locus-tag	class	description
FM022_00010	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
FM022_00015	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
FM022_00020	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
FM022_00025	ENOG4105C3M	thioredoxin reductase
FM022_00030	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
FM022_00040	ENOG4105W39	Membrane
FM022_00045	ENOG4108BSC	Methyltransferase
FM022_00050	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
FM022_00055	ENOG4105E0C	molybdate abc transporter
FM022_00065	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
FM022_00070	ENOG4105F4R	Transcriptional regulator mode
FM022_00095	ENOG4105EI2	Pseudouridine synthase
FM022_00100	ENOG4107QTF	adenylosuccinate lyase
FM022_00105	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
FM022_00130	ENOG4105EIY	sodium-type flagellar protein motY
FM022_00145	ENOG4105KVH	Transcriptional regulator
FM022_00150	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
FM022_00155	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
FM022_00170	ENOG4105DAA	L-lactate
FM022_00180	ENOG4105BZU	Histidine kinase
FM022_00185	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
FM022_00190	ENOG4107QR9	Iron-sulfur cluster binding protein
FM022_00195	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
FM022_00200	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
FM022_00205	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
FM022_00210	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
FM022_00215	ENOG4105C1J	atp-dependent rna helicase
FM022_00220	ENOG4105CJ3	phosphate transporter
FM022_00230	ENOG4105CAQ	asparagine synthetase
FM022_00245	ENOG4108YXA	Membrane
FM022_00250	ENOG4105D1H	recombination factor protein RarA
FM022_00260	ENOG4105C2X	Arabinose 5-phosphate isomerase
FM022_00265	ENOG4105CN5	Metallo-Beta-Lactamase
FM022_00270	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
FM022_00275	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
FM022_00290	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
FM022_00295	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
FM022_00300	ENOG4105VFU	Rna-binding protein
FM022_00365	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
FM022_00370	ENOG41084M8	50s ribosomal protein L35
FM022_00375	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
FM022_00395	ENOG41080AZ	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
FM022_00400	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
FM022_00405	ENOG410813J	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
FM022_00410	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
FM022_00415	ENOG4108317	Binds directly to 16S ribosomal RNA (By similarity)
FM022_00420	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
FM022_00430	ENOG4105PWN	phosphate abc transporter
FM022_00435	ENOG4108M8H	domain protein
FM022_00440	ENOG4105C8U	phosphate abc transporter
FM022_00445	ENOG4105E2Z	phosphate ABC transporter (Permease
FM022_00450	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
FM022_00465	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
FM022_00470	ENOG4105BZU	Histidine kinase
FM022_00475	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
FM022_00480	ENOG4108UJD	30S ribosomal protein S9
FM022_00490	ENOG4107XGZ	Hydrolase
FM022_00520	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
FM022_00535	ENOG4105DZ1	carboxypeptidase
FM022_00555	ENOG4105CM2	brancheD-chain amino acid aminotransferase
FM022_00570	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
FM022_00580	ENOG4105D1F	ATP-binding protein
FM022_00585	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
FM022_00595	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
FM022_00605	ENOG4108ZAI	phosphatidylglycerophosphatase a
FM022_00610	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
FM022_00620	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
FM022_00625	ENOG4105CYE	ATP phosphoribosyltransferase regulatory subunit
FM022_00630	ENOG4107UUH	Aminotransferase
FM022_00635	ENOG4108YYC	ycei family
FM022_00640	ENOG4105GVJ	transcriptional regulator
FM022_00645	ENOG4108YYC	ycei family
FM022_00660	ENOG4105C2I	pirin domain protein
FM022_00665	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
FM022_00670	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
FM022_00675	ENOG41084QV	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
FM022_00680	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
FM022_00685	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
FM022_00690	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
FM022_00695	ENOG4105KY5	gCN5-related N-acetyltransferase
FM022_00705	ENOG4105DFH	Transport of potassium into the cell (By similarity)
FM022_00725	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
FM022_00730	ENOG41082DI	50s ribosomal protein l31
FM022_00740	ENOG4105C2N	RNA methyltransferase TrmH family group 3
FM022_00750	ENOG4105CHM	Aminotransferase
FM022_00755	ENOG4105D6E	homoserine dehydrogenase
FM022_00765	ENOG4105KNE	Phosphatidate cytidylyltransferase
FM022_00770	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
FM022_00785	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
FM022_00790	ENOG4108ZJT	translation initiation factor, Sui1
FM022_00795	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
FM022_00800	ENOG4105VF7	tolerance protein
FM022_00805	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
FM022_00845	ENOG4107QSA	Oxaloacetate decarboxylase
FM022_00860	ENOG4105C8Q	Methyl-accepting chemotaxis
FM022_00865	ENOG4108F3G	Type I restriction-modification system, R subunit
FM022_00880	ENOG4105CV1	Transketolase (EC 2.2.1.1)
FM022_00890	ENOG41067MG	lrgb family
FM022_00900	ENOG4105Z6B	inner membrane protein yjfl
FM022_00905	ENOG4105CK2	sodium dicarboxylate symporter
FM022_00925	ENOG4108HPI	phosphatidate Cytidylyltransferase
FM022_00935	ENOG4105CEY	Amp-dependent synthetase and ligase
FM022_00940	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
FM022_00955	ENOG41069AG	Ankyrin repeat
FM022_00960	ENOG4108YZA	Nitrogen regulatory protein pii
FM022_00965	ENOG4105EKE	dihydroorotase
FM022_00970	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
FM022_00975	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
FM022_00985	ENOG4105VS8	Flagellar biosynthetic protein fliq
FM022_01010	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
FM022_01015	ENOG4105BZE	flagellar hook protein, FlgE
FM022_01020	ENOG4105DTS	flagellar hook-associated
FM022_01040	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
FM022_01045	ENOG4107R03	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
FM022_01060	ENOG4105D6U	Sodium Glutamate Symporter
FM022_01065	ENOG4105GSH	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
FM022_01075	ENOG4105EAC	phosphoserine phosphatase
FM022_01085	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
FM022_01090	ENOG4105DRB	nucleoside-specific channel-forming protein
FM022_01095	ENOG4105KUZ	arsenate reductase
FM022_01100	ENOG410855J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
FM022_01105	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
FM022_01115	ENOG4105CHM	Aminotransferase
FM022_01125	ENOG4105DFU	Cell wall formation (By similarity)
FM022_01140	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
FM022_01145	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
