locus-tag	class	description
Arcve_0001	COG1372	Participates in initiation and elongation during chromosome replication
Arcve_0001	COG0305	Participates in initiation and elongation during chromosome replication
Arcve_0002	COG0003	Pfam Anion-transporting ATPase
Arcve_0004	COG1793	dna ligase
Arcve_0004	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
Arcve_0036	COG2409	Drug exporters of the RND superfamily
Arcve_0044	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
Arcve_0046	COG1522	sequence-specific DNA binding
Arcve_0047	COG0647	UMP catabolic process
Arcve_0049	COG0572	uridine kinase
Arcve_0051	COG2414	aldehyde ferredoxin oxidoreductase
Arcve_0059	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
Arcve_0064	COG3547	Transposase (IS116 IS110 IS902 family)
Arcve_0066	COG0352	thiamine-phosphate diphosphorylase activity
Arcve_0067	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Arcve_0071	COG1047	Peptidyl-prolyl cis-trans
Arcve_0074	COG1694	Mazg nucleotide pyrophosphohydrolase
Arcve_0077	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Arcve_0087	COG2131	deaminase
Arcve_0088	COG0084	hydrolase, TatD family'
Arcve_0090	COG2239	Acts as a magnesium transporter
Arcve_0091	COG0140	phosphoribosyl-ATP diphosphatase activity
Arcve_0093	COG0116	Belongs to the methyltransferase superfamily
Arcve_0093	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
Arcve_0094	COG0110	maltose O-acetyltransferase activity
Arcve_0096	COG0613	PHP domain protein
Arcve_0100	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Arcve_0100	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
Arcve_0105	COG4962	Type ii secretion system protein e
Arcve_0113	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
Arcve_0115	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
Arcve_0117	COG0142	geranyltranstransferase activity
Arcve_0125	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
Arcve_0127	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
Arcve_0138	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
Arcve_0141	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
Arcve_0143	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
Arcve_0146	COG0589	response to stress
Arcve_0152	COG0531	amino acid
Arcve_0161	COG0375	protein maturation
Arcve_0165	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
Arcve_0166	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
Arcve_0171	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
Arcve_0173	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
Arcve_0175	COG0018	arginyl-trna synthetase
Arcve_0176	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
Arcve_0180	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
Arcve_0186	COG5002	protein histidine kinase activity
Arcve_0187	COG3290	protein histidine kinase activity
Arcve_0189	COG3290	protein histidine kinase activity
Arcve_0190	COG2197	response regulator
Arcve_0195	COG2860	membrane
Arcve_0203	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Arcve_0208	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
Arcve_0209	COG1793	dna ligase
Arcve_0209	COG3285	dna ligase
Arcve_0212	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
Arcve_0215	COG0109	protoheme IX farnesyltransferase activity
Arcve_0219	COG0314	molybdopterin synthase activity
Arcve_0221	COG0864	Transcriptional regulator
Arcve_0222	COG2088	sporulation resulting in formation of a cellular spore
Arcve_0223	COG0017	Asparaginyl-tRNA synthetase
Arcve_0224	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
Arcve_0226	COG3118	belongs to the thioredoxin family
Arcve_0227	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
Arcve_0228	COG0432	Pfam Uncharacterised protein family UPF0047
Arcve_0232	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
Arcve_0239	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
Arcve_0241	COG4399	Belongs to the UPF0754 family
Arcve_0242	COG0303	'Molybdopterin
Arcve_0243	COG0303	'Molybdopterin
Arcve_0248	COG1122	ATPase activity
Arcve_0249	COG1268	BioY protein
Arcve_0250	COG1522	sequence-specific DNA binding
Arcve_0258	COG1131	(ABC) transporter
Arcve_0263	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Arcve_0266	COG1683	Conserved Protein
Arcve_0267	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Arcve_0269	COG0252	asparaginase activity
Arcve_0270	COG0165	Argininosuccinate lyase
Arcve_0273	COG0358	DNA primase activity
Arcve_0276	COG0076	glutamate decarboxylase activity
Arcve_0277	COG0746	molybdenum cofactor guanylyltransferase activity
Arcve_0278	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Arcve_0280	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Arcve_0283	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
Arcve_0287	COG0436	Aminotransferase
Arcve_0289	COG3335	DDE superfamily endonuclease
Arcve_0297	COG1269	ATP hydrolysis coupled proton transport
