locus-tag	class	description
ALANTH_0001	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
ALANTH_0002	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
ALANTH_0003	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
ALANTH_0004	ENOG4105H3G	oxidoreductase
ALANTH_0005	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
ALANTH_0010	ENOG4108BSC	Methyltransferase
ALANTH_0011	ENOG4105E0A	ABC, transporter
ALANTH_0012	ENOG4105EHG	Permease protein
ALANTH_0016	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
ALANTH_0017	ENOG4105E0C	molybdate abc transporter
ALANTH_0019	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
ALANTH_0020	ENOG4105F4R	Transcriptional regulator mode
ALANTH_0025	ENOG4105EI2	Pseudouridine synthase
ALANTH_0026	ENOG4107QTF	adenylosuccinate lyase
ALANTH_0027	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
ALANTH_0028	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
ALANTH_0032	ENOG4105KVH	Transcriptional regulator
ALANTH_0033	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
ALANTH_0034	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
ALANTH_0037	ENOG4105DAA	L-lactate
ALANTH_0039	ENOG4105BZU	Histidine kinase
ALANTH_0040	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
ALANTH_0041	ENOG4107QR9	Iron-sulfur cluster binding protein
ALANTH_0042	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
ALANTH_0043	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
ALANTH_0044	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
ALANTH_0045	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
ALANTH_0046	ENOG4105C1J	atp-dependent rna helicase
ALANTH_0047	ENOG4105CJ3	phosphate transporter
ALANTH_0049	ENOG4105CAQ	asparagine synthetase
ALANTH_0051	ENOG4108IAB	Phoh family
ALANTH_0052	ENOG4108YXA	Membrane
ALANTH_0053	ENOG4105D1H	recombination factor protein RarA
ALANTH_0054	ENOG4105FE9	pseudouridine synthase
ALANTH_0055	ENOG4105C2X	Arabinose 5-phosphate isomerase
ALANTH_0056	ENOG4105CN5	Metallo-Beta-Lactamase
ALANTH_0057	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
ALANTH_0058	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
ALANTH_0061	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
ALANTH_0062	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
ALANTH_0063	ENOG4105VFU	Rna-binding protein
ALANTH_0073	ENOG4105V75	Transcriptional regulator
ALANTH_0074	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
ALANTH_0075	ENOG4105D6E	homoserine dehydrogenase
ALANTH_0076	ENOG4105CHM	Aminotransferase
ALANTH_0080	ENOG41082DI	50s ribosomal protein l31
ALANTH_0081	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
ALANTH_0083	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
ALANTH_0085	ENOG4105DFP	Integrase
ALANTH_0095	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
ALANTH_0099	ENOG4105DVF	Cytosine-specific methyltransferase
ALANTH_0107	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
ALANTH_0110	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
ALANTH_0111	ENOG4105C0B	DNA polymerase III (alpha subunit)
ALANTH_0115	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
ALANTH_0116	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
ALANTH_0117	ENOG4105C58	cytochrome c oxidase accessory protein ccog
ALANTH_0119	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
ALANTH_0120	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
ALANTH_0121	ENOG4105BZU	Histidine kinase
ALANTH_0122	ENOG4105BZU	Histidine kinase
ALANTH_0123	ENOG4107SA8	fad-dependent pyridine nucleotide-disulfide oxidoreductase
ALANTH_0125	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
ALANTH_0126	ENOG4105C2I	pirin domain protein
ALANTH_0128	ENOG4108YYC	ycei family
ALANTH_0130	ENOG4108YYC	ycei family
ALANTH_0132	ENOG4107UUH	Aminotransferase
ALANTH_0133	ENOG4105CYE	ATP phosphoribosyltransferase regulatory subunit
ALANTH_0134	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
ALANTH_0136	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
ALANTH_0138	ENOG4108ZAI	phosphatidylglycerophosphatase a
ALANTH_0140	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
ALANTH_0142	ENOG41084QV	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
ALANTH_0143	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
ALANTH_0144	ENOG4105D1F	ATP-binding protein
ALANTH_0146	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
ALANTH_0149	ENOG4105CM2	brancheD-chain amino acid aminotransferase
ALANTH_0153	ENOG4105DZ1	carboxypeptidase
ALANTH_0156	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
ALANTH_0157	ENOG4108T3F	Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes
ALANTH_0160	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
ALANTH_0166	ENOG4105ETU	transcriptional activator (TenA
ALANTH_0167	ENOG4108UJD	30S ribosomal protein S9
ALANTH_0168	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
ALANTH_0169	ENOG4105BZU	Histidine kinase
ALANTH_0172	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
ALANTH_0173	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
ALANTH_0174	ENOG4105E2Z	phosphate ABC transporter (Permease
ALANTH_0175	ENOG4105C8U	phosphate abc transporter
ALANTH_0176	ENOG4108M8H	domain protein
ALANTH_0177	ENOG4105PWN	phosphate abc transporter
ALANTH_0182	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
ALANTH_0183	ENOG4108317	Binds directly to 16S ribosomal RNA (By similarity)
ALANTH_0184	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
ALANTH_0185	ENOG410813J	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
ALANTH_0186	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
ALANTH_0187	ENOG41080AZ	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
ALANTH_0188	ENOG4107SA8	fad-dependent pyridine nucleotide-disulfide oxidoreductase
ALANTH_0190	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
ALANTH_0191	ENOG41084M8	50s ribosomal protein L35
ALANTH_0192	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
ALANTH_0198	ENOG4105KNE	Phosphatidate cytidylyltransferase
ALANTH_0199	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
ALANTH_0202	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
ALANTH_0204	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
ALANTH_0205	ENOG4105VF7	tolerance protein
ALANTH_0206	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
ALANTH_0213	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
ALANTH_0216	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
ALANTH_0217	ENOG4105C8Q	Methyl-accepting chemotaxis
ALANTH_0219	ENOG4105CV1	Transketolase (EC 2.2.1.1)
ALANTH_0221	ENOG4107R5R	arsenical pump membrane protein
ALANTH_0222	ENOG4105CK2	sodium dicarboxylate symporter
ALANTH_0225	ENOG4108HPI	phosphatidate Cytidylyltransferase
ALANTH_0233	ENOG4108YZA	Nitrogen regulatory protein pii
ALANTH_0234	ENOG4105EKE	dihydroorotase
ALANTH_0235	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
ALANTH_0236	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
ALANTH_0238	ENOG4105VS8	Flagellar biosynthetic protein fliq
ALANTH_0241	ENOG4105X6C	Flagellar basal body-associated protein FliL
ALANTH_0245	ENOG4107TPX	flagellar hook-associated
ALANTH_0249	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
ALANTH_0251	ENOG4107R03	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
ALANTH_0253	ENOG410829W	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
ALANTH_0256	ENOG4105D6U	Sodium Glutamate Symporter
ALANTH_0257	ENOG4105GSH	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
ALANTH_0259	ENOG4105EAC	phosphoserine phosphatase
ALANTH_0260	ENOG4107V25	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
ALANTH_0261	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
ALANTH_0262	ENOG4105KUZ	arsenate reductase
ALANTH_0263	ENOG410855J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
ALANTH_0264	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
ALANTH_0267	ENOG4105DFU	Cell wall formation (By similarity)
ALANTH_0278	ENOG4105CVR	type I restriction-modification system
ALANTH_0285	ENOG4105ENA	helicase
ALANTH_0288	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
ALANTH_0289	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
ALANTH_0290	ENOG410821Z	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum (By similarity)
ALANTH_0291	ENOG4108VMB	DNA polymerase III subunit delta'
ALANTH_0292	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
ALANTH_0293	ENOG4108UUM	single-stranded DNA-binding protein
ALANTH_0294	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
ALANTH_0296	ENOG4105C8N	cysteinyl-tRNA synthetase
ALANTH_0297	ENOG4105CHV	Transcription elongation factor NusA
ALANTH_0299	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
ALANTH_0300	ENOG4105KB8	(LipO)protein
ALANTH_0302	ENOG4105DVY	radical SAM domain protein
ALANTH_0304	ENOG4107B2H	carbonic anhydrase
ALANTH_0305	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
ALANTH_0306	ENOG41082UM	UPF0102 protein
ALANTH_0313	ENOG4105C8Y	Acetylornithine aminotransferase
ALANTH_0315	ENOG4105CXT	aspartate transcarbamylase
ALANTH_0320	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
ALANTH_0322	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
ALANTH_0326	ENOG4105C5I	Dehydrogenase
ALANTH_0329	ENOG4105CR4	methylisocitrate lyase
ALANTH_0330	ENOG4105BZN	citrate synthase
ALANTH_0331	ENOG4108I0Z	Aconitate hydratase
ALANTH_0332	ENOG4105C7F	AcnD-accessory protein PrpF
ALANTH_0333	ENOG4105CHJ	isochorismatase hydrolase
ALANTH_0334	ENOG4108QD1	Membrane
ALANTH_0335	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
ALANTH_0337	ENOG4107QMP	dna polymerase iii subunits gamma and tau
ALANTH_0338	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
ALANTH_0340	ENOG4105D82	Glutamate dehydrogenase
ALANTH_0341	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
ALANTH_0342	ENOG4105D3R	alkyl hydroperoxide reductase
ALANTH_0344	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
ALANTH_0346	ENOG4105YQ2	50s ribosomal protein l32
ALANTH_0347	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
ALANTH_0348	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
ALANTH_0352	ENOG4105E33	succinate dehydrogenase
ALANTH_0353	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
ALANTH_0354	ENOG4108S24	Fumarate reduCtase
ALANTH_0355	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
ALANTH_0356	ENOG4105C8S	subunit m
ALANTH_0357	ENOG4105D65	subunit l
ALANTH_0358	ENOG41080EA	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
ALANTH_0359	ENOG4105DF2	NADH dehydrogenase subunit j
ALANTH_0361	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
ALANTH_0362	ENOG4108IEH	NADH dehydrogenase subunit g
ALANTH_0363	ENOG4105BZN	citrate synthase
ALANTH_0365	ENOG4105GKE	subunit e
ALANTH_0366	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
ALANTH_0367	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
ALANTH_0368	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
ALANTH_0369	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
ALANTH_0370	ENOG4107XM3	UPF0442 protein
ALANTH_0371	ENOG4105DWK	Membrane
ALANTH_0374	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
ALANTH_0376	ENOG4105C8Q	Methyl-accepting chemotaxis
ALANTH_0377	ENOG4108ZK4	sdia-regulated domain-containing protein
ALANTH_0380	ENOG4105E0K	tonB-dependent siderophore receptor
ALANTH_0382	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
ALANTH_0386	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
ALANTH_0389	ENOG4105BZ1	(ABC) transporter
ALANTH_0394	ENOG4105T16	Transcriptional regulator (AraC family)
ALANTH_0396	ENOG4105PGM	cation diffusion facilitator family transporter
ALANTH_0398	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
ALANTH_0400	ENOG4105BZU	Histidine kinase
ALANTH_0401	ENOG4105CRE	cytochrome C
ALANTH_0402	ENOG4105EAU	Plays a role in nitrite reduction (By similarity)
ALANTH_0403	ENOG4108W6G	cytochrome C
ALANTH_0404	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
ALANTH_0408	ENOG4108ZMS	Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity)
ALANTH_0409	ENOG4105GXZ	Ferredoxin-type protein NapH
ALANTH_0410	ENOG4108BGM	Quinol dehydrogenase periplasmic component
ALANTH_0411	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
ALANTH_0412	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
ALANTH_0413	ENOG4108RA0	tripartite ATP-independent periplasmic transporter, DctQ component
ALANTH_0414	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
ALANTH_0416	ENOG410812K	response regulator receiver protein
ALANTH_0419	ENOG4107QYG	anthranilate phosphoribosyltransferase
ALANTH_0420	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
ALANTH_0421	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
ALANTH_0423	ENOG4108KA0	Inherit from COG: Phosphoesterase, DHHA1
ALANTH_0424	ENOG4105K4P	CoA-binding domain protein
ALANTH_0425	ENOG4105DHQ	Histidine kinase
ALANTH_0426	ENOG4105ETX	regulatoR
ALANTH_0427	ENOG4105EIN	peptidylprolyl cis-trans isomerase
ALANTH_0428	ENOG4105D2N	Aldolase
ALANTH_0430	ENOG4109015	Biopolymer transport protein exbD tolR
ALANTH_0431	ENOG4105M8K	biopolymer transport protein
ALANTH_0432	ENOG4108D32	Methyltransferase
ALANTH_0435	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
ALANTH_0436	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
ALANTH_0438	ENOG4105EAH	synthase
ALANTH_0439	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
ALANTH_0440	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
ALANTH_0443	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
ALANTH_0444	ENOG4105VIE	preprotein translocase, subunit YajC
ALANTH_0445	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
ALANTH_0446	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
ALANTH_0449	ENOG4108SEK	ompa motb domain protein
ALANTH_0450	ENOG4105E14	MotA TolQ exbB proton channel
ALANTH_0452	ENOG4105C8T	Leucyl-tRNA synthetase
ALANTH_0454	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
ALANTH_0462	ENOG4108JA2	transcriptioN-repair coupling factor
ALANTH_0465	ENOG4105MA0	exported protein
ALANTH_0470	ENOG4105CBX	hi0933 family
ALANTH_0471	ENOG4105C8Q	Methyl-accepting chemotaxis
ALANTH_0474	ENOG4105BZU	Histidine kinase
ALANTH_0475	ENOG4105D48	metallophosphoesterase
ALANTH_0478	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
ALANTH_0479	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
ALANTH_0480	ENOG4108V3W	Chemotaxis protein, CheW
ALANTH_0482	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
ALANTH_0483	ENOG41084FT	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
ALANTH_0485	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
ALANTH_0486	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
ALANTH_0488	ENOG4105ECY	inositol monophosphatase
ALANTH_0489	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
ALANTH_0491	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
ALANTH_0492	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
ALANTH_0493	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
ALANTH_0495	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
ALANTH_0496	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
ALANTH_0497	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
ALANTH_0498	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
ALANTH_0501	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
ALANTH_0504	ENOG41081FY	multiple antibiotic resistance (MarC)-related
ALANTH_0506	ENOG4105BZU	Histidine kinase
ALANTH_0507	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
ALANTH_0508	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
ALANTH_0512	ENOG4107UIE	peptidase
ALANTH_0513	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
ALANTH_0516	ENOG4105CDV	Ompa motb domain protein
ALANTH_0517	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
ALANTH_0519	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
ALANTH_0520	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
ALANTH_0521	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ALANTH_0522	ENOG4105DC7	peptidase M24
ALANTH_0523	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
ALANTH_0524	ENOG4107SYB	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
ALANTH_0527	ENOG4108IJ2	phosphate acetyltransferase
ALANTH_0528	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
ALANTH_0530	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
ALANTH_0534	ENOG4107QN1	sodium solute
ALANTH_0536	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
ALANTH_0538	ENOG4107QN1	sodium solute
ALANTH_0540	ENOG4108STX	response regulator
ALANTH_0550	ENOG4105CEV	competence damage-inducible protein
ALANTH_0551	ENOG4107RSR	Malate quinone oxidoreductase
ALANTH_0552	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
ALANTH_0556	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
ALANTH_0557	ENOG4105CE9	30S ribosomal protein S2
ALANTH_0558	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
ALANTH_0561	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
ALANTH_0562	ENOG4105BZU	Histidine kinase
ALANTH_0563	ENOG4105C59	p-type ATPase
ALANTH_0566	ENOG4107H6U	ABC transporter
ALANTH_0567	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
ALANTH_0568	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
ALANTH_0569	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
ALANTH_0570	ENOG4107S90	membrAne
ALANTH_0572	ENOG4105FDK	ABC transporter
ALANTH_0574	ENOG4105QNR	S1 RNA binding domain protein
ALANTH_0575	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
ALANTH_0578	ENOG4105ENA	helicase
ALANTH_0580	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
ALANTH_0582	ENOG4108XRS	Monoheme cytochrome SoxX (Sulfur oxidation)
ALANTH_0585	ENOG41088H4	Diheme cytochrome SoxA (Sulfur oxidation)
ALANTH_0596	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
ALANTH_0607	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
ALANTH_0611	ENOG4107RDB	Major Facilitator
ALANTH_0612	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
ALANTH_0617	ENOG410901F	(LipO)protein
ALANTH_0618	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
ALANTH_0620	ENOG4105KJF	protein tyrosine phosphatase
ALANTH_0621	ENOG4107SDU	Methyl-accepting chemotaxis
ALANTH_0623	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
ALANTH_0624	ENOG4105C8Q	Methyl-accepting chemotaxis
ALANTH_0628	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
ALANTH_0630	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
ALANTH_0631	ENOG4105C9B	Cysteine desulfurase
ALANTH_0633	ENOG4105C3K	feS assembly ATPase SufC
ALANTH_0635	ENOG4107RIU	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins (By similarity)
ALANTH_0636	ENOG4105CJW	magnesium transporter
ALANTH_0637	ENOG4105BZU	Histidine kinase
ALANTH_0638	ENOG4105CH7	arginosuccinase
ALANTH_0640	ENOG4105CUZ	uba thif-type nad fad binding protein
ALANTH_0641	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
ALANTH_0643	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
ALANTH_0644	ENOG4105CSM	endonuclease III
ALANTH_0646	ENOG4105C8Q	Methyl-accepting chemotaxis
ALANTH_0649	ENOG4108YZG	isomerase
ALANTH_0650	ENOG4105C3F	Signal peptidase i
ALANTH_0651	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
ALANTH_0652	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
ALANTH_0653	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
ALANTH_0656	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
ALANTH_0658	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
ALANTH_0659	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
ALANTH_0660	ENOG410692R	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
ALANTH_0661	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
ALANTH_0670	ENOG41090R7	Ferric uptake
ALANTH_0671	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
ALANTH_0672	ENOG4105N80	Ferric uptake regulator, Fur family
ALANTH_0674	ENOG4105D7X	high-affinity nickel-transporter
ALANTH_0678	ENOG4105C28	cystathionine
ALANTH_0681	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
ALANTH_0682	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
ALANTH_0684	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
ALANTH_0686	ENOG4105M15	transport protein ExbD
ALANTH_0687	ENOG4105M8K	biopolymer transport protein
ALANTH_0690	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
ALANTH_0691	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
ALANTH_0694	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
ALANTH_0695	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
ALANTH_0696	ENOG4105VG0	50S ribosomal protein l34
ALANTH_0697	ENOG4108512	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
ALANTH_0698	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
ALANTH_0700	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
ALANTH_0705	ENOG4105BZE	flagellar hook protein, FlgE
ALANTH_0707	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
ALANTH_0708	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
ALANTH_0709	ENOG4105CRQ	synthase (Component I)
ALANTH_0711	ENOG4105CRK	lysyL-tRNA synthetase
ALANTH_0714	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
ALANTH_0715	ENOG4105CDU	Replicative dna helicase
ALANTH_0716	ENOG4108VAU	general secretion pathway protein G
ALANTH_0717	ENOG4105C9Q	fumarate hydratase class II
ALANTH_0720	ENOG4105CE1	Ferrous iron transport protein b
ALANTH_0721	ENOG4105XFK	Ferrous iron transport protein A
ALANTH_0728	ENOG4105D22	carbon starvation protein
ALANTH_0729	ENOG4105C3G	gtp-binding protein
ALANTH_0730	ENOG4108HU6	Metal dependent phosphohydrolase
ALANTH_0733	ENOG4105NBK	UPF0345 protein
ALANTH_0734	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
ALANTH_0735	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
ALANTH_0737	ENOG4105C8Q	Methyl-accepting chemotaxis
ALANTH_0738	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
ALANTH_0739	ENOG4105CPF	Cell wall formation (By similarity)
ALANTH_0741	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
ALANTH_0744	ENOG4107QMZ	Dehydrogenase
ALANTH_0745	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
ALANTH_0746	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
ALANTH_0747	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
ALANTH_0748	ENOG4105KZZ	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
ALANTH_0749	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ALANTH_0750	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
ALANTH_0751	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
ALANTH_0752	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
ALANTH_0753	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
ALANTH_0754	ENOG41084HJ	50s ribosomal protein l29
ALANTH_0755	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
ALANTH_0756	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
ALANTH_0757	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
ALANTH_0758	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ALANTH_0759	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
ALANTH_0760	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
ALANTH_0761	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
ALANTH_0762	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
ALANTH_0763	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
ALANTH_0764	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
ALANTH_0765	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
ALANTH_0766	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
ALANTH_0767	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
ALANTH_0768	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
ALANTH_0770	ENOG4105C9M	aspartyl-trna synthetase
ALANTH_0772	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
ALANTH_0773	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
ALANTH_0775	ENOG4107YTP	response regulator receiver protein
ALANTH_0777	ENOG4105C8Q	Methyl-accepting chemotaxis
ALANTH_0780	ENOG4105C87	Aminotransferase class I and II
ALANTH_0781	ENOG4107QW4	alcohol dehydrogenase
ALANTH_0782	ENOG4105C8Q	Methyl-accepting chemotaxis
ALANTH_0783	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
ALANTH_0784	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
ALANTH_0785	ENOG4105C8Q	Methyl-accepting chemotaxis
ALANTH_0786	ENOG4105C8Q	Methyl-accepting chemotaxis
ALANTH_0787	ENOG4105C8Q	Methyl-accepting chemotaxis
ALANTH_0788	ENOG4105BZU	Histidine kinase
ALANTH_0795	ENOG4105CGK	Exodeoxyribonuclease III
ALANTH_0799	ENOG4107QP8	phosphohexose isomerase
ALANTH_0800	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
ALANTH_0801	ENOG4107QKV	phosphomannomutase
ALANTH_0808	ENOG4106R49	Methyltransferase
ALANTH_0809	ENOG4105D05	Receptor
ALANTH_0810	ENOG4105D05	Receptor
ALANTH_0812	ENOG4105D00	flagellar biosynthetic protein flhB
ALANTH_0814	ENOG4105K89	arsenate reductase
ALANTH_0816	ENOG4107QUV	Domain protein
ALANTH_0818	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
ALANTH_0819	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
ALANTH_0820	ENOG4105CUC	YeeE YedE family protein
ALANTH_0822	ENOG4105DWV	Homoserine O-trans-acetylase
ALANTH_0824	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
ALANTH_0825	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
ALANTH_0829	ENOG4107QQG	Dehydrogenase
ALANTH_0830	ENOG4107R5Z	Oxidoreductase domain protein
ALANTH_0831	ENOG4105J5G	Transferase hexapeptide repeat containing protein
ALANTH_0832	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
ALANTH_0834	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
ALANTH_0836	ENOG4107WZ3	Transferase
ALANTH_0837	ENOG4108Z7G	MaoC domain protein dehydratase
ALANTH_0840	ENOG4105D2T	synthase
ALANTH_0841	ENOG4107SE4	UDP-N-acetylglucosamine 2-epimerase
ALANTH_0847	ENOG4108MY6	biosynthesis protein
ALANTH_0849	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
ALANTH_0850	ENOG4108REZ	Imidazole glycerol phosphate synthase
ALANTH_0851	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
ALANTH_0854	ENOG4105EXC	Acyl-transferase
ALANTH_0855	ENOG4108IAJ	Nad-dependent epimerase dehydratase
ALANTH_0858	ENOG4105ESV	Glycosyl transferase, family 4
ALANTH_0859	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
ALANTH_0860	ENOG4105C5E	polysaccharide biosynthesis protein
ALANTH_0863	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
ALANTH_0870	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
ALANTH_0871	ENOG4108IYU	L-aspartate oxidase
ALANTH_0874	ENOG4108VKG	metal-dependent hydrolase
ALANTH_0875	ENOG4105CHM	Aminotransferase
ALANTH_0876	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
ALANTH_0877	ENOG4105F8J	Adenylate Guanylate cyclase
ALANTH_0882	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
ALANTH_0883	ENOG4105DR4	Methyltransferase
ALANTH_0886	ENOG4105C94	Transporter
ALANTH_0888	ENOG4105E0K	tonB-dependent siderophore receptor
ALANTH_0897	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
ALANTH_0898	ENOG4108URH	decarboxylase
ALANTH_0901	ENOG410903C	(LipO)protein
ALANTH_0902	ENOG4105CDY	transcriptional regulatory protein
ALANTH_0906	ENOG4105BZU	Histidine kinase
ALANTH_0908	ENOG4107QIJ	Aconitate hydratase 2
ALANTH_0909	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
ALANTH_0910	ENOG4105M08	Membrane
ALANTH_0911	ENOG4108VPT	UPF0234 protein
ALANTH_0912	ENOG4107VIJ	nudix hydrolase
ALANTH_0914	ENOG4105HDD	phospholipase
ALANTH_0915	ENOG4105DJV	ribulose-phosphate 3-epimerase
ALANTH_0916	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
ALANTH_0917	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
ALANTH_0920	ENOG4105DQU	oxidoreductase, subunit beta
ALANTH_0921	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
ALANTH_0924	ENOG4105QTX	Pfam:UPF0153
ALANTH_0926	ENOG4105DK0	Indole-3-glycerol phosphate synthase
ALANTH_0928	ENOG4105VSH	4-oxalocrotonate tautomerase
ALANTH_0932	ENOG4105DR5	peptidase
ALANTH_0934	ENOG4105C5H	ABC transporter
ALANTH_0935	ENOG4107TS3	membrane protein, TerC
ALANTH_0936	ENOG4105KNI	merR family transcriptional Regulator
ALANTH_0937	ENOG4105DVC	DnaJ domain protein
ALANTH_0940	ENOG4107YTP	response regulator receiver protein
ALANTH_0943	ENOG4105E3S	small subunit
ALANTH_0944	ENOG4105DPX	Hydrogenase, large subunit
ALANTH_0947	ENOG4108P97	
ALANTH_0950	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
ALANTH_0951	ENOG4105WRB	Hydrogenase assembly chaperone hypC hupF
ALANTH_0952	ENOG4105CQS	hydrogenase expression formation protein HypD
ALANTH_0954	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
ALANTH_0955	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
ALANTH_0957	ENOG4105C45	hydrogenase expression formation protein (HypE)
ALANTH_0958	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
ALANTH_0960	ENOG4105CFT	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity)
ALANTH_0964	ENOG4107RH8	nuclease SbcCD subunit D
ALANTH_0965	ENOG4105EYH	Exonuclease
ALANTH_0973	ENOG410841J	DNA-binding protein Hu
ALANTH_0975	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
ALANTH_0980	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
ALANTH_0981	ENOG4105E9K	Isocitrate dehydrogenase
ALANTH_0985	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
ALANTH_0986	ENOG4105ZGC	lipoprotein carrier protein
ALANTH_0988	ENOG4105C8Q	Methyl-accepting chemotaxis
ALANTH_0989	ENOG4105C8Q	Methyl-accepting chemotaxis
ALANTH_0993	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
ALANTH_0996	ENOG4105BZ1	(ABC) transporter
ALANTH_0998	ENOG4108STX	response regulator
ALANTH_1001	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
ALANTH_1002	ENOG4105C8Q	Methyl-accepting chemotaxis
ALANTH_1003	ENOG4105DFA	alanine racemase domain protein
ALANTH_1009	ENOG4106H6R	UPF0380 protein
ALANTH_1024	ENOG4105DZR	Type I site-specific deoxyribonuclease
ALANTH_1034	ENOG4105DZP	Membrane-associated zinc metalloprotease
ALANTH_1035	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
ALANTH_1036	ENOG4105CAN	Short-chain dehydrogenase reductase Sdr
ALANTH_1037	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
ALANTH_1039	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
ALANTH_1040	ENOG4105BZ1	(ABC) transporter
ALANTH_1041	ENOG4105CJR	Integral membrane protein (MviN
ALANTH_1043	ENOG4105I3K	Ferric uptake regulator, Fur family
ALANTH_1044	ENOG41080V7	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
ALANTH_1045	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
ALANTH_1047	ENOG4105CA0	peroxidase
ALANTH_1048	ENOG4105BZU	Histidine kinase
ALANTH_1050	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
ALANTH_1053	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
ALANTH_1054	ENOG4106H78	methyltransferase
ALANTH_1055	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
ALANTH_1057	ENOG4105EGI	Transcriptional regulator
ALANTH_1059	ENOG4105T16	Transcriptional regulator (AraC family)
ALANTH_1060	ENOG4105E1F	short-chain dehydrogenase reductase
ALANTH_1063	ENOG4105DUM	transcriptional regulator, lysR family
ALANTH_1064	ENOG4105HMI	Membrane
ALANTH_1071	ENOG4105KVH	Transcriptional regulator
ALANTH_1073	ENOG4108RCM	Nitroreductase
ALANTH_1075	ENOG4105C5H	ABC transporter
ALANTH_1076	ENOG4108S4H	thioesterase Superfamily protein
ALANTH_1077	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
ALANTH_1078	ENOG4106032	Glutathionylspermidine synthase
ALANTH_1080	ENOG4108TZV	Membrane
ALANTH_1083	ENOG4105CDV	Ompa motb domain protein
ALANTH_1084	ENOG4108JJA	ABC, transporter
ALANTH_1087	ENOG41061ZR	Transcriptional regulator
ALANTH_1088	ENOG4105EYG	tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site (By similarity)
ALANTH_1089	ENOG410841J	DNA-binding protein Hu
ALANTH_1111	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
ALANTH_1122	ENOG4105BZU	Histidine kinase
ALANTH_1123	ENOG4105KK6	nuclease
ALANTH_1185	ENOG4107RH8	nuclease SbcCD subunit D
ALANTH_1188	ENOG4105E2X	shikimate dehydrogenase
ALANTH_1191	ENOG4105C6K	Malic enzyme
ALANTH_1192	ENOG4105CIY	formyltetrahydrofolate deformylase
ALANTH_1193	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
ALANTH_1198	ENOG4108STX	response regulator
ALANTH_1205	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
ALANTH_1206	ENOG4105I08	Pseudouridine synthase
ALANTH_1207	ENOG4107XGZ	Hydrolase
ALANTH_1211	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
ALANTH_1212	ENOG4108JJB	ABC transporter
ALANTH_1213	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
ALANTH_1215	ENOG4105CVJ	phosphoglycerate mutase
ALANTH_1218	ENOG4105D49	3-dehydroquinate synthase
ALANTH_1220	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
ALANTH_1221	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
ALANTH_1223	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
ALANTH_1226	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
ALANTH_1228	ENOG4108HYG	acetyltransferase
ALANTH_1232	ENOG4105CNM	Receptor
ALANTH_1236	ENOG4105KVH	Transcriptional regulator
ALANTH_1237	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
ALANTH_1238	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
ALANTH_1240	ENOG4105C98	muts2 protein
ALANTH_1241	ENOG4105C37	(CBS) domain
ALANTH_1243	ENOG4105DKW	ABC transporter
ALANTH_1246	ENOG4105D4P	Coproporphyrinogen iii oxidase
ALANTH_1247	ENOG4105DBV	ornithine carbamoyltransferase
ALANTH_1248	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
ALANTH_1251	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
ALANTH_1253	ENOG41090VV	Protein of unknown function (DUF2846)
ALANTH_1254	ENOG4105D52	delta-aminolevulinic acid dehydratase
ALANTH_1255	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
ALANTH_1256	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
ALANTH_1261	ENOG4107YD3	Thioesterase
ALANTH_1263	ENOG4105C2Y	STE24 endopeptidase EC 3.4.24.84
ALANTH_1264	ENOG4105CGY	Dna recombination protein
ALANTH_1266	ENOG4105CGZ	zinc metallopeptidase
ALANTH_1268	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
ALANTH_1270	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
ALANTH_1275	ENOG4105C9X	ppx gppa phosphatase
ALANTH_1277	ENOG4105C7K	acetolactate synthase
ALANTH_1278	ENOG4108ZP8	Acetolactate synthase small subunit
ALANTH_1279	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
ALANTH_1280	ENOG4105CNU	cell division protein FtsK
ALANTH_1283	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
ALANTH_1284	ENOG4105CHH	sulfate transporter
ALANTH_1288	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
ALANTH_1290	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
ALANTH_1291	ENOG4108VYJ	response regulator receiver protein
ALANTH_1292	ENOG4105CBS	Chea signal transduction histidine kinase
ALANTH_1293	ENOG4105BZU	Histidine kinase
ALANTH_1294	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
ALANTH_1295	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
ALANTH_1296	ENOG4105EU0	Major facilitator Superfamily
ALANTH_1297	ENOG4108EU4	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
ALANTH_1300	ENOG4105DGW	oligopeptidase A
ALANTH_1301	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
ALANTH_1302	ENOG4105CSA	Coproporphyrinogen iii oxidase
ALANTH_1303	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
ALANTH_1304	ENOG4105CFH	Aspartokinase
ALANTH_1307	ENOG4105EEI	dihydropteroate synthase
ALANTH_1310	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ALANTH_1311	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
ALANTH_1313	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
ALANTH_1318	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
ALANTH_1320	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
ALANTH_1324	ENOG4105PV1	biotin lipoyl attachment domaiN-containing protein
ALANTH_1325	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
ALANTH_1331	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
ALANTH_1333	ENOG4105C4K	Nad synthetase
ALANTH_1336	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
ALANTH_1338	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
ALANTH_1339	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
ALANTH_1345	ENOG4105DF6	Fe-S oxidoreductase
ALANTH_1346	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
ALANTH_1349	ENOG4105C8Q	Methyl-accepting chemotaxis
ALANTH_1350	ENOG4105CPC	Aldo Keto reductase
ALANTH_1356	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
ALANTH_1360	ENOG4105C5X	domain protein
ALANTH_1361	ENOG4105BZU	Histidine kinase
ALANTH_1362	ENOG4105BZU	Histidine kinase
ALANTH_1363	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
ALANTH_1369	ENOG4105EYG	tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site (By similarity)
ALANTH_1370	ENOG4105CRE	cytochrome C
ALANTH_1371	ENOG4105CIN	aminoacyl-histidine dipeptidase
ALANTH_1373	ENOG4105C8Q	Methyl-accepting chemotaxis
ALANTH_1374	ENOG4105C8Q	Methyl-accepting chemotaxis
ALANTH_1375	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
ALANTH_1376	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
ALANTH_1377	ENOG4108ZT0	50S ribosomal protein l17
ALANTH_1378	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
ALANTH_1379	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
ALANTH_1380	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
ALANTH_1381	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ALANTH_1382	ENOG41067V7	50S ribosomal protein L36
ALANTH_1385	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
ALANTH_1386	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
ALANTH_1387	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
ALANTH_1392	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
ALANTH_1398	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
ALANTH_1399	ENOG4105KMT	branched-chain amino acid
ALANTH_1400	ENOG4108UMN	azlc family
ALANTH_1402	ENOG4105CNI	cell division protein FtsW
ALANTH_1403	ENOG4105C34	Pseudouridine synthase
ALANTH_1405	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
ALANTH_1406	ENOG4105CAK	Cell division ATP-binding protein ftsE
ALANTH_1410	ENOG4105CJN	penicillin-binding protein
ALANTH_1411	ENOG4105CN7	Flagellar biosynthetic protein FliP
ALANTH_1412	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
ALANTH_1414	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
ALANTH_1418	ENOG4105E0X	reductase
ALANTH_1419	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
ALANTH_1420	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
ALANTH_1421	ENOG4105ECP	epimerase
ALANTH_1422	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
ALANTH_1424	ENOG4105C2M	dna polymerase I
ALANTH_1425	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
ALANTH_1426	ENOG4108IUZ	ABC transporter
ALANTH_1427	ENOG4105K8N	protein family UPF0079, ATPase
ALANTH_1428	ENOG4107QYG	anthranilate phosphoribosyltransferase
ALANTH_1431	ENOG4105CDH	Citrulline--aspartate ligase
ALANTH_1432	ENOG4108IQD	Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Catalyzes an ATP-dependent two-step reaction where it forms a high energy D-alanyl AMP intermediate and transfers the alanyl residues from AMP to Dcp (By similarity)
ALANTH_1433	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
ALANTH_1436	ENOG4105X96	Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Activated D-alanyl-Dcp donates its D-alanyl substituent to membrane-associated LTA (By similarity)
ALANTH_1444	ENOG4105DWF	phosphomethylpyrimidine kinase
ALANTH_1445	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
ALANTH_1448	ENOG4105C58	cytochrome c oxidase accessory protein ccog
ALANTH_1450	ENOG4107VQW	regulatoR
ALANTH_1451	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
ALANTH_1456	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
ALANTH_1459	ENOG4105CE1	Ferrous iron transport protein b
ALANTH_1461	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
ALANTH_1462	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
ALANTH_1463	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
ALANTH_1464	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
ALANTH_1465	ENOG4105F4G	Membrane
ALANTH_1469	ENOG4105DSF	transport protein
ALANTH_1470	ENOG4105C37	(CBS) domain
ALANTH_1473	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
ALANTH_1474	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
ALANTH_1479	ENOG4105DKK	Benzoate
ALANTH_1480	ENOG4105DDY	UPF0142 protein ycaO
ALANTH_1482	ENOG4108RPX	mosc domain containing protein
ALANTH_1484	ENOG4105C5H	ABC transporter
ALANTH_1486	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
ALANTH_1487	ENOG4105C25	Primosomal protein n'
ALANTH_1492	ENOG4105CBX	hi0933 family
ALANTH_1494	ENOG4105CKW	Inner membrane protein yedI
ALANTH_1497	ENOG4105VCH	membrane
ALANTH_1500	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
ALANTH_1505	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
ALANTH_1508	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
ALANTH_1509	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
ALANTH_1510	ENOG4105K6T	rare lipoprotein A
ALANTH_1512	ENOG4105F8V	Hydrolase, tatD family
ALANTH_1514	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
ALANTH_1515	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
ALANTH_1516	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
ALANTH_1518	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
ALANTH_1519	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
ALANTH_1520	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
ALANTH_1521	ENOG4105CUT	histidyl-tRNA synthetase
ALANTH_1522	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
ALANTH_1523	ENOG4105D7W	serine acetyltransferase
ALANTH_1525	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
ALANTH_1526	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
ALANTH_1528	ENOG4105BZU	Histidine kinase
ALANTH_1529	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
ALANTH_1531	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
ALANTH_1532	ENOG4107QSN	dihydrolipoamide acetyltransferase
ALANTH_1533	ENOG4107QN2	dihydrolipoyl dehydrogenase
ALANTH_1539	ENOG4105NQN	cytochrome C
ALANTH_1540	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
ALANTH_1547	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
ALANTH_1549	ENOG4105C59	p-type ATPase
ALANTH_1550	ENOG4107YCR	Transcriptional regulator, ARSR family
ALANTH_1553	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
ALANTH_1554	ENOG4105DF3	Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds (By similarity)
ALANTH_1560	ENOG4107S7U	Sulfide dehydrogenase
ALANTH_1561	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
ALANTH_1563	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
ALANTH_1565	ENOG4105QAX	Iron-sulfur
ALANTH_1572	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
ALANTH_1574	ENOG4105E0K	tonB-dependent siderophore receptor
ALANTH_1578	ENOG4108KS2	transglutaminase domain protein
ALANTH_1580	ENOG4105QAX	Iron-sulfur
ALANTH_1582	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
ALANTH_1584	ENOG4105C1Y	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis (By similarity)
ALANTH_1585	ENOG4105EM7	Selenocysteine-specific translation elongation factor
ALANTH_1593	ENOG4105BZU	Histidine kinase
ALANTH_1596	ENOG4105DCI	Phosphohydrolase
ALANTH_1597	ENOG4105BZU	Histidine kinase
ALANTH_1598	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
ALANTH_1600	ENOG4105BZU	Histidine kinase
ALANTH_1601	ENOG4105C1J	atp-dependent rna helicase
ALANTH_1605	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
ALANTH_1610	ENOG4105EZV	Transcriptional regulator
ALANTH_1611	ENOG4107ZSV	Receptor
ALANTH_1612	ENOG4105JXB	ankyrin repeat-containing protein
ALANTH_1613	ENOG4105CH6	catalase
ALANTH_1614	ENOG4105DY2	Paraquat-inducible protein b
ALANTH_1615	ENOG4105F1S	paraquat-inducible protein a
ALANTH_1621	ENOG4108Z66	YbaK ebsC protein
ALANTH_1623	ENOG4105F1N	DNA alkylation repair
ALANTH_1626	ENOG4105PWN	phosphate abc transporter
ALANTH_1627	ENOG4105C8U	phosphate abc transporter
ALANTH_1628	ENOG4105E2Z	phosphate ABC transporter (Permease
ALANTH_1629	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
ALANTH_1630	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
ALANTH_1631	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
ALANTH_1632	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
ALANTH_1636	ENOG4105VEQ	Cold shock protein
ALANTH_1637	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
ALANTH_1638	ENOG4105CNM	Receptor
ALANTH_1642	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
ALANTH_1646	ENOG4105EMN	RNA polymerase sigma factor
ALANTH_1647	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
ALANTH_1648	ENOG4105CF7	AraC family transcriptional regulator
ALANTH_1649	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
ALANTH_1650	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
ALANTH_1651	ENOG4105CUY	Mechanosensitive ion channel
ALANTH_1652	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
ALANTH_1655	ENOG4108IJ0	Aspartate ammonia-lyase
ALANTH_1656	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
ALANTH_1657	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
ALANTH_1658	ENOG4108YZY	peptidylprolyl cis-trans isomerase
ALANTH_1661	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
ALANTH_1663	ENOG4105M8F	Biopolymer transport protein exbD tolR
ALANTH_1664	ENOG4105E02	MotA TolQ exbB proton channel
ALANTH_1665	ENOG41082MC	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
ALANTH_1666	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
ALANTH_1667	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
ALANTH_1668	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
ALANTH_1669	ENOG4105PQH	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
ALANTH_1670	ENOG4105YF2	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
ALANTH_1672	ENOG4105FA0	parb-like partition protein
ALANTH_1673	ENOG4107QJE	Chromosome Partitioning Protein
ALANTH_1675	ENOG41084IH	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
ALANTH_1683	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
ALANTH_1684	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
ALANTH_1685	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ALANTH_1686	ENOG4105K46	50S ribosomal protein l27
ALANTH_1687	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
ALANTH_1688	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
ALANTH_1690	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
ALANTH_1691	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
ALANTH_1692	ENOG4105CSR	polyphosphate kinase 2
ALANTH_1695	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
ALANTH_1697	ENOG4105E0X	reductase
ALANTH_1702	ENOG4105DC1	bifunctional purine biosynthesis protein purh
ALANTH_1703	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
ALANTH_1705	ENOG4105E4C	Lytic transglycosylase catalytic
ALANTH_1706	ENOG4105EUJ	GTP cyclohydrolase i
ALANTH_1707	ENOG4105D7N	magnesium and cobalt transport protein CorA
ALANTH_1708	ENOG4105D7Q	type ii secretion system
ALANTH_1709	ENOG4107QHF	type ii secretion system protein e
ALANTH_1712	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
ALANTH_1714	ENOG4105C0P	Mg chelatase subunit ChlI
ALANTH_1715	ENOG4105C8Q	Methyl-accepting chemotaxis
ALANTH_1716	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
ALANTH_1718	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
ALANTH_1719	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
ALANTH_1720	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
ALANTH_1722	ENOG4105CSR	polyphosphate kinase 2
ALANTH_1733	ENOG41082XB	radical SAM domain protein
ALANTH_1734	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
ALANTH_1736	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
ALANTH_1739	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
ALANTH_1741	ENOG4105VB9	50S ribosomal protein l28
ALANTH_1744	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
ALANTH_1745	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
ALANTH_1746	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
ALANTH_1749	ENOG41080IJ	Diacylglycerol kinase
ALANTH_1750	ENOG4105DKP	glycosyl transferase, family 9
ALANTH_1752	ENOG4105M5K	heptosyltransferase
ALANTH_1753	ENOG4106WTF	Glycosyl transferase, family 2
ALANTH_1755	ENOG4105CPK	Glycosyl transferase (Group 1
ALANTH_1758	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
ALANTH_1762	ENOG4107S6X	Glycosyl transferase, family 2
ALANTH_1764	ENOG4105K64	Glycosyl transferase, family 2
ALANTH_1765	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
ALANTH_1767	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
ALANTH_1768	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
ALANTH_1774	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
ALANTH_1779	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
ALANTH_1781	ENOG4105DX0	Hemolysin A
ALANTH_1782	ENOG4105DTN	riboflavin biosynthesis protein ribF
ALANTH_1783	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
ALANTH_1784	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ALANTH_1786	ENOG4105CQB	FAD linked oxidase domain protein
ALANTH_1787	ENOG4107S2Z	UPF0761 membrane protein
ALANTH_1789	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
ALANTH_1790	ENOG4105DJP	Membrane
ALANTH_1791	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
ALANTH_1793	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
ALANTH_1794	ENOG4105M7K	Involved in the transcription termination process (By similarity)
ALANTH_1795	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
ALANTH_1805	ENOG4105BZU	Histidine kinase
ALANTH_1810	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
ALANTH_1811	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
ALANTH_1812	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
ALANTH_1813	ENOG4108VZM	50s ribosomal protein L10
ALANTH_1814	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
ALANTH_1815	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
ALANTH_1816	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
ALANTH_1819	ENOG41086AR	50S ribosomal protein L33
ALANTH_1820	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
ALANTH_1825	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
ALANTH_1826	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
ALANTH_1827	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
ALANTH_1829	ENOG4108JQC	penicillin-binding protein 1A
ALANTH_1830	ENOG4105C5F	glutamine synthetase
ALANTH_1832	ENOG4108ZEX	molybdopterin converting factor, subunit 2
ALANTH_1834	ENOG4108XUR	Pfam:DUF178
ALANTH_1835	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
ALANTH_1836	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
ALANTH_1837	ENOG4105CNI	cell division protein FtsW
ALANTH_1838	ENOG4105CJN	penicillin-binding protein
ALANTH_1839	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
ALANTH_1846	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
ALANTH_1847	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
ALANTH_1848	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
ALANTH_1851	ENOG4105DJG	MaoC domain protein dehydratase
ALANTH_1855	ENOG4105C8Q	Methyl-accepting chemotaxis
ALANTH_1856	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
ALANTH_1861	ENOG4107XWI	flavin reductase domain protein, FMN-binding
ALANTH_1863	ENOG4105D7B	Flagellar biosynthesis protein flha
ALANTH_1864	ENOG4105DTJ	flagellar hook-associated protein
ALANTH_1865	ENOG4108JIR	Flagellum-specific ATP synthase
ALANTH_1867	ENOG4105D00	flagellar biosynthetic protein flhB
ALANTH_1870	ENOG4108ZC9	flagellar basal-body rod protein flgc
ALANTH_1871	ENOG41084DA	flagellar hook-basal body complex protein fliE
ALANTH_1873	ENOG4107R21	site-determining protein
ALANTH_1874	ENOG4105FZW	flagellar biosynthesis regulator FlhF
ALANTH_1878	ENOG4105DD5	Flagellar motor switch protein
ALANTH_1882	ENOG4105BZE	flagellar hook protein, FlgE
ALANTH_1883	ENOG4105BZE	flagellar hook protein, FlgE
ALANTH_1885	ENOG4105DD5	Flagellar motor switch protein
ALANTH_1887	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
ALANTH_1888	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
ALANTH_1889	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
ALANTH_1890	ENOG4105CGA	flagellar basal-body rod protein FlgG
ALANTH_1892	ENOG4108VYJ	response regulator receiver protein
ALANTH_1893	ENOG4105CGA	flagellar basal-body rod protein FlgG
ALANTH_1896	ENOG4105V3S	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
ALANTH_1897	ENOG4105VB6	UPF0109 protein
ALANTH_1898	ENOG4105K5M	30s ribosomal protein S16
ALANTH_1899	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ALANTH_1900	ENOG4108YBP	pseudouridine synthase
ALANTH_1901	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
ALANTH_1903	ENOG4105EGD	dinuclear metal center protein, YbgI family
ALANTH_1904	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
ALANTH_1906	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
ALANTH_1908	ENOG4105CFP	Peptidase U32
ALANTH_1909	ENOG41080BE	Methyl-accepting chemotaxis sensory transducer
ALANTH_1910	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
ALANTH_1911	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
ALANTH_1912	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
ALANTH_1913	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
ALANTH_1914	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
ALANTH_1916	ENOG4105F27	Major Facilitator
ALANTH_1917	ENOG4105D05	Receptor
ALANTH_1920	ENOG4105E2Y	ABC, transporter
ALANTH_1921	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
ALANTH_1922	ENOG4105BZU	Histidine kinase
ALANTH_1923	ENOG4107VQW	regulatoR
ALANTH_1935	ENOG4105DDQ	anthranilate synthase
ALANTH_1941	ENOG4105CNM	Receptor
ALANTH_1950	ENOG4105EYM	Major Facilitator superfamily
ALANTH_1956	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
ALANTH_1958	ENOG4107T5V	SNARE associated Golgi
ALANTH_1959	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
ALANTH_1960	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
ALANTH_1962	ENOG4107QYE	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
ALANTH_1964	ENOG4105C7B	Threonine dehydratase
ALANTH_1965	ENOG4107WJT	it plays a direct role in the translocation of protons across the membrane (By similarity)
ALANTH_1967	ENOG4105YIC	Major outer membrane protein
ALANTH_1968	ENOG4105ENA	helicase
ALANTH_1969	ENOG4105CAS	nag kinase
ALANTH_1970	ENOG4107QID	Threonine synthase
ALANTH_1971	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
ALANTH_1972	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
ALANTH_1975	ENOG4107YV6	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
ALANTH_1977	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
ALANTH_1979	ENOG4107XWN	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
ALANTH_1980	ENOG4105CHR	reductase
ALANTH_1981	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
ALANTH_1982	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
ALANTH_1983	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
ALANTH_1984	ENOG4105K59	histidine triad (HIT) protein
ALANTH_1985	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
ALANTH_1986	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
ALANTH_1987	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
ALANTH_1988	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
ALANTH_1989	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
ALANTH_1990	ENOG4108JQ1	Dehydrogenase
ALANTH_1991	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
ALANTH_1992	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
ALANTH_1993	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
ALANTH_1994	ENOG4105MGB	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
ALANTH_1995	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
ALANTH_1997	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
ALANTH_1999	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
ALANTH_2001	ENOG4105BZR	domain protein
ALANTH_2002	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
ALANTH_2004	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
ALANTH_2007	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
ALANTH_2008	ENOG4105EYK	Phosphatidylglycerophosphatase B
ALANTH_2009	ENOG4107RMM	double-strand break repair protein Addb
ALANTH_2017	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
ALANTH_2018	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
ALANTH_2019	ENOG4107Z7S	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
ALANTH_2020	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
ALANTH_2022	ENOG4105DUM	transcriptional regulator, lysR family
ALANTH_2023	ENOG4105N5T	Radical SAM Protein
ALANTH_2024	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
ALANTH_2025	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
ALANTH_2026	ENOG4105C3M	thioredoxin reductase
ALANTH_2027	ENOG4105K63	Thioredoxin
ALANTH_2028	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
ALANTH_2033	ENOG4105CNM	Receptor
ALANTH_2036	ENOG4105C8Q	Methyl-accepting chemotaxis
ALANTH_2037	ENOG4105C8Q	Methyl-accepting chemotaxis
ALANTH_2042	ENOG4105C0H	protease
ALANTH_2043	ENOG4105C01	Dihydroxy-acid dehydratase
ALANTH_2049	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
ALANTH_2050	ENOG4108TX7	
ALANTH_2052	ENOG4105CN1	protease
ALANTH_2053	ENOG4105C8V	SAICAR synthetase
ALANTH_2054	ENOG4105VR9	phosphoribosylformylglycinamidine synthase
ALANTH_2055	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
ALANTH_2057	ENOG4105E9Q	Acyl-transferase
ALANTH_2059	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
ALANTH_2060	ENOG4105C75	arginyL-tRNA synthetase
ALANTH_2064	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
ALANTH_2067	ENOG4105BZA	Phosphoglycerate kinase
ALANTH_2068	ENOG4105CP7	Triose-phosphate isomerase
ALANTH_2069	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
ALANTH_2070	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
ALANTH_2071	ENOG4105CQC	Prephenate dehydratase
ALANTH_2072	ENOG4105CIH	Imidazole acetol-phosphate transaminase
ALANTH_2073	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
ALANTH_2074	ENOG4105CA0	peroxidase
ALANTH_2075	ENOG4107YJQ	MAF-like protein
ALANTH_2077	ENOG4107TT5	NLP P60 protein
ALANTH_2079	ENOG4107QPK	)-transporter
ALANTH_2082	ENOG4105K63	Thioredoxin
ALANTH_2083	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
ALANTH_2086	ENOG4105BZU	Histidine kinase
ALANTH_2087	ENOG4105DJ4	phosphatidylserine decarboxylase
ALANTH_2089	ENOG4105CA3	membrane-bound lytic murein transglycosylase
ALANTH_2090	ENOG4105CFG	Acts as a chaperone (By similarity)
ALANTH_2091	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ALANTH_2094	ENOG4105NIV	Esterase
ALANTH_2095	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
ALANTH_2098	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
ALANTH_2100	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
ALANTH_2102	ENOG4105CB5	ATP-dependent DNA helicase recG
ALANTH_2103	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
ALANTH_2104	ENOG4105I03	Flagellin
ALANTH_2105	ENOG4105I03	Flagellin
ALANTH_2114	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
ALANTH_2116	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
ALANTH_2117	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
ALANTH_2122	ENOG4105CMR	udp-glucose 4-epimerase
ALANTH_2123	ENOG4105D5D	udp-galactopyranose mutase
ALANTH_2124	ENOG4107VDP	teichoic acid biosynthesis
ALANTH_2126	ENOG4105CHR	reductase
ALANTH_2128	ENOG4105VDT	-acetyltransferase
ALANTH_2130	ENOG4107DKY	pseudaminic acid biosynthesis-associated protein PseG
ALANTH_2131	ENOG4105F0R	Cytidylyltransferase
ALANTH_2132	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
ALANTH_2133	ENOG4105C5E	polysaccharide biosynthesis protein
ALANTH_2135	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
ALANTH_2136	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
ALANTH_2140	ENOG4105D4A	Cell wall formation (By similarity)
ALANTH_2141	ENOG4105E63	Pfam:DUF178
ALANTH_2146	ENOG4105CHH	sulfate transporter
ALANTH_2149	ENOG4105CNH	Multidrug resistance protein MdtL
ALANTH_2151	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
ALANTH_2153	ENOG4105C8J	)-transporter
ALANTH_2155	ENOG4105WPN	DNA integration recombination invertion protein
ALANTH_2156	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
ALANTH_2157	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
ALANTH_2158	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
ALANTH_2159	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
ALANTH_2164	ENOG4105CJW	magnesium transporter
ALANTH_2165	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
ALANTH_2168	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
ALANTH_2175	ENOG4105HFZ	Membrane
ALANTH_2176	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
ALANTH_2178	ENOG4105NU9	Preprotein translocase subunit SecG
ALANTH_2179	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
ALANTH_2180	ENOG4107VCP	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
ALANTH_2182	ENOG4105D8G	Major Facilitator superfamily
ALANTH_2183	ENOG4107RX3	Mg2 transporter protein cora family protein
ALANTH_2184	ENOG410802Z	Protein of unknown function (DUF328)
ALANTH_2185	ENOG4108JYZ	YitT family
ALANTH_2186	ENOG41082NP	Multiple antibiotic resistance
ALANTH_2189	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
ALANTH_2190	ENOG4105C26	Dehydrogenase
ALANTH_2191	ENOG4105C7K	acetolactate synthase
ALANTH_2192	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
ALANTH_2193	ENOG4108RMU	ferritin dps family protein
ALANTH_2194	ENOG4105C2C	drug resistance transporter, Bcr CflA
ALANTH_2195	ENOG4105C8Q	Methyl-accepting chemotaxis
ALANTH_2197	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
ALANTH_2198	ENOG4105BZS	acriflavin resistance protein
ALANTH_2199	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
ALANTH_2201	ENOG4105CBX	hi0933 family
ALANTH_2205	ENOG4105C6T	cysteine synthase
ALANTH_2207	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
ALANTH_2208	ENOG4105C11	sulfate adenylyltransferase), subunit 2
ALANTH_2209	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
ALANTH_2211	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
ALANTH_2214	ENOG4107RN3	metallophosphoesterase
ALANTH_2220	ENOG41080T7	secreted protein
ALANTH_2222	ENOG4105C8Q	Methyl-accepting chemotaxis
ALANTH_2223	ENOG4108IJ6	ABC transporter
ALANTH_2225	ENOG4108I5D	sulfate abc transporter
ALANTH_2226	ENOG4105BZU	Histidine kinase
ALANTH_2229	ENOG4105D7W	serine acetyltransferase
ALANTH_2230	ENOG4105C9B	Cysteine desulfurase
ALANTH_2231	ENOG4105ESN	nucleotide-binding protein
ALANTH_2235	ENOG4105C6T	cysteine synthase
ALANTH_2236	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
ALANTH_2241	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
ALANTH_2242	ENOG4105GVF	(ABC) transporter
ALANTH_2244	ENOG4105E2Y	ABC, transporter
ALANTH_2245	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
ALANTH_2246	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
ALANTH_2247	ENOG4105GVF	(ABC) transporter
ALANTH_2248	ENOG4105CDA	abc transporter atp-binding protein
ALANTH_2249	ENOG4105DRP	amino acid AbC transporter
ALANTH_2250	ENOG4105E5Q	amino acid AbC transporter
ALANTH_2253	ENOG4105CI3	gtp-binding protein typa
ALANTH_2256	ENOG4105D05	Receptor
ALANTH_2257	ENOG4105D05	Receptor
ALANTH_2258	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
ALANTH_2259	ENOG4105EHG	Permease protein
ALANTH_2260	ENOG4107R4I	Periplasmic binding protein
ALANTH_2261	ENOG4105PYN	Pyridoxamine 5-phosphate oxidase-related
ALANTH_2263	ENOG4105BZ1	(ABC) transporter
ALANTH_2265	ENOG41066VF	YeeE YedE family protein
ALANTH_2267	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
ALANTH_2270	ENOG4107R2U	Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity)
ALANTH_2271	ENOG4105EN6	Membrane
ALANTH_2277	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)