FM022_01150	ENOG410821Z	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum (By similarity)
FM022_01160	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
FM022_01165	ENOG4108UUM	single-stranded DNA-binding protein
FM022_01170	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
FM022_01180	ENOG4105C8N	cysteinyl-tRNA synthetase
FM022_01185	ENOG4105CHV	Transcription elongation factor NusA
FM022_01195	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
FM022_01200	ENOG4105KB8	(LipO)protein
FM022_01210	ENOG4105DVY	radical SAM domain protein
FM022_01225	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
FM022_01230	ENOG41082UM	UPF0102 protein
FM022_01235	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
FM022_01260	ENOG4105CXT	aspartate transcarbamylase
FM022_01285	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
FM022_01290	ENOG4108VKG	metal-dependent hydrolase
FM022_01295	ENOG4105EJ9	Membrane
FM022_01320	ENOG4105C5I	Dehydrogenase
FM022_01330	ENOG4105CR4	methylisocitrate lyase
FM022_01335	ENOG4105BZN	citrate synthase
FM022_01340	ENOG4108I0Z	Aconitate hydratase
FM022_01345	ENOG4105C7F	AcnD-accessory protein PrpF
FM022_01355	ENOG4105CHJ	isochorismatase hydrolase
FM022_01365	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
FM022_01375	ENOG4107QMP	dna polymerase iii subunits gamma and tau
FM022_01380	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
FM022_01385	ENOG4105D82	Glutamate dehydrogenase
FM022_01390	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
FM022_01395	ENOG4105D3R	alkyl hydroperoxide reductase
FM022_01405	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
FM022_01415	ENOG4105YQ2	50s ribosomal protein l32
FM022_01420	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
FM022_01425	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
FM022_01445	ENOG4105E33	succinate dehydrogenase
FM022_01450	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
FM022_01455	ENOG4108S24	Fumarate reduCtase
FM022_01460	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
FM022_01465	ENOG4105C8S	subunit m
FM022_01470	ENOG4105D65	subunit l
FM022_01475	ENOG41080EA	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
FM022_01480	ENOG4107UFS	subunit j
FM022_01490	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
FM022_01500	ENOG4105BZN	citrate synthase
FM022_01510	ENOG4105GKE	subunit e
FM022_01515	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
FM022_01520	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
FM022_01525	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FM022_01535	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
FM022_01540	ENOG4107XM3	UPF0442 protein
FM022_01545	ENOG4105DWK	Membrane
FM022_01560	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
FM022_01570	ENOG4105C8Q	Methyl-accepting chemotaxis
FM022_01580	ENOG4105C31	Tryptophanyl-tRNA synthetase
FM022_01620	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
FM022_01650	ENOG4105PGM	cation diffusion facilitator family transporter
FM022_01655	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
FM022_01660	ENOG4105CRE	cytochrome C
FM022_01665	ENOG4105EAU	Plays a role in nitrite reduction (By similarity)
FM022_01670	ENOG4108W6G	cytochrome C
FM022_01680	ENOG4105BZU	Histidine kinase
FM022_01685	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
FM022_01705	ENOG4108ZMS	Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity)
FM022_01710	ENOG4105GXZ	Ferredoxin-type protein NapH
FM022_01715	ENOG4108BGM	Quinol dehydrogenase periplasmic component
FM022_01720	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
FM022_01725	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
FM022_01730	ENOG4105XDZ	Tripartite ATP-independent periplasmic transporter
FM022_01735	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
FM022_01745	ENOG4107VQW	regulatoR
FM022_01750	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
FM022_01755	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
FM022_01765	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
FM022_01770	ENOG4108I0Q	anthranilate phosphoribosyltransferase
FM022_01775	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
FM022_01780	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
FM022_01790	ENOG4108KA0	Inherit from COG: Phosphoesterase, DHHA1
FM022_01795	ENOG4105K4P	CoA-binding domain protein
FM022_01800	ENOG4105DHQ	Histidine kinase
FM022_01805	ENOG4105ETX	regulatoR
FM022_01810	ENOG4105EIN	peptidylprolyl cis-trans isomerase
FM022_01815	ENOG4105D2N	Aldolase
FM022_01830	ENOG4105SG9	biopolymer transport protein, ExbD
FM022_01835	ENOG4105M8K	biopolymer transport protein
FM022_01845	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
FM022_01850	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
FM022_01865	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
FM022_01870	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
FM022_01905	ENOG4105VIE	preprotein translocase, subunit YajC
FM022_01910	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
FM022_01915	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
FM022_01930	ENOG4108SEK	ompa motb domain protein
FM022_01945	ENOG4105C8T	Leucyl-tRNA synthetase
FM022_01955	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
FM022_01985	ENOG4108JA2	transcriptioN-repair coupling factor
FM022_02005	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
FM022_02015	ENOG4105CBX	hi0933 family
FM022_02020	ENOG4105C8Q	Methyl-accepting chemotaxis
FM022_02040	ENOG4105D48	metallophosphoesterase
FM022_02055	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
FM022_02060	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
FM022_02065	ENOG4108V3W	Chemotaxis protein, CheW
FM022_02070	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
FM022_02075	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
FM022_02080	ENOG41084FT	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
FM022_02090	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
FM022_02095	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
FM022_02105	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
FM022_02110	ENOG4107RN3	metallophosphoesterase
FM022_02135	ENOG4107XPZ	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
FM022_02150	ENOG4105ECY	inositol monophosphatase
FM022_02155	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
FM022_02160	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
FM022_02165	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
FM022_02170	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
FM022_02175	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
FM022_02185	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
FM022_02190	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
FM022_02195	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
FM022_02210	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
FM022_02220	ENOG4105BZU	Histidine kinase
FM022_02225	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
FM022_02240	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
FM022_02250	ENOG410624X	efflux transporter, rnd family, mfp subunit
FM022_02280	ENOG4105J9X	quinohemoprotein amine dehydrogenase gamma subunit
FM022_02290	ENOG4105BZ1	(ABC) transporter
FM022_02305	ENOG4105BZU	Histidine kinase
FM022_02310	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
FM022_02315	ENOG4105ECP	epimerase
