locus-tag	class	description
ALEK_0001	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
ALEK_0002	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
ALEK_0003	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
ALEK_0006	ENOG4105CAY	ferredoxin--nadp reductase
ALEK_0007	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
ALEK_0012	ENOG4105EI2	Pseudouridine synthase
ALEK_0013	ENOG4107QTF	adenylosuccinate lyase
ALEK_0014	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
ALEK_0015	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
ALEK_0019	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
ALEK_0027	ENOG4105BZ8	glutamate synthase
ALEK_0028	ENOG4105UYK	outer membrane protein a
ALEK_0034	ENOG4107QKV	phosphomannomutase
ALEK_0035	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
ALEK_0038	ENOG4107VQW	regulatoR
ALEK_0039	ENOG4105BZU	Histidine kinase
ALEK_0041	ENOG4105C58	cytochrome c oxidase accessory protein ccog
ALEK_0042	ENOG4105N14	lysine exporter protein LysE YggA
ALEK_0046	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
ALEK_0048	ENOG4105KVH	Transcriptional regulator
ALEK_0053	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
ALEK_0054	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
ALEK_0055	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
ALEK_0057	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
ALEK_0059	ENOG4105CH5	extracellular solute-binding protein, family 7
ALEK_0061	ENOG4108F01	MaoC domain protein
ALEK_0063	ENOG4105C1G	acyl-Coa dehydrogenase
ALEK_0064	ENOG4105DF6	Fe-S oxidoreductase
ALEK_0065	ENOG4105BZJ	Electron transfer flavoprotein
ALEK_0066	ENOG4105C10	Electron transfer flavoprotein
ALEK_0067	ENOG4105FQ6	thiopurine methyltransferase
ALEK_0068	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
ALEK_0069	ENOG4105KA0	thioesterase Superfamily protein
ALEK_0070	ENOG4107YD3	Thioesterase
ALEK_0071	ENOG4107QP7	CoA-transferase subunit A
ALEK_0073	ENOG4105CHU	acetyl-coa acetyltransferase
ALEK_0074	ENOG4105BZU	Histidine kinase
ALEK_0076	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
ALEK_0077	ENOG4105BZU	Histidine kinase
ALEK_0078	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
ALEK_0079	ENOG4107QR9	Iron-sulfur cluster binding protein
ALEK_0080	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
ALEK_0082	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
ALEK_0083	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
ALEK_0084	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
ALEK_0085	ENOG4105C1J	atp-dependent rna helicase
ALEK_0087	ENOG4105CJ3	phosphate transporter
ALEK_0088	ENOG4108PYU	two-component system response regulator
ALEK_0090	ENOG4105CAQ	asparagine synthetase
ALEK_0092	ENOG4105E7Q	Cob(II)yrinic acid a,c-diamide reductase
ALEK_0093	ENOG4105CH5	extracellular solute-binding protein, family 7
ALEK_0095	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
ALEK_0097	ENOG4108IAB	Phoh family
ALEK_0098	ENOG4108YXA	Membrane
ALEK_0099	ENOG4105D1H	recombination factor protein RarA
ALEK_0100	ENOG4105FE9	pseudouridine synthase
ALEK_0101	ENOG4105C2X	Arabinose 5-phosphate isomerase
ALEK_0103	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
ALEK_0104	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
ALEK_0107	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
ALEK_0108	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
ALEK_0109	ENOG4105VFU	Rna-binding protein
ALEK_0110	ENOG4105C8Q	Methyl-accepting chemotaxis
ALEK_0116	ENOG4108IJF	Heavy metal efflux pump, CzcA
ALEK_0118	ENOG4105E18	UPF0276 protein
ALEK_0121	ENOG4105D6E	homoserine dehydrogenase
ALEK_0122	ENOG4105CHM	Aminotransferase
ALEK_0126	ENOG41082DI	50s ribosomal protein l31
ALEK_0127	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
ALEK_0130	ENOG41064RH	membrane protein YliF
ALEK_0133	ENOG4105C8Q	Methyl-accepting chemotaxis
ALEK_0134	ENOG4105BZU	Histidine kinase
ALEK_0135	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
ALEK_0137	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
ALEK_0138	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
ALEK_0139	ENOG41084QV	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
ALEK_0140	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
ALEK_0141	ENOG4105C8Q	Methyl-accepting chemotaxis
ALEK_0142	ENOG4105C2C	drug resistance transporter, Bcr CflA
ALEK_0143	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
ALEK_0144	ENOG4105C2I	pirin domain protein
ALEK_0146	ENOG4108YYH	Nadph-dependent fmn reductase
ALEK_0147	ENOG4108YYC	ycei family
ALEK_0149	ENOG410829K	Lysine exporter protein (Lyse ygga)
ALEK_0150	ENOG4107UUH	Aminotransferase
ALEK_0151	ENOG4105CYE	ATP phosphoribosyltransferase regulatory subunit
ALEK_0152	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
ALEK_0154	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
ALEK_0156	ENOG4105KVH	Transcriptional regulator
ALEK_0159	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
ALEK_0161	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
ALEK_0164	ENOG4105D1F	ATP-binding protein
ALEK_0165	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
ALEK_0168	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
ALEK_0171	ENOG4105CM2	brancheD-chain amino acid aminotransferase
ALEK_0174	ENOG4105MSB	protein, conserved in bacteria
ALEK_0176	ENOG4105DIK	(ABC) transporter
ALEK_0183	ENOG410624X	efflux transporter, rnd family, mfp subunit
ALEK_0186	ENOG4105YIC	Major outer membrane protein
ALEK_0187	ENOG4108I6A	alcohol dehydrogenase
ALEK_0188	ENOG4105CF7	AraC family transcriptional regulator
ALEK_0189	ENOG4108I6A	alcohol dehydrogenase
ALEK_0190	ENOG4105CF7	AraC family transcriptional regulator
ALEK_0191	ENOG4107QY8	reductase
ALEK_0193	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
ALEK_0198	ENOG4106KXD	ATP-dependent carboxylate-amine ligase (By similarity)
ALEK_0204	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
ALEK_0206	ENOG4105CXC	rtn protein
ALEK_0207	ENOG4108KK1	membrane protein AbrB duplication
ALEK_0209	ENOG4107B2H	carbonic anhydrase
ALEK_0211	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
ALEK_0215	ENOG4105KVH	Transcriptional regulator
ALEK_0216	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
ALEK_0217	ENOG4105DDK	oxidoreductase, beta subunit
ALEK_0218	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
ALEK_0220	ENOG4105EJ5	oxidoreductase gamma subunit
ALEK_0221	ENOG4107XGZ	Hydrolase
ALEK_0223	ENOG4108UJD	30S ribosomal protein S9
ALEK_0224	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
ALEK_0225	ENOG4105BZU	Histidine kinase
ALEK_0226	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
ALEK_0228	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
ALEK_0229	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
ALEK_0230	ENOG4105E2Z	phosphate ABC transporter (Permease
ALEK_0231	ENOG4105C8U	phosphate abc transporter
ALEK_0232	ENOG4108M8H	domain protein
ALEK_0235	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
ALEK_0236	ENOG4108317	Binds directly to 16S ribosomal RNA (By similarity)
ALEK_0237	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
ALEK_0238	ENOG410813J	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
ALEK_0239	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
ALEK_0243	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
ALEK_0244	ENOG41084M8	50s ribosomal protein L35
ALEK_0245	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
ALEK_0254	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
ALEK_0258	ENOG4105C0W	non-ribosomal peptide synthetase
ALEK_0261	ENOG4105CJ1	ABC, transporter
ALEK_0266	ENOG4105CHR	reductase
ALEK_0267	ENOG4105C84	Histidine ammonia-lyase
ALEK_0271	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
ALEK_0272	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
ALEK_0277	ENOG4105KNE	Phosphatidate cytidylyltransferase
ALEK_0278	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
ALEK_0282	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
ALEK_0283	ENOG4108ZJT	translation initiation factor, Sui1
ALEK_0284	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
ALEK_0285	ENOG4105VF7	tolerance protein
ALEK_0286	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
ALEK_0305	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
ALEK_0311	ENOG4105CN1	protease
ALEK_0312	ENOG4105C8V	SAICAR synthetase
ALEK_0313	ENOG4105VR9	phosphoribosylformylglycinamidine synthase
ALEK_0314	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
ALEK_0316	ENOG4105E9Q	Acyl-transferase
ALEK_0317	ENOG4105WMR	Protein CrcB homolog
ALEK_0318	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
ALEK_0319	ENOG4105C75	arginyL-tRNA synthetase
ALEK_0321	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
ALEK_0323	ENOG4105BZA	Phosphoglycerate kinase
ALEK_0324	ENOG4105CP7	Triose-phosphate isomerase
ALEK_0325	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
ALEK_0326	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
ALEK_0327	ENOG4105CQC	Prephenate dehydratase
ALEK_0328	ENOG4105CIH	Imidazole acetol-phosphate transaminase
ALEK_0329	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
ALEK_0331	ENOG4105E7Q	Cob(II)yrinic acid a,c-diamide reductase
ALEK_0336	ENOG4105C26	Dehydrogenase
ALEK_0340	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
ALEK_0343	ENOG4105G3Z	GntR family transcriptional regulator
ALEK_0344	ENOG4108KJ1	Trap dicarboxylate transporter, dctp subunit
ALEK_0346	ENOG4108K1J	Transporter DctQ
ALEK_0347	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
ALEK_0348	ENOG4107RCH	Diaminopropionate ammonia-lyase
ALEK_0349	ENOG4107S4Y	M20 DapE family protein YgeY
ALEK_0352	ENOG4105C5W	Aldolase
ALEK_0355	ENOG4107YJQ	MAF-like protein
ALEK_0358	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
ALEK_0359	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
ALEK_0365	ENOG4105DHT	Metal Dependent Phosphohydrolase
ALEK_0368	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
ALEK_0376	ENOG4105HF0	Membrane
ALEK_0382	ENOG4105DIV	Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD( ) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds (By similarity)
ALEK_0383	ENOG4105DF3	Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds (By similarity)
ALEK_0386	ENOG4105DEN	Luciferase family
ALEK_0387	ENOG4108JNI	Alpha beta hydrolase
ALEK_0391	ENOG4107TT5	NLP P60 protein
ALEK_0392	ENOG4107TT5	NLP P60 protein
ALEK_0396	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
