locus-tag	class	description
JRI60_00005	COG0445	tRNA wobble uridine modification
JRI60_00010	COG0357	Ribosomal RNA small subunit methyltransferase G
JRI60_00020	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JRI60_00030	COG1192	Involved in chromosome partitioning
JRI60_00035	COG1475	DNA binding
JRI60_00055	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
JRI60_00060	COG1262	PFAM Formylglycine-generating sulfatase enzyme
JRI60_00065	COG0405	Gamma-glutamyltransferase
JRI60_00080	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
JRI60_00155	COG0701	Predicted permease
JRI60_00175	COG0437	4 iron, 4 sulfur cluster binding
JRI60_00210	COG1845	cytochrome c oxidase, subunit III
JRI60_00210	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JRI60_00255	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JRI60_00270	COG0625	glutathione transferase activity
JRI60_00345	COG1127	ABC transporter
JRI60_00445	COG1309	transcriptional regulator
JRI60_00450	COG4221	oxidoreductase activity
JRI60_00480	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JRI60_00535	COG0583	DNA-binding transcription factor activity
JRI60_00550	COG0583	DNA-binding transcription factor activity
JRI60_00555	COG0667	Aldo Keto reductase
JRI60_00560	COG0243	molybdopterin cofactor binding
JRI60_00590	COG3631	Ketosteroid isomerase-related protein
JRI60_00595	COG0702	epimerase
JRI60_00615	COG1793	dna ligase
JRI60_00630	COG5002	protein histidine kinase activity
JRI60_00655	COG3850	Histidine kinase
JRI60_00655	COG5002	protein histidine kinase activity
JRI60_00700	COG2226	methyltransferase
JRI60_00715	COG0519	Catalyzes the synthesis of GMP from XMP
JRI60_00720	COG0523	cobalamin synthesis protein
JRI60_00725	COG1301	dicarboxylic acid transport
JRI60_00755	COG1335	isochorismatase
JRI60_00835	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
JRI60_00840	COG4181	ATPase activity
JRI60_00855	COG0583	DNA-binding transcription factor activity
JRI60_00865	COG2764	glyoxalase bleomycin resistance protein dioxygenase
JRI60_00915	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
JRI60_00925	COG0625	glutathione transferase activity
JRI60_00930	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
JRI60_00970	COG1902	pentaerythritol trinitrate reductase activity
JRI60_00990	COG2223	nitrite transmembrane transporter activity
JRI60_00995	COG1349	DNA-binding transcription factor activity
JRI60_01000	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JRI60_01020	COG1472	Belongs to the glycosyl hydrolase 3 family
JRI60_01040	COG0667	Aldo Keto reductase
JRI60_01045	COG1733	regulation of RNA biosynthetic process
JRI60_01055	COG0753	catalase activity
JRI60_01075	COG1653	transport
JRI60_01135	COG3227	Zinc metalloprotease (Elastase)
JRI60_01170	COG0515	serine threonine protein kinase
JRI60_01170	COG2815	serine threonine protein kinase
JRI60_01185	COG3174	membrane
JRI60_01200	COG5464	transposase or invertase
JRI60_01235	COG0697	spore germination
JRI60_01265	COG0667	Aldo Keto reductase
JRI60_01270	COG3034	peptidoglycan biosynthetic process
JRI60_01275	COG0656	L-ascorbic acid biosynthetic process
JRI60_01280	COG3290	protein histidine kinase activity
JRI60_01280	COG0840	transmembrane signaling receptor activity
JRI60_01305	COG0657	acetylesterase activity
JRI60_01310	COG4774	siderophore transport
JRI60_01330	COG1819	glycosyl
JRI60_01335	COG0515	serine threonine protein kinase
JRI60_01380	COG2197	response regulator
JRI60_01400	COG2267	carboxylic ester hydrolase activity
JRI60_01415	COG0515	serine threonine protein kinase
JRI60_01415	COG2815	serine threonine protein kinase
JRI60_01425	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JRI60_01445	COG0515	serine threonine protein kinase
JRI60_01450	COG0423	glycine-tRNA ligase activity
JRI60_01460	COG1228	amidohydrolase
JRI60_01475	COG0483	inositol monophosphate 1-phosphatase activity
JRI60_01485	COG0714	Associated with various cellular activities
JRI60_01490	COG1569	PIN domain
JRI60_01495	COG3311	Transcriptional regulator
JRI60_01570	COG1024	Enoyl-CoA hydratase
JRI60_01580	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JRI60_01585	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JRI60_01610	COG0028	Belongs to the TPP enzyme family
JRI60_01630	COG5002	protein histidine kinase activity
JRI60_01635	COG2124	cytochrome p450
JRI60_01650	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JRI60_01655	COG2207	Transcriptional regulator
JRI60_01685	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
JRI60_01715	COG2124	cytochrome p450
JRI60_01735	COG1763	Mo-molybdopterin cofactor biosynthetic process
JRI60_01815	COG0277	FAD linked oxidase domain protein
JRI60_01830	COG2204	response regulator
JRI60_01855	COG0437	4 iron, 4 sulfur cluster binding
JRI60_01890	COG4221	oxidoreductase activity
JRI60_01900	COG1739	Uncharacterized protein family UPF0029
JRI60_01935	COG0506	proline dehydrogenase activity
JRI60_01940	COG2267	carboxylic ester hydrolase activity
JRI60_01960	COG3483	tryptophan 2,3-dioxygenase activity
JRI60_02000	COG0589	response to stress
JRI60_02015	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
JRI60_02025	COG5002	protein histidine kinase activity
JRI60_02025	COG0784	Response regulator, receiver
JRI60_02030	COG3179	chitinase
JRI60_02060	COG0516	GMP reductase activity
JRI60_02060	COG0517	IMP dehydrogenase activity
JRI60_02065	COG2124	cytochrome p450
JRI60_02070	COG0003	Pfam Anion-transporting ATPase
JRI60_02085	COG5002	protein histidine kinase activity
JRI60_02095	COG0235	Class ii aldolase
JRI60_02100	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
JRI60_02105	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
JRI60_02120	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JRI60_02150	COG1917	Cupin 2, conserved barrel domain protein
JRI60_02155	COG0583	DNA-binding transcription factor activity
JRI60_02170	COG2124	cytochrome p450
JRI60_02220	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JRI60_02250	COG2843	Capsule synthesis protein
JRI60_02275	COG2223	nitrite transmembrane transporter activity
JRI60_02290	COG0625	glutathione transferase activity
JRI60_02300	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
JRI60_02305	COG1984	allophanate hydrolase subunit 2
JRI60_02320	COG1940	carbohydrate kinase activity
JRI60_02325	COG4213	ABC transporter substrate-binding protein
JRI60_02360	COG4191	Histidine kinase
JRI60_02405	COG0328	RNA-DNA hybrid ribonuclease activity
JRI60_02415	COG2130	NADP-dependent
JRI60_02425	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JRI60_02425	COG2124	cytochrome p450
JRI60_02430	COG2124	cytochrome p450
JRI60_02440	COG0737	Belongs to the 5'-nucleotidase family
JRI60_02460	COG0596	Alpha beta hydrolase
JRI60_02465	COG3290	protein histidine kinase activity
JRI60_02475	COG0242	peptide deformylase activity
JRI60_02550	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
JRI60_02550	COG0493	'glutamate synthase
JRI60_02555	COG4221	oxidoreductase activity
JRI60_02560	COG0702	epimerase
JRI60_02620	COG0784	Response regulator, receiver
JRI60_02620	COG2205	protein histidine kinase activity
JRI60_02635	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
JRI60_02640	COG1404	Belongs to the peptidase S8 family
JRI60_02650	COG1595	DNA-templated transcription, initiation
JRI60_02665	COG0232	Belongs to the dGTPase family. Type 2 subfamily
JRI60_02700	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JRI60_02725	COG0456	acetyltransferase
JRI60_02725	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
JRI60_02735	COG2267	carboxylic ester hydrolase activity
JRI60_02740	COG1309	transcriptional regulator
JRI60_02805	COG2124	cytochrome p450
JRI60_02810	COG0243	molybdopterin cofactor binding
JRI60_02895	COG2855	membrane
JRI60_02920	COG1233	COG1233 Phytoene dehydrogenase and related
JRI60_02950	COG0784	Response regulator, receiver
JRI60_02955	COG1672	PFAM Archaeal ATPase
JRI60_02955	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
JRI60_02975	COG1672	PFAM Archaeal ATPase
JRI60_02975	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
JRI60_03010	COG1278	Cold shock
JRI60_03015	COG2205	protein histidine kinase activity
JRI60_03045	COG2204	response regulator
JRI60_03100	COG0702	epimerase
JRI60_03105	COG1733	regulation of RNA biosynthetic process
JRI60_03120	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
JRI60_03125	COG3852	Histidine kinase
JRI60_03155	COG1252	NADH dehydrogenase
JRI60_03160	COG1122	ATPase activity
JRI60_03165	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JRI60_03170	COG1268	BioY protein
JRI60_03175	COG1858	cytochrome C peroxidase
JRI60_03185	COG2201	protein-glutamate methylesterase activity
JRI60_03205	COG0653	protein targeting
JRI60_03275	COG1051	belongs to the nudix hydrolase family
JRI60_03275	COG1056	cytidyltransferase-related domain
JRI60_03305	COG2205	protein histidine kinase activity
JRI60_03315	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
JRI60_03320	COG0589	response to stress
JRI60_03345	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JRI60_03345	COG0515	serine threonine protein kinase
JRI60_03360	COG2234	aminopeptidase activity
JRI60_03425	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
JRI60_03430	COG3321	synthase
JRI60_03430	COG0604	alcohol dehydrogenase
JRI60_03435	COG1882	Formate acetyltransferase
JRI60_03445	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JRI60_03450	COG3321	synthase
JRI60_03450	COG4221	oxidoreductase activity
JRI60_03450	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JRI60_03450	COG0300	oxidoreductase activity
JRI60_03465	COG0318	PFAM AMP-dependent synthetase and ligase
JRI60_03475	COG2133	pyrroloquinoline quinone binding
JRI60_03485	COG1446	asparaginase
JRI60_03495	COG3118	belongs to the thioredoxin family
JRI60_03520	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
JRI60_03525	COG1560	Kdo2-lipid A biosynthetic process
JRI60_03540	COG1024	Enoyl-CoA hydratase
JRI60_03555	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JRI60_03580	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
JRI60_03590	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
JRI60_03595	COG0318	PFAM AMP-dependent synthetase and ligase
JRI60_03610	COG1058	Belongs to the CinA family
JRI60_03610	COG1546	Belongs to the CinA family
JRI60_03655	COG0477	Major facilitator Superfamily
JRI60_03660	COG3852	Histidine kinase
JRI60_03680	COG3268	Saccharopine dehydrogenase
JRI60_03685	COG0823	Involved in the tonB-independent uptake of proteins
JRI60_03750	COG2205	protein histidine kinase activity
JRI60_03750	COG0784	Response regulator, receiver
JRI60_03755	COG0545	Peptidyl-prolyl cis-trans isomerase
JRI60_03760	COG0412	Dienelactone hydrolase
JRI60_03770	COG0010	Belongs to the arginase family
JRI60_03775	COG0515	serine threonine protein kinase
JRI60_03855	COG0784	Response regulator, receiver
JRI60_03855	COG4191	Histidine kinase
JRI60_03870	COG5006	permease, DMT superfamily
JRI60_03910	COG0515	serine threonine protein kinase
JRI60_03940	COG5002	protein histidine kinase activity
JRI60_03945	COG0697	spore germination
JRI60_03950	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JRI60_04005	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JRI60_04085	COG0653	protein targeting
JRI60_04140	COG1309	transcriptional regulator
JRI60_04145	COG2202	Pas domain
JRI60_04145	COG2205	protein histidine kinase activity
JRI60_04175	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JRI60_04180	COG0443	Heat shock 70 kDa protein
JRI60_04255	COG0745	RESPONSE REGULATOR receiver
JRI60_04320	COG0542	response to heat
JRI60_04335	COG1324	tolerance protein
JRI60_04345	COG0745	RESPONSE REGULATOR receiver
JRI60_04355	COG0643	Histidine kinase
JRI60_04355	COG2198	Histidine kinase
JRI60_04365	COG0840	transmembrane signaling receptor activity
JRI60_04370	COG0835	chemotaxis
JRI60_04390	COG2723	6-phospho-beta-galactosidase activity
JRI60_04415	COG5002	protein histidine kinase activity
JRI60_04420	COG2201	protein-glutamate methylesterase activity
JRI60_04430	COG0840	transmembrane signaling receptor activity
JRI60_04445	COG0835	chemotaxis
JRI60_04470	COG2124	cytochrome p450
JRI60_04495	COG4989	oxidoreductase activity
JRI60_04515	COG2066	Belongs to the glutaminase family
JRI60_04515	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
JRI60_04600	COG0588	phosphoglycerate mutase activity
JRI60_04625	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JRI60_04630	COG0135	phosphoribosylanthranilate isomerase activity
JRI60_04635	COG0339	signal peptide processing
JRI60_04650	COG3118	belongs to the thioredoxin family
JRI60_04670	COG0628	permease
JRI60_04680	COG2949	membrane
JRI60_04690	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
JRI60_04695	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
JRI60_04705	COG0355	proton-transporting ATP synthase activity, rotational mechanism
JRI60_04710	COG2346	COG2346, Truncated hemoglobins
JRI60_04720	COG1959	2 iron, 2 sulfur cluster binding
JRI60_04745	COG1271	oxidase subunit
JRI60_04755	COG1022	Amp-dependent synthetase and ligase
JRI60_04760	COG4251	negative regulation of phosphorylation
JRI60_04765	COG5002	protein histidine kinase activity
JRI60_04770	COG1505	serine-type exopeptidase activity
JRI60_04775	COG0537	adenosine 5'-monophosphoramidase activity
JRI60_04785	COG1228	amidohydrolase
JRI60_04790	COG0739	heme binding
JRI60_04810	COG0515	serine threonine protein kinase
JRI60_04810	COG2815	serine threonine protein kinase
JRI60_04815	COG2815	serine threonine protein kinase
JRI60_04815	COG0515	serine threonine protein kinase
JRI60_04840	COG0515	serine threonine protein kinase
JRI60_04840	COG2815	serine threonine protein kinase
JRI60_04845	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JRI60_04880	COG3852	Histidine kinase
JRI60_04905	COG0835	chemotaxis
JRI60_04915	COG2201	protein-glutamate methylesterase activity
JRI60_04945	COG5002	protein histidine kinase activity
JRI60_05010	COG2204	response regulator
JRI60_05070	COG2205	protein histidine kinase activity
JRI60_05075	COG3852	Histidine kinase
JRI60_05100	COG0546	phosphoglycolate phosphatase activity
JRI60_05110	COG4191	Histidine kinase
JRI60_05125	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
JRI60_05125	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JRI60_05140	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JRI60_05145	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JRI60_05150	COG3781	membrane
JRI60_05165	COG2204	response regulator
JRI60_05185	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
JRI60_05200	COG4555	ABC transporter
JRI60_05205	COG1668	transmembrane transport
JRI60_05240	COG0308	aminopeptidase N
JRI60_05285	COG0625	glutathione transferase activity
JRI60_05290	COG0583	DNA-binding transcription factor activity
JRI60_05320	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JRI60_05350	COG1673	EVE domain
JRI60_05355	COG2378	regulation of single-species biofilm formation
JRI60_05375	COG2066	Belongs to the glutaminase family
JRI60_05380	COG2433	Pfam Transposase IS66
JRI60_05405	COG3321	synthase
JRI60_05405	COG0604	alcohol dehydrogenase
JRI60_05415	COG0667	Aldo Keto reductase
JRI60_05420	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JRI60_05430	COG0667	Aldo Keto reductase
JRI60_05450	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
JRI60_05480	COG0515	serine threonine protein kinase
JRI60_05480	COG2815	serine threonine protein kinase
JRI60_05485	COG4977	sequence-specific DNA binding
JRI60_05495	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JRI60_05505	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JRI60_05550	COG1846	Transcriptional regulator
JRI60_05570	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JRI60_05575	COG1136	(ABC) transporter
JRI60_05585	COG1136	(ABC) transporter
JRI60_05585	COG0577	efflux transmembrane transporter activity
JRI60_05590	COG1077	Cell shape determining protein MreB Mrl
JRI60_05600	COG0463	Glycosyl transferase, family 2
JRI60_05610	COG3239	Fatty acid desaturase
JRI60_05615	COG0076	glutamate decarboxylase activity
JRI60_05630	COG2171	N-acyltransferase activity
JRI60_05635	COG1672	PFAM Archaeal ATPase
JRI60_05635	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
JRI60_05640	COG2205	protein histidine kinase activity
JRI60_05645	COG2264	protein methyltransferase activity
JRI60_05650	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JRI60_05670	COG2154	pterin-4-alpha-carbinolamine dehydratase
JRI60_05675	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JRI60_05685	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JRI60_05705	COG0577	efflux transmembrane transporter activity
JRI60_05715	COG5002	protein histidine kinase activity
JRI60_05740	COG0408	coproporphyrinogen oxidase activity
JRI60_05790	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
JRI60_05790	COG4651	solute:proton antiporter activity
JRI60_05795	COG0534	Mate efflux family protein
JRI60_05805	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JRI60_05810	COG0025	NhaP-type Na H and K H
JRI60_05820	COG2133	pyrroloquinoline quinone binding
JRI60_05845	COG1744	ABC transporter substrate-binding protein PnrA-like
JRI60_05865	COG0697	spore germination
JRI60_05870	COG1420	regulation of RNA biosynthetic process
JRI60_05880	COG1597	lipid kinase activity
JRI60_05885	COG0546	phosphoglycolate phosphatase activity
JRI60_05915	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
JRI60_05920	COG2271	Major facilitator Superfamily
JRI60_05925	COG1199	ATP-dependent helicase activity
JRI60_05945	COG1100	Small GTP-binding protein
JRI60_05950	COG2198	Histidine kinase
JRI60_05950	COG5002	protein histidine kinase activity
JRI60_05950	COG0784	Response regulator, receiver
JRI60_05955	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
JRI60_05960	COG0840	transmembrane signaling receptor activity
JRI60_05965	COG0835	chemotaxis
JRI60_05970	COG2201	protein-glutamate methylesterase activity
JRI60_05975	COG2198	Histidine kinase
JRI60_05975	COG0643	Histidine kinase
JRI60_05995	COG3842	ATPase activity
JRI60_06010	COG3833	ABC-type maltose transport systems, permease component
JRI60_06030	COG0366	Alpha amylase catalytic
JRI60_06040	COG1691	(AIR) carboxylase
JRI60_06045	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
JRI60_06090	COG4948	Mandelate Racemase Muconate Lactonizing
JRI60_06130	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JRI60_06135	COG0443	Heat shock 70 kDa protein
JRI60_06140	COG0515	serine threonine protein kinase
JRI60_06200	COG4106	trans-aconitate 2-methyltransferase activity
JRI60_06225	COG1404	Belongs to the peptidase S8 family
JRI60_06235	COG0442	prolyl-tRNA aminoacylation
JRI60_06260	COG4969	Belongs to the N-Me-Phe pilin family
JRI60_06290	COG1846	Transcriptional regulator
JRI60_06325	COG1755	Isoprenylcysteine carboxyl methyltransferase
JRI60_06335	COG0318	PFAM AMP-dependent synthetase and ligase
JRI60_06365	COG0318	PFAM AMP-dependent synthetase and ligase
JRI60_06370	COG3424	synthase
JRI60_06385	COG0277	FAD linked oxidase domain protein
JRI60_06400	COG0745	RESPONSE REGULATOR receiver
JRI60_06415	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JRI60_06435	COG1472	Belongs to the glycosyl hydrolase 3 family
JRI60_06450	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JRI60_06515	COG0714	Associated with various cellular activities
JRI60_06525	COG0443	Heat shock 70 kDa protein
JRI60_06530	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
JRI60_06530	COG0475	glutathione-regulated potassium exporter activity
JRI60_06555	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JRI60_06565	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JRI60_06590	COG1846	Transcriptional regulator
JRI60_06600	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
JRI60_06605	COG4208	sulfate ABC transporter
JRI60_06610	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
JRI60_06620	COG0406	alpha-ribazole phosphatase activity
JRI60_06635	COG1596	polysaccharide export
JRI60_06635	COG1555	photosystem II stabilization
JRI60_06665	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JRI60_06705	COG0723	plastoquinol--plastocyanin reductase activity
JRI60_06715	COG0515	serine threonine protein kinase
JRI60_06720	COG1120	ATPase activity
JRI60_06735	COG0537	adenosine 5'-monophosphoramidase activity
JRI60_06745	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
JRI60_06750	COG1660	Displays ATPase and GTPase activities
JRI60_06755	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
JRI60_06755	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JRI60_06760	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JRI60_06770	COG3716	PTS system mannose fructose sorbose family IID component
JRI60_06780	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JRI60_06785	COG1285	pathogenesis
JRI60_06795	COG0306	phosphate transporter
JRI60_06810	COG1070	Carbohydrate kinase
JRI60_06815	COG0829	nickel cation binding
JRI60_06820	COG0831	urea catabolic process
JRI60_06820	COG0832	Belongs to the urease beta subunit family
JRI60_06825	COG0804	urea catabolic process
JRI60_06835	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
JRI60_06855	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JRI60_06860	COG0402	S-adenosylhomocysteine deaminase activity
JRI60_06885	COG1022	Amp-dependent synthetase and ligase
JRI60_06910	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JRI60_06915	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
JRI60_06975	COG3012	SEC-C Motif Domain Protein
JRI60_06980	COG1968	undecaprenyl-diphosphatase activity
JRI60_06990	COG2204	response regulator
JRI60_06995	COG4191	Histidine kinase
JRI60_07055	COG1940	carbohydrate kinase activity
JRI60_07060	COG1744	ABC transporter substrate-binding protein PnrA-like
JRI60_07075	COG3437	response regulator, receiver
JRI60_07075	COG2205	protein histidine kinase activity
JRI60_07075	COG3850	Histidine kinase
JRI60_07075	COG4999	Histidine kinase
JRI60_07090	COG2124	cytochrome p450
JRI60_07130	COG0656	L-ascorbic acid biosynthetic process
JRI60_07170	COG0515	serine threonine protein kinase
JRI60_07170	COG2815	serine threonine protein kinase
JRI60_07195	COG4771	TonB-dependent receptor
JRI60_07215	COG0714	Associated with various cellular activities
JRI60_07225	COG1131	(ABC) transporter
JRI60_07305	COG2124	cytochrome p450
JRI60_07310	COG2204	response regulator
JRI60_07330	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
JRI60_07335	COG0730	response to heat
JRI60_07365	COG1640	4-alpha-glucanotransferase
JRI60_07370	COG2094	Belongs to the DNA glycosylase MPG family
JRI60_07385	COG0820	rRNA (adenine-C2-)-methyltransferase activity
