locus-tag	class	description
AVENP_0001	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AVENP_0002	COG0592	DNA-directed DNA polymerase activity
AVENP_0003	COG0187	DNA topoisomerase II activity
AVENP_0004	COG0492	ferredoxin-NADP+ reductase activity
AVENP_0005	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AVENP_0009	COG0697	spore germination
AVENP_0010	COG1238	metal cluster binding
AVENP_0012	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AVENP_0015	COG5001	Diguanylate cyclase
AVENP_0015	COG5002	protein histidine kinase activity
AVENP_0019	COG1053	succinate dehydrogenase
AVENP_0020	COG0667	Aldo Keto reductase
AVENP_0023	COG4208	sulfate ABC transporter
AVENP_0026	COG0500	methyltransferase
AVENP_0027	COG1120	ATPase activity
AVENP_0032	COG3842	ATPase activity
AVENP_0037	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
AVENP_0038	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
AVENP_0040	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
AVENP_0045	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AVENP_0046	COG0633	Ferredoxin
AVENP_0050	COG0716	FMN binding
AVENP_0057	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
AVENP_0058	COG0840	transmembrane signaling receptor activity
AVENP_0059	COG0840	transmembrane signaling receptor activity
AVENP_0060	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
AVENP_0064	COG0426	domain, Protein
AVENP_0066	COG0535	radical SAM domain protein
AVENP_0069	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AVENP_0075	COG0564	pseudouridine synthase activity
AVENP_0076	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AVENP_0077	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AVENP_0078	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AVENP_0086	COG2954	triphosphatase activity
AVENP_0087	COG1151	hydroxylamine reductase activity
AVENP_0089	COG0493	'glutamate synthase
AVENP_0092	COG0604	alcohol dehydrogenase
AVENP_0094	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AVENP_0095	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AVENP_0100	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AVENP_0101	COG0745	RESPONSE REGULATOR receiver
AVENP_0102	COG3852	Histidine kinase
AVENP_0103	COG1556	Lactate utilization protein
AVENP_0104	COG1139	Iron-sulfur cluster binding protein
AVENP_0105	COG0247	lactate metabolic process
AVENP_0107	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AVENP_0108	COG0511	ligase activity, forming carbon-carbon bonds
AVENP_0109	COG0439	Biotin carboxylase
AVENP_0110	COG0513	Belongs to the DEAD box helicase family
AVENP_0111	COG0306	phosphate transporter
AVENP_0113	COG0367	asparagine synthase
AVENP_0115	COG0778	Nitroreductase
AVENP_0116	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AVENP_0117	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AVENP_0118	COG1053	succinate dehydrogenase
AVENP_0120	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AVENP_0122	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AVENP_0122	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
AVENP_0123	COG1187	pseudouridine synthase activity
AVENP_0124	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AVENP_0124	COG0517	IMP dehydrogenase activity
AVENP_0126	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AVENP_0127	COG0107	imidazoleglycerol-phosphate synthase activity
AVENP_0130	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AVENP_0131	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AVENP_0132	COG0724	RNA recognition motif
AVENP_0133	COG0745	RESPONSE REGULATOR receiver
AVENP_0134	COG0642	Histidine kinase
AVENP_0141	COG0534	Mate efflux family protein
AVENP_0142	COG0460	homoserine dehydrogenase
AVENP_0143	COG0436	Aminotransferase
AVENP_0146	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AVENP_0147	COG0254	rRNA binding
AVENP_0148	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AVENP_0161	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AVENP_0167	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AVENP_0168	COG2992	FlgJ-related protein
AVENP_0169	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AVENP_0170	COG0237	dephospho-CoA kinase activity
AVENP_0171	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AVENP_0172	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AVENP_0175	COG2353	YceI-like domain
AVENP_0176	COG1846	Transcriptional regulator
AVENP_0177	COG1741	Belongs to the pirin family
AVENP_0179	COG2353	YceI-like domain
AVENP_0180	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AVENP_0181	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
AVENP_0182	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AVENP_0184	COG0505	Belongs to the CarA family
AVENP_0185	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AVENP_0187	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AVENP_0187	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AVENP_0190	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AVENP_0191	COG0489	protein tyrosine kinase activity
AVENP_0192	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AVENP_0192	COG0140	phosphoribosyl-ATP diphosphatase activity
AVENP_0196	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AVENP_0197	COG4310	Domain of unknown function (DUF2172)
AVENP_0201	COG1410	methionine synthase
AVENP_0201	COG0646	methionine synthase
AVENP_0202	COG0697	spore germination
AVENP_0204	COG3647	Membrane
AVENP_0205	COG1979	alcohol dehydrogenase
AVENP_0210	COG1854	S-ribosylhomocysteine lyase activity
AVENP_0212	COG1335	isochorismatase
AVENP_0215	COG0842	Transport permease protein
AVENP_0216	COG0842	Transport permease protein
AVENP_0217	COG1131	(ABC) transporter
AVENP_0219	COG0840	transmembrane signaling receptor activity
AVENP_0220	COG0840	transmembrane signaling receptor activity
AVENP_0223	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AVENP_0227	COG3180	Ammonia monooxygenase
AVENP_0228	COG0288	reversible hydration of carbon dioxide
AVENP_0234	COG1013	pyruvate-flavodoxin oxidoreductase activity
AVENP_0237	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AVENP_0238	COG0546	phosphoglycolate phosphatase activity
AVENP_0240	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AVENP_0241	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AVENP_0242	COG2205	protein histidine kinase activity
AVENP_0245	COG0704	Plays a role in the regulation of phosphate uptake
AVENP_0246	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AVENP_0247	COG0581	inorganic phosphate transmembrane transporter activity
AVENP_0248	COG0573	inorganic phosphate transmembrane transporter activity
AVENP_0249	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AVENP_0250	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AVENP_0252	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AVENP_0253	COG0268	Binds directly to 16S ribosomal RNA
AVENP_0254	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AVENP_0255	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AVENP_0256	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AVENP_0258	COG0446	pyridine nucleotide-disulphide oxidoreductase
AVENP_0260	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AVENP_0261	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AVENP_0262	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AVENP_0263	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AVENP_0269	COG0575	Belongs to the CDS family
AVENP_0270	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AVENP_0274	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AVENP_0276	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AVENP_0276	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AVENP_0277	COG1324	tolerance protein
AVENP_0278	COG2022	thiamine diphosphate biosynthetic process
AVENP_0290	COG1271	oxidase subunit
AVENP_0292	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
AVENP_0293	COG0511	ligase activity, forming carbon-carbon bonds
AVENP_0297	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AVENP_0304	COG2274	protein secretion by the type I secretion system
AVENP_0305	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AVENP_0307	COG5002	protein histidine kinase activity
AVENP_0308	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AVENP_0310	COG2084	Dehydrogenase
AVENP_0315	COG1346	cytolysis
AVENP_0316	COG0640	Transcriptional regulator
AVENP_0318	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AVENP_0319	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AVENP_0320	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AVENP_0322	COG1742	UPF0060 membrane protein
AVENP_0326	COG1301	dicarboxylic acid transport
AVENP_0327	COG0659	secondary active sulfate transmembrane transporter activity
AVENP_0330	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AVENP_0335	COG0004	ammonium transporteR
AVENP_0337	COG0004	ammonium transporteR
AVENP_0339	COG0418	dihydroorotase activity
AVENP_0340	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AVENP_0341	COG1706	bacterial-type flagellum-dependent cell motility
AVENP_0348	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AVENP_0350	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AVENP_0353	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AVENP_0354	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AVENP_0355	COG0601	transmembrane transport
AVENP_0357	COG0736	holo-[acyl-carrier-protein] synthase activity
AVENP_0358	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AVENP_0360	COG0560	Phosphoserine phosphatase
AVENP_0361	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AVENP_0362	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
AVENP_0363	COG3248	Nucleoside-binding outer membrane protein
AVENP_0364	COG1393	Belongs to the ArsC family
AVENP_0365	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AVENP_0366	COG0343	queuine tRNA-ribosyltransferase activity
AVENP_0368	COG0436	Aminotransferase
AVENP_0372	COG2861	carbohydrate metabolic process
AVENP_0373	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AVENP_0374	COG0557	exoribonuclease II activity
AVENP_0376	COG0360	Binds together with S18 to 16S ribosomal RNA
