locus-tag	class	description
AAQM_0001	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
AAQM_0002	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
AAQM_0003	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AAQM_0004	ENOG4105CAY	ferredoxin--nadp reductase
AAQM_0005	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
AAQM_0008	ENOG4105W39	Membrane
AAQM_0010	ENOG4105EI2	Pseudouridine synthase
AAQM_0011	ENOG4107QTF	adenylosuccinate lyase
AAQM_0012	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
AAQM_0013	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
AAQM_0016	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
AAQM_0020	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
AAQM_0022	ENOG4105BZ8	glutamate synthase
AAQM_0024	ENOG4105CE9	30S ribosomal protein S2
AAQM_0027	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
AAQM_0028	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
AAQM_0029	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
AAQM_0032	ENOG4105BZU	Histidine kinase
AAQM_0033	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
AAQM_0034	ENOG4107QR9	Iron-sulfur cluster binding protein
AAQM_0035	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
AAQM_0037	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
AAQM_0038	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
AAQM_0039	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
AAQM_0040	ENOG4105C1J	atp-dependent rna helicase
AAQM_0041	ENOG4105CJ3	phosphate transporter
AAQM_0043	ENOG4105CAQ	asparagine synthetase
AAQM_0045	ENOG4105E7Q	Cob(II)yrinic acid a,c-diamide reductase
AAQM_0049	ENOG4108IAB	Phoh family
AAQM_0050	ENOG4108YXA	Membrane
AAQM_0051	ENOG4105D1H	recombination factor protein RarA
AAQM_0052	ENOG4105FE9	pseudouridine synthase
AAQM_0053	ENOG4105C2X	Arabinose 5-phosphate isomerase
AAQM_0055	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
AAQM_0056	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
AAQM_0059	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
AAQM_0060	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
AAQM_0061	ENOG4105VFU	Rna-binding protein
AAQM_0067	ENOG4108IJF	Heavy metal efflux pump, CzcA
AAQM_0068	ENOG4108YYC	ycei family
AAQM_0071	ENOG4105D6E	homoserine dehydrogenase
AAQM_0072	ENOG4105CHM	Aminotransferase
AAQM_0076	ENOG41082DI	50s ribosomal protein l31
AAQM_0077	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
AAQM_0083	ENOG4105EYG	tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site (By similarity)
AAQM_0093	ENOG4107QHF	type ii secretion system protein e
AAQM_0099	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
AAQM_0101	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
AAQM_0102	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
AAQM_0103	ENOG41084QV	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
AAQM_0104	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
AAQM_0105	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
AAQM_0106	ENOG4105C2I	pirin domain protein
AAQM_0107	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
AAQM_0109	ENOG4105FS7	Transcriptional regulator
AAQM_0110	ENOG4107UUH	Aminotransferase
AAQM_0111	ENOG4105CYE	ATP phosphoribosyltransferase regulatory subunit
AAQM_0112	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
AAQM_0114	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
AAQM_0118	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
AAQM_0121	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
AAQM_0122	ENOG4105D1F	ATP-binding protein
AAQM_0124	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
AAQM_0127	ENOG4105CM2	brancheD-chain amino acid aminotransferase
AAQM_0129	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
AAQM_0131	ENOG4105C3R	Methionine synthase
AAQM_0132	ENOG4105D3R	alkyl hydroperoxide reductase
AAQM_0135	ENOG4108I6A	alcohol dehydrogenase
AAQM_0136	ENOG4105BZU	Histidine kinase
AAQM_0138	ENOG4105DZ1	carboxypeptidase
AAQM_0141	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
AAQM_0145	ENOG4105F3T	(LipO)protein
AAQM_0146	ENOG4105CY3	ABC transporter, permease
AAQM_0147	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
AAQM_0150	ENOG4108KK1	membrane protein AbrB duplication
AAQM_0151	ENOG4105KVH	Transcriptional regulator
AAQM_0152	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
AAQM_0153	ENOG4105DDK	oxidoreductase, beta subunit
AAQM_0154	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
AAQM_0156	ENOG4105EJ5	oxidoreductase gamma subunit
AAQM_0157	ENOG4107XGZ	Hydrolase
AAQM_0159	ENOG4108UJD	30S ribosomal protein S9
AAQM_0160	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
AAQM_0162	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AAQM_0164	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
AAQM_0165	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
AAQM_0166	ENOG4105E2Z	phosphate ABC transporter (Permease
AAQM_0167	ENOG4105C8U	phosphate abc transporter
AAQM_0168	ENOG4105PWN	phosphate abc transporter
AAQM_0170	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
AAQM_0171	ENOG4108317	Binds directly to 16S ribosomal RNA (By similarity)
AAQM_0172	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
AAQM_0173	ENOG410813J	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
AAQM_0174	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
AAQM_0175	ENOG41080AZ	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
AAQM_0176	ENOG4107SA8	fad-dependent pyridine nucleotide-disulfide oxidoreductase
AAQM_0179	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
AAQM_0180	ENOG41084M8	50s ribosomal protein L35
AAQM_0181	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
AAQM_0189	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
AAQM_0193	ENOG4105C0W	non-ribosomal peptide synthetase
AAQM_0194	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
AAQM_0196	ENOG4105CJ1	ABC, transporter
AAQM_0201	ENOG4105CHR	reductase
AAQM_0202	ENOG4105C84	Histidine ammonia-lyase
AAQM_0207	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
AAQM_0208	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
AAQM_0213	ENOG4105KNE	Phosphatidate cytidylyltransferase
AAQM_0214	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
AAQM_0218	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
AAQM_0220	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
AAQM_0221	ENOG4105VF7	tolerance protein
AAQM_0222	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
AAQM_0230	ENOG4105D9Q	decarboxylase (Beta subunit)
AAQM_0231	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
AAQM_0235	ENOG4105C8Q	Methyl-accepting chemotaxis
AAQM_0239	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AAQM_0241	ENOG4108JJA	ABC, transporter
AAQM_0242	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
AAQM_0244	ENOG4105BZU	Histidine kinase
AAQM_0245	ENOG4105CV1	Transketolase (EC 2.2.1.1)
AAQM_0249	ENOG41067MG	lrgb family
AAQM_0251	ENOG4105KK4	UPF0060 membrane protein
AAQM_0255	ENOG4105CHH	sulfate transporter
AAQM_0258	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
AAQM_0260	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
AAQM_0264	ENOG4108YZA	Nitrogen regulatory protein pii
AAQM_0266	ENOG4108YZA	Nitrogen regulatory protein pii
AAQM_0267	ENOG4105EKE	dihydroorotase
AAQM_0268	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
AAQM_0269	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
AAQM_0271	ENOG4105VS8	Flagellar biosynthetic protein fliq
AAQM_0276	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
AAQM_0277	ENOG4105E1Q	flagellar hook-associated protein
AAQM_0278	ENOG4107W9T	flagellar hook-associated
AAQM_0282	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
AAQM_0283	ENOG4107R03	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
AAQM_0285	ENOG410829W	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
AAQM_0286	ENOG4105GSH	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
AAQM_0288	ENOG4105EAC	phosphoserine phosphatase
AAQM_0289	ENOG4107V25	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
AAQM_0290	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
AAQM_0291	ENOG4105DRB	nucleoside-specific channel-forming protein
AAQM_0292	ENOG4105KUZ	arsenate reductase
AAQM_0293	ENOG410855J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
AAQM_0294	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