Arcve_0302	COG1527	subunit (C
Arcve_0304	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
Arcve_0305	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
Arcve_0308	COG0456	acetyltransferase
Arcve_0309	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Arcve_0322	COG0857	belongs to the CobB CobQ family
Arcve_0323	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
Arcve_0323	COG1328	CTP reductase activity
Arcve_0325	COG0602	queuosine metabolic process
Arcve_0327	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Arcve_0328	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Arcve_0330	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Arcve_0332	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
Arcve_0332	COG0517	IMP dehydrogenase activity
Arcve_0333	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
Arcve_0336	COG2037	Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT)
Arcve_0345	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
Arcve_0347	COG0840	transmembrane signaling receptor activity
Arcve_0347	COG3290	protein histidine kinase activity
Arcve_0354	COG0154	amidase activity
Arcve_0355	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Arcve_0358	COG1444	tRNA N-acetyltransferase activity
Arcve_0362	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
Arcve_0368	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
Arcve_0370	COG0489	protein tyrosine kinase activity
Arcve_0372	COG1229	Formylmethanofuran dehydrogenase subunit A
Arcve_0376	COG0517	IMP dehydrogenase activity
Arcve_0380	COG4191	Histidine kinase
Arcve_0386	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
Arcve_0396	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
Arcve_0398	COG0688	phosphatidylethanolamine metabolic process
Arcve_0399	COG1183	phosphatidylcholine synthase activity
Arcve_0403	COG1720	tRNA m6t6A37 methyltransferase activity
Arcve_0406	COG0436	Aminotransferase
Arcve_0408	COG1489	DNA binding
Arcve_0410	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
Arcve_0415	COG0012	GTP binding
Arcve_0420	COG2046	Belongs to the sulfate adenylyltransferase family
Arcve_0424	COG1233	COG1233 Phytoene dehydrogenase and related
Arcve_0425	COG0446	pyridine nucleotide-disulphide oxidoreductase
Arcve_0430	COG1830	Aldolase
Arcve_0431	COG1465	3-dehydroquinate synthase
Arcve_0432	COG0710	3-dehydroquinate dehydratase activity
Arcve_0433	COG1605	Chorismate mutase
Arcve_0433	COG0077	Prephenate dehydratase
Arcve_0434	COG1378	Sugar-specific transcriptional regulator TrmB
Arcve_0435	COG1131	(ABC) transporter
Arcve_0436	COG0842	Transport permease protein
Arcve_0443	COG2104	thiamine diphosphate biosynthetic process
Arcve_0451	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
Arcve_0452	COG1342	Belongs to the UPF0251 family
Arcve_0456	COG0105	UTP biosynthetic process
Arcve_0457	COG3170	Tfp pilus assembly protein FimV
Arcve_0457	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
Arcve_0461	COG2226	methyltransferase
Arcve_0470	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Arcve_0502	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
Arcve_0503	COG0113	porphobilinogen synthase activity
Arcve_0504	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
Arcve_0505	COG0181	hydroxymethylbilane synthase activity
Arcve_0509	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Arcve_0510	COG0489	protein tyrosine kinase activity
Arcve_0512	COG0531	amino acid
Arcve_0513	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
Arcve_0514	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
Arcve_0515	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Arcve_0517	COG0501	Belongs to the peptidase M48B family
Arcve_0518	COG0371	Dehydrogenase
Arcve_0522	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
Arcve_0523	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
Arcve_0526	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Arcve_0528	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
Arcve_0535	COG0425	Belongs to the sulfur carrier protein TusA family
Arcve_0541	COG0442	prolyl-tRNA aminoacylation
Arcve_0551	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
Arcve_0553	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
Arcve_0562	COG0463	Glycosyl transferase, family 2
Arcve_0564	COG0673	inositol 2-dehydrogenase activity
Arcve_0566	COG0438	transferase activity, transferring glycosyl groups
Arcve_0580	COG1793	dna ligase
Arcve_0586	COG0644	oxidoreductase
Arcve_0587	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Arcve_0589	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Arcve_0592	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Arcve_0594	COG0517	IMP dehydrogenase activity
Arcve_0594	COG1994	Peptidase M50
Arcve_0596	COG0730	response to heat
Arcve_0597	COG0473	3-isopropylmalate dehydrogenase activity
Arcve_0598	COG1355	regulation of microtubule-based process