AVENP_0377	COG0629	single-stranded DNA binding
AVENP_0378	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AVENP_0379	COG0215	cysteine-tRNA ligase activity
AVENP_0380	COG0195	Participates in both transcription termination and antitermination
AVENP_0382	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AVENP_0383	COG2121	Domain of unknown function (DUF374)
AVENP_0385	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
AVENP_0387	COG0288	reversible hydration of carbon dioxide
AVENP_0388	COG0156	8-amino-7-oxononanoate synthase activity
AVENP_0389	COG0792	nuclease activity
AVENP_0396	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AVENP_0398	COG0540	Belongs to the ATCase OTCase family
AVENP_0399	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AVENP_0400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AVENP_0403	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AVENP_0404	COG1687	branched-chain amino acid
AVENP_0405	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AVENP_0406	COG0416	fatty acid biosynthetic process
AVENP_0407	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AVENP_0409	COG0105	UTP biosynthetic process
AVENP_0411	COG0450	alkyl hydroperoxide reductase
AVENP_0412	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AVENP_0413	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AVENP_0414	COG2011	ABC-type metal ion transport system permease component
AVENP_0416	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AVENP_0417	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AVENP_0418	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AVENP_0420	COG0181	hydroxymethylbilane synthase activity
AVENP_0423	COG2828	Protein conserved in bacteria
AVENP_0424	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AVENP_0426	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AVENP_0433	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AVENP_0434	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AVENP_0437	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AVENP_0438	COG0601	transmembrane transport
AVENP_0439	COG4166	transmembrane transport
AVENP_0442	COG0514	ATP-dependent DNA helicase (RecQ)
AVENP_0444	COG0640	Transcriptional regulator
AVENP_0445	COG2217	Heavy metal translocating P-type atpase
AVENP_0448	COG1451	nucleotide metabolic process
AVENP_0455	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AVENP_0456	COG1053	succinate dehydrogenase
AVENP_0458	COG1007	ATP synthesis coupled electron transport
AVENP_0460	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AVENP_0461	COG0713	ATP synthesis coupled electron transport
AVENP_0462	COG0839	Belongs to the complex I subunit 6 family
AVENP_0463	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AVENP_0464	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AVENP_0466	COG0372	Belongs to the citrate synthase family
AVENP_0469	COG0649	NAD binding
AVENP_0469	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AVENP_0470	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AVENP_0471	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AVENP_0472	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AVENP_0473	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AVENP_0474	COG3610	response to peptide
AVENP_0475	COG3610	response to peptide
AVENP_0477	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AVENP_0478	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AVENP_0482	COG1971	Probably functions as a manganese efflux pump
AVENP_0485	COG1132	(ABC) transporter
AVENP_0487	COG4771	TonB-dependent receptor
AVENP_0492	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AVENP_0495	COG1280	lysine exporter protein (LysE YggA)
AVENP_0496	COG0840	transmembrane signaling receptor activity
AVENP_0497	COG1760	l-serine dehydratase
AVENP_0498	COG1280	lysine exporter protein (LysE YggA)
AVENP_0499	COG1126	abc transporter atp-binding protein
AVENP_0500	COG0765	amino acid transport
AVENP_0501	COG4597	amino acid ABC transporter
AVENP_0502	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AVENP_0503	COG0840	transmembrane signaling receptor activity
AVENP_0507	COG3043	anaerobic respiration
AVENP_0508	COG0348	domain, Protein
AVENP_0509	COG0437	4 iron, 4 sulfur cluster binding
AVENP_0510	COG0243	molybdopterin cofactor binding
AVENP_0511	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AVENP_0511	COG1648	precorrin-2 dehydrogenase activity
AVENP_0514	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AVENP_0515	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AVENP_0516	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AVENP_0518	COG2404	hydrolase activity, acting on ester bonds
AVENP_0519	COG1832	CoA-binding protein
AVENP_0520	COG0642	Histidine kinase
AVENP_0521	COG0745	RESPONSE REGULATOR receiver
AVENP_0522	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AVENP_0523	COG0191	fructose-bisphosphate aldolase activity
AVENP_0524	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AVENP_0528	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AVENP_0535	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AVENP_0538	COG0535	radical SAM domain protein
AVENP_0539	COG3842	ATPase activity
AVENP_0541	COG1177	transmembrane transport
AVENP_0542	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AVENP_0543	COG0745	RESPONSE REGULATOR receiver
AVENP_0544	COG2205	protein histidine kinase activity
AVENP_0544	COG0784	Response regulator, receiver
AVENP_0547	COG1278	Cold shock
AVENP_0548	COG0848	biopolymer transport protein
AVENP_0549	COG0811	peptide transport
AVENP_0551	COG4191	Histidine kinase
AVENP_0554	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AVENP_0556	COG0142	geranyltranstransferase activity
AVENP_0557	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AVENP_0558	COG0442	prolyl-tRNA aminoacylation
AVENP_0559	COG0668	transmembrane transport
AVENP_0560	COG0617	tRNA 3'-terminal CCA addition
AVENP_0563	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AVENP_0564	COG1862	Preprotein translocase
AVENP_0565	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AVENP_0566	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AVENP_0570	COG0495	leucyl-tRNA aminoacylation
AVENP_0572	COG0285	dihydrofolate synthase activity
AVENP_0575	COG0848	biopolymer transport protein
AVENP_0576	COG0811	peptide transport
AVENP_0580	COG0577	efflux transmembrane transporter activity
AVENP_0580	COG1136	(ABC) transporter
AVENP_0581	COG1136	(ABC) transporter
AVENP_0581	COG0577	efflux transmembrane transporter activity
AVENP_0582	COG0666	response to abiotic stimulus
AVENP_0591	COG0735	belongs to the Fur family
AVENP_0599	COG0114	fumarate hydratase activity
AVENP_0601	COG3852	Histidine kinase
AVENP_0602	COG0745	RESPONSE REGULATOR receiver
AVENP_0603	COG0604	alcohol dehydrogenase
AVENP_0604	COG1733	regulation of RNA biosynthetic process
AVENP_0605	COG0840	transmembrane signaling receptor activity
AVENP_0615	COG4774	siderophore transport
AVENP_0616	COG3128	pkhd-type hydroxylase
AVENP_0623	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AVENP_0624	COG0418	dihydroorotase activity
AVENP_0625	COG0720	synthase
AVENP_0634	COG0737	Belongs to the 5'-nucleotidase family
AVENP_0637	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
AVENP_0645	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AVENP_0649	COG4251	negative regulation of phosphorylation
AVENP_0649	COG5001	Diguanylate cyclase
AVENP_0649	COG3706	GGDEF domain
AVENP_0649	COG2203	Gaf domain
AVENP_0651	COG0745	RESPONSE REGULATOR receiver
AVENP_0652	COG0642	Histidine kinase
AVENP_0653	COG2081	HI0933 family
AVENP_0654	COG0840	transmembrane signaling receptor activity
AVENP_0657	COG5000	phosphorelay sensor kinase activity
AVENP_0658	COG1692	metallophosphoesterase
AVENP_0662	COG2226	methyltransferase
AVENP_0663	COG1570	exodeoxyribonuclease VII activity
AVENP_0664	COG0835	chemotaxis
AVENP_0668	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AVENP_0669	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AVENP_0671	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AVENP_0672	COG0459	protein refolding
AVENP_0674	COG0745	RESPONSE REGULATOR receiver
AVENP_0675	COG1408	metallophosphoesterase
AVENP_0677	COG2353	YceI-like domain
AVENP_0680	COG1136	(ABC) transporter
AVENP_0680	COG0577	efflux transmembrane transporter activity
AVENP_0683	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AVENP_0686	COG2962	Rard protein
AVENP_0687	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AVENP_0688	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AVENP_0690	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AVENP_0692	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AVENP_0693	COG2264	protein methyltransferase activity
AVENP_0694	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AVENP_0698	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AVENP_0699	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AVENP_0704	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AVENP_0716	COG1132	(ABC) transporter
AVENP_0719	COG3706	GGDEF domain
AVENP_0720	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AVENP_0721	COG1090	epimerase
AVENP_0722	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AVENP_0724	COG0840	transmembrane signaling receptor activity
AVENP_0728	COG0481	GTPase activity
AVENP_0731	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AVENP_0733	COG0482	sulfurtransferase activity
AVENP_0735	COG0482	sulfurtransferase activity
AVENP_0736	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AVENP_0737	COG0006	proline dipeptidase activity
AVENP_0738	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AVENP_0739	COG0402	S-adenosylhomocysteine deaminase activity
AVENP_0740	COG0616	signal peptide processing
AVENP_0742	COG0280	phosphate acetyltransferase
AVENP_0743	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AVENP_0744	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AVENP_0745	COG2176	DNA-directed DNA polymerase activity
AVENP_0749	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AVENP_0753	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AVENP_0755	COG0745	RESPONSE REGULATOR receiver
