locus-tag	class	description
Arcpr_0002	COG0179	Fumarylacetoacetate (FAA) hydrolase
Arcpr_0003	COG0525	valine-tRNA ligase activity
Arcpr_0007	COG1702	phosphate starvation-inducible protein PhoH
Arcpr_0011	COG1335	isochorismatase
Arcpr_0020	COG0107	imidazoleglycerol-phosphate synthase activity
Arcpr_0025	COG1694	Mazg nucleotide pyrophosphohydrolase
Arcpr_0032	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
Arcpr_0036	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
Arcpr_0037	COG0439	Biotin carboxylase
Arcpr_0040	COG1196	nuclear chromosome segregation
Arcpr_0042	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
Arcpr_0043	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
Arcpr_0044	COG1185	polyribonucleotide nucleotidyltransferase activity
Arcpr_0047	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
Arcpr_0052	COG0432	Pfam Uncharacterised protein family UPF0047
Arcpr_0053	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
Arcpr_0055	COG1881	PFAM PEBP family protein
Arcpr_0056	COG1104	cysteine desulfurase activity
Arcpr_0060	COG0419	ATPase involved in DNA repair
Arcpr_0060	COG0419	ATPase involved in DNA repair
Arcpr_0064	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
Arcpr_0066	COG2267	carboxylic ester hydrolase activity
Arcpr_0069	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Arcpr_0070	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Arcpr_0073	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
Arcpr_0078	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Arcpr_0079	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
Arcpr_0083	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Arcpr_0084	COG2078	PFAM AMMECR1 domain protein
Arcpr_0085	COG4608	Belongs to the ABC transporter superfamily
Arcpr_0086	COG0444	Belongs to the ABC transporter superfamily
Arcpr_0088	COG0601	transmembrane transport
Arcpr_0089	COG0747	negative chemotaxis
Arcpr_0091	COG0187	DNA topoisomerase II activity
Arcpr_0098	COG0573	inorganic phosphate transmembrane transporter activity
Arcpr_0100	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Arcpr_0101	COG0704	Plays a role in the regulation of phosphate uptake
Arcpr_0106	COG0009	L-threonylcarbamoyladenylate synthase
Arcpr_0108	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
Arcpr_0122	COG0210	DNA helicase
Arcpr_0131	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Arcpr_0133	COG0200	Binds to the 23S rRNA
Arcpr_0134	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
Arcpr_0136	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
Arcpr_0137	COG1201	RNA secondary structure unwinding
Arcpr_0138	COG1648	precorrin-2 dehydrogenase activity
Arcpr_0138	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Arcpr_0139	COG2221	Nitrite and sulphite reductase 4Fe-4S
Arcpr_0140	COG2221	Nitrite and sulphite reductase 4Fe-4S
Arcpr_0147	COG0402	S-adenosylhomocysteine deaminase activity
Arcpr_0148	COG0569	domain protein
Arcpr_0149	COG0805	protein transport
Arcpr_0151	COG1918	ferrous iron import across plasma membrane
Arcpr_0151	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
Arcpr_0158	COG1363	Peptidase, m42
Arcpr_0160	COG2037	Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT)
Arcpr_0162	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Arcpr_0163	COG0778	Nitroreductase
Arcpr_0166	COG1121	(ABC) transporter
Arcpr_0169	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
Arcpr_0170	COG1794	racemase activity, acting on amino acids and derivatives
Arcpr_0171	COG0028	Belongs to the TPP enzyme family
Arcpr_0172	COG0440	acetolactate synthase activity
Arcpr_0174	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
Arcpr_0179	COG0006	proline dipeptidase activity
Arcpr_0180	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Arcpr_0184	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
Arcpr_0186	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
Arcpr_0189	COG0301	tRNA thio-modification
Arcpr_0191	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
Arcpr_0192	COG2252	PERMEase
Arcpr_0201	COG0411	ABC transporter
Arcpr_0205	COG0159	tryptophan synthase activity
Arcpr_0206	COG0133	tryptophan synthase activity
Arcpr_0210	COG0512	Glutamine amidotransferase of anthranilate synthase
Arcpr_0211	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
Arcpr_0212	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Arcpr_0214	COG0423	glycine-tRNA ligase activity
Arcpr_0216	COG1618	nucleotide phosphatase activity, acting on free nucleotides
Arcpr_0217	COG1867	N(2),N(2)-dimethylguanosine tRNA methyltransferase
Arcpr_0221	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Arcpr_0221	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Arcpr_0224	COG0138	bifunctional purine biosynthesis protein purh
