locus-tag	class	description
LPB137_00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
LPB137_00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
LPB137_00015	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
LPB137_00025	ENOG4105CAY	ferredoxin--nadp reductase
LPB137_00030	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
LPB137_00040	ENOG410631K	Membrane
LPB137_00050	ENOG4105EI2	Pseudouridine synthase
LPB137_00055	ENOG4107QTF	adenylosuccinate lyase
LPB137_00060	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
LPB137_00065	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
LPB137_00130	ENOG4107VQW	regulatoR
LPB137_00135	ENOG4105BZU	Histidine kinase
LPB137_00140	ENOG4105C58	cytochrome c oxidase accessory protein ccog
LPB137_00145	ENOG4105BZU	Histidine kinase
LPB137_00155	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
LPB137_00160	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
LPB137_00165	ENOG4105BZU	Histidine kinase
LPB137_00175	ENOG4105BZU	Histidine kinase
LPB137_00180	ENOG41066A3	ATP guanido phosphotransferase
LPB137_00190	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
LPB137_00200	ENOG4105KVH	Transcriptional regulator
LPB137_00205	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
LPB137_00210	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
LPB137_00220	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
LPB137_00225	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
LPB137_00235	ENOG4105CH5	extracellular solute-binding protein, family 7
LPB137_00240	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
LPB137_00245	ENOG4105BZU	Histidine kinase
LPB137_00250	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
LPB137_00255	ENOG4107QR9	Iron-sulfur cluster binding protein
LPB137_00260	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
LPB137_00275	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
LPB137_00280	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
LPB137_00285	ENOG4105C1J	atp-dependent rna helicase
LPB137_00290	ENOG4105CJ3	phosphate transporter
LPB137_00300	ENOG4105CAQ	asparagine synthetase
LPB137_00310	ENOG4105E7Q	Cob(II)yrinic acid a,c-diamide reductase
LPB137_00315	ENOG4105CH5	extracellular solute-binding protein, family 7
LPB137_00325	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
LPB137_00335	ENOG4108IAB	Phoh family
LPB137_00340	ENOG4108YXA	Membrane
LPB137_00345	ENOG4105D1H	recombination factor protein RarA
LPB137_00350	ENOG4105FE9	pseudouridine synthase
LPB137_00355	ENOG4105C2X	Arabinose 5-phosphate isomerase
LPB137_00365	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
LPB137_00370	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
LPB137_00385	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
LPB137_00390	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
LPB137_00400	ENOG41062D9	Histidine kinase
LPB137_00420	ENOG4108IJF	Heavy metal efflux pump, CzcA
LPB137_00430	ENOG4105E18	UPF0276 protein
LPB137_00440	ENOG4108ISG	Major Facilitator
LPB137_00445	ENOG4105UQX	Mate efflux family protein
LPB137_00450	ENOG4105D6E	homoserine dehydrogenase
LPB137_00455	ENOG4105CHM	Aminotransferase
LPB137_00465	ENOG4105C2N	RNA methyltransferase TrmH family group 3
LPB137_00475	ENOG41082DI	50s ribosomal protein l31
LPB137_00480	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
LPB137_00510	ENOG4105F9F	transposase
LPB137_00575	ENOG41067QW	Transcriptional regulator
LPB137_00590	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
LPB137_00610	ENOG4105CFI	type iii restriction protein res subunit
LPB137_00615	ENOG4105C0W	non-ribosomal peptide synthetase
LPB137_00670	ENOG4107QHF	type ii secretion system protein e
LPB137_00700	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
LPB137_00710	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
LPB137_00715	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
LPB137_00720	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
LPB137_00725	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
LPB137_00735	ENOG410829K	Lysine exporter protein (Lyse ygga)
LPB137_00740	ENOG4108IG5	Transcriptional regulator
LPB137_00745	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
LPB137_00760	ENOG4108YYC	ycei family
LPB137_00765	ENOG4107UUH	Aminotransferase
LPB137_00770	ENOG4105CYE	ATP phosphoribosyltransferase regulatory subunit
LPB137_00775	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
LPB137_00785	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
LPB137_00800	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
LPB137_00820	ENOG4105D1F	ATP-binding protein
LPB137_00825	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
LPB137_00840	ENOG4105CM2	brancheD-chain amino acid aminotransferase
LPB137_00850	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
LPB137_00870	ENOG4107Y9U	Membrane
LPB137_00905	ENOG4105D3R	alkyl hydroperoxide reductase
LPB137_00925	ENOG4108I6A	alcohol dehydrogenase
LPB137_00930	ENOG4105CF7	AraC family transcriptional regulator
LPB137_00960	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
LPB137_00970	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
LPB137_00975	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
LPB137_00995	ENOG4108W2Y	isochorismatase
LPB137_01000	ENOG4108KK1	membrane protein AbrB duplication
LPB137_01005	ENOG41080BE	Methyl-accepting chemotaxis sensory transducer
LPB137_01005	ENOG41080BE	Methyl-accepting chemotaxis sensory transducer
LPB137_01010	ENOG4105DDK	oxidoreductase, beta subunit
LPB137_01015	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
LPB137_01025	ENOG4105EJ5	oxidoreductase gamma subunit
LPB137_01030	ENOG4107XGZ	Hydrolase
LPB137_01040	ENOG4108UJD	30S ribosomal protein S9
LPB137_01045	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
LPB137_01050	ENOG4105BZU	Histidine kinase
LPB137_01070	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
LPB137_01075	ENOG4105E2Z	phosphate ABC transporter (Permease
LPB137_01080	ENOG4105C8U	phosphate abc transporter
LPB137_01095	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
LPB137_01100	ENOG4108317	Binds directly to 16S ribosomal RNA (By similarity)
LPB137_01105	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
LPB137_01110	ENOG410813J	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
LPB137_01115	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
LPB137_01125	ENOG4107SA8	fad-dependent pyridine nucleotide-disulfide oxidoreductase
LPB137_01140	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
LPB137_01145	ENOG41084M8	50s ribosomal protein L35
LPB137_01150	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
LPB137_01155	ENOG4105C22	threonyL-tRNA synthetase
LPB137_01180	ENOG4105KNE	Phosphatidate cytidylyltransferase
LPB137_01185	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
LPB137_01205	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
LPB137_01210	ENOG4108ZJT	translation initiation factor, Sui1
LPB137_01225	ENOG4108ENG	carbohydrate kinase, YjeF related protein
LPB137_01265	ENOG4108VAU	general secretion pathway protein G
LPB137_01305	ENOG4105GVR	general secretion pathway protein D
LPB137_01310	ENOG4107QHF	type ii secretion system protein e
LPB137_01355	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
LPB137_01360	ENOG4105BZU	Histidine kinase
LPB137_01395	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
LPB137_01410	ENOG4108QDE	fad dependent oxidoreductase
LPB137_01430	ENOG4105C8Q	Methyl-accepting chemotaxis
LPB137_01440	ENOG4105QNF	Outer membrane lipoprotein
LPB137_01445	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
LPB137_01450	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
LPB137_01460	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
LPB137_01475	ENOG4105BZU	Histidine kinase
LPB137_01480	ENOG4105DY9	regulatoR
LPB137_01485	ENOG4108HRK	Histidine kinase
LPB137_01490	ENOG4105EWK	phytoene
LPB137_01495	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
LPB137_01510	ENOG4105BZU	Histidine kinase
LPB137_01515	ENOG4105BZU	Histidine kinase
LPB137_01530	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
LPB137_01545	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
LPB137_01560	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LPB137_01575	ENOG4105CN1	protease
LPB137_01580	ENOG4105C8V	SAICAR synthetase
LPB137_01585	ENOG4105VR9	phosphoribosylformylglycinamidine synthase
LPB137_01590	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
LPB137_01600	ENOG4105E9Q	Acyl-transferase
LPB137_01605	ENOG4105WMR	Protein CrcB homolog
LPB137_01610	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
LPB137_01615	ENOG4105C75	arginyL-tRNA synthetase
LPB137_01625	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
LPB137_01630	ENOG4105BZA	Phosphoglycerate kinase
LPB137_01635	ENOG4105CP7	Triose-phosphate isomerase
LPB137_01640	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
LPB137_01645	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
LPB137_01650	ENOG4105CQC	Prephenate dehydratase
LPB137_01655	ENOG4105CIH	Imidazole acetol-phosphate transaminase
LPB137_01660	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
LPB137_01675	ENOG4105C8Q	Methyl-accepting chemotaxis
LPB137_01680	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
LPB137_01690	ENOG4107YJQ	MAF-like protein
LPB137_01705	ENOG4108PCN	EamA-like transporter family
LPB137_01715	ENOG4107TT5	NLP P60 protein
LPB137_01720	ENOG4107TT5	NLP P60 protein
LPB137_01740	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