AVENP_0756	COG5002	protein histidine kinase activity
AVENP_0765	COG1546	Belongs to the CinA family
AVENP_0765	COG1058	Belongs to the CinA family
AVENP_0766	COG0579	oxidoreductase
AVENP_0767	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AVENP_0771	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AVENP_0773	COG0052	Belongs to the universal ribosomal protein uS2 family
AVENP_0774	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AVENP_0775	COG1136	(ABC) transporter
AVENP_0777	COG0194	GDP metabolic process
AVENP_0778	COG5001	Diguanylate cyclase
AVENP_0778	COG5002	protein histidine kinase activity
AVENP_0779	COG2217	Heavy metal translocating P-type atpase
AVENP_0782	COG4608	Belongs to the ABC transporter superfamily
AVENP_0783	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AVENP_0786	COG1355	regulation of microtubule-based process
AVENP_0787	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AVENP_0788	COG1121	(ABC) transporter
AVENP_0789	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AVENP_0791	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AVENP_0792	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
AVENP_0794	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AVENP_0796	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AVENP_0798	COG0004	ammonium transporteR
AVENP_0800	COG0210	DNA helicase
AVENP_0801	COG0569	domain protein
AVENP_0801	COG0475	glutathione-regulated potassium exporter activity
AVENP_0802	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AVENP_0807	COG3258	Cytochrome c
AVENP_0814	COG0693	protein deglycase activity
AVENP_0817	COG0525	valine-tRNA ligase activity
AVENP_0820	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AVENP_0823	COG1047	Peptidyl-prolyl cis-trans
AVENP_0829	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AVENP_0832	COG2814	Major facilitator Superfamily
AVENP_0833	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AVENP_0836	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AVENP_0838	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AVENP_0839	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AVENP_0847	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AVENP_0848	COG1309	transcriptional regulator
AVENP_0857	COG0439	Biotin carboxylase
AVENP_0859	COG3177	Filamentation induced by cAMP protein fic
AVENP_0862	COG2166	iron-sulfur cluster assembly
AVENP_0863	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AVENP_0865	COG0396	ATPase activity
AVENP_0866	COG0719	Fe-S assembly protein
AVENP_0868	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AVENP_0868	COG2906	2 iron, 2 sulfur cluster binding
AVENP_0868	COG0822	iron-sulfur transferase activity
AVENP_0869	COG1280	lysine exporter protein (LysE YggA)
AVENP_0871	COG2239	Acts as a magnesium transporter
AVENP_0872	COG0165	Argininosuccinate lyase
AVENP_0873	COG0835	chemotaxis
AVENP_0873	COG0784	Response regulator, receiver
AVENP_0874	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AVENP_0875	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AVENP_0876	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AVENP_0879	COG0556	nucleotide-excision repair
AVENP_0883	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AVENP_0891	COG0698	ribose 5-phosphate isomerase
AVENP_0892	COG0681	Belongs to the peptidase S26 family
AVENP_0893	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AVENP_0894	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AVENP_0895	COG0193	aminoacyl-tRNA hydrolase activity
AVENP_0898	COG0860	N-Acetylmuramoyl-L-alanine amidase
AVENP_0900	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AVENP_0901	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AVENP_0903	COG0528	UMP kinase activity
AVENP_0905	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AVENP_0906	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AVENP_0907	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AVENP_0909	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AVENP_0910	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AVENP_0913	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AVENP_0914	COG0305	Participates in initiation and elongation during chromosome replication
AVENP_0916	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AVENP_0918	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AVENP_0919	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AVENP_0920	COG1088	dTDP-glucose 4,6-dehydratase activity
AVENP_0921	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AVENP_0922	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AVENP_0939	COG1063	alcohol dehydrogenase
AVENP_0943	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AVENP_0944	COG1086	Polysaccharide biosynthesis protein
AVENP_0946	COG1793	dna ligase
AVENP_0947	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AVENP_0948	COG0133	tryptophan synthase activity
AVENP_0950	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AVENP_0952	COG1979	alcohol dehydrogenase
AVENP_0953	COG0667	Aldo Keto reductase
AVENP_0955	COG0500	methyltransferase
AVENP_0956	COG2207	Transcriptional regulator
AVENP_0959	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
AVENP_0961	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AVENP_0968	COG0012	GTP binding
AVENP_0972	COG3123	guanosine phosphorylase activity
AVENP_0974	COG3278	Belongs to the heme-copper respiratory oxidase family
AVENP_0978	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AVENP_0979	COG0840	transmembrane signaling receptor activity
AVENP_0980	COG0840	transmembrane signaling receptor activity
AVENP_0981	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AVENP_0986	COG0583	DNA-binding transcription factor activity
AVENP_0987	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AVENP_0988	COG0066	3-isopropylmalate dehydratase activity
AVENP_0990	COG4974	Belongs to the 'phage' integrase family
AVENP_1024	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AVENP_1025	COG0585	pseudouridine synthase activity
AVENP_1027	COG0840	transmembrane signaling receptor activity
AVENP_1028	COG0632	four-way junction helicase activity
AVENP_1029	COG1181	Belongs to the D-alanine--D-alanine ligase family
AVENP_1031	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AVENP_1034	COG0840	transmembrane signaling receptor activity
AVENP_1035	COG0840	transmembrane signaling receptor activity
AVENP_1036	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AVENP_1037	COG0051	transcription antitermination factor activity, RNA binding
AVENP_1038	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AVENP_1039	COG0088	Forms part of the polypeptide exit tunnel
AVENP_1040	COG0089	rRNA binding
AVENP_1041	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AVENP_1042	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AVENP_1043	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AVENP_1044	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AVENP_1045	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AVENP_1046	COG0255	Belongs to the universal ribosomal protein uL29 family
AVENP_1047	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AVENP_1048	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AVENP_1049	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AVENP_1050	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AVENP_1051	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AVENP_1052	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AVENP_1053	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AVENP_1054	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AVENP_1055	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AVENP_1056	COG0200	Binds to the 23S rRNA
AVENP_1057	COG0201	protein transport
AVENP_1058	COG0024	Methionine aminopeptidase
AVENP_1059	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AVENP_1061	COG1573	uracil-dna glycosylase
AVENP_1063	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AVENP_1066	COG1032	radical SAM domain protein
AVENP_1067	COG1280	lysine exporter protein (LysE YggA)
AVENP_1069	COG0563	adenylate kinase activity
AVENP_1072	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AVENP_1073	COG0322	excinuclease ABC activity
AVENP_1076	COG3201	nicotinamide mononucleotide transporter
AVENP_1077	COG0386	Belongs to the glutathione peroxidase family
AVENP_1078	COG0840	transmembrane signaling receptor activity
AVENP_1079	COG0840	transmembrane signaling receptor activity
AVENP_1083	COG1360	Flagellar Motor Protein
AVENP_1084	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AVENP_1085	COG0745	RESPONSE REGULATOR receiver
AVENP_1086	COG0745	RESPONSE REGULATOR receiver
AVENP_1087	COG0784	Response regulator, receiver
AVENP_1087	COG2205	protein histidine kinase activity
AVENP_1090	COG0581	inorganic phosphate transmembrane transporter activity
AVENP_1091	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AVENP_1097	COG4773	Receptor
AVENP_1103	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AVENP_1108	COG0829	nickel cation binding
AVENP_1109	COG2252	PERMEase
AVENP_1111	COG0765	amino acid transport
AVENP_1112	COG0765	amino acid transport
AVENP_1116	COG4266	Belongs to the allantoicase family
AVENP_1118	COG0831	urea catabolic process
AVENP_1118	COG0832	Belongs to the urease beta subunit family
AVENP_1119	COG0804	urea catabolic process
AVENP_1120	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
AVENP_1122	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AVENP_1123	COG0745	RESPONSE REGULATOR receiver
AVENP_1128	COG0840	transmembrane signaling receptor activity
AVENP_1130	COG1309	transcriptional regulator
AVENP_1136	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AVENP_1137	COG4565	transcriptional regulatory protein
AVENP_1143	COG3383	formate dehydrogenase (NAD+) activity
AVENP_1143	COG0243	molybdopterin cofactor binding
AVENP_1144	COG0437	4 iron, 4 sulfur cluster binding
AVENP_1146	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AVENP_1150	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AVENP_1151	COG3501	Rhs element vgr protein
AVENP_1153	COG3179	chitinase