Arcpr_0227	COG0165	Argininosuccinate lyase
Arcpr_0228	COG0252	asparaginase activity
Arcpr_0231	COG0330	HflC and HflK could
Arcpr_0232	COG0457	Tetratricopeptide repeat
Arcpr_0232	COG0552	protein localization to endoplasmic reticulum
Arcpr_0240	COG1534	Rna-binding protein
Arcpr_0242	COG0321	lipoyl(octanoyl) transferase activity
Arcpr_0242	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
Arcpr_0243	COG2379	hydroxypyruvate reductase
Arcpr_0248	COG0538	isocitrate dehydrogenase activity
Arcpr_0249	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
Arcpr_0249	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Arcpr_0252	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Arcpr_0260	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
Arcpr_0266	COG0459	protein refolding
Arcpr_0267	COG0149	triose-phosphate isomerase activity
Arcpr_0268	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Arcpr_0269	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
Arcpr_0274	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Arcpr_0276	COG0460	homoserine dehydrogenase
Arcpr_0278	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Arcpr_0283	COG0551	DNA topoisomerase type I activity
Arcpr_0283	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Arcpr_0285	COG0857	belongs to the CobB CobQ family
Arcpr_0286	COG0045	succinate-CoA ligase (ADP-forming) activity
Arcpr_0286	COG1042	CoA-binding domain protein
Arcpr_0286	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Arcpr_0294	COG0315	cyclic pyranopterin monophosphate synthase activity
Arcpr_0296	COG0303	'Molybdopterin
Arcpr_0297	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Arcpr_0298	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Arcpr_0302	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
Arcpr_0303	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
Arcpr_0305	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
Arcpr_0308	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
Arcpr_0310	COG0409	Hydrogenase expression formation protein
Arcpr_0311	COG0298	carbon dioxide binding
Arcpr_0313	COG0375	protein maturation
Arcpr_0322	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
Arcpr_0324	COG1234	tRNA 3'-trailer cleavage
Arcpr_0325	COG0003	Pfam Anion-transporting ATPase
Arcpr_0326	COG0535	radical SAM domain protein
Arcpr_0330	COG1418	mRNA catabolic process
Arcpr_0331	COG0023	Translation Initiation Factor
Arcpr_0332	COG0101	tRNA pseudouridine synthase activity
Arcpr_0333	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Arcpr_0334	COG1136	(ABC) transporter
Arcpr_0339	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Arcpr_0344	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Arcpr_0344	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
Arcpr_0346	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
Arcpr_0347	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
Arcpr_0349	COG1945	arginine decarboxylase activity
Arcpr_0350	COG0126	phosphoglycerate kinase activity
Arcpr_0351	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Arcpr_0353	COG0492	ferredoxin-NADP+ reductase activity
Arcpr_0356	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
Arcpr_0359	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Arcpr_0361	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
Arcpr_0364	COG0719	Fe-S assembly protein
Arcpr_0374	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
Arcpr_0376	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
Arcpr_0379	COG0473	3-isopropylmalate dehydrogenase activity
Arcpr_0382	COG0174	glutamine synthetase
Arcpr_0384	COG0432	Pfam Uncharacterised protein family UPF0047
Arcpr_0386	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
Arcpr_0387	COG0517	IMP dehydrogenase activity
Arcpr_0390	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
Arcpr_0396	COG2131	deaminase
Arcpr_0410	COG0131	Imidazoleglycerol-phosphate dehydratase
Arcpr_0411	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
Arcpr_0412	COG0517	IMP dehydrogenase activity
Arcpr_0412	COG1994	Peptidase M50
Arcpr_0415	COG1122	ATPase activity
Arcpr_0420	COG0167	dihydroorotate dehydrogenase activity
Arcpr_0427	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
Arcpr_0428	COG0569	domain protein
Arcpr_0428	COG0475	glutathione-regulated potassium exporter activity
Arcpr_0433	COG1213	nucleotidyl transferase
Arcpr_0433	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Arcpr_0434	COG0489	protein tyrosine kinase activity
Arcpr_0439	COG1763	Mo-molybdopterin cofactor biosynthetic process
Arcpr_0440	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
Arcpr_0441	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
