locus-tag	class	description
ADFLV_0001	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ADFLV_0002	COG0592	DNA-directed DNA polymerase activity
ADFLV_0003	COG0187	DNA topoisomerase II activity
ADFLV_0004	COG0492	ferredoxin-NADP+ reductase activity
ADFLV_0005	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ADFLV_0017	COG0582	viral genome integration into host DNA
ADFLV_0019	COG1238	metal cluster binding
ADFLV_0021	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ADFLV_0026	COG1053	succinate dehydrogenase
ADFLV_0027	COG0667	Aldo Keto reductase
ADFLV_0030	COG4208	sulfate ABC transporter
ADFLV_0033	COG0500	methyltransferase
ADFLV_0034	COG1120	ATPase activity
ADFLV_0038	COG3842	ATPase activity
ADFLV_0043	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
ADFLV_0044	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
ADFLV_0046	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
ADFLV_0050	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
ADFLV_0051	COG0633	Ferredoxin
ADFLV_0055	COG0716	FMN binding
ADFLV_0062	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
ADFLV_0066	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
ADFLV_0067	COG2249	NAD(P)H dehydrogenase (quinone) activity
ADFLV_0068	COG1733	regulation of RNA biosynthetic process
ADFLV_0072	COG0426	domain, Protein
ADFLV_0075	COG1280	lysine exporter protein (LysE YggA)
ADFLV_0079	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ADFLV_0086	COG0840	transmembrane signaling receptor activity
ADFLV_0087	COG0564	pseudouridine synthase activity
ADFLV_0088	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ADFLV_0089	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ADFLV_0090	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ADFLV_0096	COG2954	triphosphatase activity
ADFLV_0097	COG1151	hydroxylamine reductase activity
ADFLV_0100	COG2885	chlorophyll binding
ADFLV_0101	COG0052	Belongs to the universal ribosomal protein uS2 family
ADFLV_0102	COG0604	alcohol dehydrogenase
ADFLV_0103	COG1733	regulation of RNA biosynthetic process
ADFLV_0104	COG0390	transport system, permease component
ADFLV_0106	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ADFLV_0107	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ADFLV_0112	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ADFLV_0115	COG0745	RESPONSE REGULATOR receiver
ADFLV_0116	COG3852	Histidine kinase
ADFLV_0117	COG1556	Lactate utilization protein
ADFLV_0118	COG1139	Iron-sulfur cluster binding protein
ADFLV_0119	COG0247	lactate metabolic process
ADFLV_0121	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ADFLV_0122	COG0511	ligase activity, forming carbon-carbon bonds
ADFLV_0123	COG0439	Biotin carboxylase
ADFLV_0124	COG0513	Belongs to the DEAD box helicase family
ADFLV_0125	COG0306	phosphate transporter
ADFLV_0127	COG0367	asparagine synthase
ADFLV_0129	COG0778	Nitroreductase
ADFLV_0130	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ADFLV_0132	COG1053	succinate dehydrogenase
ADFLV_0134	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ADFLV_0136	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
ADFLV_0136	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ADFLV_0137	COG1187	pseudouridine synthase activity
ADFLV_0138	COG0517	IMP dehydrogenase activity
ADFLV_0138	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ADFLV_0139	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ADFLV_0140	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ADFLV_0141	COG0107	imidazoleglycerol-phosphate synthase activity
ADFLV_0144	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ADFLV_0145	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ADFLV_0146	COG0724	RNA recognition motif
ADFLV_0147	COG0745	RESPONSE REGULATOR receiver
ADFLV_0148	COG0642	Histidine kinase
ADFLV_0155	COG0534	Mate efflux family protein
ADFLV_0156	COG0789	Transcriptional regulator
ADFLV_0157	COG1335	isochorismatase
ADFLV_0158	COG0460	homoserine dehydrogenase
ADFLV_0159	COG0436	Aminotransferase
ADFLV_0162	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ADFLV_0163	COG0254	rRNA binding
ADFLV_0164	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ADFLV_0182	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
ADFLV_0184	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ADFLV_0185	COG0237	dephospho-CoA kinase activity
ADFLV_0186	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
ADFLV_0187	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ADFLV_0188	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ADFLV_0192	COG2353	YceI-like domain
ADFLV_0193	COG1846	Transcriptional regulator
ADFLV_0194	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ADFLV_0195	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
ADFLV_0196	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ADFLV_0198	COG0505	Belongs to the CarA family
ADFLV_0199	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ADFLV_0201	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ADFLV_0201	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ADFLV_0204	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ADFLV_0205	COG0489	protein tyrosine kinase activity
ADFLV_0207	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ADFLV_0207	COG0140	phosphoribosyl-ATP diphosphatase activity
ADFLV_0212	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ADFLV_0214	COG1410	methionine synthase
ADFLV_0214	COG0646	methionine synthase
ADFLV_0215	COG0697	spore germination
ADFLV_0217	COG1979	alcohol dehydrogenase
ADFLV_0218	COG3647	Membrane
ADFLV_0221	COG1686	Belongs to the peptidase S11 family
ADFLV_0224	COG1854	S-ribosylhomocysteine lyase activity
ADFLV_0232	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ADFLV_0237	COG1013	pyruvate-flavodoxin oxidoreductase activity
ADFLV_0238	COG0674	pyruvate-flavodoxin oxidoreductase activity
ADFLV_0240	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ADFLV_0241	COG0546	phosphoglycolate phosphatase activity
ADFLV_0243	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ADFLV_0244	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ADFLV_0245	COG5002	protein histidine kinase activity
ADFLV_0248	COG0704	Plays a role in the regulation of phosphate uptake
ADFLV_0249	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ADFLV_0250	COG0581	inorganic phosphate transmembrane transporter activity
ADFLV_0251	COG0573	inorganic phosphate transmembrane transporter activity
ADFLV_0252	COG2200	EAL domain
ADFLV_0252	COG2203	Gaf domain
ADFLV_0252	COG2199	diguanylate cyclase activity
ADFLV_0253	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ADFLV_0255	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ADFLV_0256	COG0268	Binds directly to 16S ribosomal RNA
ADFLV_0257	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ADFLV_0259	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ADFLV_0260	COG0746	molybdenum cofactor guanylyltransferase activity
ADFLV_0262	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ADFLV_0263	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ADFLV_0264	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ADFLV_0265	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ADFLV_0271	COG0575	Belongs to the CDS family
ADFLV_0272	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ADFLV_0276	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ADFLV_0277	COG0023	Translation Initiation Factor
ADFLV_0278	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ADFLV_0278	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ADFLV_0279	COG1324	tolerance protein
ADFLV_0280	COG2022	thiamine diphosphate biosynthetic process
ADFLV_0285	COG0582	viral genome integration into host DNA
ADFLV_0302	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
ADFLV_0312	COG0745	RESPONSE REGULATOR receiver
ADFLV_0315	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ADFLV_0317	COG4191	Histidine kinase
ADFLV_0318	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ADFLV_0320	COG2084	Dehydrogenase
ADFLV_0323	COG1346	cytolysis
ADFLV_0324	COG0640	Transcriptional regulator
ADFLV_0326	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ADFLV_0327	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ADFLV_0330	COG1742	UPF0060 membrane protein
ADFLV_0331	COG0659	secondary active sulfate transmembrane transporter activity
ADFLV_0335	COG4589	Belongs to the CDS family
ADFLV_0339	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
ADFLV_0344	COG0666	response to abiotic stimulus
ADFLV_0345	COG0004	ammonium transporteR
ADFLV_0347	COG0004	ammonium transporteR
ADFLV_0349	COG0418	dihydroorotase activity
ADFLV_0350	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ADFLV_0351	COG1706	bacterial-type flagellum-dependent cell motility
ADFLV_0358	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
ADFLV_0360	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
ADFLV_0363	COG0037	tRNA processing
ADFLV_0364	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ADFLV_0365	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ADFLV_0366	COG0601	transmembrane transport
ADFLV_0368	COG0736	holo-[acyl-carrier-protein] synthase activity
