locus-tag	class	description
pbN1_00010	COG1028	Short-chain dehydrogenase reductase Sdr
pbN1_00050	COG0243	molybdopterin cofactor binding
pbN1_00080	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
pbN1_00100	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
pbN1_00110	COG0145	ligase activity
pbN1_00120	COG4647	ligase activity
pbN1_00130	COG0145	ligase activity
pbN1_00260	COG4977	sequence-specific DNA binding
pbN1_00260	COG1917	Cupin 2, conserved barrel domain protein
pbN1_00400	COG0163	prenyltransferase activity
pbN1_00420	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
pbN1_00430	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
pbN1_00460	COG0776	regulation of translation
pbN1_00490	COG4804	nuclease activity
pbN1_00540	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
pbN1_00610	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
pbN1_00850	COG1192	Involved in chromosome partitioning
pbN1_01170	COG2003	Belongs to the UPF0758 family
pbN1_01180	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
pbN1_01220	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
pbN1_01230	COG1185	polyribonucleotide nucleotidyltransferase activity
pbN1_01240	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
pbN1_01250	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
pbN1_01260	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
pbN1_01270	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
pbN1_01280	COG0195	Participates in both transcription termination and antitermination
pbN1_01280	COG2251	uridine kinase activity
pbN1_01290	COG0779	Required for maturation of 30S ribosomal subunits
pbN1_01300	COG0446	pyridine nucleotide-disulphide oxidoreductase
pbN1_01300	COG1902	pentaerythritol trinitrate reductase activity
pbN1_01310	COG1028	Short-chain dehydrogenase reductase Sdr
pbN1_01340	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
pbN1_01360	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
pbN1_01390	COG5433	transposase activity
pbN1_01450	COG1136	(ABC) transporter
pbN1_01500	COG3047	cAMP biosynthetic process
pbN1_01510	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
pbN1_01520	COG1704	LemA family
pbN1_01550	COG1611	Belongs to the LOG family
pbN1_01570	COG2986	histidine ammonia-lyase
pbN1_01580	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
pbN1_01590	COG1228	amidohydrolase
pbN1_01600	COG0010	Belongs to the arginase family
pbN1_01610	COG0513	Belongs to the DEAD box helicase family
pbN1_01640	COG1960	acyl-CoA dehydrogenase activity
pbN1_01650	COG1024	Enoyl-CoA hydratase
pbN1_01650	COG1250	3-hydroxyacyl-CoA dehydrogenase
pbN1_01660	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
pbN1_01670	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
pbN1_01680	COG2855	membrane
pbN1_01760	COG0318	PFAM AMP-dependent synthetase and ligase
pbN1_01880	COG2175	clavaminate synthase activity
pbN1_01890	COG3246	L-lysine catabolic process to acetate
pbN1_01930	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
pbN1_01940	COG0573	inorganic phosphate transmembrane transporter activity
pbN1_01950	COG0573	inorganic phosphate transmembrane transporter activity
pbN1_01970	COG2226	methyltransferase
pbN1_02060	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
pbN1_02140	COG1595	DNA-templated transcription, initiation
pbN1_02200	COG2391	methyltransferase activity
pbN1_02220	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
pbN1_02230	COG2855	membrane
pbN1_02300	COG2197	response regulator
pbN1_02320	COG0840	transmembrane signaling receptor activity
pbN1_02350	COG2425	protein containing a von Willebrand factor type A (vWA) domain
pbN1_02360	COG0674	pyruvate-flavodoxin oxidoreductase activity
pbN1_02360	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
pbN1_02370	COG0318	PFAM AMP-dependent synthetase and ligase
pbN1_02390	COG2197	response regulator
pbN1_02400	COG0183	Belongs to the thiolase family
pbN1_02410	COG1607	acyl-coa hydrolase
pbN1_02420	COG1024	Enoyl-CoA hydratase
pbN1_02420	COG1250	3-hydroxyacyl-CoA dehydrogenase
pbN1_02430	COG0243	molybdopterin cofactor binding
pbN1_02450	COG1924	4 iron, 4 sulfur cluster binding
pbN1_02480	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
pbN1_02520	COG1960	acyl-CoA dehydrogenase activity
pbN1_02530	COG1028	Short-chain dehydrogenase reductase Sdr
pbN1_02560	COG4221	oxidoreductase activity
pbN1_02560	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
pbN1_02560	COG0300	oxidoreductase activity
pbN1_02560	COG3321	synthase
pbN1_02570	COG0318	PFAM AMP-dependent synthetase and ligase
pbN1_02630	COG1013	pyruvate-flavodoxin oxidoreductase activity
pbN1_02640	COG0674	pyruvate-flavodoxin oxidoreductase activity
pbN1_02640	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
pbN1_02650	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
pbN1_02700	COG4372	Transposase
pbN1_02840	COG1012	belongs to the aldehyde dehydrogenase family
pbN1_02850	COG0583	DNA-binding transcription factor activity
pbN1_02860	COG1012	belongs to the aldehyde dehydrogenase family
pbN1_02890	COG1804	L-carnitine dehydratase bile acid-inducible protein F
pbN1_02910	COG1024	Enoyl-CoA hydratase
pbN1_02930	COG0183	Belongs to the thiolase family
pbN1_02950	COG1028	Short-chain dehydrogenase reductase Sdr
pbN1_02980	COG0322	excinuclease ABC activity
pbN1_02990	COG1472	Belongs to the glycosyl hydrolase 3 family
pbN1_03000	COG0736	holo-[acyl-carrier-protein] synthase activity
pbN1_03010	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
pbN1_03020	COG1381	Involved in DNA repair and RecF pathway recombination
pbN1_03030	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
pbN1_03040	COG0571	ribonuclease III activity
pbN1_03060	COG0681	Belongs to the peptidase S26 family
pbN1_03070	COG0481	GTPase activity
pbN1_03090	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
pbN1_03140	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
pbN1_03170	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
pbN1_03200	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
pbN1_03210	COG0416	fatty acid biosynthetic process
pbN1_03220	COG0333	Belongs to the bacterial ribosomal protein bL32 family
pbN1_03240	COG0424	maF-like protein
pbN1_03250	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
pbN1_03270	COG0546	phosphoglycolate phosphatase activity
pbN1_03290	COG1530	ribonuclease E activity
pbN1_03300	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
pbN1_03310	COG0556	nucleotide-excision repair
pbN1_03360	COG1067	ATP-dependent peptidase activity
pbN1_03380	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
pbN1_03410	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
pbN1_03420	COG1473	amidohydrolase
pbN1_03430	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
pbN1_03450	COG0084	hydrolase, TatD family'
pbN1_03480	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
pbN1_03490	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
pbN1_03530	COG1376	ErfK ybiS ycfS ynhG family protein
pbN1_03670	COG0243	molybdopterin cofactor binding
pbN1_03680	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
pbN1_03690	COG3327	negative regulation of DNA-templated transcription, initiation
pbN1_03700	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
pbN1_03710	COG1846	Transcriptional regulator
pbN1_03720	COG1012	belongs to the aldehyde dehydrogenase family
pbN1_03790	COG2204	response regulator
pbN1_03800	COG2204	response regulator
pbN1_03850	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
pbN1_03880	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
pbN1_03900	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
pbN1_04000	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
pbN1_04000	COG0574	Belongs to the PEP-utilizing enzyme family
pbN1_04040	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
pbN1_04060	COG1960	acyl-CoA dehydrogenase activity
pbN1_04080	COG0183	Belongs to the thiolase family
pbN1_04090	COG1024	Enoyl-CoA hydratase
pbN1_04100	COG0318	PFAM AMP-dependent synthetase and ligase
pbN1_04140	COG4584	PFAM Integrase catalytic
pbN1_04160	COG1309	transcriptional regulator
pbN1_04170	COG2814	Major facilitator Superfamily
pbN1_04190	COG0411	ABC transporter
pbN1_04240	COG1028	Short-chain dehydrogenase reductase Sdr
pbN1_04250	COG1024	Enoyl-CoA hydratase
pbN1_04380	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
pbN1_04410	COG1363	Peptidase, m42
pbN1_04420	COG0189	ligase activity
pbN1_04420	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
pbN1_04430	COG0367	asparagine synthase
pbN1_04440	COG0861	Integral membrane protein TerC family
pbN1_04480	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
pbN1_04490	COG3012	SEC-C Motif Domain Protein
pbN1_04550	COG3012	SEC-C Motif Domain Protein
pbN1_04550	COG3318	Belongs to the UPF0149 family