FM022_02340	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
FM022_02355	ENOG4105CDV	Ompa motb domain protein
FM022_02360	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
FM022_02370	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
FM022_02375	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
FM022_02380	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FM022_02385	ENOG4105DC7	peptidase M24
FM022_02390	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
FM022_02395	ENOG4107SYB	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
FM022_02410	ENOG4108IJ2	phosphate acetyltransferase
FM022_02415	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
FM022_02430	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
FM022_02450	ENOG4107QN1	sodium solute
FM022_02460	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
FM022_02470	ENOG4107QN1	sodium solute
FM022_02485	ENOG4105BZU	Histidine kinase
FM022_02530	ENOG4105CEV	competence damage-inducible protein
FM022_02535	ENOG4107RSR	Malate quinone oxidoreductase
FM022_02540	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
FM022_02555	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
FM022_02580	ENOG4105BZU	Histidine kinase
FM022_02595	ENOG4105CPC	Aldo Keto reductase
FM022_02600	ENOG4105CJ3	phosphate transporter
FM022_02605	ENOG4105C8Q	Methyl-accepting chemotaxis
FM022_02615	ENOG4105C8Q	Methyl-accepting chemotaxis
FM022_02645	ENOG4107YD3	Thioesterase
FM022_02655	ENOG4105C2Y	STE24 endopeptidase EC 3.4.24.84
FM022_02660	ENOG4105CGY	Dna recombination protein
FM022_02670	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
FM022_02680	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
FM022_02700	ENOG4105CE9	30S ribosomal protein S2
FM022_02705	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
FM022_02710	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
FM022_02720	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
FM022_02725	ENOG4105BZU	Histidine kinase
FM022_02730	ENOG4105C59	p-type ATPase
FM022_02745	ENOG4108JQ7	(ABC) transporter
FM022_02750	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
FM022_02765	ENOG4107S90	membrAne
FM022_02770	ENOG4105FDK	ABC transporter
FM022_02780	ENOG4105QNR	S1 RNA binding domain protein
FM022_02785	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
FM022_02805	ENOG4105ENA	helicase
FM022_02815	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
FM022_02830	ENOG4107RDB	Major Facilitator
FM022_02835	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
FM022_02855	ENOG4105II7	pyrroline-5-carboxylate reductase
FM022_02860	ENOG410901F	(LipO)protein
FM022_02865	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
FM022_02890	ENOG4107SDU	Methyl-accepting chemotaxis
FM022_02940	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
FM022_02945	ENOG4105VG1	fes assembly suf system protein
FM022_02950	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
FM022_02955	ENOG4105C9B	Cysteine desulfurase
FM022_02965	ENOG4105C3K	feS assembly ATPase SufC
FM022_02980	ENOG4107RIU	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins (By similarity)
FM022_02985	ENOG4105CJW	magnesium transporter
FM022_02990	ENOG4105BZU	Histidine kinase
FM022_02995	ENOG4105CH7	arginosuccinase
FM022_03005	ENOG4105CUZ	uba thif-type nad fad binding protein
FM022_03010	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
FM022_03020	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
FM022_03025	ENOG4105C8Q	Methyl-accepting chemotaxis
FM022_03030	ENOG4105CSM	endonuclease III
FM022_03050	ENOG4105C8Q	Methyl-accepting chemotaxis
FM022_03100	ENOG4108YZG	isomerase
FM022_03105	ENOG4105C3F	Signal peptidase i
FM022_03110	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
FM022_03115	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
FM022_03120	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
FM022_03145	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
FM022_03155	ENOG410692R	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
FM022_03160	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
FM022_03170	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
FM022_03175	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
FM022_03180	ENOG4105CRQ	synthase (Component I)
FM022_03190	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
FM022_03195	ENOG4105CRK	lysyL-tRNA synthetase
FM022_03205	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
FM022_03215	ENOG4105CDU	Replicative dna helicase
FM022_03230	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
FM022_03240	ENOG4105D2T	synthase
FM022_03245	ENOG4107SE4	UDP-N-acetylglucosamine 2-epimerase
FM022_03255	ENOG4105F0R	Cytidylyltransferase
FM022_03260	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
FM022_03270	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
FM022_03305	ENOG4108UW5	maltose o-acetyltransferase
FM022_03340	ENOG4105C5E	polysaccharide biosynthesis protein
FM022_03345	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
FM022_03365	ENOG4105ESV	Glycosyl transferase, family 4
FM022_03370	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
FM022_03390	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
FM022_03395	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
FM022_03415	ENOG4105M15	transport protein ExbD
FM022_03420	ENOG4105M8K	biopolymer transport protein
FM022_03435	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
FM022_03440	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
FM022_03485	ENOG41090R7	Ferric uptake
FM022_03495	ENOG4105C9Q	fumarate hydratase class II
FM022_03505	ENOG4105RAK	Histidine kinase
FM022_03510	ENOG41074H6	response regulator
FM022_03515	ENOG4108ESX	Receptor
FM022_03520	ENOG4107E2E	PKHD-type hydroxylase
FM022_03530	ENOG4105D05	Receptor
FM022_03550	ENOG4105D22	carbon starvation protein
FM022_03555	ENOG4105C3G	gtp-binding protein
FM022_03575	ENOG4105NBK	UPF0345 protein
FM022_03585	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
FM022_03590	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
FM022_03605	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
FM022_03610	ENOG4105CPF	Cell wall formation (By similarity)
FM022_03620	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
FM022_03635	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
FM022_03640	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
FM022_03645	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
FM022_03650	ENOG4105KZZ	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
FM022_03655	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FM022_03660	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
FM022_03665	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
FM022_03670	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
FM022_03675	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
FM022_03680	ENOG41084HJ	50s ribosomal protein l29
FM022_03685	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
FM022_03690	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
FM022_03695	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
FM022_03700	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FM022_03705	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
FM022_03710	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
FM022_03715	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
