locus-tag	class	description
APORC_0001	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
APORC_0002	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
APORC_0003	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
APORC_0006	ENOG4105W39	Membrane
APORC_0008	ENOG4108BSC	Methyltransferase
APORC_0010	ENOG4105E0C	molybdate abc transporter
APORC_0012	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
APORC_0013	ENOG4105F4R	Transcriptional regulator mode
APORC_0016	ENOG4105EI2	Pseudouridine synthase
APORC_0017	ENOG4107QTF	adenylosuccinate lyase
APORC_0018	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
APORC_0019	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
APORC_0023	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
APORC_0024	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
APORC_0026	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
APORC_0027	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
APORC_0028	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
APORC_0029	ENOG4105C1J	atp-dependent rna helicase
APORC_0030	ENOG4105CJ3	phosphate transporter
APORC_0032	ENOG4105CAQ	asparagine synthetase
APORC_0034	ENOG4108IAB	Phoh family
APORC_0035	ENOG4108YXA	Membrane
APORC_0036	ENOG4105D1H	recombination factor protein RarA
APORC_0037	ENOG4105FE9	pseudouridine synthase
APORC_0038	ENOG4105C2X	Arabinose 5-phosphate isomerase
APORC_0040	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
APORC_0041	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
APORC_0044	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
APORC_0045	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
APORC_0047	ENOG4108STX	response regulator
APORC_0048	ENOG4105BZU	Histidine kinase
APORC_0052	ENOG4108YYC	ycei family
APORC_0053	ENOG4105D6E	homoserine dehydrogenase
APORC_0054	ENOG4105CHM	Aminotransferase
APORC_0056	ENOG4105C2N	RNA methyltransferase TrmH family group 3
APORC_0058	ENOG41082DI	50s ribosomal protein l31
APORC_0059	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
APORC_0061	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
APORC_0063	ENOG4105PWN	phosphate abc transporter
APORC_0064	ENOG4108M8H	domain protein
APORC_0065	ENOG4105C8U	phosphate abc transporter
APORC_0067	ENOG4105E2Z	phosphate ABC transporter (Permease
APORC_0068	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
APORC_0071	ENOG4105EFI	regulatoR
APORC_0072	ENOG4105DHQ	Histidine kinase
APORC_0075	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
APORC_0078	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
APORC_0079	ENOG4105EWK	phytoene
APORC_0080	ENOG4108HRK	Histidine kinase
APORC_0081	ENOG4105DY9	regulatoR
APORC_0087	ENOG4105QNF	Outer membrane lipoprotein
APORC_0090	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
APORC_0091	ENOG4105C0B	DNA polymerase III (alpha subunit)
APORC_0098	ENOG4108Z0Z	intracellular protease Pfpi family
APORC_0101	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
APORC_0102	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
APORC_0103	ENOG4105C58	cytochrome c oxidase accessory protein ccog
APORC_0105	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
APORC_0106	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
APORC_0107	ENOG4105BZU	Histidine kinase
APORC_0109	ENOG4107SA8	fad-dependent pyridine nucleotide-disulfide oxidoreductase
APORC_0112	ENOG4105C2I	pirin domain protein
APORC_0114	ENOG4108YYC	ycei family
APORC_0116	ENOG4107RIH	serine-glyoxylate aminotransferase
APORC_0117	ENOG4105CYE	ATP phosphoribosyltransferase regulatory subunit
APORC_0118	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
APORC_0120	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
APORC_0121	ENOG4108ZAI	phosphatidylglycerophosphatase a
APORC_0123	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
APORC_0125	ENOG4105D1F	ATP-binding protein
APORC_0127	ENOG4108Z6K	Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant (By similarity)
APORC_0128	ENOG4108JPW	Aminotransferase
APORC_0129	ENOG4108Z24	l-2,4-diaminobutyric acid acetyltransferase
APORC_0132	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
APORC_0135	ENOG4105CM2	brancheD-chain amino acid aminotransferase
APORC_0141	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
APORC_0145	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
APORC_0149	ENOG4107XGZ	Hydrolase
APORC_0152	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
APORC_0154	ENOG4105D06	uba thif-type nad fad binding protein
APORC_0156	ENOG4105D41	biosynthesis protein thiH
APORC_0157	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
APORC_0158	ENOG4105DWF	phosphomethylpyrimidine kinase
APORC_0162	ENOG410890F	Dynamin family
APORC_0170	ENOG4108UJD	30S ribosomal protein S9
APORC_0171	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
APORC_0172	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
APORC_0173	ENOG4108317	Binds directly to 16S ribosomal RNA (By similarity)
APORC_0174	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
APORC_0175	ENOG410813J	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
APORC_0176	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
APORC_0177	ENOG41080AZ	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
APORC_0181	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
APORC_0182	ENOG41084M8	50s ribosomal protein L35
APORC_0183	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
APORC_0184	ENOG4105C22	threonyL-tRNA synthetase
APORC_0191	ENOG4105KNE	Phosphatidate cytidylyltransferase
APORC_0192	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
APORC_0195	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
APORC_0208	ENOG4105C8Q	Methyl-accepting chemotaxis
APORC_0209	ENOG4105CV1	Transketolase (EC 2.2.1.1)
APORC_0213	ENOG4105CEY	Amp-dependent synthetase and ligase
APORC_0215	ENOG41085FC	arsR family transcriptional regulator
APORC_0216	ENOG4107R5R	arsenical pump membrane protein
APORC_0217	ENOG4105FGV	Chromate
APORC_0220	ENOG4108YZA	Nitrogen regulatory protein pii
APORC_0222	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
APORC_0223	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
APORC_0225	ENOG4105VS8	Flagellar biosynthetic protein fliq
APORC_0230	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
APORC_0236	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
APORC_0238	ENOG4107R03	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
APORC_0240	ENOG410829W	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
APORC_0242	ENOG4105D6U	Sodium Glutamate Symporter
APORC_0243	ENOG4105GSH	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
APORC_0245	ENOG4105EAC	phosphoserine phosphatase
APORC_0247	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
APORC_0248	ENOG4105KUZ	arsenate reductase
APORC_0249	ENOG410855J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
APORC_0250	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
APORC_0252	ENOG4105DFU	Cell wall formation (By similarity)
APORC_0253	ENOG4105DUM	transcriptional regulator, lysR family