pbN1_04560	COG0220	tRNA (guanine-N7-)-methyltransferase activity
pbN1_04580	COG0254	rRNA binding
pbN1_04600	COG0166	Belongs to the GPI family
pbN1_04610	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
pbN1_04620	COG0501	Belongs to the peptidase M48B family
pbN1_04630	COG1162	GTPase activity
pbN1_04640	COG0183	Belongs to the thiolase family
pbN1_04650	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
pbN1_04670	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
pbN1_04690	COG0826	peptidase U32
pbN1_04720	COG1132	(ABC) transporter
pbN1_04790	COG2409	Drug exporters of the RND superfamily
pbN1_04870	COG2217	Heavy metal translocating P-type atpase
pbN1_04890	COG0635	Involved in the biosynthesis of porphyrin-containing compound
pbN1_04900	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
pbN1_04940	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
pbN1_04950	COG3243	poly(R)-hydroxyalkanoic acid synthase
pbN1_04960	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
pbN1_05010	COG2010	Cytochrome c
pbN1_05040	COG3278	Belongs to the heme-copper respiratory oxidase family
pbN1_05060	COG2217	Heavy metal translocating P-type atpase
pbN1_05080	COG0494	nUDIX hydrolase
pbN1_05110	COG0745	RESPONSE REGULATOR receiver
pbN1_05110	COG2972	Histidine kinase
pbN1_05190	COG1666	GTP binding
pbN1_05200	COG3123	guanosine phosphorylase activity
pbN1_05220	COG0137	argininosuccinate synthase activity
pbN1_05230	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
pbN1_05240	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
pbN1_05260	COG0268	Binds directly to 16S ribosomal RNA
pbN1_05300	COG0563	adenylate kinase activity
pbN1_05310	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
pbN1_05320	COG2835	tetraacyldisaccharide 4'-kinase activity
pbN1_05330	COG1663	tetraacyldisaccharide 4'-kinase activity
pbN1_05340	COG0848	biopolymer transport protein
pbN1_05350	COG0811	peptide transport
pbN1_05360	COG1570	exodeoxyribonuclease VII activity
pbN1_05370	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
pbN1_05410	COG0820	rRNA (adenine-C2-)-methyltransferase activity
pbN1_05460	COG1538	Outer membrane efflux protein
pbN1_05570	COG2353	YceI-like domain
pbN1_05590	COG3038	cytochrome b561
pbN1_05600	COG0702	epimerase
pbN1_05620	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
pbN1_05690	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
pbN1_05700	COG2414	aldehyde ferredoxin oxidoreductase
pbN1_05770	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
pbN1_05780	COG0243	molybdopterin cofactor binding
pbN1_05780	COG0243	molybdopterin cofactor binding
pbN1_05810	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
pbN1_05850	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
pbN1_05890	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
pbN1_05900	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
pbN1_05910	COG0740	serine-type endopeptidase activity
pbN1_05920	COG0544	peptidyl-prolyl cis-trans isomerase activity
pbN1_05930	COG2766	serine protein kinase
pbN1_05940	COG2718	Belongs to the UPF0229 family
pbN1_05950	COG2719	SpoVR family
pbN1_05960	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
pbN1_05960	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
pbN1_06040	COG3290	protein histidine kinase activity
pbN1_06040	COG0840	transmembrane signaling receptor activity
pbN1_06070	COG0436	Aminotransferase
pbN1_06090	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
pbN1_06100	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
pbN1_06130	COG0791	NLP P60 protein
pbN1_06150	COG1840	ABC-type Fe3 transport system, periplasmic component
pbN1_06300	COG1178	ABC-type Fe3 transport system permease component
pbN1_06310	COG3842	ATPase activity
pbN1_06320	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
pbN1_06330	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
pbN1_06340	COG0167	dihydroorotate dehydrogenase activity
pbN1_06350	COG4657	Part of a membrane complex involved in electron transport
pbN1_06360	COG2878	Part of a membrane complex involved in electron transport
pbN1_06370	COG4656	Part of a membrane complex involved in electron transport
pbN1_06380	COG4658	electron transport chain
pbN1_06410	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
pbN1_06450	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
pbN1_06500	COG0326	Molecular chaperone. Has ATPase activity
pbN1_06520	COG2951	lytic endotransglycosylase activity
pbN1_06590	COG1230	cation diffusion facilitator family transporter
pbN1_06620	COG1007	ATP synthesis coupled electron transport
pbN1_06650	COG0713	ATP synthesis coupled electron transport
pbN1_06670	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
pbN1_06680	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
pbN1_06690	COG1034	ATP synthesis coupled electron transport
pbN1_06690	COG1034	ATP synthesis coupled electron transport
pbN1_06710	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
pbN1_06720	COG0649	NAD binding
pbN1_06730	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
pbN1_06740	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
pbN1_06750	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
pbN1_06770	COG0149	triose-phosphate isomerase activity
pbN1_06780	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
pbN1_06790	COG0573	inorganic phosphate transmembrane transporter activity
pbN1_06800	COG0573	inorganic phosphate transmembrane transporter activity
pbN1_06810	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
pbN1_06820	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
pbN1_06840	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
pbN1_06850	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
pbN1_06860	COG1534	Rna-binding protein
pbN1_06880	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
pbN1_06890	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
pbN1_06900	COG0505	Belongs to the CarA family
pbN1_06910	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
pbN1_06920	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
pbN1_06930	COG0735	belongs to the Fur family
pbN1_06940	COG0497	DNA recombination
pbN1_06950	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
pbN1_06960	COG1420	regulation of RNA biosynthetic process
pbN1_06970	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
pbN1_06980	COG0515	serine threonine protein kinase
pbN1_06980	COG2815	serine threonine protein kinase
pbN1_06990	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
pbN1_07000	COG0443	Heat shock 70 kDa protein
pbN1_07010	COG0484	heat shock protein binding
pbN1_07020	COG0215	cysteine-tRNA ligase activity
pbN1_07050	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
pbN1_07060	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
pbN1_07100	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
pbN1_07110	COG0285	dihydrofolate synthase activity
pbN1_07120	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
pbN1_07130	COG0159	tryptophan synthase activity
pbN1_07140	COG0133	tryptophan synthase activity
pbN1_07150	COG0135	phosphoribosylanthranilate isomerase activity
pbN1_07160	COG0101	tRNA pseudouridine synthase activity
pbN1_07190	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
pbN1_07200	COG0473	3-isopropylmalate dehydrogenase activity
pbN1_07210	COG0066	3-isopropylmalate dehydratase activity
pbN1_07220	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
pbN1_07240	COG2814	Major facilitator Superfamily
pbN1_07250	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
pbN1_07260	COG0440	acetolactate synthase activity
pbN1_07270	COG0028	Belongs to the TPP enzyme family
pbN1_07280	COG0318	PFAM AMP-dependent synthetase and ligase
pbN1_07310	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
pbN1_07330	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
pbN1_07340	COG3344	reverse transcriptase
pbN1_07350	COG1250	3-hydroxyacyl-CoA dehydrogenase
pbN1_07360	COG0277	FAD linked oxidase domain protein
pbN1_07370	COG1752	Esterase of the alpha-beta hydrolase superfamily
pbN1_07380	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
pbN1_07390	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
pbN1_07410	COG1028	Short-chain dehydrogenase reductase Sdr
pbN1_07420	COG3243	poly(R)-hydroxyalkanoic acid synthase
pbN1_07440	COG0564	pseudouridine synthase activity
pbN1_07510	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
pbN1_07560	COG4647	ligase activity
pbN1_07570	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
pbN1_07580	COG0145	ligase activity
pbN1_07670	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
pbN1_07680	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
pbN1_07700	COG0643	Histidine kinase
pbN1_07700	COG0784	Response regulator, receiver
pbN1_07700	COG2198	Histidine kinase
