locus-tag	class	description
c1A100	ENOG4107U7N	hydantoinase B oxoprolinase
c1A102	ENOG4107RID	5-oxoprolinase (ATP-hydrolyzing)
c1A105	ENOG4107SZ9	Hydantoinase oxoprolinase
c1A18	ENOG4107QPN	acyl-Coa dehydrogenase
c1A200	ENOG4105RQI	acetone carboxylase gamma subunit
c1A203	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
c1A206	ENOG4105NAU	thioesterase Superfamily protein
c1A208	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
c1A212	ENOG4105CHU	acetyl-coa acetyltransferase
c1A232	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
c1A234	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
c1A237	ENOG4105D07	Signal peptide peptidase, SppA
c1A25	ENOG4105DSJ	YicC domain protein
c1A283	ENOG4105KPY	Small multidrug resistance protein
c1A39	ENOG4105CSA	Coproporphyrinogen iii oxidase
c1A43	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
c1A46	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
c1A49	ENOG4105DFP	Integrase
c1A53	ENOG4106NZI	LysR family Transcriptional regulator
c1A56	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
c1A57	ENOG4105CKI	cobalamin synthesis protein
c1A58	ENOG4108KEZ	Dehydrogenase
c1A74	ENOG4105F2I	Transposase
c1A75	ENOG4105BZU	Histidine kinase
c1A77	ENOG4105WH1	Two component transcriptional regulator luxr family
c1A84	ENOG4107QVI	Methyltransferase, type 11
c1A95	ENOG4105DZS	Phenylacetate-CoA ligase
c2A172	ENOG4105CHU	acetyl-coa acetyltransferase
c2A173	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
c2A174	ENOG4105E39	Enoyl-CoA hydratase
c2A178	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
c2A195	ENOG4105C2C	drug resistance transporter, Bcr CflA
c2A227	ENOG4105F5W	AtP-binding protein
c2A313	ENOG4105CHR	reductase
c2A314	ENOG4105CHR	reductase
ebA1002	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
ebA1012	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
ebA1017	ENOG4108J2R	molybdopterin oxidoreductase
ebA1021	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
ebA1022	ENOG4108WBT	adenosyltransferase
ebA1024	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
ebA1026	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
ebA1027	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
ebA1030	ENOG4105N42	UPF0307 protein
ebA1031	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
ebA1032	ENOG4105CH5	extracellular solute-binding protein, family 7
ebA1033	ENOG4105CH5	extracellular solute-binding protein, family 7
ebA1037	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
ebA1042	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
ebA1044	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
ebA1045	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
ebA1046	ENOG4105D06	uba thif-type nad fad binding protein
ebA1050	ENOG4105CN1	protease
ebA1052	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
ebA1054	ENOG4105VW4	glutaredoxin 3
ebA1056	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
ebA1060	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
ebA1065	ENOG4105MJ2	Competence protein
ebA1066	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
ebA1067	ENOG4106T9E	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
ebA1071	ENOG4105D52	delta-aminolevulinic acid dehydratase
ebA1073	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
ebA1075	ENOG4106RE7	Cytochrome
ebA1078	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
ebA1080	ENOG4105E66	phosphoriboisomerase A
ebA1083	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
ebA1086	ENOG4105BZU	Histidine kinase
ebA1090	ENOG4108EKC	n-acetylglutamate synthase
ebA1094	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
ebA1099	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
ebA110	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
ebA1101	ENOG4105CV1	Transketolase (EC 2.2.1.1)
ebA1102	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
ebA1103	ENOG4105BZA	Phosphoglycerate kinase
ebA1105	ENOG4105CA9	Pyruvate kinase
ebA1121	ENOG4108ZG0	Ompa motb domain protein
ebA1125	ENOG4105C8V	SAICAR synthetase
ebA1131	ENOG4105DGW	oligopeptidase A
ebA1138	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
ebA1139	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
ebA114	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
ebA1140	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
ebA1141	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
ebA1142	ENOG4105EHM	Aminoglycoside phosphotransferase
ebA1143	ENOG4108S0S	Nucleotidyl transferase
ebA1146	ENOG4107RAQ	aminopeptidase
ebA1148	ENOG4105D0A	hydroxylase
ebA1152	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
ebA1153	ENOG4105DC1	bifunctional purine biosynthesis protein purh
ebA1155	ENOG4105C12	Phosphoribosylglycinamide synthetase
ebA1156	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
ebA116	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
ebA1162	ENOG4105ECF	c-methyltransferase
ebA1165	ENOG41076E6	Uroporphyrinogen-III Synthase
ebA1166	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
ebA1167	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
ebA1169	ENOG4108NEV	two component transcriptional regulator, LytTR family
ebA1170	ENOG4105CH7	arginosuccinase
ebA1177	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
ebA1179	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
ebA118	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
ebA1181	ENOG4105DHQ	Histidine kinase
ebA1182	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
ebA1185	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
ebA1191	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
ebA1192	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
ebA1194	ENOG4105KB2	stringent starvation protein b
ebA1195	ENOG4107MKT	Stringent starvation protein a
ebA1196	ENOG4105EIX	cytochrome c1
ebA1197	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
ebA1198	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
ebA1200	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
ebA1202	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
ebA1203	ENOG4107QMP	dna polymerase iii subunits gamma and tau
ebA1206	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
ebA1216	ENOG4108IFG	nitrite reductase, (NAD(P)H)
ebA1223	ENOG4108VAU	general secretion pathway protein G
ebA1225	ENOG4105D7Q	type ii secretion system
ebA1226	ENOG4107QHF	type ii secretion system protein e
ebA1246	ENOG4105C2N	RNA methyltransferase TrmH family group 3
ebA1247	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
ebA1249	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
ebA125	ENOG4108ZXC	Two component transcriptional regulator, luxr family
ebA1250	ENOG4105C49	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
ebA1252	ENOG4105EPW	hflc protein
ebA1253	ENOG4107QJR	hflk protein
ebA1254	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
ebA1255	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
ebA1256	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
ebA1258	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
ebA1259	ENOG4105N21	Membrane
ebA126	ENOG4105BZU	Histidine kinase
ebA1260	ENOG4105CUT	histidyl-tRNA synthetase
ebA1261	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
ebA1268	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
ebA1271	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
ebA1272	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
ebA1283	ENOG4105C0H	protease
ebA1284	ENOG4107QNR	UPF0135 protein
ebA1285	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
ebA1289	ENOG4105K59	histidine triad (HIT) protein
ebA1290	ENOG4105KPZ	phosphoribosyl-atp pyrophosphatase
ebA1291	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
ebA1293	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
ebA1295	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
ebA1296	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
ebA1297	ENOG4105CIH	Imidazole acetol-phosphate transaminase
ebA1299	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
ebA1300	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
ebA1302	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
ebA1304	ENOG4105E3A	(ABC) transporter
ebA1306	ENOG4105DA5	(ABC) transporter
ebA1310	ENOG410903C	(LipO)protein
ebA1311	ENOG4107PE3	Mammalian cell entry related domain protein
ebA1312	ENOG4105CY3	ABC transporter, permease
ebA1313	ENOG4105DHJ	ABC, transporter
ebA1315	ENOG4105C2X	Arabinose 5-phosphate isomerase
ebA1316	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
ebA1320	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
ebA1321	ENOG4105E39	Enoyl-CoA hydratase
ebA1324	ENOG4105CZX	twitching motility protein
ebA1327	ENOG4105E9Q	Acyl-transferase
ebA1328	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
ebA133	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
ebA1330	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
ebA1331	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
ebA1334	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
ebA1335	ENOG4108JU5	Magnesium and cobalt efflux protein
ebA1336	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
ebA1337	ENOG4105C9A	Phoh family
ebA1339	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
ebA135	ENOG4107QSN	dihydrolipoamide acetyltransferase
ebA1353	ENOG4105F5W	AtP-binding protein
ebA136	ENOG4107QN2	dihydrolipoyl dehydrogenase
ebA1360	ENOG4105DFP	Integrase
ebA1378	ENOG4105MSY	salicylate hydroxylase
ebA1383	ENOG4105CBP	Major Facilitator
ebA1387	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
ebA1390	ENOG4105CAK	Cell division ATP-binding protein ftsE
ebA1396	ENOG4106H78	methyltransferase
ebA1397	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
ebA1400	ENOG410890F	Dynamin family
ebA1401	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
ebA1403	ENOG4105DJQ	tetratricopeptide tpr_2 repeat protein
ebA1404	ENOG41081V9	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
ebA1405	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
ebA1406	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
ebA1409	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
ebA1411	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
ebA1413	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
ebA1415	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
ebA1417	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
ebA1418	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
ebA1420	ENOG4107QTF	adenylosuccinate lyase
ebA1421	ENOG4105NWN	ApaG protein
ebA1422	ENOG4105BZU	Histidine kinase
ebA1430	ENOG4105DFP	Integrase
ebA1431	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
ebA1433	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
ebA1436	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
ebA1438	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
ebA1439	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
ebA1442	ENOG4105CPF	Cell wall formation (By similarity)
ebA1443	ENOG4105DFU	Cell wall formation (By similarity)
ebA1444	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
ebA1445	ENOG4105CNI	cell division protein FtsW
ebA1447	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
ebA1448	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
ebA1449	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
ebA145	ENOG4108RAV	Conserved protein
ebA1450	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
ebA1451	ENOG4105CJN	penicillin-binding protein
ebA1452	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
ebA1456	ENOG4105EKE	dihydroorotase
ebA1457	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
ebA1463	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
ebA1464	ENOG4105W4M	Transport-associated protein
ebA1466	ENOG4105DFU	Cell wall formation (By similarity)
ebA1468	ENOG4107QX9	Thiol disulfide interChange protein
ebA1471	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
ebA1472	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
ebA1474	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
ebA1475	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
ebA1477	ENOG41080IJ	Diacylglycerol kinase
ebA148	ENOG4108UVJ	appr-1-p processing domain protein
ebA1488	ENOG4105K59	histidine triad (HIT) protein
ebA1516	ENOG4105CPK	Glycosyl transferase (Group 1
ebA1518	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
ebA1519	ENOG4105EXC	Acyl-transferase
ebA152	ENOG4105DMT	epimerase dehydratase
ebA1520	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
ebA1527	ENOG4105CPK	Glycosyl transferase (Group 1
ebA1531	ENOG4105D3Q	Sugar transferase
ebA1532	ENOG41080C8	DUF218 domain
ebA1535	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
