234 Gene3D G3DSA:3.30.950.10 109 225 5.8E-27 T 01-11-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 AFULGI_00008060 b171404cef2165d82fc631971f05f617 234 SUPERFAMILY SSF53790 2 233 7.98E-62 T 01-11-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 AFULGI_00008060 b171404cef2165d82fc631971f05f617 234 Gene3D G3DSA:3.40.1010.10 1 108 8.9E-32 T 01-11-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 AFULGI_00008060 b171404cef2165d82fc631971f05f617 234 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 2 202 4.3E-49 T 01-11-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 AFULGI_00015480 b92e7c7af1474faa006d060eec0692ce 199 Pfam PF13886 Domain of unknown function (DUF4203) 18 187 3.7E-14 T 01-11-2018 IPR025256 Domain of unknown function DUF4203 AFULGI_00010680 a30b9419869a84e39778dcf3215e5c97 109 PRINTS PR00340 P-II protein signature 52 75 3.0E-39 T 01-11-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AFULGI_00010680 a30b9419869a84e39778dcf3215e5c97 109 PRINTS PR00340 P-II protein signature 2 17 3.0E-39 T 01-11-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AFULGI_00010680 a30b9419869a84e39778dcf3215e5c97 109 PRINTS PR00340 P-II protein signature 23 41 3.0E-39 T 01-11-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AFULGI_00010680 a30b9419869a84e39778dcf3215e5c97 109 PRINTS PR00340 P-II protein signature 83 103 3.0E-39 T 01-11-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AFULGI_00010680 a30b9419869a84e39778dcf3215e5c97 109 Gene3D G3DSA:3.30.70.120 1 109 1.5E-45 T 01-11-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal AFULGI_00010680 a30b9419869a84e39778dcf3215e5c97 109 SUPERFAMILY SSF54913 1 107 1.21E-39 T 01-11-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta AFULGI_00010680 a30b9419869a84e39778dcf3215e5c97 109 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 4.6E-38 T 01-11-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AFULGI_00010680 a30b9419869a84e39778dcf3215e5c97 109 SMART SM00938 4 105 7.4E-56 T 01-11-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AFULGI_00010680 a30b9419869a84e39778dcf3215e5c97 109 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 01-11-2018 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 AFULGI_00002030 cbfb645c3049fa41618e32209c77fc9f 377 Pfam PF00999 Sodium/hydrogen exchanger family 11 365 5.4E-56 T 01-11-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 AFULGI_00002030 cbfb645c3049fa41618e32209c77fc9f 377 Gene3D G3DSA:1.20.1530.20 3 373 2.6E-56 T 01-11-2018 IPR038770 Sodium/solute symporter superfamily AFULGI_00008300 1263eb495f35908ad7a4c7c3aaef9183 532 Gene3D G3DSA:3.40.920.10 1 164 5.1E-16 T 01-11-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 AFULGI_00008300 1263eb495f35908ad7a4c7c3aaef9183 532 SUPERFAMILY SSF53323 2 156 3.27E-18 T 01-11-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 AFULGI_00008300 1263eb495f35908ad7a4c7c3aaef9183 532 TIGRFAM TIGR03710 OAFO_sf: 2-oxoacid:acceptor oxidoreductase, alpha subunit 2 526 1.1E-151 T 01-11-2018 IPR022367 2-oxoacid:acceptor oxidoreductase, alpha subunit KEGG: 00020+1.2.7.3|KEGG: 00720+1.2.7.3|MetaCyc: PWY-5392|MetaCyc: PWY-6969 AFULGI_00008300 1263eb495f35908ad7a4c7c3aaef9183 532 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 190 417 2.0E-57 T 01-11-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 AFULGI_00008300 1263eb495f35908ad7a4c7c3aaef9183 532 SUPERFAMILY SSF52518 178 422 6.87E-49 T 01-11-2018 IPR029061 Thiamin diphosphate-binding fold AFULGI_00008300 1263eb495f35908ad7a4c7c3aaef9183 532 Gene3D G3DSA:3.40.50.970 167 360 1.9E-57 T 01-11-2018 AFULGI_00008300 1263eb495f35908ad7a4c7c3aaef9183 532 SUPERFAMILY SSF52922 435 529 5.38E-8 T 01-11-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 AFULGI_00008300 1263eb495f35908ad7a4c7c3aaef9183 532 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 9 160 4.5E-21 T 01-11-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 AFULGI_00008300 1263eb495f35908ad7a4c7c3aaef9183 532 Gene3D G3DSA:3.40.50.920 435 530 1.2E-11 T 01-11-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 AFULGI_00017560 6b801bb66e7e3fec7260e7af7b37197d 198 Gene3D G3DSA:2.40.40.20 117 198 1.5E-6 T 01-11-2018 AFULGI_00017560 6b801bb66e7e3fec7260e7af7b37197d 198 Pfam PF02359 Cell division protein 48 (CDC48), N-terminal domain 132 195 3.4E-6 T 01-11-2018 IPR003338 CDC48, N-terminal subdomain AFULGI_00017560 6b801bb66e7e3fec7260e7af7b37197d 198 SUPERFAMILY SSF50692 122 196 2.49E-6 T 01-11-2018 IPR009010 Aspartate decarboxylase-like domain superfamily AFULGI_00015590 ef4a62a316a16edc0122541ec3624041 473 Pfam PF07728 AAA domain (dynein-related subfamily) 143 258 1.2E-8 T 01-11-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 AFULGI_00015590 ef4a62a316a16edc0122541ec3624041 473 SUPERFAMILY SSF52540 58 375 2.1E-27 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00015590 ef4a62a316a16edc0122541ec3624041 473 Pfam PF01078 Magnesium chelatase, subunit ChlI 59 105 5.8E-5 T 01-11-2018 IPR000523 Magnesium chelatase ChlI domain AFULGI_00015590 ef4a62a316a16edc0122541ec3624041 473 Gene3D G3DSA:3.40.50.300 55 263 6.5E-33 T 01-11-2018 AFULGI_00026730 09bc36b72b454f1962978b04a5fdf2ca 234 Pfam PF13484 4Fe-4S double cluster binding domain 161 225 3.8E-8 T 01-11-2018 AFULGI_00026730 09bc36b72b454f1962978b04a5fdf2ca 234 SUPERFAMILY SSF54862 156 225 8.97E-8 T 01-11-2018 AFULGI_00012210 ba1d842918c7ed54d34396087056454a 159 Pfam PF01575 MaoC like domain 32 143 1.2E-30 T 01-11-2018 IPR002539 MaoC-like dehydratase domain AFULGI_00012210 ba1d842918c7ed54d34396087056454a 159 Gene3D G3DSA:3.10.129.10 1 159 2.3E-53 T 01-11-2018 AFULGI_00012210 ba1d842918c7ed54d34396087056454a 159 SUPERFAMILY SSF54637 9 158 6.77E-34 T 01-11-2018 IPR029069 HotDog domain superfamily AFULGI_00012210 ba1d842918c7ed54d34396087056454a 159 PRINTS PR01483 Fatty acid synthase signature 50 72 2.6E-5 T 01-11-2018 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 AFULGI_00012210 ba1d842918c7ed54d34396087056454a 159 PRINTS PR01483 Fatty acid synthase signature 72 93 2.6E-5 T 01-11-2018 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 AFULGI_00015800 1613bfc68f8dd582d5d36156f78461e4 73 Pfam PF02697 Putative antitoxin 4 61 1.3E-15 T 01-11-2018 IPR003847 Putative antitoxin AFULGI_00015800 1613bfc68f8dd582d5d36156f78461e4 73 ProDom PD188822 UPF0330 AF1997 ST1125.1 AF1689 AF1478 C1_0043 PYRAB04040 PF1222 MM2475 MA1514 4 56 5.0E-6 T 01-11-2018 IPR003847 Putative antitoxin AFULGI_00003550 375b47f6adffe69c2aacb93903b9084c 238 Pfam PF06745 KaiC 6 222 1.6E-24 T 01-11-2018 IPR014774 KaiC-like domain AFULGI_00003550 375b47f6adffe69c2aacb93903b9084c 238 SUPERFAMILY SSF52540 6 223 2.38E-25 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00003550 375b47f6adffe69c2aacb93903b9084c 238 Gene3D G3DSA:3.40.50.300 3 224 2.0E-34 T 01-11-2018 AFULGI_00007250 2512c9397a35f3ce2623e776d2de6a81 275 ProSitePatterns PS01053 Arginase family signature. 199 220 - T 01-11-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 AFULGI_00007250 2512c9397a35f3ce2623e776d2de6a81 275 Pfam PF00491 Arginase family 19 264 3.5E-58 T 01-11-2018 IPR006035 Ureohydrolase GO:0046872 AFULGI_00007250 2512c9397a35f3ce2623e776d2de6a81 275 SUPERFAMILY SSF52768 3 268 7.92E-67 T 01-11-2018 IPR023696 Ureohydrolase domain superfamily AFULGI_00007250 2512c9397a35f3ce2623e776d2de6a81 275 PIRSF PIRSF036979 1 272 3.0E-88 T 01-11-2018 IPR006035 Ureohydrolase GO:0046872 AFULGI_00007250 2512c9397a35f3ce2623e776d2de6a81 275 Gene3D G3DSA:3.40.800.10 2 272 5.4E-73 T 01-11-2018 AFULGI_00007250 2512c9397a35f3ce2623e776d2de6a81 275 TIGRFAM TIGR01230 agmatinase: agmatinase 5 266 2.9E-111 T 01-11-2018 IPR005925 Agmatinase-related KEGG: 00330+3.5.3.11|MetaCyc: PWY-40|MetaCyc: PWY-6305|Reactome: R-HSA-351143 AFULGI_00024430 4d587fc87b1bbbfebf97b71ea9556e7b 340 Pfam PF00882 Zinc dependent phospholipase C 44 202 4.9E-9 T 01-11-2018 IPR029002 Phospholipase C/D Reactome: R-HSA-163125 AFULGI_00013430 1fb99d64c06b7f5571581e627dd0ed37 338 Gene3D G3DSA:1.20.1530.20 1 338 8.5E-40 T 01-11-2018 IPR038770 Sodium/solute symporter superfamily AFULGI_00013430 1fb99d64c06b7f5571581e627dd0ed37 338 Pfam PF00999 Sodium/hydrogen exchanger family 5 335 2.2E-33 T 01-11-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 AFULGI_00026450 4bc88d495f57774fa464602e48fd09ed 365 SUPERFAMILY SSF101960 43 359 1.26E-78 T 01-11-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily AFULGI_00026450 4bc88d495f57774fa464602e48fd09ed 365 Pfam PF01458 Uncharacterized protein family (UPF0051) 116 337 9.3E-54 T 01-11-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 AFULGI_00023720 46a30dc83e50969e0341d69bfff47ef7 379 Gene3D G3DSA:3.20.20.70 1 325 1.6E-20 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFULGI_00023720 46a30dc83e50969e0341d69bfff47ef7 379 Pfam PF04055 Radical SAM superfamily 8 127 4.0E-11 T 01-11-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFULGI_00023720 46a30dc83e50969e0341d69bfff47ef7 379 SUPERFAMILY SSF102114 5 347 1.04E-23 T 01-11-2018 AFULGI_00009540 da1203e67e6ffaa81ee9e5801d09ea36 108 Gene3D G3DSA:3.30.110.70 5 108 3.0E-34 T 01-11-2018 AFULGI_00009540 da1203e67e6ffaa81ee9e5801d09ea36 108 Hamap MF_00338 UPF0145 protein YbjQ [ybjQ]. 5 107 25.937 T 01-11-2018 IPR002765 Uncharacterised protein family UPF0145 AFULGI_00009540 da1203e67e6ffaa81ee9e5801d09ea36 108 Pfam PF01906 Putative heavy-metal-binding 5 106 2.0E-39 T 01-11-2018 IPR002765 Uncharacterised protein family UPF0145 AFULGI_00009540 da1203e67e6ffaa81ee9e5801d09ea36 108 SUPERFAMILY SSF117782 5 107 1.44E-37 T 01-11-2018 IPR035439 UPF0145 domain superfamily AFULGI_00026680 22233cd69e0bf1e11020b56ec2014c00 92 Pfam PF01893 Uncharacterised protein family UPF0058 7 87 9.0E-27 T 01-11-2018 IPR002753 Uncharacterised protein family UPF0058 AFULGI_00026680 22233cd69e0bf1e11020b56ec2014c00 92 Gene3D G3DSA:1.20.1270.110 6 77 9.8E-21 T 01-11-2018 IPR036519 Uncharacterised UPF0058 superfamily AFULGI_00026680 22233cd69e0bf1e11020b56ec2014c00 92 SUPERFAMILY SSF140371 6 87 2.09E-25 T 01-11-2018 IPR036519 Uncharacterised UPF0058 superfamily AFULGI_00008960 56008ccb0df9b6296944bd97d87df2c7 123 Pfam PF02589 LUD domain 85 120 4.6E-5 T 01-11-2018 IPR003741 LUD domain AFULGI_00008960 56008ccb0df9b6296944bd97d87df2c7 123 Gene3D G3DSA:3.40.50.10420 3 120 1.1E-12 T 01-11-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily AFULGI_00008960 56008ccb0df9b6296944bd97d87df2c7 123 SUPERFAMILY SSF100950 35 120 6.7E-11 T 01-11-2018 IPR037171 NagB/RpiA transferase-like AFULGI_00005120 4698d19a445ae192d0ee2d8909150e9e 555 Pfam PF13183 4Fe-4S dicluster domain 89 174 1.7E-9 T 01-11-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFULGI_00005120 4698d19a445ae192d0ee2d8909150e9e 555 SUPERFAMILY SSF46548 80 189 1.1E-15 T 01-11-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 AFULGI_00005120 4698d19a445ae192d0ee2d8909150e9e 555 Pfam PF02754 Cysteine-rich domain 412 498 2.8E-5 T 01-11-2018 IPR004017 Cysteine-rich domain AFULGI_00005120 4698d19a445ae192d0ee2d8909150e9e 555 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 160 171 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFULGI_00017720 a104bbbfd6e1c7e8a0ef6996d39804c7 195 Pfam PF03358 NADPH-dependent FMN reductase 2 152 9.7E-35 T 01-11-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 AFULGI_00017720 a104bbbfd6e1c7e8a0ef6996d39804c7 195 SUPERFAMILY SSF52218 2 192 5.28E-39 T 01-11-2018 IPR029039 Flavoprotein-like superfamily AFULGI_00017720 a104bbbfd6e1c7e8a0ef6996d39804c7 195 Gene3D G3DSA:3.40.50.360 2 194 3.1E-37 T 01-11-2018 IPR029039 Flavoprotein-like superfamily AFULGI_00026190 2ed09918bd47a7199fb997184121a6ee 194 Pfam PF00827 Ribosomal L15 3 188 2.4E-81 T 01-11-2018 IPR000439 Ribosomal protein L15e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00026190 2ed09918bd47a7199fb997184121a6ee 194 Gene3D G3DSA:3.40.1120.10 1 192 4.3E-81 T 01-11-2018 IPR024794 Ribosomal protein L15e core domain superfamily GO:0003735|GO:0005840 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00026190 2ed09918bd47a7199fb997184121a6ee 194 SUPERFAMILY SSF54189 2 193 2.49E-80 T 01-11-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFULGI_00026190 2ed09918bd47a7199fb997184121a6ee 194 SMART SM01384 3 190 4.6E-117 T 01-11-2018 IPR000439 Ribosomal protein L15e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00026190 2ed09918bd47a7199fb997184121a6ee 194 ProSitePatterns PS01194 Ribosomal protein L15e signature. 47 70 - T 01-11-2018 IPR020925 Ribosomal protein L15e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00026190 2ed09918bd47a7199fb997184121a6ee 194 Hamap MF_00256 50S ribosomal protein L15e [rpl15e]. 