Arcpr_0443	COG0215	cysteine-tRNA ligase activity
Arcpr_0447	COG0456	acetyltransferase
Arcpr_0465	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
Arcpr_0467	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
Arcpr_0468	COG0585	pseudouridine synthase activity
Arcpr_0479	COG0430	RNA-3'-phosphate cyclase activity
Arcpr_0484	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
Arcpr_0491	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
Arcpr_0498	COG0105	UTP biosynthetic process
Arcpr_0499	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
Arcpr_0501	COG0436	Aminotransferase
Arcpr_0503	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Arcpr_0504	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
Arcpr_0512	COG1185	polyribonucleotide nucleotidyltransferase activity
Arcpr_0513	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
Arcpr_0515	COG0297	glycogen (starch) synthase activity
Arcpr_0524	COG2244	polysaccharide biosynthetic process
Arcpr_0527	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
Arcpr_0528	COG0436	Aminotransferase
Arcpr_0530	COG2095	MarC family integral membrane protein
Arcpr_0532	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
Arcpr_0533	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
Arcpr_0533	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
Arcpr_0536	COG2814	Major facilitator Superfamily
Arcpr_0537	COG2201	protein-glutamate methylesterase activity
Arcpr_0538	COG3290	protein histidine kinase activity
Arcpr_0539	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
Arcpr_0543	COG0746	molybdenum cofactor guanylyltransferase activity
Arcpr_0546	COG1793	dna ligase
Arcpr_0552	COG1522	sequence-specific DNA binding
Arcpr_0553	COG0730	response to heat
Arcpr_0560	COG1525	nuclease
Arcpr_0561	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Arcpr_0572	COG0076	glutamate decarboxylase activity
Arcpr_0574	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
Arcpr_0577	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
Arcpr_0579	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
Arcpr_0581	COG2814	Major facilitator Superfamily
Arcpr_0582	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
Arcpr_0582	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
Arcpr_0589	COG3769	mannosylglycerate metabolic process
Arcpr_0591	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
Arcpr_0592	COG0181	hydroxymethylbilane synthase activity
Arcpr_0593	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Arcpr_0596	COG0218	Necessary for normal cell division and for the maintenance of normal septation
Arcpr_0598	COG1628	Protein of unknown function DUF99
Arcpr_0601	COG1185	polyribonucleotide nucleotidyltransferase activity
Arcpr_0606	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
Arcpr_0608	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
Arcpr_0621	COG0446	pyridine nucleotide-disulphide oxidoreductase
Arcpr_0622	COG0039	L-malate dehydrogenase activity
Arcpr_0624	COG5002	protein histidine kinase activity
Arcpr_0627	COG1059	Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine 7-oxoG) from DNA. Also nicks DNA at apurinic apyrimidinic sites (AP sites)
Arcpr_0629	COG0450	alkyl hydroperoxide reductase
Arcpr_0631	COG1592	Rubrerythrin
Arcpr_0632	COG1773	rubredoxin
Arcpr_0633	COG2033	superoxide reductase activity
Arcpr_0634	COG0426	domain, Protein
Arcpr_0638	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Arcpr_0641	COG1131	(ABC) transporter
Arcpr_0643	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
Arcpr_0649	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Arcpr_0651	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Arcpr_0655	COG1067	ATP-dependent peptidase activity
Arcpr_0655	COG0470	DNA polymerase III
Arcpr_0659	COG1691	(AIR) carboxylase
Arcpr_0660	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
Arcpr_0662	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
Arcpr_0663	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
Arcpr_0669	COG1846	Transcriptional regulator
Arcpr_0672	COG3381	protein complex oligomerization
Arcpr_0674	COG3383	formate dehydrogenase (NAD+) activity
Arcpr_0674	COG0243	molybdopterin cofactor binding
Arcpr_0675	COG0437	4 iron, 4 sulfur cluster binding
Arcpr_0680	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
Arcpr_0681	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
Arcpr_0683	COG1136	(ABC) transporter
Arcpr_0684	COG0577	efflux transmembrane transporter activity
Arcpr_0687	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Arcpr_0691	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Arcpr_0694	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
