locus-tag	class	description
ACLO_0001	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
ACLO_0002	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
ACLO_0003	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
ACLO_0004	ENOG4105CAY	ferredoxin--nadp reductase
ACLO_0005	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
ACLO_0008	ENOG4105W39	Membrane
ACLO_0009	ENOG4105CBP	Major Facilitator
ACLO_0010	ENOG4105EI2	Pseudouridine synthase
ACLO_0011	ENOG4107QTF	adenylosuccinate lyase
ACLO_0012	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
ACLO_0013	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
ACLO_0015	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
ACLO_0019	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
ACLO_0021	ENOG4105BZ8	glutamate synthase
ACLO_0023	ENOG4105CE9	30S ribosomal protein S2
ACLO_0026	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
ACLO_0027	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
ACLO_0028	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
ACLO_0031	ENOG4105BZU	Histidine kinase
ACLO_0032	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
ACLO_0033	ENOG4107QR9	Iron-sulfur cluster binding protein
ACLO_0034	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
ACLO_0036	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
ACLO_0037	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
ACLO_0038	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
ACLO_0039	ENOG4105C1J	atp-dependent rna helicase
ACLO_0040	ENOG4105CJ3	phosphate transporter
ACLO_0042	ENOG4105CAQ	asparagine synthetase
ACLO_0044	ENOG4105E7Q	Cob(II)yrinic acid a,c-diamide reductase
ACLO_0048	ENOG4108IAB	Phoh family
ACLO_0049	ENOG4108YXA	Membrane
ACLO_0050	ENOG4105D1H	recombination factor protein RarA
ACLO_0051	ENOG4105FE9	pseudouridine synthase
ACLO_0052	ENOG4105C2X	Arabinose 5-phosphate isomerase
ACLO_0054	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
ACLO_0055	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
ACLO_0058	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
ACLO_0059	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
ACLO_0060	ENOG4105VFU	Rna-binding protein
ACLO_0063	ENOG4105BZU	Histidine kinase
ACLO_0067	ENOG4108IJF	Heavy metal efflux pump, CzcA
ACLO_0068	ENOG4108YYC	ycei family
ACLO_0071	ENOG4105D6E	homoserine dehydrogenase
ACLO_0072	ENOG4105CHM	Aminotransferase
ACLO_0076	ENOG41082DI	50s ribosomal protein l31
ACLO_0077	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
ACLO_0103	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
ACLO_0104	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
ACLO_0105	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
ACLO_0106	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
ACLO_0107	ENOG41084QV	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
ACLO_0108	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
ACLO_0109	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
ACLO_0110	ENOG4105C2I	pirin domain protein
ACLO_0111	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
ACLO_0113	ENOG41090MY	MarR family Transcriptional regulator
ACLO_0114	ENOG4107UUH	Aminotransferase
ACLO_0115	ENOG4105CYE	ATP phosphoribosyltransferase regulatory subunit
ACLO_0116	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
ACLO_0118	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
ACLO_0121	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
ACLO_0124	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
ACLO_0125	ENOG4105D1F	ATP-binding protein
ACLO_0127	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
ACLO_0129	ENOG4105CM2	brancheD-chain amino acid aminotransferase
ACLO_0131	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
ACLO_0132	ENOG4105C8Q	Methyl-accepting chemotaxis
ACLO_0135	ENOG4105D3R	alkyl hydroperoxide reductase
ACLO_0138	ENOG4108I6A	alcohol dehydrogenase
ACLO_0139	ENOG4105BZU	Histidine kinase
ACLO_0141	ENOG4105DZ1	carboxypeptidase
ACLO_0144	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
ACLO_0148	ENOG4105F3T	(LipO)protein
ACLO_0149	ENOG4105CY3	ABC transporter, permease
ACLO_0150	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
ACLO_0153	ENOG4108KK1	membrane protein AbrB duplication
ACLO_0154	ENOG4105KVH	Transcriptional regulator
ACLO_0155	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
ACLO_0156	ENOG4105DDK	oxidoreductase, beta subunit
ACLO_0157	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
ACLO_0159	ENOG4105EJ5	oxidoreductase gamma subunit
ACLO_0160	ENOG4107XGZ	Hydrolase
ACLO_0162	ENOG4108UJD	30S ribosomal protein S9
ACLO_0163	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
ACLO_0165	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
ACLO_0167	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
ACLO_0168	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
ACLO_0169	ENOG4105E2Z	phosphate ABC transporter (Permease
ACLO_0170	ENOG4105C8U	phosphate abc transporter
ACLO_0171	ENOG4105PWN	phosphate abc transporter
ACLO_0173	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
ACLO_0174	ENOG4108317	Binds directly to 16S ribosomal RNA (By similarity)
ACLO_0175	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
ACLO_0176	ENOG410813J	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
ACLO_0177	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
ACLO_0179	ENOG4107SA8	fad-dependent pyridine nucleotide-disulfide oxidoreductase
ACLO_0182	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
ACLO_0183	ENOG41084M8	50s ribosomal protein L35
ACLO_0184	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
ACLO_0190	ENOG4105KNE	Phosphatidate cytidylyltransferase
ACLO_0191	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
ACLO_0195	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
ACLO_0196	ENOG4108ZJT	translation initiation factor, Sui1
ACLO_0197	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
ACLO_0198	ENOG4105VF7	tolerance protein
ACLO_0199	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
ACLO_0207	ENOG4105D85	methylase
ACLO_0210	ENOG4107R3N	Filamentation induced by cAMP protein fic
ACLO_0211	ENOG4105F6A	helicase
ACLO_0212	ENOG4105ECI	YeeC-like protein
ACLO_0216	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
ACLO_0218	ENOG4105MZU	cell filamentation protein
ACLO_0219	ENOG4108YZM	Toxic component of a toxin-antitoxin (TA) module (By similarity)
ACLO_0220	ENOG4108C33	Resolvase
ACLO_0222	ENOG4105KK4	UPF0060 membrane protein
ACLO_0223	ENOG4105C59	p-type ATPase
ACLO_0230	ENOG4105EKQ	RNA-directed DNA polymerase
ACLO_0232	ENOG4108IFH	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ACLO_0243	ENOG4105C59	p-type ATPase
ACLO_0247	ENOG4105E3B	Multicopper oxidase
ACLO_0252	ENOG4108JU5	Magnesium and cobalt efflux protein
ACLO_0253	ENOG4105DSF	transport protein
ACLO_0254	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
ACLO_0258	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
ACLO_0285	ENOG4108KU3	Integrase
ACLO_0289	ENOG4105D9Q	decarboxylase (Beta subunit)
ACLO_0290	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
ACLO_0294	ENOG4105C8Q	Methyl-accepting chemotaxis
ACLO_0298	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
ACLO_0300	ENOG4108JJA	ABC, transporter
ACLO_0301	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
ACLO_0303	ENOG4105BZU	Histidine kinase
ACLO_0304	ENOG4105CV1	Transketolase (EC 2.2.1.1)
ACLO_0308	ENOG41067MG	lrgb family
ACLO_0310	ENOG4105KK4	UPF0060 membrane protein
ACLO_0313	ENOG4105CHH	sulfate transporter
ACLO_0314	ENOG4105BZU	Histidine kinase
ACLO_0315	ENOG4105BZU	Histidine kinase
ACLO_0319	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
ACLO_0321	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
ACLO_0325	ENOG4108YZA	Nitrogen regulatory protein pii
ACLO_0327	ENOG4108YZA	Nitrogen regulatory protein pii
ACLO_0328	ENOG4105EKE	dihydroorotase
ACLO_0329	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
ACLO_0330	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
ACLO_0332	ENOG4105VS8	Flagellar biosynthetic protein fliq
ACLO_0337	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
ACLO_0338	ENOG4105E1Q	flagellar hook-associated protein
ACLO_0339	ENOG4107W9T	flagellar hook-associated
ACLO_0343	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
ACLO_0344	ENOG4107R03	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
ACLO_0346	ENOG410829W	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
ACLO_0348	ENOG4105EAC	phosphoserine phosphatase
ACLO_0349	ENOG4107V25	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
ACLO_0350	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
ACLO_0351	ENOG4105DRB	nucleoside-specific channel-forming protein
ACLO_0352	ENOG4105KUZ	arsenate reductase