ebA1543	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
ebA1544	ENOG4105E5H	Transposase
ebA156	ENOG4105BZ9	Cytochrome C oxidase, subunit I
ebA1561	ENOG4105VDM	plasmid maintenance system antidote protein, xre family
ebA158	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
ebA1593	ENOG4105EY8	ABC transporter
ebA1594	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
ebA1602	ENOG4105GVR	general secretion pathway protein D
ebA1619	ENOG4105D7Q	type ii secretion system
ebA1622	ENOG4107QHF	type ii secretion system protein e
ebA1627	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
ebA163	ENOG4105BZU	Histidine kinase
ebA1631	ENOG4105ESV	Glycosyl transferase, family 4
ebA1636	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
ebA1642	ENOG4105DFG	type I secretion outer membrane protein
ebA1645	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
ebA165	ENOG4107QN1	sodium solute
ebA166	ENOG4108IRC	dna polymerase iii
ebA1664	ENOG4108JUA	Transcriptional regulator
ebA1670	ENOG41085KW	ppic-type peptidyL-prolyl cis-trans isomerase
ebA1679	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
ebA168	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
ebA1682	ENOG4108ESY	Metal dependent phosphohydrolase
ebA1688	ENOG4105E6M	Sulphatase-modifying factor protein
ebA169	ENOG4105BZU	Histidine kinase
ebA1702	ENOG4108RVZ	hydrogenase
ebA1712	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
ebA172	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
ebA1722	ENOG4105KRS	Proteinase inhibitor
ebA1726	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
ebA1728	ENOG4105IPS	esterase
ebA1729	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
ebA1735	ENOG4105E2X	shikimate dehydrogenase
ebA1739	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
ebA1741	ENOG4105CJW	magnesium transporter
ebA1743	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
ebA1745	ENOG4105DWF	phosphomethylpyrimidine kinase
ebA1750	ENOG4105C8Q	Methyl-accepting chemotaxis
ebA1751	ENOG4105CBS	Chea signal transduction histidine kinase
ebA1753	ENOG4108UJU	UPF0301 protein
ebA1756	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
ebA1757	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
ebA1759	ENOG4105CXT	aspartate transcarbamylase
ebA1760	ENOG4105CD3	dihydroorotase
ebA1762	ENOG4105VZ9	UPF0235 protein
ebA1764	ENOG4108VIA	integral membrane protein
ebA1766	ENOG4105II7	pyrroline-5-carboxylate reductase
ebA1768	ENOG4105DFA	alanine racemase domain protein
ebA1770	ENOG4105CZX	twitching motility protein
ebA1772	ENOG4105CZX	twitching motility protein
ebA1773	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
ebA1774	ENOG4108YXA	Membrane
ebA1782	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
ebA1787	ENOG4105BZU	Histidine kinase
ebA1803	ENOG4105BZU	Histidine kinase
ebA1807	ENOG4108JJA	ABC, transporter
ebA1809	ENOG4105MYN	Zinc uptake regulation protein
ebA1812	ENOG4105DIK	(ABC) transporter
ebA1813	ENOG4105CC5	ABC transporter
ebA1814	ENOG4105DSE	periplasmic solute binding protein
ebA1817	ENOG4105HF0	Membrane
ebA1822	ENOG4105C01	Dihydroxy-acid dehydratase
ebA1823	ENOG4108YXG	UPF0502 protein
ebA1825	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
ebA183	ENOG4105GMT	ATPase associated with various cellular activities aaa_5
ebA1830	ENOG4105BZU	Histidine kinase
ebA1837	ENOG4108UQY	Iron-storage protein
ebA1846	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
ebA1847	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
ebA1848	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
ebA1866	ENOG4107SJW	iron permease, FTR1
ebA1871	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
ebA1874	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
ebA1875	ENOG4105SYT	Methylenetetrahydrofolate reductase
ebA188	ENOG4105FAE	von Willebrand factor, type A
ebA1881	ENOG4105D7A	ATP-binding protein
ebA189	ENOG4105VP2	Transcriptional regulator, Crp Fnr family
ebA192	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
ebA1932	ENOG4105D25	secreted protein
ebA1953	ENOG4105C1G	acyl-Coa dehydrogenase
ebA1954	ENOG4108IPT	Naphthoate synthase
ebA1957	ENOG4108SY4	MarR family Transcriptional regulator
ebA1959	ENOG4105C1G	acyl-Coa dehydrogenase
ebA1960	ENOG4105CEY	Amp-dependent synthetase and ligase
ebA1961	ENOG4105E39	Enoyl-CoA hydratase
ebA1969	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
ebA1971	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
ebA1972	ENOG4105BZS	acriflavin resistance protein
ebA1973	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
ebA1979	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
ebA1980	ENOG4105CFG	Acts as a chaperone (By similarity)
ebA1985	ENOG4105CSU	acyl-Coa dehydrogenase
ebA1986	ENOG4105C3M	thioredoxin reductase
ebA199	ENOG4105F5W	AtP-binding protein
ebA2009	ENOG4105F5W	AtP-binding protein
ebA2016	ENOG4105D58	Diguanylate phosphodiesterase
ebA2022	ENOG4105E09	nadh pyrophosphatase
ebA2023	ENOG4105GR3	Histidine kinase
ebA2026	ENOG41061ZR	Transcriptional regulator
ebA2038	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
ebA204	ENOG4106IJN	integrase catalytic domain-containing protein
ebA2046	ENOG4108RZE	Tetr family transcriptional regulator
ebA2047	ENOG4105DRR	Transcriptional regulator, GntR family
ebA2055	ENOG4105C1G	acyl-Coa dehydrogenase
ebA2066	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
ebA208	ENOG4105F5W	AtP-binding protein
ebA2087	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
ebA2089	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
ebA2097	ENOG4105KME	endoribonuclease L-psp
ebA2099	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
ebA2102	ENOG4105CH6	catalase
ebA2111	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
ebA2113	ENOG4108ETV	ABC transporter
ebA2117	ENOG4107ENK	receptor
ebA2123	ENOG4105F5W	AtP-binding protein
ebA2133	ENOG4105EFT	decarboxylase
ebA2136	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
ebA2143	ENOG4108Z9W	Outer membrane porin
ebA2146	ENOG4105BZU	Histidine kinase
ebA2147	ENOG4105BZU	Histidine kinase
ebA2148	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
ebA2152	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
ebA2168	ENOG4105EP1	Efflux transporter rnd family, mfp subunit
ebA2176	ENOG4108IJF	Heavy metal efflux pump, CzcA
ebA2183	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
ebA2186	ENOG4107RUY	(E1 component), alpha subunit
ebA2188	ENOG4107QSN	dihydrolipoamide acetyltransferase
ebA2191	ENOG4105E39	Enoyl-CoA hydratase
ebA2194	ENOG4105CD5	CoA-binding domain protein
ebA220	ENOG41067CV	Integrase
ebA2202	ENOG4107R11	Transcriptional regulator
ebA222	ENOG4107YZX	Universal stress protein
ebA2222	ENOG4105DA4	cytochrome c-type biogenesis protein
ebA2233	ENOG4105C4X	radical SAM domain protein
ebA2241	ENOG4105CFP	Peptidase U32
ebA2242	ENOG4105C26	Dehydrogenase
ebA2244	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
ebA2245	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
ebA2248	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
ebA2254	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
ebA2256	ENOG4105D49	3-dehydroquinate synthase
ebA2258	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
ebA2259	ENOG4105E4G	Type IV pilus
ebA2268	ENOG4108JQC	penicillin-binding protein 1A
ebA2271	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
ebA2275	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
ebA2278	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
ebA2286	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
ebA2293	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
ebA2294	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
ebA2295	ENOG4105RUM	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
ebA2297	ENOG4105CB5	ATP-dependent DNA helicase recG
ebA2303	ENOG4105CS1	NAD(P)H quinone oxidoreductase
ebA2304	ENOG4105EUB	pirin domain protein
ebA2313	ENOG4105E39	Enoyl-CoA hydratase
ebA2314	ENOG4105CHU	acetyl-coa acetyltransferase
ebA232	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
ebA234	ENOG4105FF2	Type I DHQase
ebA240	ENOG4105BZU	Histidine kinase
ebA2402	ENOG4105W5Q	DNA repair protein (RadC
ebA2413	ENOG4105C0D	helicase
ebA2416	ENOG4107QMH	DNA methylase
ebA2443	ENOG4105D06	uba thif-type nad fad binding protein
ebA2458	ENOG4108IYH	Dna topoisomerase
ebA2469	ENOG4107QJE	Chromosome Partitioning Protein
ebA2481	ENOG4105DFP	Integrase
ebA2484	ENOG4105F5W	AtP-binding protein
ebA2486	ENOG4105DFP	Integrase
ebA2514	ENOG4105W5Q	DNA repair protein (RadC
ebA2528	ENOG4108RU0	short-chain dehydrogenase reductase
ebA2533	ENOG4105C5H	ABC transporter
ebA2535	ENOG4105D7V	transposase
ebA2542	ENOG4107RT3	EamA-like transporter family
ebA2545	ENOG41081YB	ApbE family
ebA2546	ENOG4105D7Z	glutathione synthase
ebA2549	ENOG4105XEZ	This methylase recognizes the double-stranded sequence TCGA, causes specific methylation on A-4 on both strands and protects the DNA from cleavage by the
ebA2575	ENOG4105DGN	Electron transport complex
ebA2576	ENOG4108R3D	Electron transport complex
ebA2578	ENOG4105D6A	Electron transport complex
ebA2579	ENOG4107QTR	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
ebA2585	ENOG4108E8M	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
ebA2586	ENOG4105VDB	UPF0125 protein
ebA2590	ENOG4105EXU	Membrane
ebA2596	ENOG4105BZU	Histidine kinase
ebA2601	ENOG4108JJ7	ABC transporter
ebA2612	ENOG4105DZR	Type I site-specific deoxyribonuclease
ebA2615	ENOG4107R11	Transcriptional regulator
ebA2617	ENOG4107TSN	permease
ebA2625	ENOG4105C11	sulfate adenylyltransferase), subunit 2
ebA2628	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
ebA2630	ENOG4105EA8	2-Nitropropane dioxygenase
ebA2633	ENOG4107QX8	SPFH domain, Band 7 family protein
ebA2634	ENOG4105DP0	ferredoxin-NADP reductase
ebA2637	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
ebA2638	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
ebA2644	ENOG4105E02	MotA TolQ exbB proton channel
ebA2645	ENOG4105M8F	Biopolymer transport protein exbD tolR
ebA2650	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
ebA2652	ENOG4105KCK	Peptidoglycan-associated lipoprotein
ebA2654	ENOG4105UFD	tol-pal system protein YbgF
ebA2656	ENOG4107VRB	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
ebA2659	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
ebA2666	ENOG4105F5W	AtP-binding protein
ebA2677	ENOG4105D70	Integrase catalytic subunit
ebA2680	ENOG4105F5W	AtP-binding protein
ebA2684	ENOG4105ZTP	Protein of unknown function (DUF1376)
ebA2691	ENOG41067CV	Integrase
ebA2699	ENOG4105CEN	a g-specific adenine glycosylase
ebA2702	ENOG4105BZU	Histidine kinase
ebA2706	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
ebA2710	ENOG4105C32	Amino acid ABC transporter (Permease)
ebA2712	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
ebA2713	ENOG4105EN6	Membrane
ebA2717	ENOG4105C5X	domain protein
ebA2719	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
ebA2720	ENOG4105E0C	molybdate abc transporter
ebA2721	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
ebA2722	ENOG4107QYX	exodeoxyribonuclease v alpha
ebA2723	ENOG4107QKA	exodeoxyribonuclease V beta
ebA2724	ENOG4105DSY	exodeoxyribonuclease V, gamma
ebA274	ENOG4105C0D	helicase
ebA2741	ENOG4105CZN	Potassium uptake protein
ebA2742	ENOG410865Q	Potassium uptake protein
ebA2749	ENOG4108IEG	Formate dehydrogenase Alpha subunit
ebA275	ENOG4108I5C	dEAD DEAH box helicase
ebA2762	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
ebA2768	ENOG4105CHU	acetyl-coa acetyltransferase
ebA2789	ENOG4105CFP	Peptidase U32
ebA2792	ENOG4105C5H	ABC transporter
ebA2794	ENOG4108EQA	pts system
ebA2795	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
ebA2804	ENOG4105BZU	Histidine kinase
ebA2806	ENOG4105DWV	Homoserine O-trans-acetylase
ebA2809	ENOG4105DWV	Homoserine O-trans-acetylase
ebA2811	ENOG4105BZU	Histidine kinase
ebA2813	ENOG4105EYM	Major Facilitator superfamily
ebA2817	ENOG41077A9	carbonic anhydrase
ebA2819	ENOG4105C25	Primosomal protein n'
ebA2822	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
ebA2824	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
ebA2825	ENOG4105C1A	potassium transporter peripheral membrane
ebA2828	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
ebA2830	ENOG4105ES5	Histidine kinase
ebA2833	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
ebA284	ENOG4105C4R	Atp-dependent dna helicase
ebA2841	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
ebA2842	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
ebA2846	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
ebA2847	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
ebA2848	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