ALEK_0397	ENOG4105K63	Thioredoxin
ALEK_0398	ENOG4105K63	Thioredoxin
ALEK_0399	ENOG4107QPK	)-transporter
ALEK_0400	ENOG4105BZU	Histidine kinase
ALEK_0401	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
ALEK_0402	ENOG4105BZG	amino acid carrier protein
ALEK_0403	ENOG4105C3M	thioredoxin reductase
ALEK_0404	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
ALEK_0405	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
ALEK_0406	ENOG4105N5T	Radical SAM Protein
ALEK_0407	ENOG4105DUM	transcriptional regulator, lysR family
ALEK_0408	ENOG4105C4R	Atp-dependent dna helicase
ALEK_0409	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
ALEK_0410	ENOG4107Z7S	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
ALEK_0411	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
ALEK_0412	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
ALEK_0421	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
ALEK_0425	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
ALEK_0427	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
ALEK_0430	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
ALEK_0432	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
ALEK_0434	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
ALEK_0435	ENOG4105MGB	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
ALEK_0436	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
ALEK_0438	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
ALEK_0439	ENOG4108JQ1	Dehydrogenase
ALEK_0440	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
ALEK_0441	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
ALEK_0442	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
ALEK_0443	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
ALEK_0444	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
ALEK_0445	ENOG4105K59	histidine triad (HIT) protein
ALEK_0446	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
ALEK_0447	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
ALEK_0448	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
ALEK_0449	ENOG4105CHR	reductase
ALEK_0450	ENOG4107SPB	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
ALEK_0452	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
ALEK_0453	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
ALEK_0455	ENOG4107YV6	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
ALEK_0458	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
ALEK_0459	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
ALEK_0460	ENOG4107QID	Threonine synthase
ALEK_0461	ENOG4105CAS	nag kinase
ALEK_0462	ENOG4105BZU	Histidine kinase
ALEK_0463	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
ALEK_0465	ENOG4107WJT	it plays a direct role in the translocation of protons across the membrane (By similarity)
ALEK_0466	ENOG4105C7B	Threonine dehydratase
ALEK_0467	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
ALEK_0468	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
ALEK_0470	ENOG4107T5V	SNARE associated Golgi
ALEK_0472	ENOG4105DKW	ABC transporter
ALEK_0474	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
ALEK_0476	ENOG4105CIF	Ornithine Cyclodeaminase
ALEK_0477	ENOG4105CTU	Proline racemase
ALEK_0478	ENOG4105F4E	fad dependent oxidoreductase
ALEK_0479	ENOG4108HW3	(ABC) transporter
ALEK_0480	ENOG4105DSP	amino acid AbC transporter
ALEK_0481	ENOG4105E5Q	amino acid AbC transporter
ALEK_0482	ENOG4105CDA	abc transporter atp-binding protein
ALEK_0483	ENOG4107WEA	mandelate racemase muconate lactonizing
ALEK_0485	ENOG4105CTU	Proline racemase
ALEK_0491	ENOG4105C32	Amino acid ABC transporter (Permease)
ALEK_0492	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
ALEK_0493	ENOG4105C0Z	ABC transporter
ALEK_0494	ENOG4108IV0	ABC, transporter
ALEK_0495	ENOG4105C26	Dehydrogenase
ALEK_0497	ENOG4105C8Q	Methyl-accepting chemotaxis
ALEK_0505	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
ALEK_0509	ENOG4105KCK	Peptidoglycan-associated lipoprotein
ALEK_0511	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
ALEK_0516	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
ALEK_0517	ENOG4105WH1	Two component transcriptional regulator luxr family
ALEK_0521	ENOG4107QYG	anthranilate phosphoribosyltransferase
ALEK_0526	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
ALEK_0528	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
ALEK_0536	ENOG4108VKQ	nitriC oxide reductase
ALEK_0538	ENOG4107VQW	regulatoR
ALEK_0541	ENOG4105CNM	Receptor
ALEK_0542	ENOG4105BZU	Histidine kinase
ALEK_0551	ENOG4105CE1	Ferrous iron transport protein b
ALEK_0554	ENOG410822N	TonB family
ALEK_0555	ENOG4109015	Biopolymer transport protein exbD tolR
ALEK_0561	ENOG4107RBR	Receptor
ALEK_0562	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
ALEK_0565	ENOG4105CIS	alcohol dehydrogenase
ALEK_0572	ENOG4108ZMS	Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity)
ALEK_0573	ENOG4105GXZ	Ferredoxin-type protein NapH
ALEK_0574	ENOG4108BGM	Quinol dehydrogenase periplasmic component
ALEK_0575	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
ALEK_0577	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
ALEK_0579	ENOG4105C8Q	Methyl-accepting chemotaxis
ALEK_0580	ENOG4105EJQ	L-serine dehydratase
ALEK_0581	ENOG4105CDA	abc transporter atp-binding protein
ALEK_0582	ENOG4105DRP	amino acid AbC transporter
ALEK_0583	ENOG4105EZ7	amino acid ABC transporter
ALEK_0584	ENOG4107QXX	ABC transporter
ALEK_0585	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
ALEK_0588	ENOG4108I0Q	anthranilate phosphoribosyltransferase
ALEK_0589	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
ALEK_0590	ENOG4105BZU	Histidine kinase
ALEK_0592	ENOG4105C8Q	Methyl-accepting chemotaxis
ALEK_0593	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
ALEK_0595	ENOG4108KA0	Inherit from COG: Phosphoesterase, DHHA1
ALEK_0596	ENOG4105K4P	CoA-binding domain protein
ALEK_0597	ENOG4105DHQ	Histidine kinase
ALEK_0598	ENOG4105ETX	regulatoR
ALEK_0599	ENOG4105EIN	peptidylprolyl cis-trans isomerase
ALEK_0600	ENOG4105D2N	Aldolase
ALEK_0603	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
ALEK_0607	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
ALEK_0608	ENOG4105D7T	ABC transporter
ALEK_0614	ENOG4105DZG	Dehydrogenase
ALEK_0616	ENOG41086XE	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ (By similarity)
ALEK_0617	ENOG4105WF7	pyrroloquinoline quinone biosynthesis protein d
ALEK_0618	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
ALEK_0621	ENOG4105BZU	Histidine kinase
ALEK_0622	ENOG4105C26	Dehydrogenase
ALEK_0624	ENOG4105M8F	Biopolymer transport protein exbD tolR
ALEK_0625	ENOG4105M8K	biopolymer transport protein
ALEK_0627	ENOG4105BZU	Histidine kinase
ALEK_0628	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
ALEK_0629	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
ALEK_0632	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
ALEK_0633	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
ALEK_0635	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
ALEK_0637	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
ALEK_0638	ENOG4105VIE	preprotein translocase, subunit YajC
ALEK_0639	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
ALEK_0640	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
ALEK_0645	ENOG4105C8T	Leucyl-tRNA synthetase
ALEK_0647	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
ALEK_0648	ENOG4105DR5	peptidase
ALEK_0650	ENOG4105C1J	atp-dependent rna helicase
ALEK_0651	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
ALEK_0659	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
ALEK_0663	ENOG4106MP8	UPF0754 membrane protein
ALEK_0664	ENOG4105D7X	high-affinity nickel-transporter
ALEK_0668	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
ALEK_0669	ENOG4105EKE	dihydroorotase
ALEK_0670	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
ALEK_0671	ENOG4105GR3	Histidine kinase
ALEK_0673	ENOG4108JA2	transcriptioN-repair coupling factor
ALEK_0674	ENOG4105E09	nadh pyrophosphatase
ALEK_0677	ENOG4105CBX	hi0933 family
ALEK_0686	ENOG4105CBX	hi0933 family
ALEK_0687	ENOG4105D48	metallophosphoesterase
ALEK_0691	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
ALEK_0692	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
ALEK_0693	ENOG4108V3W	Chemotaxis protein, CheW
ALEK_0695	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
ALEK_0696	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
ALEK_0698	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
ALEK_0699	ENOG41084FT	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
ALEK_0701	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
ALEK_0702	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
ALEK_0704	ENOG4108K01	transcriptional regulator
ALEK_0707	ENOG4107YTP	response regulator receiver protein
ALEK_0708	ENOG4105ECY	inositol monophosphatase
ALEK_0710	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
ALEK_0711	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
ALEK_0712	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
ALEK_0713	ENOG4107W1P	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
ALEK_0714	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
ALEK_0717	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
ALEK_0718	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
ALEK_0719	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
ALEK_0722	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
ALEK_0726	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
ALEK_0730	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
ALEK_0733	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
ALEK_0735	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
ALEK_0737	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
ALEK_0738	ENOG4108ZG0	Ompa motb domain protein
ALEK_0739	ENOG4105CDV	Ompa motb domain protein
ALEK_0740	ENOG4105CDV	Ompa motb domain protein
ALEK_0741	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
ALEK_0742	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
ALEK_0743	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
ALEK_0744	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ALEK_0745	ENOG4105DC7	peptidase M24
ALEK_0746	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
ALEK_0747	ENOG4107SYB	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
ALEK_0749	ENOG4105C1J	atp-dependent rna helicase
ALEK_0751	ENOG4108IJ2	phosphate acetyltransferase
ALEK_0752	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
ALEK_0753	ENOG41083X2	DNA polymerase III, epsilon subunit
ALEK_0755	ENOG4107QN1	sodium solute
ALEK_0757	ENOG4107QN1	sodium solute
ALEK_0759	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
ALEK_0761	ENOG4107QN1	sodium solute
ALEK_0763	ENOG4108STX	response regulator
ALEK_0764	ENOG4105BZU	Histidine kinase
ALEK_0785	ENOG4105CEV	competence damage-inducible protein
ALEK_0786	ENOG4107RSR	Malate quinone oxidoreductase
ALEK_0787	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
ALEK_0791	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
ALEK_0796	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
ALEK_0798	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
ALEK_0801	ENOG4105CE9	30S ribosomal protein S2
ALEK_0802	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
ALEK_0803	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
ALEK_0805	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
ALEK_0806	ENOG4105BZU	Histidine kinase
ALEK_0807	ENOG4105C59	p-type ATPase
ALEK_0810	ENOG4105EFJ	Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity)
ALEK_0811	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
ALEK_0813	ENOG41074MP	UPF0103 Mediator of ErbB2-driven cell motility-containing protein
ALEK_0814	ENOG4107S90	membrAne
ALEK_0815	ENOG4105FDK	ABC transporter
ALEK_0817	ENOG4105QNR	S1 RNA binding domain protein
ALEK_0818	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
ALEK_0820	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
ALEK_0821	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
ALEK_0822	ENOG4105ENA	helicase
ALEK_0824	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
ALEK_0826	ENOG4105BZS	acriflavin resistance protein
ALEK_0829	ENOG4107RDB	Major Facilitator
ALEK_0830	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
ALEK_0835	ENOG410901F	(LipO)protein
ALEK_0836	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
ALEK_0839	ENOG4106AXJ	AraC family transcriptional regulator
ALEK_0840	ENOG4108VP3	Lysine exporter protein (LysE YggA)
ALEK_0845	ENOG4105C8Q	Methyl-accepting chemotaxis
ALEK_0846	ENOG4105D64	Mechanosensitive ion channel
ALEK_0853	ENOG4105C8Q	Methyl-accepting chemotaxis
ALEK_0854	ENOG41084IH	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
ALEK_0855	ENOG4105C8Q	Methyl-accepting chemotaxis
ALEK_0863	ENOG4105CHR	reductase
ALEK_0865	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
ALEK_0868	ENOG4105CK2	sodium dicarboxylate symporter
ALEK_0871	ENOG4106AXJ	AraC family transcriptional regulator
ALEK_0872	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
ALEK_0877	ENOG4105D7X	high-affinity nickel-transporter
ALEK_0881	ENOG4105C28	cystathionine
ALEK_0886	ENOG4105DWY	Agmatine deiminase
ALEK_0889	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
ALEK_0891	ENOG4105K63	Thioredoxin
ALEK_0892	ENOG4105CNG	UPF0061 protein
ALEK_0894	ENOG41067SE	Tetr family transcriptional regulator
ALEK_0897	ENOG4105BZS	acriflavin resistance protein
ALEK_0901	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
ALEK_0907	ENOG4105JSC	dimethylmenaquinone methyltransferase
ALEK_0908	ENOG4105D3Y	Na H antiporter
ALEK_0910	ENOG4105BZU	Histidine kinase
ALEK_0911	ENOG4105VG1	fes assembly suf system protein
ALEK_0912	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
ALEK_0915	ENOG4105C3K	feS assembly ATPase SufC
ALEK_0917	ENOG4105E5Q	amino acid AbC transporter
ALEK_0918	ENOG4105EAB	amino acid AbC transporter
ALEK_0919	ENOG4105C3J	Cysteine desulfurase
ALEK_0924	ENOG4105FQT	
ALEK_0925	ENOG4105CH7	arginosuccinase
ALEK_0927	ENOG4105CUZ	uba thif-type nad fad binding protein
ALEK_0928	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
ALEK_0929	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
ALEK_0933	ENOG4105CSM	endonuclease III
ALEK_0934	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
ALEK_0938	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
ALEK_0942	ENOG4108YZG	isomerase
ALEK_0943	ENOG4105C3F	Signal peptidase i
ALEK_0944	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
ALEK_0945	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
ALEK_0946	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
ALEK_0949	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
ALEK_0951	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
ALEK_0953	ENOG410692R	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
ALEK_0954	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
ALEK_0956	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
ALEK_0957	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
ALEK_0958	ENOG4105CRQ	synthase (Component I)
ALEK_0960	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
ALEK_0961	ENOG4105CRK	lysyL-tRNA synthetase
ALEK_0963	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
ALEK_0964	ENOG4105CDU	Replicative dna helicase
ALEK_0972	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
ALEK_0973	ENOG4107QP8	phosphohexose isomerase
ALEK_0974	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
ALEK_0977	ENOG4107QQG	Dehydrogenase
ALEK_0978	ENOG4105D2T	synthase
ALEK_0979	ENOG4107SE4	UDP-N-acetylglucosamine 2-epimerase
ALEK_0980	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
ALEK_0983	ENOG4105F0R	Cytidylyltransferase
ALEK_0986	ENOG4105D2T	synthase
ALEK_0987	ENOG4107SE4	UDP-N-acetylglucosamine 2-epimerase
ALEK_0993	ENOG4107T4Z	adenosine kinase
ALEK_1003	ENOG4105CPQ	Dehydrogenase
ALEK_1006	ENOG4105ESV	Glycosyl transferase, family 4
ALEK_1010	ENOG4107QKV	phosphomannomutase
ALEK_1011	ENOG4105CMR	udp-glucose 4-epimerase
ALEK_1012	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
ALEK_1013	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
ALEK_1015	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
ALEK_1016	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
ALEK_1017	ENOG4108ZMS	Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity)
ALEK_1018	ENOG4108ZMS	Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity)
ALEK_1020	ENOG4105CVR	type I restriction-modification system
ALEK_1021	ENOG41082EK	Restriction modification system DNA (Specificity
ALEK_1026	ENOG4105DZR	Type I site-specific deoxyribonuclease
ALEK_1028	ENOG4108C33	Resolvase
ALEK_1041	ENOG4105C3G	gtp-binding protein
ALEK_1046	ENOG4105NBK	UPF0345 protein
ALEK_1049	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
ALEK_1050	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
ALEK_1052	ENOG4105C8Q	Methyl-accepting chemotaxis
ALEK_1053	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
ALEK_1054	ENOG4105CPF	Cell wall formation (By similarity)
ALEK_1056	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
ALEK_1065	ENOG41062JF	Transcriptional regulator
ALEK_1071	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
ALEK_1072	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
ALEK_1073	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
ALEK_1074	ENOG4105KZZ	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
ALEK_1075	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ALEK_1076	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
ALEK_1077	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
ALEK_1078	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
ALEK_1079	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
ALEK_1080	ENOG41084HJ	50s ribosomal protein l29
ALEK_1081	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
ALEK_1082	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
ALEK_1083	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
ALEK_1084	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ALEK_1085	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
ALEK_1086	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
ALEK_1087	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
ALEK_1088	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
ALEK_1089	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
ALEK_1090	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
ALEK_1091	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
ALEK_1092	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
ALEK_1093	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
ALEK_1095	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
ALEK_1097	ENOG4105C9M	aspartyl-trna synthetase
ALEK_1100	ENOG4105CCT	upf0313 protein
ALEK_1101	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
ALEK_1102	ENOG4105C8Q	Methyl-accepting chemotaxis
ALEK_1105	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
ALEK_1106	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
ALEK_1111	ENOG4108V06	Glutathione peroxidase
ALEK_1112	ENOG4105BZU	Histidine kinase
ALEK_1117	ENOG4105DAA	L-lactate
ALEK_1119	ENOG4105BZU	Histidine kinase
ALEK_1126	ENOG41080BE	Methyl-accepting chemotaxis sensory transducer
ALEK_1126	ENOG41080BE	Methyl-accepting chemotaxis sensory transducer
ALEK_1129	ENOG4105MEW	serine threonine protein phosphatase
ALEK_1130	ENOG4105D17	glycoside hydrolase, family 3 domain protein
ALEK_1136	ENOG4105CGK	Exodeoxyribonuclease III
ALEK_1145	ENOG4105DCM	major facilitator superfamily
ALEK_1150	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
ALEK_1160	ENOG4105D5U	fad dependent oxidoreductase
ALEK_1161	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
ALEK_1162	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
ALEK_1166	ENOG4105CQZ	Histidine kinase
ALEK_1167	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
ALEK_1168	ENOG4108IJ0	Aspartate ammonia-lyase
ALEK_1170	ENOG41090A1	ferritin
ALEK_1172	ENOG4105BZU	Histidine kinase
ALEK_1174	ENOG4105BZU	Histidine kinase
ALEK_1176	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
ALEK_1178	ENOG4105F1N	DNA alkylation repair
ALEK_1179	ENOG4108Z66	YbaK ebsC protein
ALEK_1180	ENOG4105C7I	Dehydrogenase
ALEK_1185	ENOG4105F1S	paraquat-inducible protein a
ALEK_1186	ENOG4105DY2	Paraquat-inducible protein b
ALEK_1187	ENOG4105C94	Transporter
ALEK_1188	ENOG4108IJ7	Glycine betaine
ALEK_1189	ENOG4108HQS	Glycine betaine
ALEK_1190	ENOG4105GIJ	Glycine betaine
ALEK_1192	ENOG4105GIJ	Glycine betaine
ALEK_1194	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
ALEK_1197	ENOG4105CGD	Nad-dependent epimerase dehydratase
ALEK_1200	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
ALEK_1205	ENOG4105EGI	Transcriptional regulator
ALEK_1209	ENOG4105C8Q	Methyl-accepting chemotaxis
ALEK_1210	ENOG4108JYZ	YitT family
ALEK_1212	ENOG4105C8Q	Methyl-accepting chemotaxis
ALEK_1221	ENOG4105BZS	acriflavin resistance protein
ALEK_1222	ENOG4105ETX	regulatoR
ALEK_1226	ENOG4105C8Q	Methyl-accepting chemotaxis
ALEK_1231	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
ALEK_1236	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
ALEK_1241	ENOG4108URH	decarboxylase
ALEK_1243	ENOG4105DHT	Metal Dependent Phosphohydrolase
ALEK_1244	ENOG4107VQW	regulatoR
ALEK_1245	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
ALEK_1247	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
ALEK_1249	ENOG4105E7W	lamb ycsf family protein
ALEK_1253	ENOG4105BZU	Histidine kinase
ALEK_1256	ENOG4105C8Q	Methyl-accepting chemotaxis
ALEK_1257	ENOG4105C1J	atp-dependent rna helicase
ALEK_1258	ENOG4105BZU	Histidine kinase
ALEK_1259	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
ALEK_1261	ENOG4105D05	Receptor
ALEK_1262	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
ALEK_1263	ENOG4105E2Y	ABC, transporter
ALEK_1268	ENOG4107ENK	receptor
ALEK_1269	ENOG41074H6	response regulator
ALEK_1273	ENOG4105C8Q	Methyl-accepting chemotaxis
ALEK_1274	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
ALEK_1275	ENOG4105BZU	Histidine kinase
ALEK_1277	ENOG4108IAB	Phoh family
ALEK_1281	ENOG4105BZU	Histidine kinase
ALEK_1282	ENOG4105CJZ	response regulator
ALEK_1284	ENOG4105EQK	-acetyltransferase
ALEK_1285	ENOG4107ZIC	Glycerol-3-phosphate cytidylyltransferase
ALEK_1287	ENOG4108JYZ	YitT family
ALEK_1290	ENOG4105BZU	Histidine kinase
ALEK_1291	ENOG4105BZU	Histidine kinase
ALEK_1292	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
ALEK_1300	ENOG4105E5Q	amino acid AbC transporter
ALEK_1301	ENOG4105EAB	amino acid AbC transporter
ALEK_1304	ENOG4105EM7	Selenocysteine-specific translation elongation factor
ALEK_1305	ENOG4105C1Y	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis (By similarity)
ALEK_1310	ENOG4105BZU	Histidine kinase
ALEK_1311	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
ALEK_1312	ENOG4105BZU	Histidine kinase
ALEK_1313	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
ALEK_1314	ENOG4107T9Q	phosphonate abc transporter
ALEK_1315	ENOG4108VA1	ABC transporter
ALEK_1316	ENOG4105S7S	phosphonate abc transporter
ALEK_1320	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
ALEK_1327	ENOG4105QAX	Iron-sulfur
ALEK_1329	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
ALEK_1333	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
ALEK_1334	ENOG4105C8W	ABC transporter
ALEK_1335	ENOG4107A5B	Binding-protein-dependent transport systems, inner membrane component
ALEK_1347	ENOG4108R99	pseudouridine synthase
ALEK_1349	ENOG4105BZU	Histidine kinase
ALEK_1350	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
ALEK_1363	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
ALEK_1370	ENOG4105KME	endoribonuclease L-psp
ALEK_1371	ENOG4107QMZ	Dehydrogenase
ALEK_1372	ENOG4105BZG	amino acid carrier protein
ALEK_1373	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
ALEK_1374	ENOG4105CCF	Lysine exporter protein (Lyse ygga)
ALEK_1375	ENOG4108DMH	HTH_ARAC
ALEK_1376	ENOG4105DF3	Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds (By similarity)
ALEK_1379	ENOG4105I93	response regulator
ALEK_1381	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
ALEK_1388	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
ALEK_1394	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
ALEK_1395	ENOG4105BZU	Histidine kinase
ALEK_1396	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
ALEK_1398	ENOG4105BZU	Histidine kinase
ALEK_1400	ENOG4108V3W	Chemotaxis protein, CheW
ALEK_1401	ENOG4105C8Q	Methyl-accepting chemotaxis
ALEK_1402	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
ALEK_1403	ENOG4105CBS	Chea signal transduction histidine kinase
ALEK_1405	ENOG4107YTP	response regulator receiver protein
ALEK_1406	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
ALEK_1409	ENOG410812K	response regulator receiver protein
ALEK_1410	ENOG4105BZU	Histidine kinase
ALEK_1413	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
ALEK_1422	ENOG4105BZU	Histidine kinase
ALEK_1424	ENOG4105KCK	Peptidoglycan-associated lipoprotein
ALEK_1425	ENOG4107R7Y	intracellular protease Pfpi family
ALEK_1426	ENOG4105J4Q	Transcriptional regulator
ALEK_1429	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
ALEK_1434	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
ALEK_1439	ENOG4105CHM	Aminotransferase
ALEK_1441	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
ALEK_1446	ENOG410903C	(LipO)protein
ALEK_1447	ENOG4105DR5	peptidase
ALEK_1448	ENOG4105DAN	ATP-dependent protease
ALEK_1449	ENOG4108IJ0	Aspartate ammonia-lyase
ALEK_1450	ENOG4105CDY	transcriptional regulatory protein
ALEK_1459	ENOG4105CJ2	(LipO)protein
ALEK_1460	ENOG4105ERG	peptidase m48, ste24p
ALEK_1462	ENOG4107QPN	acyl-Coa dehydrogenase
ALEK_1463	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
ALEK_1465	ENOG4108IQE	Amp-dependent synthetase and ligase
ALEK_1466	ENOG4108UZ3	Transporter
ALEK_1468	ENOG4105C2N	RNA methyltransferase TrmH family group 3
ALEK_1469	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
ALEK_1470	ENOG4105C9Q	fumarate hydratase class II
ALEK_1473	ENOG4105C26	Dehydrogenase
ALEK_1480	ENOG4105EI2	Pseudouridine synthase
ALEK_1485	ENOG4105E3S	small subunit
ALEK_1486	ENOG4105DPX	Hydrogenase, large subunit
ALEK_1492	ENOG4105EUZ	Beta-lactamase domain protein
ALEK_1493	ENOG4105E3S	small subunit
ALEK_1494	ENOG4105DPX	Hydrogenase, large subunit
ALEK_1495	ENOG4105X7T	Ni Fe-hydrogenase, b-type cytochrome subunit
ALEK_1496	ENOG4108USZ	hydrogenase
ALEK_1497	ENOG4108P97	
ALEK_1500	ENOG4108RCM	Nitroreductase
ALEK_1507	ENOG4105C8J	)-transporter
ALEK_1508	ENOG41084TB	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
ALEK_1509	ENOG4107QMS	site-determining protein
ALEK_1510	ENOG4107YDG	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
ALEK_1511	ENOG4105C1J	atp-dependent rna helicase
ALEK_1514	ENOG4105CA0	peroxidase
ALEK_1515	ENOG4108IXY	short-chain dehydrogenase reductase
ALEK_1517	ENOG4105E1F	short-chain dehydrogenase reductase
ALEK_1519	ENOG4105VCH	membrane
ALEK_1521	ENOG4105BZU	Histidine kinase
ALEK_1524	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
ALEK_1529	ENOG4105C8Q	Methyl-accepting chemotaxis
ALEK_1530	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
ALEK_1531	ENOG4105WRB	Hydrogenase assembly chaperone hypC hupF
ALEK_1532	ENOG4105CQS	hydrogenase expression formation protein HypD
ALEK_1533	ENOG4105C45	hydrogenase expression formation protein (HypE)
ALEK_1534	ENOG4105F71	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
ALEK_1535	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
ALEK_1539	ENOG4105C32	Amino acid ABC transporter (Permease)
ALEK_1540	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
ALEK_1541	ENOG4105C0Z	ABC transporter
ALEK_1542	ENOG4108IV0	ABC, transporter
ALEK_1543	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
ALEK_1548	ENOG4105C25	Primosomal protein n'
ALEK_1550	ENOG4107QX8	SPFH domain, Band 7 family protein
ALEK_1551	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
ALEK_1553	ENOG4105C5H	ABC transporter
ALEK_1555	ENOG4105KPY	Small multidrug resistance protein
ALEK_1558	ENOG4106HK8	GPR1 FUN34 yaaH family protein
ALEK_1561	ENOG4105CAK	Cell division ATP-binding protein ftsE
ALEK_1562	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
ALEK_1564	ENOG4105C34	Pseudouridine synthase
ALEK_1565	ENOG4105CNI	cell division protein FtsW
ALEK_1566	ENOG4105CYW	agmatinase
ALEK_1570	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
ALEK_1571	ENOG4105NBK	UPF0345 protein
ALEK_1575	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
ALEK_1576	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
ALEK_1577	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
ALEK_1580	ENOG41067V7	50S ribosomal protein L36
ALEK_1581	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ALEK_1582	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
ALEK_1583	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
ALEK_1584	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
ALEK_1585	ENOG4108ZT0	50S ribosomal protein l17
ALEK_1586	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
ALEK_1587	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
ALEK_1596	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
ALEK_1601	ENOG4108YZY	peptidylprolyl cis-trans isomerase
ALEK_1602	ENOG4108URH	decarboxylase
ALEK_1605	ENOG4108YZY	peptidylprolyl cis-trans isomerase
ALEK_1607	ENOG4105CUC	YeeE YedE family protein
ALEK_1610	ENOG4105N14	lysine exporter protein LysE YggA
ALEK_1611	ENOG4105N14	lysine exporter protein LysE YggA
ALEK_1614	ENOG4105GAV	receptor
ALEK_1618	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
ALEK_1620	ENOG4105DWV	Homoserine O-trans-acetylase
ALEK_1622	ENOG4105D06	uba thif-type nad fad binding protein
ALEK_1623	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
ALEK_1628	ENOG4108JJA	ABC, transporter
ALEK_1638	ENOG4105D49	3-dehydroquinate synthase
ALEK_1640	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
ALEK_1641	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
ALEK_1643	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
ALEK_1644	ENOG4105C8P	)-transporter
ALEK_1645	ENOG4105C98	muts2 protein
ALEK_1649	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
ALEK_1652	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
ALEK_1653	ENOG4105KK4	UPF0060 membrane protein
ALEK_1656	ENOG4108BRW	Activates expression of the rhaSR operon in response to L-rhamnose (By similarity)
ALEK_1658	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
ALEK_1660	ENOG4105DKW	ABC transporter
ALEK_1664	ENOG4105T16	Transcriptional regulator (AraC family)
ALEK_1665	ENOG4108V1U	phospholipid-binding protein
ALEK_1669	ENOG4105BZU	Histidine kinase
ALEK_1672	ENOG4105DUM	transcriptional regulator, lysR family
ALEK_1673	ENOG4105HMI	Membrane
ALEK_1676	ENOG4105KVH	Transcriptional regulator
ALEK_1677	ENOG4105NF4	modulator of drug activity
ALEK_1679	ENOG4108RCM	Nitroreductase
ALEK_1681	ENOG4105WH1	Two component transcriptional regulator luxr family
ALEK_1684	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
ALEK_1685	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
ALEK_1689	ENOG4105E0C	molybdate abc transporter
ALEK_1691	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
ALEK_1692	ENOG4105F4R	Transcriptional regulator mode
ALEK_1696	ENOG4105GR3	Histidine kinase
ALEK_1698	ENOG41066UZ	arginase EC 3.5.3.1
ALEK_1700	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
ALEK_1703	ENOG4105BZU	Histidine kinase
ALEK_1704	ENOG4105BZU	Histidine kinase
ALEK_1705	ENOG4105C5H	ABC transporter
ALEK_1706	ENOG4108S4H	thioesterase Superfamily protein
ALEK_1708	ENOG4105BZU	Histidine kinase
ALEK_1709	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
ALEK_1711	ENOG4105BZU	Histidine kinase
ALEK_1719	ENOG4105CIN	aminoacyl-histidine dipeptidase
ALEK_1720	ENOG4105DHT	Metal Dependent Phosphohydrolase
ALEK_1728	ENOG4108STX	response regulator
ALEK_1729	ENOG4105BZU	Histidine kinase
ALEK_1732	ENOG4105EMU	Dehydrogenase
ALEK_1733	ENOG4105CRE	cytochrome C
ALEK_1734	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
ALEK_1736	ENOG4105BZU	Histidine kinase
ALEK_1737	ENOG4105C5X	domain protein
ALEK_1739	ENOG4107414	GntR family transcriptional regulator
ALEK_1740	ENOG4105D5T	phosphonate abc transporter
ALEK_1746	ENOG4105FT8	Phosphonate metabolism
ALEK_1747	ENOG4105ENV	phosphonate C-P lyase system protein PhnK
ALEK_1748	ENOG4105HRV	phosphonate c-p lyase system protein phnl
ALEK_1749	ENOG4105FD8	phosphonate metabolism protein PhnM
ALEK_1751	ENOG4105C8Q	Methyl-accepting chemotaxis
ALEK_1752	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
ALEK_1758	ENOG4105QNF	Outer membrane lipoprotein
ALEK_1761	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
ALEK_1764	ENOG4105QNF	Outer membrane lipoprotein
ALEK_1765	ENOG4105CT4	transporter
ALEK_1767	ENOG4107FW0	short-chain dehydrogenase reductase
ALEK_1771	ENOG4108JJA	ABC, transporter
ALEK_1775	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
ALEK_1776	ENOG4105BZU	Histidine kinase
ALEK_1777	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
ALEK_1778	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
ALEK_1779	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
ALEK_1780	ENOG4105C8Q	Methyl-accepting chemotaxis
ALEK_1783	ENOG4108Z0R	Transferase
ALEK_1786	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
ALEK_1788	ENOG4105CDH	Citrulline--aspartate ligase
ALEK_1790	ENOG4107S1N	anthranilate phosphoribosyltransferase
ALEK_1791	ENOG4105K8N	protein family UPF0079, ATPase
ALEK_1792	ENOG4108IUZ	ABC transporter
ALEK_1793	ENOG4105BZU	Histidine kinase
ALEK_1794	ENOG4105BZU	Histidine kinase
ALEK_1795	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
ALEK_1796	ENOG4105C2M	dna polymerase I
ALEK_1800	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
ALEK_1801	ENOG4105DF6	Fe-S oxidoreductase
ALEK_1802	ENOG4105D4P	Coproporphyrinogen iii oxidase
ALEK_1803	ENOG4105DBV	ornithine carbamoyltransferase
ALEK_1804	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
ALEK_1807	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
ALEK_1808	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
ALEK_1809	ENOG4105D52	delta-aminolevulinic acid dehydratase
ALEK_1811	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
ALEK_1827	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
ALEK_1828	ENOG4105D9Q	decarboxylase (Beta subunit)
ALEK_1833	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
ALEK_1835	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
ALEK_1837	ENOG4105RWS	endonuclease I
ALEK_1841	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
ALEK_1843	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
ALEK_1844	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ALEK_1846	ENOG4105EEI	dihydropteroate synthase
ALEK_1849	ENOG4105CFH	Aspartokinase
ALEK_1850	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
ALEK_1851	ENOG4105CSA	Coproporphyrinogen iii oxidase
ALEK_1852	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
ALEK_1853	ENOG4105DGW	oligopeptidase A
ALEK_1856	ENOG4108EU4	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
ALEK_1857	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
ALEK_1858	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
ALEK_1859	ENOG4105BZU	Histidine kinase
ALEK_1860	ENOG4105CBS	Chea signal transduction histidine kinase
ALEK_1861	ENOG4108VYJ	response regulator receiver protein
ALEK_1862	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
ALEK_1864	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
ALEK_1868	ENOG4105CHH	sulfate transporter
ALEK_1869	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
ALEK_1871	ENOG4105CNU	cell division protein FtsK
ALEK_1872	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
ALEK_1873	ENOG4108ZP8	Acetolactate synthase small subunit
ALEK_1874	ENOG4105C7K	acetolactate synthase
ALEK_1877	ENOG4108VTU	Cdp-alcohol phosphatidyltransferase
ALEK_1880	ENOG4105CHH	sulfate transporter
ALEK_1885	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
ALEK_1888	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
ALEK_1891	ENOG4105CGY	Dna recombination protein
ALEK_1892	ENOG4105C2Y	STE24 endopeptidase EC 3.4.24.84
ALEK_1893	ENOG4105BZU	Histidine kinase
ALEK_1895	ENOG4107YD3	Thioesterase
ALEK_1903	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
ALEK_1904	ENOG4108JQ5	ABC transporter
ALEK_1905	ENOG4107R73	Mate efflux family protein
ALEK_1907	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
ALEK_1908	ENOG4105C8Q	Methyl-accepting chemotaxis
ALEK_1909	ENOG4105CPC	Aldo Keto reductase
ALEK_1915	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
ALEK_1919	ENOG4105CX4	Precorrin-6y C5,15-methyltransferase
ALEK_1920	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
ALEK_1921	ENOG4108P62	biosynthesis protein (CbiG)
ALEK_1922	ENOG4105E4R	Precorrin-3B C17-methyltransferase
ALEK_1925	ENOG4105E7U	AraC family transcriptional regulator
ALEK_1927	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
ALEK_1929	ENOG4105BZU	Histidine kinase
ALEK_1933	ENOG4105F2W	methyltransferase
ALEK_1934	ENOG4108IU2	vtamin B12-transporter permease
ALEK_1935	ENOG4108JJB	ABC transporter
ALEK_1940	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
ALEK_1942	ENOG4107QX8	SPFH domain, Band 7 family protein
ALEK_1944	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
ALEK_1946	ENOG4105CIY	formyltetrahydrofolate deformylase
ALEK_1948	ENOG4105C26	Dehydrogenase
ALEK_1949	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
ALEK_1952	ENOG4105EB1	binding-protein-dependent transport systems inner membrane Component
ALEK_1955	ENOG4108IJ9	(ABC) transporter
ALEK_1956	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
ALEK_1958	ENOG4105FDP	GntR family transcriptional regulator
ALEK_1959	ENOG4105C6K	Malic enzyme
ALEK_1960	ENOG4108IJ0	Aspartate ammonia-lyase
ALEK_1961	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
ALEK_1962	ENOG4105BZU	Histidine kinase
ALEK_1963	ENOG4108RQS	Two component transcriptional regulator (Winged helix family
ALEK_1967	ENOG4105E2X	shikimate dehydrogenase
ALEK_1971	ENOG4105CEM	UPF0597 protein
ALEK_1972	ENOG4105EGI	Transcriptional regulator
ALEK_1974	ENOG4105CJW	magnesium transporter
ALEK_1976	ENOG4108UHV	Lipoprotein
ALEK_1977	ENOG4106032	Glutathionylspermidine synthase
ALEK_1984	ENOG4105EKT	)-iron permease
ALEK_1985	ENOG41088SP	formiminoglutamate hydrolase
ALEK_1986	ENOG4105CI2	imidazolone-5-propionate hydrolase
ALEK_1987	ENOG4105CGP	Urocanate hydratase
ALEK_1989	ENOG4105FDP	GntR family transcriptional regulator
ALEK_1996	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
ALEK_1998	ENOG4105C4K	Nad synthetase
ALEK_2002	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
ALEK_2004	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
ALEK_2005	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
ALEK_2011	ENOG4105C8J	)-transporter
ALEK_2015	ENOG4105BZW	Glycerate kinase
ALEK_2016	ENOG4105KIR	Thiol-disulfide oxidoreductase dcc
ALEK_2019	ENOG4105EYW	Ion transport protein
ALEK_2023	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
ALEK_2026	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
ALEK_2028	ENOG4105EBA	Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity)
ALEK_2036	ENOG4105XDF	Protein of unknown function (DUF1272)
ALEK_2038	ENOG4106MWK	domain protein
ALEK_2041	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
ALEK_2042	ENOG4105BZU	Histidine kinase
ALEK_2043	ENOG4107QUV	Domain protein
ALEK_2044	ENOG4108M3P	Membrane
ALEK_2045	ENOG4108K0D	peptidase, M48
ALEK_2046	ENOG4105EYH	Exonuclease
ALEK_2048	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
ALEK_2050	ENOG4108HGU	Histidine kinase
ALEK_2051	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
ALEK_2057	ENOG4105E46	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process
ALEK_2060	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
ALEK_2061	ENOG4107XM9	(LipO)protein
ALEK_2064	ENOG4105BZU	Histidine kinase
ALEK_2066	ENOG4105DJI	Methylaspartate mutase, E subunit
ALEK_2068	ENOG4105CEY	Amp-dependent synthetase and ligase
ALEK_2074	ENOG4105F0I	Aminotransferase
ALEK_2078	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
ALEK_2080	ENOG410841J	DNA-binding protein Hu
ALEK_2083	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
ALEK_2085	ENOG4105DY9	regulatoR
ALEK_2086	ENOG4108HRK	Histidine kinase
ALEK_2087	ENOG4105EWK	phytoene
ALEK_2088	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
ALEK_2089	ENOG4107SEY	Conserved Protein
ALEK_2090	ENOG4105CQ7	ATP-dependent helicase
ALEK_2096	ENOG4105ID8	Transcriptional regulator, ARAC family
ALEK_2098	ENOG4105I03	Flagellin
ALEK_2098	ENOG4105I03	Flagellin
ALEK_2107	ENOG4105C8Q	Methyl-accepting chemotaxis
ALEK_2108	ENOG4105BZ1	(ABC) transporter
ALEK_2110	ENOG4105DSF	transport protein
ALEK_2113	ENOG410829K	Lysine exporter protein (Lyse ygga)
ALEK_2115	ENOG4105ZGC	lipoprotein carrier protein
ALEK_2116	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
ALEK_2117	ENOG4105D60	lipoprotein releasing system transmembrane protein
ALEK_2118	ENOG4105BZU	Histidine kinase
ALEK_2120	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
ALEK_2123	ENOG4105E9K	Isocitrate dehydrogenase
ALEK_2124	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
ALEK_2126	ENOG4105PGM	cation diffusion facilitator family transporter
ALEK_2129	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
ALEK_2131	ENOG4105DVC	DnaJ domain protein
ALEK_2132	ENOG4105KNI	merR family transcriptional Regulator
ALEK_2133	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
ALEK_2134	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
ALEK_2136	ENOG4105C7H	Helicase, RecD TraA family
ALEK_2141	ENOG4105ERG	peptidase m48, ste24p
ALEK_2145	ENOG4105CJN	penicillin-binding protein
ALEK_2147	ENOG4105HKU	nucleoside recognition domain-containing protein
ALEK_2148	ENOG4105CN7	Flagellar biosynthetic protein FliP
ALEK_2149	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
ALEK_2153	ENOG4105BZS	acriflavin resistance protein
ALEK_2154	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
ALEK_2155	ENOG4105EB3	Histidine kinase
ALEK_2156	ENOG4105DEF	Extracellular solute-binding protein, family 5
ALEK_2157	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
ALEK_2158	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
ALEK_2160	ENOG4108JQ7	(ABC) transporter
ALEK_2161	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
ALEK_2165	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
ALEK_2168	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
ALEK_2169	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
ALEK_2170	ENOG4105K6T	rare lipoprotein A
ALEK_2171	ENOG4105F8V	Hydrolase, tatD family
ALEK_2173	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
ALEK_2174	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
ALEK_2175	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
ALEK_2180	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
ALEK_2181	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
ALEK_2182	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
ALEK_2183	ENOG4105CUT	histidyl-tRNA synthetase
ALEK_2184	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
ALEK_2185	ENOG4105D7W	serine acetyltransferase
ALEK_2188	ENOG4108I0Z	Aconitate hydratase
ALEK_2192	ENOG4105CH6	catalase
ALEK_2193	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
ALEK_2197	ENOG4108JU6	CBS domain protein
ALEK_2198	ENOG4108UHE	carbonic anhydrase
ALEK_2199	ENOG4105PYN	Pyridoxamine 5-phosphate oxidase-related
ALEK_2202	ENOG4105DSF	transport protein
ALEK_2206	ENOG4108VPC	n-acetylmuramoyl-l-alanine amidase
ALEK_2208	ENOG4105BZU	Histidine kinase
ALEK_2209	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
ALEK_2210	ENOG4105VIG	Sec-independent protein translocase protein TatC
ALEK_2213	ENOG4105CTQ	phosphohexokinase
ALEK_2214	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
ALEK_2215	ENOG4105DR4	Methyltransferase
ALEK_2216	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
ALEK_2217	ENOG4105BZU	Histidine kinase
ALEK_2219	ENOG4108MRH	transcriptional regulatory protein
ALEK_2221	ENOG4107QN2	dihydrolipoyl dehydrogenase
ALEK_2223	ENOG4105W4W	Transcriptional regulator
ALEK_2224	ENOG4105UEI	Transcriptional Regulator AraC Family
ALEK_2225	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
ALEK_2228	ENOG4105PW4	Sugar fermentation stimulation protein homolog
ALEK_2231	ENOG4105W4W	Transcriptional regulator
ALEK_2242	ENOG4105M4H	endoribonuclease L-psp
ALEK_2243	ENOG4105EN6	Membrane
ALEK_2244	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
ALEK_2245	ENOG4105BZU	Histidine kinase
ALEK_2247	ENOG4105BZU	Histidine kinase
ALEK_2252	ENOG4105KQ5	peptidylprolyl cis-trans isomerase
ALEK_2254	ENOG4108VKQ	nitriC oxide reductase
ALEK_2257	ENOG4105GMT	ATPase associated with various cellular activities aaa_5
ALEK_2258	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
ALEK_2262	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
ALEK_2268	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
ALEK_2270	ENOG4105CF7	AraC family transcriptional regulator
ALEK_2271	ENOG4105NF4	modulator of drug activity
ALEK_2273	ENOG4105C5I	Dehydrogenase
ALEK_2274	ENOG4105CTD	carboxy-peptidase
ALEK_2287	ENOG4105D5K	Hemolysin activator protein
ALEK_2288	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
ALEK_2289	ENOG4105BZU	Histidine kinase
ALEK_2290	ENOG4107VQW	regulatoR
ALEK_2300	ENOG4105VCQ	rubredoxin
ALEK_2304	ENOG4105FE9	pseudouridine synthase
ALEK_2312	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
ALEK_2316	ENOG4105M4H	endoribonuclease L-psp
ALEK_2320	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
ALEK_2322	ENOG4105DN9	Na H antiporter
ALEK_2323	ENOG4108IYU	L-aspartate oxidase
ALEK_2326	ENOG4108VKG	metal-dependent hydrolase
ALEK_2328	ENOG41076HS	cation diffusion facilitator family transporter
ALEK_2329	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
ALEK_2331	ENOG4105F8J	Adenylate Guanylate cyclase
ALEK_2337	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
ALEK_2338	ENOG4105BZU	Histidine kinase
ALEK_2341	ENOG4105D3Q	Sugar transferase
ALEK_2342	ENOG4108TJN	glycosyl transferase group 1
ALEK_2344	ENOG4108KBE	Glycosyl transferase, family 2
ALEK_2347	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
ALEK_2350	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
ALEK_2359	ENOG4105D7W	serine acetyltransferase
ALEK_2365	ENOG4105C5H	ABC transporter
ALEK_2366	ENOG4105KTH	gatB Yqey
ALEK_2367	ENOG4105BZU	Histidine kinase
ALEK_2370	ENOG4105DHT	Metal Dependent Phosphohydrolase
ALEK_2378	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
ALEK_2380	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
ALEK_2382	ENOG41080BE	Methyl-accepting chemotaxis sensory transducer
ALEK_2385	ENOG4108ERU	trap dicarboxylate transporter subunit DctP
ALEK_2387	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
ALEK_2391	ENOG4105ES5	Histidine kinase
ALEK_2397	ENOG4105ETX	regulatoR
ALEK_2398	ENOG4105DHQ	Histidine kinase
ALEK_2400	ENOG4105C5H	ABC transporter
ALEK_2403	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
ALEK_2405	ENOG4105CX6	glutaminyL-tRNA synthetase
ALEK_2406	ENOG4105CA0	peroxidase
ALEK_2407	ENOG4105BZU	Histidine kinase
ALEK_2408	ENOG4105JAB	phenazine biosynthesis protein, phzf family
ALEK_2409	ENOG41075H3	AraC family transcriptional regulator
ALEK_2417	ENOG4105E1F	short-chain dehydrogenase reductase
ALEK_2418	ENOG4107S6Z	Na H antiporter
ALEK_2421	ENOG4107VQW	regulatoR
ALEK_2423	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
ALEK_2424	ENOG4105EFX	secretion protein, HlyD family
ALEK_2425	ENOG4105KK7	inner membrane protein YiaW
ALEK_2427	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
ALEK_2428	ENOG4106H78	methyltransferase
ALEK_2430	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
ALEK_2432	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ALEK_2433	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
ALEK_2434	ENOG4105N14	lysine exporter protein LysE YggA
ALEK_2436	ENOG4108WZ2	response regulator
ALEK_2437	ENOG4105GR3	Histidine kinase
ALEK_2438	ENOG4105NQN	cytochrome C
ALEK_2439	ENOG4105IPS	esterase
ALEK_2441	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
ALEK_2443	ENOG41080V7	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
ALEK_2446	ENOG4108RAC	Rubrerythrin
ALEK_2447	ENOG4108RAC	Rubrerythrin
ALEK_2449	ENOG4105CJR	Integral membrane protein (MviN
ALEK_2451	ENOG4105BZ9	Cytochrome C oxidase, subunit I
ALEK_2452	ENOG4105CCU	oxidase (Subunit III)
ALEK_2454	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
ALEK_2456	ENOG4105BZ1	(ABC) transporter
ALEK_2457	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
ALEK_2460	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
ALEK_2461	ENOG4105CAN	Short-chain dehydrogenase reductase Sdr
ALEK_2462	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
ALEK_2463	ENOG4105DZP	Membrane-associated zinc metalloprotease
ALEK_2464	ENOG4105DFA	alanine racemase domain protein
ALEK_2465	ENOG4105VSH	4-oxalocrotonate tautomerase
ALEK_2469	ENOG4105BZU	Histidine kinase
ALEK_2470	ENOG4105DK0	Indole-3-glycerol phosphate synthase
ALEK_2472	ENOG4105QTX	Pfam:UPF0153
ALEK_2473	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
ALEK_2475	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
ALEK_2476	ENOG4105DQU	oxidoreductase, subunit beta
ALEK_2478	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
ALEK_2479	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
ALEK_2480	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
ALEK_2481	ENOG4105DJV	ribulose-phosphate 3-epimerase
ALEK_2482	ENOG4105HDD	phospholipase
ALEK_2484	ENOG4107VIJ	nudix hydrolase
ALEK_2488	ENOG4108VPT	UPF0234 protein
ALEK_2489	ENOG4105C2W	permease
ALEK_2490	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
ALEK_2493	ENOG4105M08	Membrane
ALEK_2495	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
ALEK_2496	ENOG4105C7N	Xanthine uracil vitamin C permease
ALEK_2499	ENOG4105VG1	fes assembly suf system protein
ALEK_2500	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
ALEK_2501	ENOG4105EQD	regulatoR
ALEK_2515	ENOG41082XB	radical SAM domain protein
ALEK_2516	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
ALEK_2518	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
ALEK_2521	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
ALEK_2522	ENOG4107SVH	Potassium channel protein
ALEK_2523	ENOG4105VB9	50S ribosomal protein l28
ALEK_2526	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
ALEK_2528	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
ALEK_2529	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
ALEK_2530	ENOG4105DKP	glycosyl transferase, family 9
ALEK_2531	ENOG4107UU3	sucrose-phosphate synthase (EC 2.4.1.14)
ALEK_2533	ENOG4105M5K	heptosyltransferase
ALEK_2534	ENOG4105D16	lipopolysaccharide heptosyltransferase i
ALEK_2535	ENOG4105CPK	Glycosyl transferase (Group 1
ALEK_2540	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
ALEK_2541	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
ALEK_2543	ENOG4106WTF	Glycosyl transferase, family 2
ALEK_2545	ENOG4105D16	lipopolysaccharide heptosyltransferase i
ALEK_2547	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
ALEK_2548	ENOG4105ECY	inositol monophosphatase
ALEK_2549	ENOG4105BZ8	glutamate synthase
ALEK_2550	ENOG4105CBC	glutamate synthase
ALEK_2551	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
ALEK_2552	ENOG4108RA0	tripartite ATP-independent periplasmic transporter, DctQ component
ALEK_2553	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
ALEK_2557	ENOG4108UJV	acyl-CoA thioesterase i
ALEK_2558	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
ALEK_2565	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
ALEK_2585	ENOG4105WH1	Two component transcriptional regulator luxr family
ALEK_2596	ENOG4105CQZ	Histidine kinase
ALEK_2597	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
ALEK_2615	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
ALEK_2616	ENOG4105M7K	Involved in the transcription termination process (By similarity)
ALEK_2617	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
ALEK_2618	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
ALEK_2621	ENOG4105CBC	glutamate synthase
ALEK_2623	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
ALEK_2629	ENOG4107QHF	type ii secretion system protein e
ALEK_2630	ENOG4105GVR	general secretion pathway protein D
ALEK_2638	ENOG4108VAU	general secretion pathway protein G
ALEK_2639	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
ALEK_2640	ENOG4105DX0	Hemolysin A
ALEK_2642	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
ALEK_2643	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ALEK_2645	ENOG4105CQB	FAD linked oxidase domain protein
ALEK_2654	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
ALEK_2655	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
ALEK_2656	ENOG4108YZY	peptidylprolyl cis-trans isomerase
ALEK_2659	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
ALEK_2661	ENOG4105M8F	Biopolymer transport protein exbD tolR
ALEK_2662	ENOG4105E02	MotA TolQ exbB proton channel
ALEK_2663	ENOG41082MC	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
ALEK_2664	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
ALEK_2665	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
ALEK_2666	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
ALEK_2667	ENOG4105PQH	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
ALEK_2668	ENOG4105YF2	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
ALEK_2670	ENOG4105FA0	parb-like partition protein
ALEK_2671	ENOG4107QJE	Chromosome Partitioning Protein
ALEK_2674	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
ALEK_2675	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
ALEK_2676	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ALEK_2677	ENOG4105K46	50S ribosomal protein l27
ALEK_2678	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
ALEK_2679	ENOG4105KME	endoribonuclease L-psp
ALEK_2680	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
ALEK_2682	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
ALEK_2683	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
ALEK_2684	ENOG4105D0M	Protease HtpX homolog
ALEK_2685	ENOG4107RPC	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
ALEK_2688	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
ALEK_2690	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
ALEK_2691	ENOG4108512	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
ALEK_2692	ENOG4105VG0	50S ribosomal protein l34
ALEK_2694	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
ALEK_2698	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
ALEK_2701	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
ALEK_2702	ENOG4105E0X	reductase
ALEK_2703	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
ALEK_2704	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
ALEK_2705	ENOG4105BZU	Histidine kinase
ALEK_2706	ENOG4105CBC	glutamate synthase
ALEK_2707	ENOG4109045	doxx family
ALEK_2708	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
ALEK_2710	ENOG4109045	doxx family
ALEK_2713	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
ALEK_2719	ENOG4105DC1	bifunctional purine biosynthesis protein purh
ALEK_2725	ENOG4108BGM	Quinol dehydrogenase periplasmic component
ALEK_2727	ENOG4106RE7	Cytochrome
ALEK_2729	ENOG4108M15	ABC transporter
ALEK_2731	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
ALEK_2732	ENOG4105DR5	peptidase
ALEK_2733	ENOG4105CJW	magnesium transporter
ALEK_2735	ENOG4105EUJ	GTP cyclohydrolase i
ALEK_2737	ENOG4107QHF	type ii secretion system protein e
ALEK_2740	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
ALEK_2741	ENOG4105C0P	Mg chelatase subunit ChlI
ALEK_2742	ENOG4105C8Q	Methyl-accepting chemotaxis
ALEK_2743	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
ALEK_2745	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
ALEK_2746	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
ALEK_2747	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
ALEK_2748	ENOG4107QVM	von Willebrand factor, type A
ALEK_2749	ENOG4105CSR	polyphosphate kinase 2
ALEK_2750	ENOG4105CSR	polyphosphate kinase 2
ALEK_2752	ENOG4105VCQ	rubredoxin
ALEK_2766	ENOG4105C8Q	Methyl-accepting chemotaxis
ALEK_2767	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
ALEK_2775	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
ALEK_2786	ENOG4105CE1	Ferrous iron transport protein b
ALEK_2793	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
ALEK_2795	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
ALEK_2796	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
ALEK_2797	ENOG4105F4G	Membrane
ALEK_2800	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
ALEK_2803	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
ALEK_2806	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
ALEK_2808	ENOG4105I03	Flagellin
ALEK_2809	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
ALEK_2810	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
ALEK_2811	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
ALEK_2813	ENOG4105CEY	Amp-dependent synthetase and ligase
ALEK_2814	ENOG4105DJG	MaoC domain protein dehydratase
ALEK_2823	ENOG4105C8Q	Methyl-accepting chemotaxis
ALEK_2825	ENOG4107XC4	flavin reductase domain protein, FMN-binding
ALEK_2832	ENOG4105D7B	Flagellar biosynthesis protein flha
ALEK_2833	ENOG4105DTJ	flagellar hook-associated protein
ALEK_2834	ENOG4108JIR	Flagellum-specific ATP synthase
ALEK_2836	ENOG4105D00	flagellar biosynthetic protein flhB
ALEK_2839	ENOG4108ZC9	flagellar basal-body rod protein flgc
ALEK_2840	ENOG41084DA	flagellar hook-basal body complex protein fliE
ALEK_2842	ENOG4107R21	site-determining protein
ALEK_2843	ENOG4105FZW	flagellar biosynthesis regulator FlhF
ALEK_2846	ENOG4105YKR	
ALEK_2848	ENOG4105E14	MotA TolQ exbB proton channel
ALEK_2849	ENOG4105DD5	Flagellar motor switch protein
ALEK_2853	ENOG4105BZE	flagellar hook protein, FlgE
ALEK_2854	ENOG4105BZE	flagellar hook protein, FlgE
ALEK_2858	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
ALEK_2859	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
ALEK_2860	ENOG4105Q75	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
ALEK_2861	ENOG4105CGA	flagellar basal-body rod protein FlgG
ALEK_2863	ENOG4108VYJ	response regulator receiver protein
ALEK_2864	ENOG4105CGA	flagellar basal-body rod protein FlgG
ALEK_2867	ENOG4105V3S	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
ALEK_2869	ENOG4105K5M	30s ribosomal protein S16
ALEK_2870	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ALEK_2871	ENOG4105C34	Pseudouridine synthase
ALEK_2872	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
ALEK_2874	ENOG4105EGD	dinuclear metal center protein, YbgI family
ALEK_2875	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
ALEK_2876	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
ALEK_2878	ENOG4105CFP	Peptidase U32
ALEK_2887	ENOG4105QN4	diheme cytochrome
ALEK_2892	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
ALEK_2893	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
ALEK_2894	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
ALEK_2895	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
ALEK_2896	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
ALEK_2897	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
ALEK_2899	ENOG4105DUM	transcriptional regulator, lysR family
ALEK_2901	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
ALEK_2903	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
ALEK_2904	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
ALEK_2905	ENOG4105KME	endoribonuclease L-psp
ALEK_2906	ENOG4105HMI	Membrane
ALEK_2907	ENOG4108UPT	UPF0178 protein
ALEK_2911	ENOG4107R4J	Chloride channel
ALEK_2913	ENOG4105C8Q	Methyl-accepting chemotaxis
ALEK_2916	ENOG4105BZU	Histidine kinase
ALEK_2918	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
ALEK_2919	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
ALEK_2921	ENOG4108VZM	50s ribosomal protein L10
ALEK_2922	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
ALEK_2923	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
ALEK_2924	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
ALEK_2927	ENOG41086AR	50S ribosomal protein L33
ALEK_2928	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
ALEK_2934	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
ALEK_2935	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
ALEK_2937	ENOG4108JQC	penicillin-binding protein 1A
ALEK_2938	ENOG4105C5F	glutamine synthetase
ALEK_2940	ENOG4108ZEX	molybdopterin converting factor, subunit 2
ALEK_2942	ENOG4108XUR	Pfam:DUF178
ALEK_2943	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
ALEK_2945	ENOG4105CNI	cell division protein FtsW
ALEK_2946	ENOG4105CJN	penicillin-binding protein
ALEK_2947	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
ALEK_2957	ENOG4105DDQ	anthranilate synthase
ALEK_2961	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
ALEK_2962	ENOG4105BZU	Histidine kinase
ALEK_2963	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
ALEK_2964	ENOG4105C87	Aminotransferase class I and II
ALEK_2965	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
ALEK_2966	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
ALEK_2967	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
ALEK_2968	ENOG4105GKE	subunit e
ALEK_2970	ENOG4105BZN	citrate synthase
ALEK_2971	ENOG4108IEH	NADH dehydrogenase subunit g
ALEK_2972	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
ALEK_2974	ENOG4107UFS	subunit j
ALEK_2975	ENOG41080EA	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
ALEK_2976	ENOG4105D65	subunit l
ALEK_2977	ENOG4105C8S	subunit m
ALEK_2978	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
ALEK_2979	ENOG4108S24	Fumarate reduCtase
ALEK_2980	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
ALEK_2981	ENOG4105E33	succinate dehydrogenase
ALEK_2984	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
ALEK_2985	ENOG4108VKG	metal-dependent hydrolase
ALEK_2997	ENOG41081FY	multiple antibiotic resistance (MarC)-related
ALEK_2998	ENOG4105E5Q	amino acid AbC transporter
ALEK_2999	ENOG4106PMH	Extracellular solute-binding protein family 3
ALEK_3000	ENOG4106PMH	Extracellular solute-binding protein family 3
ALEK_3004	ENOG4108BSC	Methyltransferase
ALEK_3005	ENOG4105YVS	arsR family transcriptional regulator
ALEK_3007	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
ALEK_3008	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
ALEK_3014	ENOG4105C9U	ATP-dependent DNA helicase RecQ
ALEK_3016	ENOG4105C5I	Dehydrogenase
ALEK_3021	ENOG4105CR4	methylisocitrate lyase
ALEK_3022	ENOG4105BZN	citrate synthase
ALEK_3023	ENOG4108I0Z	Aconitate hydratase
ALEK_3024	ENOG4105C7F	AcnD-accessory protein PrpF
ALEK_3025	ENOG410620I	Diguanylate cyclase
ALEK_3027	ENOG4108QGH	periplasmic
ALEK_3029	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
ALEK_3032	ENOG4107QMP	dna polymerase iii subunits gamma and tau
ALEK_3033	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
ALEK_3036	ENOG4105D01	(LipO)protein
ALEK_3037	ENOG4108UMI	ABC transporter, permease
ALEK_3038	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
ALEK_3039	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
ALEK_3040	ENOG4105D3R	alkyl hydroperoxide reductase
ALEK_3042	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
ALEK_3044	ENOG4105YQ2	50s ribosomal protein l32
ALEK_3045	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
ALEK_3046	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
ALEK_3048	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
ALEK_3049	ENOG4108YYC	ycei family
ALEK_3052	ENOG4108UMN	azlc family
ALEK_3058	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
ALEK_3061	ENOG4105CXT	aspartate transcarbamylase
ALEK_3063	ENOG4105C8Y	Acetylornithine aminotransferase
ALEK_3065	ENOG4105BZU	Histidine kinase
ALEK_3071	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
ALEK_3072	ENOG41082UM	UPF0102 protein
ALEK_3073	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
ALEK_3075	ENOG4106AXJ	AraC family transcriptional regulator
ALEK_3076	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
ALEK_3080	ENOG4105DVY	radical SAM domain protein
ALEK_3082	ENOG4105KB8	(LipO)protein
ALEK_3083	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
ALEK_3085	ENOG4105CHV	Transcription elongation factor NusA
ALEK_3086	ENOG4105C8N	cysteinyl-tRNA synthetase
ALEK_3089	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
ALEK_3090	ENOG4108UUM	single-stranded DNA-binding protein
ALEK_3091	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
ALEK_3093	ENOG410821Z	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum (By similarity)
ALEK_3096	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
ALEK_3099	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
ALEK_3103	ENOG4106AXJ	AraC family transcriptional regulator
ALEK_3104	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
ALEK_3105	ENOG4105DFU	Cell wall formation (By similarity)
ALEK_3107	ENOG4105CHM	Aminotransferase
ALEK_3111	ENOG4105BZU	Histidine kinase
ALEK_3112	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
ALEK_3118	ENOG4108EHY	type IV secretion system
ALEK_3125	ENOG410855J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
ALEK_3126	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
ALEK_3128	ENOG4105EAC	phosphoserine phosphatase
ALEK_3129	ENOG4105GSH	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
ALEK_3131	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
ALEK_3132	ENOG410829W	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
ALEK_3134	ENOG4107R03	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
ALEK_3136	ENOG4108YYC	ycei family
ALEK_3137	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
ALEK_3141	ENOG4107TPX	flagellar hook-associated
ALEK_3148	ENOG4105VS8	Flagellar biosynthetic protein fliq
ALEK_3150	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
ALEK_3151	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
ALEK_3152	ENOG4105EKE	dihydroorotase
ALEK_3153	ENOG4108YZA	Nitrogen regulatory protein pii
ALEK_3155	ENOG4108YZA	Nitrogen regulatory protein pii
ALEK_3157	ENOG4105C8Q	Methyl-accepting chemotaxis
ALEK_3158	ENOG4107XTP	(EAL) domain protein
ALEK_3159	ENOG4105D7T	ABC transporter
ALEK_3163	ENOG4105D9P	serine threonine protein kinase
ALEK_3166	ENOG4108XIB	electron transport protein ysaA
ALEK_3172	ENOG41067MG	lrgb family
ALEK_3173	ENOG4105VAW	lrga family
ALEK_3174	ENOG4108IFG	nitrite reductase, (NAD(P)H)
ALEK_3181	ENOG4105CEY	Amp-dependent synthetase and ligase
ALEK_3183	ENOG4105FR1	rard protein
ALEK_3184	ENOG4105BZU	Histidine kinase
ALEK_3187	ENOG4108UXE	Protein tyrosine phosphatase
ALEK_3188	ENOG4108MGY	Histidine kinase
ALEK_3189	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
ALEK_3190	ENOG4107R5R	arsenical pump membrane protein
ALEK_3192	ENOG41085FC	arsR family transcriptional regulator
ALEK_3193	ENOG4108RPX	mosc domain containing protein
ALEK_3194	ENOG41067MG	lrgb family
ALEK_3196	ENOG4108SGR	YheO domain-containing protein
ALEK_3198	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
ALEK_3201	ENOG4105CV1	Transketolase (EC 2.2.1.1)
ALEK_3202	ENOG4105BZU	Histidine kinase
ALEK_3205	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
ALEK_3208	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
ALEK_3215	ENOG4105C01	Dihydroxy-acid dehydratase
ALEK_3216	ENOG4105C0H	protease
ALEK_3220	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
ALEK_3221	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
ALEK_3222	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
ALEK_3227	ENOG4105BZU	Histidine kinase
ALEK_3229	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
ALEK_3232	ENOG41081FY	multiple antibiotic resistance (MarC)-related
ALEK_3233	ENOG4108K7V	UPF0284 protein
ALEK_3235	ENOG4105K63	Thioredoxin
ALEK_3236	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
ALEK_3238	ENOG4105BZU	Histidine kinase
ALEK_3239	ENOG4105DJ4	phosphatidylserine decarboxylase
ALEK_3241	ENOG4105CA3	membrane-bound lytic murein transglycosylase
ALEK_3243	ENOG4105CFG	Acts as a chaperone (By similarity)
ALEK_3244	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ALEK_3246	ENOG4105H1G	trap transporter solute receptor taxi family
ALEK_3248	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
ALEK_3250	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
ALEK_3252	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
ALEK_3253	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
ALEK_3255	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
ALEK_3257	ENOG4105C1J	atp-dependent rna helicase
ALEK_3258	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
ALEK_3259	ENOG4105I03	Flagellin
ALEK_3260	ENOG4105I03	Flagellin
ALEK_3261	ENOG4105I03	Flagellin
ALEK_3262	ENOG4105I03	Flagellin
ALEK_3263	ENOG4105I03	Flagellin
ALEK_3264	ENOG4105I03	Flagellin
ALEK_3265	ENOG4105I03	Flagellin
ALEK_3266	ENOG4105I03	Flagellin
ALEK_3267	ENOG4105I03	Flagellin
ALEK_3268	ENOG4105I03	Flagellin
ALEK_3269	ENOG4105I03	Flagellin
ALEK_3270	ENOG4105I03	Flagellin
ALEK_3276	ENOG4107TY6	Acylneuraminate cytidylyltransferase
ALEK_3278	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
ALEK_3280	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
ALEK_3282	ENOG4105D2T	synthase
ALEK_3284	ENOG4105C5E	polysaccharide biosynthesis protein
ALEK_3286	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
ALEK_3287	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
ALEK_3291	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
ALEK_3294	ENOG4105D4A	Cell wall formation (By similarity)
ALEK_3295	ENOG4105E63	Pfam:DUF178
ALEK_3297	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
ALEK_3298	ENOG4105C8S	subunit m
ALEK_3299	ENOG4105D65	subunit l
ALEK_3300	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
ALEK_3302	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
ALEK_3303	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
ALEK_3304	ENOG4108IEH	NADH dehydrogenase subunit g
ALEK_3307	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
ALEK_3308	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
ALEK_3309	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
ALEK_3310	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
ALEK_3311	ENOG4105C8Q	Methyl-accepting chemotaxis
ALEK_3320	ENOG4105DZR	Type I site-specific deoxyribonuclease
ALEK_3329	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
ALEK_3331	ENOG4105BZU	Histidine kinase
ALEK_3332	ENOG4108PYU	two-component system response regulator
ALEK_3335	ENOG4105BZU	Histidine kinase
ALEK_3338	ENOG4105WPN	DNA integration recombination invertion protein
ALEK_3339	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
ALEK_3340	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
ALEK_3341	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
ALEK_3342	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
ALEK_3346	ENOG4105C8Q	Methyl-accepting chemotaxis
ALEK_3347	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
ALEK_3349	ENOG4105C58	cytochrome c oxidase accessory protein ccog
ALEK_3350	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
ALEK_3351	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
ALEK_3356	ENOG4105F8J	Adenylate Guanylate cyclase
ALEK_3359	ENOG4105C0B	DNA polymerase III (alpha subunit)
ALEK_3360	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
ALEK_3365	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
ALEK_3376	ENOG4105HFZ	Membrane
ALEK_3377	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
ALEK_3379	ENOG4105NU9	Preprotein translocase subunit SecG
ALEK_3381	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
ALEK_3382	ENOG4107VCP	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
ALEK_3384	ENOG4105D8G	Major Facilitator superfamily
ALEK_3385	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
ALEK_3386	ENOG4105BZU	Histidine kinase
ALEK_3387	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
ALEK_3388	ENOG410802Z	Protein of unknown function (DUF328)
ALEK_3395	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
ALEK_3396	ENOG4105C26	Dehydrogenase
ALEK_3397	ENOG4105C7K	acetolactate synthase
ALEK_3398	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
ALEK_3409	ENOG4105CBX	hi0933 family
ALEK_3410	ENOG4108RPX	mosc domain containing protein
ALEK_3416	ENOG4105C6T	cysteine synthase
ALEK_3418	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
ALEK_3419	ENOG4105C11	sulfate adenylyltransferase), subunit 2
ALEK_3420	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
ALEK_3421	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
ALEK_3423	ENOG4105DIN	metallophosphoesterase
ALEK_3425	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
ALEK_3426	ENOG4105CI3	gtp-binding protein typa
ALEK_3427	ENOG4105CSV	Glutaminase
ALEK_3429	ENOG4105GAV	receptor
ALEK_3431	ENOG4105EMN	RNA polymerase sigma factor
ALEK_3433	ENOG4105EN6	Membrane
ALEK_3436	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
ALEK_3437	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)