Arcpr_0697	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Arcpr_0704	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Arcpr_0705	COG1615	UPF0182 protein
Arcpr_0708	COG0460	homoserine dehydrogenase
Arcpr_0708	COG0527	aspartate kinase activity
Arcpr_0723	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Arcpr_0724	COG2264	protein methyltransferase activity
Arcpr_0731	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
Arcpr_0733	COG0730	response to heat
Arcpr_0739	COG0501	Belongs to the peptidase M48B family
Arcpr_0743	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Arcpr_0745	COG0284	orotidine-5'-phosphate decarboxylase activity
Arcpr_0746	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Arcpr_0751	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Arcpr_0752	COG0475	glutathione-regulated potassium exporter activity
Arcpr_0753	COG2985	domain, Protein
Arcpr_0753	COG0490	domain, Protein
Arcpr_0755	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
Arcpr_0757	COG0442	prolyl-tRNA aminoacylation
Arcpr_0758	COG0037	tRNA processing
Arcpr_0762	COG1144	Oxidoreductase
Arcpr_0763	COG0674	pyruvate-flavodoxin oxidoreductase activity
Arcpr_0764	COG1013	pyruvate-flavodoxin oxidoreductase activity
Arcpr_0765	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Arcpr_0766	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Arcpr_0766	COG1213	nucleotidyl transferase
Arcpr_0770	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
Arcpr_0771	COG2835	tetraacyldisaccharide 4'-kinase activity
Arcpr_0772	COG0504	CTP synthase activity
Arcpr_0773	COG0543	2 iron, 2 sulfur cluster binding
Arcpr_0792	COG0305	Participates in initiation and elongation during chromosome replication
Arcpr_0792	COG1372	Participates in initiation and elongation during chromosome replication
Arcpr_0794	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Arcpr_0795	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
Arcpr_0796	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
Arcpr_0798	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Arcpr_0809	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
Arcpr_0811	COG1222	aaa ATPase
Arcpr_0817	COG1830	Aldolase
Arcpr_0820	COG0047	phosphoribosylformylglycinamidine synthase activity
Arcpr_0822	COG1185	polyribonucleotide nucleotidyltransferase activity
Arcpr_0824	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
Arcpr_0843	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
Arcpr_0849	COG1404	Belongs to the peptidase S8 family
Arcpr_0868	COG0688	phosphatidylethanolamine metabolic process
Arcpr_0869	COG1183	phosphatidylcholine synthase activity
Arcpr_0872	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
Arcpr_0873	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
Arcpr_0875	COG2226	methyltransferase
Arcpr_0877	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
Arcpr_0881	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
Arcpr_0885	COG1078	dGTPase activity
Arcpr_0919	COG0247	lactate metabolic process
Arcpr_0919	COG2181	nitrate reductase activity
Arcpr_0922	COG0442	prolyl-tRNA aminoacylation
Arcpr_0924	COG1397	ADP-ribosylglycohydrolase
Arcpr_0925	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
Arcpr_0926	COG1110	DNA topoisomerase II activity
Arcpr_0927	COG0864	Transcriptional regulator
Arcpr_0929	COG1522	sequence-specific DNA binding
Arcpr_0931	COG0019	diaminopimelate decarboxylase activity
Arcpr_0933	COG0519	Catalyzes the synthesis of GMP from XMP
Arcpr_0933	COG0518	GMP synthase (glutamine-hydrolyzing) activity
Arcpr_0935	COG0109	protoheme IX farnesyltransferase activity
Arcpr_0938	COG0052	Belongs to the universal ribosomal protein uS2 family
Arcpr_0940	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
Arcpr_0961	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
Arcpr_0962	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
Arcpr_0962	COG0321	lipoyl(octanoyl) transferase activity
Arcpr_0964	COG4555	ABC transporter
Arcpr_0967	COG1615	UPF0182 protein
Arcpr_0968	COG2814	Major facilitator Superfamily
Arcpr_0969	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Arcpr_0973	COG1830	Aldolase
Arcpr_0974	COG1465	3-dehydroquinate synthase
Arcpr_0976	COG0085	RNA polymerase activity
Arcpr_0978	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
Arcpr_0979	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
Arcpr_0980	COG1358	cellular component organization or biogenesis
Arcpr_0981	COG0195	Participates in both transcription termination and antitermination
Arcpr_0983	COG0049	tRNA binding
Arcpr_0984	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Arcpr_0988	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