ACLO_0353	ENOG410855J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
ACLO_0354	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
ACLO_0356	ENOG4105CHM	Aminotransferase
ACLO_0358	ENOG4105DFU	Cell wall formation (By similarity)
ACLO_0360	ENOG4105PXI	polysaccharide deacetylase
ACLO_0361	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
ACLO_0362	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
ACLO_0364	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
ACLO_0365	ENOG4108UUM	single-stranded DNA-binding protein
ACLO_0366	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
ACLO_0368	ENOG4105C8N	cysteinyl-tRNA synthetase
ACLO_0369	ENOG4105CHV	Transcription elongation factor NusA
ACLO_0371	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
ACLO_0372	ENOG4105KB8	(LipO)protein
ACLO_0374	ENOG4105DVY	radical SAM domain protein
ACLO_0377	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
ACLO_0378	ENOG41082UM	UPF0102 protein
ACLO_0381	ENOG4105CDV	Ompa motb domain protein
ACLO_0382	ENOG4105CA9	Pyruvate kinase
ACLO_0385	ENOG4105C8Y	Acetylornithine aminotransferase
ACLO_0387	ENOG4105CXT	aspartate transcarbamylase
ACLO_0392	ENOG4108UMN	azlc family
ACLO_0393	ENOG4105KMT	branched-chain amino acid
ACLO_0394	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
ACLO_0395	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
ACLO_0396	ENOG4105YQ2	50s ribosomal protein l32
ACLO_0398	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
ACLO_0400	ENOG4105D3R	alkyl hydroperoxide reductase
ACLO_0401	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
ACLO_0402	ENOG4105D82	Glutamate dehydrogenase
ACLO_0403	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
ACLO_0404	ENOG4107QMP	dna polymerase iii subunits gamma and tau
ACLO_0406	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
ACLO_0408	ENOG4108K0B	C-di-gmp phosphodiesterase
ACLO_0409	ENOG4105C7F	AcnD-accessory protein PrpF
ACLO_0410	ENOG4108I0Z	Aconitate hydratase
ACLO_0411	ENOG4105BZN	citrate synthase
ACLO_0412	ENOG4105CR4	methylisocitrate lyase
ACLO_0414	ENOG4105C5I	Dehydrogenase
ACLO_0419	ENOG4105C9U	ATP-dependent DNA helicase RecQ
ACLO_0420	ENOG4108BSC	Methyltransferase
ACLO_0423	ENOG4108VKG	metal-dependent hydrolase
ACLO_0426	ENOG4105E33	succinate dehydrogenase
ACLO_0427	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
ACLO_0428	ENOG4108S24	Fumarate reduCtase
ACLO_0429	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
ACLO_0430	ENOG4105C8S	subunit m
ACLO_0431	ENOG4105D65	subunit l
ACLO_0432	ENOG41080EA	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
ACLO_0435	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
ACLO_0436	ENOG4108IEH	NADH dehydrogenase subunit g
ACLO_0437	ENOG4105BZN	citrate synthase
ACLO_0440	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
ACLO_0441	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
ACLO_0442	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
ACLO_0443	ENOG4105C87	Aminotransferase class I and II
ACLO_0444	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
ACLO_0445	ENOG4107XM3	UPF0442 protein
ACLO_0446	ENOG4105DWK	Membrane
ACLO_0448	ENOG4108VHG	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
ACLO_0449	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
ACLO_0452	ENOG4105BZU	Histidine kinase
ACLO_0456	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
ACLO_0459	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
ACLO_0463	ENOG4108ZMS	Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity)
ACLO_0464	ENOG4105GXZ	Ferredoxin-type protein NapH
ACLO_0465	ENOG4108BGM	Quinol dehydrogenase periplasmic component
ACLO_0466	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
ACLO_0467	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
ACLO_0468	ENOG4108RA0	tripartite ATP-independent periplasmic transporter, DctQ component
ACLO_0469	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
ACLO_0471	ENOG410812K	response regulator receiver protein
ACLO_0472	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
ACLO_0473	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
ACLO_0476	ENOG4107QYG	anthranilate phosphoribosyltransferase
ACLO_0477	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
ACLO_0480	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
ACLO_0481	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
ACLO_0482	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
ACLO_0483	ENOG410847I	Transcriptional regulator, BadM Rrf2 family
ACLO_0484	ENOG4108KA0	Inherit from COG: Phosphoesterase, DHHA1
ACLO_0486	ENOG4105DHQ	Histidine kinase
ACLO_0487	ENOG4105ETX	regulatoR
ACLO_0489	ENOG4105D2N	Aldolase
ACLO_0490	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
ACLO_0492	ENOG4105D38	putrescine abc transporter
ACLO_0493	ENOG4107RUE	extracellular solute-binding protein family 1
ACLO_0494	ENOG4105VEQ	Cold shock protein
ACLO_0495	ENOG4105SG9	biopolymer transport protein, ExbD
ACLO_0496	ENOG4105M8K	biopolymer transport protein
ACLO_0498	ENOG4105BZU	Histidine kinase
ACLO_0499	ENOG4105BZU	Histidine kinase
ACLO_0500	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
ACLO_0501	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
ACLO_0503	ENOG4105EAH	synthase
ACLO_0504	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
ACLO_0505	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
ACLO_0507	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
ACLO_0511	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
ACLO_0512	ENOG4105VIE	preprotein translocase, subunit YajC
ACLO_0513	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
ACLO_0514	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
ACLO_0516	ENOG4105C8T	Leucyl-tRNA synthetase
ACLO_0518	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
ACLO_0533	ENOG4108JA2	transcriptioN-repair coupling factor
ACLO_0539	ENOG4105CBX	hi0933 family
ACLO_0540	ENOG4105C8Q	Methyl-accepting chemotaxis
ACLO_0542	ENOG410903D	sensor protein
ACLO_0543	ENOG4108HWS	Histidine kinase
ACLO_0544	ENOG4105D48	metallophosphoesterase
ACLO_0547	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
ACLO_0548	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
ACLO_0549	ENOG4108V3W	Chemotaxis protein, CheW
ACLO_0551	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
ACLO_0553	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
ACLO_0554	ENOG41084FT	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
ACLO_0556	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
ACLO_0557	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
ACLO_0558	ENOG4105ECY	inositol monophosphatase
ACLO_0559	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
ACLO_0562	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
ACLO_0563	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
ACLO_0564	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
ACLO_0565	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
ACLO_0567	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
ACLO_0568	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
ACLO_0569	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
ACLO_0570	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
ACLO_0573	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
ACLO_0576	ENOG4105KJM	monovalent cation h antiporter subunit g
ACLO_0580	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
ACLO_0581	ENOG4108JPZ	Monovalent cation H antiporter subunit D
ACLO_0582	ENOG4108JPZ	Monovalent cation H antiporter subunit D
ACLO_0583	ENOG4105BZU	Histidine kinase
ACLO_0584	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
ACLO_0585	ENOG4105ECP	epimerase
ACLO_0586	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
ACLO_0598	ENOG4105CVR	type I restriction-modification system
ACLO_0599	ENOG41082EK	Restriction modification system DNA (Specificity
ACLO_0603	ENOG4105DZR	Type I site-specific deoxyribonuclease
ACLO_0610	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
ACLO_0611	ENOG4105CDV	Ompa motb domain protein
ACLO_0612	ENOG4105CDV	Ompa motb domain protein
ACLO_0613	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
ACLO_0616	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
ACLO_0617	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
ACLO_0618	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ACLO_0619	ENOG4105DC7	peptidase M24
ACLO_0620	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
ACLO_0621	ENOG4107SYB	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
ACLO_0624	ENOG4108IJ2	phosphate acetyltransferase
ACLO_0625	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
ACLO_0627	ENOG4107S1V	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
ACLO_0629	ENOG4107QN1	sodium solute
