locus-tag	class	description
AA314_00007	ENOG4108HMN	Caspase domain
AA314_00009	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
AA314_00027	ENOG4106A3M	Cytochrome p-450
AA314_00028	ENOG4106A3M	Cytochrome p-450
AA314_00035	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
AA314_00037	ENOG4105CJ1	ABC, transporter
AA314_00039	ENOG4105CJ1	ABC, transporter
AA314_00040	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
AA314_00055	ENOG4108JUA	Transcriptional regulator
AA314_00069	ENOG4108W3Q	Transcriptional regulator
AA314_00070	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AA314_00073	ENOG4108V5V	Serine Threonine protein kinase
AA314_00081	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
AA314_00082	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
AA314_00084	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
AA314_00085	ENOG4105BZU	Histidine kinase
AA314_00087	ENOG4105BZU	Histidine kinase
AA314_00094	ENOG4107R5B	glutamine synthetase
AA314_00095	ENOG4108JUA	Transcriptional regulator
AA314_00099	ENOG4105DHF	Membrane
AA314_00102	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
AA314_00113	ENOG4107SM8	Adenylate Guanylate cyclase
AA314_00119	ENOG4105BZU	Histidine kinase
AA314_00121	ENOG4106RGN	vegetative protein
AA314_00129	ENOG4105CNF	WD-40 repeat protein
AA314_00132	ENOG4108TGY	Glutathione S-transferase
AA314_00133	ENOG4105EYM	Major Facilitator superfamily
AA314_00136	ENOG4105C2C	drug resistance transporter, Bcr CflA
AA314_00137	ENOG4105BZU	Histidine kinase
AA314_00158	ENOG4105EXG	Transcriptional regulator
AA314_00166	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
AA314_00167	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
AA314_00168	ENOG4107W7X	Aldolase
AA314_00170	ENOG4105ES5	Histidine kinase
AA314_00173	ENOG4105D0U	Arsenite-activated ATPase (ArsA)
AA314_00174	ENOG41080XP	Cbs domain
AA314_00180	ENOG41068KG	domain protein
AA314_00183	ENOG4105BZU	Histidine kinase
AA314_00187	ENOG4108UVJ	appr-1-p processing domain protein
AA314_00193	ENOG4107ZBH	radical SAM domain protein
AA314_00195	ENOG4105F8J	Adenylate Guanylate cyclase
AA314_00197	ENOG4105F8J	Adenylate Guanylate cyclase
AA314_00207	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
AA314_00208	ENOG4106RGN	vegetative protein
AA314_00211	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
AA314_00212	ENOG41062BK	proline dehydrogenase
AA314_00220	ENOG4105DC8	reductase
AA314_00224	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
AA314_00225	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
AA314_00230	ENOG4105PDP	Short chain dehydrogenase
AA314_00244	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
AA314_00246	ENOG4105CQB	FAD linked oxidase domain protein
AA314_00248	ENOG4107QPV	Serine Threonine protein kinase
AA314_00253	ENOG4108UZE	carboxy-peptidase
AA314_00255	ENOG4107IFA	Lipase (EC 3.1.1.3)
AA314_00257	ENOG4105CHR	reductase
AA314_00259	ENOG4105CC0	LysR family Transcriptional regulator
AA314_00260	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
AA314_00263	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
AA314_00264	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
AA314_00266	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
AA314_00271	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
AA314_00281	ENOG4105EG6	Saccharopine dehydrogenase
AA314_00284	ENOG4107EPV	Aminotransferase class V
AA314_00285	ENOG4105BZU	Histidine kinase
AA314_00298	ENOG4107SQD	Transcriptional regulator, GntR family
AA314_00299	ENOG4105CM2	brancheD-chain amino acid aminotransferase
AA314_00301	ENOG4105E39	Enoyl-CoA hydratase
AA314_00302	ENOG410834F	Transcriptional regulator
AA314_00303	ENOG4106A3M	Cytochrome p-450
AA314_00313	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
AA314_00315	ENOG4105ECY	inositol monophosphatase
AA314_00320	ENOG41069ER	domain protein
AA314_00325	ENOG4105CS6	Rhs element vgr protein
AA314_00330	ENOG4105C8Q	Methyl-accepting chemotaxis
AA314_00331	ENOG4105CV8	reductase
AA314_00335	ENOG4105F7V	ErfK ybiS ycfS ynhG family protein
AA314_00342	ENOG4108Q5Y	Membrane
AA314_00349	ENOG4105DKQ	ROK family
AA314_00352	ENOG4105E0R	Deoxyhypusine synthase
AA314_00359	ENOG4105ED2	Beta-lactamase
AA314_00369	ENOG4105IGJ	Zn-dependent Hydrolase of the beta-lactamase fold protein
AA314_00386	ENOG4105BZ9	Cytochrome C oxidase, subunit I
AA314_00393	ENOG4107SFQ	iron-sulfur binding
AA314_00401	ENOG41080XQ	Signal transduction protein with cbs domains
AA314_00404	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
AA314_00409	ENOG41067HS	methyltransferase
AA314_00410	ENOG4108QBF	Transcriptional regulator
AA314_00414	ENOG4107PU6	Membrane
AA314_00417	ENOG4105FA0	parb-like partition protein
AA314_00418	ENOG4107QJE	Chromosome Partitioning Protein
AA314_00420	ENOG4105BZU	Histidine kinase
AA314_00421	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
AA314_00422	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
AA314_00423	ENOG4105BZU	Histidine kinase
AA314_00424	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
AA314_00425	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
AA314_00430	ENOG41082BE	ankyrin repeat-containing protein
AA314_00448	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
AA314_00453	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
AA314_00454	ENOG41084M4	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
AA314_00455	ENOG4108CXZ	50S ribosomal protein l34
AA314_00456	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
AA314_00462	ENOG4105E4G	Type IV pilus
AA314_00467	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
AA314_00472	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
AA314_00473	ENOG4105BZU	Histidine kinase
AA314_00486	ENOG4105KVH	Transcriptional regulator
AA314_00487	ENOG4105ECR	NmrA family
AA314_00490	ENOG4107Y80	Major Facilitator superfamily
AA314_00492	ENOG4105PNM	synthesis protein
AA314_00504	ENOG4105CNA	YD repeat protein
AA314_00506	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
AA314_00507	ENOG4106NZI	LysR family Transcriptional regulator
AA314_00508	ENOG4105T0Z	Conserved Protein
AA314_00513	ENOG4105BZU	Histidine kinase
AA314_00514	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
AA314_00518	ENOG4108W6G	cytochrome C
AA314_00519	ENOG4105EAU	Plays a role in nitrite reduction (By similarity)
AA314_00523	ENOG4105D7Z	glutathione synthase
AA314_00528	ENOG4108SPH	protein kinase (EC 2.7.11.1)
AA314_00535	ENOG4107SET	aldo keto reductase
AA314_00536	ENOG4105E0X	reductase
AA314_00538	ENOG4105EYW	Ion transport protein
AA314_00540	ENOG4108SPH	protein kinase (EC 2.7.11.1)
AA314_00549	ENOG4105BZU	Histidine kinase
AA314_00563	ENOG4105BZP	glycoside hydrolase 15-related
AA314_00565	ENOG4105E18	UPF0276 protein
AA314_00567	ENOG4108HMN	Caspase domain
AA314_00569	ENOG4105DFS	Conserved Protein
AA314_00573	ENOG4105F8J	Adenylate Guanylate cyclase
AA314_00578	ENOG4108V5V	Serine Threonine protein kinase
AA314_00584	ENOG41080C8	DUF218 domain
AA314_00596	ENOG4108Z4T	Peptidase M50
AA314_00598	ENOG4107VAM	peptidase, m28
AA314_00612	ENOG4108NIW	Leucine export protein LeuE
AA314_00616	ENOG4105E0Y	RtcB Protein
AA314_00618	ENOG4107EMZ	glycosyl transferase family
AA314_00620	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AA314_00628	ENOG4105DJQ	tetratricopeptide tpr_2 repeat protein
AA314_00636	ENOG4105D05	Receptor
AA314_00638	ENOG4105E6M	Sulphatase-modifying factor protein
AA314_00647	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
AA314_00650	ENOG4108K2F	hydrolase Family 5
AA314_00654	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
AA314_00656	ENOG4105EXC	Acyl-transferase
AA314_00663	ENOG4105D9P	serine threonine protein kinase
AA314_00666	ENOG4106R7G	Glycoside hydrolase family 5
AA314_00667	ENOG4105D7W	serine acetyltransferase
AA314_00671	ENOG4105CJW	magnesium transporter
AA314_00674	ENOG4105D3Q	Sugar transferase
AA314_00676	ENOG4107UVD	Beta-phosphoglucomutase family hydrolase
AA314_00680	ENOG4106A3M	Cytochrome p-450
AA314_00682	ENOG4105BZP	glycoside hydrolase 15-related
AA314_00685	ENOG4107QR7	peptidase S8 and S53, subtilisin, kexin, sedolisin
AA314_00687	ENOG4105CEY	Amp-dependent synthetase and ligase
AA314_00693	ENOG4105C6T	cysteine synthase
AA314_00700	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
AA314_00701	ENOG4105BZU	Histidine kinase
AA314_00704	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
AA314_00708	ENOG4105BZU	Histidine kinase
AA314_00709	ENOG4105BZU	Histidine kinase
AA314_00711	ENOG4107R1I	NAD-dependent malic enzyme
AA314_00712	ENOG4108JPV	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
AA314_00715	ENOG4108V1T	peptidylprolyl cis-trans isomerase
AA314_00717	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
AA314_00722	ENOG4105YGK	Pfam:UPF0157
AA314_00723	ENOG4105KHA	Glyoxalase Bleomycin resistance protein (Dioxygenase
AA314_00726	ENOG4105BZU	Histidine kinase
AA314_00733	ENOG4105DGI	Alkaline phosphatase
AA314_00735	ENOG4107SM8	Adenylate Guanylate cyclase
AA314_00736	ENOG4107VWA	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation (By similarity)
AA314_00737	ENOG4107RRE	RNA-directed DNA polymerase
AA314_00759	ENOG4105BZU	Histidine kinase
AA314_00762	ENOG4105ES5	Histidine kinase
AA314_00768	ENOG4108J2P	Alpha beta hydrolase fold
AA314_00769	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
AA314_00775	ENOG4105EMU	Dehydrogenase
AA314_00783	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
AA314_00791	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
AA314_00795	ENOG4105BZU	Histidine kinase
AA314_00804	ENOG4105BZU	Histidine kinase
AA314_00805	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AA314_00814	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
AA314_00817	ENOG4108NVR	Methyl-accepting chemotaxis
AA314_00820	ENOG4108VCT	Sulfite exporter TauE/SafE
AA314_00821	ENOG41082J7	Rhodanese domain protein
AA314_00824	ENOG4107S7U	Sulfide dehydrogenase
AA314_00827	ENOG4105CHF	Glutathione S-transferase
AA314_00836	ENOG4107EFQ	arachidonate 15-lipoxygenase
AA314_00847	ENOG4105BZU	Histidine kinase
AA314_00848	ENOG4105BZU	Histidine kinase
AA314_00850	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
AA314_00851	ENOG4105DJB	Major Facilitator Superfamily
AA314_00852	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
AA314_00855	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
AA314_00856	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
AA314_00859	ENOG4105CHR	reductase
AA314_00861	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
AA314_00862	ENOG4105CEY	Amp-dependent synthetase and ligase
AA314_00865	ENOG4108MUZ	hydrolase
AA314_00876	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
AA314_00878	ENOG4105CPN	adenine deaminase
AA314_00881	ENOG4105GB5	regulatory protein RecX
AA314_00882	ENOG4105CSU	acyl-Coa dehydrogenase
AA314_00890	ENOG4105C8Q	Methyl-accepting chemotaxis
AA314_00892	ENOG4105BZU	Histidine kinase
AA314_00893	ENOG4105BZU	Histidine kinase
AA314_00899	ENOG4105E18	UPF0276 protein
AA314_00905	ENOG4105BZU	Histidine kinase
AA314_00909	ENOG4105E0X	reductase
AA314_00910	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
AA314_00912	ENOG4108TQ9	Histidine kinase
AA314_00914	ENOG4105D9P	serine threonine protein kinase
AA314_00915	ENOG4108UXN	response regulator
AA314_00917	ENOG4108IG5	Transcriptional regulator
AA314_00918	ENOG4105C6T	cysteine synthase
AA314_00919	ENOG4105EUP	HipA domain protein
AA314_00921	ENOG4105MIR	Phenylalanine 4-monooxygenase
AA314_00925	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
AA314_00929	ENOG4105DUM	transcriptional regulator, lysR family
AA314_00935	ENOG4105DHJ	ABC, transporter
AA314_00939	ENOG4105CF7	AraC family transcriptional regulator
AA314_00940	ENOG4105EMU	Dehydrogenase
AA314_00945	ENOG4105CHR	reductase
AA314_00952	ENOG4105BZP	glycoside hydrolase 15-related
AA314_00953	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
AA314_00958	ENOG4105C5R	Aminotransferase
AA314_00968	ENOG4105BZU	Histidine kinase
AA314_00975	ENOG4108SPH	protein kinase (EC 2.7.11.1)
AA314_00977	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
AA314_00983	ENOG4105BZU	Histidine kinase
AA314_00986	ENOG4108ZZF	transport protein (ExbD)
AA314_00987	ENOG4105SG9	biopolymer transport protein, ExbD
AA314_00990	ENOG4108PBA	serine threonine protein kinase
AA314_00991	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
AA314_00995	ENOG4105DF6	Fe-S oxidoreductase
AA314_01004	ENOG4108IFH	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AA314_01012	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AA314_01013	ENOG4107TPY	serine threonine protein kinase
AA314_01017	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
AA314_01022	ENOG4108TQ9	Histidine kinase
AA314_01025	ENOG4105C26	Dehydrogenase
AA314_01033	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
AA314_01038	ENOG4108KPZ	tonB-dependent Receptor
AA314_01039	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
AA314_01040	ENOG4105CFG	Acts as a chaperone (By similarity)
AA314_01041	ENOG4108SPH	protein kinase (EC 2.7.11.1)
AA314_01046	ENOG4105C0H	protease
AA314_01047	ENOG4105C0H	protease
AA314_01048	ENOG4105WH1	Two component transcriptional regulator luxr family
AA314_01057	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
AA314_01065	ENOG4105CPT	Alpha beta hydrolase
AA314_01068	ENOG4106A3M	Cytochrome p-450
AA314_01075	ENOG41080HT	Transcriptional regulator, arsr family
AA314_01079	ENOG4105VUN	Transcriptional regulator
AA314_01081	ENOG4106I9T	
AA314_01111	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
AA314_01112	ENOG4105GR3	Histidine kinase
AA314_01113	ENOG4105D9U	N-acetyltransferase
AA314_01119	ENOG4108UPT	UPF0178 protein
AA314_01125	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
AA314_01126	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
AA314_01127	ENOG4107QY0	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
AA314_01128	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
AA314_01129	ENOG4106YVY	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) (By similarity)
AA314_01130	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AA314_01131	ENOG4105CHR	reductase
AA314_01133	ENOG410642W	LysR family Transcriptional regulator
AA314_01143	ENOG4107EFQ	arachidonate 15-lipoxygenase
AA314_01145	ENOG4105WG9	Conserved Protein
AA314_01146	ENOG4105BZU	Histidine kinase
AA314_01147	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
AA314_01159	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
AA314_01160	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AA314_01165	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
AA314_01168	ENOG4105CVN	desaturase
AA314_01169	ENOG4105EMU	Dehydrogenase
AA314_01176	ENOG4107TEJ	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
AA314_01177	ENOG4107TEJ	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
AA314_01178	ENOG4107XN1	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
AA314_01181	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
AA314_01187	ENOG41082F9	transcriptional regulator
AA314_01193	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
AA314_01194	ENOG4108SPH	protein kinase (EC 2.7.11.1)
AA314_01195	ENOG4107MMM	Anti-sigma-factor antagonist
AA314_01196	ENOG4105FUA	antagonist
AA314_01197	ENOG4105QD0	anti-sigma regulatory factor serine threonine protein kinase
AA314_01199	ENOG4105BZU	Histidine kinase
AA314_01201	ENOG4105F0V	Cell wall hydrolase
AA314_01202	ENOG4107S5I	aldo keto reductase
AA314_01206	ENOG4107GFK	fumarate
AA314_01210	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
AA314_01211	ENOG4105DZW	Dipeptidase
AA314_01217	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
AA314_01218	ENOG4107SKW	Inherit from COG: Alpha beta hydrolase
AA314_01224	ENOG4105D9P	serine threonine protein kinase
AA314_01226	ENOG41061H0	Monooxygenase
AA314_01227	ENOG4105W5Z	
AA314_01233	ENOG4105CX6	glutaminyL-tRNA synthetase
AA314_01234	ENOG4105CX6	glutaminyL-tRNA synthetase
AA314_01237	ENOG4107RN6	Monooxygenase
AA314_01245	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
AA314_01247	ENOG4106PBJ	Serine threonine-protein kinase Pkn6
AA314_01250	ENOG4108AEY	RNA polymerase sigma factor
AA314_01256	ENOG4105BZU	Histidine kinase
AA314_01258	ENOG4108V1U	phospholipid-binding protein
AA314_01259	ENOG4105DTA	methyltransferase
AA314_01266	ENOG4107WJT	it plays a direct role in the translocation of protons across the membrane (By similarity)
AA314_01268	ENOG4108KJP	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
AA314_01269	ENOG4105C3G	gtp-binding protein
AA314_01271	ENOG4105BZN	citrate synthase
AA314_01272	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
AA314_01278	ENOG4107RN3	metallophosphoesterase
AA314_01284	ENOG4105CPC	Aldo Keto reductase
AA314_01285	ENOG4105KF3	Short-chain dehydrogenase reductase Sdr
AA314_01290	ENOG4107SM8	Adenylate Guanylate cyclase
AA314_01292	ENOG4105BZU	Histidine kinase
AA314_01295	ENOG4107YHX	fad dependent oxidoreductase
AA314_01296	ENOG4105W5Z	
AA314_01297	ENOG4105C26	Dehydrogenase
AA314_01300	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
AA314_01303	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
AA314_01322	ENOG4105BZU	Histidine kinase
AA314_01323	ENOG4105BZU	Histidine kinase
AA314_01329	ENOG4105BZU	Histidine kinase
AA314_01334	ENOG4105C3W	Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate (By similarity)
AA314_01336	ENOG4105CKY	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity)
AA314_01337	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
AA314_01344	ENOG4105F6J	Alpha beta hydrolase fold
AA314_01347	ENOG4107QP8	phosphohexose isomerase
AA314_01350	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AA314_01351	ENOG4108VYJ	response regulator receiver protein
AA314_01353	ENOG4108HMN	Caspase domain
AA314_01371	ENOG4108V06	Glutathione peroxidase
AA314_01374	ENOG4105EXU	Membrane
AA314_01375	ENOG4105PNM	synthesis protein
AA314_01382	ENOG4105C9B	Cysteine desulfurase
AA314_01386	ENOG4105BZP	glycoside hydrolase 15-related
AA314_01388	ENOG4105CDA	abc transporter atp-binding protein
AA314_01389	ENOG4105E5Q	amino acid AbC transporter
AA314_01413	ENOG4105BZU	Histidine kinase
AA314_01414	ENOG4105ETX	regulatoR
AA314_01418	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
AA314_01419	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
AA314_01420	ENOG41085KW	ppic-type peptidyL-prolyl cis-trans isomerase
AA314_01425	ENOG4105VC4	domain protein
AA314_01430	ENOG4107VRB	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
AA314_01431	ENOG4105E09	nadh pyrophosphatase
AA314_01433	ENOG4105BZ1	(ABC) transporter
AA314_01434	ENOG4105BZ1	(ABC) transporter
AA314_01438	ENOG4108SPH	protein kinase (EC 2.7.11.1)
AA314_01439	ENOG4105D05	Receptor
AA314_01443	ENOG4105ETX	regulatoR
AA314_01444	ENOG4105D9P	serine threonine protein kinase
AA314_01447	ENOG4105ER2	Ompa motb domain protein
AA314_01455	ENOG4105CEY	Amp-dependent synthetase and ligase
AA314_01456	ENOG41084M5	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
AA314_01459	ENOG410624X	efflux transporter, rnd family, mfp subunit
AA314_01461	ENOG4105BZU	Histidine kinase
AA314_01466	ENOG4105BZU	Histidine kinase
AA314_01471	ENOG4105CHM	Aminotransferase
AA314_01477	ENOG4105C9U	ATP-dependent DNA helicase RecQ
AA314_01479	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
AA314_01484	ENOG4105E4C	Lytic transglycosylase catalytic
AA314_01487	ENOG4105CHM	Aminotransferase
AA314_01489	ENOG4108P4H	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
AA314_01490	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
AA314_01493	ENOG4105CQZ	Histidine kinase
AA314_01494	ENOG4105C7N	Xanthine uracil vitamin C permease
AA314_01495	ENOG4105VEQ	Cold shock protein
AA314_01508	ENOG4105E66	phosphoriboisomerase A
AA314_01510	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AA314_01511	ENOG4105FQP	Beta-lactamase
AA314_01512	ENOG4108SPH	protein kinase (EC 2.7.11.1)
AA314_01513	ENOG4105E3A	(ABC) transporter
AA314_01514	ENOG4105DA5	(ABC) transporter
AA314_01515	ENOG4105C5H	ABC transporter
AA314_01522	ENOG4107Y9E	nuclease
AA314_01527	ENOG4105NPE	arsR family transcriptional regulator
AA314_01530	ENOG4105UYK	outer membrane protein a
AA314_01534	ENOG4108IJ8	ABC transporter
AA314_01535	ENOG4105E90	ABC transporter
AA314_01538	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
AA314_01542	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
AA314_01543	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
AA314_01544	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
