locus-tag	class	description
Arcve_0002	ENOG4105D0U	Arsenite-activated ATPase (ArsA)
Arcve_0004	ENOG4107T0X	DNA ligase
Arcve_0039	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
Arcve_0044	ENOG4105DZS	Phenylacetate-CoA ligase
Arcve_0046	ENOG4105F7P	transcriptional regulator AsnC family
Arcve_0047	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
Arcve_0050	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
Arcve_0051	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
Arcve_0059	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
Arcve_0062	ENOG4107QSA	Oxaloacetate decarboxylase
Arcve_0064	ENOG4105EQR	Transposase IS116 IS110 IS902
Arcve_0066	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
Arcve_0067	ENOG4108IFG	nitrite reductase, (NAD(P)H)
Arcve_0071	ENOG4108YZY	peptidylprolyl cis-trans isomerase
Arcve_0073	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
Arcve_0074	ENOG4108ZPQ	MazG nucleotide pyrophosphohydrolase
Arcve_0077	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
Arcve_0087	ENOG4108UK2	deaminase
Arcve_0088	ENOG4105EYA	deoxyribonuclease
Arcve_0090	ENOG4105CJW	magnesium transporter
Arcve_0091	ENOG4105KPZ	phosphoribosyl-atp pyrophosphatase
Arcve_0093	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
Arcve_0094	ENOG4108S4C	acetyltransferase
Arcve_0096	ENOG4105DB7	PHP domain protein
Arcve_0100	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
Arcve_0113	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
Arcve_0115	ENOG4105DVY	radical SAM domain protein
Arcve_0125	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
Arcve_0127	ENOG4105F1A	Pyruvate formate-lyase
Arcve_0128	ENOG4105DK7	lysyl-tRNA synthetase
Arcve_0131	ENOG4105KST	dependent repressor
Arcve_0138	ENOG4108USZ	hydrogenase
Arcve_0140	ENOG4105DPX	Hydrogenase, large subunit
Arcve_0141	ENOG4105E3S	small subunit
Arcve_0146	ENOG4107YZX	Universal stress protein
Arcve_0152	ENOG4107RY6	amino acid
Arcve_0161	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
Arcve_0162	ENOG4107RSS	Hydrogenase accessory protein HypB
Arcve_0165	ENOG4105E2X	shikimate dehydrogenase
Arcve_0166	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
Arcve_0173	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
Arcve_0175	ENOG4105C75	arginyL-tRNA synthetase
Arcve_0176	ENOG4105CE1	Ferrous iron transport protein b
Arcve_0180	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
Arcve_0186	ENOG4105BZU	Histidine kinase
Arcve_0187	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
Arcve_0189	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
Arcve_0190	ENOG4105WH1	Two component transcriptional regulator luxr family
Arcve_0194	ENOG4105DQE	DNA ligase
Arcve_0195	ENOG4107ZT3	family UPF0126
Arcve_0203	ENOG4108MGF	sugar kinase
Arcve_0208	ENOG4105FDF	Could be involved in DNA repair (By similarity)
Arcve_0209	ENOG4105DQE	DNA ligase
Arcve_0212	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
Arcve_0215	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
Arcve_0219	ENOG4108ZAF	Molybdopterin
Arcve_0221	ENOG4105MRR	Transcriptional regulator (By similarity)
Arcve_0222	ENOG4105K4W	Could be involved in septation (By similarity)
Arcve_0223	ENOG4105C5S	asparaginyl-tRNA synthetase
Arcve_0227	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
Arcve_0228	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
Arcve_0233	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
Arcve_0239	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
Arcve_0241	ENOG4108UH6	UPF0754 membrane protein
Arcve_0242	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
Arcve_0243	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
Arcve_0248	ENOG4108JJB	ABC transporter
Arcve_0249	ENOG4107ZYJ	bioY protein
Arcve_0258	ENOG4105CJ1	ABC, transporter
Arcve_0266	ENOG4105EWC	Purine nucleoside phosphorylase
Arcve_0267	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
Arcve_0269	ENOG4105HDK	L-asparaginase
Arcve_0270	ENOG4105CH7	arginosuccinase
Arcve_0273	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
Arcve_0276	ENOG4105CVK	Glutamate decarboxylase
Arcve_0277	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
Arcve_0278	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
Arcve_0280	ENOG4105CIH	Imidazole acetol-phosphate transaminase
Arcve_0283	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
Arcve_0287	ENOG4105CHM	Aminotransferase
Arcve_0302	ENOG41089ID	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
Arcve_0304	ENOG4108JIQ	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity)
Arcve_0305	ENOG4108JIP	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit (By similarity)
Arcve_0308	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