LPB137_01750	ENOG4107QPK	)-transporter
LPB137_01755	ENOG4105BZU	Histidine kinase
LPB137_01760	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
LPB137_01765	ENOG4105C3M	thioredoxin reductase
LPB137_01770	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
LPB137_01775	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
LPB137_01780	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
LPB137_01790	ENOG4105C4R	Atp-dependent dna helicase
LPB137_01795	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
LPB137_01800	ENOG4107Z7S	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
LPB137_01805	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
LPB137_01810	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
LPB137_01850	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
LPB137_01870	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
LPB137_01880	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
LPB137_01895	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
LPB137_01905	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
LPB137_01915	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
LPB137_01920	ENOG4105MGB	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
LPB137_01925	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
LPB137_01935	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
LPB137_01940	ENOG4108JQ1	Dehydrogenase
LPB137_01945	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
LPB137_01950	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
LPB137_01955	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
LPB137_01960	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
LPB137_01965	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
LPB137_01975	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
LPB137_01980	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
LPB137_01985	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
LPB137_01990	ENOG4105CHR	reductase
LPB137_01995	ENOG4107SPB	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
LPB137_02005	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
LPB137_02010	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
LPB137_02030	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
LPB137_02035	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
LPB137_02040	ENOG4107QID	Threonine synthase
LPB137_02045	ENOG4105CAS	nag kinase
LPB137_02050	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
LPB137_02055	ENOG4107WJT	it plays a direct role in the translocation of protons across the membrane (By similarity)
LPB137_02060	ENOG4105C7B	Threonine dehydratase
LPB137_02065	ENOG4107QYE	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
LPB137_02075	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
LPB137_02080	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
LPB137_02100	ENOG4105DKW	ABC transporter
LPB137_02110	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
LPB137_02120	ENOG4105CIF	Ornithine Cyclodeaminase
LPB137_02125	ENOG4105CTU	Proline racemase
LPB137_02140	ENOG4105GBT	ABC transporter
LPB137_02145	ENOG4105E5Q	amino acid AbC transporter
LPB137_02150	ENOG4105CDA	abc transporter atp-binding protein
LPB137_02165	ENOG4105CTU	Proline racemase
LPB137_02190	ENOG4105C32	Amino acid ABC transporter (Permease)
LPB137_02195	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
LPB137_02200	ENOG4105C0Z	ABC transporter
LPB137_02205	ENOG4108IV0	ABC, transporter
LPB137_02210	ENOG4105C26	Dehydrogenase
LPB137_02240	ENOG41066UZ	arginase EC 3.5.3.1
LPB137_02245	ENOG4105DWD	nucleoside recognition domain protein
LPB137_02250	ENOG4107XM3	UPF0442 protein
LPB137_02255	ENOG4105DWK	Membrane
LPB137_02270	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
LPB137_02290	ENOG4105KCK	Peptidoglycan-associated lipoprotein
LPB137_02305	ENOG4107XTP	(EAL) domain protein
LPB137_02315	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
LPB137_02320	ENOG41061ZR	Transcriptional regulator
LPB137_02325	ENOG4105C31	Tryptophanyl-tRNA synthetase
LPB137_02340	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
LPB137_02345	ENOG4108HGU	Histidine kinase
LPB137_02350	ENOG4108IYU	L-aspartate oxidase
LPB137_02370	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
LPB137_02390	ENOG4108ZMS	Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity)
LPB137_02395	ENOG4105GXZ	Ferredoxin-type protein NapH
LPB137_02400	ENOG4108BGM	Quinol dehydrogenase periplasmic component
LPB137_02405	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
LPB137_02410	ENOG4108MTB	glycosyl transferase family
LPB137_02420	ENOG4105C8Q	Methyl-accepting chemotaxis
LPB137_02430	ENOG4105CDA	abc transporter atp-binding protein
LPB137_02435	ENOG4105DRP	amino acid AbC transporter
LPB137_02440	ENOG4105EZ7	amino acid ABC transporter
LPB137_02445	ENOG4107QXX	ABC transporter
LPB137_02470	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
LPB137_02480	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
LPB137_02510	ENOG4105DSQ	Nitric oxide reductase
LPB137_02515	ENOG4108VKQ	nitriC oxide reductase
LPB137_02540	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
LPB137_02550	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
LPB137_02560	ENOG4108KA0	Inherit from COG: Phosphoesterase, DHHA1
LPB137_02570	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
LPB137_02580	ENOG4105CJW	magnesium transporter
LPB137_02590	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
LPB137_02610	ENOG4105EGS	Mechanosensitive ion channel
LPB137_02615	ENOG4105K4P	CoA-binding domain protein
LPB137_02620	ENOG4105DHQ	Histidine kinase
LPB137_02625	ENOG4105ETX	regulatoR
LPB137_02630	ENOG4105EIN	peptidylprolyl cis-trans isomerase
LPB137_02635	ENOG4105D2N	Aldolase
LPB137_02645	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
LPB137_02665	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
LPB137_02670	ENOG4108SNK	aliphatic sulfonates import ATP-binding protein SsuB
LPB137_02690	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
LPB137_02710	ENOG4105JIE	May be involved in the transport of PQQ or its precursor to the periplasm (By similarity)
LPB137_02720	ENOG4105WF7	pyrroloquinoline quinone biosynthesis protein d
LPB137_02725	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
LPB137_02745	ENOG4105BZU	Histidine kinase
LPB137_02750	ENOG4105C26	Dehydrogenase
LPB137_02760	ENOG4105M8F	Biopolymer transport protein exbD tolR
LPB137_02780	ENOG4105BZU	Histidine kinase
LPB137_02790	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
LPB137_02800	ENOG4105EAH	synthase
LPB137_02805	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
LPB137_02810	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
LPB137_02820	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
LPB137_02830	ENOG4105CK1	PTS System
LPB137_02835	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
LPB137_02840	ENOG4105VIE	preprotein translocase, subunit YajC
LPB137_02845	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
LPB137_02850	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
LPB137_02865	ENOG4105C8T	Leucyl-tRNA synthetase
LPB137_02875	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
LPB137_02880	ENOG4105DR5	peptidase
LPB137_02950	ENOG4108JA2	transcriptioN-repair coupling factor
LPB137_02960	ENOG4105CBX	hi0933 family
LPB137_02980	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
LPB137_02990	ENOG4105CBX	hi0933 family
LPB137_02995	ENOG4105D48	metallophosphoesterase
LPB137_03015	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
LPB137_03020	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
LPB137_03025	ENOG4108V3W	Chemotaxis protein, CheW
LPB137_03035	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
LPB137_03040	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
LPB137_03050	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
LPB137_03055	ENOG41084FT	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
LPB137_03065	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
LPB137_03070	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
LPB137_03075	ENOG4105BZU	Histidine kinase
LPB137_03095	ENOG4105ECY	inositol monophosphatase
LPB137_03100	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
LPB137_03105	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
LPB137_03110	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
LPB137_03115	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
LPB137_03120	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LPB137_03130	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
LPB137_03135	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
LPB137_03140	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
LPB137_03150	ENOG4105BZU	Histidine kinase
LPB137_03160	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
LPB137_03180	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
LPB137_03185	ENOG4105BZU	Histidine kinase
LPB137_03200	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
LPB137_03205	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
LPB137_03215	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
LPB137_03220	ENOG4105CDV	Ompa motb domain protein
LPB137_03225	ENOG4105CDV	Ompa motb domain protein
LPB137_03230	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
LPB137_03240	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
LPB137_03245	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
LPB137_03250	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LPB137_03255	ENOG4105DC7	peptidase M24