2 192 42.938 T 01-11-2018 IPR020926 Ribosomal protein L15e, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFULGI_00007550 aa14bcd66589e2dac2c5634e5ebf32ab 238 Pfam PF12146 Serine aminopeptidase, S33 36 119 4.6E-10 T 01-11-2018 IPR022742 Serine aminopeptidase, S33 AFULGI_00007550 aa14bcd66589e2dac2c5634e5ebf32ab 238 Gene3D G3DSA:3.40.50.1820 9 235 4.5E-36 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold AFULGI_00007550 aa14bcd66589e2dac2c5634e5ebf32ab 238 SUPERFAMILY SSF53474 19 230 4.5E-34 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold AFULGI_00000470 ad183d6317a4ff4ca8e6c4f441dcb7b7 338 Pfam PF02163 Peptidase family M50 214 277 2.2E-8 T 01-11-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 AFULGI_00020990 1aba22053557e7ec735bf51af35946dc 295 Pfam PF13190 PDGLE domain 184 288 2.9E-8 T 01-11-2018 IPR025937 PDGLE domain AFULGI_00020990 1aba22053557e7ec735bf51af35946dc 295 Gene3D G3DSA:1.10.1760.20 1 198 3.3E-66 T 01-11-2018 AFULGI_00020990 1aba22053557e7ec735bf51af35946dc 295 Pfam PF01891 Cobalt uptake substrate-specific transmembrane region 2 198 5.1E-64 T 01-11-2018 IPR002751 Metal transport protein CbiM/NikMN GO:0000041|GO:0016021 AFULGI_00005300 f158b26efe8bd43da279b64f8d7312b4 154 Pfam PF00583 Acetyltransferase (GNAT) family 13 136 1.2E-22 T 01-11-2018 IPR000182 GNAT domain AFULGI_00005300 f158b26efe8bd43da279b64f8d7312b4 154 Gene3D G3DSA:3.40.630.30 1 152 5.8E-45 T 01-11-2018 AFULGI_00005300 f158b26efe8bd43da279b64f8d7312b4 154 SUPERFAMILY SSF55729 2 142 2.03E-34 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase AFULGI_00014740 db27d9c4f0eb20a67427ba303bd65545 87 Pfam PF09868 Uncharacterized protein conserved in archaea (DUF2095) 25 82 4.5E-8 T 01-11-2018 IPR018662 Protein of unknown function DUF2095 AFULGI_00019520 013299fc79e55e1cf466eac2b6e45ff9 208 Pfam PF01810 LysE type translocator 15 198 5.0E-43 T 01-11-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 AFULGI_00006570 77c2690cc0c77f4d216d588d9bfe3592 528 SUPERFAMILY SSF53448 1 247 2.19E-47 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFULGI_00006570 77c2690cc0c77f4d216d588d9bfe3592 528 Gene3D G3DSA:3.90.550.10 1 244 3.0E-52 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFULGI_00006570 77c2690cc0c77f4d216d588d9bfe3592 528 Pfam PF00535 Glycosyl transferase family 2 4 168 9.6E-34 T 01-11-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 AFULGI_00006570 77c2690cc0c77f4d216d588d9bfe3592 528 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 241 511 3.7E-42 T 01-11-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD AFULGI_00006570 77c2690cc0c77f4d216d588d9bfe3592 528 TIGRFAM TIGR00374 TIGR00374: TIGR00374 family protein 406 521 1.3E-13 T 01-11-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD AFULGI_00006570 77c2690cc0c77f4d216d588d9bfe3592 528 TIGRFAM TIGR00374 TIGR00374: TIGR00374 family protein 241 384 4.8E-12 T 01-11-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD AFULGI_00006730 6c91a77984aa55463752564c3b6c9f15 150 Pfam PF11848 Domain of unknown function (DUF3368) 102 147 1.9E-17 T 01-11-2018 IPR021799 Protein of unknown function DUF3368 AFULGI_00026980 3727daed7e3d24caa251c3f62fad966b 132 Gene3D G3DSA:1.20.120.580 2 131 1.1E-13 T 01-11-2018 IPR037038 Bsu32300-like superfamily AFULGI_00026980 3727daed7e3d24caa251c3f62fad966b 132 Pfam PF01934 Protein of unknown function DUF86 5 122 1.8E-23 T 01-11-2018 IPR008201 Protein of unknown function DUF86 AFULGI_00011920 03ab0a68a4201bcc3d12035de9ac5b28 141 Pfam PF07790 Archaeal Type IV pilin, N-terminal 9 85 8.0E-27 T 01-11-2018 IPR012859 Archaeal Type IV pilin, N-terminal AFULGI_00011920 03ab0a68a4201bcc3d12035de9ac5b28 141 TIGRFAM TIGR02537 arch_flag_Nterm: archaeal flagellin N-terminal-like domain 9 31 1.3E-7 T 01-11-2018 IPR013373 Flagellin/pilin, N-terminal AFULGI_00007410 de3616661f3e5c0d32370752adec247c 379 Gene3D G3DSA:1.10.1060.10 14 98 1.1E-5 T 01-11-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 AFULGI_00007410 de3616661f3e5c0d32370752adec247c 379 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 66 77 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFULGI_00007410 de3616661f3e5c0d32370752adec247c 379 SUPERFAMILY SSF103501 216 372 4.71E-22 T 01-11-2018 IPR036197 NarG-like superfamily AFULGI_00007410 de3616661f3e5c0d32370752adec247c 379 SUPERFAMILY SSF46548 19 95 5.58E-15 T 01-11-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 AFULGI_00007410 de3616661f3e5c0d32370752adec247c 379 Pfam PF13534 4Fe-4S dicluster domain 21 79 4.7E-7 T 01-11-2018 AFULGI_00013800 ea04e4c2318c99f82eb11fe1cdeca985 331 Gene3D G3DSA:3.30.200.20 1 100 7.6E-12 T 01-11-2018 AFULGI_00013800 ea04e4c2318c99f82eb11fe1cdeca985 331 Gene3D G3DSA:3.30.470.20 115 264 2.7E-20 T 01-11-2018 AFULGI_00013800 ea04e4c2318c99f82eb11fe1cdeca985 331 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 1 310 22.369 T 01-11-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 AFULGI_00013800 ea04e4c2318c99f82eb11fe1cdeca985 331 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 2 316 4.7E-110 T 01-11-2018 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 AFULGI_00013800 ea04e4c2318c99f82eb11fe1cdeca985 331 SUPERFAMILY SSF56104 2 313 2.16E-49 T 01-11-2018 AFULGI_00013800 ea04e4c2318c99f82eb11fe1cdeca985 331 Pfam PF01259 SAICAR synthetase 22 269 1.7E-24 T 01-11-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 AFULGI_00005480 e8e4bf42d83279b5b035500000e709f7 233 Pfam PF03029 Conserved hypothetical ATP binding protein 5 227 8.7E-57 T 01-11-2018 IPR004130 GPN-loop GTPase AFULGI_00005480 e8e4bf42d83279b5b035500000e709f7 233 SUPERFAMILY SSF52540 3 225 9.75E-28 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00005480 e8e4bf42d83279b5b035500000e709f7 233 Gene3D G3DSA:3.40.50.300 1 229 1.6E-48 T 01-11-2018 AFULGI_00017260 40eda2519068c99c0477c11c1914a215 448 ProSitePatterns PS00455 Putative AMP-binding domain signature. 75 86 - T 01-11-2018 IPR020845 AMP-binding, conserved site AFULGI_00009130 6bf915c90f0ad0134232ca4c7e0f08a2 461 Gene3D G3DSA:3.40.50.2300 30 175 1.0E-22 T 01-11-2018 AFULGI_00009130 6bf915c90f0ad0134232ca4c7e0f08a2 461 SUPERFAMILY SSF53822 43 400 1.5E-52 T 01-11-2018 IPR028082 Periplasmic binding protein-like I AFULGI_00009130 6bf915c90f0ad0134232ca4c7e0f08a2 461 Gene3D G3DSA:3.40.50.2300 307 403 1.2E-7 T 01-11-2018 AFULGI_00009130 6bf915c90f0ad0134232ca4c7e0f08a2 461 Pfam PF13458 Periplasmic binding protein 44 268 4.4E-36 T 01-11-2018 IPR028081 Leucine-binding protein domain AFULGI_00009130 6bf915c90f0ad0134232ca4c7e0f08a2 461 Gene3D G3DSA:3.40.50.2300 176 286 2.3E-20 T 01-11-2018 AFULGI_00017040 a71a469b50a46dbc6a286ed8cd56281e 212 SUPERFAMILY SSF53098 75 209 8.16E-8 T 01-11-2018 IPR012337 Ribonuclease H-like superfamily AFULGI_00017040 a71a469b50a46dbc6a286ed8cd56281e 212 Pfam PF13610 DDE domain 82 211 1.6E-14 T 01-11-2018 IPR032874 DDE domain AFULGI_00007170 03ae48fc028762abf6252ce7bf17f46e 676 TIGRFAM TIGR02123 TRAP_fused: TRAP transporter, 4TM/12TM fusion protein 26 671 9.3E-241 T 01-11-2018 IPR011853 TRAP C4-dicarboxylate transport system permease, fused DctM-DctQ AFULGI_00007170 03ae48fc028762abf6252ce7bf17f46e 676 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 125 596 3.2E-123 T 01-11-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit AFULGI_00009040 fe43a54fa29ce9f0c43fad556d708952 89 Gene3D G3DSA:3.30.70.100 1 89 5.9E-30 T 01-11-2018 AFULGI_00009040 fe43a54fa29ce9f0c43fad556d708952 89 ProSitePatterns PS00151 Acylphosphatase signature 2. 32 48 - T 01-11-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 AFULGI_00009040 fe43a54fa29ce9f0c43fad556d708952 89 ProSitePatterns PS00150 Acylphosphatase signature 1. 8 18 - T 01-11-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 AFULGI_00009040 fe43a54fa29ce9f0c43fad556d708952 89 Pfam PF00708 Acylphosphatase 5 86 3.2E-27 T 01-11-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 AFULGI_00009040 fe43a54fa29ce9f0c43fad556d708952 89 SUPERFAMILY SSF54975 1 88 1.09E-28 T 01-11-2018 IPR036046 Acylphosphatase-like domain superfamily KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 AFULGI_00014130 036e9a2fc8cbbe4317acc31971425c2a 261 PRINTS PR00164 ABC-2 type transport system membrane protein signature 53 75 2.8E-6 T 01-11-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AFULGI_00014130 036e9a2fc8cbbe4317acc31971425c2a 261 PRINTS PR00164 ABC-2 type transport system membrane protein signature 173 192 2.8E-6 T 01-11-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AFULGI_00014130 036e9a2fc8cbbe4317acc31971425c2a 261 PRINTS PR00164 ABC-2 type transport system membrane protein signature 193 212 2.8E-6 T 01-11-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AFULGI_00014130 036e9a2fc8cbbe4317acc31971425c2a 261 Pfam PF01061 ABC-2 type transporter 23 213 3.1E-7 T 01-11-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 AFULGI_00022420 a1f2ef842ce21dc44ef8383b5976bbf5 261 Pfam PF00950 ABC 3 transport family 1 259 4.9E-73 T 01-11-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 AFULGI_00022420 a1f2ef842ce21dc44ef8383b5976bbf5 261 SUPERFAMILY SSF81345 3 260 3.79E-26 T 01-11-2018 IPR037294 ABC transporter, BtuC-like AFULGI_00016390 f10ab3eb60b1a97cde3b45638a2ffddb 147 Pfam PF01850 PIN domain 53 120 4.1E-7 T 01-11-2018 IPR002716 PIN domain AFULGI_00016390 f10ab3eb60b1a97cde3b45638a2ffddb 147 SUPERFAMILY SSF88723 2 125 1.93E-11 T 01-11-2018 IPR029060 PIN-like domain superfamily AFULGI_00015310 b5a211284d6f28a1e8461aa2f7f7c39d 372 Gene3D G3DSA:3.90.1150.10 7 353 6.4E-128 T 01-11-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFULGI_00015310 b5a211284d6f28a1e8461aa2f7f7c39d 372 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 174 194 - T 01-11-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site AFULGI_00015310 b5a211284d6f28a1e8461aa2f7f7c39d 372 Gene3D G3DSA:3.40.640.10 12 248 6.4E-128 T 01-11-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFULGI_00015310 b5a211284d6f28a1e8461aa2f7f7c39d 372 SUPERFAMILY SSF53383 2 351 4.68E-99 T 01-11-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFULGI_00015310 b5a211284d6f28a1e8461aa2f7f7c39d 372 PIRSF PIRSF000524 1 367 5.9E-128 T 01-11-2018 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661|Reactome: R-HSA-9033241 AFULGI_00015310 b5a211284d6f28a1e8461aa2f7f7c39d 372 Pfam PF00266 Aminotransferase class-V 3 341 2.2E-37 T 01-11-2018 IPR000192 Aminotransferase class V domain AFULGI_00026310 b71ca287c54a1b1c6aa9428573a6d90d 92 Pfam PF14556 AF2331-like 1 90 8.4E-46 T 01-11-2018 IPR028986 AF2331-like domain AFULGI_00026310 b71ca287c54a1b1c6aa9428573a6d90d 92 Gene3D G3DSA:3.30.1970.10 1 92 9.1E-50 T 01-11-2018 IPR036842 AF2331-like superfamily AFULGI_00026310 b71ca287c54a1b1c6aa9428573a6d90d 92 SUPERFAMILY SSF143995 1 92 6.93E-58 T 01-11-2018 IPR036842 AF2331-like superfamily AFULGI_00016510 da5227e906d2a51eef904abbc1625e3d 186 Pfam PF01944 Stage II sporulation protein M 11 172 3.8E-29 T 01-11-2018 IPR002798 Stage II sporulation protein M-like AFULGI_00024640 9d14e85895f849bb0a24f6f5ec919b34 392 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 71 97 6.4E-22 T 01-11-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 AFULGI_00024640 9d14e85895f849bb0a24f6f5ec919b34 392 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 223 243 6.4E-22 T 01-11-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 AFULGI_00024640 9d14e85895f849bb0a24f6f5ec919b34 392 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 121 138 6.4E-22 T 01-11-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 AFULGI_00024640 9d14e85895f849bb0a24f6f5ec919b34 392 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 189 215 6.4E-22 T 01-11-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 AFULGI_00024640 9d14e85895f849bb0a24f6f5ec919b34 392 Pfam PF01578 Cytochrome C assembly protein 80 264 5.1E-28 T 01-11-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 AFULGI_00002930 03c6aa621c6d2420bfbc3179c3360f20 157 SUPERFAMILY SSF88723 3 118 2.55E-7 T 01-11-2018 IPR029060 PIN-like domain superfamily AFULGI_00002930 03c6aa621c6d2420bfbc3179c3360f20 157 TIGRFAM TIGR00305 TIGR00305: putative toxin-antitoxin system toxin component, PIN family 3 116 8.0E-48 T 01-11-2018 IPR002850 PIN family, putative toxin-antitoxin system toxin component AFULGI_00002930 03c6aa621c6d2420bfbc3179c3360f20 157 SMART SM00670 2 115 7.1E-15 T 01-11-2018 IPR002716 PIN domain AFULGI_00002930 03c6aa621c6d2420bfbc3179c3360f20 157 Pfam PF13470 PIN domain 3 111 2.9E-17 T 01-11-2018 IPR002716 PIN domain AFULGI_00025010 9d3f58f887949c590fb52b286915b8e6 316 Pfam PF08461 Ribonuclease R winged-helix domain 4 68 6.9E-24 T 01-11-2018 IPR013668 Ribonuclease R winged-helix domain AFULGI_00025010 9d3f58f887949c590fb52b286915b8e6 316 SUPERFAMILY SSF46785 4 88 2.35E-8 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00025010 9d3f58f887949c590fb52b286915b8e6 316 Gene3D G3DSA:3.30.70.1360 92 312 5.0E-48 T 01-11-2018 IPR036984 NrpR domain superfamily AFULGI_00025010 9d3f58f887949c590fb52b286915b8e6 316 Gene3D G3DSA:3.30.70.1360 160 285 5.0E-48 T 01-11-2018 IPR036984 NrpR domain superfamily AFULGI_00025010 9d3f58f887949c590fb52b286915b8e6 316 Pfam PF01995 Domain of unknown function DUF128 78 314 2.8E-62 T 01-11-2018 IPR002846 NrpR regulatory domain AFULGI_00025010 9d3f58f887949c590fb52b286915b8e6 316 Gene3D G3DSA:1.10.10.10 1 76 2.0E-10 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00012000 9718611a24d9b3994a53f0fdf62ce979 182 PIRSF PIRSF024051 1 182 2.3E-60 T 01-11-2018 IPR018036 Protein of unknown function DUF429, subgroup AFULGI_00012000 9718611a24d9b3994a53f0fdf62ce979 182 Pfam PF04250 Protein of unknown function (DUF429) 19 157 2.3E-11 T 01-11-2018 IPR007362 Protein of unknown function DUF429 AFULGI_00024600 ba52509d289259e450d9dda486009278 72 Pfam PF02381 MraZ protein, putative antitoxin-like 7 43 5.5E-5 T 01-11-2018 IPR020603 MraZ domain AFULGI_00024600 ba52509d289259e450d9dda486009278 72 SUPERFAMILY SSF89447 3 44 3.4E-9 T 01-11-2018 IPR037914 SpoVT-AbrB domain superfamily AFULGI_00024600 ba52509d289259e450d9dda486009278 72 Gene3D G3DSA:2.10.260.10 4 43 1.5E-5 T 01-11-2018 AFULGI_00024600 ba52509d289259e450d9dda486009278 72 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 6 41 1.1E-8 T 01-11-2018 IPR007159 SpoVT-AbrB domain GO:0003677 AFULGI_00024600 ba52509d289259e450d9dda486009278 72 SMART SM00966 6 46 4.5E-7 T 01-11-2018 IPR007159 SpoVT-AbrB domain GO:0003677 AFULGI_00026330 e0f42dd5d67d86bd6c58e7a3cef9086b 372 Pfam PF04412 Protein of unknown function (DUF521) 1 368 5.6E-140 T 01-11-2018 IPR007506 Aconitase X catalytic domain, putative AFULGI_00022060 faf3e2bd033adee412474044251bf210 212 Pfam PF03891 Domain of unknown function (DUF333) 21 65 2.7E-14 T 01-11-2018 IPR005590 Protein of unknown function DUF333 AFULGI_00017230 ee781ba521b3bfe98a29ad751ca8bf7d 447 Pfam PF01554 MatE 239 404 1.3E-33 T 01-11-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 AFULGI_00017230 ee781ba521b3bfe98a29ad751ca8bf7d 447 Pfam PF01554 MatE 21 180 1.9E-37 T 01-11-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 AFULGI_00017230 ee781ba521b3bfe98a29ad751ca8bf7d 447 PIRSF PIRSF006603 1 444 4.1E-83 T 01-11-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 AFULGI_00017230 ee781ba521b3bfe98a29ad751ca8bf7d 447 TIGRFAM TIGR00797 matE: MATE efflux family protein 21 413 5.6E-73 T 01-11-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 AFULGI_00003640 75dbbdb396077d9fc329a8ec039e2836 128 SUPERFAMILY SSF46785 4 67 1.11E-13 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00003640 75dbbdb396077d9fc329a8ec039e2836 128 Pfam PF01047 MarR family 6 55 1.2E-10 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFULGI_00003640 75dbbdb396077d9fc329a8ec039e2836 128 Gene3D G3DSA:1.10.10.10 1 94 1.6E-10 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00018510 22ff6239be7a7c5e3cf194e84f093058 199 SUPERFAMILY SSF51366 1 195 5.34E-40 T 01-11-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 AFULGI_00018510 22ff6239be7a7c5e3cf194e84f093058 199 Pfam PF00697 N-(5'phosphoribosyl)anthranilate (PRA) isomerase 3 192 9.1E-34 T 01-11-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 AFULGI_00018510 22ff6239be7a7c5e3cf194e84f093058 199 Gene3D G3DSA:3.20.20.70 1 198 3.1E-58 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFULGI_00018510 22ff6239be7a7c5e3cf194e84f093058 199 Hamap MF_00135 N-(5'-phosphoribosyl)anthranilate isomerase [trpF]. 