Arcve_0599	COG0083	homoserine kinase activity
Arcve_0601	COG1304	FMN binding
Arcve_0611	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
Arcve_0615	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
Arcve_0616	COG0589	response to stress
Arcve_0617	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
Arcve_0618	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
Arcve_0620	COG2255	four-way junction helicase activity
Arcve_0621	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Arcve_0622	COG1201	RNA secondary structure unwinding
Arcve_0623	COG0446	pyridine nucleotide-disulphide oxidoreductase
Arcve_0624	COG1573	uracil-dna glycosylase
Arcve_0628	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
Arcve_0629	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
Arcve_0631	COG2217	Heavy metal translocating P-type atpase
Arcve_0632	COG0640	Transcriptional regulator
Arcve_0638	COG1592	Rubrerythrin
Arcve_0638	COG1773	rubredoxin
Arcve_0639	COG1271	oxidase subunit
Arcve_0648	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Arcve_0650	COG1592	Rubrerythrin
Arcve_0651	COG0450	alkyl hydroperoxide reductase
Arcve_0688	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Arcve_0690	COG0004	ammonium transporteR
Arcve_0694	COG0490	domain, Protein
Arcve_0694	COG2985	domain, Protein
Arcve_0695	COG0475	glutathione-regulated potassium exporter activity
Arcve_0696	COG0004	ammonium transporteR
Arcve_0698	COG0426	domain, Protein
Arcve_0700	COG0519	Catalyzes the synthesis of GMP from XMP
Arcve_0700	COG0518	GMP synthase (glutamine-hydrolyzing) activity
Arcve_0701	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Arcve_0702	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Arcve_0707	COG0393	Putative heavy-metal-binding
Arcve_0711	COG0438	transferase activity, transferring glycosyl groups
Arcve_0716	COG1234	tRNA 3'-trailer cleavage
Arcve_0717	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Arcve_0720	COG0437	4 iron, 4 sulfur cluster binding
Arcve_0721	COG3383	formate dehydrogenase (NAD+) activity
Arcve_0721	COG0243	molybdopterin cofactor binding
Arcve_0725	COG0358	DNA primase activity
Arcve_0736	COG1598	PFAM Uncharacterised protein family UPF0150
Arcve_0746	COG0525	valine-tRNA ligase activity
Arcve_0747	COG0179	Fumarylacetoacetate (FAA) hydrolase
Arcve_0749	COG1254	Belongs to the acylphosphatase family
Arcve_0753	COG0569	domain protein
Arcve_0754	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Arcve_0758	COG0343	queuine tRNA-ribosyltransferase activity
Arcve_0765	COG1181	Belongs to the D-alanine--D-alanine ligase family
Arcve_0768	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Arcve_0769	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
Arcve_0772	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Arcve_0773	COG1203	CRISPR-associated helicase, Cas3
Arcve_0778	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
Arcve_0779	COG1518	maintenance of DNA repeat elements
Arcve_0782	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
Arcve_0786	COG1850	ribulose-bisphosphate carboxylase activity
Arcve_0789	COG0528	UMP kinase activity
Arcve_0795	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Arcve_0796	COG1013	pyruvate-flavodoxin oxidoreductase activity
Arcve_0797	COG0674	pyruvate-flavodoxin oxidoreductase activity
Arcve_0800	COG0493	'glutamate synthase
Arcve_0800	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
Arcve_0804	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
Arcve_0806	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
Arcve_0808	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Arcve_0813	COG1720	tRNA m6t6A37 methyltransferase activity
Arcve_0814	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
Arcve_0822	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Arcve_0823	COG1940	carbohydrate kinase activity
Arcve_0828	COG2875	Belongs to the precorrin methyltransferase family
Arcve_0833	COG0310	cobalt ion transport
Arcve_0835	COG3335	DDE superfamily endonuclease
Arcve_0848	COG0539	negative regulation of cytoplasmic translation
Arcve_0853	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
Arcve_0854	COG0515	serine threonine protein kinase
Arcve_0860	COG4637	Psort location Cytoplasmic, score
Arcve_0861	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
Arcve_0862	COG0758	DNA mediated transformation
Arcve_0865	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
Arcve_0866	COG0704	Plays a role in the regulation of phosphate uptake
Arcve_0867	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Arcve_0868	COG0573	inorganic phosphate transmembrane transporter activity
Arcve_0869	COG0573	inorganic phosphate transmembrane transporter activity
Arcve_0870	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
Arcve_0872	COG1335	isochorismatase
Arcve_0874	COG3335	DDE superfamily endonuclease