ebA2851	ENOG4105DDY	UPF0142 protein ycaO
ebA2865	ENOG4105VEQ	Cold shock protein
ebA2867	ENOG4108UW5	maltose o-acetyltransferase
ebA2869	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
ebA2875	ENOG4105K8R	UPF0145 protein
ebA2876	ENOG4105C5H	ABC transporter
ebA2880	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
ebA2889	ENOG4105EAQ	(twin-arginine translocation) pathway signal
ebA2890	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
ebA2896	ENOG4105BZU	Histidine kinase
ebA2907	ENOG4105FA0	parb-like partition protein
ebA2912	ENOG4107QJE	Chromosome Partitioning Protein
ebA2913	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
ebA2915	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
ebA2918	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
ebA2924	ENOG4105BZU	Histidine kinase
ebA293	ENOG4105F5W	AtP-binding protein
ebA2933	ENOG4108NWD	Cytochrome
ebA2935	ENOG4105QAX	Iron-sulfur
ebA2936	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
ebA2944	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
ebA2945	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
ebA2950	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
ebA2951	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
ebA2953	ENOG4105D0M	Protease HtpX homolog
ebA2954	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
ebA2958	ENOG4108WZM	domain protein
ebA2961	ENOG4105C79	DNA protecting protein DprA
ebA2962	ENOG4108RPN	Protein smg homolog
ebA2963	ENOG4105C9U	ATP-dependent DNA helicase RecQ
ebA2965	ENOG4108EQM	faD-dependent pyridine nucleotide-disulfide oxidoreductase
ebA2969	ENOG4105C0H	protease
ebA2970	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
ebA2973	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
ebA2976	ENOG4105I08	Pseudouridine synthase
ebA2982	ENOG4105DH7	May be involved in recombination (By similarity)
ebA2985	ENOG4105BZU	Histidine kinase
ebA2987	ENOG4105BZU	Histidine kinase
ebA2992	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
ebA2993	ENOG4105C1G	acyl-Coa dehydrogenase
ebA2995	ENOG4105ETT	transcriptional Regulator, LysR family
ebA2996	ENOG4105C26	Dehydrogenase
ebA2999	ENOG4107RAZ	it plays a direct role in the translocation of protons across the membrane (By similarity)
ebA3000	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
ebA3003	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
ebA3004	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
ebA3006	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
ebA3007	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
ebA3008	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
ebA3016	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
ebA3019	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
ebA3021	ENOG4105BZU	Histidine kinase
ebA3026	ENOG4105E7A	Glutamine amidotransferase
ebA3029	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
ebA303	ENOG4105CB2	alcohol dehydrogenase
ebA3030	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
ebA3033	ENOG4105DFF	Rod shape-determining protein mreb
ebA3040	ENOG4105CJN	penicillin-binding protein
ebA3041	ENOG4105CNI	cell division protein FtsW
ebA3044	ENOG4105DZ1	carboxypeptidase
ebA3046	ENOG4105F0I	Aminotransferase
ebA3048	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
ebA3050	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
ebA3053	ENOG4105C4R	Atp-dependent dna helicase
ebA3055	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
ebA3056	ENOG4106WHD	Tetrathionate reductase
ebA306	ENOG4105CHU	acetyl-coa acetyltransferase
ebA3060	ENOG4108ZXC	Two component transcriptional regulator, luxr family
ebA3063	ENOG4106AFQ	Histidine kinase
ebA3067	ENOG4105MPD	Cytochrome
ebA3069	ENOG4109066	lysm domain bon superfamily protein
ebA3077	ENOG4105C0B	DNA polymerase III (alpha subunit)
ebA3079	ENOG4107F83	nucleotidyltransferase DNA polymerase involved in DNA
ebA3086	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
ebA3087	ENOG4108RPX	mosc domain containing protein
ebA3091	ENOG4106BRA	Membrane
ebA3110	ENOG4105EYH	Exonuclease
ebA3111	ENOG4107RH8	nuclease SbcCD subunit D
ebA3114	ENOG4107QS8	(LipO)protein
ebA3118	ENOG4105CPQ	Dehydrogenase
ebA3120	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
ebA3134	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
ebA3138	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
ebA314	ENOG4107QSA	Oxaloacetate decarboxylase
ebA3143	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
ebA3149	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
ebA3150	ENOG4105DQU	oxidoreductase, subunit beta
ebA3151	ENOG4105BZU	Histidine kinase
ebA3157	ENOG4105C0P	Mg chelatase subunit ChlI
ebA3158	ENOG4105C2C	drug resistance transporter, Bcr CflA
ebA316	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
ebA3167	ENOG4108IV0	ABC, transporter
ebA3169	ENOG4105C0Z	ABC transporter
ebA3170	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
ebA3172	ENOG4105C32	Amino acid ABC transporter (Permease)
ebA3175	ENOG4105CP9	extracellular ligand-binding receptor
ebA318	ENOG4105EQN	UPF0261 protein
ebA3180	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
ebA3184	ENOG4105C3R	Methionine synthase
ebA3186	ENOG4105E3J	oxidoreductase
ebA3192	ENOG4105CJ2	(LipO)protein
ebA3193	ENOG4108VN5	Inherit from COG: PepSY-associated TM helix
ebA3202	ENOG4105CA0	peroxidase
ebA321	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
ebA3210	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
ebA3224	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
ebA3236	ENOG4105EHZ	conserved protein UCP016719
ebA3244	ENOG4105GAV	receptor
ebA3250	ENOG4105EE5	Membrane protein terC
ebA3251	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
ebA3283	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
ebA33	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
ebA3304	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
ebA3316	ENOG4105E0M	Sulfatase
ebA332	ENOG4105D25	secreted protein
ebA3320	ENOG4105DHQ	Histidine kinase
ebA3323	ENOG4105CGK	Exodeoxyribonuclease III
ebA3324	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
ebA3328	ENOG4108J2R	molybdopterin oxidoreductase
ebA3329	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
ebA3338	ENOG4105F5W	AtP-binding protein
ebA3365	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
ebA3368	ENOG4105CHR	reductase
ebA3377	ENOG4105CYM	Glutathione S-transferase
ebA3379	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
ebA3385	ENOG4107SC1	transglycosylase
ebA3386	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
ebA3389	ENOG4105C7B	Threonine dehydratase
ebA3390	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
ebA3391	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
ebA3393	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
ebA3394	ENOG4108IUZ	ABC transporter
ebA3396	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
ebA3399	ENOG4107TH8	cina domain protein
ebA3402	ENOG4108ZAI	phosphatidylglycerophosphatase a
ebA3404	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
ebA3410	ENOG4105D4A	Cell wall formation (By similarity)
ebA342	ENOG41083IP	HIT family
ebA3426	ENOG4105C32	Amino acid ABC transporter (Permease)
ebA3429	ENOG4108IV0	ABC, transporter
ebA3430	ENOG4105C0Z	ABC transporter
ebA3433	ENOG4105CEY	Amp-dependent synthetase and ligase
ebA3439	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
ebA3446	ENOG4105CW7	secretion protein, HlyD family
ebA3448	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
ebA3463	ENOG4105C7B	Threonine dehydratase
ebA3466	ENOG4105ECA	phosphoserine phosphatase homoserine phosphotransferase bifunctional protein
ebA3467	ENOG4105CIY	formyltetrahydrofolate deformylase
ebA3469	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
ebA3470	ENOG4105VEQ	Cold shock protein
ebA3478	ENOG4108KS2	transglutaminase domain protein
ebA348	ENOG4105VFQ	Histone family protein nucleoid-structuring protein H-NS
ebA3480	ENOG4107QX9	Thiol disulfide interChange protein
ebA3483	ENOG4108RH0	Crea protein
ebA3490	ENOG4106T14	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
ebA3494	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
ebA3495	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
ebA3497	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
ebA3500	ENOG4105DVT	helicase
ebA3507	ENOG4105BZU	Histidine kinase
ebA3508	ENOG4105WH1	Two component transcriptional regulator luxr family
ebA3514	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
ebA3516	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
ebA3518	ENOG41060IM	Heme exporter protein
ebA3521	ENOG4105DA4	cytochrome c-type biogenesis protein
ebA3522	ENOG4107QX9	Thiol disulfide interChange protein
ebA3525	ENOG4105KWW	Biogenesis protein
ebA3526	ENOG4108M1T	Cytochrome c-type biogenesis protein
ebA3534	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
ebA3535	ENOG4107RES	phosphoglycerol transferase I
ebA3537	ENOG4107QN1	sodium solute
ebA3542	ENOG4108UKI	Enoyl-CoA hydratase
ebA3543	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
ebA3544	ENOG4108ZJI	phenylacetic acid degradation protein
ebA3547	ENOG4105CRS	phenylacetate-CoA oxygenase PaaG subunit
ebA3548	ENOG4105N76	Phenylacetate-CoA oxygenase, subunit
ebA3550	ENOG4105D9S	phenylacetate-CoA oxygenase PaaI subunit
ebA3551	ENOG4108ZA2	phenylacetate-CoA oxygenase PaaJ subunit
ebA3553	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
ebA3559	ENOG4105C0Z	ABC transporter
ebA3560	ENOG4108IV0	ABC, transporter
ebA3561	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
ebA3563	ENOG4105C1J	atp-dependent rna helicase
ebA3564	ENOG4107YIM	Involved in the transcription termination process (By similarity)
ebA3566	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
ebA3567	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
ebA3571	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
ebA3572	ENOG4105VF7	tolerance protein
ebA3574	ENOG41080TK	Universal stress protein
ebA3576	ENOG4108ZCF	integral membrane protein
ebA3580	ENOG4105CJ1	ABC, transporter
ebA3583	ENOG4108U78	Glutathione S-transferase
ebA3584	ENOG4107U2T	alpha beta
ebA3590	ENOG4105XPQ	lipid carrier protein
ebA3592	ENOG4106RZ4	Peptidase U32
ebA3595	ENOG4105CFP	Peptidase U32
ebA3601	ENOG4105XRQ	Xanthine dehydrogenase accessory factor
ebA3606	ENOG4107RB3	L-asparaginase
ebA3608	ENOG4105CK7	Sodium proline symporter
ebA3609	ENOG4105C8Y	Acetylornithine aminotransferase
ebA3613	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
ebA3614	ENOG4105C75	arginyL-tRNA synthetase
ebA3619	ENOG4105C7I	Dehydrogenase
ebA3621	ENOG4105DFH	Transport of potassium into the cell (By similarity)
ebA3623	ENOG4105DCF	alanine dehydrogenase
ebA3624	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
ebA3628	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
ebA3630	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
ebA3634	ENOG4108Z6Z	Transcriptional regulator
ebA3637	ENOG41077A9	carbonic anhydrase
ebA3639	ENOG4105CHU	acetyl-coa acetyltransferase
ebA3640	ENOG4105C1G	acyl-Coa dehydrogenase
ebA3650	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
ebA3654	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
ebA3657	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
ebA3662	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
ebA3666	ENOG4107RQ2	Cytochrome c oxidase, subunit I
ebA3674	ENOG4105CDY	transcriptional regulatory protein
ebA3678	ENOG4105KQC	Competence protein
ebA3682	ENOG4105C1J	atp-dependent rna helicase
ebA3688	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
ebA3690	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
ebA3691	ENOG4105E39	Enoyl-CoA hydratase
ebA3695	ENOG4107QN1	sodium solute
ebA37	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
ebA3727	ENOG4108S01	response regulator
ebA3735	ENOG4105C9Q	fumarate hydratase class II
ebA3736	ENOG4105DRR	Transcriptional regulator, GntR family
ebA3738	ENOG4105D5P	Methylmalonyl-coA mutase
ebA3742	ENOG4107QX3	carboxylase
ebA3743	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
ebA3747	ENOG4105CGZ	zinc metallopeptidase
ebA3750	ENOG4105R1U	AraC Family Transcriptional Regulator
ebA3751	ENOG4105DJ2	Major Facilitator Superfamily
ebA3757	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
ebA3766	ENOG4105D5P	Methylmalonyl-coA mutase
ebA3772	ENOG4105MRD	Phage derived protein Gp49-like (DUF891)
ebA3777	ENOG4106IJN	integrase catalytic domain-containing protein
ebA3781	ENOG4105F5W	AtP-binding protein
ebA3785	ENOG4105BZU	Histidine kinase
ebA3787	ENOG4105DQR	SNARE associated Golgi
ebA3792	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
ebA3794	ENOG4105BZU	Histidine kinase