AVENP_1156	COG0251	oxidation-reduction process
AVENP_1157	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AVENP_1158	COG1115	amino acid carrier protein
AVENP_1159	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AVENP_1160	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AVENP_1161	COG0328	RNA-DNA hybrid ribonuclease activity
AVENP_1162	COG0840	transmembrane signaling receptor activity
AVENP_1169	COG3437	response regulator, receiver
AVENP_1169	COG0784	Response regulator, receiver
AVENP_1172	COG1944	ATP diphosphatase activity
AVENP_1176	COG0513	Belongs to the DEAD box helicase family
AVENP_1181	COG2258	MOSC domain
AVENP_1182	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AVENP_1183	COG0519	Catalyzes the synthesis of GMP from XMP
AVENP_1184	COG2169	Transcriptional regulator
AVENP_1184	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AVENP_1185	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AVENP_1187	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AVENP_1187	COG0475	glutathione-regulated potassium exporter activity
AVENP_1192	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AVENP_1194	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AVENP_1197	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AVENP_1202	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AVENP_1203	COG1611	Belongs to the LOG family
AVENP_1207	COG0217	transcriptional regulatory protein
AVENP_1211	COG1960	acyl-CoA dehydrogenase activity
AVENP_1212	COG1250	3-hydroxyacyl-CoA dehydrogenase
AVENP_1212	COG1024	Enoyl-CoA hydratase
AVENP_1213	COG0183	Belongs to the thiolase family
AVENP_1214	COG1022	Amp-dependent synthetase and ligase
AVENP_1217	COG0242	peptide deformylase activity
AVENP_1219	COG1049	propionate catabolic process, 2-methylcitrate cycle
AVENP_1220	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AVENP_1221	COG1301	dicarboxylic acid transport
AVENP_1222	COG0697	spore germination
AVENP_1223	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AVENP_1226	COG2095	MarC family integral membrane protein
AVENP_1233	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AVENP_1234	COG1121	(ABC) transporter
AVENP_1240	COG2203	Gaf domain
AVENP_1240	COG2199	diguanylate cyclase activity
AVENP_1243	COG3259	Nickel-dependent hydrogenase
AVENP_1244	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
AVENP_1245	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
AVENP_1254	COG4774	siderophore transport
AVENP_1255	COG2207	Transcriptional regulator
AVENP_1256	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AVENP_1257	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
AVENP_1258	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
AVENP_1273	COG0301	tRNA thio-modification
AVENP_1273	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AVENP_1277	COG2056	Na+-H+ antiporter family
AVENP_1280	COG0596	Alpha beta hydrolase
AVENP_1282	COG0384	phenazine biosynthesis protein PhzF
AVENP_1284	COG2814	Major facilitator Superfamily
AVENP_1287	COG2354	Protein conserved in bacteria
AVENP_1289	COG2081	HI0933 family
AVENP_1291	COG0840	transmembrane signaling receptor activity
AVENP_1293	COG0310	cobalt ion transport
AVENP_1299	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AVENP_1301	COG4804	nuclease activity
AVENP_1305	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AVENP_1306	COG0298	carbon dioxide binding
AVENP_1308	COG2084	Dehydrogenase
AVENP_1310	COG1401	restriction endodeoxyribonuclease activity
AVENP_1312	COG0309	Hydrogenase expression formation protein (HypE)
AVENP_1318	COG0410	ABC transporter
AVENP_1319	COG3706	GGDEF domain
AVENP_1324	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AVENP_1325	COG2171	N-acyltransferase activity
AVENP_1326	COG0488	(ABC) transporter
AVENP_1328	COG1671	Belongs to the UPF0178 family
AVENP_1331	COG2884	Cell division ATP-binding protein ftsE
AVENP_1332	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AVENP_1334	COG0564	pseudouridine synthase activity
AVENP_1335	COG0772	Belongs to the SEDS family
AVENP_1338	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AVENP_1339	COG3123	guanosine phosphorylase activity
AVENP_1343	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AVENP_1344	COG0066	3-isopropylmalate dehydratase activity
AVENP_1345	COG0473	3-isopropylmalate dehydrogenase activity
AVENP_1348	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AVENP_1349	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AVENP_1350	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AVENP_1351	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AVENP_1352	COG0202	RNA polymerase activity
AVENP_1353	COG0203	ribosomal protein L17
AVENP_1354	COG0154	amidase activity
AVENP_1355	COG0517	IMP dehydrogenase activity
AVENP_1355	COG0516	GMP reductase activity
AVENP_1357	COG2827	Endonuclease containing a URI domain
AVENP_1359	COG1047	Peptidyl-prolyl cis-trans
AVENP_1360	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AVENP_1361	COG2040	homocysteine
AVENP_1362	COG1280	lysine exporter protein (LysE YggA)
AVENP_1369	COG0189	ligase activity
AVENP_1369	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AVENP_1373	COG1620	l-lactate permease
AVENP_1375	COG0484	heat shock protein binding
AVENP_1378	COG1472	Belongs to the glycosyl hydrolase 3 family
AVENP_1379	COG0628	permease
AVENP_1380	COG1132	(ABC) transporter
AVENP_1384	COG0745	RESPONSE REGULATOR receiver
AVENP_1385	COG0642	Histidine kinase
AVENP_1388	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AVENP_1394	COG1373	ATPase (AAA superfamily
AVENP_1397	COG3279	Response regulator of the LytR AlgR family
AVENP_1399	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AVENP_1400	COG0513	Belongs to the DEAD box helicase family
AVENP_1401	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AVENP_1403	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AVENP_1404	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AVENP_1406	COG0521	Mo-molybdopterin cofactor biosynthetic process
AVENP_1407	COG0471	metal ion transport
AVENP_1409	COG2200	EAL domain
AVENP_1409	COG2199	diguanylate cyclase activity
AVENP_1409	COG3287	FIST C domain
AVENP_1411	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AVENP_1414	COG3040	lipid binding
AVENP_1416	COG4221	oxidoreductase activity
AVENP_1418	COG0488	(ABC) transporter
AVENP_1419	COG1607	acyl-coa hydrolase
AVENP_1420	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AVENP_1426	COG4206	TonB-dependent receptor
AVENP_1427	COG4607	ABC-type enterochelin transport system periplasmic component
AVENP_1429	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AVENP_1430	COG0588	phosphoglycerate mutase activity
AVENP_1431	COG1797	cobyrinic acid a,c-diamide synthase activity
AVENP_1436	COG1193	negative regulation of DNA recombination
AVENP_1440	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AVENP_1447	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AVENP_1448	COG0789	Transcriptional regulator
AVENP_1449	COG0484	heat shock protein binding
AVENP_1452	COG2201	protein-glutamate methylesterase activity
AVENP_1456	COG1376	ErfK ybiS ycfS ynhG family protein
AVENP_1456	COG1388	LysM domain
AVENP_1458	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AVENP_1461	COG1696	Membrane protein involved in D-alanine export
AVENP_1462	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AVENP_1464	COG0776	regulation of translation
AVENP_1466	COG0275	rRNA processing
AVENP_1474	COG4865	methylaspartate mutase activity
AVENP_1477	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AVENP_1479	COG4591	ABC-type transport system involved in lipoprotein release permease component
AVENP_1480	COG0653	protein targeting
AVENP_1483	COG0582	viral genome integration into host DNA
AVENP_1502	COG2195	Cleaves the N-terminal amino acid of tripeptides
AVENP_1505	COG1333	cytochrome c biogenesis protein
AVENP_1505	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AVENP_1506	COG0500	methyltransferase
AVENP_1507	COG3706	GGDEF domain
AVENP_1507	COG4251	negative regulation of phosphorylation
AVENP_1507	COG5001	Diguanylate cyclase
AVENP_1507	COG2203	Gaf domain
AVENP_1508	COG5001	Diguanylate cyclase
AVENP_1509	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AVENP_1513	COG0133	tryptophan synthase activity
AVENP_1515	COG0484	heat shock protein binding
AVENP_1516	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AVENP_1518	COG0840	transmembrane signaling receptor activity
AVENP_1521	COG0745	RESPONSE REGULATOR receiver
AVENP_1522	COG4191	Histidine kinase
AVENP_1523	COG2205	protein histidine kinase activity
AVENP_1524	COG0745	RESPONSE REGULATOR receiver
AVENP_1525	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AVENP_1526	COG0569	domain protein
AVENP_1531	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AVENP_1532	COG0137	argininosuccinate synthase activity
AVENP_1537	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AVENP_1538	COG0802	atpase or kinase
AVENP_1539	COG1137	ATPase activity
AVENP_1540	COG3706	GGDEF domain
AVENP_1541	COG2199	diguanylate cyclase activity
AVENP_1541	COG2200	EAL domain
AVENP_1541	COG3287	FIST C domain
AVENP_1542	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AVENP_1543	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AVENP_1543	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AVENP_1547	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AVENP_1550	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AVENP_1556	COG0733	neurotransmitter:sodium symporter activity
AVENP_1559	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AVENP_1560	COG0805	protein transport
AVENP_1561	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AVENP_1562	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AVENP_1566	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AVENP_1567	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AVENP_1568	COG1663	tetraacyldisaccharide 4'-kinase activity
AVENP_1570	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AVENP_1571	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AVENP_1572	COG1328	CTP reductase activity
AVENP_1572	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AVENP_1575	COG0745	RESPONSE REGULATOR receiver
AVENP_1576	COG0840	transmembrane signaling receptor activity
AVENP_1577	COG0113	porphobilinogen synthase activity
AVENP_1578	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AVENP_1579	COG0357	Ribosomal RNA small subunit methyltransferase G
AVENP_1590	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
AVENP_1591	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
AVENP_1592	COG0511	ligase activity, forming carbon-carbon bonds
AVENP_1596	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AVENP_1596	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AVENP_1598	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AVENP_1604	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AVENP_1605	COG0612	Peptidase, M16
AVENP_1606	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
AVENP_1607	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AVENP_1608	COG0287	Prephenate dehydrogenase
AVENP_1609	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AVENP_1612	COG0527	aspartate kinase activity
AVENP_1613	COG0494	nUDIX hydrolase
AVENP_1614	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AVENP_1615	COG2890	protein-(glutamine-N5) methyltransferase activity
AVENP_1616	COG0339	signal peptide processing
AVENP_1620	COG0582	viral genome integration into host DNA
AVENP_1631	COG1450	Type ii and iii secretion system protein
AVENP_1638	COG2201	protein-glutamate methylesterase activity
AVENP_1639	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AVENP_1640	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AVENP_1641	COG0643	Histidine kinase
AVENP_1641	COG2198	Histidine kinase
AVENP_1643	COG1185	polyribonucleotide nucleotidyltransferase activity
AVENP_1645	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AVENP_1649	COG0659	secondary active sulfate transmembrane transporter activity
AVENP_1650	COG1160	GTP binding
AVENP_1653	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AVENP_1654	COG1749	Flagellar hook protein flgE
AVENP_1657	COG1749	Flagellar hook protein flgE
AVENP_1659	COG0642	Histidine kinase
AVENP_1660	COG0745	RESPONSE REGULATOR receiver
AVENP_1661	COG1196	nuclear chromosome segregation
AVENP_1661	COG1674	ftsk spoiiie
AVENP_1662	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AVENP_1663	COG0440	acetolactate synthase activity
AVENP_1664	COG0028	Belongs to the TPP enzyme family
AVENP_1669	COG0848	biopolymer transport protein
AVENP_1670	COG0811	peptide transport
AVENP_1673	COG0840	transmembrane signaling receptor activity
AVENP_1680	COG0419	ATPase involved in DNA repair
AVENP_1682	COG2207	Transcriptional regulator
AVENP_1685	COG0450	alkyl hydroperoxide reductase
AVENP_1688	COG1342	Belongs to the UPF0251 family
AVENP_1690	COG1271	oxidase subunit
AVENP_1694	COG0330	HflC and HflK could
AVENP_1695	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
AVENP_1697	COG0745	RESPONSE REGULATOR receiver
AVENP_1698	COG0840	transmembrane signaling receptor activity
AVENP_1701	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AVENP_1702	COG0788	formyltetrahydrofolate deformylase activity
AVENP_1703	COG0281	malic enzyme
AVENP_1703	COG0280	phosphate acetyltransferase
AVENP_1704	COG1027	Aspartate ammonia-lyase
AVENP_1705	COG3852	Histidine kinase
AVENP_1706	COG0745	RESPONSE REGULATOR receiver
AVENP_1709	COG4106	trans-aconitate 2-methyltransferase activity
AVENP_1710	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AVENP_1715	COG0754	glutathionylspermidine amidase activity
AVENP_1718	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AVENP_1722	COG4251	negative regulation of phosphorylation
AVENP_1722	COG5001	Diguanylate cyclase
AVENP_1722	COG3706	GGDEF domain
AVENP_1722	COG2203	Gaf domain
AVENP_1726	COG0037	tRNA processing
AVENP_1730	COG0701	Predicted permease
AVENP_1731	COG1322	Protein conserved in bacteria
AVENP_1732	COG0501	Belongs to the peptidase M48B family
AVENP_1734	COG0824	Thioesterase
AVENP_1737	COG0840	transmembrane signaling receptor activity
AVENP_1738	COG0667	Aldo Keto reductase
AVENP_1752	COG1733	regulation of RNA biosynthetic process
AVENP_1753	COG2249	NAD(P)H dehydrogenase (quinone) activity
AVENP_1754	COG3046	protein related to deoxyribodipyrimidine photolyase
AVENP_1755	COG3040	lipid binding
AVENP_1760	COG4753	response regulator
AVENP_1760	COG2207	Transcriptional regulator
AVENP_1768	COG3501	Rhs element vgr protein
AVENP_1770	COG0778	Nitroreductase
AVENP_1774	COG0778	Nitroreductase
AVENP_1775	COG2249	NAD(P)H dehydrogenase (quinone) activity
AVENP_1776	COG1733	regulation of RNA biosynthetic process
AVENP_1780	COG2855	membrane
AVENP_1781	COG0583	DNA-binding transcription factor activity
AVENP_1784	COG3706	GGDEF domain
AVENP_1789	COG2249	NAD(P)H dehydrogenase (quinone) activity
AVENP_1790	COG1733	regulation of RNA biosynthetic process
AVENP_1795	COG2824	Alkylphosphonate utilization operon protein PhnA
AVENP_1798	COG0488	(ABC) transporter
AVENP_1800	COG0596	Alpha beta hydrolase
AVENP_1802	COG0077	Prephenate dehydratase
AVENP_1802	COG1605	Chorismate mutase
AVENP_1804	COG1119	ATPase activity
AVENP_1805	COG1696	Membrane protein involved in D-alanine export
AVENP_1808	COG2192	nodulation
AVENP_1812	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AVENP_1814	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AVENP_1816	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AVENP_1819	COG2003	Belongs to the UPF0758 family
AVENP_1820	COG1722	exodeoxyribonuclease VII activity
AVENP_1821	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AVENP_1826	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AVENP_1827	COG0849	cell division
AVENP_1836	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AVENP_1838	COG0768	penicillin binding
AVENP_1840	COG5000	phosphorelay sensor kinase activity
AVENP_1841	COG2897	thiosulfate sulfurtransferase activity
AVENP_1849	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AVENP_1852	COG0456	acetyltransferase
AVENP_1853	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AVENP_1856	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AVENP_1857	COG0131	Imidazoleglycerol-phosphate dehydratase
AVENP_1858	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AVENP_1860	COG0084	hydrolase, TatD family'
AVENP_1862	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AVENP_1863	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AVENP_1864	COG0359	binds to the 23S rRNA
AVENP_1866	COG0163	prenyltransferase activity
AVENP_1867	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AVENP_1868	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AVENP_1869	COG0124	histidyl-tRNA synthetase
AVENP_1870	COG1166	arginine decarboxylase activity
AVENP_1871	COG1045	serine acetyltransferase
AVENP_1873	COG0513	Belongs to the DEAD box helicase family
AVENP_1876	COG1309	transcriptional regulator
AVENP_1878	COG1012	belongs to the aldehyde dehydrogenase family
AVENP_1879	COG1881	PFAM PEBP family protein
AVENP_1880	COG1609	Transcriptional regulator
AVENP_1880	COG2207	Transcriptional regulator
AVENP_1883	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
AVENP_1885	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AVENP_1888	COG0475	glutathione-regulated potassium exporter activity
AVENP_1888	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AVENP_1889	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AVENP_1890	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AVENP_1897	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AVENP_1898	COG0508	dehydrogenase complex catalyzes the overall conversion of
AVENP_1899	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AVENP_1900	COG0095	Lipoate-protein ligase
AVENP_1901	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AVENP_1902	COG0039	L-malate dehydrogenase activity
AVENP_1903	COG0628	permease
AVENP_1906	COG2989	Protein conserved in bacteria
AVENP_1907	COG1253	flavin adenine dinucleotide binding
AVENP_1913	COG1028	Short-chain dehydrogenase reductase Sdr
AVENP_1914	COG2807	transmembrane transport
AVENP_1915	COG2186	Transcriptional regulator
AVENP_1916	COG2223	nitrite transmembrane transporter activity
AVENP_1917	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
AVENP_1919	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AVENP_1922	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AVENP_1927	COG0564	pseudouridine synthase activity
AVENP_1930	COG1280	lysine exporter protein (LysE YggA)
AVENP_1931	COG1489	DNA binding
AVENP_1936	COG2814	Major facilitator Superfamily
AVENP_1938	COG1538	Outer membrane efflux protein
AVENP_1947	COG1187	pseudouridine synthase activity
AVENP_1951	COG4716	Myosin-crossreactive antigen
AVENP_1957	COG0454	-acetyltransferase
AVENP_1960	COG0519	Catalyzes the synthesis of GMP from XMP
AVENP_1960	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AVENP_1961	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AVENP_1962	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AVENP_1967	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AVENP_1968	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AVENP_1978	COG0642	Histidine kinase
AVENP_1981	COG3258	Cytochrome c
AVENP_1983	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AVENP_1985	COG0438	transferase activity, transferring glycosyl groups
AVENP_1986	COG0463	Glycosyl transferase, family 2
AVENP_1991	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AVENP_1992	COG1028	Short-chain dehydrogenase reductase Sdr
AVENP_1993	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AVENP_1995	COG2089	acid synthase
AVENP_1996	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AVENP_1998	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AVENP_2000	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
AVENP_2000	COG0662	Cupin 2, conserved barrel domain protein
AVENP_2003	COG0529	Catalyzes the synthesis of activated sulfate
AVENP_2013	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AVENP_2014	COG0300	oxidoreductase activity
AVENP_2015	COG1757	Na H antiporter
AVENP_2016	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AVENP_2017	COG0742	ribosomal rna small subunit methyltransferase
AVENP_2018	COG1418	mRNA catabolic process
AVENP_2020	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AVENP_2021	COG0552	protein localization to endoplasmic reticulum
AVENP_2030	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AVENP_2031	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AVENP_2033	COG1592	Rubrerythrin
AVENP_2034	COG1592	Rubrerythrin
AVENP_2036	COG0728	peptidoglycan biosynthetic process
AVENP_2037	COG1132	(ABC) transporter
AVENP_2038	COG0167	dihydroorotate dehydrogenase activity
AVENP_2041	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AVENP_2042	COG1028	Short-chain dehydrogenase reductase Sdr
AVENP_2043	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AVENP_2044	COG0750	zinc metalloprotease
AVENP_2045	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AVENP_2046	COG1942	4-Oxalocrotonate Tautomerase
AVENP_2048	COG0583	DNA-binding transcription factor activity
AVENP_2049	COG0134	indole-3-glycerol-phosphate synthase activity
AVENP_2051	COG0727	PFAM Uncharacterised protein family (UPF0153)
AVENP_2052	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AVENP_2054	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AVENP_2054	COG0674	pyruvate-flavodoxin oxidoreductase activity
AVENP_2055	COG1013	pyruvate-flavodoxin oxidoreductase activity
AVENP_2057	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AVENP_2058	COG2176	DNA-directed DNA polymerase activity
AVENP_2059	COG0135	phosphoribosylanthranilate isomerase activity
AVENP_2060	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AVENP_2064	COG0642	Histidine kinase
AVENP_2065	COG0745	RESPONSE REGULATOR receiver
AVENP_2067	COG0501	Belongs to the peptidase M48B family
AVENP_2068	COG1704	LemA family
AVENP_2069	COG1666	GTP binding
AVENP_2070	COG2233	PERMEase
AVENP_2071	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AVENP_2073	COG2363	Small membrane protein
AVENP_2075	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
AVENP_2084	COG0166	Belongs to the GPI family
AVENP_2087	COG0531	amino acid
AVENP_2088	COG4302	ethanolamine ammonia-lyase activity
AVENP_2089	COG4303	Ethanolamine ammonia lyase large subunit
AVENP_2092	COG0708	Exodeoxyribonuclease III
AVENP_2097	COG3706	GGDEF domain
AVENP_2109	COG4191	Histidine kinase
AVENP_2111	COG2200	EAL domain
AVENP_2111	COG3287	FIST C domain
AVENP_2111	COG2199	diguanylate cyclase activity
AVENP_2112	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AVENP_2115	COG0259	pyridoxamine-phosphate oxidase activity
AVENP_2117	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AVENP_2122	COG3287	FIST C domain
AVENP_2122	COG2199	diguanylate cyclase activity
AVENP_2122	COG2200	EAL domain
AVENP_2124	COG1984	allophanate hydrolase subunit 2
AVENP_2126	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AVENP_2129	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AVENP_2130	COG4753	response regulator
AVENP_2130	COG2207	Transcriptional regulator
AVENP_2137	COG0326	Molecular chaperone. Has ATPase activity
AVENP_2138	COG0840	transmembrane signaling receptor activity
AVENP_2140	COG0667	Aldo Keto reductase
AVENP_2141	COG1414	Transcriptional regulator
AVENP_2143	COG2050	protein possibly involved in aromatic compounds catabolism
AVENP_2145	COG1012	belongs to the aldehyde dehydrogenase family
AVENP_2146	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AVENP_2147	COG1024	Enoyl-CoA hydratase
AVENP_2157	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AVENP_2162	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AVENP_2166	COG2159	amidohydrolase
AVENP_2169	COG2828	Protein conserved in bacteria
AVENP_2172	COG0753	catalase activity
AVENP_2174	COG2995	paraquat-inducible protein a
AVENP_2177	COG5001	Diguanylate cyclase
AVENP_2177	COG5002	protein histidine kinase activity
AVENP_2181	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AVENP_2182	COG4335	DNA alkylation repair
AVENP_2185	COG3708	Transcriptional regulator
AVENP_2185	COG2207	Transcriptional regulator
AVENP_2186	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AVENP_2187	COG4773	Receptor
AVENP_2190	COG0010	Belongs to the arginase family
AVENP_2191	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AVENP_2192	COG2207	Transcriptional regulator
AVENP_2193	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AVENP_2199	COG1227	inorganic diphosphatase activity
AVENP_2203	COG1027	Aspartate ammonia-lyase
AVENP_2204	COG0745	RESPONSE REGULATOR receiver
AVENP_2206	COG1115	amino acid carrier protein
AVENP_2207	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AVENP_2208	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AVENP_2209	COG1047	Peptidyl-prolyl cis-trans
AVENP_2212	COG0823	Involved in the tonB-independent uptake of proteins
AVENP_2214	COG0848	biopolymer transport protein
AVENP_2215	COG0811	peptide transport
AVENP_2216	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AVENP_2217	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AVENP_2218	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AVENP_2219	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AVENP_2220	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AVENP_2221	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AVENP_2223	COG1475	DNA binding
AVENP_2224	COG1192	Involved in chromosome partitioning
AVENP_2225	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AVENP_2225	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AVENP_2228	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AVENP_2229	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AVENP_2230	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AVENP_2231	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AVENP_2232	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AVENP_2234	COG0358	DNA primase activity
AVENP_2236	COG0571	ribonuclease III activity
AVENP_2237	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AVENP_2238	COG1686	Belongs to the peptidase S11 family
AVENP_2239	COG0501	Belongs to the peptidase M48B family
AVENP_2243	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AVENP_2245	COG0706	membrane insertase activity
AVENP_2246	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AVENP_2247	COG0594	ribonuclease P activity
AVENP_2248	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AVENP_2249	COG0542	response to heat
AVENP_2250	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AVENP_2253	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AVENP_2254	COG1696	Membrane protein involved in D-alanine export
AVENP_2256	COG1696	Membrane protein involved in D-alanine export
AVENP_2258	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AVENP_2259	COG0745	RESPONSE REGULATOR receiver
AVENP_2260	COG3437	response regulator, receiver
AVENP_2262	COG0179	Fumarylacetoacetate (FAA) hydrolase
AVENP_2265	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AVENP_2268	COG0477	Major facilitator Superfamily
AVENP_2271	COG0138	bifunctional purine biosynthesis protein purh
AVENP_2272	COG0004	ammonium transporteR
AVENP_2273	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AVENP_2275	COG0739	heme binding
AVENP_2275	COG0741	lytic transglycosylase activity
AVENP_2275	COG1196	nuclear chromosome segregation
AVENP_2277	COG0456	acetyltransferase
AVENP_2278	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AVENP_2279	COG1917	Cupin 2, conserved barrel domain protein
AVENP_2281	COG0527	aspartate kinase activity
AVENP_2285	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AVENP_2287	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AVENP_2288	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AVENP_2302	COG0302	gtp cyclohydrolase
AVENP_2303	COG0598	Magnesium transport protein CorA
AVENP_2304	COG1459	type II secretion system
AVENP_2305	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AVENP_2308	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AVENP_2309	COG0606	chelatase, subunit chli
AVENP_2311	COG0242	peptide deformylase activity
AVENP_2312	COG0740	serine-type endopeptidase activity
AVENP_2313	COG0544	peptidyl-prolyl cis-trans isomerase activity
AVENP_2326	COG1064	alcohol dehydrogenase
AVENP_2327	COG2207	Transcriptional regulator
AVENP_2328	COG4681	YaeQ
AVENP_2330	COG0626	cystathionine gamma-synthase activity
AVENP_2332	COG0745	RESPONSE REGULATOR receiver
AVENP_2335	COG0840	transmembrane signaling receptor activity
AVENP_2336	COG2198	Histidine kinase
AVENP_2336	COG0643	Histidine kinase
AVENP_2341	COG0745	RESPONSE REGULATOR receiver
AVENP_2343	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
AVENP_2346	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AVENP_2347	COG2207	Transcriptional regulator
AVENP_2347	COG1917	Cupin 2, conserved barrel domain protein
AVENP_2350	COG1301	dicarboxylic acid transport
AVENP_2351	COG0840	transmembrane signaling receptor activity
AVENP_2354	COG1028	Short-chain dehydrogenase reductase Sdr
AVENP_2356	COG0840	transmembrane signaling receptor activity
AVENP_2358	COG2199	diguanylate cyclase activity
AVENP_2358	COG3287	FIST C domain
AVENP_2358	COG2200	EAL domain
AVENP_2359	COG0840	transmembrane signaling receptor activity
AVENP_2360	COG2200	EAL domain
AVENP_2361	COG2223	nitrite transmembrane transporter activity
AVENP_2362	COG2815	serine threonine protein kinase
AVENP_2362	COG0515	serine threonine protein kinase
AVENP_2363	COG3287	FIST C domain
AVENP_2363	COG2199	diguanylate cyclase activity
AVENP_2363	COG2200	EAL domain
AVENP_2364	COG0243	molybdopterin cofactor binding
AVENP_2366	COG3287	FIST C domain
AVENP_2366	COG2200	EAL domain
AVENP_2366	COG2199	diguanylate cyclase activity
AVENP_2367	COG0840	transmembrane signaling receptor activity
AVENP_2368	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AVENP_2369	COG4208	sulfate ABC transporter
AVENP_2370	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AVENP_2371	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AVENP_2372	COG1959	2 iron, 2 sulfur cluster binding
AVENP_2373	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AVENP_2378	COG1858	cytochrome C peroxidase
AVENP_2384	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AVENP_2385	COG0840	transmembrane signaling receptor activity
AVENP_2392	COG0668	transmembrane transport
AVENP_2398	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AVENP_2401	COG0348	domain, Protein
AVENP_2402	COG4191	Histidine kinase
AVENP_2403	COG4753	response regulator
AVENP_2403	COG2207	Transcriptional regulator
AVENP_2406	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AVENP_2411	COG0716	FMN binding
AVENP_2414	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AVENP_2422	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AVENP_2423	COG2201	protein-glutamate methylesterase activity
AVENP_2426	COG3437	response regulator, receiver
AVENP_2426	COG0784	Response regulator, receiver
AVENP_2427	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AVENP_2433	COG0731	radical SAM domain protein
AVENP_2434	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AVENP_2436	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AVENP_2439	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AVENP_2441	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AVENP_2444	COG0438	transferase activity, transferring glycosyl groups
AVENP_2449	COG0726	polysaccharide deacetylase
AVENP_2452	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AVENP_2456	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AVENP_2457	COG0483	inositol monophosphate 1-phosphatase activity
AVENP_2458	COG0493	'glutamate synthase
AVENP_2459	COG0070	glutamate synthase
AVENP_2459	COG0069	glutamate synthase activity
AVENP_2459	COG0067	glutamate synthase
AVENP_2462	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AVENP_2463	COG0584	glycerophosphoryl diester phosphodiesterase
AVENP_2465	COG0745	RESPONSE REGULATOR receiver
AVENP_2469	COG0840	transmembrane signaling receptor activity
AVENP_2472	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AVENP_2472	COG2205	protein histidine kinase activity
AVENP_2483	COG0284	orotidine-5'-phosphate decarboxylase activity
AVENP_2484	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AVENP_2485	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AVENP_2486	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AVENP_2491	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AVENP_2496	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AVENP_2497	COG1450	Type ii and iii secretion system protein
AVENP_2508	COG1739	Uncharacterized protein family UPF0029
AVENP_2510	COG0196	riboflavin kinase activity
AVENP_2511	COG2226	methyltransferase
AVENP_2512	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AVENP_2514	COG0277	FAD linked oxidase domain protein
AVENP_2526	COG0542	response to heat
AVENP_2527	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AVENP_2528	COG0714	Associated with various cellular activities
AVENP_2531	COG2304	oxidoreductase activity
AVENP_2535	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AVENP_2537	COG0318	PFAM AMP-dependent synthetase and ligase
AVENP_2538	COG2030	dehydratase
AVENP_2542	COG0840	transmembrane signaling receptor activity
AVENP_2543	COG1970	mechanosensitive ion channel activity
AVENP_2544	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AVENP_2549	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AVENP_2550	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AVENP_2551	COG1157	protein secretion by the type III secretion system
AVENP_2553	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AVENP_2557	COG1677	Flagellar hook-basal body complex protein FliE
AVENP_2559	COG0455	bacterial-type flagellum organization
AVENP_2560	COG1419	protein localization to endoplasmic reticulum
AVENP_2565	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AVENP_2570	COG1749	Flagellar hook protein flgE
AVENP_2573	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AVENP_2575	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AVENP_2576	COG1766	The M ring may be actively involved in energy transduction
AVENP_2577	COG1815	bacterial-type flagellum-dependent cell motility
AVENP_2578	COG4786	Flagellar basal body rod
AVENP_2580	COG0745	RESPONSE REGULATOR receiver
AVENP_2584	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AVENP_2585	COG1837	Belongs to the UPF0109 family
AVENP_2586	COG0228	four-way junction DNA binding
AVENP_2587	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AVENP_2588	COG0564	pseudouridine synthase activity
AVENP_2589	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AVENP_2589	COG1519	Transferase
AVENP_2591	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AVENP_2592	COG0752	glycyl-tRNA synthetase alpha subunit
AVENP_2594	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AVENP_2597	COG0840	transmembrane signaling receptor activity
AVENP_2598	COG0497	DNA recombination
AVENP_2599	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AVENP_2600	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AVENP_2601	COG0049	tRNA binding
AVENP_2602	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AVENP_2603	COG2814	Major facilitator Superfamily
AVENP_2604	COG2267	carboxylic ester hydrolase activity
AVENP_2607	COG4895	conserved protein (DUF2196)
AVENP_2609	COG0840	transmembrane signaling receptor activity
AVENP_2613	COG0450	alkyl hydroperoxide reductase
AVENP_2614	COG3118	belongs to the thioredoxin family
AVENP_2637	COG0582	viral genome integration into host DNA
AVENP_2640	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AVENP_2641	COG0085	RNA polymerase activity
AVENP_2642	COG0222	ribosome binding
AVENP_2643	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AVENP_2644	COG0081	regulation of translation
AVENP_2645	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AVENP_2646	COG0250	Participates in transcription elongation, termination and antitermination
AVENP_2649	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AVENP_2650	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AVENP_2656	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AVENP_2657	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AVENP_2658	COG0444	Belongs to the ABC transporter superfamily
AVENP_2659	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AVENP_2660	COG0174	glutamine synthetase
AVENP_2662	COG0314	molybdopterin synthase activity
AVENP_2664	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
AVENP_2665	COG1968	undecaprenyl-diphosphatase activity
AVENP_2667	COG0772	Belongs to the SEDS family
AVENP_2668	COG0768	penicillin binding
AVENP_2669	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AVENP_2680	COG0512	Glutamine amidotransferase of anthranilate synthase
AVENP_2681	COG1840	ABC-type Fe3 transport system, periplasmic component
AVENP_2682	COG1178	ABC-type Fe3 transport system permease component
AVENP_2683	COG3842	ATPase activity
AVENP_2684	COG3706	GGDEF domain
AVENP_2691	COG2183	response to ionizing radiation
AVENP_2693	COG2199	diguanylate cyclase activity
AVENP_2693	COG3287	FIST C domain
AVENP_2693	COG2200	EAL domain
AVENP_2694	COG0251	oxidation-reduction process
AVENP_2697	COG2095	MarC family integral membrane protein
AVENP_2698	COG0765	amino acid transport
AVENP_2704	COG0840	transmembrane signaling receptor activity
AVENP_2706	COG1012	belongs to the aldehyde dehydrogenase family
AVENP_2707	COG0410	ABC transporter
AVENP_2716	COG0586	Pfam SNARE associated Golgi protein
AVENP_2718	COG0335	large ribosomal subunit rRNA binding
AVENP_2719	COG0336	Belongs to the RNA methyltransferase TrmD family
AVENP_2721	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AVENP_2722	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AVENP_2723	COG0356	it plays a direct role in the translocation of protons across the membrane
AVENP_2725	COG1074	ATP-dependent DNA helicase activity
AVENP_2726	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AVENP_2727	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AVENP_2728	COG0723	plastoquinol--plastocyanin reductase activity
AVENP_2729	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AVENP_2732	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AVENP_2734	COG0303	'Molybdopterin
AVENP_2735	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AVENP_2737	COG0602	queuosine metabolic process
AVENP_2739	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AVENP_2741	COG0825	malonyl-CoA metabolic process
AVENP_2742	COG0537	adenosine 5'-monophosphoramidase activity
AVENP_2743	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AVENP_2744	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AVENP_2744	COG0072	phenylalanine-tRNA ligase activity
AVENP_2745	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AVENP_2746	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AVENP_2747	COG0539	negative regulation of cytoplasmic translation
AVENP_2747	COG1185	polyribonucleotide nucleotidyltransferase activity
AVENP_2748	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AVENP_2749	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AVENP_2750	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AVENP_2750	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AVENP_2751	COG0779	Required for maturation of 30S ribosomal subunits
AVENP_2752	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AVENP_2753	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AVENP_2755	COG0083	homoserine kinase activity
AVENP_2757	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AVENP_2760	COG0157	Belongs to the NadC ModD family
AVENP_2762	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AVENP_2764	COG4773	Receptor
AVENP_2766	COG4773	Receptor
AVENP_2767	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AVENP_2770	COG1289	transmembrane transporter activity
AVENP_2780	COG3278	Belongs to the heme-copper respiratory oxidase family
AVENP_2781	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AVENP_2782	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AVENP_2783	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AVENP_2784	COG0210	DNA helicase
AVENP_2786	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AVENP_2786	COG3153	acetyltransferase
AVENP_2787	COG1242	4 iron, 4 sulfur cluster binding
AVENP_2788	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AVENP_2789	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AVENP_2790	COG0492	ferredoxin-NADP+ reductase activity
AVENP_2791	COG3118	belongs to the thioredoxin family
AVENP_2792	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AVENP_2796	COG0791	NLP P60 protein
AVENP_2797	COG0791	NLP P60 protein
AVENP_2802	COG0424	maF-like protein
AVENP_2804	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AVENP_2805	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AVENP_2806	COG0077	Prephenate dehydratase
AVENP_2806	COG1605	Chorismate mutase
AVENP_2807	COG0019	diaminopimelate decarboxylase activity
AVENP_2808	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AVENP_2809	COG0149	triose-phosphate isomerase activity
AVENP_2810	COG0126	phosphoglycerate kinase activity
AVENP_2812	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AVENP_2814	COG0018	arginyl-trna synthetase
AVENP_2815	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AVENP_2816	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AVENP_2817	COG0204	Acyl-transferase
AVENP_2819	COG0047	phosphoribosylformylglycinamidine synthase activity
AVENP_2820	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AVENP_2821	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AVENP_2822	COG0793	Belongs to the peptidase S41A family
AVENP_2825	COG0585	pseudouridine synthase activity
AVENP_2826	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AVENP_2828	COG1136	(ABC) transporter
AVENP_2828	COG0577	efflux transmembrane transporter activity
AVENP_2849	COG0129	dihydroxy-acid dehydratase activity
AVENP_2851	COG0745	RESPONSE REGULATOR receiver
AVENP_2852	COG0642	Histidine kinase
AVENP_2855	COG0702	epimerase
AVENP_2858	COG1492	cobalamin metabolic process
AVENP_2859	COG2205	protein histidine kinase activity
AVENP_2863	COG4771	TonB-dependent receptor
AVENP_2865	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AVENP_2868	COG2095	MarC family integral membrane protein
AVENP_2869	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AVENP_2870	COG0745	RESPONSE REGULATOR receiver
AVENP_2871	COG5002	protein histidine kinase activity
AVENP_2873	COG0745	RESPONSE REGULATOR receiver
AVENP_2875	COG0252	asparaginase activity
AVENP_2876	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AVENP_2877	COG1027	Aspartate ammonia-lyase
AVENP_2879	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AVENP_2880	COG1053	succinate dehydrogenase
AVENP_2882	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
AVENP_2883	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
AVENP_2884	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
AVENP_2885	COG3287	FIST C domain
AVENP_2885	COG2199	diguanylate cyclase activity
AVENP_2885	COG2200	EAL domain
AVENP_2887	COG4232	protein-disulfide reductase activity
AVENP_2888	COG3118	belongs to the thioredoxin family
AVENP_2891	COG0189	ligase activity
AVENP_2894	COG2199	diguanylate cyclase activity
AVENP_2894	COG2200	EAL domain
AVENP_2894	COG3287	FIST C domain
AVENP_2899	COG0443	Heat shock 70 kDa protein
AVENP_2900	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AVENP_2901	COG1420	regulation of RNA biosynthetic process
AVENP_2904	COG2197	response regulator
AVENP_2906	COG0101	tRNA pseudouridine synthase activity
AVENP_2908	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AVENP_2909	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AVENP_2910	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AVENP_2911	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AVENP_2913	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AVENP_2914	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AVENP_2923	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AVENP_2927	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AVENP_2928	COG2226	methyltransferase
AVENP_2931	COG1216	Glycosyl transferase, family 2
AVENP_2935	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AVENP_2938	COG1028	Short-chain dehydrogenase reductase Sdr
AVENP_2940	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AVENP_2941	COG3980	spore coat polysaccharide biosynthesis protein
AVENP_2942	COG2089	acid synthase
AVENP_2943	COG1083	cytidylyl-transferase
AVENP_2944	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AVENP_2945	COG1086	Polysaccharide biosynthesis protein
AVENP_2947	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AVENP_2948	COG0148	phosphopyruvate hydratase activity
AVENP_2951	COG0475	glutathione-regulated potassium exporter activity
AVENP_2951	COG0569	domain protein
AVENP_2952	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AVENP_2955	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AVENP_2956	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
AVENP_2958	COG1007	ATP synthesis coupled electron transport
AVENP_2960	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AVENP_2961	COG0713	ATP synthesis coupled electron transport
AVENP_2962	COG0839	Belongs to the complex I subunit 6 family
AVENP_2963	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AVENP_2964	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AVENP_2968	COG0649	NAD binding
AVENP_2969	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AVENP_2970	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AVENP_2971	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AVENP_2972	COG1222	aaa ATPase
AVENP_2978	COG0659	secondary active sulfate transmembrane transporter activity
AVENP_2981	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AVENP_2982	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AVENP_2984	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
AVENP_2985	COG1252	NADH dehydrogenase
AVENP_2986	COG2200	EAL domain
AVENP_2986	COG3287	FIST C domain
AVENP_2986	COG2199	diguanylate cyclase activity
AVENP_2987	COG0733	neurotransmitter:sodium symporter activity
AVENP_2989	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AVENP_2991	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AVENP_2992	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AVENP_2993	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AVENP_2997	COG0445	tRNA wobble uridine modification
AVENP_2999	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AVENP_2999	COG3608	succinylglutamate desuccinylase aspartoacylase
AVENP_3000	COG2010	Cytochrome c
AVENP_3000	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AVENP_3004	COG0348	domain, Protein
AVENP_3005	COG0504	CTP synthase activity
AVENP_3006	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AVENP_3006	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AVENP_3012	COG0587	DNA-directed DNA polymerase activity
AVENP_3013	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AVENP_3016	COG0315	cyclic pyranopterin monophosphate synthase activity
AVENP_3017	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AVENP_3020	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
AVENP_3021	COG0159	tryptophan synthase activity
AVENP_3022	COG0038	chloride channel
AVENP_3023	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AVENP_3024	COG2255	four-way junction helicase activity
AVENP_3025	COG0628	permease
AVENP_3027	COG4628	conserved protein (DUF2132)
AVENP_3040	COG0670	Belongs to the BI1 family
AVENP_3042	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AVENP_3044	COG0233	cytoplasmic translational termination
AVENP_3045	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AVENP_3047	COG2814	Major facilitator Superfamily
AVENP_3048	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
AVENP_3048	COG3264	Mechanosensitive ion channel
AVENP_3051	COG3022	response to hydroperoxide
AVENP_3052	COG3012	SEC-C Motif Domain Protein
AVENP_3067	COG3210	domain, Protein
AVENP_3067	COG3210	domain, Protein
AVENP_3068	COG2831	hemolysin activation secretion protein
AVENP_3069	COG0848	biopolymer transport protein
AVENP_3070	COG0811	peptide transport
AVENP_3074	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AVENP_3075	COG1012	belongs to the aldehyde dehydrogenase family
AVENP_3076	COG0589	response to stress
AVENP_3079	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AVENP_3080	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AVENP_3083	COG0745	RESPONSE REGULATOR receiver
AVENP_3084	COG1012	belongs to the aldehyde dehydrogenase family
AVENP_3085	COG0028	Belongs to the TPP enzyme family
AVENP_3086	COG1704	LemA family
AVENP_3089	COG0546	phosphoglycolate phosphatase activity
AVENP_3092	COG2814	Major facilitator Superfamily
AVENP_3095	COG0840	transmembrane signaling receptor activity
AVENP_3096	COG0784	Response regulator, receiver
AVENP_3096	COG3437	response regulator, receiver
AVENP_3104	COG2081	HI0933 family
AVENP_3107	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AVENP_3114	COG1959	2 iron, 2 sulfur cluster binding
AVENP_3117	COG0175	sulfate reduction
AVENP_3118	COG0175	sulfate reduction
AVENP_3119	COG2895	sulfate adenylyltransferase (ATP) activity
AVENP_3120	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AVENP_3121	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AVENP_3122	COG1408	metallophosphoesterase
AVENP_3125	COG2308	Evidence 4 Homologs of previously reported genes of
AVENP_3127	COG0840	transmembrane signaling receptor activity
AVENP_3131	COG2308	Evidence 4 Homologs of previously reported genes of
AVENP_3135	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AVENP_3140	COG0745	RESPONSE REGULATOR receiver
AVENP_3141	COG0642	Histidine kinase
AVENP_3142	COG3721	Heme iron utilization protein
AVENP_3143	COG1132	(ABC) transporter
AVENP_3145	COG0748	coenzyme F420 binding
AVENP_3146	COG4558	Periplasmic binding protein
AVENP_3147	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AVENP_3148	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AVENP_3149	COG4771	TonB-dependent receptor
AVENP_3151	COG2226	methyltransferase
AVENP_3152	COG3437	response regulator, receiver
AVENP_3152	COG0784	Response regulator, receiver
AVENP_3153	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
AVENP_3154	COG2066	Belongs to the glutaminase family
AVENP_3155	COG2860	membrane
AVENP_3157	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AVENP_3158	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group