FM022_03720	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
FM022_03725	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
FM022_03730	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
FM022_03735	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
FM022_03740	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
FM022_03745	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
FM022_03750	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
FM022_03760	ENOG4105C9M	aspartyl-trna synthetase
FM022_03775	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
FM022_03780	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
FM022_03805	ENOG4107QW4	alcohol dehydrogenase
FM022_03810	ENOG4105C8Q	Methyl-accepting chemotaxis
FM022_03815	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
FM022_03820	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
FM022_03825	ENOG4105C8Q	Methyl-accepting chemotaxis
FM022_03830	ENOG4105C8Q	Methyl-accepting chemotaxis
FM022_03835	ENOG4105C8Q	Methyl-accepting chemotaxis
FM022_03840	ENOG4105C8Q	Methyl-accepting chemotaxis
FM022_03855	ENOG41062JF	Transcriptional regulator
FM022_03890	ENOG4105BZU	Histidine kinase
FM022_03895	ENOG4105CGK	Exodeoxyribonuclease III
FM022_03915	ENOG4105QNF	Outer membrane lipoprotein
FM022_03940	ENOG4105BZU	Histidine kinase
FM022_03945	ENOG4105DY9	regulatoR
FM022_03950	ENOG4108HRK	Histidine kinase
FM022_03955	ENOG4105EWK	phytoene
FM022_03960	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
FM022_03980	ENOG4107QP8	phosphohexose isomerase
FM022_03985	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
FM022_04020	ENOG4105C8Q	Methyl-accepting chemotaxis
FM022_04025	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
FM022_04030	ENOG4105VSH	4-oxalocrotonate tautomerase
FM022_04040	ENOG4105DK0	Indole-3-glycerol phosphate synthase
FM022_04050	ENOG4105QTX	Pfam:UPF0153
FM022_04065	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
FM022_04070	ENOG4105DQU	oxidoreductase, subunit beta
FM022_04080	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
FM022_04085	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
FM022_04090	ENOG4105DJV	ribulose-phosphate 3-epimerase
FM022_04095	ENOG4105HDD	phospholipase
FM022_04105	ENOG4107VIJ	nudix hydrolase
FM022_04110	ENOG4108VPT	UPF0234 protein
FM022_04125	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
FM022_04140	ENOG4105DFA	alanine racemase domain protein
FM022_04145	ENOG4105DZP	Membrane-associated zinc metalloprotease
FM022_04155	ENOG4105CAN	Short-chain dehydrogenase reductase Sdr
FM022_04160	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
FM022_04170	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
FM022_04175	ENOG4105BZ1	(ABC) transporter
FM022_04180	ENOG4105CJR	Integral membrane protein (MviN
FM022_04195	ENOG41080V7	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
FM022_04205	ENOG4107UIE	peptidase
FM022_04210	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
FM022_04215	ENOG4105IPS	esterase
FM022_04220	ENOG4105CA0	peroxidase
FM022_04235	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
FM022_04240	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FM022_04245	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
FM022_04250	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
FM022_04255	ENOG4106H78	methyltransferase
FM022_04260	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
FM022_04265	ENOG4105E1F	short-chain dehydrogenase reductase
FM022_04285	ENOG4105NQN	cytochrome C
FM022_04295	ENOG4108STX	response regulator
FM022_04300	ENOG4105US7	Histidine kinase
FM022_04305	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
FM022_04315	ENOG4105KTH	gatB Yqey
FM022_04320	ENOG4105C5H	ABC transporter
FM022_04330	ENOG4105C3M	thioredoxin reductase
FM022_04335	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
FM022_04370	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
FM022_04375	ENOG4108IYU	L-aspartate oxidase
FM022_04385	ENOG4108VKG	metal-dependent hydrolase
FM022_04390	ENOG4105CHM	Aminotransferase
FM022_04395	ENOG41076HS	cation diffusion facilitator family transporter
FM022_04400	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
FM022_04440	ENOG4105FCD	Major Facilitator
FM022_04450	ENOG4105G01	cobalamin (vitamin B12) biosynthesis CbiM protein
FM022_04470	ENOG4105D5K	Hemolysin activator protein
FM022_04475	ENOG4105CKT	filamentous hemagglutinin
FM022_04475	ENOG4105CKT	filamentous hemagglutinin
FM022_04530	ENOG4105DSF	transport protein
FM022_04555	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
FM022_04565	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
FM022_04575	ENOG4105D7W	serine acetyltransferase
FM022_04580	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
FM022_04585	ENOG4105CUT	histidyl-tRNA synthetase
FM022_04590	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
FM022_04595	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
FM022_04600	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
FM022_04610	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
FM022_04615	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
FM022_04640	ENOG4105K6T	rare lipoprotein A
FM022_04645	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
FM022_04650	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
FM022_04665	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
FM022_04670	ENOG4105KY5	gCN5-related N-acetyltransferase
FM022_04690	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
FM022_04730	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
FM022_04735	ENOG4105CN7	Flagellar biosynthetic protein FliP
FM022_04740	ENOG4105CJN	penicillin-binding protein
FM022_04760	ENOG4105CAK	Cell division ATP-binding protein ftsE
FM022_04765	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
FM022_04775	ENOG4105C34	Pseudouridine synthase
FM022_04790	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
FM022_04795	ENOG4105NBK	UPF0345 protein
FM022_04815	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
FM022_04820	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
FM022_04825	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
FM022_04840	ENOG41067V7	50S ribosomal protein L36
FM022_04845	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FM022_04850	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
FM022_04855	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
FM022_04860	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
FM022_04865	ENOG4108ZT0	50S ribosomal protein l17
FM022_04870	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
FM022_04875	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
FM022_04925	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
FM022_04945	ENOG4105BZU	Histidine kinase
FM022_04965	ENOG4105DKW	ABC transporter
FM022_05000	ENOG4105KVH	Transcriptional regulator
FM022_05005	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
FM022_05030	ENOG4108V1U	phospholipid-binding protein
FM022_05035	ENOG4105DUM	transcriptional regulator, lysR family
FM022_05070	ENOG4105KVH	Transcriptional regulator
FM022_05075	ENOG4105NF4	modulator of drug activity
FM022_05080	ENOG4105NF4	modulator of drug activity
FM022_05085	ENOG4108DBC	nitroreductase
FM022_05095	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
FM022_05105	ENOG4108RCM	Nitroreductase
FM022_05115	ENOG4105C5H	ABC transporter