APORC_0255	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
APORC_0256	ENOG4107Z7S	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
APORC_0257	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
APORC_0258	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
APORC_0261	ENOG4107UIK	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
APORC_0272	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
APORC_0275	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
APORC_0277	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
APORC_0280	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
APORC_0282	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
APORC_0284	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
APORC_0285	ENOG4105MGB	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
APORC_0286	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
APORC_0287	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
APORC_0291	ENOG4108JQ1	Dehydrogenase
APORC_0292	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
APORC_0293	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
APORC_0294	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
APORC_0295	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
APORC_0296	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
APORC_0300	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
APORC_0301	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
APORC_0302	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
APORC_0303	ENOG4105CHR	reductase
APORC_0306	ENOG4107XZW	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
APORC_0308	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
APORC_0309	ENOG4105DQV	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity)
APORC_0310	ENOG4107QID	Threonine synthase
APORC_0311	ENOG4105CAS	nag kinase
APORC_0312	ENOG4105C4R	Atp-dependent dna helicase
APORC_0313	ENOG4107WJT	it plays a direct role in the translocation of protons across the membrane (By similarity)
APORC_0314	ENOG4105C7B	Threonine dehydratase
APORC_0315	ENOG4107QYE	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
APORC_0317	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
APORC_0318	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
APORC_0319	ENOG4107T5V	SNARE associated Golgi
APORC_0321	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
APORC_0336	ENOG4105DDQ	anthranilate synthase
APORC_0340	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
APORC_0341	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
APORC_0342	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
APORC_0343	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
APORC_0344	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
APORC_0345	ENOG41080BE	Methyl-accepting chemotaxis sensory transducer
APORC_0345	ENOG41080BE	Methyl-accepting chemotaxis sensory transducer
APORC_0346	ENOG4105CFP	Peptidase U32
APORC_0348	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
APORC_0350	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
APORC_0351	ENOG4105EGD	dinuclear metal center protein, YbgI family
APORC_0353	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
APORC_0354	ENOG4105EI2	Pseudouridine synthase
APORC_0355	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
APORC_0356	ENOG4105K5M	30s ribosomal protein S16
APORC_0358	ENOG4105V3S	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
APORC_0361	ENOG4105CGA	flagellar basal-body rod protein FlgG
APORC_0364	ENOG4105KTQ	flagellar basal-body rod protein
APORC_0365	ENOG4105Q75	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
APORC_0366	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
APORC_0367	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
APORC_0369	ENOG4105DD5	Flagellar motor switch protein
APORC_0371	ENOG4105BZE	flagellar hook protein, FlgE
APORC_0372	ENOG4105BZE	flagellar hook protein, FlgE
APORC_0375	ENOG4105DD5	Flagellar motor switch protein
APORC_0379	ENOG4105FZW	flagellar biosynthesis regulator FlhF
APORC_0380	ENOG4107R21	site-determining protein
APORC_0382	ENOG41084DA	flagellar hook-basal body complex protein fliE
APORC_0383	ENOG4108ZC9	flagellar basal-body rod protein flgc
APORC_0386	ENOG4105D00	flagellar biosynthetic protein flhB
APORC_0388	ENOG4108JIR	Flagellum-specific ATP synthase
APORC_0390	ENOG4105D7B	Flagellar biosynthesis protein flha
APORC_0392	ENOG4107XWI	flavin reductase domain protein, FMN-binding
APORC_0393	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
APORC_0394	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
APORC_0395	ENOG4105DC7	peptidase M24
APORC_0397	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
APORC_0398	ENOG4107SYB	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
APORC_0399	ENOG4105D07	Signal peptide peptidase, SppA
APORC_0400	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
APORC_0401	ENOG4108IJ2	phosphate acetyltransferase
APORC_0402	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
APORC_0403	ENOG41083X2	DNA polymerase III, epsilon subunit
APORC_0405	ENOG4107QN1	sodium solute
APORC_0407	ENOG4107QN1	sodium solute
APORC_0409	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
APORC_0411	ENOG4107QN1	sodium solute
APORC_0413	ENOG4105US7	Histidine kinase
APORC_0422	ENOG4105CEV	competence damage-inducible protein
APORC_0423	ENOG4107RSR	Malate quinone oxidoreductase
APORC_0424	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
APORC_0428	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
APORC_0429	ENOG4105CE9	30S ribosomal protein S2
APORC_0430	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
APORC_0431	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
APORC_0433	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
APORC_0434	ENOG4105EQD	regulatoR
APORC_0435	ENOG4105C59	p-type ATPase
APORC_0438	ENOG4108JJB	ABC transporter
APORC_0439	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
APORC_0440	ENOG4105ECY	inositol monophosphatase
APORC_0441	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
APORC_0442	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
APORC_0443	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
APORC_0444	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
APORC_0445	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
APORC_0447	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
APORC_0448	ENOG4107RQ5	Methylates ribosomal protein L11 (By similarity)
APORC_0449	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
APORC_0450	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
APORC_0453	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
APORC_0454	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
APORC_0457	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
APORC_0458	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
APORC_0461	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
APORC_0462	ENOG4105ECQ	AraC Family Transcriptional Regulator