pbN1_07710	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
pbN1_07720	COG0745	RESPONSE REGULATOR receiver
pbN1_07730	COG0784	Response regulator, receiver
pbN1_07730	COG0835	chemotaxis
pbN1_07740	COG0784	Response regulator, receiver
pbN1_07740	COG0835	chemotaxis
pbN1_07750	COG2201	protein-glutamate methylesterase activity
pbN1_07770	COG1360	Flagellar Motor Protein
pbN1_07780	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
pbN1_07830	COG0402	S-adenosylhomocysteine deaminase activity
pbN1_07840	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
pbN1_07870	COG0318	PFAM AMP-dependent synthetase and ligase
pbN1_07890	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
pbN1_07900	COG1960	acyl-CoA dehydrogenase activity
pbN1_07940	COG2059	Chromate
pbN1_07950	COG2259	Doxx family
pbN1_07960	COG1271	oxidase subunit
pbN1_07970	COG1294	oxidase, subunit
pbN1_07990	COG3447	MASE1 domain protein
pbN1_07990	COG5001	Diguanylate cyclase
pbN1_07990	COG5002	protein histidine kinase activity
pbN1_08000	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
pbN1_08040	COG3622	Belongs to the hyi family
pbN1_08060	COG3193	protein, possibly involved in utilization of glycolate and propanediol
pbN1_08080	COG0438	transferase activity, transferring glycosyl groups
pbN1_08080	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
pbN1_08090	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
pbN1_08100	COG0697	spore germination
pbN1_08110	COG0004	ammonium transporteR
pbN1_08220	COG0626	cystathionine gamma-synthase activity
pbN1_08250	COG0517	IMP dehydrogenase activity
pbN1_08260	COG1013	pyruvate-flavodoxin oxidoreductase activity
pbN1_08270	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
pbN1_08270	COG0674	pyruvate-flavodoxin oxidoreductase activity
pbN1_08320	COG4263	nitrous-oxide reductase activity
pbN1_08330	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
pbN1_08350	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
pbN1_08360	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
pbN1_08380	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
pbN1_08390	COG2009	succinate dehydrogenase
pbN1_08400	COG0516	GMP reductase activity
pbN1_08400	COG0517	IMP dehydrogenase activity
pbN1_08410	COG1126	abc transporter atp-binding protein
pbN1_08420	COG0765	amino acid transport
pbN1_08430	COG0765	amino acid transport
pbN1_08440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
pbN1_08660	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
pbN1_08670	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
pbN1_08700	COG1677	Flagellar hook-basal body complex protein FliE
pbN1_08740	COG1766	The M ring may be actively involved in energy transduction
pbN1_08770	COG1157	protein secretion by the type III secretion system
pbN1_08820	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
pbN1_08840	COG1338	Plays a role in the flagellum-specific transport system
pbN1_08880	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
pbN1_08910	COG1706	bacterial-type flagellum-dependent cell motility
pbN1_08920	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
pbN1_08940	COG4787	bacterial-type flagellum-dependent cell motility
pbN1_08960	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
pbN1_08970	COG1558	bacterial-type flagellum-dependent cell motility
pbN1_08980	COG1815	bacterial-type flagellum-dependent cell motility
pbN1_09060	COG1595	DNA-templated transcription, initiation
pbN1_09100	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
pbN1_09110	COG0739	heme binding
pbN1_09120	COG0316	Belongs to the HesB IscA family
pbN1_09130	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
pbN1_09140	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
pbN1_09150	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
pbN1_09160	COG1765	OsmC-like protein
pbN1_09170	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
pbN1_09230	COG0494	nUDIX hydrolase
pbN1_09240	COG0442	prolyl-tRNA aminoacylation
pbN1_09250	COG0741	lytic transglycosylase activity
pbN1_09290	COG2205	protein histidine kinase activity
pbN1_09310	COG2204	response regulator
pbN1_09330	COG0312	modulator of DNA gyrase
pbN1_09360	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
pbN1_09410	COG0482	sulfurtransferase activity
pbN1_09490	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
pbN1_09500	COG2096	Adenosyltransferase
pbN1_09510	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
pbN1_09520	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
pbN1_09530	COG0521	Mo-molybdopterin cofactor biosynthetic process
pbN1_09540	COG3028	Belongs to the UPF0307 family
pbN1_09550	COG0312	modulator of DNA gyrase
pbN1_09560	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
pbN1_09570	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
pbN1_09580	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
pbN1_09590	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
pbN1_09610	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
pbN1_09620	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
pbN1_09630	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
pbN1_09630	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
pbN1_09640	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
pbN1_09660	COG0793	Belongs to the peptidase S41A family
pbN1_09680	COG0588	phosphoglycerate mutase activity
pbN1_09700	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
pbN1_09720	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
pbN1_09740	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
pbN1_09750	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
pbN1_09760	COG1040	competence protein
pbN1_09770	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
pbN1_09780	COG2226	methyltransferase
pbN1_09810	COG0218	Necessary for normal cell division and for the maintenance of normal septation
pbN1_09840	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
pbN1_09860	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
pbN1_09870	COG5001	Diguanylate cyclase
pbN1_09870	COG5002	protein histidine kinase activity
pbN1_09870	COG3447	MASE1 domain protein
pbN1_09880	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
pbN1_09880	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
pbN1_09900	COG1385	rRNA (uridine-N3-)-methyltransferase activity
pbN1_09920	COG0483	inositol monophosphate 1-phosphatase activity
pbN1_09930	COG3954	Phosphoribulokinase
pbN1_09940	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
pbN1_09950	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
pbN1_09960	COG0126	phosphoglycerate kinase activity
pbN1_09980	COG0469	pyruvate kinase activity
pbN1_10040	COG5001	Diguanylate cyclase
pbN1_10040	COG5002	protein histidine kinase activity
pbN1_10050	COG0675	Transposase, IS605 OrfB family
pbN1_10080	COG2885	chlorophyll binding
pbN1_10100	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
pbN1_10190	COG1484	DNA-dependent DNA replication
pbN1_10280	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
pbN1_10300	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
pbN1_10310	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
pbN1_10320	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
pbN1_10330	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
pbN1_10350	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
pbN1_10360	COG0006	proline dipeptidase activity
pbN1_10370	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
pbN1_10380	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
pbN1_10390	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
pbN1_10400	COG0138	bifunctional purine biosynthesis protein purh
pbN1_10410	COG0151	Belongs to the GarS family
pbN1_10420	COG0408	coproporphyrinogen oxidase activity
pbN1_10440	COG2959	enzyme of heme biosynthesis
pbN1_10460	COG0181	hydroxymethylbilane synthase activity
pbN1_10470	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
pbN1_10490	COG0165	Argininosuccinate lyase
pbN1_10500	COG0515	serine threonine protein kinase
pbN1_10500	COG2815	serine threonine protein kinase
pbN1_10510	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
pbN1_10530	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
pbN1_10540	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
pbN1_10550	COG0642	Histidine kinase
pbN1_10570	COG0459	protein refolding
pbN1_10580	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
pbN1_10600	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
pbN1_10610	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
pbN1_10620	COG2969	positive regulation of protein catabolic process
pbN1_10630	COG0625	glutathione transferase activity
pbN1_10640	COG2857	Cytochrome c1
pbN1_10650	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
pbN1_10660	COG0723	plastoquinol--plastocyanin reductase activity