Arcve_0310	ENOG41081FK	Mediates zinc uptake. May also transport other divalent cations (By similarity)
Arcve_0317	ENOG4105EIH	LPPG Fo 2-phospho-L-lactate transferase
Arcve_0323	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
Arcve_0327	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
Arcve_0328	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
Arcve_0330	ENOG4107QN1	sodium solute
Arcve_0332	ENOG4105C2X	Arabinose 5-phosphate isomerase
Arcve_0333	ENOG41083X2	DNA polymerase III, epsilon subunit
Arcve_0336	ENOG4105FIE	Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT) (By similarity)
Arcve_0347	ENOG4105C8Q	Methyl-accepting chemotaxis
Arcve_0354	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
Arcve_0355	ENOG4105VB5	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
Arcve_0358	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
Arcve_0360	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Arcve_0361	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
Arcve_0362	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
Arcve_0368	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
Arcve_0369	ENOG4108JVH	Protein of unknown function DUF43
Arcve_0370	ENOG4105D1F	ATP-binding protein
Arcve_0372	ENOG4105DCC	Formylmethanofuran dehydrogenase subunit A
Arcve_0376	ENOG41080XP	Cbs domain
Arcve_0380	ENOG4105BZU	Histidine kinase
Arcve_0396	ENOG4107SSZ	Phosphatase
Arcve_0398	ENOG41071I4	Phosphatidylserine decarboxylase proenzyme
Arcve_0399	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
Arcve_0403	ENOG4108R96	Methyltransferase, YaeB family
Arcve_0406	ENOG4105CHM	Aminotransferase
Arcve_0408	ENOG4105PW4	Sugar fermentation stimulation protein homolog
Arcve_0410	ENOG4105E3H	phosphoglycerate mutase
Arcve_0415	ENOG4105C3G	gtp-binding protein
Arcve_0420	ENOG4107RIQ	Sulfate adenylate transferase
Arcve_0424	ENOG4105EWK	phytoene
Arcve_0425	ENOG4108EQM	faD-dependent pyridine nucleotide-disulfide oxidoreductase
Arcve_0430	ENOG41061GT	Aldolase
Arcve_0431	ENOG4106M32	3-dehydroquinate synthase
Arcve_0432	ENOG4105FF2	Type I DHQase
Arcve_0433	ENOG4105CQC	Prephenate dehydratase
Arcve_0434	ENOG4108NGU	Transcriptional regulator
Arcve_0435	ENOG4105CJ1	ABC, transporter
Arcve_0436	ENOG4107QWP	ABC-2 type transporter
Arcve_0443	ENOG4106C07	ThiamineS Protein
Arcve_0449	ENOG4105UIB	(ABC) transporter
Arcve_0450	ENOG4108JQ9	ABC transporter
Arcve_0451	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
Arcve_0452	ENOG4105VYW	UPF0251 protein
Arcve_0456	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
Arcve_0457	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
Arcve_0461	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
Arcve_0470	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
Arcve_0502	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
Arcve_0503	ENOG4105D52	delta-aminolevulinic acid dehydratase
Arcve_0504	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
Arcve_0505	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
Arcve_0509	ENOG4105CK7	Sodium proline symporter
Arcve_0510	ENOG4105D1F	ATP-binding protein
Arcve_0512	ENOG4105CUB	amino acid
Arcve_0513	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
Arcve_0514	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
Arcve_0515	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
Arcve_0517	ENOG4105D0M	Protease HtpX homolog
Arcve_0518	ENOG4108MDK	Dehydrogenase
Arcve_0522	ENOG4105D65	subunit l
Arcve_0523	ENOG4105D65	subunit l
Arcve_0526	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Arcve_0528	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
Arcve_0535	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
Arcve_0541	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
Arcve_0546	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
Arcve_0551	ENOG4107ZIM	Dtdp-4-dehydrorhamnose 3,5-epimerase
Arcve_0553	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
Arcve_0562	ENOG4106WTF	Glycosyl transferase, family 2
Arcve_0564	ENOG4105CIB	oxidoreductase Domain protein
Arcve_0566	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
Arcve_0580	ENOG4107T0X	DNA ligase
Arcve_0586	ENOG4107QZT	geranylgeranyl reductase
Arcve_0587	ENOG4108J8Z	aliphatic sulfonates family ABC transporter periplasmic ligand-binding protein
Arcve_0589	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
Arcve_0592	ENOG4105C2N	RNA methyltransferase TrmH family group 3
Arcve_0596	ENOG41087NI	Sulfite exporter TauE/SafE
Arcve_0597	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
Arcve_0598	ENOG41074MP	UPF0103 Mediator of ErbB2-driven cell motility-containing protein
Arcve_0599	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
Arcve_0604	ENOG4105DGU	Histone deacetylase