ACLO_0631	ENOG4107QN1	sodium solute
ACLO_0633	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
ACLO_0635	ENOG4107QN1	sodium solute
ACLO_0637	ENOG4108STX	response regulator
ACLO_0638	ENOG4105BZU	Histidine kinase
ACLO_0647	ENOG4105CEV	competence damage-inducible protein
ACLO_0648	ENOG4107RSR	Malate quinone oxidoreductase
ACLO_0649	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
ACLO_0653	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
ACLO_0658	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
ACLO_0659	ENOG4105CE9	30S ribosomal protein S2
ACLO_0660	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
ACLO_0663	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
ACLO_0664	ENOG4105BZU	Histidine kinase
ACLO_0665	ENOG4105C59	p-type ATPase
ACLO_0668	ENOG4107H6U	ABC transporter
ACLO_0669	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
ACLO_0670	ENOG4105NBF	ammecr1 domain protein
ACLO_0671	ENOG41074MP	UPF0103 Mediator of ErbB2-driven cell motility-containing protein
ACLO_0672	ENOG4107S90	membrAne
ACLO_0673	ENOG4105FDK	ABC transporter
ACLO_0678	ENOG4105QNR	S1 RNA binding domain protein
ACLO_0679	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
ACLO_0682	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
ACLO_0683	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
ACLO_0684	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
ACLO_0687	ENOG4105ENA	helicase
ACLO_0689	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
ACLO_0694	ENOG41088H4	Diheme cytochrome SoxA (Sulfur oxidation)
ACLO_0697	ENOG4105C7Z	Conserved Protein
ACLO_0707	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
ACLO_0709	ENOG4108UYN	gCN5-related N-acetyltransferase
ACLO_0712	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
ACLO_0713	ENOG4105BZS	acriflavin resistance protein
ACLO_0717	ENOG4106TD9	Diguanylate cyclase
ACLO_0719	ENOG4107RDB	Major Facilitator
ACLO_0720	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
ACLO_0725	ENOG410901F	(LipO)protein
ACLO_0726	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
ACLO_0736	ENOG4105CNG	UPF0061 protein
ACLO_0740	ENOG4105BZS	acriflavin resistance protein
ACLO_0742	ENOG4105KPY	Small multidrug resistance protein
ACLO_0744	ENOG4105BZU	Histidine kinase
ACLO_0746	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
ACLO_0747	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
ACLO_0748	ENOG4105C8Q	Methyl-accepting chemotaxis
ACLO_0754	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
ACLO_0755	ENOG4105C9B	Cysteine desulfurase
ACLO_0757	ENOG4105C3K	feS assembly ATPase SufC
ACLO_0760	ENOG4107RIU	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins (By similarity)
ACLO_0762	ENOG4105CJW	magnesium transporter
ACLO_0767	ENOG4105FQT	
ACLO_0768	ENOG4105CH7	arginosuccinase
ACLO_0770	ENOG4105CUZ	uba thif-type nad fad binding protein
ACLO_0771	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
ACLO_0772	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
ACLO_0775	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
ACLO_0783	ENOG4108YZG	isomerase
ACLO_0784	ENOG4105C3F	Signal peptidase i
ACLO_0785	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
ACLO_0786	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
ACLO_0787	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
ACLO_0792	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
ACLO_0794	ENOG410692R	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
ACLO_0795	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
ACLO_0797	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
ACLO_0798	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
ACLO_0799	ENOG4105CRQ	synthase (Component I)
ACLO_0801	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
ACLO_0802	ENOG4105CRK	lysyL-tRNA synthetase
ACLO_0805	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
ACLO_0807	ENOG4105CDU	Replicative dna helicase
ACLO_0808	ENOG4108VAU	general secretion pathway protein G
ACLO_0810	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
ACLO_0811	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
ACLO_0813	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
ACLO_0815	ENOG4105M15	transport protein ExbD
ACLO_0816	ENOG4105M8K	biopolymer transport protein
ACLO_0819	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
ACLO_0820	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
ACLO_0824	ENOG4107S8A	protein TIM barrel
ACLO_0838	ENOG41090R7	Ferric uptake
ACLO_0841	ENOG4105CE1	Ferrous iron transport protein b
ACLO_0842	ENOG4105XFK	Ferrous iron transport protein A
ACLO_0846	ENOG4107F3C	Hemin uptake protein
ACLO_0847	ENOG4108IU3	tonb-dependent siderophore receptor
ACLO_0848	ENOG4107E2E	PKHD-type hydroxylase
ACLO_0850	ENOG4105D05	Receptor
ACLO_0853	ENOG4105BZU	Histidine kinase
ACLO_0855	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
ACLO_0856	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
ACLO_0859	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
ACLO_0860	ENOG4105CPF	Cell wall formation (By similarity)
ACLO_0861	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
ACLO_0862	ENOG4105DFU	Cell wall formation (By similarity)
ACLO_0865	ENOG4107QMZ	Dehydrogenase
ACLO_0866	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
ACLO_0867	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
ACLO_0868	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
ACLO_0869	ENOG4105KZZ	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
ACLO_0870	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ACLO_0871	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
ACLO_0872	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
ACLO_0873	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
ACLO_0874	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
ACLO_0875	ENOG41084HJ	50s ribosomal protein l29
ACLO_0876	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
ACLO_0877	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
ACLO_0878	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
ACLO_0879	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ACLO_0880	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
ACLO_0881	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
ACLO_0882	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
ACLO_0883	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
ACLO_0884	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
ACLO_0885	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
ACLO_0886	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
ACLO_0887	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
ACLO_0888	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
ACLO_0890	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
ACLO_0892	ENOG4105C9M	aspartyl-trna synthetase
ACLO_0895	ENOG4105CCT	upf0313 protein
ACLO_0896	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
ACLO_0897	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
ACLO_0900	ENOG4105C32	Amino acid ABC transporter (Permease)
ACLO_0902	ENOG4105C0Z	ABC transporter
ACLO_0903	ENOG4108IV0	ABC, transporter
ACLO_0907	ENOG4108YZ9	Urea amidohydrolase subunit gamma
ACLO_0908	ENOG4105CQM	Urea amidohydrolase subunit alpha
ACLO_0911	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
ACLO_0913	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
ACLO_0916	ENOG4105BZU	Histidine kinase
ACLO_0917	ENOG4105CGK	Exodeoxyribonuclease III
ACLO_0923	ENOG4107QP8	phosphohexose isomerase
ACLO_0924	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
ACLO_0925	ENOG4107QKV	phosphomannomutase
ACLO_0932	ENOG4105NBK	UPF0345 protein
ACLO_0936	ENOG4105C3G	gtp-binding protein
ACLO_0937	ENOG4105C7N	Xanthine uracil vitamin C permease
ACLO_0938	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
ACLO_0941	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
ACLO_0942	ENOG4105C2W	permease
ACLO_0943	ENOG4108VPT	UPF0234 protein
ACLO_0947	ENOG4107VIJ	nudix hydrolase
ACLO_0949	ENOG4105HDD	phospholipase
ACLO_0950	ENOG4105DJV	ribulose-phosphate 3-epimerase
ACLO_0951	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
ACLO_0952	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
ACLO_0953	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
ACLO_0955	ENOG4105DQU	oxidoreductase, subunit beta
ACLO_0956	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
ACLO_0958	ENOG41060K3	Methyltransferase
ACLO_0959	ENOG4105QTX	Pfam:UPF0153
ACLO_0961	ENOG4105DK0	Indole-3-glycerol phosphate synthase
ACLO_0963	ENOG4105VSH	4-oxalocrotonate tautomerase
ACLO_0965	ENOG4105DFA	alanine racemase domain protein
ACLO_0966	ENOG4105DZP	Membrane-associated zinc metalloprotease
ACLO_0967	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