AAQM_0296	ENOG4105CHM	Aminotransferase
AAQM_0298	ENOG4105DFU	Cell wall formation (By similarity)
AAQM_0300	ENOG4105PXI	polysaccharide deacetylase
AAQM_0301	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
AAQM_0302	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
AAQM_0303	ENOG410821Z	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum (By similarity)
AAQM_0305	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
AAQM_0306	ENOG4108UUM	single-stranded DNA-binding protein
AAQM_0307	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
AAQM_0309	ENOG4105C8N	cysteinyl-tRNA synthetase
AAQM_0310	ENOG4105CHV	Transcription elongation factor NusA
AAQM_0312	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
AAQM_0313	ENOG4105KB8	(LipO)protein
AAQM_0315	ENOG4105DVY	radical SAM domain protein
AAQM_0318	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
AAQM_0319	ENOG41082UM	UPF0102 protein
AAQM_0322	ENOG4105F37	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
AAQM_0323	ENOG4105CA9	Pyruvate kinase
AAQM_0325	ENOG4105C8Y	Acetylornithine aminotransferase
AAQM_0327	ENOG4105CXT	aspartate transcarbamylase
AAQM_0332	ENOG4108UMN	azlc family
AAQM_0333	ENOG4105KMT	branched-chain amino acid
AAQM_0334	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
AAQM_0335	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
AAQM_0336	ENOG4105YQ2	50s ribosomal protein l32
AAQM_0338	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
AAQM_0340	ENOG4105D3R	alkyl hydroperoxide reductase
AAQM_0341	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
AAQM_0342	ENOG4105D82	Glutamate dehydrogenase
AAQM_0343	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
AAQM_0344	ENOG4107QMP	dna polymerase iii subunits gamma and tau
AAQM_0346	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
AAQM_0349	ENOG4105C7F	AcnD-accessory protein PrpF
AAQM_0350	ENOG4108I0Z	Aconitate hydratase
AAQM_0351	ENOG4105BZN	citrate synthase
AAQM_0352	ENOG4105CR4	methylisocitrate lyase
AAQM_0354	ENOG4105C5I	Dehydrogenase
AAQM_0359	ENOG4105C9U	ATP-dependent DNA helicase RecQ
AAQM_0360	ENOG4108BSC	Methyltransferase
AAQM_0363	ENOG4108VKG	metal-dependent hydrolase
AAQM_0368	ENOG4105E33	succinate dehydrogenase
AAQM_0369	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
AAQM_0370	ENOG4108S24	Fumarate reduCtase
AAQM_0371	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AAQM_0372	ENOG4105C8S	subunit m
AAQM_0373	ENOG4105D65	subunit l
AAQM_0374	ENOG41080EA	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AAQM_0375	ENOG4107YX3	NADH dehydrogenase subunit j
AAQM_0377	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
AAQM_0378	ENOG4108IEH	NADH dehydrogenase subunit g
AAQM_0379	ENOG4105BZN	citrate synthase
AAQM_0382	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AAQM_0383	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AAQM_0384	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AAQM_0385	ENOG4105C87	Aminotransferase class I and II
AAQM_0386	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
AAQM_0387	ENOG4107XM3	UPF0442 protein
AAQM_0388	ENOG4105DWK	Membrane
AAQM_0390	ENOG4108VHG	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
AAQM_0391	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
AAQM_0393	ENOG4105C8Q	Methyl-accepting chemotaxis
AAQM_0398	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
AAQM_0401	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
AAQM_0405	ENOG4108ZMS	Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity)
AAQM_0406	ENOG4105GXZ	Ferredoxin-type protein NapH
AAQM_0407	ENOG4108BGM	Quinol dehydrogenase periplasmic component
AAQM_0408	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
AAQM_0409	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
AAQM_0410	ENOG4108RA0	tripartite ATP-independent periplasmic transporter, DctQ component
AAQM_0411	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
AAQM_0413	ENOG410812K	response regulator receiver protein
AAQM_0414	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
AAQM_0415	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
AAQM_0418	ENOG4108I0Q	anthranilate phosphoribosyltransferase
AAQM_0419	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
AAQM_0422	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
AAQM_0423	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
AAQM_0424	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
AAQM_0425	ENOG410847I	Transcriptional regulator, BadM Rrf2 family
AAQM_0426	ENOG4108KA0	Inherit from COG: Phosphoesterase, DHHA1
AAQM_0429	ENOG4105ETX	regulatoR
AAQM_0431	ENOG4105D2N	Aldolase
AAQM_0432	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
AAQM_0434	ENOG4105D38	putrescine abc transporter
AAQM_0435	ENOG4107RUE	extracellular solute-binding protein family 1
AAQM_0440	ENOG4105VEQ	Cold shock protein
AAQM_0441	ENOG4105SG9	biopolymer transport protein, ExbD
AAQM_0444	ENOG4105BZU	Histidine kinase
AAQM_0445	ENOG4105BZU	Histidine kinase
AAQM_0447	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
AAQM_0449	ENOG4105EAH	synthase
AAQM_0450	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
AAQM_0451	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
AAQM_0453	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
AAQM_0456	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
AAQM_0457	ENOG4105VIE	preprotein translocase, subunit YajC
AAQM_0458	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
AAQM_0459	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
AAQM_0461	ENOG4105C8T	Leucyl-tRNA synthetase
AAQM_0463	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
AAQM_0465	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
AAQM_0471	ENOG4108JA2	transcriptioN-repair coupling factor
AAQM_0477	ENOG4105CBX	hi0933 family
AAQM_0478	ENOG4105C8Q	Methyl-accepting chemotaxis
AAQM_0480	ENOG410903D	sensor protein
AAQM_0481	ENOG4108HWS	Histidine kinase
AAQM_0482	ENOG4105D48	metallophosphoesterase
AAQM_0485	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
AAQM_0486	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
AAQM_0487	ENOG4108V3W	Chemotaxis protein, CheW
AAQM_0489	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
AAQM_0491	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
AAQM_0492	ENOG41084FT	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
AAQM_0494	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
AAQM_0495	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
AAQM_0496	ENOG4108ESY	Metal dependent phosphohydrolase
AAQM_0499	ENOG4107RN3	metallophosphoesterase
AAQM_0504	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AAQM_0505	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AAQM_0506	ENOG4105ECY	inositol monophosphatase
AAQM_0507	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
AAQM_0510	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
AAQM_0511	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
AAQM_0512	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
AAQM_0513	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
AAQM_0515	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
AAQM_0516	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
AAQM_0517	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
AAQM_0518	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
AAQM_0521	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
AAQM_0522	ENOG4105BZU	Histidine kinase
AAQM_0523	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
AAQM_0524	ENOG4105ECP	epimerase
AAQM_0525	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
AAQM_0528	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
AAQM_0529	ENOG4105CDV	Ompa motb domain protein
AAQM_0530	ENOG4105CDV	Ompa motb domain protein
AAQM_0531	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
AAQM_0533	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
AAQM_0534	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
AAQM_0535	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AAQM_0536	ENOG4105DC7	peptidase M24
AAQM_0537	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
AAQM_0538	ENOG4107SYB	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
AAQM_0541	ENOG4108IJ2	phosphate acetyltransferase
AAQM_0542	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
AAQM_0544	ENOG41083X2	DNA polymerase III, epsilon subunit