pbN1_10670	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
pbN1_10680	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
pbN1_10690	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
pbN1_10700	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
pbN1_10730	COG0243	molybdopterin cofactor binding
pbN1_10750	COG2223	nitrite transmembrane transporter activity
pbN1_10770	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
pbN1_10820	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
pbN1_10830	COG0557	exoribonuclease II activity
pbN1_10840	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
pbN1_10850	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
pbN1_10870	COG0330	HflC and HflK could
pbN1_10880	COG0330	HflC and HflK could
pbN1_10890	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
pbN1_10900	COG1923	regulation of RNA biosynthetic process
pbN1_10910	COG1160	GTP binding
pbN1_10920	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
pbN1_10930	COG2976	Protein conserved in bacteria
pbN1_10940	COG0124	histidyl-tRNA synthetase
pbN1_10950	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
pbN1_10960	COG1426	Protein conserved in bacteria
pbN1_10980	COG0820	rRNA (adenine-C2-)-methyltransferase activity
pbN1_10990	COG0105	UTP biosynthetic process
pbN1_11000	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
pbN1_11010	COG0045	succinate-CoA ligase (ADP-forming) activity
pbN1_11040	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
pbN1_11060	COG0805	protein transport
pbN1_11070	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
pbN1_11080	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
pbN1_11100	COG0140	phosphoribosyl-ATP diphosphatase activity
pbN1_11110	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
pbN1_11120	COG0107	imidazoleglycerol-phosphate synthase activity
pbN1_11130	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
pbN1_11140	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
pbN1_11150	COG0131	Imidazoleglycerol-phosphate dehydratase
pbN1_11160	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
pbN1_11170	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
pbN1_11180	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
pbN1_11190	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
pbN1_11200	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
pbN1_11220	COG0842	Transport permease protein
pbN1_11230	COG1131	(ABC) transporter
pbN1_11260	COG2853	Lipoprotein
pbN1_11270	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
pbN1_11280	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
pbN1_11290	COG1127	ABC transporter
pbN1_11320	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
pbN1_11340	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
pbN1_11350	COG1024	Enoyl-CoA hydratase
pbN1_11370	COG0204	Acyl-transferase
pbN1_11380	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
pbN1_11390	COG0751	glycine-tRNA ligase activity
pbN1_11400	COG0752	glycyl-tRNA synthetase alpha subunit
pbN1_11410	COG0815	Transfers the fatty acyl group on membrane lipoproteins
pbN1_11420	COG4535	Mg2 and Co2 transporter CorC
pbN1_11430	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
pbN1_11440	COG1702	phosphate starvation-inducible protein PhoH
pbN1_11450	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
pbN1_11470	COG0583	DNA-binding transcription factor activity
pbN1_11500	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
pbN1_11530	COG0583	DNA-binding transcription factor activity
pbN1_11540	COG0477	Major facilitator Superfamily
pbN1_11560	COG2177	Part of the ABC transporter FtsEX involved in
pbN1_11570	COG2884	Cell division ATP-binding protein ftsE
pbN1_11590	COG0612	Peptidase, M16
pbN1_11610	COG0742	ribosomal rna small subunit methyltransferase
pbN1_11620	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
pbN1_11630	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
pbN1_11640	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
pbN1_11650	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
pbN1_11670	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
pbN1_11680	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
pbN1_11690	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
pbN1_11700	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
pbN1_11710	COG0193	aminoacyl-tRNA hydrolase activity
pbN1_11720	COG0012	GTP binding
pbN1_11760	COG0463	Glycosyl transferase, family 2
pbN1_11780	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
pbN1_11790	COG1028	Short-chain dehydrogenase reductase Sdr
pbN1_11810	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
pbN1_11820	COG3568	Endonuclease Exonuclease Phosphatase
pbN1_11830	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
pbN1_11850	COG0174	glutamine synthetase
pbN1_11870	COG3852	Histidine kinase
pbN1_11900	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
pbN1_11910	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
pbN1_11930	COG0237	dephospho-CoA kinase activity
pbN1_11940	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
pbN1_11950	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
pbN1_12010	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
pbN1_12020	COG0305	Participates in initiation and elongation during chromosome replication
pbN1_12030	COG0359	binds to the 23S rRNA
pbN1_12040	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
pbN1_12050	COG2965	DNA replication, synthesis of RNA primer
pbN1_12060	COG0360	Binds together with S18 to 16S ribosomal RNA
pbN1_12070	COG1643	Atp-dependent helicase
pbN1_12110	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
pbN1_12140	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
pbN1_12150	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
pbN1_12160	COG1136	(ABC) transporter
pbN1_12160	COG0577	efflux transmembrane transporter activity
pbN1_12180	COG1136	(ABC) transporter
pbN1_12180	COG0577	efflux transmembrane transporter activity
pbN1_12200	COG1187	pseudouridine synthase activity
pbN1_12210	COG1320	monovalent cation:proton antiporter activity
pbN1_12220	COG2212	antiporter activity
pbN1_12240	COG0651	ATP synthesis coupled electron transport
pbN1_12250	COG1006	Multisubunit Na H antiporter MnhC subunit
pbN1_12260	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
pbN1_12260	COG2111	Na H antiporter
pbN1_12280	COG1556	Lactate utilization protein
pbN1_12300	COG1139	Iron-sulfur cluster binding protein
pbN1_12310	COG0247	lactate metabolic process
pbN1_12320	COG1414	Transcriptional regulator
pbN1_12330	COG1686	Belongs to the peptidase S11 family
pbN1_12360	COG0281	malic enzyme
pbN1_12360	COG0280	phosphate acetyltransferase
pbN1_12370	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
pbN1_12380	COG5001	Diguanylate cyclase
pbN1_12390	COG1309	transcriptional regulator
pbN1_12410	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
pbN1_12420	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
pbN1_12460	COG0783	Belongs to the Dps family
pbN1_12480	COG0443	Heat shock 70 kDa protein
pbN1_12520	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
pbN1_12530	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
pbN1_12610	COG0535	radical SAM domain protein
pbN1_12640	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
pbN1_12650	COG0167	dihydroorotate dehydrogenase activity
pbN1_12670	COG1960	acyl-CoA dehydrogenase activity
pbN1_12690	COG5654	RES domain protein
pbN1_12750	COG4969	Belongs to the N-Me-Phe pilin family
pbN1_12810	COG4453	Protein conserved in bacteria
pbN1_12910	COG2816	NAD+ diphosphatase activity
pbN1_12980	COG2909	trisaccharide binding
pbN1_13030	COG1024	Enoyl-CoA hydratase
pbN1_13030	COG1250	3-hydroxyacyl-CoA dehydrogenase
pbN1_13040	COG1309	transcriptional regulator
pbN1_13050	COG1802	Transcriptional regulator
pbN1_13100	COG1960	acyl-CoA dehydrogenase activity
pbN1_13110	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
pbN1_13110	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
pbN1_13120	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
pbN1_13120	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
pbN1_13160	COG1804	L-carnitine dehydratase bile acid-inducible protein F
pbN1_13220	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
pbN1_13240	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
pbN1_13290	COG0438	transferase activity, transferring glycosyl groups
pbN1_13380	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
pbN1_13390	COG3608	succinylglutamate desuccinylase aspartoacylase
pbN1_13390	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
pbN1_13430	COG1902	pentaerythritol trinitrate reductase activity
pbN1_13430	COG0446	pyridine nucleotide-disulphide oxidoreductase
pbN1_13480	COG4372	Transposase
pbN1_13540	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