ADFLV_0369	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ADFLV_0371	COG0560	Phosphoserine phosphatase
ADFLV_0373	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
ADFLV_0374	COG3248	Nucleoside-binding outer membrane protein
ADFLV_0376	COG1393	Belongs to the ArsC family
ADFLV_0377	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ADFLV_0378	COG0343	queuine tRNA-ribosyltransferase activity
ADFLV_0380	COG0436	Aminotransferase
ADFLV_0383	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ADFLV_0385	COG2861	carbohydrate metabolic process
ADFLV_0386	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ADFLV_0387	COG0557	exoribonuclease II activity
ADFLV_0390	COG0360	Binds together with S18 to 16S ribosomal RNA
ADFLV_0391	COG0629	single-stranded DNA binding
ADFLV_0392	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ADFLV_0393	COG0215	cysteine-tRNA ligase activity
ADFLV_0394	COG0195	Participates in both transcription termination and antitermination
ADFLV_0396	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ADFLV_0397	COG2121	Domain of unknown function (DUF374)
ADFLV_0399	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
ADFLV_0401	COG0288	reversible hydration of carbon dioxide
ADFLV_0402	COG0156	8-amino-7-oxononanoate synthase activity
ADFLV_0403	COG0792	nuclease activity
ADFLV_0409	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ADFLV_0411	COG0540	Belongs to the ATCase OTCase family
ADFLV_0412	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ADFLV_0416	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
ADFLV_0417	COG1687	branched-chain amino acid
ADFLV_0418	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ADFLV_0419	COG0416	fatty acid biosynthetic process
ADFLV_0420	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ADFLV_0422	COG0105	UTP biosynthetic process
ADFLV_0424	COG0450	alkyl hydroperoxide reductase
ADFLV_0425	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ADFLV_0427	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ADFLV_0428	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ADFLV_0429	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ADFLV_0431	COG0181	hydroxymethylbilane synthase activity
ADFLV_0434	COG2828	Protein conserved in bacteria
ADFLV_0435	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ADFLV_0437	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
ADFLV_0439	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ADFLV_0446	COG2207	Transcriptional regulator
ADFLV_0446	COG3708	Transcriptional regulator
ADFLV_0447	COG0514	ATP-dependent DNA helicase (RecQ)
ADFLV_0449	COG0640	Transcriptional regulator
ADFLV_0450	COG2217	Heavy metal translocating P-type atpase
ADFLV_0453	COG1451	nucleotide metabolic process
ADFLV_0454	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
ADFLV_0456	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ADFLV_0457	COG1053	succinate dehydrogenase
ADFLV_0459	COG1007	ATP synthesis coupled electron transport
ADFLV_0461	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ADFLV_0462	COG0713	ATP synthesis coupled electron transport
ADFLV_0463	COG0839	Belongs to the complex I subunit 6 family
ADFLV_0464	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ADFLV_0465	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ADFLV_0466	COG1034	ATP synthesis coupled electron transport
ADFLV_0467	COG0372	Belongs to the citrate synthase family
ADFLV_0470	COG0649	NAD binding
ADFLV_0470	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ADFLV_0471	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ADFLV_0472	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ADFLV_0473	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ADFLV_0474	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ADFLV_0475	COG3610	response to peptide
ADFLV_0476	COG2966	Psort location CytoplasmicMembrane, score
ADFLV_0482	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ADFLV_0484	COG3706	GGDEF domain
ADFLV_0489	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ADFLV_0493	COG0840	transmembrane signaling receptor activity
ADFLV_0497	COG3043	anaerobic respiration
ADFLV_0498	COG0348	domain, Protein
ADFLV_0499	COG0437	4 iron, 4 sulfur cluster binding
ADFLV_0500	COG0243	molybdopterin cofactor binding
ADFLV_0501	COG3287	FIST C domain
ADFLV_0501	COG2200	EAL domain
ADFLV_0501	COG2199	diguanylate cyclase activity
ADFLV_0502	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ADFLV_0505	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ADFLV_0506	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ADFLV_0507	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ADFLV_0509	COG2404	hydrolase activity, acting on ester bonds
ADFLV_0510	COG1832	CoA-binding protein
ADFLV_0511	COG0642	Histidine kinase
ADFLV_0512	COG0745	RESPONSE REGULATOR receiver
ADFLV_0513	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ADFLV_0514	COG0191	fructose-bisphosphate aldolase activity
ADFLV_0515	COG0745	RESPONSE REGULATOR receiver
ADFLV_0516	COG0642	Histidine kinase
ADFLV_0520	COG0811	peptide transport
ADFLV_0522	COG4191	Histidine kinase
ADFLV_0525	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ADFLV_0527	COG0142	geranyltranstransferase activity
ADFLV_0528	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ADFLV_0529	COG0442	prolyl-tRNA aminoacylation
ADFLV_0530	COG0668	transmembrane transport
ADFLV_0534	COG0815	Transfers the fatty acyl group on membrane lipoproteins
ADFLV_0535	COG1862	Preprotein translocase
ADFLV_0536	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ADFLV_0537	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ADFLV_0540	COG0495	leucyl-tRNA aminoacylation
ADFLV_0542	COG0285	dihydrofolate synthase activity
ADFLV_0549	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
ADFLV_0553	COG4399	Belongs to the UPF0754 family
ADFLV_0556	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ADFLV_0559	COG3292	Two component regulator propeller
ADFLV_0559	COG0745	RESPONSE REGULATOR receiver
ADFLV_0559	COG2205	protein histidine kinase activity
ADFLV_0561	COG4251	negative regulation of phosphorylation
ADFLV_0561	COG2203	Gaf domain
ADFLV_0561	COG5001	Diguanylate cyclase
ADFLV_0561	COG3706	GGDEF domain
ADFLV_0563	COG0745	RESPONSE REGULATOR receiver
ADFLV_0564	COG0642	Histidine kinase
ADFLV_0565	COG2081	HI0933 family
ADFLV_0566	COG0840	transmembrane signaling receptor activity
ADFLV_0568	COG0840	transmembrane signaling receptor activity
ADFLV_0570	COG1692	metallophosphoesterase
ADFLV_0573	COG2226	methyltransferase
ADFLV_0574	COG1570	exodeoxyribonuclease VII activity
ADFLV_0577	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ADFLV_0579	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
ADFLV_0580	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ADFLV_0582	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ADFLV_0583	COG0459	protein refolding
ADFLV_0584	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
ADFLV_0586	COG0745	RESPONSE REGULATOR receiver
ADFLV_0587	COG1408	metallophosphoesterase
ADFLV_0592	COG1136	(ABC) transporter
ADFLV_0595	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ADFLV_0599	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ADFLV_0600	COG0352	thiamine-phosphate diphosphorylase activity
ADFLV_0601	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ADFLV_0603	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ADFLV_0604	COG2264	protein methyltransferase activity
ADFLV_0605	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ADFLV_0606	COG3437	response regulator, receiver
ADFLV_0606	COG0784	Response regulator, receiver
ADFLV_0608	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ADFLV_0612	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ADFLV_0618	COG1132	(ABC) transporter
ADFLV_0621	COG3706	GGDEF domain
ADFLV_0622	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ADFLV_0623	COG1090	epimerase
ADFLV_0624	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ADFLV_0626	COG0481	GTPase activity
ADFLV_0629	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ADFLV_0631	COG0482	sulfurtransferase activity
ADFLV_0632	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ADFLV_0633	COG0006	proline dipeptidase activity
ADFLV_0634	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ADFLV_0635	COG0402	S-adenosylhomocysteine deaminase activity
ADFLV_0636	COG0616	signal peptide processing
ADFLV_0638	COG0280	phosphate acetyltransferase
ADFLV_0639	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ADFLV_0640	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ADFLV_0641	COG2176	DNA-directed DNA polymerase activity
ADFLV_0645	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ADFLV_0647	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
ADFLV_0649	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ADFLV_0651	COG0745	RESPONSE REGULATOR receiver
ADFLV_0661	COG1058	Belongs to the CinA family
ADFLV_0661	COG1546	Belongs to the CinA family
ADFLV_0662	COG0579	oxidoreductase
ADFLV_0663	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ADFLV_0666	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ADFLV_0672	COG0714	Associated with various cellular activities
ADFLV_0673	COG0052	Belongs to the universal ribosomal protein uS2 family