1 197 31.396 T 01-11-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 AFULGI_00007580 cdd9f9091309578700e4e8116d033741 160 Pfam PF13565 Homeodomain-like domain 62 132 1.1E-15 T 01-11-2018 AFULGI_00007580 cdd9f9091309578700e4e8116d033741 160 SUPERFAMILY SSF46689 34 136 3.4E-19 T 01-11-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFULGI_00012490 b0e9e0305b965a9cdcef81a916881636 78 Pfam PF09341 Transcription factor Pcc1 19 71 1.9E-8 T 01-11-2018 IPR015419 CTAG/Pcc1 family AFULGI_00012490 b0e9e0305b965a9cdcef81a916881636 78 Gene3D G3DSA:3.30.310.50 4 74 9.1E-17 T 01-11-2018 AFULGI_00011810 e59a37d762541f241b11de09b393f127 72 SUPERFAMILY SSF88723 1 49 1.46E-8 T 01-11-2018 IPR029060 PIN-like domain superfamily AFULGI_00011810 e59a37d762541f241b11de09b393f127 72 Pfam PF01850 PIN domain 3 64 2.4E-7 T 01-11-2018 IPR002716 PIN domain AFULGI_00024510 e759ba89de757e0e0a4fee075d845708 175 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 3 153 9.3E-47 T 01-11-2018 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 AFULGI_00024510 e759ba89de757e0e0a4fee075d845708 175 SUPERFAMILY SSF56300 1 156 4.52E-33 T 01-11-2018 AFULGI_00024510 e759ba89de757e0e0a4fee075d845708 175 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 3 139 1.1E-23 T 01-11-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 AFULGI_00024510 e759ba89de757e0e0a4fee075d845708 175 Gene3D G3DSA:3.60.21.10 1 157 5.2E-36 T 01-11-2018 IPR029052 Metallo-dependent phosphatase-like AFULGI_00024700 b837e0fcb76600add4b0fdd812bd1ff4 121 Pfam PF14464 Prokaryotic homologs of the JAB domain 7 105 2.5E-11 T 01-11-2018 IPR028090 JAB domain, prokaryotic AFULGI_00024700 b837e0fcb76600add4b0fdd812bd1ff4 121 Gene3D G3DSA:3.40.140.10 1 121 4.2E-36 T 01-11-2018 AFULGI_00024700 b837e0fcb76600add4b0fdd812bd1ff4 121 SUPERFAMILY SSF102712 1 117 9.68E-32 T 01-11-2018 AFULGI_00003100 394e0ec7702839735373e960dde61f51 64 SUPERFAMILY SSF141694 1 61 7.06E-16 T 01-11-2018 AFULGI_00003100 394e0ec7702839735373e960dde61f51 64 Pfam PF01954 Protein of unknown function DUF104 1 59 7.7E-25 T 01-11-2018 IPR008203 Uncharacterised protein family UPF0165 AFULGI_00003100 394e0ec7702839735373e960dde61f51 64 Gene3D G3DSA:4.10.1150.10 1 63 8.4E-17 T 01-11-2018 IPR024069 AF2212-like domain superfamily AFULGI_00013540 5f9ed19bfe31b9aae4a0b15948dd6c2a 128 SUPERFAMILY SSF52172 9 125 6.83E-33 T 01-11-2018 IPR011006 CheY-like superfamily AFULGI_00013540 5f9ed19bfe31b9aae4a0b15948dd6c2a 128 Gene3D G3DSA:3.40.50.2300 4 128 9.9E-34 T 01-11-2018 AFULGI_00013540 5f9ed19bfe31b9aae4a0b15948dd6c2a 128 SMART SM00448 10 119 1.8E-27 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFULGI_00013540 5f9ed19bfe31b9aae4a0b15948dd6c2a 128 Pfam PF00072 Response regulator receiver domain 12 119 1.8E-24 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFULGI_00015030 59549657d8db7950af687d667db793dd 312 Pfam PF02653 Branched-chain amino acid transport system / permease component 14 292 1.6E-49 T 01-11-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 AFULGI_00003750 8442078fc0032e9527be89e588a70dea 214 Gene3D G3DSA:1.20.1440.150 1 90 4.1E-8 T 01-11-2018 AFULGI_00003750 8442078fc0032e9527be89e588a70dea 214 Gene3D G3DSA:2.40.50.140 112 213 3.1E-6 T 01-11-2018 AFULGI_00006330 a81e2dcfcf1dab1413113e9a49b85eb6 238 Pfam PF09623 CRISPR-associated protein NE0113 (Cas_NE0113) 2 201 2.1E-27 T 01-11-2018 IPR019092 CRISPR-assoc protein, NE0113/Csx13 AFULGI_00006330 a81e2dcfcf1dab1413113e9a49b85eb6 238 TIGRFAM TIGR03642 cas_csx14: CRISPR-associated protein, Csx14 family 2 119 6.9E-34 T 01-11-2018 IPR019848 CRISPR-associated protein, Csx14 AFULGI_00015130 b7c965f8432c95de90bf5c07dc1d9ef3 291 SMART SM00382 27 211 4.9E-16 T 01-11-2018 IPR003593 AAA+ ATPase domain AFULGI_00015130 b7c965f8432c95de90bf5c07dc1d9ef3 291 Gene3D G3DSA:3.40.50.300 3 244 2.3E-65 T 01-11-2018 AFULGI_00015130 b7c965f8432c95de90bf5c07dc1d9ef3 291 Pfam PF00005 ABC transporter 18 164 8.2E-32 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFULGI_00015130 b7c965f8432c95de90bf5c07dc1d9ef3 291 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFULGI_00015130 b7c965f8432c95de90bf5c07dc1d9ef3 291 SUPERFAMILY SSF52540 3 226 8.71E-60 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00002650 970e03349a0f16dd92a065947ae7a79d 143 Pfam PF07849 Protein of unknown function (DUF1641) 102 140 5.3E-16 T 01-11-2018 IPR012440 Protein of unknown function DUF1641 AFULGI_00020790 ec0362710625942aa4e98465fd256343 487 Pfam PF00361 Proton-conducting membrane transporter 138 414 4.4E-51 T 01-11-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFULGI_00020790 ec0362710625942aa4e98465fd256343 487 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 237 261 1.2E-14 T 01-11-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFULGI_00020790 ec0362710625942aa4e98465fd256343 487 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 174 198 1.2E-14 T 01-11-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFULGI_00020790 ec0362710625942aa4e98465fd256343 487 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 144 163 1.2E-14 T 01-11-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFULGI_00020790 ec0362710625942aa4e98465fd256343 487 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 323 342 1.2E-14 T 01-11-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFULGI_00020790 ec0362710625942aa4e98465fd256343 487 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 375 401 1.2E-14 T 01-11-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFULGI_00022880 d0322dd807cd0499c397febd35e7d560 298 SUPERFAMILY SSF51679 18 297 6.39E-10 T 01-11-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFULGI_00022880 d0322dd807cd0499c397febd35e7d560 298 Gene3D G3DSA:3.20.20.30 12 298 2.4E-8 T 01-11-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFULGI_00026260 22fc0e12871235709f322cd8cc2f2d30 136 Gene3D G3DSA:3.30.70.3150 34 124 4.1E-30 T 01-11-2018 AFULGI_00026260 22fc0e12871235709f322cd8cc2f2d30 136 TIGRFAM TIGR00311 aIF-2beta: putative translation initiation factor aIF-2, beta subunit 3 136 1.3E-72 T 01-11-2018 IPR004458 Translation initiation factor 2, beta subunit GO:0003743|GO:0006413 AFULGI_00026260 22fc0e12871235709f322cd8cc2f2d30 136 SMART SM00653 23 130 3.4E-58 T 01-11-2018 IPR002735 Translation initiation factor IF2/IF5 GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 AFULGI_00026260 22fc0e12871235709f322cd8cc2f2d30 136 Pfam PF01873 Domain found in IF2B/IF5 21 130 5.8E-38 T 01-11-2018 IPR002735 Translation initiation factor IF2/IF5 GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 AFULGI_00026260 22fc0e12871235709f322cd8cc2f2d30 136 SUPERFAMILY SSF100966 2 103 5.75E-28 T 01-11-2018 IPR016189 Translation initiation factor IF2/IF5, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 AFULGI_00026260 22fc0e12871235709f322cd8cc2f2d30 136 SUPERFAMILY SSF75689 100 136 9.16E-12 T 01-11-2018 IPR016190 Translation initiation factor IF2/IF5, zinc-binding GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 AFULGI_00026260 22fc0e12871235709f322cd8cc2f2d30 136 Hamap MF_00232 Translation initiation factor 2 subunit beta [eif2b]. 2 136 32.986 T 01-11-2018 IPR004458 Translation initiation factor 2, beta subunit GO:0003743|GO:0006413 AFULGI_00025430 e90e51e7f0c22ff12cdb800fc63c6920 121 SUPERFAMILY SSF52172 4 116 2.99E-32 T 01-11-2018 IPR011006 CheY-like superfamily AFULGI_00025430 e90e51e7f0c22ff12cdb800fc63c6920 121 Pfam PF00072 Response regulator receiver domain 7 112 1.6E-25 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFULGI_00025430 e90e51e7f0c22ff12cdb800fc63c6920 121 SMART SM00448 4 112 1.1E-28 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFULGI_00025430 e90e51e7f0c22ff12cdb800fc63c6920 121 Gene3D G3DSA:3.40.50.2300 2 120 1.9E-34 T 01-11-2018 AFULGI_00018830 048fed9dde319d8c8799a88c2ef633a4 334 Pfam PF01925 Sulfite exporter TauE/SafE 53 319 7.7E-36 T 01-11-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 AFULGI_00003580 40aa5a30450060ac1219d3c66bf40692 468 PIRSF PIRSF019435 1 466 5.9E-173 T 01-11-2018 IPR008508 Protein of unknown function DUF790, endonuclease-like AFULGI_00003580 40aa5a30450060ac1219d3c66bf40692 468 Pfam PF05626 Protein of unknown function (DUF790) 1 376 1.2E-124 T 01-11-2018 IPR008508 Protein of unknown function DUF790, endonuclease-like AFULGI_00003580 40aa5a30450060ac1219d3c66bf40692 468 Gene3D G3DSA:3.40.91.30 267 343 1.7E-5 T 01-11-2018 IPR011578 T7 endonuclease I-like GO:0003677|GO:0004536 AFULGI_00011060 18cb845923ddf8e6d84e5ec5ad2414ab 60 Gene3D G3DSA:3.30.70.20 2 58 2.4E-12 T 01-11-2018 AFULGI_00011060 18cb845923ddf8e6d84e5ec5ad2414ab 60 Pfam PF13187 4Fe-4S dicluster domain 9 54 8.8E-9 T 01-11-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFULGI_00011060 18cb845923ddf8e6d84e5ec5ad2414ab 60 SUPERFAMILY SSF54862 1 57 7.71E-15 T 01-11-2018 AFULGI_00009940 3a9e707e7474e5381f583cad3b2f36dd 251 Pfam PF02596 Uncharacterised ArCR, COG2043 12 211 4.2E-46 T 01-11-2018 IPR003748 Protein of unknown function DUF169 AFULGI_00018570 38495a304252f64f36b8979d43b7b1a6 242 SUPERFAMILY SSF161098 3 240 3.83E-50 T 01-11-2018 IPR035906 MetI-like superfamily AFULGI_00018570 38495a304252f64f36b8979d43b7b1a6 242 Gene3D G3DSA:1.10.3720.10 1 242 7.9E-43 T 01-11-2018 IPR035906 MetI-like superfamily AFULGI_00018570 38495a304252f64f36b8979d43b7b1a6 242 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 64 234 5.6E-12 T 01-11-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFULGI_00006410 20fa303caef31704e6f490b37871c87b 349 Pfam PF01609 Transposase DDE domain 136 325 3.0E-16 T 01-11-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 AFULGI_00000130 7904c0d04d73db307a063704364e3424 491 Gene3D G3DSA:1.20.1730.10 22 490 8.4E-65 T 01-11-2018 IPR038377 Sodium/glucose symporter superfamily AFULGI_00000130 7904c0d04d73db307a063704364e3424 491 ProSitePatterns PS00456 Sodium:solute symporter family signature 1. 153 178 - T 01-11-2018 IPR018212 Sodium/solute symporter, conserved site AFULGI_00000130 7904c0d04d73db307a063704364e3424 491 Pfam PF00474 Sodium:solute symporter family 34 425 2.9E-51 T 01-11-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 AFULGI_00007470 b80998c1bd5dbc22aca6428fd9241fba 61 Pfam PF17253 Family of unknown function (DUF5320) 5 59 2.3E-6 T 01-11-2018 IPR035205 Protein of unknown function DUF5320 AFULGI_00015600 f5bcf5bca9ac863904df3ad584101557 327 Gene3D G3DSA:3.40.1350.10 204 299 1.1E-8 T 01-11-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 AFULGI_00000140 215c6c27f819bcfbe66d989e8c26ddab 215 Pfam PF09719 Putative redox-active protein (C_GCAxxG_C_C) 39 106 2.3E-6 T 01-11-2018 IPR010181 CGCAxxGCC motif AFULGI_00000140 215c6c27f819bcfbe66d989e8c26ddab 215 SUPERFAMILY SSF48695 5 180 3.64E-51 T 01-11-2018 IPR036280 Multiheme cytochrome superfamily AFULGI_00014230 c3b8b16a1928a329f7a4eed4259383ee 250 Pfam PF02596 Uncharacterised ArCR, COG2043 9 211 7.1E-40 T 01-11-2018 IPR003748 Protein of unknown function DUF169 AFULGI_00021230 cd71dd530c412af3ad8b713046e41a9c 335 TIGRFAM TIGR01894 cas_TM1795_cmr1: CRISPR type III-B/RAMP module RAMP protein Cmr1 16 163 2.7E-42 T 01-11-2018 IPR007522 CRISPR-associated protein TM1795 AFULGI_00021230 cd71dd530c412af3ad8b713046e41a9c 335 Pfam PF03787 RAMP superfamily 15 160 9.6E-13 T 01-11-2018 IPR005537 CRISPR type III-associated RAMP protein AFULGI_00017010 2a22ae29975bdd7e825c919752b3649c 102 SUPERFAMILY SSF46785 15 97 2.12E-11 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00017010 2a22ae29975bdd7e825c919752b3649c 102 Pfam PF14947 Winged helix-turn-helix 18 90 3.3E-7 T 01-11-2018 IPR038723 ArnR1-like, winged helix-turn-helix domain AFULGI_00017010 2a22ae29975bdd7e825c919752b3649c 102 Gene3D G3DSA:1.10.10.10 12 93 2.4E-9 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00009380 5292e0f0b86c771340852bc94ac8deff 128 Gene3D G3DSA:2.30.130.90 5 127 5.6E-6 T 01-11-2018 AFULGI_00009380 5292e0f0b86c771340852bc94ac8deff 128 Pfam PF13636 RNA-binding PUA-like domain of methyltransferase RsmF 82 125 2.6E-12 T 01-11-2018 IPR027391 rRNA small subunit methyltransferase F, RNA-binding PUA-like domain AFULGI_00019100 12523b2e98c7d87775b7ff01c6e0fde6 250 Pfam PF12389 Camelysin metallo-endopeptidase 13 46 4.1E-6 T 01-11-2018 IPR022121 Peptidase M73, camelysin AFULGI_00019100 12523b2e98c7d87775b7ff01c6e0fde6 250 TIGRFAM TIGR04088 cognate_SipW: SipW-cognate class signal peptide 9 41 4.0E-11 T 01-11-2018 IPR023833 Signal peptide, camelysin AFULGI_00006720 eb3e627acd04056578770b629ff05e81 87 Pfam PF03683 Uncharacterised protein family (UPF0175) 12 81 3.4E-23 T 01-11-2018 IPR005368 Uncharacterised protein family UPF0175 AFULGI_00005970 8152e4e00e9a882ba69424fb9508767f 1419 SUPERFAMILY SSF52540 34 312 1.1E-7 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00000610 71b15b116dea7d678687d7bf74fb59a3 317 Pfam PF01905 CRISPR-associated negative auto-regulator DevR/Csa2 9 278 1.3E-73 T 01-11-2018 IPR010154 CRISPR-associated protein Cas7/Cst2/DevR AFULGI_00000610 71b15b116dea7d678687d7bf74fb59a3 317 TIGRFAM TIGR01875 cas_MJ0381: CRISPR-associated autoregulator DevR family 7 262 1.4E-58 T 01-11-2018 IPR010154 CRISPR-associated protein Cas7/Cst2/DevR AFULGI_00011770 0ebb84ed697c576f3a093231ce168220 130 Pfam PF01850 PIN domain 3 125 9.4E-30 T 01-11-2018 IPR002716 PIN domain AFULGI_00011770 0ebb84ed697c576f3a093231ce168220 130 SMART SM00670 1 121 7.1E-25 T 01-11-2018 IPR002716 PIN domain AFULGI_00011770 0ebb84ed697c576f3a093231ce168220 130 Gene3D G3DSA:3.40.50.1010 2 129 8.4E-17 T 01-11-2018 AFULGI_00011770 0ebb84ed697c576f3a093231ce168220 130 SUPERFAMILY SSF88723 1 124 3.36E-23 T 01-11-2018 IPR029060 PIN-like domain superfamily AFULGI_00011770 0ebb84ed697c576f3a093231ce168220 130 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 3 129 10.84 T 01-11-2018 IPR022907 VapC family GO:0004540 AFULGI_00001160 72a62d9ce72922dd961f196db2beb395 439 Pfam PF01629 Domain of unknown function DUF22 287 392 4.9E-40 T 01-11-2018 IPR002572 Domain of unknown function DUF22 AFULGI_00001160 72a62d9ce72922dd961f196db2beb395 439 Pfam PF01629 Domain of unknown function DUF22 2 110 6.2E-39 T 01-11-2018 IPR002572 Domain of unknown function DUF22 AFULGI_00001160 72a62d9ce72922dd961f196db2beb395 439 Pfam PF01629 Domain of unknown function DUF22 150 255 3.8E-41 T 01-11-2018 IPR002572 Domain of unknown function DUF22 AFULGI_00024940 9f0d1b91667543f00911d10288e9c41d 131 TIGRFAM TIGR03081 metmalonyl_epim: methylmalonyl-CoA epimerase 4 130 2.9E-53 T 01-11-2018 