pbN1_13550	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
pbN1_13570	COG0437	4 iron, 4 sulfur cluster binding
pbN1_13610	COG2189	Belongs to the N(4) N(6)-methyltransferase family
pbN1_13660	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
pbN1_13720	COG1028	Short-chain dehydrogenase reductase Sdr
pbN1_13810	COG4974	Belongs to the 'phage' integrase family
pbN1_13840	COG1797	cobyrinic acid a,c-diamide synthase activity
pbN1_13870	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
pbN1_13930	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
pbN1_13950	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
pbN1_13980	COG0820	rRNA (adenine-C2-)-methyltransferase activity
pbN1_14060	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
pbN1_14130	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
pbN1_14140	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
pbN1_14170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
pbN1_14300	COG1944	ATP diphosphatase activity
pbN1_14310	COG1024	Enoyl-CoA hydratase
pbN1_14400	COG2853	Lipoprotein
pbN1_14440	COG0564	pseudouridine synthase activity
pbN1_14470	COG3134	Outer membrane lipoprotein
pbN1_14510	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
pbN1_14530	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
pbN1_14550	COG0069	glutamate synthase activity
pbN1_14550	COG0067	glutamate synthase
pbN1_14550	COG0070	glutamate synthase
pbN1_14570	COG0232	Belongs to the dGTPase family. Type 2 subfamily
pbN1_14580	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
pbN1_14590	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
pbN1_14660	COG1965	Belongs to the frataxin family
pbN1_14730	COG1088	dTDP-glucose 4,6-dehydratase activity
pbN1_14760	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
pbN1_14800	COG0284	orotidine-5'-phosphate decarboxylase activity
pbN1_14820	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
pbN1_14830	COG3161	chorismate lyase activity
pbN1_14840	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
pbN1_14880	COG0655	NAD(P)H dehydrogenase (quinone) activity
pbN1_14890	COG1741	Belongs to the pirin family
pbN1_14970	COG3668	Plasmid stabilization system
pbN1_14990	COG0183	Belongs to the thiolase family
pbN1_15000	COG1024	Enoyl-CoA hydratase
pbN1_15000	COG1250	3-hydroxyacyl-CoA dehydrogenase
pbN1_15010	COG2067	long-chain fatty acid transport protein
pbN1_15020	COG1607	acyl-coa hydrolase
pbN1_15030	COG1024	Enoyl-CoA hydratase
pbN1_15030	COG1250	3-hydroxyacyl-CoA dehydrogenase
pbN1_15050	COG1960	acyl-CoA dehydrogenase activity
pbN1_15160	COG5265	(ABC) transporter
pbN1_15190	COG0675	Transposase, IS605 OrfB family
pbN1_15210	COG3077	Addiction module antitoxin, RelB DinJ family
pbN1_15250	COG0583	DNA-binding transcription factor activity
pbN1_15260	COG0730	response to heat
pbN1_15290	COG0175	sulfate reduction
pbN1_15310	COG0175	sulfate reduction
pbN1_15320	COG2895	sulfate adenylyltransferase (ATP) activity
pbN1_15350	COG0330	HflC and HflK could
pbN1_15380	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
pbN1_15390	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
pbN1_15410	COG0824	Thioesterase
pbN1_15450	COG0823	Involved in the tonB-independent uptake of proteins
pbN1_15460	COG2885	chlorophyll binding
pbN1_15470	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
pbN1_15480	COG0602	queuosine metabolic process
pbN1_15490	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
pbN1_15580	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
pbN1_15590	COG0582	viral genome integration into host DNA
pbN1_15630	COG0318	PFAM AMP-dependent synthetase and ligase
pbN1_15730	COG0812	UDP-N-acetylmuramate dehydrogenase activity
pbN1_15740	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
pbN1_15750	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
pbN1_15760	COG1546	Belongs to the CinA family
pbN1_15770	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
pbN1_15780	COG2137	regulation of response to DNA damage stimulus
pbN1_15790	COG1137	ATPase activity
pbN1_15800	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
pbN1_15810	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
pbN1_15830	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
pbN1_15840	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
pbN1_15850	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
pbN1_15860	COG0741	lytic transglycosylase activity
pbN1_15890	COG0617	tRNA 3'-terminal CCA addition
pbN1_15960	COG0037	tRNA processing
pbN1_15980	COG1238	metal cluster binding
pbN1_16030	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
pbN1_16040	COG1484	DNA-dependent DNA replication
pbN1_16060	COG1028	Short-chain dehydrogenase reductase Sdr
pbN1_16140	COG1484	DNA-dependent DNA replication
pbN1_16170	COG2003	Belongs to the UPF0758 family
pbN1_16350	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
pbN1_16360	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
pbN1_16490	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
pbN1_16530	COG1196	nuclear chromosome segregation
pbN1_16680	COG3039	Transposase
pbN1_16720	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
pbN1_16760	COG2226	methyltransferase
pbN1_16930	COG4191	Histidine kinase
pbN1_16950	COG2204	response regulator
pbN1_16960	COG4191	Histidine kinase
pbN1_16980	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
pbN1_16990	COG1194	a g-specific adenine glycosylase
pbN1_17010	COG2860	membrane
pbN1_17030	COG1970	mechanosensitive ion channel activity
pbN1_17040	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
pbN1_17050	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
pbN1_17090	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
pbN1_17100	COG1074	ATP-dependent DNA helicase activity
pbN1_17110	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
pbN1_17120	COG0446	pyridine nucleotide-disulphide oxidoreductase
pbN1_17130	COG0446	pyridine nucleotide-disulphide oxidoreductase
pbN1_17150	COG0071	Belongs to the small heat shock protein (HSP20) family
pbN1_17230	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
pbN1_17300	COG3383	formate dehydrogenase (NAD+) activity
pbN1_17320	COG1773	rubredoxin
pbN1_17390	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
pbN1_17430	COG0183	Belongs to the thiolase family
pbN1_17470	COG0826	peptidase U32
pbN1_17490	COG0488	(ABC) transporter
pbN1_17500	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
pbN1_17510	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
pbN1_17510	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
pbN1_17520	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
pbN1_17530	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
pbN1_17580	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
pbN1_17590	COG2813	Specifically methylates the guanine in position
pbN1_17590	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
pbN1_17630	COG2814	Major facilitator Superfamily
pbN1_17650	COG0288	reversible hydration of carbon dioxide
pbN1_17660	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
pbN1_17680	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
pbN1_17700	COG0569	domain protein
pbN1_17710	COG2204	response regulator
pbN1_17720	COG5000	phosphorelay sensor kinase activity
pbN1_17770	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
pbN1_17780	COG0706	membrane insertase activity
pbN1_17790	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
pbN1_17800	COG0594	ribonuclease P activity
pbN1_17810	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
pbN1_17820	COG0592	DNA-directed DNA polymerase activity
pbN1_17870	COG4804	nuclease activity
pbN1_17890	COG0405	Gamma-glutamyltransferase
pbN1_17910	COG0393	Putative heavy-metal-binding
pbN1_17920	COG0488	(ABC) transporter
pbN1_17930	COG3108	Peptidase M15
pbN1_17940	COG2989	Protein conserved in bacteria
pbN1_18020	COG1475	DNA binding
pbN1_18030	COG1192	Involved in chromosome partitioning
pbN1_18040	COG0357	Ribosomal RNA small subunit methyltransferase G
pbN1_18050	COG0445	tRNA wobble uridine modification
pbN1_18100	COG0437	4 iron, 4 sulfur cluster binding
pbN1_18110	COG3383	formate dehydrogenase (NAD+) activity
pbN1_18110	COG0243	molybdopterin cofactor binding
pbN1_18180	COG0746	molybdenum cofactor guanylyltransferase activity
pbN1_18190	COG0840	transmembrane signaling receptor activity
pbN1_18200	COG1763	Mo-molybdopterin cofactor biosynthetic process
pbN1_18230	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
pbN1_18240	COG0242	peptide deformylase activity
pbN1_18250	COG1652	LysM domain
pbN1_18260	COG0758	DNA mediated transformation
pbN1_18270	COG2922	Belongs to the Smg family
pbN1_18320	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
pbN1_18330	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