JRI60_07435	COG3663	DNA glycosylase
JRI60_07455	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JRI60_07465	COG0477	Major facilitator Superfamily
JRI60_07475	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
JRI60_07505	COG0318	PFAM AMP-dependent synthetase and ligase
JRI60_07515	COG0420	3'-5' exonuclease activity
JRI60_07520	COG4717	serine-type aminopeptidase activity
JRI60_07525	COG2224	Isocitrate lyase
JRI60_07530	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
JRI60_07550	COG0114	fumarate hydratase activity
JRI60_07575	COG0740	serine-type endopeptidase activity
JRI60_07590	COG0737	Belongs to the 5'-nucleotidase family
JRI60_07620	COG1022	Amp-dependent synthetase and ligase
JRI60_07650	COG1397	ADP-ribosylglycohydrolase
JRI60_07670	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JRI60_07720	COG0456	acetyltransferase
JRI60_07725	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
JRI60_07730	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
JRI60_07745	COG4191	Histidine kinase
JRI60_07765	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
JRI60_07765	COG2755	lipolytic protein G-D-S-L family
JRI60_07795	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
JRI60_07810	COG0676	glucose-6-phosphate 1-epimerase activity
JRI60_07815	COG3608	succinylglutamate desuccinylase aspartoacylase
JRI60_07815	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
JRI60_07880	COG3158	transport of potassium into the cell
JRI60_07940	COG0574	Belongs to the PEP-utilizing enzyme family
JRI60_07940	COG3848	Pyruvate phosphate dikinase
JRI60_08080	COG0515	serine threonine protein kinase
JRI60_08115	COG3142	Participates in the control of copper homeostasis
JRI60_08125	COG2124	cytochrome p450
JRI60_08135	COG0741	lytic transglycosylase activity
JRI60_08165	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
JRI60_08270	COG0277	FAD linked oxidase domain protein
JRI60_08280	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JRI60_08320	COG3942	CHAP domain
JRI60_08320	COG1388	LysM domain
JRI60_08370	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_08390	COG0577	efflux transmembrane transporter activity
JRI60_08390	COG1136	(ABC) transporter
JRI60_08395	COG1136	(ABC) transporter
JRI60_08395	COG0577	efflux transmembrane transporter activity
JRI60_08400	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JRI60_08410	COG0745	RESPONSE REGULATOR receiver
JRI60_08430	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
JRI60_08450	COG5002	protein histidine kinase activity
JRI60_08455	COG0745	RESPONSE REGULATOR receiver
JRI60_08485	COG0625	glutathione transferase activity
JRI60_08490	COG3185	4-Hydroxyphenylpyruvate dioxygenase
JRI60_08510	COG0404	The glycine cleavage system catalyzes the degradation of glycine
JRI60_08525	COG0023	Translation Initiation Factor
JRI60_08540	COG0473	3-isopropylmalate dehydrogenase activity
JRI60_08560	COG0583	DNA-binding transcription factor activity
JRI60_08565	COG3321	synthase
JRI60_08565	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_08565	COG0604	alcohol dehydrogenase
JRI60_08570	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JRI60_08610	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
JRI60_08620	COG0583	DNA-binding transcription factor activity
JRI60_08650	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_08655	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
JRI60_08660	COG0438	transferase activity, transferring glycosyl groups
JRI60_08670	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
JRI60_08680	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
JRI60_08700	COG0248	Ppx GppA phosphatase
JRI60_08705	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
JRI60_08730	COG0784	Response regulator, receiver
JRI60_08735	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JRI60_08745	COG0515	serine threonine protein kinase
JRI60_08745	COG2815	serine threonine protein kinase
JRI60_08755	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
JRI60_08760	COG2205	protein histidine kinase activity
JRI60_08770	COG0069	glutamate synthase activity
JRI60_08770	COG0070	glutamate synthase
JRI60_08770	COG0067	glutamate synthase
JRI60_08780	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JRI60_08780	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JRI60_08795	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JRI60_08805	COG3394	polysaccharide catabolic process
JRI60_08810	COG0515	serine threonine protein kinase
JRI60_08825	COG0402	S-adenosylhomocysteine deaminase activity
JRI60_08830	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JRI60_08835	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
JRI60_08855	COG3590	peptidase
JRI60_08875	COG2204	response regulator
JRI60_08880	COG1215	transferase activity, transferring glycosyl groups
JRI60_08935	COG2723	6-phospho-beta-galactosidase activity
JRI60_08965	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
JRI60_08970	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
JRI60_08975	COG0784	Response regulator, receiver
JRI60_08985	COG0515	serine threonine protein kinase
JRI60_09065	COG0582	viral genome integration into host DNA
JRI60_09100	COG2433	Pfam Transposase IS66
JRI60_09130	COG0515	serine threonine protein kinase
JRI60_09180	COG0515	serine threonine protein kinase
JRI60_09180	COG2815	serine threonine protein kinase
JRI60_09220	COG1999	signal sequence binding
JRI60_09310	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
JRI60_09330	COG3620	sequence-specific DNA binding
JRI60_09375	COG1845	cytochrome c oxidase, subunit III
JRI60_09380	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JRI60_09385	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
JRI60_09420	COG0437	4 iron, 4 sulfur cluster binding
JRI60_09435	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_09450	COG0693	protein deglycase activity
JRI60_09455	COG2819	hydrolase of the alpha beta superfamily
JRI60_09470	COG0512	Glutamine amidotransferase of anthranilate synthase
JRI60_09480	COG2070	2-Nitropropane dioxygenase
JRI60_09510	COG0406	alpha-ribazole phosphatase activity
JRI60_09515	COG0457	Tetratricopeptide repeat
JRI60_09515	COG0515	serine threonine protein kinase
JRI60_09555	COG0535	radical SAM domain protein
JRI60_09565	COG0159	tryptophan synthase activity
JRI60_09570	COG0133	tryptophan synthase activity
JRI60_09575	COG0135	phosphoribosylanthranilate isomerase activity
JRI60_09580	COG0134	indole-3-glycerol-phosphate synthase activity
JRI60_09585	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JRI60_09615	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
JRI60_09620	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
JRI60_09665	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JRI60_09670	COG0745	RESPONSE REGULATOR receiver
JRI60_09715	COG1278	Cold shock
JRI60_09720	COG0508	dehydrogenase complex catalyzes the overall conversion of
JRI60_09730	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
JRI60_09735	COG2197	response regulator
JRI60_09745	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
JRI60_09760	COG2201	protein-glutamate methylesterase activity
JRI60_09770	COG0542	response to heat
JRI60_09775	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
JRI60_09795	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
JRI60_09835	COG4191	Histidine kinase
JRI60_09845	COG2197	response regulator
JRI60_09850	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JRI60_09855	COG0477	Major facilitator Superfamily
JRI60_09860	COG4191	Histidine kinase
JRI60_09900	COG2815	serine threonine protein kinase
JRI60_09900	COG0515	serine threonine protein kinase
JRI60_09910	COG1131	(ABC) transporter
JRI60_09940	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
JRI60_09965	COG0574	Belongs to the PEP-utilizing enzyme family
JRI60_09965	COG3848	Pyruvate phosphate dikinase
JRI60_09970	COG0515	serine threonine protein kinase
JRI60_09970	COG2815	serine threonine protein kinase
JRI60_10015	COG0037	tRNA processing
JRI60_10045	COG0515	serine threonine protein kinase
JRI60_10055	COG0508	dehydrogenase complex catalyzes the overall conversion of
JRI60_10055	COG0596	Alpha beta hydrolase
JRI60_10065	COG0667	Aldo Keto reductase
JRI60_10090	COG1404	Belongs to the peptidase S8 family
JRI60_10100	COG2815	serine threonine protein kinase
JRI60_10100	COG0515	serine threonine protein kinase
JRI60_10110	COG1733	regulation of RNA biosynthetic process
JRI60_10115	COG0604	alcohol dehydrogenase
JRI60_10185	COG0515	serine threonine protein kinase
JRI60_10205	COG0666	response to abiotic stimulus
JRI60_10230	COG3876	Protein conserved in bacteria
JRI60_10270	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JRI60_10320	COG1196	nuclear chromosome segregation
JRI60_10325	COG2326	polyphosphate kinase activity
JRI60_10330	COG1960	acyl-CoA dehydrogenase activity
JRI60_10365	COG3220	belongs to the UPF0276 family
JRI60_10390	COG1331	Highly conserved protein containing a thioredoxin domain
JRI60_10415	COG1078	dGTPase activity
JRI60_10420	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JRI60_10430	COG2204	response regulator
JRI60_10450	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JRI60_10455	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
JRI60_10470	COG2096	Adenosyltransferase
JRI60_10475	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
JRI60_10485	COG0697	spore germination
JRI60_10495	COG1295	ribonuclease BN
JRI60_10510	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JRI60_10525	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
JRI60_10540	COG0019	diaminopimelate decarboxylase activity
JRI60_10545	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JRI60_10550	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
JRI60_10555	COG0179	Fumarylacetoacetate (FAA) hydrolase
JRI60_10575	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JRI60_10585	COG1960	acyl-CoA dehydrogenase activity
JRI60_10590	COG2086	electron transfer activity
JRI60_10660	COG0300	oxidoreductase activity
JRI60_10675	COG0625	glutathione transferase activity
JRI60_10685	COG0123	including yeast histone deacetylase and acetoin utilization protein
JRI60_10700	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JRI60_10705	COG0805	protein transport
JRI60_10705	COG0805	protein transport
JRI60_10720	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JRI60_10730	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JRI60_10735	COG0813	purine-nucleoside phosphorylase activity
JRI60_10740	COG1012	belongs to the aldehyde dehydrogenase family
JRI60_10745	COG0667	Aldo Keto reductase
JRI60_10780	COG2815	serine threonine protein kinase
JRI60_10780	COG0515	serine threonine protein kinase
JRI60_10795	COG0183	Belongs to the thiolase family
JRI60_10820	COG3384	dioxygenase
JRI60_10840	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
JRI60_10845	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
JRI60_10850	COG3620	sequence-specific DNA binding
JRI60_10930	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JRI60_10935	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JRI60_10950	COG0625	glutathione transferase activity
JRI60_11010	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JRI60_11015	COG1388	LysM domain
JRI60_11015	COG3409	Peptidoglycan-binding domain 1 protein
JRI60_11015	COG5632	N-Acetylmuramoyl-L-alanine amidase
JRI60_11035	COG2815	serine threonine protein kinase
JRI60_11035	COG0515	serine threonine protein kinase
JRI60_11045	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
JRI60_11050	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JRI60_11055	COG0583	DNA-binding transcription factor activity
JRI60_11060	COG0823	Involved in the tonB-independent uptake of proteins
JRI60_11060	COG1506	peptidase
JRI60_11075	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
JRI60_11110	COG0367	asparagine synthase
JRI60_11115	COG1063	alcohol dehydrogenase
JRI60_11145	COG0640	Transcriptional regulator
JRI60_11150	COG2267	carboxylic ester hydrolase activity
JRI60_11155	COG0697	spore germination
JRI60_11210	COG2032	superoxide dismutase activity
JRI60_11225	COG0326	Molecular chaperone. Has ATPase activity
JRI60_11235	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JRI60_11260	COG2205	protein histidine kinase activity
JRI60_11260	COG3437	response regulator, receiver
JRI60_11260	COG3850	Histidine kinase
JRI60_11260	COG4999	Histidine kinase
JRI60_11270	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JRI60_11280	COG0531	amino acid
JRI60_11285	COG2264	protein methyltransferase activity
JRI60_11295	COG2124	cytochrome p450
JRI60_11305	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_11315	COG0367	asparagine synthase
JRI60_11320	COG0736	holo-[acyl-carrier-protein] synthase activity
JRI60_11325	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JRI60_11330	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JRI60_11340	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_11350	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
JRI60_11385	COG1846	Transcriptional regulator
JRI60_11390	COG4191	Histidine kinase
JRI60_11400	COG2339	peptidase activity
JRI60_11410	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
JRI60_11480	COG2879	small protein
JRI60_11485	COG1966	Carbon starvation protein
JRI60_11490	COG2124	cytochrome p450
JRI60_11495	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
JRI60_11500	COG0277	FAD linked oxidase domain protein
JRI60_11535	COG0587	DNA-directed DNA polymerase activity
JRI60_11540	COG1024	Enoyl-CoA hydratase
JRI60_11545	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_11560	COG0058	SHG alpha-glucan phosphorylase activity
JRI60_11575	COG0739	heme binding
JRI60_11580	COG2719	SpoVR family
JRI60_11585	COG2718	Belongs to the UPF0229 family
JRI60_11590	COG2766	serine protein kinase
JRI60_11600	COG4555	ABC transporter
JRI60_11605	COG2205	protein histidine kinase activity
JRI60_11605	COG0784	Response regulator, receiver
JRI60_11615	COG3437	response regulator, receiver
JRI60_11620	COG4191	Histidine kinase
JRI60_11640	COG2204	response regulator
JRI60_11645	COG3852	Histidine kinase
JRI60_11660	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JRI60_11670	COG0583	DNA-binding transcription factor activity
JRI60_11675	COG1741	Belongs to the pirin family
JRI60_11680	COG0776	regulation of translation
JRI60_11700	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
JRI60_11700	COG2755	lipolytic protein G-D-S-L family
JRI60_11725	COG1309	transcriptional regulator
JRI60_11755	COG0666	response to abiotic stimulus
JRI60_11770	COG0515	serine threonine protein kinase
JRI60_11770	COG2815	serine threonine protein kinase
JRI60_11800	COG5002	protein histidine kinase activity
JRI60_11810	COG2205	protein histidine kinase activity
JRI60_11815	COG0745	RESPONSE REGULATOR receiver
JRI60_11830	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JRI60_11880	COG1192	Involved in chromosome partitioning
JRI60_11900	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JRI60_11905	COG0584	glycerophosphoryl diester phosphodiesterase
JRI60_11915	COG0793	Belongs to the peptidase S41A family
JRI60_11925	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
JRI60_11930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JRI60_11930	COG4191	Histidine kinase
JRI60_11950	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JRI60_12005	COG0220	tRNA (guanine-N7-)-methyltransferase activity
JRI60_12015	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JRI60_12025	COG1459	type II secretion system
JRI60_12030	COG3852	Histidine kinase
JRI60_12045	COG1131	(ABC) transporter
JRI60_12055	COG4968	Prepilin-type N-terminal cleavage methylation domain
JRI60_12060	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
JRI60_12065	COG4191	Histidine kinase
JRI60_12070	COG2204	response regulator
JRI60_12110	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JRI60_12115	COG0511	ligase activity, forming carbon-carbon bonds
JRI60_12120	COG0439	Biotin carboxylase
JRI60_12130	COG3409	Peptidoglycan-binding domain 1 protein
JRI60_12130	COG3267	Type II secretory pathway component ExeA
JRI60_12185	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
JRI60_12200	COG2162	N-hydroxyarylamine O-acetyltransferase activity
JRI60_12205	COG1902	pentaerythritol trinitrate reductase activity
JRI60_12215	COG0248	Ppx GppA phosphatase
JRI60_12240	COG0823	Involved in the tonB-independent uptake of proteins
JRI60_12255	COG0811	peptide transport
JRI60_12265	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
JRI60_12280	COG2884	Cell division ATP-binding protein ftsE
JRI60_12285	COG2177	Part of the ABC transporter FtsEX involved in
JRI60_12290	COG4942	peptidase
JRI60_12295	COG0673	inositol 2-dehydrogenase activity
JRI60_12300	COG2267	carboxylic ester hydrolase activity
JRI60_12305	COG0793	Belongs to the peptidase S41A family
JRI60_12310	COG0583	DNA-binding transcription factor activity
JRI60_12315	COG3118	belongs to the thioredoxin family
JRI60_12320	COG0024	Methionine aminopeptidase
JRI60_12350	COG0753	catalase activity
JRI60_12370	COG1181	Belongs to the D-alanine--D-alanine ligase family
JRI60_12375	COG1215	transferase activity, transferring glycosyl groups
JRI60_12400	COG0552	protein localization to endoplasmic reticulum
JRI60_12475	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
JRI60_12480	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
JRI60_12490	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JRI60_12505	COG1079	Belongs to the binding-protein-dependent transport system permease family
JRI60_12510	COG4603	Belongs to the binding-protein-dependent transport system permease family
JRI60_12515	COG3845	ABC transporter
JRI60_12540	COG0667	Aldo Keto reductase
JRI60_12550	COG0402	S-adenosylhomocysteine deaminase activity
JRI60_12595	COG1136	(ABC) transporter
JRI60_12595	COG0577	efflux transmembrane transporter activity
JRI60_12610	COG0515	serine threonine protein kinase
JRI60_12620	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
JRI60_12625	COG5002	protein histidine kinase activity
JRI60_12650	COG0791	NLP P60 protein
JRI60_12650	COG1388	LysM domain
JRI60_12665	COG0668	transmembrane transport
JRI60_12675	COG0517	IMP dehydrogenase activity
JRI60_12695	COG3541	Predicted nucleotidyltransferase
JRI60_12735	COG0596	Alpha beta hydrolase
JRI60_12740	COG0714	Associated with various cellular activities
JRI60_12780	COG1136	(ABC) transporter
JRI60_12805	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JRI60_12815	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
JRI60_12865	COG0577	efflux transmembrane transporter activity
JRI60_12890	COG4669	(LipO)protein
JRI60_12900	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
JRI60_12910	COG4790	Type iii secretion
JRI60_12915	COG1987	bacterial-type flagellum assembly
JRI60_12920	COG1684	flagellar biosynthetic protein fliR
JRI60_12925	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
JRI60_12930	COG4789	Type iii secretion
JRI60_12940	COG1295	ribonuclease BN
JRI60_12945	COG1530	ribonuclease E activity
JRI60_12945	COG1530	ribonuclease E activity
JRI60_12955	COG1254	Belongs to the acylphosphatase family
JRI60_12960	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JRI60_12965	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
JRI60_12975	COG0628	permease
JRI60_12985	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JRI60_12985	COG0519	Catalyzes the synthesis of GMP from XMP
JRI60_13000	COG1454	alcohol dehydrogenase
JRI60_13045	COG1960	acyl-CoA dehydrogenase activity
JRI60_13060	COG2001	Belongs to the MraZ family
JRI60_13070	COG0275	rRNA processing
JRI60_13075	COG3116	cell division
JRI60_13085	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JRI60_13090	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JRI60_13095	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JRI60_13100	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JRI60_13105	COG0772	Belongs to the SEDS family
JRI60_13110	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JRI60_13115	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JRI60_13120	COG0812	UDP-N-acetylmuramate dehydrogenase activity
JRI60_13125	COG1181	Belongs to the D-alanine--D-alanine ligase family
JRI60_13130	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
JRI60_13150	COG0515	serine threonine protein kinase
JRI60_13150	COG2815	serine threonine protein kinase
JRI60_13170	COG4372	Transposase
JRI60_13215	COG5464	transposase or invertase
JRI60_13220	COG1672	PFAM Archaeal ATPase
JRI60_13220	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
JRI60_13250	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
JRI60_13255	COG0745	RESPONSE REGULATOR receiver
JRI60_13280	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
JRI60_13290	COG0439	Biotin carboxylase
JRI60_13295	COG0511	ligase activity, forming carbon-carbon bonds
JRI60_13305	COG0745	RESPONSE REGULATOR receiver
JRI60_13310	COG0842	Transport permease protein
JRI60_13310	COG1131	(ABC) transporter
JRI60_13310	COG1716	ATPase activity
JRI60_13325	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
JRI60_13335	COG0842	Transport permease protein
JRI60_13350	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
JRI60_13360	COG0667	Aldo Keto reductase
JRI60_13400	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
JRI60_13480	COG1929	Belongs to the glycerate kinase type-1 family
JRI60_13490	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
JRI60_13505	COG3030	protein affecting phage T7 exclusion by the F plasmid
JRI60_13535	COG0626	cystathionine gamma-synthase activity
JRI60_13560	COG0477	Major facilitator Superfamily
JRI60_13580	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
JRI60_13585	COG0631	protein serine/threonine phosphatase activity
JRI60_13595	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
JRI60_13610	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
JRI60_13615	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
JRI60_13630	COG1428	Deoxynucleoside kinase
JRI60_13635	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
JRI60_13640	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
JRI60_13645	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
JRI60_13665	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
JRI60_13665	COG2199	diguanylate cyclase activity
JRI60_13685	COG0779	Required for maturation of 30S ribosomal subunits
JRI60_13715	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JRI60_13725	COG1185	polyribonucleotide nucleotidyltransferase activity
JRI60_13730	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JRI60_13740	COG2815	serine threonine protein kinase
