locus-tag	class	description
ABLL_0001	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ABLL_0002	COG0592	DNA-directed DNA polymerase activity
ABLL_0003	COG0187	DNA topoisomerase II activity
ABLL_0004	COG0492	ferredoxin-NADP+ reductase activity
ABLL_0005	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ABLL_0007	COG1238	metal cluster binding
ABLL_0009	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ABLL_0014	COG1053	succinate dehydrogenase
ABLL_0015	COG0667	Aldo Keto reductase
ABLL_0018	COG4208	sulfate ABC transporter
ABLL_0021	COG0500	methyltransferase
ABLL_0022	COG1120	ATPase activity
ABLL_0032	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
ABLL_0034	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
ABLL_0038	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
ABLL_0043	COG0716	FMN binding
ABLL_0051	COG0531	amino acid
ABLL_0055	COG2249	NAD(P)H dehydrogenase (quinone) activity
ABLL_0056	COG1733	regulation of RNA biosynthetic process
ABLL_0060	COG0426	domain, Protein
ABLL_0063	COG1280	lysine exporter protein (LysE YggA)
ABLL_0069	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ABLL_0076	COG0840	transmembrane signaling receptor activity
ABLL_0077	COG0564	pseudouridine synthase activity
ABLL_0078	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ABLL_0079	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ABLL_0080	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ABLL_0088	COG1151	hydroxylamine reductase activity
ABLL_0091	COG2885	chlorophyll binding
ABLL_0092	COG0052	Belongs to the universal ribosomal protein uS2 family
ABLL_0093	COG0604	alcohol dehydrogenase
ABLL_0094	COG1733	regulation of RNA biosynthetic process
ABLL_0095	COG0390	transport system, permease component
ABLL_0097	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ABLL_0098	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ABLL_0103	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ABLL_0104	COG1252	NADH dehydrogenase
ABLL_0105	COG2030	dehydratase
ABLL_0106	COG0659	secondary active sulfate transmembrane transporter activity
ABLL_0107	COG1960	acyl-CoA dehydrogenase activity
ABLL_0108	COG2181	nitrate reductase activity
ABLL_0108	COG0247	lactate metabolic process
ABLL_0110	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
ABLL_0111	COG0500	methyltransferase
ABLL_0112	COG1250	3-hydroxyacyl-CoA dehydrogenase
ABLL_0113	COG2050	protein possibly involved in aromatic compounds catabolism
ABLL_0114	COG0824	Thioesterase
ABLL_0117	COG0183	Belongs to the thiolase family
ABLL_0118	COG5002	protein histidine kinase activity
ABLL_0119	COG0745	RESPONSE REGULATOR receiver
ABLL_0120	COG0745	RESPONSE REGULATOR receiver
ABLL_0121	COG3852	Histidine kinase
ABLL_0122	COG1556	Lactate utilization protein
ABLL_0123	COG1139	Iron-sulfur cluster binding protein
ABLL_0124	COG0247	lactate metabolic process
ABLL_0126	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ABLL_0127	COG0511	ligase activity, forming carbon-carbon bonds
ABLL_0128	COG0439	Biotin carboxylase
ABLL_0129	COG0513	Belongs to the DEAD box helicase family
ABLL_0130	COG0306	phosphate transporter
ABLL_0132	COG0367	asparagine synthase
ABLL_0134	COG0778	Nitroreductase
ABLL_0135	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ABLL_0137	COG1053	succinate dehydrogenase
ABLL_0139	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ABLL_0141	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ABLL_0141	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
ABLL_0142	COG1187	pseudouridine synthase activity
ABLL_0143	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ABLL_0143	COG0517	IMP dehydrogenase activity
ABLL_0144	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ABLL_0145	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ABLL_0146	COG0107	imidazoleglycerol-phosphate synthase activity
ABLL_0149	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ABLL_0150	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ABLL_0151	COG0724	RNA recognition motif
ABLL_0152	COG0745	RESPONSE REGULATOR receiver
ABLL_0160	COG0534	Mate efflux family protein
ABLL_0161	COG0789	Transcriptional regulator
ABLL_0162	COG1335	isochorismatase
ABLL_0163	COG0460	homoserine dehydrogenase
ABLL_0164	COG0436	Aminotransferase
ABLL_0167	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ABLL_0168	COG0254	rRNA binding
ABLL_0169	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ABLL_0186	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
ABLL_0188	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ABLL_0189	COG0237	dephospho-CoA kinase activity
ABLL_0190	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
ABLL_0191	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ABLL_0192	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ABLL_0196	COG2353	YceI-like domain
ABLL_0197	COG1846	Transcriptional regulator
ABLL_0198	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ABLL_0199	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
ABLL_0200	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ABLL_0202	COG0505	Belongs to the CarA family
ABLL_0203	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ABLL_0205	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ABLL_0205	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ABLL_0208	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ABLL_0209	COG0489	protein tyrosine kinase activity
ABLL_0211	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ABLL_0211	COG0140	phosphoribosyl-ATP diphosphatase activity
ABLL_0216	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ABLL_0218	COG0646	methionine synthase
ABLL_0218	COG1410	methionine synthase
ABLL_0219	COG0697	spore germination
ABLL_0221	COG1979	alcohol dehydrogenase
ABLL_0222	COG3647	Membrane
ABLL_0225	COG1686	Belongs to the peptidase S11 family
ABLL_0228	COG1854	S-ribosylhomocysteine lyase activity
ABLL_0235	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ABLL_0240	COG1013	pyruvate-flavodoxin oxidoreductase activity
ABLL_0241	COG0674	pyruvate-flavodoxin oxidoreductase activity
ABLL_0243	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ABLL_0244	COG0546	phosphoglycolate phosphatase activity
ABLL_0246	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ABLL_0247	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ABLL_0248	COG5002	protein histidine kinase activity
ABLL_0251	COG0704	Plays a role in the regulation of phosphate uptake
ABLL_0252	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ABLL_0253	COG0581	inorganic phosphate transmembrane transporter activity
ABLL_0254	COG0573	inorganic phosphate transmembrane transporter activity
ABLL_0255	COG2200	EAL domain
ABLL_0255	COG2199	diguanylate cyclase activity
ABLL_0255	COG2203	Gaf domain
ABLL_0256	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ABLL_0258	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ABLL_0259	COG0268	Binds directly to 16S ribosomal RNA
ABLL_0260	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ABLL_0262	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ABLL_0265	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ABLL_0266	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ABLL_0267	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ABLL_0268	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ABLL_0274	COG0575	Belongs to the CDS family
ABLL_0275	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ABLL_0279	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ABLL_0280	COG0023	Translation Initiation Factor
ABLL_0281	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ABLL_0281	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ABLL_0282	COG1324	tolerance protein
ABLL_0283	COG2022	thiamine diphosphate biosynthetic process
ABLL_0288	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
ABLL_0298	COG0745	RESPONSE REGULATOR receiver
ABLL_0301	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ABLL_0304	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ABLL_0306	COG2084	Dehydrogenase
ABLL_0309	COG1346	cytolysis
ABLL_0310	COG0640	Transcriptional regulator
ABLL_0312	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ABLL_0313	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ABLL_0317	COG0659	secondary active sulfate transmembrane transporter activity
ABLL_0321	COG4589	Belongs to the CDS family
ABLL_0325	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
ABLL_0330	COG0666	response to abiotic stimulus
ABLL_0331	COG0004	ammonium transporteR
ABLL_0333	COG0004	ammonium transporteR
ABLL_0335	COG0418	dihydroorotase activity
ABLL_0337	COG1706	bacterial-type flagellum-dependent cell motility
ABLL_0344	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
ABLL_0346	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
ABLL_0349	COG0037	tRNA processing
ABLL_0350	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ABLL_0351	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ABLL_0352	COG0601	transmembrane transport
ABLL_0354	COG0736	holo-[acyl-carrier-protein] synthase activity
ABLL_0355	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ABLL_0357	COG0560	Phosphoserine phosphatase
ABLL_0359	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