AAQM_0548	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
AAQM_0550	ENOG4107QN1	sodium solute
AAQM_0552	ENOG4108STX	response regulator
AAQM_0553	ENOG4105BZU	Histidine kinase
AAQM_0562	ENOG4105CEV	competence damage-inducible protein
AAQM_0563	ENOG4107RSR	Malate quinone oxidoreductase
AAQM_0564	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
AAQM_0568	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
AAQM_0573	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
AAQM_0574	ENOG4105CE9	30S ribosomal protein S2
AAQM_0575	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
AAQM_0578	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
AAQM_0579	ENOG4105BZU	Histidine kinase
AAQM_0580	ENOG4105C59	p-type ATPase
AAQM_0583	ENOG4107H6U	ABC transporter
AAQM_0584	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
AAQM_0585	ENOG4105NBF	ammecr1 domain protein
AAQM_0586	ENOG41074MP	UPF0103 Mediator of ErbB2-driven cell motility-containing protein
AAQM_0587	ENOG4107S90	membrAne
AAQM_0588	ENOG4105FDK	ABC transporter
AAQM_0595	ENOG4105QNR	S1 RNA binding domain protein
AAQM_0596	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
AAQM_0599	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
AAQM_0600	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
AAQM_0601	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
AAQM_0604	ENOG4105VTR	Integrase
AAQM_0610	ENOG4105ENA	helicase
AAQM_0612	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
AAQM_0617	ENOG41088H4	Diheme cytochrome SoxA (Sulfur oxidation)
AAQM_0627	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
AAQM_0629	ENOG4108UYN	gCN5-related N-acetyltransferase
AAQM_0632	ENOG4108YZY	peptidylprolyl cis-trans isomerase
AAQM_0634	ENOG4105BZS	acriflavin resistance protein
AAQM_0636	ENOG4108Z6K	Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant (By similarity)
AAQM_0637	ENOG4108JPW	Aminotransferase
AAQM_0640	ENOG4105DR5	peptidase
AAQM_0642	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
AAQM_0643	ENOG4105DC1	bifunctional purine biosynthesis protein purh
AAQM_0648	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
AAQM_0649	ENOG4105E0X	reductase
AAQM_0650	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
AAQM_0653	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
AAQM_0656	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AAQM_0657	ENOG4105VG0	50S ribosomal protein l34
AAQM_0658	ENOG41067YR	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
AAQM_0659	ENOG4108512	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
AAQM_0660	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
AAQM_0662	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
AAQM_0665	ENOG4105D0M	Protease HtpX homolog
AAQM_0666	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
AAQM_0667	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
AAQM_0669	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
AAQM_0671	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
AAQM_0672	ENOG4105K46	50S ribosomal protein l27
AAQM_0673	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AAQM_0674	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
AAQM_0675	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
AAQM_0677	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
AAQM_0678	ENOG4107QJE	Chromosome Partitioning Protein
AAQM_0679	ENOG4105FA0	parb-like partition protein
AAQM_0681	ENOG4105YF2	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
AAQM_0682	ENOG4105PQH	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
AAQM_0683	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
AAQM_0684	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
AAQM_0685	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
AAQM_0686	ENOG41082MC	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
AAQM_0687	ENOG4105E02	MotA TolQ exbB proton channel
AAQM_0688	ENOG4105M8F	Biopolymer transport protein exbD tolR
AAQM_0690	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
AAQM_0691	ENOG4108UQY	Iron-storage protein
AAQM_0694	ENOG4108YZY	peptidylprolyl cis-trans isomerase
AAQM_0695	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
AAQM_0696	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
AAQM_0698	ENOG4105CQZ	Histidine kinase
AAQM_0699	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AAQM_0700	ENOG4108IJ0	Aspartate ammonia-lyase
AAQM_0702	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
AAQM_0703	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
AAQM_0704	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
AAQM_0706	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
AAQM_0707	ENOG4105CYW	agmatinase
AAQM_0710	ENOG4105CNM	Receptor
AAQM_0711	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
AAQM_0714	ENOG4105F1N	DNA alkylation repair
AAQM_0715	ENOG4108Z66	YbaK ebsC protein
AAQM_0716	ENOG4105C7I	Dehydrogenase
AAQM_0719	ENOG4105BZU	Histidine kinase
AAQM_0722	ENOG4105F1S	paraquat-inducible protein a
AAQM_0723	ENOG4105DY2	Paraquat-inducible protein b
AAQM_0725	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
AAQM_0726	ENOG4105BZU	Histidine kinase
AAQM_0728	ENOG4105RAK	Histidine kinase
AAQM_0731	ENOG4105H4F	exported protein
AAQM_0732	ENOG4105DHQ	Histidine kinase
AAQM_0733	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
AAQM_0735	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
AAQM_0736	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
AAQM_0737	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
AAQM_0743	ENOG4105E7W	lamb ycsf family protein
AAQM_0747	ENOG4105BZU	Histidine kinase
AAQM_0750	ENOG4105C1J	atp-dependent rna helicase
AAQM_0751	ENOG4105BZU	Histidine kinase
AAQM_0752	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
AAQM_0754	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
AAQM_0756	ENOG4108N6H	6-pyruvoyl tetrahydrobiopterin synthase
AAQM_0757	ENOG4105EKE	dihydroorotase
AAQM_0758	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
AAQM_0766	ENOG4105CE1	Ferrous iron transport protein b
AAQM_0767	ENOG4105XFK	Ferrous iron transport protein A
AAQM_0770	ENOG4107F3C	Hemin uptake protein
AAQM_0771	ENOG4105D05	Receptor
AAQM_0773	ENOG41074H6	response regulator
AAQM_0774	ENOG4105DFG	type I secretion outer membrane protein
AAQM_0775	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
AAQM_0777	ENOG4106R49	Methyltransferase
AAQM_0778	ENOG4105D05	Receptor
AAQM_0782	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
AAQM_0783	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
AAQM_0785	ENOG4105C8Q	Methyl-accepting chemotaxis
AAQM_0786	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
AAQM_0787	ENOG4105CPF	Cell wall formation (By similarity)
AAQM_0788	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
AAQM_0789	ENOG4105DFU	Cell wall formation (By similarity)
AAQM_0792	ENOG4107QMZ	Dehydrogenase
AAQM_0793	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
AAQM_0794	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
AAQM_0795	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
AAQM_0796	ENOG4105KZZ	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
AAQM_0797	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AAQM_0798	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
AAQM_0799	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
AAQM_0800	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
AAQM_0801	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
AAQM_0802	ENOG41084HJ	50s ribosomal protein l29
AAQM_0803	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
AAQM_0804	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
AAQM_0805	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
AAQM_0806	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AAQM_0807	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
AAQM_0808	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
AAQM_0809	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
AAQM_0810	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
AAQM_0811	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
AAQM_0812	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
AAQM_0813	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
AAQM_0814	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
AAQM_0815	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