AA314_01550	ENOG4105C26	Dehydrogenase
AA314_01554	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
AA314_01557	ENOG410841Q	phosphoesterase PA-phosphatase related protein
AA314_01562	ENOG4108IJF	Heavy metal efflux pump, CzcA
AA314_01566	ENOG4105BZU	Histidine kinase
AA314_01567	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AA314_01569	ENOG4105EQK	-acetyltransferase
AA314_01570	ENOG4105BZU	Histidine kinase
AA314_01571	ENOG4107R72	Ceramidase
AA314_01573	ENOG4107QPV	Serine Threonine protein kinase
AA314_01574	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
AA314_01578	ENOG41067SE	Tetr family transcriptional regulator
AA314_01592	ENOG4108Q9H	CobQ/CobB/MinD/ParA nucleotide binding domain
AA314_01598	ENOG4105CJ1	ABC, transporter
AA314_01607	ENOG4105BZU	Histidine kinase
AA314_01608	ENOG4105KCK	Peptidoglycan-associated lipoprotein
AA314_01610	ENOG4105BZU	Histidine kinase
AA314_01614	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
AA314_01617	ENOG4108ZHJ	Organic hydroperoxide resistance protein
AA314_01619	ENOG4105FQP	Beta-lactamase
AA314_01623	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AA314_01625	ENOG4108SPH	protein kinase (EC 2.7.11.1)
AA314_01627	ENOG4105EFZ	amidohydrolase
AA314_01633	ENOG4105D74	hydrolase
AA314_01636	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
AA314_01638	ENOG4108IG5	Transcriptional regulator
AA314_01639	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
AA314_01646	ENOG4105VEQ	Cold shock protein
AA314_01649	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
AA314_01651	ENOG4105CRW	Short chain fatty acid transporter
AA314_01653	ENOG4107QPV	Serine Threonine protein kinase
AA314_01656	ENOG4105EFQ	Two component transcriptional regulator (Winged helix family
AA314_01657	ENOG4105BZU	Histidine kinase
AA314_01659	ENOG4108Q9V	regulatoR
AA314_01661	ENOG4105BZU	Histidine kinase
AA314_01665	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
AA314_01668	ENOG41065SU	Two-component system sensor kinase
AA314_01672	ENOG4105BZ1	(ABC) transporter
AA314_01674	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
AA314_01675	ENOG4105IBP	Cyclic peptide transporter
AA314_01677	ENOG4108SPH	protein kinase (EC 2.7.11.1)
AA314_01688	ENOG4107QPV	Serine Threonine protein kinase
AA314_01696	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
AA314_01699	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
AA314_01704	ENOG4105W5Z	
AA314_01705	ENOG4107YHX	fad dependent oxidoreductase
AA314_01709	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AA314_01714	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
AA314_01715	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
AA314_01726	ENOG41088YS	Glycosyl transferase (Group 1
AA314_01728	ENOG4105EFZ	amidohydrolase
AA314_01729	ENOG41063Z6	transcriptional regulator, lysR family
AA314_01730	ENOG4105C4R	Atp-dependent dna helicase
AA314_01736	ENOG4105E2Q	3-(3-hydroxy-phenyl)propionate hydroxylase
AA314_01739	ENOG4107QS8	(LipO)protein
AA314_01744	ENOG4105CSU	acyl-Coa dehydrogenase
AA314_01748	ENOG4105CHB	tonB-dependent Receptor
AA314_01750	ENOG4105BZU	Histidine kinase
AA314_01752	ENOG4105GR3	Histidine kinase
AA314_01762	ENOG4105DYB	Isoaspartyl dipeptidase
AA314_01767	ENOG4107JEE	Short-chain dehydrogenase reductase Sdr
AA314_01771	ENOG4108KZ5	Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway (By similarity)
AA314_01782	ENOG4107AF9	
AA314_01783	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
AA314_01785	ENOG4105CFP	Peptidase U32
AA314_01788	ENOG410624X	efflux transporter, rnd family, mfp subunit
AA314_01792	ENOG4106A3M	Cytochrome p-450
AA314_01793	ENOG4105EV4	Multidrug resistance protein mdtH
AA314_01797	ENOG4107UQD	Hydrolyzes N-terminal residues in D-amino acid- containing peptides (By similarity)
AA314_01798	ENOG41067B5	Histone deacetylase superfamily protein
AA314_01809	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
AA314_01827	ENOG4105EYW	Ion transport protein
AA314_01830	ENOG4107VAM	peptidase, m28
AA314_01831	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
AA314_01834	ENOG4105R8A	Heat shock protein
AA314_01837	ENOG4105F0N	pyrophosphate phospho-hydrolase
AA314_01839	ENOG4105CYM	Glutathione S-transferase
AA314_01841	ENOG4105DPV	During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co- crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2 ) ion and storing it in the form of Fe(3 ) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2 ) ions, which prevents hydroxyl radical production by the Fenton reaction
AA314_01850	ENOG4105C8Q	Methyl-accepting chemotaxis
AA314_01857	ENOG4107QPV	Serine Threonine protein kinase
AA314_01860	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
AA314_01861	ENOG4108RZE	Tetr family transcriptional regulator
AA314_01862	ENOG4107RN3	metallophosphoesterase
AA314_01866	ENOG4105EWK	phytoene
AA314_01867	ENOG4105FE1	phytoene synthase
AA314_01869	ENOG4107VFM	Dehydrogenase
AA314_01875	ENOG4108XDN	Transcriptional regulator
AA314_01876	ENOG4107X2D	transcriptional regulator, merr family
AA314_01880	ENOG4105DUX	Transporter
AA314_01881	ENOG4106WR0	acetolactate synthase (large subunit)
AA314_01885	ENOG4105D4P	Coproporphyrinogen iii oxidase
AA314_01889	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
AA314_01892	ENOG4105F99	Hydroxymethylglutaryl-CoA synthase
AA314_01893	ENOG4108NA0	Uncharacterized conserved protein (COG2071)
AA314_01895	ENOG4107TPY	serine threonine protein kinase
AA314_01899	ENOG4107QPV	Serine Threonine protein kinase
AA314_01905	ENOG4107QPD	alcohol dehydrogenase
AA314_01908	ENOG4105EJC	lysr family transcriptional regulator
AA314_01912	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
AA314_01915	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AA314_01917	ENOG4105EVH	UPF0753 protein
AA314_01918	ENOG4105CHH	sulfate transporter
AA314_01919	ENOG4105EMN	RNA polymerase sigma factor
AA314_01922	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AA314_01928	ENOG4105C9B	Cysteine desulfurase
AA314_01930	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
AA314_01931	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
AA314_01934	ENOG4108UGD	Serine Threonine protein kinase
AA314_01938	ENOG4105CNF	WD-40 repeat protein
AA314_01941	ENOG4108SDH	ABC, transporter
AA314_01942	ENOG4108IUW	ABC transporter
AA314_01951	ENOG4107R72	Ceramidase
AA314_01954	ENOG4105CPF	Cell wall formation (By similarity)
AA314_01964	ENOG4105CAN	Short-chain dehydrogenase reductase Sdr
AA314_01965	ENOG4105JAB	phenazine biosynthesis protein, phzf family
AA314_01966	ENOG4107RH8	nuclease SbcCD subunit D
AA314_01967	ENOG4105EYH	Exonuclease
AA314_01973	ENOG4105F8J	Adenylate Guanylate cyclase
AA314_01984	ENOG4108RYR	transcriptional regulator AsnC family
AA314_01989	ENOG4105EJ2	Transcriptional regulator
AA314_01990	ENOG4108YIQ	Alpha beta hydrolase
AA314_02006	ENOG4105CV6	ABC transporter, permease
AA314_02007	ENOG4108I0Y	(ABC) transporter
AA314_02008	ENOG4108UJV	acyl-CoA thioesterase i
AA314_02010	ENOG4107R5W	Monooxygenase
AA314_02021	ENOG41083AI	transcriptional regulator), MarR family
AA314_02024	ENOG4105EQ0	Major Facilitator superfamily
AA314_02025	ENOG4105CR8	Transcriptional regulator
AA314_02028	ENOG4105CBS	Chea signal transduction histidine kinase
AA314_02030	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
AA314_02031	ENOG4105DX1	Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity)
AA314_02038	ENOG4105CA0	peroxidase
AA314_02055	ENOG4107QRT	dEAD DEAH box helicase
AA314_02059	ENOG4105EB1	binding-protein-dependent transport systems inner membrane Component
AA314_02061	ENOG4108IJ9	(ABC) transporter
AA314_02062	ENOG4108IJ9	(ABC) transporter
AA314_02064	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
AA314_02066	ENOG4105BZU	Histidine kinase
AA314_02068	ENOG4105BZU	Histidine kinase
AA314_02074	ENOG4106PBJ	Serine threonine-protein kinase Pkn6
AA314_02078	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
AA314_02086	ENOG4108SJC	Membrane
AA314_02093	ENOG41080XQ	Signal transduction protein with cbs domains
AA314_02097	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
AA314_02099	ENOG4105BZU	Histidine kinase
AA314_02101	ENOG4108SEK	ompa motb domain protein
AA314_02104	ENOG4107WZZ	SMC domain protein
AA314_02107	ENOG4108JA2	transcriptioN-repair coupling factor
AA314_02112	ENOG4108YZA	Nitrogen regulatory protein pii
AA314_02114	ENOG4108QV3	biosynthesis protein
AA314_02123	ENOG4105E2K	Glycosyl transferase (Group 1
AA314_02128	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
AA314_02131	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
AA314_02132	ENOG4105ESV	Glycosyl transferase, family 4
AA314_02137	ENOG4105DHF	Membrane
AA314_02139	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
AA314_02141	ENOG4108HMN	Caspase domain
AA314_02144	ENOG4105EV9	Alpha Beta Hydrolase
AA314_02145	ENOG4107JEE	Short-chain dehydrogenase reductase Sdr
AA314_02150	ENOG4105EY2	Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2) (By similarity)
AA314_02151	ENOG4105D1S	lipid A biosynthesis
AA314_02154	ENOG4108IUZ	ABC transporter
AA314_02155	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AA314_02157	ENOG4105E2K	Glycosyl transferase (Group 1
AA314_02158	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
AA314_02160	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
AA314_02185	ENOG41068JE	domain protein
AA314_02188	ENOG4108TGY	Glutathione S-transferase
AA314_02193	ENOG4108SPH	protein kinase (EC 2.7.11.1)
AA314_02220	ENOG4105D9P	serine threonine protein kinase
AA314_02221	ENOG4105D9P	serine threonine protein kinase
AA314_02234	ENOG4105BZU	Histidine kinase
AA314_02236	ENOG4105BZU	Histidine kinase
AA314_02238	ENOG4105BZU	Histidine kinase
AA314_02239	ENOG4105ES5	Histidine kinase
AA314_02241	ENOG4105D17	glycoside hydrolase, family 3 domain protein
AA314_02243	ENOG4105DM4	PTS System
AA314_02244	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
AA314_02246	ENOG4107QPV	Serine Threonine protein kinase
AA314_02256	ENOG4108UUM	single-stranded DNA-binding protein
AA314_02257	ENOG4108NU2	Succinate dehydrogenase cytochrome b558 subunit
AA314_02258	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
AA314_02260	ENOG4105EM7	Selenocysteine-specific translation elongation factor
AA314_02261	ENOG4105BZU	Histidine kinase
AA314_02262	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AA314_02263	ENOG41080E2	ribosomal-protein-alanine acetyltransferase
AA314_02264	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AA314_02265	ENOG4105C8S	subunit m
AA314_02266	ENOG4105D65	subunit l
AA314_02267	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AA314_02268	ENOG4107YX3	NADH dehydrogenase subunit j
AA314_02271	ENOG4108VYJ	response regulator receiver protein
AA314_02272	ENOG4105D9P	serine threonine protein kinase
AA314_02273	ENOG4105EAC	phosphoserine phosphatase
AA314_02277	ENOG4105VN1	Heat shock protein
AA314_02278	ENOG4105ETX	regulatoR
AA314_02279	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
AA314_02280	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
AA314_02281	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
AA314_02283	ENOG4105BZ1	(ABC) transporter
AA314_02284	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
AA314_02285	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
AA314_02286	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AA314_02287	ENOG4105D9P	serine threonine protein kinase
AA314_02291	ENOG4105C34	Pseudouridine synthase
AA314_02292	ENOG4105BZU	Histidine kinase
AA314_02293	ENOG4108V5V	Serine Threonine protein kinase
AA314_02303	ENOG4105D0M	Protease HtpX homolog
AA314_02305	ENOG4105IK6	Terpene synthase metal-binding domain-containing protein
AA314_02306	ENOG4105ESN	nucleotide-binding protein
AA314_02307	ENOG4105ESN	nucleotide-binding protein
AA314_02312	ENOG4105HBR	Rna-binding protein
AA314_02313	ENOG4105DVC	DnaJ domain protein
AA314_02322	ENOG4105DJT	lAO AO transport system ATPase
AA314_02323	ENOG4107QSA	Oxaloacetate decarboxylase
AA314_02324	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
AA314_02326	ENOG4107QX3	carboxylase
AA314_02329	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
AA314_02330	ENOG4105DGW	oligopeptidase A
AA314_02336	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
AA314_02337	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
AA314_02341	ENOG4108UGD	Serine Threonine protein kinase
AA314_02346	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
AA314_02348	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AA314_02352	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AA314_02355	ENOG4105BZU	Histidine kinase
AA314_02358	ENOG41085PJ	rdd domain containing protein
AA314_02360	ENOG4107TVK	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
AA314_02364	ENOG4105F8J	Adenylate Guanylate cyclase
AA314_02366	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
AA314_02372	ENOG4105EKQ	RNA-directed DNA polymerase
AA314_02373	ENOG4105C1V	Peptidase, M16
AA314_02376	ENOG4105CSA	Coproporphyrinogen iii oxidase
AA314_02380	ENOG4105CDV	Ompa motb domain protein
AA314_02385	ENOG4105JZI	cytochrome P450
AA314_02391	ENOG4107FW0	short-chain dehydrogenase reductase
AA314_02392	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
AA314_02395	ENOG4105JRK	feS assembly protein SufD
AA314_02396	ENOG4105C9B	Cysteine desulfurase
AA314_02397	ENOG4108UNV	SUF system FeS assembly protein, NifU family
AA314_02398	ENOG4105VG1	fes assembly suf system protein
AA314_02401	ENOG4105E39	Enoyl-CoA hydratase
AA314_02403	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
AA314_02406	ENOG4105D9P	serine threonine protein kinase
AA314_02407	ENOG4105C9U	ATP-dependent DNA helicase RecQ
AA314_02410	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
AA314_02411	ENOG4108R86	Transcriptional regulator
AA314_02412	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AA314_02413	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AA314_02416	ENOG4108EE5	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AA314_02420	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AA314_02421	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AA314_02430	ENOG4108JPV	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
AA314_02431	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
AA314_02448	ENOG4107Z7P	Ferredoxin
AA314_02450	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
AA314_02454	ENOG4106A3M	Cytochrome p-450
AA314_02460	ENOG4108NNI	Beta-lactamase domain-containing protein
AA314_02464	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
AA314_02466	ENOG4107RCI	amp-dependent synthetase and ligase
AA314_02467	ENOG4106A3M	Cytochrome p-450
AA314_02477	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AA314_02487	ENOG4105BZU	Histidine kinase
AA314_02492	ENOG4107UUY	ec 2.7.1.11
AA314_02494	ENOG4105CYM	Glutathione S-transferase
AA314_02495	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
AA314_02498	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
AA314_02505	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AA314_02509	ENOG4107SET	aldo keto reductase
AA314_02512	ENOG4105M3Z	response regulator
AA314_02513	ENOG4105BZU	Histidine kinase
AA314_02514	ENOG4105BZU	Histidine kinase
AA314_02517	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
AA314_02519	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
AA314_02520	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
AA314_02521	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
AA314_02523	ENOG4105CHM	Aminotransferase
AA314_02526	ENOG4105EPD	Oligopeptide transporter, Opt family
AA314_02528	ENOG4105C8Q	Methyl-accepting chemotaxis
AA314_02530	ENOG4107SQU	synthase
AA314_02533	ENOG4108VAU	general secretion pathway protein G
AA314_02537	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
AA314_02543	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
AA314_02545	ENOG4105CUX	Signal transduction histidine kinase
AA314_02546	ENOG4105BZU	Histidine kinase
AA314_02549	ENOG4105BZU	Histidine kinase
AA314_02551	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
AA314_02558	ENOG4105DY9	regulatoR
AA314_02566	ENOG4107QRT	dEAD DEAH box helicase
AA314_02568	ENOG4107T0X	DNA ligase
AA314_02575	ENOG4105DFK	Polyphosphate glucokinase
AA314_02580	ENOG4105D7Q	type ii secretion system
AA314_02583	ENOG4108HRK	Histidine kinase
AA314_02585	ENOG4105C1Q	protoporphyrinogen oxidase
AA314_02586	ENOG4108RU0	short-chain dehydrogenase reductase
AA314_02587	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
AA314_02588	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
AA314_02589	ENOG4105D9P	serine threonine protein kinase
AA314_02591	ENOG4105C37	(CBS) domain
AA314_02594	ENOG4108PBA	serine threonine protein kinase
AA314_02596	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
AA314_02603	ENOG4105BZU	Histidine kinase
AA314_02604	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
AA314_02614	ENOG4105BZU	Histidine kinase
AA314_02616	ENOG4106A3M	Cytochrome p-450
AA314_02617	ENOG4105DSQ	Nitric oxide reductase
AA314_02621	ENOG4105DNE	Transposase
AA314_02632	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
AA314_02633	ENOG4105D9P	serine threonine protein kinase
AA314_02634	ENOG4108PNU	Involved in the degradation of specific anti-sigma factors (By similarity)
AA314_02637	ENOG4107XM9	(LipO)protein
AA314_02642	ENOG4105CI2	imidazolone-5-propionate hydrolase
AA314_02650	ENOG4105ETX	regulatoR
AA314_02651	ENOG4105BZU	Histidine kinase
AA314_02653	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
AA314_02656	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
AA314_02660	ENOG4105Q36	FHA domain containing protein
AA314_02661	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
AA314_02662	ENOG4107SDU	Methyl-accepting chemotaxis
AA314_02664	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
AA314_02665	ENOG4105DQE	DNA ligase
AA314_02667	ENOG4107QM5	aconitate hydratase
AA314_02669	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
AA314_02670	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
AA314_02674	ENOG4105C2I	pirin domain protein
AA314_02676	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
AA314_02684	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
AA314_02687	ENOG4105CHR	reductase
AA314_02689	ENOG4105EXC	Acyl-transferase
AA314_02694	ENOG4105ENH	Sulfatase
AA314_02696	ENOG4105DGU	Histone deacetylase
AA314_02700	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
AA314_02701	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
AA314_02704	ENOG4105CJ1	ABC, transporter
AA314_02705	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AA314_02711	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
AA314_02713	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
AA314_02714	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
AA314_02715	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
AA314_02716	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
AA314_02717	ENOG4108SPH	protein kinase (EC 2.7.11.1)
AA314_02723	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
AA314_02735	ENOG4108JQ7	(ABC) transporter
AA314_02736	ENOG4105C3U	ABC transporter
AA314_02743	ENOG4105JZI	cytochrome P450
AA314_02745	ENOG4105CHU	acetyl-coa acetyltransferase
AA314_02750	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
AA314_02751	ENOG4105DTQ	mandelate racemase muconate lactonizing
AA314_02756	ENOG4105E2K	Glycosyl transferase (Group 1
AA314_02758	ENOG4105BZG	amino acid carrier protein
AA314_02760	ENOG4108KPZ	tonB-dependent Receptor
AA314_02763	ENOG4105BZM	domain protein
AA314_02764	ENOG4107TSX	ABC branched chain amino acid family transporter periplasmic ligand binding protein
AA314_02765	ENOG4105CQZ	Histidine kinase
AA314_02767	ENOG4105CPC	Aldo Keto reductase
AA314_02770	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
AA314_02771	ENOG4107T8T	UPF0173 metal-dependent hydrolase
AA314_02777	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
AA314_02778	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
AA314_02779	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
AA314_02787	ENOG4105BZU	Histidine kinase
AA314_02794	ENOG4107TPY	serine threonine protein kinase
AA314_02798	ENOG4105EBR	Carboxylesterase
AA314_02808	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AA314_02809	ENOG4108SPH	protein kinase (EC 2.7.11.1)
AA314_02816	ENOG4105CHR	reductase
AA314_02817	ENOG4105C1G	acyl-Coa dehydrogenase
AA314_02819	ENOG4105EHU	Circadian clock protein KaiC
AA314_02820	ENOG4105BZU	Histidine kinase