APORC_0463	ENOG4105IGJ	Zn-dependent Hydrolase of the beta-lactamase fold protein
APORC_0464	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
APORC_0466	ENOG4105C59	p-type ATPase
APORC_0467	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
APORC_0472	ENOG4105DJG	MaoC domain protein dehydratase
APORC_0475	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
APORC_0476	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
APORC_0477	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
APORC_0485	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
APORC_0486	ENOG4105CJN	penicillin-binding protein
APORC_0487	ENOG4105CNI	cell division protein FtsW
APORC_0489	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
APORC_0490	ENOG4108XUR	Pfam:DUF178
APORC_0492	ENOG4108ZEX	molybdopterin converting factor, subunit 2
APORC_0494	ENOG4105C5F	glutamine synthetase
APORC_0499	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
APORC_0500	ENOG4107RDB	Major Facilitator
APORC_0501	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
APORC_0505	ENOG4105II7	pyrroline-5-carboxylate reductase
APORC_0506	ENOG410901F	(LipO)protein
APORC_0507	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
APORC_0509	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
APORC_0510	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
APORC_0511	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
APORC_0514	ENOG4105M8K	biopolymer transport protein
APORC_0515	ENOG4105M15	transport protein ExbD
APORC_0516	ENOG4108DNJ	Pfam:TonB
APORC_0520	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
APORC_0521	ENOG4105YIC	Major outer membrane protein
APORC_0525	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
APORC_0526	ENOG4105VG0	50S ribosomal protein l34
APORC_0527	ENOG4108512	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
APORC_0528	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
APORC_0530	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
APORC_0532	ENOG4105D0M	Protease HtpX homolog
APORC_0534	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
APORC_0535	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
APORC_0536	ENOG4105CRQ	synthase (Component I)
APORC_0538	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
APORC_0539	ENOG4105CRK	lysyL-tRNA synthetase
APORC_0541	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
APORC_0542	ENOG4105CDU	Replicative dna helicase
APORC_0543	ENOG4108VAU	general secretion pathway protein G
APORC_0544	ENOG4105D05	Receptor
APORC_0548	ENOG4105D22	carbon starvation protein
APORC_0549	ENOG4105C3G	gtp-binding protein
APORC_0554	ENOG4105NBK	UPF0345 protein
APORC_0555	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
APORC_0556	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
APORC_0558	ENOG4105C8Q	Methyl-accepting chemotaxis
APORC_0559	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
APORC_0560	ENOG4105CPF	Cell wall formation (By similarity)
APORC_0562	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
APORC_0565	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
APORC_0570	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
APORC_0571	ENOG4105C2M	dna polymerase I
APORC_0577	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
APORC_0578	ENOG4105E0X	reductase
APORC_0581	ENOG4105D7W	serine acetyltransferase
APORC_0582	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
APORC_0583	ENOG4105CUT	histidyl-tRNA synthetase
APORC_0584	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
APORC_0586	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
APORC_0588	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
APORC_0589	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
APORC_0590	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
APORC_0592	ENOG4105F8V	Hydrolase, tatD family
APORC_0593	ENOG4105K6T	rare lipoprotein A
APORC_0594	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
APORC_0595	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
APORC_0598	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
APORC_0599	ENOG4105KY5	gCN5-related N-acetyltransferase
APORC_0601	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
APORC_0602	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
APORC_0603	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
APORC_0604	ENOG4105KZZ	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
APORC_0605	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
APORC_0606	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
APORC_0607	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
APORC_0608	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
APORC_0609	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
APORC_0610	ENOG41084HJ	50s ribosomal protein l29
APORC_0611	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
APORC_0612	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
APORC_0613	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
APORC_0614	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
APORC_0615	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
APORC_0616	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
APORC_0617	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
APORC_0618	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
APORC_0619	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
APORC_0620	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
APORC_0621	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
APORC_0622	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
APORC_0623	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
APORC_0626	ENOG4105C9M	aspartyl-trna synthetase
APORC_0628	ENOG4105CCT	upf0313 protein
APORC_0629	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
APORC_0630	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
APORC_0634	ENOG4105C87	Aminotransferase class I and II
APORC_0635	ENOG4105C8Q	Methyl-accepting chemotaxis
APORC_0636	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
APORC_0637	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
APORC_0638	ENOG4105C8Q	Methyl-accepting chemotaxis
APORC_0639	ENOG4105CH6	catalase
APORC_0640	ENOG4105JXB	ankyrin repeat-containing protein
APORC_0643	ENOG410624X	efflux transporter, rnd family, mfp subunit
APORC_0645	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
APORC_0646	ENOG4105CN7	Flagellar biosynthetic protein FliP
APORC_0647	ENOG4105CJN	penicillin-binding protein
APORC_0651	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
APORC_0652	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
APORC_0654	ENOG4105C34	Pseudouridine synthase
APORC_0655	ENOG4105CNI	cell division protein FtsW
APORC_0658	ENOG4108UMN	azlc family
APORC_0660	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
APORC_0661	ENOG4105NBK	UPF0345 protein
APORC_0665	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
APORC_0666	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
APORC_0667	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
APORC_0670	ENOG41067V7	50S ribosomal protein L36