ABLL_0360	COG3248	Nucleoside-binding outer membrane protein
ABLL_0362	COG1393	Belongs to the ArsC family
ABLL_0363	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ABLL_0364	COG0343	queuine tRNA-ribosyltransferase activity
ABLL_0366	COG0436	Aminotransferase
ABLL_0369	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ABLL_0371	COG2861	carbohydrate metabolic process
ABLL_0372	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ABLL_0373	COG0557	exoribonuclease II activity
ABLL_0376	COG0360	Binds together with S18 to 16S ribosomal RNA
ABLL_0377	COG0629	single-stranded DNA binding
ABLL_0378	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ABLL_0379	COG0215	cysteine-tRNA ligase activity
ABLL_0380	COG0195	Participates in both transcription termination and antitermination
ABLL_0382	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ABLL_0383	COG2121	Domain of unknown function (DUF374)
ABLL_0385	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
ABLL_0387	COG0288	reversible hydration of carbon dioxide
ABLL_0388	COG0156	8-amino-7-oxononanoate synthase activity
ABLL_0389	COG0792	nuclease activity
ABLL_0395	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ABLL_0397	COG0540	Belongs to the ATCase OTCase family
ABLL_0398	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ABLL_0402	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
ABLL_0403	COG1687	branched-chain amino acid
ABLL_0404	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ABLL_0405	COG0416	fatty acid biosynthetic process
ABLL_0406	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ABLL_0408	COG0105	UTP biosynthetic process
ABLL_0410	COG0450	alkyl hydroperoxide reductase
ABLL_0411	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ABLL_0413	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ABLL_0414	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ABLL_0415	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ABLL_0417	COG0181	hydroxymethylbilane synthase activity
ABLL_0419	COG3706	GGDEF domain
ABLL_0419	COG0745	RESPONSE REGULATOR receiver
ABLL_0420	COG2828	Protein conserved in bacteria
ABLL_0421	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ABLL_0423	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
ABLL_0425	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ABLL_0433	COG0514	ATP-dependent DNA helicase (RecQ)
ABLL_0435	COG0640	Transcriptional regulator
ABLL_0436	COG2217	Heavy metal translocating P-type atpase
ABLL_0439	COG1451	nucleotide metabolic process
ABLL_0440	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
ABLL_0442	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ABLL_0443	COG1053	succinate dehydrogenase
ABLL_0445	COG1007	ATP synthesis coupled electron transport
ABLL_0447	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ABLL_0448	COG0713	ATP synthesis coupled electron transport
ABLL_0449	COG0839	Belongs to the complex I subunit 6 family
ABLL_0450	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ABLL_0451	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ABLL_0452	COG1034	ATP synthesis coupled electron transport
ABLL_0453	COG0372	Belongs to the citrate synthase family
ABLL_0456	COG0649	NAD binding
ABLL_0456	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ABLL_0457	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ABLL_0458	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ABLL_0459	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ABLL_0460	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ABLL_0461	COG3610	response to peptide
ABLL_0462	COG2966	Psort location CytoplasmicMembrane, score
ABLL_0464	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
ABLL_0465	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ABLL_0469	COG0784	Response regulator, receiver
ABLL_0469	COG5002	protein histidine kinase activity
ABLL_0469	COG2205	protein histidine kinase activity
ABLL_0470	COG3920	Histidine kinase
ABLL_0471	COG3706	GGDEF domain
ABLL_0472	COG0180	Tryptophanyl-tRNA synthetase
ABLL_0475	COG4771	TonB-dependent receptor
ABLL_0481	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ABLL_0485	COG0840	transmembrane signaling receptor activity
ABLL_0489	COG3043	anaerobic respiration
ABLL_0490	COG0348	domain, Protein
ABLL_0491	COG0437	4 iron, 4 sulfur cluster binding
ABLL_0492	COG0243	molybdopterin cofactor binding
ABLL_0493	COG3287	FIST C domain
ABLL_0493	COG2199	diguanylate cyclase activity
ABLL_0493	COG2200	EAL domain
ABLL_0494	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ABLL_0497	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ABLL_0498	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ABLL_0499	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ABLL_0501	COG2404	hydrolase activity, acting on ester bonds
ABLL_0502	COG1832	CoA-binding protein
ABLL_0503	COG0642	Histidine kinase
ABLL_0504	COG0745	RESPONSE REGULATOR receiver
ABLL_0505	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ABLL_0506	COG0191	fructose-bisphosphate aldolase activity
ABLL_0512	COG0811	peptide transport
ABLL_0514	COG4191	Histidine kinase
ABLL_0517	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ABLL_0519	COG0142	geranyltranstransferase activity
ABLL_0520	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ABLL_0521	COG0442	prolyl-tRNA aminoacylation
ABLL_0522	COG0668	transmembrane transport
ABLL_0526	COG0815	Transfers the fatty acyl group on membrane lipoproteins
ABLL_0527	COG1862	Preprotein translocase
ABLL_0528	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ABLL_0529	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ABLL_0532	COG0495	leucyl-tRNA aminoacylation
ABLL_0534	COG0285	dihydrofolate synthase activity
ABLL_0541	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
ABLL_0545	COG4399	Belongs to the UPF0754 family
ABLL_0548	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ABLL_0553	COG5001	Diguanylate cyclase
ABLL_0553	COG4251	negative regulation of phosphorylation
ABLL_0553	COG3706	GGDEF domain
ABLL_0553	COG2203	Gaf domain
ABLL_0556	COG0745	RESPONSE REGULATOR receiver
ABLL_0557	COG0642	Histidine kinase
ABLL_0558	COG2081	HI0933 family
ABLL_0559	COG0840	transmembrane signaling receptor activity
ABLL_0561	COG0840	transmembrane signaling receptor activity
ABLL_0563	COG1692	metallophosphoesterase
ABLL_0566	COG2226	methyltransferase
ABLL_0567	COG1570	exodeoxyribonuclease VII activity
ABLL_0569	COG2204	response regulator
ABLL_0570	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ABLL_0572	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
ABLL_0573	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ABLL_0575	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ABLL_0576	COG0459	protein refolding
ABLL_0577	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
ABLL_0579	COG0745	RESPONSE REGULATOR receiver
ABLL_0580	COG1408	metallophosphoesterase
ABLL_0585	COG1136	(ABC) transporter
ABLL_0588	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ABLL_0592	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ABLL_0593	COG0352	thiamine-phosphate diphosphorylase activity
ABLL_0594	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ABLL_0596	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ABLL_0597	COG2264	protein methyltransferase activity
ABLL_0598	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ABLL_0599	COG0784	Response regulator, receiver
ABLL_0599	COG3437	response regulator, receiver
ABLL_0600	COG0784	Response regulator, receiver
ABLL_0600	COG4191	Histidine kinase
ABLL_0601	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ABLL_0605	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ABLL_0611	COG1132	(ABC) transporter
ABLL_0614	COG3706	GGDEF domain
ABLL_0615	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ABLL_0616	COG1090	epimerase
ABLL_0617	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ABLL_0620	COG0481	GTPase activity
ABLL_0623	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ABLL_0625	COG0482	sulfurtransferase activity
ABLL_0626	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ABLL_0627	COG0006	proline dipeptidase activity
ABLL_0628	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ABLL_0629	COG0402	S-adenosylhomocysteine deaminase activity
ABLL_0630	COG0616	signal peptide processing
ABLL_0632	COG0280	phosphate acetyltransferase
ABLL_0633	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ABLL_0634	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ABLL_0635	COG2176	DNA-directed DNA polymerase activity
ABLL_0639	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ABLL_0641	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
ABLL_0643	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ABLL_0645	COG0745	RESPONSE REGULATOR receiver
ABLL_0646	COG5002	protein histidine kinase activity
ABLL_0647	COG1546	Belongs to the CinA family
ABLL_0647	COG1058	Belongs to the CinA family
ABLL_0648	COG0579	oxidoreductase
ABLL_0649	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ABLL_0652	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ABLL_0658	COG0714	Associated with various cellular activities
ABLL_0659	COG0052	Belongs to the universal ribosomal protein uS2 family