LPB137_03260	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
LPB137_03265	ENOG4107SYB	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
LPB137_03270	ENOG4105D07	Signal peptide peptidase, SppA
LPB137_03280	ENOG4108IJ2	phosphate acetyltransferase
LPB137_03285	ENOG41083X2	DNA polymerase III, epsilon subunit
LPB137_03315	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
LPB137_03325	ENOG4107QN1	sodium solute
LPB137_03335	ENOG4108STX	response regulator
LPB137_03340	ENOG4105US7	Histidine kinase
LPB137_03430	ENOG4105CEV	competence damage-inducible protein
LPB137_03435	ENOG4107RSR	Malate quinone oxidoreductase
LPB137_03440	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
LPB137_03455	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
LPB137_03480	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
LPB137_03490	ENOG4105CE9	30S ribosomal protein S2
LPB137_03495	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
LPB137_03510	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
LPB137_03520	ENOG4105C59	p-type ATPase
LPB137_03535	ENOG4108JQ7	(ABC) transporter
LPB137_03540	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
LPB137_03550	ENOG41074MP	UPF0103 Mediator of ErbB2-driven cell motility-containing protein
LPB137_03555	ENOG4107S90	membrAne
LPB137_03560	ENOG4105FDK	ABC transporter
LPB137_03575	ENOG4105QNR	S1 RNA binding domain protein
LPB137_03580	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
LPB137_03590	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
LPB137_03595	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
LPB137_03600	ENOG4105ENA	helicase
LPB137_03605	ENOG4105BZU	Histidine kinase
LPB137_03610	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
LPB137_03620	ENOG4105BZS	acriflavin resistance protein
LPB137_03645	ENOG4105DKW	ABC transporter
LPB137_03660	ENOG4107RDB	Major Facilitator
LPB137_03665	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
LPB137_03690	ENOG410901F	(LipO)protein
LPB137_03695	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
LPB137_03715	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
LPB137_03740	ENOG4105D64	Mechanosensitive ion channel
LPB137_03745	ENOG4105BZU	Histidine kinase
LPB137_03765	ENOG41084IH	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
LPB137_03810	ENOG4105BZU	Histidine kinase
LPB137_03815	ENOG4105CHR	reductase
LPB137_03820	ENOG4105C8Q	Methyl-accepting chemotaxis
LPB137_03845	ENOG4106AXJ	AraC family transcriptional regulator
LPB137_03850	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
LPB137_03865	ENOG4105D7X	high-affinity nickel-transporter
LPB137_03875	ENOG4105C28	cystathionine
LPB137_03880	ENOG4105BZU	Histidine kinase
LPB137_03895	ENOG4107T0D	ABC, transporter
LPB137_03905	ENOG4105DP9	ABC transporter
LPB137_03920	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
LPB137_03925	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
LPB137_03930	ENOG4105DF9	Lipoate-protein, ligase
LPB137_03935	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
LPB137_03940	ENOG4107QSN	dihydrolipoamide acetyltransferase
LPB137_03945	ENOG4107QN2	dihydrolipoyl dehydrogenase
LPB137_03965	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
LPB137_03975	ENOG4105CNG	UPF0061 protein
LPB137_03995	ENOG4105W1N	transcriptional regulator
LPB137_04005	ENOG410624X	efflux transporter, rnd family, mfp subunit
LPB137_04040	ENOG4105VG1	fes assembly suf system protein
LPB137_04045	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
LPB137_04050	ENOG4105C9B	Cysteine desulfurase
LPB137_04060	ENOG4105C3K	feS assembly ATPase SufC
LPB137_04070	ENOG4105E5Q	amino acid AbC transporter
LPB137_04075	ENOG4105EAB	amino acid AbC transporter
LPB137_04085	ENOG4105C3J	Cysteine desulfurase
LPB137_04095	ENOG4105CJW	magnesium transporter
LPB137_04110	ENOG4105FQT	
LPB137_04115	ENOG4105CH7	arginosuccinase
LPB137_04125	ENOG4105CUZ	uba thif-type nad fad binding protein
LPB137_04130	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
LPB137_04135	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
LPB137_04150	ENOG4105CKW	Inner membrane protein yedI
LPB137_04155	ENOG4105BZU	Histidine kinase
LPB137_04160	ENOG4105CT1	(ABC) transporter
LPB137_04170	ENOG4105CSM	endonuclease III
LPB137_04195	ENOG4108YZG	isomerase
LPB137_04205	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
LPB137_04210	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
LPB137_04225	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
LPB137_04235	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
LPB137_04240	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
LPB137_04245	ENOG410692R	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
LPB137_04250	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
LPB137_04260	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
LPB137_04265	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
LPB137_04270	ENOG4105CRQ	synthase (Component I)
LPB137_04280	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
LPB137_04285	ENOG4105CRK	lysyL-tRNA synthetase
LPB137_04295	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
LPB137_04300	ENOG4105CDU	Replicative dna helicase
LPB137_04315	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
LPB137_04320	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
LPB137_04330	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
LPB137_04340	ENOG4105BZU	Histidine kinase
LPB137_04345	ENOG4108WZ2	response regulator
LPB137_04350	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
LPB137_04355	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
LPB137_04360	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
LPB137_04365	ENOG4105BZU	Histidine kinase
LPB137_04380	ENOG4105BZU	Histidine kinase
LPB137_04395	ENOG4107UCJ	Catalyzes the synthesis of activated sulfate (By similarity)
LPB137_04410	ENOG4105D3R	alkyl hydroperoxide reductase
LPB137_04415	ENOG4105BZU	Histidine kinase
LPB137_04415	ENOG4105BZU	Histidine kinase
LPB137_04425	ENOG4105C3G	gtp-binding protein
LPB137_04445	ENOG4105NBK	UPF0345 protein
LPB137_04460	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
LPB137_04465	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
LPB137_04475	ENOG4105C8Q	Methyl-accepting chemotaxis
LPB137_04480	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
LPB137_04485	ENOG4105CPF	Cell wall formation (By similarity)
LPB137_04495	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
LPB137_04510	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
LPB137_04515	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
LPB137_04520	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
LPB137_04525	ENOG4105KZZ	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
LPB137_04530	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LPB137_04535	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
LPB137_04540	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
LPB137_04545	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
LPB137_04550	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
LPB137_04555	ENOG41084HJ	50s ribosomal protein l29
LPB137_04560	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
LPB137_04565	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
LPB137_04570	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
LPB137_04580	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
LPB137_04585	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
LPB137_04590	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
LPB137_04595	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
LPB137_04600	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
LPB137_04605	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
LPB137_04610	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
LPB137_04615	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
LPB137_04620	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
LPB137_04630	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
LPB137_04640	ENOG4105C9M	aspartyl-trna synthetase
LPB137_04655	ENOG4105CCT	upf0313 protein
LPB137_04660	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
LPB137_04670	ENOG4105C8Q	Methyl-accepting chemotaxis
LPB137_04680	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
LPB137_04695	ENOG4108V06	Glutathione peroxidase
LPB137_04710	ENOG4105KVH	Transcriptional regulator
LPB137_04715	ENOG4108RCM	Nitroreductase
LPB137_04720	ENOG41079Y2	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone
LPB137_04730	ENOG4105GPY	SprT protein
LPB137_04735	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
LPB137_04740	ENOG4105DAA	L-lactate
LPB137_04750	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
LPB137_04775	ENOG4105DHQ	Histidine kinase
LPB137_04780	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
LPB137_04800	ENOG4105CA0	peroxidase
LPB137_04805	ENOG4105CGK	Exodeoxyribonuclease III
LPB137_04810	ENOG4105BZU	Histidine kinase
LPB137_04825	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LPB137_04855	ENOG4105BZU	Histidine kinase
LPB137_04860	ENOG4108IJ0	Aspartate ammonia-lyase
LPB137_04870	ENOG41090A1	ferritin
LPB137_04875	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
LPB137_04880	ENOG4105VYW	UPF0251 protein
LPB137_04890	ENOG4105C4M	(Ubiquinol oxidase) subunit I
LPB137_04895	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
LPB137_04905	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
LPB137_04915	ENOG4105CYW	agmatinase
LPB137_04920	ENOG4105F1N	DNA alkylation repair
LPB137_04925	ENOG4108Z66	YbaK ebsC protein