pbN1_18350	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
pbN1_18370	COG1187	pseudouridine synthase activity
pbN1_18390	COG2974	May be involved in recombination
pbN1_18410	COG0784	Response regulator, receiver
pbN1_18420	COG4251	negative regulation of phosphorylation
pbN1_18440	COG1804	L-carnitine dehydratase bile acid-inducible protein F
pbN1_18460	COG0583	DNA-binding transcription factor activity
pbN1_18500	COG0356	it plays a direct role in the translocation of protons across the membrane
pbN1_18520	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
pbN1_18530	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
pbN1_18540	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
pbN1_18550	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
pbN1_18560	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
pbN1_18570	COG0355	proton-transporting ATP synthase activity, rotational mechanism
pbN1_18600	COG2226	methyltransferase
pbN1_18620	COG0745	RESPONSE REGULATOR receiver
pbN1_18650	COG0121	glutamine amidotransferase
pbN1_18660	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
pbN1_18670	COG0154	amidase activity
pbN1_18680	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
pbN1_18690	COG1077	Cell shape determining protein MreB Mrl
pbN1_18720	COG0768	penicillin binding
pbN1_18730	COG0772	Belongs to the SEDS family
pbN1_18750	COG1686	Belongs to the peptidase S11 family
pbN1_18770	COG2921	Belongs to the UPF0250 family
pbN1_18780	COG0321	lipoyl(octanoyl) transferase activity
pbN1_18790	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
pbN1_18830	COG3245	cytochrome
pbN1_18840	COG1652	LysM domain
pbN1_18850	COG0500	methyltransferase
pbN1_18890	COG2733	membrane
pbN1_18930	COG0420	3'-5' exonuclease activity
pbN1_18950	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
pbN1_19030	COG5012	cobalamin binding
pbN1_19110	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
pbN1_19150	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
pbN1_19180	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
pbN1_19200	COG0517	IMP dehydrogenase activity
pbN1_19210	COG0574	Belongs to the PEP-utilizing enzyme family
pbN1_19210	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
pbN1_19260	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
pbN1_19260	COG0674	pyruvate-flavodoxin oxidoreductase activity
pbN1_19270	COG1013	pyruvate-flavodoxin oxidoreductase activity
pbN1_19280	COG0004	ammonium transporteR
pbN1_19290	COG0347	Belongs to the P(II) protein family
pbN1_19320	COG0606	chelatase, subunit chli
pbN1_19330	COG2814	Major facilitator Superfamily
pbN1_19440	COG0330	HflC and HflK could
pbN1_19470	COG2116	formate transmembrane transporter activity
pbN1_19480	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
pbN1_19540	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
pbN1_19550	COG3876	Protein conserved in bacteria
pbN1_19570	COG4772	TonB-dependent receptor
pbN1_19600	COG0861	Integral membrane protein TerC family
pbN1_19620	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
pbN1_19640	COG4584	PFAM Integrase catalytic
pbN1_19670	COG3284	Transcriptional regulator
pbN1_19700	COG1484	DNA-dependent DNA replication
pbN1_19750	COG1518	maintenance of DNA repeat elements
pbN1_19920	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
pbN1_20010	COG1368	sulfuric ester hydrolase activity
pbN1_20040	COG0642	Histidine kinase
pbN1_20050	COG0708	Exodeoxyribonuclease III
pbN1_20060	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
pbN1_20080	COG0243	molybdopterin cofactor binding
pbN1_20130	COG1484	DNA-dependent DNA replication
pbN1_20140	COG0725	ABC transporter, periplasmic molybdate-binding protein
pbN1_20150	COG4149	molybdate abc transporter
pbN1_20160	COG3842	ATPase activity
pbN1_20170	COG4772	TonB-dependent receptor
pbN1_20190	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
pbN1_20200	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
pbN1_20210	COG1120	ATPase activity
pbN1_20220	COG0500	methyltransferase
pbN1_20230	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
pbN1_20250	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
pbN1_20260	COG1120	ATPase activity
pbN1_20360	COG0583	DNA-binding transcription factor activity
pbN1_20460	COG1484	DNA-dependent DNA replication
pbN1_20500	COG2146	nitrite reductase [NAD(P)H] activity
pbN1_20510	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
pbN1_20530	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
pbN1_20550	COG0346	lactoylglutathione lyase activity
pbN1_20570	COG4569	acetaldehyde dehydrogenase (acetylating) activity
pbN1_20580	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
pbN1_20610	COG2267	carboxylic ester hydrolase activity
pbN1_20620	COG0583	DNA-binding transcription factor activity
pbN1_20630	COG1396	sequence-specific DNA binding
pbN1_20650	COG0582	viral genome integration into host DNA
pbN1_20670	COG2022	thiamine diphosphate biosynthetic process
pbN1_20680	COG0220	tRNA (guanine-N7-)-methyltransferase activity
pbN1_20690	COG0616	signal peptide processing
pbN1_20710	COG0635	Involved in the biosynthesis of porphyrin-containing compound
pbN1_20720	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
pbN1_20730	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
pbN1_20740	COG0631	protein serine/threonine phosphatase activity
pbN1_20750	COG0515	serine threonine protein kinase
pbN1_20760	COG1561	YicC-like family, N-terminal region
pbN1_20770	COG0582	viral genome integration into host DNA
pbN1_20870	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
pbN1_20940	COG0189	ligase activity
pbN1_20960	COG0697	spore germination
pbN1_20970	COG0583	DNA-binding transcription factor activity
pbN1_21010	COG0488	(ABC) transporter
pbN1_21020	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
pbN1_21060	COG1278	Cold shock
pbN1_21090	COG1305	Transglutaminase-like
pbN1_21100	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
pbN1_21110	COG3045	CreA protein
pbN1_21140	COG0484	heat shock protein binding
pbN1_21150	COG0194	GDP metabolic process
pbN1_21160	COG1758	RNA polymerase activity
pbN1_21170	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
pbN1_21220	COG3850	Histidine kinase
pbN1_21230	COG2197	response regulator
pbN1_21250	COG4133	protoheme IX ABC transporter activity
pbN1_21290	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
pbN1_21300	COG1138	Cytochrome C-type biogenesis protein
pbN1_21310	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
pbN1_21320	COG3088	subunit of a heme lyase
pbN1_21330	COG3088	subunit of a heme lyase
pbN1_21330	COG4235	cytochrome complex assembly
pbN1_21360	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
pbN1_21390	COG1742	UPF0060 membrane protein
pbN1_21400	COG0789	Transcriptional regulator
pbN1_21490	COG1368	sulfuric ester hydrolase activity
pbN1_21500	COG3162	membrane
pbN1_21550	COG1024	Enoyl-CoA hydratase
pbN1_21560	COG1250	3-hydroxyacyl-CoA dehydrogenase
pbN1_21570	COG2050	protein possibly involved in aromatic compounds catabolism
pbN1_21590	COG3396	Phenylacetate-CoA oxygenase
pbN1_21600	COG3460	Phenylacetate-CoA oxygenase
pbN1_21610	COG3396	Phenylacetate-CoA oxygenase
pbN1_21620	COG2151	metal-sulfur cluster biosynthetic enzyme
pbN1_21630	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
pbN1_21690	COG1902	pentaerythritol trinitrate reductase activity
pbN1_21720	COG0513	Belongs to the DEAD box helicase family
pbN1_21730	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
pbN1_21740	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
pbN1_21770	COG4232	protein-disulfide reductase activity
pbN1_21800	COG0861	Integral membrane protein TerC family
pbN1_21850	COG1131	(ABC) transporter
pbN1_21860	COG0625	glutathione transferase activity
pbN1_21900	COG3154	lipid carrier protein
pbN1_21910	COG0826	peptidase U32
pbN1_21920	COG0826	peptidase U32
pbN1_21990	COG0252	asparaginase activity
pbN1_22000	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
pbN1_22010	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
pbN1_22020	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
pbN1_22030	COG0018	arginyl-trna synthetase
pbN1_22050	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
pbN1_22070	COG2902	Dehydrogenase
pbN1_22080	COG3158	transport of potassium into the cell
pbN1_22090	COG0686	Belongs to the AlaDH PNT family
pbN1_22100	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
pbN1_22120	COG3243	poly(R)-hydroxyalkanoic acid synthase
pbN1_22140	COG0789	Transcriptional regulator
pbN1_22160	COG0288	reversible hydration of carbon dioxide
pbN1_22170	COG0183	Belongs to the thiolase family
pbN1_22180	COG1960	acyl-CoA dehydrogenase activity
pbN1_22190	COG1024	Enoyl-CoA hydratase
pbN1_22220	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
pbN1_22230	COG1660	Displays ATPase and GTPase activities