ABLL_0660	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ABLL_0661	COG1136	(ABC) transporter
ABLL_0663	COG0194	GDP metabolic process
ABLL_0664	COG5002	protein histidine kinase activity
ABLL_0664	COG5001	Diguanylate cyclase
ABLL_0665	COG2217	Heavy metal translocating P-type atpase
ABLL_0668	COG4608	Belongs to the ABC transporter superfamily
ABLL_0669	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ABLL_0672	COG1355	regulation of microtubule-based process
ABLL_0674	COG1121	(ABC) transporter
ABLL_0675	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ABLL_0678	COG2996	Protein conserved in bacteria
ABLL_0679	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ABLL_0680	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
ABLL_0682	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ABLL_0684	COG0210	DNA helicase
ABLL_0685	COG0569	domain protein
ABLL_0685	COG0475	glutathione-regulated potassium exporter activity
ABLL_0686	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ABLL_0691	COG3258	Cytochrome c
ABLL_0699	COG0693	protein deglycase activity
ABLL_0703	COG0525	valine-tRNA ligase activity
ABLL_0704	COG0534	Mate efflux family protein
ABLL_0706	COG4895	conserved protein (DUF2196)
ABLL_0707	COG1047	Peptidyl-prolyl cis-trans
ABLL_0711	COG2814	Major facilitator Superfamily
ABLL_0712	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ABLL_0714	COG2197	response regulator
ABLL_0720	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ABLL_0721	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ABLL_0722	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ABLL_0727	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ABLL_0729	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
ABLL_0730	COG1309	transcriptional regulator
ABLL_0731	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ABLL_0735	COG0840	transmembrane signaling receptor activity
ABLL_0736	COG2199	diguanylate cyclase activity
ABLL_0736	COG2200	EAL domain
ABLL_0738	COG0439	Biotin carboxylase
ABLL_0739	COG3040	lipid binding
ABLL_0744	COG2151	metal-sulfur cluster biosynthetic enzyme
ABLL_0745	COG2166	iron-sulfur cluster assembly
ABLL_0746	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ABLL_0748	COG0396	ATPase activity
ABLL_0749	COG0719	Fe-S assembly protein
ABLL_0751	COG1366	Belongs to the anti-sigma-factor antagonist family
ABLL_0751	COG2202	Pas domain
ABLL_0753	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
ABLL_0753	COG2906	2 iron, 2 sulfur cluster binding
ABLL_0753	COG0822	iron-sulfur transferase activity
ABLL_0757	COG2239	Acts as a magnesium transporter
ABLL_0759	COG3706	GGDEF domain
ABLL_0763	COG0165	Argininosuccinate lyase
ABLL_0765	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ABLL_0766	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ABLL_0769	COG0556	nucleotide-excision repair
ABLL_0770	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ABLL_0772	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ABLL_0777	COG0698	ribose 5-phosphate isomerase
ABLL_0778	COG0681	Belongs to the peptidase S26 family
ABLL_0779	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ABLL_0780	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ABLL_0781	COG0193	aminoacyl-tRNA hydrolase activity
ABLL_0784	COG0860	N-Acetylmuramoyl-L-alanine amidase
ABLL_0786	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ABLL_0788	COG1758	RNA polymerase activity
ABLL_0789	COG0528	UMP kinase activity
ABLL_0791	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ABLL_0792	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ABLL_0793	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ABLL_0795	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ABLL_0796	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ABLL_0798	COG4191	Histidine kinase
ABLL_0799	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ABLL_0801	COG0305	Participates in initiation and elongation during chromosome replication
ABLL_0804	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ABLL_0806	COG1086	Polysaccharide biosynthesis protein
ABLL_0807	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ABLL_0809	COG2089	acid synthase
ABLL_0810	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ABLL_0811	COG0107	imidazoleglycerol-phosphate synthase activity
ABLL_0822	COG1215	transferase activity, transferring glycosyl groups
ABLL_0823	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ABLL_0824	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
ABLL_0825	COG1086	Polysaccharide biosynthesis protein
ABLL_0827	COG1793	dna ligase
ABLL_0828	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ABLL_0829	COG0133	tryptophan synthase activity
ABLL_0831	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ABLL_0832	COG0848	biopolymer transport protein
ABLL_0837	COG1136	(ABC) transporter
ABLL_0837	COG0577	efflux transmembrane transporter activity
ABLL_0838	COG0577	efflux transmembrane transporter activity
ABLL_0838	COG1136	(ABC) transporter
ABLL_0849	COG0114	fumarate hydratase activity
ABLL_0851	COG3852	Histidine kinase
ABLL_0852	COG0745	RESPONSE REGULATOR receiver
ABLL_0857	COG4773	Receptor
ABLL_0863	COG1918	ferrous iron import across plasma membrane
ABLL_0863	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
ABLL_0864	COG1918	ferrous iron import across plasma membrane
ABLL_0865	COG4771	TonB-dependent receptor
ABLL_0866	COG2819	hydrolase of the alpha beta superfamily
ABLL_0867	COG3920	Histidine kinase
ABLL_0868	COG0784	Response regulator, receiver
ABLL_0869	COG4771	TonB-dependent receptor
ABLL_0872	COG2801	Transposase and inactivated derivatives
ABLL_0876	COG2801	Transposase and inactivated derivatives
ABLL_0877	COG0745	RESPONSE REGULATOR receiver
ABLL_0884	COG0514	ATP-dependent DNA helicase (RecQ)
ABLL_0894	COG0419	ATPase involved in DNA repair
ABLL_0895	COG0420	3'-5' exonuclease activity
ABLL_0898	COG0039	L-malate dehydrogenase activity
ABLL_0899	COG3422	double-strand break repair
ABLL_0922	COG0012	GTP binding
ABLL_0926	COG3123	guanosine phosphorylase activity
ABLL_0929	COG4974	Belongs to the 'phage' integrase family
ABLL_0934	COG2815	serine threonine protein kinase
ABLL_0934	COG0515	serine threonine protein kinase
ABLL_0935	COG2815	serine threonine protein kinase
ABLL_0935	COG0515	serine threonine protein kinase
ABLL_0938	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ABLL_0941	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ABLL_0959	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ABLL_0960	COG0585	pseudouridine synthase activity
ABLL_0962	COG4773	Receptor
ABLL_0963	COG0840	transmembrane signaling receptor activity
ABLL_0964	COG0632	four-way junction helicase activity
ABLL_0965	COG1181	Belongs to the D-alanine--D-alanine ligase family
ABLL_0967	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ABLL_0969	COG1733	regulation of RNA biosynthetic process
ABLL_0970	COG0778	Nitroreductase
ABLL_0972	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ABLL_0973	COG0051	transcription antitermination factor activity, RNA binding
ABLL_0974	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ABLL_0975	COG0088	Forms part of the polypeptide exit tunnel
ABLL_0976	COG0089	rRNA binding
ABLL_0977	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ABLL_0978	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ABLL_0979	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ABLL_0980	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ABLL_0981	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ABLL_0982	COG0255	Belongs to the universal ribosomal protein uL29 family
ABLL_0983	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ABLL_0984	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ABLL_0985	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ABLL_0986	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ABLL_0987	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ABLL_0988	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ABLL_0989	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ABLL_0990	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ABLL_0991	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ABLL_0992	COG0200	Binds to the 23S rRNA
ABLL_0993	COG0201	protein transport
ABLL_0994	COG0024	Methionine aminopeptidase
ABLL_0995	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ABLL_0997	COG1573	uracil-dna glycosylase
ABLL_0999	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ABLL_1002	COG1032	radical SAM domain protein
ABLL_1004	COG0563	adenylate kinase activity
ABLL_1007	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ABLL_1008	COG0322	excinuclease ABC activity
ABLL_1010	COG3706	GGDEF domain
ABLL_1012	COG3201	nicotinamide mononucleotide transporter
ABLL_1013	COG0386	Belongs to the glutathione peroxidase family
ABLL_1014	COG0840	transmembrane signaling receptor activity
ABLL_1015	COG0840	transmembrane signaling receptor activity
ABLL_1016	COG0840	transmembrane signaling receptor activity
ABLL_1017	COG0840	transmembrane signaling receptor activity
ABLL_1020	COG0745	RESPONSE REGULATOR receiver
ABLL_1020	COG3706	GGDEF domain