APORC_0671	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
APORC_0672	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
APORC_0673	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
APORC_0674	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
APORC_0675	ENOG4108ZT0	50S ribosomal protein l17
APORC_0676	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
APORC_0677	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
APORC_0678	ENOG4105CGY	Dna recombination protein
APORC_0680	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
APORC_0681	ENOG4105EYG	tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site (By similarity)
APORC_0696	ENOG4105D17	glycoside hydrolase, family 3 domain protein
APORC_0697	ENOG4107YCR	Transcriptional regulator, ARSR family
APORC_0698	ENOG4105C59	p-type ATPase
APORC_0699	ENOG41076HS	cation diffusion facilitator family transporter
APORC_0701	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
APORC_0703	ENOG4107QN2	dihydrolipoyl dehydrogenase
APORC_0704	ENOG4107QSN	dihydrolipoamide acetyltransferase
APORC_0705	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
APORC_0706	ENOG4105DF9	Lipoate-protein, ligase
APORC_0707	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
APORC_0708	ENOG4105DDY	UPF0142 protein ycaO
APORC_0709	ENOG4108RPX	mosc domain containing protein
APORC_0710	ENOG4105C8Y	Acetylornithine aminotransferase
APORC_0711	ENOG4105DKK	Benzoate
APORC_0714	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
APORC_0715	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
APORC_0718	ENOG4108JU5	Magnesium and cobalt efflux protein
APORC_0721	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
APORC_0722	ENOG4105C9B	Cysteine desulfurase
APORC_0723	ENOG4105JRK	feS assembly protein SufD
APORC_0724	ENOG4105C3K	feS assembly ATPase SufC
APORC_0728	ENOG4106TD9	Diguanylate cyclase
APORC_0729	ENOG4105CH7	arginosuccinase
APORC_0731	ENOG4105CUZ	uba thif-type nad fad binding protein
APORC_0732	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
APORC_0734	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
APORC_0735	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
APORC_0737	ENOG4105BZU	Histidine kinase
APORC_0738	ENOG4105CSM	endonuclease III
APORC_0742	ENOG4108YZG	isomerase
APORC_0743	ENOG4105C3F	Signal peptidase i
APORC_0744	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
APORC_0745	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
APORC_0746	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
APORC_0749	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
APORC_0751	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
APORC_0752	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
APORC_0753	ENOG410692R	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
APORC_0754	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
APORC_0763	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
APORC_0766	ENOG4105D7X	high-affinity nickel-transporter
APORC_0769	ENOG4105C8Q	Methyl-accepting chemotaxis
APORC_0770	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
APORC_0772	ENOG4105C28	cystathionine
APORC_0774	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
APORC_0775	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
APORC_0777	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
APORC_0778	ENOG4105EGI	Transcriptional regulator
APORC_0792	ENOG4105C25	Primosomal protein n'
APORC_0793	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
APORC_0794	ENOG4105C5H	ABC transporter
APORC_0800	ENOG4107QHF	type ii secretion system protein e
APORC_0810	ENOG4108IUZ	ABC transporter
APORC_0812	ENOG4107QYG	anthranilate phosphoribosyltransferase
APORC_0813	ENOG410854I	s4 domain protein
APORC_0814	ENOG4105CDH	Citrulline--aspartate ligase
APORC_0815	ENOG4108Z0R	Transferase
APORC_0835	ENOG4108I5C	dEAD DEAH box helicase
APORC_0838	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
APORC_0840	ENOG4105C0D	helicase
APORC_0846	ENOG4105DFP	Integrase
APORC_0849	ENOG4105CGK	Exodeoxyribonuclease III
APORC_0854	ENOG4107QP8	phosphohexose isomerase
APORC_0855	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
APORC_0862	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
APORC_0866	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
APORC_0867	ENOG4105E9K	Isocitrate dehydrogenase
APORC_0870	ENOG4105D60	lipoprotein releasing system transmembrane protein
APORC_0871	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
APORC_0872	ENOG4105ZGC	lipoprotein carrier protein
APORC_0875	ENOG4105DQU	oxidoreductase, subunit beta
APORC_0876	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
APORC_0878	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
APORC_0879	ENOG4105QTX	Pfam:UPF0153
APORC_0881	ENOG4105DK0	Indole-3-glycerol phosphate synthase
APORC_0882	ENOG4107TS3	membrane protein, TerC
APORC_0883	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
APORC_0885	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
APORC_0886	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
APORC_0888	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
APORC_0889	ENOG4106H78	methyltransferase
APORC_0890	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
APORC_0891	ENOG4105E1F	short-chain dehydrogenase reductase
APORC_0894	ENOG4105D00	flagellar biosynthetic protein flhB
APORC_0896	ENOG4108URH	decarboxylase
APORC_0898	ENOG4105DR5	peptidase
APORC_0899	ENOG4105CDY	transcriptional regulatory protein
APORC_0900	ENOG4107QIJ	Aconitate hydratase 2
APORC_0901	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
APORC_0904	ENOG4105D52	delta-aminolevulinic acid dehydratase
APORC_0906	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
APORC_0911	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
APORC_0912	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
APORC_0914	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
APORC_0915	ENOG4105EJZ	Glucose-1-phosphate cytidylyltransferase
APORC_0916	ENOG4105FAW	cDP-glucose 4,6-dehydratase
APORC_0917	ENOG4108SMP	Nad-dependent epimerase dehydratase
APORC_0918	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
APORC_0920	ENOG4105EGZ	biosynthesis protein
APORC_0922	ENOG4105K64	Glycosyl transferase, family 2
APORC_0924	ENOG4105H63	Glycosyl transferase, family 2
APORC_0926	ENOG4108RYC	glycosyltransferase
APORC_0929	ENOG4108YZM	Toxic component of a toxin-antitoxin (TA) module (By similarity)
APORC_0930	ENOG4105CMR	udp-glucose 4-epimerase
APORC_0933	ENOG4105D4P	Coproporphyrinogen iii oxidase
APORC_0934	ENOG4105DBV	ornithine carbamoyltransferase
APORC_0935	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
APORC_0938	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
APORC_0940	ENOG4108VPT	UPF0234 protein
APORC_0941	ENOG4107VIJ	nudix hydrolase
APORC_0943	ENOG4105C8Q	Methyl-accepting chemotaxis
APORC_0946	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
APORC_0947	ENOG4105DF6	Fe-S oxidoreductase
APORC_0949	ENOG4105C94	Transporter
APORC_0950	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
APORC_0951	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
APORC_0952	ENOG4105C4K	Nad synthetase
APORC_0955	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
APORC_0957	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
APORC_0958	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
APORC_0964	ENOG4105E2X	shikimate dehydrogenase
APORC_0965	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
APORC_0966	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
APORC_0967	ENOG4105C6K	Malic enzyme
APORC_0968	ENOG4105CIY	formyltetrahydrofolate deformylase
APORC_0969	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
APORC_0974	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
APORC_0981	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
APORC_0982	ENOG4105I08	Pseudouridine synthase
APORC_0983	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
APORC_0986	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
APORC_0987	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
APORC_0988	ENOG4108JJB	ABC transporter
APORC_0991	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
APORC_0993	ENOG4105C12	Phosphoribosylglycinamide synthetase
APORC_0997	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
APORC_0998	ENOG4108VYJ	response regulator receiver protein
APORC_0999	ENOG4105CBS	Chea signal transduction histidine kinase
APORC_1000	ENOG4105BZU	Histidine kinase
APORC_1002	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
APORC_1003	ENOG4105EU0	Major facilitator Superfamily
APORC_1007	ENOG4105GVR	general secretion pathway protein D
APORC_1016	ENOG4108EU4	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
APORC_1019	ENOG4105DGW	oligopeptidase A
APORC_1020	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
APORC_1021	ENOG4105CSA	Coproporphyrinogen iii oxidase
APORC_1022	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
APORC_1023	ENOG4105CFH	Aspartokinase
APORC_1026	ENOG4105EEI	dihydropteroate synthase
APORC_1028	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
APORC_1029	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
APORC_1031	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
APORC_1036	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
APORC_1038	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
APORC_1042	ENOG4105PV1	biotin lipoyl attachment domaiN-containing protein
APORC_1043	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
APORC_1050	ENOG4105CPC	Aldo Keto reductase
APORC_1055	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
APORC_1056	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
APORC_1058	ENOG4105ED9	Protein of unknown function (DUF455)
APORC_1059	ENOG4105C5X	domain protein
APORC_1061	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
APORC_1062	ENOG4105CIN	aminoacyl-histidine dipeptidase
APORC_1063	ENOG4105CRE	cytochrome C
APORC_1065	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
APORC_1066	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
APORC_1067	ENOG4105DJV	ribulose-phosphate 3-epimerase
APORC_1068	ENOG4105HDD	phospholipase
APORC_1069	ENOG4105C37	(CBS) domain
APORC_1070	ENOG4105C98	muts2 protein
APORC_1071	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
APORC_1072	ENOG4105KVH	Transcriptional regulator
APORC_1073	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
APORC_1074	ENOG4105ECP	epimerase
APORC_1077	ENOG4105DKW	ABC transporter
APORC_1078	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
APORC_1081	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
APORC_1083	ENOG4105D49	3-dehydroquinate synthase
APORC_1095	ENOG4105CNU	cell division protein FtsK
APORC_1096	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
APORC_1097	ENOG4108ZP8	Acetolactate synthase small subunit
APORC_1098	ENOG4105C7K	acetolactate synthase
APORC_1100	ENOG4105C9X	ppx gppa phosphatase
APORC_1105	ENOG4105BZU	Histidine kinase
APORC_1106	ENOG4108J59	Extracellular solute-binding protein, family 5
APORC_1107	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
APORC_1109	ENOG4107QY8	reductase
APORC_1111	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
APORC_1113	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
APORC_1115	ENOG4105C2Y	STE24 endopeptidase EC 3.4.24.84
APORC_1117	ENOG4107YD3	Thioesterase
APORC_1120	ENOG4107S7U	Sulfide dehydrogenase
APORC_1121	ENOG410812K	response regulator receiver protein
APORC_1123	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
APORC_1124	ENOG4105XDZ	Tripartite ATP-independent periplasmic transporter
APORC_1125	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
APORC_1126	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
APORC_1128	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
APORC_1130	ENOG4105QAX	Iron-sulfur
APORC_1136	ENOG4107TUY	Histidine kinase
APORC_1137	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
APORC_1138	ENOG4105K3M	)-transporter
APORC_1141	ENOG4108KS2	transglutaminase domain protein
APORC_1142	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
APORC_1149	ENOG4105DR4	Methyltransferase
APORC_1151	ENOG4105CHM	Aminotransferase
APORC_1152	ENOG4108VKG	metal-dependent hydrolase
APORC_1155	ENOG4108IYU	L-aspartate oxidase
APORC_1156	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
APORC_1158	ENOG4106A2Z	transcriptional regulator antitoxin, MazE
APORC_1162	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
APORC_1164	ENOG4105BZ1	(ABC) transporter
APORC_1167	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
APORC_1168	ENOG4105DF3	Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds (By similarity)
APORC_1174	ENOG4105IB0	filamentous hemagglutinin family outer membrane protein
APORC_1175	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
APORC_1176	ENOG4105BZU	Histidine kinase
APORC_1179	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
APORC_1181	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
APORC_1183	ENOG410841J	DNA-binding protein Hu
APORC_1185	ENOG4105C5H	ABC transporter
APORC_1187	ENOG4105DR5	peptidase
APORC_1189	ENOG4105VSH	4-oxalocrotonate tautomerase
APORC_1198	ENOG4105VCH	membrane
APORC_1200	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
APORC_1204	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
APORC_1205	ENOG4105DX0	Hemolysin A
APORC_1206	ENOG4105DTN	riboflavin biosynthesis protein ribF
APORC_1207	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
APORC_1208	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
APORC_1210	ENOG4105CQB	FAD linked oxidase domain protein
APORC_1211	ENOG4107S2Z	UPF0761 membrane protein
APORC_1213	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
APORC_1215	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
APORC_1219	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
APORC_1220	ENOG4105M7K	Involved in the transcription termination process (By similarity)
APORC_1221	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
APORC_1225	ENOG4105DZR	Type I site-specific deoxyribonuclease
APORC_1227	ENOG4105CB5	ATP-dependent DNA helicase recG
APORC_1232	ENOG4105F5P	DNA-damage-inducible protein d
APORC_1239	ENOG410841J	DNA-binding protein Hu
APORC_1260	ENOG4108SHN	Glycosyl transferase, family 2
APORC_1266	ENOG4107S03	uridine kinase
APORC_1282	ENOG4108HE4	integrase family
APORC_1287	ENOG4105VEQ	Cold shock protein
APORC_1291	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
APORC_1303	ENOG4105MZU	cell filamentation protein
APORC_1313	ENOG4108V42	Type IV secretion system protein VirB8
APORC_1317	ENOG4108EHY	type IV secretion system
APORC_1320	ENOG4105YES	addiction module antidote protein
APORC_1323	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
APORC_1325	ENOG4105DWV	Homoserine O-trans-acetylase
APORC_1327	ENOG4105CUC	YeeE YedE family protein
APORC_1328	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
APORC_1329	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
APORC_1331	ENOG4105C7H	Helicase, RecD TraA family
APORC_1333	ENOG41090SU	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity)
APORC_1336	ENOG4106032	Glutathionylspermidine synthase
APORC_1338	ENOG4105C5H	ABC transporter
APORC_1340	ENOG4108RCM	Nitroreductase
APORC_1346	ENOG4105HMI	Membrane
APORC_1347	ENOG4105DUM	transcriptional regulator, lysR family
APORC_1349	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
APORC_1353	ENOG4108ZBE	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity)
APORC_1354	ENOG4108STX	response regulator
APORC_1356	ENOG4105NQN	cytochrome C
APORC_1358	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
APORC_1359	ENOG4105DVC	DnaJ domain protein
APORC_1360	ENOG4105KNI	merR family transcriptional Regulator
APORC_1362	ENOG41080V7	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
APORC_1365	ENOG4105CJR	Integral membrane protein (MviN
APORC_1366	ENOG4105BZ1	(ABC) transporter
APORC_1367	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
APORC_1369	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
APORC_1370	ENOG4105CAN	Short-chain dehydrogenase reductase Sdr
APORC_1371	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
APORC_1372	ENOG4105DZP	Membrane-associated zinc metalloprotease
APORC_1373	ENOG4105DFA	alanine racemase domain protein
APORC_1374	ENOG4105C8Q	Methyl-accepting chemotaxis
APORC_1375	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
APORC_1377	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
APORC_1381	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
APORC_1384	ENOG4105CE1	Ferrous iron transport protein b
APORC_1386	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
APORC_1387	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
APORC_1388	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
APORC_1389	ENOG4105F4G	Membrane
APORC_1398	ENOG4105EUJ	GTP cyclohydrolase i
APORC_1399	ENOG4105D7N	magnesium and cobalt transport protein CorA
APORC_1401	ENOG4107QHF	type ii secretion system protein e
APORC_1404	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
APORC_1405	ENOG4105C0P	Mg chelatase subunit ChlI
APORC_1407	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
APORC_1408	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
APORC_1409	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
APORC_1410	ENOG4105CSR	polyphosphate kinase 2
APORC_1411	ENOG4105CSR	polyphosphate kinase 2
APORC_1415	ENOG4105DFP	Integrase
APORC_1416	ENOG4105DZR	Type I site-specific deoxyribonuclease
APORC_1421	ENOG41082EK	Restriction modification system DNA (Specificity
APORC_1428	ENOG4108C33	Resolvase
APORC_1435	ENOG410841J	DNA-binding protein Hu
APORC_1445	ENOG4107VAM	peptidase, m28
APORC_1449	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
APORC_1492	ENOG41084IH	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
APORC_1501	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
APORC_1503	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
APORC_1506	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
APORC_1508	ENOG4105VB9	50S ribosomal protein l28
APORC_1510	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
APORC_1511	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
APORC_1512	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
APORC_1513	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
APORC_1514	ENOG4105E0M	Sulfatase
APORC_1515	ENOG4105DKP	glycosyl transferase, family 9
APORC_1517	ENOG4108I6E	Sulfatase
APORC_1518	ENOG4107R0E	Glycosyl transferase, family 2
APORC_1523	ENOG4105E68	Sulfatase
APORC_1524	ENOG41080IJ	Diacylglycerol kinase
APORC_1526	ENOG4105D16	lipopolysaccharide heptosyltransferase i
APORC_1528	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
APORC_1529	ENOG4105ECY	inositol monophosphatase
APORC_1532	ENOG4105GVR	general secretion pathway protein D
APORC_1538	ENOG4105C1Y	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis (By similarity)
APORC_1539	ENOG4105EM7	Selenocysteine-specific translation elongation factor
APORC_1548	ENOG4105BZU	Histidine kinase
APORC_1549	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
APORC_1550	ENOG4105BZU	Histidine kinase
APORC_1551	ENOG4105C1J	atp-dependent rna helicase
APORC_1553	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
APORC_1554	ENOG4105EXC	Acyl-transferase
APORC_1562	ENOG4108Z66	YbaK ebsC protein
APORC_1563	ENOG4105F1N	DNA alkylation repair
APORC_1564	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
APORC_1566	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
APORC_1568	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
APORC_1569	ENOG4105CUY	Mechanosensitive ion channel
APORC_1570	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
APORC_1571	ENOG4105K5B	UPF0225 protein
APORC_1575	ENOG4108IJ0	Aspartate ammonia-lyase
APORC_1576	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
APORC_1577	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
APORC_1578	ENOG4108YZY	peptidylprolyl cis-trans isomerase
APORC_1580	ENOG4105KCK	Peptidoglycan-associated lipoprotein
APORC_1581	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
APORC_1583	ENOG4105M8F	Biopolymer transport protein exbD tolR
APORC_1584	ENOG4105E02	MotA TolQ exbB proton channel
APORC_1585	ENOG41082MC	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
APORC_1586	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
APORC_1587	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
APORC_1588	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
APORC_1589	ENOG4105PQH	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
APORC_1590	ENOG4105YF2	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
APORC_1592	ENOG4105FA0	parb-like partition protein
APORC_1593	ENOG4107QJE	Chromosome Partitioning Protein
APORC_1594	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
APORC_1596	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
APORC_1597	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
APORC_1598	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
APORC_1599	ENOG4105K46	50S ribosomal protein l27
APORC_1600	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
APORC_1601	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
APORC_1603	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
APORC_1604	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
APORC_1606	ENOG4105CSR	polyphosphate kinase 2
APORC_1609	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
APORC_1619	ENOG4105EUU	Sel1 domain protein repeat-containing protein
APORC_1621	ENOG4105E0X	reductase
APORC_1622	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
APORC_1624	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
APORC_1625	ENOG4105BZU	Histidine kinase
APORC_1626	ENOG4105DC1	bifunctional purine biosynthesis protein purh
APORC_1627	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
APORC_1629	ENOG4105E4C	Lytic transglycosylase catalytic
APORC_1633	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
APORC_1634	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
APORC_1635	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
APORC_1636	ENOG4108VZM	50s ribosomal protein L10
APORC_1637	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
APORC_1638	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
APORC_1639	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
APORC_1642	ENOG41086AR	50S ribosomal protein L33
APORC_1643	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
APORC_1649	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
APORC_1650	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
APORC_1652	ENOG4108JQC	penicillin-binding protein 1A
APORC_1660	ENOG41088H4	Diheme cytochrome SoxA (Sulfur oxidation)
APORC_1665	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
APORC_1667	ENOG4105ENA	helicase
APORC_1669	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
APORC_1670	ENOG4105QNR	S1 RNA binding domain protein
APORC_1672	ENOG4105FDK	ABC transporter
APORC_1673	ENOG4107S90	membrAne
APORC_1674	ENOG4105C8Q	Methyl-accepting chemotaxis
APORC_1675	ENOG41074MP	UPF0103 Mediator of ErbB2-driven cell motility-containing protein
APORC_1677	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
APORC_1679	ENOG4105CVR	type I restriction-modification system
APORC_1680	ENOG4107R3N	Filamentation induced by cAMP protein fic
APORC_1682	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
APORC_1683	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
APORC_1685	ENOG41084FT	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
APORC_1686	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
APORC_1688	ENOG4108V3W	Chemotaxis protein, CheW
APORC_1689	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
APORC_1690	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
APORC_1693	ENOG4105D48	metallophosphoesterase
APORC_1694	ENOG4105GR3	Histidine kinase
APORC_1697	ENOG4105C8Q	Methyl-accepting chemotaxis
APORC_1698	ENOG4105CBX	hi0933 family
APORC_1699	ENOG4105DHQ	Histidine kinase
APORC_1700	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
APORC_1711	ENOG4107XGZ	Hydrolase
APORC_1712	ENOG4105DF3	Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds (By similarity)
APORC_1713	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
APORC_1720	ENOG4108JA2	transcriptioN-repair coupling factor
APORC_1728	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
APORC_1730	ENOG4105C8T	Leucyl-tRNA synthetase
APORC_1733	ENOG4108SEK	ompa motb domain protein
APORC_1735	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
APORC_1736	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
APORC_1737	ENOG4105VIE	preprotein translocase, subunit YajC
APORC_1738	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
APORC_1739	ENOG4105D05	Receptor
APORC_1740	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
APORC_1742	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
APORC_1743	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
APORC_1746	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
APORC_1747	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
APORC_1750	ENOG4109015	Biopolymer transport protein exbD tolR
APORC_1751	ENOG4105DSF	transport protein
APORC_1752	ENOG4105D2N	Aldolase
APORC_1753	ENOG4105EIN	peptidylprolyl cis-trans isomerase
APORC_1754	ENOG4105ETX	regulatoR
APORC_1757	ENOG4108KA0	Inherit from COG: Phosphoesterase, DHHA1
APORC_1758	ENOG41062ES	Transcriptional regulator
APORC_1759	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
APORC_1760	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
APORC_1761	ENOG4108I0Q	anthranilate phosphoribosyltransferase
APORC_1764	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
APORC_1765	ENOG4108BGM	Quinol dehydrogenase periplasmic component
APORC_1767	ENOG4108ZMS	Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity)
APORC_1771	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
APORC_1779	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
APORC_1780	ENOG4105Z6B	inner membrane protein yjfl
APORC_1781	ENOG4105C31	Tryptophanyl-tRNA synthetase
APORC_1782	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
APORC_1783	ENOG4105JJR	Histidine kinase
APORC_1784	ENOG4105C8Y	Acetylornithine aminotransferase
APORC_1786	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
APORC_1789	ENOG4105CXT	aspartate transcarbamylase
APORC_1791	ENOG4105CHJ	isochorismatase hydrolase
APORC_1792	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
APORC_1794	ENOG4107QMP	dna polymerase iii subunits gamma and tau
APORC_1795	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
APORC_1796	ENOG4105D82	Glutamate dehydrogenase
APORC_1797	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
APORC_1798	ENOG4105D3R	alkyl hydroperoxide reductase
APORC_1800	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
APORC_1802	ENOG4105YQ2	50s ribosomal protein l32
APORC_1803	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
APORC_1804	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
APORC_1808	ENOG4105E33	succinate dehydrogenase
APORC_1809	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
APORC_1810	ENOG4108S24	Fumarate reduCtase
APORC_1811	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
APORC_1812	ENOG4105C8S	subunit m
APORC_1813	ENOG4105D65	subunit l
APORC_1814	ENOG41080EA	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
APORC_1817	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
APORC_1818	ENOG4108IEH	NADH dehydrogenase subunit g
APORC_1819	ENOG4105BZN	citrate synthase
APORC_1821	ENOG4105GKE	subunit e
APORC_1822	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
APORC_1823	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
APORC_1824	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
APORC_1825	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
APORC_1826	ENOG4107XM3	UPF0442 protein
APORC_1827	ENOG4105DWK	Membrane
APORC_1829	ENOG4108VHG	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
APORC_1830	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
APORC_1832	ENOG4105C8Q	Methyl-accepting chemotaxis
APORC_1833	ENOG4105BZU	Histidine kinase
APORC_1837	ENOG4105C5I	Dehydrogenase
APORC_1839	ENOG4105CR4	methylisocitrate lyase
APORC_1840	ENOG4105BZN	citrate synthase
APORC_1841	ENOG4108I0Z	Aconitate hydratase
APORC_1842	ENOG4105C7F	AcnD-accessory protein PrpF
APORC_1843	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
APORC_1844	ENOG4105CA9	Pyruvate kinase
APORC_1846	ENOG41082UM	UPF0102 protein
APORC_1847	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
APORC_1848	ENOG4107B2H	carbonic anhydrase
APORC_1850	ENOG4105DVY	radical SAM domain protein
APORC_1852	ENOG4105KB8	(LipO)protein
APORC_1853	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
APORC_1855	ENOG4105CHV	Transcription elongation factor NusA
APORC_1856	ENOG4105C8N	cysteinyl-tRNA synthetase
APORC_1858	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
APORC_1863	ENOG4105DZR	Type I site-specific deoxyribonuclease
APORC_1870	ENOG4105CD3	dihydroorotase
APORC_1877	ENOG4108S3A	nucleotidyltransferase
APORC_1878	ENOG4105CD3	dihydroorotase
APORC_1882	ENOG4105VTR	Integrase
APORC_1883	ENOG4108UUM	single-stranded DNA-binding protein
APORC_1884	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
APORC_1886	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
APORC_1887	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
APORC_1890	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
APORC_1891	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
APORC_1892	ENOG4105C3M	thioredoxin reductase
APORC_1894	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
APORC_1897	ENOG4105BZU	Histidine kinase
APORC_1898	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
APORC_1899	ENOG4105C0H	protease
APORC_1900	ENOG4105C01	Dihydroxy-acid dehydratase
APORC_1904	ENOG4105SCY	DNAK suppressor
APORC_1905	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
APORC_1906	ENOG4108TX7	
APORC_1908	ENOG4105CN1	protease
APORC_1909	ENOG4105C8V	SAICAR synthetase
APORC_1910	ENOG4105VR9	phosphoribosylformylglycinamidine synthase
APORC_1911	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
APORC_1913	ENOG4105E9Q	Acyl-transferase
APORC_1914	ENOG4105WMR	Protein CrcB homolog
APORC_1915	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
APORC_1916	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
APORC_1917	ENOG4105C75	arginyL-tRNA synthetase
APORC_1919	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
APORC_1921	ENOG4105BZA	Phosphoglycerate kinase
APORC_1922	ENOG4105CP7	Triose-phosphate isomerase
APORC_1923	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
APORC_1924	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
APORC_1925	ENOG4105CQC	Prephenate dehydratase
APORC_1926	ENOG4105CIH	Imidazole acetol-phosphate transaminase
APORC_1927	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
APORC_1928	ENOG4105CA0	peroxidase
APORC_1929	ENOG4107YJQ	MAF-like protein
APORC_1931	ENOG41081FY	multiple antibiotic resistance (MarC)-related
APORC_1933	ENOG4107QPK	)-transporter
APORC_1935	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
APORC_1937	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
APORC_1940	ENOG4105BZU	Histidine kinase
APORC_1944	ENOG4105CA3	membrane-bound lytic murein transglycosylase
APORC_1945	ENOG4105CFG	Acts as a chaperone (By similarity)
APORC_1946	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
APORC_1947	ENOG4108122	heat-inducible transcription repressor
APORC_1951	ENOG4105G01	cobalamin (vitamin B12) biosynthesis CbiM protein
APORC_1953	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
APORC_1954	ENOG4105C45	hydrogenase expression formation protein (HypE)
APORC_1957	ENOG4105CQS	hydrogenase expression formation protein HypD
APORC_1958	ENOG4105WRB	Hydrogenase assembly chaperone hypC hupF
APORC_1959	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
APORC_1962	ENOG4108P97	
APORC_1963	ENOG4108USZ	hydrogenase
APORC_1964	ENOG4105X7T	Ni Fe-hydrogenase, b-type cytochrome subunit
APORC_1965	ENOG4105DPX	Hydrogenase, large subunit
APORC_1966	ENOG4105E3S	small subunit
APORC_1970	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
APORC_1972	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
APORC_1975	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
APORC_1976	ENOG4105I03	Flagellin
APORC_1979	ENOG4108TN2	lmbE family
APORC_1982	ENOG4105VDT	-acetyltransferase
APORC_1984	ENOG4105F0R	Cytidylyltransferase
APORC_1985	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
APORC_1986	ENOG4105C5E	polysaccharide biosynthesis protein
APORC_1988	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
APORC_1989	ENOG4105C8J	)-transporter
APORC_1990	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
APORC_1992	ENOG4105CHH	sulfate transporter
APORC_1996	ENOG4105E63	Pfam:DUF178
APORC_1997	ENOG4105D4A	Cell wall formation (By similarity)
APORC_2001	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
APORC_2002	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
APORC_2005	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
APORC_2007	ENOG4105CJW	magnesium transporter
APORC_2010	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
APORC_2011	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
APORC_2012	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
APORC_2013	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
APORC_2014	ENOG4105WPN	DNA integration recombination invertion protein
APORC_2021	ENOG4105HFZ	Membrane
APORC_2023	ENOG4105NU9	Preprotein translocase subunit SecG
APORC_2024	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
APORC_2025	ENOG4107VCP	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
APORC_2031	ENOG410802Z	Protein of unknown function (DUF328)
APORC_2032	ENOG4108JYZ	YitT family
APORC_2033	ENOG41082NP	Multiple antibiotic resistance
APORC_2037	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
APORC_2040	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
APORC_2041	ENOG4107QY8	reductase
APORC_2043	ENOG4108RMU	ferritin dps family protein
APORC_2044	ENOG4105C2C	drug resistance transporter, Bcr CflA
APORC_2046	ENOG4105BZU	Histidine kinase
APORC_2047	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
APORC_2048	ENOG4105BZS	acriflavin resistance protein
APORC_2050	ENOG4105C8Q	Methyl-accepting chemotaxis
APORC_2051	ENOG4105CBX	hi0933 family
APORC_2053	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
APORC_2057	ENOG4105C11	sulfate adenylyltransferase), subunit 2
APORC_2058	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
APORC_2060	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
APORC_2062	ENOG4105C9B	Cysteine desulfurase
APORC_2064	ENOG4107RN3	metallophosphoesterase
APORC_2068	ENOG4105BZU	Histidine kinase
APORC_2070	ENOG4105CI3	gtp-binding protein typa
APORC_2071	ENOG41066VF	YeeE YedE family protein
APORC_2072	ENOG4105KSU	Redox protein
APORC_2075	ENOG4107R2U	Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity)
APORC_2076	ENOG4107ZT3	family UPF0126
APORC_2078	ENOG4106K80	
APORC_2081	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)