AA314_02834	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
AA314_02835	ENOG4105C1J	atp-dependent rna helicase
AA314_02838	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
AA314_02839	ENOG41087PP	glycosyltransferase MGT family
AA314_02840	ENOG4107VUB	phosphate binding protein
AA314_02841	ENOG4105C8Q	Methyl-accepting chemotaxis
AA314_02846	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AA314_02864	ENOG4105BZU	Histidine kinase
AA314_02865	ENOG4105BZU	Histidine kinase
AA314_02868	ENOG4105CND	Glycosyl transferase, family 2
AA314_02872	ENOG4105C8T	Leucyl-tRNA synthetase
AA314_02873	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
AA314_02878	ENOG4105C34	Pseudouridine synthase
AA314_02880	ENOG4105C25	Primosomal protein n'
AA314_02881	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
AA314_02883	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
AA314_02885	ENOG4105DR5	peptidase
AA314_02886	ENOG4105K70	DNA-binding protein
AA314_02888	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
AA314_02889	ENOG4107TH8	cina domain protein
AA314_02892	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
AA314_02893	ENOG4105E9Q	Acyl-transferase
AA314_02894	ENOG4105CEP	NADH dehydrogenase
AA314_02901	ENOG4105M8F	Biopolymer transport protein exbD tolR
AA314_02905	ENOG4108KPZ	tonB-dependent Receptor
AA314_02912	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
AA314_02917	ENOG4105VB5	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
AA314_02918	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
AA314_02919	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
AA314_02920	ENOG4105C0D	helicase
AA314_02928	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
AA314_02929	ENOG4105K46	50S ribosomal protein l27
AA314_02930	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AA314_02931	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
AA314_02934	ENOG4105D9P	serine threonine protein kinase
AA314_02936	ENOG4105EQ2	LysR family Transcriptional regulator
AA314_02937	ENOG4105EMU	Dehydrogenase
AA314_02938	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
AA314_02940	ENOG4108VPT	UPF0234 protein
AA314_02945	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
AA314_02952	ENOG4105BZU	Histidine kinase
AA314_02962	ENOG4105F9V	Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid
AA314_02965	ENOG4105CS9	pantothenic acid kinase
AA314_02967	ENOG4105ECP	epimerase
AA314_02970	ENOG4105BZU	Histidine kinase
AA314_02972	ENOG4108HGY	Proline imino-peptidase
AA314_02974	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
AA314_02975	ENOG41086IN	PA14
AA314_02979	ENOG4105CEY	Amp-dependent synthetase and ligase
AA314_02983	ENOG4108K2F	hydrolase Family 5
AA314_03007	ENOG4105BZU	Histidine kinase
AA314_03008	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
AA314_03009	ENOG4105BZU	Histidine kinase
AA314_03014	ENOG4105SG9	biopolymer transport protein, ExbD
AA314_03015	ENOG4108ZZF	transport protein (ExbD)
AA314_03019	ENOG4107S1Q	Phosphatase
AA314_03021	ENOG4105BZU	Histidine kinase
AA314_03023	ENOG4105BZU	Histidine kinase
AA314_03029	ENOG4105K4T	epimerase
AA314_03040	ENOG4108SA1	esterase
AA314_03041	ENOG4105C1Q	protoporphyrinogen oxidase
AA314_03045	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
AA314_03047	ENOG4105BZU	Histidine kinase
AA314_03051	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
AA314_03052	ENOG4105BZU	Histidine kinase
AA314_03053	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
AA314_03054	ENOG4105CEY	Amp-dependent synthetase and ligase
AA314_03056	ENOG4108RXW	HAD-superfamily subfamily IB hydrolase
AA314_03057	ENOG4108KZ5	Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway (By similarity)
AA314_03062	ENOG4105DU1	integral membrane protein, terc
AA314_03063	ENOG4105NWN	ApaG protein
AA314_03064	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
AA314_03068	ENOG4108DT4	serine threonine protein kinase
AA314_03069	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
AA314_03071	ENOG4105CJ1	ABC, transporter
AA314_03075	ENOG4105M3Z	response regulator
AA314_03076	ENOG4105BZU	Histidine kinase
AA314_03082	ENOG4108I5C	dEAD DEAH box helicase
AA314_03083	ENOG4107X2U	Inherit from COG: Exonuclease-like protein
AA314_03086	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
AA314_03092	ENOG4108EF6	Proline imino-peptidase
AA314_03097	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
AA314_03099	ENOG4105DXI	Major Facilitator superfamily
AA314_03105	ENOG4105NQG	DoxX
AA314_03106	ENOG4105C9K	Endothelin-converting enzyme 1
AA314_03109	ENOG4105DPV	During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co- crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2 ) ion and storing it in the form of Fe(3 ) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2 ) ions, which prevents hydroxyl radical production by the Fenton reaction
AA314_03110	ENOG4108X7C	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
AA314_03111	ENOG4105D3R	alkyl hydroperoxide reductase
AA314_03112	ENOG4108JUA	Transcriptional regulator
AA314_03115	ENOG4105E4C	Lytic transglycosylase catalytic
AA314_03121	ENOG4105BZU	Histidine kinase
AA314_03123	ENOG4105CD2	stage iii sporulation protein aa
AA314_03128	ENOG4105CEY	Amp-dependent synthetase and ligase
AA314_03156	ENOG4105NXH	GreA GreB family elongation factor
AA314_03157	ENOG4105MJ9	esterase
AA314_03158	ENOG4105C3J	Cysteine desulfurase
AA314_03161	ENOG4105CIH	Imidazole acetol-phosphate transaminase
AA314_03165	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
AA314_03180	ENOG4107QI1	Mate efflux family protein
AA314_03190	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
AA314_03191	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
AA314_03193	ENOG4105DFU	Cell wall formation (By similarity)
AA314_03194	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AA314_03195	ENOG4105ECY	inositol monophosphatase
AA314_03199	ENOG4105EYW	Ion transport protein
AA314_03208	ENOG4105CXV	gliding motility protein
AA314_03212	ENOG4108SPH	protein kinase (EC 2.7.11.1)
AA314_03213	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
AA314_03214	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
AA314_03216	ENOG4105C6E	dna polymerase iii
AA314_03218	ENOG4108Z6B	deaminase
AA314_03219	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
AA314_03222	ENOG4105CKK	Glycosyl transferase, family 2
AA314_03226	ENOG4105PSQ	Acyl-transferase
AA314_03233	ENOG4105BZU	Histidine kinase
AA314_03234	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
AA314_03239	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
AA314_03243	ENOG4105C9U	ATP-dependent DNA helicase RecQ
AA314_03245	ENOG4105W5Q	DNA repair protein (RadC
AA314_03247	ENOG4105BZU	Histidine kinase
AA314_03248	ENOG4105BZU	Histidine kinase
AA314_03249	ENOG4108KXV	response regulator
AA314_03250	ENOG4105BZU	Histidine kinase
AA314_03252	ENOG4105C3M	thioredoxin reductase
AA314_03253	ENOG4105C28	cystathionine
AA314_03254	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
AA314_03257	ENOG41087PP	glycosyltransferase MGT family
AA314_03261	ENOG4108KF3	Electron transport protein SCO1 SenC
AA314_03266	ENOG41067SE	Tetr family transcriptional regulator
AA314_03269	ENOG4105CPQ	Dehydrogenase
AA314_03270	ENOG4105F99	Hydroxymethylglutaryl-CoA synthase
AA314_03280	ENOG4107ETC	gas vesicle protein
AA314_03282	ENOG4105W2E	Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth (By similarity)
AA314_03283	ENOG4106T9R	serine protease
AA314_03301	ENOG4107QPV	Serine Threonine protein kinase
AA314_03304	ENOG4105K4P	CoA-binding domain protein
AA314_03306	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
AA314_03309	ENOG4108KIH	Inherit from NOG: halimadienyl-diphosphate synthase activity
AA314_03310	ENOG4105JZI	cytochrome P450
AA314_03315	ENOG4108JJA	ABC, transporter
AA314_03321	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
AA314_03322	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
AA314_03327	ENOG4107JEE	Short-chain dehydrogenase reductase Sdr
AA314_03330	ENOG4105CUZ	uba thif-type nad fad binding protein
AA314_03346	ENOG4105C4R	Atp-dependent dna helicase
AA314_03347	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
AA314_03349	ENOG4105CZX	twitching motility protein
AA314_03351	ENOG4105Y3E	Modulates RecA activity (By similarity)
AA314_03352	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AA314_03356	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
AA314_03357	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
AA314_03358	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
AA314_03360	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
AA314_03361	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
AA314_03362	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
AA314_03364	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
AA314_03366	ENOG4108J59	Extracellular solute-binding protein, family 5
AA314_03369	ENOG4108MRH	transcriptional regulatory protein
AA314_03370	ENOG4108UJU	UPF0301 protein
AA314_03376	ENOG4107T6F	Xaa-Pro aminopeptidase
AA314_03377	ENOG4107QPV	Serine Threonine protein kinase
AA314_03388	ENOG4105CA0	peroxidase
AA314_03392	ENOG4105CA0	peroxidase
AA314_03398	ENOG4107SFQ	iron-sulfur binding
AA314_03408	ENOG4105D9P	serine threonine protein kinase
AA314_03415	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
AA314_03424	ENOG4108HMN	Caspase domain
AA314_03425	ENOG4105EP8	Glycosyl Hydrolase Family 88
AA314_03433	ENOG4105D4P	Coproporphyrinogen iii oxidase
AA314_03437	ENOG4105C0D	helicase
AA314_03443	ENOG4105CP2	von willebrand factor, type a
AA314_03445	ENOG4105BZU	Histidine kinase
AA314_03457	ENOG4105D9P	serine threonine protein kinase
AA314_03458	ENOG4105CUB	amino acid
AA314_03465	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AA314_03468	ENOG4105E6M	Sulphatase-modifying factor protein
AA314_03470	ENOG4105BZU	Histidine kinase
AA314_03471	ENOG4105D9P	serine threonine protein kinase
AA314_03475	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
AA314_03477	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
AA314_03485	ENOG4105CC0	LysR family Transcriptional regulator
AA314_03496	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
AA314_03499	ENOG4105CHU	acetyl-coa acetyltransferase
AA314_03500	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AA314_03501	ENOG4105GYP	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity)
AA314_03503	ENOG410901P	UPF0249 protein
AA314_03504	ENOG4105CKK	Glycosyl transferase, family 2
AA314_03506	ENOG4105BZU	Histidine kinase
AA314_03509	ENOG4105D1H	recombination factor protein RarA
AA314_03510	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
AA314_03512	ENOG4105CGH	5'-nucleotidase
AA314_03514	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
AA314_03515	ENOG4105EYM	Major Facilitator superfamily
AA314_03516	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
AA314_03517	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
AA314_03519	ENOG4105C0D	helicase
AA314_03520	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
AA314_03521	ENOG4108ZF3	Phosphatase
AA314_03522	ENOG4105DR5	peptidase
AA314_03524	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
AA314_03525	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
AA314_03526	ENOG4105CE9	30S ribosomal protein S2
AA314_03527	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
AA314_03528	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
AA314_03529	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
AA314_03531	ENOG4105XQ6	frataxin-like protein
AA314_03537	ENOG4105CKK	Glycosyl transferase, family 2
AA314_03554	ENOG4105R8A	Heat shock protein
AA314_03555	ENOG4105CFG	Acts as a chaperone (By similarity)
AA314_03559	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
AA314_03563	ENOG4106F60	Histidine kinase
AA314_03564	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AA314_03567	ENOG4105VEQ	Cold shock protein
AA314_03570	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AA314_03572	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
AA314_03574	ENOG41084JP	30S ribosomal protein S21
AA314_03578	ENOG4105HDK	L-asparaginase
AA314_03579	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
AA314_03581	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
AA314_03593	ENOG4106KE4	Dehydrogenase
AA314_03595	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
AA314_03600	ENOG4105C1J	atp-dependent rna helicase
AA314_03609	ENOG4108JQC	penicillin-binding protein 1A
AA314_03611	ENOG4105CGK	Exodeoxyribonuclease III
AA314_03624	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
AA314_03625	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AA314_03626	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AA314_03630	ENOG4105KCK	Peptidoglycan-associated lipoprotein
AA314_03633	ENOG4108QAF	Methyl-accepting chemotaxis sensory transducer
AA314_03634	ENOG4108QAF	Methyl-accepting chemotaxis sensory transducer
AA314_03635	ENOG4105CBS	Chea signal transduction histidine kinase
AA314_03636	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
AA314_03637	ENOG4105BZU	Histidine kinase
AA314_03641	ENOG41082DI	50s ribosomal protein l31
AA314_03645	ENOG4105E0X	reductase
AA314_03646	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
AA314_03647	ENOG4105E0Y	RtcB Protein
AA314_03648	ENOG4105E9H	Lytic Murein transglycosylase
AA314_03649	ENOG4105CQZ	Histidine kinase
AA314_03652	ENOG4105C8Q	Methyl-accepting chemotaxis
AA314_03653	ENOG4108KIH	Inherit from NOG: halimadienyl-diphosphate synthase activity
AA314_03658	ENOG4105C1J	atp-dependent rna helicase
AA314_03665	ENOG4105C1J	atp-dependent rna helicase
AA314_03675	ENOG4105CHU	acetyl-coa acetyltransferase
AA314_03681	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
AA314_03682	ENOG4105IJJ	transcriptional regulator, crp fnr family
AA314_03683	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AA314_03684	ENOG4105EB3	Histidine kinase
AA314_03696	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
AA314_03698	ENOG4108IXY	short-chain dehydrogenase reductase
AA314_03704	ENOG4107RRE	RNA-directed DNA polymerase
AA314_03706	ENOG4105CI2	imidazolone-5-propionate hydrolase
AA314_03707	ENOG4105DR4	Methyltransferase
AA314_03711	ENOG4108ETT	Dehydrogenase
AA314_03712	ENOG4108SPH	protein kinase (EC 2.7.11.1)
AA314_03713	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
AA314_03721	ENOG4105D9P	serine threonine protein kinase
AA314_03724	ENOG4108HMN	Caspase domain
AA314_03728	ENOG4108JCI	Transcriptional regulator
AA314_03730	ENOG4107SYN	Glycosyl hydrolases family 43
AA314_03731	ENOG4105F8J	Adenylate Guanylate cyclase
AA314_03741	ENOG4105XRQ	Xanthine dehydrogenase accessory factor
AA314_03749	ENOG410870F	Cyclic nucleotide-binding protein
AA314_03750	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
AA314_03753	ENOG4108DT4	serine threonine protein kinase
AA314_03756	ENOG4105D05	Receptor
AA314_03757	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AA314_03763	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
AA314_03764	ENOG4108Z86	Glutamine amidotransferase
AA314_03765	ENOG4105DWF	phosphomethylpyrimidine kinase
AA314_03767	ENOG4105CDU	Replicative dna helicase
AA314_03768	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
AA314_03769	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
AA314_03770	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
AA314_03771	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
AA314_03772	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
AA314_03773	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
AA314_03774	ENOG4105K4W	Could be involved in septation (By similarity)
AA314_03777	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
AA314_03779	ENOG4108JJA	ABC, transporter
AA314_03782	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
AA314_03790	ENOG4105EFI	regulatoR
AA314_03793	ENOG4105BZU	Histidine kinase
AA314_03797	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
AA314_03798	ENOG4107FW0	short-chain dehydrogenase reductase
AA314_03800	ENOG4105VCQ	rubredoxin
AA314_03803	ENOG4105C1V	Peptidase, M16
AA314_03804	ENOG4105BZU	Histidine kinase
AA314_03808	ENOG4105D0M	Protease HtpX homolog
AA314_03817	ENOG4105BZU	Histidine kinase
AA314_03821	ENOG4108ZIT	Ferredoxin, 2FE-2S
AA314_03822	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
AA314_03823	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
AA314_03824	ENOG4108Z4V	iron-sulfur cluster assembly
AA314_03825	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
AA314_03826	ENOG4105C3J	Cysteine desulfurase
AA314_03834	ENOG4108ZMQ	domain protein
AA314_03836	ENOG4105EYM	Major Facilitator superfamily
AA314_03841	ENOG4105D9P	serine threonine protein kinase
AA314_03850	ENOG4105UQX	Mate efflux family protein
AA314_03852	ENOG4105E18	UPF0276 protein
AA314_03858	ENOG4105CS6	Rhs element vgr protein
AA314_03870	ENOG4105CYB	regulatoR
AA314_03871	ENOG4105E0Y	RtcB Protein
AA314_03872	ENOG4105CKX	Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP
AA314_03874	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AA314_03880	ENOG4105CDY	transcriptional regulatory protein
AA314_03881	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
AA314_03882	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
AA314_03895	ENOG4108QCI	YvbH-like oligomerisation region
AA314_03900	ENOG4105CPQ	Dehydrogenase
AA314_03901	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
AA314_03903	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AA314_03904	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
AA314_03909	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
AA314_03914	ENOG4105CFF	transcriptional regulator
AA314_03917	ENOG4105E18	UPF0276 protein
AA314_03924	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
AA314_03926	ENOG4105C9K	Endothelin-converting enzyme 1
AA314_03928	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
AA314_03933	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
AA314_03934	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
AA314_03935	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
AA314_03938	ENOG4105C37	(CBS) domain
AA314_03940	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
AA314_03945	ENOG4108JU7	Transcriptional regulator
AA314_03947	ENOG4105VW4	glutaredoxin 3
AA314_03948	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
AA314_03949	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
AA314_03953	ENOG41084BP	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
AA314_03961	ENOG4105EMN	RNA polymerase sigma factor
AA314_03966	ENOG4106A3M	Cytochrome p-450
AA314_03967	ENOG4105ENE	Histidine kinase
AA314_03968	ENOG4105WH1	Two component transcriptional regulator luxr family
AA314_03970	ENOG4105CHJ	isochorismatase hydrolase
AA314_03973	ENOG4107SFI	Major Facilitator superfamily
AA314_03979	ENOG4105VKD	bioY protein
AA314_03980	ENOG4105CEY	Amp-dependent synthetase and ligase
AA314_03981	ENOG4105BZU	Histidine kinase
AA314_03990	ENOG4105HEI	LysR family (Transcriptional regulator
AA314_03994	ENOG4105CDZ	Carboxymethylenebutenolidase (EC 3.1.1.45)
AA314_03998	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AA314_04003	ENOG4105D9P	serine threonine protein kinase
AA314_04023	ENOG4105CJ1	ABC, transporter
AA314_04024	ENOG4105CFH	Aspartokinase
AA314_04025	ENOG4105F8J	Adenylate Guanylate cyclase
AA314_04046	ENOG4105CGH	5'-nucleotidase
AA314_04049	ENOG4105BZ1	(ABC) transporter
AA314_04052	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
AA314_04065	ENOG4107QPV	Serine Threonine protein kinase
AA314_04067	ENOG4108V5V	Serine Threonine protein kinase
AA314_04073	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AA314_04074	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AA314_04076	ENOG4107VAM	peptidase, m28
AA314_04081	ENOG4105BZU	Histidine kinase
AA314_04082	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
AA314_04085	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
AA314_04086	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
AA314_04087	ENOG4105E2Z	phosphate ABC transporter (Permease
AA314_04088	ENOG4105C8U	phosphate abc transporter
AA314_04089	ENOG4105CVA	phosphate
AA314_04090	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AA314_04093	ENOG4105BZU	Histidine kinase
AA314_04094	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AA314_04097	ENOG4105KNH	Nucleic acid-binding protein
AA314_04100	ENOG4105GR3	Histidine kinase
AA314_04103	ENOG4105CDV	Ompa motb domain protein
AA314_04108	ENOG4105DFH	Transport of potassium into the cell (By similarity)