AAQM_0817	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
AAQM_0819	ENOG4105C9M	aspartyl-trna synthetase
AAQM_0822	ENOG4105CCT	upf0313 protein
AAQM_0823	ENOG4105N14	lysine exporter protein LysE YggA
AAQM_0824	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
AAQM_0825	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
AAQM_0827	ENOG4107SDU	Methyl-accepting chemotaxis
AAQM_0829	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
AAQM_0830	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
AAQM_0831	ENOG4105BZU	Histidine kinase
AAQM_0832	ENOG4108KN0	Choline kinase
AAQM_0833	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
AAQM_0834	ENOG4108V06	Glutathione peroxidase
AAQM_0835	ENOG4107SDU	Methyl-accepting chemotaxis
AAQM_0836	ENOG4105C8Q	Methyl-accepting chemotaxis
AAQM_0837	ENOG4105C8Q	Methyl-accepting chemotaxis
AAQM_0841	ENOG41062JF	Transcriptional regulator
AAQM_0843	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
AAQM_0847	ENOG4105BZU	Histidine kinase
AAQM_0848	ENOG4105CGK	Exodeoxyribonuclease III
AAQM_0854	ENOG4107QP8	phosphohexose isomerase
AAQM_0855	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
AAQM_0856	ENOG4107QKV	phosphomannomutase
AAQM_0863	ENOG4105NBK	UPF0345 protein
AAQM_0867	ENOG4105C3G	gtp-binding protein
AAQM_0868	ENOG4105C7N	Xanthine uracil vitamin C permease
AAQM_0869	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
AAQM_0872	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
AAQM_0873	ENOG4105C2W	permease
AAQM_0874	ENOG4108VPT	UPF0234 protein
AAQM_0878	ENOG4107VIJ	nudix hydrolase
AAQM_0880	ENOG4105HDD	phospholipase
AAQM_0881	ENOG4105DJV	ribulose-phosphate 3-epimerase
AAQM_0882	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
AAQM_0883	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
AAQM_0884	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
AAQM_0886	ENOG4105DQU	oxidoreductase, subunit beta
AAQM_0887	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
AAQM_0889	ENOG41060K3	Methyltransferase
AAQM_0890	ENOG4105QTX	Pfam:UPF0153
AAQM_0892	ENOG4105DK0	Indole-3-glycerol phosphate synthase
AAQM_0894	ENOG4105VSH	4-oxalocrotonate tautomerase
AAQM_0895	ENOG4105DFA	alanine racemase domain protein
AAQM_0896	ENOG4105DZP	Membrane-associated zinc metalloprotease
AAQM_0897	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
AAQM_0898	ENOG4105CAN	Short-chain dehydrogenase reductase Sdr
AAQM_0899	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
AAQM_0902	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
AAQM_0903	ENOG4105BZ1	(ABC) transporter
AAQM_0904	ENOG4105CJR	Integral membrane protein (MviN
AAQM_0906	ENOG4108RAC	Rubrerythrin
AAQM_0908	ENOG4105FEU	K -dependent Na -Ca exchanger
AAQM_0909	ENOG41080V7	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
AAQM_0911	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
AAQM_0918	ENOG4105CA0	peroxidase
AAQM_0919	ENOG4105BZU	Histidine kinase
AAQM_0921	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
AAQM_0922	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AAQM_0924	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
AAQM_0925	ENOG4106H78	methyltransferase
AAQM_0926	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AAQM_0928	ENOG4105E1F	short-chain dehydrogenase reductase
AAQM_0931	ENOG4105NQN	cytochrome C
AAQM_0936	ENOG4108PQF	modD protein
AAQM_0938	ENOG4105KTH	gatB Yqey
AAQM_0939	ENOG4105C5H	ABC transporter
AAQM_0940	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
AAQM_0941	ENOG4105C8Q	Methyl-accepting chemotaxis
AAQM_0945	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
AAQM_0946	ENOG4105CDV	Ompa motb domain protein
AAQM_0947	ENOG4108JJA	ABC, transporter
AAQM_0948	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
AAQM_0949	ENOG41061ZR	Transcriptional regulator
AAQM_0954	ENOG4105DHT	Metal Dependent Phosphohydrolase
AAQM_0955	ENOG41076HS	cation diffusion facilitator family transporter
AAQM_0956	ENOG4105CHM	Aminotransferase
AAQM_0959	ENOG4108IYU	L-aspartate oxidase
AAQM_0960	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
AAQM_0963	ENOG4106A2Z	transcriptional regulator antitoxin, MazE
AAQM_0965	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
AAQM_0966	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
AAQM_0967	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AAQM_0975	ENOG4105HF0	Membrane
AAQM_0976	ENOG4107TVJ	,Oxidoreductase FAD NAD(P)-binding
AAQM_0981	ENOG4105DIV	Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD( ) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds (By similarity)
AAQM_0982	ENOG4105DF3	Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds (By similarity)
AAQM_0985	ENOG4105DEN	Luciferase family
AAQM_0986	ENOG4108JNI	Alpha beta hydrolase
AAQM_0987	ENOG41063V1	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
AAQM_0990	ENOG4105CQC	Prephenate dehydratase
AAQM_0991	ENOG4105C08	Histidine kinase
AAQM_0993	ENOG4105BZU	Histidine kinase
AAQM_0998	ENOG4105C9Q	fumarate hydratase class II
AAQM_1005	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
AAQM_1007	ENOG4105CQ7	ATP-dependent helicase
AAQM_1010	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
AAQM_1014	ENOG4107YYT	May reduce aminoacrylate peracid to aminoacrylate. Required to remove a toxic intermediate produce by the pyrimidine nitrogen degradation (By similarity)
AAQM_1019	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
AAQM_1020	ENOG4105PW4	Sugar fermentation stimulation protein homolog
AAQM_1023	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
AAQM_1024	ENOG4105EI2	Pseudouridine synthase
AAQM_1025	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
AAQM_1031	ENOG4105E1F	short-chain dehydrogenase reductase
AAQM_1032	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
AAQM_1041	ENOG4105D9P	serine threonine protein kinase
AAQM_1044	ENOG4105C37	(CBS) domain
AAQM_1045	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
AAQM_1046	ENOG4105DSF	transport protein
AAQM_1049	ENOG4108JU6	CBS domain protein
AAQM_1052	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
AAQM_1054	ENOG4108RZE	Tetr family transcriptional regulator
AAQM_1057	ENOG4105C1J	atp-dependent rna helicase
AAQM_1059	ENOG4105D7W	serine acetyltransferase
AAQM_1060	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
AAQM_1061	ENOG4105CUT	histidyl-tRNA synthetase
AAQM_1062	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
AAQM_1063	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
AAQM_1064	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
AAQM_1066	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
AAQM_1067	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
AAQM_1068	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
AAQM_1070	ENOG4105F8V	Hydrolase, tatD family
AAQM_1072	ENOG4105K6T	rare lipoprotein A
AAQM_1073	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
AAQM_1074	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
AAQM_1077	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
AAQM_1079	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
AAQM_1080	ENOG41090Y0	FMN-binding protein
AAQM_1082	ENOG4105BZS	acriflavin resistance protein
AAQM_1084	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
AAQM_1086	ENOG4105CN7	Flagellar biosynthetic protein FliP
AAQM_1087	ENOG4107RVG	penicillin-binding protein
AAQM_1097	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
AAQM_1098	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
AAQM_1101	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
AAQM_1103	ENOG4105DWV	Homoserine O-trans-acetylase
AAQM_1105	ENOG4105C98	muts2 protein
AAQM_1109	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
AAQM_1111	ENOG4105DKW	ABC transporter
AAQM_1114	ENOG4105CQC	Prephenate dehydratase
AAQM_1122	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
AAQM_1129	ENOG4108V1U	phospholipid-binding protein
AAQM_1131	ENOG4105C8Q	Methyl-accepting chemotaxis
AAQM_1134	ENOG4105CBS	Chea signal transduction histidine kinase
AAQM_1135	ENOG4105WH1	Two component transcriptional regulator luxr family
AAQM_1137	ENOG4108QDE	fad dependent oxidoreductase
AAQM_1140	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
AAQM_1142	ENOG4105QNF	Outer membrane lipoprotein
AAQM_1145	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
AAQM_1148	ENOG4105BZU	Histidine kinase