pbN1_22350	COG0604	alcohol dehydrogenase
pbN1_22370	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
pbN1_22410	COG2204	response regulator
pbN1_22430	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
pbN1_22460	COG0697	spore germination
pbN1_22470	COG0217	transcriptional regulatory protein
pbN1_22490	COG1555	photosystem II stabilization
pbN1_22490	COG1596	polysaccharide export
pbN1_22510	COG0513	Belongs to the DEAD box helicase family
pbN1_22530	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
pbN1_22540	COG1492	cobalamin metabolic process
pbN1_22560	COG0745	RESPONSE REGULATOR receiver
pbN1_22570	COG2205	protein histidine kinase activity
pbN1_22580	COG1024	Enoyl-CoA hydratase
pbN1_22590	COG3162	membrane
pbN1_22600	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
pbN1_22700	COG4964	Belongs to the GSP D family
pbN1_22760	COG2201	protein-glutamate methylesterase activity
pbN1_22840	COG0114	fumarate hydratase activity
pbN1_22850	COG1802	Transcriptional regulator
pbN1_22860	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
pbN1_22860	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
pbN1_22870	COG1703	isobutyryl-CoA mutase activity
pbN1_22880	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
pbN1_22900	COG4770	biotin carboxylase activity
pbN1_22930	COG2207	Transcriptional regulator
pbN1_22940	COG2807	transmembrane transport
pbN1_23010	COG1703	isobutyryl-CoA mutase activity
pbN1_23010	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
pbN1_23010	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
pbN1_23040	COG0586	Pfam SNARE associated Golgi protein
pbN1_23060	COG1022	Amp-dependent synthetase and ligase
pbN1_23080	COG0559	Belongs to the binding-protein-dependent transport system permease family
pbN1_23130	COG1804	L-carnitine dehydratase bile acid-inducible protein F
pbN1_23160	COG2205	protein histidine kinase activity
pbN1_23160	COG0784	Response regulator, receiver
pbN1_23160	COG2198	Histidine kinase
pbN1_23210	COG0277	FAD linked oxidase domain protein
pbN1_23220	COG1522	sequence-specific DNA binding
pbN1_23230	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
pbN1_23240	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
pbN1_23260	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
pbN1_23270	COG0081	regulation of translation
pbN1_23280	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
pbN1_23290	COG0222	ribosome binding
pbN1_23300	COG0085	RNA polymerase activity
pbN1_23310	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
pbN1_23320	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
pbN1_23330	COG0049	tRNA binding
pbN1_23340	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
pbN1_23350	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
pbN1_23360	COG0051	transcription antitermination factor activity, RNA binding
pbN1_23370	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
pbN1_23380	COG0088	Forms part of the polypeptide exit tunnel
pbN1_23390	COG0089	rRNA binding
pbN1_23400	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
pbN1_23410	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
pbN1_23420	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
pbN1_23430	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
pbN1_23440	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
pbN1_23450	COG0255	Belongs to the universal ribosomal protein uL29 family
pbN1_23460	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
pbN1_23470	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
pbN1_23480	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
pbN1_23490	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
pbN1_23500	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
pbN1_23510	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
pbN1_23520	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
pbN1_23530	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
pbN1_23540	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
pbN1_23550	COG1841	ribosomal large subunit assembly
pbN1_23560	COG0200	Binds to the 23S rRNA
pbN1_23570	COG0201	protein transport
pbN1_23580	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
pbN1_23590	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
pbN1_23600	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
pbN1_23610	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
pbN1_23620	COG0202	RNA polymerase activity
pbN1_23630	COG0203	ribosomal protein L17
pbN1_23640	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
pbN1_23660	COG2814	Major facilitator Superfamily
pbN1_23680	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
pbN1_23710	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
pbN1_23760	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
pbN1_23790	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
pbN1_23820	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
pbN1_23830	COG2084	Dehydrogenase
pbN1_23840	COG2084	Dehydrogenase
pbN1_23860	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
pbN1_23870	COG0436	Aminotransferase
pbN1_23920	COG3744	PilT protein domain protein
pbN1_24000	COG4969	Belongs to the N-Me-Phe pilin family
pbN1_24070	COG0247	lactate metabolic process
pbN1_24110	COG1032	radical SAM domain protein
pbN1_24150	COG3781	membrane
pbN1_24160	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
pbN1_24180	COG1560	Kdo2-lipid A biosynthetic process
pbN1_24190	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
pbN1_24220	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
pbN1_24240	COG2255	four-way junction helicase activity
pbN1_24250	COG0632	four-way junction helicase activity
pbN1_24290	COG0424	maF-like protein
pbN1_24300	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
pbN1_24310	COG0799	negative regulation of ribosome biogenesis
pbN1_24320	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
pbN1_24350	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
pbN1_24390	COG2192	nodulation
pbN1_24400	COG0438	transferase activity, transferring glycosyl groups
pbN1_24460	COG1132	(ABC) transporter
pbN1_24490	COG0438	transferase activity, transferring glycosyl groups
pbN1_24520	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
pbN1_24560	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
pbN1_24590	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
pbN1_24650	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
pbN1_24660	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
pbN1_24680	COG1404	Belongs to the peptidase S8 family
pbN1_24690	COG0675	Transposase, IS605 OrfB family
pbN1_24700	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
pbN1_24700	COG1648	precorrin-2 dehydrogenase activity
pbN1_24710	COG0778	Nitroreductase
pbN1_24770	COG0583	DNA-binding transcription factor activity
pbN1_24790	COG0668	transmembrane transport
pbN1_24810	COG0741	lytic transglycosylase activity
pbN1_24840	COG1028	Short-chain dehydrogenase reductase Sdr
pbN1_24850	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
pbN1_24860	COG1960	acyl-CoA dehydrogenase activity
pbN1_24920	COG1024	Enoyl-CoA hydratase
pbN1_24930	COG1250	3-hydroxyacyl-CoA dehydrogenase
pbN1_24940	COG0183	Belongs to the thiolase family
pbN1_24950	COG0433	COG0433 Predicted ATPase
pbN1_24990	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
pbN1_25000	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
pbN1_25010	COG1278	Cold shock
pbN1_25020	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
pbN1_25040	COG0672	)-iron permease
pbN1_25080	COG1002	Type II restriction enzyme, methylase subunits
pbN1_25110	COG1061	Type III restriction enzyme res subunit
pbN1_25130	COG1061	Type III restriction enzyme res subunit
pbN1_25140	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
pbN1_25150	COG1538	Outer membrane efflux protein
pbN1_25160	COG1136	(ABC) transporter
pbN1_25160	COG0577	efflux transmembrane transporter activity
pbN1_25170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
pbN1_25260	COG5001	Diguanylate cyclase
pbN1_25290	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
pbN1_25300	COG3132	Protein of unknown function, DUF480
pbN1_25310	COG0129	dihydroxy-acid dehydratase activity
pbN1_25320	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
pbN1_25340	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
pbN1_25350	COG0730	response to heat
pbN1_25360	COG1262	PFAM Formylglycine-generating sulfatase enzyme
pbN1_25370	COG0803	Belongs to the bacterial solute-binding protein 9 family
pbN1_25390	COG1121	(ABC) transporter
pbN1_25400	COG0735	belongs to the Fur family
pbN1_25410	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
pbN1_25410	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
pbN1_25450	COG2205	protein histidine kinase activity
pbN1_25460	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