AA314_04109	ENOG4105CSV	Glutaminase
AA314_04111	ENOG4105CPC	Aldo Keto reductase
AA314_04112	ENOG4108KPJ	rna polymerase sigma factor
AA314_04113	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
AA314_04115	ENOG4105D5T	phosphonate abc transporter
AA314_04121	ENOG4105E4C	Lytic transglycosylase catalytic
AA314_04126	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
AA314_04127	ENOG4105ENX	hydrolase
AA314_04128	ENOG4107RTG	Major Facilitator superfamily
AA314_04129	ENOG410642W	LysR family Transcriptional regulator
AA314_04130	ENOG4105VTR	Integrase
AA314_04137	ENOG4105D64	Mechanosensitive ion channel
AA314_04138	ENOG4105BZP	glycoside hydrolase 15-related
AA314_04141	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
AA314_04142	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
AA314_04143	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
AA314_04144	ENOG4105CHR	reductase
AA314_04145	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
AA314_04146	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
AA314_04147	ENOG4108YZG	isomerase
AA314_04148	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
AA314_04149	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
AA314_04150	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
AA314_04151	ENOG4108KIH	Inherit from NOG: halimadienyl-diphosphate synthase activity
AA314_04160	ENOG4105JZI	cytochrome P450
AA314_04164	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
AA314_04165	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
AA314_04166	ENOG4105M7K	Involved in the transcription termination process (By similarity)
AA314_04169	ENOG4105CBS	Chea signal transduction histidine kinase
AA314_04170	ENOG4108V3W	Chemotaxis protein, CheW
AA314_04171	ENOG4108V3W	Chemotaxis protein, CheW
AA314_04173	ENOG4105BZU	Histidine kinase
AA314_04174	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
AA314_04176	ENOG4108FKH	Transglycosylase SLT domain
AA314_04179	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
AA314_04187	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
AA314_04188	ENOG4108VYJ	response regulator receiver protein
AA314_04189	ENOG4105C8T	Leucyl-tRNA synthetase
AA314_04193	ENOG4105DXN	mazG family
AA314_04195	ENOG4108UJG	
AA314_04197	ENOG4105CTJ	Metal Dependent Phosphohydrolase
AA314_04198	ENOG4108Z2K	Cupin 2, conserved barrel domain protein
AA314_04203	ENOG4105EMN	RNA polymerase sigma factor
AA314_04205	ENOG4105CRK	lysyL-tRNA synthetase
AA314_04206	ENOG4105D60	lipoprotein releasing system transmembrane protein
AA314_04207	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
AA314_04208	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AA314_04210	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AA314_04211	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
AA314_04212	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AA314_04216	ENOG41081FY	multiple antibiotic resistance (MarC)-related
AA314_04218	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AA314_04222	ENOG4108Z7F	N-acetyltransferase
AA314_04224	ENOG4105D0C	transport protein
AA314_04225	ENOG4105XYF	acetyltransferase
AA314_04227	ENOG4105BZ1	(ABC) transporter
AA314_04229	ENOG4105D4Y	metalloprotease
AA314_04230	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
AA314_04232	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
AA314_04233	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
AA314_04234	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
AA314_04236	ENOG4105DSJ	YicC domain protein
AA314_04237	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
AA314_04238	ENOG4108SPH	protein kinase (EC 2.7.11.1)
AA314_04240	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
AA314_04243	ENOG4105JFG	SpoIID LytB domain protein
AA314_04245	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
AA314_04248	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
AA314_04249	ENOG4108JIS	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
AA314_04251	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
AA314_04258	ENOG4105C9M	aspartyl-trna synthetase
AA314_04259	ENOG4105CBD	Diacylglycerol kinase
AA314_04261	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AA314_04262	ENOG4105E0F	Histidine kinase
AA314_04263	ENOG4105CHH	sulfate transporter
AA314_04265	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
AA314_04266	ENOG4108SPH	protein kinase (EC 2.7.11.1)
AA314_04275	ENOG4105C98	muts2 protein
AA314_04277	ENOG4105C0D	helicase
AA314_04279	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
AA314_04281	ENOG4107ZE5	PPIases accelerate the folding of proteins
AA314_04282	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
AA314_04286	ENOG4105CSU	acyl-Coa dehydrogenase
AA314_04291	ENOG4105SG9	biopolymer transport protein, ExbD
AA314_04292	ENOG4105CWK	Biopolymer transport protein, ExbB
AA314_04297	ENOG4108JQ7	(ABC) transporter
AA314_04313	ENOG4105HZM	Fha domain containing protein
AA314_04315	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
AA314_04317	ENOG4108KXV	response regulator
AA314_04318	ENOG4105CTB	Polyprenyl synthetase
AA314_04319	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
AA314_04320	ENOG4105DX0	Hemolysin A
AA314_04324	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
AA314_04328	ENOG4105CDV	Ompa motb domain protein
AA314_04336	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
AA314_04338	ENOG4108URH	decarboxylase
AA314_04339	ENOG4108IYU	L-aspartate oxidase
AA314_04340	ENOG4105E4C	Lytic transglycosylase catalytic
AA314_04342	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
AA314_04343	ENOG4105MFV	ABC-2 type transporter
AA314_04344	ENOG4105EY8	ABC transporter
AA314_04347	ENOG4107RGC	Glycosyl transferase, family 2
AA314_04353	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
AA314_04355	ENOG4107RGC	Glycosyl transferase, family 2
AA314_04356	ENOG4107U9T	Pfam:Ribonuclease_BN
AA314_04357	ENOG4105C5H	ABC transporter
AA314_04363	ENOG4105EYW	Ion transport protein
AA314_04366	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
AA314_04373	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
AA314_04378	ENOG4105CPP	Dehydrogenase, E1 component
AA314_04379	ENOG4107RUY	(E1 component), alpha subunit
AA314_04380	ENOG4107R4J	Chloride channel
AA314_04381	ENOG4105BZU	Histidine kinase
AA314_04382	ENOG4107SGM	protein serine threonine phosphatase
AA314_04385	ENOG4105D05	Receptor
AA314_04387	ENOG4108SPH	protein kinase (EC 2.7.11.1)
AA314_04392	ENOG4105IH7	synthase
AA314_04394	ENOG4108PBA	serine threonine protein kinase
AA314_04396	ENOG41068W2	Cytochrome p-450
AA314_04398	ENOG4108M24	von Willebrand factor, type A
AA314_04399	ENOG4105UM3	Inherit from NOG: serine threonine phosphoprotein phosphatase
AA314_04400	ENOG4106E1W	protein with protein kinase and helix-hairpin-helix DNA-binding
AA314_04403	ENOG4107RRE	RNA-directed DNA polymerase
AA314_04404	ENOG4107RRE	RNA-directed DNA polymerase
AA314_04409	ENOG4105X17	23-dihydro-2,3-dihydroxybenzoate dehydrogenase
AA314_04410	ENOG4105E4F	Isochorismate synthase
AA314_04411	ENOG4108IQC	2,3-dihydroxybenzoate-AMP ligase
AA314_04412	ENOG4105WQI	isochorismatase
AA314_04413	ENOG4105CEY	Amp-dependent synthetase and ligase
AA314_04415	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
AA314_04424	ENOG4105TS0	gtp-binding protein
AA314_04430	ENOG4105CNA	YD repeat protein
AA314_04430	ENOG4105CNA	YD repeat protein
AA314_04441	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
AA314_04444	ENOG4105BZU	Histidine kinase
AA314_04447	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
AA314_04448	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
AA314_04451	ENOG4105CBT	Fructose-1,6-bisphosphatase
AA314_04455	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
AA314_04456	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
AA314_04458	ENOG4105CS2	ec 3.2.1.21
AA314_04464	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
AA314_04466	ENOG4105BZU	Histidine kinase
AA314_04477	ENOG410802X	bacteriophage n4 adsorption protein b
AA314_04480	ENOG4105C0H	protease
AA314_04484	ENOG4105E7W	lamb ycsf family protein
AA314_04485	ENOG4107RGD	Major Facilitator superfamily
AA314_04487	ENOG4105P4J	Allophanate hydrolase, subunit 1
AA314_04488	ENOG4105CFM	UPF0317 protein
AA314_04490	ENOG4105CVI	Transcriptional regulator
AA314_04493	ENOG4105D9P	serine threonine protein kinase
AA314_04494	ENOG4105CQ7	ATP-dependent helicase
AA314_04497	ENOG4106A3M	Cytochrome p-450
AA314_04501	ENOG4108RB3	Capsular polysaccharide biosynthesis protein
AA314_04505	ENOG4105BZU	Histidine kinase
AA314_04531	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AA314_04534	ENOG4107UCJ	Catalyzes the synthesis of activated sulfate (By similarity)
AA314_04535	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
AA314_04539	ENOG4108ZF3	Phosphatase
AA314_04542	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
AA314_04543	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
AA314_04545	ENOG4105FRY	Dehydrogenase
AA314_04546	ENOG4105EQ5	D-Lysine 5,6-aminomutase alpha subunit
AA314_04548	ENOG4107CHF	5,6-aminomutase beta subunit
AA314_04549	ENOG4108UYI	beta-alanyl-CoA ammonia lyase
AA314_04550	ENOG4105DE9	3-keto-5-aminohexanoate cleavage enzyme
AA314_04552	ENOG4105CHU	acetyl-coa acetyltransferase
AA314_04553	ENOG4108RZE	Tetr family transcriptional regulator
AA314_04554	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
AA314_04555	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
AA314_04559	ENOG4105E6M	Sulphatase-modifying factor protein
AA314_04577	ENOG4105CQZ	Histidine kinase
AA314_04578	ENOG4105BZU	Histidine kinase
AA314_04581	ENOG4105CNG	UPF0061 protein
AA314_04583	ENOG4105BZU	Histidine kinase
AA314_04602	ENOG4107QX3	carboxylase
AA314_04611	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
AA314_04615	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
AA314_04617	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
AA314_04619	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
AA314_04620	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
AA314_04621	ENOG41082KK	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
AA314_04622	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
AA314_04623	ENOG4105K8N	protein family UPF0079, ATPase
AA314_04627	ENOG4108KXV	response regulator
AA314_04628	ENOG4105BZU	Histidine kinase
AA314_04630	ENOG4105CI2	imidazolone-5-propionate hydrolase
AA314_04631	ENOG4105CGP	Urocanate hydratase
AA314_04632	ENOG4105CDH	Citrulline--aspartate ligase
AA314_04636	ENOG4105CY0	Metallo-Beta-Lactamase
AA314_04644	ENOG4105DA4	cytochrome c-type biogenesis protein
AA314_04645	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
AA314_04647	ENOG41060IM	Heme exporter protein
AA314_04649	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
AA314_04654	ENOG4107EF8	Glycosyl transferase (Group 1
AA314_04668	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
AA314_04669	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
AA314_04676	ENOG4105BZU	Histidine kinase
AA314_04683	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
AA314_04687	ENOG4105EHU	Circadian clock protein KaiC
AA314_04689	ENOG4105ETX	regulatoR
AA314_04691	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
AA314_04692	ENOG4105D7N	magnesium and cobalt transport protein CorA
AA314_04698	ENOG4105DR4	Methyltransferase
AA314_04715	ENOG4105E55	glycerol-3-phosphate acyltransferase
AA314_04716	ENOG4105C75	arginyL-tRNA synthetase
AA314_04718	ENOG4105BZU	Histidine kinase
AA314_04720	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
AA314_04723	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
AA314_04724	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
AA314_04725	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
AA314_04726	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
AA314_04728	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
AA314_04729	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
AA314_04730	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
AA314_04731	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AA314_04732	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
AA314_04733	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
AA314_04734	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
AA314_04735	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
AA314_04736	ENOG4108BAG	50s ribosomal protein l29
AA314_04737	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
AA314_04738	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
AA314_04739	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
AA314_04741	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
AA314_04742	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
AA314_04743	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
AA314_04744	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
AA314_04745	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
AA314_04746	ENOG41087MT	50S ribosomal protein L30
AA314_04747	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
AA314_04749	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
AA314_04750	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
AA314_04752	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
AA314_04753	ENOG41067V7	50S ribosomal protein L36
AA314_04754	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AA314_04755	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
AA314_04756	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
AA314_04757	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AA314_04758	ENOG4108ZT0	50S ribosomal protein l17
AA314_04764	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AA314_04765	ENOG4108594	Permease of the drug metabolite transporter
AA314_04767	ENOG4105D53	Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity)
AA314_04775	ENOG4107SC1	transglycosylase
AA314_04781	ENOG4105BZU	Histidine kinase
AA314_04784	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
AA314_04791	ENOG4105FFC	UPF0187 protein
AA314_04795	ENOG4105DHG	Allantoate amidinohydrolase
AA314_04796	ENOG4105VT2	5-hydroxyisourate hydrolase
AA314_04797	ENOG4108Z2U	ureidoglycolate hydrolase
AA314_04799	ENOG4108XNJ	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
AA314_04800	ENOG4108YZ9	Urea amidohydrolase subunit gamma
AA314_04801	ENOG4105CQM	Urea amidohydrolase subunit alpha
AA314_04803	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
AA314_04804	ENOG4106IPI	cyclase, family
AA314_04811	ENOG4105BZU	Histidine kinase
AA314_04817	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
AA314_04820	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
AA314_04822	ENOG4108IYI	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
AA314_04826	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
AA314_04827	ENOG4105CEV	competence damage-inducible protein
AA314_04828	ENOG4105IJJ	transcriptional regulator, crp fnr family
AA314_04830	ENOG4105CUB	amino acid
AA314_04831	ENOG4105C5S	asparaginyl-tRNA synthetase
AA314_04835	ENOG4105I8F	Histidine kinase
AA314_04842	ENOG4108UAJ	Transcriptional regulator
AA314_04853	ENOG4105BZU	Histidine kinase
AA314_04861	ENOG4105CDV	Ompa motb domain protein
AA314_04865	ENOG4105CXV	gliding motility protein
AA314_04867	ENOG4105DNE	Transposase
AA314_04869	ENOG4105D8V	Glucose sorbosone dehydrogenase
AA314_04872	ENOG4105C4X	radical SAM domain protein
AA314_04886	ENOG4108DT4	serine threonine protein kinase
AA314_04888	ENOG4105DNE	Transposase
AA314_04901	ENOG4105CDY	transcriptional regulatory protein
AA314_04904	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
AA314_04908	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AA314_04911	ENOG4105KNA	-acetyltransferase
AA314_04914	ENOG4105NVB	glycoside hydrolase, family 19
AA314_04921	ENOG41087PP	glycosyltransferase MGT family
AA314_04929	ENOG4105CUX	Signal transduction histidine kinase
AA314_04934	ENOG4105C84	Histidine ammonia-lyase
AA314_04935	ENOG4105CFH	Aspartokinase
AA314_04944	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AA314_04948	ENOG4105C4R	Atp-dependent dna helicase
AA314_04949	ENOG4105CFG	Acts as a chaperone (By similarity)
AA314_04952	ENOG4105DU1	integral membrane protein, terc
AA314_04953	ENOG4105D0M	Protease HtpX homolog
AA314_04955	ENOG4107B57	rieske 2fe-2S domain-containing protein
AA314_04959	ENOG4105CND	Glycosyl transferase, family 2
AA314_04963	ENOG4105CND	Glycosyl transferase, family 2
AA314_04970	ENOG4105CMR	udp-glucose 4-epimerase
AA314_04975	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
AA314_04976	ENOG4105CNT	hydrolase family 2
AA314_04979	ENOG4105BZ1	(ABC) transporter
AA314_04981	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
AA314_04983	ENOG4107JEE	Short-chain dehydrogenase reductase Sdr
AA314_04985	ENOG4105CHR	reductase
AA314_04995	ENOG4105EEQ	Na H antiporter
AA314_04996	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
AA314_04997	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
AA314_04999	ENOG4105EIP	mannose-6-phosphate isomerase
AA314_05004	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
AA314_05005	ENOG4105C3F	Signal peptidase i
AA314_05007	ENOG4105CXT	aspartate transcarbamylase
AA314_05009	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
AA314_05014	ENOG4108IQE	Amp-dependent synthetase and ligase
AA314_05015	ENOG4105BZN	citrate synthase
AA314_05016	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
AA314_05018	ENOG4105D49	3-dehydroquinate synthase
AA314_05019	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
AA314_05021	ENOG4105D49	3-dehydroquinate synthase
AA314_05022	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
AA314_05023	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
AA314_05024	ENOG4105E4F	Isochorismate synthase
AA314_05026	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
AA314_05028	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
AA314_05029	ENOG4105DTQ	mandelate racemase muconate lactonizing
AA314_05032	ENOG4105CZX	twitching motility protein
AA314_05033	ENOG4108SPH	protein kinase (EC 2.7.11.1)
AA314_05037	ENOG4105D29	Helix-turn-helix type 11 domain protein
AA314_05039	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
AA314_05040	ENOG4108HMX	isocitrate dehydrogenase (NADP)
AA314_05041	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
AA314_05043	ENOG4105E33	succinate dehydrogenase
AA314_05044	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
AA314_05045	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
AA314_05046	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
AA314_05047	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
AA314_05048	ENOG4105K5M	30s ribosomal protein S16
AA314_05049	ENOG4105VB6	UPF0109 protein
AA314_05050	ENOG41082N4	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
AA314_05051	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
AA314_05052	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
AA314_05054	ENOG41082RQ	UPF0102 protein
AA314_05058	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AA314_05061	ENOG4105CJR	Integral membrane protein (MviN
AA314_05062	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
AA314_05070	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
AA314_05074	ENOG4105BZU	Histidine kinase
AA314_05080	ENOG4105D9P	serine threonine protein kinase
AA314_05081	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AA314_05085	ENOG4108SPH	protein kinase (EC 2.7.11.1)
AA314_05086	ENOG4105BZU	Histidine kinase
AA314_05092	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
AA314_05101	ENOG4105CUJ	penicillin amidase
AA314_05114	ENOG4105CH6	catalase
AA314_05117	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
AA314_05119	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
AA314_05120	ENOG4105CHR	reductase
AA314_05125	ENOG4105CP2	von willebrand factor, type a
AA314_05131	ENOG4105VEQ	Cold shock protein
AA314_05134	ENOG4105CHR	reductase
AA314_05138	ENOG4108V1T	peptidylprolyl cis-trans isomerase
AA314_05143	ENOG4105C02	permease
AA314_05145	ENOG4105C22	threonyL-tRNA synthetase
AA314_05146	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
AA314_05147	ENOG4108A8W	50s ribosomal protein L35
AA314_05148	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
AA314_05149	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
AA314_05150	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
AA314_05151	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
AA314_05153	ENOG410624X	efflux transporter, rnd family, mfp subunit