AAQM_1150	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
AAQM_1153	ENOG4105QNF	Outer membrane lipoprotein
AAQM_1155	ENOG4107FW0	short-chain dehydrogenase reductase
AAQM_1157	ENOG4105C5H	ABC transporter
AAQM_1158	ENOG4108S4H	thioesterase Superfamily protein
AAQM_1159	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
AAQM_1160	ENOG4105C8Q	Methyl-accepting chemotaxis
AAQM_1161	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
AAQM_1162	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
AAQM_1165	ENOG4105KVH	Transcriptional regulator
AAQM_1166	ENOG4105NF4	modulator of drug activity
AAQM_1168	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AAQM_1169	ENOG4108RCM	Nitroreductase
AAQM_1172	ENOG4105BZU	Histidine kinase
AAQM_1174	ENOG410841J	DNA-binding protein Hu
AAQM_1176	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
AAQM_1182	ENOG4105CEY	Amp-dependent synthetase and ligase
AAQM_1184	ENOG4105DJI	Methylaspartate mutase, E subunit
AAQM_1187	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
AAQM_1188	ENOG4105E9K	Isocitrate dehydrogenase
AAQM_1191	ENOG4105D60	lipoprotein releasing system transmembrane protein
AAQM_1192	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
AAQM_1193	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
AAQM_1196	ENOG4105EMA	Periplasmic binding protein LacI transcriptional regulator
AAQM_1197	ENOG4105BZU	Histidine kinase
AAQM_1198	ENOG4106032	Glutathionylspermidine synthase
AAQM_1199	ENOG4108UHV	Lipoprotein
AAQM_1200	ENOG41085FC	arsR family transcriptional regulator
AAQM_1203	ENOG4105FGV	Chromate
AAQM_1206	ENOG4105C8Q	Methyl-accepting chemotaxis
AAQM_1208	ENOG4107YD3	Thioesterase
AAQM_1210	ENOG4105C2Y	STE24 endopeptidase EC 3.4.24.84
AAQM_1211	ENOG4105CGY	Dna recombination protein
AAQM_1214	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
AAQM_1216	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
AAQM_1223	ENOG4105C9X	ppx gppa phosphatase
AAQM_1225	ENOG4105C7K	acetolactate synthase
AAQM_1226	ENOG4108ZP8	Acetolactate synthase small subunit
AAQM_1227	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AAQM_1228	ENOG4105CNU	cell division protein FtsK
AAQM_1230	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
AAQM_1231	ENOG4105CHH	sulfate transporter
AAQM_1235	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
AAQM_1237	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
AAQM_1238	ENOG4108VYJ	response regulator receiver protein
AAQM_1239	ENOG4105CBS	Chea signal transduction histidine kinase
AAQM_1240	ENOG4105BZU	Histidine kinase
AAQM_1241	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
AAQM_1242	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
AAQM_1246	ENOG4108EU4	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AAQM_1256	ENOG4105C9U	ATP-dependent DNA helicase RecQ
AAQM_1257	ENOG4108EU4	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AAQM_1258	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
AAQM_1259	ENOG4105E0C	molybdate abc transporter
AAQM_1261	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
AAQM_1262	ENOG4105F4R	Transcriptional regulator mode
AAQM_1266	ENOG4105DGW	oligopeptidase A
AAQM_1267	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
AAQM_1268	ENOG4105CSA	Coproporphyrinogen iii oxidase
AAQM_1269	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
AAQM_1270	ENOG4105CFH	Aspartokinase
AAQM_1273	ENOG4105EEI	dihydropteroate synthase
AAQM_1275	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AAQM_1276	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
AAQM_1278	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
AAQM_1284	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AAQM_1286	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
AAQM_1290	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
AAQM_1291	ENOG4105D9Q	decarboxylase (Beta subunit)
AAQM_1292	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
AAQM_1320	ENOG4105CIY	formyltetrahydrofolate deformylase
AAQM_1321	ENOG4105C6K	Malic enzyme
AAQM_1324	ENOG4105E2X	shikimate dehydrogenase
AAQM_1337	ENOG4105EYG	tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site (By similarity)
AAQM_1340	ENOG4105CPC	Aldo Keto reductase
AAQM_1345	ENOG4105EHG	Permease protein
AAQM_1346	ENOG4108JJB	ABC transporter
AAQM_1348	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
AAQM_1355	ENOG4105I08	Pseudouridine synthase
AAQM_1356	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
AAQM_1357	ENOG4105BZU	Histidine kinase
AAQM_1360	ENOG4105EBA	Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity)
AAQM_1361	ENOG4105JSC	dimethylmenaquinone methyltransferase
AAQM_1365	ENOG4105YES	addiction module antidote protein
AAQM_1368	ENOG4105EYH	Exonuclease
AAQM_1371	ENOG4105M15	transport protein ExbD
AAQM_1372	ENOG4105M8K	biopolymer transport protein
AAQM_1374	ENOG4105D05	Receptor
AAQM_1380	ENOG4107QX8	SPFH domain, Band 7 family protein
AAQM_1382	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AAQM_1385	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
AAQM_1389	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
AAQM_1390	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
AAQM_1391	ENOG4105D52	delta-aminolevulinic acid dehydratase
AAQM_1393	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AAQM_1396	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
AAQM_1397	ENOG4105DBV	ornithine carbamoyltransferase
AAQM_1398	ENOG4105D4P	Coproporphyrinogen iii oxidase
AAQM_1400	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
AAQM_1402	ENOG4105C4K	Nad synthetase
AAQM_1406	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
AAQM_1407	ENOG41084AD	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
AAQM_1408	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
AAQM_1409	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
AAQM_1466	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
AAQM_1468	ENOG4105DF6	Fe-S oxidoreductase
AAQM_1469	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
AAQM_1473	ENOG4105C2M	dna polymerase I
AAQM_1474	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
AAQM_1475	ENOG4105BZU	Histidine kinase
AAQM_1476	ENOG4105BZU	Histidine kinase
AAQM_1477	ENOG4108IUZ	ABC transporter
AAQM_1478	ENOG4105K8N	protein family UPF0079, ATPase
AAQM_1479	ENOG4107QYG	anthranilate phosphoribosyltransferase
AAQM_1481	ENOG4105D05	Receptor
AAQM_1483	ENOG4105CDH	Citrulline--aspartate ligase
AAQM_1488	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
AAQM_1489	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
AAQM_1490	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
AAQM_1494	ENOG4105C5X	domain protein
AAQM_1497	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
AAQM_1498	ENOG4105CRE	cytochrome C
AAQM_1499	ENOG4105ETX	regulatoR
AAQM_1501	ENOG4105CIN	aminoacyl-histidine dipeptidase
AAQM_1505	ENOG4107YTP	response regulator receiver protein
AAQM_1508	ENOG4105DVC	DnaJ domain protein
AAQM_1509	ENOG4105KNI	merR family transcriptional Regulator
AAQM_1512	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
AAQM_1514	ENOG4105D06	uba thif-type nad fad binding protein
AAQM_1515	ENOG4108M8H	domain protein
AAQM_1517	ENOG4105C8P	)-transporter
AAQM_1518	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
AAQM_1520	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
AAQM_1521	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
AAQM_1523	ENOG4105D49	3-dehydroquinate synthase
AAQM_1525	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
AAQM_1527	ENOG4105DY9	regulatoR
AAQM_1530	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
AAQM_1534	ENOG4105I03	Flagellin
AAQM_1534	ENOG4105I03	Flagellin
AAQM_1538	ENOG4108STX	response regulator
AAQM_1542	ENOG4105BZ1	(ABC) transporter
AAQM_1543	ENOG4105DSF	transport protein
AAQM_1545	ENOG4105BZU	Histidine kinase
AAQM_1546	ENOG4105K63	Thioredoxin
AAQM_1547	ENOG4105D3R	alkyl hydroperoxide reductase
AAQM_1549	ENOG4105BZU	Histidine kinase
AAQM_1551	ENOG4105D17	glycoside hydrolase, family 3 domain protein
AAQM_1555	ENOG4105DAA	L-lactate
AAQM_1565	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
AAQM_1566	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
AAQM_1567	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
AAQM_1568	ENOG4108ZT0	50S ribosomal protein l17