ACLO_0968	ENOG4105CAN	Short-chain dehydrogenase reductase Sdr
ACLO_0969	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
ACLO_0972	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
ACLO_0973	ENOG4105BZ1	(ABC) transporter
ACLO_0974	ENOG4105CJR	Integral membrane protein (MviN
ACLO_0976	ENOG4108RAC	Rubrerythrin
ACLO_0978	ENOG4105FEU	K -dependent Na -Ca exchanger
ACLO_0979	ENOG41080V7	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
ACLO_0980	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
ACLO_0988	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
ACLO_0989	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ACLO_0991	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
ACLO_0992	ENOG4106H78	methyltransferase
ACLO_0993	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
ACLO_0995	ENOG4105E1F	short-chain dehydrogenase reductase
ACLO_0998	ENOG4105NQN	cytochrome C
ACLO_1003	ENOG4108PQF	modD protein
ACLO_1005	ENOG4105KTH	gatB Yqey
ACLO_1006	ENOG4105C5H	ABC transporter
ACLO_1008	ENOG4105DUN	Mediates zinc uptake. May also transport other divalent cations (By similarity)
ACLO_1009	ENOG4105DHT	Metal Dependent Phosphohydrolase
ACLO_1010	ENOG41076HS	cation diffusion facilitator family transporter
ACLO_1011	ENOG4105CHM	Aminotransferase
ACLO_1012	ENOG4108VKG	metal-dependent hydrolase
ACLO_1014	ENOG4108IYU	L-aspartate oxidase
ACLO_1015	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
ACLO_1018	ENOG4106A2Z	transcriptional regulator antitoxin, MazE
ACLO_1021	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
ACLO_1029	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
ACLO_1030	ENOG4105PW4	Sugar fermentation stimulation protein homolog
ACLO_1033	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
ACLO_1034	ENOG4105EI2	Pseudouridine synthase
ACLO_1035	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
ACLO_1036	ENOG4105DR4	Methyltransferase
ACLO_1041	ENOG4105E1F	short-chain dehydrogenase reductase
ACLO_1042	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
ACLO_1053	ENOG4108JU5	Magnesium and cobalt efflux protein
ACLO_1054	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
ACLO_1055	ENOG4105DSF	transport protein
ACLO_1056	ENOG4105DHT	Metal Dependent Phosphohydrolase
ACLO_1059	ENOG4108JU6	CBS domain protein
ACLO_1062	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
ACLO_1063	ENOG4108RZE	Tetr family transcriptional regulator
ACLO_1066	ENOG4105C1J	atp-dependent rna helicase
ACLO_1068	ENOG4105D7W	serine acetyltransferase
ACLO_1069	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
ACLO_1070	ENOG4105CUT	histidyl-tRNA synthetase
ACLO_1071	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
ACLO_1072	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
ACLO_1073	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
ACLO_1075	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
ACLO_1076	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
ACLO_1077	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
ACLO_1079	ENOG4105F8V	Hydrolase, tatD family
ACLO_1081	ENOG4105K6T	rare lipoprotein A
ACLO_1082	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
ACLO_1083	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
ACLO_1086	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
ACLO_1088	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
ACLO_1089	ENOG41090Y0	FMN-binding protein
ACLO_1091	ENOG4105BZS	acriflavin resistance protein
ACLO_1093	ENOG410624X	efflux transporter, rnd family, mfp subunit
ACLO_1095	ENOG4105KHC	sulfurtransferase
ACLO_1097	ENOG4105CN7	Flagellar biosynthetic protein FliP
ACLO_1098	ENOG4107RVG	penicillin-binding protein
ACLO_1108	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
ACLO_1109	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
ACLO_1112	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
ACLO_1114	ENOG4105DWV	Homoserine O-trans-acetylase
ACLO_1116	ENOG4105C98	muts2 protein
ACLO_1120	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
ACLO_1125	ENOG4105DKW	ABC transporter
ACLO_1128	ENOG4105CQC	Prephenate dehydratase
ACLO_1129	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
ACLO_1133	ENOG4108V1U	phospholipid-binding protein
ACLO_1134	ENOG4105DUM	transcriptional regulator, lysR family
ACLO_1135	ENOG4105HMI	Membrane
ACLO_1137	ENOG4105C8Q	Methyl-accepting chemotaxis
ACLO_1140	ENOG4105KVH	Transcriptional regulator
ACLO_1141	ENOG4105NF4	modulator of drug activity
ACLO_1143	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
ACLO_1144	ENOG4108RCM	Nitroreductase
ACLO_1146	ENOG4105BZU	Histidine kinase
ACLO_1152	ENOG4105CBS	Chea signal transduction histidine kinase
ACLO_1155	ENOG4108QDE	fad dependent oxidoreductase
ACLO_1158	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
ACLO_1160	ENOG4105QNF	Outer membrane lipoprotein
ACLO_1163	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
ACLO_1166	ENOG4105BZU	Histidine kinase
ACLO_1168	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
ACLO_1171	ENOG4105QNF	Outer membrane lipoprotein
ACLO_1172	ENOG4105CT4	transporter
ACLO_1173	ENOG4107FW0	short-chain dehydrogenase reductase
ACLO_1175	ENOG4105C5H	ABC transporter
ACLO_1176	ENOG4108S4H	thioesterase Superfamily protein
ACLO_1177	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
ACLO_1178	ENOG4105C8Q	Methyl-accepting chemotaxis
ACLO_1179	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
ACLO_1180	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
ACLO_1202	ENOG4105K8R	UPF0145 protein
ACLO_1212	ENOG4105CNU	cell division protein FtsK
ACLO_1213	ENOG4105CIN	aminoacyl-histidine dipeptidase
ACLO_1215	ENOG4105ETX	regulatoR
ACLO_1216	ENOG4105CRE	cytochrome C
ACLO_1222	ENOG4105VTR	Integrase
ACLO_1223	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
ACLO_1226	ENOG4105C5X	domain protein
ACLO_1230	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
ACLO_1231	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
ACLO_1232	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
ACLO_1236	ENOG4108Z0R	Transferase
ACLO_1237	ENOG4105CDH	Citrulline--aspartate ligase
ACLO_1239	ENOG4105D05	Receptor
ACLO_1241	ENOG4107QYG	anthranilate phosphoribosyltransferase
ACLO_1242	ENOG4105K8N	protein family UPF0079, ATPase
ACLO_1243	ENOG4108IUZ	ABC transporter
ACLO_1244	ENOG4105BZU	Histidine kinase
ACLO_1245	ENOG4105BZU	Histidine kinase
ACLO_1246	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
ACLO_1247	ENOG4105C2M	dna polymerase I
ACLO_1251	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
ACLO_1252	ENOG4105DF6	Fe-S oxidoreductase
ACLO_1254	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
ACLO_1260	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
ACLO_1261	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
ACLO_1263	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
ACLO_1267	ENOG4105C4K	Nad synthetase
ACLO_1269	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
ACLO_1271	ENOG4105D4P	Coproporphyrinogen iii oxidase
ACLO_1272	ENOG4105DBV	ornithine carbamoyltransferase
ACLO_1273	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
ACLO_1276	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
ACLO_1277	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
ACLO_1278	ENOG4105D52	delta-aminolevulinic acid dehydratase
ACLO_1279	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
ACLO_1280	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
ACLO_1286	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
ACLO_1288	ENOG4107QX8	SPFH domain, Band 7 family protein
ACLO_1296	ENOG4105M8K	biopolymer transport protein
ACLO_1297	ENOG4105M15	transport protein ExbD
ACLO_1300	ENOG4105EYH	Exonuclease
ACLO_1309	ENOG4105JSC	dimethylmenaquinone methyltransferase
ACLO_1310	ENOG4105EBA	Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity)
ACLO_1311	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
ACLO_1312	ENOG4105I08	Pseudouridine synthase
ACLO_1319	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
ACLO_1320	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
ACLO_1321	ENOG4108JJB	ABC transporter
ACLO_1322	ENOG4105EHG	Permease protein
ACLO_1327	ENOG4105CPC	Aldo Keto reductase
ACLO_1328	ENOG4105E2X	shikimate dehydrogenase
ACLO_1329	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
ACLO_1331	ENOG4105C6K	Malic enzyme
ACLO_1332	ENOG4105CIY	formyltetrahydrofolate deformylase
ACLO_1333	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
ACLO_1339	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
ACLO_1340	ENOG4105D9Q	decarboxylase (Beta subunit)
ACLO_1341	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
ACLO_1345	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
ACLO_1347	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