ABLL_1027	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ABLL_1029	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ABLL_1030	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
ABLL_1032	COG0559	Belongs to the binding-protein-dependent transport system permease family
ABLL_1036	COG0829	nickel cation binding
ABLL_1037	COG0683	leucine binding
ABLL_1039	COG4177	L-phenylalanine transmembrane transporter activity
ABLL_1040	COG0411	ABC transporter
ABLL_1045	COG4266	Belongs to the allantoicase family
ABLL_1048	COG0832	Belongs to the urease beta subunit family
ABLL_1048	COG0831	urea catabolic process
ABLL_1049	COG0804	urea catabolic process
ABLL_1050	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
ABLL_1052	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
ABLL_1058	COG1846	Transcriptional regulator
ABLL_1060	COG3706	GGDEF domain
ABLL_1061	COG0708	Exodeoxyribonuclease III
ABLL_1068	COG0166	Belongs to the GPI family
ABLL_1071	COG2252	PERMEase
ABLL_1072	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
ABLL_1074	COG2363	Small membrane protein
ABLL_1076	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ABLL_1077	COG2233	PERMEase
ABLL_1078	COG1666	GTP binding
ABLL_1080	COG0745	RESPONSE REGULATOR receiver
ABLL_1084	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
ABLL_1085	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ABLL_1086	COG0135	phosphoribosylanthranilate isomerase activity
ABLL_1087	COG2176	DNA-directed DNA polymerase activity
ABLL_1088	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ABLL_1090	COG1013	pyruvate-flavodoxin oxidoreductase activity
ABLL_1091	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ABLL_1091	COG0674	pyruvate-flavodoxin oxidoreductase activity
ABLL_1093	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
ABLL_1094	COG0727	PFAM Uncharacterised protein family (UPF0153)
ABLL_1096	COG0134	indole-3-glycerol-phosphate synthase activity
ABLL_1097	COG0583	DNA-binding transcription factor activity
ABLL_1099	COG0840	transmembrane signaling receptor activity
ABLL_1101	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ABLL_1102	COG0750	zinc metalloprotease
ABLL_1103	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ABLL_1104	COG1028	Short-chain dehydrogenase reductase Sdr
ABLL_1105	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ABLL_1108	COG0167	dihydroorotate dehydrogenase activity
ABLL_1109	COG1132	(ABC) transporter
ABLL_1110	COG0728	peptidoglycan biosynthetic process
ABLL_1112	COG1592	Rubrerythrin
ABLL_1114	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ABLL_1115	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ABLL_1123	COG1858	cytochrome C peroxidase
ABLL_1126	COG0552	protein localization to endoplasmic reticulum
ABLL_1127	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ABLL_1129	COG1418	mRNA catabolic process
ABLL_1130	COG0742	ribosomal rna small subunit methyltransferase
ABLL_1131	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ABLL_1133	COG0300	oxidoreductase activity
ABLL_1136	COG3258	Cytochrome c
ABLL_1139	COG5002	protein histidine kinase activity
ABLL_1142	COG1610	YqeY-like protein
ABLL_1144	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ABLL_1145	COG0436	Aminotransferase
ABLL_1146	COG1451	nucleotide metabolic process
ABLL_1148	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ABLL_1149	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ABLL_1150	COG0519	Catalyzes the synthesis of GMP from XMP
ABLL_1150	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ABLL_1158	COG2226	methyltransferase
ABLL_1164	COG0596	Alpha beta hydrolase
ABLL_1165	COG0204	Acyl-transferase
ABLL_1167	COG0531	amino acid
ABLL_1171	COG1696	Membrane protein involved in D-alanine export
ABLL_1172	COG0564	pseudouridine synthase activity
ABLL_1175	COG1393	Belongs to the ArsC family
ABLL_1176	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ABLL_1177	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ABLL_1179	COG2186	Transcriptional regulator
ABLL_1180	COG2807	transmembrane transport
ABLL_1183	COG1028	Short-chain dehydrogenase reductase Sdr
ABLL_1184	COG0519	Catalyzes the synthesis of GMP from XMP
ABLL_1184	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ABLL_1191	COG1253	flavin adenine dinucleotide binding
ABLL_1192	COG2989	Protein conserved in bacteria
ABLL_1194	COG0628	permease
ABLL_1197	COG1253	flavin adenine dinucleotide binding
ABLL_1200	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ABLL_1208	COG1181	Belongs to the D-alanine--D-alanine ligase family
ABLL_1209	COG0513	Belongs to the DEAD box helicase family
ABLL_1210	COG2200	EAL domain
ABLL_1210	COG3287	FIST C domain
ABLL_1210	COG2199	diguanylate cyclase activity
ABLL_1211	COG0840	transmembrane signaling receptor activity
ABLL_1212	COG0840	transmembrane signaling receptor activity
ABLL_1216	COG1045	serine acetyltransferase
ABLL_1217	COG1166	arginine decarboxylase activity
ABLL_1218	COG0124	histidyl-tRNA synthetase
ABLL_1219	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ABLL_1220	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ABLL_1221	COG0163	prenyltransferase activity
ABLL_1223	COG0359	binds to the 23S rRNA
ABLL_1224	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
ABLL_1225	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
ABLL_1227	COG0084	hydrolase, TatD family'
ABLL_1229	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ABLL_1230	COG0131	Imidazoleglycerol-phosphate dehydratase
ABLL_1231	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ABLL_1234	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ABLL_1237	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ABLL_1239	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ABLL_1240	COG3576	pyridoxamine 5-phosphate
ABLL_1244	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ABLL_1246	COG2897	thiosulfate sulfurtransferase activity
ABLL_1248	COG1338	Plays a role in the flagellum-specific transport system
ABLL_1260	COG0849	cell division
ABLL_1261	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ABLL_1262	COG2391	methyltransferase activity
ABLL_1267	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ABLL_1269	COG1722	exodeoxyribonuclease VII activity
ABLL_1271	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ABLL_1272	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ABLL_1298	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ABLL_1338	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ABLL_1339	COG1360	Flagellar Motor Protein
ABLL_1340	COG0861	Integral membrane protein TerC family
ABLL_1344	COG0842	Transport permease protein
ABLL_1345	COG0842	Transport permease protein
ABLL_1346	COG1131	(ABC) transporter
ABLL_1347	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ABLL_1348	COG0789	Transcriptional regulator
ABLL_1349	COG0484	heat shock protein binding
ABLL_1352	COG2201	protein-glutamate methylesterase activity
ABLL_1354	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ABLL_1354	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
ABLL_1377	COG0582	viral genome integration into host DNA
ABLL_1378	COG0776	regulation of translation
ABLL_1380	COG0275	rRNA processing
ABLL_1386	COG0318	PFAM AMP-dependent synthetase and ligase
ABLL_1388	COG4865	methylaspartate mutase activity
ABLL_1390	COG0039	L-malate dehydrogenase activity
ABLL_1394	COG4591	ABC-type transport system involved in lipoprotein release permease component
ABLL_1395	COG0653	protein targeting
ABLL_1397	COG2207	Transcriptional regulator
ABLL_1398	COG1979	alcohol dehydrogenase
ABLL_1400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ABLL_1400	COG4191	Histidine kinase
ABLL_1401	COG1587	Uroporphyrinogen-III synthase
ABLL_1401	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ABLL_1403	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ABLL_1404	COG0243	molybdopterin cofactor binding
ABLL_1405	COG2200	EAL domain
ABLL_1405	COG3287	FIST C domain
ABLL_1405	COG2199	diguanylate cyclase activity
ABLL_1406	COG0515	serine threonine protein kinase
ABLL_1406	COG2815	serine threonine protein kinase
ABLL_1407	COG2223	nitrite transmembrane transporter activity
ABLL_1408	COG0754	glutathionylspermidine amidase activity
ABLL_1410	COG3706	GGDEF domain
ABLL_1414	COG0745	RESPONSE REGULATOR receiver
ABLL_1416	COG0745	RESPONSE REGULATOR receiver
ABLL_1419	COG0024	Methionine aminopeptidase
ABLL_1427	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ABLL_1430	COG0281	malic enzyme
ABLL_1430	COG0280	phosphate acetyltransferase
ABLL_1431	COG0788	formyltetrahydrofolate deformylase activity
ABLL_1432	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ABLL_1434	COG0745	RESPONSE REGULATOR receiver
ABLL_1436	COG0330	HflC and HflK could
ABLL_1440	COG1271	oxidase subunit
ABLL_1445	COG0450	alkyl hydroperoxide reductase
ABLL_1448	COG0811	peptide transport
ABLL_1449	COG0848	biopolymer transport protein
ABLL_1452	COG0419	ATPase involved in DNA repair
ABLL_1457	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ABLL_1458	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
ABLL_1459	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
ABLL_1460	COG1187	pseudouridine synthase activity
ABLL_1465	COG4206	TonB-dependent receptor