IPR017515 Methylmalonyl-CoA epimerase KEGG: 00280+5.1.99.1|KEGG: 00630+5.1.99.1|KEGG: 00640+5.1.99.1|KEGG: 00720+5.1.99.1|MetaCyc: PWY-5741|MetaCyc: PWY-5743|MetaCyc: PWY-5789|MetaCyc: PWY-6728|MetaCyc: PWY-7384|MetaCyc: PWY-7854|Reactome: R-HSA-71032 AFULGI_00024940 9f0d1b91667543f00911d10288e9c41d 131 Gene3D G3DSA:3.10.180.10 1 130 8.9E-42 T 01-11-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFULGI_00024940 9f0d1b91667543f00911d10288e9c41d 131 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 115 6.7E-24 T 01-11-2018 AFULGI_00024940 9f0d1b91667543f00911d10288e9c41d 131 SUPERFAMILY SSF54593 2 130 9.9E-34 T 01-11-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFULGI_00017790 123236d8aad414ff68a211b08dca6752 285 Pfam PF01925 Sulfite exporter TauE/SafE 8 272 6.8E-37 T 01-11-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 AFULGI_00009890 290c6053bee021e8e64158b35a429ed2 165 Gene3D G3DSA:1.10.10.10 11 104 4.4E-23 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00009890 290c6053bee021e8e64158b35a429ed2 165 SUPERFAMILY SSF46785 25 102 8.19E-10 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00006800 e9c73977e84a382d4f86ef0254d2b5d5 152 SUPERFAMILY SSF52540 26 133 3.96E-7 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00020200 ba4415537af72f3f3e4779005b2f104a 286 Gene3D G3DSA:1.10.3720.10 73 283 8.9E-23 T 01-11-2018 IPR035906 MetI-like superfamily AFULGI_00020200 ba4415537af72f3f3e4779005b2f104a 286 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 101 283 6.0E-24 T 01-11-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFULGI_00020200 ba4415537af72f3f3e4779005b2f104a 286 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 26 60 3.1E-8 T 01-11-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain AFULGI_00020200 ba4415537af72f3f3e4779005b2f104a 286 SUPERFAMILY SSF161098 79 267 1.96E-26 T 01-11-2018 IPR035906 MetI-like superfamily AFULGI_00017700 908c5f8951a3e2e48affe9caaac084ea 162 Gene3D G3DSA:3.40.630.30 13 162 1.9E-23 T 01-11-2018 AFULGI_00017700 908c5f8951a3e2e48affe9caaac084ea 162 SUPERFAMILY SSF55729 24 155 4.05E-23 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase AFULGI_00017700 908c5f8951a3e2e48affe9caaac084ea 162 Pfam PF00583 Acetyltransferase (GNAT) family 49 146 6.8E-15 T 01-11-2018 IPR000182 GNAT domain AFULGI_00025850 7b68823e9701b98e675c6ac4f5b52860 316 Hamap MF_00354 Isopentenyl-diphosphate delta-isomerase [fni]. 1 306 36.326 T 01-11-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 AFULGI_00025850 7b68823e9701b98e675c6ac4f5b52860 316 SMART SM01240 5 308 0.0031 T 01-11-2018 AFULGI_00025850 7b68823e9701b98e675c6ac4f5b52860 316 TIGRFAM TIGR02151 IPP_isom_2: isopentenyl-diphosphate delta-isomerase, type 2 2 305 2.4E-116 T 01-11-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 AFULGI_00025850 7b68823e9701b98e675c6ac4f5b52860 316 PIRSF PIRSF003314 1 316 1.1E-118 T 01-11-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 AFULGI_00025850 7b68823e9701b98e675c6ac4f5b52860 316 Pfam PF01070 FMN-dependent dehydrogenase 141 298 3.6E-16 T 01-11-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 Reactome: R-HSA-9033241 AFULGI_00025850 7b68823e9701b98e675c6ac4f5b52860 316 Gene3D G3DSA:3.20.20.70 1 316 1.6E-115 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFULGI_00025850 7b68823e9701b98e675c6ac4f5b52860 316 SUPERFAMILY SSF51395 2 314 4.97E-79 T 01-11-2018 AFULGI_00022270 64ac4232be263be99afb79aeb21ed9d7 334 SUPERFAMILY SSF81301 77 149 8.88E-5 T 01-11-2018 AFULGI_00022270 64ac4232be263be99afb79aeb21ed9d7 334 Pfam PF01909 Nucleotidyltransferase domain 102 190 3.4E-7 T 01-11-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 AFULGI_00005270 d80bd43493918e22bf18e781430c4409 236 Pfam PF06745 KaiC 4 229 1.2E-24 T 01-11-2018 IPR014774 KaiC-like domain AFULGI_00005270 d80bd43493918e22bf18e781430c4409 236 SUPERFAMILY SSF52540 3 229 3.49E-22 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00005270 d80bd43493918e22bf18e781430c4409 236 Gene3D G3DSA:3.40.50.300 1 233 2.1E-36 T 01-11-2018 AFULGI_00018380 6841e2674059f18d0225d9bb14d7f814 437 Gene3D G3DSA:3.30.70.150 18 149 1.2E-38 T 01-11-2018 IPR036422 RuBisCO large subunit, N-terminal domain superfamily GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 AFULGI_00018380 6841e2674059f18d0225d9bb14d7f814 437 SUPERFAMILY SSF51649 149 427 2.62E-89 T 01-11-2018 IPR036376 Ribulose bisphosphate carboxylase, large subunit, C-terminal domain superfamily GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 AFULGI_00018380 6841e2674059f18d0225d9bb14d7f814 437 Gene3D G3DSA:3.20.20.110 150 437 3.3E-102 T 01-11-2018 IPR036376 Ribulose bisphosphate carboxylase, large subunit, C-terminal domain superfamily GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 AFULGI_00018380 6841e2674059f18d0225d9bb14d7f814 437 Pfam PF00016 Ribulose bisphosphate carboxylase large chain, catalytic domain 155 435 1.1E-55 T 01-11-2018 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 AFULGI_00018380 6841e2674059f18d0225d9bb14d7f814 437 Pfam PF02788 Ribulose bisphosphate carboxylase large chain, N-terminal domain 30 145 6.8E-9 T 01-11-2018 IPR017443 Ribulose bisphosphate carboxylase, large subunit, ferrodoxin-like N-terminal GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 AFULGI_00018380 6841e2674059f18d0225d9bb14d7f814 437 SUPERFAMILY SSF54966 23 149 2.09E-35 T 01-11-2018 IPR036422 RuBisCO large subunit, N-terminal domain superfamily GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 AFULGI_00017530 2202fb7c8833a2273a8e98729a1f3054 247 Pfam PF09987 Uncharacterized protein conserved in archaea (DUF2226) 121 240 2.8E-38 T 01-11-2018 IPR019249 Protein of unknown function DUF2226 AFULGI_00017530 2202fb7c8833a2273a8e98729a1f3054 247 Pfam PF09987 Uncharacterized protein conserved in archaea (DUF2226) 1 120 6.3E-41 T 01-11-2018 IPR019249 Protein of unknown function DUF2226 AFULGI_00021300 7ca8fcc299f070c6f77a3ba77df42e50 112 TIGRFAM TIGR01878 cas_Csa5: CRISPR type I-A/APERN-associated protein Csa5 14 105 4.3E-20 T 01-11-2018 IPR010157 CRISPR type I-A/APERN-associated protein Csa5 AFULGI_00010150 3213ce67b29b559cb18007d1764dd904 139 SUPERFAMILY SSF54637 2 135 4.93E-27 T 01-11-2018 IPR029069 HotDog domain superfamily AFULGI_00010150 3213ce67b29b559cb18007d1764dd904 139 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 23 131 1.8E-22 T 01-11-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 AFULGI_00010150 3213ce67b29b559cb18007d1764dd904 139 Gene3D G3DSA:3.10.129.10 12 138 1.2E-31 T 01-11-2018 AFULGI_00010150 3213ce67b29b559cb18007d1764dd904 139 Pfam PF03061 Thioesterase superfamily 47 124 1.7E-14 T 01-11-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 AFULGI_00008400 bfd86dbf44c0a184d286d561d3c74fc1 258 TIGRFAM TIGR02537 arch_flag_Nterm: archaeal flagellin N-terminal-like domain 4 26 1.8E-4 T 01-11-2018 IPR013373 Flagellin/pilin, N-terminal AFULGI_00018370 def829bcab62b0d0fa4bb3d786127eeb 109 Gene3D G3DSA:3.30.460.10 19 109 2.0E-17 T 01-11-2018 AFULGI_00018370 def829bcab62b0d0fa4bb3d786127eeb 109 SUPERFAMILY SSF81301 23 106 9.12E-16 T 01-11-2018 AFULGI_00018370 def829bcab62b0d0fa4bb3d786127eeb 109 Pfam PF01909 Nucleotidyltransferase domain 23 98 1.1E-10 T 01-11-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 AFULGI_00017440 7da8e5f4f1bf19d195efdaf9e4e15e7f 106 Gene3D G3DSA:1.10.10.1410 1 58 5.1E-31 T 01-11-2018 IPR038716 Ribosomal protein P1/P2, N-terminal domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00017440 7da8e5f4f1bf19d195efdaf9e4e15e7f 106 Pfam PF00428 60s Acidic ribosomal protein 16 105 7.6E-22 T 01-11-2018 AFULGI_00017440 7da8e5f4f1bf19d195efdaf9e4e15e7f 106 Hamap MF_01478 50S ribosomal protein L12 [rpl12]. 1 106 14.701 T 01-11-2018 IPR027534 Ribosomal protein L12 family GO:0003735|GO:0005622|GO:0005840|GO:0006414 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00017440 7da8e5f4f1bf19d195efdaf9e4e15e7f 106 TIGRFAM TIGR03685 ribo_P1_arch: 50S ribosomal protein P1 1 106 9.8E-44 T 01-11-2018 IPR022295 Ribosomal protein L12, archaea GO:0003735|GO:0005840|GO:0006414 AFULGI_00017450 603e735f31486569cd890647df5db914 67 SUPERFAMILY SSF47113 3 66 4.05E-19 T 01-11-2018 IPR009072 Histone-fold GO:0046982 AFULGI_00017450 603e735f31486569cd890647df5db914 67 Pfam PF00808 Histone-like transcription factor (CBF/NF-Y) and archaeal histone 2 65 5.3E-21 T 01-11-2018 IPR003958 Transcription factor CBF/NF-Y/archaeal histone domain AFULGI_00017450 603e735f31486569cd890647df5db914 67 Gene3D G3DSA:1.10.20.10 1 66 3.7E-22 T 01-11-2018 IPR009072 Histone-fold GO:0046982 AFULGI_00019680 775a976f229296bdde35cc25a944bcbe 137 Pfam PF07849 Protein of unknown function (DUF1641) 103 135 2.8E-14 T 01-11-2018 IPR012440 Protein of unknown function DUF1641 AFULGI_00025250 b7d6eaa427fe4b558858b1a036898903 128 SUPERFAMILY SSF46785 4 111 1.63E-18 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00025250 b7d6eaa427fe4b558858b1a036898903 128 Pfam PF01475 Ferric uptake regulator family 12 125 4.2E-24 T 01-11-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 AFULGI_00025250 b7d6eaa427fe4b558858b1a036898903 128 Gene3D G3DSA:1.10.10.10 3 82 7.2E-18 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00007950 a4845d1870a5a08f3bb8e32820a49498 223 SUPERFAMILY SSF51366 1 219 6.0E-23 T 01-11-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 AFULGI_00007950 a4845d1870a5a08f3bb8e32820a49498 223 Gene3D G3DSA:3.20.20.70 1 220 2.9E-26 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFULGI_00007950 a4845d1870a5a08f3bb8e32820a49498 223 TIGRFAM TIGR00734 hisAF_rel: hisA/hisF family protein 1 213 1.1E-98 T 01-11-2018 IPR004650 HisA/HisF-like protein AFULGI_00007950 a4845d1870a5a08f3bb8e32820a49498 223 Pfam PF00977 Histidine biosynthesis protein 3 213 5.5E-16 T 01-11-2018 IPR006062 Histidine biosynthesis GO:0000105 AFULGI_00001110 fc35223b37ce01bfd8da0e7df1df3dc7 89 ProSitePatterns PS00414 Profilin signature. 1 9 - T 01-11-2018 IPR027310 Profilin conserved site GO:0003779 Reactome: R-HSA-376176|Reactome: R-HSA-5663220 AFULGI_00001110 fc35223b37ce01bfd8da0e7df1df3dc7 89 Gene3D G3DSA:1.10.10.10 1 89 6.9E-30 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00001110 fc35223b37ce01bfd8da0e7df1df3dc7 89 SUPERFAMILY SSF46785 10 79 8.74E-15 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00001110 fc35223b37ce01bfd8da0e7df1df3dc7 89 Pfam PF12840 Helix-turn-helix domain 20 71 2.0E-11 T 01-11-2018 AFULGI_00002150 ac09cb84c1e0e129ab3c6cc0a669f3ef 323 Hamap MF_01244 3-dehydroquinate synthase [aroB']. 1 323 38.181 T 01-11-2018 IPR002812 3-dehydroquinate synthase GO:0003856|GO:0009073|GO:0016491|GO:0055114 KEGG: 00400+1.4.1.24|MetaCyc: PWY-6160 AFULGI_00002150 ac09cb84c1e0e129ab3c6cc0a669f3ef 323 ProDom PD017907 3-DEHYDROQUINATE UPF0245 SYNTHASE LYASE PREDICTED SYNTHASE-LIKE ALTERNATIVE T19N8 MM1272 MK1408 16 322 1.0E-166 T 01-11-2018 IPR002812 3-dehydroquinate synthase GO:0003856|GO:0009073|GO:0016491|GO:0055114 KEGG: 00400+1.4.1.24|MetaCyc: PWY-6160 AFULGI_00002150 ac09cb84c1e0e129ab3c6cc0a669f3ef 323 PIRSF PIRSF006655 53 323 6.9E-120 T 01-11-2018 IPR002812 3-dehydroquinate synthase GO:0003856|GO:0009073|GO:0016491|GO:0055114 KEGG: 00400+1.4.1.24|MetaCyc: PWY-6160 AFULGI_00002150 ac09cb84c1e0e129ab3c6cc0a669f3ef 323 PIRSF PIRSF006655 1 66 3.3E-5 T 01-11-2018 IPR002812 3-dehydroquinate synthase GO:0003856|GO:0009073|GO:0016491|GO:0055114 KEGG: 00400+1.4.1.24|MetaCyc: PWY-6160 AFULGI_00002150 ac09cb84c1e0e129ab3c6cc0a669f3ef 323 Pfam PF01959 3-dehydroquinate synthase (EC 4.6.1.3) 55 323 2.0E-113 T 01-11-2018 IPR002812 3-dehydroquinate synthase GO:0003856|GO:0009073|GO:0016491|GO:0055114 KEGG: 00400+1.4.1.24|MetaCyc: PWY-6160 AFULGI_00002150 ac09cb84c1e0e129ab3c6cc0a669f3ef 323 Pfam PF01959 3-dehydroquinate synthase (EC 4.6.1.3) 2 70 2.0E-6 T 01-11-2018 IPR002812 3-dehydroquinate synthase GO:0003856|GO:0009073|GO:0016491|GO:0055114 KEGG: 00400+1.4.1.24|MetaCyc: PWY-6160 AFULGI_00008950 f827d780aad2de288594185f8d9e350f 300 Pfam PF02754 Cysteine-rich domain 205 286 1.1E-6 T 01-11-2018 IPR004017 Cysteine-rich domain AFULGI_00003690 4a278d35850819ce83a17678381a2e3f 58 Pfam PF10047 Protein of unknown function (DUF2281) 5 57 3.0E-15 T 01-11-2018 IPR018739 Domain of unknown function DUF2281 AFULGI_00012890 b1a9460704e6299bcbd9f71703be9b5f 295 PIRSF PIRSF000105 1 295 4.4E-85 T 01-11-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 AFULGI_00012890 b1a9460704e6299bcbd9f71703be9b5f 295 Gene3D G3DSA:3.40.50.720 1 190 7.8E-72 T 01-11-2018 AFULGI_00012890 b1a9460704e6299bcbd9f71703be9b5f 295 SUPERFAMILY SSF51735 6 190 1.26E-59 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily AFULGI_00012890 b1a9460704e6299bcbd9f71703be9b5f 295 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 192 290 6.0E-28 T 01-11-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 AFULGI_00012890 b1a9460704e6299bcbd9f71703be9b5f 295 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 9 189 3.1E-69 T 01-11-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 AFULGI_00012890 b1a9460704e6299bcbd9f71703be9b5f 295 SUPERFAMILY SSF48179 191 291 3.57E-25 T 01-11-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AFULGI_00012890 b1a9460704e6299bcbd9f71703be9b5f 295 Gene3D G3DSA:1.10.1040.10 192 295 4.9E-27 T 01-11-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AFULGI_00026010 127fc29c4538f5bb54953f7bf320cd24 208 Pfam PF14401 RimK-like ATPgrasp N-terminal domain 17 177 3.4E-17 T 01-11-2018 IPR025839 RimK-like ATPgrasp N-terminal domain AFULGI_00011580 59591347e717b4a597d8be5076a03ed9 52 SUPERFAMILY SSF143011 1 49 2.35E-9 T 01-11-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily AFULGI_00011580 59591347e717b4a597d8be5076a03ed9 52 Gene3D G3DSA:3.30.2310.20 1 52 1.1E-5 T 01-11-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily AFULGI_00016480 15a2fe1aecbdbd2958b0b89b8c841746 216 Pfam PF04893 Yip1 domain 3 204 1.3E-29 T 01-11-2018 IPR006977 Yip1 domain GO:0016020 AFULGI_00011630 722f0dc7f6034732725afd05d88cdfce 620 Gene3D G3DSA:3.40.630.30 185 341 4.0E-6 T 01-11-2018 AFULGI_00011630 722f0dc7f6034732725afd05d88cdfce 620 SUPERFAMILY SSF52540 412 618 2.21E-33 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00011630 722f0dc7f6034732725afd05d88cdfce 620 Gene3D G3DSA:3.40.50.300 389 620 3.0E-38 T 01-11-2018 AFULGI_00011630 722f0dc7f6034732725afd05d88cdfce 620 SMART SM00382 437 615 8.8E-14 T 01-11-2018 IPR003593 AAA+ ATPase domain AFULGI_00011630 722f0dc7f6034732725afd05d88cdfce 620 SUPERFAMILY SSF55729 269 337 3.09E-6 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase AFULGI_00011630 722f0dc7f6034732725afd05d88cdfce 620 Pfam PF00005 ABC transporter 428 563 6.4E-19 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFULGI_00019270 6a68f2b39c0d52c1315c749eac2cf14d 207 SUPERFAMILY SSF55718 1 205 3.83E-28 T 01-11-2018 IPR036527 SCP2 sterol-binding domain superfamily AFULGI_00019270 6a68f2b39c0d52c1315c749eac2cf14d 207 Pfam PF02036 SCP-2 sterol transfer family 100 190 7.4E-20 T 01-11-2018 IPR003033 SCP2 sterol-binding domain AFULGI_00019270 6a68f2b39c0d52c1315c749eac2cf14d 207 Gene3D G3DSA:3.30.1050.10 79 201 2.5E-19 T 01-11-2018 IPR036527 SCP2 sterol-binding domain superfamily AFULGI_00012830 ac86e41abccc5d68ff2cd4ffecc34330 107 Pfam PF09845 Zn-ribbon containing protein 48 101 6.2E-15 T 01-11-2018 IPR018645 Zn-ribbon containing protein AFULGI_00001960 994fbe71fefe9b805f7bb3c7b64cb785 498 Pfam PF09843 Predicted membrane protein (DUF2070) 5 490 2.3E-73 T 01-11-2018 IPR019204 Domain of unknown function DUF2070, membrane AFULGI_00026670 764dcadd41459e5ec715941815973187 96 SUPERFAMILY SSF46785 30 95 1.01E-11 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00026670 764dcadd41459e5ec715941815973187 96 Pfam PF01022 Bacterial regulatory protein, arsR family 27 71 1.9E-12 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFULGI_00026670 764dcadd41459e5ec715941815973187 96 Gene3D G3DSA:1.10.10.10 9 95 1.9E-11 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFULGI_00000490 6842ab070c69cbe8f40d876611882564 46 Hamap MF_00615 DNA-directed RNA polymerase subunit P [rpoP]. 