Arcve_0887	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Arcve_0891	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Arcve_0895	COG3335	DDE superfamily endonuclease
Arcve_0902	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
Arcve_0905	COG1980	fructose-bisphosphate aldolase activity
Arcve_0906	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
Arcve_0908	COG1110	DNA topoisomerase II activity
Arcve_0909	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
Arcve_0917	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Arcve_0919	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
Arcve_0920	COG0284	orotidine-5'-phosphate decarboxylase activity
Arcve_0921	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
Arcve_0922	COG1363	Peptidase, m42
Arcve_0927	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
Arcve_0927	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
Arcve_0929	COG1227	inorganic diphosphatase activity
Arcve_0930	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Arcve_0930	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Arcve_0931	COG1058	Belongs to the CinA family
Arcve_0931	COG1546	Belongs to the CinA family
Arcve_0940	COG0535	radical SAM domain protein
Arcve_0942	COG0081	regulation of translation
Arcve_0943	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
Arcve_0951	COG0720	synthase
Arcve_0952	COG0602	queuosine metabolic process
Arcve_0953	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
Arcve_0956	COG0519	Catalyzes the synthesis of GMP from XMP
Arcve_0956	COG0518	GMP synthase (glutamine-hydrolyzing) activity
Arcve_0958	COG1136	(ABC) transporter
Arcve_0960	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
Arcve_0962	COG0201	protein transport
Arcve_0965	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
Arcve_0969	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
Arcve_0970	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
Arcve_0972	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
Arcve_0974	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
Arcve_0975	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
Arcve_0976	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
Arcve_0978	COG0255	Belongs to the universal ribosomal protein uL29 family
Arcve_0979	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
Arcve_0980	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
Arcve_0981	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
Arcve_0982	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Arcve_0983	COG0089	rRNA binding
Arcve_0985	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
Arcve_0988	COG0066	3-isopropylmalate dehydratase activity
Arcve_0991	COG0215	cysteine-tRNA ligase activity
Arcve_0993	COG0383	alpha-mannosidase activity
Arcve_0994	COG3769	mannosylglycerate metabolic process
Arcve_0998	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Arcve_1000	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
Arcve_1001	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Arcve_1004	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Arcve_1007	COG0559	Belongs to the binding-protein-dependent transport system permease family
Arcve_1024	COG3118	belongs to the thioredoxin family
Arcve_1027	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
Arcve_1028	COG1836	PFAM Integral membrane protein DUF92
Arcve_1031	COG1185	polyribonucleotide nucleotidyltransferase activity
Arcve_1034	COG0218	Necessary for normal cell division and for the maintenance of normal septation
Arcve_1035	COG1812	S-adenosylmethionine synthetase (AdoMet synthetase)
Arcve_1039	COG0583	DNA-binding transcription factor activity
Arcve_1040	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Arcve_1050	COG1185	polyribonucleotide nucleotidyltransferase activity
Arcve_1051	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
Arcve_1052	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
Arcve_1062	COG1592	Rubrerythrin
Arcve_1067	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Arcve_1068	COG0051	transcription antitermination factor activity, RNA binding
Arcve_1069	COG1234	tRNA 3'-trailer cleavage
Arcve_1070	COG0436	Aminotransferase
Arcve_1074	COG0560	Phosphoserine phosphatase
Arcve_1074	COG3830	Belongs to the UPF0237 family
Arcve_1078	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
Arcve_1085	COG4109	DRTGG domain
Arcve_1087	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
Arcve_1091	COG1073	alpha beta
Arcve_1092	COG0563	adenylate kinase activity
Arcve_1093	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
Arcve_1094	COG0402	S-adenosylhomocysteine deaminase activity
Arcve_1096	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
Arcve_1098	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Arcve_1107	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