ebA3801	ENOG4105WH1	Two component transcriptional regulator luxr family
ebA3803	ENOG4105CQB	FAD linked oxidase domain protein
ebA3804	ENOG4108YXU	transcriptional regulator AsnC family
ebA3808	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
ebA381	ENOG4107QJE	Chromosome Partitioning Protein
ebA3810	ENOG4105PM1	preprotein translocase subunit SecE
ebA3812	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
ebA3814	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
ebA3816	ENOG4108VZM	50s ribosomal protein L10
ebA3818	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
ebA3819	ENOG4107QR0	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
ebA3820	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
ebA3822	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
ebA3824	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
ebA3826	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
ebA3828	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
ebA3829	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
ebA3831	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ebA3832	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
ebA3833	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
ebA3834	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
ebA3839	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ebA3841	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
ebA3844	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
ebA3846	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
ebA385	ENOG4105E5H	Transposase
ebA3850	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
ebA3852	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
ebA3853	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
ebA3856	ENOG4105CMR	udp-glucose 4-epimerase
ebA3857	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
ebA3858	ENOG4107RDB	Major Facilitator
ebA3859	ENOG4108UUM	single-stranded DNA-binding protein
ebA3862	ENOG4105C87	Aminotransferase class I and II
ebA3867	ENOG4105CUZ	uba thif-type nad fad binding protein
ebA3873	ENOG4105BZS	acriflavin resistance protein
ebA3876	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
ebA3879	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
ebA3881	ENOG4105EUB	pirin domain protein
ebA3882	ENOG4108MTB	glycosyl transferase family
ebA3883	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
ebA3884	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
ebA3889	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
ebA3890	ENOG4105CHM	Aminotransferase
ebA3892	ENOG4107TUY	Histidine kinase
ebA3894	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
ebA3906	ENOG4105CZM	Major Facilitator
ebA3914	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
ebA3917	ENOG4107QR9	Iron-sulfur cluster binding protein
ebA3918	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
ebA3924	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
ebA3931	ENOG4105CCT	upf0313 protein
ebA3939	ENOG4105GAV	receptor
ebA3942	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
ebA3949	ENOG4105D1S	lipid A biosynthesis
ebA3950	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
ebA3956	ENOG4105DR4	Methyltransferase
ebA3958	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
ebA3959	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
ebA3964	ENOG4105C03	ribonuclease
ebA3966	ENOG4108Z03	MAF-like protein
ebA3968	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
ebA3971	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
ebA3972	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
ebA3979	ENOG4105CUV	Homoserine Kinase
ebA3981	ENOG4108URH	decarboxylase
ebA3982	ENOG4105C2M	dna polymerase I
ebA3983	ENOG4105BZG	amino acid carrier protein
ebA3985	ENOG4107VDP	teichoic acid biosynthesis
ebA3992	ENOG4105BZ1	(ABC) transporter
ebA3995	ENOG4107543	(lipo)polysaccharide
ebA3996	ENOG4107RJ7	Glycosyl transferase (Group 1
ebA3997	ENOG4105D16	lipopolysaccharide heptosyltransferase i
ebA3998	ENOG4105XA0	heptosyltransferase ii
ebA3999	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
ebA4001	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
ebA4005	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
ebA4008	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
ebA4011	ENOG4108YZT	Adenosylcobinamide kinase
ebA4019	ENOG4105EHG	Permease protein
ebA4020	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
ebA4023	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
ebA4025	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
ebA4027	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
ebA4029	ENOG4105E7Q	Cob(II)yrinic acid a,c-diamide reductase
ebA4033	ENOG4108ZYK	Acyl carrier protein phosphodiesterase
ebA4035	ENOG4105D64	Mechanosensitive ion channel
ebA4038	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
ebA4040	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
ebA4043	ENOG4105C6K	Malic enzyme
ebA4047	ENOG41061WM	D-Alanyl-D-Alanine
ebA4048	ENOG4108FUF	Transcriptional regulator, IclR family
ebA4050	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
ebA4052	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
ebA4056	ENOG4105FE9	pseudouridine synthase
ebA4058	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
ebA4061	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
ebA4065	ENOG4105CX6	glutaminyL-tRNA synthetase
ebA4066	ENOG4105CUY	Mechanosensitive ion channel
ebA4068	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
ebA4074	ENOG4105CQ7	ATP-dependent helicase
ebA4075	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
ebA4078	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
ebA4079	ENOG4105CDU	Replicative dna helicase
ebA4098	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
ebA4099	ENOG4105T95	Thiol disulfide interChange protein
ebA4104	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
ebA4105	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
ebA4109	ENOG4108JEB	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
ebA4111	ENOG4108194	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
ebA4116	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
ebA4117	ENOG4105CUX	Signal transduction histidine kinase
ebA4121	ENOG4105C5F	glutamine synthetase
ebA4125	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
ebA4126	ENOG4105X23	Endonuclease Exonuclease phosphatase
ebA4127	ENOG4105DZQ	phospholipase D Transphosphatidylase
ebA4133	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
ebA4139	ENOG4105C3G	gtp-binding protein
ebA4142	ENOG41063Z6	transcriptional regulator, lysR family
ebA4143	ENOG4108MN8	Membrane
ebA4148	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
ebA4149	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
ebA4154	ENOG4108ZXC	Two component transcriptional regulator, luxr family
ebA4156	ENOG4105BZU	Histidine kinase
ebA4158	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
ebA4159	ENOG4108RA0	tripartite ATP-independent periplasmic transporter, DctQ component
ebA4162	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
ebA4167	ENOG4107RF4	Phosphodiesterase
ebA4169	ENOG4107QHF	type ii secretion system protein e
ebA4173	ENOG4105DJV	ribulose-phosphate 3-epimerase
ebA4174	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
ebA4186	ENOG4105C47	NADH ubiquinone oxidoreductase 20 kda subunit
ebA4187	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
ebA4190	ENOG4108JPZ	Monovalent cation H antiporter subunit D
ebA4192	ENOG4107TDF	Formate hydrogenlyase subunit 4
ebA4193	ENOG4108JPZ	Monovalent cation H antiporter subunit D
ebA4199	ENOG4105DDQ	anthranilate synthase
ebA4200	ENOG4107QYG	anthranilate phosphoribosyltransferase
ebA4201	ENOG4105DK0	Indole-3-glycerol phosphate synthase
ebA4211	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
ebA4224	ENOG4105C9U	ATP-dependent DNA helicase RecQ
ebA4227	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
ebA4228	ENOG4105BZ9	Cytochrome C oxidase, subunit I
ebA4229	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
ebA4231	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
ebA4237	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
ebA4238	ENOG4108ZX6	Electron transport protein SCO1 SenC
ebA4241	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
ebA4244	ENOG4108Z9W	Outer membrane porin
ebA4247	ENOG4107V1M	polysaccharide export protein
ebA4250	ENOG4108QV3	biosynthesis protein
ebA4257	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
ebA426	ENOG4105T95	Thiol disulfide interChange protein
ebA4262	ENOG4105CPK	Glycosyl transferase (Group 1
ebA4263	ENOG4105CAQ	asparagine synthetase
ebA4264	ENOG4105E2K	Glycosyl transferase (Group 1
ebA4265	ENOG4105CAQ	asparagine synthetase
ebA4268	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
ebA4275	ENOG4107TYR	Glycosyl Transferase
ebA4291	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
ebA4297	ENOG4105CEY	Amp-dependent synthetase and ligase
ebA4304	ENOG4105K64	Glycosyl transferase, family 2
ebA4308	ENOG4105EKQ	RNA-directed DNA polymerase
ebA4330	ENOG4105CAS	nag kinase
ebA4332	ENOG4105VN1	Heat shock protein
ebA4334	ENOG4108TIT	dATP pyrophosphohydrolase
ebA4339	ENOG4105C9M	aspartyl-trna synthetase
ebA4343	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
ebA4346	ENOG4107QHF	type ii secretion system protein e
ebA4348	ENOG4105CRE	cytochrome C
ebA4351	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ebA4362	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
ebA4365	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
ebA4370	ENOG4105VCC	30S ribosomal protein S21
ebA4371	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
ebA4373	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
ebA4376	ENOG4108Z66	YbaK ebsC protein
ebA4380	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
ebA4383	ENOG4105DJF	DNA polymerase III, delta' subunit
ebA4386	ENOG4105C8T	Leucyl-tRNA synthetase
ebA4390	ENOG4105C4R	Atp-dependent dna helicase
ebA4391	ENOG4107QJE	Chromosome Partitioning Protein
ebA4392	ENOG4105C6K	Malic enzyme
ebA4396	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
ebA4398	ENOG4105C0B	DNA polymerase III (alpha subunit)
ebA4399	ENOG4105D3R	alkyl hydroperoxide reductase
ebA4402	ENOG4105CHH	sulfate transporter
ebA4404	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
ebA4409	ENOG4105D1F	ATP-binding protein
ebA4412	ENOG4105DHP	deoxycytidine triphosphate deaminase
ebA4413	ENOG4105CXN	decarboxylase
ebA4415	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
ebA4434	ENOG4108Z7G	MaoC domain protein dehydratase
ebA4438	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
ebA4439	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
ebA4440	ENOG4105CTB	Polyprenyl synthetase
ebA4444	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
ebA4447	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
ebA4448	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
ebA4449	ENOG4105DTN	riboflavin biosynthesis protein ribF
ebA4451	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
ebA4453	ENOG4105K8N	protein family UPF0079, ATPase
ebA4454	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
ebA4456	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
ebA4458	ENOG4105CHR	reductase
ebA4460	ENOG4105KHC	sulfurtransferase
ebA4462	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
ebA4463	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
ebA4466	ENOG4105E0F	Histidine kinase
ebA4468	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
ebA4473	ENOG4108I9X	Isocitrate lyase
ebA4476	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
ebA4477	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
ebA4482	ENOG4105KDC	50s ribosomal protein l28
ebA4490	ENOG4105CQB	FAD linked oxidase domain protein
ebA4491	ENOG4105EU8	FAD linked oxidase domain protein
ebA4492	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
ebA4496	ENOG4105D7N	magnesium and cobalt transport protein CorA
ebA4497	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
ebA4498	ENOG4105W8H	transhydrogenase (subunit alpha
ebA4500	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
ebA4502	ENOG4105C1J	atp-dependent rna helicase
ebA4504	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
ebA4507	ENOG4105BZ7	extracellular solute-binding protein family 1
ebA4509	ENOG4107T6V	glycerophosphoryl diester phosphodiesterase
ebA4512	ENOG4105EAH	synthase
ebA4517	ENOG4105DU6	RNA polymerase
ebA452	ENOG4105E5H	Transposase
ebA4535	ENOG4107QN2	dihydrolipoyl dehydrogenase
ebA4544	ENOG4105BZ9	Cytochrome C oxidase, subunit I
ebA4547	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
ebA4558	ENOG4105DIA	mandelate racemase muconate lactonizing