Arcve_0611	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
Arcve_0615	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
Arcve_0616	ENOG4105SHT	UspA domain-containing protein
Arcve_0617	ENOG4105E3H	phosphoglycerate mutase
Arcve_0618	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
Arcve_0620	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
Arcve_0622	ENOG4107QRT	dEAD DEAH box helicase
Arcve_0623	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
Arcve_0624	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
Arcve_0628	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
Arcve_0629	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
Arcve_0638	ENOG4105KY8	Rubrerythrin
Arcve_0648	ENOG4107RZH	Nitrite and sulphite reductase 4Fe-4S region
Arcve_0650	ENOG4108RAC	Rubrerythrin
Arcve_0651	ENOG4105D3R	alkyl hydroperoxide reductase
Arcve_0688	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
Arcve_0691	ENOG4108YZA	Nitrogen regulatory protein pii
Arcve_0694	ENOG4105D0C	transport protein
Arcve_0695	ENOG4107S91	Sodium hydrogen exchanger
Arcve_0696	ENOG4105BZU	Histidine kinase
Arcve_0698	ENOG4105CNW	domain protein
Arcve_0699	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
Arcve_0700	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
Arcve_0701	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
Arcve_0707	ENOG4105K8R	UPF0145 protein
Arcve_0711	ENOG4105E2K	Glycosyl transferase (Group 1
Arcve_0716	ENOG4107XDQ	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
Arcve_0717	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
Arcve_0720	ENOG4105QAX	Iron-sulfur
Arcve_0721	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
Arcve_0725	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
Arcve_0736	ENOG41071TK	Uncharacterised protein family (UPF0150)
Arcve_0740	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
Arcve_0746	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
Arcve_0747	ENOG4105ERH	Fumarylacetoacetate hydrolase
Arcve_0749	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
Arcve_0750	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
Arcve_0753	ENOG4105C1A	potassium transporter peripheral membrane
Arcve_0754	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
Arcve_0758	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
Arcve_0765	ENOG4105CPF	Cell wall formation (By similarity)
Arcve_0768	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
Arcve_0769	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
Arcve_0772	ENOG4105CK7	Sodium proline symporter
Arcve_0773	ENOG4105DTT	CRISPR-associated helicase, cas3
Arcve_0778	ENOG4105ZHF	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
Arcve_0779	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
Arcve_0782	ENOG4105E63	Pfam:DUF178
Arcve_0786	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
Arcve_0789	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
Arcve_0794	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
Arcve_0795	ENOG4105D8K	carboxyl transferase
Arcve_0796	ENOG4105DDK	oxidoreductase, beta subunit
Arcve_0797	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
Arcve_0799	ENOG4105CDJ	oxidoreductase FAD NAD(P)-binding domain protein
Arcve_0800	ENOG4105BZ8	glutamate synthase
Arcve_0804	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
Arcve_0806	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
Arcve_0808	ENOG41079Y2	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone
Arcve_0813	ENOG4108R96	Methyltransferase, YaeB family
Arcve_0814	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
Arcve_0819	ENOG4105C0Z	ABC transporter
Arcve_0820	ENOG4108IV0	ABC, transporter
Arcve_0822	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
Arcve_0823	ENOG4105DKQ	ROK family
Arcve_0825	ENOG4105EE8	May catalyze the methylation of C-1 in cobalt-precorrin- 5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A (By similarity)
Arcve_0826	ENOG4105E4R	Precorrin-3B C17-methyltransferase
Arcve_0827	ENOG4108P62	biosynthesis protein (CbiG)
Arcve_0828	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
Arcve_0829	ENOG4105DVK	Precorrin-2 c20-methyltransferase
Arcve_0833	ENOG4105CFT	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity)
Arcve_0848	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
Arcve_0853	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
Arcve_0861	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
Arcve_0862	ENOG4105C79	DNA protecting protein DprA
Arcve_0865	ENOG4107XF7	NGG1p interacting factor 3 protein, NIF3
Arcve_0867	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
Arcve_0868	ENOG4105C8U	phosphate abc transporter
Arcve_0869	ENOG4105C8U	phosphate abc transporter