Arcve_1115	COG1229	Formylmethanofuran dehydrogenase subunit A
Arcve_1130	COG1067	ATP-dependent peptidase activity
Arcve_1130	COG0470	DNA polymerase III
Arcve_1135	COG0402	S-adenosylhomocysteine deaminase activity
Arcve_1137	COG0540	Belongs to the ATCase OTCase family
Arcve_1138	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
Arcve_1139	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
Arcve_1141	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Arcve_1143	COG0668	transmembrane transport
Arcve_1145	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Arcve_1146	COG1305	Transglutaminase-like
Arcve_1148	COG0714	Associated with various cellular activities
Arcve_1153	COG1773	rubredoxin
Arcve_1157	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
Arcve_1159	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Arcve_1159	COG1213	nucleotidyl transferase
Arcve_1160	COG1899	peptidyl-lysine modification to peptidyl-hypusine
Arcve_1161	COG1945	arginine decarboxylase activity
Arcve_1163	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
Arcve_1164	COG1763	Mo-molybdopterin cofactor biosynthetic process
Arcve_1165	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
Arcve_1166	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
Arcve_1168	COG1830	Aldolase
Arcve_1173	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Arcve_1174	COG0047	phosphoribosylformylglycinamidine synthase activity
Arcve_1176	COG2855	membrane
Arcve_1177	COG5002	protein histidine kinase activity
Arcve_1177	COG5001	Diguanylate cyclase
Arcve_1177	COG3447	MASE1 domain protein
Arcve_1179	COG2855	membrane
Arcve_1183	COG2855	membrane
Arcve_1185	COG2855	membrane
Arcve_1188	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Arcve_1192	COG0561	phosphatase activity
Arcve_1197	COG0109	protoheme IX farnesyltransferase activity
Arcve_1201	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
Arcve_1202	COG2037	Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT)
Arcve_1207	COG0674	pyruvate-flavodoxin oxidoreductase activity
Arcve_1208	COG1013	pyruvate-flavodoxin oxidoreductase activity
Arcve_1209	COG0483	inositol monophosphate 1-phosphatase activity
Arcve_1210	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
Arcve_1214	COG0010	Belongs to the arginase family
Arcve_1220	COG0297	glycogen (starch) synthase activity
Arcve_1228	COG2181	nitrate reductase activity
Arcve_1228	COG0247	lactate metabolic process
Arcve_1232	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
Arcve_1233	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
Arcve_1235	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
Arcve_1245	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Arcve_1249	COG0437	4 iron, 4 sulfur cluster binding
Arcve_1254	COG0803	Belongs to the bacterial solute-binding protein 9 family
Arcve_1255	COG1121	(ABC) transporter
Arcve_1257	COG0066	3-isopropylmalate dehydratase activity
Arcve_1259	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
Arcve_1260	COG0009	L-threonylcarbamoyladenylate synthase
Arcve_1268	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
Arcve_1274	COG2361	Protein of unknown function DUF86
Arcve_1275	COG1028	Short-chain dehydrogenase reductase Sdr
Arcve_1278	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
Arcve_1282	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
Arcve_1283	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
Arcve_1287	COG2264	protein methyltransferase activity
Arcve_1295	COG0069	glutamate synthase activity
Arcve_1296	COG0067	glutamate synthase
Arcve_1298	COG0037	tRNA processing
Arcve_1305	COG1215	transferase activity, transferring glycosyl groups
Arcve_1311	COG0538	isocitrate dehydrogenase activity
Arcve_1312	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
Arcve_1318	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
Arcve_1319	COG0482	sulfurtransferase activity
Arcve_1320	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
Arcve_1321	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
Arcve_1323	COG0187	DNA topoisomerase II activity
Arcve_1325	COG0367	asparagine synthase
Arcve_1327	COG1335	isochorismatase
Arcve_1333	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
Arcve_1336	COG0306	phosphate transporter
Arcve_1346	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Arcve_1349	COG0195	Participates in both transcription termination and antitermination
Arcve_1351	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
Arcve_1352	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
Arcve_1358	COG0129	dihydroxy-acid dehydratase activity
Arcve_1359	COG4412	M6 family metalloprotease domain protein
Arcve_1359	COG3291	Pkd domain containing protein
Arcve_1364	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
Arcve_1365	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
Arcve_1366	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Arcve_1369	COG0463	Glycosyl transferase, family 2