3 46 14.216 T 01-11-2018 IPR023464 DNA-directed RNA polymerase subunit P (Rpo12) GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFULGI_00000490 6842ab070c69cbe8f40d876611882564 46 Pfam PF03604 DNA directed RNA polymerase, 7 kDa subunit 3 35 1.1E-8 T 01-11-2018 IPR006591 RNA polymerase archaeal subunit P/eukaryotic subunit RPABC4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 AFULGI_00000490 6842ab070c69cbe8f40d876611882564 46 SUPERFAMILY SSF63393 1 38 1.31E-9 T 01-11-2018 IPR029040 RNA polymerase subunit RPABC4/transcription elongation factor Spt4 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-75955 AFULGI_00000490 6842ab070c69cbe8f40d876611882564 46 SMART SM00659 1 46 1.0E-20 T 01-11-2018 IPR006591 RNA polymerase archaeal subunit P/eukaryotic subunit RPABC4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 AFULGI_00000490 6842ab070c69cbe8f40d876611882564 46 Gene3D G3DSA:2.20.28.30 1 46 1.2E-16 T 01-11-2018 AFULGI_00006030 96bc5b6654588e1ecabce8a7a54f4233 549 Gene3D G3DSA:1.10.1670.10 298 363 2.1E-19 T 01-11-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 AFULGI_00006030 96bc5b6654588e1ecabce8a7a54f4233 549 Pfam PF09171 N-glycosylase/DNA lyase 135 361 2.6E-22 T 01-11-2018 IPR015254 N-glycosylase/DNA lyase-like GO:0003906|GO:0016799 AFULGI_00006030 96bc5b6654588e1ecabce8a7a54f4233 549 SUPERFAMILY SSF48150 128 363 1.41E-48 T 01-11-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 AFULGI_00006030 96bc5b6654588e1ecabce8a7a54f4233 549 Gene3D G3DSA:1.10.340.30 153 297 2.1E-19 T 01-11-2018 AFULGI_00010790 946b58f2f01bb579613d859ec6a2d00e 234 Pfam PF00005 ABC transporter 19 162 2.4E-30 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFULGI_00010790 946b58f2f01bb579613d859ec6a2d00e 234 Gene3D G3DSA:3.40.50.300 1 234 1.0E-62 T 01-11-2018 AFULGI_00010790 946b58f2f01bb579613d859ec6a2d00e 234 SMART SM00382 26 219 1.6E-5 T 01-11-2018 IPR003593 AAA+ ATPase domain AFULGI_00010790 946b58f2f01bb579613d859ec6a2d00e 234 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFULGI_00010790 946b58f2f01bb579613d859ec6a2d00e 234 SUPERFAMILY SSF52540 2 232 9.67E-60 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00005420 f5cda22d7f1df5cd6e05e014b909c7da 206 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 192 3.9E-19 T 01-11-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 AFULGI_00005420 f5cda22d7f1df5cd6e05e014b909c7da 206 SUPERFAMILY SSF56300 1 204 1.97E-57 T 01-11-2018 AFULGI_00005420 f5cda22d7f1df5cd6e05e014b909c7da 206 Gene3D G3DSA:3.60.21.10 1 206 4.4E-24 T 01-11-2018 IPR029052 Metallo-dependent phosphatase-like AFULGI_00011710 222ba8ffe762e9abed8420b6b692fc6e 54 Gene3D G3DSA:3.30.420.10 5 43 7.1E-6 T 01-11-2018 IPR036397 Ribonuclease H superfamily GO:0003676 AFULGI_00020050 75b911480cb0306fa4c8be45dd3616ae 100 Pfam PF05437 Branched-chain amino acid transport protein (AzlD) 6 97 3.0E-14 T 01-11-2018 IPR008407 Branched-chain amino acid transport, AzlD AFULGI_00014470 82e06472a5d9bb66a7f8a884cbd93076 290 TIGRFAM TIGR00380 cobD: cobalamin biosynthesis protein CobD 3 284 7.4E-124 T 01-11-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 AFULGI_00014470 82e06472a5d9bb66a7f8a884cbd93076 290 Hamap MF_00024 Cobalamin biosynthesis protein CbiB [cbiB]. 1 288 65.317 T 01-11-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 AFULGI_00014470 82e06472a5d9bb66a7f8a884cbd93076 290 Pfam PF03186 CobD/Cbib protein 9 261 7.0E-75 T 01-11-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 AFULGI_00002470 5ce0b60d302d6c12b14848de9c24c5f3 62 Pfam PF01909 Nucleotidyltransferase domain 7 52 3.5E-12 T 01-11-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 AFULGI_00002470 5ce0b60d302d6c12b14848de9c24c5f3 62 SUPERFAMILY SSF81301 4 51 6.54E-15 T 01-11-2018 AFULGI_00002470 5ce0b60d302d6c12b14848de9c24c5f3 62 Gene3D G3DSA:3.30.460.10 2 61 1.8E-14 T 01-11-2018 AFULGI_00000420 b058befee7e724237f725bd91426ce54 506 Pfam PF01364 Peptidase family C25 23 415 8.8E-55 T 01-11-2018 IPR001769 Gingipain GO:0006508|GO:0008234 AFULGI_00000420 b058befee7e724237f725bd91426ce54 506 SUPERFAMILY SSF52129 22 341 8.27E-17 T 01-11-2018 IPR029030 Caspase-like domain superfamily AFULGI_00018400 88af74e0cc10d0cefe47a22cf73ed84c 623 Pfam PF04894 Archaeal Nre, N-terminal 10 251 8.7E-93 T 01-11-2018 IPR006978 Archaeal Nre, N-terminal AFULGI_00018400 88af74e0cc10d0cefe47a22cf73ed84c 623 SUPERFAMILY SSF102114 392 547 7.46E-6 T 01-11-2018 AFULGI_00018400 88af74e0cc10d0cefe47a22cf73ed84c 623 Hamap MF_02096 DNA repair protein. 1 397 34.698 T 01-11-2018 IPR033167 Archaeal Nre GO:0006281 AFULGI_00018400 88af74e0cc10d0cefe47a22cf73ed84c 623 Pfam PF04895 Archaeal Nre, C-terminal 263 364 7.0E-35 T 01-11-2018 IPR006979 Archaeal Nre, C-terminal AFULGI_00018400 88af74e0cc10d0cefe47a22cf73ed84c 623 Pfam PF04055 Radical SAM superfamily 394 548 2.9E-8 T 01-11-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFULGI_00020130 c80bf3061429f5e19ebc259b812a5d57 61 SUPERFAMILY SSF52096 2 32 2.24E-5 T 01-11-2018 IPR029045 ClpP/crotonase-like domain superfamily AFULGI_00020130 c80bf3061429f5e19ebc259b812a5d57 61 Gene3D G3DSA:3.30.300.220 1 50 3.0E-5 T 01-11-2018 AFULGI_00016220 4e7024decd07f50aeafe1f3ddbd5da2c 70 Pfam PF10049 Protein of unknown function (DUF2283) 3 49 3.2E-10 T 01-11-2018 IPR019270 Protein of unknown function DUF2283 AFULGI_00011850 b5b11d8e8bcd090991942fcbc49aaf8c 95 Pfam PF01850 PIN domain 26 74 8.1E-7 T 01-11-2018 IPR002716 PIN domain AFULGI_00011850 b5b11d8e8bcd090991942fcbc49aaf8c 95 Gene3D G3DSA:3.40.50.1010 8 83 2.5E-7 T 01-11-2018 AFULGI_00011850 b5b11d8e8bcd090991942fcbc49aaf8c 95 SUPERFAMILY SSF88723 5 93 5.33E-13 T 01-11-2018 IPR029060 PIN-like domain superfamily AFULGI_00008850 8dd4d6ade85973393f19b44ef5b2e2a1 168 Pfam PF09622 Putative integral membrane protein (DUF2391) 42 163 1.4E-8 T 01-11-2018 IPR024464 Protein of unknown function DUF2391 AFULGI_00003280 84adae024a12d754108ff5b44f2f6c63 591 Pfam PF02516 Oligosaccharyl transferase STT3 subunit 9 483 4.7E-16 T 01-11-2018 IPR003674 Oligosaccharyl transferase, STT3 subunit GO:0004576|GO:0006486|GO:0016020 AFULGI_00003280 84adae024a12d754108ff5b44f2f6c63 591 Gene3D G3DSA:3.40.50.12610 429 591 1.2E-54 T 01-11-2018 AFULGI_00020520 7d19346492ca628e9e0b63e8186cdd53 340 Pfam PF01594 AI-2E family transporter 9 325 2.7E-69 T 01-11-2018 IPR002549 Transmembrane protein TqsA-like AFULGI_00019930 f703b461cdcee7c07d48c778c9b355ce 312 PIRSF PIRSF012876 1 312 8.7E-156 T 01-11-2018 IPR014466 Predicted transcriptional regulator, AF1742 type AFULGI_00019930 f703b461cdcee7c07d48c778c9b355ce 312 Gene3D G3DSA:3.40.190.10 161 306 1.5E-10 T 01-11-2018 AFULGI_00019930 f703b461cdcee7c07d48c778c9b355ce 312 SUPERFAMILY SSF46785 6 60 6.12E-6 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily AFULGI_00004750 8084e6ad4bf4c62457425d931d9ab267 344 TIGRFAM TIGR02122 TRAP_TAXI: TRAP transporter solute receptor, TAXI family 6 335 4.2E-78 T 01-11-2018 IPR011852 TRAP transporter solute receptor, TAXI family AFULGI_00004750 8084e6ad4bf4c62457425d931d9ab267 344 SUPERFAMILY SSF53850 49 336 2.01E-65 T 01-11-2018 AFULGI_00004750 8084e6ad4bf4c62457425d931d9ab267 344 Pfam PF16868 NMT1-like family 52 335 3.5E-65 T 01-11-2018 IPR011852 TRAP transporter solute receptor, TAXI family AFULGI_00004750 8084e6ad4bf4c62457425d931d9ab267 344 Gene3D G3DSA:3.40.190.10 136 272 5.8E-89 T 01-11-2018 AFULGI_00004750 8084e6ad4bf4c62457425d931d9ab267 344 Gene3D G3DSA:3.40.190.10 53 335 5.8E-89 T 01-11-2018 AFULGI_00023230 b41003aeec733df451cfc3a61cfea2ac 172 TIGRFAM TIGR02175 PorC_KorC: 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family 2 170 6.5E-38 T 01-11-2018 IPR011894 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0055114 AFULGI_00023230 b41003aeec733df451cfc3a61cfea2ac 172 SUPERFAMILY SSF53323 2 169 2.48E-27 T 01-11-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 AFULGI_00023230 b41003aeec733df451cfc3a61cfea2ac 172 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 11 166 2.7E-24 T 01-11-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 AFULGI_00023230 b41003aeec733df451cfc3a61cfea2ac 172 Gene3D G3DSA:3.40.920.10 2 171 6.3E-37 T 01-11-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 AFULGI_00024520 9fc5dc3693ed305d72ed04dde2d4d93e 212 Pfam PF01930 Domain of unknown function DUF83 141 201 2.9E-5 T 01-11-2018 IPR022765 Dna2/Cas4, domain of unknown function DUF83 AFULGI_00020430 ee07820be6fbb80c29bac45db65415ab 120 Pfam PF09946 Predicted membrane protein (DUF2178) 9 107 2.2E-28 T 01-11-2018 IPR019235 Protein of unknown function DUF2178, transmembrane AFULGI_00020920 9c0ffef3e38d2cf498588107888374db 53 Gene3D G3DSA:3.40.50.10800 3 50 3.5E-13 T 01-11-2018 AFULGI_00020920 9c0ffef3e38d2cf498588107888374db 53 Pfam PF02445 Quinolinate synthetase A protein 8 42 2.8E-10 T 01-11-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 AFULGI_00020920 9c0ffef3e38d2cf498588107888374db 53 SUPERFAMILY SSF142754 6 42 3.92E-11 T 01-11-2018 IPR036094 Quinolinate synthetase A superfamily GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 AFULGI_00019560 f40e740d8238e84a49d71df7c50d4a8c 219 Pfam PF01863 Protein of unknown function DUF45 11 202 2.1E-45 T 01-11-2018 IPR002725 Protein of unknown function DUF45 AFULGI_00019560 f40e740d8238e84a49d71df7c50d4a8c 219 Gene3D G3DSA:3.30.2010.10 111 205 2.6E-17 T 01-11-2018 AFULGI_00001890 215c2740e8a2bb8627da222867d1a90e 196 Pfam PF01976 Protein of unknown function DUF116 22 177 8.8E-44 T 01-11-2018 IPR002829 Protein of unknown function DUF116 AFULGI_00001890 215c2740e8a2bb8627da222867d1a90e 196 PIRSF PIRSF006594 1 184 3.9E-69 T 01-11-2018 IPR002829 Protein of unknown function DUF116 AFULGI_00017880 c313906dffbbb7a2d7050ad73ee72491 92 Gene3D G3DSA:3.30.1050.10 1 92 2.4E-32 T 01-11-2018 IPR036527 SCP2 sterol-binding domain superfamily AFULGI_00017880 c313906dffbbb7a2d7050ad73ee72491 92 Pfam PF02036 SCP-2 sterol transfer family 2 84 4.1E-14 T 01-11-2018 IPR003033 SCP2 sterol-binding domain AFULGI_00017880 c313906dffbbb7a2d7050ad73ee72491 92 SUPERFAMILY SSF55718 2 90 4.0E-18 T 01-11-2018 IPR036527 SCP2 sterol-binding domain superfamily AFULGI_00018150 6eb54a1a82dfa9879ed90f439b6021be 137 ProDom PD085044 MEMBRANE AF1562 TRANSMEMBRANE 28 115 1.0E-45 T 01-11-2018 IPR020327 Uncharacterised protein family AF1562 AFULGI_00008050 715af569081183cef323d914e2a778a5 240 Pfam PF01890 Cobalamin synthesis G C-terminus 127 239 3.7E-25 T 01-11-2018 IPR002750 CobE/GbiG C-terminal domain GO:0009236 AFULGI_00008050 715af569081183cef323d914e2a778a5 240 SUPERFAMILY SSF159672 17 130 7.19E-25 T 01-11-2018 IPR038029 GbiG N-terminal domain superfamily KEGG: 00860+3.7.1.12|MetaCyc: PWY-7377 AFULGI_00008050 715af569081183cef323d914e2a778a5 240 Pfam PF11760 Cobalamin synthesis G N-terminal 50 120 1.7E-22 T 01-11-2018 IPR021744 Cobalamin synthesis G, N-terminal KEGG: 00860+3.7.1.12|MetaCyc: PWY-7377 AFULGI_00008050 715af569081183cef323d914e2a778a5 240 Gene3D G3DSA:3.40.50.11220 5 116 6.4E-21 T 01-11-2018 AFULGI_00008050 715af569081183cef323d914e2a778a5 240 Gene3D G3DSA:3.30.420.180 118 240 2.9E-27 T 01-11-2018 IPR036518 CobE/GbiG C-terminal domain superfamily GO:0009236 AFULGI_00008050 715af569081183cef323d914e2a778a5 240 SUPERFAMILY SSF159664 126 240 4.45E-28 T 01-11-2018 IPR036518 CobE/GbiG C-terminal domain superfamily GO:0009236 AFULGI_00003560 cab679078546c8c9861ac428752c5fb7 56 SUPERFAMILY SSF54862 3 55 8.2E-20 T 01-11-2018 AFULGI_00003560 cab679078546c8c9861ac428752c5fb7 56 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 38 49 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFULGI_00003560 cab679078546c8c9861ac428752c5fb7 56 Gene3D G3DSA:3.30.70.20 29 56 2.4E-9 T 01-11-2018 AFULGI_00003560 cab679078546c8c9861ac428752c5fb7 56 Gene3D G3DSA:3.30.70.20 2 28 3.1E-8 T 01-11-2018 AFULGI_00003560 cab679078546c8c9861ac428752c5fb7 56 Pfam PF12838 4Fe-4S dicluster domain 10 52 1.2E-10 T 01-11-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFULGI_00027010 d0f68fe1dbce8dba69b6b31cb36dbe93 167 TIGRFAM TIGR00372 cas4: CRISPR-associated protein Cas4 11 165 1.1E-26 T 01-11-2018 IPR013343 CRISPR-associated protein Cas4 AFULGI_00027010 d0f68fe1dbce8dba69b6b31cb36dbe93 167 Gene3D G3DSA:3.90.320.10 10 167 1.5E-5 T 01-11-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal AFULGI_00027010 d0f68fe1dbce8dba69b6b31cb36dbe93 167 Pfam PF01930 Domain of unknown function DUF83 11 166 7.7E-54 T 01-11-2018 IPR022765 Dna2/Cas4, domain of unknown function DUF83 AFULGI_00004970 7951f97984037bb4be8ed573051b890a 109 PIRSF PIRSF004952 1 109 3.3E-38 T 01-11-2018 IPR016434 Ribonuclease P, protein component 2 GO:0001682|GO:0004526 AFULGI_00004970 7951f97984037bb4be8ed573051b890a 109 SUPERFAMILY SSF160350 2 108 6.28E-30 T 01-11-2018 IPR038085 Rnp2-like domain superfamily Reactome: R-HSA-6784531 AFULGI_00004970 7951f97984037bb4be8ed573051b890a 109 Gene3D G3DSA:3.30.70.3250 1 109 1.9E-34 T 01-11-2018 IPR038085 Rnp2-like domain superfamily Reactome: R-HSA-6784531 AFULGI_00004970 7951f97984037bb4be8ed573051b890a 109 Hamap MF_00755 Ribonuclease P protein component 2 [rnp2]. 