LPB137_04930	ENOG4105C7I	Dehydrogenase
LPB137_04940	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
LPB137_04975	ENOG4105BZU	Histidine kinase
LPB137_05000	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
LPB137_05015	ENOG4105C59	p-type ATPase
LPB137_05020	ENOG4105KTU	Transcriptional regulator, arsr family
LPB137_05035	ENOG4105E3B	Multicopper oxidase
LPB137_05050	ENOG41082YX	Transcriptional regulator, arsr family
LPB137_05075	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
LPB137_05080	ENOG4108XTP	Transcriptional regulator
LPB137_05140	ENOG4105RWS	endonuclease I
LPB137_05185	ENOG41088T4	Helicase IV
LPB137_05275	ENOG4105F1S	paraquat-inducible protein a
LPB137_05280	ENOG4105DY2	Paraquat-inducible protein b
LPB137_05290	ENOG4108IJ7	Glycine betaine
LPB137_05295	ENOG4108HQS	Glycine betaine
LPB137_05300	ENOG4105GIJ	Glycine betaine
LPB137_05305	ENOG4105GIJ	Glycine betaine
LPB137_05320	ENOG4105DQ4	alcohol dehydrogenase
LPB137_05335	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
LPB137_05375	ENOG4105CQZ	Histidine kinase
LPB137_05380	ENOG4107VQW	regulatoR
LPB137_05385	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
LPB137_05395	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
LPB137_05400	ENOG4105E7W	lamb ycsf family protein
LPB137_05405	ENOG4105P4J	Allophanate hydrolase, subunit 1
LPB137_05415	ENOG4105E7W	lamb ycsf family protein
LPB137_05425	ENOG4105BZU	Histidine kinase
LPB137_05440	ENOG4105BZU	Histidine kinase
LPB137_05445	ENOG4105C1J	atp-dependent rna helicase
LPB137_05455	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
LPB137_05475	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
LPB137_05480	ENOG4105DCI	Phosphohydrolase
LPB137_05485	ENOG4108IAB	Phoh family
LPB137_05540	ENOG4105EM7	Selenocysteine-specific translation elongation factor
LPB137_05545	ENOG4105C1Y	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis (By similarity)
LPB137_05550	ENOG4105BZU	Histidine kinase
LPB137_05555	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
LPB137_05560	ENOG4107T9Q	phosphonate abc transporter
LPB137_05565	ENOG4108VA1	ABC transporter
LPB137_05570	ENOG4105S7S	phosphonate abc transporter
LPB137_05580	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
LPB137_05620	ENOG4105QAX	Iron-sulfur
LPB137_05630	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
LPB137_05650	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
LPB137_05655	ENOG4105C8W	ABC transporter
LPB137_05660	ENOG4107A5B	Binding-protein-dependent transport systems, inner membrane component
LPB137_05715	ENOG4108IND	Tetr family transcriptional regulator
LPB137_05735	ENOG41082J7	Rhodanese domain protein
LPB137_05760	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
LPB137_05785	ENOG4105KME	endoribonuclease L-psp
LPB137_05790	ENOG4107QMZ	Dehydrogenase
LPB137_05795	ENOG4105BZG	amino acid carrier protein
LPB137_05800	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
LPB137_05825	ENOG4105DF3	Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds (By similarity)
LPB137_05840	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
LPB137_05885	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
LPB137_05910	ENOG4105CX6	glutaminyL-tRNA synthetase
LPB137_05915	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
LPB137_05930	ENOG4105CQZ	Histidine kinase
LPB137_05935	ENOG4105BZU	Histidine kinase
LPB137_05940	ENOG4105C5H	ABC transporter
LPB137_05945	ENOG4105BZU	Histidine kinase
LPB137_05950	ENOG4107T9Q	phosphonate abc transporter
LPB137_05955	ENOG4105BZU	Histidine kinase
LPB137_05965	ENOG4105BZU	Histidine kinase
LPB137_05970	ENOG4105D3R	alkyl hydroperoxide reductase
LPB137_05975	ENOG4105C3M	thioredoxin reductase
LPB137_05985	ENOG4105C8Q	Methyl-accepting chemotaxis
LPB137_06010	ENOG4105C1J	atp-dependent rna helicase
LPB137_06020	ENOG4105K3M	)-transporter
LPB137_06025	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
LPB137_06030	ENOG4105DWF	phosphomethylpyrimidine kinase
LPB137_06035	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
LPB137_06040	ENOG4107Z6I	Thiamine biosynthesis protein
LPB137_06045	ENOG4105ETU	transcriptional activator (TenA
LPB137_06050	ENOG4105Y36	Binding-protein-dependent transport systems, inner membrane component
LPB137_06055	ENOG4108YI8	ABC transporter
LPB137_06075	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
LPB137_06115	ENOG4105CHM	Aminotransferase
LPB137_06120	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
LPB137_06145	ENOG4105DR5	peptidase
LPB137_06150	ENOG4105CDY	transcriptional regulatory protein
LPB137_06170	ENOG4108TVT	permease
LPB137_06210	ENOG4107QIJ	Aconitate hydratase 2
LPB137_06225	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
LPB137_06235	ENOG4105CA0	peroxidase
LPB137_06250	ENOG4105VCH	membrane
LPB137_06260	ENOG4107R4J	Chloride channel
LPB137_06275	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
LPB137_06280	ENOG4107RY6	amino acid
LPB137_06295	ENOG4105C32	Amino acid ABC transporter (Permease)
LPB137_06300	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
LPB137_06305	ENOG4105C0Z	ABC transporter
LPB137_06310	ENOG4108IV0	ABC, transporter
LPB137_06350	ENOG4105C25	Primosomal protein n'
LPB137_06385	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
LPB137_06390	ENOG4105C7Z	Conserved Protein
LPB137_06400	ENOG4105C5H	ABC transporter
LPB137_06420	ENOG4108UPT	UPF0178 protein
LPB137_06440	ENOG4105CAK	Cell division ATP-binding protein ftsE
LPB137_06445	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
LPB137_06455	ENOG4105C34	Pseudouridine synthase
LPB137_06460	ENOG4105CNI	cell division protein FtsW
LPB137_06480	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
LPB137_06485	ENOG4105NBK	UPF0345 protein
LPB137_06505	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
LPB137_06510	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
LPB137_06515	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
LPB137_06530	ENOG41067V7	50S ribosomal protein L36
LPB137_06535	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LPB137_06540	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
LPB137_06545	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
LPB137_06550	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
LPB137_06555	ENOG4108ZT0	50S ribosomal protein l17
LPB137_06560	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
LPB137_06565	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
LPB137_06570	ENOG41082IR	Excinuclease ABC C subunit domain protein
LPB137_06600	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
LPB137_06605	ENOG4105K63	Thioredoxin
LPB137_06625	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
LPB137_06655	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
LPB137_06665	ENOG4105DWV	Homoserine O-trans-acetylase
LPB137_06675	ENOG4105D06	uba thif-type nad fad binding protein
LPB137_06680	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
LPB137_06695	ENOG4105D49	3-dehydroquinate synthase
LPB137_06705	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
LPB137_06710	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
LPB137_06720	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
LPB137_06725	ENOG4105C98	muts2 protein
LPB137_06750	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
LPB137_06770	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
LPB137_06790	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
LPB137_06795	ENOG4105BZU	Histidine kinase
LPB137_06800	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
LPB137_06810	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
LPB137_06825	ENOG4105KVH	Transcriptional regulator
LPB137_06830	ENOG4105NF4	modulator of drug activity
LPB137_06835	ENOG4108RCM	Nitroreductase
LPB137_06850	ENOG4105E0C	molybdate abc transporter
LPB137_06860	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
LPB137_06870	ENOG4105C5H	ABC transporter
LPB137_06880	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
LPB137_06885	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
LPB137_06910	ENOG4105CIN	aminoacyl-histidine dipeptidase
LPB137_06915	ENOG4105CRE	cytochrome C
LPB137_06920	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
LPB137_06925	ENOG4105BZU	Histidine kinase
LPB137_06930	ENOG4105BZU	Histidine kinase
LPB137_06935	ENOG4105C5X	domain protein
LPB137_06955	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
LPB137_06960	ENOG4105BZU	Histidine kinase
LPB137_06965	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
LPB137_06970	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
LPB137_06990	ENOG4108Z0R	Transferase
LPB137_06995	ENOG4105CDH	Citrulline--aspartate ligase
LPB137_07005	ENOG4107S1N	anthranilate phosphoribosyltransferase
LPB137_07010	ENOG4105K8N	protein family UPF0079, ATPase
LPB137_07015	ENOG4108IUZ	ABC transporter
LPB137_07020	ENOG4105BZU	Histidine kinase
LPB137_07025	ENOG4105BZU	Histidine kinase
LPB137_07030	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
LPB137_07035	ENOG4105C2M	dna polymerase I
LPB137_07055	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
LPB137_07060	ENOG4105DF6	Fe-S oxidoreductase
LPB137_07065	ENOG4105D4P	Coproporphyrinogen iii oxidase
LPB137_07070	ENOG4105DBV	ornithine carbamoyltransferase
LPB137_07075	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
LPB137_07090	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
LPB137_07095	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
LPB137_07100	ENOG4105D52	delta-aminolevulinic acid dehydratase
LPB137_07110	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
LPB137_07135	ENOG4105BZU	Histidine kinase
LPB137_07140	ENOG4107R50	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
LPB137_07160	ENOG4105CTD	carboxy-peptidase
LPB137_07175	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
LPB137_07185	ENOG4105DKT	Transcriptional regulator
LPB137_07190	ENOG4107UB3	HAD-superfamily hydrolase subfamily IA variant 3
LPB137_07215	ENOG4105DEI	Mannitol dehydrogenase
LPB137_07225	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
LPB137_07230	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
LPB137_07235	ENOG4105C01	Dihydroxy-acid dehydratase
LPB137_07240	ENOG4108UHU	Aldolase
LPB137_07245	ENOG4107QP8	phosphohexose isomerase
LPB137_07250	ENOG4105C26	Dehydrogenase
LPB137_07260	ENOG4105BZU	Histidine kinase
LPB137_07305	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
LPB137_07310	ENOG4105D9Q	decarboxylase (Beta subunit)
LPB137_07315	ENOG4107QSA	Oxaloacetate decarboxylase
LPB137_07335	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
LPB137_07345	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
LPB137_07370	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
LPB137_07380	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
LPB137_07385	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LPB137_07395	ENOG4105EEI	dihydropteroate synthase
LPB137_07410	ENOG4105CFH	Aspartokinase
LPB137_07415	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
LPB137_07420	ENOG4105CSA	Coproporphyrinogen iii oxidase
LPB137_07425	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
LPB137_07430	ENOG4105DGW	oligopeptidase A
LPB137_07445	ENOG4108EU4	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
LPB137_07450	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
LPB137_07455	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
LPB137_07460	ENOG4105BZU	Histidine kinase
LPB137_07465	ENOG4105CBS	Chea signal transduction histidine kinase
LPB137_07470	ENOG4108VYJ	response regulator receiver protein
LPB137_07475	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
LPB137_07495	ENOG4105C12	Phosphoribosylglycinamide synthetase
LPB137_07505	ENOG4105CHH	sulfate transporter
LPB137_07510	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
LPB137_07520	ENOG4105CNU	cell division protein FtsK
LPB137_07525	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
LPB137_07530	ENOG4108ZP8	Acetolactate synthase small subunit
LPB137_07535	ENOG4105C7K	acetolactate synthase
LPB137_07550	ENOG4108VTU	Cdp-alcohol phosphatidyltransferase
LPB137_07560	ENOG4105CHH	sulfate transporter
LPB137_07590	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
LPB137_07610	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
LPB137_07615	ENOG4105CGZ	zinc metallopeptidase
LPB137_07625	ENOG4105CGY	Dna recombination protein
LPB137_07630	ENOG4105C2Y	STE24 endopeptidase EC 3.4.24.84
LPB137_07635	ENOG4105BZU	Histidine kinase
LPB137_07640	ENOG4105N82	Endonuclease
LPB137_07645	ENOG4107YD3	Thioesterase
LPB137_07650	ENOG4105C8Q	Methyl-accepting chemotaxis
LPB137_07655	ENOG4105BZU	Histidine kinase
LPB137_07665	ENOG4105EB3	Histidine kinase
LPB137_07670	ENOG4108VB1	regulatoR
LPB137_07675	ENOG4108USZ	hydrogenase
LPB137_07685	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
LPB137_07690	ENOG4105F71	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
LPB137_07695	ENOG4105C45	hydrogenase expression formation protein (HypE)
LPB137_07700	ENOG4105CQS	hydrogenase expression formation protein HypD
LPB137_07705	ENOG4105WRB	Hydrogenase assembly chaperone hypC hupF
LPB137_07710	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
LPB137_07755	ENOG4105GR3	Histidine kinase
LPB137_07760	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
LPB137_07805	ENOG4105DPX	Hydrogenase, large subunit
LPB137_07810	ENOG4105E3S	small subunit
LPB137_07820	ENOG4105E3S	small subunit
LPB137_07835	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
LPB137_07840	ENOG4105C8Q	Methyl-accepting chemotaxis
LPB137_07860	ENOG4105D05	Receptor
LPB137_07875	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
LPB137_07895	ENOG4105CPC	Aldo Keto reductase
LPB137_07940	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
LPB137_07945	ENOG4108IU2	vtamin B12-transporter permease
LPB137_07950	ENOG4108JJB	ABC transporter
LPB137_07955	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
LPB137_07960	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
LPB137_07980	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
LPB137_07995	ENOG4105M15	transport protein ExbD
LPB137_08000	ENOG4105M8K	biopolymer transport protein
LPB137_08010	ENOG4107QX8	SPFH domain, Band 7 family protein
LPB137_08020	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
LPB137_08025	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
LPB137_08030	ENOG4105CIY	formyltetrahydrofolate deformylase
LPB137_08035	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
LPB137_08050	ENOG4105EB1	binding-protein-dependent transport systems inner membrane Component
LPB137_08065	ENOG4108IJ9	(ABC) transporter
LPB137_08070	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
LPB137_08075	ENOG4105FDP	GntR family transcriptional regulator
LPB137_08080	ENOG4105FDP	GntR family transcriptional regulator
LPB137_08085	ENOG4105C6K	Malic enzyme
LPB137_08090	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
LPB137_08095	ENOG4107RBS	Methyltransferase
LPB137_08100	ENOG4105E2X	shikimate dehydrogenase
LPB137_08125	ENOG4108UHV	Lipoprotein
LPB137_08130	ENOG4106032	Glutathionylspermidine synthase
LPB137_08140	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
LPB137_08145	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
LPB137_08150	ENOG4105C4K	Nad synthetase
LPB137_08170	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
LPB137_08175	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
LPB137_08190	ENOG4105C2C	drug resistance transporter, Bcr CflA
LPB137_08195	ENOG4105DN9	Na H antiporter
LPB137_08210	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
LPB137_08215	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
LPB137_08225	ENOG4105C8J	)-transporter
LPB137_08230	ENOG4105VEQ	Cold shock protein
LPB137_08245	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
LPB137_08255	ENOG4107GZ4	SanA protein
LPB137_08260	ENOG4105EBA	Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity)
LPB137_08275	ENOG4106MWK	domain protein
LPB137_08280	ENOG4105BZU	Histidine kinase
LPB137_08290	ENOG4105CHH	sulfate transporter
LPB137_08305	ENOG4107QUV	Domain protein
LPB137_08320	ENOG4105MRD	Phage derived protein Gp49-like (DUF891)
LPB137_08370	ENOG4107WZZ	SMC domain protein
LPB137_08415	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
LPB137_08425	ENOG4108UMZ	Cdp-alcohol phosphatidyltransferase
LPB137_08430	ENOG4108HPI	phosphatidate Cytidylyltransferase
LPB137_08435	ENOG4105E9Q	Acyl-transferase
LPB137_08440	ENOG4105E8V	Alpha Beta Hydrolase Fold protein
LPB137_08445	ENOG41077RS	Phosphatase
LPB137_08480	ENOG41064RH	membrane protein YliF
LPB137_08495	ENOG4105CGD	Nad-dependent epimerase dehydratase
LPB137_08515	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
LPB137_08525	ENOG410841J	DNA-binding protein Hu
LPB137_08530	ENOG4105CQ7	ATP-dependent helicase
LPB137_08540	ENOG4105C1J	atp-dependent rna helicase
LPB137_08575	ENOG4105ETX	regulatoR
LPB137_08600	ENOG4105BZ1	(ABC) transporter
LPB137_08605	ENOG4105C8Q	Methyl-accepting chemotaxis
LPB137_08610	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
LPB137_08625	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
LPB137_08630	ENOG4105D60	lipoprotein releasing system transmembrane protein
LPB137_08665	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
LPB137_08675	ENOG4105DVC	DnaJ domain protein
LPB137_08680	ENOG4105KNI	merR family transcriptional Regulator
LPB137_08685	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
LPB137_08690	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
LPB137_08700	ENOG4105C7H	Helicase, RecD TraA family
LPB137_08720	ENOG410821Z	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum (By similarity)
LPB137_08740	ENOG4105CJN	penicillin-binding protein
LPB137_08745	ENOG4105CN7	Flagellar biosynthetic protein FliP
LPB137_08765	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
LPB137_08775	ENOG4105BZU	Histidine kinase
LPB137_08780	ENOG4108YZY	peptidylprolyl cis-trans isomerase
LPB137_08800	ENOG4105BZS	acriflavin resistance protein
LPB137_08815	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
LPB137_08830	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
LPB137_08835	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
LPB137_08840	ENOG4105K6T	rare lipoprotein A
LPB137_08845	ENOG4105E9H	Lytic Murein transglycosylase
LPB137_08850	ENOG4105F8V	Hydrolase, tatD family
LPB137_08860	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
LPB137_08865	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
LPB137_08870	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
LPB137_08875	ENOG4105DHQ	Histidine kinase
LPB137_08890	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
LPB137_08895	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
LPB137_08900	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
LPB137_08905	ENOG4105CUT	histidyl-tRNA synthetase
LPB137_08910	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
LPB137_08915	ENOG4105D7W	serine acetyltransferase
LPB137_08925	ENOG4108I0Z	Aconitate hydratase
LPB137_08935	ENOG4105CH6	catalase
LPB137_08940	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
LPB137_08950	ENOG4105BZU	Histidine kinase
LPB137_08960	ENOG4108JU6	CBS domain protein
LPB137_08980	ENOG4105KWI	UPF0339 protein
LPB137_09005	ENOG4105DSF	transport protein
LPB137_09025	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
LPB137_09050	ENOG4105FCD	Major Facilitator
LPB137_09060	ENOG4105DR4	Methyltransferase
LPB137_09065	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
LPB137_09070	ENOG4105EI2	Pseudouridine synthase
LPB137_09075	ENOG4105CBC	glutamate synthase
LPB137_09090	ENOG4105BZU	Histidine kinase
LPB137_09125	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
LPB137_09130	ENOG4106GFD	transport protein
LPB137_09135	ENOG4105M8K	biopolymer transport protein
LPB137_09150	ENOG4107F3C	Hemin uptake protein
LPB137_09155	ENOG4105D05	Receptor
LPB137_09160	ENOG4105D05	Receptor
LPB137_09170	ENOG4105C1J	atp-dependent rna helicase
LPB137_09200	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
LPB137_09235	ENOG4105VEQ	Cold shock protein
LPB137_09245	ENOG4105DFI	Membrane
LPB137_09250	ENOG4105VCQ	rubredoxin
LPB137_09255	ENOG4105FE9	pseudouridine synthase
LPB137_09280	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
LPB137_09285	ENOG4105DN9	Na H antiporter
LPB137_09290	ENOG4108IYU	L-aspartate oxidase
LPB137_09305	ENOG4105CHM	Aminotransferase
LPB137_09310	ENOG41076HS	cation diffusion facilitator family transporter
LPB137_09315	ENOG4105MGE	Rhodanese domain protein
LPB137_09320	ENOG4105DHT	Metal Dependent Phosphohydrolase
LPB137_09325	ENOG4105F8J	Adenylate Guanylate cyclase
LPB137_09340	ENOG4105C5H	ABC transporter
LPB137_09350	ENOG4105BZU	Histidine kinase
LPB137_09360	ENOG4105E1F	short-chain dehydrogenase reductase
LPB137_09370	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
LPB137_09375	ENOG4106H78	methyltransferase
LPB137_09380	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
LPB137_09390	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LPB137_09395	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
LPB137_09425	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
LPB137_09435	ENOG41080V7	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
LPB137_09450	ENOG4108RAC	Rubrerythrin
LPB137_09455	ENOG4108RAC	Rubrerythrin
LPB137_09465	ENOG4105CJR	Integral membrane protein (MviN
LPB137_09470	ENOG4105BZ1	(ABC) transporter
LPB137_09475	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
LPB137_09485	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
LPB137_09490	ENOG4105CAN	Short-chain dehydrogenase reductase Sdr
LPB137_09495	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
LPB137_09500	ENOG4105DZP	Membrane-associated zinc metalloprotease
LPB137_09505	ENOG4105DFA	alanine racemase domain protein
LPB137_09515	ENOG4105VSH	4-oxalocrotonate tautomerase
LPB137_09525	ENOG4105DK0	Indole-3-glycerol phosphate synthase
LPB137_09535	ENOG4105QTX	Pfam:UPF0153
LPB137_09540	ENOG41060K3	Methyltransferase
LPB137_09550	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
LPB137_09555	ENOG4105DQU	oxidoreductase, subunit beta
LPB137_09565	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
LPB137_09570	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
LPB137_09575	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
LPB137_09580	ENOG4105DJV	ribulose-phosphate 3-epimerase
LPB137_09585	ENOG4105HDD	phospholipase
LPB137_09595	ENOG4107VIJ	nudix hydrolase
LPB137_09605	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
LPB137_09610	ENOG4108VPT	UPF0234 protein
LPB137_09615	ENOG4105BZU	Histidine kinase
LPB137_09620	ENOG4105C2W	permease
LPB137_09625	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
LPB137_09640	ENOG4105M08	Membrane
LPB137_09650	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
LPB137_09655	ENOG4105C7N	Xanthine uracil vitamin C permease
LPB137_09670	ENOG4105VG1	fes assembly suf system protein
LPB137_09675	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
LPB137_09710	ENOG4105N2G	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LPB137_09715	ENOG4108ZFX	Mannosyl-3-phosphoglycerate phosphatase
LPB137_09720	ENOG4105D1Z	hydroxypyruvate reductase
LPB137_09725	ENOG4105C3Q	Glycosyl transferase, family 2
LPB137_09735	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
LPB137_09745	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
LPB137_09770	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
LPB137_09780	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
LPB137_09795	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
LPB137_09805	ENOG4105VB9	50S ribosomal protein l28
LPB137_09810	ENOG4105CPK	Glycosyl transferase (Group 1
LPB137_09815	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
LPB137_09820	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
LPB137_09825	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
LPB137_09830	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
LPB137_09845	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
LPB137_09880	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
LPB137_09890	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
LPB137_09895	ENOG4105CPK	Glycosyl transferase (Group 1
LPB137_09900	ENOG4105CPK	Glycosyl transferase (Group 1
LPB137_09905	ENOG4105C30	Nad-dependent epimerase dehydratase
LPB137_09910	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
LPB137_09915	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
LPB137_09920	ENOG4107QQG	Dehydrogenase
LPB137_09940	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
LPB137_09950	ENOG4105BZ8	glutamate synthase
LPB137_09955	ENOG4105CBC	glutamate synthase
LPB137_09960	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
LPB137_09965	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
LPB137_09970	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
LPB137_09985	ENOG4105C8Q	Methyl-accepting chemotaxis
LPB137_09995	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
LPB137_10050	ENOG4105EFQ	Two component transcriptional regulator (Winged helix family
LPB137_10115	ENOG4105BZU	Histidine kinase
LPB137_10120	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
LPB137_10125	ENOG4105M7K	Involved in the transcription termination process (By similarity)
LPB137_10130	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
LPB137_10135	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
LPB137_10150	ENOG4105CBC	glutamate synthase
LPB137_10160	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
LPB137_10180	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
LPB137_10220	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
LPB137_10230	ENOG4105RQ9	TPR repeat-containing protein
LPB137_10240	ENOG4105DX0	Hemolysin A
LPB137_10260	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
LPB137_10265	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LPB137_10275	ENOG4105CQB	FAD linked oxidase domain protein
LPB137_10280	ENOG4107S2Z	UPF0761 membrane protein
LPB137_10330	ENOG4105ESV	Glycosyl transferase, family 4
LPB137_10345	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
LPB137_10350	ENOG4107QP8	phosphohexose isomerase
LPB137_10355	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
LPB137_10360	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
LPB137_10370	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
LPB137_10380	ENOG4107TYR	Glycosyl Transferase
LPB137_10410	ENOG4108UW5	maltose o-acetyltransferase
LPB137_10415	ENOG4105Q84	sucrose synthase
LPB137_10455	ENOG4105D75	Capsular exopolysaccharide family
LPB137_10475	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
LPB137_10480	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
LPB137_10485	ENOG4108YZY	peptidylprolyl cis-trans isomerase
LPB137_10495	ENOG4105UYK	outer membrane protein a
LPB137_10500	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
LPB137_10510	ENOG4105M8F	Biopolymer transport protein exbD tolR
LPB137_10515	ENOG4105E02	MotA TolQ exbB proton channel
LPB137_10520	ENOG41082MC	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
LPB137_10525	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
LPB137_10530	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
LPB137_10535	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
LPB137_10540	ENOG4105PQH	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
LPB137_10545	ENOG4105YF2	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
LPB137_10555	ENOG4105FA0	parb-like partition protein
LPB137_10560	ENOG4107QJE	Chromosome Partitioning Protein
LPB137_10575	ENOG4105BZU	Histidine kinase
LPB137_10580	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
LPB137_10585	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
LPB137_10590	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LPB137_10595	ENOG4105K46	50S ribosomal protein l27
LPB137_10600	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
LPB137_10605	ENOG4105KME	endoribonuclease L-psp
LPB137_10610	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
LPB137_10625	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
LPB137_10630	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
LPB137_10635	ENOG4105D0M	Protease HtpX homolog
LPB137_10650	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
LPB137_10660	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
LPB137_10665	ENOG4108512	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
LPB137_10675	ENOG4105VG0	50S ribosomal protein l34
LPB137_10680	ENOG4105BZU	Histidine kinase
LPB137_10685	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
LPB137_10690	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
LPB137_10695	ENOG4105DS4	PAS PAC sensor Signal transduction histidine kinase
LPB137_10705	ENOG4105E0X	reductase
LPB137_10710	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
LPB137_10720	ENOG4109045	doxx family
LPB137_10730	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
LPB137_10735	ENOG4105BZU	Histidine kinase
LPB137_10740	ENOG4105DC1	bifunctional purine biosynthesis protein purh
LPB137_10770	ENOG4108BGM	Quinol dehydrogenase periplasmic component
LPB137_10780	ENOG4106RE7	Cytochrome
LPB137_10790	ENOG4105DA5	(ABC) transporter
LPB137_10800	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
LPB137_10810	ENOG4105E4C	Lytic transglycosylase catalytic
LPB137_10815	ENOG4105CJW	magnesium transporter
LPB137_10820	ENOG4105EUJ	GTP cyclohydrolase i
LPB137_10825	ENOG4105D7Q	type ii secretion system
LPB137_10830	ENOG4107QHF	type ii secretion system protein e
LPB137_10845	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
LPB137_10850	ENOG4105C0P	Mg chelatase subunit ChlI
LPB137_10855	ENOG4107RY6	amino acid
LPB137_10865	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
LPB137_10870	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
LPB137_10875	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
LPB137_10880	ENOG4107QVM	von Willebrand factor, type A
LPB137_10885	ENOG4105CSR	polyphosphate kinase 2
LPB137_10890	ENOG4105CSR	polyphosphate kinase 2
LPB137_10900	ENOG4105VCQ	rubredoxin
LPB137_10920	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
LPB137_11040	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
LPB137_11055	ENOG4105CE1	Ferrous iron transport protein b
LPB137_11070	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
LPB137_11075	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
LPB137_11080	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
LPB137_11085	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
LPB137_11090	ENOG4105F4G	Membrane
LPB137_11100	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
LPB137_11115	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
LPB137_11120	ENOG4105BZU	Histidine kinase
LPB137_11130	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
LPB137_11140	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
LPB137_11145	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
LPB137_11150	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
LPB137_11160	ENOG4105CEY	Amp-dependent synthetase and ligase
LPB137_11165	ENOG4105DJG	MaoC domain protein dehydratase
LPB137_11185	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
LPB137_11190	ENOG4107XC4	flavin reductase domain protein, FMN-binding
LPB137_11195	ENOG4105BZU	Histidine kinase
LPB137_11210	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
LPB137_11225	ENOG4105D7B	Flagellar biosynthesis protein flha
LPB137_11230	ENOG4105DTJ	flagellar hook-associated protein
LPB137_11235	ENOG4108JIR	Flagellum-specific ATP synthase
LPB137_11245	ENOG4105D00	flagellar biosynthetic protein flhB
LPB137_11260	ENOG4108ZC9	flagellar basal-body rod protein flgc
LPB137_11265	ENOG41084DA	flagellar hook-basal body complex protein fliE
LPB137_11275	ENOG4107R21	site-determining protein
LPB137_11280	ENOG4105FZW	flagellar biosynthesis regulator FlhF
LPB137_11295	ENOG4105YKR	
LPB137_11305	ENOG4108217	motA TolQ ExbB proton channel
LPB137_11310	ENOG4105DD5	Flagellar motor switch protein
LPB137_11330	ENOG4105BZE	flagellar hook protein, FlgE
LPB137_11335	ENOG4105BZE	flagellar hook protein, FlgE
LPB137_11340	ENOG4105W00	Flagellar hook capping protein
LPB137_11355	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
LPB137_11360	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
LPB137_11365	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
LPB137_11370	ENOG4105CGA	flagellar basal-body rod protein FlgG
LPB137_11380	ENOG4108VYJ	response regulator receiver protein
LPB137_11385	ENOG4105CGA	flagellar basal-body rod protein FlgG
LPB137_11400	ENOG4105V3S	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
LPB137_11405	ENOG4105VB6	UPF0109 protein
LPB137_11410	ENOG4105K5M	30s ribosomal protein S16
LPB137_11415	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LPB137_11420	ENOG4105C34	Pseudouridine synthase
LPB137_11425	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
LPB137_11435	ENOG4105EGD	dinuclear metal center protein, YbgI family
LPB137_11440	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
LPB137_11445	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
LPB137_11455	ENOG4105CFP	Peptidase U32
LPB137_11465	ENOG41080BE	Methyl-accepting chemotaxis sensory transducer
LPB137_11465	ENOG41080BE	Methyl-accepting chemotaxis sensory transducer
LPB137_11475	ENOG4108EMS	branched-chain alpha-keto acid dehydrogenase subunit E2
LPB137_11515	ENOG41088H4	Diheme cytochrome SoxA (Sulfur oxidation)
LPB137_11540	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
LPB137_11545	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
LPB137_11550	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
LPB137_11555	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
LPB137_11560	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
LPB137_11565	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
LPB137_11585	ENOG4105BZU	Histidine kinase
LPB137_11600	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
LPB137_11605	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
LPB137_11610	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
LPB137_11615	ENOG4108VZM	50s ribosomal protein L10
LPB137_11620	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
LPB137_11625	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
LPB137_11630	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
LPB137_11645	ENOG41086AR	50S ribosomal protein L33
LPB137_11650	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
LPB137_11675	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
LPB137_11680	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
LPB137_11685	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
LPB137_11690	ENOG4108RZA	ABC transporter
LPB137_11695	ENOG4108JQC	penicillin-binding protein 1A
LPB137_11700	ENOG4105C5F	glutamine synthetase
LPB137_11710	ENOG4105BZU	Histidine kinase
LPB137_11715	ENOG4108ZEX	molybdopterin converting factor, subunit 2
LPB137_11725	ENOG4108XUR	Pfam:DUF178
LPB137_11730	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
LPB137_11740	ENOG4105CNI	cell division protein FtsW
LPB137_11745	ENOG4105CJN	penicillin-binding protein
LPB137_11750	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
LPB137_11790	ENOG4105DDQ	anthranilate synthase
LPB137_11815	ENOG41084CK	capsule polysaccharide
LPB137_11820	ENOG4105E12	capsule polysaccharide
LPB137_11840	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
LPB137_11855	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
LPB137_11860	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
LPB137_11870	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
LPB137_11895	ENOG4107V1M	polysaccharide export protein
LPB137_11900	ENOG4105ECX	polysaccharide export
LPB137_11910	ENOG41090SZ	ABC-2 type transporter
LPB137_11925	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
LPB137_11930	ENOG4105BZU	Histidine kinase
LPB137_11935	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
LPB137_11940	ENOG4105C87	Aminotransferase class I and II
LPB137_11945	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
LPB137_11950	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
LPB137_11955	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
LPB137_11960	ENOG4105GKE	subunit e
LPB137_11970	ENOG4105BZN	citrate synthase
LPB137_11980	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
LPB137_11990	ENOG4107YX3	NADH dehydrogenase subunit j
LPB137_11995	ENOG41080EA	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
LPB137_12000	ENOG4105D65	subunit l
LPB137_12005	ENOG4105C8S	subunit m
LPB137_12010	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
LPB137_12015	ENOG4108S24	Fumarate reduCtase
LPB137_12020	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
LPB137_12025	ENOG4105E33	succinate dehydrogenase
LPB137_12035	ENOG410890F	Dynamin family
LPB137_12050	ENOG4105BZU	Histidine kinase
LPB137_12055	ENOG4108VKG	metal-dependent hydrolase
LPB137_12120	ENOG41081FY	multiple antibiotic resistance (MarC)-related
LPB137_12125	ENOG4105E5Q	amino acid AbC transporter
LPB137_12130	ENOG4106PMH	Extracellular solute-binding protein family 3
LPB137_12160	ENOG4108BSC	Methyltransferase
LPB137_12165	ENOG4105C9U	ATP-dependent DNA helicase RecQ
LPB137_12180	ENOG4105C5I	Dehydrogenase
LPB137_12195	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
LPB137_12200	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
LPB137_12210	ENOG4105CR4	methylisocitrate lyase
LPB137_12215	ENOG4105BZN	citrate synthase
LPB137_12220	ENOG4108I0Z	Aconitate hydratase
LPB137_12225	ENOG4105C7F	AcnD-accessory protein PrpF
LPB137_12240	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
LPB137_12250	ENOG4107QMP	dna polymerase iii subunits gamma and tau
LPB137_12255	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
LPB137_12270	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
LPB137_12275	ENOG4105D3R	alkyl hydroperoxide reductase
LPB137_12285	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
LPB137_12295	ENOG4105YQ2	50s ribosomal protein l32
LPB137_12300	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
LPB137_12305	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
LPB137_12310	ENOG4105KMT	branched-chain amino acid
LPB137_12315	ENOG4108UMN	azlc family
LPB137_12335	ENOG4105CRQ	synthase (Component I)
LPB137_12340	ENOG4105CXT	aspartate transcarbamylase
LPB137_12350	ENOG4105C8Y	Acetylornithine aminotransferase
LPB137_12375	ENOG4105BZU	Histidine kinase
LPB137_12380	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
LPB137_12385	ENOG41082UM	UPF0102 protein
LPB137_12400	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
LPB137_12420	ENOG4105DVY	radical SAM domain protein
LPB137_12430	ENOG4105KB8	(LipO)protein
LPB137_12435	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
LPB137_12445	ENOG4105CHV	Transcription elongation factor NusA
LPB137_12450	ENOG4105C8N	cysteinyl-tRNA synthetase
LPB137_12455	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
LPB137_12460	ENOG4108UUM	single-stranded DNA-binding protein
LPB137_12465	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
LPB137_12475	ENOG410821Z	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum (By similarity)
LPB137_12485	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
LPB137_12490	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
LPB137_12505	ENOG4105BZU	Histidine kinase
LPB137_12510	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
LPB137_12515	ENOG4105DFU	Cell wall formation (By similarity)
LPB137_12525	ENOG4105CHM	Aminotransferase
LPB137_12540	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
LPB137_12545	ENOG410855J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
LPB137_12550	ENOG4105KUZ	arsenate reductase
LPB137_12555	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
LPB137_12560	ENOG4107V25	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
LPB137_12565	ENOG4105EAC	phosphoserine phosphatase
LPB137_12575	ENOG4105GSH	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
LPB137_12580	ENOG410829W	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
LPB137_12585	ENOG4105CG5	Glycosyl transferase (Group 1
LPB137_12595	ENOG4107R03	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
LPB137_12600	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
LPB137_12620	ENOG4107TPX	flagellar hook-associated
LPB137_12655	ENOG4105VS8	Flagellar biosynthetic protein fliq
LPB137_12665	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
LPB137_12670	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
LPB137_12675	ENOG4105EKE	dihydroorotase
LPB137_12680	ENOG4108YZA	Nitrogen regulatory protein pii
LPB137_12690	ENOG4108YZA	Nitrogen regulatory protein pii
LPB137_12730	ENOG4105D9P	serine threonine protein kinase
LPB137_12740	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
LPB137_12745	ENOG4108XIB	electron transport protein ysaA
LPB137_12750	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
LPB137_12760	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
LPB137_12780	ENOG4105CQM	Urea amidohydrolase subunit alpha
LPB137_12785	ENOG4108YZ9	Urea amidohydrolase subunit gamma
LPB137_12800	ENOG4108IV0	ABC, transporter
LPB137_12805	ENOG4105C0Z	ABC transporter
LPB137_12815	ENOG4105C32	Amino acid ABC transporter (Permease)
LPB137_12825	ENOG4105BZU	Histidine kinase
LPB137_12835	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
LPB137_12845	ENOG4107QY8	reductase
LPB137_12850	ENOG4105BZU	Histidine kinase
LPB137_12855	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
LPB137_12860	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
LPB137_12865	ENOG4108IFG	nitrite reductase, (NAD(P)H)
LPB137_12875	ENOG4105EFQ	Two component transcriptional regulator (Winged helix family
LPB137_12880	ENOG4105BZU	Histidine kinase
LPB137_12885	ENOG4105TMB	Formate nitrite transporter
LPB137_12890	ENOG4108V7B	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide (By similarity)
LPB137_12895	ENOG4105D9P	serine threonine protein kinase
LPB137_12905	ENOG4105BZU	Histidine kinase
LPB137_12915	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
LPB137_12920	ENOG4105CEY	Amp-dependent synthetase and ligase
LPB137_12925	ENOG4105FR1	rard protein
LPB137_12930	ENOG4107SDU	Methyl-accepting chemotaxis
LPB137_12965	ENOG41085FC	arsR family transcriptional regulator
LPB137_12970	ENOG41067MG	lrgb family
LPB137_12975	ENOG4105VAW	lrga family
LPB137_12990	ENOG4105CV1	Transketolase (EC 2.2.1.1)
LPB137_13005	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
LPB137_13010	ENOG4108JJA	ABC, transporter
LPB137_13055	ENOG4105C01	Dihydroxy-acid dehydratase
LPB137_13060	ENOG4105C0H	protease
LPB137_13065	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
LPB137_13070	ENOG4105BZU	Histidine kinase
LPB137_13075	ENOG4105EMK	carboxylate amino acid amine transporter
LPB137_13085	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
LPB137_13090	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
LPB137_13095	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
LPB137_13095	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
LPB137_13120	ENOG4105CIH	Imidazole acetol-phosphate transaminase
LPB137_13125	ENOG4107XPA	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
LPB137_13135	ENOG41081FY	multiple antibiotic resistance (MarC)-related
LPB137_13140	ENOG4108K7V	UPF0284 protein
LPB137_13145	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
LPB137_13195	ENOG4105CFG	Acts as a chaperone (By similarity)
LPB137_13200	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LPB137_13205	ENOG4108122	heat-inducible transcription repressor
LPB137_13220	ENOG4105I93	response regulator
LPB137_13225	ENOG4105BZU	Histidine kinase
LPB137_13230	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
LPB137_13240	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
LPB137_13245	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
LPB137_13250	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
LPB137_13255	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
LPB137_13265	ENOG4105CB5	ATP-dependent DNA helicase recG
LPB137_13270	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
LPB137_13280	ENOG4105I03	Flagellin
LPB137_13290	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
LPB137_13295	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
LPB137_13315	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
LPB137_13330	ENOG4105D4A	Cell wall formation (By similarity)
LPB137_13335	ENOG4105E63	Pfam:DUF178
LPB137_13345	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
LPB137_13350	ENOG4105C8S	subunit m
LPB137_13355	ENOG4105D65	subunit l
LPB137_13360	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
LPB137_13370	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
LPB137_13375	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
LPB137_13380	ENOG4108IEH	NADH dehydrogenase subunit g
LPB137_13395	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
LPB137_13400	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
LPB137_13405	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
LPB137_13410	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
LPB137_13435	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
LPB137_13485	ENOG4105CSV	Glutaminase
LPB137_13490	ENOG4105CSV	Glutaminase
LPB137_13515	ENOG4105WPN	DNA integration recombination invertion protein
LPB137_13520	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
LPB137_13525	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
LPB137_13530	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
LPB137_13535	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
LPB137_13555	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
LPB137_13575	ENOG4105BZU	Histidine kinase
LPB137_13580	ENOG4105BZU	Histidine kinase
LPB137_13590	ENOG4105C58	cytochrome c oxidase accessory protein ccog
LPB137_13595	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
LPB137_13600	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
LPB137_13615	ENOG4107RKG	DJ-1/PfpI family
LPB137_13630	ENOG4105C0B	DNA polymerase III (alpha subunit)
LPB137_13635	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
LPB137_13660	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
LPB137_13670	ENOG4105E39	Enoyl-CoA hydratase
LPB137_13690	ENOG4105HFZ	Membrane
LPB137_13700	ENOG4105NU9	Preprotein translocase subunit SecG
LPB137_13705	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
LPB137_13710	ENOG4107VCP	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
LPB137_13720	ENOG4105D8G	Major Facilitator superfamily
LPB137_13725	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
LPB137_13730	ENOG410802Z	Protein of unknown function (DUF328)
LPB137_13735	ENOG4105K5B	UPF0225 protein
LPB137_13765	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
LPB137_13770	ENOG4105C26	Dehydrogenase
LPB137_13775	ENOG4105C7K	acetolactate synthase
LPB137_13780	ENOG4108V0P	LemA family
LPB137_13800	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
LPB137_13830	ENOG4105KHC	sulfurtransferase
LPB137_13835	ENOG4105BZU	Histidine kinase
LPB137_13850	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
LPB137_13865	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
LPB137_13910	ENOG4105CBX	hi0933 family
LPB137_13930	ENOG4105C6T	cysteine synthase
LPB137_13945	ENOG4105C11	sulfate adenylyltransferase), subunit 2
LPB137_13950	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
LPB137_13965	ENOG4105CI3	gtp-binding protein typa
LPB137_13970	ENOG4105CSV	Glutaminase
LPB137_13975	ENOG4105EN6	Membrane
LPB137_13990	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)