AAQM_1569	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AAQM_1570	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
AAQM_1571	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
AAQM_1572	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AAQM_1573	ENOG41067V7	50S ribosomal protein L36
AAQM_1576	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
AAQM_1577	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
AAQM_1578	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AAQM_1582	ENOG4105NBK	UPF0345 protein
AAQM_1583	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
AAQM_1587	ENOG4105CNI	cell division protein FtsW
AAQM_1588	ENOG4105C34	Pseudouridine synthase
AAQM_1589	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
AAQM_1590	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
AAQM_1591	ENOG4105CAK	Cell division ATP-binding protein ftsE
AAQM_1594	ENOG4108UPT	UPF0178 protein
AAQM_1596	ENOG4105C5H	ABC transporter
AAQM_1602	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
AAQM_1603	ENOG4105C25	Primosomal protein n'
AAQM_1609	ENOG4105C45	hydrogenase expression formation protein (HypE)
AAQM_1611	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
AAQM_1613	ENOG4105CQS	hydrogenase expression formation protein HypD
AAQM_1614	ENOG4105WRB	Hydrogenase assembly chaperone hypC hupF
AAQM_1615	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
AAQM_1619	ENOG4107XQ1	cobalamin (vitamin B12) biosynthesis CbiM protein
AAQM_1621	ENOG4105C8Q	Methyl-accepting chemotaxis
AAQM_1623	ENOG4105CBX	hi0933 family
AAQM_1626	ENOG4105VCH	membrane
AAQM_1628	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
AAQM_1631	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
AAQM_1634	ENOG41080XP	Cbs domain
AAQM_1642	ENOG4105DPX	Hydrogenase, large subunit
AAQM_1643	ENOG4105E3S	small subunit
AAQM_1647	ENOG4107QIJ	Aconitate hydratase 2
AAQM_1650	ENOG4108IQE	Amp-dependent synthetase and ligase
AAQM_1651	ENOG4105CHU	acetyl-coa acetyltransferase
AAQM_1653	ENOG4107QPN	acyl-Coa dehydrogenase
AAQM_1656	ENOG4105BZU	Histidine kinase
AAQM_1660	ENOG4105CDY	transcriptional regulatory protein
AAQM_1661	ENOG4105DR5	peptidase
AAQM_1662	ENOG410903C	(LipO)protein
AAQM_1665	ENOG4108URH	decarboxylase
AAQM_1666	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
AAQM_1675	ENOG4105C94	Transporter
AAQM_1676	ENOG4108ISG	Major Facilitator
AAQM_1680	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
AAQM_1681	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
AAQM_1684	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
AAQM_1685	ENOG4105C8Y	Acetylornithine aminotransferase
AAQM_1690	ENOG4105C1J	atp-dependent rna helicase
AAQM_1691	ENOG4105DDY	UPF0142 protein ycaO
AAQM_1695	ENOG4105C8Q	Methyl-accepting chemotaxis
AAQM_1696	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
AAQM_1697	ENOG4105DF3	Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds (By similarity)
AAQM_1699	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
AAQM_1701	ENOG4107S7U	Sulfide dehydrogenase
AAQM_1703	ENOG4105C3J	Cysteine desulfurase
AAQM_1705	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
AAQM_1707	ENOG4105QAX	Iron-sulfur
AAQM_1710	ENOG4108SBI	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
AAQM_1714	ENOG4108MRH	transcriptional regulatory protein
AAQM_1715	ENOG4105K3M	)-transporter
AAQM_1718	ENOG4108KS2	transglutaminase domain protein
AAQM_1721	ENOG4105C1Y	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis (By similarity)
AAQM_1722	ENOG4105EM7	Selenocysteine-specific translation elongation factor
AAQM_1728	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AAQM_1729	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
AAQM_1730	ENOG4105BZU	Histidine kinase
AAQM_1731	ENOG4105BZU	Histidine kinase
AAQM_1739	ENOG41090R7	Ferric uptake
AAQM_1749	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AAQM_1750	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AAQM_1753	ENOG4105M8K	biopolymer transport protein
AAQM_1754	ENOG4105M15	transport protein ExbD
AAQM_1756	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
AAQM_1758	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
AAQM_1759	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
AAQM_1761	ENOG4108VAU	general secretion pathway protein G
AAQM_1762	ENOG4105CDU	Replicative dna helicase
AAQM_1764	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
AAQM_1767	ENOG4105CRK	lysyL-tRNA synthetase
AAQM_1768	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
AAQM_1770	ENOG4105CRQ	synthase (Component I)
AAQM_1771	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
AAQM_1772	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
AAQM_1774	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
AAQM_1775	ENOG410692R	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
AAQM_1777	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
AAQM_1779	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
AAQM_1782	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
AAQM_1783	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
AAQM_1784	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
AAQM_1785	ENOG4105C3F	Signal peptidase i
AAQM_1786	ENOG4108YZG	isomerase
AAQM_1794	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
AAQM_1797	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
AAQM_1798	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
AAQM_1799	ENOG4105CUZ	uba thif-type nad fad binding protein
AAQM_1801	ENOG4105CH7	arginosuccinase
AAQM_1802	ENOG4105FQT	
AAQM_1805	ENOG4105BZU	Histidine kinase
AAQM_1807	ENOG4105CJW	magnesium transporter
AAQM_1809	ENOG4107RIU	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins (By similarity)
AAQM_1812	ENOG4105C3K	feS assembly ATPase SufC
AAQM_1814	ENOG4105C9B	Cysteine desulfurase
AAQM_1815	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
AAQM_1818	ENOG4105C8Q	Methyl-accepting chemotaxis
AAQM_1820	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
AAQM_1821	ENOG4105BZU	Histidine kinase
AAQM_1823	ENOG4105KPY	Small multidrug resistance protein
AAQM_1829	ENOG4105CNG	UPF0061 protein
AAQM_1830	ENOG4105BZU	Histidine kinase
AAQM_1831	ENOG4105C8Q	Methyl-accepting chemotaxis
AAQM_1832	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
AAQM_1838	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
AAQM_1839	ENOG410901F	(LipO)protein
AAQM_1844	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
AAQM_1845	ENOG4107RDB	Major Facilitator
AAQM_1847	ENOG4106TD9	Diguanylate cyclase
AAQM_1848	ENOG4105EUJ	GTP cyclohydrolase i
AAQM_1849	ENOG4105D7N	magnesium and cobalt transport protein CorA
AAQM_1850	ENOG4105D7Q	type ii secretion system
AAQM_1851	ENOG4107QHF	type ii secretion system protein e
AAQM_1854	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
AAQM_1855	ENOG4105C0P	Mg chelatase subunit ChlI
AAQM_1857	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
AAQM_1858	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
AAQM_1859	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
AAQM_1861	ENOG4105CSR	polyphosphate kinase 2
AAQM_1862	ENOG4105CSR	polyphosphate kinase 2
AAQM_1864	ENOG4105VCQ	rubredoxin
AAQM_1867	ENOG4105DFP	Integrase
AAQM_1886	ENOG4108VWS	Yaeq family
AAQM_1890	ENOG4105C28	cystathionine
AAQM_1894	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AAQM_1896	ENOG4105D7X	high-affinity nickel-transporter
AAQM_1899	ENOG4105D65	subunit l
AAQM_1900	ENOG4108ZE9	Monovalent cation H antiporter subunit C
AAQM_1901	ENOG4107R4Z	monovalent cation h antiporter subunit d
AAQM_1902	ENOG4105SC1	monovalent cation H antiporter subunit E
AAQM_1903	ENOG4105W4C	monovalent cation H antiporter subunit F
AAQM_1904	ENOG4105KJM	monovalent cation h antiporter subunit g
AAQM_1905	ENOG4105CHR	reductase
AAQM_1913	ENOG41084IH	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
AAQM_1915	ENOG4105D64	Mechanosensitive ion channel
AAQM_1921	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
AAQM_1924	ENOG4105C58	cytochrome c oxidase accessory protein ccog
AAQM_1925	ENOG4105BZU	Histidine kinase
AAQM_1926	ENOG4107VQW	regulatoR
AAQM_1928	ENOG4107QKV	phosphomannomutase
AAQM_1934	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
AAQM_1937	ENOG4105CE1	Ferrous iron transport protein b
AAQM_1940	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
AAQM_1941	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