AA314_05154	ENOG4108JJA	ABC, transporter
AA314_05158	ENOG4105C8Q	Methyl-accepting chemotaxis
AA314_05160	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
AA314_05164	ENOG4105C29	acyl-CoA thioesterase
AA314_05167	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
AA314_05168	ENOG4105E2Y	ABC, transporter
AA314_05175	ENOG4105CJ1	ABC, transporter
AA314_05182	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
AA314_05188	ENOG4105CZX	twitching motility protein
AA314_05192	ENOG4105NXH	GreA GreB family elongation factor
AA314_05206	ENOG4108V06	Glutathione peroxidase
AA314_05209	ENOG4108ZJ4	polysaccharide deacetylase
AA314_05225	ENOG4105D3Q	Sugar transferase
AA314_05227	ENOG4105C3M	thioredoxin reductase
AA314_05230	ENOG41062KD	Inherit from COG: ketosteroid isomerase-like protein
AA314_05231	ENOG4107S9F	NmrA family
AA314_05240	ENOG4108YBA	Histidine kinase
AA314_05241	ENOG4105C0W	non-ribosomal peptide synthetase
AA314_05243	ENOG4108YZY	peptidylprolyl cis-trans isomerase
AA314_05252	ENOG4106PBJ	Serine threonine-protein kinase Pkn6
AA314_05256	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
AA314_05257	ENOG41070F3	Catalyzes the ATP-dependent phosphorylation of maltose to maltose 1-phosphate. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, GlgE and GlgB (By similarity)
AA314_05259	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
AA314_05271	ENOG4105ES5	Histidine kinase
AA314_05274	ENOG4105BZU	Histidine kinase
AA314_05275	ENOG4107YX5	Pfam:DUF548
AA314_05276	ENOG4106855	Competence protein
AA314_05289	ENOG4105E53	ec 3.2.1.28
AA314_05290	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
AA314_05298	ENOG4105BZU	Histidine kinase
AA314_05301	ENOG4105BZU	Histidine kinase
AA314_05303	ENOG4105Q56	cytochrome P450
AA314_05313	ENOG4105C34	Pseudouridine synthase
AA314_05317	ENOG4108XHQ	(2Fe-2S)-binding domain protein
AA314_05320	ENOG4105C0D	helicase
AA314_05322	ENOG4105CR8	Transcriptional regulator
AA314_05323	ENOG4108Q5Y	Membrane
AA314_05332	ENOG4107KIA	Virulence factor Mce family protein
AA314_05337	ENOG4107UP5	Phosphatidylserine decarboxylase
AA314_05338	ENOG4105CUT	histidyl-tRNA synthetase
AA314_05347	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
AA314_05351	ENOG4105BZU	Histidine kinase
AA314_05352	ENOG4105BZU	Histidine kinase
AA314_05357	ENOG4105EAH	synthase
AA314_05358	ENOG4105EIE	fructose-bisphosphate aldolase
AA314_05367	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
AA314_05368	ENOG4105D5P	Methylmalonyl-coA mutase
AA314_05369	ENOG4107X35	defense response to bacterium
AA314_05376	ENOG4108HMN	Caspase domain
AA314_05381	ENOG4105E39	Enoyl-CoA hydratase
AA314_05382	ENOG4105BZU	Histidine kinase
AA314_05390	ENOG4105CJ1	ABC, transporter
AA314_05393	ENOG4105C08	Histidine kinase
AA314_05394	ENOG4105C9K	Endothelin-converting enzyme 1
AA314_05397	ENOG4105CIF	Ornithine Cyclodeaminase
AA314_05399	ENOG4105C26	Dehydrogenase
AA314_05401	ENOG4107AQZ	Membrane
AA314_05415	ENOG4105EYW	Ion transport protein
AA314_05418	ENOG4108HMN	Caspase domain
AA314_05423	ENOG4105CIR	epoxide hydrolase
AA314_05425	ENOG4107YPT	transcriptional regulator
AA314_05427	ENOG4108T5G	Adenylate
AA314_05431	ENOG4107QR7	peptidase S8 and S53, subtilisin, kexin, sedolisin
AA314_05432	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
AA314_05446	ENOG4107R95	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
AA314_05449	ENOG4108WC5	Alpha Beta Hydrolase Fold protein
AA314_05452	ENOG4108JQ1	Dehydrogenase
AA314_05462	ENOG4107QX3	carboxylase
AA314_05463	ENOG4105C1G	acyl-Coa dehydrogenase
AA314_05464	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
AA314_05466	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
AA314_05467	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
AA314_05470	ENOG4105M6F	mutator MutT protein
AA314_05472	ENOG4106PBJ	Serine threonine-protein kinase Pkn6
AA314_05475	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
AA314_05477	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
AA314_05478	ENOG4105CFG	Acts as a chaperone (By similarity)
AA314_05479	ENOG4108VD1	dedA family
AA314_05481	ENOG4108Z0R	Transferase
AA314_05482	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
AA314_05485	ENOG4105C2D	reductase
AA314_05488	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
AA314_05489	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
AA314_05490	ENOG4108IIH	CoA-transferase subunit B
AA314_05491	ENOG4105D6N	CoA-transferase, subunit a
AA314_05492	ENOG4105CHU	acetyl-coa acetyltransferase
AA314_05493	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
AA314_05494	ENOG4105C1G	acyl-Coa dehydrogenase
AA314_05496	ENOG4105C1G	acyl-Coa dehydrogenase
AA314_05497	ENOG4105E39	Enoyl-CoA hydratase
AA314_05498	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AA314_05501	ENOG4105D1F	ATP-binding protein
AA314_05514	ENOG4105K70	DNA-binding protein
AA314_05520	ENOG4105DUM	transcriptional regulator, lysR family
AA314_05524	ENOG4105CQ7	ATP-dependent helicase
AA314_05525	ENOG4105CQ7	ATP-dependent helicase
AA314_05526	ENOG4105RHY	Pfam:UPF0157
AA314_05529	ENOG4105EWM	Histidine kinase
AA314_05534	ENOG4106A3M	Cytochrome p-450
AA314_05536	ENOG4108ZXC	Two component transcriptional regulator, luxr family
AA314_05538	ENOG4105C28	cystathionine
AA314_05547	ENOG4105DA5	(ABC) transporter
AA314_05550	ENOG4105EP1	Efflux transporter rnd family, mfp subunit
AA314_05555	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
AA314_05559	ENOG4107QJQ	Mate efflux family protein
AA314_05563	ENOG4105BZU	Histidine kinase
AA314_05564	ENOG4105CHM	Aminotransferase
AA314_05565	ENOG4105CZ7	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
AA314_05567	ENOG4105CHR	reductase
AA314_05568	ENOG4105D29	Helix-turn-helix type 11 domain protein
AA314_05572	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
AA314_05575	ENOG4105BZU	Histidine kinase
AA314_05588	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
AA314_05600	ENOG4105BZU	Histidine kinase
AA314_05603	ENOG4107WP9	Histidine kinase
AA314_05604	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
AA314_05608	ENOG4107R7I	amino acid
AA314_05610	ENOG4105CSH	Transporter
AA314_05625	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AA314_05638	ENOG4105CKX	Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP
AA314_05641	ENOG4105EYW	Ion transport protein
AA314_05643	ENOG4105FE9	pseudouridine synthase
AA314_05644	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
AA314_05645	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
AA314_05646	ENOG4105C31	Tryptophanyl-tRNA synthetase
AA314_05650	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AA314_05655	ENOG4105D9P	serine threonine protein kinase
AA314_05659	ENOG4108XW1	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity (By similarity)
AA314_05660	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
AA314_05661	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
AA314_05666	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
AA314_05675	ENOG4108KNB	n-acetylmuramoyl-l-alanine amidase
AA314_05678	ENOG4105BZU	Histidine kinase
AA314_05679	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
AA314_05681	ENOG4105E08	Glycoside hydrolase, family 9
AA314_05682	ENOG4108KDT	Molybdate metabolism regulator
AA314_05684	ENOG4105BZU	Histidine kinase
AA314_05685	ENOG4105KKX	ATPase associated with various cellular activities aaa_5
AA314_05686	ENOG4105RD5	
AA314_05687	ENOG4105DEG	Vwa containing coxe family protein
AA314_05691	ENOG4105BZU	Histidine kinase
AA314_05693	ENOG4105DC7	peptidase M24
AA314_05697	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
AA314_05701	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
AA314_05702	ENOG4108MGY	Histidine kinase
AA314_05731	ENOG4105KCK	Peptidoglycan-associated lipoprotein
AA314_05736	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
AA314_05737	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
AA314_05741	ENOG4108UGD	Serine Threonine protein kinase
AA314_05750	ENOG4105CY3	ABC transporter, permease
AA314_05753	ENOG4105EMN	RNA polymerase sigma factor
AA314_05763	ENOG4107PE3	Mammalian cell entry related domain protein
AA314_05768	ENOG4108JUA	Transcriptional regulator
AA314_05769	ENOG4108IJ6	ABC transporter
AA314_05776	ENOG4105D9P	serine threonine protein kinase
AA314_05777	ENOG4105F8J	Adenylate Guanylate cyclase
AA314_05779	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
AA314_05780	ENOG4105GFR	rna polymerase sigma factor
AA314_05785	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
AA314_05786	ENOG4108IXY	short-chain dehydrogenase reductase
AA314_05791	ENOG4105C5W	Aldolase
AA314_05795	ENOG4105CEY	Amp-dependent synthetase and ligase
AA314_05797	ENOG4105CGK	Exodeoxyribonuclease III
AA314_05798	ENOG4108UGD	Serine Threonine protein kinase
AA314_05800	ENOG4105CPC	Aldo Keto reductase
AA314_05805	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
AA314_05807	ENOG4105F2Z	3-oxoadipate enol-lactonase
AA314_05808	ENOG4105CPC	Aldo Keto reductase
AA314_05816	ENOG4105C1G	acyl-Coa dehydrogenase
AA314_05817	ENOG4107XR4	alpha beta
AA314_05829	ENOG4105V9V	Short-chain dehydrogenase reductase Sdr
AA314_05842	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
AA314_05851	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
AA314_05853	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
AA314_05859	ENOG4107VAM	peptidase, m28
AA314_05860	ENOG4105CPC	Aldo Keto reductase
AA314_05866	ENOG4107QMS	site-determining protein
AA314_05870	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AA314_05874	ENOG4105C02	permease
AA314_05876	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
AA314_05877	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
AA314_05878	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
AA314_05879	ENOG4105CH7	arginosuccinase
AA314_05880	ENOG4105DBV	ornithine carbamoyltransferase
AA314_05884	ENOG4107RVU	D-Ala-D-Ala carboxypeptidase 3 (S13) family
AA314_05885	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
AA314_05889	ENOG4105CHM	Aminotransferase
AA314_05890	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
AA314_05891	ENOG4106H78	methyltransferase
AA314_05895	ENOG4105PGM	cation diffusion facilitator family transporter
AA314_05896	ENOG4108JUA	Transcriptional regulator
AA314_05898	ENOG4105CI3	gtp-binding protein typa
AA314_05901	ENOG4105CDY	transcriptional regulatory protein
AA314_05906	ENOG4105CA0	peroxidase
AA314_05907	ENOG4105R1U	AraC Family Transcriptional Regulator
AA314_05913	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
AA314_05917	ENOG41062BK	proline dehydrogenase
AA314_05929	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
AA314_05936	ENOG4105E4C	Lytic transglycosylase catalytic
AA314_05940	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
AA314_05943	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AA314_05944	ENOG4105EPD	Oligopeptide transporter, Opt family
AA314_05951	ENOG4105CPI	Metal Dependent Phosphohydrolase
AA314_05952	ENOG4105CVN	desaturase
AA314_05954	ENOG4105C34	Pseudouridine synthase
AA314_05957	ENOG4107R21	site-determining protein
AA314_05960	ENOG4105C1Y	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis (By similarity)
AA314_05961	ENOG4105E4C	Lytic transglycosylase catalytic
AA314_05962	ENOG4105BZU	Histidine kinase
AA314_05965	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
AA314_05968	ENOG4107QPV	Serine Threonine protein kinase
AA314_05972	ENOG4105C5H	ABC transporter
AA314_05973	ENOG4105D9P	serine threonine protein kinase
AA314_05976	ENOG4105CAT	Cytidine monophosphate kinase
AA314_05977	ENOG4105CIH	Imidazole acetol-phosphate transaminase
AA314_05978	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
AA314_05983	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AA314_05987	ENOG4105CYN	Serine protein kinase
AA314_05990	ENOG4105CFG	Acts as a chaperone (By similarity)
AA314_05992	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
AA314_05995	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
AA314_05998	ENOG4107T1U	Catalyzes the synthesis of activated sulfate (By similarity)
AA314_06001	ENOG41084XP	SirA-like domain-containing protein
AA314_06002	ENOG4105D06	uba thif-type nad fad binding protein
AA314_06004	ENOG4105BZU	Histidine kinase
AA314_06010	ENOG4105EJ2	Transcriptional regulator
AA314_06016	ENOG4105CPF	Cell wall formation (By similarity)
AA314_06019	ENOG4105D52	delta-aminolevulinic acid dehydratase
AA314_06021	ENOG4105CIG	ABC transporter
AA314_06024	ENOG41060K3	Methyltransferase
AA314_06028	ENOG4105BZU	Histidine kinase
AA314_06029	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
AA314_06030	ENOG4105CBS	Chea signal transduction histidine kinase
AA314_06031	ENOG4108QAF	Methyl-accepting chemotaxis sensory transducer
AA314_06032	ENOG4106WCA	Frizzy aggregation protein FrzB
AA314_06033	ENOG4106FIA	frizzy aggregation protein A
AA314_06034	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AA314_06037	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
AA314_06038	ENOG4105DCF	alanine dehydrogenase
AA314_06039	ENOG4105EMN	RNA polymerase sigma factor
AA314_06043	ENOG4106PBJ	Serine threonine-protein kinase Pkn6
AA314_06047	ENOG4108194	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
AA314_06048	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
AA314_06049	ENOG4105D6E	homoserine dehydrogenase
AA314_06055	ENOG4105EA8	2-Nitropropane dioxygenase
AA314_06057	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
AA314_06059	ENOG4105DWV	Homoserine O-trans-acetylase
AA314_06060	ENOG4105DBI	uridine monophosphokinase
AA314_06062	ENOG4105E18	UPF0276 protein
AA314_06065	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
AA314_06066	ENOG4105EMN	RNA polymerase sigma factor
AA314_06067	ENOG4105MD1	YeeE YedE family protein
AA314_06071	ENOG4105CYC	Transferase
AA314_06072	ENOG4105BZU	Histidine kinase
AA314_06074	ENOG4105CPQ	Dehydrogenase
AA314_06079	ENOG4108URH	decarboxylase
AA314_06080	ENOG4108JA5	May be involved in signal transduction. Participates in the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria, via its interaction with KaiC. Required for robustness of the circadian rhythm of gene expression and is involved in clock outputs (By similarity)
AA314_06085	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
AA314_06086	ENOG4108Z5K	methylglyoxal synthase
AA314_06105	ENOG4107QHF	type ii secretion system protein e
AA314_06106	ENOG4105F6U	Short-chain dehydrogenase reductase Sdr
AA314_06107	ENOG4105EXG	Transcriptional regulator
AA314_06113	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
AA314_06122	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
AA314_06123	ENOG4105CC0	LysR family Transcriptional regulator
AA314_06129	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
AA314_06132	ENOG4105JZI	cytochrome P450
AA314_06133	ENOG4107QHF	type ii secretion system protein e
AA314_06138	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AA314_06139	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AA314_06140	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AA314_06144	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AA314_06151	ENOG4105CQZ	Histidine kinase
AA314_06162	ENOG4105CGH	5'-nucleotidase
AA314_06167	ENOG4105D9P	serine threonine protein kinase
AA314_06169	ENOG4106ZTA	Carotenogenesis protein CarS
AA314_06170	ENOG4106SST	carotenogenesis protein carR
AA314_06171	ENOG4105WH9	RNA polymerase
AA314_06173	ENOG4105BZU	Histidine kinase
AA314_06174	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
AA314_06179	ENOG4108JUA	Transcriptional regulator
AA314_06181	ENOG4108V5V	Serine Threonine protein kinase
AA314_06186	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
AA314_06188	ENOG4105EHZ	conserved protein UCP016719
AA314_06189	ENOG4108V5V	Serine Threonine protein kinase
AA314_06191	ENOG4105C98	muts2 protein
AA314_06196	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
AA314_06198	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
AA314_06199	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
AA314_06201	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
AA314_06203	ENOG4107QSN	dihydrolipoamide acetyltransferase
AA314_06204	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
AA314_06210	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
AA314_06211	ENOG4105DR5	peptidase
AA314_06219	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
AA314_06220	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
AA314_06221	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
AA314_06222	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
AA314_06224	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
AA314_06225	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
AA314_06226	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
AA314_06227	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
AA314_06228	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
AA314_06230	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
AA314_06232	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
AA314_06236	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AA314_06237	ENOG4105BZU	Histidine kinase
AA314_06238	ENOG4106322	response regulator
AA314_06239	ENOG4108TQ9	Histidine kinase
AA314_06240	ENOG4105UYK	outer membrane protein a
AA314_06242	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
AA314_06243	ENOG4105F1J	Homogentisate 1,2-dioxygenase
AA314_06251	ENOG4105EQ2	LysR family Transcriptional regulator
AA314_06252	ENOG4105CHJ	isochorismatase hydrolase
AA314_06253	ENOG4105JQN	Transcriptional regulator
AA314_06254	ENOG4105EQ2	LysR family Transcriptional regulator
AA314_06262	ENOG4105D82	Glutamate dehydrogenase
AA314_06265	ENOG4105C0H	protease
AA314_06266	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AA314_06271	ENOG4105D9P	serine threonine protein kinase
AA314_06273	ENOG4105KWW	Biogenesis protein
AA314_06283	ENOG4105CHW	UPF0052 protein
AA314_06285	ENOG4107YJ4	chain length determinant protein
AA314_06290	ENOG4108JUA	Transcriptional regulator
AA314_06291	ENOG4107TT5	NLP P60 protein
AA314_06298	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
AA314_06302	ENOG4108PBA	serine threonine protein kinase
AA314_06303	ENOG4105D9P	serine threonine protein kinase
AA314_06309	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AA314_06311	ENOG4105VEQ	Cold shock protein
AA314_06320	ENOG4105EMN	RNA polymerase sigma factor
AA314_06325	ENOG4108535	NAD dependent epimerase/dehydratase family
AA314_06328	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AA314_06329	ENOG4105BZU	Histidine kinase
AA314_06333	ENOG4105D3G	Pseudouridine synthase
AA314_06338	ENOG4105CJ1	ABC, transporter
AA314_06339	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
AA314_06340	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
AA314_06341	ENOG4105KME	endoribonuclease L-psp
AA314_06342	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
AA314_06345	ENOG4105D9P	serine threonine protein kinase
AA314_06348	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AA314_06351	ENOG4105C0A	alcohol dehydrogenase
AA314_06356	ENOG4105CFG	Acts as a chaperone (By similarity)
AA314_06360	ENOG4108IAB	Phoh family
AA314_06361	ENOG4108RRZ	Transcription elongation factor GreB
AA314_06364	ENOG4107ZBH	radical SAM domain protein
AA314_06370	ENOG4105EBR	Carboxylesterase
AA314_06374	ENOG4105CHR	reductase
AA314_06375	ENOG410901E	Membrane
AA314_06381	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AA314_06382	ENOG4107T94	Endo-14-beta-xylanase
AA314_06383	ENOG4105CHM	Aminotransferase
AA314_06386	ENOG4105BZU	Histidine kinase
AA314_06387	ENOG4107SM8	Adenylate Guanylate cyclase
AA314_06392	ENOG4105BZU	Histidine kinase
AA314_06410	ENOG4105EXC	Acyl-transferase
AA314_06411	ENOG4105CKW	Inner membrane protein yedI
AA314_06412	ENOG4105C9B	Cysteine desulfurase
AA314_06413	ENOG4108KPZ	tonB-dependent Receptor
AA314_06418	ENOG4105HEI	LysR family (Transcriptional regulator
AA314_06419	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
AA314_06427	ENOG4107SKW	Inherit from COG: Alpha beta hydrolase
AA314_06437	ENOG4105BZU	Histidine kinase
AA314_06441	ENOG4108JPV	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
AA314_06443	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
AA314_06444	ENOG4105CUK	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
AA314_06453	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
AA314_06454	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
AA314_06455	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
