locus-tag	class	description
Arnit_0001	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
Arnit_0002	COG0592	DNA-directed DNA polymerase activity
Arnit_0003	COG0187	DNA topoisomerase II activity
Arnit_0004	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
Arnit_0006	COG1451	nucleotide metabolic process
Arnit_0008	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
Arnit_0010	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Arnit_0011	COG1012	belongs to the aldehyde dehydrogenase family
Arnit_0013	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Arnit_0019	COG0492	ferredoxin-NADP+ reductase activity
Arnit_0020	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
Arnit_0023	COG1238	metal cluster binding
Arnit_0025	COG4191	Histidine kinase
Arnit_0026	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
Arnit_0028	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
Arnit_0033	COG1053	succinate dehydrogenase
Arnit_0034	COG0667	Aldo Keto reductase
Arnit_0035	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
Arnit_0036	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
Arnit_0039	COG4208	sulfate ABC transporter
Arnit_0047	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
Arnit_0049	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
Arnit_0050	COG0569	domain protein
Arnit_0051	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Arnit_0052	COG0745	RESPONSE REGULATOR receiver
Arnit_0053	COG2205	protein histidine kinase activity
Arnit_0055	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
Arnit_0060	COG0716	FMN binding
Arnit_0066	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
Arnit_0071	COG0628	permease
Arnit_0077	COG0426	domain, Protein
Arnit_0082	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Arnit_0088	COG0564	pseudouridine synthase activity
Arnit_0089	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
Arnit_0090	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Arnit_0091	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Arnit_0093	COG3706	GGDEF domain
Arnit_0096	COG0697	spore germination
Arnit_0102	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Arnit_0103	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Arnit_0105	COG1280	lysine exporter protein (LysE YggA)
Arnit_0110	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
Arnit_0112	COG0604	alcohol dehydrogenase
Arnit_0114	COG1733	regulation of RNA biosynthetic process
Arnit_0115	COG0390	transport system, permease component
Arnit_0116	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
Arnit_0118	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Arnit_0124	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
Arnit_0126	COG3852	Histidine kinase
Arnit_0127	COG1556	Lactate utilization protein
Arnit_0128	COG1139	Iron-sulfur cluster binding protein
Arnit_0129	COG0247	lactate metabolic process
Arnit_0131	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Arnit_0131	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Arnit_0132	COG0511	ligase activity, forming carbon-carbon bonds
Arnit_0133	COG0439	Biotin carboxylase
Arnit_0134	COG0513	Belongs to the DEAD box helicase family
Arnit_0136	COG0306	phosphate transporter
Arnit_0138	COG0367	asparagine synthase
Arnit_0141	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
Arnit_0142	COG1053	succinate dehydrogenase
Arnit_0144	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Arnit_0145	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
Arnit_0147	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
Arnit_0147	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
Arnit_0148	COG1187	pseudouridine synthase activity
Arnit_0149	COG0517	IMP dehydrogenase activity
Arnit_0149	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
Arnit_0150	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
Arnit_0151	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
Arnit_0152	COG0107	imidazoleglycerol-phosphate synthase activity
Arnit_0155	COG0820	rRNA (adenine-C2-)-methyltransferase activity
Arnit_0156	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Arnit_0158	COG2217	Heavy metal translocating P-type atpase
Arnit_0164	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Arnit_0167	COG0460	homoserine dehydrogenase
Arnit_0168	COG0436	Aminotransferase
Arnit_0171	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
Arnit_0172	COG0254	rRNA binding
Arnit_0173	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
Arnit_0174	COG3153	acetyltransferase
Arnit_0174	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Arnit_0175	COG0109	protoheme IX farnesyltransferase activity
Arnit_0190	COG2856	Zn peptidase
Arnit_0196	COG0515	serine threonine protein kinase
Arnit_0196	COG2815	serine threonine protein kinase
Arnit_0198	COG0631	protein serine/threonine phosphatase activity
Arnit_0200	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
Arnit_0202	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Arnit_0208	COG1879	ABC-type sugar transport system periplasmic component
Arnit_0209	COG3769	mannosylglycerate metabolic process
Arnit_0210	COG2379	hydroxypyruvate reductase
Arnit_0211	COG1215	transferase activity, transferring glycosyl groups
Arnit_0214	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
Arnit_0215	COG0363	glucosamine-6-phosphate deaminase activity
Arnit_0216	COG0129	dihydroxy-acid dehydratase activity
Arnit_0217	COG0800	Aldolase
Arnit_0219	COG0166	Belongs to the GPI family
Arnit_0222	COG2824	Alkylphosphonate utilization operon protein PhnA
Arnit_0223	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
Arnit_0224	COG2992	FlgJ-related protein
Arnit_0225	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
Arnit_0226	COG0237	dephospho-CoA kinase activity
Arnit_0227	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
Arnit_0228	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
Arnit_0231	COG1846	Transcriptional regulator
Arnit_0232	COG1741	Belongs to the pirin family
Arnit_0233	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
Arnit_0234	COG2353	YceI-like domain
Arnit_0236	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
Arnit_0237	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
Arnit_0238	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
Arnit_0240	COG0505	Belongs to the CarA family
Arnit_0243	COG4565	transcriptional regulatory protein
Arnit_0244	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
Arnit_0244	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
Arnit_0247	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
Arnit_0249	COG0489	protein tyrosine kinase activity
Arnit_0250	COG0626	cystathionine gamma-synthase activity
Arnit_0254	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
Arnit_0254	COG0140	phosphoribosyl-ATP diphosphatase activity
Arnit_0258	COG0500	methyltransferase
Arnit_0259	COG0646	methionine synthase
Arnit_0259	COG1410	methionine synthase
Arnit_0261	COG3647	Membrane
Arnit_0262	COG0174	glutamine synthetase
Arnit_0263	COG1917	Cupin 2, conserved barrel domain protein
Arnit_0263	COG2207	Transcriptional regulator
Arnit_0267	COG1854	S-ribosylhomocysteine lyase activity
Arnit_0276	COG3180	Ammonia monooxygenase
Arnit_0277	COG0288	reversible hydration of carbon dioxide
Arnit_0284	COG1013	pyruvate-flavodoxin oxidoreductase activity
Arnit_0285	COG0674	pyruvate-flavodoxin oxidoreductase activity
Arnit_0286	COG1144	Oxidoreductase
Arnit_0287	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
Arnit_0288	COG0546	phosphoglycolate phosphatase activity
Arnit_0290	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Arnit_0291	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
Arnit_0293	COG0745	RESPONSE REGULATOR receiver
Arnit_0295	COG0704	Plays a role in the regulation of phosphate uptake
Arnit_0296	COG4943	cyclic-guanylate-specific phosphodiesterase activity
Arnit_0297	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
Arnit_0298	COG0268	Binds directly to 16S ribosomal RNA
Arnit_0299	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Arnit_0300	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
Arnit_0301	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Arnit_0302	COG0746	molybdenum cofactor guanylyltransferase activity
Arnit_0303	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
Arnit_0304	COG0291	Belongs to the bacterial ribosomal protein bL35 family
Arnit_0305	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
Arnit_0308	COG0124	histidyl-tRNA synthetase
Arnit_0309	COG0575	Belongs to the CDS family
Arnit_0310	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
Arnit_0314	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
Arnit_0315	COG0023	Translation Initiation Factor
Arnit_0316	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
Arnit_0316	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
Arnit_0317	COG1324	tolerance protein
Arnit_0318	COG2022	thiamine diphosphate biosynthetic process
Arnit_0326	COG0765	amino acid transport
Arnit_0327	COG0765	amino acid transport
Arnit_0329	COG0583	DNA-binding transcription factor activity
Arnit_0335	COG4176	ABC-type proline glycine betaine transport system permease component
Arnit_0336	COG2113	Glycine betaine
Arnit_0337	COG1414	Transcriptional regulator
Arnit_0341	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
Arnit_0342	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Arnit_0343	COG1254	Belongs to the acylphosphatase family
Arnit_0344	COG1234	tRNA 3'-trailer cleavage
Arnit_0346	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
Arnit_0346	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
Arnit_0348	COG3454	Phosphonate metabolism
Arnit_0349	COG4778	phosphonate C-P lyase system protein PhnL
Arnit_0350	COG4107	phosphonate C-P lyase system protein PhnK
Arnit_0351	COG3627	carbon phosphorus lyase activity
Arnit_0355	COG3639	organic phosphonate transmembrane transporter activity
Arnit_0357	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
Arnit_0359	COG2205	protein histidine kinase activity
Arnit_0359	COG5002	protein histidine kinase activity
Arnit_0359	COG0784	Response regulator, receiver
Arnit_0362	COG0840	transmembrane signaling receptor activity
Arnit_0364	COG0166	Belongs to the GPI family
Arnit_0366	COG1858	cytochrome C peroxidase
Arnit_0373	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Arnit_0374	COG0577	efflux transmembrane transporter activity
Arnit_0374	COG1136	(ABC) transporter
Arnit_0375	COG0577	efflux transmembrane transporter activity
Arnit_0375	COG1136	(ABC) transporter
Arnit_0381	COG3279	Response regulator of the LytR AlgR family