ACLO_1353	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
ACLO_1355	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
ACLO_1356	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ACLO_1358	ENOG4105EEI	dihydropteroate synthase
ACLO_1361	ENOG4105CFH	Aspartokinase
ACLO_1362	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
ACLO_1363	ENOG4105CSA	Coproporphyrinogen iii oxidase
ACLO_1364	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
ACLO_1365	ENOG4105DGW	oligopeptidase A
ACLO_1369	ENOG4105F4R	Transcriptional regulator mode
ACLO_1370	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
ACLO_1372	ENOG4105E0C	molybdate abc transporter
ACLO_1374	ENOG4108EU4	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
ACLO_1375	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
ACLO_1376	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
ACLO_1377	ENOG4105BZU	Histidine kinase
ACLO_1378	ENOG4105CBS	Chea signal transduction histidine kinase
ACLO_1379	ENOG4108VYJ	response regulator receiver protein
ACLO_1380	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
ACLO_1382	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
ACLO_1386	ENOG4105CHH	sulfate transporter
ACLO_1387	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
ACLO_1389	ENOG4105CNU	cell division protein FtsK
ACLO_1390	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
ACLO_1391	ENOG4108ZP8	Acetolactate synthase small subunit
ACLO_1392	ENOG4105C7K	acetolactate synthase
ACLO_1393	ENOG4105BZU	Histidine kinase
ACLO_1403	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
ACLO_1405	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
ACLO_1408	ENOG4105CGY	Dna recombination protein
ACLO_1409	ENOG4105C2Y	STE24 endopeptidase EC 3.4.24.84
ACLO_1411	ENOG4107YD3	Thioesterase
ACLO_1413	ENOG4105BZU	Histidine kinase
ACLO_1414	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
ACLO_1415	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
ACLO_1416	ENOG4105C8Q	Methyl-accepting chemotaxis
ACLO_1419	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
ACLO_1420	ENOG4105BZU	Histidine kinase
ACLO_1421	ENOG4105C8Q	Methyl-accepting chemotaxis
ACLO_1424	ENOG4105FGV	Chromate
ACLO_1425	ENOG4108UXE	Protein tyrosine phosphatase
ACLO_1428	ENOG41085FC	arsR family transcriptional regulator
ACLO_1429	ENOG4108UHV	Lipoprotein
ACLO_1430	ENOG4106032	Glutathionylspermidine synthase
ACLO_1431	ENOG4105BZU	Histidine kinase
ACLO_1432	ENOG4105EMA	Periplasmic binding protein LacI transcriptional regulator
ACLO_1436	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
ACLO_1437	ENOG4105D60	lipoprotein releasing system transmembrane protein
ACLO_1440	ENOG4105E9K	Isocitrate dehydrogenase
ACLO_1441	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
ACLO_1444	ENOG4105DJI	Methylaspartate mutase, E subunit
ACLO_1446	ENOG4105CEY	Amp-dependent synthetase and ligase
ACLO_1452	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
ACLO_1456	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
ACLO_1458	ENOG410841J	DNA-binding protein Hu
ACLO_1461	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
ACLO_1463	ENOG4107YTP	response regulator receiver protein
ACLO_1466	ENOG4105DVC	DnaJ domain protein
ACLO_1467	ENOG4105KNI	merR family transcriptional Regulator
ACLO_1468	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
ACLO_1483	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
ACLO_1484	ENOG410829K	Lysine exporter protein (Lyse ygga)
ACLO_1485	ENOG4105D06	uba thif-type nad fad binding protein
ACLO_1486	ENOG4108M8H	domain protein
ACLO_1488	ENOG4105C8P	)-transporter
ACLO_1489	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
ACLO_1491	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
ACLO_1492	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
ACLO_1494	ENOG4105D49	3-dehydroquinate synthase
ACLO_1496	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
ACLO_1502	ENOG4105DY9	regulatoR
ACLO_1504	ENOG4105M0J	Toxic component of a toxin-antitoxin (TA) module. A
ACLO_1507	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
ACLO_1511	ENOG4105I03	Flagellin
ACLO_1511	ENOG4105I03	Flagellin
ACLO_1515	ENOG4108STX	response regulator
ACLO_1519	ENOG4105BZ1	(ABC) transporter
ACLO_1520	ENOG4105DSF	transport protein
ACLO_1522	ENOG4105BZU	Histidine kinase
ACLO_1523	ENOG4105K63	Thioredoxin
ACLO_1524	ENOG4105D3R	alkyl hydroperoxide reductase
ACLO_1525	ENOG4105BZU	Histidine kinase
ACLO_1527	ENOG4105D17	glycoside hydrolase, family 3 domain protein
ACLO_1532	ENOG4105DAA	L-lactate
ACLO_1533	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
ACLO_1539	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
ACLO_1540	ENOG4105BZU	Histidine kinase
ACLO_1542	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
ACLO_1543	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
ACLO_1544	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
ACLO_1545	ENOG4108ZT0	50S ribosomal protein l17
ACLO_1546	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
ACLO_1547	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
ACLO_1548	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
ACLO_1549	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ACLO_1550	ENOG41067V7	50S ribosomal protein L36
ACLO_1553	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
ACLO_1554	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
ACLO_1555	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
ACLO_1559	ENOG4105NBK	UPF0345 protein
ACLO_1560	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
ACLO_1565	ENOG4105CNI	cell division protein FtsW
ACLO_1566	ENOG4105C34	Pseudouridine synthase
ACLO_1567	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
ACLO_1568	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
ACLO_1569	ENOG4105CAK	Cell division ATP-binding protein ftsE
ACLO_1572	ENOG4108UPT	UPF0178 protein
ACLO_1574	ENOG4105C5H	ABC transporter
ACLO_1577	ENOG4105C0D	helicase
ACLO_1580	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
ACLO_1581	ENOG4105C25	Primosomal protein n'
ACLO_1587	ENOG4105C45	hydrogenase expression formation protein (HypE)
ACLO_1591	ENOG4105CQS	hydrogenase expression formation protein HypD
ACLO_1592	ENOG4105WRB	Hydrogenase assembly chaperone hypC hupF
ACLO_1593	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
ACLO_1597	ENOG4107XQ1	cobalamin (vitamin B12) biosynthesis CbiM protein
ACLO_1599	ENOG4105C8Q	Methyl-accepting chemotaxis
ACLO_1601	ENOG4105CBX	hi0933 family
ACLO_1604	ENOG4105VCH	membrane
ACLO_1606	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
ACLO_1614	ENOG41080XP	Cbs domain
ACLO_1622	ENOG4105DPX	Hydrogenase, large subunit
ACLO_1623	ENOG4105E3S	small subunit
ACLO_1627	ENOG4107QIJ	Aconitate hydratase 2
ACLO_1632	ENOG4108IQE	Amp-dependent synthetase and ligase
ACLO_1633	ENOG4105CHU	acetyl-coa acetyltransferase
ACLO_1635	ENOG4107QPN	acyl-Coa dehydrogenase
ACLO_1645	ENOG4105BZU	Histidine kinase
ACLO_1649	ENOG4105CDY	transcriptional regulatory protein
ACLO_1650	ENOG4105DR5	peptidase
ACLO_1651	ENOG410903C	(LipO)protein
ACLO_1654	ENOG4108URH	decarboxylase
ACLO_1655	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
ACLO_1664	ENOG4105C94	Transporter
ACLO_1665	ENOG4108ISG	Major Facilitator
ACLO_1669	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
ACLO_1670	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
ACLO_1672	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
ACLO_1676	ENOG4105C1J	atp-dependent rna helicase
ACLO_1677	ENOG4105DDY	UPF0142 protein ycaO
ACLO_1681	ENOG4105C8Q	Methyl-accepting chemotaxis
ACLO_1682	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
ACLO_1683	ENOG4105DF3	Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds (By similarity)
ACLO_1686	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
ACLO_1688	ENOG4107S7U	Sulfide dehydrogenase
ACLO_1692	ENOG4107A5B	Binding-protein-dependent transport systems, inner membrane component
ACLO_1693	ENOG4105C8W	ABC transporter
ACLO_1694	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
ACLO_1696	ENOG4105F4R	Transcriptional regulator mode
ACLO_1698	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
ACLO_1700	ENOG4105QAX	Iron-sulfur
ACLO_1707	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
ACLO_1708	ENOG4105K3M	)-transporter
ACLO_1715	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
ACLO_1723	ENOG4108KS2	transglutaminase domain protein
ACLO_1726	ENOG4105C1Y	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis (By similarity)
ACLO_1727	ENOG4105EM7	Selenocysteine-specific translation elongation factor
ACLO_1732	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
ACLO_1733	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
ACLO_1734	ENOG4105BZU	Histidine kinase