AA314_06456	ENOG4105C11	sulfate adenylyltransferase), subunit 2
AA314_06457	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
AA314_06458	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
AA314_06462	ENOG4107SM8	Adenylate Guanylate cyclase
AA314_06463	ENOG4107S2Z	UPF0761 membrane protein
AA314_06466	ENOG4105EYW	Ion transport protein
AA314_06469	ENOG4105D8V	Glucose sorbosone dehydrogenase
AA314_06470	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
AA314_06473	ENOG4105ETX	regulatoR
AA314_06479	ENOG4108T5G	Adenylate
AA314_06484	ENOG4108KF3	Electron transport protein SCO1 SenC
AA314_06492	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
AA314_06494	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AA314_06502	ENOG4105KHC	sulfurtransferase
AA314_06504	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
AA314_06510	ENOG4105VN1	Heat shock protein
AA314_06522	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
AA314_06525	ENOG4105VZ9	UPF0235 protein
AA314_06530	ENOG4105C2M	dna polymerase I
AA314_06533	ENOG4105GVR	general secretion pathway protein D
AA314_06538	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
AA314_06539	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
AA314_06540	ENOG4106PBJ	Serine threonine-protein kinase Pkn6
AA314_06541	ENOG4105D7K	pfkb domain protein
AA314_06542	ENOG410826D	Involved in DNA repair and RecF pathway recombination (By similarity)
AA314_06549	ENOG4107QR0	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AA314_06550	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AA314_06551	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
AA314_06552	ENOG4108VZM	50s ribosomal protein L10
AA314_06553	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
AA314_06554	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
AA314_06555	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
AA314_06557	ENOG41084ED	50S ribosomal protein L33
AA314_06558	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
AA314_06559	ENOG4105C2N	RNA methyltransferase TrmH family group 3
AA314_06567	ENOG4105CQ7	ATP-dependent helicase
AA314_06572	ENOG4108Z4U	Ferredoxin
AA314_06573	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
AA314_06575	ENOG4105C1G	acyl-Coa dehydrogenase
AA314_06579	ENOG4105EQ2	LysR family Transcriptional regulator
AA314_06580	ENOG4105DQ4	alcohol dehydrogenase
AA314_06583	ENOG4108ETH	Formylglycinamide ribotide synthetase
AA314_06585	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
AA314_06587	ENOG4107UA9	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) (By similarity)
AA314_06597	ENOG4105JFG	SpoIID LytB domain protein
AA314_06602	ENOG41062D9	Histidine kinase
AA314_06604	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
AA314_06605	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
AA314_06606	ENOG4105C7W	Xanthine dehydrogenase
AA314_06614	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AA314_06616	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
AA314_06618	ENOG4105SYT	Methylenetetrahydrofolate reductase
AA314_06620	ENOG4105D74	hydrolase
AA314_06622	ENOG4107RNH	Outer membrane receptor FepA
AA314_06624	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
AA314_06625	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
AA314_06626	ENOG4105BZU	Histidine kinase
AA314_06628	ENOG4105C28	cystathionine
AA314_06629	ENOG4105C28	cystathionine
AA314_06631	ENOG4105CFH	Aspartokinase
AA314_06637	ENOG4108DG9	Smr protein MutS2
AA314_06638	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
AA314_06639	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
AA314_06640	ENOG4106A3M	Cytochrome p-450
AA314_06641	ENOG4108BRW	Activates expression of the rhaSR operon in response to L-rhamnose (By similarity)
AA314_06647	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
AA314_06650	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
AA314_06654	ENOG4105C8Y	Acetylornithine aminotransferase
AA314_06655	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
AA314_06656	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
AA314_06657	ENOG4105DNE	Transposase
AA314_06658	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AA314_06660	ENOG4107QXI	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
AA314_06665	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
AA314_06669	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
AA314_06670	ENOG4105BZU	Histidine kinase
AA314_06671	ENOG4105C0H	protease
AA314_06672	ENOG4107RFW	hydrolase family 57
AA314_06674	ENOG4105E2K	Glycosyl transferase (Group 1
AA314_06675	ENOG4106EEU	Response regulator receiver domain
AA314_06678	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
AA314_06680	ENOG4105D1H	recombination factor protein RarA
AA314_06682	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
AA314_06683	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
AA314_06684	ENOG4105C3J	Cysteine desulfurase
AA314_06686	ENOG4108SPH	protein kinase (EC 2.7.11.1)
AA314_06689	ENOG4105D48	metallophosphoesterase
AA314_06690	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
AA314_06692	ENOG4108RAV	Conserved protein
AA314_06695	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
AA314_06699	ENOG41062D9	Histidine kinase
AA314_06700	ENOG4105BZU	Histidine kinase
AA314_06703	ENOG4105C1G	acyl-Coa dehydrogenase
AA314_06710	ENOG4108JA1	polyketide synthase
AA314_06710	ENOG4108JA1	polyketide synthase
AA314_06711	ENOG4107SQU	synthase
AA314_06714	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
AA314_06716	ENOG410812K	response regulator receiver protein
AA314_06717	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
AA314_06718	ENOG4108IQE	Amp-dependent synthetase and ligase
AA314_06719	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AA314_06720	ENOG4105CQB	FAD linked oxidase domain protein
AA314_06721	ENOG4105EUJ	GTP cyclohydrolase i
AA314_06727	ENOG4105DIK	(ABC) transporter
AA314_06735	ENOG4108HMN	Caspase domain
AA314_06736	ENOG4108HMN	Caspase domain
AA314_06739	ENOG4105CHJ	isochorismatase hydrolase
AA314_06740	ENOG4105W87	Cbs domain
AA314_06750	ENOG4108159	Pfam:UPF0005
AA314_06752	ENOG4105NZG	Ferredoxin
AA314_06754	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
AA314_06758	ENOG4105D3Q	Sugar transferase
AA314_06759	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
AA314_06760	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
AA314_06761	ENOG4105F1N	DNA alkylation repair
AA314_06762	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
AA314_06764	ENOG41067QW	Transcriptional regulator
AA314_06767	ENOG4105D9P	serine threonine protein kinase
AA314_06770	ENOG4108M8S	permease YjgP YjgQ family protein
AA314_06771	ENOG4105C12	Phosphoribosylglycinamide synthetase
AA314_06773	ENOG4105DC1	bifunctional purine biosynthesis protein purh
AA314_06774	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AA314_06776	ENOG4106PBJ	Serine threonine-protein kinase Pkn6
AA314_06777	ENOG4108SPH	protein kinase (EC 2.7.11.1)
AA314_06785	ENOG4105DWF	phosphomethylpyrimidine kinase
AA314_06787	ENOG4105BZU	Histidine kinase
AA314_06790	ENOG4105D9P	serine threonine protein kinase
AA314_06791	ENOG4105BZU	Histidine kinase
AA314_06792	ENOG4105BZU	Histidine kinase
AA314_06793	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AA314_06794	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AA314_06795	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AA314_06796	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AA314_06798	ENOG4105CP2	von willebrand factor, type a
AA314_06803	ENOG4107SCK	Monooxygenase
AA314_06805	ENOG4105C8Q	Methyl-accepting chemotaxis
AA314_06806	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
AA314_06810	ENOG4107QR7	peptidase S8 and S53, subtilisin, kexin, sedolisin
AA314_06815	ENOG4105C7K	acetolactate synthase
AA314_06816	ENOG4105DND	Transcriptional regulator
AA314_06817	ENOG4105CYC	Transferase
AA314_06820	ENOG4105C8Q	Methyl-accepting chemotaxis
AA314_06822	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
AA314_06825	ENOG4107EJC	Preprotein translocase subunit SecG
AA314_06826	ENOG4105CP7	Triose-phosphate isomerase
AA314_06827	ENOG4105BZA	Phosphoglycerate kinase
AA314_06830	ENOG4107YR5	Diacylglycerol kinase
AA314_06832	ENOG4105DZ0	fad dependent oxidoreductase
AA314_06835	ENOG4105VV6	START domain-containing protein
AA314_06836	ENOG4105EQI	Metal Dependent Phosphohydrolase
AA314_06838	ENOG4105F8V	Hydrolase, tatD family
AA314_06840	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
AA314_06847	ENOG4108MJI	response regulator
AA314_06848	ENOG4107R6F	Alpha Beta Hydrolase Fold protein
AA314_06855	ENOG4106A3M	Cytochrome p-450
AA314_06875	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
AA314_06882	ENOG4105EPU	Molybdenum cofactor synthesis domain protein
AA314_06884	ENOG4105DCG	PHP domain protein
AA314_06889	ENOG4105CFG	Acts as a chaperone (By similarity)
AA314_06891	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
AA314_06893	ENOG4108M5V	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
AA314_06894	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
AA314_06903	ENOG41074B2	UPF0747 protein
AA314_06904	ENOG4105CPK	Glycosyl transferase (Group 1
AA314_06915	ENOG4105E0R	Deoxyhypusine synthase
AA314_06917	ENOG4105DB7	PHP domain protein
AA314_06922	ENOG4108QAF	Methyl-accepting chemotaxis sensory transducer
AA314_06923	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AA314_06924	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AA314_06925	ENOG4105F8J	Adenylate Guanylate cyclase
AA314_06926	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AA314_06927	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AA314_06929	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
AA314_06930	ENOG41081QM	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AA314_06932	ENOG4105F8J	Adenylate Guanylate cyclase
AA314_06943	ENOG4105DE9	3-keto-5-aminohexanoate cleavage enzyme
AA314_06945	ENOG4107Z3H	Transcriptional regulator, TetR family
AA314_06947	ENOG4108IMY	Transcriptional regulator
AA314_06951	ENOG4108IDZ	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
AA314_06953	ENOG4105IJJ	transcriptional regulator, crp fnr family
AA314_06954	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
AA314_06955	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
AA314_06956	ENOG4105EWC	Purine nucleoside phosphorylase
AA314_06957	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
AA314_06960	ENOG4108RZE	Tetr family transcriptional regulator
AA314_06963	ENOG4105VB9	50S ribosomal protein l28
AA314_06964	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AA314_06967	ENOG4108K3A	Glutathione S-transferase
AA314_06968	ENOG4105CH2	amidohydrolase
AA314_06970	ENOG4105EUB	pirin domain protein
AA314_06971	ENOG4108T3F	Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes
AA314_06974	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
AA314_06976	ENOG4105CXV	gliding motility protein
AA314_06977	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
AA314_06995	ENOG4105D94	Major Facilitator Superfamily
AA314_06999	ENOG4105EJQ	L-serine dehydratase
AA314_07009	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
AA314_07022	ENOG4105CIR	epoxide hydrolase
AA314_07023	ENOG4105DM4	PTS System
AA314_07024	ENOG4105DE4	1-phosphofructokinase
AA314_07025	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
AA314_07026	ENOG4107B7Y	DNA-binding transcriptional regulator FruR
AA314_07027	ENOG4105CPC	Aldo Keto reductase
AA314_07028	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AA314_07029	ENOG4105CC9	acyl-Coa dehydrogenase
AA314_07031	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
AA314_07032	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
AA314_07037	ENOG4105DFW	ABC transporter
AA314_07038	ENOG4105C2J	ABC transporter
AA314_07039	ENOG4107RNG	ABC transporter
AA314_07043	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
AA314_07055	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
AA314_07056	ENOG4105EMU	Dehydrogenase
AA314_07057	ENOG4107QQG	Dehydrogenase
AA314_07060	ENOG4108VWS	Yaeq family
AA314_07065	ENOG4108VD1	dedA family
AA314_07066	ENOG4105CBS	Chea signal transduction histidine kinase
AA314_07068	ENOG4108UXN	response regulator
AA314_07069	ENOG4105C8Q	Methyl-accepting chemotaxis
AA314_07070	ENOG4108KTQ	Methyltransferase
AA314_07072	ENOG4105D9P	serine threonine protein kinase
AA314_07077	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
AA314_07079	ENOG4108VYJ	response regulator receiver protein
AA314_07084	ENOG4105C7S	Dehydrogenase
AA314_07085	ENOG4105CPP	Dehydrogenase, E1 component
AA314_07086	ENOG4108JYK	Dehydrogenase
AA314_07094	ENOG4105CGH	5'-nucleotidase
AA314_07098	ENOG4107R72	Ceramidase
AA314_07100	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
AA314_07101	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
AA314_07102	ENOG4107QHF	type ii secretion system protein e
AA314_07106	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
AA314_07107	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
AA314_07108	ENOG4105CRE	cytochrome C
AA314_07110	ENOG4105K63	Thioredoxin
AA314_07113	ENOG4105CJW	magnesium transporter
AA314_07115	ENOG4105CNI	cell division protein FtsW
AA314_07116	ENOG4105CJN	penicillin-binding protein
AA314_07120	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
AA314_07125	ENOG4105BZU	Histidine kinase
AA314_07126	ENOG4108Z03	MAF-like protein
AA314_07127	ENOG4105DFA	alanine racemase domain protein
AA314_07136	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
AA314_07137	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
AA314_07140	ENOG4105C8N	cysteinyl-tRNA synthetase
AA314_07141	ENOG4108UW8	fha domain-containing protein
AA314_07143	ENOG4108VJ1	Transcriptional regulator (CarD family
AA314_07144	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
AA314_07149	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
AA314_07150	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
AA314_07154	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
AA314_07158	ENOG4107QPV	Serine Threonine protein kinase
AA314_07163	ENOG4107EMZ	glycosyl transferase family
AA314_07174	ENOG4105DUX	Transporter
AA314_07176	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
AA314_07179	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
AA314_07186	ENOG4106PBJ	Serine threonine-protein kinase Pkn6
AA314_07188	ENOG4107VXM	glycerophosphoryl diester phosphodiesterase
AA314_07190	ENOG4108S4H	thioesterase Superfamily protein
AA314_07191	ENOG4105BZU	Histidine kinase
AA314_07194	ENOG4105D06	uba thif-type nad fad binding protein
AA314_07196	ENOG4108SPH	protein kinase (EC 2.7.11.1)
AA314_07201	ENOG4105CVR	type I restriction-modification system
AA314_07202	ENOG4107XZC	Restriction modification system DNA (Specificity
AA314_07204	ENOG4107SCJ	type I restriction enzyme EcoKI subunit R
AA314_07207	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
AA314_07212	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
AA314_07217	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
AA314_07223	ENOG4105DZP	Membrane-associated zinc metalloprotease
AA314_07225	ENOG4108ZAF	Molybdopterin
AA314_07231	ENOG4105C8Q	Methyl-accepting chemotaxis
AA314_07233	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
AA314_07237	ENOG41072GX	Peptidase M22 Glycoprotease
AA314_07238	ENOG4105K6T	rare lipoprotein A
AA314_07239	ENOG4105DZP	Membrane-associated zinc metalloprotease
AA314_07240	ENOG4105KNE	Phosphatidate cytidylyltransferase
AA314_07242	ENOG4108PBA	serine threonine protein kinase
AA314_07243	ENOG4105C34	Pseudouridine synthase
AA314_07244	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
AA314_07246	ENOG4105DJ0	Poly(A) Polymerase
AA314_07248	ENOG4108K16	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
AA314_07249	ENOG4108K16	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
AA314_07252	ENOG4105BZN	citrate synthase
AA314_07253	ENOG4105JZI	cytochrome P450
AA314_07258	ENOG4105D9R	oxidoreductase
AA314_07259	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
AA314_07265	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
AA314_07268	ENOG4107SFQ	iron-sulfur binding
AA314_07270	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
AA314_07271	ENOG4105E2Q	3-(3-hydroxy-phenyl)propionate hydroxylase
AA314_07275	ENOG4107RSM	transcriptional regulator
AA314_07276	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
AA314_07285	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
AA314_07291	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
AA314_07292	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
AA314_07293	ENOG4108Z66	YbaK ebsC protein
AA314_07295	ENOG4105E2A	Dehydrogenase
AA314_07296	ENOG4107R6F	Alpha Beta Hydrolase Fold protein
AA314_07297	ENOG4105BZU	Histidine kinase
AA314_07305	ENOG4105CUV	Homoserine Kinase
AA314_07315	ENOG4108YYC	ycei family
AA314_07316	ENOG4105CC0	LysR family Transcriptional regulator
AA314_07317	ENOG4105EUB	pirin domain protein
AA314_07320	ENOG41061HS	cysteine-type endopeptidase activity
AA314_07321	ENOG4105CA0	peroxidase
AA314_07327	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
AA314_07334	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
AA314_07335	ENOG4105HEI	LysR family (Transcriptional regulator
AA314_07344	ENOG4107QHF	type ii secretion system protein e
AA314_07345	ENOG4105D7Q	type ii secretion system
AA314_07347	ENOG4108VAU	general secretion pathway protein G
AA314_07350	ENOG4105X5Z	General secretion pathway protein I
AA314_07359	ENOG4105CZH	peptidase
AA314_07361	ENOG4108JMX	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
AA314_07363	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AA314_07365	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AA314_07369	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
AA314_07370	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
AA314_07371	ENOG4105D9P	serine threonine protein kinase
AA314_07373	ENOG4105M2J	Glutaredoxin
AA314_07374	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
AA314_07385	ENOG4105EEM	helicase
AA314_07389	ENOG4105CVA	phosphate
AA314_07393	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
AA314_07402	ENOG4107QPV	Serine Threonine protein kinase
AA314_07403	ENOG4105F8J	Adenylate Guanylate cyclase
AA314_07404	ENOG4108YQE	rare lipoprotein a
AA314_07410	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AA314_07411	ENOG4105D9P	serine threonine protein kinase
AA314_07424	ENOG4108UW8	fha domain-containing protein
AA314_07431	ENOG4107QWE	)-transporter
AA314_07443	ENOG4105D00	flagellar biosynthetic protein flhB
AA314_07444	ENOG4105D00	flagellar biosynthetic protein flhB
AA314_07445	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
AA314_07446	ENOG4105VS8	Flagellar biosynthetic protein fliq
AA314_07447	ENOG4105CN7	Flagellar biosynthetic protein FliP
AA314_07449	ENOG4105DD5	Flagellar motor switch protein
AA314_07453	ENOG4105W2B	Flagellar assembly protein
AA314_07457	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AA314_07464	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AA314_07471	ENOG4108M8H	domain protein
AA314_07475	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
AA314_07484	ENOG4107WJM	-acetyltransferase
AA314_07486	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
AA314_07492	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
AA314_07493	ENOG4105C1J	atp-dependent rna helicase
AA314_07494	ENOG4105C5H	ABC transporter
AA314_07496	ENOG4105C5H	ABC transporter
AA314_07499	ENOG4105CQB	FAD linked oxidase domain protein
AA314_07502	ENOG4108YZY	peptidylprolyl cis-trans isomerase
AA314_07503	ENOG4105CK2	sodium dicarboxylate symporter
AA314_07508	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AA314_07514	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
AA314_07516	ENOG4107R6F	Alpha Beta Hydrolase Fold protein
AA314_07519	ENOG4105C1G	acyl-Coa dehydrogenase
AA314_07520	ENOG4105DY8	decarboxylase
AA314_07533	ENOG4108ZF3	Phosphatase
AA314_07543	ENOG4105C0H	protease
AA314_07545	ENOG4105EYW	Ion transport protein
AA314_07546	ENOG4105F8J	Adenylate Guanylate cyclase
AA314_07549	ENOG4105DFM	M18 family aminopeptidase
AA314_07557	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AA314_07559	ENOG4105EMN	RNA polymerase sigma factor
AA314_07567	ENOG4105D7W	serine acetyltransferase
AA314_07573	ENOG4106PBJ	Serine threonine-protein kinase Pkn6
AA314_07578	ENOG4108UGD	Serine Threonine protein kinase
AA314_07580	ENOG4107EPV	Aminotransferase class V