ABLL_1468	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ABLL_1469	COG0406	alpha-ribazole phosphatase activity
ABLL_1473	COG0667	Aldo Keto reductase
ABLL_1474	COG0840	transmembrane signaling receptor activity
ABLL_1477	COG0824	Thioesterase
ABLL_1479	COG0501	Belongs to the peptidase M48B family
ABLL_1480	COG1322	Protein conserved in bacteria
ABLL_1482	COG2321	neutral zinc metallopeptidase
ABLL_1487	COG0037	tRNA processing
ABLL_1488	COG1683	Conserved Protein
ABLL_1493	COG5001	Diguanylate cyclase
ABLL_1493	COG2203	Gaf domain
ABLL_1493	COG3706	GGDEF domain
ABLL_1493	COG4251	negative regulation of phosphorylation
ABLL_1497	COG0028	Belongs to the TPP enzyme family
ABLL_1498	COG0440	acetolactate synthase activity
ABLL_1499	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ABLL_1500	COG1196	nuclear chromosome segregation
ABLL_1500	COG1674	ftsk spoiiie
ABLL_1501	COG0745	RESPONSE REGULATOR receiver
ABLL_1502	COG2205	protein histidine kinase activity
ABLL_1504	COG1749	Flagellar hook protein flgE
ABLL_1511	COG1160	GTP binding
ABLL_1512	COG0659	secondary active sulfate transmembrane transporter activity
ABLL_1514	COG0151	Belongs to the GarS family
ABLL_1516	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ABLL_1518	COG1185	polyribonucleotide nucleotidyltransferase activity
ABLL_1519	COG0745	RESPONSE REGULATOR receiver
ABLL_1520	COG0643	Histidine kinase
ABLL_1520	COG2198	Histidine kinase
ABLL_1521	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ABLL_1522	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
ABLL_1523	COG2201	protein-glutamate methylesterase activity
ABLL_1525	COG0582	viral genome integration into host DNA
ABLL_1529	COG0339	signal peptide processing
ABLL_1530	COG2890	protein-(glutamine-N5) methyltransferase activity
ABLL_1531	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ABLL_1532	COG0494	nUDIX hydrolase
ABLL_1533	COG0527	aspartate kinase activity
ABLL_1536	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ABLL_1537	COG0287	Prephenate dehydrogenase
ABLL_1538	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ABLL_1539	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
ABLL_1540	COG0612	Peptidase, M16
ABLL_1541	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ABLL_1547	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
ABLL_1549	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ABLL_1549	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ABLL_1554	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
ABLL_1555	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
ABLL_1559	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ABLL_1565	COG0357	Ribosomal RNA small subunit methyltransferase G
ABLL_1566	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ABLL_1567	COG0113	porphobilinogen synthase activity
ABLL_1568	COG0840	transmembrane signaling receptor activity
ABLL_1572	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ABLL_1572	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ABLL_1573	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ABLL_1574	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ABLL_1576	COG1663	tetraacyldisaccharide 4'-kinase activity
ABLL_1578	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ABLL_1582	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ABLL_1583	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ABLL_1584	COG0805	protein transport
ABLL_1585	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ABLL_1592	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ABLL_1595	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ABLL_1599	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ABLL_1599	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ABLL_1600	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
ABLL_1601	COG2199	diguanylate cyclase activity
ABLL_1601	COG3287	FIST C domain
ABLL_1601	COG2200	EAL domain
ABLL_1602	COG3706	GGDEF domain
ABLL_1603	COG1137	ATPase activity
ABLL_1604	COG0802	atpase or kinase
ABLL_1605	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ABLL_1607	COG0137	argininosuccinate synthase activity
ABLL_1609	COG0189	ligase activity
ABLL_1612	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ABLL_1613	COG0569	domain protein
ABLL_1614	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ABLL_1615	COG0745	RESPONSE REGULATOR receiver
ABLL_1616	COG2205	protein histidine kinase activity
ABLL_1618	COG0784	Response regulator, receiver
ABLL_1618	COG4191	Histidine kinase
ABLL_1620	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ABLL_1622	COG0484	heat shock protein binding
ABLL_1623	COG0133	tryptophan synthase activity
ABLL_1627	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ABLL_1628	COG5001	Diguanylate cyclase
ABLL_1629	COG5001	Diguanylate cyclase
ABLL_1629	COG2203	Gaf domain
ABLL_1629	COG4251	negative regulation of phosphorylation
ABLL_1629	COG3706	GGDEF domain
ABLL_1630	COG0500	methyltransferase
ABLL_1631	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ABLL_1631	COG1333	cytochrome c biogenesis protein
ABLL_1632	COG0745	RESPONSE REGULATOR receiver
ABLL_1634	COG2195	Cleaves the N-terminal amino acid of tripeptides
ABLL_1637	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ABLL_1638	COG2205	protein histidine kinase activity
ABLL_1638	COG4999	Histidine kinase
ABLL_1638	COG3850	Histidine kinase
ABLL_1638	COG3437	response regulator, receiver
ABLL_1639	COG2205	protein histidine kinase activity
ABLL_1640	COG3437	response regulator, receiver
ABLL_1640	COG0784	Response regulator, receiver
ABLL_1641	COG1607	acyl-coa hydrolase
ABLL_1642	COG0488	(ABC) transporter
ABLL_1644	COG1979	alcohol dehydrogenase
ABLL_1645	COG2207	Transcriptional regulator
ABLL_1646	COG3706	GGDEF domain
ABLL_1647	COG2197	response regulator
ABLL_1648	COG0643	Histidine kinase
ABLL_1648	COG2198	Histidine kinase
ABLL_1649	COG2205	protein histidine kinase activity
ABLL_1652	COG3710	Transcriptional regulator
ABLL_1653	COG0778	Nitroreductase
ABLL_1657	COG2249	NAD(P)H dehydrogenase (quinone) activity
ABLL_1658	COG1733	regulation of RNA biosynthetic process
ABLL_1661	COG2855	membrane
ABLL_1662	COG0583	DNA-binding transcription factor activity
ABLL_1663	COG3706	GGDEF domain
ABLL_1664	COG1881	PFAM PEBP family protein
ABLL_1666	COG3706	GGDEF domain
ABLL_1669	COG2076	Multidrug Resistance protein
ABLL_1670	COG2249	NAD(P)H dehydrogenase (quinone) activity
ABLL_1673	COG4191	Histidine kinase
ABLL_1673	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ABLL_1677	COG2824	Alkylphosphonate utilization operon protein PhnA
ABLL_1679	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ABLL_1680	COG0095	Lipoate-protein ligase
ABLL_1681	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ABLL_1682	COG0508	dehydrogenase complex catalyzes the overall conversion of
ABLL_1683	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ABLL_1686	COG3706	GGDEF domain
ABLL_1686	COG0745	RESPONSE REGULATOR receiver
ABLL_1694	COG2329	Antibiotic biosynthesis monooxygenase
ABLL_1697	COG1605	Chorismate mutase
ABLL_1697	COG0077	Prephenate dehydratase
ABLL_1699	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ABLL_1700	COG1119	ATPase activity
ABLL_1701	COG0784	Response regulator, receiver
ABLL_1701	COG2205	protein histidine kinase activity
ABLL_1702	COG2205	protein histidine kinase activity
ABLL_1702	COG2202	Pas domain
ABLL_1703	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ABLL_1707	COG1193	negative regulation of DNA recombination
ABLL_1709	COG0471	metal ion transport
ABLL_1710	COG0521	Mo-molybdopterin cofactor biosynthetic process
ABLL_1713	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ABLL_1715	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ABLL_1721	COG2274	protein secretion by the type I secretion system
ABLL_1724	COG0745	RESPONSE REGULATOR receiver
ABLL_1727	COG0513	Belongs to the DEAD box helicase family
ABLL_1729	COG3706	GGDEF domain
ABLL_1730	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ABLL_1732	COG3279	Response regulator of the LytR AlgR family
ABLL_1743	COG5002	protein histidine kinase activity
ABLL_1744	COG0745	RESPONSE REGULATOR receiver
ABLL_1748	COG1132	(ABC) transporter
ABLL_1749	COG0628	permease
ABLL_1750	COG1472	Belongs to the glycosyl hydrolase 3 family
ABLL_1755	COG1620	l-lactate permease
ABLL_1764	COG2204	response regulator
ABLL_1768	COG0517	IMP dehydrogenase activity
ABLL_1768	COG0516	GMP reductase activity
ABLL_1769	COG0154	amidase activity
ABLL_1770	COG0203	ribosomal protein L17
ABLL_1771	COG0202	RNA polymerase activity
ABLL_1772	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ABLL_1773	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ABLL_1774	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ABLL_1775	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ABLL_1778	COG0473	3-isopropylmalate dehydrogenase activity
ABLL_1779	COG0066	3-isopropylmalate dehydratase activity
ABLL_1780	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ABLL_1784	COG3123	guanosine phosphorylase activity
ABLL_1785	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ABLL_1788	COG0772	Belongs to the SEDS family
ABLL_1789	COG0564	pseudouridine synthase activity
ABLL_1790	COG0366	Alpha amylase catalytic
ABLL_1790	COG3103	Sh3 type 3 domain protein
ABLL_1791	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ABLL_1792	COG2884	Cell division ATP-binding protein ftsE
ABLL_1795	COG1671	Belongs to the UPF0178 family
ABLL_1797	COG0488	(ABC) transporter
ABLL_1798	COG2171	N-acyltransferase activity
ABLL_1799	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ABLL_1804	COG3706	GGDEF domain
ABLL_1806	COG0309	Hydrogenase expression formation protein (HypE)
ABLL_1809	COG0409	Hydrogenase expression formation protein
ABLL_1810	COG0298	carbon dioxide binding
ABLL_1811	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
ABLL_1814	COG0840	transmembrane signaling receptor activity
ABLL_1816	COG2081	HI0933 family
ABLL_1817	COG2076	Multidrug Resistance protein
ABLL_1820	COG0439	Biotin carboxylase
ABLL_1826	COG2354	Protein conserved in bacteria
ABLL_1828	COG2814	Major facilitator Superfamily
ABLL_1832	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ABLL_1832	COG0301	tRNA thio-modification
ABLL_1837	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
ABLL_1842	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
ABLL_1865	COG2369	cell adhesion
ABLL_1893	COG1518	maintenance of DNA repeat elements
ABLL_1908	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
ABLL_1909	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
ABLL_1911	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
ABLL_1914	COG1049	propionate catabolic process, 2-methylcitrate cycle
ABLL_1917	COG0242	peptide deformylase activity
ABLL_1920	COG1022	Amp-dependent synthetase and ligase
ABLL_1921	COG0183	Belongs to the thiolase family
ABLL_1922	COG1024	Enoyl-CoA hydratase
ABLL_1922	COG1250	3-hydroxyacyl-CoA dehydrogenase
ABLL_1923	COG1960	acyl-CoA dehydrogenase activity
ABLL_1929	COG0217	transcriptional regulatory protein
ABLL_1930	COG2853	Lipoprotein
ABLL_1933	COG1611	Belongs to the LOG family
ABLL_1934	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ABLL_1935	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ABLL_1939	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
ABLL_1942	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ABLL_1944	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ABLL_1945	COG0477	Major facilitator Superfamily
ABLL_1949	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ABLL_1949	COG0475	glutathione-regulated potassium exporter activity
ABLL_1951	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ABLL_1952	COG2169	Transcriptional regulator
ABLL_1952	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ABLL_1958	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ABLL_1959	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ABLL_1960	COG2258	MOSC domain
ABLL_1964	COG0513	Belongs to the DEAD box helicase family
ABLL_1970	COG1944	ATP diphosphatase activity
ABLL_1974	COG0840	transmembrane signaling receptor activity
ABLL_1975	COG0328	RNA-DNA hybrid ribonuclease activity
ABLL_1976	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ABLL_1981	COG0446	pyridine nucleotide-disulphide oxidoreductase
ABLL_1987	COG0745	RESPONSE REGULATOR receiver
ABLL_1988	COG3437	response regulator, receiver
ABLL_1994	COG4191	Histidine kinase
ABLL_1996	COG5001	Diguanylate cyclase
ABLL_1996	COG5002	protein histidine kinase activity
ABLL_1998	COG1078	dGTPase activity
ABLL_1999	COG0259	pyridoxamine-phosphate oxidase activity
ABLL_2001	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ABLL_2003	COG0513	Belongs to the DEAD box helicase family
ABLL_2006	COG2199	diguanylate cyclase activity
ABLL_2006	COG3287	FIST C domain
ABLL_2006	COG2200	EAL domain
ABLL_2008	COG1984	allophanate hydrolase subunit 2
ABLL_2010	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
ABLL_2013	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ABLL_2014	COG2207	Transcriptional regulator
ABLL_2014	COG4753	response regulator
ABLL_2015	COG0840	transmembrane signaling receptor activity
ABLL_2019	COG0842	Transport permease protein
ABLL_2020	COG1129	ABC transporter
ABLL_2020	COG0842	Transport permease protein
ABLL_2021	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ABLL_2023	COG0306	phosphate transporter
ABLL_2026	COG0326	Molecular chaperone. Has ATPase activity
ABLL_2027	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ABLL_2034	COG2995	paraquat-inducible protein a
ABLL_2037	COG5001	Diguanylate cyclase
ABLL_2037	COG5002	protein histidine kinase activity
ABLL_2041	COG2902	Dehydrogenase
ABLL_2043	COG4335	DNA alkylation repair
ABLL_2046	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ABLL_2050	COG0010	Belongs to the arginase family
ABLL_2051	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ABLL_2053	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ABLL_2054	COG1227	inorganic diphosphatase activity
ABLL_2057	COG1027	Aspartate ammonia-lyase
ABLL_2058	COG0745	RESPONSE REGULATOR receiver
ABLL_2060	COG1115	amino acid carrier protein
ABLL_2061	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ABLL_2062	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ABLL_2063	COG1047	Peptidyl-prolyl cis-trans
ABLL_2065	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
ABLL_2065	COG2885	chlorophyll binding
ABLL_2066	COG2193	ferroxidase activity
ABLL_2067	COG0823	Involved in the tonB-independent uptake of proteins
ABLL_2069	COG0848	biopolymer transport protein
ABLL_2070	COG0811	peptide transport
ABLL_2071	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ABLL_2072	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ABLL_2073	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ABLL_2074	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ABLL_2075	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ABLL_2076	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ABLL_2078	COG1475	DNA binding
ABLL_2079	COG1192	Involved in chromosome partitioning
ABLL_2080	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
ABLL_2080	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
ABLL_2082	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ABLL_2083	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ABLL_2084	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ABLL_2085	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ABLL_2086	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ABLL_2088	COG0358	DNA primase activity
ABLL_2090	COG0571	ribonuclease III activity
ABLL_2091	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ABLL_2093	COG0501	Belongs to the peptidase M48B family
ABLL_2097	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ABLL_2099	COG0706	membrane insertase activity
ABLL_2100	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ABLL_2102	COG0230	Belongs to the bacterial ribosomal protein bL34 family
ABLL_2103	COG0542	response to heat
ABLL_2106	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ABLL_2109	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ABLL_2113	COG1120	ATPase activity
ABLL_2122	COG0811	peptide transport
ABLL_2123	COG0848	biopolymer transport protein
ABLL_2126	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ABLL_2127	COG3437	response regulator, receiver
ABLL_2128	COG3437	response regulator, receiver
ABLL_2129	COG2205	protein histidine kinase activity
ABLL_2129	COG0784	Response regulator, receiver
ABLL_2130	COG0179	Fumarylacetoacetate (FAA) hydrolase
ABLL_2135	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ABLL_2135	COG4191	Histidine kinase
ABLL_2136	COG0138	bifunctional purine biosynthesis protein purh
ABLL_2137	COG0004	ammonium transporteR
ABLL_2138	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ABLL_2140	COG1196	nuclear chromosome segregation
ABLL_2140	COG0741	lytic transglycosylase activity
ABLL_2140	COG0739	heme binding
ABLL_2143	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ABLL_2144	COG0662	Cupin 2, conserved barrel domain protein
ABLL_2146	COG0302	gtp cyclohydrolase
ABLL_2147	COG0598	Magnesium transport protein CorA
ABLL_2148	COG1459	type II secretion system
ABLL_2152	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ABLL_2153	COG0606	chelatase, subunit chli
ABLL_2155	COG0242	peptide deformylase activity
ABLL_2156	COG0740	serine-type endopeptidase activity
ABLL_2157	COG0544	peptidyl-prolyl cis-trans isomerase activity
ABLL_2162	COG1773	rubredoxin
ABLL_2164	COG0582	viral genome integration into host DNA
ABLL_2177	COG3501	Rhs element vgr protein
ABLL_2192	COG0739	heme binding
ABLL_2195	COG3501	Rhs element vgr protein
ABLL_2196	COG3179	chitinase
ABLL_2199	COG3842	ATPase activity
ABLL_2200	COG1176	ABC-type spermidine putrescine transport system, permease component I
ABLL_2201	COG1177	transmembrane transport
ABLL_2202	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ABLL_2206	COG0626	cystathionine gamma-synthase activity
ABLL_2208	COG0745	RESPONSE REGULATOR receiver
ABLL_2209	COG0840	transmembrane signaling receptor activity
ABLL_2211	COG5002	protein histidine kinase activity
ABLL_2212	COG0840	transmembrane signaling receptor activity
ABLL_2213	COG0840	transmembrane signaling receptor activity
ABLL_2215	COG0583	DNA-binding transcription factor activity
ABLL_2220	COG0745	RESPONSE REGULATOR receiver