FM022_05130	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
FM022_05135	ENOG4106032	Glutathionylspermidine synthase
FM022_05140	ENOG4108UHV	Lipoprotein
FM022_05145	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
FM022_05150	ENOG4105E2X	shikimate dehydrogenase
FM022_05155	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
FM022_05160	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
FM022_05165	ENOG4105C6K	Malic enzyme
FM022_05170	ENOG4105CIY	formyltetrahydrofolate deformylase
FM022_05175	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
FM022_05200	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
FM022_05210	ENOG4107QX8	SPFH domain, Band 7 family protein
FM022_05235	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
FM022_05240	ENOG4105I08	Pseudouridine synthase
FM022_05245	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
FM022_05265	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
FM022_05270	ENOG4105D5T	phosphonate abc transporter
FM022_05275	ENOG4105EHG	Permease protein
FM022_05285	ENOG4105CVJ	phosphoglycerate mutase
FM022_05290	ENOG4105BZ1	(ABC) transporter
FM022_05300	ENOG4108STX	response regulator
FM022_05305	ENOG4105BZU	Histidine kinase
FM022_05330	ENOG4105BZU	Histidine kinase
FM022_05340	ENOG4105C1J	atp-dependent rna helicase
FM022_05345	ENOG4105BZU	Histidine kinase
FM022_05350	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
FM022_05355	ENOG4105CDV	Ompa motb domain protein
FM022_05360	ENOG4108JJA	ABC, transporter
FM022_05385	ENOG4105D49	3-dehydroquinate synthase
FM022_05395	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
FM022_05410	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
FM022_05415	ENOG4107RDF	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
FM022_05465	ENOG4107QY8	reductase
FM022_05480	ENOG4105C98	muts2 protein
FM022_05485	ENOG4105C37	(CBS) domain
FM022_05495	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
FM022_05500	ENOG4105BZU	Histidine kinase
FM022_05505	ENOG4108YZA	Nitrogen regulatory protein pii
FM022_05525	ENOG4105C7K	acetolactate synthase
FM022_05530	ENOG4108ZP8	Acetolactate synthase small subunit
FM022_05535	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
FM022_05540	ENOG4105CNU	cell division protein FtsK
FM022_05555	ENOG4105K5B	UPF0225 protein
FM022_05560	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
FM022_05565	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
FM022_05570	ENOG4105CHH	sulfate transporter
FM022_05580	ENOG4105C12	Phosphoribosylglycinamide synthetase
FM022_05600	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
FM022_05605	ENOG4108VYJ	response regulator receiver protein
FM022_05610	ENOG4105CBS	Chea signal transduction histidine kinase
FM022_05615	ENOG4105BZU	Histidine kinase
FM022_05620	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
FM022_05625	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
FM022_05635	ENOG4105EU0	Major facilitator Superfamily
FM022_05640	ENOG4108EU4	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
FM022_05660	ENOG4105DGW	oligopeptidase A
FM022_05665	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
FM022_05670	ENOG4105CSA	Coproporphyrinogen iii oxidase
FM022_05675	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
FM022_05680	ENOG4105CFH	Aspartokinase
FM022_05705	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FM022_05710	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
FM022_05720	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
FM022_05745	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
FM022_05755	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
FM022_05775	ENOG4107QSA	Oxaloacetate decarboxylase
FM022_05780	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
FM022_05805	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
FM022_05820	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
FM022_05830	ENOG4105D52	delta-aminolevulinic acid dehydratase
FM022_05840	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
FM022_05855	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
FM022_05860	ENOG4105DBV	ornithine carbamoyltransferase
FM022_05865	ENOG4105D4P	Coproporphyrinogen iii oxidase
FM022_05890	ENOG4105C4K	Nad synthetase
FM022_05905	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
FM022_05910	ENOG41084AD	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
FM022_05915	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
FM022_05920	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
FM022_05925	ENOG4108JDX	DNA polymerase iii, epsilon subunit
FM022_05940	ENOG4105E46	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process
FM022_05960	ENOG4105DF6	Fe-S oxidoreductase
FM022_05965	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
FM022_05980	ENOG4105C2M	dna polymerase I
FM022_05990	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
FM022_06000	ENOG4108IUZ	ABC transporter
FM022_06005	ENOG4105K8N	protein family UPF0079, ATPase
FM022_06010	ENOG4107QYG	anthranilate phosphoribosyltransferase
FM022_06025	ENOG4105CDH	Citrulline--aspartate ligase
FM022_06030	ENOG4108IQD	Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Catalyzes an ATP-dependent two-step reaction where it forms a high energy D-alanyl AMP intermediate and transfers the alanyl residues from AMP to Dcp (By similarity)
FM022_06035	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
FM022_06045	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
FM022_06050	ENOG4108Z0R	Transferase
FM022_06055	ENOG4107ZYR	domain protein
FM022_06060	ENOG4105CZN	Potassium uptake protein
FM022_06065	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
FM022_06070	ENOG4105C08	Histidine kinase
FM022_06090	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
FM022_06095	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
FM022_06115	ENOG4105C5X	domain protein
FM022_06125	ENOG4105BZU	Histidine kinase
FM022_06130	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
FM022_06140	ENOG4105CRE	cytochrome C
FM022_06145	ENOG4105CIN	aminoacyl-histidine dipeptidase
FM022_06155	ENOG4105C8Q	Methyl-accepting chemotaxis
FM022_06170	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
FM022_06175	ENOG4105D60	lipoprotein releasing system transmembrane protein
FM022_06190	ENOG4105E9K	Isocitrate dehydrogenase
FM022_06195	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
FM022_06220	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
FM022_06265	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
FM022_06270	ENOG4107VQW	regulatoR
FM022_06280	ENOG4105KPV	Transcriptional regulator
FM022_06285	ENOG4105DSQ	Nitric oxide reductase
FM022_06295	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
FM022_06305	ENOG4107YTP	response regulator receiver protein
FM022_06320	ENOG4105DVC	DnaJ domain protein
FM022_06325	ENOG4105KNI	merR family transcriptional Regulator
FM022_06330	ENOG4105D0S	secretion protein (HlyD
FM022_06335	ENOG4105CJ1	ABC, transporter
FM022_06340	ENOG4107QWP	ABC-2 type transporter
FM022_06345	ENOG4107QWP	ABC-2 type transporter
FM022_06350	ENOG4107TS3	membrane protein, TerC
FM022_06375	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
FM022_06385	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
FM022_06395	ENOG4105DWV	Homoserine O-trans-acetylase
FM022_06400	ENOG4105CNM	Receptor
FM022_06410	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