Arcve_1373	COG1131	(ABC) transporter
Arcve_1382	COG1598	PFAM Uncharacterised protein family UPF0150
Arcve_1383	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
Arcve_1384	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
Arcve_1386	COG2078	PFAM AMMECR1 domain protein
Arcve_1390	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Arcve_1391	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Arcve_1393	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
Arcve_1396	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
Arcve_1398	COG1196	nuclear chromosome segregation
Arcve_1404	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
Arcve_1405	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
Arcve_1408	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
Arcve_1410	COG0149	triose-phosphate isomerase activity
Arcve_1411	COG1795	PFAM Formaldehyde-activating enzyme (Fae)
Arcve_1414	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
Arcve_1414	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
Arcve_1419	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Arcve_1421	COG0440	acetolactate synthase activity
Arcve_1434	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Arcve_1438	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Arcve_1439	COG1213	nucleotidyl transferase
Arcve_1439	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Arcve_1446	COG0301	tRNA thio-modification
Arcve_1449	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Arcve_1455	COG0805	protein transport
Arcve_1456	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
Arcve_1460	COG0183	Belongs to the thiolase family
Arcve_1461	COG2201	protein-glutamate methylesterase activity
Arcve_1462	COG2201	protein-glutamate methylesterase activity
Arcve_1463	COG2198	Histidine kinase
Arcve_1463	COG0643	Histidine kinase
Arcve_1465	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
Arcve_1466	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
Arcve_1472	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
Arcve_1478	COG0517	IMP dehydrogenase activity
Arcve_1479	COG0517	IMP dehydrogenase activity
Arcve_1481	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
Arcve_1482	COG0301	tRNA thio-modification
Arcve_1483	COG0585	pseudouridine synthase activity
Arcve_1485	COG0011	TIGRFAM Protein of
Arcve_1486	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
Arcve_1491	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
Arcve_1497	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
Arcve_1498	COG0312	modulator of DNA gyrase
Arcve_1502	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Arcve_1503	COG0322	excinuclease ABC activity
Arcve_1510	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
Arcve_1512	COG0574	Belongs to the PEP-utilizing enzyme family
Arcve_1512	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Arcve_1524	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
Arcve_1525	COG1993	acr, cog1993
Arcve_1526	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Arcve_1527	COG1522	sequence-specific DNA binding
Arcve_1531	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Arcve_1532	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
Arcve_1533	COG0330	HflC and HflK could
Arcve_1534	COG0439	Biotin carboxylase
Arcve_1536	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
Arcve_1538	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
Arcve_1539	COG1691	(AIR) carboxylase
Arcve_1540	COG0569	domain protein
Arcve_1545	COG0674	pyruvate-flavodoxin oxidoreductase activity
Arcve_1546	COG1013	pyruvate-flavodoxin oxidoreductase activity
Arcve_1549	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
Arcve_1552	COG3335	DDE superfamily endonuclease
Arcve_1557	COG0101	tRNA pseudouridine synthase activity
Arcve_1560	COG1120	ATPase activity
Arcve_1564	COG2181	nitrate reductase activity
Arcve_1564	COG0247	lactate metabolic process
Arcve_1567	COG1053	succinate dehydrogenase
Arcve_1570	COG3259	Nickel-dependent hydrogenase
Arcve_1577	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
Arcve_1585	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Arcve_1587	COG0460	homoserine dehydrogenase
Arcve_1590	COG0200	Binds to the 23S rRNA
Arcve_1592	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Arcve_1595	COG0148	phosphopyruvate hydratase activity
Arcve_1596	COG0052	Belongs to the universal ribosomal protein uS2 family
Arcve_1597	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
Arcve_1601	COG3547	Transposase (IS116 IS110 IS902 family)
Arcve_1603	COG1185	polyribonucleotide nucleotidyltransferase activity
Arcve_1605	COG0489	protein tyrosine kinase activity
Arcve_1607	COG0489	protein tyrosine kinase activity
Arcve_1610	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
Arcve_1611	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