ebA4561	ENOG4107RP9	extracellular solute-binding protein, family 3
ebA4562	ENOG4105DRP	amino acid AbC transporter
ebA4564	ENOG4105EAD	ABC transporter
ebA4567	ENOG4105CDA	abc transporter atp-binding protein
ebA4568	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
ebA4576	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
ebA4578	ENOG4105E33	succinate dehydrogenase
ebA4588	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
ebA4589	ENOG4105DQU	oxidoreductase, subunit beta
ebA4598	ENOG4105C28	cystathionine
ebA4612	ENOG4108Q5Y	Membrane
ebA4614	ENOG4108ZJF	Glcg protein
ebA4617	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
ebA4623	ENOG4105C0A	alcohol dehydrogenase
ebA4625	ENOG4105C26	Dehydrogenase
ebA4627	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
ebA4628	ENOG4105DKD	Incises the DNA at the 3' side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than UvrC. Not able to incise the 5' site of a lesion. When a lesion remains because UvrC is not able to induce the 3' incision, Cho incises the DNA. Then UvrC makes the 5' incision. The combined action of Cho and UvrC broadens the substrate range of nucleotide excision repair (By similarity)
ebA4638	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
ebA4639	ENOG4105C4M	(Ubiquinol oxidase) subunit I
ebA4644	ENOG4105CAH	Chromate
ebA4655	ENOG4108R6W	Transcriptional regulator, ARAC family
ebA4656	ENOG4105C1G	acyl-Coa dehydrogenase
ebA4657	ENOG4107QX3	carboxylase
ebA4661	ENOG4105CEY	Amp-dependent synthetase and ligase
ebA4662	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
ebA4666	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
ebA4668	ENOG4107QUY	Guanine deaminase
ebA4676	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
ebA4678	ENOG4105C6T	cysteine synthase
ebA4696	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
ebA4700	ENOG4107RID	5-oxoprolinase (ATP-hydrolyzing)
ebA4701	ENOG4107TYC	hydantoinase B oxoprolinase
ebA4702	ENOG4105HKX	acetone carboxylase, gamma subunit
ebA4717	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
ebA4722	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
ebA4724	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ebA4725	ENOG4105C34	Pseudouridine synthase
ebA4726	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
ebA4728	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
ebA4729	ENOG4105CHR	reductase
ebA4732	ENOG4108NVM	synthesis repressor PhaR
ebA4733	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
ebA4736	ENOG4105D78	K07001 NTE family protein
ebA4737	ENOG4105CQB	FAD linked oxidase domain protein
ebA474	ENOG4108RS6	transposase
ebA4742	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
ebA4743	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
ebA4746	ENOG4108Z4U	Ferredoxin
ebA4749	ENOG4105CEY	Amp-dependent synthetase and ligase
ebA4751	ENOG4105C7K	acetolactate synthase
ebA4753	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
ebA4754	ENOG4105D8G	Major Facilitator superfamily
ebA4755	ENOG4105ERG	peptidase m48, ste24p
ebA4757	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
ebA4758	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
ebA4760	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
ebA4761	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
ebA4770	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
ebA4775	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
ebA4776	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
ebA4777	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
ebA4778	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
ebA478	ENOG4105C01	Dihydroxy-acid dehydratase
ebA4783	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
ebA4785	ENOG4105C28	cystathionine
ebA4786	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
ebA4788	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
ebA4792	ENOG4105C8N	cysteinyl-tRNA synthetase
ebA4793	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
ebA4794	ENOG4105CFG	Acts as a chaperone (By similarity)
ebA4795	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ebA4796	ENOG4105D9P	serine threonine protein kinase
ebA4802	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
ebA4803	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
ebA4805	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
ebA4808	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
ebA4812	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
ebA4813	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
ebA4815	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
ebA4816	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
ebA4819	ENOG4105HBR	Rna-binding protein
ebA4820	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
ebA4823	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
ebA4824	ENOG4105EEI	dihydropteroate synthase
ebA4825	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
ebA4826	ENOG4105PWN	phosphate abc transporter
ebA4828	ENOG4105C8U	phosphate abc transporter
ebA4829	ENOG4105C8U	phosphate abc transporter
ebA4830	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
ebA4831	ENOG4105CP7	Triose-phosphate isomerase
ebA4835	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
ebA4836	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
ebA4837	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
ebA4838	ENOG4105GKE	subunit e
ebA4840	ENOG4107QIZ	NADH dehydrogenase
ebA4841	ENOG4108IEH	NADH dehydrogenase subunit g
ebA4841	ENOG4108IEH	NADH dehydrogenase subunit g
ebA4842	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
ebA4843	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
ebA4844	ENOG4105DF2	NADH dehydrogenase subunit j
ebA4846	ENOG4105D65	subunit l
ebA4847	ENOG4105C8S	subunit m
ebA4848	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
ebA485	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
ebA4853	ENOG4105PGM	cation diffusion facilitator family transporter
ebA486	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
ebA4863	ENOG4105CVE	Lytic murein transglycosylase
ebA4864	ENOG4108RRZ	Transcription elongation factor GreB
ebA4865	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
ebA4871	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
ebA4872	ENOG4106RE7	Cytochrome
ebA4874	ENOG4106RE7	Cytochrome
ebA4877	ENOG4105CSM	endonuclease III
ebA4878	ENOG4105DZB	Electron transport complex
ebA4882	ENOG4105D6A	Electron transport complex
ebA4884	ENOG4108R3D	Electron transport complex
ebA4887	ENOG4105DGN	Electron transport complex
ebA4888	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
ebA4890	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
ebA4891	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
ebA4892	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
ebA4893	ENOG4107QVT	Binding-protein-dependent transport systems, inner membrane component
ebA4906	ENOG4108WWZ	General secretion pathway protein J
ebA4908	ENOG4105X5Z	General secretion pathway protein I
ebA4913	ENOG4105D7Q	type ii secretion system
ebA4914	ENOG4107QHF	type ii secretion system protein e
ebA4915	ENOG4105GVR	general secretion pathway protein D
ebA4918	ENOG4107QKW	extracellular solute-binding protein family 1
ebA4921	ENOG4105K4H	Nlp p60 protein
ebA4939	ENOG4105EKQ	RNA-directed DNA polymerase
ebA4946	ENOG4108IAB	Phoh family
ebA4948	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ebA4951	ENOG4105CHM	Aminotransferase
ebA4952	ENOG4105D6E	homoserine dehydrogenase
ebA4956	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
ebA4962	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
ebA4963	ENOG4105ED1	spovr family
ebA4964	ENOG4106AKX	UPF0229 protein
ebA4966	ENOG4105CYN	Serine protein kinase
ebA4969	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
ebA497	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
ebA4970	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
ebA4971	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
ebA4973	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
ebA4979	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
ebA4984	ENOG4105CB5	ATP-dependent DNA helicase recG
ebA4989	ENOG4105D2S	major facilitator superfamily
ebA50	ENOG4105CKW	Inner membrane protein yedI
ebA5001	ENOG4105D6J	arsenicaL-resistance protein
ebA5005	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
ebA5014	ENOG4108T5I	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
ebA5018	ENOG4105CC0	LysR family Transcriptional regulator
ebA5020	ENOG4105ECR	NmrA family
ebA5023	ENOG4105DS1	cytochrome b561
ebA503	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
ebA5035	ENOG41066T0	asmA family
ebA5055	ENOG4105D94	Major Facilitator Superfamily
ebA5056	ENOG4106NZI	LysR family Transcriptional regulator
ebA5073	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
ebA5076	ENOG4108K3A	Glutathione S-transferase
ebA5077	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
ebA5078	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
ebA5085	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
ebA5086	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
ebA5087	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
ebA5091	ENOG4105CJR	Integral membrane protein (MviN
ebA5095	ENOG4105C8Y	Acetylornithine aminotransferase
ebA5096	ENOG4105DBV	ornithine carbamoyltransferase
ebA5097	ENOG4105CDH	Citrulline--aspartate ligase
ebA5101	ENOG4108VPT	UPF0234 protein
ebA511	ENOG4107RRE	RNA-directed DNA polymerase
ebA5117	ENOG4108HRK	Histidine kinase
ebA5123	ENOG4105P8F	nudix hydrolase
ebA5128	ENOG4105C59	p-type ATPase
ebA5131	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
ebA5134	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
ebA5139	ENOG4105CY0	Metallo-Beta-Lactamase
ebA5140	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
ebA5141	ENOG4105EYW	Ion transport protein
ebA5149	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
ebA5151	ENOG4105D4P	Coproporphyrinogen iii oxidase
ebA5154	ENOG4105C59	p-type ATPase
ebA5156	ENOG4105WQ5	TonB family
ebA5160	ENOG4105CG3	alpha amylase, catalytic region
ebA5166	ENOG4105D25	secreted protein
ebA5169	ENOG4107R13	MMPL domain protein
ebA5182	ENOG4105I7I	quinohemoprotein amine dehydrogenase gamma subunit
ebA5186	ENOG4105BZ1	(ABC) transporter
ebA5191	ENOG4105CFP	Peptidase U32
ebA5193	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
ebA5199	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
ebA5202	ENOG4105CHU	acetyl-coa acetyltransferase
ebA5205	ENOG4105C2Y	STE24 endopeptidase EC 3.4.24.84
ebA5206	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
ebA5208	ENOG4107QP8	phosphohexose isomerase
ebA5215	ENOG4105VFB	Binds the 23S rRNA (By similarity)
ebA5226	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
ebA5230	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
ebA5236	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
ebA5242	ENOG4105F5W	AtP-binding protein
ebA5251	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
ebA5255	ENOG4106RHG	Yeca family
ebA5263	ENOG4105K5B	UPF0225 protein
ebA5264	ENOG4107QM5	aconitate hydratase
ebA5265	ENOG4107QIJ	Aconitate hydratase 2
ebA527	ENOG4105W5Q	DNA repair protein (RadC
ebA5271	ENOG4105CAQ	asparagine synthetase
ebA5272	ENOG4108DIG	cyanophycin synthetase
ebA5273	ENOG4105DER	m42 family
ebA5278	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
ebA5282	ENOG4105DCU	2-hydroxyglutaryl-CoA dehydratase
ebA5286	ENOG4105CIZ	coA-substrate-specific enzyme activase
ebA529	ENOG4108R7K	Metal Dependent Phosphohydrolase
ebA5293	ENOG4105C0B	DNA polymerase III (alpha subunit)
ebA5298	ENOG4105EC5	6-oxocyclohex-1-ene-1-carbonyl-CoA
ebA5300	ENOG4105CHR	reductase
ebA5304	ENOG4105C32	Amino acid ABC transporter (Permease)
ebA5307	ENOG4105C0Z	ABC transporter
ebA5309	ENOG4108IV0	ABC, transporter
ebA5311	ENOG4105D2S	major facilitator superfamily
ebA5317	ENOG4105CEY	Amp-dependent synthetase and ligase
ebA5318	ENOG4105E9F	Enoyl-CoA hydratase
ebA5319	ENOG4105CHU	acetyl-coa acetyltransferase
ebA5321	ENOG4105CSU	acyl-Coa dehydrogenase
ebA5341	ENOG4105F5W	AtP-binding protein
ebA5346	ENOG410600T	transposase
ebA5358	ENOG4108Z9W	Outer membrane porin
ebA536	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
ebA5362	ENOG4105RD8	TRAP dicarboxylate transporter
ebA5367	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
ebA537	ENOG4105KPV	Transcriptional regulator
ebA5375	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
ebA5390	ENOG4105V9J	phenylacetic acid degradation operon negative regulatory protein
ebA5392	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
ebA5393	ENOG4107QY8	reductase
ebA5393	ENOG4107QY8	reductase