ADFLV_0674	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ADFLV_0675	COG1136	(ABC) transporter
ADFLV_0677	COG0194	GDP metabolic process
ADFLV_0678	COG5001	Diguanylate cyclase
ADFLV_0678	COG5002	protein histidine kinase activity
ADFLV_0679	COG2217	Heavy metal translocating P-type atpase
ADFLV_0682	COG4608	Belongs to the ABC transporter superfamily
ADFLV_0683	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ADFLV_0686	COG1355	regulation of microtubule-based process
ADFLV_0688	COG1121	(ABC) transporter
ADFLV_0689	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ADFLV_0692	COG2996	Protein conserved in bacteria
ADFLV_0693	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ADFLV_0694	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
ADFLV_0696	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ADFLV_0698	COG0210	DNA helicase
ADFLV_0699	COG0475	glutathione-regulated potassium exporter activity
ADFLV_0699	COG0569	domain protein
ADFLV_0700	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ADFLV_0705	COG3258	Cytochrome c
ADFLV_0713	COG0693	protein deglycase activity
ADFLV_0717	COG0525	valine-tRNA ligase activity
ADFLV_0718	COG4895	conserved protein (DUF2196)
ADFLV_0719	COG1047	Peptidyl-prolyl cis-trans
ADFLV_0721	COG3706	GGDEF domain
ADFLV_0723	COG2814	Major facilitator Superfamily
ADFLV_0724	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ADFLV_0726	COG2197	response regulator
ADFLV_0728	COG2831	hemolysin activation secretion protein
ADFLV_0732	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ADFLV_0733	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ADFLV_0734	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ADFLV_0738	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ADFLV_0740	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
ADFLV_0741	COG1309	transcriptional regulator
ADFLV_0746	COG0840	transmembrane signaling receptor activity
ADFLV_0749	COG0439	Biotin carboxylase
ADFLV_0750	COG3040	lipid binding
ADFLV_0755	COG2151	metal-sulfur cluster biosynthetic enzyme
ADFLV_0756	COG2166	iron-sulfur cluster assembly
ADFLV_0757	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ADFLV_0759	COG0396	ATPase activity
ADFLV_0760	COG0719	Fe-S assembly protein
ADFLV_0761	COG4191	Histidine kinase
ADFLV_0762	COG1366	Belongs to the anti-sigma-factor antagonist family
ADFLV_0762	COG2202	Pas domain
ADFLV_0764	COG2906	2 iron, 2 sulfur cluster binding
ADFLV_0764	COG0822	iron-sulfur transferase activity
ADFLV_0764	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
ADFLV_0765	COG1280	lysine exporter protein (LysE YggA)
ADFLV_0768	COG2239	Acts as a magnesium transporter
ADFLV_0770	COG3706	GGDEF domain
ADFLV_0774	COG0165	Argininosuccinate lyase
ADFLV_0775	COG0835	chemotaxis
ADFLV_0775	COG0784	Response regulator, receiver
ADFLV_0776	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ADFLV_0777	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ADFLV_0780	COG0556	nucleotide-excision repair
ADFLV_0781	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ADFLV_0783	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ADFLV_0788	COG0698	ribose 5-phosphate isomerase
ADFLV_0789	COG0681	Belongs to the peptidase S26 family
ADFLV_0790	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ADFLV_0791	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ADFLV_0792	COG0193	aminoacyl-tRNA hydrolase activity
ADFLV_0795	COG0860	N-Acetylmuramoyl-L-alanine amidase
ADFLV_0797	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ADFLV_0799	COG1758	RNA polymerase activity
ADFLV_0800	COG0528	UMP kinase activity
ADFLV_0802	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ADFLV_0803	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ADFLV_0804	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ADFLV_0806	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ADFLV_0807	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ADFLV_0810	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ADFLV_0812	COG0305	Participates in initiation and elongation during chromosome replication
ADFLV_0815	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ADFLV_0823	COG1011	Hydrolase
ADFLV_0826	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ADFLV_0835	COG2337	Toxic component of a toxin-antitoxin (TA) module
ADFLV_0837	COG4115	mRNA cleavage
ADFLV_0838	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ADFLV_0840	COG1086	Polysaccharide biosynthesis protein
ADFLV_0842	COG1793	dna ligase
ADFLV_0843	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ADFLV_0844	COG0133	tryptophan synthase activity
ADFLV_0846	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ADFLV_0847	COG0848	biopolymer transport protein
ADFLV_0852	COG0577	efflux transmembrane transporter activity
ADFLV_0852	COG1136	(ABC) transporter
ADFLV_0853	COG0577	efflux transmembrane transporter activity
ADFLV_0853	COG1136	(ABC) transporter
ADFLV_0864	COG0114	fumarate hydratase activity
ADFLV_0870	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
ADFLV_0870	COG1918	ferrous iron import across plasma membrane
ADFLV_0871	COG1918	ferrous iron import across plasma membrane
ADFLV_0872	COG4771	TonB-dependent receptor
ADFLV_0873	COG2819	hydrolase of the alpha beta superfamily
ADFLV_0874	COG3920	Histidine kinase
ADFLV_0875	COG0784	Response regulator, receiver
ADFLV_0876	COG4771	TonB-dependent receptor
ADFLV_0879	COG0745	RESPONSE REGULATOR receiver
ADFLV_0883	COG0012	GTP binding
ADFLV_0887	COG3123	guanosine phosphorylase activity
ADFLV_0891	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ADFLV_0892	COG0585	pseudouridine synthase activity
ADFLV_0894	COG4773	Receptor
ADFLV_0895	COG0840	transmembrane signaling receptor activity
ADFLV_0896	COG0632	four-way junction helicase activity
ADFLV_0897	COG1181	Belongs to the D-alanine--D-alanine ligase family
ADFLV_0899	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ADFLV_0902	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ADFLV_0903	COG0051	transcription antitermination factor activity, RNA binding
ADFLV_0904	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ADFLV_0905	COG0088	Forms part of the polypeptide exit tunnel
ADFLV_0906	COG0089	rRNA binding
ADFLV_0907	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ADFLV_0908	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ADFLV_0909	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ADFLV_0910	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ADFLV_0911	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ADFLV_0912	COG0255	Belongs to the universal ribosomal protein uL29 family
ADFLV_0913	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ADFLV_0914	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ADFLV_0915	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ADFLV_0916	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ADFLV_0917	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ADFLV_0918	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ADFLV_0919	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ADFLV_0920	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ADFLV_0921	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ADFLV_0922	COG0200	Binds to the 23S rRNA
ADFLV_0923	COG0201	protein transport
ADFLV_0924	COG0024	Methionine aminopeptidase
ADFLV_0925	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ADFLV_0927	COG1573	uracil-dna glycosylase
ADFLV_0929	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ADFLV_0932	COG1032	radical SAM domain protein
ADFLV_0934	COG0563	adenylate kinase activity
ADFLV_0937	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ADFLV_0938	COG0322	excinuclease ABC activity
ADFLV_0940	COG3706	GGDEF domain
ADFLV_0942	COG3201	nicotinamide mononucleotide transporter
ADFLV_0943	COG0386	Belongs to the glutathione peroxidase family
ADFLV_0946	COG0840	transmembrane signaling receptor activity
ADFLV_0947	COG0840	transmembrane signaling receptor activity
ADFLV_0949	COG0745	RESPONSE REGULATOR receiver
ADFLV_0951	COG0784	Response regulator, receiver
ADFLV_0951	COG2205	protein histidine kinase activity
ADFLV_0957	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ADFLV_0959	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ADFLV_0960	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
ADFLV_0967	COG0829	nickel cation binding
ADFLV_0968	COG0402	S-adenosylhomocysteine deaminase activity
ADFLV_0969	COG2252	PERMEase
ADFLV_0972	COG4266	Belongs to the allantoicase family
ADFLV_0975	COG2351	hydroxyisourate hydrolase activity
ADFLV_0977	COG2233	PERMEase
ADFLV_0982	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
ADFLV_0982	COG3608	succinylglutamate desuccinylase aspartoacylase
ADFLV_0983	COG0831	urea catabolic process
ADFLV_0983	COG0832	Belongs to the urease beta subunit family
ADFLV_0984	COG0804	urea catabolic process
ADFLV_0985	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
ADFLV_0987	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
ADFLV_0991	COG1846	Transcriptional regulator
ADFLV_0993	COG3706	GGDEF domain
ADFLV_0994	COG0708	Exodeoxyribonuclease III
ADFLV_1001	COG0166	Belongs to the GPI family
ADFLV_1010	COG2252	PERMEase