Arcve_1614	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
Arcve_1614	COG0517	IMP dehydrogenase activity
Arcve_1615	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Arcve_1617	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
Arcve_1618	COG1891	lyase activity
Arcve_1621	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
Arcve_1622	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
Arcve_1623	COG0157	Belongs to the NadC ModD family
Arcve_1629	COG0805	protein transport
Arcve_1639	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
Arcve_1640	COG0444	Belongs to the ABC transporter superfamily
Arcve_1645	COG0747	negative chemotaxis
Arcve_1652	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Arcve_1653	COG4607	ABC-type enterochelin transport system periplasmic component
Arcve_1662	COG1321	iron dependent repressor
Arcve_1667	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
Arcve_1670	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
Arcve_1671	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Arcve_1675	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
Arcve_1676	COG1454	alcohol dehydrogenase
Arcve_1677	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Arcve_1693	COG1797	cobyrinic acid a,c-diamide synthase activity
Arcve_1694	COG0247	lactate metabolic process
Arcve_1701	COG0037	tRNA processing
Arcve_1704	COG2264	protein methyltransferase activity
Arcve_1711	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
Arcve_1715	COG0531	amino acid
Arcve_1717	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Arcve_1719	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
Arcve_1719	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
Arcve_1720	COG0163	prenyltransferase activity
Arcve_1721	COG0126	phosphoglycerate kinase activity
Arcve_1723	COG0546	phosphoglycolate phosphatase activity
Arcve_1725	COG0434	BtpA family
Arcve_1727	COG0697	spore germination
Arcve_1732	COG1131	(ABC) transporter
Arcve_1735	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Arcve_1737	COG0840	transmembrane signaling receptor activity
Arcve_1739	COG1598	PFAM Uncharacterised protein family UPF0150
Arcve_1741	COG0719	Fe-S assembly protein
Arcve_1747	COG0725	ABC transporter, periplasmic molybdate-binding protein
Arcve_1749	COG3842	ATPase activity
Arcve_1750	COG2005	Transcriptional regulator
Arcve_1755	COG2095	MarC family integral membrane protein
Arcve_1757	COG0513	Belongs to the DEAD box helicase family
Arcve_1767	COG0552	protein localization to endoplasmic reticulum
Arcve_1771	COG0733	neurotransmitter:sodium symporter activity
Arcve_1773	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Arcve_1773	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Arcve_1779	COG1492	cobalamin metabolic process
Arcve_1785	COG0131	Imidazoleglycerol-phosphate dehydratase
Arcve_1785	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
Arcve_1786	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
Arcve_1789	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
Arcve_1790	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Arcve_1790	COG0301	tRNA thio-modification
Arcve_1791	COG0315	cyclic pyranopterin monophosphate synthase activity
Arcve_1795	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
Arcve_1796	COG3431	PFAM Phosphate-starvation-inducible E
Arcve_1797	COG1881	PFAM PEBP family protein
Arcve_1798	COG1469	GTP cyclohydrolase I activity
Arcve_1800	COG0463	Glycosyl transferase, family 2
Arcve_1804	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Arcve_1808	COG1122	ATPase activity
Arcve_1811	COG0310	cobalt ion transport
Arcve_1812	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Arcve_1814	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Arcve_1819	COG0543	2 iron, 2 sulfur cluster binding
Arcve_1820	COG0167	dihydroorotate dehydrogenase activity
Arcve_1821	COG1794	racemase activity, acting on amino acids and derivatives
Arcve_1822	COG1945	arginine decarboxylase activity
Arcve_1823	COG0495	leucyl-tRNA aminoacylation
Arcve_1829	COG2050	protein possibly involved in aromatic compounds catabolism
Arcve_1832	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Arcve_1833	COG1960	acyl-CoA dehydrogenase activity
Arcve_1836	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
Arcve_1842	COG4581	dead DEAH box helicase
Arcve_1848	COG2894	cell division
Arcve_1852	COG0137	argininosuccinate synthase activity
Arcve_1854	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
Arcve_1855	COG3259	Nickel-dependent hydrogenase
Arcve_1856	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
Arcve_1858	COG1476	TRANSCRIPTIONal
Arcve_1863	COG0731	radical SAM domain protein
Arcve_1863	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Arcve_1864	COG1028	Short-chain dehydrogenase reductase Sdr
Arcve_1876	COG1078	dGTPase activity
Arcve_1878	COG0006	proline dipeptidase activity