ebA5395	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
ebA5406	ENOG4108Z6B	deaminase
ebA5408	ENOG4108QQZ	ErfK YbiS YcfS YnhG family protein
ebA5412	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
ebA5414	ENOG4105HHA	aminodeoxychorismate lyase
ebA5415	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
ebA5417	ENOG4107QRG	dna polymerase iii
ebA5421	ENOG4105F8V	Hydrolase, tatD family
ebA5425	ENOG4105D82	Glutamate dehydrogenase
ebA5427	ENOG4105CH2	amidohydrolase
ebA5428	ENOG4105CV6	ABC transporter, permease
ebA5430	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
ebA5433	ENOG4105DAN	ATP-dependent protease
ebA5437	ENOG4105CGF	Aromatic amino acid aminotransferase
ebA5438	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
ebA5441	ENOG4105C03	ribonuclease
ebA5443	ENOG4105EI2	Pseudouridine synthase
ebA5444	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
ebA5450	ENOG4108UHJ	MAF-like protein
ebA5452	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
ebA5454	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
ebA5455	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
ebA5456	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
ebA5457	ENOG4105CHR	reductase
ebA5459	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
ebA5461	ENOG4108IYU	L-aspartate oxidase
ebA5463	ENOG4105EMN	RNA polymerase sigma factor
ebA5465	ENOG4105VQK	sigma E regulatory protein, MucB RseB
ebA5470	ENOG4105C0H	protease
ebA5484	ENOG4105EFC	phage portal protein HK97 family
ebA5498	ENOG4105F5W	AtP-binding protein
ebA550	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
ebA551	ENOG4105C26	Dehydrogenase
ebA5511	ENOG4105D70	Integrase catalytic subunit
ebA5514	ENOG4105F5W	AtP-binding protein
ebA5523	ENOG4105E5H	Transposase
ebA553	ENOG4105KJM	monovalent cation h antiporter subunit g
ebA5534	ENOG4105DFP	Integrase
ebA5535	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
ebA5536	ENOG4105C3F	Signal peptidase i
ebA5539	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
ebA554	ENOG4105W4C	monovalent cation H antiporter subunit F
ebA5540	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
ebA5541	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
ebA5544	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
ebA5547	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
ebA5548	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
ebA555	ENOG4105SC1	monovalent cation H antiporter subunit E
ebA5555	ENOG4105CZN	Potassium uptake protein
ebA5556	ENOG410865Q	Potassium uptake protein
ebA556	ENOG4107R4Z	monovalent cation h antiporter subunit d
ebA5576	ENOG4105BZF	Glycosyl transferase (Group 1
ebA5579	ENOG41080IJ	Diacylglycerol kinase
ebA558	ENOG4105D65	subunit l
ebA5582	ENOG4105BZU	Histidine kinase
ebA5611	ENOG4105CD5	CoA-binding domain protein
ebA5612	ENOG4105MSY	salicylate hydroxylase
ebA5616	ENOG4105ERH	Fumarylacetoacetate hydrolase
ebA5619	ENOG4105E9F	Enoyl-CoA hydratase
ebA5620	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
ebA5622	ENOG4105DB1	molybdopterin oxidoreductase
ebA563	ENOG4108RS6	transposase
ebA5630	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
ebA5637	ENOG4105DTQ	mandelate racemase muconate lactonizing
ebA5641	ENOG4105C1G	acyl-Coa dehydrogenase
ebA5643	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
ebA5644	ENOG4108Z9W	Outer membrane porin
ebA5649	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
ebA5652	ENOG4105DTQ	mandelate racemase muconate lactonizing
ebA5658	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
ebA5664	ENOG4105G3Z	GntR family transcriptional regulator
ebA5667	ENOG4105CD5	CoA-binding domain protein
ebA5668	ENOG4105CC9	acyl-Coa dehydrogenase
ebA5669	ENOG4105C1G	acyl-Coa dehydrogenase
ebA5670	ENOG4105KF3	Short-chain dehydrogenase reductase Sdr
ebA5678	ENOG4108ZEY	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
ebA5680	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
ebA5708	ENOG4107ZN8	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
ebA5710	ENOG4105DXI	Major Facilitator superfamily
ebA5712	ENOG4105C4W	S-formylglutathione hydrolase
ebA5715	ENOG4108XG2	Histidine kinase
ebA5720	ENOG4105CRS	phenylacetate-CoA oxygenase PaaG subunit
ebA5721	ENOG4105N76	Phenylacetate-CoA oxygenase, subunit
ebA5722	ENOG4105D9S	phenylacetate-CoA oxygenase PaaI subunit
ebA5723	ENOG4108ZA2	phenylacetate-CoA oxygenase PaaJ subunit
ebA5725	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
ebA5729	ENOG4105CHU	acetyl-coa acetyltransferase
ebA5732	ENOG4105E39	Enoyl-CoA hydratase
ebA5738	ENOG4105C1J	atp-dependent rna helicase
ebA5739	ENOG41088SP	formiminoglutamate hydrolase
ebA5740	ENOG4105CI2	imidazolone-5-propionate hydrolase
ebA5741	ENOG4105CGP	Urocanate hydratase
ebA5742	ENOG4105C84	Histidine ammonia-lyase
ebA5744	ENOG4105BZU	Histidine kinase
ebA5750	ENOG4108XG2	Histidine kinase
ebA5752	ENOG4105WH1	Two component transcriptional regulator luxr family
ebA5760	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
ebA5766	ENOG4105D25	secreted protein
ebA5773	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
ebA5774	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
ebA5783	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
ebA5789	ENOG4108KEZ	Dehydrogenase
ebA5790	ENOG4108JIG	Anaerobic dehydrogenase
ebA5797	ENOG4105CHU	acetyl-coa acetyltransferase
ebA5807	ENOG4108V0P	LemA family
ebA5811	ENOG4105EIF	outer membrane protein W
ebA5815	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
ebA5819	ENOG4105D60	lipoprotein releasing system transmembrane protein
ebA5820	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
ebA5822	ENOG4108EC8	DNA internalization-related competence protein ComEC
ebA5827	ENOG4105E0X	reductase
ebA5829	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
ebA5836	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
ebA5838	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
ebA584	ENOG4105CHC	glucokinase (EC 2.7.1.2)
ebA5840	ENOG4105CHV	Transcription elongation factor NusA
ebA5841	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
ebA5842	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
ebA5843	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
ebA5844	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
ebA5846	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
ebA5850	ENOG4105VUH	addiction module killer protein
ebA5855	ENOG4105CB5	ATP-dependent DNA helicase recG
ebA5857	ENOG4105CY0	Metallo-Beta-Lactamase
ebA587	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
ebA5870	ENOG4107QQG	Dehydrogenase
ebA5881	ENOG4105CPK	Glycosyl transferase (Group 1
ebA5890	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
ebA5895	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
ebA590	ENOG4107TE5	Lipid kinase
ebA5900	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
ebA5903	ENOG4105D3Q	Sugar transferase
ebA5904	ENOG4105J5G	Transferase hexapeptide repeat containing protein
ebA5917	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
ebA5948	ENOG4105F5W	AtP-binding protein
ebA595	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
ebA596	ENOG4105CGF	Aromatic amino acid aminotransferase
ebA598	ENOG4105E0M	Sulfatase
ebA5982	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
ebA5984	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
ebA5986	ENOG4105CE9	30S ribosomal protein S2
ebA5987	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
ebA5988	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
ebA5990	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
ebA5991	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
ebA5992	ENOG4105KNE	Phosphatidate cytidylyltransferase
ebA5994	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
ebA5995	ENOG4105DZP	Membrane-associated zinc metalloprotease
ebA5996	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ebA5998	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
ebA5999	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
ebA600	ENOG4105CKK	Glycosyl transferase, family 2
ebA6000	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
ebA6002	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
ebA6003	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
ebA6011	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
ebA6013	ENOG4106T9E	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
ebA6017	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
ebA6018	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
ebA6021	ENOG4105D1Q	UPF0246 protein
ebA6034	ENOG4105EAC	phosphoserine phosphatase
ebA6035	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
ebA6036	ENOG4107QZF	nitrite reductase NADPH large subunit
ebA6041	ENOG4105BZU	Histidine kinase
ebA6047	ENOG4105DZ0	fad dependent oxidoreductase
ebA6049	ENOG41069P5	Protein slyX homolog
ebA605	ENOG4105C0F	tryptophanase EC 4.1.99.1
ebA6051	ENOG4105BZU	Histidine kinase
ebA6058	ENOG4105BZU	Histidine kinase
ebA6072	ENOG4105EMN	RNA polymerase sigma factor
ebA6075	ENOG4105CHR	reductase
ebA608	ENOG410841Q	phosphoesterase PA-phosphatase related protein
ebA609	ENOG4105C59	p-type ATPase
ebA6096	ENOG4105CHB	tonB-dependent Receptor
ebA6102	ENOG4105C5H	ABC transporter
ebA6104	ENOG4105BZU	Histidine kinase
ebA6110	ENOG4105DP0	ferredoxin-NADP reductase
ebA6111	ENOG4105DUM	transcriptional regulator, lysR family
ebA6116	ENOG4107QZ7	Cellulose synthase catalytic subunit
ebA6124	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ebA6126	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
ebA6127	ENOG4105DB7	PHP domain protein
ebA6128	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
ebA6130	ENOG4108Z4T	Peptidase M50
ebA6131	ENOG4105C31	Tryptophanyl-tRNA synthetase
ebA6132	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
ebA6134	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
ebA6135	ENOG4105FE9	pseudouridine synthase
ebA6138	ENOG4105E4C	Lytic transglycosylase catalytic
ebA6142	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
ebA6149	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
ebA6155	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
ebA6156	ENOG41082UD	thioesterase Superfamily protein
ebA6159	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
ebA6160	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
ebA6162	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
ebA6165	ENOG4105K4H	Nlp p60 protein
ebA6171	ENOG4108Z0R	Transferase
ebA6174	ENOG4105D6S	protein involved in catabolism of external DNA
ebA6176	ENOG4105CJ3	phosphate transporter
ebA6179	ENOG4105EUJ	GTP cyclohydrolase i
ebA618	ENOG4105NQN	cytochrome C
ebA6181	ENOG4105E27	serine threonine protein kinase
ebA6183	ENOG4108VWS	Yaeq family
ebA6189	ENOG4105C37	(CBS) domain
ebA6190	ENOG4105C26	Dehydrogenase
ebA6197	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
ebA62	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
ebA6204	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
ebA6206	ENOG4108I5D	sulfate abc transporter
ebA6208	ENOG4108IJ6	ABC transporter
ebA621	ENOG41090Y2	cytochrome C
ebA6215	ENOG4105BZU	Histidine kinase
ebA6230	ENOG4105DA5	(ABC) transporter
ebA6231	ENOG4105E3A	(ABC) transporter
ebA6232	ENOG4108IUN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
ebA6233	ENOG4105DHQ	Histidine kinase
ebA6235	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
ebA6240	ENOG4105EMU	Dehydrogenase
ebA6242	ENOG4105CEY	Amp-dependent synthetase and ligase
ebA6247	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
ebA6248	ENOG4105D0S	secretion protein (HlyD
ebA6253	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
ebA6266	ENOG4108T0W	nitrous oxide maturation protein NosY
ebA6267	ENOG4105CIG	ABC transporter
ebA6268	ENOG4105DH4	Periplasmic copper-binding protein
ebA6270	ENOG4105HEE	Binding Domain protein
ebA6278	ENOG4105WH1	Two component transcriptional regulator luxr family
ebA6280	ENOG4105BZU	Histidine kinase
ebA6282	ENOG41076YT	nitrate reductase, gamma subunit
ebA6283	ENOG4105R3A	Nitrate reductase
ebA6285	ENOG4108IUE	nitrate reductase beta subunit
ebA6286	ENOG4105CRU	nitrate reductase, alpha subunit
ebA6291	ENOG4105FQT	
ebA6296	ENOG4105CBX	hi0933 family
ebA6309	ENOG4105CRQ	synthase (Component I)
ebA6313	ENOG4108UPT	UPF0178 protein
ebA6316	ENOG4107QI1	Mate efflux family protein
ebA6322	ENOG4105BZU	Histidine kinase
ebA6328	ENOG4105BZU	Histidine kinase
ebA633	ENOG4105F5W	AtP-binding protein
ebA6332	ENOG4105KAK	Plasmid pRiA4b ORF-3 family protein
ebA6347	ENOG4105F5W	AtP-binding protein
ebA6357	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
ebA6367	ENOG4105C9B	Cysteine desulfurase
ebA637	ENOG4105CFH	Aspartokinase
ebA6371	ENOG4108V1U	phospholipid-binding protein
ebA6375	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
ebA6378	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
ebA6380	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
ebA6384	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
ebA6386	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
ebA6387	ENOG4105CZX	twitching motility protein
ebA6388	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
ebA6395	ENOG4105WVQ	Fe-S assembly protein IscX
ebA6396	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
ebA6397	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
ebA64	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
ebA6400	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
ebA6401	ENOG4105C3J	Cysteine desulfurase
ebA6402	ENOG4105C3J	Cysteine desulfurase
ebA6404	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
ebA6405	ENOG4105D7W	serine acetyltransferase
ebA6410	ENOG4105ECY	inositol monophosphatase
ebA6422	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
ebA6426	ENOG4107QY8	reductase
ebA6435	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
ebA6439	ENOG4105BZU	Histidine kinase
ebA6441	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
ebA645	ENOG4105EGS	Mechanosensitive ion channel
ebA6453	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
ebA6456	ENOG4107RZZ	dna polymerase iii epsilon subunit
ebA6458	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
ebA6459	ENOG4105D1A	Methyltransferase
ebA6461	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
ebA6465	ENOG4105E9H	Lytic Murein transglycosylase
ebA6468	ENOG4108YZY	peptidylprolyl cis-trans isomerase
ebA6469	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ebA647	ENOG4105N82	Endonuclease
ebA6472	ENOG4105BZU	Histidine kinase
ebA6478	ENOG4105BZU	Histidine kinase
ebA6481	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
ebA6485	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
ebA6487	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
ebA6491	ENOG41080E2	ribosomal-protein-alanine acetyltransferase
ebA6494	ENOG41072GX	Peptidase M22 Glycoprotease
ebA6497	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
ebA6498	ENOG4105E0F	Histidine kinase
ebA6499	ENOG4105K9H	YciI-like protein
ebA6501	ENOG4107835	probably involved in intracellular septation (By similarity)
ebA6504	ENOG4107TF3	peptidylprolyl cis-trans isomerase
ebA6506	ENOG4105CSU	acyl-Coa dehydrogenase
ebA6510	ENOG4105C10	Electron transfer flavoprotein
ebA6511	ENOG4105BZJ	Electron transfer flavoprotein
ebA6513	ENOG4108IG5	Transcriptional regulator
ebA6514	ENOG4105EYA	deoxyribonuclease
ebA6518	ENOG4105CEY	Amp-dependent synthetase and ligase
ebA6523	ENOG4105DHJ	ABC, transporter
ebA6525	ENOG4105C9X	ppx gppa phosphatase
ebA6526	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
ebA6528	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
ebA6539	ENOG4107XID	2'-5' rna ligase
ebA6542	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
ebA6543	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
ebA6545	ENOG4107RA9	decarboxylase
ebA6546	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
ebA6549	ENOG41074MP	UPF0103 Mediator of ErbB2-driven cell motility-containing protein
ebA655	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
ebA6551	ENOG4105NBF	ammecr1 domain protein
ebA6555	ENOG4108JA2	transcriptioN-repair coupling factor
ebA658	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
ebA6583	ENOG4105ENA	helicase
ebA6589	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
ebA6594	ENOG4105FTC	Lytic transglycosylase catalytic
ebA661	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
ebA664	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
ebA6644	ENOG4105DFP	Integrase
ebA6645	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
ebA6647	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
ebA6652	ENOG4105VDB	UPF0125 protein
ebA6653	ENOG4108Z1B	Cyclase dehydrase
ebA6654	ENOG4105CNG	UPF0061 protein
ebA6655	ENOG4105DQE	DNA ligase
ebA6658	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
ebA666	ENOG4105C0D	helicase
ebA6661	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
ebA6664	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
ebA6665	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
ebA6667	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
ebA6671	ENOG4108ZAF	Molybdopterin
ebA6672	ENOG4105M00	molybdopterin converting factor, subunit 1
ebA6673	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
ebA6674	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
ebA6678	ENOG4105DVT	helicase
ebA6680	ENOG4107UX3	phosphatidylethanolamine N-methyltransferase
ebA6682	ENOG4105D6Z	AFG1 family ATPase
ebA6683	ENOG4107QN2	dihydrolipoyl dehydrogenase
ebA6684	ENOG4105C7S	Dehydrogenase
ebA6685	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
ebA6687	ENOG4105BZN	citrate synthase
ebA6689	ENOG4105E33	succinate dehydrogenase
ebA669	ENOG4107R3N	Filamentation induced by cAMP protein fic
ebA6693	ENOG4105FDP	GntR family transcriptional regulator
ebA6695	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
ebA670	ENOG4107QMH	DNA methylase
ebA6704	ENOG4105BZ1	(ABC) transporter
ebA6709	ENOG4105D8X	mechanosensitive ion channel
ebA6729	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
ebA6736	ENOG4105DNP	FAD linked oxidase domain protein
ebA6743	ENOG4105D0S	secretion protein (HlyD
ebA6744	ENOG4105CJ1	ABC, transporter
ebA6745	ENOG4105CMI	transporter
ebA6752	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
ebA6753	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
ebA6761	ENOG4105C01	Dihydroxy-acid dehydratase
ebA6770	ENOG4108RS6	transposase
ebA6773	ENOG4107QM5	aconitate hydratase
ebA6775	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
ebA6781	ENOG4105ESV	Glycosyl transferase, family 4
ebA6795	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
ebA6797	ENOG4107YJ4	chain length determinant protein
ebA6802	ENOG4108RB3	Capsular polysaccharide biosynthesis protein
ebA6806	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
ebA6809	ENOG4105FE1	phytoene synthase
ebA6810	ENOG4105FE1	phytoene synthase
ebA6811	ENOG4105CVN	desaturase
ebA6813	ENOG4108I0Y	(ABC) transporter
ebA6814	ENOG4108UJV	acyl-CoA thioesterase i
ebA6818	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
ebA6824	ENOG4105BZU	Histidine kinase
ebA6829	ENOG4105CD5	CoA-binding domain protein
ebA6834	ENOG4105BZM	domain protein
ebA6837	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
ebA6838	ENOG4107QMS	site-determining protein
ebA6839	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
ebA6841	ENOG4105CRK	lysyL-tRNA synthetase
ebA6842	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
ebA6850	ENOG4105WH1	Two component transcriptional regulator luxr family
ebA6855	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
ebA6861	ENOG4105ECP	epimerase
ebA6868	ENOG4105CEV	competence damage-inducible protein
ebA6869	ENOG4108JQ1	Dehydrogenase
ebA6876	ENOG4107SM8	Adenylate Guanylate cyclase
ebA6882	ENOG4108JJ7	ABC transporter
ebA6890	ENOG4105BZU	Histidine kinase
ebA6902	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
ebA6907	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
ebA6910	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
ebA6912	ENOG4105XA0	heptosyltransferase ii
ebA6917	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
ebA6918	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
ebA6920	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
ebA6921	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
ebA6926	ENOG4105EGS	Mechanosensitive ion channel
ebA6931	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
ebA6934	ENOG4108MJN	Glycosyl Transferase
ebA6940	ENOG4105YVM	Phosphoesterase, PA-phosphatase related
ebA6943	ENOG4108UQY	Iron-storage protein
ebA6946	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
ebA6958	ENOG4105CEP	NADH dehydrogenase
ebA6963	ENOG4107WSY	Domain of unknown function DUF20
ebA6964	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
ebA6968	ENOG4105W4M	Transport-associated protein
ebA697	ENOG4105E14	MotA TolQ exbB proton channel
ebA6974	ENOG4105D7Z	glutathione synthase
ebA698	ENOG4105FZW	flagellar biosynthesis regulator FlhF
ebA6991	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
ebA6999	ENOG41061N2	exported protein
ebA70	ENOG4105F5W	AtP-binding protein
ebA7001	ENOG4105CG3	alpha amylase, catalytic region
ebA7002	ENOG4107S9Q	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
ebA7003	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
ebA7008	ENOG41067HS	methyltransferase
ebA702	ENOG4105D7B	Flagellar biosynthesis protein flha
ebA7030	ENOG4105D5U	fad dependent oxidoreductase
ebA7034	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
ebA7036	ENOG4105D1H	recombination factor protein RarA
ebA7039	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
ebA7041	ENOG4105CNU	cell division protein FtsK
ebA7042	ENOG4105C3M	thioredoxin reductase
ebA7043	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
ebA7046	ENOG4108DG9	Smr protein MutS2
ebA7048	ENOG4108YZA	Nitrogen regulatory protein pii
ebA7049	ENOG4105C4K	Nad synthetase
ebA705	ENOG4105D00	flagellar biosynthetic protein flhB
ebA7053	ENOG4105F0N	pyrophosphate phospho-hydrolase
ebA7069	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
ebA7072	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
ebA7075	ENOG4105C2D	reductase
ebA7092	ENOG4108Z3N	Transcriptional regulator
ebA7097	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
ebA7101	ENOG4105BZS	acriflavin resistance protein
ebA7104	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
ebA7105	ENOG4105C02	permease
ebA7107	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
ebA7112	ENOG4105DJ0	Poly(A) Polymerase
ebA7113	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ebA7119	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
ebA7120	ENOG4107R03	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
ebA7121	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
ebA7122	ENOG4105CD8	aminopeptidase N
ebA713	ENOG4108R99	pseudouridine synthase
ebA7130	ENOG4105C7K	acetolactate synthase
ebA7132	ENOG4108ZP8	Acetolactate synthase small subunit
ebA7134	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
ebA7135	ENOG41071I4	Phosphatidylserine decarboxylase proenzyme
ebA7137	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
ebA7143	ENOG4105IFJ	Histidine kinase
ebA7146	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
ebA7148	ENOG4105VBA	Cytochrome
ebA715	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
ebA7152	ENOG4105E3J	oxidoreductase
ebA7154	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
ebA7157	ENOG4105CS1	NAD(P)H quinone oxidoreductase
ebA7158	ENOG4107S2Z	UPF0761 membrane protein
ebA7167	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
ebA7168	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
ebA7169	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
ebA7173	ENOG4108M8S	permease YjgP YjgQ family protein
ebA7174	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
ebA7181	ENOG4108JJ6	Type I secretion system ATPase
ebA7186	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
ebA7188	ENOG4105ERG	peptidase m48, ste24p
ebA7189	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
ebA7193	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
ebA7196	ENOG4105DHH	glycosyltransferase MGT family
ebA720	ENOG4105E39	Enoyl-CoA hydratase
ebA7202	ENOG4105EKQ	RNA-directed DNA polymerase
ebA722	ENOG4108UKI	Enoyl-CoA hydratase
ebA7220	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
ebA7225	ENOG4105C5H	ABC transporter
ebA723	ENOG4105CHR	reductase
ebA7261	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
ebA7267	ENOG4105NVB	glycoside hydrolase, family 19
ebA732	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
ebA736	ENOG4105C1G	acyl-Coa dehydrogenase
ebA744	ENOG4105CIZ	coA-substrate-specific enzyme activase
ebA748	ENOG4105DCU	2-hydroxyglutaryl-CoA dehydratase
ebA771	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
ebA773	ENOG4105GJM	(LipO)protein
ebA774	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
ebA776	ENOG4105CVE	Lytic murein transglycosylase
ebA778	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
ebA779	ENOG4108K5P	(LipO)protein
ebA781	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
ebA782	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
ebA788	ENOG4105F5W	AtP-binding protein
ebA790	ENOG4105BZU	Histidine kinase
ebA791	ENOG4105BZU	Histidine kinase
ebA793	ENOG4105BZU	Histidine kinase
ebA811	ENOG4105EJC	lysr family transcriptional regulator