ABLL_2221	COG0456	acetyltransferase
ABLL_2222	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
ABLL_2225	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ABLL_2226	COG1028	Short-chain dehydrogenase reductase Sdr
ABLL_2227	COG2207	Transcriptional regulator
ABLL_2228	COG0720	synthase
ABLL_2231	COG1301	dicarboxylic acid transport
ABLL_2235	COG0840	transmembrane signaling receptor activity
ABLL_2236	COG1028	Short-chain dehydrogenase reductase Sdr
ABLL_2238	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ABLL_2238	COG4191	Histidine kinase
ABLL_2240	COG1858	cytochrome C peroxidase
ABLL_2246	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ABLL_2247	COG0668	transmembrane transport
ABLL_2252	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ABLL_2255	COG0348	domain, Protein
ABLL_2256	COG4191	Histidine kinase
ABLL_2257	COG2207	Transcriptional regulator
ABLL_2257	COG4753	response regulator
ABLL_2259	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ABLL_2260	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ABLL_2265	COG0716	FMN binding
ABLL_2268	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
ABLL_2270	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
ABLL_2271	COG0159	tryptophan synthase activity
ABLL_2272	COG0038	chloride channel
ABLL_2273	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ABLL_2274	COG2255	four-way junction helicase activity
ABLL_2275	COG0628	permease
ABLL_2277	COG4628	conserved protein (DUF2132)
ABLL_2278	COG0731	radical SAM domain protein
ABLL_2279	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ABLL_2281	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ABLL_2284	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ABLL_2286	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ABLL_2289	COG0438	transferase activity, transferring glycosyl groups
ABLL_2292	COG0438	transferase activity, transferring glycosyl groups
ABLL_2293	COG0726	polysaccharide deacetylase
ABLL_2294	COG0438	transferase activity, transferring glycosyl groups
ABLL_2295	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ABLL_2299	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ABLL_2301	COG0493	'glutamate synthase
ABLL_2302	COG0067	glutamate synthase
ABLL_2302	COG0069	glutamate synthase activity
ABLL_2302	COG0070	glutamate synthase
ABLL_2304	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ABLL_2305	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ABLL_2308	COG0745	RESPONSE REGULATOR receiver
ABLL_2315	COG0284	orotidine-5'-phosphate decarboxylase activity
ABLL_2316	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ABLL_2317	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ABLL_2318	COG3706	GGDEF domain
ABLL_2319	COG2877	3-deoxy-8-phosphooctulonate synthase activity
ABLL_2324	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ABLL_2329	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ABLL_2341	COG1739	Uncharacterized protein family UPF0029
ABLL_2343	COG0196	riboflavin kinase activity
ABLL_2344	COG2226	methyltransferase
ABLL_2345	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ABLL_2347	COG0277	FAD linked oxidase domain protein
ABLL_2349	COG5001	Diguanylate cyclase
ABLL_2349	COG3706	GGDEF domain
ABLL_2349	COG4251	negative regulation of phosphorylation
ABLL_2349	COG2203	Gaf domain
ABLL_2352	COG0542	response to heat
ABLL_2353	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
ABLL_2354	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ABLL_2357	COG2030	dehydratase
ABLL_2362	COG1970	mechanosensitive ion channel activity
ABLL_2363	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ABLL_2368	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ABLL_2369	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ABLL_2370	COG1157	protein secretion by the type III secretion system
ABLL_2372	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ABLL_2376	COG1677	Flagellar hook-basal body complex protein FliE
ABLL_2378	COG0455	bacterial-type flagellum organization
ABLL_2379	COG1419	protein localization to endoplasmic reticulum
ABLL_2385	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ABLL_2389	COG1749	Flagellar hook protein flgE
ABLL_2390	COG1749	Flagellar hook protein flgE
ABLL_2392	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ABLL_2394	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ABLL_2395	COG1766	The M ring may be actively involved in energy transduction
ABLL_2396	COG1815	bacterial-type flagellum-dependent cell motility
ABLL_2397	COG4786	Flagellar basal body rod
ABLL_2403	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ABLL_2405	COG0228	four-way junction DNA binding
ABLL_2406	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ABLL_2407	COG0564	pseudouridine synthase activity
ABLL_2408	COG1519	Transferase
ABLL_2410	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ABLL_2411	COG0752	glycyl-tRNA synthetase alpha subunit
ABLL_2413	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ABLL_2416	COG0840	transmembrane signaling receptor activity
ABLL_2416	COG0840	transmembrane signaling receptor activity
ABLL_2417	COG0497	DNA recombination
ABLL_2418	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ABLL_2419	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ABLL_2420	COG0049	tRNA binding
ABLL_2421	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ABLL_2422	COG2814	Major facilitator Superfamily
ABLL_2424	COG0840	transmembrane signaling receptor activity
ABLL_2429	COG0310	cobalt ion transport
ABLL_2436	COG1605	Chorismate mutase
ABLL_2436	COG0077	Prephenate dehydratase
ABLL_2443	COG4569	acetaldehyde dehydrogenase (acetylating) activity
ABLL_2448	COG0543	2 iron, 2 sulfur cluster binding
ABLL_2448	COG0633	Ferredoxin
ABLL_2449	COG0039	L-malate dehydrogenase activity
ABLL_2451	COG0784	Response regulator, receiver
ABLL_2454	COG0730	response to heat
ABLL_2463	COG0840	transmembrane signaling receptor activity
ABLL_2464	COG1028	Short-chain dehydrogenase reductase Sdr
ABLL_2465	COG0473	3-isopropylmalate dehydrogenase activity
ABLL_2468	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ABLL_2469	COG0085	RNA polymerase activity
ABLL_2470	COG0222	ribosome binding
ABLL_2471	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ABLL_2472	COG0081	regulation of translation
ABLL_2473	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ABLL_2474	COG0250	Participates in transcription elongation, termination and antitermination
ABLL_2476	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ABLL_2477	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ABLL_2478	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ABLL_2479	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ABLL_2480	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ABLL_2481	COG0444	Belongs to the ABC transporter superfamily
ABLL_2482	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
ABLL_2483	COG0174	glutamine synthetase
ABLL_2485	COG0745	RESPONSE REGULATOR receiver
ABLL_2485	COG3706	GGDEF domain
ABLL_2486	COG0314	molybdopterin synthase activity
ABLL_2488	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
ABLL_2489	COG1968	undecaprenyl-diphosphatase activity
ABLL_2491	COG0772	Belongs to the SEDS family
ABLL_2493	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ABLL_2496	COG0512	Glutamine amidotransferase of anthranilate synthase
ABLL_2497	COG1840	ABC-type Fe3 transport system, periplasmic component
ABLL_2498	COG1178	ABC-type Fe3 transport system permease component
ABLL_2499	COG3842	ATPase activity
ABLL_2507	COG2183	response to ionizing radiation
ABLL_2509	COG0251	oxidation-reduction process
ABLL_2512	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ABLL_2516	COG0335	large ribosomal subunit rRNA binding
ABLL_2517	COG0336	Belongs to the RNA methyltransferase TrmD family
ABLL_2519	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ABLL_2520	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ABLL_2521	COG0356	it plays a direct role in the translocation of protons across the membrane
ABLL_2523	COG1074	ATP-dependent DNA helicase activity
ABLL_2524	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ABLL_2525	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ABLL_2526	COG0723	plastoquinol--plastocyanin reductase activity
ABLL_2527	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ABLL_2530	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ABLL_2532	COG0303	'Molybdopterin
ABLL_2533	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ABLL_2535	COG0602	queuosine metabolic process
ABLL_2536	COG1028	Short-chain dehydrogenase reductase Sdr
ABLL_2537	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ABLL_2538	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ABLL_2539	COG0825	malonyl-CoA metabolic process
ABLL_2540	COG0537	adenosine 5'-monophosphoramidase activity
ABLL_2541	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ABLL_2542	COG0072	phenylalanine-tRNA ligase activity
ABLL_2542	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ABLL_2543	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ABLL_2544	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ABLL_2545	COG1185	polyribonucleotide nucleotidyltransferase activity
ABLL_2545	COG0539	negative regulation of cytoplasmic translation
ABLL_2546	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ABLL_2547	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ABLL_2548	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ABLL_2548	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ABLL_2549	COG0779	Required for maturation of 30S ribosomal subunits
ABLL_2550	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ABLL_2551	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ABLL_2553	COG0083	homoserine kinase activity
ABLL_2555	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
ABLL_2558	COG0157	Belongs to the NadC ModD family
ABLL_2560	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ABLL_2562	COG4773	Receptor
ABLL_2564	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ABLL_2568	COG1538	Outer membrane efflux protein
ABLL_2569	COG1846	Transcriptional regulator
ABLL_2577	COG3278	Belongs to the heme-copper respiratory oxidase family
ABLL_2578	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ABLL_2579	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ABLL_2580	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ABLL_2581	COG0210	DNA helicase
ABLL_2583	COG1242	4 iron, 4 sulfur cluster binding
ABLL_2584	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ABLL_2585	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ABLL_2586	COG0492	ferredoxin-NADP+ reductase activity
ABLL_2587	COG3118	belongs to the thioredoxin family
ABLL_2588	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ABLL_2594	COG0791	NLP P60 protein
ABLL_2595	COG0791	NLP P60 protein
ABLL_2598	COG0697	spore germination
ABLL_2600	COG0424	maF-like protein
ABLL_2602	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ABLL_2603	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ABLL_2604	COG1605	Chorismate mutase
ABLL_2604	COG0077	Prephenate dehydratase
ABLL_2605	COG0019	diaminopimelate decarboxylase activity
ABLL_2606	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ABLL_2607	COG0149	triose-phosphate isomerase activity
ABLL_2608	COG0126	phosphoglycerate kinase activity
ABLL_2610	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ABLL_2612	COG0018	arginyl-trna synthetase
ABLL_2614	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ABLL_2615	COG0204	Acyl-transferase
ABLL_2617	COG0047	phosphoribosylformylglycinamidine synthase activity
ABLL_2618	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ABLL_2620	COG0793	Belongs to the peptidase S41A family
ABLL_2623	COG0585	pseudouridine synthase activity
ABLL_2624	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ABLL_2629	COG4191	Histidine kinase
ABLL_2632	COG2205	protein histidine kinase activity
ABLL_2632	COG0784	Response regulator, receiver
ABLL_2633	COG0129	dihydroxy-acid dehydratase activity
ABLL_2634	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ABLL_2635	COG0745	RESPONSE REGULATOR receiver
ABLL_2639	COG0702	epimerase
ABLL_2642	COG1492	cobalamin metabolic process
ABLL_2643	COG2205	protein histidine kinase activity
ABLL_2647	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ABLL_2648	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
ABLL_2650	COG2095	MarC family integral membrane protein
ABLL_2652	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
ABLL_2653	COG0471	metal ion transport
ABLL_2655	COG4232	protein-disulfide reductase activity
ABLL_2656	COG3118	belongs to the thioredoxin family
ABLL_2658	COG0189	ligase activity
ABLL_2661	COG2199	diguanylate cyclase activity
ABLL_2661	COG3287	FIST C domain
ABLL_2661	COG2200	EAL domain
ABLL_2664	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
ABLL_2665	COG0443	Heat shock 70 kDa protein
ABLL_2666	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ABLL_2667	COG1420	regulation of RNA biosynthetic process
ABLL_2670	COG2197	response regulator
ABLL_2672	COG0101	tRNA pseudouridine synthase activity
ABLL_2674	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ABLL_2675	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ABLL_2676	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ABLL_2677	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ABLL_2679	COG4581	dead DEAH box helicase
ABLL_2680	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ABLL_2684	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ABLL_2685	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ABLL_2687	COG2089	acid synthase
ABLL_2688	COG0662	Cupin 2, conserved barrel domain protein
ABLL_2688	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
ABLL_2690	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ABLL_2691	COG0148	phosphopyruvate hydratase activity
ABLL_2694	COG0475	glutathione-regulated potassium exporter activity
ABLL_2694	COG0569	domain protein
ABLL_2695	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ABLL_2699	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
ABLL_2701	COG1007	ATP synthesis coupled electron transport
ABLL_2703	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ABLL_2704	COG0713	ATP synthesis coupled electron transport
ABLL_2705	COG0839	Belongs to the complex I subunit 6 family
ABLL_2706	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ABLL_2707	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ABLL_2708	COG1034	ATP synthesis coupled electron transport
ABLL_2711	COG0649	NAD binding
ABLL_2713	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ABLL_2714	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ABLL_2715	COG1222	aaa ATPase
ABLL_2721	COG0659	secondary active sulfate transmembrane transporter activity
ABLL_2723	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
ABLL_2724	COG1252	NADH dehydrogenase
ABLL_2725	COG0733	neurotransmitter:sodium symporter activity
ABLL_2727	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ABLL_2729	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ABLL_2730	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ABLL_2731	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ABLL_2735	COG0445	tRNA wobble uridine modification
ABLL_2738	COG0348	domain, Protein
ABLL_2739	COG0504	CTP synthase activity
ABLL_2740	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ABLL_2740	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
ABLL_2743	COG0693	protein deglycase activity
ABLL_2746	COG0587	DNA-directed DNA polymerase activity
ABLL_2747	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
ABLL_2750	COG0315	cyclic pyranopterin monophosphate synthase activity
ABLL_2751	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ABLL_2752	COG0670	Belongs to the BI1 family
ABLL_2753	COG0352	thiamine-phosphate diphosphorylase activity
ABLL_2755	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ABLL_2757	COG0233	cytoplasmic translational termination
ABLL_2758	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ABLL_2760	COG2814	Major facilitator Superfamily
ABLL_2761	COG3264	Mechanosensitive ion channel
ABLL_2761	COG1196	nuclear chromosome segregation
ABLL_2763	COG3022	response to hydroperoxide
ABLL_2764	COG3012	SEC-C Motif Domain Protein
ABLL_2770	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ABLL_2773	COG1704	LemA family
ABLL_2776	COG0546	phosphoglycolate phosphatase activity
ABLL_2780	COG2814	Major facilitator Superfamily
ABLL_2783	COG0745	RESPONSE REGULATOR receiver
ABLL_2784	COG0840	transmembrane signaling receptor activity
ABLL_2785	COG0784	Response regulator, receiver
ABLL_2785	COG3437	response regulator, receiver
ABLL_2788	COG0745	RESPONSE REGULATOR receiver
ABLL_2788	COG3706	GGDEF domain
ABLL_2790	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ABLL_2791	COG1538	Outer membrane efflux protein
ABLL_2796	COG2081	HI0933 family
ABLL_2802	COG1959	2 iron, 2 sulfur cluster binding
ABLL_2805	COG0175	sulfate reduction
ABLL_2806	COG0175	sulfate reduction
ABLL_2807	COG2895	sulfate adenylyltransferase (ATP) activity
ABLL_2809	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ABLL_2810	COG1408	metallophosphoesterase
ABLL_2811	COG0071	Belongs to the small heat shock protein (HSP20) family
ABLL_2815	COG0840	transmembrane signaling receptor activity
ABLL_2817	COG4208	sulfate ABC transporter
ABLL_2818	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
ABLL_2819	COG3287	FIST C domain
ABLL_2819	COG2200	EAL domain
ABLL_2819	COG2199	diguanylate cyclase activity
ABLL_2820	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
ABLL_2821	COG1959	2 iron, 2 sulfur cluster binding
ABLL_2825	COG2308	Evidence 4 Homologs of previously reported genes of
ABLL_2829	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ABLL_2830	COG1858	cytochrome C peroxidase
ABLL_2835	COG0745	RESPONSE REGULATOR receiver
ABLL_2836	COG2770	Histidine kinase
ABLL_2836	COG2205	protein histidine kinase activity
ABLL_2837	COG2226	methyltransferase
ABLL_2839	COG0784	Response regulator, receiver
ABLL_2839	COG3437	response regulator, receiver
ABLL_2840	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
ABLL_2841	COG2066	Belongs to the glutaminase family
ABLL_2842	COG2860	membrane
ABLL_2844	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ABLL_2845	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group