Arcve_1881	COG0470	DNA polymerase III
Arcve_1881	COG1067	ATP-dependent peptidase activity
Arcve_1886	COG2146	nitrite reductase [NAD(P)H] activity
Arcve_1886	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Arcve_1895	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
Arcve_1897	COG1451	nucleotide metabolic process
Arcve_1898	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
Arcve_1904	COG0732	type I restriction modification DNA specificity domain
Arcve_1914	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
Arcve_1916	COG2414	aldehyde ferredoxin oxidoreductase
Arcve_1917	COG1059	Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine 7-oxoG) from DNA. Also nicks DNA at apurinic apyrimidinic sites (AP sites)
Arcve_1918	COG1811	Na channel or pump
Arcve_1920	COG3335	DDE superfamily endonuclease
Arcve_1931	COG1136	(ABC) transporter
Arcve_1932	COG1136	(ABC) transporter
Arcve_1932	COG0577	efflux transmembrane transporter activity
Arcve_1936	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
Arcve_1937	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Arcve_1940	COG0411	ABC transporter
Arcve_1942	COG0559	Belongs to the binding-protein-dependent transport system permease family
Arcve_1944	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
Arcve_1948	COG2221	Nitrite and sulphite reductase 4Fe-4S
Arcve_1949	COG2221	Nitrite and sulphite reductase 4Fe-4S
Arcve_1950	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Arcve_1953	COG1121	(ABC) transporter
Arcve_1954	COG1615	UPF0182 protein
Arcve_1955	COG1482	cell wall glycoprotein biosynthetic process
Arcve_1964	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
Arcve_1969	COG0519	Catalyzes the synthesis of GMP from XMP
Arcve_1969	COG0518	GMP synthase (glutamine-hydrolyzing) activity
Arcve_1971	COG3335	DDE superfamily endonuclease
Arcve_1977	COG4608	Belongs to the ABC transporter superfamily
Arcve_1978	COG0444	Belongs to the ABC transporter superfamily
Arcve_1980	COG0601	transmembrane transport
Arcve_1981	COG0747	negative chemotaxis
Arcve_1982	COG0138	bifunctional purine biosynthesis protein purh
Arcve_1983	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Arcve_1984	COG0589	response to stress
Arcve_1987	COG0492	ferredoxin-NADP+ reductase activity
Arcve_1988	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
Arcve_1989	COG1138	Cytochrome C-type biogenesis protein
Arcve_1995	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Arcve_1997	COG4956	integral membrane protein (PIN domain superfamily)
Arcve_1998	COG0140	phosphoribosyl-ATP diphosphatase activity
Arcve_1998	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
Arcve_2004	COG0004	ammonium transporteR
Arcve_2006	COG1892	Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four- carbon dicarboxylic acid source for the tricarboxylic acid cycle
Arcve_2007	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
Arcve_2007	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
Arcve_2011	COG3252	Catalyzes the hydrolysis of methenyl-H(4)MPT( ) to 5- formyl-H(4)MPT
Arcve_2013	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Arcve_2013	COG1213	nucleotidyl transferase
Arcve_2014	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Arcve_2016	COG0521	Mo-molybdopterin cofactor biosynthetic process
Arcve_2020	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
Arcve_2031	COG0133	tryptophan synthase activity
Arcve_2033	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
Arcve_2033	COG0512	Glutamine amidotransferase of anthranilate synthase
Arcve_2035	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Arcve_2036	COG0134	indole-3-glycerol-phosphate synthase activity
Arcve_2041	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
Arcve_2047	COG0183	Belongs to the thiolase family
Arcve_2067	COG0572	uridine kinase
Arcve_2079	COG2217	Heavy metal translocating P-type atpase
Arcve_2084	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
Arcve_2086	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Arcve_2088	COG1201	RNA secondary structure unwinding
Arcve_2092	COG1418	mRNA catabolic process
Arcve_2096	COG0372	Belongs to the citrate synthase family
Arcve_2097	COG0436	Aminotransferase
Arcve_2098	COG0019	diaminopimelate decarboxylase activity
Arcve_2099	COG2814	Major facilitator Superfamily
Arcve_2102	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Arcve_2103	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
Arcve_2105	COG0543	2 iron, 2 sulfur cluster binding
Arcve_2109	COG0430	RNA-3'-phosphate cyclase activity
Arcve_2115	COG0419	ATPase involved in DNA repair
Arcve_2120	COG0589	response to stress
Arcve_2123	COG0023	Translation Initiation Factor
Arcve_2124	COG4555	ABC transporter
Arcve_2127	COG0442	prolyl-tRNA aminoacylation
Arcve_2139	COG0504	CTP synthase activity
Arcve_2141	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP