locus-tag	class	description
ACIB15232_0001	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ACIB15232_0002	COG0592	DNA-directed DNA polymerase activity
ACIB15232_0003	COG0187	DNA topoisomerase II activity
ACIB15232_0004	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ACIB15232_0008	COG0500	methyltransferase
ACIB15232_0013	COG3174	membrane
ACIB15232_0017	COG2895	sulfate adenylyltransferase (ATP) activity
ACIB15232_0018	COG0175	sulfate reduction
ACIB15232_0022	COG1959	2 iron, 2 sulfur cluster binding
ACIB15232_0025	COG2081	HI0933 family
ACIB15232_0028	COG1538	Outer membrane efflux protein
ACIB15232_0029	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ACIB15232_0031	COG3706	GGDEF domain
ACIB15232_0033	COG2814	Major facilitator Superfamily
ACIB15232_0034	COG0783	Belongs to the Dps family
ACIB15232_0035	COG0546	phosphoglycolate phosphatase activity
ACIB15232_0037	COG1012	belongs to the aldehyde dehydrogenase family
ACIB15232_0038	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ACIB15232_0043	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ACIB15232_0044	COG3022	response to hydroperoxide
ACIB15232_0048	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ACIB15232_0049	COG0233	cytoplasmic translational termination
ACIB15232_0051	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ACIB15232_0053	COG0352	thiamine-phosphate diphosphorylase activity
ACIB15232_0054	COG0670	Belongs to the BI1 family
ACIB15232_0064	COG1028	Short-chain dehydrogenase reductase Sdr
ACIB15232_0065	COG1083	cytidylyl-transferase
ACIB15232_0068	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ACIB15232_0069	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ACIB15232_0069	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ACIB15232_0070	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ACIB15232_0071	COG2089	acid synthase
ACIB15232_0073	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ACIB15232_0076	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ACIB15232_0077	COG0148	phosphopyruvate hydratase activity
ACIB15232_0080	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ACIB15232_0083	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ACIB15232_0084	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
ACIB15232_0085	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ACIB15232_0086	COG0315	cyclic pyranopterin monophosphate synthase activity
ACIB15232_0089	COG1007	ATP synthesis coupled electron transport
ACIB15232_0091	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ACIB15232_0092	COG0713	ATP synthesis coupled electron transport
ACIB15232_0093	COG0839	Belongs to the complex I subunit 6 family
ACIB15232_0094	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACIB15232_0095	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ACIB15232_0099	COG0649	NAD binding
ACIB15232_0100	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACIB15232_0101	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACIB15232_0102	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACIB15232_0103	COG1222	aaa ATPase
ACIB15232_0106	COG0659	secondary active sulfate transmembrane transporter activity
ACIB15232_0107	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
ACIB15232_0108	COG1252	NADH dehydrogenase
ACIB15232_0110	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ACIB15232_0111	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ACIB15232_0112	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ACIB15232_0113	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ACIB15232_0114	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ACIB15232_0118	COG0445	tRNA wobble uridine modification
ACIB15232_0119	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ACIB15232_0120	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ACIB15232_0122	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ACIB15232_0123	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ACIB15232_0124	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ACIB15232_0127	COG0101	tRNA pseudouridine synthase activity
ACIB15232_0129	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ACIB15232_0130	COG0443	Heat shock 70 kDa protein
ACIB15232_0132	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
ACIB15232_0134	COG0688	phosphatidylethanolamine metabolic process
ACIB15232_0135	COG3287	FIST C domain
ACIB15232_0135	COG2200	EAL domain
ACIB15232_0135	COG2199	diguanylate cyclase activity
ACIB15232_0138	COG0189	ligase activity
ACIB15232_0139	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ACIB15232_0140	COG3118	belongs to the thioredoxin family
ACIB15232_0141	COG4232	protein-disulfide reductase activity
ACIB15232_0143	COG0471	metal ion transport
ACIB15232_0146	COG1028	Short-chain dehydrogenase reductase Sdr
ACIB15232_0148	COG5002	protein histidine kinase activity
ACIB15232_0149	COG0745	RESPONSE REGULATOR receiver
ACIB15232_0151	COG0129	dihydroxy-acid dehydratase activity
ACIB15232_0163	COG0849	cell division
ACIB15232_0169	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ACIB15232_0171	COG0745	RESPONSE REGULATOR receiver
ACIB15232_0180	COG1136	(ABC) transporter
ACIB15232_0182	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ACIB15232_0183	COG0585	pseudouridine synthase activity
ACIB15232_0186	COG0793	Belongs to the peptidase S41A family
ACIB15232_0188	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ACIB15232_0189	COG0047	phosphoribosylformylglycinamidine synthase activity
ACIB15232_0191	COG0204	Acyl-transferase
ACIB15232_0193	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ACIB15232_0194	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ACIB15232_0195	COG0018	arginyl-trna synthetase
ACIB15232_0197	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ACIB15232_0198	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ACIB15232_0199	COG0126	phosphoglycerate kinase activity
ACIB15232_0200	COG0149	triose-phosphate isomerase activity
ACIB15232_0201	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ACIB15232_0202	COG0019	diaminopimelate decarboxylase activity
ACIB15232_0203	COG1605	Chorismate mutase
ACIB15232_0203	COG0077	Prephenate dehydratase
ACIB15232_0204	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ACIB15232_0205	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ACIB15232_0207	COG0424	maF-like protein
ACIB15232_0209	COG0791	NLP P60 protein
ACIB15232_0210	COG0791	NLP P60 protein
ACIB15232_0214	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ACIB15232_0215	COG3118	belongs to the thioredoxin family
ACIB15232_0216	COG0492	ferredoxin-NADP+ reductase activity
ACIB15232_0217	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ACIB15232_0218	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ACIB15232_0221	COG0210	DNA helicase
ACIB15232_0222	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ACIB15232_0223	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ACIB15232_0224	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ACIB15232_0225	COG3278	Belongs to the heme-copper respiratory oxidase family
ACIB15232_0234	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ACIB15232_0235	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ACIB15232_0236	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ACIB15232_0237	COG1185	polyribonucleotide nucleotidyltransferase activity
ACIB15232_0237	COG0539	negative regulation of cytoplasmic translation
ACIB15232_0238	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ACIB15232_0239	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ACIB15232_0240	COG0072	phenylalanine-tRNA ligase activity
ACIB15232_0240	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ACIB15232_0241	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ACIB15232_0242	COG0537	adenosine 5'-monophosphoramidase activity
ACIB15232_0243	COG0825	malonyl-CoA metabolic process
ACIB15232_0244	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ACIB15232_0245	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ACIB15232_0247	COG0602	queuosine metabolic process
ACIB15232_0249	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ACIB15232_0254	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ACIB15232_0256	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ACIB15232_0257	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ACIB15232_0260	COG0356	it plays a direct role in the translocation of protons across the membrane
ACIB15232_0261	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ACIB15232_0262	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ACIB15232_0264	COG0336	Belongs to the RNA methyltransferase TrmD family
ACIB15232_0265	COG0335	large ribosomal subunit rRNA binding
ACIB15232_0266	COG0586	Pfam SNARE associated Golgi protein
ACIB15232_0267	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ACIB15232_0270	COG0251	oxidation-reduction process
ACIB15232_0272	COG2183	response to ionizing radiation
ACIB15232_0278	COG1178	ABC-type Fe3 transport system permease component
ACIB15232_0279	COG1840	ABC-type Fe3 transport system, periplasmic component
ACIB15232_0280	COG0512	Glutamine amidotransferase of anthranilate synthase
ACIB15232_0288	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ACIB15232_0289	COG0768	penicillin binding
ACIB15232_0290	COG0772	Belongs to the SEDS family
ACIB15232_0291	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ACIB15232_0292	COG1968	undecaprenyl-diphosphatase activity
ACIB15232_0293	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
ACIB15232_0295	COG0314	molybdopterin synthase activity
ACIB15232_0297	COG0174	glutamine synthetase
ACIB15232_0298	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
ACIB15232_0299	COG0444	Belongs to the ABC transporter superfamily
ACIB15232_0300	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ACIB15232_0301	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ACIB15232_0302	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ACIB15232_0307	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ACIB15232_0308	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ACIB15232_0311	COG0250	Participates in transcription elongation, termination and antitermination
ACIB15232_0312	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ACIB15232_0313	COG0081	regulation of translation
ACIB15232_0314	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ACIB15232_0315	COG0222	ribosome binding
ACIB15232_0316	COG0085	RNA polymerase activity
ACIB15232_0317	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ACIB15232_0320	COG0840	transmembrane signaling receptor activity
ACIB15232_0321	COG0450	alkyl hydroperoxide reductase
ACIB15232_0322	COG3118	belongs to the thioredoxin family
ACIB15232_0323	COG1971	Probably functions as a manganese efflux pump
ACIB15232_0328	COG0840	transmembrane signaling receptor activity
ACIB15232_0329	COG2814	Major facilitator Superfamily
ACIB15232_0331	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ACIB15232_0332	COG0049	tRNA binding
ACIB15232_0333	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ACIB15232_0334	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ACIB15232_0335	COG0497	DNA recombination
ACIB15232_0336	COG0840	transmembrane signaling receptor activity
ACIB15232_0336	COG0840	transmembrane signaling receptor activity
ACIB15232_0339	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ACIB15232_0341	COG0752	glycyl-tRNA synthetase alpha subunit
ACIB15232_0342	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ACIB15232_0344	COG1519	Transferase
ACIB15232_0344	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ACIB15232_0345	COG0564	pseudouridine synthase activity
ACIB15232_0346	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ACIB15232_0347	COG0228	four-way junction DNA binding
ACIB15232_0348	COG1837	Belongs to the UPF0109 family
ACIB15232_0349	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ACIB15232_0355	COG4786	Flagellar basal body rod
ACIB15232_0356	COG1815	bacterial-type flagellum-dependent cell motility
ACIB15232_0357	COG1766	The M ring may be actively involved in energy transduction
ACIB15232_0358	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ACIB15232_0360	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ACIB15232_0362	COG1749	Flagellar hook protein flgE
ACIB15232_0363	COG1749	Flagellar hook protein flgE
ACIB15232_0367	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ACIB15232_0371	COG1419	protein localization to endoplasmic reticulum
ACIB15232_0372	COG0455	bacterial-type flagellum organization
ACIB15232_0374	COG1677	Flagellar hook-basal body complex protein FliE
ACIB15232_0378	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ACIB15232_0380	COG1157	protein secretion by the type III secretion system
ACIB15232_0381	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ACIB15232_0382	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ACIB15232_0384	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ACIB15232_0385	COG1970	mechanosensitive ion channel activity
ACIB15232_0390	COG2030	dehydratase
ACIB15232_0393	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ACIB15232_0394	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
ACIB15232_0395	COG0542	response to heat
ACIB15232_0403	COG0277	FAD linked oxidase domain protein
ACIB15232_0405	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ACIB15232_0406	COG2226	methyltransferase
ACIB15232_0409	COG1739	Uncharacterized protein family UPF0029
ACIB15232_0412	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ACIB15232_0414	COG2877	3-deoxy-8-phosphooctulonate synthase activity
ACIB15232_0415	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ACIB15232_0416	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ACIB15232_0417	COG0284	orotidine-5'-phosphate decarboxylase activity
ACIB15232_0430	COG0483	inositol monophosphate 1-phosphatase activity
ACIB15232_0431	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ACIB15232_0433	COG0859	PFAM glycosyl transferase family 9
ACIB15232_0436	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ACIB15232_0444	COG1216	Glycosyl transferase, family 2
ACIB15232_0445	COG1216	Glycosyl transferase, family 2
ACIB15232_0447	COG1696	Membrane protein involved in D-alanine export
ACIB15232_0449	COG1696	Membrane protein involved in D-alanine export
ACIB15232_0451	COG0438	transferase activity, transferring glycosyl groups
ACIB15232_0454	COG0463	Glycosyl transferase, family 2
ACIB15232_0457	COG0859	PFAM glycosyl transferase family 9
ACIB15232_0458	COG1368	sulfuric ester hydrolase activity
ACIB15232_0459	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
ACIB15232_0460	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ACIB15232_0460	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
ACIB15232_0464	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ACIB15232_0466	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ACIB15232_0469	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ACIB15232_0471	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ACIB15232_0479	COG4628	conserved protein (DUF2132)
ACIB15232_0484	COG1570	exodeoxyribonuclease VII activity
ACIB15232_0485	COG0835	chemotaxis
ACIB15232_0488	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
ACIB15232_0489	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ACIB15232_0491	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ACIB15232_0492	COG0459	protein refolding
ACIB15232_0495	COG0745	RESPONSE REGULATOR receiver
ACIB15232_0496	COG5002	protein histidine kinase activity
ACIB15232_0498	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ACIB15232_0499	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ACIB15232_0500	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ACIB15232_0501	COG0352	thiamine-phosphate diphosphorylase activity
ACIB15232_0502	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ACIB15232_0504	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ACIB15232_0505	COG2264	protein methyltransferase activity
ACIB15232_0506	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ACIB15232_0507	COG0628	permease
ACIB15232_0508	COG2255	four-way junction helicase activity
ACIB15232_0509	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ACIB15232_0510	COG0159	tryptophan synthase activity
ACIB15232_0511	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
ACIB15232_0513	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
ACIB15232_0518	COG4753	response regulator
ACIB15232_0518	COG2207	Transcriptional regulator
ACIB15232_0519	COG4191	Histidine kinase
ACIB15232_0523	COG3706	GGDEF domain
ACIB15232_0525	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ACIB15232_0528	COG1846	Transcriptional regulator
ACIB15232_0529	COG1028	Short-chain dehydrogenase reductase Sdr
ACIB15232_0536	COG2326	polyphosphate kinase activity
ACIB15232_0537	COG0544	peptidyl-prolyl cis-trans isomerase activity
ACIB15232_0538	COG0740	serine-type endopeptidase activity
ACIB15232_0539	COG0242	peptide deformylase activity
ACIB15232_0549	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ACIB15232_0563	COG1309	transcriptional regulator
ACIB15232_0566	COG0653	protein targeting
ACIB15232_0568	COG2095	MarC family integral membrane protein
ACIB15232_0569	COG3706	GGDEF domain
ACIB15232_0569	COG0745	RESPONSE REGULATOR receiver
ACIB15232_0570	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ACIB15232_0571	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ACIB15232_0573	COG0481	GTPase activity
ACIB15232_0574	COG2885	chlorophyll binding
ACIB15232_0576	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ACIB15232_0580	COG0482	sulfurtransferase activity
ACIB15232_0581	COG0482	sulfurtransferase activity
ACIB15232_0582	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ACIB15232_0583	COG0006	proline dipeptidase activity
ACIB15232_0584	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ACIB15232_0585	COG0402	S-adenosylhomocysteine deaminase activity
ACIB15232_0586	COG0616	signal peptide processing
ACIB15232_0588	COG0280	phosphate acetyltransferase
ACIB15232_0589	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ACIB15232_0590	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ACIB15232_0591	COG2176	DNA-directed DNA polymerase activity
ACIB15232_0593	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ACIB15232_0599	COG2176	DNA-directed DNA polymerase activity
ACIB15232_0601	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ACIB15232_0603	COG0745	RESPONSE REGULATOR receiver
ACIB15232_0604	COG5002	protein histidine kinase activity
ACIB15232_0613	COG1546	Belongs to the CinA family
ACIB15232_0613	COG1058	Belongs to the CinA family
ACIB15232_0614	COG0579	oxidoreductase
ACIB15232_0615	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ACIB15232_0618	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ACIB15232_0619	COG0052	Belongs to the universal ribosomal protein uS2 family
ACIB15232_0620	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ACIB15232_0621	COG1136	(ABC) transporter
ACIB15232_0623	COG0194	GDP metabolic process
ACIB15232_0625	COG2217	Heavy metal translocating P-type atpase
ACIB15232_0628	COG4608	Belongs to the ABC transporter superfamily
ACIB15232_0629	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ACIB15232_0630	COG1227	inorganic diphosphatase activity
ACIB15232_0631	COG0668	transmembrane transport
ACIB15232_0632	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ACIB15232_0634	COG0010	Belongs to the arginase family
ACIB15232_0635	COG1278	Cold shock
ACIB15232_0636	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ACIB15232_0637	COG0581	inorganic phosphate transmembrane transporter activity
ACIB15232_0638	COG0573	inorganic phosphate transmembrane transporter activity
ACIB15232_0639	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ACIB15232_0646	COG2995	paraquat-inducible protein a
ACIB15232_0647	COG3008	intermembrane lipid transfer
ACIB15232_0653	COG0326	Molecular chaperone. Has ATPase activity
ACIB15232_0654	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACIB15232_0655	COG1129	ABC transporter
ACIB15232_0655	COG0842	Transport permease protein
ACIB15232_0656	COG0842	Transport permease protein
ACIB15232_0658	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ACIB15232_0659	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
ACIB15232_0660	COG0840	transmembrane signaling receptor activity
ACIB15232_0663	COG2200	EAL domain
ACIB15232_0663	COG2199	diguanylate cyclase activity
ACIB15232_0663	COG3287	FIST C domain
ACIB15232_0666	COG0513	Belongs to the DEAD box helicase family
ACIB15232_0668	COG0259	pyridoxamine-phosphate oxidase activity
ACIB15232_0671	COG5002	protein histidine kinase activity
ACIB15232_0672	COG1121	(ABC) transporter
ACIB15232_0673	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ACIB15232_0674	COG2996	Protein conserved in bacteria
ACIB15232_0675	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ACIB15232_0677	COG0673	inositol 2-dehydrogenase activity
ACIB15232_0680	COG0210	DNA helicase
ACIB15232_0681	COG0569	domain protein
ACIB15232_0681	COG0475	glutathione-regulated potassium exporter activity
ACIB15232_0682	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ACIB15232_0698	COG0582	viral genome integration into host DNA
ACIB15232_0708	COG1921	L-seryl-tRNASec selenium transferase activity
ACIB15232_0713	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ACIB15232_0715	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ACIB15232_0717	COG0386	Belongs to the glutathione peroxidase family
ACIB15232_0719	COG1078	dGTPase activity
ACIB15232_0723	COG1305	Transglutaminase-like
ACIB15232_0726	COG4565	transcriptional regulatory protein
ACIB15232_0733	COG0437	4 iron, 4 sulfur cluster binding
ACIB15232_0735	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ACIB15232_0739	COG2998	abc-type tungstate transport system, permease component
ACIB15232_0740	COG4662	Binding-protein-dependent transport system inner membrane component
ACIB15232_0745	COG0446	pyridine nucleotide-disulphide oxidoreductase
ACIB15232_0747	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ACIB15232_0748	COG0306	phosphate transporter
ACIB15232_0751	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ACIB15232_0752	COG0328	RNA-DNA hybrid ribonuclease activity
ACIB15232_0753	COG0840	transmembrane signaling receptor activity
ACIB15232_0756	COG0513	Belongs to the DEAD box helicase family
ACIB15232_0757	COG2217	Heavy metal translocating P-type atpase
ACIB15232_0759	COG1032	radical SAM domain protein
ACIB15232_0760	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ACIB15232_0761	COG0508	dehydrogenase complex catalyzes the overall conversion of
ACIB15232_0762	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ACIB15232_0763	COG0095	Lipoate-protein ligase
ACIB15232_0764	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ACIB15232_0767	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ACIB15232_0768	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ACIB15232_0768	COG0519	Catalyzes the synthesis of GMP from XMP
ACIB15232_0773	COG0596	Alpha beta hydrolase
ACIB15232_0775	COG0116	Belongs to the methyltransferase superfamily
ACIB15232_0775	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ACIB15232_0777	COG2989	Protein conserved in bacteria
ACIB15232_0782	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ACIB15232_0786	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ACIB15232_0786	COG0301	tRNA thio-modification
ACIB15232_0789	COG2814	Major facilitator Superfamily
ACIB15232_0792	COG2354	Protein conserved in bacteria
ACIB15232_0793	COG0726	polysaccharide deacetylase
ACIB15232_0794	COG2081	HI0933 family
ACIB15232_0799	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ACIB15232_0800	COG2171	N-acyltransferase activity
ACIB15232_0802	COG0488	(ABC) transporter
ACIB15232_0803	COG1944	ATP diphosphatase activity
ACIB15232_0805	COG2169	Transcriptional regulator
ACIB15232_0805	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ACIB15232_0806	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ACIB15232_0808	COG0475	glutathione-regulated potassium exporter activity
ACIB15232_0808	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ACIB15232_0810	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
ACIB15232_0814	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ACIB15232_0815	COG1611	Belongs to the LOG family
ACIB15232_0818	COG2853	Lipoprotein
ACIB15232_0819	COG0217	transcriptional regulatory protein
ACIB15232_0825	COG1049	propionate catabolic process, 2-methylcitrate cycle
ACIB15232_0826	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ACIB15232_0828	COG1451	nucleotide metabolic process
ACIB15232_0832	COG2884	Cell division ATP-binding protein ftsE
ACIB15232_0833	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ACIB15232_0835	COG0564	pseudouridine synthase activity
ACIB15232_0836	COG0772	Belongs to the SEDS family
ACIB15232_0837	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
ACIB15232_0838	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ACIB15232_0839	COG3123	guanosine phosphorylase activity
ACIB15232_0842	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ACIB15232_0843	COG0066	3-isopropylmalate dehydratase activity
ACIB15232_0844	COG0473	3-isopropylmalate dehydrogenase activity
ACIB15232_0847	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ACIB15232_0848	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ACIB15232_0849	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ACIB15232_0850	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ACIB15232_0851	COG0202	RNA polymerase activity
ACIB15232_0852	COG0203	ribosomal protein L17
ACIB15232_0853	COG0154	amidase activity
ACIB15232_0854	COG0516	GMP reductase activity
ACIB15232_0854	COG0517	IMP dehydrogenase activity
ACIB15232_0857	COG0840	transmembrane signaling receptor activity
ACIB15232_0858	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ACIB15232_0859	COG0840	transmembrane signaling receptor activity
ACIB15232_0860	COG0754	glutathionylspermidine amidase activity
ACIB15232_0862	COG1119	ATPase activity
ACIB15232_0863	COG2076	Multidrug Resistance protein
ACIB15232_0867	COG2249	NAD(P)H dehydrogenase (quinone) activity
ACIB15232_0868	COG1881	PFAM PEBP family protein
ACIB15232_0871	COG2855	membrane
ACIB15232_0875	COG1733	regulation of RNA biosynthetic process
ACIB15232_0876	COG2249	NAD(P)H dehydrogenase (quinone) activity
ACIB15232_0878	COG0778	Nitroreductase
ACIB15232_0880	COG0488	(ABC) transporter
ACIB15232_0881	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ACIB15232_0884	COG0702	epimerase
ACIB15232_0885	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ACIB15232_0889	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACIB15232_0891	COG0784	Response regulator, receiver
ACIB15232_0891	COG3437	response regulator, receiver
ACIB15232_0892	COG1338	Plays a role in the flagellum-specific transport system
ACIB15232_0893	COG0768	penicillin binding
ACIB15232_0897	COG4191	Histidine kinase
ACIB15232_0898	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ACIB15232_0899	COG0322	excinuclease ABC activity
ACIB15232_0900	COG3201	nicotinamide mononucleotide transporter
ACIB15232_0909	COG1741	Belongs to the pirin family
ACIB15232_0910	COG2205	protein histidine kinase activity
ACIB15232_0911	COG0745	RESPONSE REGULATOR receiver
ACIB15232_0914	COG4895	conserved protein (DUF2196)
ACIB15232_0915	COG3437	response regulator, receiver
ACIB15232_0915	COG0784	Response regulator, receiver
ACIB15232_0918	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ACIB15232_0919	COG0745	RESPONSE REGULATOR receiver
ACIB15232_0920	COG0642	Histidine kinase
ACIB15232_0921	COG3111	PFAM Bacterial OB fold (BOF) protein
ACIB15232_0928	COG0659	secondary active sulfate transmembrane transporter activity
ACIB15232_0933	COG1484	DNA-dependent DNA replication
ACIB15232_0934	COG4584	PFAM Integrase catalytic
ACIB15232_0939	COG4974	Belongs to the 'phage' integrase family
ACIB15232_0940	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ACIB15232_0955	COG0582	viral genome integration into host DNA
ACIB15232_0956	COG0824	Thioesterase
ACIB15232_0958	COG0501	Belongs to the peptidase M48B family
ACIB15232_0959	COG1322	Protein conserved in bacteria
ACIB15232_0960	COG2321	neutral zinc metallopeptidase
ACIB15232_0962	COG0303	'Molybdopterin
ACIB15232_0964	COG0037	tRNA processing
ACIB15232_0966	COG3118	belongs to the thioredoxin family
ACIB15232_0969	COG2203	Gaf domain
ACIB15232_0969	COG3706	GGDEF domain
ACIB15232_0969	COG4251	negative regulation of phosphorylation
ACIB15232_0969	COG5001	Diguanylate cyclase
ACIB15232_0971	COG0248	Ppx GppA phosphatase
ACIB15232_0973	COG0028	Belongs to the TPP enzyme family
ACIB15232_0974	COG0440	acetolactate synthase activity
ACIB15232_0975	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ACIB15232_0976	COG1674	ftsk spoiiie
ACIB15232_0976	COG1196	nuclear chromosome segregation
ACIB15232_0978	COG1114	Component of the transport system for branched-chain amino acids
ACIB15232_0979	COG0861	Integral membrane protein TerC family
ACIB15232_0980	COG0745	RESPONSE REGULATOR receiver
ACIB15232_0981	COG0784	Response regulator, receiver
ACIB15232_0981	COG4191	Histidine kinase
ACIB15232_0982	COG0113	porphobilinogen synthase activity
ACIB15232_0983	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ACIB15232_0984	COG0357	Ribosomal RNA small subunit methyltransferase G
ACIB15232_0987	COG0751	glycine-tRNA ligase activity
ACIB15232_0988	COG0582	viral genome integration into host DNA
ACIB15232_0990	COG1137	ATPase activity
ACIB15232_0992	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ACIB15232_0994	COG0137	argininosuccinate synthase activity
ACIB15232_0995	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ACIB15232_0996	COG1696	Membrane protein involved in D-alanine export
ACIB15232_0998	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ACIB15232_0999	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ACIB15232_1003	COG0310	cobalt ion transport
ACIB15232_1005	COG0375	protein maturation
ACIB15232_1006	COG0309	Hydrogenase expression formation protein (HypE)
ACIB15232_1008	COG2084	Dehydrogenase
ACIB15232_1010	COG0298	carbon dioxide binding
ACIB15232_1011	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
ACIB15232_1018	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
ACIB15232_1019	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
ACIB15232_1021	COG4191	Histidine kinase
ACIB15232_1021	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ACIB15232_1024	COG0484	heat shock protein binding
ACIB15232_1028	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ACIB15232_1029	COG5001	Diguanylate cyclase
ACIB15232_1029	COG3300	MHYT domain
ACIB15232_1030	COG5001	Diguanylate cyclase
ACIB15232_1030	COG4251	negative regulation of phosphorylation
ACIB15232_1030	COG2203	Gaf domain
ACIB15232_1030	COG3706	GGDEF domain
ACIB15232_1034	COG0166	Belongs to the GPI family
ACIB15232_1038	COG0708	Exodeoxyribonuclease III
ACIB15232_1039	COG0500	methyltransferase
ACIB15232_1040	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ACIB15232_1040	COG1333	cytochrome c biogenesis protein
ACIB15232_1041	COG2195	Cleaves the N-terminal amino acid of tripeptides
ACIB15232_1043	COG1193	negative regulation of DNA recombination
ACIB15232_1045	COG0521	Mo-molybdopterin cofactor biosynthetic process
ACIB15232_1047	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ACIB15232_1048	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ACIB15232_1050	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ACIB15232_1053	COG0339	signal peptide processing
ACIB15232_1054	COG2890	protein-(glutamine-N5) methyltransferase activity
ACIB15232_1055	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ACIB15232_1056	COG0494	nUDIX hydrolase
ACIB15232_1057	COG0527	aspartate kinase activity
ACIB15232_1060	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ACIB15232_1061	COG1253	flavin adenine dinucleotide binding
ACIB15232_1063	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ACIB15232_1067	COG2211	Major facilitator Superfamily
ACIB15232_1068	COG0300	oxidoreductase activity
ACIB15232_1069	COG0287	Prephenate dehydrogenase
ACIB15232_1070	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ACIB15232_1071	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
ACIB15232_1072	COG0612	Peptidase, M16
ACIB15232_1073	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ACIB15232_1078	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
ACIB15232_1080	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ACIB15232_1080	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ACIB15232_1083	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
ACIB15232_1084	COG2201	protein-glutamate methylesterase activity
ACIB15232_1085	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
ACIB15232_1086	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ACIB15232_1088	COG0745	RESPONSE REGULATOR receiver
ACIB15232_1089	COG1185	polyribonucleotide nucleotidyltransferase activity
ACIB15232_1093	COG0151	Belongs to the GarS family
ACIB15232_1095	COG1160	GTP binding
ACIB15232_1100	COG0039	L-malate dehydrogenase activity
ACIB15232_1105	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ACIB15232_1105	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
ACIB15232_1106	COG2201	protein-glutamate methylesterase activity
ACIB15232_1108	COG4191	Histidine kinase
ACIB15232_1109	COG0484	heat shock protein binding
ACIB15232_1110	COG0789	Transcriptional regulator
ACIB15232_1114	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ACIB15232_1115	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ACIB15232_1116	COG1663	tetraacyldisaccharide 4'-kinase activity
ACIB15232_1117	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ACIB15232_1121	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ACIB15232_1125	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
ACIB15232_1126	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ACIB15232_1127	COG0805	protein transport
ACIB15232_1128	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ACIB15232_1133	COG0247	lactate metabolic process
ACIB15232_1133	COG2181	nitrate reductase activity
ACIB15232_1134	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ACIB15232_1137	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ACIB15232_1137	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ACIB15232_1138	COG3706	GGDEF domain
ACIB15232_1140	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
ACIB15232_1143	COG0275	rRNA processing
ACIB15232_1145	COG0776	regulation of translation
ACIB15232_1147	COG4974	Belongs to the 'phage' integrase family
ACIB15232_1150	COG3706	GGDEF domain
ACIB15232_1150	COG0745	RESPONSE REGULATOR receiver
ACIB15232_1158	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ACIB15232_1159	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ACIB15232_1160	COG1722	exodeoxyribonuclease VII activity
ACIB15232_1161	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ACIB15232_1163	COG2391	methyltransferase activity
ACIB15232_1164	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ACIB15232_1165	COG0849	cell division
ACIB15232_1169	COG1393	Belongs to the ArsC family
ACIB15232_1173	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
ACIB15232_1174	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
ACIB15232_1175	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ACIB15232_1176	COG3328	transposase activity
ACIB15232_1183	COG0330	HflC and HflK could
ACIB15232_1186	COG0745	RESPONSE REGULATOR receiver
ACIB15232_1189	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ACIB15232_1190	COG0788	formyltetrahydrofolate deformylase activity
ACIB15232_1193	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ACIB15232_1224	COG1917	Cupin 2, conserved barrel domain protein
ACIB15232_1224	COG2207	Transcriptional regulator
ACIB15232_1225	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ACIB15232_1231	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
ACIB15232_1238	COG3706	GGDEF domain
ACIB15232_1240	COG0840	transmembrane signaling receptor activity
ACIB15232_1244	COG0513	Belongs to the DEAD box helicase family
ACIB15232_1245	COG0667	Aldo Keto reductase
ACIB15232_1249	COG2176	DNA-directed DNA polymerase activity
ACIB15232_1250	COG0135	phosphoribosylanthranilate isomerase activity
ACIB15232_1251	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ACIB15232_1255	COG2205	protein histidine kinase activity
ACIB15232_1256	COG0745	RESPONSE REGULATOR receiver
ACIB15232_1257	COG1666	GTP binding
ACIB15232_1258	COG2363	Small membrane protein
ACIB15232_1259	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
ACIB15232_1265	COG0745	RESPONSE REGULATOR receiver
ACIB15232_1266	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ACIB15232_1266	COG4191	Histidine kinase
ACIB15232_1268	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ACIB15232_1271	COG4771	TonB-dependent receptor
ACIB15232_1275	COG0546	phosphoglycolate phosphatase activity
ACIB15232_1277	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
ACIB15232_1278	COG0653	protein targeting
ACIB15232_1283	COG5002	protein histidine kinase activity
ACIB15232_1284	COG0745	RESPONSE REGULATOR receiver
ACIB15232_1286	COG1132	(ABC) transporter
ACIB15232_1288	COG5001	Diguanylate cyclase
ACIB15232_1288	COG3300	MHYT domain
ACIB15232_1290	COG3040	lipid binding
ACIB15232_1291	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ACIB15232_1292	COG3046	protein related to deoxyribodipyrimidine photolyase
ACIB15232_1295	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ACIB15232_1297	COG2200	EAL domain
ACIB15232_1298	COG3279	Response regulator of the LytR AlgR family
ACIB15232_1299	COG3275	phosphorelay sensor kinase activity
ACIB15232_1300	COG1233	COG1233 Phytoene dehydrogenase and related
ACIB15232_1303	COG1090	epimerase
ACIB15232_1304	COG1472	Belongs to the glycosyl hydrolase 3 family
ACIB15232_1305	COG0484	heat shock protein binding
ACIB15232_1306	COG0484	heat shock protein binding
ACIB15232_1308	COG1607	acyl-coa hydrolase
ACIB15232_1310	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ACIB15232_1313	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ACIB15232_1314	COG0131	Imidazoleglycerol-phosphate dehydratase
ACIB15232_1315	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ACIB15232_1316	COG1388	LysM domain
ACIB15232_1316	COG0741	lytic transglycosylase activity
ACIB15232_1317	COG0084	hydrolase, TatD family'
ACIB15232_1320	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
ACIB15232_1321	COG0359	binds to the 23S rRNA
ACIB15232_1323	COG0163	prenyltransferase activity
ACIB15232_1324	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ACIB15232_1325	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ACIB15232_1326	COG0124	histidyl-tRNA synthetase
ACIB15232_1327	COG1166	arginine decarboxylase activity
ACIB15232_1328	COG1045	serine acetyltransferase
ACIB15232_1329	COG0730	response to heat
ACIB15232_1334	COG3706	GGDEF domain
ACIB15232_1335	COG5002	protein histidine kinase activity
ACIB15232_1336	COG0745	RESPONSE REGULATOR receiver
ACIB15232_1338	COG3258	Cytochrome c
ACIB15232_1340	COG0300	oxidoreductase activity
ACIB15232_1341	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ACIB15232_1342	COG0742	ribosomal rna small subunit methyltransferase
ACIB15232_1343	COG1418	mRNA catabolic process
ACIB15232_1344	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ACIB15232_1346	COG0552	protein localization to endoplasmic reticulum
ACIB15232_1349	COG1858	cytochrome C peroxidase
ACIB15232_1354	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ACIB15232_1356	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ACIB15232_1357	COG0735	belongs to the Fur family
ACIB15232_1359	COG0728	peptidoglycan biosynthetic process
ACIB15232_1360	COG1132	(ABC) transporter
ACIB15232_1361	COG0167	dihydroorotate dehydrogenase activity
ACIB15232_1363	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ACIB15232_1364	COG1028	Short-chain dehydrogenase reductase Sdr
ACIB15232_1365	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ACIB15232_1366	COG0750	zinc metalloprotease
ACIB15232_1367	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ACIB15232_1368	COG1942	4-Oxalocrotonate Tautomerase
ACIB15232_1370	COG0134	indole-3-glycerol-phosphate synthase activity
ACIB15232_1372	COG0727	PFAM Uncharacterised protein family (UPF0153)
ACIB15232_1373	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
ACIB15232_1375	COG0674	pyruvate-flavodoxin oxidoreductase activity
ACIB15232_1375	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ACIB15232_1376	COG1013	pyruvate-flavodoxin oxidoreductase activity
ACIB15232_1378	COG1979	alcohol dehydrogenase
ACIB15232_1379	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ACIB15232_1381	COG0563	adenylate kinase activity
ACIB15232_1382	COG0563	adenylate kinase activity
ACIB15232_1384	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ACIB15232_1386	COG1573	uracil-dna glycosylase
ACIB15232_1387	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ACIB15232_1388	COG0024	Methionine aminopeptidase
ACIB15232_1389	COG0201	protein transport
ACIB15232_1390	COG0200	Binds to the 23S rRNA
ACIB15232_1391	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ACIB15232_1392	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ACIB15232_1393	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ACIB15232_1394	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ACIB15232_1395	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ACIB15232_1396	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ACIB15232_1397	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ACIB15232_1398	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ACIB15232_1399	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ACIB15232_1400	COG0255	Belongs to the universal ribosomal protein uL29 family
ACIB15232_1401	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ACIB15232_1402	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ACIB15232_1403	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ACIB15232_1404	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ACIB15232_1405	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ACIB15232_1406	COG0089	rRNA binding
ACIB15232_1407	COG0088	Forms part of the polypeptide exit tunnel
ACIB15232_1408	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ACIB15232_1409	COG0051	transcription antitermination factor activity, RNA binding
ACIB15232_1412	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ACIB15232_1413	COG2267	carboxylic ester hydrolase activity
ACIB15232_1414	COG1181	Belongs to the D-alanine--D-alanine ligase family
ACIB15232_1415	COG0632	four-way junction helicase activity
ACIB15232_1416	COG0840	transmembrane signaling receptor activity
ACIB15232_1419	COG0585	pseudouridine synthase activity
ACIB15232_1420	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ACIB15232_1423	COG3123	guanosine phosphorylase activity
ACIB15232_1427	COG0012	GTP binding
ACIB15232_1429	COG1879	ABC-type sugar transport system periplasmic component
ACIB15232_1430	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ACIB15232_1430	COG4191	Histidine kinase
ACIB15232_1431	COG1966	Carbon starvation protein
ACIB15232_1439	COG3706	GGDEF domain
ACIB15232_1440	COG1136	(ABC) transporter
ACIB15232_1440	COG0577	efflux transmembrane transporter activity
ACIB15232_1441	COG1136	(ABC) transporter
ACIB15232_1441	COG0577	efflux transmembrane transporter activity
ACIB15232_1444	COG0811	peptide transport
ACIB15232_1445	COG0848	biopolymer transport protein
ACIB15232_1447	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ACIB15232_1449	COG0133	tryptophan synthase activity
ACIB15232_1450	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ACIB15232_1452	COG0305	Participates in initiation and elongation during chromosome replication
ACIB15232_1453	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ACIB15232_1454	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ACIB15232_1454	COG4191	Histidine kinase
ACIB15232_1456	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ACIB15232_1457	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ACIB15232_1459	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ACIB15232_1460	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ACIB15232_1461	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ACIB15232_1463	COG0528	UMP kinase activity
ACIB15232_1464	COG1758	RNA polymerase activity
ACIB15232_1466	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ACIB15232_1471	COG0193	aminoacyl-tRNA hydrolase activity
ACIB15232_1472	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ACIB15232_1473	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ACIB15232_1474	COG0681	Belongs to the peptidase S26 family
ACIB15232_1475	COG0698	ribose 5-phosphate isomerase
ACIB15232_1479	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ACIB15232_1480	COG0556	nucleotide-excision repair
ACIB15232_1482	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ACIB15232_1483	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ACIB15232_1485	COG0165	Argininosuccinate lyase
ACIB15232_1486	COG3706	GGDEF domain
ACIB15232_1487	COG2239	Acts as a magnesium transporter
ACIB15232_1488	COG2906	2 iron, 2 sulfur cluster binding
ACIB15232_1488	COG0822	iron-sulfur transferase activity
ACIB15232_1488	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
ACIB15232_1489	COG0719	Fe-S assembly protein
ACIB15232_1490	COG0396	ATPase activity
ACIB15232_1492	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ACIB15232_1493	COG2166	iron-sulfur cluster assembly
ACIB15232_1495	COG0439	Biotin carboxylase
ACIB15232_1497	COG0840	transmembrane signaling receptor activity
ACIB15232_1498	COG0840	transmembrane signaling receptor activity
ACIB15232_1503	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ACIB15232_1504	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ACIB15232_1505	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ACIB15232_1509	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ACIB15232_1510	COG2814	Major facilitator Superfamily
ACIB15232_1513	COG1434	Gram-negative-bacterium-type cell wall biogenesis
ACIB15232_1517	COG0525	valine-tRNA ligase activity
ACIB15232_1520	COG0252	asparaginase activity
ACIB15232_1521	COG1027	Aspartate ammonia-lyase
ACIB15232_1522	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ACIB15232_1523	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ACIB15232_1524	COG1047	Peptidyl-prolyl cis-trans
ACIB15232_1526	COG2885	chlorophyll binding
ACIB15232_1526	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
ACIB15232_1527	COG0823	Involved in the tonB-independent uptake of proteins
ACIB15232_1529	COG0848	biopolymer transport protein
ACIB15232_1530	COG0811	peptide transport
ACIB15232_1531	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ACIB15232_1532	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ACIB15232_1533	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ACIB15232_1534	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ACIB15232_1535	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ACIB15232_1536	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ACIB15232_1538	COG1475	DNA binding
ACIB15232_1539	COG1192	Involved in chromosome partitioning
ACIB15232_1542	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ACIB15232_1543	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ACIB15232_1544	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ACIB15232_1545	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ACIB15232_1546	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ACIB15232_1547	COG0358	DNA primase activity
ACIB15232_1549	COG0571	ribonuclease III activity
ACIB15232_1550	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ACIB15232_1552	COG2194	sulfuric ester hydrolase activity
ACIB15232_1553	COG0501	Belongs to the peptidase M48B family
ACIB15232_1557	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ACIB15232_1559	COG0706	membrane insertase activity
ACIB15232_1560	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ACIB15232_1561	COG0594	ribonuclease P activity
ACIB15232_1562	COG0230	Belongs to the bacterial ribosomal protein bL34 family
ACIB15232_1563	COG0542	response to heat
ACIB15232_1564	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ACIB15232_1565	COG2326	polyphosphate kinase activity
ACIB15232_1568	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ACIB15232_1572	COG4191	Histidine kinase
ACIB15232_1574	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ACIB15232_1576	COG0739	heme binding
ACIB15232_1578	COG0598	Magnesium transport protein CorA
ACIB15232_1582	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ACIB15232_1590	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ACIB15232_1591	COG1858	cytochrome C peroxidase
ACIB15232_1597	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ACIB15232_1599	COG5000	phosphorelay sensor kinase activity
ACIB15232_1603	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ACIB15232_1605	COG1692	metallophosphoesterase
ACIB15232_1607	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ACIB15232_1609	COG0840	transmembrane signaling receptor activity
ACIB15232_1610	COG2081	HI0933 family
ACIB15232_1614	COG4251	negative regulation of phosphorylation
ACIB15232_1614	COG2203	Gaf domain
ACIB15232_1614	COG3706	GGDEF domain
ACIB15232_1614	COG5001	Diguanylate cyclase
ACIB15232_1619	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ACIB15232_1626	COG0285	dihydrofolate synthase activity
ACIB15232_1628	COG0495	leucyl-tRNA aminoacylation
ACIB15232_1630	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ACIB15232_1631	COG1360	Flagellar Motor Protein
ACIB15232_1634	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ACIB15232_1635	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ACIB15232_1636	COG1862	Preprotein translocase
ACIB15232_1637	COG0815	Transfers the fatty acyl group on membrane lipoproteins
ACIB15232_1640	COG0617	tRNA 3'-terminal CCA addition
ACIB15232_1641	COG0668	transmembrane transport
ACIB15232_1642	COG0442	prolyl-tRNA aminoacylation
ACIB15232_1643	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ACIB15232_1644	COG0142	geranyltranstransferase activity
ACIB15232_1646	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ACIB15232_1647	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ACIB15232_1649	COG0811	peptide transport
ACIB15232_1650	COG0848	biopolymer transport protein
ACIB15232_1651	COG0191	fructose-bisphosphate aldolase activity
ACIB15232_1652	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ACIB15232_1653	COG0745	RESPONSE REGULATOR receiver
ACIB15232_1654	COG0642	Histidine kinase
ACIB15232_1655	COG1832	CoA-binding protein
ACIB15232_1656	COG2404	hydrolase activity, acting on ester bonds
ACIB15232_1658	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ACIB15232_1659	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ACIB15232_1660	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ACIB15232_1664	COG0243	molybdopterin cofactor binding
ACIB15232_1665	COG0437	4 iron, 4 sulfur cluster binding
ACIB15232_1666	COG0348	domain, Protein
ACIB15232_1667	COG3043	anaerobic respiration
ACIB15232_1671	COG0840	transmembrane signaling receptor activity
ACIB15232_1672	COG5001	Diguanylate cyclase
ACIB15232_1672	COG5002	protein histidine kinase activity
ACIB15232_1675	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ACIB15232_1676	COG0180	Tryptophanyl-tRNA synthetase
ACIB15232_1677	COG3204	pilus organization
ACIB15232_1679	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ACIB15232_1682	COG3610	response to peptide
ACIB15232_1683	COG3610	response to peptide
ACIB15232_1684	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ACIB15232_1685	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACIB15232_1686	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACIB15232_1687	COG0649	NAD binding
ACIB15232_1687	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACIB15232_1688	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
ACIB15232_1690	COG0372	Belongs to the citrate synthase family
ACIB15232_1691	COG1034	ATP synthesis coupled electron transport
ACIB15232_1692	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ACIB15232_1693	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACIB15232_1694	COG0839	Belongs to the complex I subunit 6 family
ACIB15232_1695	COG0713	ATP synthesis coupled electron transport
ACIB15232_1696	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ACIB15232_1698	COG1007	ATP synthesis coupled electron transport
ACIB15232_1700	COG1053	succinate dehydrogenase
ACIB15232_1701	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ACIB15232_1704	COG2824	Alkylphosphonate utilization operon protein PhnA
ACIB15232_1709	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ACIB15232_1711	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
ACIB15232_1713	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ACIB15232_1714	COG2828	Protein conserved in bacteria
ACIB15232_1715	COG1335	isochorismatase
ACIB15232_1716	COG0181	hydroxymethylbilane synthase activity
ACIB15232_1718	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ACIB15232_1719	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ACIB15232_1720	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ACIB15232_1721	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ACIB15232_1722	COG0450	alkyl hydroperoxide reductase
ACIB15232_1724	COG0105	UTP biosynthetic process
ACIB15232_1726	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ACIB15232_1727	COG0416	fatty acid biosynthetic process
ACIB15232_1728	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ACIB15232_1732	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ACIB15232_1733	COG0540	Belongs to the ATCase OTCase family
ACIB15232_1735	COG4773	Receptor
ACIB15232_1737	COG1706	bacterial-type flagellum-dependent cell motility
ACIB15232_1744	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
ACIB15232_1746	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
ACIB15232_1749	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
ACIB15232_1751	COG0288	reversible hydration of carbon dioxide
ACIB15232_1752	COG0156	8-amino-7-oxononanoate synthase activity
ACIB15232_1757	COG2885	chlorophyll binding
ACIB15232_1761	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
ACIB15232_1762	COG0587	DNA-directed DNA polymerase activity
ACIB15232_1766	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
ACIB15232_1766	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ACIB15232_1767	COG0504	CTP synthase activity
ACIB15232_1768	COG0348	domain, Protein
ACIB15232_1770	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ACIB15232_1772	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ACIB15232_1774	COG0157	Belongs to the NadC ModD family
ACIB15232_1775	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
ACIB15232_1777	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
ACIB15232_1779	COG0083	homoserine kinase activity
ACIB15232_1781	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ACIB15232_1782	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ACIB15232_1783	COG0779	Required for maturation of 30S ribosomal subunits
ACIB15232_1784	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ACIB15232_1784	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ACIB15232_1786	COG2121	Domain of unknown function (DUF374)
ACIB15232_1787	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ACIB15232_1789	COG0195	Participates in both transcription termination and antitermination
ACIB15232_1790	COG0215	cysteine-tRNA ligase activity
ACIB15232_1791	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ACIB15232_1792	COG0629	single-stranded DNA binding
ACIB15232_1793	COG0360	Binds together with S18 to 16S ribosomal RNA
ACIB15232_1796	COG0557	exoribonuclease II activity
ACIB15232_1797	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ACIB15232_1802	COG0343	queuine tRNA-ribosyltransferase activity
ACIB15232_1803	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ACIB15232_1804	COG1393	Belongs to the ArsC family
ACIB15232_1805	COG3248	Nucleoside-binding outer membrane protein
ACIB15232_1806	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
ACIB15232_1808	COG0560	Phosphoserine phosphatase
ACIB15232_1810	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ACIB15232_1813	COG0736	holo-[acyl-carrier-protein] synthase activity
ACIB15232_1814	COG0601	transmembrane transport
ACIB15232_1815	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ACIB15232_1817	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ACIB15232_1819	COG0418	dihydroorotase activity
ACIB15232_1823	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
ACIB15232_1825	COG1301	dicarboxylic acid transport
ACIB15232_1831	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ACIB15232_1832	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ACIB15232_1836	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ACIB15232_1839	COG4191	Histidine kinase
ACIB15232_1841	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACIB15232_1848	COG0840	transmembrane signaling receptor activity
ACIB15232_1852	COG0511	ligase activity, forming carbon-carbon bonds
ACIB15232_1859	COG2022	thiamine diphosphate biosynthetic process
ACIB15232_1861	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ACIB15232_1861	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ACIB15232_1863	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ACIB15232_1866	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ACIB15232_1867	COG0575	Belongs to the CDS family
ACIB15232_1872	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ACIB15232_1874	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ACIB15232_1875	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ACIB15232_1878	COG0446	pyridine nucleotide-disulphide oxidoreductase
ACIB15232_1879	COG0746	molybdenum cofactor guanylyltransferase activity
ACIB15232_1880	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ACIB15232_1881	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ACIB15232_1882	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ACIB15232_1883	COG0268	Binds directly to 16S ribosomal RNA
ACIB15232_1884	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ACIB15232_1885	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ACIB15232_1886	COG4943	cyclic-guanylate-specific phosphodiesterase activity
ACIB15232_1887	COG0573	inorganic phosphate transmembrane transporter activity
ACIB15232_1888	COG0581	inorganic phosphate transmembrane transporter activity
ACIB15232_1889	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ACIB15232_1890	COG0704	Plays a role in the regulation of phosphate uptake