JRI60_13740	COG0515	serine threonine protein kinase
JRI60_13745	COG0756	dUTP diphosphatase activity
JRI60_13750	COG0739	heme binding
JRI60_13760	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
JRI60_13780	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JRI60_13795	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JRI60_13830	COG0612	Peptidase, M16
JRI60_13910	COG1484	DNA-dependent DNA replication
JRI60_13920	COG4584	PFAM Integrase catalytic
JRI60_13925	COG1484	DNA-dependent DNA replication
JRI60_13930	COG4584	PFAM Integrase catalytic
JRI60_13985	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JRI60_13990	COG1960	acyl-CoA dehydrogenase activity
JRI60_13995	COG2815	serine threonine protein kinase
JRI60_13995	COG0515	serine threonine protein kinase
JRI60_14050	COG1960	acyl-CoA dehydrogenase activity
JRI60_14055	COG2202	Pas domain
JRI60_14055	COG2205	protein histidine kinase activity
JRI60_14110	COG4566	intracellular signal transduction
JRI60_14115	COG4191	Histidine kinase
JRI60_14140	COG1741	Belongs to the pirin family
JRI60_14170	COG3250	beta-galactosidase activity
JRI60_14235	COG1764	response to oxidative stress
JRI60_14245	COG0596	Alpha beta hydrolase
JRI60_14250	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
JRI60_14260	COG0785	Cytochrome C biogenesis protein
JRI60_14285	COG1309	transcriptional regulator
JRI60_14310	COG3344	reverse transcriptase
JRI60_14315	COG3290	protein histidine kinase activity
JRI60_14340	COG1012	belongs to the aldehyde dehydrogenase family
JRI60_14350	COG0183	Belongs to the thiolase family
JRI60_14355	COG1960	acyl-CoA dehydrogenase activity
JRI60_14360	COG1960	acyl-CoA dehydrogenase activity
JRI60_14370	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_14380	COG1024	Enoyl-CoA hydratase
JRI60_14390	COG1960	acyl-CoA dehydrogenase activity
JRI60_14400	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_14405	COG2010	Cytochrome c
JRI60_14430	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JRI60_14440	COG1320	monovalent cation:proton antiporter activity
JRI60_14445	COG2212	antiporter activity
JRI60_14450	COG1863	multisubunit Na H antiporter MnhE subunit
JRI60_14455	COG0651	ATP synthesis coupled electron transport
JRI60_14460	COG1006	Multisubunit Na H antiporter MnhC subunit
JRI60_14465	COG2111	Na H antiporter
JRI60_14465	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JRI60_14490	COG2072	flavoprotein involved in K transport
JRI60_14500	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JRI60_14505	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JRI60_14515	COG0515	serine threonine protein kinase
JRI60_14515	COG2815	serine threonine protein kinase
JRI60_14520	COG2226	methyltransferase
JRI60_14525	COG0789	Transcriptional regulator
JRI60_14540	COG2815	serine threonine protein kinase
JRI60_14540	COG0515	serine threonine protein kinase
JRI60_14555	COG5507	3-demethylubiquinone-9 3-methyltransferase
JRI60_14605	COG0515	serine threonine protein kinase
JRI60_14635	COG1573	uracil-dna glycosylase
JRI60_14645	COG2205	protein histidine kinase activity
JRI60_14650	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
JRI60_14655	COG0412	Dienelactone hydrolase
JRI60_14670	COG5002	protein histidine kinase activity
JRI60_14685	COG4941	Belongs to the sigma-70 factor family
JRI60_14690	COG3795	YCII-related domain
JRI60_14695	COG0501	Belongs to the peptidase M48B family
JRI60_14715	COG1132	(ABC) transporter
JRI60_14720	COG1132	(ABC) transporter
JRI60_14725	COG2137	regulation of response to DNA damage stimulus
JRI60_14755	COG2124	cytochrome p450
JRI60_14765	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
JRI60_14770	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
JRI60_14775	COG1492	cobalamin metabolic process
JRI60_14780	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JRI60_14785	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
JRI60_14805	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
JRI60_14870	COG1122	ATPase activity
JRI60_14885	COG0310	cobalt ion transport
JRI60_14905	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_14950	COG4191	Histidine kinase
JRI60_14960	COG2706	6-phosphogluconolactonase activity
JRI60_14970	COG0095	Lipoate-protein ligase
JRI60_14980	COG3002	Belongs to the UPF0753 family
JRI60_14985	COG1007	ATP synthesis coupled electron transport
JRI60_14995	COG0659	secondary active sulfate transmembrane transporter activity
JRI60_15005	COG0596	Alpha beta hydrolase
JRI60_15020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JRI60_15025	COG3227	Zinc metalloprotease (Elastase)
JRI60_15040	COG4953	penicillin-binding protein 1C
JRI60_15045	COG2373	Large extracellular alpha-helical protein
JRI60_15090	COG4968	Prepilin-type N-terminal cleavage methylation domain
JRI60_15095	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JRI60_15120	COG0681	Belongs to the peptidase S26 family
JRI60_15125	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JRI60_15125	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JRI60_15170	COG0300	oxidoreductase activity
JRI60_15185	COG2205	protein histidine kinase activity
JRI60_15195	COG0531	amino acid
JRI60_15225	COG1454	alcohol dehydrogenase
JRI60_15240	COG1408	metallophosphoesterase
JRI60_15245	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JRI60_15270	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
JRI60_15280	COG0840	transmembrane signaling receptor activity
JRI60_15290	COG2201	protein-glutamate methylesterase activity
JRI60_15295	COG0745	RESPONSE REGULATOR receiver
JRI60_15355	COG0693	protein deglycase activity
JRI60_15360	COG0546	phosphoglycolate phosphatase activity
JRI60_15365	COG1032	radical SAM domain protein
JRI60_15375	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
JRI60_15385	COG0745	RESPONSE REGULATOR receiver
JRI60_15385	COG2205	protein histidine kinase activity
JRI60_15385	COG3292	Two component regulator propeller
JRI60_15400	COG2363	Small membrane protein
JRI60_15410	COG1506	peptidase
JRI60_15410	COG0823	Involved in the tonB-independent uptake of proteins
JRI60_15425	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JRI60_15435	COG1045	serine acetyltransferase
JRI60_15480	COG1362	aminopeptidase activity
JRI60_15495	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JRI60_15505	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
JRI60_15520	COG0631	protein serine/threonine phosphatase activity
JRI60_15560	COG0515	serine threonine protein kinase
JRI60_15560	COG2815	serine threonine protein kinase
JRI60_15570	COG0076	glutamate decarboxylase activity
JRI60_15585	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
JRI60_15625	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JRI60_15655	COG1301	dicarboxylic acid transport
JRI60_15660	COG1047	Peptidyl-prolyl cis-trans
JRI60_15685	COG0488	(ABC) transporter
JRI60_15690	COG0488	(ABC) transporter
JRI60_15695	COG0513	Belongs to the DEAD box helicase family
JRI60_15700	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JRI60_15710	COG1187	pseudouridine synthase activity
JRI60_15740	COG2373	Large extracellular alpha-helical protein
JRI60_15750	COG0784	Response regulator, receiver
JRI60_15755	COG4251	negative regulation of phosphorylation
JRI60_15760	COG3852	Histidine kinase
JRI60_15765	COG0514	ATP-dependent DNA helicase (RecQ)
JRI60_15775	COG0644	oxidoreductase
JRI60_15785	COG4953	penicillin-binding protein 1C
JRI60_15800	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
JRI60_15800	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JRI60_15810	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JRI60_15820	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_15845	COG4943	cyclic-guanylate-specific phosphodiesterase activity
JRI60_15865	COG1136	(ABC) transporter
JRI60_15865	COG0577	efflux transmembrane transporter activity
JRI60_15875	COG1136	(ABC) transporter
JRI60_15910	COG1191	sigma factor activity
JRI60_15920	COG1766	The M ring may be actively involved in energy transduction
JRI60_15930	COG1317	bacterial-type flagellum organization
JRI60_15935	COG1157	protein secretion by the type III secretion system
JRI60_15950	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
JRI60_15950	COG1776	CheC inhibitor of MCP methylation
JRI60_15960	COG1338	Plays a role in the flagellum-specific transport system
JRI60_15965	COG1987	bacterial-type flagellum assembly
JRI60_15975	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
JRI60_15980	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
JRI60_16025	COG4789	Type iii secretion
JRI60_16035	COG1716	ATPase activity
JRI60_16070	COG0515	serine threonine protein kinase
JRI60_16070	COG2815	serine threonine protein kinase
JRI60_16080	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_16085	COG1169	isochorismate synthase
JRI60_16090	COG1021	2,3-dihydroxybenzoate-AMP ligase
JRI60_16095	COG1535	isochorismatase
JRI60_16095	COG3433	isochorismatase activity
JRI60_16100	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JRI60_16105	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
JRI60_16120	COG0811	peptide transport
JRI60_16140	COG0515	serine threonine protein kinase
JRI60_16140	COG2815	serine threonine protein kinase
JRI60_16145	COG2815	serine threonine protein kinase
JRI60_16145	COG0515	serine threonine protein kinase
JRI60_16165	COG0714	Associated with various cellular activities
JRI60_16185	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
JRI60_16215	COG3973	AAA domain
JRI60_16235	COG0604	alcohol dehydrogenase
JRI60_16235	COG3321	synthase
JRI60_16235	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_16255	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
JRI60_16275	COG4585	Histidine kinase
JRI60_16285	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
JRI60_16290	COG0616	signal peptide processing
JRI60_16305	COG0187	DNA topoisomerase II activity
JRI60_16310	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JRI60_16320	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JRI60_16330	COG4990	cell redox homeostasis
JRI60_16330	COG3591	Belongs to the peptidase S1B family
JRI60_16340	COG1595	DNA-templated transcription, initiation
JRI60_16410	COG1459	type II secretion system
JRI60_16415	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JRI60_16445	COG1858	cytochrome C peroxidase
JRI60_16475	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
JRI60_16510	COG0737	Belongs to the 5'-nucleotidase family
JRI60_16510	COG1525	nuclease
JRI60_16510	COG4085	toxin activity
JRI60_16515	COG3275	phosphorelay sensor kinase activity
JRI60_16520	COG3279	Response regulator of the LytR AlgR family
JRI60_16535	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JRI60_16540	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
JRI60_16575	COG0416	fatty acid biosynthetic process
JRI60_16605	COG0437	4 iron, 4 sulfur cluster binding
JRI60_16620	COG0243	molybdopterin cofactor binding
JRI60_16655	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JRI60_16665	COG0564	pseudouridine synthase activity
JRI60_16680	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JRI60_16685	COG4589	Belongs to the CDS family
JRI60_16690	COG0750	zinc metalloprotease
JRI60_16695	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
JRI60_16700	COG1214	PFAM Peptidase M22, glycoprotease
JRI60_16705	COG0840	transmembrane signaling receptor activity
JRI60_16715	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JRI60_16735	COG0314	molybdopterin synthase activity
JRI60_16745	COG0750	zinc metalloprotease
JRI60_16770	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JRI60_16790	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JRI60_16790	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JRI60_16810	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
JRI60_16830	COG0515	serine threonine protein kinase
JRI60_16840	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JRI60_16845	COG0316	Belongs to the HesB IscA family
JRI60_16850	COG1607	acyl-coa hydrolase
JRI60_16860	COG0584	glycerophosphoryl diester phosphodiesterase
JRI60_16895	COG4106	trans-aconitate 2-methyltransferase activity
JRI60_16895	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
JRI60_16905	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
JRI60_16930	COG3104	oligopeptide transport
JRI60_16935	COG3104	oligopeptide transport
JRI60_16990	COG0596	Alpha beta hydrolase
JRI60_16995	COG4335	DNA alkylation repair
JRI60_17040	COG0625	glutathione transferase activity
JRI60_17045	COG0583	DNA-binding transcription factor activity
JRI60_17105	COG1250	3-hydroxyacyl-CoA dehydrogenase
JRI60_17105	COG1024	Enoyl-CoA hydratase
JRI60_17110	COG0183	Belongs to the thiolase family
JRI60_17140	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JRI60_17145	COG2204	response regulator
JRI60_17150	COG3852	Histidine kinase
JRI60_17170	COG2205	protein histidine kinase activity
JRI60_17170	COG4191	Histidine kinase
JRI60_17170	COG0745	RESPONSE REGULATOR receiver
JRI60_17190	COG2832	Protein of unknown function (DUF454)
JRI60_17205	COG2943	transferase activity, transferring hexosyl groups
JRI60_17215	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
JRI60_17220	COG0667	Aldo Keto reductase
JRI60_17260	COG0402	S-adenosylhomocysteine deaminase activity
JRI60_17280	COG0745	RESPONSE REGULATOR receiver
JRI60_17290	COG0515	serine threonine protein kinase
JRI60_17315	COG2815	serine threonine protein kinase
JRI60_17315	COG0515	serine threonine protein kinase
JRI60_17320	COG1396	sequence-specific DNA binding
JRI60_17335	COG0515	serine threonine protein kinase
JRI60_17385	COG2354	Protein conserved in bacteria
JRI60_17455	COG3940	Belongs to the glycosyl hydrolase 43 family
JRI60_17460	COG3940	Belongs to the glycosyl hydrolase 43 family
JRI60_17475	COG1069	ribulokinase activity
JRI60_17485	COG1879	ABC-type sugar transport system periplasmic component
JRI60_17490	COG1129	ABC transporter
JRI60_17495	COG1172	Belongs to the binding-protein-dependent transport system permease family
JRI60_17500	COG1172	Belongs to the binding-protein-dependent transport system permease family
JRI60_17540	COG0071	Belongs to the small heat shock protein (HSP20) family
JRI60_17545	COG0625	glutathione transferase activity
JRI60_17575	COG1595	DNA-templated transcription, initiation
JRI60_17580	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_17615	COG1484	DNA-dependent DNA replication
JRI60_17620	COG4584	PFAM Integrase catalytic
JRI60_17655	COG0515	serine threonine protein kinase
JRI60_17655	COG2815	serine threonine protein kinase
JRI60_17705	COG0625	glutathione transferase activity
JRI60_17845	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JRI60_17845	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JRI60_17860	COG4771	TonB-dependent receptor
JRI60_17870	COG0542	response to heat
JRI60_17895	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
JRI60_17905	COG0305	Participates in initiation and elongation during chromosome replication
JRI60_17910	COG0359	binds to the 23S rRNA
JRI60_17915	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
JRI60_17920	COG0360	Binds together with S18 to 16S ribosomal RNA
JRI60_17925	COG0193	aminoacyl-tRNA hydrolase activity
JRI60_17930	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
JRI60_17935	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JRI60_17940	COG2088	sporulation resulting in formation of a cellular spore
JRI60_17955	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JRI60_17980	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
JRI60_17990	COG0745	RESPONSE REGULATOR receiver
JRI60_17995	COG4771	TonB-dependent receptor
JRI60_18010	COG2378	regulation of single-species biofilm formation
JRI60_18035	COG3227	Zinc metalloprotease (Elastase)
JRI60_18055	COG2205	protein histidine kinase activity
JRI60_18055	COG0784	Response regulator, receiver
JRI60_18060	COG3507	Belongs to the glycosyl hydrolase 43 family
JRI60_18065	COG2124	cytochrome p450
JRI60_18100	COG3507	Belongs to the glycosyl hydrolase 43 family
JRI60_18120	COG0300	oxidoreductase activity
JRI60_18125	COG1773	rubredoxin
JRI60_18135	COG0612	Peptidase, M16
JRI60_18140	COG5002	protein histidine kinase activity
JRI60_18165	COG1304	FMN binding
JRI60_18195	COG1063	alcohol dehydrogenase
JRI60_18200	COG0667	Aldo Keto reductase
JRI60_18255	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
JRI60_18285	COG0583	DNA-binding transcription factor activity
JRI60_18300	COG0300	oxidoreductase activity
JRI60_18315	COG0232	Belongs to the dGTPase family. Type 2 subfamily
JRI60_18320	COG1335	isochorismatase
JRI60_18330	COG2124	cytochrome p450
JRI60_18340	COG1309	transcriptional regulator
JRI60_18345	COG2124	cytochrome p450
JRI60_18350	COG5002	protein histidine kinase activity
JRI60_18375	COG0633	Ferredoxin
JRI60_18385	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
JRI60_18390	COG0316	Belongs to the HesB IscA family
JRI60_18395	COG0822	iron-sulfur transferase activity
JRI60_18400	COG1104	cysteine desulfurase activity
JRI60_18420	COG2239	Acts as a magnesium transporter
JRI60_18470	COG2211	Major facilitator Superfamily
JRI60_18475	COG4232	protein-disulfide reductase activity
JRI60_18505	COG1653	transport
JRI60_18540	COG0534	Mate efflux family protein
JRI60_18545	COG4650	regulator
JRI60_18550	COG1690	Belongs to the RtcB family
JRI60_18555	COG0430	RNA-3'-phosphate cyclase activity
JRI60_18570	COG0835	chemotaxis
JRI60_18570	COG0784	Response regulator, receiver
JRI60_18575	COG0217	transcriptional regulatory protein
JRI60_18580	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
JRI60_18585	COG0632	four-way junction helicase activity
JRI60_18595	COG0189	ligase activity
JRI60_18610	COG0475	glutathione-regulated potassium exporter activity
JRI60_18615	COG0475	glutathione-regulated potassium exporter activity
JRI60_18620	COG1396	sequence-specific DNA binding
JRI60_18650	COG1063	alcohol dehydrogenase
JRI60_18655	COG2255	four-way junction helicase activity
JRI60_18665	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
JRI60_18670	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JRI60_18670	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
JRI60_18690	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JRI60_18700	COG0730	response to heat
JRI60_18725	COG3800	Transcriptional regulator
JRI60_18725	COG1396	sequence-specific DNA binding
JRI60_18740	COG3220	belongs to the UPF0276 family
JRI60_18775	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
JRI60_18830	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JRI60_18835	COG2890	protein-(glutamine-N5) methyltransferase activity
JRI60_18840	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
JRI60_18850	COG1253	flavin adenine dinucleotide binding
JRI60_18870	COG2205	protein histidine kinase activity
JRI60_18880	COG1609	Transcriptional regulator
JRI60_18900	COG0583	DNA-binding transcription factor activity
JRI60_18910	COG1196	nuclear chromosome segregation
JRI60_18925	COG3829	transcription factor binding
JRI60_18940	COG0459	protein refolding
JRI60_18945	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
JRI60_18965	COG1758	RNA polymerase activity
JRI60_18970	COG4191	Histidine kinase
JRI60_18975	COG4377	Putative membrane peptidase family (DUF2324)
JRI60_18980	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JRI60_18990	COG0683	leucine binding
JRI60_18995	COG0477	Major facilitator Superfamily
JRI60_19015	COG1595	DNA-templated transcription, initiation
JRI60_19050	COG1131	(ABC) transporter
JRI60_19135	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JRI60_19165	COG0318	PFAM AMP-dependent synthetase and ligase
JRI60_19175	COG0463	Glycosyl transferase, family 2
JRI60_19225	COG2986	histidine ammonia-lyase
JRI60_19335	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JRI60_19370	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
JRI60_19395	COG2234	aminopeptidase activity
JRI60_19405	COG1253	flavin adenine dinucleotide binding
JRI60_19410	COG2205	protein histidine kinase activity
JRI60_19410	COG5002	protein histidine kinase activity
JRI60_19410	COG0784	Response regulator, receiver
JRI60_19415	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
JRI60_19425	COG0704	Plays a role in the regulation of phosphate uptake
JRI60_19430	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JRI60_19435	COG0581	inorganic phosphate transmembrane transporter activity
JRI60_19440	COG0573	inorganic phosphate transmembrane transporter activity
JRI60_19445	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
JRI60_19460	COG2062	phosphohistidine phosphatase, SixA
JRI60_19475	COG5002	protein histidine kinase activity
JRI60_19480	COG0745	RESPONSE REGULATOR receiver
JRI60_19500	COG0668	transmembrane transport
JRI60_19505	COG3387	PFAM Glycoside hydrolase 15-related
JRI60_19510	COG0333	Belongs to the bacterial ribosomal protein bL32 family
JRI60_19515	COG0416	fatty acid biosynthetic process
JRI60_19520	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JRI60_19535	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JRI60_19540	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JRI60_19545	COG0698	ribose 5-phosphate isomerase
JRI60_19550	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JRI60_19555	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
JRI60_19560	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JRI60_19560	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JRI60_19605	COG2885	chlorophyll binding
JRI60_19610	COG0596	Alpha beta hydrolase
JRI60_19660	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JRI60_19660	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JRI60_19665	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
JRI60_19670	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JRI60_19680	COG0745	RESPONSE REGULATOR receiver
JRI60_19685	COG0643	Histidine kinase
JRI60_19685	COG2198	Histidine kinase
JRI60_19685	COG0784	Response regulator, receiver
JRI60_19685	COG0643	Histidine kinase
JRI60_19685	COG0784	Response regulator, receiver
JRI60_19685	COG2198	Histidine kinase
JRI60_19705	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
JRI60_19710	COG2201	protein-glutamate methylesterase activity
JRI60_19725	COG0784	Response regulator, receiver
JRI60_19730	COG0667	Aldo Keto reductase
JRI60_19735	COG3148	PFAM DTW domain containing protein
JRI60_19770	COG0745	RESPONSE REGULATOR receiver
JRI60_19775	COG0495	leucyl-tRNA aminoacylation
JRI60_19795	COG3956	TIGRFAM MazG family protein
JRI60_19805	COG0457	Tetratricopeptide repeat
JRI60_19815	COG1480	7TM receptor with intracellular HD hydrolase
JRI60_19820	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