FM022_06415	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
FM022_06435	ENOG4105K89	arsenate reductase
FM022_06475	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
FM022_06480	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
FM022_06490	ENOG4105C25	Primosomal protein n'
FM022_06520	ENOG4105C45	hydrogenase expression formation protein (HypE)
FM022_06530	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
FM022_06535	ENOG4105CQS	hydrogenase expression formation protein HypD
FM022_06540	ENOG4105WRB	Hydrogenase assembly chaperone hypC hupF
FM022_06545	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
FM022_06565	ENOG4105CBX	hi0933 family
FM022_06570	ENOG4105CKW	Inner membrane protein yedI
FM022_06585	ENOG4105VCH	membrane
FM022_06595	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
FM022_06620	ENOG4108P97	
FM022_06625	ENOG4108USZ	hydrogenase
FM022_06630	ENOG4105X7T	Ni Fe-hydrogenase, b-type cytochrome subunit
FM022_06635	ENOG4105DPX	Hydrogenase, large subunit
FM022_06640	ENOG4105E3S	small subunit
FM022_06655	ENOG4108P97	
FM022_06670	ENOG4105DPX	Hydrogenase, large subunit
FM022_06675	ENOG4105E3S	small subunit
FM022_06690	ENOG4108IG5	Transcriptional regulator
FM022_06695	ENOG4107QIJ	Aconitate hydratase 2
FM022_06710	ENOG4105CDY	transcriptional regulatory protein
FM022_06715	ENOG410903C	(LipO)protein
FM022_06730	ENOG4108URH	decarboxylase
FM022_06735	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
FM022_06800	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
FM022_06805	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
FM022_06825	ENOG4105C8Y	Acetylornithine aminotransferase
FM022_06835	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
FM022_06840	ENOG4105DF9	Lipoate-protein, ligase
FM022_06845	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
FM022_06850	ENOG4107QSN	dihydrolipoamide acetyltransferase
FM022_06860	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
FM022_06880	ENOG4105C1J	atp-dependent rna helicase
FM022_06885	ENOG4105DDY	UPF0142 protein ycaO
FM022_06900	ENOG4105C8Q	Methyl-accepting chemotaxis
FM022_06910	ENOG4105DF3	Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds (By similarity)
FM022_06930	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
FM022_06940	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
FM022_06950	ENOG4105QAX	Iron-sulfur
FM022_06990	ENOG4105K3M	)-transporter
FM022_07005	ENOG4108KS2	transglutaminase domain protein
FM022_07015	ENOG4105QAX	Iron-sulfur
FM022_07020	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
FM022_07030	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
FM022_07090	ENOG4105EM7	Selenocysteine-specific translation elongation factor
FM022_07135	ENOG4105BZU	Histidine kinase
FM022_07150	ENOG4105DCI	Phosphohydrolase
FM022_07160	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
FM022_07165	ENOG4105BZU	Histidine kinase
FM022_07170	ENOG4105C1J	atp-dependent rna helicase
FM022_07190	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
FM022_07215	ENOG4105F1S	paraquat-inducible protein a
FM022_07230	ENOG4105BZU	Histidine kinase
FM022_07250	ENOG4108Z66	YbaK ebsC protein
FM022_07260	ENOG4105F1N	DNA alkylation repair
FM022_07275	ENOG4108MIC	Mg-protoporphyrin IX methyl transferase
FM022_07280	ENOG4105CNM	Receptor
FM022_07300	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
FM022_07310	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
FM022_07315	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
FM022_07320	ENOG4105CUY	Mechanosensitive ion channel
FM022_07325	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
FM022_07340	ENOG4108IJ0	Aspartate ammonia-lyase
FM022_07345	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
FM022_07350	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
FM022_07355	ENOG4108YZY	peptidylprolyl cis-trans isomerase
FM022_07370	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
FM022_07380	ENOG4105M8F	Biopolymer transport protein exbD tolR
FM022_07385	ENOG4105E02	MotA TolQ exbB proton channel
FM022_07390	ENOG41082MC	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
FM022_07395	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
FM022_07400	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
FM022_07405	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
FM022_07410	ENOG4105PQH	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
FM022_07425	ENOG4105FA0	parb-like partition protein
FM022_07430	ENOG4107QJE	Chromosome Partitioning Protein
FM022_07445	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
FM022_07450	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
FM022_07455	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FM022_07460	ENOG4105K46	50S ribosomal protein l27
FM022_07465	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
FM022_07470	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
FM022_07480	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
FM022_07485	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
FM022_07495	ENOG4105D0M	Protease HtpX homolog
FM022_07515	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
FM022_07525	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
FM022_07530	ENOG4108512	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
FM022_07535	ENOG41067YR	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
FM022_07540	ENOG4105VG0	50S ribosomal protein l34
FM022_07545	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
FM022_07550	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
FM022_07560	ENOG4105CSR	polyphosphate kinase 2
FM022_07570	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
FM022_07575	ENOG4105E0X	reductase
FM022_07580	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
FM022_07605	ENOG4105DC1	bifunctional purine biosynthesis protein purh
FM022_07610	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
FM022_07620	ENOG4105DR5	peptidase
FM022_07625	ENOG4105EUJ	GTP cyclohydrolase i
FM022_07630	ENOG4105D7N	magnesium and cobalt transport protein CorA
FM022_07655	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
FM022_07700	ENOG4105C8Q	Methyl-accepting chemotaxis
FM022_07715	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
FM022_07720	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
FM022_07725	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
FM022_07735	ENOG4105CSR	polyphosphate kinase 2
FM022_07765	ENOG4105C28	cystathionine
FM022_07780	ENOG4105C8Q	Methyl-accepting chemotaxis
FM022_07790	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
FM022_07795	ENOG4105C8Q	Methyl-accepting chemotaxis
FM022_07855	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
FM022_07890	ENOG41084IH	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
FM022_07915	ENOG4105DWF	phosphomethylpyrimidine kinase
FM022_07920	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
FM022_07945	ENOG4107VQW	regulatoR
FM022_07960	ENOG4107QPI	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
FM022_07980	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
FM022_07995	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
FM022_08000	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
FM022_08005	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
FM022_08015	ENOG4105F4G	Membrane
FM022_08055	ENOG41082XB	radical SAM domain protein
FM022_08060	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
FM022_08070	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
FM022_08085	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
FM022_08095	ENOG4105VB9	50S ribosomal protein l28
FM022_08105	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
FM022_08110	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
FM022_08115	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
FM022_08160	ENOG4105CPK	Glycosyl transferase (Group 1
FM022_08185	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
FM022_08195	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
FM022_08225	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
FM022_08235	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
FM022_08240	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
FM022_08260	ENOG4105DKP	glycosyl transferase, family 9
FM022_08270	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
FM022_08280	ENOG4105BZ8	glutamate synthase
FM022_08285	ENOG4105CBC	glutamate synthase
FM022_08300	ENOG4105C8Q	Methyl-accepting chemotaxis
FM022_08305	ENOG4105C8Q	Methyl-accepting chemotaxis
FM022_08310	ENOG4105GVR	general secretion pathway protein D
FM022_08315	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
FM022_08320	ENOG4105DX0	Hemolysin A
FM022_08325	ENOG4105DTN	riboflavin biosynthesis protein ribF
FM022_08330	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
FM022_08335	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FM022_08350	ENOG4107S2Z	UPF0761 membrane protein
FM022_08360	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
FM022_08370	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
FM022_08375	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
FM022_08380	ENOG4105M7K	Involved in the transcription termination process (By similarity)
FM022_08385	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
FM022_08450	ENOG4105XFK	Ferrous iron transport protein A
FM022_08455	ENOG4105CE1	Ferrous iron transport protein b
FM022_08480	ENOG4105C59	p-type ATPase
FM022_08490	ENOG4105CNM	Receptor
FM022_08500	ENOG4105BZS	acriflavin resistance protein
FM022_08515	ENOG4105VEQ	Cold shock protein
FM022_08520	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
FM022_08525	ENOG4105BZU	Histidine kinase
FM022_08555	ENOG4105DKK	Benzoate
FM022_08570	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
FM022_08575	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
FM022_08580	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
FM022_08585	ENOG4108VZM	50s ribosomal protein L10
FM022_08590	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
FM022_08595	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
FM022_08600	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
FM022_08615	ENOG41086AR	50S ribosomal protein L33
FM022_08620	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
FM022_08650	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
FM022_08655	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
FM022_08665	ENOG4108JQC	penicillin-binding protein 1A
FM022_08675	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
FM022_08680	ENOG4105C5F	glutamine synthetase
FM022_08690	ENOG4108ZEX	molybdopterin converting factor, subunit 2
FM022_08700	ENOG4108XUR	Pfam:DUF178
FM022_08705	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
FM022_08715	ENOG4105CNI	cell division protein FtsW
FM022_08725	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
FM022_08765	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
FM022_08770	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
FM022_08790	ENOG4105DJG	MaoC domain protein dehydratase
FM022_08810	ENOG4105C8Q	Methyl-accepting chemotaxis
FM022_08815	ENOG4107R5R	arsenical pump membrane protein
FM022_08835	ENOG4108UXE	Protein tyrosine phosphatase
FM022_08840	ENOG4107XC4	flavin reductase domain protein, FMN-binding
FM022_08850	ENOG4105D7B	Flagellar biosynthesis protein flha
FM022_08855	ENOG4105DTJ	flagellar hook-associated protein
FM022_08860	ENOG4108JIR	Flagellum-specific ATP synthase
FM022_08870	ENOG4105D00	flagellar biosynthetic protein flhB
FM022_08885	ENOG4108ZC9	flagellar basal-body rod protein flgc
FM022_08890	ENOG41084DA	flagellar hook-basal body complex protein fliE
FM022_08900	ENOG4107R21	site-determining protein
FM022_08905	ENOG4105FZW	flagellar biosynthesis regulator FlhF
FM022_08920	ENOG4105YKR	
FM022_08925	ENOG4105DD5	Flagellar motor switch protein
FM022_08945	ENOG4105BZE	flagellar hook protein, FlgE
FM022_08960	ENOG4105DD5	Flagellar motor switch protein
FM022_08970	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
FM022_08975	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
FM022_08980	ENOG4105Q75	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
FM022_08985	ENOG4105KTQ	flagellar basal-body rod protein
FM022_09000	ENOG4105CGA	flagellar basal-body rod protein FlgG
FM022_09015	ENOG4105V3S	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
FM022_09025	ENOG4105K5M	30s ribosomal protein S16
FM022_09030	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FM022_09040	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
FM022_09050	ENOG4105EGD	dinuclear metal center protein, YbgI family
FM022_09055	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
FM022_09065	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
FM022_09075	ENOG4105CFP	Peptidase U32
FM022_09080	ENOG41080BE	Methyl-accepting chemotaxis sensory transducer
FM022_09080	ENOG41080BE	Methyl-accepting chemotaxis sensory transducer
FM022_09085	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
FM022_09090	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
FM022_09095	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
FM022_09100	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
FM022_09105	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
FM022_09120	ENOG4105D05	Receptor
FM022_09140	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
FM022_09180	ENOG4105DDQ	anthranilate synthase
FM022_09190	ENOG4107QVT	Binding-protein-dependent transport systems, inner membrane component
FM022_09205	ENOG4105E0K	tonB-dependent siderophore receptor
FM022_09250	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
FM022_09275	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
FM022_09285	ENOG4107T5V	SNARE associated Golgi
FM022_09290	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
FM022_09295	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
FM022_09305	ENOG4107QYE	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
FM022_09310	ENOG4105C7B	Threonine dehydratase
FM022_09315	ENOG4107WJT	it plays a direct role in the translocation of protons across the membrane (By similarity)
FM022_09325	ENOG4105YIC	Major outer membrane protein
FM022_09335	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
FM022_09345	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
FM022_09360	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
FM022_09370	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
FM022_09385	ENOG4105MGB	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
FM022_09390	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
FM022_09400	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
FM022_09410	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
FM022_09415	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
FM022_09420	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