ACIB15232_1892	COG0745	RESPONSE REGULATOR receiver
ACIB15232_1893	COG2205	protein histidine kinase activity
ACIB15232_1894	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ACIB15232_1895	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ACIB15232_1896	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
ACIB15232_1898	COG0351	phosphomethylpyrimidine kinase
ACIB15232_1898	COG0352	thiamine-phosphate diphosphorylase activity
ACIB15232_1900	COG0546	phosphoglycolate phosphatase activity
ACIB15232_1905	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ACIB15232_1906	COG1854	S-ribosylhomocysteine lyase activity
ACIB15232_1908	COG1686	Belongs to the peptidase S11 family
ACIB15232_1910	COG0505	Belongs to the CarA family
ACIB15232_1912	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ACIB15232_1913	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
ACIB15232_1914	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ACIB15232_1917	COG2353	YceI-like domain
ACIB15232_1921	COG0460	homoserine dehydrogenase
ACIB15232_1922	COG0436	Aminotransferase
ACIB15232_1924	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ACIB15232_1925	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ACIB15232_1926	COG0254	rRNA binding
ACIB15232_1927	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ACIB15232_1934	COG4974	Belongs to the 'phage' integrase family
ACIB15232_1935	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ACIB15232_1936	COG1086	Polysaccharide biosynthesis protein
ACIB15232_1938	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ACIB15232_1943	COG1086	Polysaccharide biosynthesis protein
ACIB15232_1956	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ACIB15232_1987	COG3550	peptidyl-serine autophosphorylation
ACIB15232_1989	COG2801	Transposase and inactivated derivatives
ACIB15232_1990	COG2963	transposase activity
ACIB15232_1993	COG0556	nucleotide-excision repair
ACIB15232_1998	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ACIB15232_2023	COG0237	dephospho-CoA kinase activity
ACIB15232_2024	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ACIB15232_2027	COG1410	methionine synthase
ACIB15232_2027	COG0646	methionine synthase
ACIB15232_2029	COG0803	Belongs to the bacterial solute-binding protein 9 family
ACIB15232_2031	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ACIB15232_2036	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ACIB15232_2036	COG0140	phosphoribosyl-ATP diphosphatase activity
ACIB15232_2038	COG0489	protein tyrosine kinase activity
ACIB15232_2041	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ACIB15232_2041	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ACIB15232_2042	COG0745	RESPONSE REGULATOR receiver
ACIB15232_2043	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ACIB15232_2044	COG2353	YceI-like domain
ACIB15232_2045	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ACIB15232_2049	COG0745	RESPONSE REGULATOR receiver
ACIB15232_2049	COG3706	GGDEF domain
ACIB15232_2050	COG5002	protein histidine kinase activity
ACIB15232_2050	COG3850	Histidine kinase
ACIB15232_2052	COG0724	RNA recognition motif
ACIB15232_2053	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ACIB15232_2054	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ACIB15232_2057	COG0107	imidazoleglycerol-phosphate synthase activity
ACIB15232_2058	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ACIB15232_2060	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ACIB15232_2060	COG0517	IMP dehydrogenase activity
ACIB15232_2061	COG1187	pseudouridine synthase activity
ACIB15232_2062	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
ACIB15232_2062	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ACIB15232_2064	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ACIB15232_2066	COG0367	asparagine synthase
ACIB15232_2068	COG0306	phosphate transporter
ACIB15232_2069	COG0513	Belongs to the DEAD box helicase family
ACIB15232_2070	COG0439	Biotin carboxylase
ACIB15232_2071	COG0511	ligase activity, forming carbon-carbon bonds
ACIB15232_2072	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ACIB15232_2072	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ACIB15232_2074	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ACIB15232_2075	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ACIB15232_2076	COG0604	alcohol dehydrogenase
ACIB15232_2079	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ACIB15232_2080	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ACIB15232_2081	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ACIB15232_2082	COG0564	pseudouridine synthase activity
ACIB15232_2084	COG2860	membrane
ACIB15232_2085	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
ACIB15232_2086	COG3706	GGDEF domain
ACIB15232_2087	COG2770	Histidine kinase
ACIB15232_2087	COG2205	protein histidine kinase activity
ACIB15232_2088	COG0745	RESPONSE REGULATOR receiver
ACIB15232_2096	COG0425	Belongs to the sulfur carrier protein TusA family
ACIB15232_2100	COG1959	2 iron, 2 sulfur cluster binding
ACIB15232_2101	COG2199	diguanylate cyclase activity
ACIB15232_2101	COG3287	FIST C domain
ACIB15232_2101	COG2200	EAL domain
ACIB15232_2102	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
ACIB15232_2103	COG4208	sulfate ABC transporter
ACIB15232_2104	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ACIB15232_2106	COG1408	metallophosphoesterase
ACIB15232_2107	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ACIB15232_2109	COG0133	tryptophan synthase activity
ACIB15232_2111	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ACIB15232_a0004	COG0305	Participates in initiation and elongation during chromosome replication
ACIB15232_a0006	COG1475	DNA binding
ACIB15232_a0007	COG1192	Involved in chromosome partitioning
ACIB15232_a0008	COG0514	ATP-dependent DNA helicase (RecQ)
ACIB15232_a0019	COG0071	Belongs to the small heat shock protein (HSP20) family
ACIB15232_a0020	COG0745	RESPONSE REGULATOR receiver
ACIB15232_a0030	COG3152	Membrane
ACIB15232_a0043	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ACIB15232_a0044	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ACIB15232_a0045	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACIB15232_a0046	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ACIB15232_a0047	COG1116	anion transmembrane transporter activity
ACIB15232_a0050	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ACIB15232_a0052	COG4215	(ABC) transporter
ACIB15232_a0053	COG1126	abc transporter atp-binding protein
ACIB15232_a0054	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
ACIB15232_a0055	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ACIB15232_a0061	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ACIB15232_a0062	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ACIB15232_a0063	COG1045	serine acetyltransferase
ACIB15232_a0066	COG0840	transmembrane signaling receptor activity
ACIB15232_a0067	COG0840	transmembrane signaling receptor activity
ACIB15232_a0070	COG0840	transmembrane signaling receptor activity
ACIB15232_a0073	COG1742	UPF0060 membrane protein
ACIB15232_a0076	COG0428	transporter
ACIB15232_a0077	COG4771	TonB-dependent receptor
ACIB15232_a0082	COG0582	viral genome integration into host DNA
ACIB15232_a0083	COG4895	conserved protein (DUF2196)
ACIB15232_a0085	COG4191	Histidine kinase
ACIB15232_a0088	COG2337	Toxic component of a toxin-antitoxin (TA) module
ACIB15232_a0090	COG1278	Cold shock
ACIB15232_a0110	COG4895	conserved protein (DUF2196)
ACIB15232_a0111	COG1222	aaa ATPase
ACIB15232_a0130	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ACIB15232_a0137	COG0776	regulation of translation
ACIB15232_a0167	COG0210	DNA helicase
ACIB15232_a0172	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ACIB15232_a0197	COG2207	Transcriptional regulator
ACIB15232_a0197	COG1917	Cupin 2, conserved barrel domain protein
ACIB15232_a0202	COG3111	PFAM Bacterial OB fold (BOF) protein
ACIB15232_a0205	COG0745	RESPONSE REGULATOR receiver
ACIB15232_a0212	COG2356	endonuclease I
ACIB15232_a0216	COG3118	belongs to the thioredoxin family
ACIB15232_a0217	COG0450	alkyl hydroperoxide reductase
ACIB15232_a0218	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
ACIB15232_a0219	COG0840	transmembrane signaling receptor activity
ACIB15232_a0220	COG0840	transmembrane signaling receptor activity
ACIB15232_a0222	COG4628	conserved protein (DUF2132)