Arcpr_0989	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Arcpr_0990	COG3252	Catalyzes the hydrolysis of methenyl-H(4)MPT( ) to 5- formyl-H(4)MPT
Arcpr_0991	COG0066	3-isopropylmalate dehydratase activity
Arcpr_0992	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
Arcpr_0996	COG2201	protein-glutamate methylesterase activity
Arcpr_0997	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
Arcpr_0998	COG0017	Asparaginyl-tRNA synthetase
Arcpr_0999	COG0083	homoserine kinase activity
Arcpr_1003	COG0656	L-ascorbic acid biosynthetic process
Arcpr_1006	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
Arcpr_1007	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
Arcpr_1008	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
Arcpr_1012	COG1120	ATPase activity
Arcpr_1013	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Arcpr_1014	COG4607	ABC-type enterochelin transport system periplasmic component
Arcpr_1019	COG0518	GMP synthase (glutamine-hydrolyzing) activity
Arcpr_1019	COG0519	Catalyzes the synthesis of GMP from XMP
Arcpr_1024	COG0312	modulator of DNA gyrase
Arcpr_1026	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
Arcpr_1027	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
Arcpr_1032	COG1509	lysine 2,3-aminomutase activity
Arcpr_1033	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
Arcpr_1035	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
Arcpr_1037	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
Arcpr_1038	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
Arcpr_1039	COG0318	PFAM AMP-dependent synthetase and ligase
Arcpr_1040	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Arcpr_1041	COG1812	S-adenosylmethionine synthetase (AdoMet synthetase)
Arcpr_1042	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
Arcpr_1045	COG1355	regulation of microtubule-based process
Arcpr_1047	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Arcpr_1049	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Arcpr_1050	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
Arcpr_1052	COG1795	PFAM Formaldehyde-activating enzyme (Fae)
Arcpr_1053	COG1227	inorganic diphosphatase activity
Arcpr_1054	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Arcpr_1055	COG1546	Belongs to the CinA family
Arcpr_1055	COG1058	Belongs to the CinA family
Arcpr_1058	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
Arcpr_1058	COG0167	dihydroorotate dehydrogenase activity
Arcpr_1059	COG0674	pyruvate-flavodoxin oxidoreductase activity
Arcpr_1060	COG1013	pyruvate-flavodoxin oxidoreductase activity
Arcpr_1063	COG1120	ATPase activity
Arcpr_1064	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Arcpr_1070	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
Arcpr_1074	COG0434	BtpA family
Arcpr_1077	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Arcpr_1079	COG1515	deoxyribonuclease V activity
Arcpr_1081	COG1444	tRNA N-acetyltransferase activity
Arcpr_1082	COG0589	response to stress
Arcpr_1086	COG0183	Belongs to the thiolase family
Arcpr_1090	COG0840	transmembrane signaling receptor activity
Arcpr_1093	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Arcpr_1095	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
Arcpr_1101	COG0010	Belongs to the arginase family
Arcpr_1104	COG0151	Belongs to the GarS family
Arcpr_1105	COG1047	Peptidyl-prolyl cis-trans
Arcpr_1110	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Arcpr_1111	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
Arcpr_1115	COG0569	domain protein
Arcpr_1117	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
Arcpr_1118	COG0540	Belongs to the ATCase OTCase family
Arcpr_1121	COG0436	Aminotransferase
Arcpr_1122	COG0372	Belongs to the citrate synthase family
Arcpr_1134	COG0477	Major facilitator Superfamily
Arcpr_1136	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Arcpr_1180	COG2886	Uncharacterised protein family (UPF0175)
Arcpr_1183	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Arcpr_1195	COG1216	Glycosyl transferase, family 2
Arcpr_1196	COG0438	transferase activity, transferring glycosyl groups
Arcpr_1198	COG1088	dTDP-glucose 4,6-dehydratase activity
Arcpr_1198	COG1088	dTDP-glucose 4,6-dehydratase activity
Arcpr_1202	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
Arcpr_1204	COG0463	Glycosyl transferase, family 2
Arcpr_1207	COG1216	Glycosyl transferase, family 2
Arcpr_1207	COG0438	transferase activity, transferring glycosyl groups
Arcpr_1212	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Arcpr_1214	COG0463	Glycosyl transferase, family 2
Arcpr_1218	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
Arcpr_1222	COG0598	Magnesium transport protein CorA
Arcpr_1227	COG0309	Hydrogenase expression formation protein (HypE)
Arcpr_1228	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