ADFLV_1011	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
ADFLV_1013	COG2363	Small membrane protein
ADFLV_1015	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ADFLV_1016	COG2233	PERMEase
ADFLV_1017	COG1666	GTP binding
ADFLV_1019	COG0745	RESPONSE REGULATOR receiver
ADFLV_1020	COG0642	Histidine kinase
ADFLV_1024	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ADFLV_1025	COG0135	phosphoribosylanthranilate isomerase activity
ADFLV_1026	COG2176	DNA-directed DNA polymerase activity
ADFLV_1027	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ADFLV_1029	COG1013	pyruvate-flavodoxin oxidoreductase activity
ADFLV_1030	COG0674	pyruvate-flavodoxin oxidoreductase activity
ADFLV_1030	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ADFLV_1032	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
ADFLV_1033	COG0727	PFAM Uncharacterised protein family (UPF0153)
ADFLV_1035	COG0134	indole-3-glycerol-phosphate synthase activity
ADFLV_1036	COG0583	DNA-binding transcription factor activity
ADFLV_1038	COG0840	transmembrane signaling receptor activity
ADFLV_1040	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ADFLV_1041	COG0750	zinc metalloprotease
ADFLV_1042	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ADFLV_1043	COG1028	Short-chain dehydrogenase reductase Sdr
ADFLV_1044	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ADFLV_1047	COG0167	dihydroorotate dehydrogenase activity
ADFLV_1048	COG1132	(ABC) transporter
ADFLV_1049	COG0728	peptidoglycan biosynthetic process
ADFLV_1051	COG1592	Rubrerythrin
ADFLV_1053	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ADFLV_1054	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ADFLV_1062	COG1858	cytochrome C peroxidase
ADFLV_1065	COG0552	protein localization to endoplasmic reticulum
ADFLV_1066	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ADFLV_1068	COG1418	mRNA catabolic process
ADFLV_1069	COG0742	ribosomal rna small subunit methyltransferase
ADFLV_1070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ADFLV_1072	COG0300	oxidoreductase activity
ADFLV_1074	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
ADFLV_1075	COG0732	type I restriction modification DNA specificity domain
ADFLV_1079	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
ADFLV_1080	COG3258	Cytochrome c
ADFLV_1083	COG0642	Histidine kinase
ADFLV_1086	COG1610	YqeY-like protein
ADFLV_1088	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ADFLV_1089	COG0436	Aminotransferase
ADFLV_1090	COG1451	nucleotide metabolic process
ADFLV_1092	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ADFLV_1093	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ADFLV_1094	COG0519	Catalyzes the synthesis of GMP from XMP
ADFLV_1094	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ADFLV_1104	COG0697	spore germination
ADFLV_1108	COG0596	Alpha beta hydrolase
ADFLV_1109	COG0204	Acyl-transferase
ADFLV_1111	COG0531	amino acid
ADFLV_1115	COG1696	Membrane protein involved in D-alanine export
ADFLV_1116	COG0564	pseudouridine synthase activity
ADFLV_1137	COG1393	Belongs to the ArsC family
ADFLV_1139	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ADFLV_1140	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ADFLV_1141	COG2223	nitrite transmembrane transporter activity
ADFLV_1142	COG2186	Transcriptional regulator
ADFLV_1143	COG2807	transmembrane transport
ADFLV_1146	COG1028	Short-chain dehydrogenase reductase Sdr
ADFLV_1147	COG0519	Catalyzes the synthesis of GMP from XMP
ADFLV_1147	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ADFLV_1153	COG1253	flavin adenine dinucleotide binding
ADFLV_1154	COG2989	Protein conserved in bacteria
ADFLV_1156	COG0628	permease
ADFLV_1159	COG1253	flavin adenine dinucleotide binding
ADFLV_1162	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ADFLV_1170	COG1181	Belongs to the D-alanine--D-alanine ligase family
ADFLV_1171	COG0513	Belongs to the DEAD box helicase family
ADFLV_1172	COG3287	FIST C domain
ADFLV_1172	COG2199	diguanylate cyclase activity
ADFLV_1172	COG2200	EAL domain
ADFLV_1173	COG0840	transmembrane signaling receptor activity
ADFLV_1174	COG0840	transmembrane signaling receptor activity
ADFLV_1177	COG1045	serine acetyltransferase
ADFLV_1178	COG1166	arginine decarboxylase activity
ADFLV_1179	COG0124	histidyl-tRNA synthetase
ADFLV_1180	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ADFLV_1181	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ADFLV_1182	COG0163	prenyltransferase activity
ADFLV_1184	COG0359	binds to the 23S rRNA
ADFLV_1185	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
ADFLV_1186	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
ADFLV_1188	COG0084	hydrolase, TatD family'
ADFLV_1190	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ADFLV_1191	COG0131	Imidazoleglycerol-phosphate dehydratase
ADFLV_1192	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ADFLV_1195	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ADFLV_1196	COG0456	acetyltransferase
ADFLV_1198	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ADFLV_1200	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ADFLV_1201	COG3576	pyridoxamine 5-phosphate
ADFLV_1205	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ADFLV_1207	COG2897	thiosulfate sulfurtransferase activity
ADFLV_1209	COG1338	Plays a role in the flagellum-specific transport system
ADFLV_1221	COG0849	cell division
ADFLV_1222	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ADFLV_1223	COG2391	methyltransferase activity
ADFLV_1228	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ADFLV_1232	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ADFLV_1233	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ADFLV_1252	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ADFLV_1261	COG3505	Type IV secretory pathway VirD4
ADFLV_1264	COG3504	Conjugal transfer protein
ADFLV_1303	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ADFLV_1306	COG1401	restriction endodeoxyribonuclease activity
ADFLV_1308	COG1401	restriction endodeoxyribonuclease activity
ADFLV_1319	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ADFLV_1325	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ADFLV_1337	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
ADFLV_1340	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
ADFLV_1345	COG2026	Addiction module toxin, RelE StbE family
ADFLV_1351	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ADFLV_1352	COG1360	Flagellar Motor Protein
ADFLV_1353	COG0861	Integral membrane protein TerC family
ADFLV_1362	COG0842	Transport permease protein
ADFLV_1363	COG0842	Transport permease protein
ADFLV_1364	COG1131	(ABC) transporter
ADFLV_1365	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ADFLV_1366	COG0789	Transcriptional regulator
ADFLV_1367	COG0484	heat shock protein binding
ADFLV_1368	COG4191	Histidine kinase
ADFLV_1370	COG2201	protein-glutamate methylesterase activity
ADFLV_1372	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ADFLV_1372	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
ADFLV_1375	COG0776	regulation of translation
ADFLV_1377	COG0275	rRNA processing
ADFLV_1383	COG0318	PFAM AMP-dependent synthetase and ligase
ADFLV_1385	COG4865	methylaspartate mutase activity
ADFLV_1387	COG0039	L-malate dehydrogenase activity
ADFLV_1391	COG4591	ABC-type transport system involved in lipoprotein release permease component
ADFLV_1392	COG0653	protein targeting
ADFLV_1395	COG2207	Transcriptional regulator
ADFLV_1396	COG1979	alcohol dehydrogenase
ADFLV_1398	COG4191	Histidine kinase
ADFLV_1398	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ADFLV_1399	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ADFLV_1399	COG1587	Uroporphyrinogen-III synthase
ADFLV_1401	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ADFLV_1402	COG0243	molybdopterin cofactor binding
ADFLV_1403	COG2199	diguanylate cyclase activity
ADFLV_1403	COG3287	FIST C domain
ADFLV_1403	COG2200	EAL domain
ADFLV_1404	COG0515	serine threonine protein kinase
ADFLV_1404	COG2815	serine threonine protein kinase
ADFLV_1405	COG2223	nitrite transmembrane transporter activity
ADFLV_1406	COG0754	glutathionylspermidine amidase activity
ADFLV_1408	COG3706	GGDEF domain
ADFLV_1409	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ADFLV_1415	COG0745	RESPONSE REGULATOR receiver
ADFLV_1417	COG0745	RESPONSE REGULATOR receiver
ADFLV_1434	COG4804	nuclease activity
ADFLV_1444	COG0640	Transcriptional regulator
ADFLV_1469	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ADFLV_1472	COG0281	malic enzyme
ADFLV_1472	COG0280	phosphate acetyltransferase
ADFLV_1473	COG0788	formyltetrahydrofolate deformylase activity
ADFLV_1474	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ADFLV_1477	COG0745	RESPONSE REGULATOR receiver
ADFLV_1479	COG0330	HflC and HflK could
ADFLV_1483	COG1271	oxidase subunit
ADFLV_1488	COG0450	alkyl hydroperoxide reductase
ADFLV_1491	COG0811	peptide transport
ADFLV_1492	COG0848	biopolymer transport protein
ADFLV_1495	COG0419	ATPase involved in DNA repair
ADFLV_1500	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ADFLV_1501	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
ADFLV_1502	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