AAQM_1942	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
AAQM_1943	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
AAQM_1944	ENOG4105F4G	Membrane
AAQM_1946	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
AAQM_1955	ENOG41082XB	radical SAM domain protein
AAQM_1956	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
AAQM_1958	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
AAQM_1960	ENOG4105Z2P	Protein of unknown function (DUF465)
AAQM_1961	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
AAQM_1963	ENOG4105VB9	50S ribosomal protein l28
AAQM_1967	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
AAQM_1968	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
AAQM_1969	ENOG4105DKP	glycosyl transferase, family 9
AAQM_1972	ENOG4107R51	Glycosyl transferase, family 2
AAQM_1975	ENOG4105CPK	Glycosyl transferase (Group 1
AAQM_1978	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
AAQM_1980	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
AAQM_1982	ENOG4107S6X	Glycosyl transferase, family 2
AAQM_1984	ENOG4108RJ9	Glycosyl transferase, family 2
AAQM_1985	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
AAQM_1987	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
AAQM_1988	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
AAQM_1992	ENOG4105DKP	glycosyl transferase, family 9
AAQM_1994	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
AAQM_1996	ENOG4105BZ8	glutamate synthase
AAQM_1997	ENOG4105CBC	glutamate synthase
AAQM_2011	ENOG4105C5E	polysaccharide biosynthesis protein
AAQM_2012	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
AAQM_2013	ENOG4105ESV	Glycosyl transferase, family 4
AAQM_2018	ENOG4105CMR	udp-glucose 4-epimerase
AAQM_2026	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
AAQM_2029	ENOG4105C7K	acetolactate synthase
AAQM_2030	ENOG4105FAW	cDP-glucose 4,6-dehydratase
AAQM_2031	ENOG4105EJZ	Glucose-1-phosphate cytidylyltransferase
AAQM_2032	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
AAQM_2033	ENOG4105J5G	Transferase hexapeptide repeat containing protein
AAQM_2034	ENOG4107R5Z	Oxidoreductase domain protein
AAQM_2035	ENOG4107QQG	Dehydrogenase
AAQM_2036	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
AAQM_2037	ENOG4105M7K	Involved in the transcription termination process (By similarity)
AAQM_2038	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
AAQM_2041	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
AAQM_2046	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
AAQM_2049	ENOG4105GVR	general secretion pathway protein D
AAQM_2050	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
AAQM_2051	ENOG4105DX0	Hemolysin A
AAQM_2052	ENOG4105DTN	riboflavin biosynthesis protein ribF
AAQM_2053	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
AAQM_2054	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AAQM_2056	ENOG4105CQB	FAD linked oxidase domain protein
AAQM_2057	ENOG4107S2Z	UPF0761 membrane protein
AAQM_2067	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AAQM_2068	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
AAQM_2069	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
AAQM_2072	ENOG4105DJG	MaoC domain protein dehydratase
AAQM_2076	ENOG4105C8Q	Methyl-accepting chemotaxis
AAQM_2077	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
AAQM_2078	ENOG4107XC4	flavin reductase domain protein, FMN-binding
AAQM_2084	ENOG4105D7B	Flagellar biosynthesis protein flha
AAQM_2085	ENOG4105DTJ	flagellar hook-associated protein
AAQM_2086	ENOG4108JIR	Flagellum-specific ATP synthase
AAQM_2088	ENOG4105D00	flagellar biosynthetic protein flhB
AAQM_2091	ENOG4108ZC9	flagellar basal-body rod protein flgc
AAQM_2092	ENOG41084DA	flagellar hook-basal body complex protein fliE
AAQM_2094	ENOG4107R21	site-determining protein
AAQM_2095	ENOG4105FZW	flagellar biosynthesis regulator FlhF
AAQM_2100	ENOG4108217	motA TolQ ExbB proton channel
AAQM_2101	ENOG4105DD5	Flagellar motor switch protein
AAQM_2105	ENOG4105BZE	flagellar hook protein, FlgE
AAQM_2106	ENOG4108JQA	flagellar
AAQM_2108	ENOG4105DD5	Flagellar motor switch protein
AAQM_2110	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
AAQM_2111	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
AAQM_2112	ENOG4105Q75	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
AAQM_2113	ENOG4105CGA	flagellar basal-body rod protein FlgG
AAQM_2116	ENOG4105CGA	flagellar basal-body rod protein FlgG
AAQM_2119	ENOG4105V3S	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
AAQM_2121	ENOG4105K5M	30s ribosomal protein S16
AAQM_2122	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AAQM_2126	ENOG4105EGD	dinuclear metal center protein, YbgI family
AAQM_2127	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
AAQM_2129	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
AAQM_2131	ENOG4105CFP	Peptidase U32
AAQM_2132	ENOG41080BE	Methyl-accepting chemotaxis sensory transducer
AAQM_2132	ENOG41080BE	Methyl-accepting chemotaxis sensory transducer
AAQM_2133	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
AAQM_2134	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
AAQM_2135	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
AAQM_2136	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
AAQM_2137	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
AAQM_2138	ENOG4105F27	Major Facilitator
AAQM_2146	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AAQM_2147	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AAQM_2148	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
AAQM_2149	ENOG4108VZM	50s ribosomal protein L10
AAQM_2150	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
AAQM_2151	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
AAQM_2152	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
AAQM_2155	ENOG41086AR	50S ribosomal protein L33
AAQM_2156	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
AAQM_2162	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
AAQM_2163	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
AAQM_2165	ENOG4108JQC	penicillin-binding protein 1A
AAQM_2166	ENOG4105C5F	glutamine synthetase
AAQM_2169	ENOG4108ZEX	molybdopterin converting factor, subunit 2
AAQM_2171	ENOG4108XUR	Pfam:DUF178
AAQM_2172	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
AAQM_2174	ENOG4105CNI	cell division protein FtsW
AAQM_2175	ENOG4105CJN	penicillin-binding protein
AAQM_2176	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
AAQM_2184	ENOG4105DDQ	anthranilate synthase
AAQM_2187	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
AAQM_2188	ENOG4105BZU	Histidine kinase
AAQM_2195	ENOG4105BZU	Histidine kinase
AAQM_2199	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
AAQM_2202	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
AAQM_2203	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
AAQM_2205	ENOG4107QYE	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
AAQM_2206	ENOG4105C7B	Threonine dehydratase
AAQM_2207	ENOG4107WJT	it plays a direct role in the translocation of protons across the membrane (By similarity)
AAQM_2208	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
AAQM_2209	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
AAQM_2210	ENOG4105CAS	nag kinase
AAQM_2211	ENOG4107QID	Threonine synthase
AAQM_2212	ENOG4105DQV	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity)
AAQM_2213	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
AAQM_2216	ENOG4107YV6	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
AAQM_2218	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
AAQM_2219	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
AAQM_2221	ENOG4107SPB	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
AAQM_2222	ENOG4105CHR	reductase
AAQM_2223	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
AAQM_2224	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
AAQM_2225	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
AAQM_2226	ENOG4105K59	histidine triad (HIT) protein
AAQM_2227	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
AAQM_2228	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
AAQM_2229	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
AAQM_2230	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
AAQM_2231	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
AAQM_2232	ENOG4108JQ1	Dehydrogenase
AAQM_2233	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