Arcpr_1229	COG0587	DNA-directed DNA polymerase activity
Arcpr_1236	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
Arcpr_1238	COG0306	phosphate transporter
Arcpr_1241	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
Arcpr_1241	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
Arcpr_1250	COG0546	phosphoglycolate phosphatase activity
Arcpr_1256	COG1980	fructose-bisphosphate aldolase activity
Arcpr_1257	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
Arcpr_1264	COG2046	Belongs to the sulfate adenylyltransferase family
Arcpr_1266	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
Arcpr_1269	COG0535	radical SAM domain protein
Arcpr_1270	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Arcpr_1273	COG1125	glycine betaine transport
Arcpr_1273	COG0517	IMP dehydrogenase activity
Arcpr_1279	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Arcpr_1280	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
Arcpr_1283	COG5002	protein histidine kinase activity
Arcpr_1287	COG0495	leucyl-tRNA aminoacylation
Arcpr_1290	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
Arcpr_1291	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
Arcpr_1296	COG2239	Acts as a magnesium transporter
Arcpr_1297	COG0140	phosphoribosyl-ATP diphosphatase activity
Arcpr_1297	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
Arcpr_1299	COG2226	methyltransferase
Arcpr_1301	COG0066	3-isopropylmalate dehydratase activity
Arcpr_1302	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
Arcpr_1303	COG1125	glycine betaine transport
Arcpr_1303	COG0517	IMP dehydrogenase activity
Arcpr_1304	COG0517	IMP dehydrogenase activity
Arcpr_1309	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Arcpr_1310	COG0154	amidase activity
Arcpr_1311	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
Arcpr_1323	COG0410	ABC transporter
Arcpr_1325	COG1234	tRNA 3'-trailer cleavage
Arcpr_1326	COG0051	transcription antitermination factor activity, RNA binding
Arcpr_1332	COG2414	aldehyde ferredoxin oxidoreductase
Arcpr_1334	COG0563	adenylate kinase activity
Arcpr_1339	COG0200	Binds to the 23S rRNA
Arcpr_1341	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
Arcpr_1345	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
Arcpr_1346	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
Arcpr_1347	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
Arcpr_1351	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
Arcpr_1352	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
Arcpr_1354	COG0255	Belongs to the universal ribosomal protein uL29 family
Arcpr_1355	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
Arcpr_1356	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
Arcpr_1357	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
Arcpr_1358	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Arcpr_1359	COG0089	rRNA binding
Arcpr_1361	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
Arcpr_1365	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
Arcpr_1372	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
Arcpr_1373	COG1776	CheC inhibitor of MCP methylation
Arcpr_1374	COG0643	Histidine kinase
Arcpr_1374	COG2198	Histidine kinase
Arcpr_1375	COG2201	protein-glutamate methylesterase activity
Arcpr_1376	COG2201	protein-glutamate methylesterase activity
Arcpr_1378	COG0835	chemotaxis
Arcpr_1379	COG0840	transmembrane signaling receptor activity
Arcpr_1386	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
Arcpr_1393	COG0037	tRNA processing
Arcpr_1399	COG0516	GMP reductase activity
Arcpr_1399	COG0517	IMP dehydrogenase activity
Arcpr_1406	COG4948	Mandelate Racemase Muconate Lactonizing
Arcpr_1408	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
Arcpr_1409	COG0145	ligase activity
Arcpr_1413	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
Arcpr_1418	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
Arcpr_1420	COG0459	protein refolding
Arcpr_1423	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
Arcpr_1424	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
Arcpr_1425	COG1051	belongs to the nudix hydrolase family
Arcpr_1425	COG1056	cytidyltransferase-related domain
Arcpr_1432	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
Arcpr_1433	COG0113	porphobilinogen synthase activity
Arcpr_1434	COG0436	Aminotransferase
Arcpr_1436	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
Arcpr_1439	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Arcpr_1443	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Arcpr_1447	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
Arcpr_1452	COG0489	protein tyrosine kinase activity
Arcpr_1456	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Arcpr_1456	COG0574	Belongs to the PEP-utilizing enzyme family
Arcpr_1457	COG0142	geranyltranstransferase activity
Arcpr_1458	COG0116	Belongs to the methyltransferase superfamily
Arcpr_1458	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
Arcpr_1465	COG0560	Phosphoserine phosphatase
Arcpr_1465	COG3830	Belongs to the UPF0237 family
Arcpr_1467	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
Arcpr_1470	COG1205	dead DEAH box helicase
Arcpr_1470	COG1111	helicase
Arcpr_1472	COG0024	Methionine aminopeptidase
Arcpr_1474	COG0521	Mo-molybdopterin cofactor biosynthetic process
Arcpr_1535	COG5016	pyruvate
Arcpr_1535	COG0511	ligase activity, forming carbon-carbon bonds
Arcpr_1537	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
Arcpr_1539	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
Arcpr_1546	COG0077	Prephenate dehydratase
Arcpr_1546	COG1605	Chorismate mutase
Arcpr_1547	COG0572	uridine kinase
Arcpr_1550	COG3259	Nickel-dependent hydrogenase
Arcpr_1555	COG1233	COG1233 Phytoene dehydrogenase and related
Arcpr_1558	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Arcpr_1561	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
Arcpr_1564	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
Arcpr_1566	COG1120	ATPase activity
Arcpr_1570	COG2050	protein possibly involved in aromatic compounds catabolism
Arcpr_1571	COG0137	argininosuccinate synthase activity
Arcpr_1572	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Arcpr_1573	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
Arcpr_1573	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
Arcpr_1578	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Arcpr_1578	COG0649	NAD binding
Arcpr_1578	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Arcpr_1580	COG1007	ATP synthesis coupled electron transport
Arcpr_1581	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
Arcpr_1582	COG0651	ATP synthesis coupled electron transport
Arcpr_1587	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Arcpr_1595	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
Arcpr_1597	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
Arcpr_1599	COG0351	phosphomethylpyrimidine kinase
Arcpr_1600	COG2860	membrane
Arcpr_1617	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
Arcpr_1618	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
Arcpr_1619	COG0587	DNA-directed DNA polymerase activity
Arcpr_1620	COG2814	Major facilitator Superfamily
Arcpr_1621	COG1418	mRNA catabolic process
Arcpr_1622	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
Arcpr_1624	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
Arcpr_1629	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Arcpr_1631	COG0443	Heat shock 70 kDa protein
Arcpr_1632	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Arcpr_1634	COG1850	ribulose-bisphosphate carboxylase activity
Arcpr_1637	COG2855	membrane
Arcpr_1639	COG1269	ATP hydrolysis coupled proton transport
Arcpr_1645	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
Arcpr_1646	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
Arcpr_1647	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
Arcpr_1653	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
Arcpr_1657	COG1201	RNA secondary structure unwinding
Arcpr_1657	COG1201	RNA secondary structure unwinding
Arcpr_1661	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
Arcpr_1714	COG1573	uracil-dna glycosylase
Arcpr_1719	COG0438	transferase activity, transferring glycosyl groups
Arcpr_1724	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Arcpr_1725	COG1797	cobyrinic acid a,c-diamide synthase activity
Arcpr_1727	COG0437	4 iron, 4 sulfur cluster binding
Arcpr_1734	COG0081	regulation of translation
Arcpr_1735	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
Arcpr_1737	COG1371	PFAM Archease protein family (DUF101 UPF0211)
Arcpr_1738	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
Arcpr_1741	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
Arcpr_1782	COG1525	nuclease
Arcpr_1797	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
Arcpr_1798	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Arcpr_1811	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
Arcpr_1812	COG3842	ATPase activity
Arcpr_1813	COG4149	molybdate abc transporter
Arcpr_1814	COG0725	ABC transporter, periplasmic molybdate-binding protein
Arcpr_1823	COG0343	queuine tRNA-ribosyltransferase activity
Arcpr_1825	COG0358	DNA primase activity
Arcpr_1838	COG0697	spore germination
Arcpr_1843	COG1053	succinate dehydrogenase
Arcpr_1845	COG0559	Belongs to the binding-protein-dependent transport system permease family
Arcpr_1847	COG0411	ABC transporter
Arcpr_1848	COG0410	ABC transporter
Arcpr_1849	COG0281	malic enzyme