ACLO_1735	ENOG4105BZU	Histidine kinase
ACLO_1736	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
ACLO_1737	ENOG4105BZU	Histidine kinase
ACLO_1744	ENOG4105BZU	Histidine kinase
ACLO_1748	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
ACLO_1749	ENOG4105EKE	dihydroorotase
ACLO_1750	ENOG4108N6H	6-pyruvoyl tetrahydrobiopterin synthase
ACLO_1752	ENOG4105DCI	Phosphohydrolase
ACLO_1753	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
ACLO_1754	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
ACLO_1755	ENOG4105BZU	Histidine kinase
ACLO_1756	ENOG4105C1J	atp-dependent rna helicase
ACLO_1759	ENOG4105BZU	Histidine kinase
ACLO_1763	ENOG4105E7W	lamb ycsf family protein
ACLO_1767	ENOG4105CMI	transporter
ACLO_1768	ENOG4105CJ1	ABC, transporter
ACLO_1769	ENOG4105D0S	secretion protein (HlyD
ACLO_1771	ENOG4105CJ3	phosphate transporter
ACLO_1774	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
ACLO_1775	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
ACLO_1776	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
ACLO_1778	ENOG4105BZU	Histidine kinase
ACLO_1779	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
ACLO_1782	ENOG4105F1S	paraquat-inducible protein a
ACLO_1785	ENOG4105BZU	Histidine kinase
ACLO_1787	ENOG4105C08	Histidine kinase
ACLO_1788	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
ACLO_1789	ENOG4105CZN	Potassium uptake protein
ACLO_1793	ENOG4105C7I	Dehydrogenase
ACLO_1794	ENOG4108Z66	YbaK ebsC protein
ACLO_1795	ENOG4105F1N	DNA alkylation repair
ACLO_1798	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
ACLO_1800	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
ACLO_1801	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
ACLO_1803	ENOG4108IJ0	Aspartate ammonia-lyase
ACLO_1804	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
ACLO_1805	ENOG4105CQZ	Histidine kinase
ACLO_1807	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
ACLO_1808	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
ACLO_1809	ENOG4108YZY	peptidylprolyl cis-trans isomerase
ACLO_1812	ENOG4108UQY	Iron-storage protein
ACLO_1813	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
ACLO_1815	ENOG4105M8F	Biopolymer transport protein exbD tolR
ACLO_1816	ENOG4105E02	MotA TolQ exbB proton channel
ACLO_1817	ENOG41082MC	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
ACLO_1818	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
ACLO_1819	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
ACLO_1820	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
ACLO_1821	ENOG4105PQH	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
ACLO_1822	ENOG4105YF2	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
ACLO_1824	ENOG4105FA0	parb-like partition protein
ACLO_1825	ENOG4107QJE	Chromosome Partitioning Protein
ACLO_1826	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
ACLO_1828	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
ACLO_1829	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
ACLO_1830	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ACLO_1831	ENOG4105K46	50S ribosomal protein l27
ACLO_1832	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
ACLO_1834	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
ACLO_1836	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
ACLO_1837	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
ACLO_1839	ENOG4105D0M	Protease HtpX homolog
ACLO_1842	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
ACLO_1844	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
ACLO_1845	ENOG4108512	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
ACLO_1846	ENOG41067YR	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
ACLO_1847	ENOG4105VG0	50S ribosomal protein l34
ACLO_1848	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
ACLO_1851	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
ACLO_1854	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
ACLO_1855	ENOG4105E0X	reductase
ACLO_1856	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
ACLO_1861	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
ACLO_1863	ENOG4105C72	UPF0176 protein
ACLO_1864	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
ACLO_1866	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
ACLO_1867	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
ACLO_1868	ENOG4107TS3	membrane protein, TerC
ACLO_1870	ENOG4105C8Q	Methyl-accepting chemotaxis
ACLO_1871	ENOG4105C8Q	Methyl-accepting chemotaxis
ACLO_1872	ENOG4105C8Q	Methyl-accepting chemotaxis
ACLO_1873	ENOG4108V06	Glutathione peroxidase
ACLO_1874	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
ACLO_1875	ENOG4108KN0	Choline kinase
ACLO_1876	ENOG4105BZU	Histidine kinase
ACLO_1877	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
ACLO_1878	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
ACLO_1883	ENOG4105DC1	bifunctional purine biosynthesis protein purh
ACLO_1884	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
ACLO_1886	ENOG4105DR5	peptidase
ACLO_1889	ENOG4108JPW	Aminotransferase
ACLO_1890	ENOG4108Z6K	Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant (By similarity)
ACLO_1892	ENOG4105CFH	Aspartokinase
ACLO_1893	ENOG4105EUJ	GTP cyclohydrolase i
ACLO_1894	ENOG4105D7N	magnesium and cobalt transport protein CorA
ACLO_1895	ENOG4105D7Q	type ii secretion system
ACLO_1896	ENOG4107QHF	type ii secretion system protein e
ACLO_1899	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
ACLO_1900	ENOG4105C0P	Mg chelatase subunit ChlI
ACLO_1902	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
ACLO_1903	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
ACLO_1904	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
ACLO_1906	ENOG4105CSR	polyphosphate kinase 2
ACLO_1907	ENOG4105CSR	polyphosphate kinase 2
ACLO_1909	ENOG4105VCQ	rubredoxin
ACLO_1912	ENOG4105DFP	Integrase
ACLO_1913	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
ACLO_1948	ENOG4108VWS	Yaeq family
ACLO_1952	ENOG4105C28	cystathionine
ACLO_1956	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
ACLO_1957	ENOG4105WQG	acetyltransferase
ACLO_1959	ENOG4105D7X	high-affinity nickel-transporter
ACLO_1962	ENOG4105D65	subunit l
ACLO_1963	ENOG4108ZE9	Monovalent cation H antiporter subunit C
ACLO_1964	ENOG4107R4Z	monovalent cation h antiporter subunit d
ACLO_1965	ENOG4105SC1	monovalent cation H antiporter subunit E
ACLO_1966	ENOG4105W4C	monovalent cation H antiporter subunit F
ACLO_1967	ENOG4105KJM	monovalent cation h antiporter subunit g
ACLO_1968	ENOG4105CHR	reductase
ACLO_1970	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
ACLO_1971	ENOG4105C8Q	Methyl-accepting chemotaxis
ACLO_1972	ENOG4107XTP	(EAL) domain protein
ACLO_1973	ENOG4105D7T	ABC transporter
ACLO_1977	ENOG4108IFG	nitrite reductase, (NAD(P)H)
ACLO_1987	ENOG41084IH	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
ACLO_1988	ENOG4105C8Q	Methyl-accepting chemotaxis
ACLO_1990	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
ACLO_2018	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
ACLO_2019	ENOG4105D64	Mechanosensitive ion channel
ACLO_2025	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
ACLO_2028	ENOG4105C58	cytochrome c oxidase accessory protein ccog
ACLO_2029	ENOG4105BZU	Histidine kinase
ACLO_2030	ENOG4107VQW	regulatoR
ACLO_2032	ENOG4107QKV	phosphomannomutase
ACLO_2038	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
ACLO_2041	ENOG4105CE1	Ferrous iron transport protein b
ACLO_2044	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
ACLO_2045	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
ACLO_2046	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
ACLO_2047	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
ACLO_2048	ENOG4105F4G	Membrane
ACLO_2050	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
ACLO_2061	ENOG41082XB	radical SAM domain protein
ACLO_2062	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
ACLO_2064	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
ACLO_2067	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
ACLO_2069	ENOG4105VB9	50S ribosomal protein l28
ACLO_2072	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
ACLO_2073	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
ACLO_2074	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
ACLO_2075	ENOG4105DKP	glycosyl transferase, family 9
ACLO_2078	ENOG4107R51	Glycosyl transferase, family 2
ACLO_2081	ENOG4105CPK	Glycosyl transferase (Group 1
ACLO_2082	ENOG4107S6X	Glycosyl transferase, family 2
ACLO_2085	ENOG4108RJ9	Glycosyl transferase, family 2
ACLO_2086	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
ACLO_2089	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
ACLO_2090	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
ACLO_2094	ENOG4105DKP	glycosyl transferase, family 9
ACLO_2096	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
ACLO_2098	ENOG4105BZ8	glutamate synthase
ACLO_2099	ENOG4105CBC	glutamate synthase
ACLO_2113	ENOG4105C5E	polysaccharide biosynthesis protein
ACLO_2114	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
ACLO_2115	ENOG4105ESV	Glycosyl transferase, family 4
ACLO_2128	ENOG4105K64	Glycosyl transferase, family 2
ACLO_2130	ENOG4108RT7	Glycosyl transferase, family 2
ACLO_2131	ENOG410650X	lipopolysaccharide core region biosynthetic process
ACLO_2132	ENOG4108UW5	maltose o-acetyltransferase
ACLO_2135	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
ACLO_2136	ENOG4105F0R	Cytidylyltransferase
ACLO_2139	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
ACLO_2143	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
ACLO_2144	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
ACLO_2145	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
ACLO_2146	ENOG4105M7K	Involved in the transcription termination process (By similarity)
ACLO_2147	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
ACLO_2153	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
ACLO_2157	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
ACLO_2160	ENOG4105GVR	general secretion pathway protein D
ACLO_2161	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
ACLO_2162	ENOG4105DX0	Hemolysin A
ACLO_2163	ENOG4105DTN	riboflavin biosynthesis protein ribF
ACLO_2164	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
ACLO_2165	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ACLO_2167	ENOG4105CQB	FAD linked oxidase domain protein
ACLO_2168	ENOG4107S2Z	UPF0761 membrane protein
ACLO_2176	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
ACLO_2177	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
ACLO_2178	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
ACLO_2181	ENOG4105DJG	MaoC domain protein dehydratase
ACLO_2185	ENOG4105C8Q	Methyl-accepting chemotaxis
ACLO_2186	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
ACLO_2187	ENOG4107XC4	flavin reductase domain protein, FMN-binding
ACLO_2193	ENOG4105D7B	Flagellar biosynthesis protein flha
ACLO_2194	ENOG4105DTJ	flagellar hook-associated protein
ACLO_2195	ENOG4108JIR	Flagellum-specific ATP synthase
ACLO_2197	ENOG4105D00	flagellar biosynthetic protein flhB
ACLO_2200	ENOG4108ZC9	flagellar basal-body rod protein flgc
ACLO_2201	ENOG41084DA	flagellar hook-basal body complex protein fliE
ACLO_2203	ENOG4107R21	site-determining protein
ACLO_2204	ENOG4105FZW	flagellar biosynthesis regulator FlhF
ACLO_2209	ENOG4105E14	MotA TolQ exbB proton channel
ACLO_2210	ENOG4105DD5	Flagellar motor switch protein
ACLO_2214	ENOG4105BZE	flagellar hook protein, FlgE
ACLO_2215	ENOG4108JQA	flagellar
ACLO_2217	ENOG4105DD5	Flagellar motor switch protein
ACLO_2219	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
ACLO_2220	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
ACLO_2221	ENOG4105Q75	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
ACLO_2222	ENOG4105CGA	flagellar basal-body rod protein FlgG
ACLO_2225	ENOG4105CGA	flagellar basal-body rod protein FlgG
ACLO_2228	ENOG4105V3S	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
ACLO_2230	ENOG4105K5M	30s ribosomal protein S16
ACLO_2231	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ACLO_2233	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
ACLO_2235	ENOG4105EGD	dinuclear metal center protein, YbgI family
ACLO_2236	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
ACLO_2238	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
ACLO_2240	ENOG4105CFP	Peptidase U32
ACLO_2241	ENOG41080BE	Methyl-accepting chemotaxis sensory transducer
ACLO_2241	ENOG41080BE	Methyl-accepting chemotaxis sensory transducer
ACLO_2242	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
ACLO_2243	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
ACLO_2244	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
ACLO_2245	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
ACLO_2246	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
ACLO_2259	ENOG4105BZU	Histidine kinase
ACLO_2264	ENOG4107S1Q	Phosphatase
ACLO_2276	ENOG4105DFP	Integrase
ACLO_2279	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
ACLO_2280	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
ACLO_2281	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
ACLO_2282	ENOG4108VZM	50s ribosomal protein L10
ACLO_2283	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
ACLO_2284	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
ACLO_2285	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
ACLO_2288	ENOG41086AR	50S ribosomal protein L33
ACLO_2289	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
ACLO_2294	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
ACLO_2295	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
ACLO_2296	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
ACLO_2298	ENOG4108JQC	penicillin-binding protein 1A
ACLO_2299	ENOG4105C5F	glutamine synthetase
ACLO_2301	ENOG4105BZU	Histidine kinase
ACLO_2302	ENOG4108ZEX	molybdopterin converting factor, subunit 2
ACLO_2304	ENOG4108XUR	Pfam:DUF178
ACLO_2305	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
ACLO_2307	ENOG4105CNI	cell division protein FtsW
ACLO_2308	ENOG4105CJN	penicillin-binding protein
ACLO_2309	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
ACLO_2317	ENOG4105DDQ	anthranilate synthase
ACLO_2320	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
ACLO_2328	ENOG4105BZU	Histidine kinase
ACLO_2332	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
ACLO_2333	ENOG4107T5V	SNARE associated Golgi
ACLO_2335	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
ACLO_2336	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
ACLO_2338	ENOG4107QYE	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
ACLO_2339	ENOG4105C7B	Threonine dehydratase
ACLO_2340	ENOG4107WJT	it plays a direct role in the translocation of protons across the membrane (By similarity)
ACLO_2342	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
ACLO_2343	ENOG4105CAS	nag kinase
ACLO_2344	ENOG4107QID	Threonine synthase
ACLO_2346	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
ACLO_2349	ENOG4107YV6	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
ACLO_2351	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
ACLO_2352	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
ACLO_2354	ENOG4107SPB	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
ACLO_2355	ENOG4105CHR	reductase
ACLO_2356	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
ACLO_2357	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
ACLO_2358	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
ACLO_2359	ENOG4105K59	histidine triad (HIT) protein
ACLO_2360	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
ACLO_2361	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
ACLO_2362	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
ACLO_2363	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
ACLO_2364	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
ACLO_2365	ENOG4108JQ1	Dehydrogenase
ACLO_2366	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
ACLO_2367	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
ACLO_2368	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
ACLO_2369	ENOG4105MGB	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
ACLO_2370	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
ACLO_2372	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
ACLO_2374	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
ACLO_2377	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
ACLO_2379	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
ACLO_2381	ENOG4105YIC	Major outer membrane protein
ACLO_2387	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
ACLO_2395	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
ACLO_2396	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
ACLO_2397	ENOG4107Z7S	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
ACLO_2398	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
ACLO_2399	ENOG4105C4R	Atp-dependent dna helicase
ACLO_2400	ENOG4105DUM	transcriptional regulator, lysR family
ACLO_2401	ENOG4105N5T	Radical SAM Protein
ACLO_2402	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
ACLO_2403	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
ACLO_2404	ENOG4105C3M	thioredoxin reductase
ACLO_2405	ENOG4105K63	Thioredoxin
ACLO_2406	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
ACLO_2411	ENOG4107TT5	NLP P60 protein
ACLO_2412	ENOG4107TT5	NLP P60 protein
ACLO_2415	ENOG4107YJQ	MAF-like protein
ACLO_2416	ENOG4105CA0	peroxidase
ACLO_2417	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