JRI60_19820	COG0662	Cupin 2, conserved barrel domain protein
JRI60_19835	COG1846	Transcriptional regulator
JRI60_19850	COG3275	phosphorelay sensor kinase activity
JRI60_19855	COG3279	Response regulator of the LytR AlgR family
JRI60_19885	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
JRI60_19895	COG1136	(ABC) transporter
JRI60_19900	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JRI60_19910	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JRI60_19915	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JRI60_19940	COG2095	MarC family integral membrane protein
JRI60_19945	COG0463	Glycosyl transferase, family 2
JRI60_19950	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JRI60_19975	COG1132	(ABC) transporter
JRI60_19985	COG3227	Zinc metalloprotease (Elastase)
JRI60_19990	COG1519	Transferase
JRI60_20000	COG1663	tetraacyldisaccharide 4'-kinase activity
JRI60_20010	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
JRI60_20010	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
JRI60_20015	COG2835	tetraacyldisaccharide 4'-kinase activity
JRI60_20025	COG1561	YicC-like family, N-terminal region
JRI60_20030	COG0194	GDP metabolic process
JRI60_20060	COG0515	serine threonine protein kinase
JRI60_20090	COG2385	sporulation resulting in formation of a cellular spore
JRI60_20095	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
JRI60_20100	COG0343	queuine tRNA-ribosyltransferase activity
JRI60_20105	COG1862	Preprotein translocase
JRI60_20110	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JRI60_20115	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JRI60_20125	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
JRI60_20125	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
JRI60_20145	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
JRI60_20150	COG1597	lipid kinase activity
JRI60_20165	COG1193	negative regulation of DNA recombination
JRI60_20170	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JRI60_20190	COG0714	Associated with various cellular activities
JRI60_20200	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JRI60_20215	COG2030	dehydratase
JRI60_20225	COG1960	acyl-CoA dehydrogenase activity
JRI60_20255	COG0444	Belongs to the ABC transporter superfamily
JRI60_20260	COG4608	Belongs to the ABC transporter superfamily
JRI60_20330	COG1716	ATPase activity
JRI60_20340	COG1570	exodeoxyribonuclease VII activity
JRI60_20350	COG0745	RESPONSE REGULATOR receiver
JRI60_20360	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
JRI60_20365	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
JRI60_20400	COG1695	Transcriptional regulator
JRI60_20405	COG0815	Transfers the fatty acyl group on membrane lipoproteins
JRI60_20415	COG0515	serine threonine protein kinase
JRI60_20430	COG3387	PFAM Glycoside hydrolase 15-related
JRI60_20450	COG2226	methyltransferase
JRI60_20525	COG4771	TonB-dependent receptor
JRI60_20555	COG0583	DNA-binding transcription factor activity
JRI60_20565	COG0515	serine threonine protein kinase
JRI60_20570	COG0583	DNA-binding transcription factor activity
JRI60_20575	COG2814	Major facilitator Superfamily
JRI60_20680	COG0596	Alpha beta hydrolase
JRI60_20740	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
JRI60_20755	COG0705	Rhomboid family
JRI60_20765	COG0741	lytic transglycosylase activity
JRI60_20850	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JRI60_20855	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
JRI60_20880	COG1295	ribonuclease BN
JRI60_20885	COG0488	(ABC) transporter
JRI60_20915	COG2815	serine threonine protein kinase
JRI60_20915	COG0515	serine threonine protein kinase
JRI60_20940	COG0343	queuine tRNA-ribosyltransferase activity
JRI60_20965	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
JRI60_20965	COG0546	phosphoglycolate phosphatase activity
JRI60_20985	COG2175	clavaminate synthase activity
JRI60_21005	COG0022	dehydrogenase e1 component
JRI60_21015	COG2208	phosphoserine phosphatase activity
JRI60_21015	COG2770	Histidine kinase
JRI60_21030	COG4771	TonB-dependent receptor
JRI60_21040	COG0515	serine threonine protein kinase
JRI60_21060	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JRI60_21085	COG0673	inositol 2-dehydrogenase activity
JRI60_21125	COG1262	PFAM Formylglycine-generating sulfatase enzyme
JRI60_21130	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JRI60_21130	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JRI60_21140	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JRI60_21145	COG0515	serine threonine protein kinase
JRI60_21170	COG0443	Heat shock 70 kDa protein
JRI60_21230	COG4584	PFAM Integrase catalytic
JRI60_21240	COG4584	PFAM Integrase catalytic
JRI60_21245	COG1484	DNA-dependent DNA replication
JRI60_21275	COG1484	DNA-dependent DNA replication
JRI60_21280	COG4584	PFAM Integrase catalytic
JRI60_21285	COG1484	DNA-dependent DNA replication
JRI60_21290	COG4584	PFAM Integrase catalytic
JRI60_21335	COG0459	protein refolding
JRI60_21350	COG3706	GGDEF domain
JRI60_21365	COG0525	valine-tRNA ligase activity
JRI60_21375	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
JRI60_21380	COG0824	Thioesterase
JRI60_21385	COG1494	fructose-1,6-bisphosphatase
JRI60_21400	COG1397	ADP-ribosylglycohydrolase
JRI60_21405	COG0148	phosphopyruvate hydratase activity
JRI60_21410	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
JRI60_21415	COG0739	heme binding
JRI60_21430	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JRI60_21435	COG5002	protein histidine kinase activity
JRI60_21485	COG1215	transferase activity, transferring glycosyl groups
JRI60_21535	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
JRI60_21555	COG0583	DNA-binding transcription factor activity
JRI60_21625	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JRI60_21635	COG0010	Belongs to the arginase family
JRI60_21640	COG0604	alcohol dehydrogenase
JRI60_21640	COG3321	synthase
JRI60_21645	COG2239	Acts as a magnesium transporter
JRI60_21650	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
JRI60_21655	COG4464	protein tyrosine phosphatase activity
JRI60_21670	COG2119	membrane
JRI60_21675	COG5002	protein histidine kinase activity
JRI60_21730	COG0631	protein serine/threonine phosphatase activity
JRI60_21740	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JRI60_21745	COG1360	Flagellar Motor Protein
JRI60_21755	COG1573	uracil-dna glycosylase
JRI60_21765	COG0604	alcohol dehydrogenase
JRI60_21770	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
JRI60_21780	COG5012	cobalamin binding
JRI60_21785	COG1607	acyl-coa hydrolase
JRI60_21790	COG3246	L-lysine catabolic process to acetate
JRI60_21810	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JRI60_21815	COG0154	amidase activity
JRI60_21845	COG1262	PFAM Formylglycine-generating sulfatase enzyme
JRI60_21855	COG0596	Alpha beta hydrolase
JRI60_21860	COG2226	methyltransferase
JRI60_21885	COG0697	spore germination
JRI60_21895	COG1819	glycosyl
JRI60_21925	COG2814	Major facilitator Superfamily
JRI60_21940	COG1605	Chorismate mutase
JRI60_21940	COG0077	Prephenate dehydratase
JRI60_21955	COG1278	Cold shock
JRI60_21980	COG1063	alcohol dehydrogenase
JRI60_21995	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
JRI60_22015	COG0840	transmembrane signaling receptor activity
JRI60_22030	COG0300	oxidoreductase activity
JRI60_22115	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JRI60_22165	COG0037	tRNA processing
JRI60_22170	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JRI60_22175	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
JRI60_22180	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JRI60_22185	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
JRI60_22190	COG0736	holo-[acyl-carrier-protein] synthase activity
JRI60_22195	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
JRI60_22195	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
JRI60_22200	COG0802	atpase or kinase
JRI60_22215	COG2202	Pas domain
JRI60_22215	COG2205	protein histidine kinase activity
JRI60_22225	COG1228	amidohydrolase
JRI60_22230	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
JRI60_22235	COG0137	argininosuccinate synthase activity
JRI60_22255	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
JRI60_22260	COG4968	Prepilin-type N-terminal cleavage methylation domain
JRI60_22275	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JRI60_22280	COG1138	Cytochrome C-type biogenesis protein
JRI60_22285	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
JRI60_22295	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JRI60_22305	COG4133	protoheme IX ABC transporter activity
JRI60_22330	COG0438	transferase activity, transferring glycosyl groups
JRI60_22365	COG0277	FAD linked oxidase domain protein
JRI60_22445	COG0564	pseudouridine synthase activity
JRI60_22460	COG1819	glycosyl
JRI60_22480	COG0471	metal ion transport
JRI60_22495	COG3781	membrane
JRI60_22500	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
JRI60_22515	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JRI60_22550	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_22585	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JRI60_22590	COG0598	Magnesium transport protein CorA
JRI60_22675	COG2937	Belongs to the GPAT DAPAT family
JRI60_22680	COG0018	arginyl-trna synthetase
JRI60_22685	COG2202	Pas domain
JRI60_22685	COG2205	protein histidine kinase activity
JRI60_22700	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JRI60_22710	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
JRI60_22715	COG0049	tRNA binding
JRI60_22720	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JRI60_22725	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JRI60_22730	COG0051	transcription antitermination factor activity, RNA binding
JRI60_22735	COG0088	Forms part of the polypeptide exit tunnel
JRI60_22740	COG0089	rRNA binding
JRI60_22745	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
JRI60_22750	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
JRI60_22755	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
JRI60_22760	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
JRI60_22765	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
JRI60_22770	COG0255	Belongs to the universal ribosomal protein uL29 family
JRI60_22775	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
JRI60_22780	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
JRI60_22785	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
JRI60_22795	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JRI60_22800	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
JRI60_22805	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
JRI60_22810	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
JRI60_22815	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
JRI60_22820	COG1841	ribosomal large subunit assembly
JRI60_22825	COG0200	Binds to the 23S rRNA
JRI60_22840	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
JRI60_22845	COG0257	Belongs to the bacterial ribosomal protein bL36 family
JRI60_22850	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JRI60_22855	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
JRI60_22860	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
JRI60_22875	COG0203	ribosomal protein L17
JRI60_22915	COG2313	pseudouridylate synthase activity
JRI60_22920	COG4251	negative regulation of phosphorylation
JRI60_22950	COG0741	lytic transglycosylase activity
JRI60_22975	COG3706	GGDEF domain
JRI60_22990	COG3209	COG3209 Rhs family protein
JRI60_23000	COG4372	Transposase
JRI60_23020	COG3209	COG3209 Rhs family protein
JRI60_23040	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
JRI60_23075	COG0515	serine threonine protein kinase
JRI60_23090	COG2706	6-phosphogluconolactonase activity
JRI60_23105	COG0583	DNA-binding transcription factor activity
JRI60_23120	COG5002	protein histidine kinase activity
JRI60_23140	COG2205	protein histidine kinase activity
JRI60_23185	COG1716	ATPase activity
JRI60_23195	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JRI60_23215	COG2205	protein histidine kinase activity
JRI60_23215	COG0784	Response regulator, receiver
JRI60_23220	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JRI60_23235	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
JRI60_23245	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
JRI60_23255	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
JRI60_23260	COG1546	Belongs to the CinA family
JRI60_23260	COG1058	Belongs to the CinA family
JRI60_23265	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JRI60_23275	COG0531	amino acid
JRI60_23280	COG0017	Asparaginyl-tRNA synthetase
JRI60_23295	COG0604	alcohol dehydrogenase
JRI60_23295	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_23295	COG3321	synthase
JRI60_23365	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JRI60_23400	COG0179	Fumarylacetoacetate (FAA) hydrolase
JRI60_23460	COG0217	transcriptional regulatory protein
JRI60_23475	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
JRI60_23500	COG4213	ABC transporter substrate-binding protein
JRI60_23510	COG4214	carbohydrate transport
JRI60_23525	COG1595	DNA-templated transcription, initiation
JRI60_23545	COG1263	PTS System
JRI60_23545	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JRI60_23545	COG2190	(PTS) system
JRI60_23550	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
JRI60_23550	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JRI60_23555	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
JRI60_23560	COG2188	Transcriptional regulator
JRI60_23565	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
JRI60_23570	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
JRI60_23575	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
JRI60_23600	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
JRI60_23625	COG0527	aspartate kinase activity
JRI60_23670	COG5002	protein histidine kinase activity
JRI60_23670	COG5000	phosphorelay sensor kinase activity
JRI60_23690	COG0443	Heat shock 70 kDa protein
JRI60_23725	COG0501	Belongs to the peptidase M48B family
JRI60_23735	COG2146	nitrite reductase [NAD(P)H] activity
JRI60_23735	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
JRI60_23755	COG1215	transferase activity, transferring glycosyl groups
JRI60_23815	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
JRI60_23820	COG3185	4-Hydroxyphenylpyruvate dioxygenase
JRI60_23830	COG1388	LysM domain
JRI60_23830	COG0791	NLP P60 protein
JRI60_23860	COG3321	synthase
JRI60_23860	COG0604	alcohol dehydrogenase
JRI60_23865	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JRI60_23870	COG0179	Fumarylacetoacetate (FAA) hydrolase
JRI60_23880	COG1309	transcriptional regulator
JRI60_23920	COG5002	protein histidine kinase activity
JRI60_23945	COG0617	tRNA 3'-terminal CCA addition
JRI60_23950	COG0827	DNA restriction-modification system
JRI60_23955	COG0482	sulfurtransferase activity
JRI60_23965	COG1482	cell wall glycoprotein biosynthetic process
JRI60_23990	COG0481	GTPase activity
JRI60_24005	COG0540	Belongs to the ATCase OTCase family
JRI60_24015	COG0505	Belongs to the CarA family
JRI60_24040	COG2124	cytochrome p450
JRI60_24055	COG3537	Alpha-1,2-mannosidase
JRI60_24105	COG2267	carboxylic ester hydrolase activity
JRI60_24120	COG0515	serine threonine protein kinase
JRI60_24145	COG2267	carboxylic ester hydrolase activity
JRI60_24155	COG3401	FG-GAP repeat protein
JRI60_24160	COG0577	efflux transmembrane transporter activity
JRI60_24160	COG1136	(ABC) transporter
JRI60_24175	COG0577	efflux transmembrane transporter activity
JRI60_24175	COG1136	(ABC) transporter
JRI60_24180	COG0577	efflux transmembrane transporter activity
JRI60_24180	COG1136	(ABC) transporter
JRI60_24195	COG4191	Histidine kinase
JRI60_24200	COG2204	response regulator
JRI60_24225	COG2909	trisaccharide binding
JRI60_24330	COG1022	Amp-dependent synthetase and ligase
JRI60_24335	COG0372	Belongs to the citrate synthase family
JRI60_24340	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
JRI60_24345	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
JRI60_24350	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
JRI60_24360	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
JRI60_24360	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
JRI60_24365	COG2226	methyltransferase
JRI60_24370	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
JRI60_24380	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
JRI60_24385	COG2267	carboxylic ester hydrolase activity
JRI60_24390	COG1575	Belongs to the MenA family. Type 1 subfamily
JRI60_24395	COG4948	Mandelate Racemase Muconate Lactonizing
JRI60_24435	COG4106	trans-aconitate 2-methyltransferase activity
JRI60_24440	COG0538	isocitrate dehydrogenase activity
JRI60_24450	COG1053	succinate dehydrogenase
JRI60_24455	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
JRI60_24460	COG0045	succinate-CoA ligase (ADP-forming) activity
JRI60_24465	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
JRI60_24510	COG4584	PFAM Integrase catalytic
JRI60_24520	COG1942	4-Oxalocrotonate Tautomerase
JRI60_24525	COG0583	DNA-binding transcription factor activity
JRI60_24530	COG2814	Major facilitator Superfamily
JRI60_24540	COG0633	Ferredoxin
JRI60_24550	COG1309	transcriptional regulator
JRI60_24570	COG2072	flavoprotein involved in K transport
JRI60_24590	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
JRI60_24590	COG1672	PFAM Archaeal ATPase
JRI60_24605	COG3590	peptidase
JRI60_24620	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
JRI60_24655	COG1819	glycosyl
JRI60_24665	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JRI60_24670	COG0820	rRNA (adenine-C2-)-methyltransferase activity
JRI60_24675	COG0228	four-way junction DNA binding
JRI60_24680	COG1837	Belongs to the UPF0109 family
JRI60_24685	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
JRI60_24690	COG0336	Belongs to the RNA methyltransferase TrmD family
JRI60_24695	COG0335	large ribosomal subunit rRNA binding
JRI60_24705	COG0792	nuclease activity
JRI60_24710	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
JRI60_24725	COG2204	response regulator
JRI60_24740	COG0728	peptidoglycan biosynthetic process
JRI60_24745	COG0539	negative regulation of cytoplasmic translation
JRI60_24790	COG2255	four-way junction helicase activity
JRI60_24805	COG0702	epimerase
JRI60_24825	COG4191	Histidine kinase
JRI60_24895	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
JRI60_24915	COG0515	serine threonine protein kinase
JRI60_24935	COG2205	protein histidine kinase activity
JRI60_24945	COG2124	cytochrome p450
JRI60_24950	COG0840	transmembrane signaling receptor activity
JRI60_24960	COG2124	cytochrome p450
JRI60_24965	COG3852	Histidine kinase
JRI60_24970	COG2304	oxidoreductase activity
JRI60_24990	COG4294	response to UV
JRI60_25000	COG1278	Cold shock
JRI60_25010	COG0545	Peptidyl-prolyl cis-trans isomerase
JRI60_25030	COG0628	permease
JRI60_25045	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JRI60_25055	COG0291	Belongs to the bacterial ribosomal protein bL35 family
JRI60_25060	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
JRI60_25065	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
JRI60_25070	COG0072	phenylalanine-tRNA ligase activity
JRI60_25075	COG0776	regulation of translation
JRI60_25125	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JRI60_25150	COG0582	viral genome integration into host DNA
JRI60_25180	COG1484	DNA-dependent DNA replication
JRI60_25185	COG4584	PFAM Integrase catalytic
JRI60_25190	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JRI60_25205	COG2080	2 iron, 2 sulfur cluster binding
JRI60_25210	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
JRI60_25215	COG1529	Aldehyde oxidase and xanthine dehydrogenase
JRI60_25220	COG4104	PAAR repeat-containing protein
JRI60_25235	COG1946	Acyl-CoA thioesterase
JRI60_25250	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JRI60_25255	COG1116	anion transmembrane transporter activity
JRI60_25280	COG1131	(ABC) transporter
JRI60_25305	COG0525	valine-tRNA ligase activity
JRI60_25360	COG2720	vancomycin resistance protein
JRI60_25430	COG0583	DNA-binding transcription factor activity
JRI60_25435	COG2249	NAD(P)H dehydrogenase (quinone) activity
JRI60_25440	COG0583	DNA-binding transcription factor activity
JRI60_25450	COG0583	DNA-binding transcription factor activity
JRI60_25485	COG3848	Pyruvate phosphate dikinase
JRI60_25485	COG0574	Belongs to the PEP-utilizing enzyme family
JRI60_25495	COG0726	polysaccharide deacetylase
JRI60_25535	COG0025	NhaP-type Na H and K H
JRI60_25555	COG1505	serine-type exopeptidase activity
JRI60_25600	COG0477	Major facilitator Superfamily
JRI60_25620	COG4771	TonB-dependent receptor
JRI60_25660	COG0513	Belongs to the DEAD box helicase family
JRI60_25665	COG3158	transport of potassium into the cell
JRI60_25670	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_25690	COG5002	protein histidine kinase activity
JRI60_25695	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
JRI60_25700	COG0745	RESPONSE REGULATOR receiver
JRI60_25705	COG1902	pentaerythritol trinitrate reductase activity
JRI60_25710	COG2272	Belongs to the type-B carboxylesterase lipase family
JRI60_25730	COG0753	catalase activity
JRI60_25775	COG4266	Belongs to the allantoicase family
JRI60_25780	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
JRI60_25785	COG2072	flavoprotein involved in K transport
JRI60_25790	COG2267	carboxylic ester hydrolase activity
JRI60_25800	COG3537	Alpha-1,2-mannosidase
JRI60_25805	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
JRI60_25810	COG1131	(ABC) transporter
JRI60_25845	COG1047	Peptidyl-prolyl cis-trans
JRI60_25850	COG1671	Belongs to the UPF0178 family
JRI60_25885	COG3459	Glycosyltransferase 36 associated
JRI60_25895	COG0366	Alpha amylase catalytic
JRI60_25905	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
JRI60_25910	COG1529	Aldehyde oxidase and xanthine dehydrogenase
JRI60_25915	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
JRI60_25920	COG2080	2 iron, 2 sulfur cluster binding
JRI60_25930	COG0515	serine threonine protein kinase
JRI60_25950	COG0626	cystathionine gamma-synthase activity
JRI60_25970	COG1672	PFAM Archaeal ATPase
JRI60_25970	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
JRI60_25985	COG2205	protein histidine kinase activity
JRI60_25990	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
JRI60_26000	COG0366	Alpha amylase catalytic
JRI60_26005	COG0366	Alpha amylase catalytic
JRI60_26055	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JRI60_26070	COG2136	Putative SAM-dependent methyltransferase
JRI60_26070	COG2521	methyltransferase
JRI60_26095	COG2197	response regulator
JRI60_26125	COG5002	protein histidine kinase activity
JRI60_26130	COG2124	cytochrome p450
JRI60_26135	COG0612	Peptidase, M16
JRI60_26145	COG0564	pseudouridine synthase activity
JRI60_26155	COG2814	Major facilitator Superfamily
JRI60_26170	COG0515	serine threonine protein kinase
JRI60_26185	COG0750	zinc metalloprotease
JRI60_26205	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JRI60_26215	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
JRI60_26250	COG0688	phosphatidylethanolamine metabolic process
JRI60_26305	COG0515	serine threonine protein kinase
JRI60_26310	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
JRI60_26315	COG0300	oxidoreductase activity
JRI60_26320	COG0745	RESPONSE REGULATOR receiver
JRI60_26345	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JRI60_26345	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JRI60_26365	COG0142	geranyltranstransferase activity
JRI60_26370	COG1830	Aldolase
JRI60_26385	COG0456	acetyltransferase
JRI60_26390	COG0156	8-amino-7-oxononanoate synthase activity
JRI60_26410	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
JRI60_26410	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
JRI60_26420	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
JRI60_26425	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JRI60_26440	COG2204	response regulator
JRI60_26460	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JRI60_26460	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JRI60_26465	COG2223	nitrite transmembrane transporter activity
JRI60_26485	COG0318	PFAM AMP-dependent synthetase and ligase
JRI60_26485	COG0204	Acyl-transferase
JRI60_26495	COG1070	Carbohydrate kinase
JRI60_26500	COG0246	Mannitol dehydrogenase
JRI60_26515	COG4209	transmembrane transport
JRI60_26525	COG2124	cytochrome p450
JRI60_26540	COG0288	reversible hydration of carbon dioxide
JRI60_26555	COG0784	Response regulator, receiver
JRI60_26555	COG2205	protein histidine kinase activity
JRI60_26560	COG0457	Tetratricopeptide repeat
JRI60_26575	COG1024	Enoyl-CoA hydratase
JRI60_26595	COG1131	(ABC) transporter
JRI60_26650	COG0657	acetylesterase activity
JRI60_26655	COG2202	Pas domain
JRI60_26655	COG2205	protein histidine kinase activity
JRI60_26670	COG0583	DNA-binding transcription factor activity
JRI60_26685	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JRI60_26700	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_26715	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JRI60_26720	COG2124	cytochrome p450
JRI60_26725	COG2124	cytochrome p450
JRI60_26730	COG1309	transcriptional regulator
JRI60_26795	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JRI60_26800	COG1960	acyl-CoA dehydrogenase activity
JRI60_26815	COG0571	ribonuclease III activity
JRI60_26825	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
JRI60_26830	COG1160	GTP binding
JRI60_26845	COG0494	nUDIX hydrolase
JRI60_26870	COG3179	chitinase
JRI60_26960	COG0519	Catalyzes the synthesis of GMP from XMP
JRI60_26960	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JRI60_26970	COG0516	GMP reductase activity
JRI60_26970	COG0517	IMP dehydrogenase activity
JRI60_26975	COG0443	Heat shock 70 kDa protein
JRI60_26980	COG0586	Pfam SNARE associated Golgi protein
JRI60_26990	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
JRI60_26995	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JRI60_27025	COG0720	synthase
JRI60_27030	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JRI60_27035	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
JRI60_27040	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
JRI60_27045	COG0183	Belongs to the thiolase family
JRI60_27060	COG1960	acyl-CoA dehydrogenase activity
JRI60_27070	COG1960	acyl-CoA dehydrogenase activity
JRI60_27075	COG1024	Enoyl-CoA hydratase
JRI60_27080	COG1250	3-hydroxyacyl-CoA dehydrogenase
JRI60_27095	COG0489	protein tyrosine kinase activity
JRI60_27120	COG0515	serine threonine protein kinase
JRI60_27180	COG4221	oxidoreductase activity
JRI60_27185	COG0339	signal peptide processing
JRI60_27215	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JRI60_27220	COG0667	Aldo Keto reductase
JRI60_27225	COG0519	Catalyzes the synthesis of GMP from XMP
JRI60_27270	COG2205	protein histidine kinase activity
JRI60_27275	COG0745	RESPONSE REGULATOR receiver
JRI60_27310	COG0604	alcohol dehydrogenase
JRI60_27310	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_27310	COG3321	synthase
JRI60_27325	COG1272	protein, Hemolysin III
JRI60_27380	COG0542	response to heat
JRI60_27390	COG2124	cytochrome p450
JRI60_27405	COG2124	cytochrome p450
JRI60_27415	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_27430	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_27460	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JRI60_27470	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_27480	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JRI60_27490	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JRI60_27495	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JRI60_27505	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_27520	COG1012	belongs to the aldehyde dehydrogenase family
JRI60_27520	COG2030	dehydratase
JRI60_27525	COG0430	RNA-3'-phosphate cyclase activity
JRI60_27540	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JRI60_27550	COG1187	pseudouridine synthase activity
JRI60_27555	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
JRI60_27560	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
JRI60_27595	COG4974	Belongs to the 'phage' integrase family
JRI60_27600	COG0009	L-threonylcarbamoyladenylate synthase
JRI60_27605	COG0475	glutathione-regulated potassium exporter activity
JRI60_27605	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
JRI60_27630	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
JRI60_27670	COG0515	serine threonine protein kinase
JRI60_27680	COG2433	Pfam Transposase IS66
JRI60_27735	COG2433	Pfam Transposase IS66
JRI60_27755	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
JRI60_27755	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
JRI60_27760	COG0860	N-Acetylmuramoyl-L-alanine amidase
JRI60_27780	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JRI60_27825	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JRI60_27830	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
JRI60_27840	COG0747	negative chemotaxis
JRI60_27845	COG0601	transmembrane transport
JRI60_27850	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JRI60_27855	COG0444	Belongs to the ABC transporter superfamily
JRI60_27860	COG4608	Belongs to the ABC transporter superfamily
JRI60_27865	COG1472	Belongs to the glycosyl hydrolase 3 family
JRI60_27890	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JRI60_27895	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JRI60_27910	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JRI60_27915	COG1126	abc transporter atp-binding protein
JRI60_27920	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
JRI60_27930	COG3507	Belongs to the glycosyl hydrolase 43 family
JRI60_27930	COG2382	esterase
JRI60_27930	COG3693	PFAM glycoside hydrolase, family 10
JRI60_28010	COG2815	serine threonine protein kinase
JRI60_28010	COG0515	serine threonine protein kinase
JRI60_28025	COG0585	pseudouridine synthase activity
JRI60_28030	COG1595	DNA-templated transcription, initiation
JRI60_28060	COG0300	oxidoreductase activity
JRI60_28090	COG0318	PFAM AMP-dependent synthetase and ligase
JRI60_28090	COG0204	Acyl-transferase
JRI60_28095	COG0708	Exodeoxyribonuclease III
JRI60_28105	COG0667	Aldo Keto reductase
JRI60_28115	COG4191	Histidine kinase
JRI60_28135	COG1960	acyl-CoA dehydrogenase activity
JRI60_28140	COG1073	alpha beta
JRI60_28195	COG2267	carboxylic ester hydrolase activity
JRI60_28220	COG0488	(ABC) transporter
JRI60_28330	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JRI60_28355	COG0583	DNA-binding transcription factor activity
JRI60_28385	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
JRI60_28400	COG0463	Glycosyl transferase, family 2
JRI60_28490	COG0667	Aldo Keto reductase
JRI60_28500	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JRI60_28515	COG2815	serine threonine protein kinase
JRI60_28515	COG0515	serine threonine protein kinase
JRI60_28540	COG2124	cytochrome p450
JRI60_28550	COG2070	2-Nitropropane dioxygenase
JRI60_28550	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
JRI60_28555	COG3321	synthase
JRI60_28560	COG1024	Enoyl-CoA hydratase
JRI60_28565	COG1024	Enoyl-CoA hydratase
JRI60_28570	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JRI60_28575	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JRI60_28580	COG3425	synthase
JRI60_28585	COG4221	oxidoreductase activity
JRI60_28585	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JRI60_28585	COG3321	synthase
JRI60_28585	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_28595	COG4221	oxidoreductase activity
JRI60_28595	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JRI60_28595	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_28595	COG3321	synthase
JRI60_28600	COG4221	oxidoreductase activity
JRI60_28600	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JRI60_28600	COG3321	synthase
JRI60_28600	COG0300	oxidoreductase activity
JRI60_28610	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
JRI60_28615	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
JRI60_28620	COG1438	arginine binding
JRI60_28625	COG0165	Argininosuccinate lyase
JRI60_28630	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JRI60_28635	COG2027	D-alanyl-D-alanine carboxypeptidase
JRI60_28640	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JRI60_28650	COG0436	Aminotransferase
JRI60_28655	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
JRI60_28660	COG0742	ribosomal rna small subunit methyltransferase
JRI60_28670	COG0004	ammonium transporteR
JRI60_28690	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JRI60_28695	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
JRI60_28705	COG2311	Membrane
JRI60_28745	COG0726	polysaccharide deacetylase
JRI60_28785	COG2204	response regulator
JRI60_28795	COG1217	gtp-binding protein TYPA
JRI60_28800	COG2814	Major facilitator Superfamily
JRI60_28840	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
JRI60_28850	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
JRI60_28865	COG5002	protein histidine kinase activity
JRI60_28945	COG0583	DNA-binding transcription factor activity
JRI60_28950	COG0527	aspartate kinase activity
JRI60_28960	COG1830	Aldolase
JRI60_28975	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JRI60_28990	COG1764	response to oxidative stress
JRI60_29000	COG2133	pyrroloquinoline quinone binding
JRI60_29005	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JRI60_29050	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
JRI60_29090	COG1846	Transcriptional regulator
JRI60_29105	COG1309	transcriptional regulator
JRI60_29110	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_29115	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
JRI60_29145	COG0739	heme binding
JRI60_29145	COG0741	lytic transglycosylase activity
JRI60_29145	COG1196	nuclear chromosome segregation
JRI60_29160	COG0714	Associated with various cellular activities
JRI60_29175	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JRI60_29180	COG1297	OPT oligopeptide transporter protein
JRI60_29215	COG0564	pseudouridine synthase activity
JRI60_29250	COG0741	lytic transglycosylase activity
JRI60_29255	COG4191	Histidine kinase
JRI60_29280	COG4681	YaeQ
JRI60_29305	COG0815	Transfers the fatty acyl group on membrane lipoproteins
JRI60_29315	COG0488	(ABC) transporter
JRI60_29330	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
JRI60_29335	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JRI60_29340	COG0825	malonyl-CoA metabolic process
JRI60_29390	COG0443	Heat shock 70 kDa protein
JRI60_29415	COG0101	tRNA pseudouridine synthase activity
JRI60_29430	COG1606	tRNA processing
JRI60_29435	COG2046	Belongs to the sulfate adenylyltransferase family
JRI60_29435	COG0529	Catalyzes the synthesis of activated sulfate
JRI60_29455	COG4585	Histidine kinase
JRI60_29490	COG1309	transcriptional regulator
JRI60_29530	COG2204	response regulator
JRI60_29655	COG1181	Belongs to the D-alanine--D-alanine ligase family
JRI60_29670	COG0113	porphobilinogen synthase activity
JRI60_29680	COG1131	(ABC) transporter
JRI60_29695	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
JRI60_29760	COG0686	Belongs to the AlaDH PNT family
JRI60_29765	COG1595	DNA-templated transcription, initiation
JRI60_29785	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
JRI60_29790	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
JRI60_29790	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
JRI60_29855	COG0572	uridine kinase
JRI60_29925	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JRI60_29940	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JRI60_29950	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JRI60_29960	COG0577	efflux transmembrane transporter activity
JRI60_29960	COG1136	(ABC) transporter
JRI60_29965	COG1136	(ABC) transporter
JRI60_29985	COG0542	response to heat
JRI60_30070	COG0737	Belongs to the 5'-nucleotidase family
JRI60_30110	COG0583	DNA-binding transcription factor activity
JRI60_30125	COG2815	serine threonine protein kinase
JRI60_30125	COG0515	serine threonine protein kinase
JRI60_30135	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JRI60_30145	COG3876	Protein conserved in bacteria
JRI60_30160	COG1193	negative regulation of DNA recombination
JRI60_30175	COG4447	cellulose binding
JRI60_30175	COG4733	cellulase activity
JRI60_30180	COG5297	Belongs to the glycosyl hydrolase family 6
JRI60_30180	COG4733	cellulase activity
JRI60_30185	COG3842	ATPase activity
JRI60_30195	COG1175	transmembrane transport
JRI60_30200	COG1653	transport
JRI60_30205	COG2723	6-phospho-beta-galactosidase activity
JRI60_30210	COG1609	Transcriptional regulator
JRI60_30230	COG2205	protein histidine kinase activity
JRI60_30265	COG2897	thiosulfate sulfurtransferase activity
JRI60_30270	COG0564	pseudouridine synthase activity
JRI60_30280	COG0557	exoribonuclease II activity
JRI60_30290	COG0303	'Molybdopterin
JRI60_30295	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JRI60_30295	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JRI60_30320	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
JRI60_30330	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JRI60_30350	COG0557	exoribonuclease II activity
JRI60_30360	COG0140	phosphoribosyl-ATP diphosphatase activity
JRI60_30360	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
JRI60_30370	COG0107	imidazoleglycerol-phosphate synthase activity
JRI60_30375	COG0131	Imidazoleglycerol-phosphate dehydratase
JRI60_30380	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
JRI60_30385	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
JRI60_30395	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
JRI60_30400	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
JRI60_30410	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
JRI60_30420	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
JRI60_30440	COG2204	response regulator
JRI60_30445	COG4191	Histidine kinase
JRI60_30450	COG4566	intracellular signal transduction
JRI60_30450	COG0745	RESPONSE REGULATOR receiver
JRI60_30455	COG2205	protein histidine kinase activity
JRI60_30505	COG0189	ligase activity
JRI60_30505	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JRI60_30515	COG1695	Transcriptional regulator
JRI60_30535	COG2072	flavoprotein involved in K transport
JRI60_30545	COG0657	acetylesterase activity
JRI60_30550	COG0386	Belongs to the glutathione peroxidase family
JRI60_30635	COG0515	serine threonine protein kinase
JRI60_30645	COG0515	serine threonine protein kinase
JRI60_30645	COG2815	serine threonine protein kinase
JRI60_30680	COG2072	flavoprotein involved in K transport
JRI60_30685	COG1309	transcriptional regulator
JRI60_30690	COG0583	DNA-binding transcription factor activity
JRI60_30720	COG1335	isochorismatase
JRI60_30735	COG2124	cytochrome p450
JRI60_30740	COG1846	Transcriptional regulator
JRI60_30755	COG0583	DNA-binding transcription factor activity
JRI60_30760	COG0667	Aldo Keto reductase
JRI60_30765	COG1064	alcohol dehydrogenase
JRI60_30795	COG1064	alcohol dehydrogenase
JRI60_30820	COG0583	DNA-binding transcription factor activity
JRI60_30845	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
JRI60_30865	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JRI60_30885	COG0494	nUDIX hydrolase
JRI60_30900	COG3088	subunit of a heme lyase
JRI60_30935	COG0391	Required for morphogenesis under gluconeogenic growth conditions
JRI60_30940	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JRI60_30945	COG0489	protein tyrosine kinase activity
JRI60_30970	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
JRI60_30990	COG4221	oxidoreductase activity
JRI60_30995	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JRI60_31010	COG0784	Response regulator, receiver
JRI60_31010	COG4191	Histidine kinase
JRI60_31025	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
JRI60_31035	COG0583	DNA-binding transcription factor activity
JRI60_31045	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
JRI60_31085	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
JRI60_31120	COG0534	Mate efflux family protein
JRI60_31150	COG1082	Xylose isomerase domain protein TIM barrel
JRI60_31205	COG1595	DNA-templated transcription, initiation
JRI60_31235	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JRI60_31240	COG3852	Histidine kinase
JRI60_31255	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JRI60_31255	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
JRI60_31260	COG2204	response regulator
JRI60_31265	COG3706	GGDEF domain
JRI60_31295	COG1131	(ABC) transporter
JRI60_31300	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JRI60_31300	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
JRI60_31355	COG1960	acyl-CoA dehydrogenase activity
JRI60_31360	COG1024	Enoyl-CoA hydratase
JRI60_31360	COG1250	3-hydroxyacyl-CoA dehydrogenase
JRI60_31365	COG0183	Belongs to the thiolase family
JRI60_31390	COG0443	Heat shock 70 kDa protein
JRI60_31405	COG2921	Belongs to the UPF0250 family
JRI60_31410	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
JRI60_31415	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JRI60_31430	COG0583	DNA-binding transcription factor activity
JRI60_31435	COG0604	alcohol dehydrogenase
JRI60_31435	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_31435	COG3321	synthase
JRI60_31460	COG2226	methyltransferase
JRI60_31465	COG5002	protein histidine kinase activity
JRI60_31475	COG3384	dioxygenase
JRI60_31480	COG0583	DNA-binding transcription factor activity
JRI60_31485	COG2198	Histidine kinase
JRI60_31485	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JRI60_31485	COG0784	Response regulator, receiver
JRI60_31485	COG2205	protein histidine kinase activity
JRI60_31490	COG1879	ABC-type sugar transport system periplasmic component
JRI60_31505	COG4104	PAAR repeat-containing protein
JRI60_31520	COG0457	Tetratricopeptide repeat
JRI60_31525	COG0436	Aminotransferase
JRI60_31545	COG4191	Histidine kinase
JRI60_31550	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JRI60_31555	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JRI60_31565	COG0175	sulfate reduction
JRI60_31570	COG1648	precorrin-2 dehydrogenase activity
JRI60_31570	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
JRI60_31580	COG0175	sulfate reduction
JRI60_31590	COG3217	Mosc domain protein beta barrel domain protein
JRI60_31590	COG0633	Ferredoxin
JRI60_31595	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
JRI60_31595	COG1672	PFAM Archaeal ATPase
JRI60_31600	COG1295	ribonuclease BN
JRI60_31600	COG1959	2 iron, 2 sulfur cluster binding
JRI60_31615	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JRI60_31620	COG0006	proline dipeptidase activity
JRI60_31625	COG3227	Zinc metalloprotease (Elastase)
JRI60_31640	COG5002	protein histidine kinase activity
JRI60_31645	COG0745	RESPONSE REGULATOR receiver
JRI60_31685	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
JRI60_31695	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JRI60_31730	COG2197	response regulator
JRI60_31735	COG0071	Belongs to the small heat shock protein (HSP20) family
JRI60_31800	COG1131	(ABC) transporter
JRI60_31820	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
JRI60_31840	COG1529	Aldehyde oxidase and xanthine dehydrogenase
JRI60_31855	COG3321	synthase
JRI60_31855	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_31855	COG4221	oxidoreductase activity
JRI60_31855	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JRI60_31860	COG3852	Histidine kinase
JRI60_31870	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
JRI60_31880	COG0484	heat shock protein binding
JRI60_31885	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JRI60_31895	COG1872	DUF167
JRI60_31920	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JRI60_31920	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JRI60_31935	COG1450	Type ii and iii secretion system protein
JRI60_31960	COG0751	glycine-tRNA ligase activity
JRI60_31965	COG0752	glycyl-tRNA synthetase alpha subunit
JRI60_31980	COG1381	Involved in DNA repair and RecF pathway recombination
JRI60_32015	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JRI60_32020	COG0085	RNA polymerase activity
JRI60_32025	COG0222	ribosome binding
JRI60_32030	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
JRI60_32035	COG0081	regulation of translation
JRI60_32040	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
JRI60_32060	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JRI60_32065	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JRI60_32090	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JRI60_32125	COG1643	Atp-dependent helicase
JRI60_32185	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JRI60_32185	COG0047	phosphoribosylformylglycinamidine synthase activity
JRI60_32195	COG0243	molybdopterin cofactor binding
JRI60_32215	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
JRI60_32340	COG1484	DNA-dependent DNA replication
JRI60_32345	COG4584	PFAM Integrase catalytic
JRI60_32360	COG0392	lysyltransferase activity
JRI60_32360	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
JRI60_32370	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JRI60_32380	COG2247	cell wall binding repeat
JRI60_32380	COG2385	sporulation resulting in formation of a cellular spore
JRI60_32390	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JRI60_32425	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JRI60_32425	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JRI60_32430	COG0509	glycine decarboxylation via glycine cleavage system
JRI60_32440	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
JRI60_32450	COG0596	Alpha beta hydrolase
JRI60_32460	COG4771	TonB-dependent receptor
JRI60_32470	COG1472	Belongs to the glycosyl hydrolase 3 family
JRI60_32505	COG1129	ABC transporter
JRI60_32520	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
JRI60_32525	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
JRI60_32530	COG0626	cystathionine gamma-synthase activity
JRI60_32535	COG0626	cystathionine gamma-synthase activity
JRI60_32540	COG0527	aspartate kinase activity
JRI60_32540	COG0460	homoserine dehydrogenase
JRI60_32555	COG2840	Smr protein MutS2
JRI60_32565	COG0167	dihydroorotate dehydrogenase activity
JRI60_32575	COG0297	glycogen (starch) synthase activity
JRI60_32590	COG0218	Necessary for normal cell division and for the maintenance of normal septation
JRI60_32605	COG0237	dephospho-CoA kinase activity
JRI60_32630	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
JRI60_32635	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
JRI60_32695	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
JRI60_32720	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JRI60_32740	COG1496	oxidoreductase activity
JRI60_32765	COG1543	Belongs to the glycosyl hydrolase 57 family
JRI60_32780	COG0745	RESPONSE REGULATOR receiver
JRI60_32780	COG1196	nuclear chromosome segregation
JRI60_32790	COG0542	response to heat
JRI60_32795	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
JRI60_32810	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
JRI60_32835	COG0515	serine threonine protein kinase
JRI60_32855	COG1692	metallophosphoesterase
JRI60_32860	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JRI60_32865	COG5002	protein histidine kinase activity
JRI60_32870	COG1940	carbohydrate kinase activity
JRI60_32875	COG1129	ABC transporter
JRI60_32880	COG1172	Belongs to the binding-protein-dependent transport system permease family
JRI60_32885	COG1879	ABC-type sugar transport system periplasmic component
JRI60_32895	COG0673	inositol 2-dehydrogenase activity
JRI60_32915	COG1408	metallophosphoesterase
JRI60_32920	COG0427	acetyl-CoA hydrolase
JRI60_32925	COG2373	Large extracellular alpha-helical protein
JRI60_32930	COG2135	peptidase activity
JRI60_32940	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
JRI60_32955	COG0515	serine threonine protein kinase
JRI60_32955	COG2815	serine threonine protein kinase
JRI60_32960	COG1960	acyl-CoA dehydrogenase activity
JRI60_32985	COG5002	protein histidine kinase activity
JRI60_32995	COG0604	alcohol dehydrogenase
JRI60_32995	COG3321	synthase
JRI60_33005	COG0604	alcohol dehydrogenase
JRI60_33005	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_33005	COG3321	synthase
JRI60_33010	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JRI60_33020	COG0745	RESPONSE REGULATOR receiver
JRI60_33030	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JRI60_33050	COG0277	FAD linked oxidase domain protein
JRI60_33055	COG0302	gtp cyclohydrolase
JRI60_33085	COG1121	(ABC) transporter
JRI60_33090	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JRI60_33095	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
JRI60_33100	COG0745	RESPONSE REGULATOR receiver
JRI60_33105	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_33110	COG1335	isochorismatase
JRI60_33155	COG0670	Belongs to the BI1 family
JRI60_33165	COG3411	Ferredoxin
JRI60_33170	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JRI60_33190	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JRI60_33195	COG0297	glycogen (starch) synthase activity
JRI60_33200	COG0438	transferase activity, transferring glycosyl groups
JRI60_33220	COG0322	excinuclease ABC activity
JRI60_33230	COG0515	serine threonine protein kinase
JRI60_33240	COG1396	sequence-specific DNA binding
JRI60_33255	COG0795	lipopolysaccharide-transporting ATPase activity
JRI60_33260	COG0151	Belongs to the GarS family
JRI60_33270	COG0138	bifunctional purine biosynthesis protein purh
JRI60_33275	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JRI60_33290	COG0515	serine threonine protein kinase
JRI60_33320	COG1183	phosphatidylcholine synthase activity
JRI60_33335	COG0351	phosphomethylpyrimidine kinase
JRI60_33340	COG0534	Mate efflux family protein
JRI60_33345	COG4191	Histidine kinase
JRI60_33360	COG0457	Tetratricopeptide repeat
JRI60_33360	COG0515	serine threonine protein kinase
JRI60_33370	COG2304	oxidoreductase activity
JRI60_33385	COG2890	protein-(glutamine-N5) methyltransferase activity
JRI60_33395	COG1793	dna ligase
JRI60_33425	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
JRI60_33435	COG3507	Belongs to the glycosyl hydrolase 43 family
JRI60_33440	COG1879	ABC-type sugar transport system periplasmic component
JRI60_33445	COG1129	ABC transporter
JRI60_33450	COG1172	Belongs to the binding-protein-dependent transport system permease family
JRI60_33455	COG1172	Belongs to the binding-protein-dependent transport system permease family
JRI60_33480	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
JRI60_33530	COG2433	Pfam Transposase IS66
JRI60_33575	COG0515	serine threonine protein kinase
JRI60_33620	COG4974	Belongs to the 'phage' integrase family
JRI60_33635	COG0149	triose-phosphate isomerase activity
JRI60_33640	COG0126	phosphoglycerate kinase activity
JRI60_33655	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
JRI60_33665	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
JRI60_33675	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
JRI60_33695	COG0084	hydrolase, TatD family'
JRI60_33705	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JRI60_33705	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JRI60_33720	COG1278	Cold shock
JRI60_33725	COG0626	cystathionine gamma-synthase activity
JRI60_33730	COG1522	sequence-specific DNA binding
JRI60_33755	COG3850	Histidine kinase
JRI60_33755	COG4999	Histidine kinase
JRI60_33755	COG3437	response regulator, receiver
JRI60_33755	COG2205	protein histidine kinase activity
JRI60_33760	COG0521	Mo-molybdopterin cofactor biosynthetic process
JRI60_33770	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
JRI60_33770	COG1796	DNA polymerase
JRI60_33790	COG0443	Heat shock 70 kDa protein
JRI60_33795	COG0484	heat shock protein binding
JRI60_33810	COG1166	arginine decarboxylase activity
JRI60_33815	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
JRI60_33815	COG2755	lipolytic protein G-D-S-L family
JRI60_33840	COG1752	Esterase of the alpha-beta hydrolase superfamily
JRI60_33860	COG1899	peptidyl-lysine modification to peptidyl-hypusine
JRI60_33870	COG1959	2 iron, 2 sulfur cluster binding
JRI60_33875	COG0613	PHP domain protein
JRI60_33880	COG2124	cytochrome p450
JRI60_33890	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JRI60_33895	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JRI60_33905	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JRI60_33910	COG0649	NAD binding
JRI60_33915	COG1034	ATP synthesis coupled electron transport
JRI60_33920	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
JRI60_33925	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JRI60_33985	COG0739	heme binding
JRI60_33990	COG3246	L-lysine catabolic process to acetate
JRI60_33995	COG1024	Enoyl-CoA hydratase
JRI60_34000	COG1309	transcriptional regulator
JRI60_34010	COG1396	sequence-specific DNA binding
JRI60_34045	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
JRI60_34055	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JRI60_34060	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
JRI60_34065	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
JRI60_34070	COG1683	Conserved Protein
JRI60_34075	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
JRI60_34085	COG1309	transcriptional regulator
JRI60_34095	COG0227	Belongs to the bacterial ribosomal protein bL28 family
JRI60_34100	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
JRI60_34120	COG1473	amidohydrolase
JRI60_34130	COG1846	Transcriptional regulator
JRI60_34140	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
JRI60_34145	COG1100	Small GTP-binding protein
JRI60_34170	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
JRI60_34200	COG0625	glutathione transferase activity
JRI60_34225	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
JRI60_34260	COG0626	cystathionine gamma-synthase activity
JRI60_34265	COG2076	Multidrug Resistance protein
JRI60_34325	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JRI60_34345	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JRI60_34380	COG1760	l-serine dehydratase
JRI60_34430	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JRI60_34430	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
JRI60_34430	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JRI60_34435	COG1105	Belongs to the carbohydrate kinase PfkB family
JRI60_34440	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JRI60_34440	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
JRI60_34445	COG1609	Transcriptional regulator
JRI60_34455	COG3590	peptidase
JRI60_34510	COG3795	YCII-related domain
JRI60_34515	COG0564	pseudouridine synthase activity
JRI60_34525	COG2308	Evidence 4 Homologs of previously reported genes of
JRI60_34535	COG0121	glutamine amidotransferase
JRI60_34560	COG0596	Alpha beta hydrolase
JRI60_34590	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JRI60_34615	COG4221	oxidoreductase activity
JRI60_34635	COG0586	Pfam SNARE associated Golgi protein
JRI60_34655	COG0840	transmembrane signaling receptor activity
JRI60_34695	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JRI60_34730	COG3852	Histidine kinase
JRI60_34745	COG0508	dehydrogenase complex catalyzes the overall conversion of
JRI60_34750	COG0022	dehydrogenase e1 component
JRI60_34750	COG0508	dehydrogenase complex catalyzes the overall conversion of
JRI60_34755	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JRI60_34780	COG0737	Belongs to the 5'-nucleotidase family
JRI60_34805	COG0312	modulator of DNA gyrase
JRI60_34815	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JRI60_34830	COG0181	hydroxymethylbilane synthase activity
JRI60_34835	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
JRI60_34840	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JRI60_34850	COG3118	belongs to the thioredoxin family
JRI60_34860	COG2239	Acts as a magnesium transporter
JRI60_34870	COG0772	Belongs to the SEDS family
JRI60_34875	COG0768	penicillin binding
JRI60_34890	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JRI60_34895	COG5001	Diguanylate cyclase
JRI60_34900	COG0424	maF-like protein
JRI60_34945	COG0322	excinuclease ABC activity
JRI60_34950	COG0556	nucleotide-excision repair
JRI60_34960	COG0215	cysteine-tRNA ligase activity
JRI60_34965	COG1716	ATPase activity
JRI60_34975	COG1329	Transcriptional regulator
JRI60_34980	COG0658	competence protein
JRI60_34980	COG2333	competence protein COMEC
JRI60_35005	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
JRI60_35010	COG1074	ATP-dependent DNA helicase activity
JRI60_35040	COG0604	alcohol dehydrogenase
JRI60_35055	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JRI60_35060	COG4558	Periplasmic binding protein
JRI60_35070	COG2207	Transcriptional regulator
JRI60_35100	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JRI60_35120	COG2130	NADP-dependent
JRI60_35135	COG4584	PFAM Integrase catalytic
JRI60_35140	COG1484	DNA-dependent DNA replication
JRI60_35165	COG1819	glycosyl
JRI60_35230	COG0515	serine threonine protein kinase
JRI60_35245	COG0515	serine threonine protein kinase
JRI60_35245	COG2815	serine threonine protein kinase
JRI60_35260	COG5006	permease, DMT superfamily
JRI60_35275	COG3940	Belongs to the glycosyl hydrolase 43 family
JRI60_35315	COG4968	Prepilin-type N-terminal cleavage methylation domain
JRI60_35335	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JRI60_35335	COG2124	cytochrome p450
JRI60_35355	COG0183	Belongs to the thiolase family
JRI60_35360	COG0477	Major facilitator Superfamily
JRI60_35385	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JRI60_35390	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JRI60_35400	COG1472	Belongs to the glycosyl hydrolase 3 family
JRI60_35435	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JRI60_35440	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JRI60_35445	COG0784	Response regulator, receiver
JRI60_35445	COG2205	protein histidine kinase activity
JRI60_35460	COG0753	catalase activity
JRI60_35460	COG0693	protein deglycase activity
JRI60_35465	COG1657	PFAM Prenyltransferase squalene oxidase
JRI60_35470	COG2203	Gaf domain
JRI60_35470	COG0840	transmembrane signaling receptor activity
JRI60_35515	COG2204	response regulator
JRI60_35535	COG0659	secondary active sulfate transmembrane transporter activity
JRI60_35540	COG2205	protein histidine kinase activity
JRI60_35545	COG2204	response regulator
JRI60_35565	COG2205	protein histidine kinase activity
JRI60_35570	COG0745	RESPONSE REGULATOR receiver
JRI60_35600	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
JRI60_35635	COG0515	serine threonine protein kinase
JRI60_35635	COG2815	serine threonine protein kinase
JRI60_35655	COG5297	Belongs to the glycosyl hydrolase family 6
JRI60_35660	COG1349	DNA-binding transcription factor activity
JRI60_35665	COG0494	nUDIX hydrolase
JRI60_35675	COG0477	Major facilitator Superfamily
JRI60_35715	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JRI60_35770	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JRI60_35775	COG1278	Cold shock
JRI60_35780	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_35785	COG0495	leucyl-tRNA aminoacylation
JRI60_35825	COG2197	response regulator
JRI60_35915	COG3275	phosphorelay sensor kinase activity
JRI60_35920	COG3279	Response regulator of the LytR AlgR family
JRI60_35990	COG0848	biopolymer transport protein
JRI60_36000	COG0739	heme binding
JRI60_36000	COG0741	lytic transglycosylase activity
JRI60_36000	COG1196	nuclear chromosome segregation
JRI60_36035	COG0784	Response regulator, receiver
JRI60_36035	COG2205	protein histidine kinase activity
JRI60_36045	COG0596	Alpha beta hydrolase
JRI60_36065	COG0667	Aldo Keto reductase
JRI60_36130	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JRI60_36145	COG1690	Belongs to the RtcB family
JRI60_36150	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
JRI60_36155	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JRI60_36165	COG0254	rRNA binding
JRI60_36180	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
JRI60_36185	COG2201	protein-glutamate methylesterase activity
JRI60_36215	COG2885	chlorophyll binding
JRI60_36225	COG2205	protein histidine kinase activity
JRI60_36245	COG2204	response regulator
JRI60_36250	COG2259	Doxx family
JRI60_36255	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JRI60_36260	COG0517	IMP dehydrogenase activity
JRI60_36260	COG0516	GMP reductase activity
JRI60_36300	COG0708	Exodeoxyribonuclease III
JRI60_36325	COG5000	phosphorelay sensor kinase activity
JRI60_36350	COG4584	PFAM Integrase catalytic
JRI60_36355	COG1484	DNA-dependent DNA replication
JRI60_36395	COG0513	Belongs to the DEAD box helicase family
JRI60_36425	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JRI60_36435	COG2084	Dehydrogenase
JRI60_36475	COG3047	cAMP biosynthetic process
JRI60_36475	COG2885	chlorophyll binding
JRI60_36485	COG0585	pseudouridine synthase activity
JRI60_36495	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JRI60_36495	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
JRI60_36500	COG0252	asparaginase activity
JRI60_36590	COG1278	Cold shock
JRI60_36605	COG0745	RESPONSE REGULATOR receiver
JRI60_36610	COG2205	protein histidine kinase activity
JRI60_36625	COG1131	(ABC) transporter
JRI60_36630	COG0109	protoheme IX farnesyltransferase activity
JRI60_36655	COG0443	Heat shock 70 kDa protein
JRI60_36660	COG1126	abc transporter atp-binding protein
JRI60_36665	COG0765	amino acid transport
JRI60_36670	COG2208	phosphoserine phosphatase activity
JRI60_36675	COG0596	Alpha beta hydrolase
JRI60_36700	COG1752	Esterase of the alpha-beta hydrolase superfamily
JRI60_36710	COG1022	Amp-dependent synthetase and ligase
JRI60_36715	COG0596	Alpha beta hydrolase
JRI60_36725	COG0318	PFAM AMP-dependent synthetase and ligase
JRI60_36750	COG0475	glutathione-regulated potassium exporter activity
JRI60_36780	COG0318	PFAM AMP-dependent synthetase and ligase
JRI60_36800	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
JRI60_36815	COG0543	2 iron, 2 sulfur cluster binding
JRI60_36815	COG0493	'glutamate synthase
JRI60_36825	COG2062	phosphohistidine phosphatase, SixA
JRI60_36830	COG1965	Belongs to the frataxin family
JRI60_36840	COG0233	cytoplasmic translational termination
JRI60_36845	COG0528	UMP kinase activity
JRI60_36850	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
JRI60_36855	COG0052	Belongs to the universal ribosomal protein uS2 family
JRI60_36860	COG0653	protein targeting
JRI60_36865	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
JRI60_36875	COG0739	heme binding
JRI60_36880	COG0631	protein serine/threonine phosphatase activity
JRI60_36885	COG0497	DNA recombination
JRI60_36890	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JRI60_36895	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JRI60_36900	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JRI60_36910	COG1309	transcriptional regulator
JRI60_36915	COG2223	nitrite transmembrane transporter activity
JRI60_36920	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
JRI60_36930	COG0737	Belongs to the 5'-nucleotidase family
JRI60_36940	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JRI60_36945	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
JRI60_36955	COG5002	protein histidine kinase activity
JRI60_36960	COG3706	GGDEF domain
JRI60_36965	COG0463	Glycosyl transferase, family 2
JRI60_36970	COG3394	polysaccharide catabolic process
JRI60_36990	COG1024	Enoyl-CoA hydratase
JRI60_36990	COG1250	3-hydroxyacyl-CoA dehydrogenase
JRI60_36995	COG0183	Belongs to the thiolase family
JRI60_37010	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
JRI60_37050	COG4221	oxidoreductase activity
JRI60_37070	COG0456	acetyltransferase
JRI60_37080	COG2815	serine threonine protein kinase
JRI60_37080	COG0515	serine threonine protein kinase
JRI60_37120	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
JRI60_37125	COG0515	serine threonine protein kinase
JRI60_37135	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JRI60_37155	COG0515	serine threonine protein kinase
JRI60_37155	COG2815	serine threonine protein kinase
JRI60_37160	COG1262	PFAM Formylglycine-generating sulfatase enzyme
JRI60_37170	COG3852	Histidine kinase
JRI60_37175	COG2204	response regulator
JRI60_37245	COG0438	transferase activity, transferring glycosyl groups
JRI60_37255	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
JRI60_37275	COG0583	DNA-binding transcription factor activity
JRI60_37290	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JRI60_37305	COG0531	amino acid
JRI60_37375	COG2304	oxidoreductase activity
JRI60_37395	COG0546	phosphoglycolate phosphatase activity
JRI60_37400	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JRI60_37405	COG0596	Alpha beta hydrolase
JRI60_37415	COG4702	Belongs to the UPF0303 family
JRI60_37420	COG0300	oxidoreductase activity
JRI60_37440	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JRI60_37450	COG2010	Cytochrome c
JRI60_37460	COG3278	Belongs to the heme-copper respiratory oxidase family
JRI60_37495	COG1404	Belongs to the peptidase S8 family
JRI60_37505	COG0515	serine threonine protein kinase
JRI60_37510	COG4268	DNA restriction-modification system
JRI60_37515	COG1401	restriction endodeoxyribonuclease activity
JRI60_37540	COG0437	4 iron, 4 sulfur cluster binding
JRI60_37575	COG1858	cytochrome C peroxidase
JRI60_37600	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JRI60_37620	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
JRI60_37630	COG2234	aminopeptidase activity
JRI60_37650	COG0006	proline dipeptidase activity
JRI60_37660	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JRI60_37675	COG1621	beta-fructofuranosidase activity
JRI60_37710	COG1819	glycosyl
JRI60_37720	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
JRI60_37725	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
JRI60_37730	COG0271	Belongs to the BolA IbaG family
JRI60_37735	COG1678	Uncharacterized ACR, COG1678
JRI60_37740	COG4565	transcriptional regulatory protein
JRI60_37755	COG4166	transmembrane transport
JRI60_37765	COG1505	serine-type exopeptidase activity
JRI60_37775	COG0740	serine-type endopeptidase activity
JRI60_37780	COG0544	peptidyl-prolyl cis-trans isomerase activity
JRI60_37820	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JRI60_37825	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
JRI60_37830	COG0860	N-Acetylmuramoyl-L-alanine amidase
JRI60_37850	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JRI60_37855	COG2137	regulation of response to DNA damage stimulus
JRI60_37875	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
JRI60_37880	COG0210	DNA helicase
JRI60_37895	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
JRI60_37950	COG0084	hydrolase, TatD family'
JRI60_37955	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
JRI60_37975	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_38030	COG0646	methionine synthase
JRI60_38030	COG1410	methionine synthase
JRI60_38035	COG2226	methyltransferase
JRI60_38050	COG1832	CoA-binding protein
JRI60_38065	COG0515	serine threonine protein kinase
JRI60_38140	COG1063	alcohol dehydrogenase
JRI60_38145	COG1181	Belongs to the D-alanine--D-alanine ligase family
JRI60_38155	COG3425	synthase
JRI60_38175	COG1309	transcriptional regulator
JRI60_38185	COG0315	cyclic pyranopterin monophosphate synthase activity
JRI60_38195	COG0492	ferredoxin-NADP+ reductase activity
JRI60_38200	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JRI60_38205	COG5002	protein histidine kinase activity
JRI60_38210	COG0745	RESPONSE REGULATOR receiver
JRI60_38375	COG1335	isochorismatase
JRI60_38415	COG2022	thiamine diphosphate biosynthetic process
JRI60_38440	COG2124	cytochrome p450
JRI60_38455	COG1673	EVE domain
JRI60_38470	COG2205	protein histidine kinase activity
JRI60_38470	COG2202	Pas domain
JRI60_38490	COG0667	Aldo Keto reductase
JRI60_38495	COG2003	Belongs to the UPF0758 family
JRI60_38505	COG0514	ATP-dependent DNA helicase (RecQ)
JRI60_38535	COG0204	Acyl-transferase
JRI60_38550	COG0515	serine threonine protein kinase
JRI60_38550	COG2815	serine threonine protein kinase
JRI60_38575	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JRI60_38595	COG0590	tRNA wobble adenosine to inosine editing
JRI60_38620	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JRI60_38630	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
JRI60_38635	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
JRI60_38640	COG0515	serine threonine protein kinase
JRI60_38660	COG1100	Small GTP-binding protein
JRI60_38720	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JRI60_38725	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JRI60_38730	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JRI60_38735	COG1619	proteins homologs of microcin C7 resistance protein MccF
JRI60_38740	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JRI60_38740	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JRI60_38760	COG1404	Belongs to the peptidase S8 family
JRI60_38765	COG0464	growth
JRI60_38815	COG3781	membrane
JRI60_38825	COG0534	Mate efflux family protein
JRI60_38900	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JRI60_38900	COG3321	synthase
JRI60_38900	COG0300	oxidoreductase activity
JRI60_38900	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_38900	COG0318	PFAM AMP-dependent synthetase and ligase
JRI60_38935	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JRI60_38950	COG0656	L-ascorbic acid biosynthetic process
JRI60_38955	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JRI60_38965	COG0512	Glutamine amidotransferase of anthranilate synthase
JRI60_38975	COG2205	protein histidine kinase activity
JRI60_38980	COG1187	pseudouridine synthase activity
JRI60_39000	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JRI60_39025	COG0515	serine threonine protein kinase
JRI60_39055	COG2311	Membrane
JRI60_39060	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JRI60_39060	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
JRI60_39070	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JRI60_39095	COG3135	benzoate transporter
JRI60_39140	COG2205	protein histidine kinase activity
JRI60_39155	COG0318	PFAM AMP-dependent synthetase and ligase
JRI60_39160	COG2814	Major facilitator Superfamily
JRI60_39185	COG3854	ATPases associated with a variety of cellular activities
JRI60_39205	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JRI60_39210	COG1196	nuclear chromosome segregation
JRI60_39220	COG0741	lytic transglycosylase activity
JRI60_39220	COG0739	heme binding
JRI60_39220	COG1196	nuclear chromosome segregation
JRI60_39240	COG0450	alkyl hydroperoxide reductase
JRI60_39245	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JRI60_39250	COG0783	Belongs to the Dps family
JRI60_39260	COG1505	serine-type exopeptidase activity
JRI60_39265	COG3590	peptidase
JRI60_39290	COG1309	transcriptional regulator
JRI60_39295	COG3243	poly(R)-hydroxyalkanoic acid synthase
JRI60_39315	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JRI60_39325	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
JRI60_39345	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JRI60_39350	COG2010	Cytochrome c
JRI60_39355	COG3359	exonuclease
JRI60_39360	COG1205	dead DEAH box helicase
JRI60_39360	COG1111	helicase
JRI60_39365	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
JRI60_39390	COG0723	plastoquinol--plastocyanin reductase activity
JRI60_39390	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JRI60_39425	COG1131	(ABC) transporter
JRI60_39435	COG0009	L-threonylcarbamoyladenylate synthase
JRI60_39445	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
JRI60_39450	COG2967	ApaG domain
JRI60_39475	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JRI60_39495	COG0318	PFAM AMP-dependent synthetase and ligase
JRI60_39500	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JRI60_39510	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
JRI60_39525	COG5002	protein histidine kinase activity
JRI60_39530	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
JRI60_39575	COG0702	epimerase
JRI60_39595	COG0784	Response regulator, receiver
JRI60_39595	COG2205	protein histidine kinase activity
JRI60_39600	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
JRI60_39620	COG5002	protein histidine kinase activity
JRI60_39630	COG4251	negative regulation of phosphorylation
JRI60_39715	COG0189	ligase activity
JRI60_39725	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
JRI60_39830	COG2234	aminopeptidase activity
JRI60_39875	COG5183	chlorophyll binding
JRI60_39875	COG2133	pyrroloquinoline quinone binding
JRI60_39895	COG2267	carboxylic ester hydrolase activity
JRI60_39910	COG1072	(Pantothenic acid kinase))
JRI60_39975	COG0714	Associated with various cellular activities
JRI60_39985	COG3552	Protein containing von Willebrand factor type A (VWA) domain
JRI60_39990	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
JRI60_40010	COG5002	protein histidine kinase activity
JRI60_40040	COG0784	Response regulator, receiver
JRI60_40055	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JRI60_40060	COG1666	GTP binding
JRI60_40070	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JRI60_40110	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
JRI60_40115	COG0211	Belongs to the bacterial ribosomal protein bL27 family
JRI60_40120	COG0261	This protein binds to 23S rRNA in the presence of protein L20
JRI60_40140	COG4191	Histidine kinase
JRI60_40150	COG2205	protein histidine kinase activity
JRI60_40180	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JRI60_40185	COG0583	DNA-binding transcription factor activity
JRI60_40190	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_40205	COG3279	Response regulator of the LytR AlgR family
JRI60_40210	COG3275	phosphorelay sensor kinase activity
JRI60_40215	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JRI60_40220	COG0154	amidase activity
JRI60_40225	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JRI60_40260	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
JRI60_40260	COG0116	Belongs to the methyltransferase superfamily
JRI60_40265	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
JRI60_40340	COG1252	NADH dehydrogenase
JRI60_40345	COG0204	Acyl-transferase
JRI60_40365	COG1058	Belongs to the CinA family
JRI60_40365	COG1546	Belongs to the CinA family
JRI60_40370	COG1183	phosphatidylcholine synthase activity
JRI60_40385	COG0776	regulation of translation
JRI60_40390	COG0739	heme binding
JRI60_40400	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JRI60_40405	COG0242	peptide deformylase activity
JRI60_40415	COG0484	heat shock protein binding
JRI60_40420	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JRI60_40465	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
JRI60_40490	COG1215	transferase activity, transferring glycosyl groups
JRI60_40560	COG5002	protein histidine kinase activity
JRI60_40565	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
JRI60_40575	COG1960	acyl-CoA dehydrogenase activity
JRI60_40585	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_40605	COG0596	Alpha beta hydrolase
JRI60_40630	COG2205	protein histidine kinase activity
JRI60_40635	COG0515	serine threonine protein kinase
JRI60_40645	COG1454	alcohol dehydrogenase
JRI60_40650	COG0824	Thioesterase
JRI60_40690	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_40725	COG0515	serine threonine protein kinase
JRI60_40730	COG5002	protein histidine kinase activity
JRI60_40735	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JRI60_40740	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
JRI60_40745	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JRI60_40805	COG1366	Belongs to the anti-sigma-factor antagonist family
JRI60_40815	COG1366	Belongs to the anti-sigma-factor antagonist family
JRI60_40845	COG0667	Aldo Keto reductase
JRI60_40850	COG2204	response regulator
JRI60_40860	COG2183	response to ionizing radiation
JRI60_40880	COG1304	FMN binding
JRI60_40885	COG1115	amino acid carrier protein
JRI60_40890	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JRI60_40905	COG4948	Mandelate Racemase Muconate Lactonizing
JRI60_40935	COG1132	(ABC) transporter
JRI60_40950	COG0515	serine threonine protein kinase
JRI60_40960	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JRI60_40970	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
JRI60_40975	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JRI60_40985	COG0405	Gamma-glutamyltransferase
JRI60_41015	COG0788	formyltetrahydrofolate deformylase activity
JRI60_41080	COG0513	Belongs to the DEAD box helicase family
JRI60_41090	COG1741	Belongs to the pirin family
JRI60_41110	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
JRI60_41115	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JRI60_41125	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
JRI60_41150	COG0515	serine threonine protein kinase
JRI60_41155	COG1672	PFAM Archaeal ATPase
JRI60_41155	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
JRI60_41165	COG3850	Histidine kinase
JRI60_41165	COG5002	protein histidine kinase activity
JRI60_41170	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_41180	COG2070	2-Nitropropane dioxygenase
JRI60_41190	COG0583	DNA-binding transcription factor activity
JRI60_41205	COG0515	serine threonine protein kinase
JRI60_41205	COG2815	serine threonine protein kinase
JRI60_41215	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JRI60_41230	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_41235	COG0583	DNA-binding transcription factor activity
JRI60_41265	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JRI60_41270	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
JRI60_41295	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
JRI60_41305	COG1716	ATPase activity
JRI60_41325	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
JRI60_41340	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
JRI60_41350	COG5002	protein histidine kinase activity
JRI60_41355	COG0745	RESPONSE REGULATOR receiver
JRI60_41380	COG1228	amidohydrolase
JRI60_41405	COG1073	alpha beta
JRI60_41460	COG0402	S-adenosylhomocysteine deaminase activity
JRI60_41490	COG1007	ATP synthesis coupled electron transport
JRI60_41625	COG0730	response to heat
JRI60_41635	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JRI60_41650	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_41655	COG0596	Alpha beta hydrolase
JRI60_41660	COG1024	Enoyl-CoA hydratase
JRI60_41700	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
JRI60_41705	COG3852	Histidine kinase
JRI60_41710	COG3852	Histidine kinase
JRI60_41745	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
JRI60_41745	COG4651	solute:proton antiporter activity
JRI60_41770	COG0515	serine threonine protein kinase
JRI60_41775	COG0297	glycogen (starch) synthase activity
JRI60_41795	COG3275	phosphorelay sensor kinase activity
JRI60_41800	COG4585	Histidine kinase
JRI60_41805	COG0745	RESPONSE REGULATOR receiver
JRI60_41810	COG0784	Response regulator, receiver
JRI60_41810	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JRI60_41820	COG1484	DNA-dependent DNA replication
JRI60_41825	COG4584	PFAM Integrase catalytic
JRI60_41840	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JRI60_41865	COG2124	cytochrome p450
JRI60_41870	COG2124	cytochrome p450
JRI60_41890	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JRI60_41935	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_41940	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
JRI60_41955	COG4221	oxidoreductase activity
JRI60_41960	COG2207	Transcriptional regulator
JRI60_41985	COG0346	lactoylglutathione lyase activity
JRI60_41990	COG1940	carbohydrate kinase activity
JRI60_42005	COG1793	dna ligase
JRI60_42010	COG1201	RNA secondary structure unwinding
JRI60_42020	COG2124	cytochrome p450
JRI60_42025	COG3279	Response regulator of the LytR AlgR family
JRI60_42050	COG0644	oxidoreductase
JRI60_42065	COG0820	rRNA (adenine-C2-)-methyltransferase activity
JRI60_42075	COG0644	oxidoreductase
JRI60_42090	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JRI60_42110	COG5002	protein histidine kinase activity
JRI60_42115	COG0471	metal ion transport
JRI60_42115	COG3273	potassium ion transport
JRI60_42120	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
JRI60_42155	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JRI60_42155	COG4221	oxidoreductase activity
JRI60_42155	COG3321	synthase
JRI60_42155	COG0300	oxidoreductase activity
JRI60_42170	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JRI60_42175	COG1297	OPT oligopeptide transporter protein
JRI60_42180	COG4251	negative regulation of phosphorylation
JRI60_42185	COG0784	Response regulator, receiver
JRI60_42200	COG0436	Aminotransferase
JRI60_42210	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
JRI60_42215	COG0156	8-amino-7-oxononanoate synthase activity
JRI60_42220	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
JRI60_42230	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
JRI60_42285	COG5297	Belongs to the glycosyl hydrolase family 6
JRI60_42290	COG1876	peptidase activity
JRI60_42310	COG5464	transposase or invertase
JRI60_42315	COG3852	Histidine kinase
JRI60_42320	COG4251	negative regulation of phosphorylation
JRI60_42330	COG2205	protein histidine kinase activity
JRI60_42380	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
JRI60_42385	COG0471	metal ion transport
JRI60_42385	COG3273	potassium ion transport
JRI60_42390	COG0561	phosphatase activity
JRI60_42395	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JRI60_42400	COG1690	Belongs to the RtcB family
JRI60_42415	COG0205	6-phosphofructokinase activity
JRI60_42425	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
JRI60_42435	COG4191	Histidine kinase
JRI60_42465	COG5002	protein histidine kinase activity
JRI60_42475	COG2205	protein histidine kinase activity
JRI60_42505	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
JRI60_42525	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
JRI60_42555	COG0432	Pfam Uncharacterised protein family UPF0047
JRI60_42560	COG2204	response regulator
JRI60_42565	COG4251	negative regulation of phosphorylation
JRI60_42580	COG5001	Diguanylate cyclase
JRI60_42590	COG1262	PFAM Formylglycine-generating sulfatase enzyme
JRI60_42645	COG1024	Enoyl-CoA hydratase
JRI60_42655	COG2151	metal-sulfur cluster biosynthetic enzyme
JRI60_42660	COG0822	iron-sulfur transferase activity
JRI60_42670	COG0719	Fe-S assembly protein
JRI60_42675	COG0396	ATPase activity
JRI60_42680	COG0719	Fe-S assembly protein
JRI60_42685	COG1959	2 iron, 2 sulfur cluster binding
JRI60_42755	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JRI60_42765	COG0612	Peptidase, M16
JRI60_42795	COG2264	protein methyltransferase activity
JRI60_42820	COG1385	rRNA (uridine-N3-)-methyltransferase activity
JRI60_42830	COG1714	RDD family
JRI60_42840	COG4191	Histidine kinase
JRI60_42890	COG2204	response regulator
JRI60_42895	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_42925	COG2264	protein methyltransferase activity
JRI60_42935	COG2264	protein methyltransferase activity
JRI60_42970	COG0339	signal peptide processing
JRI60_43005	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JRI60_43015	COG0439	Biotin carboxylase
JRI60_43020	COG5016	pyruvate
JRI60_43020	COG0511	ligase activity, forming carbon-carbon bonds
JRI60_43025	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
JRI60_43025	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
JRI60_43045	COG0730	response to heat
JRI60_43055	COG0484	heat shock protein binding
JRI60_43070	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
JRI60_43075	COG0519	Catalyzes the synthesis of GMP from XMP
JRI60_43095	COG0564	pseudouridine synthase activity
JRI60_43110	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
JRI60_43115	COG1132	(ABC) transporter
JRI60_43125	COG0504	CTP synthase activity
JRI60_43130	COG2877	3-deoxy-8-phosphooctulonate synthase activity
JRI60_43135	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
JRI60_43145	COG0071	Belongs to the small heat shock protein (HSP20) family
JRI60_43170	COG0515	serine threonine protein kinase
JRI60_43170	COG2815	serine threonine protein kinase
JRI60_43190	COG0839	Belongs to the complex I subunit 6 family
JRI60_43195	COG0713	ATP synthesis coupled electron transport
JRI60_43200	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JRI60_43210	COG1007	ATP synthesis coupled electron transport
JRI60_43215	COG2204	response regulator
JRI60_43220	COG4191	Histidine kinase
JRI60_43230	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JRI60_43235	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
JRI60_43245	COG0629	single-stranded DNA binding
JRI60_43250	COG2027	D-alanyl-D-alanine carboxypeptidase
JRI60_43260	COG0747	negative chemotaxis
JRI60_43265	COG0601	transmembrane transport
JRI60_43270	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JRI60_43275	COG2153	protein acetylation
JRI60_43325	COG1309	transcriptional regulator
JRI60_43355	COG1490	D-aminoacyl-tRNA deacylase activity
JRI60_43365	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JRI60_43370	COG1472	Belongs to the glycosyl hydrolase 3 family
JRI60_43405	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
JRI60_43410	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JRI60_43435	COG2267	carboxylic ester hydrolase activity
JRI60_43465	COG1960	acyl-CoA dehydrogenase activity
JRI60_43520	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JRI60_43560	COG0745	RESPONSE REGULATOR receiver
JRI60_43575	COG1733	regulation of RNA biosynthetic process
JRI60_43650	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
JRI60_43655	COG0574	Belongs to the PEP-utilizing enzyme family
JRI60_43655	COG3848	Pyruvate phosphate dikinase
JRI60_43685	COG2133	pyrroloquinoline quinone binding
JRI60_43730	COG2259	Doxx family
JRI60_43735	COG0583	DNA-binding transcription factor activity
JRI60_43790	COG2205	protein histidine kinase activity
JRI60_43790	COG0784	Response regulator, receiver
JRI60_43835	COG2124	cytochrome p450
JRI60_43840	COG1309	transcriptional regulator
JRI60_43850	COG1408	metallophosphoesterase
JRI60_43885	COG0657	acetylesterase activity
JRI60_43895	COG0583	DNA-binding transcription factor activity
JRI60_43935	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_43970	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_43980	COG0438	transferase activity, transferring glycosyl groups
JRI60_43995	COG1137	ATPase activity
JRI60_44010	COG1560	Kdo2-lipid A biosynthetic process
JRI60_44015	COG3724	N-succinylarginine dihydrolase activity
JRI60_44075	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JRI60_44085	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
JRI60_44110	COG0366	Alpha amylase catalytic
JRI60_44110	COG1874	Beta-galactosidase
JRI60_44120	COG2124	cytochrome p450
JRI60_44155	COG0438	transferase activity, transferring glycosyl groups
JRI60_44165	COG0438	transferase activity, transferring glycosyl groups
JRI60_44180	COG0489	protein tyrosine kinase activity
JRI60_44210	COG1696	Membrane protein involved in D-alanine export
JRI60_44260	COG1999	signal sequence binding
JRI60_44300	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
JRI60_44310	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
JRI60_44360	COG2322	membrane
JRI60_44365	COG5002	protein histidine kinase activity
JRI60_44370	COG0784	Response regulator, receiver
JRI60_44375	COG4251	negative regulation of phosphorylation
JRI60_44385	COG1404	Belongs to the peptidase S8 family
JRI60_44390	COG3842	ATPase activity
JRI60_44395	COG3842	ATPase activity
JRI60_44405	COG0395	ABC-type sugar transport system, permease component
JRI60_44450	COG1201	RNA secondary structure unwinding
JRI60_44480	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
JRI60_44500	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JRI60_44530	COG2010	Cytochrome c
JRI60_44530	COG1529	Aldehyde oxidase and xanthine dehydrogenase
JRI60_44560	COG0420	3'-5' exonuclease activity
JRI60_44575	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_44630	COG4555	ABC transporter
JRI60_44635	COG1668	transmembrane transport
JRI60_44645	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JRI60_44650	COG0363	glucosamine-6-phosphate deaminase activity
JRI60_44655	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
JRI60_44670	COG1529	Aldehyde oxidase and xanthine dehydrogenase
JRI60_44670	COG2010	Cytochrome c
JRI60_44695	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JRI60_44715	COG2205	protein histidine kinase activity
JRI60_44720	COG4191	Histidine kinase
JRI60_44725	COG0217	transcriptional regulatory protein
JRI60_44730	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
JRI60_44735	COG3005	denitrification pathway
JRI60_44745	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
JRI60_44750	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
JRI60_44775	COG1876	peptidase activity
JRI60_44810	COG2815	serine threonine protein kinase
JRI60_44810	COG0515	serine threonine protein kinase
JRI60_44825	COG3425	synthase
JRI60_44860	COG0028	Belongs to the TPP enzyme family
JRI60_44905	COG1233	COG1233 Phytoene dehydrogenase and related
JRI60_44915	COG1562	ergosterol biosynthetic process
JRI60_44925	COG0142	geranyltranstransferase activity
JRI60_44935	COG1090	epimerase
JRI60_44940	COG1408	metallophosphoesterase
JRI60_44945	COG1309	transcriptional regulator
JRI60_45045	COG0783	Belongs to the Dps family
JRI60_45055	COG0625	glutathione transferase activity
JRI60_45060	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
JRI60_45065	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
JRI60_45080	COG0443	Heat shock 70 kDa protein
JRI60_45095	COG0242	peptide deformylase activity
JRI60_45110	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JRI60_45110	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JRI60_45150	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
JRI60_45155	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
JRI60_45170	COG1858	cytochrome C peroxidase
JRI60_45190	COG1522	sequence-specific DNA binding
JRI60_45195	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JRI60_45255	COG1876	peptidase activity
JRI60_45265	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JRI60_45280	COG0436	Aminotransferase
JRI60_45300	COG0826	peptidase U32
JRI60_45310	COG1605	Chorismate mutase
JRI60_45310	COG0287	Prephenate dehydrogenase
JRI60_45325	COG2376	Dihydroxyacetone kinase
JRI60_45330	COG2205	protein histidine kinase activity
JRI60_45335	COG1994	Peptidase M50