Arcve_0870	ENOG4105CVA	phosphate
Arcve_0887	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
Arcve_0890	ENOG4105E5Q	amino acid AbC transporter
Arcve_0891	ENOG4107R0W	ABC transporter
Arcve_0902	ENOG4105CY0	Metallo-Beta-Lactamase
Arcve_0905	ENOG4107NFR	Fructose-1,6-bisphosphatase
Arcve_0906	ENOG4105EHU	Circadian clock protein KaiC
Arcve_0908	ENOG4106K5Q	Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication (By similarity)
Arcve_0909	ENOG4105EHU	Circadian clock protein KaiC
Arcve_0917	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
Arcve_0919	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
Arcve_0920	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
Arcve_0921	ENOG41080HJ	6-phospho 3-hexuloisomerase
Arcve_0922	ENOG4105CN9	Peptidase m42 family protein
Arcve_0927	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
Arcve_0929	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
Arcve_0930	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
Arcve_0931	ENOG4107TH8	cina domain protein
Arcve_0940	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
Arcve_0942	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
Arcve_0943	ENOG4107Z3D	50S ribosomal protein l10
Arcve_0951	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
Arcve_0952	ENOG4107WPW	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
Arcve_0953	ENOG41080V4	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
Arcve_0956	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
Arcve_0958	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
Arcve_0960	ENOG4107RB4	Cytidine monophosphate kinase
Arcve_0962	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
Arcve_0965	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
Arcve_0969	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
Arcve_0970	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
Arcve_0972	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
Arcve_0974	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
Arcve_0975	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
Arcve_0976	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
Arcve_0978	ENOG41082SA	50s ribosomal protein l29
Arcve_0979	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
Arcve_0980	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
Arcve_0981	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
Arcve_0982	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Arcve_0983	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
Arcve_0985	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
Arcve_0988	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
Arcve_0991	ENOG4105C8N	cysteinyl-tRNA synthetase
Arcve_0993	ENOG4105C8I	hydrolase, family 38
Arcve_0994	ENOG4108ZFX	Mannosyl-3-phosphoglycerate phosphatase
Arcve_0998	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
Arcve_1000	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
Arcve_1001	ENOG4105EHG	Permease protein
Arcve_1004	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
Arcve_1005	ENOG4105C0Z	ABC transporter
Arcve_1007	ENOG4105C32	Amino acid ABC transporter (Permease)
Arcve_1008	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
Arcve_1010	ENOG4108IV0	ABC, transporter
Arcve_1017	ENOG4107T1U	Catalyzes the synthesis of activated sulfate (By similarity)
Arcve_1018	ENOG4105C1J	atp-dependent rna helicase
Arcve_1022	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
Arcve_1024	ENOG4105K63	Thioredoxin
Arcve_1027	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
Arcve_1031	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
Arcve_1034	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
Arcve_1035	ENOG4105DZH	s-adenosylmethionine synthetase (EC 2.5.1.6)
Arcve_1040	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
Arcve_1050	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
Arcve_1051	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
Arcve_1052	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
Arcve_1062	ENOG4108RAC	Rubrerythrin
Arcve_1066	ENOG4105CUT	histidyl-tRNA synthetase
Arcve_1067	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
Arcve_1068	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
Arcve_1069	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
Arcve_1070	ENOG4105CHM	Aminotransferase
Arcve_1071	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
Arcve_1074	ENOG4105EAC	phosphoserine phosphatase
Arcve_1078	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
Arcve_1087	ENOG4105C83	adenylosuccinate lyase
Arcve_1091	ENOG4107XM9	(LipO)protein
Arcve_1092	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
Arcve_1093	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