1 109 24.503 T 01-11-2018 IPR002759 Ribonuclease P/MRP protein subunit GO:0004540|GO:0008033 Reactome: R-HSA-6784531 AFULGI_00004970 7951f97984037bb4be8ed573051b890a 109 Pfam PF01900 Rpp14/Pop5 family 13 106 2.7E-18 T 01-11-2018 IPR002759 Ribonuclease P/MRP protein subunit GO:0004540|GO:0008033 Reactome: R-HSA-6784531 AFULGI_00026130 682a4204370f0c65f26931d90e9a35ad 151 SUPERFAMILY SSF54637 2 148 3.26E-50 T 01-11-2018 IPR029069 HotDog domain superfamily AFULGI_00026130 682a4204370f0c65f26931d90e9a35ad 151 Pfam PF01575 MaoC like domain 11 122 1.9E-39 T 01-11-2018 IPR002539 MaoC-like dehydratase domain AFULGI_00026130 682a4204370f0c65f26931d90e9a35ad 151 Gene3D G3DSA:3.10.129.10 1 151 2.3E-55 T 01-11-2018 AFULGI_00016780 2a235db3f0926107db1965ac79fb0f40 194 SUPERFAMILY SSF52540 9 138 1.43E-15 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00016780 2a235db3f0926107db1965ac79fb0f40 194 Pfam PF05707 Zonular occludens toxin (Zot) 68 139 3.1E-8 T 01-11-2018 IPR008900 Zona occludens toxin AFULGI_00016780 2a235db3f0926107db1965ac79fb0f40 194 Gene3D G3DSA:3.40.50.300 6 191 1.0E-34 T 01-11-2018 AFULGI_00019610 e8eb93f3e0f7700623c519e46ef2f30a 131 SUPERFAMILY SSF88723 15 118 8.69E-11 T 01-11-2018 IPR029060 PIN-like domain superfamily AFULGI_00019610 e8eb93f3e0f7700623c519e46ef2f30a 131 Pfam PF01850 PIN domain 15 103 2.9E-10 T 01-11-2018 IPR002716 PIN domain AFULGI_00017600 7fb07431cda59eb45698902732ef9aba 480 Pfam PF01925 Sulfite exporter TauE/SafE 28 296 4.5E-32 T 01-11-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 AFULGI_00018760 3bd0334d64c99305e79af3e757c4a5a1 583 Gene3D G3DSA:2.60.40.10 275 371 1.0E-6 T 01-11-2018 IPR013783 Immunoglobulin-like fold AFULGI_00018760 3bd0334d64c99305e79af3e757c4a5a1 583 SUPERFAMILY SSF49373 289 366 1.2E-5 T 01-11-2018 IPR008964 Invasin/intimin cell-adhesion fragments AFULGI_00020890 2f7052c3faefdfdf22a0d83b032cdb5c 277 Pfam PF01874 ATP:dephospho-CoA triphosphoribosyl transferase 12 270 1.1E-57 T 01-11-2018 IPR002736 Triphosphoribosyl-dephospho-CoA protein GO:0005524|GO:0016310|GO:0046917 MetaCyc: PWY-5796 AFULGI_00020890 2f7052c3faefdfdf22a0d83b032cdb5c 277 Gene3D G3DSA:1.10.4200.10 28 276 2.1E-94 T 01-11-2018 AFULGI_00023480 e9a7e41c2656e1ee3b695984e5d1e9e8 152 Pfam PF06510 Protein of unknown function (DUF1102) 35 148 6.1E-26 T 01-11-2018 IPR009482 Protein of unknown function DUF1102 AFULGI_00022240 9e06f2e7b5bb07bf29e48d592d5c5181 109 Gene3D G3DSA:3.40.1260.10 1 108 4.2E-14 T 01-11-2018 IPR027396 DsrEFH-like AFULGI_00022240 9e06f2e7b5bb07bf29e48d592d5c5181 109 SUPERFAMILY SSF75169 1 83 1.0E-5 T 01-11-2018 IPR027396 DsrEFH-like AFULGI_00014180 f539adc3c6f23d4de3b30fd4913e2c22 264 Pfam PF02593 Domain of unknown function 5 245 8.3E-70 T 01-11-2018 IPR003745 Protein of unknown function DUF166 AFULGI_00001700 f49de678479b2c842e4f69538378d3eb 119 Pfam PF02635 DsrE/DsrF-like family 3 119 2.0E-19 T 01-11-2018 IPR003787 Sulphur relay, DsrE/F-like protein AFULGI_00001700 f49de678479b2c842e4f69538378d3eb 119 Gene3D G3DSA:3.40.1260.10 1 119 5.7E-36 T 01-11-2018 IPR027396 DsrEFH-like AFULGI_00001700 f49de678479b2c842e4f69538378d3eb 119 SUPERFAMILY SSF75169 1 119 4.71E-25 T 01-11-2018 IPR027396 DsrEFH-like AFULGI_00002220 30a58aa43b1568620192dac0b44bb48f 458 Gene3D G3DSA:1.20.1730.10 19 458 3.3E-55 T 01-11-2018 IPR038377 Sodium/glucose symporter superfamily AFULGI_00002220 30a58aa43b1568620192dac0b44bb48f 458 Pfam PF00474 Sodium:solute symporter family 32 347 1.7E-34 T 01-11-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 AFULGI_00026300 1fe75934d68fde0070ac023da7bbb326 129 SUPERFAMILY SSF52980 2 95 8.43E-13 T 01-11-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 AFULGI_00002340 feadc8e6613ea74d7d7e696ea674bc67 378 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 25 349 1.0E-53 T 01-11-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 AFULGI_00002340 feadc8e6613ea74d7d7e696ea674bc67 378 SUPERFAMILY SSF51395 23 375 5.92E-98 T 01-11-2018 AFULGI_00002340 feadc8e6613ea74d7d7e696ea674bc67 378 Gene3D G3DSA:3.20.20.70 23 378 2.0E-112 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFULGI_00003300 4daca1e1a6f25458e1adca1ea3ef96b2 396 TIGRFAM TIGR00261 traB: TraB family protein 1 377 1.3E-197 T 01-11-2018 IPR005230 Pheromone shutdown, TraB, bacterial/archaeal AFULGI_00003300 4daca1e1a6f25458e1adca1ea3ef96b2 396 Pfam PF01963 TraB family 5 220 1.9E-31 T 01-11-2018 IPR002816 Pheromone shutdown, TraB AFULGI_00001510 d22a64da6343127d0a17812673de5546 202 Pfam PF06168 Protein of unknown function (DUF981) 1 186 1.1E-53 T 01-11-2018 IPR009324 Protein of unknown function DUF981 AFULGI_00009490 e0794647c1247c4a6beb08988bc4ecdf 266 Gene3D G3DSA:3.40.50.1820 3 259 1.2E-60 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold AFULGI_00009490 e0794647c1247c4a6beb08988bc4ecdf 266 PRINTS PR00111 Alpha/beta hydrolase fold signature 105 118 3.3E-13 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 AFULGI_00009490 e0794647c1247c4a6beb08988bc4ecdf 266 PRINTS PR00111 Alpha/beta hydrolase fold signature 91 104 3.3E-13 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 AFULGI_00009490 e0794647c1247c4a6beb08988bc4ecdf 266 PRINTS PR00111 Alpha/beta hydrolase fold signature 202 216 3.3E-13 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 AFULGI_00009490 e0794647c1247c4a6beb08988bc4ecdf 266 PRINTS PR00111 Alpha/beta hydrolase fold signature 45 60 3.3E-13 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 AFULGI_00009490 e0794647c1247c4a6beb08988bc4ecdf 266 SUPERFAMILY SSF53474 6 256 2.81E-62 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold AFULGI_00009490 e0794647c1247c4a6beb08988bc4ecdf 266 Pfam PF00561 alpha/beta hydrolase fold 20 244 4.4E-27 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 AFULGI_00006280 62105531e0f12044b18893fe8d21ef66 162 Pfam PF03750 Csm2 Type III-A 56 160 3.8E-18 T 01-11-2018 IPR010149 CRISPR-associated protein, Csm2 Type III-A AFULGI_00006280 62105531e0f12044b18893fe8d21ef66 162 TIGRFAM TIGR01870 cas_TM1810_Csm2: CRISPR type III-A/MTUBE-associated protein Csm2 75 159 9.7E-18 T 01-11-2018 IPR010149 CRISPR-associated protein, Csm2 Type III-A AFULGI_00019060 e09a7a0619869c7dc3b917aec45ebc45 151 SUPERFAMILY SSF51306 28 131 1.28E-9 T 01-11-2018 IPR036286 LexA/Signal peptidase-like superfamily AFULGI_00019060 e09a7a0619869c7dc3b917aec45ebc45 151 TIGRFAM TIGR02228 sigpep_I_arch: signal peptidase I 7 144 2.8E-24 T 01-11-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 AFULGI_00019060 e09a7a0619869c7dc3b917aec45ebc45 151 Pfam PF00717 Peptidase S24-like 30 95 4.9E-7 T 01-11-2018 IPR015927 Peptidase S24/S26A/S26B/S26C AFULGI_00017050 51cc037155fc5e76bd10edf53410e817 249 Gene3D G3DSA:3.60.21.10 1 202 5.4E-13 T 01-11-2018 IPR029052 Metallo-dependent phosphatase-like AFULGI_00017050 51cc037155fc5e76bd10edf53410e817 249 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 146 2.7E-11 T 01-11-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 AFULGI_00017050 51cc037155fc5e76bd10edf53410e817 249 SUPERFAMILY SSF56300 1 201 3.49E-20 T 01-11-2018 AFULGI_00024880 b593356fdf954c30690e812825621cff 72 Pfam PF01850 PIN domain 11 67 9.3E-17 T 01-11-2018 IPR002716 PIN domain AFULGI_00024880 b593356fdf954c30690e812825621cff 72 SUPERFAMILY SSF88723 5 66 1.85E-10 T 01-11-2018 IPR029060 PIN-like domain superfamily AFULGI_00024880 b593356fdf954c30690e812825621cff 72 Gene3D G3DSA:3.40.50.1010 2 70 6.6E-8 T 01-11-2018 AFULGI_00006940 98a1a65799c90ca6780f95c5a10c0518 129 Pfam PF04138 GtrA-like protein 9 128 2.8E-24 T 01-11-2018 IPR007267 GtrA-like protein GO:0000271|GO:0016021 AFULGI_00025410 7536ff313d2cdb8b072ee32e45ad2f13 349 Pfam PF03773 Predicted permease 8 345 7.9E-92 T 01-11-2018 IPR005524 Predicted permease DUF318 AFULGI_00002950 8dce9b103e55f0d5782734e946fe308b 120 Gene3D G3DSA:1.20.120.330 1 120 4.1E-33 T 01-11-2018 AFULGI_00002950 8dce9b103e55f0d5782734e946fe308b 120 Pfam PF05168 HEPN domain 2 114 1.3E-25 T 01-11-2018 IPR007842 HEPN domain AFULGI_00016060 0a4151d37db4fa29be17948a954381f9 375 Pfam PF07758 Protein of unknown function (DUF1614) 159 286 1.7E-14 T 01-11-2018 IPR011672 Protein of unknown function DUF1614 AFULGI_00016200 d570cc50fe3e7891f0274de19acc6add 75 Pfam PF10049 Protein of unknown function (DUF2283) 2 49 1.9E-13 T 01-11-2018 IPR019270 Protein of unknown function DUF2283 AFULGI_00001240 1075e95f9aa575f7b772e3d9db4d009f 202 Pfam PF01402 Ribbon-helix-helix protein, copG family 6 43 1.6E-7 T 01-11-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 AFULGI_00009770 d95dc25ef53b773aa1a64dffe83189e7 332 Pfam PF02653 Branched-chain amino acid transport system / permease component 47 322 8.2E-40 T 01-11-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 AFULGI_00025770 6dc17e6c83c6d6c6a01f9a4e19ca9775 69 TIGRFAM TIGR00304 TIGR00304: TIGR00304 family protein 1 66 4.1E-23 T 01-11-2018 IPR002849 Protein of unknown function DUF131 AFULGI_00025770 6dc17e6c83c6d6c6a01f9a4e19ca9775 69 Pfam PF01998 Protein of unknown function DUF131 25 67 2.3E-14 T 01-11-2018 IPR002849 Protein of unknown function DUF131 AFULGI_00026390 9abc76f6094f44091d1d3279cb51d278 75 SMART SM00966 3 50 1.4E-11 T 01-11-2018 IPR007159 SpoVT-AbrB domain GO:0003677 AFULGI_00026390 9abc76f6094f44091d1d3279cb51d278 75 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 3 49 1.7E-11 T 01-11-2018 IPR007159 SpoVT-AbrB domain GO:0003677 AFULGI_00026390 9abc76f6094f44091d1d3279cb51d278 75 SUPERFAMILY SSF89447 2 43 5.93E-10 T 01-11-2018 IPR037914 SpoVT-AbrB domain superfamily AFULGI_00026390 9abc76f6094f44091d1d3279cb51d278 75 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 2 37 1.3E-14 T 01-11-2018 IPR007159 SpoVT-AbrB domain GO:0003677 AFULGI_00026390 9abc76f6094f44091d1d3279cb51d278 75 Gene3D G3DSA:2.10.260.10 2 44 2.1E-14 T 01-11-2018 AFULGI_00019450 672be0b81fecd6f143b3866746d17641 150 Pfam PF06695 Putative small multi-drug export protein 18 138 7.0E-42 T 01-11-2018 IPR009577 Putative small multi-drug export AFULGI_00005350 f0a194a7226bc0defbe581d18e7d0f5e 59 Pfam PF04135 Nucleolar RNA-binding protein, Nop10p family 1 51 4.7E-25 T 01-11-2018 IPR007264 H/ACA ribonucleoprotein complex, subunit Nop10 GO:0001522|GO:0030515|GO:0042254 Reactome: R-HSA-6790901 AFULGI_00005350 f0a194a7226bc0defbe581d18e7d0f5e 59 SUPERFAMILY SSF144210 4 54 8.5E-21 T 01-11-2018 IPR036756 H/ACA ribonucleoprotein complex, subunit Nop10 superfamily GO:0001522|GO:0030515|GO:0042254 Reactome: R-HSA-6790901 AFULGI_00005350 f0a194a7226bc0defbe581d18e7d0f5e 59 Hamap MF_00803 Ribosome biogenesis protein Nop10 [nop10]. 3 53 19.071 T 01-11-2018 IPR023532 H/ACA ribonucleoprotein complex subunit Nop10 , archaeal-type GO:0001522|GO:0030515|GO:0042254 AFULGI_00005350 f0a194a7226bc0defbe581d18e7d0f5e 59 Gene3D G3DSA:2.20.28.40 1 56 6.6E-26 T 01-11-2018 IPR036756 H/ACA ribonucleoprotein complex, subunit Nop10 superfamily GO:0001522|GO:0030515|GO:0042254 Reactome: R-HSA-6790901 AFULGI_00012040 330c81d39aba28843339d84188109381 146 Gene3D G3DSA:3.10.690.10 11 139 1.9E-47 T 01-11-2018 IPR036104 Bifunctional nuclease superfamily GO:0004518 AFULGI_00012040 330c81d39aba28843339d84188109381 146 SUPERFAMILY SSF103256 17 131 9.02E-45 T 01-11-2018 IPR036104 Bifunctional nuclease superfamily GO:0004518 AFULGI_00012040 330c81d39aba28843339d84188109381 146 Pfam PF02577 Bifunctional nuclease 18 131 4.1E-45 T 01-11-2018 IPR003729 Bifunctional nuclease domain GO:0004518 AFULGI_00017480 90aeb12a02aba0e9a4bbaf1a0e89bf21 353 Pfam PF05559 Protein of unknown function (DUF763) 5 308 2.9E-119 T 01-11-2018 IPR008482 Protein of unknown function DUF763 AFULGI_00009570 eed0bfdeefe8ac7d236503ae3e64ea23 64 Pfam PF09889 Uncharacterized protein containing a Zn-ribbon (DUF2116) 6 62 1.6E-27 T 01-11-2018 IPR019216 Protein of unknown function DUF2116, Zn-ribbon AFULGI_00009570 eed0bfdeefe8ac7d236503ae3e64ea23 64 PIRSF PIRSF004990 1 62 2.4E-37 T 01-11-2018 IPR019216 Protein of unknown function DUF2116, Zn-ribbon AFULGI_00023500 e1c6fc797752f311b02ea47e96c07bfc 196 Pfam PF06510 Protein of unknown function (DUF1102) 38 183 8.9E-58 T 01-11-2018 IPR009482 Protein of unknown function DUF1102 AFULGI_00006860 598dfc45997070f4ef099f17767e621c 158 SUPERFAMILY SSF88723 1 118 1.4E-10 T 01-11-2018 IPR029060 PIN-like domain superfamily AFULGI_00006860 598dfc45997070f4ef099f17767e621c 158 Pfam PF10130 PIN domain 5 150 3.8E-42 T 01-11-2018 IPR002716 PIN domain AFULGI_00006860 598dfc45997070f4ef099f17767e621c 158 Gene3D G3DSA:3.40.50.1010 2 120 1.7E-6 T 01-11-2018 AFULGI_00003540 0fd14b150d6d2b73684c94013826d61f 186 Gene3D G3DSA:3.40.50.300 33 186 7.1E-6 T 01-11-2018 AFULGI_00003610 3534e2c42dc0aba90216b7f0238e69ec 232 Pfam PF07758 Protein of unknown function (DUF1614) 54 226 4.0E-50 T 01-11-2018 IPR011672 Protein of unknown function DUF1614 AFULGI_00007180 5ca1bf9cf3382ae4cfda5cad19939c51 152 Pfam PF08905 Domain of unknown function (DUF1850) 44 127 2.8E-17 T 01-11-2018 IPR015001 Protein of unknown function DUF1850 AFULGI_00007180 5ca1bf9cf3382ae4cfda5cad19939c51 152 PIRSF PIRSF008455 1 152 1.1E-68 T 01-11-2018 IPR014451 Uncharacterised conserved protein UCP008455 AFULGI_00000740 f4ec08942be980782def202d8fe7d62a 431 Pfam PF01629 Domain of unknown function DUF22 149 254 9.1E-39 T 01-11-2018 IPR002572 Domain of unknown function DUF22 AFULGI_00000740 f4ec08942be980782def202d8fe7d62a 431 Pfam PF01629 Domain of unknown function DUF22 2 109 2.8E-32 T 01-11-2018 IPR002572 Domain of unknown function DUF22 AFULGI_00000740 f4ec08942be980782def202d8fe7d62a 431 Pfam PF01629 Domain of unknown function DUF22 288 393 1.4E-34 T 01-11-2018 IPR002572 Domain of unknown function DUF22 AFULGI_00018480 503443138489bbae3e2096f743102740 103 Pfam PF14018 Domain of unknown function (DUF4234) 5 60 9.8E-10 T 01-11-2018 IPR025328 Domain of unknown function DUF4234 AFULGI_00022260 3eb42f54d9862d0721937e722b9e3f2e 191 PIRSF PIRSF015877 1 191 6.5E-66 T 01-11-2018 IPR012041 Uncharacterised conserved protein UCP015877, zinc finger-containing AFULGI_00021370 2dc5aceb3411b1b65b4aac004ad3f6c6 180 Gene3D G3DSA:3.90.320.10 1 180 2.2E-15 T 01-11-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal AFULGI_00021370 2dc5aceb3411b1b65b4aac004ad3f6c6 180 Pfam PF01930 Domain of unknown function DUF83 3 180 2.1E-34 T 01-11-2018 IPR022765 Dna2/Cas4, domain of unknown function DUF83 AFULGI_00021370 2dc5aceb3411b1b65b4aac004ad3f6c6 180 TIGRFAM TIGR00372 cas4: CRISPR-associated protein Cas4 1 180 9.3E-53 T 01-11-2018 IPR013343 CRISPR-associated protein Cas4 AFULGI_00017670 30b933a949a224b66f50659b73dd172f 88 Gene3D G3DSA:3.30.1490.340 1 88 5.4E-45 T 01-11-2018 AFULGI_00020810 0d5270db0568487f9afab1053b2f1ab1 401 Pfam PF00361 Proton-conducting membrane transporter 88 350 9.8E-21 T 01-11-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFULGI_00004080 f3b800fbb89fdf36c0c8fb0675cccd29 288 Gene3D G3DSA:1.10.357.140 14 172 5.5E-17 T 01-11-2018 AFULGI_00004080 f3b800fbb89fdf36c0c8fb0675cccd29 288 Hamap MF_01286 Digeranylgeranylglyceryl phosphate synthase. 