Arnit_0382	COG0386	Belongs to the glutathione peroxidase family
Arnit_0384	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
Arnit_0385	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
Arnit_0387	COG0351	phosphomethylpyrimidine kinase
Arnit_0387	COG0352	thiamine-phosphate diphosphorylase activity
Arnit_0388	COG0840	transmembrane signaling receptor activity
Arnit_0388	COG0840	transmembrane signaling receptor activity
Arnit_0390	COG4753	response regulator
Arnit_0390	COG2207	Transcriptional regulator
Arnit_0392	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
Arnit_0394	COG0585	pseudouridine synthase activity
Arnit_0395	COG2205	protein histidine kinase activity
Arnit_0397	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Arnit_0398	COG2815	serine threonine protein kinase
Arnit_0398	COG0515	serine threonine protein kinase
Arnit_0399	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
Arnit_0402	COG0745	RESPONSE REGULATOR receiver
Arnit_0403	COG0243	molybdopterin cofactor binding
Arnit_0404	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Arnit_0404	COG1116	anion transmembrane transporter activity
Arnit_0406	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Arnit_0406	COG1116	anion transmembrane transporter activity
Arnit_0410	COG0793	Belongs to the peptidase S41A family
Arnit_0411	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
Arnit_0412	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Arnit_0413	COG0047	phosphoribosylformylglycinamidine synthase activity
Arnit_0415	COG0204	Acyl-transferase
Arnit_0416	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
Arnit_0417	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Arnit_0418	COG0018	arginyl-trna synthetase
Arnit_0421	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
Arnit_0423	COG0126	phosphoglycerate kinase activity
Arnit_0424	COG0149	triose-phosphate isomerase activity
Arnit_0425	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
Arnit_0426	COG0019	diaminopimelate decarboxylase activity
Arnit_0427	COG0647	UMP catabolic process
Arnit_0428	COG0077	Prephenate dehydratase
Arnit_0428	COG1605	Chorismate mutase
Arnit_0429	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Arnit_0430	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
Arnit_0432	COG0424	maF-like protein
Arnit_0433	COG2814	Major facilitator Superfamily
Arnit_0437	COG0791	NLP P60 protein
Arnit_0439	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Arnit_0440	COG3118	belongs to the thioredoxin family
Arnit_0441	COG0492	ferredoxin-NADP+ reductase activity
Arnit_0443	COG4191	Histidine kinase
Arnit_0444	COG0745	RESPONSE REGULATOR receiver
Arnit_0446	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
Arnit_0447	COG1053	succinate dehydrogenase
Arnit_0449	COG0492	ferredoxin-NADP+ reductase activity
Arnit_0450	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
Arnit_0451	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
Arnit_0452	COG1242	4 iron, 4 sulfur cluster binding
Arnit_0455	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
Arnit_0456	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
Arnit_0457	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
Arnit_0458	COG3278	Belongs to the heme-copper respiratory oxidase family
Arnit_0467	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
Arnit_0469	COG4773	Receptor
Arnit_0471	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
Arnit_0473	COG0157	Belongs to the NadC ModD family
Arnit_0474	COG0359	binds to the 23S rRNA
Arnit_0474	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
Arnit_0476	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
Arnit_0478	COG0083	homoserine kinase activity
Arnit_0480	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
Arnit_0481	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
Arnit_0482	COG0779	Required for maturation of 30S ribosomal subunits
Arnit_0483	COG1280	lysine exporter protein (LysE YggA)
Arnit_0484	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Arnit_0484	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Arnit_0486	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
Arnit_0487	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Arnit_0488	COG1185	polyribonucleotide nucleotidyltransferase activity
Arnit_0488	COG0539	negative regulation of cytoplasmic translation
Arnit_0489	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
Arnit_0490	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
Arnit_0491	COG0072	phenylalanine-tRNA ligase activity
Arnit_0491	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Arnit_0492	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
Arnit_0493	COG0537	adenosine 5'-monophosphoramidase activity
Arnit_0494	COG0825	malonyl-CoA metabolic process
Arnit_0495	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Arnit_0496	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Arnit_0498	COG0602	queuosine metabolic process
Arnit_0500	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
Arnit_0501	COG0303	'Molybdopterin
Arnit_0503	COG1385	rRNA (uridine-N3-)-methyltransferase activity
Arnit_0504	COG0745	RESPONSE REGULATOR receiver
Arnit_0508	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
Arnit_0509	COG0723	plastoquinol--plastocyanin reductase activity
Arnit_0510	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
Arnit_0511	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
Arnit_0514	COG0356	it plays a direct role in the translocation of protons across the membrane
Arnit_0515	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
Arnit_0516	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
Arnit_0518	COG0336	Belongs to the RNA methyltransferase TrmD family
Arnit_0519	COG0335	large ribosomal subunit rRNA binding
Arnit_0521	COG1533	DNA photolyase activity
Arnit_0523	COG1121	(ABC) transporter
Arnit_0524	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Arnit_0525	COG0586	Pfam SNARE associated Golgi protein
Arnit_0526	COG1028	Short-chain dehydrogenase reductase Sdr
Arnit_0527	COG2239	Acts as a magnesium transporter
Arnit_0529	COG2966	Psort location CytoplasmicMembrane, score
Arnit_0530	COG1609	Transcriptional regulator
Arnit_0530	COG2207	Transcriptional regulator
Arnit_0535	COG4771	TonB-dependent receptor
Arnit_0537	COG1132	(ABC) transporter
Arnit_0540	COG1971	Probably functions as a manganese efflux pump
Arnit_0544	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
Arnit_0545	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
Arnit_0548	COG0180	Tryptophanyl-tRNA synthetase
Arnit_0553	COG4774	siderophore transport
Arnit_0555	COG2207	Transcriptional regulator
Arnit_0555	COG4753	response regulator
Arnit_0556	COG4191	Histidine kinase
Arnit_0560	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
Arnit_0564	COG0848	biopolymer transport protein
Arnit_0565	COG0811	peptide transport
Arnit_0566	COG0811	peptide transport
Arnit_0570	COG4774	siderophore transport
Arnit_0571	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
Arnit_0573	COG1252	NADH dehydrogenase
Arnit_0574	COG0686	Belongs to the AlaDH PNT family
Arnit_0576	COG0840	transmembrane signaling receptor activity
Arnit_0577	COG1280	lysine exporter protein (LysE YggA)
Arnit_0578	COG1126	abc transporter atp-binding protein
Arnit_0579	COG0765	amino acid transport
Arnit_0580	COG4597	amino acid ABC transporter
Arnit_0581	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Arnit_0585	COG3043	anaerobic respiration
Arnit_0586	COG0348	domain, Protein
Arnit_0587	COG0437	4 iron, 4 sulfur cluster binding
Arnit_0588	COG0243	molybdopterin cofactor binding
Arnit_0589	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Arnit_0590	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Arnit_0590	COG1648	precorrin-2 dehydrogenase activity
Arnit_0591	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Arnit_0591	COG1648	precorrin-2 dehydrogenase activity
Arnit_0594	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Arnit_0596	COG1119	ATPase activity
Arnit_0597	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
Arnit_0599	COG2404	hydrolase activity, acting on ester bonds
Arnit_0600	COG2204	response regulator
Arnit_0601	COG0741	lytic transglycosylase activity
Arnit_0602	COG0840	transmembrane signaling receptor activity
Arnit_0603	COG0640	Transcriptional regulator
Arnit_0604	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
Arnit_0605	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Arnit_0607	COG1832	CoA-binding protein
Arnit_0608	COG0642	Histidine kinase
Arnit_0609	COG0745	RESPONSE REGULATOR receiver
Arnit_0610	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Arnit_0611	COG0191	fructose-bisphosphate aldolase activity
Arnit_0612	COG0582	viral genome integration into host DNA
Arnit_0632	COG1733	regulation of RNA biosynthetic process
Arnit_0635	COG1538	Outer membrane efflux protein
Arnit_0637	COG3287	FIST C domain
Arnit_0637	COG2199	diguanylate cyclase activity
Arnit_0637	COG2200	EAL domain
Arnit_0638	COG0848	biopolymer transport protein
Arnit_0642	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
Arnit_0643	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
Arnit_0645	COG0142	geranyltranstransferase activity
Arnit_0646	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
Arnit_0647	COG0442	prolyl-tRNA aminoacylation
Arnit_0648	COG0668	transmembrane transport
Arnit_0649	COG0617	tRNA 3'-terminal CCA addition
Arnit_0650	COG0815	Transfers the fatty acyl group on membrane lipoproteins
Arnit_0651	COG1862	Preprotein translocase
Arnit_0652	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Arnit_0653	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Arnit_0657	COG0495	leucyl-tRNA aminoacylation
Arnit_0659	COG0285	dihydrofolate synthase activity
Arnit_0660	COG0739	heme binding
Arnit_0663	COG0475	glutathione-regulated potassium exporter activity
Arnit_0663	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
Arnit_0668	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
Arnit_0669	COG0840	transmembrane signaling receptor activity
Arnit_0671	COG1271	oxidase subunit
Arnit_0677	COG0642	Histidine kinase
Arnit_0678	COG2081	HI0933 family
Arnit_0679	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Arnit_0680	COG1121	(ABC) transporter
Arnit_0683	COG1692	metallophosphoesterase
Arnit_0687	COG2226	methyltransferase
Arnit_0688	COG1570	exodeoxyribonuclease VII activity
Arnit_0690	COG4753	response regulator
Arnit_0690	COG2207	Transcriptional regulator
Arnit_0692	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Arnit_0694	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
Arnit_0695	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
Arnit_0698	COG0459	protein refolding
Arnit_0700	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
Arnit_0701	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
Arnit_0702	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
Arnit_0703	COG0352	thiamine-phosphate diphosphorylase activity
Arnit_0704	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
Arnit_0705	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
Arnit_0707	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
Arnit_0708	COG2264	protein methyltransferase activity
Arnit_0709	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Arnit_0711	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Arnit_0715	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
Arnit_0717	COG0531	amino acid
Arnit_0718	COG4302	ethanolamine ammonia-lyase activity
Arnit_0719	COG4303	Ethanolamine ammonia lyase large subunit
Arnit_0723	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
Arnit_0724	COG1090	epimerase
Arnit_0725	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
Arnit_0727	COG0840	transmembrane signaling receptor activity
Arnit_0730	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
Arnit_0731	COG0651	ATP synthesis coupled electron transport
Arnit_0732	COG0650	Formate hydrogenlyase subunit 4
Arnit_0733	COG4237	Hydrogenase 4 membrane
Arnit_0734	COG0651	ATP synthesis coupled electron transport
Arnit_0735	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
Arnit_0735	COG3261	NADH dehydrogenase
Arnit_0737	COG3260	NADH ubiquinone oxidoreductase 20
Arnit_0740	COG2116	formate transmembrane transporter activity
Arnit_0741	COG3383	formate dehydrogenase (NAD+) activity
Arnit_0744	COG0481	GTPase activity
Arnit_0746	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
Arnit_0747	COG0482	sulfurtransferase activity
Arnit_0748	COG0482	sulfurtransferase activity
Arnit_0749	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
Arnit_0750	COG0006	proline dipeptidase activity
Arnit_0751	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
Arnit_0752	COG0402	S-adenosylhomocysteine deaminase activity
Arnit_0753	COG0616	signal peptide processing
Arnit_0754	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
Arnit_0755	COG0280	phosphate acetyltransferase
Arnit_0758	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
Arnit_0761	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Arnit_0765	COG1058	Belongs to the CinA family
Arnit_0765	COG1546	Belongs to the CinA family
Arnit_0766	COG0579	oxidoreductase
Arnit_0767	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
Arnit_0771	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Arnit_0776	COG0714	Associated with various cellular activities
Arnit_0778	COG0840	transmembrane signaling receptor activity
Arnit_0779	COG0052	Belongs to the universal ribosomal protein uS2 family
Arnit_0780	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
Arnit_0781	COG1136	(ABC) transporter
Arnit_0783	COG0194	GDP metabolic process
Arnit_0784	COG2200	EAL domain
Arnit_0784	COG2199	diguanylate cyclase activity
Arnit_0784	COG3287	FIST C domain
Arnit_0785	COG2217	Heavy metal translocating P-type atpase
Arnit_0788	COG1132	(ABC) transporter
Arnit_0789	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
Arnit_0791	COG1355	regulation of microtubule-based process
Arnit_0792	COG1434	Gram-negative-bacterium-type cell wall biogenesis
Arnit_0793	COG2996	Protein conserved in bacteria
Arnit_0794	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
Arnit_0796	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
Arnit_0797	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
Arnit_0800	COG0210	DNA helicase
Arnit_0801	COG2199	diguanylate cyclase activity
Arnit_0801	COG2200	EAL domain
Arnit_0801	COG3287	FIST C domain
Arnit_0803	COG0525	valine-tRNA ligase activity
Arnit_0805	COG0446	pyridine nucleotide-disulphide oxidoreductase
Arnit_0808	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Arnit_0813	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Arnit_0814	COG1538	Outer membrane efflux protein
Arnit_0815	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
Arnit_0820	COG2814	Major facilitator Superfamily
Arnit_0821	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
Arnit_0825	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
Arnit_0827	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
Arnit_0830	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Arnit_0839	COG1704	LemA family
Arnit_0840	COG0840	transmembrane signaling receptor activity
Arnit_0842	COG1028	Short-chain dehydrogenase reductase Sdr
Arnit_0843	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Arnit_0844	COG3287	FIST C domain
Arnit_0844	COG2199	diguanylate cyclase activity
Arnit_0844	COG2200	EAL domain
Arnit_0846	COG0745	RESPONSE REGULATOR receiver
Arnit_0847	COG0840	transmembrane signaling receptor activity
Arnit_0848	COG5002	protein histidine kinase activity
Arnit_0850	COG1028	Short-chain dehydrogenase reductase Sdr
Arnit_0852	COG1917	Cupin 2, conserved barrel domain protein
Arnit_0852	COG2207	Transcriptional regulator
Arnit_0853	COG1999	signal sequence binding
Arnit_0856	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
Arnit_0859	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
Arnit_0860	COG0840	transmembrane signaling receptor activity
Arnit_0862	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
Arnit_0865	COG3706	GGDEF domain
Arnit_0869	COG2151	metal-sulfur cluster biosynthetic enzyme
Arnit_0870	COG2166	iron-sulfur cluster assembly
Arnit_0871	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Arnit_0873	COG0396	ATPase activity
Arnit_0874	COG0719	Fe-S assembly protein
Arnit_0877	COG1012	belongs to the aldehyde dehydrogenase family
Arnit_0878	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
Arnit_0881	COG0395	ABC-type sugar transport system, permease component
Arnit_0884	COG3842	ATPase activity
Arnit_0885	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
Arnit_0887	COG2188	Transcriptional regulator
Arnit_0888	COG0165	Argininosuccinate lyase
Arnit_0890	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
Arnit_0891	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Arnit_0892	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Arnit_0894	COG0556	nucleotide-excision repair
Arnit_0895	COG0681	Belongs to the peptidase S26 family
Arnit_0898	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Arnit_0907	COG0698	ribose 5-phosphate isomerase
Arnit_0908	COG0681	Belongs to the peptidase S26 family
Arnit_0909	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
Arnit_0911	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
Arnit_0912	COG0193	aminoacyl-tRNA hydrolase activity
Arnit_0915	COG0860	N-Acetylmuramoyl-L-alanine amidase
Arnit_0917	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
Arnit_0919	COG1758	RNA polymerase activity
Arnit_0920	COG0528	UMP kinase activity
Arnit_0922	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
Arnit_0923	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
Arnit_0924	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
Arnit_0926	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Arnit_0927	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
Arnit_0929	COG4191	Histidine kinase
Arnit_0930	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
Arnit_0932	COG0305	Participates in initiation and elongation during chromosome replication
Arnit_0937	COG1793	dna ligase
Arnit_0938	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Arnit_0939	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
Arnit_0939	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
Arnit_0940	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
Arnit_0941	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
Arnit_0942	COG0133	tryptophan synthase activity
Arnit_0944	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
Arnit_0947	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
Arnit_0948	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Arnit_0949	COG0251	oxidation-reduction process
Arnit_0951	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Arnit_0960	COG1104	cysteine desulfurase activity
Arnit_0962	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
Arnit_0964	COG0437	4 iron, 4 sulfur cluster binding
Arnit_0966	COG0243	molybdopterin cofactor binding
Arnit_0971	COG0437	4 iron, 4 sulfur cluster binding
Arnit_0979	COG2204	response regulator
Arnit_0982	COG1305	Transglutaminase-like
Arnit_0985	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
Arnit_0986	COG0709	Synthesizes selenophosphate from selenide and ATP
Arnit_0987	COG1921	L-seryl-tRNASec selenium transferase activity
Arnit_0993	COG0582	viral genome integration into host DNA
Arnit_1001	COG0084	hydrolase, TatD family'
Arnit_1007	COG2361	Protein of unknown function DUF86
Arnit_1011	COG2207	Transcriptional regulator
Arnit_1014	COG2759	Belongs to the formate--tetrahydrofolate ligase family
Arnit_1017	COG0581	inorganic phosphate transmembrane transporter activity
Arnit_1018	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Arnit_1021	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
Arnit_1023	COG0840	transmembrane signaling receptor activity
Arnit_1024	COG4948	Mandelate Racemase Muconate Lactonizing
Arnit_1025	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Arnit_1026	COG2084	Dehydrogenase
Arnit_1027	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Arnit_1028	COG1929	Belongs to the glycerate kinase type-1 family
Arnit_1032	COG2721	sulfolactate sulfo-lyase activity
Arnit_1034	COG1802	Transcriptional regulator
Arnit_1035	COG0469	pyruvate kinase activity
Arnit_1040	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
Arnit_1041	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Arnit_1046	COG0012	GTP binding
Arnit_1047	COG2205	protein histidine kinase activity
Arnit_1051	COG3123	guanosine phosphorylase activity
Arnit_1052	COG0745	RESPONSE REGULATOR receiver
Arnit_1053	COG3437	response regulator, receiver
Arnit_1054	COG0784	Response regulator, receiver
Arnit_1054	COG2205	protein histidine kinase activity
Arnit_1056	COG0559	Belongs to the binding-protein-dependent transport system permease family
Arnit_1060	COG0829	nickel cation binding
Arnit_1062	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Arnit_1064	COG0765	amino acid transport
Arnit_1065	COG0765	amino acid transport
Arnit_1066	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Arnit_1068	COG4266	Belongs to the allantoicase family
Arnit_1070	COG0832	Belongs to the urease beta subunit family
Arnit_1070	COG0831	urea catabolic process
Arnit_1071	COG0804	urea catabolic process
Arnit_1072	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
Arnit_1074	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
Arnit_1075	COG0848	biopolymer transport protein
Arnit_1078	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
Arnit_1079	COG0585	pseudouridine synthase activity
Arnit_1081	COG0840	transmembrane signaling receptor activity
Arnit_1082	COG0632	four-way junction helicase activity
Arnit_1083	COG1181	Belongs to the D-alanine--D-alanine ligase family
Arnit_1085	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
Arnit_1090	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Arnit_1102	COG0051	transcription antitermination factor activity, RNA binding
Arnit_1103	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
Arnit_1104	COG0088	Forms part of the polypeptide exit tunnel
Arnit_1105	COG0089	rRNA binding
Arnit_1106	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Arnit_1107	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
Arnit_1108	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
Arnit_1109	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
Arnit_1110	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
Arnit_1111	COG0255	Belongs to the universal ribosomal protein uL29 family
Arnit_1112	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
Arnit_1113	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
Arnit_1114	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
Arnit_1116	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
Arnit_1117	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
Arnit_1118	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
Arnit_1119	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
Arnit_1120	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
Arnit_1121	COG0200	Binds to the 23S rRNA
Arnit_1122	COG0201	protein transport
Arnit_1123	COG0024	Methionine aminopeptidase
Arnit_1124	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
Arnit_1125	COG3706	GGDEF domain
Arnit_1129	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
Arnit_1131	COG1032	radical SAM domain protein
Arnit_1132	COG0563	adenylate kinase activity
Arnit_1133	COG0563	adenylate kinase activity
Arnit_1136	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
Arnit_1137	COG0322	excinuclease ABC activity
Arnit_1140	COG0484	heat shock protein binding
Arnit_1141	COG2199	diguanylate cyclase activity
Arnit_1141	COG2200	EAL domain
Arnit_1141	COG3287	FIST C domain
Arnit_1142	COG0484	heat shock protein binding
Arnit_1152	COG0708	Exodeoxyribonuclease III
Arnit_1153	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Arnit_1157	COG1115	amino acid carrier protein
Arnit_1159	COG0745	RESPONSE REGULATOR receiver
Arnit_1161	COG2205	protein histidine kinase activity
Arnit_1161	COG3437	response regulator, receiver
Arnit_1161	COG3850	Histidine kinase
Arnit_1161	COG4999	Histidine kinase
Arnit_1164	COG2249	NAD(P)H dehydrogenase (quinone) activity
Arnit_1165	COG2207	Transcriptional regulator
Arnit_1167	COG1335	isochorismatase
Arnit_1170	COG2814	Major facilitator Superfamily
Arnit_1171	COG2814	Major facilitator Superfamily
Arnit_1180	COG1881	PFAM PEBP family protein
Arnit_1181	COG2226	methyltransferase
Arnit_1186	COG3706	GGDEF domain
Arnit_1190	COG1012	belongs to the aldehyde dehydrogenase family
Arnit_1191	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
Arnit_1195	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
Arnit_1196	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Arnit_1197	COG0697	spore germination
Arnit_1198	COG0583	DNA-binding transcription factor activity
Arnit_1199	COG2855	membrane
Arnit_1200	COG1027	Aspartate ammonia-lyase
Arnit_1202	COG4191	Histidine kinase
Arnit_1202	COG0784	Response regulator, receiver
Arnit_1203	COG2204	response regulator
Arnit_1210	COG0840	transmembrane signaling receptor activity
Arnit_1212	COG0579	oxidoreductase
Arnit_1214	COG1473	amidohydrolase
Arnit_1215	COG3938	Belongs to the proline racemase family
Arnit_1216	COG3321	synthase
Arnit_1216	COG0604	alcohol dehydrogenase
Arnit_1216	COG1028	Short-chain dehydrogenase reductase Sdr
Arnit_1217	COG0589	response to stress
Arnit_1218	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Arnit_1219	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
Arnit_1220	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Arnit_1221	COG0006	proline dipeptidase activity
Arnit_1222	COG1012	belongs to the aldehyde dehydrogenase family
Arnit_1223	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
Arnit_1226	COG0842	Transport permease protein
Arnit_1227	COG0842	Transport permease protein
Arnit_1228	COG1131	(ABC) transporter
Arnit_1229	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Arnit_1230	COG1528	Iron-storage protein
Arnit_1231	COG1227	inorganic diphosphatase activity
Arnit_1233	COG2207	Transcriptional regulator
Arnit_1234	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Arnit_1239	COG4335	DNA alkylation repair
Arnit_1240	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
Arnit_1246	COG2200	EAL domain
Arnit_1246	COG2199	diguanylate cyclase activity
Arnit_1246	COG3287	FIST C domain
Arnit_1247	COG0702	epimerase
Arnit_1248	COG2995	paraquat-inducible protein a
Arnit_1249	COG2995	paraquat-inducible protein a
Arnit_1250	COG3008	intermembrane lipid transfer
Arnit_1256	COG0745	RESPONSE REGULATOR receiver
Arnit_1256	COG3706	GGDEF domain
Arnit_1257	COG0326	Molecular chaperone. Has ATPase activity
Arnit_1262	COG0583	DNA-binding transcription factor activity
Arnit_1267	COG1566	PFAM secretion protein HlyD family protein
Arnit_1271	COG1846	Transcriptional regulator
Arnit_1277	COG1686	Belongs to the peptidase S11 family
Arnit_1278	COG1611	Belongs to the LOG family
Arnit_1279	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
Arnit_1282	COG0745	RESPONSE REGULATOR receiver
Arnit_1288	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Arnit_1289	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Arnit_1290	COG0473	3-isopropylmalate dehydrogenase activity
Arnit_1290	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
Arnit_1291	COG4336	lyase activity
Arnit_1293	COG0840	transmembrane signaling receptor activity
Arnit_1295	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
Arnit_1296	COG1984	allophanate hydrolase subunit 2
Arnit_1298	COG0513	Belongs to the DEAD box helicase family
Arnit_1299	COG3706	GGDEF domain
Arnit_1300	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Arnit_1302	COG1078	dGTPase activity
Arnit_1304	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
Arnit_1305	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
Arnit_1306	COG1278	Cold shock
Arnit_1309	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
Arnit_1313	COG1028	Short-chain dehydrogenase reductase Sdr
Arnit_1313	COG3347	Dehydrogenase
Arnit_1314	COG0584	glycerophosphoryl diester phosphodiesterase
Arnit_1316	COG1176	ABC-type spermidine putrescine transport system, permease component I
Arnit_1318	COG3842	ATPase activity
Arnit_1319	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
Arnit_1320	COG1070	Carbohydrate kinase
Arnit_1322	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Arnit_1326	COG2951	lytic endotransglycosylase activity
Arnit_1328	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Arnit_1329	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
Arnit_1331	COG4191	Histidine kinase
Arnit_1331	COG0745	RESPONSE REGULATOR receiver
Arnit_1331	COG2205	protein histidine kinase activity
Arnit_1332	COG1132	(ABC) transporter
Arnit_1334	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Arnit_1337	COG0739	heme binding
Arnit_1339	COG0217	transcriptional regulatory protein
Arnit_1346	COG1960	acyl-CoA dehydrogenase activity
Arnit_1347	COG1250	3-hydroxyacyl-CoA dehydrogenase
Arnit_1347	COG1024	Enoyl-CoA hydratase
Arnit_1348	COG0183	Belongs to the thiolase family
Arnit_1349	COG1022	Amp-dependent synthetase and ligase
Arnit_1350	COG1049	propionate catabolic process, 2-methylcitrate cycle
Arnit_1352	COG0395	ABC-type sugar transport system, permease component
Arnit_1354	COG1653	transport
Arnit_1355	COG3842	ATPase activity
Arnit_1356	COG1349	DNA-binding transcription factor activity
Arnit_1360	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
Arnit_1361	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
Arnit_1364	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
Arnit_1365	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
Arnit_1366	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
Arnit_1367	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
Arnit_1368	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
Arnit_1370	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
Arnit_1379	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
Arnit_1380	COG0298	carbon dioxide binding
Arnit_1381	COG0409	Hydrogenase expression formation protein
Arnit_1383	COG0309	Hydrogenase expression formation protein (HypE)
Arnit_1384	COG0375	protein maturation
Arnit_1385	COG3706	GGDEF domain
Arnit_1390	COG0410	ABC transporter
Arnit_1396	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
Arnit_1397	COG2171	N-acyltransferase activity
Arnit_1398	COG3706	GGDEF domain
Arnit_1401	COG2884	Cell division ATP-binding protein ftsE
Arnit_1402	COG0220	tRNA (guanine-N7-)-methyltransferase activity
Arnit_1404	COG0564	pseudouridine synthase activity
Arnit_1405	COG0772	Belongs to the SEDS family
Arnit_1410	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
Arnit_1411	COG3123	guanosine phosphorylase activity
Arnit_1415	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Arnit_1416	COG0066	3-isopropylmalate dehydratase activity
Arnit_1417	COG0473	3-isopropylmalate dehydrogenase activity
Arnit_1419	COG1126	abc transporter atp-binding protein
Arnit_1421	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Arnit_1422	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Arnit_1425	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Arnit_1426	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
Arnit_1427	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
Arnit_1428	COG0202	RNA polymerase activity
Arnit_1429	COG0203	ribosomal protein L17
Arnit_1430	COG0154	amidase activity
Arnit_1431	COG0516	GMP reductase activity
Arnit_1431	COG0517	IMP dehydrogenase activity
Arnit_1434	COG3655	Transcriptional regulator
Arnit_1441	COG1280	lysine exporter protein (LysE YggA)
Arnit_1444	COG2827	Endonuclease containing a URI domain
Arnit_1445	COG0716	FMN binding
Arnit_1448	COG0586	Pfam SNARE associated Golgi protein
Arnit_1452	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
Arnit_1453	COG1252	NADH dehydrogenase
Arnit_1458	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
Arnit_1459	COG2040	homocysteine
Arnit_1461	COG1280	lysine exporter protein (LysE YggA)
Arnit_1467	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
Arnit_1468	COG0488	(ABC) transporter
Arnit_1471	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Arnit_1476	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
Arnit_1480	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
Arnit_1481	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
Arnit_1506	COG2201	protein-glutamate methylesterase activity
Arnit_1516	COG0745	RESPONSE REGULATOR receiver
Arnit_1517	COG2831	hemolysin activation secretion protein
Arnit_1518	COG3210	domain, Protein
Arnit_1520	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Arnit_1522	COG1380	Effector of murein hydrolase LrgA
Arnit_1523	COG1346	cytolysis
Arnit_1525	COG0419	ATPase involved in DNA repair
Arnit_1537	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
Arnit_1540	COG1529	Aldehyde oxidase and xanthine dehydrogenase
Arnit_1540	COG2010	Cytochrome c
Arnit_1542	COG1309	transcriptional regulator
Arnit_1551	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
Arnit_1553	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Arnit_1554	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Arnit_1556	COG0521	Mo-molybdopterin cofactor biosynthetic process
Arnit_1557	COG0471	metal ion transport
Arnit_1559	COG1193	negative regulation of DNA recombination
Arnit_1560	COG0668	transmembrane transport
Arnit_1562	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Arnit_1568	COG0039	L-malate dehydrogenase activity
Arnit_1571	COG0745	RESPONSE REGULATOR receiver
Arnit_1572	COG0747	negative chemotaxis
Arnit_1573	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Arnit_1573	COG4191	Histidine kinase
Arnit_1575	COG0243	molybdopterin cofactor binding
Arnit_1577	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
Arnit_1578	COG0697	spore germination
Arnit_1579	COG1794	racemase activity, acting on amino acids and derivatives
Arnit_1580	COG2258	MOSC domain
Arnit_1583	COG1733	regulation of RNA biosynthetic process
Arnit_1585	COG2249	NAD(P)H dehydrogenase (quinone) activity
Arnit_1586	COG0778	Nitroreductase
Arnit_1593	COG1979	alcohol dehydrogenase
Arnit_1594	COG0778	Nitroreductase
Arnit_1595	COG0840	transmembrane signaling receptor activity
Arnit_1598	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Arnit_1598	COG0301	tRNA thio-modification
Arnit_1600	COG0488	(ABC) transporter
Arnit_1601	COG2203	Gaf domain
Arnit_1601	COG3706	GGDEF domain
Arnit_1601	COG4251	negative regulation of phosphorylation
Arnit_1601	COG5001	Diguanylate cyclase
Arnit_1603	COG1607	acyl-coa hydrolase
Arnit_1604	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Arnit_1608	COG0745	RESPONSE REGULATOR receiver
Arnit_1609	COG0642	Histidine kinase
Arnit_1615	COG2195	Cleaves the N-terminal amino acid of tripeptides
Arnit_1616	COG3437	response regulator, receiver
Arnit_1616	COG0784	Response regulator, receiver
Arnit_1617	COG1333	cytochrome c biogenesis protein
Arnit_1617	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Arnit_1618	COG0500	methyltransferase
Arnit_1619	COG2199	diguanylate cyclase activity
Arnit_1620	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Arnit_1621	COG2833	Protein of unknown function (DUF455)
Arnit_1623	COG2200	EAL domain
Arnit_1624	COG0259	pyridoxamine-phosphate oxidase activity
Arnit_1626	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Arnit_1630	COG2211	Major facilitator Superfamily
Arnit_1632	COG0300	oxidoreductase activity
Arnit_1633	COG0133	tryptophan synthase activity
Arnit_1635	COG0484	heat shock protein binding
Arnit_1636	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
Arnit_1640	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
Arnit_1641	COG1687	branched-chain amino acid
Arnit_1645	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
Arnit_1647	COG1555	photosystem II stabilization
Arnit_1647	COG1596	polysaccharide export
Arnit_1648	COG0189	ligase activity
Arnit_1650	COG0137	argininosuccinate synthase activity
Arnit_1652	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Arnit_1654	COG1137	ATPase activity
Arnit_1656	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
Arnit_1657	COG0784	Response regulator, receiver
Arnit_1657	COG4191	Histidine kinase
Arnit_1658	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Arnit_1658	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Arnit_1663	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
Arnit_1664	COG0247	lactate metabolic process
Arnit_1665	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Arnit_1666	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
Arnit_1670	COG0745	RESPONSE REGULATOR receiver
Arnit_1673	COG0113	porphobilinogen synthase activity
Arnit_1674	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Arnit_1675	COG0357	Ribosomal RNA small subunit methyltransferase G
Arnit_1682	COG1555	photosystem II stabilization
Arnit_1711	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
Arnit_1713	COG5016	pyruvate
Arnit_1713	COG0511	ligase activity, forming carbon-carbon bonds
Arnit_1718	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Arnit_1718	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Arnit_1720	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
Arnit_1725	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Arnit_1726	COG0612	Peptidase, M16
Arnit_1727	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
Arnit_1728	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Arnit_1729	COG0287	Prephenate dehydrogenase
Arnit_1730	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
Arnit_1733	COG0527	aspartate kinase activity
Arnit_1734	COG0494	nUDIX hydrolase
Arnit_1735	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Arnit_1736	COG2890	protein-(glutamine-N5) methyltransferase activity
Arnit_1737	COG0339	signal peptide processing
Arnit_1740	COG0582	viral genome integration into host DNA
Arnit_1755	COG0515	serine threonine protein kinase
Arnit_1755	COG2815	serine threonine protein kinase
Arnit_1757	COG3501	Rhs element vgr protein
Arnit_1760	COG3501	Rhs element vgr protein
Arnit_1767	COG2201	protein-glutamate methylesterase activity
Arnit_1768	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
Arnit_1769	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
Arnit_1771	COG0745	RESPONSE REGULATOR receiver
Arnit_1772	COG1185	polyribonucleotide nucleotidyltransferase activity
Arnit_1774	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
Arnit_1776	COG0151	Belongs to the GarS family
Arnit_1778	COG0659	secondary active sulfate transmembrane transporter activity
Arnit_1779	COG1160	GTP binding
Arnit_1781	COG1196	nuclear chromosome segregation
Arnit_1781	COG1674	ftsk spoiiie
Arnit_1782	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Arnit_1783	COG0440	acetolactate synthase activity
Arnit_1784	COG0028	Belongs to the TPP enzyme family
Arnit_1786	COG0248	Ppx GppA phosphatase
Arnit_1787	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Arnit_1788	COG3706	GGDEF domain
Arnit_1788	COG2203	Gaf domain
Arnit_1788	COG5001	Diguanylate cyclase
Arnit_1788	COG4251	negative regulation of phosphorylation
Arnit_1790	COG3118	belongs to the thioredoxin family
Arnit_1791	COG0037	tRNA processing
Arnit_1793	COG0840	transmembrane signaling receptor activity
Arnit_1795	COG1012	belongs to the aldehyde dehydrogenase family
Arnit_1796	COG0410	ABC transporter
Arnit_1805	COG3437	response regulator, receiver
Arnit_1818	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
Arnit_1823	COG1322	Protein conserved in bacteria
Arnit_1824	COG0501	Belongs to the peptidase M48B family
Arnit_1826	COG0824	Thioesterase
Arnit_1830	COG1979	alcohol dehydrogenase
Arnit_1832	COG0840	transmembrane signaling receptor activity
Arnit_1833	COG0667	Aldo Keto reductase
Arnit_1836	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
Arnit_1837	COG1492	cobalamin metabolic process
Arnit_1839	COG2095	MarC family integral membrane protein
Arnit_1840	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
Arnit_1841	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
Arnit_1842	COG0778	Nitroreductase
Arnit_1843	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Arnit_1845	COG1797	cobyrinic acid a,c-diamide synthase activity
Arnit_1846	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Arnit_1849	COG4206	TonB-dependent receptor
Arnit_1852	COG0546	phosphoglycolate phosphatase activity
Arnit_1855	COG0848	biopolymer transport protein
Arnit_1856	COG0811	peptide transport
Arnit_1858	COG0745	RESPONSE REGULATOR receiver
Arnit_1861	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
Arnit_1862	COG0788	formyltetrahydrofolate deformylase activity
Arnit_1863	COG0280	phosphate acetyltransferase
Arnit_1863	COG0281	malic enzyme
Arnit_1865	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
Arnit_1870	COG0754	glutathionylspermidine amidase activity
Arnit_1871	COG0840	transmembrane signaling receptor activity
Arnit_1873	COG1663	tetraacyldisaccharide 4'-kinase activity
Arnit_1874	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Arnit_1875	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
Arnit_1879	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
Arnit_1880	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Arnit_1881	COG0805	protein transport
Arnit_1882	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
Arnit_1884	COG4753	response regulator
Arnit_1884	COG2207	Transcriptional regulator
Arnit_1885	COG4191	Histidine kinase
Arnit_1887	COG0733	neurotransmitter:sodium symporter activity
Arnit_1892	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
Arnit_1895	COG4865	methylaspartate mutase activity
Arnit_1897	COG0318	PFAM AMP-dependent synthetase and ligase
Arnit_1898	COG2863	cytochrome
Arnit_1900	COG2199	diguanylate cyclase activity
Arnit_1900	COG2200	EAL domain
Arnit_1900	COG3287	FIST C domain
Arnit_1905	COG0275	rRNA processing
Arnit_1907	COG0776	regulation of translation
Arnit_1911	COG2205	protein histidine kinase activity
Arnit_1912	COG0745	RESPONSE REGULATOR receiver
Arnit_1917	COG0653	protein targeting
Arnit_1918	COG4591	ABC-type transport system involved in lipoprotein release permease component
Arnit_1922	COG0039	L-malate dehydrogenase activity
Arnit_1925	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
Arnit_1927	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Arnit_1927	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
Arnit_1929	COG0484	heat shock protein binding
Arnit_1930	COG0789	Transcriptional regulator
Arnit_1931	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
Arnit_1932	COG0849	cell division
Arnit_1934	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
Arnit_1936	COG1393	Belongs to the ArsC family
Arnit_1938	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Arnit_1940	COG0768	penicillin binding
Arnit_1942	COG0840	transmembrane signaling receptor activity
Arnit_1944	COG1338	Plays a role in the flagellum-specific transport system
Arnit_1945	COG0840	transmembrane signaling receptor activity
Arnit_1945	COG0840	transmembrane signaling receptor activity
Arnit_1951	COG0218	Necessary for normal cell division and for the maintenance of normal septation
Arnit_1954	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
Arnit_1955	COG0131	Imidazoleglycerol-phosphate dehydratase
Arnit_1956	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
Arnit_1957	COG0741	lytic transglycosylase activity
Arnit_1957	COG1388	LysM domain
Arnit_1958	COG0084	hydrolase, TatD family'
Arnit_1960	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
Arnit_1961	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
Arnit_1962	COG0359	binds to the 23S rRNA
Arnit_1964	COG0163	prenyltransferase activity
Arnit_1965	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
Arnit_1966	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
Arnit_1967	COG0124	histidyl-tRNA synthetase
Arnit_1968	COG1166	arginine decarboxylase activity
Arnit_1969	COG1045	serine acetyltransferase
Arnit_1971	COG0513	Belongs to the DEAD box helicase family
Arnit_1972	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
Arnit_1973	COG0668	transmembrane transport
Arnit_1974	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
Arnit_1977	COG4536	flavin adenine dinucleotide binding
Arnit_1984	COG0724	RNA recognition motif
Arnit_1987	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
Arnit_1988	COG1301	dicarboxylic acid transport
Arnit_1989	COG0697	spore germination
Arnit_1990	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Arnit_1992	COG0531	amino acid
Arnit_1995	COG2095	MarC family integral membrane protein
Arnit_2001	COG3118	belongs to the thioredoxin family
Arnit_2002	COG0450	alkyl hydroperoxide reductase
Arnit_2008	COG0745	RESPONSE REGULATOR receiver
Arnit_2009	COG1278	Cold shock
Arnit_2011	COG1028	Short-chain dehydrogenase reductase Sdr
Arnit_2017	COG0510	thiamine kinase activity
Arnit_2021	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Arnit_2024	COG1187	pseudouridine synthase activity
Arnit_2027	COG0730	response to heat
Arnit_2038	COG0745	RESPONSE REGULATOR receiver
Arnit_2039	COG5002	protein histidine kinase activity
Arnit_2040	COG0840	transmembrane signaling receptor activity
Arnit_2060	COG0518	GMP synthase (glutamine-hydrolyzing) activity
Arnit_2060	COG0519	Catalyzes the synthesis of GMP from XMP
Arnit_2062	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
Arnit_2063	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
Arnit_2067	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
Arnit_2071	COG0488	(ABC) transporter
Arnit_2072	COG1610	YqeY-like protein
Arnit_2073	COG3706	GGDEF domain
Arnit_2077	COG0529	Catalyzes the synthesis of activated sulfate
Arnit_2083	COG0745	RESPONSE REGULATOR receiver
Arnit_2085	COG0300	oxidoreductase activity
Arnit_2086	COG1757	Na H antiporter
Arnit_2087	COG1971	Probably functions as a manganese efflux pump
Arnit_2088	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Arnit_2089	COG0742	ribosomal rna small subunit methyltransferase
Arnit_2092	COG1418	mRNA catabolic process
Arnit_2094	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Arnit_2095	COG0552	protein localization to endoplasmic reticulum
Arnit_2098	COG5002	protein histidine kinase activity
Arnit_2099	COG3258	Cytochrome c
Arnit_2103	COG0328	RNA-DNA hybrid ribonuclease activity
Arnit_2112	COG1280	lysine exporter protein (LysE YggA)
Arnit_2114	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
Arnit_2116	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
Arnit_2119	COG0783	Belongs to the Dps family
Arnit_2120	COG1592	Rubrerythrin
Arnit_2122	COG0728	peptidoglycan biosynthetic process
Arnit_2123	COG1132	(ABC) transporter
Arnit_2124	COG0167	dihydroorotate dehydrogenase activity
Arnit_2127	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Arnit_2128	COG1028	Short-chain dehydrogenase reductase Sdr
Arnit_2129	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Arnit_2130	COG0750	zinc metalloprotease
Arnit_2131	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
Arnit_2135	COG0134	indole-3-glycerol-phosphate synthase activity
Arnit_2137	COG0727	PFAM Uncharacterised protein family (UPF0153)
Arnit_2138	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
Arnit_2140	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
Arnit_2140	COG0674	pyruvate-flavodoxin oxidoreductase activity
Arnit_2141	COG0028	Belongs to the TPP enzyme family
Arnit_2158	COG2176	DNA-directed DNA polymerase activity
Arnit_2159	COG0135	phosphoribosylanthranilate isomerase activity
Arnit_2160	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
Arnit_2163	COG2205	protein histidine kinase activity
Arnit_2163	COG0784	Response regulator, receiver
Arnit_2168	COG3706	GGDEF domain
Arnit_2173	COG0745	RESPONSE REGULATOR receiver
Arnit_2174	COG1666	GTP binding
Arnit_2175	COG2363	Small membrane protein
Arnit_2177	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
Arnit_2178	COG2252	PERMEase
Arnit_2181	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
Arnit_2182	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Arnit_2183	COG0243	molybdopterin cofactor binding
Arnit_2184	COG4977	sequence-specific DNA binding
Arnit_2186	COG0500	methyltransferase
Arnit_2187	COG2249	NAD(P)H dehydrogenase (quinone) activity
Arnit_2190	COG2875	Belongs to the precorrin methyltransferase family
Arnit_2192	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
Arnit_2199	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
Arnit_2200	COG3842	ATPase activity
Arnit_2204	COG1609	Transcriptional regulator
Arnit_2205	COG2203	Gaf domain
Arnit_2205	COG5001	Diguanylate cyclase
Arnit_2205	COG3706	GGDEF domain
Arnit_2205	COG4251	negative regulation of phosphorylation
Arnit_2206	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
Arnit_2206	COG2169	Transcriptional regulator
Arnit_2210	COG4221	oxidoreductase activity
Arnit_2210	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Arnit_2210	COG0300	oxidoreductase activity
Arnit_2210	COG3321	synthase
Arnit_2217	COG4771	TonB-dependent receptor
Arnit_2218	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
Arnit_2221	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Arnit_2229	COG0731	radical SAM domain protein
Arnit_2230	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
Arnit_2232	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
Arnit_2235	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
Arnit_2236	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
Arnit_2237	COG0227	Belongs to the bacterial ribosomal protein bL28 family
Arnit_2239	COG0859	PFAM glycosyl transferase family 9
Arnit_2240	COG0438	transferase activity, transferring glycosyl groups
Arnit_2245	COG0859	PFAM glycosyl transferase family 9
Arnit_2246	COG0859	PFAM glycosyl transferase family 9
Arnit_2247	COG0726	polysaccharide deacetylase
Arnit_2248	COG0438	transferase activity, transferring glycosyl groups
Arnit_2252	COG0859	PFAM glycosyl transferase family 9
Arnit_2254	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
Arnit_2255	COG0493	'glutamate synthase
Arnit_2256	COG0069	glutamate synthase activity
Arnit_2256	COG0067	glutamate synthase
Arnit_2256	COG0070	glutamate synthase
Arnit_2262	COG0745	RESPONSE REGULATOR receiver
Arnit_2265	COG0513	Belongs to the DEAD box helicase family
Arnit_2268	COG5002	protein histidine kinase activity
Arnit_2268	COG5001	Diguanylate cyclase
Arnit_2271	COG0693	protein deglycase activity
Arnit_2272	COG1414	Transcriptional regulator
Arnit_2278	COG2233	PERMEase
Arnit_2279	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
Arnit_2280	COG2354	Protein conserved in bacteria
Arnit_2281	COG2814	Major facilitator Superfamily
Arnit_2283	COG1538	Outer membrane efflux protein
Arnit_2286	COG0284	orotidine-5'-phosphate decarboxylase activity
Arnit_2287	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Arnit_2288	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
Arnit_2289	COG2877	3-deoxy-8-phosphooctulonate synthase activity
Arnit_2293	COG0697	spore germination
Arnit_2294	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Arnit_2299	COG1450	Type ii and iii secretion system protein
Arnit_2300	COG1739	Uncharacterized protein family UPF0029
Arnit_2303	COG2226	methyltransferase
Arnit_2304	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Arnit_2306	COG0277	FAD linked oxidase domain protein
Arnit_2307	COG1295	ribonuclease BN
Arnit_2317	COG1131	(ABC) transporter
Arnit_2322	COG1028	Short-chain dehydrogenase reductase Sdr
Arnit_2323	COG2986	histidine ammonia-lyase
Arnit_2327	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Arnit_2328	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Arnit_2332	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
Arnit_2333	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
Arnit_2334	COG1047	Peptidyl-prolyl cis-trans
Arnit_2337	COG0823	Involved in the tonB-independent uptake of proteins
Arnit_2339	COG0848	biopolymer transport protein
Arnit_2340	COG0811	peptide transport
Arnit_2341	COG0355	proton-transporting ATP synthase activity, rotational mechanism
Arnit_2342	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
Arnit_2343	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
Arnit_2344	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
Arnit_2345	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Arnit_2346	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
Arnit_2348	COG1475	DNA binding
Arnit_2349	COG1192	Involved in chromosome partitioning
Arnit_2352	COG3852	Histidine kinase
Arnit_2353	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
Arnit_2354	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
Arnit_2355	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Arnit_2356	COG0211	Belongs to the bacterial ribosomal protein bL27 family
Arnit_2357	COG0261	This protein binds to 23S rRNA in the presence of protein L20
Arnit_2358	COG0251	oxidation-reduction process
Arnit_2359	COG0358	DNA primase activity
Arnit_2361	COG0328	RNA-DNA hybrid ribonuclease activity
Arnit_2362	COG0571	ribonuclease III activity
Arnit_2363	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
Arnit_2364	COG1342	Belongs to the UPF0251 family
Arnit_2365	COG0501	Belongs to the peptidase M48B family
Arnit_2366	COG0588	phosphoglycerate mutase activity
Arnit_2367	COG2081	HI0933 family
Arnit_2368	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
Arnit_2370	COG0706	membrane insertase activity
Arnit_2371	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
Arnit_2373	COG0230	Belongs to the bacterial ribosomal protein bL34 family
Arnit_2374	COG0542	response to heat
Arnit_2375	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
Arnit_2379	COG3706	GGDEF domain
Arnit_2382	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Arnit_2382	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Arnit_2383	COG0179	Fumarylacetoacetate (FAA) hydrolase
Arnit_2384	COG1846	Transcriptional regulator
Arnit_2386	COG2259	Doxx family
Arnit_2391	COG0477	Major facilitator Superfamily
Arnit_2392	COG0840	transmembrane signaling receptor activity
Arnit_2395	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
Arnit_2396	COG2153	protein acetylation
Arnit_2397	COG2610	gluconate transmembrane transporter activity
Arnit_2400	COG2814	Major facilitator Superfamily
Arnit_2402	COG0138	bifunctional purine biosynthesis protein purh
Arnit_2403	COG0004	ammonium transporteR
Arnit_2404	COG1181	Belongs to the D-alanine--D-alanine ligase family
Arnit_2406	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Arnit_2408	COG0739	heme binding
Arnit_2409	COG2239	Acts as a magnesium transporter
Arnit_2412	COG1459	type II secretion system
Arnit_2416	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
Arnit_2417	COG0606	chelatase, subunit chli
Arnit_2418	COG0242	peptide deformylase activity
Arnit_2419	COG0740	serine-type endopeptidase activity
Arnit_2420	COG0544	peptidyl-prolyl cis-trans isomerase activity
Arnit_2422	COG2326	polyphosphate kinase activity
Arnit_2427	COG0625	glutathione transferase activity
Arnit_2428	COG0840	transmembrane signaling receptor activity
Arnit_2437	COG3550	peptidyl-serine autophosphorylation
Arnit_2439	COG3706	GGDEF domain
Arnit_2440	COG0513	Belongs to the DEAD box helicase family
Arnit_2442	COG2201	protein-glutamate methylesterase activity
Arnit_2443	COG0840	transmembrane signaling receptor activity
Arnit_2448	COG1918	ferrous iron import across plasma membrane
Arnit_2449	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
Arnit_2451	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
Arnit_2452	COG0159	tryptophan synthase activity
Arnit_2456	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
Arnit_2457	COG2255	four-way junction helicase activity
Arnit_2458	COG0628	permease
Arnit_2463	COG0542	response to heat
Arnit_2464	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
Arnit_2465	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
Arnit_2466	COG0527	aspartate kinase activity
Arnit_2467	COG1917	Cupin 2, conserved barrel domain protein
Arnit_2468	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
Arnit_2469	COG0456	acetyltransferase
Arnit_2474	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Arnit_2476	COG1157	protein secretion by the type III secretion system
Arnit_2478	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Arnit_2484	COG0455	bacterial-type flagellum organization
Arnit_2485	COG1419	protein localization to endoplasmic reticulum
Arnit_2488	COG3951	Flagellar rod assembly protein muramidase FlgJ
Arnit_2495	COG4786	Flagellar basal body rod
Arnit_2498	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Arnit_2500	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Arnit_2501	COG1766	The M ring may be actively involved in energy transduction
Arnit_2502	COG1815	bacterial-type flagellum-dependent cell motility
Arnit_2503	COG4786	Flagellar basal body rod
Arnit_2509	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
Arnit_2510	COG1837	Belongs to the UPF0109 family
Arnit_2511	COG0228	four-way junction DNA binding
Arnit_2512	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
Arnit_2513	COG0564	pseudouridine synthase activity
Arnit_2516	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
Arnit_2517	COG0752	glycyl-tRNA synthetase alpha subunit
Arnit_2518	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
Arnit_2519	COG0204	Acyl-transferase
Arnit_2519	COG0318	PFAM AMP-dependent synthetase and ligase
Arnit_2520	COG2962	Rard protein
Arnit_2526	COG2084	Dehydrogenase
Arnit_2527	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
Arnit_2529	COG4191	Histidine kinase
Arnit_2534	COG0745	RESPONSE REGULATOR receiver
Arnit_2539	COG1086	Polysaccharide biosynthesis protein
Arnit_2540	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Arnit_2542	COG0438	transferase activity, transferring glycosyl groups
Arnit_2543	COG0367	asparagine synthase
Arnit_2545	COG0438	transferase activity, transferring glycosyl groups
Arnit_2546	COG1132	(ABC) transporter
Arnit_2547	COG0367	asparagine synthase
Arnit_2548	COG2264	protein methyltransferase activity
Arnit_2552	COG1088	dTDP-glucose 4,6-dehydratase activity
Arnit_2561	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
Arnit_2565	COG0367	asparagine synthase
Arnit_2566	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Arnit_2567	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Arnit_2571	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
Arnit_2576	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Arnit_2577	COG0129	dihydroxy-acid dehydratase activity
Arnit_2579	COG0745	RESPONSE REGULATOR receiver
Arnit_2580	COG0642	Histidine kinase
Arnit_2582	COG0497	DNA recombination
Arnit_2583	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
Arnit_2584	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Arnit_2587	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Arnit_2588	COG0049	tRNA binding
Arnit_2589	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
Arnit_2590	COG0840	transmembrane signaling receptor activity
Arnit_2591	COG2814	Major facilitator Superfamily
Arnit_2592	COG2267	carboxylic ester hydrolase activity
Arnit_2598	COG1671	Belongs to the UPF0178 family
Arnit_2599	COG4895	conserved protein (DUF2196)
Arnit_2602	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
Arnit_2603	COG0095	Lipoate-protein ligase
Arnit_2604	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
Arnit_2605	COG0508	dehydrogenase complex catalyzes the overall conversion of
Arnit_2606	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Arnit_2612	COG0310	cobalt ion transport
Arnit_2614	COG2350	Protein conserved in bacteria
Arnit_2616	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
Arnit_2617	COG0085	RNA polymerase activity
Arnit_2618	COG0222	ribosome binding
Arnit_2619	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
Arnit_2620	COG0081	regulation of translation
Arnit_2621	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
Arnit_2622	COG0250	Participates in transcription elongation, termination and antitermination
Arnit_2624	COG0267	Belongs to the bacterial ribosomal protein bL33 family
Arnit_2625	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Arnit_2626	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
Arnit_2627	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Arnit_2628	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
Arnit_2629	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
Arnit_2630	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
Arnit_2631	COG0174	glutamine synthetase
Arnit_2632	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
Arnit_2633	COG0314	molybdopterin synthase activity
Arnit_2635	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
Arnit_2636	COG1968	undecaprenyl-diphosphatase activity
Arnit_2637	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Arnit_2638	COG0772	Belongs to the SEDS family
Arnit_2639	COG0768	penicillin binding
Arnit_2640	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Arnit_2645	COG0512	Glutamine amidotransferase of anthranilate synthase
Arnit_2646	COG1840	ABC-type Fe3 transport system, periplasmic component
Arnit_2647	COG1176	ABC-type spermidine putrescine transport system, permease component I
Arnit_2648	COG3842	ATPase activity
Arnit_2650	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
Arnit_2651	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
Arnit_2652	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Arnit_2653	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Arnit_2654	COG0649	NAD binding
Arnit_2654	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Arnit_2655	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
Arnit_2657	COG0372	Belongs to the citrate synthase family
Arnit_2659	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
Arnit_2660	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Arnit_2661	COG0839	Belongs to the complex I subunit 6 family
Arnit_2662	COG0713	ATP synthesis coupled electron transport
Arnit_2663	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
Arnit_2665	COG1007	ATP synthesis coupled electron transport
Arnit_2667	COG1053	succinate dehydrogenase
Arnit_2668	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
Arnit_2674	COG0735	belongs to the Fur family
Arnit_2684	COG0716	FMN binding
Arnit_2689	COG2183	response to ionizing radiation
Arnit_2690	COG3384	dioxygenase
Arnit_2693	COG0583	DNA-binding transcription factor activity
Arnit_2695	COG1942	4-Oxalocrotonate Tautomerase
Arnit_2697	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
Arnit_2698	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
Arnit_2700	COG2095	MarC family integral membrane protein
Arnit_2701	COG0765	amino acid transport
Arnit_2707	COG0601	transmembrane transport
Arnit_2710	COG2201	protein-glutamate methylesterase activity
Arnit_2711	COG4191	Histidine kinase
Arnit_2712	COG0514	ATP-dependent DNA helicase (RecQ)
Arnit_2714	COG3706	GGDEF domain
Arnit_2714	COG0745	RESPONSE REGULATOR receiver
Arnit_2715	COG0431	NADPH-dependent FMN reductase
Arnit_2716	COG1733	regulation of RNA biosynthetic process
Arnit_2717	COG2207	Transcriptional regulator
Arnit_2717	COG3708	Transcriptional regulator
Arnit_2720	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Arnit_2721	COG1335	isochorismatase
Arnit_2722	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Arnit_2727	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
Arnit_2729	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
Arnit_2730	COG2828	Protein conserved in bacteria
Arnit_2731	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
Arnit_2732	COG1335	isochorismatase
Arnit_2733	COG0181	hydroxymethylbilane synthase activity
Arnit_2736	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
Arnit_2737	COG2205	protein histidine kinase activity
Arnit_2738	COG1464	Belongs to the NlpA lipoprotein family
Arnit_2739	COG2011	ABC-type metal ion transport system permease component
Arnit_2740	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
Arnit_2743	COG1061	Type III restriction enzyme res subunit
Arnit_2745	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
Arnit_2746	COG0450	alkyl hydroperoxide reductase
Arnit_2748	COG0105	UTP biosynthetic process
Arnit_2750	COG0333	Belongs to the bacterial ribosomal protein bL32 family
Arnit_2751	COG0416	fatty acid biosynthetic process
Arnit_2752	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Arnit_2757	COG5002	protein histidine kinase activity
Arnit_2759	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
Arnit_2760	COG0540	Belongs to the ATCase OTCase family
Arnit_2762	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Arnit_2766	COG0469	pyruvate kinase activity
Arnit_2770	COG1053	succinate dehydrogenase
Arnit_2777	COG0784	Response regulator, receiver
Arnit_2777	COG2205	protein histidine kinase activity
Arnit_2778	COG0745	RESPONSE REGULATOR receiver
Arnit_2779	COG0439	Biotin carboxylase
Arnit_2780	COG0535	radical SAM domain protein
Arnit_2784	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
Arnit_2787	COG1131	(ABC) transporter
Arnit_2798	COG1518	maintenance of DNA repeat elements
Arnit_2801	COG1846	Transcriptional regulator
Arnit_2803	COG1116	anion transmembrane transporter activity
Arnit_2810	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
Arnit_2811	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
Arnit_2813	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Arnit_2815	COG3383	formate dehydrogenase (NAD+) activity
Arnit_2816	COG0792	nuclease activity
Arnit_2817	COG0038	chloride channel
Arnit_2819	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
Arnit_2819	COG0475	glutathione-regulated potassium exporter activity
Arnit_2820	COG0156	8-amino-7-oxononanoate synthase activity
Arnit_2821	COG0288	reversible hydration of carbon dioxide
Arnit_2823	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
Arnit_2825	COG2121	Domain of unknown function (DUF374)
Arnit_2826	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Arnit_2828	COG0195	Participates in both transcription termination and antitermination
Arnit_2829	COG0215	cysteine-tRNA ligase activity
Arnit_2831	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
Arnit_2832	COG0629	single-stranded DNA binding
Arnit_2833	COG0360	Binds together with S18 to 16S ribosomal RNA
Arnit_2835	COG0557	exoribonuclease II activity
Arnit_2836	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
Arnit_2837	COG2861	carbohydrate metabolic process
Arnit_2839	COG0840	transmembrane signaling receptor activity
Arnit_2841	COG0765	amino acid transport
Arnit_2843	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
Arnit_2846	COG0436	Aminotransferase
Arnit_2851	COG0343	queuine tRNA-ribosyltransferase activity
Arnit_2852	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Arnit_2853	COG1393	Belongs to the ArsC family
Arnit_2856	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
Arnit_2858	COG0560	Phosphoserine phosphatase
Arnit_2859	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
Arnit_2864	COG0736	holo-[acyl-carrier-protein] synthase activity
Arnit_2865	COG0601	transmembrane transport
Arnit_2866	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
Arnit_2868	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Arnit_2872	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
Arnit_2873	COG4786	Flagellar basal body rod
Arnit_2873	COG1256	bacterial-type flagellum assembly
Arnit_2873	COG4786	Flagellar basal body rod
Arnit_2873	COG1256	bacterial-type flagellum assembly
Arnit_2881	COG1706	bacterial-type flagellum-dependent cell motility
Arnit_2882	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Arnit_2883	COG0418	dihydroorotase activity
Arnit_2885	COG0004	ammonium transporteR
Arnit_2886	COG0347	Belongs to the P(II) protein family
Arnit_2887	COG0004	ammonium transporteR
Arnit_2890	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
Arnit_2891	COG4232	protein-disulfide reductase activity
Arnit_2892	COG3118	belongs to the thioredoxin family
Arnit_2895	COG0688	phosphatidylethanolamine metabolic process
Arnit_2899	COG0443	Heat shock 70 kDa protein
Arnit_2900	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Arnit_2901	COG1420	regulation of RNA biosynthetic process
Arnit_2910	COG0745	RESPONSE REGULATOR receiver
Arnit_2913	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
Arnit_2914	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
Arnit_2915	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
Arnit_2916	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Arnit_2919	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Arnit_2920	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Arnit_2921	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Arnit_2923	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
Arnit_2927	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Arnit_2928	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Arnit_2929	COG3959	Transketolase, thiamine diphosphate binding domain
Arnit_2930	COG3958	Transketolase
Arnit_2933	COG2046	Belongs to the sulfate adenylyltransferase family
Arnit_2942	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
Arnit_2942	COG0028	Belongs to the TPP enzyme family
Arnit_2946	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
Arnit_2950	COG2089	acid synthase
Arnit_2951	COG1083	cytidylyl-transferase
Arnit_2952	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Arnit_2953	COG1086	Polysaccharide biosynthesis protein
Arnit_2955	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
Arnit_2956	COG0148	phosphopyruvate hydratase activity
Arnit_2959	COG0569	domain protein
Arnit_2959	COG0475	glutathione-regulated potassium exporter activity
Arnit_2960	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
Arnit_2964	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
Arnit_2966	COG1007	ATP synthesis coupled electron transport
Arnit_2968	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
Arnit_2969	COG0713	ATP synthesis coupled electron transport
Arnit_2970	COG0839	Belongs to the complex I subunit 6 family
Arnit_2971	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Arnit_2972	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
Arnit_2976	COG0649	NAD binding
Arnit_2978	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Arnit_2979	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Arnit_2980	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Arnit_2989	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
Arnit_2990	COG1620	l-lactate permease
Arnit_2993	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Arnit_2994	COG0114	fumarate hydratase activity
Arnit_2997	COG2030	dehydratase
Arnit_3002	COG2198	Histidine kinase
Arnit_3002	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Arnit_3002	COG0784	Response regulator, receiver
Arnit_3002	COG2205	protein histidine kinase activity
Arnit_3003	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
Arnit_3005	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Arnit_3006	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Arnit_3007	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
Arnit_3010	COG2199	diguanylate cyclase activity
Arnit_3010	COG3287	FIST C domain
Arnit_3010	COG2200	EAL domain
Arnit_3011	COG5000	phosphorelay sensor kinase activity
Arnit_3012	COG0307	riboflavin synthase, alpha
Arnit_3013	COG0445	tRNA wobble uridine modification
Arnit_3028	COG0504	CTP synthase activity
Arnit_3029	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
Arnit_3037	COG1752	Esterase of the alpha-beta hydrolase superfamily
Arnit_3038	COG0587	DNA-directed DNA polymerase activity
Arnit_3039	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
Arnit_3044	COG0315	cyclic pyranopterin monophosphate synthase activity
Arnit_3045	COG0828	Belongs to the bacterial ribosomal protein bS21 family
Arnit_3046	COG3278	Belongs to the heme-copper respiratory oxidase family
Arnit_3050	COG0670	Belongs to the BI1 family
Arnit_3051	COG0352	thiamine-phosphate diphosphorylase activity
Arnit_3053	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
Arnit_3054	COG0233	cytoplasmic translational termination
Arnit_3055	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
Arnit_3057	COG2814	Major facilitator Superfamily
Arnit_3058	COG5002	protein histidine kinase activity
Arnit_3058	COG5001	Diguanylate cyclase
Arnit_3059	COG3022	response to hydroperoxide
Arnit_3064	COG1012	belongs to the aldehyde dehydrogenase family
Arnit_3066	COG0546	phosphoglycolate phosphatase activity
Arnit_3069	COG3706	GGDEF domain
Arnit_3069	COG0745	RESPONSE REGULATOR receiver
Arnit_3072	COG0204	Acyl-transferase
Arnit_3078	COG2081	HI0933 family
Arnit_3086	COG1959	2 iron, 2 sulfur cluster binding
Arnit_3087	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
Arnit_3089	COG0175	sulfate reduction
Arnit_3090	COG0175	sulfate reduction
Arnit_3091	COG2895	sulfate adenylyltransferase (ATP) activity
Arnit_3092	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Arnit_3093	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Arnit_3096	COG2010	Cytochrome c
Arnit_3097	COG1408	metallophosphoesterase
Arnit_3098	COG0840	transmembrane signaling receptor activity
Arnit_3104	COG2308	Evidence 4 Homologs of previously reported genes of
Arnit_3106	COG0071	Belongs to the small heat shock protein (HSP20) family
Arnit_3107	COG3290	protein histidine kinase activity
Arnit_3112	COG0425	Belongs to the sulfur carrier protein TusA family
Arnit_3113	COG2066	Belongs to the glutaminase family
Arnit_3118	COG2205	protein histidine kinase activity
Arnit_3119	COG4565	transcriptional regulatory protein
Arnit_3124	COG1136	(ABC) transporter
Arnit_3129	COG1408	metallophosphoesterase
Arnit_3132	COG0659	secondary active sulfate transmembrane transporter activity
Arnit_3136	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
Arnit_3142	COG0745	RESPONSE REGULATOR receiver
Arnit_3143	COG2770	Histidine kinase
Arnit_3143	COG2205	protein histidine kinase activity
Arnit_3144	COG2860	membrane
Arnit_3145	COG3706	GGDEF domain
Arnit_3147	COG2201	protein-glutamate methylesterase activity
Arnit_3148	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
Arnit_3149	COG0697	spore germination
Arnit_3150	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group