ADFLV_1503	COG1187	pseudouridine synthase activity
ADFLV_1509	COG4206	TonB-dependent receptor
ADFLV_1512	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ADFLV_1517	COG0667	Aldo Keto reductase
ADFLV_1518	COG0840	transmembrane signaling receptor activity
ADFLV_1521	COG0824	Thioesterase
ADFLV_1523	COG0501	Belongs to the peptidase M48B family
ADFLV_1524	COG1322	Protein conserved in bacteria
ADFLV_1526	COG2321	neutral zinc metallopeptidase
ADFLV_1531	COG0037	tRNA processing
ADFLV_1532	COG1683	Conserved Protein
ADFLV_1536	COG4251	negative regulation of phosphorylation
ADFLV_1536	COG5001	Diguanylate cyclase
ADFLV_1536	COG2203	Gaf domain
ADFLV_1536	COG3706	GGDEF domain
ADFLV_1540	COG0028	Belongs to the TPP enzyme family
ADFLV_1541	COG0440	acetolactate synthase activity
ADFLV_1542	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ADFLV_1543	COG1674	ftsk spoiiie
ADFLV_1543	COG1196	nuclear chromosome segregation
ADFLV_1545	COG1160	GTP binding
ADFLV_1546	COG0659	secondary active sulfate transmembrane transporter activity
ADFLV_1550	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ADFLV_1552	COG1185	polyribonucleotide nucleotidyltransferase activity
ADFLV_1554	COG2198	Histidine kinase
ADFLV_1554	COG0643	Histidine kinase
ADFLV_1555	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ADFLV_1556	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
ADFLV_1557	COG2201	protein-glutamate methylesterase activity
ADFLV_1559	COG0582	viral genome integration into host DNA
ADFLV_1563	COG0339	signal peptide processing
ADFLV_1564	COG2890	protein-(glutamine-N5) methyltransferase activity
ADFLV_1565	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ADFLV_1566	COG0494	nUDIX hydrolase
ADFLV_1567	COG0527	aspartate kinase activity
ADFLV_1570	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ADFLV_1571	COG0287	Prephenate dehydrogenase
ADFLV_1572	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ADFLV_1573	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
ADFLV_1574	COG0612	Peptidase, M16
ADFLV_1575	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ADFLV_1581	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
ADFLV_1583	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ADFLV_1583	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ADFLV_1588	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
ADFLV_1589	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
ADFLV_1600	COG4974	Belongs to the 'phage' integrase family
ADFLV_1613	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ADFLV_1619	COG0357	Ribosomal RNA small subunit methyltransferase G
ADFLV_1620	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ADFLV_1621	COG0113	porphobilinogen synthase activity
ADFLV_1626	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ADFLV_1626	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ADFLV_1627	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ADFLV_1628	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ADFLV_1630	COG1663	tetraacyldisaccharide 4'-kinase activity
ADFLV_1632	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ADFLV_1636	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ADFLV_1637	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ADFLV_1638	COG0805	protein transport
ADFLV_1639	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ADFLV_1646	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ADFLV_1649	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ADFLV_1653	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ADFLV_1653	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ADFLV_1654	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
ADFLV_1655	COG2200	EAL domain
ADFLV_1655	COG3287	FIST C domain
ADFLV_1655	COG2199	diguanylate cyclase activity
ADFLV_1656	COG3706	GGDEF domain
ADFLV_1657	COG1137	ATPase activity
ADFLV_1658	COG0802	atpase or kinase
ADFLV_1659	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ADFLV_1661	COG0137	argininosuccinate synthase activity
ADFLV_1663	COG0189	ligase activity
ADFLV_1667	COG0569	domain protein
ADFLV_1668	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ADFLV_1669	COG0745	RESPONSE REGULATOR receiver
ADFLV_1670	COG2205	protein histidine kinase activity
ADFLV_1672	COG4191	Histidine kinase
ADFLV_1674	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ADFLV_1676	COG0484	heat shock protein binding
ADFLV_1677	COG0133	tryptophan synthase activity
ADFLV_1681	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ADFLV_1682	COG5001	Diguanylate cyclase
ADFLV_1683	COG5001	Diguanylate cyclase
ADFLV_1683	COG3706	GGDEF domain
ADFLV_1683	COG4251	negative regulation of phosphorylation
ADFLV_1683	COG2203	Gaf domain
ADFLV_1684	COG0500	methyltransferase
ADFLV_1685	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ADFLV_1685	COG1333	cytochrome c biogenesis protein
ADFLV_1686	COG0745	RESPONSE REGULATOR receiver
ADFLV_1688	COG2195	Cleaves the N-terminal amino acid of tripeptides
ADFLV_1690	COG0840	transmembrane signaling receptor activity
ADFLV_1691	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ADFLV_1692	COG2205	protein histidine kinase activity
ADFLV_1692	COG4999	Histidine kinase
ADFLV_1692	COG3850	Histidine kinase
ADFLV_1692	COG3437	response regulator, receiver
ADFLV_1693	COG0745	RESPONSE REGULATOR receiver
ADFLV_1694	COG3437	response regulator, receiver
ADFLV_1694	COG0784	Response regulator, receiver
ADFLV_1695	COG1607	acyl-coa hydrolase
ADFLV_1696	COG0488	(ABC) transporter
ADFLV_1698	COG1979	alcohol dehydrogenase
ADFLV_1699	COG2207	Transcriptional regulator
ADFLV_1700	COG3706	GGDEF domain
ADFLV_1701	COG0745	RESPONSE REGULATOR receiver
ADFLV_1702	COG0643	Histidine kinase
ADFLV_1702	COG2198	Histidine kinase
ADFLV_1704	COG2205	protein histidine kinase activity
ADFLV_1707	COG3710	Transcriptional regulator
ADFLV_1708	COG0778	Nitroreductase
ADFLV_1712	COG2249	NAD(P)H dehydrogenase (quinone) activity
ADFLV_1713	COG1733	regulation of RNA biosynthetic process
ADFLV_1716	COG2855	membrane
ADFLV_1717	COG0583	DNA-binding transcription factor activity
ADFLV_1718	COG3706	GGDEF domain
ADFLV_1719	COG1881	PFAM PEBP family protein
ADFLV_1721	COG3706	GGDEF domain
ADFLV_1724	COG2076	Multidrug Resistance protein
ADFLV_1731	COG2824	Alkylphosphonate utilization operon protein PhnA
ADFLV_1733	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ADFLV_1734	COG0095	Lipoate-protein ligase
ADFLV_1735	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ADFLV_1736	COG0508	dehydrogenase complex catalyzes the overall conversion of
ADFLV_1737	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ADFLV_1748	COG1605	Chorismate mutase
ADFLV_1748	COG0077	Prephenate dehydratase
ADFLV_1749	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ADFLV_1750	COG1119	ATPase activity
ADFLV_1751	COG2205	protein histidine kinase activity
ADFLV_1751	COG0784	Response regulator, receiver
ADFLV_1752	COG2202	Pas domain
ADFLV_1752	COG2205	protein histidine kinase activity
ADFLV_1753	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ADFLV_1757	COG1193	negative regulation of DNA recombination
ADFLV_1759	COG0471	metal ion transport
ADFLV_1760	COG0521	Mo-molybdopterin cofactor biosynthetic process
ADFLV_1762	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ADFLV_1763	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ADFLV_1765	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ADFLV_1771	COG2274	protein secretion by the type I secretion system
ADFLV_1774	COG0745	RESPONSE REGULATOR receiver
ADFLV_1779	COG3706	GGDEF domain
ADFLV_1780	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ADFLV_1782	COG3279	Response regulator of the LytR AlgR family
ADFLV_1785	COG1233	COG1233 Phytoene dehydrogenase and related
ADFLV_1793	COG0642	Histidine kinase
ADFLV_1794	COG0745	RESPONSE REGULATOR receiver
ADFLV_1798	COG1132	(ABC) transporter
ADFLV_1799	COG0628	permease
ADFLV_1800	COG1472	Belongs to the glycosyl hydrolase 3 family
ADFLV_1805	COG1620	l-lactate permease
ADFLV_1808	COG0484	heat shock protein binding
ADFLV_1818	COG0516	GMP reductase activity
ADFLV_1818	COG0517	IMP dehydrogenase activity
ADFLV_1819	COG0154	amidase activity
ADFLV_1820	COG0203	ribosomal protein L17
ADFLV_1821	COG0202	RNA polymerase activity
ADFLV_1822	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ADFLV_1823	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ADFLV_1824	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ADFLV_1827	COG0473	3-isopropylmalate dehydrogenase activity
ADFLV_1842	COG3504	Conjugal transfer protein
ADFLV_1845	COG3505	Type IV secretory pathway VirD4
ADFLV_1854	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ADFLV_1871	COG0066	3-isopropylmalate dehydratase activity
ADFLV_1872	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ADFLV_1876	COG3123	guanosine phosphorylase activity
ADFLV_1877	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ADFLV_1880	COG0772	Belongs to the SEDS family
ADFLV_1881	COG0564	pseudouridine synthase activity
ADFLV_1882	COG0366	Alpha amylase catalytic
ADFLV_1882	COG3103	Sh3 type 3 domain protein
ADFLV_1883	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ADFLV_1884	COG2884	Cell division ATP-binding protein ftsE