Arcve_1094	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
Arcve_1096	ENOG4105CPN	adenine deaminase
Arcve_1097	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
Arcve_1098	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
Arcve_1107	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
Arcve_1115	ENOG4105DCC	Formylmethanofuran dehydrogenase subunit A
Arcve_1123	ENOG4105E8X	CO dehydrogenase acetyl-CoA synthase complex beta subunit
Arcve_1124	ENOG41080XS	Cobyrinic acid ac-diamide synthase
Arcve_1125	ENOG4106HYN	CO dehydrogenase acetyl-CoA synthase delta subunit
Arcve_1126	ENOG4105EYX	Acetyl-CoA decarbonylase synthase complex subunit gamma
Arcve_1130	ENOG4108IUQ	atp-dependent protease
Arcve_1135	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
Arcve_1137	ENOG4105CXT	aspartate transcarbamylase
Arcve_1138	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
Arcve_1139	ENOG4105EHU	Circadian clock protein KaiC
Arcve_1141	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
Arcve_1143	ENOG4105D64	Mechanosensitive ion channel
Arcve_1145	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
Arcve_1148	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
Arcve_1153	ENOG4105VCQ	rubredoxin
Arcve_1157	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
Arcve_1159	ENOG4108Y5D	Inherit from COG: cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
Arcve_1160	ENOG4105E0R	Deoxyhypusine synthase
Arcve_1161	ENOG4108JEJ	Pyruvoyl-dependent arginine decarboxylase
Arcve_1163	ENOG4107R3E	Citrate transporter
Arcve_1164	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
Arcve_1165	ENOG4105CY0	Metallo-Beta-Lactamase
Arcve_1168	ENOG41061GT	Aldolase
Arcve_1173	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
Arcve_1174	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
Arcve_1176	ENOG4105HMI	Membrane
Arcve_1177	ENOG4105BZU	Histidine kinase
Arcve_1179	ENOG4105D63	family UPF0324
Arcve_1183	ENOG4105HMI	Membrane
Arcve_1185	ENOG4105D63	family UPF0324
Arcve_1188	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
Arcve_1197	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
Arcve_1201	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
Arcve_1202	ENOG4105FIE	Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT) (By similarity)
Arcve_1207	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
Arcve_1208	ENOG4105DDK	oxidoreductase, beta subunit
Arcve_1209	ENOG4107TK4	histidinol-phosphate phosphatase
Arcve_1210	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
Arcve_1220	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
Arcve_1228	ENOG4105DF6	Fe-S oxidoreductase
Arcve_1232	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
Arcve_1233	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
Arcve_1234	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
Arcve_1245	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Arcve_1249	ENOG4105QAX	Iron-sulfur
Arcve_1254	ENOG4105DSE	periplasmic solute binding protein
Arcve_1255	ENOG4105DIK	(ABC) transporter
Arcve_1257	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
Arcve_1259	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
Arcve_1260	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
Arcve_1268	ENOG4105D06	uba thif-type nad fad binding protein
Arcve_1270	ENOG41080XS	Cobyrinic acid ac-diamide synthase
Arcve_1274	ENOG4105VXP	Protein of unknown function DUF86
Arcve_1275	ENOG4105DTD	Dehydrogenase
Arcve_1278	ENOG4105DZS	Phenylacetate-CoA ligase
Arcve_1279	ENOG4105F23	Fibronectin-binding protein
Arcve_1282	ENOG4105II7	pyrroline-5-carboxylate reductase
Arcve_1287	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
Arcve_1295	ENOG4105CBC	glutamate synthase
Arcve_1296	ENOG4105EYU	Glutamine amido-transferase
Arcve_1298	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
Arcve_1311	ENOG4108HMX	isocitrate dehydrogenase (NADP)
Arcve_1318	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
Arcve_1319	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
Arcve_1320	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
Arcve_1321	ENOG4105E66	phosphoriboisomerase A
Arcve_1323	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
Arcve_1325	ENOG4105CAQ	asparagine synthetase
Arcve_1327	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
Arcve_1333	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
Arcve_1335	ENOG4105C12	Phosphoribosylglycinamide synthetase
Arcve_1336	ENOG4105CJ3	phosphate transporter
Arcve_1346	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
Arcve_1349	ENOG4105CHV	Transcription elongation factor NusA
Arcve_1351	ENOG4107QR0	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Arcve_1352	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Arcve_1353	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Arcve_1358	ENOG4105C01	Dihydroxy-acid dehydratase