ebA816	ENOG4105EJ9	Membrane
ebA819	ENOG4107QP3	malate synthase g
ebA829	ENOG4108HMX	isocitrate dehydrogenase (NADP)
ebA832	ENOG4105E9K	Isocitrate dehydrogenase
ebA835	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
ebA837	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
ebA838	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
ebA840	ENOG4105W5Q	DNA repair protein (RadC
ebA843	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ebA844	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
ebA864	ENOG4105BZU	Histidine kinase
ebA866	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
ebA867	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
ebA868	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
ebA870	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
ebA871	ENOG4105C22	threonyL-tRNA synthetase
ebA872	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
ebA875	ENOG4105E0X	reductase
ebA878	ENOG4108UMR	transcriptional regulator AsnC family
ebA885	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
ebA888	ENOG4105F64	nitrite reductase
ebA896	ENOG4105C6T	cysteine synthase
ebA899	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
ebA900	ENOG4105CFV	Tetratricopeptide repeat protein
ebA902	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
ebA903	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
ebA904	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
ebA907	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
ebA909	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
ebA911	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
ebA913	ENOG4105UYK	outer membrane protein a
ebA914	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
ebA931	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
ebA932	ENOG4105DR5	peptidase
ebA935	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
ebA937	ENOG4108UJD	30S ribosomal protein S9
ebA938	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
ebA942	ENOG4108S0N	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol (By similarity)
ebA950	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
ebA951	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
ebA955	ENOG4105E4C	Lytic transglycosylase catalytic
ebA960	ENOG4107WP9	Histidine kinase
ebA966	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
ebA969	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
ebA977	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
ebA986	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
ebA993	ENOG4105CM2	brancheD-chain amino acid aminotransferase
ebA996	ENOG4107QKV	phosphomannomutase
ebA999	ENOG4105BZU	Histidine kinase
ebB103	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
ebB104	ENOG4108UK5	Transposase
ebB108	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
ebB113	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
ebB115	ENOG41062QD	Membrane
ebB116	ENOG4105K70	DNA-binding protein
ebB123	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
ebB124	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
ebB125	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
ebB126	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
ebB127	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
ebB128	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
ebB129	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
ebB130	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
ebB131	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
ebB132	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ebB133	ENOG4108ZT0	50S ribosomal protein l17
ebB142	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
ebB143	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
ebB144	ENOG4107Z67	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
ebB145	ENOG4105X96	Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Activated D-alanyl-Dcp donates its D-alanyl substituent to membrane-associated LTA (By similarity)
ebB15	ENOG4108ZE9	Monovalent cation H antiporter subunit C
ebB150	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
ebB154	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
ebB155	ENOG4108Z4U	Ferredoxin
ebB157	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
ebB158	ENOG4108VBZ	doxx family
ebB161	ENOG4105K63	Thioredoxin
ebB162	ENOG4105M71	acetolactate synthase 1 regulatory subunit
ebB163	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
ebB164	ENOG4105E96	Colicin v production protein
ebB166	ENOG41086DT	Membrane protein of unknown function
ebB167	ENOG41090R7	Ferric uptake
ebB168	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
ebB17	ENOG4105M0J	Toxic component of a toxin-antitoxin (TA) module. A
ebB170	ENOG4108VAU	general secretion pathway protein G
ebB173	ENOG41085FC	arsR family transcriptional regulator
ebB176	ENOG4109015	Biopolymer transport protein exbD tolR
ebB177	ENOG41082GY	Binds directly to 16S ribosomal RNA (By similarity)
ebB180	ENOG4108YY7	Invasion gene expression up-regulator SirB
ebB196	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
ebB202	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ebB205	ENOG4107M1U	Histone family protein nucleoid-structuring protein H-NS
ebB206	ENOG4107M1U	Histone family protein nucleoid-structuring protein H-NS
ebB208	ENOG4107M1U	Histone family protein nucleoid-structuring protein H-NS
ebB211	ENOG4107M1U	Histone family protein nucleoid-structuring protein H-NS
ebB213	ENOG4105WKW	Pfam:DUF1458
ebB214	ENOG4105XUA	cytochrome c
ebB217	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
ebB22	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
ebB229	ENOG4108ZIT	Ferredoxin, 2FE-2S
ebB230	ENOG4108Z4V	iron-sulfur cluster assembly
ebB233	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
ebB238	ENOG4108302	MgtC SapB transporter
ebB247	ENOG4105K5M	30s ribosomal protein S16
ebB25	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
ebB253	ENOG4105W7J	DNA binding
ebB30	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
ebB31	ENOG4108UKZ	OsmC family
ebB33	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
ebB35	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
ebB37	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
ebB39	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
ebB40	ENOG4105VIE	preprotein translocase, subunit YajC
ebB42	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
ebB43	ENOG4108V6E	Cell division protein mraZ
ebB45	ENOG4108VAU	general secretion pathway protein G
ebB48	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
ebB49	ENOG4108UNF	response regulator
ebB5	ENOG41090A4	Pterin carbinolamine dehydratase
ebB50	ENOG4105M3Z	response regulator
ebB6	ENOG4108VKQ	nitriC oxide reductase
ebB66	ENOG4105KME	endoribonuclease L-psp
ebB67	ENOG4107MBT	Plasmid stabilisation system protein
ebB74	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
ebB82	ENOG41082AG	Plasmid maintenance system antidote protein
ebB83	ENOG41061N2	exported protein
ebB84	ENOG4107YD3	Thioesterase
ebB86	ENOG4105W2W	Cytotoxic translational repressor of toxin-antitoxin stability system
ebB89	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
ebB9	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
ebB90	ENOG4105X5M	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
ebB91	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
ebB95	ENOG4108YZA	Nitrogen regulatory protein pii
ebC1	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
ebC10	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
ebC12	ENOG4105VEQ	Cold shock protein
ebC14	ENOG4105I7I	quinohemoprotein amine dehydrogenase gamma subunit
ebC15	ENOG4107EJC	Preprotein translocase subunit SecG
ebC2	ENOG4105K46	50S ribosomal protein l27
ebC3	ENOG41084PQ	50s ribosomal protein l29
ebC4	ENOG4105VPB	50S ribosomal protein L30
ebC5	ENOG4105VGS	50s ribosomal protein l32
ebC6	ENOG4105W0E	50S ribosomal protein L33
ebC8	ENOG4105VJV	50s ribosomal protein L35
ebC9	ENOG41067V7	50S ribosomal protein L36
ebD1	ENOG4107RU9	Transcriptional regulator, Crp Fnr family
ebD103	ENOG41084HI	prevent-host-death family
ebD108	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
ebD109	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
ebD11	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
ebD115	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
ebD116	ENOG4108RS6	transposase
ebD12	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
ebD14	ENOG4105VUH	addiction module killer protein
ebD15	ENOG4105YES	addiction module antidote protein
ebD2	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
ebD28	ENOG4105XMH	SpoVT AbrB domain protein
ebD36	ENOG4105M0J	Toxic component of a toxin-antitoxin (TA) module. A
ebD4	ENOG4105DB1	molybdopterin oxidoreductase
ebD48	ENOG4105UKP	Protein of unknown function (DUF1778)
ebD68	ENOG41080Z8	PHOSPHOCARRIER protein
ebD7	ENOG41080XP	Cbs domain
ebD70	ENOG4108Z43	UPF0250 protein
ebD71	ENOG4105DFH	Transport of potassium into the cell (By similarity)
ebD72	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
ebD83	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
ebD86	ENOG4105NBK	UPF0345 protein
ebD89	ENOG4105DU1	integral membrane protein, terc
ebD98	ENOG410600T	transposase
p1B119	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
p1B137	ENOG4105UKP	Protein of unknown function (DUF1778)
p1B143	ENOG4107WCQ	Anion-transporting ATPase
p1B145	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
p1B164	ENOG4105F37	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
p1B167	ENOG4107QHF	type ii secretion system protein e
p1B177	ENOG4105T95	Thiol disulfide interChange protein
p1B201	ENOG4105KK6	nuclease
p1B237	ENOG4105DH7	May be involved in recombination (By similarity)
p1B254	ENOG4105VK3	rdd domain containing protein
p1B257	ENOG4105CDU	Replicative dna helicase
p1B299	ENOG4108MN8	Membrane
p1B306	ENOG4105DAX	Pfam:DUF2983
p1B319	ENOG4108ZAI	phosphatidylglycerophosphatase a
p1B324	ENOG4108M24	von Willebrand factor, type A
p1B347	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
p1B362	ENOG4105BZU	Histidine kinase
p1B53	ENOG4105CB5	ATP-dependent DNA helicase recG
p1B79	ENOG4105FA0	parb-like partition protein
p2A104	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
p2A109	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
p2A120	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
p2A122	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
p2A13	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
p2A133	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
p2A16	ENOG4105DQU	oxidoreductase, subunit beta
p2A162	ENOG4105VFQ	Histone family protein nucleoid-structuring protein H-NS
p2A176	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
p2A177	ENOG4105F5W	AtP-binding protein
p2A184	ENOG4105VU5	Resolvase domain-containing protein
p2A2	ENOG4105DAB	fumarate reductase succinate dehydrogenase flavoprotein domain protein
p2A206	ENOG4105CS1	NAD(P)H quinone oxidoreductase
p2A219	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
p2A243	ENOG4105KT5	UmuD protein
p2A244	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
p2A268	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
p2A308	ENOG4105VU5	Resolvase domain-containing protein
p2A315	ENOG4105F5W	AtP-binding protein
p2A323	ENOG4105DAB	fumarate reductase succinate dehydrogenase flavoprotein domain protein
p2A325	ENOG4105F2I	Transposase
p2A326	ENOG4105F2I	Transposase
p2A332	ENOG4105CHR	reductase
p2A334	ENOG4105CB2	alcohol dehydrogenase
p2A341	ENOG4105E39	Enoyl-CoA hydratase
p2A342	ENOG4105ME0	Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor (By similarity)
p2A344	ENOG4105EIH	LPPG Fo 2-phospho-L-lactate transferase
p2A347	ENOG41088YA	Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives (By similarity)
p2A350	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
p2A358	ENOG4107YCY	Transcriptional regulator
p2A373	ENOG4105CHR	reductase
p2A379	ENOG4105CPC	Aldo Keto reductase
p2A380	ENOG4105C1G	acyl-Coa dehydrogenase
p2A386	ENOG4105CEY	Amp-dependent synthetase and ligase
p2A389	ENOG4105E39	Enoyl-CoA hydratase
p2A392	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
p2A394	ENOG4105CHU	acetyl-coa acetyltransferase
p2A408	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
p2A409	ENOG4105CHU	acetyl-coa acetyltransferase
p2A45	ENOG4107SCJ	type I restriction enzyme EcoKI subunit R
p2A50	ENOG4107XZC	Restriction modification system DNA (Specificity
p2A58	ENOG4105CMI	transporter
p2A60	ENOG41086KC	Transcriptional regulator
p2A7	ENOG4105X7H	acyl-CoA dehydrogenase
p2A9	ENOG4105C1G	acyl-Coa dehydrogenase
p2B17	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)