ADFLV_1887	COG1671	Belongs to the UPF0178 family
ADFLV_1889	COG0488	(ABC) transporter
ADFLV_1890	COG2171	N-acyltransferase activity
ADFLV_1891	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ADFLV_1896	COG3706	GGDEF domain
ADFLV_1898	COG0309	Hydrogenase expression formation protein (HypE)
ADFLV_1902	COG0298	carbon dioxide binding
ADFLV_1903	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
ADFLV_1906	COG0840	transmembrane signaling receptor activity
ADFLV_1908	COG2081	HI0933 family
ADFLV_1912	COG0439	Biotin carboxylase
ADFLV_1918	COG2354	Protein conserved in bacteria
ADFLV_1920	COG2814	Major facilitator Superfamily
ADFLV_1924	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ADFLV_1924	COG0301	tRNA thio-modification
ADFLV_1929	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
ADFLV_1934	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
ADFLV_1937	COG1518	maintenance of DNA repeat elements
ADFLV_1948	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
ADFLV_1949	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
ADFLV_1951	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
ADFLV_1954	COG1049	propionate catabolic process, 2-methylcitrate cycle
ADFLV_1957	COG0242	peptide deformylase activity
ADFLV_1958	COG1022	Amp-dependent synthetase and ligase
ADFLV_1959	COG0183	Belongs to the thiolase family
ADFLV_1960	COG1250	3-hydroxyacyl-CoA dehydrogenase
ADFLV_1960	COG1024	Enoyl-CoA hydratase
ADFLV_1961	COG1960	acyl-CoA dehydrogenase activity
ADFLV_1973	COG0217	transcriptional regulatory protein
ADFLV_1974	COG2853	Lipoprotein
ADFLV_1977	COG1611	Belongs to the LOG family
ADFLV_1978	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ADFLV_1979	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ADFLV_1983	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
ADFLV_1986	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ADFLV_1988	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ADFLV_1989	COG0477	Major facilitator Superfamily
ADFLV_1993	COG0475	glutathione-regulated potassium exporter activity
ADFLV_1993	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ADFLV_1995	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ADFLV_1996	COG2169	Transcriptional regulator
ADFLV_1996	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ADFLV_2014	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ADFLV_2015	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ADFLV_2016	COG2258	MOSC domain
ADFLV_2020	COG0513	Belongs to the DEAD box helicase family
ADFLV_2026	COG1944	ATP diphosphatase activity
ADFLV_2029	COG0840	transmembrane signaling receptor activity
ADFLV_2030	COG0328	RNA-DNA hybrid ribonuclease activity
ADFLV_2031	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ADFLV_2036	COG0446	pyridine nucleotide-disulphide oxidoreductase
ADFLV_2042	COG0745	RESPONSE REGULATOR receiver
ADFLV_2052	COG5001	Diguanylate cyclase
ADFLV_2052	COG5002	protein histidine kinase activity
ADFLV_2055	COG0259	pyridoxamine-phosphate oxidase activity
ADFLV_2057	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ADFLV_2059	COG0513	Belongs to the DEAD box helicase family
ADFLV_2062	COG3287	FIST C domain
ADFLV_2062	COG2199	diguanylate cyclase activity
ADFLV_2062	COG2200	EAL domain
ADFLV_2064	COG1984	allophanate hydrolase subunit 2
ADFLV_2066	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
ADFLV_2070	COG0842	Transport permease protein
ADFLV_2071	COG0842	Transport permease protein
ADFLV_2071	COG1129	ABC transporter
ADFLV_2072	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ADFLV_2073	COG1309	transcriptional regulator
ADFLV_2074	COG0306	phosphate transporter
ADFLV_2076	COG0326	Molecular chaperone. Has ATPase activity
ADFLV_2077	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ADFLV_2082	COG2995	paraquat-inducible protein a
ADFLV_2085	COG5001	Diguanylate cyclase
ADFLV_2085	COG5002	protein histidine kinase activity
ADFLV_2089	COG2902	Dehydrogenase
ADFLV_2091	COG4335	DNA alkylation repair
ADFLV_2098	COG0010	Belongs to the arginase family
ADFLV_2099	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ADFLV_2100	COG2207	Transcriptional regulator
ADFLV_2104	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ADFLV_2105	COG1227	inorganic diphosphatase activity
ADFLV_2108	COG1027	Aspartate ammonia-lyase
ADFLV_2109	COG0745	RESPONSE REGULATOR receiver
ADFLV_2111	COG1115	amino acid carrier protein
ADFLV_2112	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ADFLV_2113	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ADFLV_2114	COG1047	Peptidyl-prolyl cis-trans
ADFLV_2117	COG2193	ferroxidase activity
ADFLV_2118	COG0823	Involved in the tonB-independent uptake of proteins
ADFLV_2120	COG0848	biopolymer transport protein
ADFLV_2121	COG0811	peptide transport
ADFLV_2122	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ADFLV_2123	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ADFLV_2124	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ADFLV_2125	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ADFLV_2126	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ADFLV_2127	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ADFLV_2129	COG1475	DNA binding
ADFLV_2130	COG1192	Involved in chromosome partitioning
ADFLV_2131	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
ADFLV_2131	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
ADFLV_2133	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ADFLV_2134	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ADFLV_2135	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ADFLV_2136	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ADFLV_2137	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ADFLV_2139	COG0358	DNA primase activity
ADFLV_2141	COG0571	ribonuclease III activity
ADFLV_2142	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ADFLV_2144	COG0501	Belongs to the peptidase M48B family
ADFLV_2148	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ADFLV_2150	COG0706	membrane insertase activity
ADFLV_2151	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ADFLV_2152	COG0230	Belongs to the bacterial ribosomal protein bL34 family
ADFLV_2153	COG0542	response to heat
ADFLV_2156	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ADFLV_2159	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ADFLV_2163	COG1120	ATPase activity
ADFLV_2170	COG0811	peptide transport
ADFLV_2171	COG0848	biopolymer transport protein
ADFLV_2174	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ADFLV_2175	COG3437	response regulator, receiver
ADFLV_2177	COG0784	Response regulator, receiver
ADFLV_2177	COG2205	protein histidine kinase activity
ADFLV_2178	COG0179	Fumarylacetoacetate (FAA) hydrolase
ADFLV_2184	COG0138	bifunctional purine biosynthesis protein purh
ADFLV_2185	COG0004	ammonium transporteR
ADFLV_2186	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ADFLV_2188	COG0741	lytic transglycosylase activity
ADFLV_2188	COG1196	nuclear chromosome segregation
ADFLV_2188	COG0739	heme binding
ADFLV_2191	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ADFLV_2194	COG0302	gtp cyclohydrolase
ADFLV_2195	COG0598	Magnesium transport protein CorA
ADFLV_2196	COG1459	type II secretion system
ADFLV_2200	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ADFLV_2201	COG0606	chelatase, subunit chli
ADFLV_2203	COG0242	peptide deformylase activity
ADFLV_2204	COG0740	serine-type endopeptidase activity
ADFLV_2205	COG0544	peptidyl-prolyl cis-trans isomerase activity
ADFLV_2210	COG1773	rubredoxin
ADFLV_2213	COG4974	Belongs to the 'phage' integrase family
ADFLV_2249	COG3501	Rhs element vgr protein
ADFLV_2263	COG0739	heme binding
ADFLV_2266	COG3501	Rhs element vgr protein
ADFLV_2271	COG3842	ATPase activity
ADFLV_2274	COG1177	transmembrane transport
ADFLV_2275	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ADFLV_2279	COG0626	cystathionine gamma-synthase activity
ADFLV_2282	COG0840	transmembrane signaling receptor activity
ADFLV_2284	COG5002	protein histidine kinase activity
ADFLV_2285	COG0840	transmembrane signaling receptor activity
ADFLV_2286	COG0840	transmembrane signaling receptor activity
ADFLV_2288	COG0583	DNA-binding transcription factor activity
ADFLV_2293	COG0745	RESPONSE REGULATOR receiver
ADFLV_2294	COG0456	acetyltransferase
ADFLV_2295	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
ADFLV_2298	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ADFLV_2300	COG2207	Transcriptional regulator
ADFLV_2301	COG0720	synthase
ADFLV_2302	COG0418	dihydroorotase activity
ADFLV_2304	COG1301	dicarboxylic acid transport
ADFLV_2305	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ADFLV_2308	COG1309	transcriptional regulator
ADFLV_2309	COG0840	transmembrane signaling receptor activity
ADFLV_2310	COG1028	Short-chain dehydrogenase reductase Sdr
ADFLV_2312	COG1858	cytochrome C peroxidase
ADFLV_2318	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ADFLV_2320	COG0668	transmembrane transport
ADFLV_2325	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ADFLV_2328	COG0348	domain, Protein
ADFLV_2329	COG4191	Histidine kinase
ADFLV_2330	COG2207	Transcriptional regulator
ADFLV_2330	COG4753	response regulator