AA314_07582	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
AA314_07584	ENOG4105M08	Membrane
AA314_07586	ENOG4105BZU	Histidine kinase
AA314_07587	ENOG4105BZU	Histidine kinase
AA314_07588	ENOG4105BZU	Histidine kinase
AA314_07590	ENOG4105CCT	upf0313 protein
AA314_07592	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
AA314_07595	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
AA314_07603	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
AA314_07604	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
AA314_07605	ENOG4105CBS	Chea signal transduction histidine kinase
AA314_07605	ENOG4105CBS	Chea signal transduction histidine kinase
AA314_07606	ENOG4105C8Q	Methyl-accepting chemotaxis
AA314_07608	ENOG4105BZU	Histidine kinase
AA314_07613	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
AA314_07615	ENOG4105C0A	alcohol dehydrogenase
AA314_07620	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
AA314_07623	ENOG4105BZU	Histidine kinase
AA314_07625	ENOG4107FW0	short-chain dehydrogenase reductase
AA314_07627	ENOG4105C02	permease
AA314_07639	ENOG410870F	Cyclic nucleotide-binding protein
AA314_07642	ENOG4105C3F	Signal peptidase i
AA314_07645	ENOG4106855	Competence protein
AA314_07663	ENOG4107QR7	peptidase S8 and S53, subtilisin, kexin, sedolisin
AA314_07669	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
AA314_07676	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
AA314_07681	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
AA314_07682	ENOG4105CIS	alcohol dehydrogenase
AA314_07683	ENOG4108NQ3	Phosphatidylinositol-specific phospholipase C
AA314_07686	ENOG4105DN3	alpha-2-macroglobulin domain protein
AA314_07687	ENOG4108JQB	penicillin-binding protein 1C
AA314_07688	ENOG4105I4A	GCN5-related N-acetyltransferase
AA314_07689	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
AA314_07698	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
AA314_07703	ENOG4105WD1	Membrane
AA314_07704	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
AA314_07712	ENOG4105DIH	basic membrane
AA314_07717	ENOG4105N6Y	Thioredoxin
AA314_07718	ENOG4105VCD	cytoplasmic protein
AA314_07719	ENOG4105D22	carbon starvation protein
AA314_07721	ENOG4105CZX	twitching motility protein
AA314_07741	ENOG4107R95	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
AA314_07749	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
AA314_07750	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
AA314_07751	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
AA314_07752	ENOG4105EE1	crotonyl-CoA reductase
AA314_07758	ENOG41088CQ	domain protein
AA314_07761	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
AA314_07764	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
AA314_07767	ENOG4105DRS	transport system, permease
AA314_07768	ENOG4105EQ7	Binding-protein-dependent transport systems, inner membrane component
AA314_07773	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
AA314_07787	ENOG4105C1G	acyl-Coa dehydrogenase
AA314_07788	ENOG4107QX3	carboxylase
AA314_07790	ENOG41069D7	Methyl-accepting chemotaxis
AA314_07791	ENOG4105C26	Dehydrogenase
AA314_07797	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
AA314_07801	ENOG4105CHR	reductase
AA314_07817	ENOG4108IXY	short-chain dehydrogenase reductase
AA314_07819	ENOG4105KVH	Transcriptional regulator
AA314_07820	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
AA314_07822	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
AA314_07830	ENOG4105UYK	outer membrane protein a
AA314_07834	ENOG4105CVK	Glutamate decarboxylase
AA314_07840	ENOG4105C0H	protease
AA314_07846	ENOG4105C8Q	Methyl-accepting chemotaxis
AA314_07858	ENOG4108SXK	Transporter Drug Metabolite Exporter family
AA314_07865	ENOG4108KPZ	tonB-dependent Receptor
AA314_07867	ENOG4108HMN	Caspase domain
AA314_07871	ENOG4105FQP	Beta-lactamase
AA314_07874	ENOG4105C83	adenylosuccinate lyase
AA314_07876	ENOG4105D9P	serine threonine protein kinase
AA314_07877	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
AA314_07878	ENOG4105DR5	peptidase
AA314_07880	ENOG4105EKQ	RNA-directed DNA polymerase
AA314_07882	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
AA314_07883	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
AA314_07884	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
AA314_07885	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
AA314_07887	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
AA314_07889	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
AA314_07893	ENOG4108ESY	Metal dependent phosphohydrolase
AA314_07895	ENOG4106PBJ	Serine threonine-protein kinase Pkn6
AA314_07897	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
AA314_07898	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
AA314_07899	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
AA314_07900	ENOG4105ZMH	deoxynucleoside kinase
AA314_07903	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
AA314_07904	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
AA314_07907	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
AA314_07909	ENOG4108ZF3	Phosphatase
AA314_07916	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
AA314_07917	ENOG4105BZU	Histidine kinase
AA314_07918	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AA314_07920	ENOG4105DGW	oligopeptidase A
AA314_07925	ENOG4107RSM	transcriptional regulator
AA314_07926	ENOG4105C5Z	peptidase
AA314_07943	ENOG4105BZS	acriflavin resistance protein
AA314_07944	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
AA314_07945	ENOG4105C28	cystathionine
AA314_07946	ENOG4105DR4	Methyltransferase
AA314_07949	ENOG4105FS0	cytoplasmic membrane protein
AA314_07951	ENOG4105DR4	Methyltransferase
AA314_07954	ENOG4105BZW	Glycerate kinase
AA314_07963	ENOG4105DAP	Nicotinate phosphoribosyltransferase
AA314_07969	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
AA314_07975	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
AA314_07983	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AA314_07984	ENOG4108VUG	Enoyl-CoA hydratase
AA314_07985	ENOG4106063	Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit
AA314_07986	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
AA314_07989	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
AA314_07990	ENOG4105D1H	recombination factor protein RarA
AA314_07994	ENOG4107R6D	beta-lactam binding protein AmpH
AA314_08003	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
AA314_08004	ENOG410812A	polypeptide-transport-associated domain protein, FtsQ-type
AA314_08005	ENOG4105CPF	Cell wall formation (By similarity)
AA314_08006	ENOG4105D4A	Cell wall formation (By similarity)
AA314_08007	ENOG4105DFU	Cell wall formation (By similarity)
AA314_08008	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
AA314_08009	ENOG4105CNI	cell division protein FtsW
AA314_08010	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
AA314_08011	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
AA314_08012	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
AA314_08013	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
AA314_08014	ENOG4105CJN	penicillin-binding protein
AA314_08015	ENOG41068JM	cell division protein, FtsL
AA314_08016	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
AA314_08018	ENOG4108V6E	Cell division protein mraZ
AA314_08021	ENOG4105C1G	acyl-Coa dehydrogenase
AA314_08031	ENOG4105C0A	alcohol dehydrogenase
AA314_08032	ENOG4105C5F	glutamine synthetase
AA314_08033	ENOG4105C26	Dehydrogenase
AA314_08034	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
AA314_08036	ENOG4106F5Q	Membrane
AA314_08038	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
AA314_08040	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
AA314_08041	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
AA314_08042	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
AA314_08044	ENOG4105C03	ribonuclease
AA314_08044	ENOG4105C03	ribonuclease
AA314_08045	ENOG4107S2Z	UPF0761 membrane protein
AA314_08046	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
AA314_08050	ENOG4105VS8	Flagellar biosynthetic protein fliq
AA314_08059	ENOG4108PYU	two-component system response regulator
AA314_08060	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AA314_08061	ENOG4108PBA	serine threonine protein kinase
AA314_08069	ENOG4105F0N	pyrophosphate phospho-hydrolase
AA314_08076	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AA314_08084	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
AA314_08088	ENOG410756H	nucleotidyltransferase
AA314_08094	ENOG4105CS6	Rhs element vgr protein
AA314_08095	ENOG4105CS6	Rhs element vgr protein
AA314_08098	ENOG4108PBA	serine threonine protein kinase
AA314_08109	ENOG4106PBJ	Serine threonine-protein kinase Pkn6
AA314_08110	ENOG4105CND	Glycosyl transferase, family 2
AA314_08111	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
AA314_08115	ENOG4105KCV	RNA signal recognition particle 4.5S RNA
AA314_08126	ENOG4108NEV	two component transcriptional regulator, LytTR family
AA314_08127	ENOG4108HRK	Histidine kinase
AA314_08128	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
AA314_08130	ENOG4108Z4X	TRANSCRIPTIONal
AA314_08131	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
AA314_08132	ENOG4106A3M	Cytochrome p-450
AA314_08137	ENOG4105D9P	serine threonine protein kinase
AA314_08145	ENOG4105CJW	magnesium transporter
AA314_08154	ENOG4105D64	Mechanosensitive ion channel
AA314_08155	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
AA314_08166	ENOG4108SPH	protein kinase (EC 2.7.11.1)
AA314_08169	ENOG4107R39	(ABC) transporter
AA314_08175	ENOG4107SYB	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
AA314_08179	ENOG4108JQ9	ABC transporter
AA314_08180	ENOG4105UIB	(ABC) transporter
AA314_08186	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
AA314_08187	ENOG4107T8T	UPF0173 metal-dependent hydrolase
AA314_08196	ENOG4105CVJ	phosphoglycerate mutase
AA314_08198	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
AA314_08206	ENOG4105CPF	Cell wall formation (By similarity)
AA314_08221	ENOG4105C5Q	Transcriptional regulator
AA314_08222	ENOG4105CH6	catalase
AA314_08223	ENOG4105JXB	ankyrin repeat-containing protein
AA314_08225	ENOG4105C22	threonyL-tRNA synthetase
AA314_08231	ENOG4105CN1	protease
AA314_08233	ENOG41063SB	peptidase
AA314_08234	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
AA314_08235	ENOG4105CAK	Cell division ATP-binding protein ftsE
AA314_08238	ENOG4105C8P	)-transporter
AA314_08241	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
AA314_08243	ENOG4105E02	MotA TolQ exbB proton channel
AA314_08244	ENOG4105SG9	biopolymer transport protein, ExbD
AA314_08247	ENOG4105CVR	type I restriction-modification system
AA314_08251	ENOG4107R33	ppx gppa phosphatase
AA314_08253	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AA314_08254	ENOG4108MUX	N-hydroxyarylamine O-acetyltransferase
AA314_08256	ENOG4105E39	Enoyl-CoA hydratase
AA314_08264	ENOG4108HMN	Caspase domain
AA314_08266	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AA314_08270	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
AA314_08271	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
AA314_08272	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
AA314_08275	ENOG4105E4G	Type IV pilus
AA314_08280	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AA314_08281	ENOG4105BZU	Histidine kinase
AA314_08282	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
AA314_08283	ENOG4106855	Competence protein
AA314_08285	ENOG4105DA5	(ABC) transporter
AA314_08287	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AA314_08288	ENOG4105BZU	Histidine kinase
AA314_08290	ENOG4105CZX	twitching motility protein
AA314_08291	ENOG4107QHF	type ii secretion system protein e
AA314_08292	ENOG4105DTN	riboflavin biosynthesis protein ribF
AA314_08293	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
AA314_08294	ENOG4105BZU	Histidine kinase
AA314_08305	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
AA314_08307	ENOG4105CFG	Acts as a chaperone (By similarity)
AA314_08310	ENOG4105BZU	Histidine kinase
AA314_08312	ENOG4106PVI	ATP-dependent carboxylate-amine ligase (By similarity)
AA314_08314	ENOG4105CN1	protease
AA314_08317	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
AA314_08318	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
AA314_08325	ENOG4108Q9H	CobQ/CobB/MinD/ParA nucleotide binding domain
AA314_08332	ENOG4105BZU	Histidine kinase
AA314_08334	ENOG4107QPV	Serine Threonine protein kinase
AA314_08339	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
AA314_08340	ENOG4105HHA	aminodeoxychorismate lyase
AA314_08343	ENOG4105BZU	Histidine kinase
AA314_08344	ENOG4105BZU	Histidine kinase
AA314_08345	ENOG4105BZU	Histidine kinase
AA314_08348	ENOG4105BZU	Histidine kinase
AA314_08349	ENOG4108KXV	response regulator
AA314_08352	ENOG4105BZU	Histidine kinase
AA314_08353	ENOG4108IUW	ABC transporter
AA314_08355	ENOG4105CYN	Serine protein kinase
AA314_08357	ENOG4105ED1	spovr family
AA314_08358	ENOG4105DR5	peptidase
AA314_08365	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
AA314_08366	ENOG4105E39	Enoyl-CoA hydratase
AA314_08368	ENOG4105C0B	DNA polymerase III (alpha subunit)
AA314_08371	ENOG4105CPC	Aldo Keto reductase
AA314_08373	ENOG4105BZU	Histidine kinase
AA314_08375	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
AA314_08389	ENOG4107TPY	serine threonine protein kinase
AA314_08390	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
AA314_08393	ENOG4106VK6	Flagellar motor protein
AA314_08396	ENOG4107V4F	S-adenosyl-l-methionine hydroxide adenosyltransferase
AA314_08402	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
AA314_08403	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
AA314_08418	ENOG4105EB3	Histidine kinase
AA314_08419	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
AA314_08420	ENOG4107R7I	amino acid
AA314_08421	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
AA314_08423	ENOG4107QN1	sodium solute
AA314_08424	ENOG4105KME	endoribonuclease L-psp
AA314_08428	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
AA314_08432	ENOG4105KCK	Peptidoglycan-associated lipoprotein
AA314_08442	ENOG4105GMB	type VI secretion system effector, hcp1 family
AA314_08446	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AA314_08451	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
AA314_08452	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
AA314_08454	ENOG4105CE4	GlcNAc 6-P deacetylase
AA314_08455	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
AA314_08457	ENOG4105EUB	pirin domain protein
AA314_08465	ENOG4105C8Y	Acetylornithine aminotransferase
AA314_08470	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
AA314_08481	ENOG4105CPC	Aldo Keto reductase
AA314_08485	ENOG4108RXX	maleylacetoacetate isomerase
AA314_08497	ENOG4107T8T	UPF0173 metal-dependent hydrolase
AA314_08502	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AA314_08506	ENOG4105CHP	RNA polymerase
AA314_08507	ENOG41067QW	Transcriptional regulator
AA314_08508	ENOG4105D82	Glutamate dehydrogenase
AA314_08509	ENOG4105C7B	Threonine dehydratase
AA314_08518	ENOG4105CHU	acetyl-coa acetyltransferase
AA314_08523	ENOG4105K63	Thioredoxin
AA314_08524	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
AA314_08526	ENOG4105CPC	Aldo Keto reductase
AA314_08527	ENOG4105C26	Dehydrogenase
AA314_08528	ENOG4105BZU	Histidine kinase
AA314_08529	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
AA314_08531	ENOG4105D3Q	Sugar transferase
AA314_08533	ENOG4105DWV	Homoserine O-trans-acetylase
AA314_08539	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
AA314_08539	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
AA314_08540	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
AA314_08542	ENOG4107SDU	Methyl-accepting chemotaxis
AA314_08546	ENOG4105CYM	Glutathione S-transferase
AA314_08553	ENOG4107FW0	short-chain dehydrogenase reductase
AA314_08554	ENOG4108JQC	penicillin-binding protein 1A
AA314_08555	ENOG4105EI2	Pseudouridine synthase
AA314_08558	ENOG4107T0X	DNA ligase
AA314_08567	ENOG4105C10	Electron transfer flavoprotein
AA314_08568	ENOG4105BZJ	Electron transfer flavoprotein
AA314_08569	ENOG4105C1G	acyl-Coa dehydrogenase
AA314_08570	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
AA314_08571	ENOG4105C2X	Arabinose 5-phosphate isomerase
AA314_08574	ENOG4105GFR	rna polymerase sigma factor
AA314_08578	ENOG4105D3G	Pseudouridine synthase
AA314_08581	ENOG4105JZI	cytochrome P450
AA314_08585	ENOG4106A3M	Cytochrome p-450
AA314_08590	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AA314_08591	ENOG4105ERH	Fumarylacetoacetate hydrolase
AA314_08592	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
AA314_08593	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
AA314_08595	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
AA314_08597	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
AA314_08598	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
AA314_08600	ENOG4105D0M	Protease HtpX homolog
AA314_08601	ENOG4107U9T	Pfam:Ribonuclease_BN
AA314_08603	ENOG4106UX7	integral membrane protein
AA314_08605	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
AA314_08606	ENOG4108WBT	adenosyltransferase
AA314_08607	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
AA314_08608	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
AA314_08613	ENOG4108JMX	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
AA314_08614	ENOG4105DCI	Phosphohydrolase
AA314_08615	ENOG4105CPF	Cell wall formation (By similarity)
AA314_08619	ENOG4105C7Z	Conserved Protein
AA314_08625	ENOG4108I7H	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AA314_08631	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AA314_08633	ENOG4105F8J	Adenylate Guanylate cyclase
AA314_08634	ENOG4105CSR	polyphosphate kinase 2
AA314_08635	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
AA314_08648	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
AA314_08656	ENOG4107TTQ	Alpha beta hydrolase fold
AA314_08658	ENOG4108SPH	protein kinase (EC 2.7.11.1)
AA314_08668	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
AA314_08669	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
AA314_08674	ENOG4105KNA	-acetyltransferase
AA314_08676	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
AA314_08679	ENOG4105CTD	carboxy-peptidase
AA314_08682	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
AA314_08683	ENOG4105EYW	Ion transport protein
AA314_08687	ENOG4105CJ1	ABC, transporter
AA314_08691	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
AA314_08692	ENOG4105WH1	Two component transcriptional regulator luxr family
AA314_08695	ENOG4105BZU	Histidine kinase
AA314_08696	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
AA314_08699	ENOG41083MR	nifu domain-containing protein
AA314_08703	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
AA314_08705	ENOG4108NVR	Methyl-accepting chemotaxis
AA314_08706	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
AA314_08707	ENOG4105CBS	Chea signal transduction histidine kinase
AA314_08709	ENOG4105BZU	Histidine kinase
AA314_08710	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
AA314_08711	ENOG4108Q9V	regulatoR
AA314_08712	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
AA314_08713	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
AA314_08714	ENOG4105C7S	Dehydrogenase
AA314_08715	ENOG4105VEQ	Cold shock protein
AA314_08718	ENOG4108NVR	Methyl-accepting chemotaxis
AA314_08720	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
AA314_08723	ENOG4105E5G	Alpha beta hydrolase fold
AA314_08732	ENOG4105IK6	Terpene synthase metal-binding domain-containing protein
AA314_08737	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
AA314_08739	ENOG4105D9P	serine threonine protein kinase
AA314_08740	ENOG4105D05	Receptor
AA314_08742	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AA314_08743	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
AA314_08744	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
AA314_08749	ENOG4108I0Q	anthranilate phosphoribosyltransferase
AA314_08750	ENOG4105DK0	Indole-3-glycerol phosphate synthase
AA314_08751	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
AA314_08752	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
AA314_08753	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
AA314_08756	ENOG4108ZM9	phosphoglycerate mutase
AA314_08757	ENOG4106A3M	Cytochrome p-450
AA314_08765	ENOG4105CRQ	synthase (Component I)
AA314_08767	ENOG4108Z0Z	intracellular protease Pfpi family
AA314_08769	ENOG4108RRZ	Transcription elongation factor GreB