8 288 19.915 T 01-11-2018 IPR023547 Digeranylgeranylglyceryl phosphate synthase GO:0000287|GO:0005886|GO:0008654|GO:0047295 KEGG: 00564+2.5.1.42|MetaCyc: PWY-6349 AFULGI_00004080 f3b800fbb89fdf36c0c8fb0675cccd29 288 Pfam PF01040 UbiA prenyltransferase family 27 268 1.3E-40 T 01-11-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 AFULGI_00012360 010b7ec563ba6b00783d7d0cf2844c95 297 Pfam PF12679 ABC-2 family transporter protein 4 297 1.3E-65 T 01-11-2018 IPR032688 ABC-2 family transporter protein GO:0055085 AFULGI_00020090 5280545b2187a1d1eed29cda2c8041f4 193 Pfam PF01364 Peptidase family C25 57 170 2.2E-6 T 01-11-2018 IPR001769 Gingipain GO:0006508|GO:0008234 AFULGI_00018770 1252cf353e9486182d55ec854209a449 120 Pfam PF09946 Predicted membrane protein (DUF2178) 9 107 1.9E-27 T 01-11-2018 IPR019235 Protein of unknown function DUF2178, transmembrane AFULGI_00009340 0a50b1af8511df22b8e3198e5084b9c9 337 PIRSF PIRSF009433 1 337 4.9E-135 T 01-11-2018 IPR009927 Protein of unknown function DUF1464 AFULGI_00009340 0a50b1af8511df22b8e3198e5084b9c9 337 Pfam PF07318 Protein of unknown function (DUF1464) 5 321 2.6E-127 T 01-11-2018 IPR009927 Protein of unknown function DUF1464 AFULGI_00011820 8a95dc74b9716a77ca63d4bca0859c4c 144 SUPERFAMILY SSF88723 1 138 4.49E-17 T 01-11-2018 IPR029060 PIN-like domain superfamily AFULGI_00011820 8a95dc74b9716a77ca63d4bca0859c4c 144 Pfam PF01850 PIN domain 2 122 7.0E-11 T 01-11-2018 IPR002716 PIN domain AFULGI_00011820 8a95dc74b9716a77ca63d4bca0859c4c 144 Gene3D G3DSA:3.40.50.1010 1 126 1.7E-9 T 01-11-2018 AFULGI_00000100 5c3058ecf43847b6c17d2b89cea0815b 416 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 204 413 2.7E-17 T 01-11-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 AFULGI_00000100 5c3058ecf43847b6c17d2b89cea0815b 416 Gene3D G3DSA:3.20.20.210 4 413 3.6E-45 T 01-11-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 AFULGI_00000100 5c3058ecf43847b6c17d2b89cea0815b 416 SUPERFAMILY SSF51726 7 416 6.63E-41 T 01-11-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 AFULGI_00014860 b988cd953a9c0b707e13ed09ce4de5e6 134 Pfam PF02662 Methyl-viologen-reducing hydrogenase, delta subunit 3 125 9.9E-49 T 01-11-2018 IPR003813 F420-non-reducing hydrogenase iron-sulfur subunit D GO:0055114 AFULGI_00015070 b0f90be3e1502e84d04298d1b1c110f5 162 SUPERFAMILY SSF64288 2 159 7.85E-45 T 01-11-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily AFULGI_00015070 b0f90be3e1502e84d04298d1b1c110f5 162 Gene3D G3DSA:3.40.1410.10 1 162 1.3E-56 T 01-11-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily AFULGI_00015070 b0f90be3e1502e84d04298d1b1c110f5 162 Pfam PF01947 Protein of unknown function (DUF98) 9 160 5.2E-42 T 01-11-2018 IPR002800 Chorismate pyruvate-lyase Rv2949c-like AFULGI_00001190 3b59efcf543350e07111d5d333e77bf5 439 Pfam PF01629 Domain of unknown function DUF22 287 392 1.8E-41 T 01-11-2018 IPR002572 Domain of unknown function DUF22 AFULGI_00001190 3b59efcf543350e07111d5d333e77bf5 439 Pfam PF01629 Domain of unknown function DUF22 150 255 1.3E-43 T 01-11-2018 IPR002572 Domain of unknown function DUF22 AFULGI_00001190 3b59efcf543350e07111d5d333e77bf5 439 Pfam PF01629 Domain of unknown function DUF22 3 110 2.8E-39 T 01-11-2018 IPR002572 Domain of unknown function DUF22 AFULGI_00020190 109a5da61a8f625397736fcb60c07e0c 336 Gene3D G3DSA:1.10.3720.10 90 330 8.5E-16 T 01-11-2018 IPR035906 MetI-like superfamily AFULGI_00020190 109a5da61a8f625397736fcb60c07e0c 336 SUPERFAMILY SSF161098 95 323 2.75E-8 T 01-11-2018 IPR035906 MetI-like superfamily AFULGI_00020190 109a5da61a8f625397736fcb60c07e0c 336 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 117 336 1.1E-47 T 01-11-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFULGI_00022830 fcd994aab3d351428e290bb7ff4e1bdc 244 Pfam PF01925 Sulfite exporter TauE/SafE 10 232 1.1E-16 T 01-11-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 AFULGI_00013980 f8dc8c3ff8f64d513f8b322cdff5cf00 138 Pfam PF02310 B12 binding domain 5 118 1.7E-22 T 01-11-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 AFULGI_00013980 f8dc8c3ff8f64d513f8b322cdff5cf00 138 Gene3D G3DSA:3.40.50.280 1 138 6.8E-54 T 01-11-2018 AFULGI_00013980 f8dc8c3ff8f64d513f8b322cdff5cf00 138 SUPERFAMILY SSF52242 3 133 3.14E-47 T 01-11-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 AFULGI_00013980 f8dc8c3ff8f64d513f8b322cdff5cf00 138 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 3 135 4.7E-52 T 01-11-2018 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 AFULGI_00001210 fcc462efbf377356cd1df7fc61aa9e67 289 Pfam PF01925 Sulfite exporter TauE/SafE 10 276 4.4E-36 T 01-11-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 AFULGI_00016240 144e857271cb18d84860a242ac39d5bd 80 SUPERFAMILY SSF89447 5 59 1.44E-7 T 01-11-2018 IPR037914 SpoVT-AbrB domain superfamily AFULGI_00014060 76af8e65b719780c249ff3aa56cb5d68 137 Pfam PF10865 Domain of unknown function (DUF2703) 3 118 2.5E-37 T 01-11-2018 IPR021219 Protein of unknown function DUF2703 AFULGI_00005920 f1613e59812d32e307d35fe52b8128c0 243 SUPERFAMILY SSF48537 22 95 3.92E-6 T 01-11-2018 IPR008947 Phospholipase C/P1 nuclease domain superfamily GO:0016788 AFULGI_00004940 96a4dfed289b86c753b509e839147bd4 128 Pfam PF03692 Putative zinc- or iron-chelating domain 17 99 4.5E-12 T 01-11-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein AFULGI_00006980 d1b59bdb5626ddc321fb31232e042ca7 53 SUPERFAMILY SSF47598 3 44 7.56E-5 T 01-11-2018 IPR010985 Ribbon-helix-helix GO:0006355 AFULGI_00002830 be9e0045e184c84ad01398942fc48d4a 252 Pfam PF01061 ABC-2 type transporter 11 212 3.2E-22 T 01-11-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 AFULGI_00016530 9b87e6741894573dfb520ad18b07a8b1 91 Pfam PF03683 Uncharacterised protein family (UPF0175) 20 86 3.4E-16 T 01-11-2018 IPR005368 Uncharacterised protein family UPF0175 AFULGI_00023070 b73b44b503f5e6039c09366b339ae0a8 396 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 5 381 1.6E-51 T 01-11-2018 IPR002823 Protein of unknown function DUF112, transmembrane AFULGI_00014850 c9b93fd78d92e58deeaa1df60eef0de1 293 Gene3D G3DSA:3.40.50.700 2 174 1.3E-31 T 01-11-2018 IPR037024 [NiFe]-hydrogenase, small subunit, N-terminal domain superfamily AFULGI_00014850 c9b93fd78d92e58deeaa1df60eef0de1 293 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 12 156 5.6E-26 T 01-11-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFULGI_00014850 c9b93fd78d92e58deeaa1df60eef0de1 293 SUPERFAMILY SSF56770 3 231 8.77E-47 T 01-11-2018 AFULGI_00026890 f54723138528ce030160daa45ed2597e 406 Pfam PF01882 Protein of unknown function DUF58 186 271 1.0E-26 T 01-11-2018 IPR002881 Domain of unknown function DUF58 AFULGI_00008900 06a66683bed95b775b2ab606ea7e4310 221 Pfam PF04967 HTH DNA binding domain 163 215 1.7E-21 T 01-11-2018 IPR007050 Bacterioopsin activator-type, HTH domain AFULGI_00017830 3e430fe0960286b58a1344c622e6b3cb 97 ProSitePatterns PS01171 Ribosomal protein L21e signature. 37 62 - T 01-11-2018 IPR018259 Ribosomal protein L21e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00017830 3e430fe0960286b58a1344c622e6b3cb 97 Pfam PF01157 Ribosomal protein L21e 4 95 3.0E-30 T 01-11-2018 IPR001147 Ribosomal protein L21e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00017830 3e430fe0960286b58a1344c622e6b3cb 97 SUPERFAMILY SSF50104 4 95 1.62E-30 T 01-11-2018 IPR008991 Translation protein SH3-like domain superfamily AFULGI_00017830 3e430fe0960286b58a1344c622e6b3cb 97 Gene3D G3DSA:2.30.30.70 3 96 1.0E-34 T 01-11-2018 IPR036948 Ribosomal protein L21 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFULGI_00017830 3e430fe0960286b58a1344c622e6b3cb 97 Hamap MF_00369 50S ribosomal protein L21e [rpl21e]. 3 96 29.18 T 01-11-2018 IPR022856 Ribosomal protein L21e, archaeal AFULGI_00000730 5e9fd8505e78576ff69d12d568fb2485 246 SMART SM00460 167 227 2.6E-11 T 01-11-2018 IPR002931 Transglutaminase-like AFULGI_00000730 5e9fd8505e78576ff69d12d568fb2485 246 SUPERFAMILY SSF54001 121 218 1.32E-7 T 01-11-2018 IPR038765 Papain-like cysteine peptidase superfamily AFULGI_00000730 5e9fd8505e78576ff69d12d568fb2485 246 Pfam PF01841 Transglutaminase-like superfamily 156 214 3.5E-7 T 01-11-2018 IPR002931 Transglutaminase-like AFULGI_00021020 80f138ebe9916a47b97ae1e075c02cfd 199 Pfam PF04967 HTH DNA binding domain 141 193 1.7E-18 T 01-11-2018 IPR007050 Bacterioopsin activator-type, HTH domain AFULGI_00014970 088b4d2e1c11ba860e111c9017681835 145 Pfam PF01850 PIN domain 1 116 1.4E-18 T 01-11-2018 IPR002716 PIN domain AFULGI_00014970 088b4d2e1c11ba860e111c9017681835 145 Gene3D G3DSA:3.40.50.1010 1 118 6.8E-11 T 01-11-2018 AFULGI_00014970 088b4d2e1c11ba860e111c9017681835 145 SUPERFAMILY SSF88723 1 117 2.55E-15 T 01-11-2018 IPR029060 PIN-like domain superfamily AFULGI_00012680 17a850386ad3bb76ceab23ca55d7737e 206 Gene3D G3DSA:1.10.1760.20 2 200 1.9E-40 T 01-11-2018 AFULGI_00012680 17a850386ad3bb76ceab23ca55d7737e 206 Pfam PF02632 BioY family 28 195 1.1E-29 T 01-11-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 AFULGI_00007630 3e08b3d4a952b355304cc6387d37fe37 124 Gene3D G3DSA:1.20.1300.10 11 121 1.0E-14 T 01-11-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFULGI_00007630 3e08b3d4a952b355304cc6387d37fe37 124 SUPERFAMILY SSF81343 16 119 9.16E-18 T 01-11-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFULGI_00007630 3e08b3d4a952b355304cc6387d37fe37 124 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 14 112 9.2E-12 T 01-11-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFULGI_00012590 befb1fe0434b86500b8c92fb5f9b794d 109 TIGRFAM TIGR02926 AhaH: ATP synthase archaeal, H subunit 7 91 1.9E-26 T 01-11-2018 IPR014275 ATPase, A1A0, subunit H AFULGI_00010510 99f6fabffe75f2311488016ad480d6a6 238 Pfam PF02653 Branched-chain amino acid transport system / permease component 3 235 1.9E-13 T 01-11-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 AFULGI_00006110 2e137d26854964fb18801adc83cd987f 452 Pfam PF10117 McrBC 5-methylcytosine restriction system component 67 392 3.5E-68 T 01-11-2018 IPR019292 5-methylcytosine restriction system component AFULGI_00017640 a3c47dc30b782f35e917ed3f6f74a11d 250 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 150 178 6.8E-30 T 01-11-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 AFULGI_00017640 a3c47dc30b782f35e917ed3f6f74a11d 250 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 84 102 6.8E-30 T 01-11-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 AFULGI_00017640 a3c47dc30b782f35e917ed3f6f74a11d 250 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 102 128 6.8E-30 T 01-11-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 AFULGI_00017640 a3c47dc30b782f35e917ed3f6f74a11d 250 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 11 38 6.8E-30 T 01-11-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 AFULGI_00017640 a3c47dc30b782f35e917ed3f6f74a11d 250 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 12 223 5.7E-58 T 01-11-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 AFULGI_00017640 a3c47dc30b782f35e917ed3f6f74a11d 250 Pfam PF00902 Sec-independent protein translocase protein (TatC) 14 214 2.0E-40 T 01-11-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 AFULGI_00005330 244388d6fbb29d41359c99c6855838dc 225 Pfam PF07786 Protein of unknown function (DUF1624) 2 207 3.9E-58 T 01-11-2018 IPR012429 Domain of unknown function DUF1624 Reactome: R-HSA-2024096|Reactome: R-HSA-2206291|Reactome: R-HSA-6798695 AFULGI_00015420 5e0c5aafb82f9eeb2a5cf26e88b394ca 500 Pfam PF09959 Uncharacterized protein conserved in archaea (DUF2193) 4 500 5.5E-280 T 01-11-2018 IPR018694 Protein of unknown function DUF2193 AFULGI_00011390 caf694760d378b8948a35f0671e3d064 269 PIRSF PIRSF026802 1 267 2.6E-122 T 01-11-2018 IPR007381 Chemotaxis signal transduction system protein F AFULGI_00011390 caf694760d378b8948a35f0671e3d064 269 Pfam PF04283 Chemotaxis signal transduction system protein F from archaea 19 187 8.3E-19 T 01-11-2018 IPR007381 Chemotaxis signal transduction system protein F AFULGI_00022790 784962c82d41ee14dc725e0f891a7516 401 SUPERFAMILY SSF103473 9 400 1.06E-66 T 01-11-2018 IPR036259 MFS transporter superfamily AFULGI_00022790 784962c82d41ee14dc725e0f891a7516 401 Gene3D G3DSA:1.20.1250.20 9 401 1.5E-63 T 01-11-2018 AFULGI_00022790 784962c82d41ee14dc725e0f891a7516 401 Pfam PF07690 Major Facilitator Superfamily 27 354 1.0E-39 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFULGI_00017380 e4bb74424f3e5c7d21d8967ba77e7846 216 TIGRFAM TIGR04126 PGF_CTERM: PGF-CTERM archaeal protein-sorting signal 190 213 8.3E-7 T 01-11-2018 IPR026371 PGF-CTERM archaeal protein-sorting signal AFULGI_00016020 f0fc4ddf58d934a45536d0902b830b06 547 Pfam PF00482 Type II secretion system (T2SS), protein F 343 465 1.1E-7 T 01-11-2018 IPR018076 Type II secretion system F domain AFULGI_00016020 f0fc4ddf58d934a45536d0902b830b06 547 Pfam PF00482 Type II secretion system (T2SS), protein F 113 236 1.4E-11 T 01-11-2018 IPR018076 Type II secretion system F domain AFULGI_00024400 9551ea757a264cfb7188ca861802b2eb 136 Gene3D G3DSA:1.20.120.580 1 136 3.2E-6 T 01-11-2018 IPR037038 Bsu32300-like superfamily AFULGI_00024400 9551ea757a264cfb7188ca861802b2eb 136 Pfam PF01934 Protein of unknown function DUF86 28 127 2.0E-18 T 01-11-2018 IPR008201 Protein of unknown function DUF86 AFULGI_00001490 c18d26e7352794ad8397aeb6b539a670 102 Pfam PF09851 Short C-terminal domain 73 99 3.0E-12 T 01-11-2018 IPR018649 SHOCT domain AFULGI_00023090 58e946f9d2b1b781159110625d3431ab 184 Pfam PF14329 Domain of unknown function (DUF4386) 38 90 1.2E-6 T 01-11-2018 IPR025495 Protein of unknown function DUF4386 AFULGI_00023090 58e946f9d2b1b781159110625d3431ab 184 Pfam PF14329 Domain of unknown function (DUF4386) 88 174 1.5E-16 T 01-11-2018 IPR025495 Protein of unknown function DUF4386 AFULGI_00007870 bc8faabf52eaeea084e3c4edd9113033 590 SUPERFAMILY SSF54211 33 223 1.63E-25 T 01-11-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFULGI_00007870 bc8faabf52eaeea084e3c4edd9113033 590 Gene3D G3DSA:3.30.230.10 20 233 2.5E-26 T 01-11-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AFULGI_00007870 bc8faabf52eaeea084e3c4edd9113033 590 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 41 171 7.3E-13 T 01-11-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 AFULGI_00007870 bc8faabf52eaeea084e3c4edd9113033 590 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 104 123 2.8E-7 T 01-11-2018 AFULGI_00007870 bc8faabf52eaeea084e3c4edd9113033 590 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 134 153 2.8E-7 T 01-11-2018 AFULGI_00007870 bc8faabf52eaeea084e3c4edd9113033 590 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 157 175 2.8E-7 T 01-11-2018 AFULGI_00004110 823f4fea964798656cf6baa872c77bac 216 SUPERFAMILY SSF56399 35 206 2.53E-51 T 01-11-2018 AFULGI_00004110 823f4fea964798656cf6baa872c77bac 216 Pfam PF01885 RNA 2'-phosphotransferase, Tpt1 / KptA family 34 195 1.1E-29 T 01-11-2018 IPR002745 Phosphotransferase KptA/Tpt1 GO:0006388|GO:0016772 AFULGI_00004110 823f4fea964798656cf6baa872c77bac 216 Gene3D G3DSA:1.10.10.970 33 103 2.1E-24 T 01-11-2018 AFULGI_00004110 823f4fea964798656cf6baa872c77bac 216 Hamap MF_00299 Probable RNA 2'-phosphotransferase [kptA]. 