ADFLV_2332	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ADFLV_2333	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ADFLV_2338	COG0716	FMN binding
ADFLV_2341	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
ADFLV_2344	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
ADFLV_2345	COG0159	tryptophan synthase activity
ADFLV_2346	COG0038	chloride channel
ADFLV_2348	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ADFLV_2349	COG2255	four-way junction helicase activity
ADFLV_2350	COG0628	permease
ADFLV_2352	COG4628	conserved protein (DUF2132)
ADFLV_2363	COG0731	radical SAM domain protein
ADFLV_2364	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ADFLV_2366	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ADFLV_2369	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ADFLV_2371	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ADFLV_2373	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ADFLV_2374	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ADFLV_2375	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
ADFLV_2375	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ADFLV_2376	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
ADFLV_2377	COG2990	Protein conserved in bacteria
ADFLV_2382	COG1696	Membrane protein involved in D-alanine export
ADFLV_2389	COG0438	transferase activity, transferring glycosyl groups
ADFLV_2390	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ADFLV_2394	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ADFLV_2396	COG0493	'glutamate synthase
ADFLV_2397	COG0069	glutamate synthase activity
ADFLV_2397	COG0067	glutamate synthase
ADFLV_2397	COG0070	glutamate synthase
ADFLV_2399	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ADFLV_2400	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ADFLV_2403	COG0745	RESPONSE REGULATOR receiver
ADFLV_2417	COG0284	orotidine-5'-phosphate decarboxylase activity
ADFLV_2418	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ADFLV_2419	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ADFLV_2420	COG3706	GGDEF domain
ADFLV_2421	COG2877	3-deoxy-8-phosphooctulonate synthase activity
ADFLV_2426	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ADFLV_2435	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ADFLV_2447	COG1739	Uncharacterized protein family UPF0029
ADFLV_2449	COG0196	riboflavin kinase activity
ADFLV_2450	COG2226	methyltransferase
ADFLV_2451	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ADFLV_2453	COG0277	FAD linked oxidase domain protein
ADFLV_2455	COG2203	Gaf domain
ADFLV_2455	COG3706	GGDEF domain
ADFLV_2455	COG5001	Diguanylate cyclase
ADFLV_2455	COG4251	negative regulation of phosphorylation
ADFLV_2463	COG0542	response to heat
ADFLV_2464	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
ADFLV_2465	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ADFLV_2468	COG2030	dehydratase
ADFLV_2473	COG1970	mechanosensitive ion channel activity
ADFLV_2474	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ADFLV_2480	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ADFLV_2481	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ADFLV_2482	COG1157	protein secretion by the type III secretion system
ADFLV_2484	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ADFLV_2488	COG1677	Flagellar hook-basal body complex protein FliE
ADFLV_2490	COG0455	bacterial-type flagellum organization
ADFLV_2491	COG1419	protein localization to endoplasmic reticulum
ADFLV_2497	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ADFLV_2501	COG1749	Flagellar hook protein flgE
ADFLV_2502	COG1749	Flagellar hook protein flgE
ADFLV_2504	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ADFLV_2506	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ADFLV_2507	COG1766	The M ring may be actively involved in energy transduction
ADFLV_2508	COG1815	bacterial-type flagellum-dependent cell motility
ADFLV_2509	COG4786	Flagellar basal body rod
ADFLV_2511	COG0745	RESPONSE REGULATOR receiver
ADFLV_2515	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ADFLV_2517	COG0228	four-way junction DNA binding
ADFLV_2518	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ADFLV_2519	COG0564	pseudouridine synthase activity
ADFLV_2520	COG1519	Transferase
ADFLV_2522	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ADFLV_2523	COG0752	glycyl-tRNA synthetase alpha subunit
ADFLV_2525	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ADFLV_2528	COG0840	transmembrane signaling receptor activity
ADFLV_2528	COG0840	transmembrane signaling receptor activity
ADFLV_2529	COG0497	DNA recombination
ADFLV_2530	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ADFLV_2531	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ADFLV_2532	COG0049	tRNA binding
ADFLV_2533	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ADFLV_2534	COG2814	Major facilitator Superfamily
ADFLV_2536	COG0840	transmembrane signaling receptor activity
ADFLV_2541	COG0310	cobalt ion transport
ADFLV_2545	COG1605	Chorismate mutase
ADFLV_2545	COG0077	Prephenate dehydratase
ADFLV_2552	COG4569	acetaldehyde dehydrogenase (acetylating) activity
ADFLV_2557	COG0633	Ferredoxin
ADFLV_2557	COG0543	2 iron, 2 sulfur cluster binding
ADFLV_2558	COG0039	L-malate dehydrogenase activity
ADFLV_2560	COG0784	Response regulator, receiver
ADFLV_2563	COG0730	response to heat
ADFLV_2571	COG0745	RESPONSE REGULATOR receiver
ADFLV_2572	COG0840	transmembrane signaling receptor activity
ADFLV_2573	COG1028	Short-chain dehydrogenase reductase Sdr
ADFLV_2574	COG0473	3-isopropylmalate dehydrogenase activity
ADFLV_2577	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ADFLV_2578	COG0085	RNA polymerase activity
ADFLV_2579	COG0222	ribosome binding
ADFLV_2580	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ADFLV_2581	COG0081	regulation of translation
ADFLV_2582	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ADFLV_2583	COG0250	Participates in transcription elongation, termination and antitermination
ADFLV_2586	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ADFLV_2587	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ADFLV_2592	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ADFLV_2593	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ADFLV_2594	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ADFLV_2595	COG0444	Belongs to the ABC transporter superfamily
ADFLV_2596	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
ADFLV_2597	COG0174	glutamine synthetase
ADFLV_2600	COG0314	molybdopterin synthase activity
ADFLV_2602	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
ADFLV_2603	COG1968	undecaprenyl-diphosphatase activity
ADFLV_2605	COG0772	Belongs to the SEDS family
ADFLV_2607	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ADFLV_2615	COG0512	Glutamine amidotransferase of anthranilate synthase
ADFLV_2616	COG1840	ABC-type Fe3 transport system, periplasmic component
ADFLV_2617	COG1178	ABC-type Fe3 transport system permease component
ADFLV_2618	COG3842	ATPase activity
ADFLV_2626	COG2183	response to ionizing radiation
ADFLV_2629	COG0251	oxidation-reduction process
ADFLV_2632	COG2095	MarC family integral membrane protein
ADFLV_2633	COG0765	amino acid transport
ADFLV_2638	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ADFLV_2642	COG0335	large ribosomal subunit rRNA binding
ADFLV_2643	COG0336	Belongs to the RNA methyltransferase TrmD family
ADFLV_2645	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ADFLV_2646	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ADFLV_2647	COG0356	it plays a direct role in the translocation of protons across the membrane
ADFLV_2649	COG1074	ATP-dependent DNA helicase activity
ADFLV_2650	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ADFLV_2651	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ADFLV_2652	COG0723	plastoquinol--plastocyanin reductase activity
ADFLV_2653	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ADFLV_2656	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ADFLV_2658	COG0303	'Molybdopterin
ADFLV_2659	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ADFLV_2661	COG0602	queuosine metabolic process
ADFLV_2663	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ADFLV_2664	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ADFLV_2665	COG0825	malonyl-CoA metabolic process
ADFLV_2666	COG0537	adenosine 5'-monophosphoramidase activity
ADFLV_2667	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ADFLV_2668	COG0072	phenylalanine-tRNA ligase activity
ADFLV_2668	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ADFLV_2669	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ADFLV_2670	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ADFLV_2671	COG1185	polyribonucleotide nucleotidyltransferase activity
ADFLV_2671	COG0539	negative regulation of cytoplasmic translation
ADFLV_2672	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ADFLV_2673	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ADFLV_2674	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ADFLV_2674	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ADFLV_2675	COG0779	Required for maturation of 30S ribosomal subunits
ADFLV_2676	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ADFLV_2677	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ADFLV_2679	COG0083	homoserine kinase activity
ADFLV_2681	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
ADFLV_2684	COG0157	Belongs to the NadC ModD family
ADFLV_2686	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ADFLV_2688	COG4773	Receptor
ADFLV_2690	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ADFLV_2694	COG1538	Outer membrane efflux protein
ADFLV_2695	COG1846	Transcriptional regulator
ADFLV_2703	COG3278	Belongs to the heme-copper respiratory oxidase family
ADFLV_2704	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ADFLV_2705	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ADFLV_2706	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ADFLV_2707	COG0210	DNA helicase
ADFLV_2709	COG1242	4 iron, 4 sulfur cluster binding
ADFLV_2710	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ADFLV_2711	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ADFLV_2712	COG0492	ferredoxin-NADP+ reductase activity
ADFLV_2713	COG3118	belongs to the thioredoxin family
ADFLV_2714	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ADFLV_2719	COG0791	NLP P60 protein
ADFLV_2720	COG0791	NLP P60 protein
ADFLV_2723	COG0697	spore germination
ADFLV_2725	COG0424	maF-like protein
ADFLV_2727	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ADFLV_2728	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ADFLV_2729	COG1605	Chorismate mutase
ADFLV_2729	COG0077	Prephenate dehydratase
ADFLV_2730	COG0019	diaminopimelate decarboxylase activity
ADFLV_2731	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ADFLV_2732	COG0149	triose-phosphate isomerase activity
ADFLV_2733	COG0126	phosphoglycerate kinase activity
ADFLV_2735	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ADFLV_2737	COG0018	arginyl-trna synthetase
ADFLV_2739	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ADFLV_2740	COG0204	Acyl-transferase
ADFLV_2742	COG0047	phosphoribosylformylglycinamidine synthase activity
ADFLV_2743	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ADFLV_2744	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ADFLV_2745	COG0793	Belongs to the peptidase S41A family
ADFLV_2748	COG0585	pseudouridine synthase activity
ADFLV_2754	COG4191	Histidine kinase
ADFLV_2764	COG4974	Belongs to the 'phage' integrase family
ADFLV_2767	COG0129	dihydroxy-acid dehydratase activity
ADFLV_2768	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ADFLV_2769	COG0745	RESPONSE REGULATOR receiver
ADFLV_2770	COG0642	Histidine kinase
ADFLV_2773	COG0702	epimerase
ADFLV_2774	COG1492	cobalamin metabolic process
ADFLV_2778	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ADFLV_2779	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
ADFLV_2781	COG2095	MarC family integral membrane protein
ADFLV_2782	COG1083	cytidylyl-transferase
ADFLV_2782	COG2755	lipolytic protein G-D-S-L family
ADFLV_2783	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
ADFLV_2786	COG4232	protein-disulfide reductase activity
ADFLV_2787	COG3118	belongs to the thioredoxin family
ADFLV_2789	COG0189	ligase activity
ADFLV_2792	COG2200	EAL domain
ADFLV_2792	COG2199	diguanylate cyclase activity
ADFLV_2792	COG3287	FIST C domain
ADFLV_2793	COG0688	phosphatidylethanolamine metabolic process
ADFLV_2795	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
ADFLV_2797	COG0443	Heat shock 70 kDa protein
ADFLV_2798	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ADFLV_2799	COG1420	regulation of RNA biosynthetic process
ADFLV_2800	COG2358	TRAP transporter, solute receptor (TAXI family
ADFLV_2802	COG2197	response regulator
ADFLV_2804	COG0101	tRNA pseudouridine synthase activity
ADFLV_2806	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ADFLV_2807	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ADFLV_2808	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ADFLV_2809	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ADFLV_2811	COG4581	dead DEAH box helicase
ADFLV_2812	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ADFLV_2816	COG3980	spore coat polysaccharide biosynthesis protein
ADFLV_2817	COG2089	acid synthase
ADFLV_2818	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ADFLV_2820	COG1028	Short-chain dehydrogenase reductase Sdr
ADFLV_2827	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ADFLV_2833	COG1083	cytidylyl-transferase
ADFLV_2835	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ADFLV_2836	COG1086	Polysaccharide biosynthesis protein
ADFLV_2838	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ADFLV_2839	COG0148	phosphopyruvate hydratase activity
ADFLV_2842	COG0475	glutathione-regulated potassium exporter activity
ADFLV_2842	COG0569	domain protein
ADFLV_2843	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ADFLV_2847	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
ADFLV_2849	COG1007	ATP synthesis coupled electron transport
ADFLV_2851	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ADFLV_2852	COG0713	ATP synthesis coupled electron transport
ADFLV_2853	COG0839	Belongs to the complex I subunit 6 family
ADFLV_2854	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ADFLV_2855	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ADFLV_2856	COG1034	ATP synthesis coupled electron transport
ADFLV_2859	COG0649	NAD binding
ADFLV_2861	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ADFLV_2862	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ADFLV_2863	COG1222	aaa ATPase
ADFLV_2869	COG0659	secondary active sulfate transmembrane transporter activity
ADFLV_2871	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
ADFLV_2872	COG1252	NADH dehydrogenase
ADFLV_2873	COG0733	neurotransmitter:sodium symporter activity
ADFLV_2875	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ADFLV_2877	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ADFLV_2878	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ADFLV_2879	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ADFLV_2883	COG0445	tRNA wobble uridine modification
ADFLV_2886	COG0348	domain, Protein
ADFLV_2887	COG0504	CTP synthase activity
ADFLV_2888	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ADFLV_2888	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
ADFLV_2891	COG0693	protein deglycase activity
ADFLV_2894	COG0587	DNA-directed DNA polymerase activity
ADFLV_2895	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
ADFLV_2898	COG0315	cyclic pyranopterin monophosphate synthase activity
ADFLV_2899	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ADFLV_2905	COG0670	Belongs to the BI1 family
ADFLV_2906	COG0352	thiamine-phosphate diphosphorylase activity
ADFLV_2908	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ADFLV_2910	COG0233	cytoplasmic translational termination
ADFLV_2911	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ADFLV_2913	COG2814	Major facilitator Superfamily
ADFLV_2914	COG1196	nuclear chromosome segregation
ADFLV_2914	COG3264	Mechanosensitive ion channel
ADFLV_2916	COG3022	response to hydroperoxide
ADFLV_2917	COG3012	SEC-C Motif Domain Protein
ADFLV_2921	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ADFLV_2923	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ADFLV_2926	COG1704	LemA family
ADFLV_2929	COG0546	phosphoglycolate phosphatase activity
ADFLV_2933	COG2814	Major facilitator Superfamily
ADFLV_2935	COG4191	Histidine kinase
ADFLV_2940	COG3706	GGDEF domain
ADFLV_2942	COG0840	transmembrane signaling receptor activity
ADFLV_2943	COG0784	Response regulator, receiver
ADFLV_2943	COG3437	response regulator, receiver
ADFLV_2948	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ADFLV_2954	COG2081	HI0933 family
ADFLV_2960	COG1959	2 iron, 2 sulfur cluster binding
ADFLV_2963	COG0175	sulfate reduction
ADFLV_2964	COG0175	sulfate reduction
ADFLV_2965	COG2895	sulfate adenylyltransferase (ATP) activity
ADFLV_2967	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ADFLV_2968	COG1408	metallophosphoesterase
ADFLV_2969	COG0071	Belongs to the small heat shock protein (HSP20) family
ADFLV_2973	COG0840	transmembrane signaling receptor activity
ADFLV_2975	COG4208	sulfate ABC transporter
ADFLV_2976	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
ADFLV_2977	COG3287	FIST C domain
ADFLV_2977	COG2200	EAL domain
ADFLV_2977	COG2199	diguanylate cyclase activity
ADFLV_2978	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
ADFLV_2979	COG1959	2 iron, 2 sulfur cluster binding
ADFLV_2983	COG2308	Evidence 4 Homologs of previously reported genes of
ADFLV_2987	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ADFLV_2988	COG1858	cytochrome C peroxidase
ADFLV_2993	COG0745	RESPONSE REGULATOR receiver
ADFLV_2994	COG0642	Histidine kinase
ADFLV_2995	COG2226	methyltransferase
ADFLV_2997	COG0784	Response regulator, receiver
ADFLV_2997	COG3437	response regulator, receiver
ADFLV_2998	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
ADFLV_2999	COG2066	Belongs to the glutaminase family
ADFLV_3000	COG2860	membrane
ADFLV_3002	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ADFLV_3003	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ADFLV_3004	COG0594	ribonuclease P activity
ADFLV_3005	COG0257	Belongs to the bacterial ribosomal protein bL36 family