AA314_08771	ENOG4108IXY	short-chain dehydrogenase reductase
AA314_08774	ENOG4107SFQ	iron-sulfur binding
AA314_08781	ENOG4105Z4T	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
AA314_08782	ENOG4105BZ9	Cytochrome C oxidase, subunit I
AA314_08802	ENOG4105C4R	Atp-dependent dna helicase
AA314_08803	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
AA314_08806	ENOG4108SPH	protein kinase (EC 2.7.11.1)
AA314_08807	ENOG4105BZU	Histidine kinase
AA314_08809	ENOG4108ZHJ	Organic hydroperoxide resistance protein
AA314_08810	ENOG4105DEN	Luciferase family
AA314_08811	ENOG4105K56	Transcriptional regulator
AA314_08812	ENOG4105EUB	pirin domain protein
AA314_08819	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
AA314_08821	ENOG4107RGC	Glycosyl transferase, family 2
AA314_08825	ENOG4105C0H	protease
AA314_08836	ENOG4108ESY	Metal dependent phosphohydrolase
AA314_08837	ENOG4105CA9	Pyruvate kinase
AA314_08840	ENOG4105F23	Fibronectin-binding protein
AA314_08842	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
AA314_08845	ENOG4105WH9	RNA polymerase
AA314_08849	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AA314_08850	ENOG4105CMQ	Chloride channel
AA314_08858	ENOG4105NVB	glycoside hydrolase, family 19
AA314_08863	ENOG4105D9P	serine threonine protein kinase
AA314_08870	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
AA314_08875	ENOG410901P	UPF0249 protein
AA314_08876	ENOG4105C0D	helicase
AA314_08880	ENOG4107R72	Ceramidase
AA314_08884	ENOG4105CBC	glutamate synthase
AA314_08885	ENOG4105BZU	Histidine kinase
AA314_08886	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
AA314_08888	ENOG4105D9P	serine threonine protein kinase
AA314_08890	ENOG4105DZQ	phospholipase D Transphosphatidylase
AA314_08891	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AA314_08895	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
AA314_08896	ENOG4105C9X	ppx gppa phosphatase
AA314_08901	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
AA314_08905	ENOG4108QJJ	Protein of unknown function (DUF1175)
AA314_08906	ENOG4107S52	alpha-2-macroglobulin domain protein
AA314_08907	ENOG4105EDV	vault protein
AA314_08908	ENOG4105JFG	SpoIID LytB domain protein
AA314_08915	ENOG4107URF	beta-phospho-glucomutase
AA314_08917	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
AA314_08919	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
AA314_08922	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
AA314_08924	ENOG4107ZQN	disulfide bond
AA314_08926	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
AA314_08928	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
AA314_08929	ENOG4108RXX	maleylacetoacetate isomerase
AA314_08935	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AA314_08936	ENOG4105BZU	Histidine kinase
AA314_08938	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
AA314_08939	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AA314_08940	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AA314_08962	ENOG4108JQ1	Dehydrogenase
AA314_08964	ENOG4105CQB	FAD linked oxidase domain protein
AA314_08983	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
AA314_08984	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
AA314_08985	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
AA314_08990	ENOG4105DA5	(ABC) transporter
AA314_08994	ENOG4105E4C	Lytic transglycosylase catalytic
AA314_08996	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
AA314_08998	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
AA314_09002	ENOG4105DSB	aldose 1-epimerase
AA314_09005	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
AA314_09012	ENOG4108V5V	Serine Threonine protein kinase
AA314_09016	ENOG4105ES5	Histidine kinase
AA314_09020	ENOG4105CPK	Glycosyl transferase (Group 1
AA314_09026	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
AA314_09027	ENOG4105CAS	nag kinase
AA314_09029	ENOG4105CAS	nag kinase
AA314_09030	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
AA314_09031	ENOG41080E2	ribosomal-protein-alanine acetyltransferase
AA314_09033	ENOG4108FN7	Aldo keto reductase
AA314_09036	ENOG4105CSM	endonuclease III
AA314_09039	ENOG4105ERG	peptidase m48, ste24p
AA314_09042	ENOG4107RRE	RNA-directed DNA polymerase
AA314_09047	ENOG4105CFG	Acts as a chaperone (By similarity)
AA314_09050	ENOG4108IQE	Amp-dependent synthetase and ligase
AA314_09055	ENOG4105CGH	5'-nucleotidase
AA314_09058	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
AA314_09070	ENOG4105C9Q	fumarate hydratase class II
AA314_09075	ENOG4107QP3	malate synthase g
AA314_09078	ENOG4106D4I	domain protein
AA314_09079	ENOG4107VRP	DNA repair exonuclease
AA314_09082	ENOG41087PP	glycosyltransferase MGT family
AA314_09083	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
AA314_09085	ENOG4108VCA	G U mismatch-specific DNA glycosylase
AA314_09093	ENOG4107SDU	Methyl-accepting chemotaxis
AA314_09096	ENOG4108QEV	ribosomal RNA large subunit methyltransferase N
AA314_09099	ENOG4108VX5	3-methyladenine DNA glycosylase
AA314_09103	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AA314_09111	ENOG4106A3M	Cytochrome p-450
AA314_09125	ENOG4105CJ1	ABC, transporter
AA314_09127	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
AA314_09132	ENOG4105C27	TonB-dependent Receptor Plug
AA314_09135	ENOG4105CFG	Acts as a chaperone (By similarity)
AA314_09139	ENOG4107QPV	Serine Threonine protein kinase
AA314_09143	ENOG4105E02	MotA TolQ exbB proton channel
AA314_09144	ENOG4105SG9	biopolymer transport protein, ExbD
AA314_09159	ENOG4105BZU	Histidine kinase
AA314_09170	ENOG4108ZG0	Ompa motb domain protein
AA314_09171	ENOG4105DIH	basic membrane
AA314_09172	ENOG4105DKQ	ROK family
AA314_09173	ENOG4108YYH	Nadph-dependent fmn reductase
AA314_09183	ENOG4107QPV	Serine Threonine protein kinase
AA314_09188	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
AA314_09189	ENOG4107QPV	Serine Threonine protein kinase
AA314_09193	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AA314_09195	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
AA314_09196	ENOG4105K5B	UPF0225 protein
AA314_09199	ENOG4108KPZ	tonB-dependent Receptor
AA314_09208	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
AA314_09209	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
AA314_09214	ENOG4105CMG	Carbohydrate kinase
AA314_09215	ENOG4105CVK	Glutamate decarboxylase
AA314_09217	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AA314_09220	ENOG4107QXV	Phosphate transporter
AA314_09225	ENOG4105KT7	mgtC SapB transporter
AA314_09226	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
AA314_09228	ENOG4105F3R	pts system mannose fructose sorbose family iid
AA314_09230	ENOG4108UZY	PTS System
AA314_09231	ENOG4105YHU	PTS system
AA314_09232	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
AA314_09233	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
AA314_09235	ENOG4105K59	histidine triad (HIT) protein
AA314_09240	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
AA314_09241	ENOG4106PBJ	Serine threonine-protein kinase Pkn6
AA314_09243	ENOG4105DQV	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity)
AA314_09250	ENOG4105EHG	Permease protein
AA314_09251	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
AA314_09257	ENOG4105KQC	Competence protein
AA314_09258	ENOG4106PBJ	Serine threonine-protein kinase Pkn6
AA314_09260	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
AA314_09262	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
AA314_09263	ENOG4108I5D	sulfate abc transporter
AA314_09264	ENOG4105ECW	sulfate abc transporter
AA314_09265	ENOG4108IJ6	ABC transporter
AA314_09266	ENOG4105VCH	membrane
AA314_09267	ENOG4108V8F	Transcriptional regulator, MarR family
AA314_09271	ENOG4106A3M	Cytochrome p-450
AA314_09272	ENOG4105EXC	Acyl-transferase
AA314_09273	ENOG4105CBG	Sulfatase
AA314_09276	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
AA314_09277	ENOG4105C6T	cysteine synthase
AA314_09282	ENOG4105BZU	Histidine kinase
AA314_09286	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
AA314_09289	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
AA314_09292	ENOG4105D17	glycoside hydrolase, family 3 domain protein
AA314_09296	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AA314_09299	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
AA314_09304	ENOG4108NVR	Methyl-accepting chemotaxis
AA314_09306	ENOG41065KQ	synthase
AA314_09317	ENOG4107RCI	amp-dependent synthetase and ligase
AA314_09331	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AA314_09333	ENOG4107B2H	carbonic anhydrase
AA314_09336	ENOG41068KF	Universal stress protein
AA314_09346	ENOG4106A3M	Cytochrome p-450
AA314_09347	ENOG4105BZP	glycoside hydrolase 15-related
AA314_09351	ENOG4105BZU	Histidine kinase
AA314_09352	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
AA314_09361	ENOG4107QZ7	Cellulose synthase catalytic subunit
AA314_09369	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
AA314_09374	ENOG4105F8J	Adenylate Guanylate cyclase
AA314_09375	ENOG4105F8J	Adenylate Guanylate cyclase
AA314_09380	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
AA314_09384	ENOG4108IV0	ABC, transporter
AA314_09385	ENOG4105C0Z	ABC transporter
AA314_09386	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
AA314_09387	ENOG4105C32	Amino acid ABC transporter (Permease)
AA314_09390	ENOG4108SPH	protein kinase (EC 2.7.11.1)
AA314_09391	ENOG4105CFG	Acts as a chaperone (By similarity)
AA314_09392	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AA314_09402	ENOG4105DTQ	mandelate racemase muconate lactonizing
AA314_09408	ENOG4105C8M	UPF0272 protein
AA314_09409	ENOG4105DTC	1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (air) carboxylase
AA314_09411	ENOG4105CG3	alpha amylase, catalytic region
AA314_09415	ENOG4105EG2	ABC transporter, permease
AA314_09417	ENOG4107FKK	extracellular solute-binding protein family 1
AA314_09418	ENOG4108IJ9	(ABC) transporter
AA314_09423	ENOG4105CBS	Chea signal transduction histidine kinase
AA314_09424	ENOG4107YTP	response regulator receiver protein
AA314_09425	ENOG410807Z	Modulation of CheA activity in response to attractants (Chemotaxis
AA314_09426	ENOG4107SDU	Methyl-accepting chemotaxis
AA314_09427	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
AA314_09430	ENOG4105BZU	Histidine kinase
AA314_09431	ENOG4105CXV	gliding motility protein
AA314_09433	ENOG4105CZX	twitching motility protein
AA314_09434	ENOG4105CZX	twitching motility protein
AA314_09436	ENOG4105DVT	helicase
AA314_09439	ENOG4108UYB	regulatoR
AA314_09445	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
AA314_09448	ENOG4107TE5	Lipid kinase
AA314_09449	ENOG4105DZP	Membrane-associated zinc metalloprotease
AA314_09450	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
AA314_09454	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
AA314_09459	ENOG4105FDR	Membrane
AA314_09460	ENOG4105C5F	glutamine synthetase
AA314_09470	ENOG4105EYW	Ion transport protein
AA314_09475	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
AA314_09482	ENOG4105EMN	RNA polymerase sigma factor
AA314_09485	ENOG4105E0A	ABC, transporter
AA314_09486	ENOG410814C	multidrug resistance protein
AA314_09489	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
AA314_09493	ENOG4105BZU	Histidine kinase
AA314_09499	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
AA314_09503	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
AA314_09504	ENOG4105KZX	Pterin carbinolamine dehydratase
AA314_09511	ENOG4105CWC	Acetylornithine deacetylase
AA314_09512	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
AA314_09513	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
AA314_09518	ENOG4105DY8	decarboxylase
AA314_09522	ENOG4105DFF	Rod shape-determining protein mreb
AA314_09526	ENOG4105C19	ABC transporter
AA314_09536	ENOG41090B9	response to stress
AA314_09539	ENOG4105CD8	aminopeptidase N
AA314_09544	ENOG4106PBJ	Serine threonine-protein kinase Pkn6
AA314_09553	ENOG4105BZ1	(ABC) transporter
AA314_09557	ENOG4108SDH	ABC, transporter
AA314_09558	ENOG4108IUW	ABC transporter
AA314_09561	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
AA314_09565	ENOG4108JUA	Transcriptional regulator
AA314_09576	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
AA314_09577	ENOG41080RH	Thioredoxin
AA314_09578	ENOG4108V1T	peptidylprolyl cis-trans isomerase
AA314_09582	ENOG4105C4K	Nad synthetase
AA314_09583	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
AA314_09587	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
AA314_09593	ENOG4105BZU	Histidine kinase
AA314_09597	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
AA314_09601	ENOG4108W5X	Transcriptional Regulator, LuxR family
AA314_09606	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AA314_09609	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
AA314_09612	ENOG4105UYK	outer membrane protein a
AA314_09620	ENOG4108KPZ	tonB-dependent Receptor
AA314_09623	ENOG4105BZU	Histidine kinase
AA314_09624	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AA314_09627	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
AA314_09628	ENOG4105BZU	Histidine kinase
AA314_09629	ENOG4105C8Q	Methyl-accepting chemotaxis
AA314_09630	ENOG4108V3W	Chemotaxis protein, CheW
AA314_09631	ENOG4105C8Q	Methyl-accepting chemotaxis
AA314_09632	ENOG4105CBS	Chea signal transduction histidine kinase
AA314_09633	ENOG4108V3W	Chemotaxis protein, CheW
AA314_09634	ENOG4105C8Q	Methyl-accepting chemotaxis
AA314_09635	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AA314_09636	ENOG4105BZU	Histidine kinase
AA314_09641	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
AA314_09643	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
AA314_09646	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
AA314_09653	ENOG4107RCI	amp-dependent synthetase and ligase
AA314_09660	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
AA314_09662	ENOG4105K59	histidine triad (HIT) protein
AA314_09664	ENOG4108IQE	Amp-dependent synthetase and ligase
AA314_09670	ENOG4105E6M	Sulphatase-modifying factor protein
AA314_09672	ENOG4105D9P	serine threonine protein kinase
AA314_09677	ENOG41065RQ	ADP-ribosylation crystallin J1
AA314_09679	ENOG4105KPV	Transcriptional regulator
AA314_09680	ENOG4107QK7	reductase
AA314_09682	ENOG41082MC	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
AA314_09684	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
AA314_09685	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
AA314_09688	ENOG4108UB4	uncharacterized protein ygjQ
AA314_09694	ENOG4105K63	Thioredoxin
AA314_09696	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
AA314_09698	ENOG4105DGW	oligopeptidase A
AA314_09705	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
AA314_09706	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
AA314_09708	ENOG4105CP2	von willebrand factor, type a
AA314_09713	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
AA314_09720	ENOG4105BZU	Histidine kinase
AA314_09721	ENOG4105CGZ	zinc metallopeptidase
AA314_09722	ENOG4105E09	nadh pyrophosphatase
AA314_09723	ENOG4105D5Q	Arginine ornithine antiporter
AA314_09735	ENOG4105EWK	phytoene
AA314_09736	ENOG4105BZU	Histidine kinase
AA314_09739	ENOG4105BZU	Histidine kinase
AA314_09740	ENOG4105YFD	chemotaxis, protein
AA314_09741	ENOG4105BZU	Histidine kinase
AA314_09744	ENOG4107WTJ	Methyl-accepting chemotaxis sensory transducer
AA314_09745	ENOG4105CBS	Chea signal transduction histidine kinase
AA314_09746	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
AA314_09747	ENOG4105BZU	Histidine kinase
AA314_09752	ENOG4105BZU	Histidine kinase
AA314_09753	ENOG4108V3W	Chemotaxis protein, CheW
AA314_09754	ENOG4105C8Q	Methyl-accepting chemotaxis
AA314_09755	ENOG4105C8Q	Methyl-accepting chemotaxis
AA314_09756	ENOG4105CBS	Chea signal transduction histidine kinase
AA314_09757	ENOG4105CBS	Chea signal transduction histidine kinase
AA314_09759	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
AA314_09761	ENOG4105VF7	tolerance protein
AA314_09765	ENOG4105DU1	integral membrane protein, terc
AA314_09775	ENOG4105BZU	Histidine kinase
AA314_09776	ENOG4105DNE	Transposase
AA314_09779	ENOG4105BZU	Histidine kinase
AA314_09792	ENOG4107QI1	Mate efflux family protein
AA314_09796	ENOG4106PBJ	Serine threonine-protein kinase Pkn6
AA314_09800	ENOG4105CFG	Acts as a chaperone (By similarity)
AA314_09801	ENOG4105E3N	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
AA314_09802	ENOG410804D	Sensor Signal Transduction Histidine Kinase
AA314_09803	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
AA314_09808	ENOG4105BZU	Histidine kinase
AA314_09809	ENOG41065SU	Two-component system sensor kinase
AA314_09811	ENOG4107Z3H	Transcriptional regulator, TetR family
AA314_09818	ENOG4105CPT	Alpha beta hydrolase
AA314_09824	ENOG4105ISI	outer membrane protein, OMPP1 FadL TodX family
AA314_09825	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
AA314_09826	ENOG4105CN1	protease
AA314_09831	ENOG4107QVI	Methyltransferase, type 11
AA314_09840	ENOG4108X7A	Terpene synthase metal-binding domain-containing protein
AA314_09848	ENOG4105CIF	Ornithine Cyclodeaminase
AA314_09849	ENOG4105BZU	Histidine kinase
AA314_09851	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
AA314_09882	ENOG4105BZU	Histidine kinase
AA314_09892	ENOG41068KG	domain protein
AA314_09893	ENOG4105CXV	gliding motility protein
AA314_09894	ENOG4105CSU	acyl-Coa dehydrogenase
AA314_09897	ENOG4105CHR	reductase
AA314_09899	ENOG4105ETT	transcriptional Regulator, LysR family
AA314_09901	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
AA314_09903	ENOG4108SQ4	Glyoxalase Bleomycin resistance protein (Dioxygenase
AA314_09904	ENOG4108903	Formimidoylglutamase
AA314_09909	ENOG4108V1T	peptidylprolyl cis-trans isomerase
AA314_09910	ENOG4105BZU	Histidine kinase
AA314_09911	ENOG4105BZU	Histidine kinase
AA314_09912	ENOG4105BZU	Histidine kinase
AA314_09920	ENOG4105BZU	Histidine kinase
AA314_09921	ENOG4105CUX	Signal transduction histidine kinase
AA314_09923	ENOG4105CSH	Transporter
AA314_09937	ENOG4107TH8	cina domain protein
AA314_09940	ENOG4105CEY	Amp-dependent synthetase and ligase
AA314_09941	ENOG4105EHU	Circadian clock protein KaiC
AA314_09944	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
AA314_09947	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
AA314_09951	ENOG4105E39	Enoyl-CoA hydratase
AA314_09954	ENOG4105D1S	lipid A biosynthesis
AA314_09955	ENOG4107S1Q	Phosphatase
AA314_09957	ENOG4105K63	Thioredoxin
AA314_09960	ENOG4105D44	asparaginase
AA314_09968	ENOG4107QPV	Serine Threonine protein kinase
AA314_09970	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AA314_09973	ENOG4107YZX	Universal stress protein
AA314_09977	ENOG4105BZU	Histidine kinase
AA314_09994	ENOG4105MPN	Membrane
AA314_09997	ENOG4105CQZ	Histidine kinase
AA314_09998	ENOG4105CZN	Potassium uptake protein
AA314_10004	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
AA314_10009	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
AA314_10015	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
AA314_10017	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
AA314_10019	ENOG4107QHF	type ii secretion system protein e
AA314_10021	ENOG4105CA0	peroxidase
AA314_10023	ENOG4107ZYJ	bioY protein
AA314_10024	ENOG4107QCX	Transporter
AA314_10025	ENOG4108JJB	ABC transporter
AA314_10026	ENOG4105CEP	NADH dehydrogenase
AA314_10035	ENOG4105CYM	Glutathione S-transferase
AA314_10036	ENOG4105DV0	amidase (EC 3.5.1.4
AA314_10045	ENOG4105CVW	peptidase s1 and s6 chymotrypsin hap
AA314_10050	ENOG4107E2E	PKHD-type hydroxylase
AA314_10053	ENOG4108ESX	Receptor
AA314_10058	ENOG4107QPV	Serine Threonine protein kinase
AA314_10060	ENOG4105D9P	serine threonine protein kinase
AA314_10062	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AA314_10063	ENOG4108K8S	endonuclease I
AA314_10071	ENOG4107T3P	ABC, transporter
AA314_10073	ENOG4105VEQ	Cold shock protein
AA314_10077	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AA314_10078	ENOG4105BZU	Histidine kinase
AA314_10084	ENOG4107SM8	Adenylate Guanylate cyclase
AA314_10091	ENOG4107SM8	Adenylate Guanylate cyclase
AA314_10092	ENOG4108VYJ	response regulator receiver protein
AA314_10096	ENOG4105BZU	Histidine kinase
AA314_10102	ENOG4108SC4	)-transporter
AA314_10104	ENOG4105CD5	CoA-binding domain protein
AA314_10108	ENOG4108HMN	Caspase domain
AA314_10110	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
AA314_10111	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
AA314_10112	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
AA314_10121	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family