ACLO_2418	ENOG4105CIH	Imidazole acetol-phosphate transaminase
ACLO_2419	ENOG4105CQC	Prephenate dehydratase
ACLO_2420	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
ACLO_2421	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
ACLO_2422	ENOG4105CP7	Triose-phosphate isomerase
ACLO_2423	ENOG4105BZA	Phosphoglycerate kinase
ACLO_2425	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
ACLO_2427	ENOG4105C75	arginyL-tRNA synthetase
ACLO_2428	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
ACLO_2429	ENOG4105WMR	Protein CrcB homolog
ACLO_2430	ENOG4105E9Q	Acyl-transferase
ACLO_2432	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
ACLO_2433	ENOG4105VR9	phosphoribosylformylglycinamidine synthase
ACLO_2434	ENOG4105C8V	SAICAR synthetase
ACLO_2435	ENOG4105CN1	protease
ACLO_2438	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
ACLO_2441	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
ACLO_2447	ENOG4105C01	Dihydroxy-acid dehydratase
ACLO_2448	ENOG4105C0H	protease
ACLO_2452	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
ACLO_2453	ENOG4105CGD	Nad-dependent epimerase dehydratase
ACLO_2456	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
ACLO_2458	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
ACLO_2460	ENOG4105CIH	Imidazole acetol-phosphate transaminase
ACLO_2461	ENOG4107XPA	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
ACLO_2463	ENOG41081FY	multiple antibiotic resistance (MarC)-related
ACLO_2464	ENOG4105F0R	Cytidylyltransferase
ACLO_2465	ENOG4108K7V	UPF0284 protein
ACLO_2468	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
ACLO_2469	ENOG4105K63	Thioredoxin
ACLO_2470	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
ACLO_2473	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
ACLO_2476	ENOG4105BZU	Histidine kinase
ACLO_2477	ENOG4105DJ4	phosphatidylserine decarboxylase
ACLO_2479	ENOG4105CA3	membrane-bound lytic murein transglycosylase
ACLO_2481	ENOG4105CFG	Acts as a chaperone (By similarity)
ACLO_2482	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ACLO_2484	ENOG4105H1G	trap transporter solute receptor taxi family
ACLO_2486	ENOG4105WH1	Two component transcriptional regulator luxr family
ACLO_2488	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
ACLO_2491	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
ACLO_2492	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
ACLO_2493	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
ACLO_2495	ENOG4105CQR	helicase
ACLO_2496	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
ACLO_2498	ENOG4105I03	Flagellin
ACLO_2502	ENOG4105F0R	Cytidylyltransferase
ACLO_2505	ENOG4107SE4	UDP-N-acetylglucosamine 2-epimerase
ACLO_2509	ENOG4105EWK	phytoene
ACLO_2510	ENOG4105D2T	synthase
ACLO_2512	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
ACLO_2514	ENOG4105CB5	ATP-dependent DNA helicase recG
ACLO_2516	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
ACLO_2517	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
ACLO_2520	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
ACLO_2524	ENOG4105E63	Pfam:DUF178
ACLO_2526	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
ACLO_2527	ENOG4105C8S	subunit m
ACLO_2528	ENOG4105D65	subunit l
ACLO_2529	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
ACLO_2531	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
ACLO_2532	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
ACLO_2536	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
ACLO_2537	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
ACLO_2538	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
ACLO_2539	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
ACLO_2540	ENOG4105DHM	ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis (By similarity)
ACLO_2545	ENOG4105CHH	sulfate transporter
ACLO_2546	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
ACLO_2548	ENOG4105C8J	)-transporter
ACLO_2550	ENOG4105WPN	DNA integration recombination invertion protein
ACLO_2552	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
ACLO_2553	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
ACLO_2554	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
ACLO_2558	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
ACLO_2561	ENOG4105C58	cytochrome c oxidase accessory protein ccog
ACLO_2562	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
ACLO_2563	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
ACLO_2569	ENOG4105C0B	DNA polymerase III (alpha subunit)
ACLO_2570	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
ACLO_2573	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
ACLO_2580	ENOG4105HFZ	Membrane
ACLO_2582	ENOG4105NU9	Preprotein translocase subunit SecG
ACLO_2584	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
ACLO_2585	ENOG4107VCP	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
ACLO_2587	ENOG4105D8G	Major Facilitator superfamily
ACLO_2588	ENOG4105EGS	Mechanosensitive ion channel
ACLO_2590	ENOG410802Z	Protein of unknown function (DUF328)
ACLO_2591	ENOG4105K5B	UPF0225 protein
ACLO_2596	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
ACLO_2598	ENOG4105C7K	acetolactate synthase
ACLO_2599	ENOG4108V0P	LemA family
ACLO_2602	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
ACLO_2604	ENOG4108RMU	ferritin dps family protein
ACLO_2606	ENOG4105C2C	drug resistance transporter, Bcr CflA
ACLO_2607	ENOG4105C8Q	Methyl-accepting chemotaxis
ACLO_2616	ENOG4105CBX	hi0933 family
ACLO_2621	ENOG4105C6T	cysteine synthase
ACLO_2624	ENOG4105C11	sulfate adenylyltransferase), subunit 2
ACLO_2625	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
ACLO_2626	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
ACLO_2627	ENOG4105C9B	Cysteine desulfurase
ACLO_2630	ENOG4107RN3	metallophosphoesterase
ACLO_2631	ENOG4107Y70	Heat shock protein
ACLO_2635	ENOG4108IJ6	ABC transporter
ACLO_2637	ENOG4108I5D	sulfate abc transporter
ACLO_2638	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
ACLO_2644	ENOG4105CI3	gtp-binding protein typa
ACLO_2647	ENOG41080IJ	Diacylglycerol kinase
ACLO_2653	ENOG41066VF	YeeE YedE family protein
ACLO_2655	ENOG4107R2U	Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity)
ACLO_2656	ENOG4105CSV	Glutaminase
ACLO_2657	ENOG4105EN6	Membrane
ACLO_2659	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
ACLO_2660	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
ACLO_a0001	ENOG4105CDU	Replicative dna helicase
ACLO_a0003	ENOG4105FA0	parb-like partition protein
ACLO_a0004	ENOG4107QJE	Chromosome Partitioning Protein
ACLO_a0006	ENOG4105D05	Receptor
ACLO_a0013	ENOG4105D05	Receptor
ACLO_a0016	ENOG4105ETX	regulatoR
ACLO_a0018	ENOG4105CAF	HipA N-terminal domain protein
ACLO_a0028	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
ACLO_a0029	ENOG4105C8Q	Methyl-accepting chemotaxis
ACLO_a0030	ENOG4105C8Q	Methyl-accepting chemotaxis
ACLO_a0034	ENOG4105C8Q	Methyl-accepting chemotaxis
ACLO_a0036	ENOG4105CBS	Chea signal transduction histidine kinase
ACLO_a0043	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
ACLO_a0046	ENOG4105E4P	ATPase (AAA
ACLO_a0062	ENOG4108W8W	CRISPR-associated RAMP protein, Csm3 family
ACLO_a0069	ENOG4105CAF	HipA N-terminal domain protein
ACLO_a0071	ENOG41084EC	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
ACLO_a0081	ENOG41062JF	Transcriptional regulator
ACLO_a0086	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
ACLO_a0090	ENOG4108UAJ	Transcriptional regulator
ACLO_a0092	ENOG4108JJA	ABC, transporter
ACLO_a0093	ENOG4105CDV	Ompa motb domain protein
ACLO_a0094	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
ACLO_a0100	ENOG4105BZU	Histidine kinase
ACLO_a0108	ENOG41075H3	AraC family transcriptional regulator
ACLO_a0112	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
ACLO_a0117	ENOG4105EQD	regulatoR
ACLO_a0118	ENOG4105BZU	Histidine kinase
ACLO_a0121	ENOG4105C9Q	fumarate hydratase class II
ACLO_a0129	ENOG4105C8Q	Methyl-accepting chemotaxis
ACLO_a0130	ENOG4105BZU	Histidine kinase
ACLO_a0131	ENOG4105CQC	Prephenate dehydratase
ACLO_a0134	ENOG41063V1	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
ACLO_a0135	ENOG4108JNI	Alpha beta hydrolase
ACLO_a0136	ENOG4105DEN	Luciferase family
ACLO_a0139	ENOG4105DF3	Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds (By similarity)
ACLO_a0140	ENOG4105DIV	Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD( ) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds (By similarity)
ACLO_a0145	ENOG4107TVJ	,Oxidoreductase FAD NAD(P)-binding
ACLO_a0149	ENOG4105HF0	Membrane
ACLO_a0157	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
ACLO_a0158	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
ACLO_a0159	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)