JRI60_45390	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JRI60_45420	COG5002	protein histidine kinase activity
JRI60_45425	COG0784	Response regulator, receiver
JRI60_45430	COG4251	negative regulation of phosphorylation
JRI60_45440	COG4772	TonB-dependent receptor
JRI60_45450	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JRI60_45455	COG1960	acyl-CoA dehydrogenase activity
JRI60_45465	COG4783	chaperone-mediated protein folding
JRI60_45475	COG3227	Zinc metalloprotease (Elastase)
JRI60_45495	COG0612	Peptidase, M16
JRI60_45500	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JRI60_45540	COG0583	DNA-binding transcription factor activity
JRI60_45545	COG1574	metal-dependent hydrolase with the TIM-barrel fold
JRI60_45555	COG0438	transferase activity, transferring glycosyl groups
JRI60_45565	COG0330	HflC and HflK could
JRI60_45605	COG4977	sequence-specific DNA binding
JRI60_45640	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
JRI60_45695	COG3107	peptidoglycan biosynthetic process
JRI60_45715	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JRI60_45725	COG0515	serine threonine protein kinase
JRI60_45730	COG2204	response regulator
JRI60_45740	COG3227	Zinc metalloprotease (Elastase)
JRI60_45750	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JRI60_45755	COG1472	Belongs to the glycosyl hydrolase 3 family
JRI60_45765	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JRI60_45770	COG0484	heat shock protein binding
JRI60_45780	COG1132	(ABC) transporter
JRI60_45815	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JRI60_45820	COG5002	protein histidine kinase activity
JRI60_45835	COG4999	Histidine kinase
JRI60_45835	COG2205	protein histidine kinase activity
JRI60_45835	COG3437	response regulator, receiver
JRI60_45835	COG3850	Histidine kinase
JRI60_45865	COG0515	serine threonine protein kinase
JRI60_45865	COG3266	domain, Protein
JRI60_45900	COG5002	protein histidine kinase activity
JRI60_45910	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
JRI60_45925	COG2031	fatty acid transporter
JRI60_45935	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
JRI60_45950	COG1278	Cold shock
JRI60_45980	COG1309	transcriptional regulator
JRI60_45990	COG1234	tRNA 3'-trailer cleavage
JRI60_46015	COG0596	Alpha beta hydrolase
JRI60_46050	COG1574	metal-dependent hydrolase with the TIM-barrel fold
JRI60_46125	COG1764	response to oxidative stress
JRI60_46135	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JRI60_46150	COG5002	protein histidine kinase activity
JRI60_46165	COG2205	protein histidine kinase activity
JRI60_46210	COG2205	protein histidine kinase activity
JRI60_46215	COG0667	Aldo Keto reductase
JRI60_46220	COG3012	SEC-C Motif Domain Protein
JRI60_46220	COG1405	negative regulation of cell septum assembly
JRI60_46245	COG1131	(ABC) transporter
JRI60_46250	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
JRI60_46270	COG1192	Involved in chromosome partitioning
JRI60_46280	COG1396	sequence-specific DNA binding
JRI60_46300	COG1309	transcriptional regulator
JRI60_46320	COG3265	gluconokinase activity
JRI60_46345	COG0110	maltose O-acetyltransferase activity
JRI60_46365	COG0671	phosphoesterase, PA-phosphatase related
JRI60_46375	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
JRI60_46405	COG0109	protoheme IX farnesyltransferase activity
JRI60_46405	COG1612	heme a metabolic process
JRI60_46415	COG1672	PFAM Archaeal ATPase
JRI60_46415	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
JRI60_46450	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JRI60_46450	COG0574	Belongs to the PEP-utilizing enzyme family
JRI60_46470	COG1174	glycine betaine transport
JRI60_46475	COG0517	IMP dehydrogenase activity
JRI60_46475	COG1125	glycine betaine transport
JRI60_46490	COG1525	nuclease
JRI60_46505	COG2819	hydrolase of the alpha beta superfamily
JRI60_46515	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JRI60_46525	COG0438	transferase activity, transferring glycosyl groups
JRI60_46530	COG0488	(ABC) transporter
JRI60_46540	COG1131	(ABC) transporter
JRI60_46545	COG0842	Transport permease protein
JRI60_46550	COG0515	serine threonine protein kinase
JRI60_46555	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JRI60_46565	COG2252	PERMEase
JRI60_46570	COG4191	Histidine kinase
JRI60_46570	COG0784	Response regulator, receiver
JRI60_46585	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
JRI60_46640	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JRI60_46650	COG0551	DNA topoisomerase type I activity
JRI60_46650	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JRI60_46670	COG0436	Aminotransferase
JRI60_46695	COG4251	negative regulation of phosphorylation
JRI60_46715	COG4774	siderophore transport
JRI60_46720	COG3128	pkhd-type hydroxylase
JRI60_46730	COG5002	protein histidine kinase activity
JRI60_46740	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JRI60_46745	COG0745	RESPONSE REGULATOR receiver
JRI60_46770	COG2182	Extracellular solute-binding protein
JRI60_46775	COG4191	Histidine kinase
JRI60_46780	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JRI60_46785	COG0318	PFAM AMP-dependent synthetase and ligase
JRI60_46820	COG4771	TonB-dependent receptor
JRI60_46825	COG0515	serine threonine protein kinase
JRI60_46830	COG1132	(ABC) transporter
JRI60_46835	COG1132	(ABC) transporter
JRI60_46850	COG2816	NAD+ diphosphatase activity
JRI60_46855	COG0602	queuosine metabolic process
JRI60_46875	COG1121	(ABC) transporter
JRI60_46885	COG2827	Endonuclease containing a URI domain
JRI60_46900	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JRI60_46905	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JRI60_46910	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JRI60_46915	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
JRI60_46935	COG0745	RESPONSE REGULATOR receiver
JRI60_46970	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
JRI60_46985	COG1309	transcriptional regulator
JRI60_47025	COG0765	amino acid transport
JRI60_47030	COG1126	abc transporter atp-binding protein
JRI60_47035	COG3387	PFAM Glycoside hydrolase 15-related
JRI60_47050	COG0604	alcohol dehydrogenase
JRI60_47050	COG3321	synthase
JRI60_47090	COG2843	Capsule synthesis protein
JRI60_47100	COG0386	Belongs to the glutathione peroxidase family
JRI60_47115	COG1309	transcriptional regulator
JRI60_47145	COG2815	serine threonine protein kinase
JRI60_47145	COG0515	serine threonine protein kinase
JRI60_47160	COG0625	glutathione transferase activity
JRI60_47165	COG1215	transferase activity, transferring glycosyl groups
JRI60_47170	COG5000	phosphorelay sensor kinase activity
JRI60_47205	COG0346	lactoylglutathione lyase activity
JRI60_47220	COG2267	carboxylic ester hydrolase activity
JRI60_47240	COG2204	response regulator
JRI60_47245	COG5000	phosphorelay sensor kinase activity
JRI60_47270	COG2815	serine threonine protein kinase
JRI60_47270	COG0515	serine threonine protein kinase
JRI60_47275	COG0745	RESPONSE REGULATOR receiver
JRI60_47280	COG0745	RESPONSE REGULATOR receiver
JRI60_47285	COG0166	Belongs to the GPI family
JRI60_47295	COG2124	cytochrome p450
JRI60_47315	COG0515	serine threonine protein kinase
JRI60_47320	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_47325	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JRI60_47330	COG3844	kynureninase activity
JRI60_47340	COG0662	Cupin 2, conserved barrel domain protein
JRI60_47365	COG0840	transmembrane signaling receptor activity
JRI60_47415	COG3437	response regulator, receiver
JRI60_47415	COG4999	Histidine kinase
JRI60_47415	COG3850	Histidine kinase
JRI60_47415	COG2205	protein histidine kinase activity
JRI60_47460	COG1404	Belongs to the peptidase S8 family
JRI60_47500	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
JRI60_47530	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JRI60_47545	COG1012	belongs to the aldehyde dehydrogenase family
JRI60_47565	COG2205	protein histidine kinase activity
JRI60_47565	COG0784	Response regulator, receiver
JRI60_47570	COG2815	serine threonine protein kinase
JRI60_47570	COG0515	serine threonine protein kinase
JRI60_47600	COG1408	metallophosphoesterase
JRI60_47630	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
JRI60_47635	COG0372	Belongs to the citrate synthase family
JRI60_47665	COG1337	RAMP superfamily
JRI60_47705	COG2815	serine threonine protein kinase
JRI60_47705	COG0515	serine threonine protein kinase
JRI60_47715	COG0012	GTP binding
JRI60_47720	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
JRI60_47725	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JRI60_47730	COG0356	it plays a direct role in the translocation of protons across the membrane
JRI60_47755	COG1881	PFAM PEBP family protein
JRI60_47760	COG3852	Histidine kinase
JRI60_47790	COG1595	DNA-templated transcription, initiation
JRI60_47835	COG2124	cytochrome p450
JRI60_47870	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
JRI60_47875	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
JRI60_47890	COG2205	protein histidine kinase activity
JRI60_47930	COG0640	Transcriptional regulator
JRI60_47935	COG1902	pentaerythritol trinitrate reductase activity
JRI60_47945	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JRI60_47975	COG0753	catalase activity
JRI60_48060	COG2205	protein histidine kinase activity
JRI60_48115	COG0583	DNA-binding transcription factor activity
JRI60_48135	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_48185	COG2204	response regulator
JRI60_48190	COG0596	Alpha beta hydrolase
JRI60_48195	COG1515	deoxyribonuclease V activity
JRI60_48205	COG0515	serine threonine protein kinase
JRI60_48225	COG2814	Major facilitator Superfamily
JRI60_48230	COG0631	protein serine/threonine phosphatase activity
JRI60_48240	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JRI60_48270	COG2205	protein histidine kinase activity
JRI60_48280	COG2172	sigma factor antagonist activity
JRI60_48285	COG1366	Belongs to the anti-sigma-factor antagonist family
JRI60_48290	COG1366	Belongs to the anti-sigma-factor antagonist family
JRI60_48295	COG0515	serine threonine protein kinase
JRI60_48300	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
JRI60_48345	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
JRI60_48360	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
JRI60_48365	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
JRI60_48385	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JRI60_48420	COG2204	response regulator
JRI60_48425	COG0189	ligase activity
JRI60_48460	COG0823	Involved in the tonB-independent uptake of proteins
JRI60_48485	COG2155	Conserved Protein
JRI60_48490	COG0823	Involved in the tonB-independent uptake of proteins
JRI60_48490	COG4946	Tricorn protease homolog
JRI60_48490	COG1506	peptidase
JRI60_48535	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JRI60_48540	COG2205	protein histidine kinase activity
JRI60_48565	COG1196	nuclear chromosome segregation
JRI60_48590	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JRI60_48600	COG2339	peptidase activity
JRI60_48635	COG1408	metallophosphoesterase
JRI60_48660	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JRI60_48665	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JRI60_48690	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JRI60_48700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JRI60_48700	COG4191	Histidine kinase
JRI60_48705	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JRI60_48720	COG0515	serine threonine protein kinase
JRI60_48725	COG0443	Heat shock 70 kDa protein
JRI60_48775	COG4249	Peptidase C14 caspase catalytic subunit p20
JRI60_48775	COG2319	Wd-40 repeat
JRI60_48840	COG2815	serine threonine protein kinase
JRI60_48840	COG0515	serine threonine protein kinase
JRI60_48875	COG1012	belongs to the aldehyde dehydrogenase family
JRI60_48890	COG2205	protein histidine kinase activity
JRI60_49010	COG5507	3-demethylubiquinone-9 3-methyltransferase
JRI60_49035	COG1643	Atp-dependent helicase
JRI60_49060	COG1196	nuclear chromosome segregation
JRI60_49090	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JRI60_49115	COG2133	pyrroloquinoline quinone binding
JRI60_49125	COG0583	DNA-binding transcription factor activity
JRI60_49210	COG2181	nitrate reductase activity
JRI60_49210	COG0247	lactate metabolic process
JRI60_49215	COG0823	Involved in the tonB-independent uptake of proteins
JRI60_49230	COG2205	protein histidine kinase activity
JRI60_49230	COG3850	Histidine kinase
JRI60_49230	COG4999	Histidine kinase
JRI60_49230	COG3437	response regulator, receiver
JRI60_49235	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JRI60_49260	COG0848	biopolymer transport protein
JRI60_49280	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JRI60_49300	COG0515	serine threonine protein kinase
JRI60_49320	COG0745	RESPONSE REGULATOR receiver
JRI60_49325	COG5002	protein histidine kinase activity
JRI60_49330	COG0784	Response regulator, receiver
JRI60_49335	COG4251	negative regulation of phosphorylation
JRI60_49350	COG0515	serine threonine protein kinase
JRI60_49365	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
JRI60_49385	COG4106	trans-aconitate 2-methyltransferase activity
JRI60_49400	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
JRI60_49405	COG3387	PFAM Glycoside hydrolase 15-related
JRI60_49425	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_49445	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JRI60_49500	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JRI60_49515	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JRI60_49535	COG3186	Phenylalanine-4-hydroxylase
JRI60_49540	COG2072	flavoprotein involved in K transport
JRI60_49545	COG0657	acetylesterase activity
JRI60_49600	COG0625	glutathione transferase activity
JRI60_49605	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JRI60_49605	COG2169	Transcriptional regulator
JRI60_49610	COG0667	Aldo Keto reductase
JRI60_49630	COG0640	Transcriptional regulator
JRI60_49635	COG0625	glutathione transferase activity
JRI60_49640	COG0583	DNA-binding transcription factor activity
JRI60_49695	COG2205	protein histidine kinase activity
JRI60_49710	COG2205	protein histidine kinase activity
JRI60_49750	COG4191	Histidine kinase
JRI60_49775	COG5002	protein histidine kinase activity
JRI60_49780	COG1672	PFAM Archaeal ATPase
JRI60_49780	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
JRI60_49810	COG0640	Transcriptional regulator
JRI60_49835	COG0582	viral genome integration into host DNA
JRI60_49875	COG3344	reverse transcriptase
JRI60_49905	COG4372	Transposase
JRI60_49945	COG0024	Methionine aminopeptidase
JRI60_49955	COG2207	Transcriptional regulator
JRI60_49960	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
JRI60_50000	COG2815	serine threonine protein kinase
JRI60_50000	COG0515	serine threonine protein kinase
JRI60_50100	COG2267	carboxylic ester hydrolase activity
JRI60_50115	COG2207	Transcriptional regulator
JRI60_50130	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
JRI60_50160	COG0657	acetylesterase activity
JRI60_50165	COG0515	serine threonine protein kinase
JRI60_50165	COG2815	serine threonine protein kinase
JRI60_50190	COG4257	antibiotic catabolic process
JRI60_50210	COG1595	DNA-templated transcription, initiation
JRI60_50215	COG0515	serine threonine protein kinase
JRI60_50240	COG0515	serine threonine protein kinase
JRI60_50255	COG1012	belongs to the aldehyde dehydrogenase family
JRI60_50265	COG0583	DNA-binding transcription factor activity
JRI60_50285	COG2124	cytochrome p450
JRI60_50290	COG1131	(ABC) transporter
JRI60_50295	COG0842	Transport permease protein
JRI60_50310	COG0515	serine threonine protein kinase
JRI60_50335	COG4566	intracellular signal transduction
JRI60_50340	COG4566	intracellular signal transduction
JRI60_50355	COG2267	carboxylic ester hydrolase activity
JRI60_50360	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_50390	COG0644	oxidoreductase
JRI60_50430	COG1960	acyl-CoA dehydrogenase activity
JRI60_50500	COG0318	PFAM AMP-dependent synthetase and ligase
JRI60_50505	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JRI60_50515	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_50530	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
JRI60_50540	COG2226	methyltransferase
JRI60_50555	COG2267	carboxylic ester hydrolase activity
JRI60_50560	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JRI60_50565	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JRI60_50570	COG5002	protein histidine kinase activity
JRI60_50570	COG2205	protein histidine kinase activity
JRI60_50570	COG0784	Response regulator, receiver
JRI60_50575	COG5002	protein histidine kinase activity
JRI60_50635	COG1764	response to oxidative stress
JRI60_50640	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JRI60_50645	COG1846	Transcriptional regulator
JRI60_50705	COG0583	DNA-binding transcription factor activity
JRI60_50755	COG0435	Glutathione S-transferase
JRI60_50760	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
JRI60_50760	COG1672	PFAM Archaeal ATPase
JRI60_50765	COG0446	pyridine nucleotide-disulphide oxidoreductase
JRI60_50770	COG2204	response regulator
JRI60_50780	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JRI60_50785	COG0730	response to heat
JRI60_50805	COG3268	Saccharopine dehydrogenase
JRI60_50835	COG3311	Transcriptional regulator
JRI60_50840	COG5002	protein histidine kinase activity
JRI60_50845	COG2205	protein histidine kinase activity
JRI60_50850	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
JRI60_50860	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
JRI60_50870	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JRI60_50875	COG3228	Belongs to the MtfA family
JRI60_50890	COG0288	reversible hydration of carbon dioxide
JRI60_50945	COG2267	carboxylic ester hydrolase activity
JRI60_50960	COG4221	oxidoreductase activity
JRI60_50970	COG0596	Alpha beta hydrolase
JRI60_51000	COG5000	phosphorelay sensor kinase activity
JRI60_51020	COG0673	inositol 2-dehydrogenase activity
JRI60_51045	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
JRI60_51055	COG5464	transposase or invertase
JRI60_51095	COG3409	Peptidoglycan-binding domain 1 protein
JRI60_51095	COG5632	N-Acetylmuramoyl-L-alanine amidase
JRI60_51095	COG1388	LysM domain
JRI60_51140	COG2124	cytochrome p450
JRI60_51150	COG1672	PFAM Archaeal ATPase
JRI60_51150	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
JRI60_51165	COG3540	Alkaline phosphatase
JRI60_51195	COG0038	chloride channel
JRI60_51205	COG0346	lactoylglutathione lyase activity
JRI60_51230	COG0346	lactoylglutathione lyase activity
JRI60_51260	COG2815	serine threonine protein kinase
JRI60_51260	COG0515	serine threonine protein kinase
JRI60_51270	COG3047	cAMP biosynthetic process
JRI60_51270	COG2885	chlorophyll binding
JRI60_51310	COG0281	malic enzyme
JRI60_51315	COG2205	protein histidine kinase activity
JRI60_51360	COG4191	Histidine kinase
JRI60_51360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JRI60_51395	COG0318	PFAM AMP-dependent synthetase and ligase
JRI60_51455	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JRI60_51520	COG0745	RESPONSE REGULATOR receiver
JRI60_51565	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JRI60_51585	COG0154	amidase activity
JRI60_51600	COG0589	response to stress
JRI60_51610	COG3550	peptidyl-serine autophosphorylation
JRI60_51620	COG2755	lipolytic protein G-D-S-L family
JRI60_51620	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
JRI60_51640	COG0778	Nitroreductase
JRI60_51645	COG0492	ferredoxin-NADP+ reductase activity
JRI60_51665	COG0515	serine threonine protein kinase
JRI60_51685	COG2321	neutral zinc metallopeptidase
JRI60_51695	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JRI60_51700	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
JRI60_51705	COG0544	peptidyl-prolyl cis-trans isomerase activity
JRI60_51720	COG0596	Alpha beta hydrolase
JRI60_51725	COG1028	Short-chain dehydrogenase reductase Sdr
JRI60_51730	COG1942	4-Oxalocrotonate Tautomerase
JRI60_51750	COG0352	thiamine-phosphate diphosphorylase activity
JRI60_51755	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
JRI60_51820	COG4946	Tricorn protease homolog
JRI60_51820	COG1506	peptidase
JRI60_51820	COG0823	Involved in the tonB-independent uptake of proteins
JRI60_51840	COG0515	serine threonine protein kinase
JRI60_51840	COG2815	serine threonine protein kinase
JRI60_51845	COG4191	Histidine kinase
JRI60_51905	COG0515	serine threonine protein kinase
JRI60_51905	COG2815	serine threonine protein kinase
JRI60_51930	COG1690	Belongs to the RtcB family
JRI60_51955	COG2234	aminopeptidase activity
JRI60_51995	COG1434	Gram-negative-bacterium-type cell wall biogenesis
JRI60_52025	COG0515	serine threonine protein kinase
JRI60_52025	COG2815	serine threonine protein kinase
JRI60_52060	COG3387	PFAM Glycoside hydrolase 15-related
JRI60_52080	COG0477	Major facilitator Superfamily
JRI60_52085	COG0784	Response regulator, receiver
JRI60_52110	COG0515	serine threonine protein kinase
JRI60_52155	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JRI60_52165	COG0667	Aldo Keto reductase
JRI60_52200	COG0515	serine threonine protein kinase
JRI60_52240	COG0515	serine threonine protein kinase
JRI60_52285	COG0189	ligase activity
JRI60_52290	COG1136	(ABC) transporter
JRI60_52320	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
JRI60_52340	COG3214	Protein conserved in bacteria
JRI60_52355	COG0515	serine threonine protein kinase
JRI60_52355	COG2815	serine threonine protein kinase
JRI60_52480	COG2815	serine threonine protein kinase
JRI60_52480	COG0515	serine threonine protein kinase
JRI60_52485	COG2814	Major facilitator Superfamily
JRI60_52515	COG1752	Esterase of the alpha-beta hydrolase superfamily
JRI60_52545	COG3409	Peptidoglycan-binding domain 1 protein
JRI60_52570	COG2226	methyltransferase
JRI60_52575	COG2205	protein histidine kinase activity
JRI60_52615	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JRI60_52620	COG0230	Belongs to the bacterial ribosomal protein bL34 family
JRI60_52625	COG0594	ribonuclease P activity
JRI60_52630	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
JRI60_52635	COG0706	membrane insertase activity
JRI60_52650	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
JRI60_52670	COG0702	epimerase
JRI60_52715	COG0616	signal peptide processing
JRI60_52720	COG2267	carboxylic ester hydrolase activity
JRI60_52735	COG0612	Peptidase, M16
JRI60_52740	COG2226	methyltransferase
JRI60_52745	COG1104	cysteine desulfurase activity
JRI60_52760	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
JRI60_52765	COG0537	adenosine 5'-monophosphoramidase activity
JRI60_52790	COG0515	serine threonine protein kinase