Arcve_1359	ENOG4107G87	m6 family metalloprotease domain protein
Arcve_1363	ENOG4105CX6	glutaminyL-tRNA synthetase
Arcve_1364	ENOG4108JEB	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
Arcve_1366	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
Arcve_1369	ENOG4105CKK	Glycosyl transferase, family 2
Arcve_1373	ENOG4105CJ1	ABC, transporter
Arcve_1382	ENOG41071TK	Uncharacterised protein family (UPF0150)
Arcve_1383	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
Arcve_1384	ENOG4105DBV	ornithine carbamoyltransferase
Arcve_1386	ENOG4105NBF	ammecr1 domain protein
Arcve_1390	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
Arcve_1393	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
Arcve_1396	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
Arcve_1404	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
Arcve_1405	ENOG4105IQJ	Involved in biosynthesis of the thiamine precursor thiazole (By similarity)
Arcve_1408	ENOG4105DX0	Hemolysin A
Arcve_1410	ENOG4105CP7	Triose-phosphate isomerase
Arcve_1411	ENOG4108P4C	Formaldehyde-activating enzyme
Arcve_1414	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
Arcve_1419	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
Arcve_1438	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
Arcve_1439	ENOG4108Y5D	Inherit from COG: cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
Arcve_1441	ENOG4107GFK	fumarate
Arcve_1446	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
Arcve_1449	ENOG41060IM	Heme exporter protein
Arcve_1455	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
Arcve_1456	ENOG4105CAS	nag kinase
Arcve_1460	ENOG4105CHU	acetyl-coa acetyltransferase
Arcve_1461	ENOG4107YTP	response regulator receiver protein
Arcve_1462	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
Arcve_1463	ENOG4105CBS	Chea signal transduction histidine kinase
Arcve_1465	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
Arcve_1466	ENOG4105BZU	Histidine kinase
Arcve_1478	ENOG41080XP	Cbs domain
Arcve_1479	ENOG41080XP	Cbs domain
Arcve_1481	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
Arcve_1482	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
Arcve_1483	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
Arcve_1486	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
Arcve_1491	ENOG4105DZS	Phenylacetate-CoA ligase
Arcve_1497	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
Arcve_1502	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
Arcve_1503	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
Arcve_1510	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
Arcve_1512	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
Arcve_1524	ENOG4105WMR	Protein CrcB homolog
Arcve_1525	ENOG4105KJJ	Uncharacterized ACR, COG1993
Arcve_1527	ENOG4105F7P	transcriptional regulator AsnC family
Arcve_1531	ENOG4105CK7	Sodium proline symporter
Arcve_1532	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
Arcve_1533	ENOG4107QX8	SPFH domain, Band 7 family protein
Arcve_1534	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
Arcve_1536	ENOG4105C8V	SAICAR synthetase
Arcve_1539	ENOG4105DTC	1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (air) carboxylase
Arcve_1540	ENOG4105C1A	potassium transporter peripheral membrane
Arcve_1545	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
Arcve_1546	ENOG4105DDK	oxidoreductase, beta subunit
Arcve_1547	ENOG4105C4C	beta-galactosidase
Arcve_1549	ENOG4108K7V	UPF0284 protein
Arcve_1557	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
Arcve_1559	ENOG4105EHG	Permease protein
Arcve_1560	ENOG4108F1U	ABC transporter
Arcve_1563	ENOG4105EWK	phytoene
Arcve_1564	ENOG4105DF6	Fe-S oxidoreductase
Arcve_1574	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
Arcve_1577	ENOG4107WCI	zn-dependent hydrolase of the beta-lactamase fold-like protein
Arcve_1580	ENOG4105CMQ	Chloride channel
Arcve_1585	ENOG4105CM2	brancheD-chain amino acid aminotransferase
Arcve_1587	ENOG4105D6E	homoserine dehydrogenase
Arcve_1590	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
Arcve_1592	ENOG4108UJD	30S ribosomal protein S9
Arcve_1595	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
Arcve_1596	ENOG4105CE9	30S ribosomal protein S2
Arcve_1597	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
Arcve_1601	ENOG4105EQR	Transposase IS116 IS110 IS902
Arcve_1603	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
Arcve_1605	ENOG4105D1F	ATP-binding protein
Arcve_1607	ENOG4105D1F	ATP-binding protein
Arcve_1610	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
Arcve_1611	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
Arcve_1614	ENOG4105C2X	Arabinose 5-phosphate isomerase
Arcve_1615	ENOG4105CSM	endonuclease III
Arcve_1616	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
Arcve_1617	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
Arcve_1618	ENOG4105I9Z	UPF0264 protein
Arcve_1621	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
Arcve_1622	ENOG4108Q27	Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate (By similarity)
Arcve_1623	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
Arcve_1629	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
Arcve_1640	ENOG4105C3U	ABC transporter
Arcve_1643	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
Arcve_1645	ENOG4107RNA	Nickel ABC transporter, periplasmic nickel-binding protein
Arcve_1649	ENOG4105CTK	cobaltochelatase, cobn subunit
Arcve_1652	ENOG4105EHG	Permease protein
Arcve_1655	ENOG4105FIK	Inherit from COG: dihydropteroate synthase
Arcve_1661	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
Arcve_1662	ENOG4105KST	dependent repressor
Arcve_1667	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
Arcve_1670	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
Arcve_1671	ENOG4105CD3	dihydroorotase
Arcve_1675	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
Arcve_1676	ENOG4105C0A	alcohol dehydrogenase
Arcve_1677	ENOG4105CMR	udp-glucose 4-epimerase
Arcve_1684	ENOG4105C5F	glutamine synthetase
Arcve_1691	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
Arcve_1693	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
Arcve_1694	ENOG4107QQM	Cysteine-rich domain
Arcve_1701	ENOG4107R56	PP-loop domain protein
Arcve_1704	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
Arcve_1711	ENOG4108UVJ	appr-1-p processing domain protein
Arcve_1715	ENOG4105DVH	amino acid
Arcve_1717	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
Arcve_1719	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
Arcve_1720	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
Arcve_1721	ENOG4105BZA	Phosphoglycerate kinase
Arcve_1723	ENOG4107XGZ	Hydrolase
Arcve_1727	ENOG4108PCN	EamA-like transporter family
Arcve_1732	ENOG4105CJ1	ABC, transporter
Arcve_1737	ENOG4105C8Q	Methyl-accepting chemotaxis
Arcve_1739	ENOG4105ZVY	2-oxoisovalerate dehydrogenase, E1 component beta subunit
Arcve_1741	ENOG4105DIW	FeS assembly protein SUFB
Arcve_1747	ENOG41066FR	extracellular solute-binding protein
Arcve_1749	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
Arcve_1750	ENOG4105F4R	Transcriptional regulator mode
Arcve_1755	ENOG41081FY	multiple antibiotic resistance (MarC)-related
Arcve_1757	ENOG4105C1J	atp-dependent rna helicase
Arcve_1767	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
Arcve_1771	ENOG4105C8J	)-transporter
Arcve_1773	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
Arcve_1779	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
Arcve_1785	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
Arcve_1786	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
Arcve_1789	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
Arcve_1790	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
Arcve_1791	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
Arcve_1792	ENOG4108T9Q	UPF0278 protein
Arcve_1795	ENOG4105EET	magnesium chelatase
Arcve_1797	ENOG4108V1U	phospholipid-binding protein
Arcve_1798	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
Arcve_1800	ENOG4105CKK	Glycosyl transferase, family 2
Arcve_1808	ENOG4108JJB	ABC transporter
Arcve_1811	ENOG4105CFT	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity)
Arcve_1812	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Arcve_1814	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
Arcve_1819	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
Arcve_1820	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
Arcve_1822	ENOG4108JEJ	Pyruvoyl-dependent arginine decarboxylase
Arcve_1823	ENOG4105C8T	Leucyl-tRNA synthetase
Arcve_1829	ENOG4108ZJI	phenylacetic acid degradation protein
Arcve_1832	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
Arcve_1833	ENOG4105C1G	acyl-Coa dehydrogenase
Arcve_1836	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
Arcve_1842	ENOG4105CQR	helicase
Arcve_1848	ENOG4107QMS	site-determining protein
Arcve_1852	ENOG4105CDH	Citrulline--aspartate ligase
Arcve_1854	ENOG4105E3S	small subunit
Arcve_1856	ENOG4108USZ	hydrogenase
Arcve_1858	ENOG4105VZ8	Transcriptional regulator
Arcve_1863	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Arcve_1864	ENOG4105CHR	reductase
Arcve_1876	ENOG4105DCI	Phosphohydrolase
Arcve_1878	ENOG4105DC7	peptidase M24
Arcve_1881	ENOG4108IUQ	atp-dependent protease
Arcve_1885	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
Arcve_1886	ENOG4107QZF	nitrite reductase NADPH large subunit
Arcve_1895	ENOG4108K16	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
Arcve_1897	ENOG4108VKG	metal-dependent hydrolase
Arcve_1898	ENOG4105DZR	Type I site-specific deoxyribonuclease
Arcve_1904	ENOG4107XZC	Restriction modification system DNA (Specificity
Arcve_1914	ENOG4105E8R	UPF0173 metal-dependent hydrolase
Arcve_1916	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
Arcve_1917	ENOG4105GRF	N-glycosylase DNA lyase
Arcve_1918	ENOG4108UQV	Membrane
Arcve_1931	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
Arcve_1932	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
Arcve_1936	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
Arcve_1937	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
Arcve_1939	ENOG4108IV0	ABC, transporter
Arcve_1940	ENOG4105C0Z	ABC transporter
Arcve_1942	ENOG4105C32	Amino acid ABC transporter (Permease)
Arcve_1944	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
Arcve_1948	ENOG4105PJW	Sulfite reductase dissimilatory-type beta subunit
Arcve_1949	ENOG4105CY1	sulfite reductase, dissimilatory-type alpha subunit
Arcve_1950	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
Arcve_1951	ENOG4105C22	threonyL-tRNA synthetase
Arcve_1953	ENOG4105FDK	ABC transporter
Arcve_1954	ENOG4105DJZ	UPF0182 protein
Arcve_1955	ENOG4105DG6	mannose-6-phosphate isomerase
Arcve_1961	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
Arcve_1962	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
Arcve_1964	ENOG4105CAS	nag kinase
Arcve_1969	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
Arcve_1977	ENOG4108JQ7	(ABC) transporter
Arcve_1978	ENOG4105C3U	ABC transporter
Arcve_1979	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
Arcve_1980	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
Arcve_1981	ENOG4105DEF	Extracellular solute-binding protein, family 5
Arcve_1982	ENOG4105DC1	bifunctional purine biosynthesis protein purh
Arcve_1983	ENOG4105C8Y	Acetylornithine aminotransferase
Arcve_1984	ENOG4107YZX	Universal stress protein
Arcve_1987	ENOG4105C3M	thioredoxin reductase
Arcve_1988	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
Arcve_1989	ENOG4105DA4	cytochrome c-type biogenesis protein
Arcve_1995	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Arcve_1997	ENOG4105CTP	PilT protein domain protein
Arcve_1998	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
Arcve_2004	ENOG4105BZU	Histidine kinase
Arcve_2006	ENOG4108MYP	Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four- carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
Arcve_2007	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
Arcve_2011	ENOG41068T5	Catalyzes the hydrolysis of methenyl-H(4)MPT( ) to 5- formyl-H(4)MPT (By similarity)
Arcve_2013	ENOG4108Y5D	Inherit from COG: cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
Arcve_2014	ENOG4105EW6	flavin reductase domain protein, FMN-binding
Arcve_2016	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
Arcve_2019	ENOG4105CD5	CoA-binding domain protein
Arcve_2030	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
Arcve_2031	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
Arcve_2032	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
Arcve_2034	ENOG4105CRQ	synthase (Component I)
Arcve_2035	ENOG4108I0Q	anthranilate phosphoribosyltransferase
Arcve_2036	ENOG4105DK0	Indole-3-glycerol phosphate synthase
Arcve_2041	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
Arcve_2047	ENOG4105CHU	acetyl-coa acetyltransferase
Arcve_2067	ENOG4105DBI	uridine monophosphokinase
Arcve_2079	ENOG4105C59	p-type ATPase
Arcve_2084	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
Arcve_2086	ENOG4105CIH	Imidazole acetol-phosphate transaminase
Arcve_2088	ENOG4107QRT	dEAD DEAH box helicase
Arcve_2096	ENOG4105BZN	citrate synthase
Arcve_2097	ENOG4105CHM	Aminotransferase
Arcve_2098	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
Arcve_2099	ENOG4105C6X	Major Facilitator
Arcve_2102	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
Arcve_2103	ENOG4105C8M	UPF0272 protein
Arcve_2105	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
Arcve_2109	ENOG4105CKX	Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP
Arcve_2115	ENOG4105EYH	Exonuclease
Arcve_2120	ENOG4107YZX	Universal stress protein
Arcve_2123	ENOG4108ZJT	translation initiation factor, Sui1
Arcve_2124	ENOG4108IUW	ABC transporter
Arcve_2127	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
Arcve_2134	ENOG4107QK3	aspartate-semialdehyde dehydrogenase (EC 1.2.1.11
Arcve_2139	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
Arcve_2140	ENOG4105W49	UPF0434 protein
Arcve_2141	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis