locus-tag	class	description
NJU99_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NJU99_00010	COG0592	DNA-directed DNA polymerase activity
NJU99_00015	COG0187	DNA topoisomerase II activity
NJU99_00030	COG0492	ferredoxin-NADP+ reductase activity
NJU99_00045	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NJU99_00065	COG0564	pseudouridine synthase activity
NJU99_00070	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NJU99_00075	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NJU99_00080	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NJU99_00125	COG1151	hydroxylamine reductase activity
NJU99_00130	COG3852	Histidine kinase
NJU99_00145	COG2885	chlorophyll binding
NJU99_00170	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NJU99_00175	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NJU99_00180	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NJU99_00185	COG2207	Transcriptional regulator
NJU99_00185	COG4753	response regulator
NJU99_00195	COG0348	domain, Protein
NJU99_00200	COG1280	lysine exporter protein (LysE YggA)
NJU99_00220	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NJU99_00225	COG0604	alcohol dehydrogenase
NJU99_00230	COG1733	regulation of RNA biosynthetic process
NJU99_00235	COG0390	transport system, permease component
NJU99_00255	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
NJU99_00260	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NJU99_00280	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
NJU99_00285	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
NJU99_00290	COG1252	NADH dehydrogenase
NJU99_00295	COG2030	dehydratase
NJU99_00300	COG0659	secondary active sulfate transmembrane transporter activity
NJU99_00305	COG1960	acyl-CoA dehydrogenase activity
NJU99_00310	COG0247	lactate metabolic process
NJU99_00310	COG2181	nitrate reductase activity
NJU99_00315	COG2086	electron transfer activity
NJU99_00320	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
NJU99_00325	COG0500	methyltransferase
NJU99_00330	COG1250	3-hydroxyacyl-CoA dehydrogenase
NJU99_00335	COG2050	protein possibly involved in aromatic compounds catabolism
NJU99_00340	COG0824	Thioesterase
NJU99_00355	COG0183	Belongs to the thiolase family
NJU99_00360	COG5002	protein histidine kinase activity
NJU99_00375	COG0745	RESPONSE REGULATOR receiver
NJU99_00380	COG3852	Histidine kinase
NJU99_00385	COG1556	Lactate utilization protein
NJU99_00390	COG1139	Iron-sulfur cluster binding protein
NJU99_00395	COG0247	lactate metabolic process
NJU99_00410	COG0511	ligase activity, forming carbon-carbon bonds
NJU99_00415	COG0439	Biotin carboxylase
NJU99_00420	COG0513	Belongs to the DEAD box helicase family
NJU99_00430	COG0306	phosphate transporter
NJU99_00435	COG0745	RESPONSE REGULATOR receiver
NJU99_00445	COG0367	asparagine synthase
NJU99_00455	COG0778	Nitroreductase
NJU99_00460	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
NJU99_00470	COG1053	succinate dehydrogenase
NJU99_00480	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
NJU99_00485	COG1981	membrane
NJU99_00490	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
NJU99_00490	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
NJU99_00495	COG1187	pseudouridine synthase activity
NJU99_00500	COG0517	IMP dehydrogenase activity
NJU99_00500	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
NJU99_00510	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
NJU99_00515	COG0107	imidazoleglycerol-phosphate synthase activity
NJU99_00530	COG0820	rRNA (adenine-C2-)-methyltransferase activity
NJU99_00535	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NJU99_00540	COG0724	RNA recognition motif
NJU99_00550	COG0745	RESPONSE REGULATOR receiver
NJU99_00555	COG0642	Histidine kinase
NJU99_00590	COG3220	belongs to the UPF0276 family
NJU99_00605	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NJU99_00615	COG5002	protein histidine kinase activity
NJU99_00630	COG0534	Mate efflux family protein
NJU99_00635	COG0460	homoserine dehydrogenase
NJU99_00640	COG0436	Aminotransferase
NJU99_00665	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NJU99_00670	COG0254	rRNA binding
NJU99_00675	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NJU99_00695	COG0109	protoheme IX farnesyltransferase activity
NJU99_00700	COG3706	GGDEF domain
NJU99_00745	COG0784	Response regulator, receiver
NJU99_00745	COG2205	protein histidine kinase activity
NJU99_00760	COG2199	diguanylate cyclase activity
NJU99_00760	COG3287	FIST C domain
NJU99_00760	COG2200	EAL domain
NJU99_00820	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NJU99_00850	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NJU99_00860	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NJU99_00865	COG0237	dephospho-CoA kinase activity
NJU99_00870	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
NJU99_00875	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
NJU99_00880	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NJU99_00885	COG1741	Belongs to the pirin family
NJU99_00895	COG2353	YceI-like domain
NJU99_00900	COG1846	Transcriptional regulator
NJU99_00905	COG1280	lysine exporter protein (LysE YggA)
NJU99_00915	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
NJU99_00920	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
NJU99_00925	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NJU99_00935	COG0505	Belongs to the CarA family
NJU99_00950	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
NJU99_00950	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
NJU99_00960	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NJU99_00970	COG0489	protein tyrosine kinase activity
NJU99_00980	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NJU99_00980	COG0140	phosphoribosyl-ATP diphosphatase activity
NJU99_01010	COG1410	methionine synthase
NJU99_01010	COG0646	methionine synthase
NJU99_01040	COG4191	Histidine kinase
NJU99_01055	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
NJU99_01060	COG0405	Gamma-glutamyltransferase
NJU99_01075	COG1854	S-ribosylhomocysteine lyase activity
NJU99_01095	COG3180	Ammonia monooxygenase
NJU99_01105	COG0745	RESPONSE REGULATOR receiver
NJU99_01125	COG1013	pyruvate-flavodoxin oxidoreductase activity
NJU99_01140	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
NJU99_01155	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
NJU99_01160	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NJU99_01165	COG5002	protein histidine kinase activity
NJU99_01165	COG3850	Histidine kinase
NJU99_01170	COG0745	RESPONSE REGULATOR receiver
NJU99_01185	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NJU99_01190	COG0581	inorganic phosphate transmembrane transporter activity
NJU99_01195	COG0573	inorganic phosphate transmembrane transporter activity
NJU99_01200	COG4943	cyclic-guanylate-specific phosphodiesterase activity
NJU99_01215	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NJU99_01220	COG0268	Binds directly to 16S ribosomal RNA
NJU99_01225	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NJU99_01230	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NJU99_01235	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NJU99_01240	COG0746	molybdenum cofactor guanylyltransferase activity
NJU99_01245	COG0446	pyridine nucleotide-disulphide oxidoreductase
NJU99_01250	COG0446	pyridine nucleotide-disulphide oxidoreductase
NJU99_01260	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NJU99_01265	COG0291	Belongs to the bacterial ribosomal protein bL35 family
NJU99_01270	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NJU99_01275	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NJU99_01300	COG0575	Belongs to the CDS family
NJU99_01305	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
NJU99_01325	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NJU99_01335	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NJU99_01335	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
NJU99_01340	COG1324	tolerance protein
NJU99_01345	COG2022	thiamine diphosphate biosynthetic process
NJU99_01410	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
NJU99_01430	COG0585	pseudouridine synthase activity
NJU99_01445	COG0793	Belongs to the peptidase S41A family
NJU99_01450	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
NJU99_01455	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NJU99_01460	COG0047	phosphoribosylformylglycinamidine synthase activity
NJU99_01470	COG0204	Acyl-transferase
NJU99_01475	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NJU99_01480	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NJU99_01485	COG0018	arginyl-trna synthetase
NJU99_01495	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NJU99_01500	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NJU99_01505	COG0126	phosphoglycerate kinase activity
NJU99_01510	COG0149	triose-phosphate isomerase activity
NJU99_01515	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
NJU99_01520	COG0019	diaminopimelate decarboxylase activity
NJU99_01525	COG1605	Chorismate mutase
NJU99_01525	COG0077	Prephenate dehydratase
NJU99_01530	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NJU99_01535	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NJU99_01555	COG0424	maF-like protein
NJU99_01565	COG0077	Prephenate dehydratase
NJU99_01565	COG1605	Chorismate mutase
NJU99_01570	COG0473	3-isopropylmalate dehydrogenase activity
NJU99_01575	COG1028	Short-chain dehydrogenase reductase Sdr
NJU99_01580	COG0784	Response regulator, receiver
NJU99_01620	COG0633	Ferredoxin
NJU99_01620	COG0543	2 iron, 2 sulfur cluster binding
NJU99_01645	COG4569	acetaldehyde dehydrogenase (acetylating) activity
NJU99_01650	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NJU99_01665	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NJU99_01695	COG0791	NLP P60 protein
NJU99_01700	COG0791	NLP P60 protein
NJU99_01730	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NJU99_01735	COG3118	belongs to the thioredoxin family
NJU99_01740	COG3118	belongs to the thioredoxin family
NJU99_01750	COG0745	RESPONSE REGULATOR receiver
NJU99_01750	COG4191	Histidine kinase
NJU99_01750	COG2205	protein histidine kinase activity
NJU99_01755	COG0745	RESPONSE REGULATOR receiver
NJU99_01760	COG1115	amino acid carrier protein
NJU99_01765	COG0492	ferredoxin-NADP+ reductase activity
NJU99_01770	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
NJU99_01775	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NJU99_01780	COG1242	4 iron, 4 sulfur cluster binding
NJU99_01795	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NJU99_01800	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NJU99_01805	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NJU99_01810	COG3278	Belongs to the heme-copper respiratory oxidase family
NJU99_01850	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NJU99_01870	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
NJU99_01875	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NJU99_01880	COG0157	Belongs to the NadC ModD family
NJU99_01895	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
NJU99_01905	COG0083	homoserine kinase activity
NJU99_01915	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NJU99_01925	COG0779	Required for maturation of 30S ribosomal subunits
NJU99_01930	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NJU99_01930	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NJU99_01935	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NJU99_01940	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NJU99_01945	COG1185	polyribonucleotide nucleotidyltransferase activity
NJU99_01945	COG0539	negative regulation of cytoplasmic translation
NJU99_01950	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NJU99_01955	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
NJU99_01960	COG0072	phenylalanine-tRNA ligase activity
NJU99_01960	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NJU99_01965	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NJU99_01970	COG0537	adenosine 5'-monophosphoramidase activity
NJU99_01975	COG0825	malonyl-CoA metabolic process
NJU99_01980	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NJU99_01985	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NJU99_02005	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NJU99_02010	COG0303	'Molybdopterin
NJU99_02020	COG1385	rRNA (uridine-N3-)-methyltransferase activity
NJU99_02035	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
NJU99_02045	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NJU99_02050	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
NJU99_02055	COG3706	GGDEF domain
NJU99_02060	COG1074	ATP-dependent DNA helicase activity
NJU99_02070	COG0356	it plays a direct role in the translocation of protons across the membrane
NJU99_02075	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NJU99_02080	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NJU99_02090	COG0336	Belongs to the RNA methyltransferase TrmD family
NJU99_02095	COG0335	large ribosomal subunit rRNA binding
NJU99_02145	COG0410	ABC transporter
NJU99_02150	COG1012	belongs to the aldehyde dehydrogenase family
NJU99_02170	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NJU99_02175	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
NJU99_02200	COG0745	RESPONSE REGULATOR receiver
NJU99_02210	COG2274	protein secretion by the type I secretion system
NJU99_02215	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NJU99_02230	COG3706	GGDEF domain
NJU99_02260	COG0848	biopolymer transport protein
NJU99_02265	COG0811	peptide transport
NJU99_02270	COG0811	peptide transport
NJU99_02280	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NJU99_02285	COG2200	EAL domain
NJU99_02285	COG2199	diguanylate cyclase activity
NJU99_02285	COG3287	FIST C domain
NJU99_02290	COG1333	cytochrome c biogenesis protein
NJU99_02290	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NJU99_02295	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
NJU99_02300	COG3005	denitrification pathway
NJU99_02310	COG0840	transmembrane signaling receptor activity
NJU99_02330	COG3043	anaerobic respiration
NJU99_02335	COG0348	domain, Protein
NJU99_02340	COG0437	4 iron, 4 sulfur cluster binding
NJU99_02355	COG0840	transmembrane signaling receptor activity
NJU99_02360	COG1760	l-serine dehydratase
NJU99_02365	COG1126	abc transporter atp-binding protein
NJU99_02370	COG0765	amino acid transport
NJU99_02375	COG4597	amino acid ABC transporter
NJU99_02385	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NJU99_02385	COG1648	precorrin-2 dehydrogenase activity
NJU99_02405	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NJU99_02410	COG2199	diguanylate cyclase activity
NJU99_02410	COG2200	EAL domain
NJU99_02410	COG3287	FIST C domain
NJU99_02425	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NJU99_02430	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NJU99_02435	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NJU99_02445	COG2404	hydrolase activity, acting on ester bonds
NJU99_02455	COG1271	oxidase subunit
NJU99_02465	COG1832	CoA-binding protein
NJU99_02470	COG0642	Histidine kinase
NJU99_02475	COG0745	RESPONSE REGULATOR receiver
NJU99_02480	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NJU99_02485	COG0191	fructose-bisphosphate aldolase activity
NJU99_02490	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NJU99_02520	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NJU99_02525	COG1116	anion transmembrane transporter activity
NJU99_02555	COG3842	ATPase activity
NJU99_02570	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
NJU99_02585	COG0535	radical SAM domain protein
NJU99_02600	COG0745	RESPONSE REGULATOR receiver
NJU99_02605	COG2205	protein histidine kinase activity
NJU99_02625	COG0811	peptide transport
NJU99_02635	COG0840	transmembrane signaling receptor activity
NJU99_02645	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NJU99_02655	COG0142	geranyltranstransferase activity
NJU99_02660	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NJU99_02665	COG0442	prolyl-tRNA aminoacylation
NJU99_02670	COG0668	transmembrane transport
NJU99_02675	COG0617	tRNA 3'-terminal CCA addition
NJU99_02690	COG0815	Transfers the fatty acyl group on membrane lipoproteins
NJU99_02695	COG1862	Preprotein translocase
NJU99_02700	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NJU99_02705	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NJU99_02730	COG0495	leucyl-tRNA aminoacylation
NJU99_02740	COG0285	dihydrofolate synthase activity
NJU99_02770	COG2010	Cytochrome c
NJU99_02775	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
NJU99_02820	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NJU99_02835	COG2081	HI0933 family
NJU99_02840	COG2203	Gaf domain
NJU99_02840	COG4251	negative regulation of phosphorylation
NJU99_02840	COG3706	GGDEF domain
NJU99_02840	COG5001	Diguanylate cyclase
NJU99_02855	COG1999	signal sequence binding
NJU99_02865	COG0745	RESPONSE REGULATOR receiver
NJU99_02870	COG0642	Histidine kinase
NJU99_02875	COG2081	HI0933 family
NJU99_02880	COG0840	transmembrane signaling receptor activity
NJU99_02880	COG3290	protein histidine kinase activity
NJU99_02905	COG1692	metallophosphoesterase
NJU99_02930	COG1570	exodeoxyribonuclease VII activity
NJU99_02935	COG0835	chemotaxis
NJU99_02945	COG0745	RESPONSE REGULATOR receiver
NJU99_02950	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NJU99_02960	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
NJU99_02965	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NJU99_02975	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NJU99_02980	COG0459	protein refolding
NJU99_02985	COG1917	Cupin 2, conserved barrel domain protein
NJU99_02985	COG4977	sequence-specific DNA binding
NJU99_02990	COG0697	spore germination
NJU99_03015	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NJU99_03020	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NJU99_03025	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NJU99_03035	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NJU99_03040	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NJU99_03050	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NJU99_03055	COG2264	protein methyltransferase activity
NJU99_03060	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NJU99_03075	COG0784	Response regulator, receiver
NJU99_03075	COG3437	response regulator, receiver
NJU99_03080	COG2197	response regulator
NJU99_03090	COG3706	GGDEF domain
NJU99_03095	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NJU99_03115	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NJU99_03140	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
NJU99_03145	COG0732	type I restriction modification DNA specificity domain
NJU99_03165	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
NJU99_03200	COG3706	GGDEF domain
NJU99_03205	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NJU99_03210	COG1090	epimerase
NJU99_03215	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NJU99_03230	COG0481	GTPase activity
NJU99_03245	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NJU99_03250	COG0482	sulfurtransferase activity
NJU99_03255	COG0482	sulfurtransferase activity
NJU99_03260	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NJU99_03265	COG0006	proline dipeptidase activity
NJU99_03270	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
NJU99_03275	COG0402	S-adenosylhomocysteine deaminase activity
NJU99_03280	COG0616	signal peptide processing
NJU99_03290	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NJU99_03295	COG0280	phosphate acetyltransferase
NJU99_03300	COG2176	DNA-directed DNA polymerase activity
NJU99_03310	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NJU99_03320	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NJU99_03340	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NJU99_03350	COG0745	RESPONSE REGULATOR receiver
NJU99_03420	COG1546	Belongs to the CinA family
NJU99_03420	COG1058	Belongs to the CinA family
NJU99_03425	COG0579	oxidoreductase
NJU99_03430	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NJU99_03445	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NJU99_03470	COG0714	Associated with various cellular activities
NJU99_03480	COG0784	Response regulator, receiver
NJU99_03500	COG0052	Belongs to the universal ribosomal protein uS2 family
NJU99_03505	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NJU99_03510	COG1136	(ABC) transporter
NJU99_03520	COG0194	GDP metabolic process
NJU99_03525	COG3287	FIST C domain
NJU99_03525	COG2200	EAL domain
NJU99_03525	COG2199	diguanylate cyclase activity
NJU99_03530	COG2217	Heavy metal translocating P-type atpase
NJU99_03550	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
NJU99_03565	COG1355	regulation of microtubule-based process
NJU99_03570	COG1434	Gram-negative-bacterium-type cell wall biogenesis
NJU99_03575	COG1121	(ABC) transporter
NJU99_03580	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NJU99_03590	COG2996	Protein conserved in bacteria
NJU99_03595	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NJU99_03600	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NJU99_03610	COG0210	DNA helicase
NJU99_03615	COG0525	valine-tRNA ligase activity
NJU99_03630	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NJU99_03645	COG2814	Major facilitator Superfamily
NJU99_03650	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NJU99_03670	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NJU99_03675	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NJU99_03680	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NJU99_03705	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NJU99_03720	COG3287	FIST C domain
NJU99_03720	COG2200	EAL domain
NJU99_03720	COG2199	diguanylate cyclase activity
NJU99_03725	COG0840	transmembrane signaling receptor activity
NJU99_03730	COG0840	transmembrane signaling receptor activity
NJU99_03735	COG0668	transmembrane transport
NJU99_03740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NJU99_03740	COG4191	Histidine kinase
NJU99_03755	COG0840	transmembrane signaling receptor activity
NJU99_03760	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NJU99_03795	COG1858	cytochrome C peroxidase
NJU99_03805	COG1028	Short-chain dehydrogenase reductase Sdr
NJU99_03825	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NJU99_03830	COG1301	dicarboxylic acid transport
NJU99_03850	COG2207	Transcriptional regulator
NJU99_03850	COG1917	Cupin 2, conserved barrel domain protein
NJU99_03855	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NJU99_03870	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
NJU99_03885	COG1116	anion transmembrane transporter activity
NJU99_03895	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NJU99_03895	COG1116	anion transmembrane transporter activity
NJU99_03900	COG0243	molybdopterin cofactor binding
NJU99_03905	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NJU99_03915	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NJU99_03925	COG0626	cystathionine gamma-synthase activity
NJU99_03935	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
NJU99_03955	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NJU99_03960	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NJU99_04000	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NJU99_04005	COG0745	RESPONSE REGULATOR receiver
NJU99_04010	COG0642	Histidine kinase
NJU99_04025	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NJU99_04040	COG0418	dihydroorotase activity
NJU99_04050	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NJU99_04055	COG3706	GGDEF domain
NJU99_04060	COG2056	Na+-H+ antiporter family
NJU99_04065	COG5002	protein histidine kinase activity
NJU99_04065	COG5001	Diguanylate cyclase
NJU99_04075	COG2166	iron-sulfur cluster assembly
NJU99_04080	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NJU99_04085	COG0719	Fe-S assembly protein
NJU99_04090	COG0396	ATPase activity
NJU99_04095	COG0719	Fe-S assembly protein
NJU99_04100	COG0765	amino acid transport
NJU99_04105	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NJU99_04110	COG1104	cysteine desulfurase activity
NJU99_04115	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
NJU99_04115	COG2906	2 iron, 2 sulfur cluster binding
NJU99_04115	COG0822	iron-sulfur transferase activity
NJU99_04125	COG0165	Argininosuccinate lyase
NJU99_04130	COG0784	Response regulator, receiver
NJU99_04130	COG0835	chemotaxis
NJU99_04135	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
NJU99_04140	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NJU99_04145	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NJU99_04150	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NJU99_04160	COG0556	nucleotide-excision repair
NJU99_04165	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NJU99_04185	COG0698	ribose 5-phosphate isomerase
NJU99_04190	COG0681	Belongs to the peptidase S26 family
NJU99_04195	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NJU99_04200	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NJU99_04205	COG0193	aminoacyl-tRNA hydrolase activity
NJU99_04220	COG0860	N-Acetylmuramoyl-L-alanine amidase
NJU99_04230	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NJU99_04240	COG1758	RNA polymerase activity
NJU99_04245	COG0528	UMP kinase activity
NJU99_04255	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
NJU99_04260	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
NJU99_04265	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NJU99_04275	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NJU99_04280	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
NJU99_04290	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NJU99_04295	COG0305	Participates in initiation and elongation during chromosome replication
NJU99_04315	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NJU99_04345	COG0166	Belongs to the GPI family
NJU99_04355	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NJU99_04360	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
NJU99_04365	COG1086	Polysaccharide biosynthesis protein
NJU99_04370	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NJU99_04380	COG2089	acid synthase
NJU99_04385	COG2030	dehydratase
NJU99_04390	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
NJU99_04395	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NJU99_04440	COG1215	transferase activity, transferring glycosyl groups
NJU99_04445	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
NJU99_04465	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
NJU99_04465	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
NJU99_04470	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
NJU99_04475	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
NJU99_04480	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NJU99_04485	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NJU99_04490	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NJU99_04495	COG0133	tryptophan synthase activity
NJU99_04505	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NJU99_04510	COG1793	dna ligase
NJU99_04525	COG0012	GTP binding
NJU99_04550	COG3123	guanosine phosphorylase activity
NJU99_04560	COG2199	diguanylate cyclase activity
NJU99_04560	COG3287	FIST C domain
NJU99_04560	COG2200	EAL domain
NJU99_04570	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NJU99_04575	COG0585	pseudouridine synthase activity
NJU99_04585	COG0840	transmembrane signaling receptor activity
NJU99_04590	COG0632	four-way junction helicase activity
NJU99_04595	COG1181	Belongs to the D-alanine--D-alanine ligase family
NJU99_04605	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NJU99_04615	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NJU99_04640	COG1309	transcriptional regulator
NJU99_04665	COG0051	transcription antitermination factor activity, RNA binding
NJU99_04670	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NJU99_04675	COG0088	Forms part of the polypeptide exit tunnel
NJU99_04680	COG0089	rRNA binding
NJU99_04685	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NJU99_04690	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NJU99_04695	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NJU99_04700	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NJU99_04705	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NJU99_04710	COG0255	Belongs to the universal ribosomal protein uL29 family
NJU99_04715	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NJU99_04720	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NJU99_04725	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NJU99_04730	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NJU99_04735	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NJU99_04740	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NJU99_04745	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NJU99_04750	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NJU99_04755	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NJU99_04760	COG0200	Binds to the 23S rRNA
NJU99_04765	COG0201	protein transport
NJU99_04770	COG0024	Methionine aminopeptidase
NJU99_04775	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NJU99_04785	COG1573	uracil-dna glycosylase
NJU99_04795	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NJU99_04820	COG1032	radical SAM domain protein
NJU99_04825	COG0563	adenylate kinase activity
NJU99_04840	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NJU99_04845	COG0322	excinuclease ABC activity
NJU99_04875	COG0386	Belongs to the glutathione peroxidase family
NJU99_04880	COG3706	GGDEF domain
NJU99_04885	COG3706	GGDEF domain
NJU99_04895	COG2201	protein-glutamate methylesterase activity
NJU99_04915	COG0484	heat shock protein binding
NJU99_04920	COG1620	l-lactate permease
NJU99_04935	COG3852	Histidine kinase
NJU99_04960	COG0840	transmembrane signaling receptor activity
NJU99_04965	COG0745	RESPONSE REGULATOR receiver
NJU99_04975	COG0784	Response regulator, receiver
NJU99_04975	COG2205	protein histidine kinase activity
NJU99_05020	COG4266	Belongs to the allantoicase family
NJU99_05035	COG2351	hydroxyisourate hydrolase activity
NJU99_05045	COG2233	PERMEase
NJU99_05055	COG0829	nickel cation binding
NJU99_05060	COG0832	Belongs to the urease beta subunit family
NJU99_05060	COG0831	urea catabolic process
NJU99_05065	COG0804	urea catabolic process
NJU99_05070	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
NJU99_05080	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
NJU99_05145	COG0708	Exodeoxyribonuclease III
NJU99_05150	COG1017	nitric oxide dioxygenase activity
NJU99_05160	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NJU99_05190	COG0745	RESPONSE REGULATOR receiver
NJU99_05220	COG0579	oxidoreductase
NJU99_05225	COG0642	Histidine kinase
NJU99_05230	COG0745	RESPONSE REGULATOR receiver
NJU99_05275	COG1942	4-Oxalocrotonate Tautomerase
NJU99_05280	COG3264	Mechanosensitive ion channel
NJU99_05280	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
NJU99_05300	COG0189	ligase activity
NJU99_05320	COG1115	amino acid carrier protein
NJU99_05325	COG2205	protein histidine kinase activity
NJU99_05330	COG0745	RESPONSE REGULATOR receiver
NJU99_05335	COG1473	amidohydrolase
NJU99_05340	COG0006	proline dipeptidase activity
NJU99_05345	COG1012	belongs to the aldehyde dehydrogenase family
NJU99_05350	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NJU99_05360	COG1027	Aspartate ammonia-lyase
NJU99_05375	COG5002	protein histidine kinase activity
NJU99_05380	COG1227	inorganic diphosphatase activity
NJU99_05385	COG0326	Molecular chaperone. Has ATPase activity
NJU99_05395	COG0010	Belongs to the arginase family
NJU99_05400	COG4335	DNA alkylation repair
NJU99_05405	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NJU99_05410	COG2902	Dehydrogenase
NJU99_05425	COG0745	RESPONSE REGULATOR receiver
NJU99_05440	COG2995	paraquat-inducible protein a
NJU99_05445	COG3008	intermembrane lipid transfer
NJU99_05455	COG0702	epimerase
NJU99_05470	COG0326	Molecular chaperone. Has ATPase activity
NJU99_05505	COG0840	transmembrane signaling receptor activity
NJU99_05525	COG1611	Belongs to the LOG family
NJU99_05540	COG0745	RESPONSE REGULATOR receiver
NJU99_05540	COG2205	protein histidine kinase activity
NJU99_05540	COG3292	Two component regulator propeller
NJU99_05545	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
NJU99_05565	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
NJU99_05575	COG1984	allophanate hydrolase subunit 2
NJU99_05585	COG3287	FIST C domain
NJU99_05585	COG2200	EAL domain
NJU99_05585	COG2199	diguanylate cyclase activity
NJU99_05600	COG0513	Belongs to the DEAD box helicase family
NJU99_05610	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NJU99_05615	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NJU99_05620	COG5002	protein histidine kinase activity
NJU99_05635	COG0840	transmembrane signaling receptor activity
NJU99_05645	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
NJU99_05660	COG4191	Histidine kinase
NJU99_05665	COG2205	protein histidine kinase activity
NJU99_05665	COG0784	Response regulator, receiver
NJU99_05680	COG3850	Histidine kinase
NJU99_05680	COG4999	Histidine kinase
NJU99_05680	COG2205	protein histidine kinase activity
NJU99_05680	COG3437	response regulator, receiver
NJU99_05690	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NJU99_05690	COG4191	Histidine kinase
NJU99_05745	COG1921	L-seryl-tRNASec selenium transferase activity
NJU99_05790	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NJU99_05805	COG0653	protein targeting
NJU99_05810	COG2356	endonuclease I
NJU99_05830	COG4191	Histidine kinase
NJU99_05830	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NJU99_05835	COG3437	response regulator, receiver
NJU99_05835	COG0784	Response regulator, receiver
NJU99_05840	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
NJU99_05845	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
NJU99_05850	COG3639	organic phosphonate transmembrane transporter activity
NJU99_05860	COG2204	response regulator
NJU99_05865	COG4191	Histidine kinase
NJU99_05895	COG0437	4 iron, 4 sulfur cluster binding
NJU99_05905	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NJU99_05925	COG0303	'Molybdopterin
NJU99_05930	COG2998	abc-type tungstate transport system, permease component
NJU99_05935	COG4662	Binding-protein-dependent transport system inner membrane component
NJU99_05960	COG1278	Cold shock
NJU99_05965	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NJU99_05975	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NJU99_05980	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NJU99_05980	COG2169	Transcriptional regulator
NJU99_06040	COG3706	GGDEF domain
NJU99_06055	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NJU99_06075	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
NJU99_06100	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NJU99_06105	COG0436	Aminotransferase
NJU99_06115	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NJU99_06125	COG5002	protein histidine kinase activity
NJU99_06140	COG2853	Lipoprotein
NJU99_06145	COG0739	heme binding
NJU99_06150	COG1027	Aspartate ammonia-lyase
NJU99_06155	COG0217	transcriptional regulatory protein
NJU99_06185	COG1024	Enoyl-CoA hydratase
NJU99_06185	COG1250	3-hydroxyacyl-CoA dehydrogenase
NJU99_06190	COG0183	Belongs to the thiolase family
NJU99_06195	COG1022	Amp-dependent synthetase and ligase
NJU99_06205	COG0114	fumarate hydratase activity
NJU99_06215	COG1049	propionate catabolic process, 2-methylcitrate cycle
NJU99_06220	COG0564	pseudouridine synthase activity
NJU99_06235	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
NJU99_06245	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
NJU99_06250	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
NJU99_06265	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
NJU99_06285	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
NJU99_06300	COG0733	neurotransmitter:sodium symporter activity
NJU99_06310	COG2814	Major facilitator Superfamily
NJU99_06315	COG4191	Histidine kinase
NJU99_06315	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NJU99_06325	COG3706	GGDEF domain
NJU99_06345	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
NJU99_06350	COG0298	carbon dioxide binding
NJU99_06355	COG0409	Hydrogenase expression formation protein
NJU99_06360	COG0309	Hydrogenase expression formation protein (HypE)
NJU99_06395	COG0410	ABC transporter
NJU99_06415	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NJU99_06420	COG2171	N-acyltransferase activity
NJU99_06430	COG0488	(ABC) transporter
NJU99_06440	COG2199	diguanylate cyclase activity
NJU99_06440	COG2200	EAL domain
NJU99_06440	COG3287	FIST C domain
NJU99_06465	COG2884	Cell division ATP-binding protein ftsE
NJU99_06470	COG0220	tRNA (guanine-N7-)-methyltransferase activity
NJU99_06480	COG0564	pseudouridine synthase activity
NJU99_06485	COG0772	Belongs to the SEDS family
NJU99_06515	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
NJU99_06520	COG3123	guanosine phosphorylase activity
NJU99_06540	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NJU99_06545	COG0066	3-isopropylmalate dehydratase activity
NJU99_06550	COG0473	3-isopropylmalate dehydrogenase activity
NJU99_06565	COG0257	Belongs to the bacterial ribosomal protein bL36 family
NJU99_06570	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NJU99_06575	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NJU99_06580	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NJU99_06585	COG0202	RNA polymerase activity
NJU99_06590	COG0203	ribosomal protein L17
NJU99_06595	COG0154	amidase activity
NJU99_06600	COG0517	IMP dehydrogenase activity
NJU99_06600	COG0516	GMP reductase activity
NJU99_06635	COG0563	adenylate kinase activity
NJU99_06655	COG2207	Transcriptional regulator
NJU99_06655	COG1917	Cupin 2, conserved barrel domain protein
NJU99_06705	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NJU99_06715	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NJU99_06725	COG2003	Belongs to the UPF0758 family
NJU99_06760	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
NJU99_06765	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NJU99_06770	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NJU99_06795	COG2274	protein secretion by the type I secretion system
NJU99_06800	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NJU99_06845	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NJU99_06850	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NJU99_06860	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NJU99_06865	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NJU99_06875	COG0521	Mo-molybdopterin cofactor biosynthetic process
NJU99_06880	COG0471	metal ion transport
NJU99_06885	COG1193	negative regulation of DNA recombination
NJU99_06900	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NJU99_06920	COG0454	-acetyltransferase
NJU99_06930	COG1881	PFAM PEBP family protein
NJU99_06940	COG1794	racemase activity, acting on amino acids and derivatives
NJU99_06950	COG2824	Alkylphosphonate utilization operon protein PhnA
NJU99_06955	COG1119	ATPase activity
NJU99_06965	COG2207	Transcriptional regulator
NJU99_06965	COG1917	Cupin 2, conserved barrel domain protein
NJU99_06990	COG1309	transcriptional regulator
NJU99_07015	COG1733	regulation of RNA biosynthetic process
NJU99_07020	COG0778	Nitroreductase
NJU99_07040	COG1902	pentaerythritol trinitrate reductase activity
NJU99_07050	COG0778	Nitroreductase
NJU99_07085	COG2197	response regulator
NJU99_07090	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
NJU99_07120	COG0745	RESPONSE REGULATOR receiver
NJU99_07125	COG5002	protein histidine kinase activity
NJU99_07130	COG1047	Peptidyl-prolyl cis-trans
NJU99_07135	COG0301	tRNA thio-modification
NJU99_07135	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NJU99_07145	COG2199	diguanylate cyclase activity
NJU99_07145	COG2200	EAL domain
NJU99_07145	COG3287	FIST C domain
NJU99_07155	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
NJU99_07160	COG0784	Response regulator, receiver
NJU99_07160	COG5002	protein histidine kinase activity
NJU99_07160	COG2205	protein histidine kinase activity
NJU99_07165	COG0488	(ABC) transporter
NJU99_07170	COG1607	acyl-coa hydrolase
NJU99_07175	COG3850	Histidine kinase
NJU99_07175	COG4999	Histidine kinase
NJU99_07175	COG2205	protein histidine kinase activity
NJU99_07175	COG3437	response regulator, receiver
NJU99_07180	COG3437	response regulator, receiver
NJU99_07185	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NJU99_07205	COG0582	viral genome integration into host DNA
NJU99_07240	COG0745	RESPONSE REGULATOR receiver
NJU99_07270	COG2195	Cleaves the N-terminal amino acid of tripeptides
NJU99_07275	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NJU99_07275	COG1333	cytochrome c biogenesis protein
NJU99_07280	COG0500	methyltransferase
NJU99_07285	COG2199	diguanylate cyclase activity
NJU99_07285	COG2203	Gaf domain
NJU99_07290	COG4251	negative regulation of phosphorylation
NJU99_07290	COG5001	Diguanylate cyclase
NJU99_07290	COG3706	GGDEF domain
NJU99_07290	COG2203	Gaf domain
NJU99_07295	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NJU99_07310	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
NJU99_07320	COG3639	organic phosphonate transmembrane transporter activity
NJU99_07340	COG3627	carbon phosphorus lyase activity
NJU99_07345	COG4107	phosphonate C-P lyase system protein PhnK
NJU99_07350	COG4778	phosphonate C-P lyase system protein PhnL
NJU99_07355	COG3454	Phosphonate metabolism
NJU99_07365	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
NJU99_07380	COG1234	tRNA 3'-trailer cleavage
NJU99_07390	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
NJU99_07395	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
NJU99_07410	COG3040	lipid binding
NJU99_07430	COG1979	alcohol dehydrogenase
NJU99_07435	COG2207	Transcriptional regulator
NJU99_07440	COG0784	Response regulator, receiver
NJU99_07440	COG3437	response regulator, receiver
NJU99_07455	COG1408	metallophosphoesterase
NJU99_07475	COG1136	(ABC) transporter
NJU99_07485	COG3046	protein related to deoxyribodipyrimidine photolyase
NJU99_07490	COG4943	cyclic-guanylate-specific phosphodiesterase activity
NJU99_07495	COG0259	pyridoxamine-phosphate oxidase activity
NJU99_07505	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
NJU99_07525	COG2211	Major facilitator Superfamily
NJU99_07540	COG0352	thiamine-phosphate diphosphorylase activity
NJU99_07545	COG0351	phosphomethylpyrimidine kinase
NJU99_07565	COG0133	tryptophan synthase activity
NJU99_07575	COG0484	heat shock protein binding
NJU99_07585	COG0840	transmembrane signaling receptor activity
NJU99_07600	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NJU99_07610	COG1596	polysaccharide export
NJU99_07610	COG1555	photosystem II stabilization
NJU99_07615	COG0189	ligase activity
NJU99_07625	COG0137	argininosuccinate synthase activity
NJU99_07635	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NJU99_07640	COG0802	atpase or kinase
NJU99_07645	COG1137	ATPase activity
NJU99_07650	COG3706	GGDEF domain
NJU99_07655	COG3287	FIST C domain
NJU99_07655	COG2199	diguanylate cyclase activity
NJU99_07655	COG2200	EAL domain
NJU99_07660	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
NJU99_07665	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NJU99_07665	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NJU99_07685	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NJU99_07690	COG0247	lactate metabolic process
NJU99_07690	COG2181	nitrate reductase activity
NJU99_07695	COG0584	glycerophosphoryl diester phosphodiesterase
NJU99_07700	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NJU99_07705	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NJU99_07710	COG0113	porphobilinogen synthase activity
NJU99_07715	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NJU99_07720	COG0357	Ribosomal RNA small subunit methyltransferase G
NJU99_07785	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
NJU99_07795	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NJU99_07800	COG3630	sodium ion export across plasma membrane
NJU99_07815	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NJU99_07815	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NJU99_07825	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
NJU99_07855	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NJU99_07860	COG0612	Peptidase, M16
NJU99_07865	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
NJU99_07870	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NJU99_07875	COG0287	Prephenate dehydrogenase
NJU99_07880	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NJU99_07895	COG0527	aspartate kinase activity
NJU99_07900	COG0494	nUDIX hydrolase
NJU99_07905	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NJU99_07910	COG2890	protein-(glutamine-N5) methyltransferase activity
NJU99_07915	COG0339	signal peptide processing
NJU99_07930	COG0582	viral genome integration into host DNA
NJU99_07935	COG3706	GGDEF domain
NJU99_07940	COG2201	protein-glutamate methylesterase activity
NJU99_07945	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
NJU99_07950	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
NJU99_07955	COG0643	Histidine kinase
NJU99_07955	COG2198	Histidine kinase
NJU99_07960	COG0745	RESPONSE REGULATOR receiver
NJU99_07965	COG1185	polyribonucleotide nucleotidyltransferase activity
NJU99_07975	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
NJU99_07995	COG0659	secondary active sulfate transmembrane transporter activity
NJU99_08000	COG1160	GTP binding
NJU99_08010	COG1196	nuclear chromosome segregation
NJU99_08010	COG1674	ftsk spoiiie
NJU99_08015	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NJU99_08020	COG0440	acetolactate synthase activity
NJU99_08025	COG0028	Belongs to the TPP enzyme family
NJU99_08040	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NJU99_08045	COG3706	GGDEF domain
NJU99_08050	COG0659	secondary active sulfate transmembrane transporter activity
NJU99_08070	COG1683	Conserved Protein
NJU99_08075	COG0037	tRNA processing
NJU99_08085	COG0303	'Molybdopterin
NJU99_08095	COG1322	Protein conserved in bacteria
NJU99_08100	COG0501	Belongs to the peptidase M48B family
NJU99_08105	COG2199	diguanylate cyclase activity
NJU99_08115	COG0824	Thioesterase
NJU99_08155	COG0840	transmembrane signaling receptor activity
NJU99_08160	COG2199	diguanylate cyclase activity
NJU99_08160	COG2203	Gaf domain
NJU99_08165	COG0667	Aldo Keto reductase
NJU99_08180	COG1797	cobyrinic acid a,c-diamide synthase activity
NJU99_08195	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NJU99_08200	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
NJU99_08230	COG0840	transmembrane signaling receptor activity
NJU99_08240	COG4771	TonB-dependent receptor
NJU99_08250	COG0330	HflC and HflK could
NJU99_08260	COG0745	RESPONSE REGULATOR receiver
NJU99_08265	COG0840	transmembrane signaling receptor activity
NJU99_08270	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
NJU99_08275	COG0788	formyltetrahydrofolate deformylase activity
NJU99_08280	COG0280	phosphate acetyltransferase
NJU99_08280	COG0281	malic enzyme
NJU99_08285	COG1496	oxidoreductase activity
NJU99_08290	COG4106	trans-aconitate 2-methyltransferase activity
NJU99_08300	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NJU99_08330	COG2207	Transcriptional regulator
NJU99_08355	COG0754	glutathionylspermidine amidase activity
NJU99_08375	COG1663	tetraacyldisaccharide 4'-kinase activity
NJU99_08380	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NJU99_08385	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
NJU99_08405	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
NJU99_08410	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NJU99_08415	COG0805	protein transport
NJU99_08420	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NJU99_08430	COG0733	neurotransmitter:sodium symporter activity
NJU99_08450	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NJU99_08460	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
NJU99_08490	COG0419	ATPase involved in DNA repair
NJU99_08560	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NJU99_08590	COG4865	methylaspartate mutase activity
NJU99_08600	COG0318	PFAM AMP-dependent synthetase and ligase
NJU99_08605	COG2863	cytochrome
NJU99_08650	COG1595	DNA-templated transcription, initiation
NJU99_08670	COG0275	rRNA processing
NJU99_08680	COG0776	regulation of translation
NJU99_08685	COG0840	transmembrane signaling receptor activity
NJU99_08700	COG3279	Response regulator of the LytR AlgR family
NJU99_08705	COG3275	phosphorelay sensor kinase activity
NJU99_08710	COG1233	COG1233 Phytoene dehydrogenase and related
NJU99_08715	COG0415	Belongs to the DNA photolyase family
NJU99_08725	COG1643	Atp-dependent helicase
NJU99_08735	COG1283	sodium-dependent phosphate transmembrane transporter activity
NJU99_08745	COG5001	Diguanylate cyclase
NJU99_08745	COG5002	protein histidine kinase activity
NJU99_08750	COG0513	Belongs to the DEAD box helicase family
NJU99_08780	COG0642	Histidine kinase
NJU99_08785	COG0745	RESPONSE REGULATOR receiver
NJU99_08815	COG1132	(ABC) transporter
NJU99_08820	COG0628	permease
NJU99_08970	COG4626	Terminase
NJU99_08970	COG1802	Transcriptional regulator
NJU99_08995	COG0305	Participates in initiation and elongation during chromosome replication
NJU99_09080	COG0582	viral genome integration into host DNA
NJU99_09095	COG0653	protein targeting
NJU99_09100	COG4591	ABC-type transport system involved in lipoprotein release permease component
NJU99_09105	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NJU99_09105	COG4191	Histidine kinase
NJU99_09115	COG3437	response regulator, receiver
NJU99_09115	COG0784	Response regulator, receiver
NJU99_09125	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NJU99_09135	COG0039	L-malate dehydrogenase activity
NJU99_09165	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NJU99_09165	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
NJU99_09175	COG0484	heat shock protein binding
NJU99_09180	COG0789	Transcriptional regulator
NJU99_09185	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NJU99_09190	COG0849	cell division
NJU99_09200	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NJU99_09245	COG0768	penicillin binding
NJU99_09250	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
NJU99_09255	COG1338	Plays a role in the flagellum-specific transport system
NJU99_09265	COG1047	Peptidyl-prolyl cis-trans
NJU99_09275	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NJU99_09315	COG0218	Necessary for normal cell division and for the maintenance of normal septation
NJU99_09330	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
NJU99_09335	COG0131	Imidazoleglycerol-phosphate dehydratase
NJU99_09340	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NJU99_09345	COG0084	hydrolase, TatD family'
NJU99_09355	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NJU99_09360	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NJU99_09365	COG0359	binds to the 23S rRNA
NJU99_09370	COG0642	Histidine kinase
NJU99_09375	COG0745	RESPONSE REGULATOR receiver
NJU99_09390	COG0163	prenyltransferase activity
NJU99_09400	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NJU99_09405	COG0124	histidyl-tRNA synthetase
NJU99_09410	COG1166	arginine decarboxylase activity
NJU99_09415	COG1045	serine acetyltransferase
NJU99_09445	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NJU99_09455	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NJU99_09470	COG4536	flavin adenine dinucleotide binding
NJU99_09490	COG0628	permease
NJU99_09520	COG1028	Short-chain dehydrogenase reductase Sdr
NJU99_09525	COG5001	Diguanylate cyclase
NJU99_09525	COG5002	protein histidine kinase activity
NJU99_09535	COG2223	nitrite transmembrane transporter activity
NJU99_09550	COG3706	GGDEF domain
NJU99_09555	COG4191	Histidine kinase
NJU99_09560	COG2205	protein histidine kinase activity
NJU99_09560	COG4191	Histidine kinase
NJU99_09560	COG0745	RESPONSE REGULATOR receiver
NJU99_09585	COG1253	flavin adenine dinucleotide binding
NJU99_09590	COG2205	protein histidine kinase activity
NJU99_09610	COG2133	pyrroloquinoline quinone binding
NJU99_09615	COG0513	Belongs to the DEAD box helicase family
NJU99_09620	COG0596	Alpha beta hydrolase
NJU99_09630	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NJU99_09650	COG0596	Alpha beta hydrolase
NJU99_09680	COG1187	pseudouridine synthase activity
NJU99_09690	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
NJU99_09705	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NJU99_09710	COG0835	chemotaxis
NJU99_09710	COG0784	Response regulator, receiver
NJU99_09715	COG1187	pseudouridine synthase activity
NJU99_09740	COG0519	Catalyzes the synthesis of GMP from XMP
NJU99_09740	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NJU99_09745	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NJU99_09750	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
NJU99_09765	COG0436	Aminotransferase
NJU99_09770	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NJU99_09780	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
NJU99_09800	COG0488	(ABC) transporter
NJU99_09820	COG0527	aspartate kinase activity
NJU99_09825	COG0745	RESPONSE REGULATOR receiver
NJU99_09835	COG1917	Cupin 2, conserved barrel domain protein
NJU99_09840	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NJU99_09850	COG3706	GGDEF domain
NJU99_09855	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
NJU99_09865	COG1802	Transcriptional regulator
NJU99_09885	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NJU99_09895	COG1012	belongs to the aldehyde dehydrogenase family
NJU99_09915	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NJU99_09920	COG0488	(ABC) transporter
NJU99_09945	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
NJU99_09990	COG0300	oxidoreductase activity
NJU99_09995	COG1757	Na H antiporter
NJU99_10010	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
NJU99_10020	COG0446	pyridine nucleotide-disulphide oxidoreductase
NJU99_10030	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NJU99_10035	COG0742	ribosomal rna small subunit methyltransferase
NJU99_10040	COG1418	mRNA catabolic process
NJU99_10050	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NJU99_10055	COG0552	protein localization to endoplasmic reticulum
NJU99_10075	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NJU99_10080	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NJU99_10095	COG1592	Rubrerythrin
NJU99_10100	COG1592	Rubrerythrin
NJU99_10110	COG0728	peptidoglycan biosynthetic process
NJU99_10115	COG1132	(ABC) transporter
NJU99_10120	COG0167	dihydroorotate dehydrogenase activity
NJU99_10135	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NJU99_10140	COG1028	Short-chain dehydrogenase reductase Sdr
NJU99_10145	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NJU99_10150	COG0750	zinc metalloprotease
NJU99_10155	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NJU99_10160	COG0134	indole-3-glycerol-phosphate synthase activity
NJU99_10170	COG0727	PFAM Uncharacterised protein family (UPF0153)
NJU99_10175	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
NJU99_10185	COG0674	pyruvate-flavodoxin oxidoreductase activity
NJU99_10185	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
NJU99_10190	COG1013	pyruvate-flavodoxin oxidoreductase activity
NJU99_10200	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NJU99_10205	COG2176	DNA-directed DNA polymerase activity
NJU99_10210	COG0135	phosphoribosylanthranilate isomerase activity
NJU99_10215	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NJU99_10235	COG0642	Histidine kinase
NJU99_10240	COG0745	RESPONSE REGULATOR receiver
NJU99_10250	COG1666	GTP binding
NJU99_10255	COG2233	PERMEase
NJU99_10260	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NJU99_10275	COG2363	Small membrane protein
NJU99_10285	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
NJU99_10290	COG2252	PERMEase
NJU99_10295	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NJU99_10340	COG0731	radical SAM domain protein
NJU99_10345	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NJU99_10355	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NJU99_10370	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NJU99_10375	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NJU99_10380	COG0227	Belongs to the bacterial ribosomal protein bL28 family
NJU99_10395	COG0463	Glycosyl transferase, family 2
NJU99_10400	COG0726	polysaccharide deacetylase
NJU99_10405	COG0438	transferase activity, transferring glycosyl groups
NJU99_10420	COG0726	polysaccharide deacetylase
NJU99_10450	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
NJU99_10460	COG0493	'glutamate synthase
NJU99_10465	COG0069	glutamate synthase activity
NJU99_10465	COG0070	glutamate synthase
NJU99_10465	COG0067	glutamate synthase
NJU99_10500	COG2205	protein histidine kinase activity
NJU99_10500	COG0784	Response regulator, receiver
NJU99_10505	COG0697	spore germination
NJU99_10510	COG1012	belongs to the aldehyde dehydrogenase family
NJU99_10530	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
NJU99_10535	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NJU99_10560	COG0745	RESPONSE REGULATOR receiver
NJU99_10565	COG0745	RESPONSE REGULATOR receiver
NJU99_10580	COG1136	(ABC) transporter
NJU99_10625	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NJU99_10630	COG1115	amino acid carrier protein
NJU99_10635	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NJU99_10640	COG0251	oxidation-reduction process
NJU99_10645	COG2964	Protein conserved in bacteria
NJU99_10680	COG2197	response regulator
NJU99_10735	COG0604	alcohol dehydrogenase
NJU99_10740	COG2113	Glycine betaine
NJU99_10745	COG4176	ABC-type proline glycine betaine transport system permease component
NJU99_10750	COG4175	Glycine betaine
NJU99_10755	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NJU99_10760	COG2205	protein histidine kinase activity
NJU99_10835	COG3706	GGDEF domain
NJU99_10840	COG0284	orotidine-5'-phosphate decarboxylase activity
NJU99_10845	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NJU99_10850	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
NJU99_10870	COG0067	glutamate synthase
NJU99_10870	COG0069	glutamate synthase activity
NJU99_10870	COG0070	glutamate synthase
NJU99_10880	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NJU99_10945	COG1459	type II secretion system
NJU99_10960	COG1739	Uncharacterized protein family UPF0029
NJU99_10990	COG2226	methyltransferase
NJU99_10995	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NJU99_11005	COG0277	FAD linked oxidase domain protein
NJU99_11060	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NJU99_11075	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NJU99_11080	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NJU99_11085	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
NJU99_11105	COG0438	transferase activity, transferring glycosyl groups
NJU99_11125	COG0463	Glycosyl transferase, family 2
NJU99_11125	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NJU99_11130	COG0438	transferase activity, transferring glycosyl groups
NJU99_11145	COG0489	protein tyrosine kinase activity
NJU99_11145	COG3206	protein involved in exopolysaccharide biosynthesis
NJU99_11160	COG2201	protein-glutamate methylesterase activity
NJU99_11165	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NJU99_11170	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
NJU99_11175	COG1047	Peptidyl-prolyl cis-trans
NJU99_11190	COG0823	Involved in the tonB-independent uptake of proteins
NJU99_11200	COG0848	biopolymer transport protein
NJU99_11205	COG0811	peptide transport
NJU99_11210	COG0355	proton-transporting ATP synthase activity, rotational mechanism
NJU99_11215	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NJU99_11220	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NJU99_11225	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NJU99_11230	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NJU99_11235	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NJU99_11245	COG1475	DNA binding
NJU99_11250	COG1192	Involved in chromosome partitioning
NJU99_11255	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
NJU99_11255	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
NJU99_11265	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NJU99_11270	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NJU99_11275	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NJU99_11280	COG0211	Belongs to the bacterial ribosomal protein bL27 family
NJU99_11285	COG0261	This protein binds to 23S rRNA in the presence of protein L20
NJU99_11295	COG0358	DNA primase activity
NJU99_11305	COG0328	RNA-DNA hybrid ribonuclease activity
NJU99_11310	COG0571	ribonuclease III activity
NJU99_11315	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NJU99_11320	COG0501	Belongs to the peptidase M48B family
NJU99_11330	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NJU99_11340	COG0706	membrane insertase activity
NJU99_11345	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
NJU99_11350	COG0230	Belongs to the bacterial ribosomal protein bL34 family
NJU99_11355	COG4191	Histidine kinase
NJU99_11360	COG0542	response to heat
NJU99_11380	COG5002	protein histidine kinase activity
NJU99_11385	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NJU99_11415	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NJU99_11420	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NJU99_11425	COG0179	Fumarylacetoacetate (FAA) hydrolase
NJU99_11455	COG2855	membrane
NJU99_11460	COG0583	DNA-binding transcription factor activity
NJU99_11475	COG0297	glycogen (starch) synthase activity
NJU99_11475	COG0438	transferase activity, transferring glycosyl groups
NJU99_11485	COG0138	bifunctional purine biosynthesis protein purh
NJU99_11490	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NJU99_11500	COG0739	heme binding
NJU99_11505	COG2239	Acts as a magnesium transporter
NJU99_11535	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NJU99_11540	COG0606	chelatase, subunit chli
NJU99_11550	COG0840	transmembrane signaling receptor activity
NJU99_11560	COG0242	peptide deformylase activity
NJU99_11565	COG0740	serine-type endopeptidase activity
NJU99_11570	COG0544	peptidyl-prolyl cis-trans isomerase activity
NJU99_11575	COG2304	oxidoreductase activity
NJU99_11580	COG2326	polyphosphate kinase activity
NJU99_11595	COG1773	rubredoxin
NJU99_11655	COG1858	cytochrome C peroxidase
NJU99_11690	COG0716	FMN binding
NJU99_11740	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
NJU99_11745	COG3706	GGDEF domain
NJU99_11770	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
NJU99_11775	COG0159	tryptophan synthase activity
NJU99_11780	COG3852	Histidine kinase
NJU99_11785	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
NJU99_11790	COG2255	four-way junction helicase activity
NJU99_11795	COG0628	permease
NJU99_11800	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NJU99_11805	COG0095	Lipoate-protein ligase
NJU99_11810	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
NJU99_11815	COG0508	dehydrogenase complex catalyzes the overall conversion of
NJU99_11820	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NJU99_11865	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
NJU99_11870	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
NJU99_11885	COG0542	response to heat
NJU99_11890	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
NJU99_11895	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
NJU99_11905	COG0318	PFAM AMP-dependent synthetase and ligase
NJU99_11910	COG2030	dehydratase
NJU99_11930	COG0840	transmembrane signaling receptor activity
NJU99_11940	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NJU99_11945	COG4191	Histidine kinase
NJU99_11975	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NJU99_11980	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NJU99_11985	COG1157	protein secretion by the type III secretion system
NJU99_11995	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NJU99_12015	COG1677	Flagellar hook-basal body complex protein FliE
NJU99_12025	COG0455	bacterial-type flagellum organization
NJU99_12030	COG1419	protein localization to endoplasmic reticulum
NJU99_12045	COG3951	Flagellar rod assembly protein muramidase FlgJ
NJU99_12055	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
NJU99_12080	COG1749	Flagellar hook protein flgE
NJU99_12105	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NJU99_12110	COG1766	The M ring may be actively involved in energy transduction
NJU99_12115	COG1815	bacterial-type flagellum-dependent cell motility
NJU99_12120	COG4786	Flagellar basal body rod
NJU99_12130	COG0745	RESPONSE REGULATOR receiver
NJU99_12150	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NJU99_12160	COG0228	four-way junction DNA binding
NJU99_12165	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NJU99_12170	COG0564	pseudouridine synthase activity
NJU99_12175	COG1519	Transferase
NJU99_12185	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NJU99_12190	COG0752	glycyl-tRNA synthetase alpha subunit
NJU99_12200	COG0826	peptidase U32
NJU99_12205	COG0840	transmembrane signaling receptor activity
NJU99_12210	COG2770	Histidine kinase
NJU99_12210	COG3437	response regulator, receiver
NJU99_12250	COG3258	Cytochrome c
NJU99_12275	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NJU99_12280	COG0497	DNA recombination
NJU99_12285	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NJU99_12290	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NJU99_12295	COG0049	tRNA binding
NJU99_12300	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NJU99_12305	COG1671	Belongs to the UPF0178 family
NJU99_12310	COG4895	conserved protein (DUF2196)
NJU99_12320	COG0038	chloride channel
NJU99_12325	COG2199	diguanylate cyclase activity
NJU99_12380	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NJU99_12385	COG0085	RNA polymerase activity
NJU99_12390	COG0222	ribosome binding
NJU99_12395	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NJU99_12400	COG0081	regulation of translation
NJU99_12405	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NJU99_12410	COG0250	Participates in transcription elongation, termination and antitermination
NJU99_12425	COG0267	Belongs to the bacterial ribosomal protein bL33 family
NJU99_12430	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NJU99_12460	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NJU99_12465	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NJU99_12470	COG0444	Belongs to the ABC transporter superfamily
NJU99_12475	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
NJU99_12480	COG0174	glutamine synthetase
NJU99_12490	COG0314	molybdopterin synthase activity
NJU99_12500	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
NJU99_12505	COG1968	undecaprenyl-diphosphatase activity
NJU99_12515	COG0772	Belongs to the SEDS family
NJU99_12525	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NJU99_12570	COG0512	Glutamine amidotransferase of anthranilate synthase
NJU99_12575	COG1840	ABC-type Fe3 transport system, periplasmic component
NJU99_12585	COG3842	ATPase activity
NJU99_12595	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
NJU99_12600	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
NJU99_12605	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NJU99_12610	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NJU99_12615	COG0649	NAD binding
NJU99_12615	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NJU99_12630	COG0372	Belongs to the citrate synthase family
NJU99_12635	COG1034	ATP synthesis coupled electron transport
NJU99_12640	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
NJU99_12645	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NJU99_12650	COG0839	Belongs to the complex I subunit 6 family
NJU99_12655	COG0713	ATP synthesis coupled electron transport
NJU99_12660	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NJU99_12670	COG1007	ATP synthesis coupled electron transport
NJU99_12680	COG1053	succinate dehydrogenase
NJU99_12685	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NJU99_12695	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
NJU99_12705	COG1451	nucleotide metabolic process
NJU99_12730	COG0189	ligase activity
NJU99_12745	COG2183	response to ionizing radiation
NJU99_12755	COG0251	oxidation-reduction process
NJU99_12770	COG2095	MarC family integral membrane protein
NJU99_12775	COG0765	amino acid transport
NJU99_12785	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NJU99_12825	COG3852	Histidine kinase
NJU99_12830	COG0318	PFAM AMP-dependent synthetase and ligase
NJU99_12835	COG3246	L-lysine catabolic process to acetate
NJU99_12840	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NJU99_12840	COG0189	ligase activity
NJU99_12845	COG1028	Short-chain dehydrogenase reductase Sdr
NJU99_12850	COG0318	PFAM AMP-dependent synthetase and ligase
NJU99_12865	COG0500	methyltransferase
NJU99_12875	COG0601	transmembrane transport
NJU99_12890	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NJU99_12895	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NJU99_12900	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NJU99_12905	COG0514	ATP-dependent DNA helicase (RecQ)
NJU99_12915	COG1280	lysine exporter protein (LysE YggA)
NJU99_12935	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NJU99_12940	COG2828	Protein conserved in bacteria
NJU99_12950	COG1879	ABC-type sugar transport system periplasmic component
NJU99_12955	COG1335	isochorismatase
NJU99_12960	COG2824	Alkylphosphonate utilization operon protein PhnA
NJU99_12965	COG0181	hydroxymethylbilane synthase activity
NJU99_12980	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
NJU99_12995	COG2011	ABC-type metal ion transport system permease component
NJU99_13000	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NJU99_13005	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NJU99_13010	COG0450	alkyl hydroperoxide reductase
NJU99_13020	COG0105	UTP biosynthetic process
NJU99_13030	COG0333	Belongs to the bacterial ribosomal protein bL32 family
NJU99_13035	COG0416	fatty acid biosynthetic process
NJU99_13040	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NJU99_13050	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
NJU99_13065	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NJU99_13080	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NJU99_13085	COG0540	Belongs to the ATCase OTCase family
NJU99_13090	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NJU99_13105	COG0469	pyruvate kinase activity
NJU99_13110	COG2885	chlorophyll binding
NJU99_13120	COG0642	Histidine kinase
NJU99_13125	COG0745	RESPONSE REGULATOR receiver
NJU99_13130	COG2104	thiamine diphosphate biosynthetic process
NJU99_13135	COG0792	nuclease activity
NJU99_13140	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NJU99_13140	COG0475	glutathione-regulated potassium exporter activity
NJU99_13145	COG0840	transmembrane signaling receptor activity
NJU99_13160	COG0156	8-amino-7-oxononanoate synthase activity
NJU99_13165	COG0288	reversible hydration of carbon dioxide
NJU99_13175	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
NJU99_13185	COG2121	Domain of unknown function (DUF374)
NJU99_13190	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NJU99_13200	COG0195	Participates in both transcription termination and antitermination
NJU99_13205	COG0215	cysteine-tRNA ligase activity
NJU99_13210	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NJU99_13220	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NJU99_13225	COG0629	single-stranded DNA binding
NJU99_13230	COG0360	Binds together with S18 to 16S ribosomal RNA
NJU99_13240	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
NJU99_13245	COG0557	exoribonuclease II activity
NJU99_13250	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NJU99_13350	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NJU99_13365	COG0436	Aminotransferase
NJU99_13390	COG2201	protein-glutamate methylesterase activity
NJU99_13395	COG0343	queuine tRNA-ribosyltransferase activity
NJU99_13425	COG4962	Type ii secretion system protein e
NJU99_13445	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NJU99_13455	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
NJU99_13465	COG0560	Phosphoserine phosphatase
NJU99_13470	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NJU99_13475	COG0736	holo-[acyl-carrier-protein] synthase activity
NJU99_13495	COG1846	Transcriptional regulator
NJU99_13500	COG2153	protein acetylation
NJU99_13505	COG0601	transmembrane transport
NJU99_13510	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NJU99_13515	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NJU99_13580	COG1706	bacterial-type flagellum-dependent cell motility
NJU99_13585	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NJU99_13590	COG0418	dihydroorotase activity
NJU99_13600	COG0004	ammonium transporteR
NJU99_13610	COG0004	ammonium transporteR
NJU99_13615	COG0840	transmembrane signaling receptor activity
NJU99_13620	COG2200	EAL domain
NJU99_13640	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
NJU99_13680	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NJU99_13685	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NJU99_13695	COG0640	Transcriptional regulator
NJU99_13705	COG1346	cytolysis
NJU99_13735	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NJU99_13745	COG2815	serine threonine protein kinase
NJU99_13745	COG0515	serine threonine protein kinase
NJU99_13790	COG4753	response regulator
NJU99_13790	COG2207	Transcriptional regulator
NJU99_13795	COG4191	Histidine kinase
NJU99_13800	COG0604	alcohol dehydrogenase
NJU99_13820	COG0129	dihydroxy-acid dehydratase activity
NJU99_13825	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NJU99_13830	COG0745	RESPONSE REGULATOR receiver
NJU99_13835	COG0642	Histidine kinase
NJU99_13850	COG1492	cobalamin metabolic process
NJU99_13865	COG0745	RESPONSE REGULATOR receiver
NJU99_13885	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
NJU99_13895	COG1490	D-aminoacyl-tRNA deacylase activity
NJU99_13905	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NJU99_13920	COG2095	MarC family integral membrane protein
NJU99_13925	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
NJU99_13930	COG4232	protein-disulfide reductase activity
NJU99_13935	COG3118	belongs to the thioredoxin family
NJU99_13940	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NJU99_13950	COG5001	Diguanylate cyclase
NJU99_13950	COG4251	negative regulation of phosphorylation
NJU99_13950	COG3706	GGDEF domain
NJU99_13950	COG2203	Gaf domain
NJU99_13955	COG0688	phosphatidylethanolamine metabolic process
NJU99_13960	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
NJU99_13975	COG0443	Heat shock 70 kDa protein
NJU99_13980	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NJU99_13990	COG2358	TRAP transporter, solute receptor (TAXI family
NJU99_14000	COG2204	response regulator
NJU99_14005	COG4191	Histidine kinase
NJU99_14010	COG0101	tRNA pseudouridine synthase activity
NJU99_14020	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
NJU99_14025	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NJU99_14035	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NJU99_14045	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NJU99_14050	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NJU99_14065	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NJU99_14080	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NJU99_14105	COG2089	acid synthase
NJU99_14135	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
NJU99_14140	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NJU99_14145	COG1086	Polysaccharide biosynthesis protein
NJU99_14150	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
NJU99_14165	COG3959	Transketolase, thiamine diphosphate binding domain
NJU99_14170	COG3958	Transketolase
NJU99_14190	COG2226	methyltransferase
NJU99_14195	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NJU99_14215	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NJU99_14225	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NJU99_14230	COG0148	phosphopyruvate hydratase activity
NJU99_14245	COG0569	domain protein
NJU99_14245	COG0475	glutathione-regulated potassium exporter activity
NJU99_14250	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NJU99_14270	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
NJU99_14280	COG1007	ATP synthesis coupled electron transport
NJU99_14290	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NJU99_14295	COG0713	ATP synthesis coupled electron transport
NJU99_14300	COG0839	Belongs to the complex I subunit 6 family
NJU99_14305	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NJU99_14310	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
NJU99_14315	COG1034	ATP synthesis coupled electron transport
NJU99_14330	COG0649	NAD binding
NJU99_14335	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NJU99_14340	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NJU99_14345	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NJU99_14350	COG0840	transmembrane signaling receptor activity
NJU99_14360	COG1222	aaa ATPase
NJU99_14385	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NJU99_14390	COG1252	NADH dehydrogenase
NJU99_14400	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NJU99_14410	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NJU99_14415	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NJU99_14420	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NJU99_14440	COG0445	tRNA wobble uridine modification
NJU99_14450	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NJU99_14465	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
NJU99_14475	COG0348	domain, Protein
NJU99_14480	COG0504	CTP synthase activity
NJU99_14485	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
NJU99_14510	COG0587	DNA-directed DNA polymerase activity
NJU99_14515	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
NJU99_14540	COG0315	cyclic pyranopterin monophosphate synthase activity
NJU99_14545	COG0828	Belongs to the bacterial ribosomal protein bS21 family
NJU99_14595	COG0670	Belongs to the BI1 family
NJU99_14600	COG0352	thiamine-phosphate diphosphorylase activity
NJU99_14610	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NJU99_14620	COG0233	cytoplasmic translational termination
NJU99_14625	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NJU99_14630	COG1714	RDD family
NJU99_14635	COG2814	Major facilitator Superfamily
NJU99_14640	COG0840	transmembrane signaling receptor activity
NJU99_14655	COG3022	response to hydroperoxide
NJU99_14690	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NJU99_14695	COG1012	belongs to the aldehyde dehydrogenase family
NJU99_14705	COG0546	phosphoglycolate phosphatase activity
NJU99_14720	COG2814	Major facilitator Superfamily
NJU99_14740	COG0415	Belongs to the DNA photolyase family
NJU99_14775	COG2081	HI0933 family
NJU99_14790	COG1959	2 iron, 2 sulfur cluster binding
NJU99_14805	COG0175	sulfate reduction
NJU99_14810	COG0175	sulfate reduction
NJU99_14815	COG2895	sulfate adenylyltransferase (ATP) activity
NJU99_14825	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NJU99_14830	COG1408	metallophosphoesterase
NJU99_14835	COG0840	transmembrane signaling receptor activity
NJU99_14840	COG0840	transmembrane signaling receptor activity
NJU99_14840	COG3290	protein histidine kinase activity
NJU99_14855	COG1217	gtp-binding protein TYPA
NJU99_14860	COG2066	Belongs to the glutaminase family
NJU99_14865	COG2860	membrane
NJU99_14880	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NJU99_14885	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group