32 204 34.468 T 01-11-2018 IPR022928 RNA 2'-phosphotransferase KptA, putative GO:0016773 AFULGI_00004110 823f4fea964798656cf6baa872c77bac 216 Gene3D G3DSA:3.20.170.30 123 212 9.8E-23 T 01-11-2018 AFULGI_00023260 b273cafa5babc903e43304ed3994b2b1 344 Pfam PF04123 Domain of unknown function (DUF373) 4 334 3.8E-119 T 01-11-2018 IPR007254 Protein of unknown function DUF373 AFULGI_00003530 7627fa340e65c8120ea0b31518dc07b8 251 Gene3D G3DSA:3.40.50.300 2 233 5.0E-13 T 01-11-2018 AFULGI_00006990 1c490d551d5de367cb92811bae268912 297 Pfam PF00535 Glycosyl transferase family 2 4 166 9.2E-27 T 01-11-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 AFULGI_00006990 1c490d551d5de367cb92811bae268912 297 SUPERFAMILY SSF53448 1 257 1.41E-39 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFULGI_00006990 1c490d551d5de367cb92811bae268912 297 Gene3D G3DSA:3.90.550.10 1 222 8.7E-38 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFULGI_00006540 c43db234b5b842164d2afbb825284754 384 SUPERFAMILY SSF53187 6 381 1.31E-34 T 01-11-2018 AFULGI_00006540 c43db234b5b842164d2afbb825284754 384 Pfam PF04389 Peptidase family M28 207 377 3.9E-17 T 01-11-2018 IPR007484 Peptidase M28 AFULGI_00009990 132ae048cc8f119f879feb78a6521add 112 SUPERFAMILY SSF75169 1 112 1.67E-30 T 01-11-2018 IPR027396 DsrEFH-like AFULGI_00009990 132ae048cc8f119f879feb78a6521add 112 Gene3D G3DSA:3.40.1260.10 1 112 6.5E-34 T 01-11-2018 IPR027396 DsrEFH-like AFULGI_00009990 132ae048cc8f119f879feb78a6521add 112 Pfam PF02635 DsrE/DsrF-like family 2 112 1.7E-17 T 01-11-2018 IPR003787 Sulphur relay, DsrE/F-like protein AFULGI_00008520 eafa01a24aa1cfbb1b0a3bdad2022da9 289 Pfam PF01040 UbiA prenyltransferase family 24 257 1.8E-15 T 01-11-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 AFULGI_00012930 c45b4cb7d69b315fce93a267969663af 122 Pfam PF09999 Uncharacterized protein conserved in archaea (DUF2240) 1 116 7.1E-27 T 01-11-2018 IPR018716 Protein of unknown function DUF2240 AFULGI_00005490 f3378ecc1d0401e90ca3e79ef899903b 228 SUPERFAMILY SSF90257 94 205 5.75E-5 T 01-11-2018 AFULGI_00023960 53611ac61b72d49e2dc8abcff86bb0d8 290 Pfam PF02596 Uncharacterised ArCR, COG2043 41 247 7.3E-50 T 01-11-2018 IPR003748 Protein of unknown function DUF169 AFULGI_00020720 c16ad24c570de6be914d47de26eb3cd8 478 Gene3D G3DSA:2.60.40.10 345 449 5.1E-7 T 01-11-2018 IPR013783 Immunoglobulin-like fold AFULGI_00020720 c16ad24c570de6be914d47de26eb3cd8 478 Pfam PF07705 CARDB 351 427 7.1E-6 T 01-11-2018 IPR011635 CARDB domain AFULGI_00007880 315939d73ed0c576cb839dae2c259ab2 403 Pfam PF01940 Integral membrane protein DUF92 178 386 1.1E-47 T 01-11-2018 IPR002794 Protein of unknown function DUF92, TMEM19 GO:0016021 AFULGI_00007880 315939d73ed0c576cb839dae2c259ab2 403 TIGRFAM TIGR00297 TIGR00297: TIGR00297 family protein 169 401 3.6E-101 T 01-11-2018 IPR002794 Protein of unknown function DUF92, TMEM19 GO:0016021 AFULGI_00015120 4d7938b869806f12179967ee3e9a0d05 133 ProDom PD064925 ATP-BINDING ABC NUCLEOTIDE-BINDING MEMBRANE TRANSPORTER IRON TRANSPORTER COMPOUND ATPASE III 20 87 3.0E-25 T 01-11-2018 IPR020322 Uncharacterised domain MJ0874 AFULGI_00002850 8856f9952ef9cf45ff41a268f54345e3 311 SUPERFAMILY SSF64182 3 310 3.14E-25 T 01-11-2018 IPR038763 DHH phosphoesterase superfamily AFULGI_00010820 df8083be08b2b45a2cebb4dd75520d20 296 Pfam PF02653 Branched-chain amino acid transport system / permease component 11 285 1.6E-37 T 01-11-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 AFULGI_00014040 9fe71dc156926ebee555ad272762f3c2 178 Pfam PF01988 VIT family 81 169 7.1E-11 T 01-11-2018 IPR008217 Ccc1 family AFULGI_00014040 9fe71dc156926ebee555ad272762f3c2 178 TIGRFAM TIGR00267 TIGR00267: TIGR00267 family protein 3 174 5.5E-80 T 01-11-2018 IPR006682 Conserved hypothetical protein CHP00267 AFULGI_00017990 b831585ff3fdc5951de5b25f59958fac 235 Pfam PF04254 Protein of unknown function (DUF432) 56 178 1.9E-48 T 01-11-2018 IPR007366 Protein of unknown function DUF432 AFULGI_00017990 b831585ff3fdc5951de5b25f59958fac 235 PIRSF PIRSF019202 1 235 7.1E-100 T 01-11-2018 IPR007366 Protein of unknown function DUF432 AFULGI_00014870 aa886fbbabce3a65c984e995c17d26f6 292 Pfam PF02754 Cysteine-rich domain 145 236 9.2E-20 T 01-11-2018 IPR004017 Cysteine-rich domain AFULGI_00014870 aa886fbbabce3a65c984e995c17d26f6 292 Pfam PF02754 Cysteine-rich domain 3 85 1.4E-11 T 01-11-2018 IPR004017 Cysteine-rich domain AFULGI_00004220 40963f47f5d0463e7855dd9785454af4 179 SUPERFAMILY SSF56112 11 159 1.63E-10 T 01-11-2018 IPR011009 Protein kinase-like domain superfamily AFULGI_00026710 b862194d3b4159655cda5c921a67980e 58 ProDom PD256538 PF0630 PYRAB06030 AF2407.1 1 58 6.0E-29 T 01-11-2018 IPR020199 Uncharacterised protein family PYRAB06030 AFULGI_00022320 2dba5d04cd42c81e06ad1310c773a5aa 308 Pfam PF04981 NMD3 family 7 201 2.4E-39 T 01-11-2018 IPR007064 Nmd3, N-terminal AFULGI_00000970 38f9a1ba8d8e6321df8e6432b3527fad 93 Pfam PF03683 Uncharacterised protein family (UPF0175) 22 88 1.4E-16 T 01-11-2018 IPR005368 Uncharacterised protein family UPF0175 AFULGI_00007280 3032ca983cf6cc873f009c8162cce8d3 251 Gene3D G3DSA:3.50.50.60 33 249 2.9E-15 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFULGI_00014300 dbc1880a7df0ece126c146dca2e7c864 194 TIGRFAM TIGR04289 heavy_Cys: eight-cysteine-cluster domain 139 191 2.1E-22 T 01-11-2018 IPR027553 Eight-cysteine-cluster domain AFULGI_00025650 4fba7d950565ea2f320dbe8b36f85ef4 238 Gene3D G3DSA:2.40.400.10 1 238 7.9E-44 T 01-11-2018 IPR023375 Acetoacetate decarboxylase domain superfamily KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 AFULGI_00025650 4fba7d950565ea2f320dbe8b36f85ef4 238 Pfam PF06314 Acetoacetate decarboxylase (ADC) 4 236 8.9E-41 T 01-11-2018 IPR010451 Acetoacetate decarboxylase GO:0016829 KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 AFULGI_00025650 4fba7d950565ea2f320dbe8b36f85ef4 238 SUPERFAMILY SSF160104 13 230 6.41E-32 T 01-11-2018 IPR023375 Acetoacetate decarboxylase domain superfamily KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 AFULGI_00008640 08488c3d3b0517dd966688170c3b6bda 81 Pfam PF02416 mttA/Hcf106 family 2 47 2.1E-8 T 01-11-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 AFULGI_00006910 f140ccdf6172c084c41786d5919d64d9 128 TIGRFAM TIGR03698 clan_AA_DTGF: clan AA aspartic protease, AF_0612 family 8 122 3.0E-35 T 01-11-2018 IPR022274 Peptidase aspartic, AF0612 AFULGI_00001620 17b0ce60736dfe01c7274f199aba6bed 183 Pfam PF07853 Protein of unknown function (DUF1648) 22 66 1.6E-16 T 01-11-2018 IPR012867 Domain of unknown function DUF1648 AFULGI_00018720 294c9b448dcfc57a0d3ae8eb56316143 328 TIGRFAM TIGR00698 TIGR00698: conserved hypothetical protein 14 328 2.2E-141 T 01-11-2018 IPR004630 Uncharacterised protein family UPF0324, bacteria GO:0016021 AFULGI_00018720 294c9b448dcfc57a0d3ae8eb56316143 328 Pfam PF03601 Conserved hypothetical protein 698 22 307 4.5E-82 T 01-11-2018 IPR018383 Uncharacterised protein family UPF0324, prokaryote GO:0016021 AFULGI_00003030 457f758744c9fd27d9c852d3840d2b19 219 SUPERFAMILY SSF53448 17 158 7.76E-13 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFULGI_00003030 457f758744c9fd27d9c852d3840d2b19 219 Gene3D G3DSA:3.90.550.10 17 190 1.2E-11 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFULGI_00010740 ba08edca343195723b9791f88b267899 210 Pfam PF03379 CcmB protein 4 192 5.4E-11 T 01-11-2018 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 AFULGI_00003150 2a31f6cf13c64d3ca3683799a66e2442 55 SUPERFAMILY SSF88723 1 36 3.64E-5 T 01-11-2018 IPR029060 PIN-like domain superfamily AFULGI_00002640 f7ec5de3a69a4ddb84ebcc40f961ac64 232 Pfam PF02754 Cysteine-rich domain 84 175 1.7E-18 T 01-11-2018 IPR004017 Cysteine-rich domain AFULGI_00022850 b853dfe82b5cdd17c88ae60598158abe 191 ProDom PD695862 AF1173 AF0136 AF2020 1 185 1.0E-89 T 01-11-2018 AFULGI_00021600 de705d8517d411b72cf8a218f8dd73d2 228 SMART SM01415 42 228 1.0E-47 T 01-11-2018 IPR002809 Integral membrane protein EMC3/TMCO1-like GO:0016020 AFULGI_00021600 de705d8517d411b72cf8a218f8dd73d2 228 Pfam PF01956 Integral membrane protein DUF106 43 227 1.3E-53 T 01-11-2018 IPR002809 Integral membrane protein EMC3/TMCO1-like GO:0016020 AFULGI_00012720 5359837bed7e8276f29ed01f80017c46 197 ProDom PD695862 AF1173 AF0136 AF2020 5 182 2.0E-91 T 01-11-2018 AFULGI_00019030 4d35bff714535406c5d4556240aded88 329 Pfam PF17231 Family of unknown function (DUF5305) 130 325 3.7E-25 T 01-11-2018 IPR035185 Protein of unknown function DUF5305 AFULGI_00015980 8cabac345bc750675326c6aa692bc3d2 165 Pfam PF07790 Archaeal Type IV pilin, N-terminal 12 92 1.5E-15 T 01-11-2018 IPR012859 Archaeal Type IV pilin, N-terminal AFULGI_00013740 5b4670e8adcbea35fa25606b73b0a1ad 427 Pfam PF02514 CobN/Magnesium Chelatase 87 414 5.3E-74 T 01-11-2018 IPR003672 CobN/magnesium chelatase GO:0009058 AFULGI_00010500 d4f17fc110797ed2b581f651cac437d0 285 Pfam PF02653 Branched-chain amino acid transport system / permease component 28 272 2.5E-33 T 01-11-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 AFULGI_00025740 0f77e7161ba891e78c1b97c02fb835b7 295 Pfam PF07670 Nucleoside recognition 17 110 5.5E-8 T 01-11-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 AFULGI_00016630 45bda9c14a5ec45a54ae35d272effee4 243 SUPERFAMILY SSF48537 22 95 1.23E-5 T 01-11-2018 IPR008947 Phospholipase C/P1 nuclease domain superfamily GO:0016788 AFULGI_00019370 fda7344cae07390285488376023d56ae 274 Pfam PF01925 Sulfite exporter TauE/SafE 9 264 1.8E-34 T 01-11-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 AFULGI_00018010 1c0d3bda198654a291782d6cc2ad7485 47 Pfam PF03477 ATP cone domain 3 42 6.0E-7 T 01-11-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 AFULGI_00013710 679b43d505dd2c5e1da1b14785a62d26 52 Pfam PF09853 Putative transposon-encoded protein (DUF2080) 4 52 4.5E-23 T 01-11-2018 IPR019205 Protein of unknown function DUF2080, transposon-encoded AFULGI_00002680 155e868fb7e344f9a6b3b6b5ae529f8a 92 Pfam PF04324 BFD-like [2Fe-2S] binding domain 6 57 2.5E-14 T 01-11-2018 IPR007419 BFD-like [2Fe-2S]-binding domain AFULGI_00002680 155e868fb7e344f9a6b3b6b5ae529f8a 92 Gene3D G3DSA:1.10.10.1100 1 67 4.2E-21 T 01-11-2018 AFULGI_00025900 24f4e2b8566e0e798424006df71a2d17 261 SUPERFAMILY SSF49899 110 250 2.27E-6 T 01-11-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily AFULGI_00016770 cdff7557ff04145244d06cdfc8a2f805 600 SUPERFAMILY SSF52540 1 401 7.29E-25 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFULGI_00016770 cdff7557ff04145244d06cdfc8a2f805 600 Pfam PF13175 AAA ATPase domain 1 390 3.0E-46 T 01-11-2018 AFULGI_00008410 120c7bcc91e292e0a892ab8ba469dba3 959 SUPERFAMILY SSF53300 610 817 7.66E-11 T 01-11-2018 IPR036465 von Willebrand factor A-like domain superfamily AFULGI_00008410 120c7bcc91e292e0a892ab8ba469dba3 959 Gene3D G3DSA:3.40.50.410 602 817 7.5E-19 T 01-11-2018 IPR036465 von Willebrand factor A-like domain superfamily AFULGI_00007040 6f8844606bd6fc6dd6031a0adfb31d77 185 Pfam PF01944 Stage II sporulation protein M 16 179 5.8E-32 T 01-11-2018 IPR002798 Stage II sporulation protein M-like AFULGI_00019800 d89ae46d44920acea981e7f71cf7bb30 310 Gene3D G3DSA:3.30.1330.20 200 308 8.1E-21 T 01-11-2018 IPR037103 Tubulin/FtsZ, C-terminal domain superfamily Reactome: R-HSA-380320 AFULGI_00025960 3a5d58b5930a41185e10548401991fdf 510 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 1 499 8.9E-64 T 01-11-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 AFULGI_00018580 781b1852080f9fc0ebe2ee499d1877ef 248 Gene3D G3DSA:1.10.3720.10 2 245 5.7E-48 T 01-11-2018 IPR035906 MetI-like superfamily AFULGI_00018580 781b1852080f9fc0ebe2ee499d1877ef 248 SUPERFAMILY SSF161098 4 240 6.17E-51 T 01-11-2018 IPR035906 MetI-like superfamily AFULGI_00018580 781b1852080f9fc0ebe2ee499d1877ef 248 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 4 237 3.5E-9 T 01-11-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFULGI_00015040 30e57427ada7d7e51295077782898f28 343 Pfam PF02653 Branched-chain amino acid transport system / permease component 4 317 1.9E-70 T 01-11-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 AFULGI_00018410 c177bbfd7405a2f88f05c14e879609fc 286 Pfam PF01402 Ribbon-helix-helix protein, copG family 4 39 9.6E-8 T 01-11-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 AFULGI_00002620 2fb71b295b9bce2f45be9cc4496f7e36 60 ProDom PD052877 ARCHAEL AF0269 3 43 3.0E-17 T 01-11-2018 AFULGI_00003160 0681600421b8ee1170fbdb4bc8d8ec8a 93 Pfam PF01850 PIN domain 1 80 7.0E-8 T 01-11-2018 IPR002716 PIN domain AFULGI_00019840 6868de04591b7dccbb0e129828645a09 60 Pfam PF10133 Predicted RNA-binding protein 1 58 2.0E-20 T 01-11-2018 IPR019300 RNA-binding protein, predicted AFULGI_00006520 2e03ee2e71630ebea9b4474f720dab66 85 TIGRFAM TIGR04140 chp_AF_0576: TIGR04140 family protein 16 85 2.2E-26 T 01-11-2018 IPR026486 Uncharacterised protein AF_0576 AFULGI_00004680 732be9dba954ff01b5728967fa354c1c 276 Pfam PF01889 Membrane protein of unknown function DUF63 16 275 2.5E-94 T 01-11-2018 IPR002749 Protein of unknown function DUF63 AFULGI_00012770 dbbaf440dff600c019da383ba414bb54 63 Gene3D G3DSA:1.10.1040.10 1 63 2.2E-12 T 01-11-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AFULGI_00007370 aac028ce3d26789ec473ca58957ff5ba 145 Gene3D G3DSA:2.60.40.10 19 115 2.0E-5 T 01-11-2018 IPR013783 Immunoglobulin-like fold