AAQM_2234	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
AAQM_2235	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
AAQM_2236	ENOG4105MGB	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
AAQM_2237	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
AAQM_2239	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
AAQM_2241	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AAQM_2244	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
AAQM_2246	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
AAQM_2248	ENOG4105YIC	Major outer membrane protein
AAQM_2250	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
AAQM_2258	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
AAQM_2259	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
AAQM_2260	ENOG4107Z7S	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
AAQM_2261	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
AAQM_2262	ENOG4105C4R	Atp-dependent dna helicase
AAQM_2263	ENOG4105DUM	transcriptional regulator, lysR family
AAQM_2264	ENOG4105N5T	Radical SAM Protein
AAQM_2265	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
AAQM_2266	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
AAQM_2267	ENOG4105C3M	thioredoxin reductase
AAQM_2268	ENOG4105K63	Thioredoxin
AAQM_2269	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
AAQM_2274	ENOG4107TT5	NLP P60 protein
AAQM_2275	ENOG4107TT5	NLP P60 protein
AAQM_2278	ENOG4107YJQ	MAF-like protein
AAQM_2279	ENOG4105CA0	peroxidase
AAQM_2280	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
AAQM_2281	ENOG4105CIH	Imidazole acetol-phosphate transaminase
AAQM_2282	ENOG4105CQC	Prephenate dehydratase
AAQM_2283	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
AAQM_2284	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
AAQM_2285	ENOG4105CP7	Triose-phosphate isomerase
AAQM_2286	ENOG4105BZA	Phosphoglycerate kinase
AAQM_2287	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
AAQM_2288	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
AAQM_2290	ENOG4105C75	arginyL-tRNA synthetase
AAQM_2291	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
AAQM_2292	ENOG4105WMR	Protein CrcB homolog
AAQM_2293	ENOG4105E9Q	Acyl-transferase
AAQM_2295	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
AAQM_2296	ENOG4105VR9	phosphoribosylformylglycinamidine synthase
AAQM_2297	ENOG4105C8V	SAICAR synthetase
AAQM_2298	ENOG4105CN1	protease
AAQM_2301	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
AAQM_2304	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AAQM_2318	ENOG4105C01	Dihydroxy-acid dehydratase
AAQM_2319	ENOG4105C0H	protease
AAQM_2323	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
AAQM_2324	ENOG4105CGD	Nad-dependent epimerase dehydratase
AAQM_2325	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
AAQM_2329	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
AAQM_2331	ENOG4105CIH	Imidazole acetol-phosphate transaminase
AAQM_2332	ENOG4107XPA	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
AAQM_2334	ENOG41081FY	multiple antibiotic resistance (MarC)-related
AAQM_2335	ENOG4105F0R	Cytidylyltransferase
AAQM_2336	ENOG4108K7V	UPF0284 protein
AAQM_2339	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
AAQM_2340	ENOG4105K63	Thioredoxin
AAQM_2341	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
AAQM_2344	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
AAQM_2347	ENOG4105BZU	Histidine kinase
AAQM_2348	ENOG4105DJ4	phosphatidylserine decarboxylase
AAQM_2350	ENOG4105CA3	membrane-bound lytic murein transglycosylase
AAQM_2352	ENOG4105CFG	Acts as a chaperone (By similarity)
AAQM_2353	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AAQM_2357	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AAQM_2359	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
AAQM_2361	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
AAQM_2362	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
AAQM_2363	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
AAQM_2364	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
AAQM_2366	ENOG4105CQR	helicase
AAQM_2367	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
AAQM_2368	ENOG4105I03	Flagellin
AAQM_2369	ENOG4105I03	Flagellin
AAQM_2374	ENOG4105F0R	Cytidylyltransferase
AAQM_2375	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
AAQM_2376	ENOG4105C5E	polysaccharide biosynthesis protein
AAQM_2381	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
AAQM_2384	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
AAQM_2386	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
AAQM_2387	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
AAQM_2390	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
AAQM_2393	ENOG4105D4A	Cell wall formation (By similarity)
AAQM_2394	ENOG4105E63	Pfam:DUF178
AAQM_2396	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AAQM_2397	ENOG4105C8S	subunit m
AAQM_2398	ENOG4105D65	subunit l
AAQM_2399	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AAQM_2401	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AAQM_2402	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
AAQM_2406	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AAQM_2407	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AAQM_2408	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AAQM_2409	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AAQM_2410	ENOG4105DHM	ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis (By similarity)
AAQM_2415	ENOG4105CHH	sulfate transporter
AAQM_2416	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
AAQM_2418	ENOG4105C8J	)-transporter
AAQM_2420	ENOG4105WPN	DNA integration recombination invertion protein
AAQM_2422	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
AAQM_2423	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AAQM_2424	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
AAQM_2428	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
AAQM_2430	ENOG4105CGK	Exodeoxyribonuclease III
AAQM_2432	ENOG4105C4R	Atp-dependent dna helicase
AAQM_2439	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
AAQM_2444	ENOG4105C58	cytochrome c oxidase accessory protein ccog
AAQM_2445	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
AAQM_2446	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
AAQM_2452	ENOG4105C0B	DNA polymerase III (alpha subunit)
AAQM_2453	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
AAQM_2456	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
AAQM_2463	ENOG4105HFZ	Membrane
AAQM_2464	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
AAQM_2466	ENOG4105NU9	Preprotein translocase subunit SecG
AAQM_2468	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
AAQM_2469	ENOG4107VCP	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
AAQM_2471	ENOG4105D8G	Major Facilitator superfamily
AAQM_2472	ENOG4105EGS	Mechanosensitive ion channel
AAQM_2474	ENOG410802Z	Protein of unknown function (DUF328)
AAQM_2475	ENOG4105K5B	UPF0225 protein
AAQM_2480	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
AAQM_2481	ENOG4105C26	Dehydrogenase
AAQM_2482	ENOG4105C7K	acetolactate synthase
AAQM_2483	ENOG4108V0P	LemA family
AAQM_2486	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
AAQM_2489	ENOG4105C2C	drug resistance transporter, Bcr CflA
AAQM_2490	ENOG4105C8Q	Methyl-accepting chemotaxis
AAQM_2497	ENOG4105CBX	hi0933 family
AAQM_2501	ENOG4105C6T	cysteine synthase
AAQM_2504	ENOG4105C11	sulfate adenylyltransferase), subunit 2
AAQM_2505	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
AAQM_2506	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
AAQM_2510	ENOG4105C9B	Cysteine desulfurase
AAQM_2511	ENOG4107RN3	metallophosphoesterase
AAQM_2512	ENOG4107Y70	Heat shock protein
AAQM_2516	ENOG4108IJ6	ABC transporter
AAQM_2518	ENOG4108I5D	sulfate abc transporter
AAQM_2519	ENOG4105BZU	Histidine kinase
AAQM_2520	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
AAQM_2526	ENOG4105CI3	gtp-binding protein typa
AAQM_2527	ENOG4105E0M	Sulfatase
AAQM_2530	ENOG41080IJ	Diacylglycerol kinase
AAQM_2536	ENOG41066VF	YeeE YedE family protein
AAQM_2538	ENOG4107R2U	Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity)
AAQM_2539	ENOG4105CSV	Glutaminase
AAQM_2540	ENOG4105EN6	Membrane
AAQM_2542	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
AAQM_2543	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)