FM022_09425	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
FM022_09430	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
FM022_09440	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
FM022_09445	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
FM022_09450	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
FM022_09455	ENOG4105CHR	reductase
FM022_09460	ENOG4107SPB	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
FM022_09470	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
FM022_09480	ENOG4107YV6	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
FM022_09490	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
FM022_09500	ENOG4107QID	Threonine synthase
FM022_09505	ENOG4105CAS	nag kinase
FM022_09510	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
FM022_09520	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
FM022_09525	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
FM022_09565	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
FM022_09570	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
FM022_09575	ENOG4107Z7S	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
FM022_09580	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
FM022_09585	ENOG4105C4R	Atp-dependent dna helicase
FM022_09590	ENOG4105DUM	transcriptional regulator, lysR family
FM022_09595	ENOG4105N5T	Radical SAM Protein
FM022_09600	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
FM022_09605	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
FM022_09610	ENOG4105C3M	thioredoxin reductase
FM022_09620	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
FM022_09645	ENOG4105BZU	Histidine kinase
FM022_09650	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
FM022_09655	ENOG4105C0H	protease
FM022_09660	ENOG4105C01	Dihydroxy-acid dehydratase
FM022_09690	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
FM022_09710	ENOG4108TX7	
FM022_09725	ENOG4105C8V	SAICAR synthetase
FM022_09730	ENOG4105VR9	phosphoribosylformylglycinamidine synthase
FM022_09735	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
FM022_09745	ENOG4105E9Q	Acyl-transferase
FM022_09750	ENOG4105WMR	Protein CrcB homolog
FM022_09755	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
FM022_09760	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
FM022_09765	ENOG4105C75	arginyL-tRNA synthetase
FM022_09775	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
FM022_09785	ENOG4105BZA	Phosphoglycerate kinase
FM022_09795	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
FM022_09800	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
FM022_09805	ENOG4105CQC	Prephenate dehydratase
FM022_09810	ENOG4105CIH	Imidazole acetol-phosphate transaminase
FM022_09815	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
FM022_09820	ENOG4105CA0	peroxidase
FM022_09855	ENOG4107TT5	NLP P60 protein
FM022_09870	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
FM022_09875	ENOG4105C26	Dehydrogenase
FM022_09880	ENOG4105C7K	acetolactate synthase
FM022_09885	ENOG4108V0P	LemA family
FM022_09900	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
FM022_09930	ENOG4105BZU	Histidine kinase
FM022_09940	ENOG4105BZS	acriflavin resistance protein
FM022_09945	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
FM022_09970	ENOG4105CBX	hi0933 family
FM022_09990	ENOG4105C6T	cysteine synthase
FM022_10005	ENOG4105C11	sulfate adenylyltransferase), subunit 2
FM022_10010	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
FM022_10060	ENOG4108K7V	UPF0284 protein
FM022_10065	ENOG4107QPK	)-transporter
FM022_10075	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
FM022_10080	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
FM022_10095	ENOG4105BZU	Histidine kinase
FM022_10100	ENOG4105DJ4	phosphatidylserine decarboxylase
FM022_10110	ENOG4105CA3	membrane-bound lytic murein transglycosylase
FM022_10115	ENOG4105CFG	Acts as a chaperone (By similarity)
FM022_10120	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FM022_10135	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
FM022_10150	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
FM022_10155	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
FM022_10160	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
FM022_10175	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
FM022_10180	ENOG4105M6F	mutator MutT protein
FM022_10210	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
FM022_10230	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
FM022_10235	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
FM022_10240	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
FM022_10245	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
FM022_10250	ENOG4105WPN	DNA integration recombination invertion protein
FM022_10265	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
FM022_10270	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
FM022_10280	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
FM022_10290	ENOG4105CZQ	inner membrane transport protein YdhC
FM022_10295	ENOG4105CHH	sulfate transporter
FM022_10315	ENOG4105DHM	ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis (By similarity)
FM022_10320	ENOG4105UK2	Sulfatase-modifying factor enzyme 1
FM022_10325	ENOG4105E63	Pfam:DUF178
FM022_10330	ENOG4105D4A	Cell wall formation (By similarity)
FM022_10345	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
FM022_10360	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
FM022_10365	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
FM022_10375	ENOG4105C5E	polysaccharide biosynthesis protein
FM022_10380	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
FM022_10390	ENOG4105D2T	synthase
FM022_10410	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
FM022_10435	ENOG4105I03	Flagellin
FM022_10440	ENOG4105C58	cytochrome c oxidase accessory protein ccog
FM022_10445	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
FM022_10450	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
FM022_10475	ENOG4105C0B	DNA polymerase III (alpha subunit)
FM022_10480	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
FM022_10495	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
FM022_10575	ENOG410802Z	Protein of unknown function (DUF328)
FM022_10605	ENOG4105C8Q	Methyl-accepting chemotaxis
FM022_10630	ENOG4108IJ6	ABC transporter
FM022_10645	ENOG4105C6T	cysteine synthase
FM022_10660	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
FM022_10665	ENOG4108IYI	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
FM022_10670	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
FM022_10685	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
FM022_10690	ENOG4105GVF	(ABC) transporter
FM022_10700	ENOG4105E2Y	ABC, transporter
FM022_10705	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
FM022_10715	ENOG4105GVF	(ABC) transporter
FM022_10745	ENOG4105CI3	gtp-binding protein typa
FM022_10750	ENOG41066VF	YeeE YedE family protein
FM022_10755	ENOG4105KSU	Redox protein
FM022_10790	ENOG4105BZU	Histidine kinase
FM022_10835	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
FM022_10840	ENOG4105F3H	Histidine kinase
FM022_10845	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
FM022_10855	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
FM022_10860	ENOG4107R2U	Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity)
FM022_10880	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)