pbN1_25490	COG1981	membrane
pbN1_25550	COG0762	integral membrane protein
pbN1_25560	COG1872	DUF167
pbN1_25570	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
pbN1_25580	COG0540	Belongs to the ATCase OTCase family
pbN1_25590	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
pbN1_25600	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
pbN1_25610	COG1678	Uncharacterized ACR, COG1678
pbN1_25620	COG0643	Histidine kinase
pbN1_25620	COG2198	Histidine kinase
pbN1_25630	COG0840	transmembrane signaling receptor activity
pbN1_25640	COG0835	chemotaxis
pbN1_25690	COG0352	thiamine-phosphate diphosphorylase activity
pbN1_25700	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
pbN1_25710	COG2239	Acts as a magnesium transporter
pbN1_25720	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
pbN1_25730	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
pbN1_25750	COG0557	exoribonuclease II activity
pbN1_25760	COG2226	methyltransferase
pbN1_25770	COG3150	esterase
pbN1_25780	COG1968	undecaprenyl-diphosphatase activity
pbN1_25830	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
pbN1_25840	COG0351	phosphomethylpyrimidine kinase
pbN1_25850	COG2119	membrane
pbN1_25870	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
pbN1_25880	COG3258	Cytochrome c
pbN1_25930	COG0515	serine threonine protein kinase
pbN1_25930	COG1262	PFAM Formylglycine-generating sulfatase enzyme
pbN1_25950	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
pbN1_25960	COG1538	Outer membrane efflux protein
pbN1_25980	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
pbN1_25990	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
pbN1_26000	COG2274	protein secretion by the type I secretion system
pbN1_26140	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
pbN1_26150	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
pbN1_26200	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
pbN1_26220	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
pbN1_26260	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
pbN1_26270	COG1459	type II secretion system
pbN1_26280	COG2165	general secretion pathway protein
pbN1_26300	COG2165	general secretion pathway protein
pbN1_26360	COG1450	Type ii and iii secretion system protein
pbN1_26410	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
pbN1_26450	COG0438	transferase activity, transferring glycosyl groups
pbN1_26460	COG3754	Rhamnan synthesis protein F
pbN1_26590	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
pbN1_26600	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
pbN1_26640	COG1404	Belongs to the peptidase S8 family
pbN1_26680	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
pbN1_26710	COG0537	adenosine 5'-monophosphoramidase activity
pbN1_26720	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
pbN1_26770	COG2264	protein methyltransferase activity
pbN1_26780	COG0439	Biotin carboxylase
pbN1_26800	COG0511	ligase activity, forming carbon-carbon bonds
pbN1_26810	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
pbN1_26820	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
pbN1_26840	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
pbN1_26850	COG2823	Periplasmic or secreted lipoprotein
pbN1_26860	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
pbN1_26890	COG0418	dihydroorotase activity
pbN1_26910	COG2001	Belongs to the MraZ family
pbN1_26920	COG0275	rRNA processing
pbN1_26950	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
pbN1_26960	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
pbN1_26970	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
pbN1_26980	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
pbN1_26990	COG0772	Belongs to the SEDS family
pbN1_27000	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
pbN1_27010	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
pbN1_27020	COG1181	Belongs to the D-alanine--D-alanine ligase family
pbN1_27030	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
pbN1_27050	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
pbN1_27060	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
pbN1_27090	COG0653	protein targeting
pbN1_27110	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
pbN1_27130	COG2967	ApaG domain
pbN1_27160	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
pbN1_27180	COG1862	Preprotein translocase
pbN1_27190	COG0343	queuine tRNA-ribosyltransferase activity
pbN1_27200	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
pbN1_27210	COG0583	DNA-binding transcription factor activity
pbN1_27230	COG0670	Belongs to the BI1 family
pbN1_27240	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
pbN1_27250	COG1253	flavin adenine dinucleotide binding
pbN1_27280	COG0825	malonyl-CoA metabolic process
pbN1_27290	COG0037	tRNA processing
pbN1_27300	COG4566	intracellular signal transduction
pbN1_27350	COG2423	ornithine cyclodeaminase activity
pbN1_27370	COG5212	phosphodiesterase
pbN1_27380	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
pbN1_27390	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
pbN1_27400	COG0546	phosphoglycolate phosphatase activity
pbN1_27450	COG0626	cystathionine gamma-synthase activity
pbN1_27480	COG2824	Alkylphosphonate utilization operon protein PhnA
pbN1_27500	COG3260	NADH ubiquinone oxidoreductase 20
pbN1_27510	COG0649	NAD binding
pbN1_27520	COG0651	ATP synthesis coupled electron transport
pbN1_27540	COG0650	Formate hydrogenlyase subunit 4
pbN1_27550	COG0651	ATP synthesis coupled electron transport
pbN1_27590	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
pbN1_27600	COG0134	indole-3-glycerol-phosphate synthase activity
pbN1_27620	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
pbN1_27640	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
pbN1_27690	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
pbN1_27720	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
pbN1_27740	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
pbN1_27800	COG1612	heme a metabolic process
pbN1_27810	COG0109	protoheme IX farnesyltransferase activity
pbN1_27820	COG1999	signal sequence binding
pbN1_27830	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
pbN1_27900	COG0489	protein tyrosine kinase activity
pbN1_27920	COG3267	Type II secretory pathway component ExeA
pbN1_27920	COG3409	Peptidoglycan-binding domain 1 protein
pbN1_27960	COG0438	transferase activity, transferring glycosyl groups
pbN1_27970	COG0367	asparagine synthase
pbN1_28000	COG0438	transferase activity, transferring glycosyl groups
pbN1_28060	COG0297	glycogen (starch) synthase activity
pbN1_28110	COG3119	arylsulfatase activity
pbN1_28120	COG1215	transferase activity, transferring glycosyl groups
pbN1_28200	COG2244	polysaccharide biosynthetic process
pbN1_28230	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
pbN1_28240	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
pbN1_28250	COG1960	acyl-CoA dehydrogenase activity
pbN1_28260	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
pbN1_28270	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
pbN1_28290	COG0471	metal ion transport
pbN1_28290	COG3273	potassium ion transport
pbN1_28300	COG1218	3'(2'),5'-bisphosphate nucleotidase
pbN1_28310	COG0175	sulfate reduction
pbN1_28340	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
pbN1_28350	COG0071	Belongs to the small heat shock protein (HSP20) family
pbN1_28370	COG0494	nUDIX hydrolase
pbN1_28400	COG2204	response regulator
pbN1_28410	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
pbN1_28470	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
pbN1_28480	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
pbN1_28530	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
pbN1_28560	COG1610	YqeY-like protein
pbN1_28570	COG0828	Belongs to the bacterial ribosomal protein bS21 family
pbN1_28600	COG0277	FAD linked oxidase domain protein
pbN1_28620	COG0277	FAD linked oxidase domain protein
pbN1_28630	COG0247	lactate metabolic process
pbN1_28660	COG0598	Magnesium transport protein CorA
pbN1_28680	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
pbN1_28710	COG0513	Belongs to the DEAD box helicase family
pbN1_28720	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
pbN1_28740	COG1653	transport
pbN1_28750	COG0584	glycerophosphoryl diester phosphodiesterase
pbN1_28760	COG0142	geranyltranstransferase activity
pbN1_28770	COG2030	dehydratase
pbN1_28780	COG1469	GTP cyclohydrolase I activity
pbN1_28790	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
pbN1_28800	COG0142	geranyltranstransferase activity
pbN1_28810	COG1722	exodeoxyribonuclease VII activity
pbN1_28830	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
pbN1_28840	COG1047	Peptidyl-prolyl cis-trans
pbN1_28850	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
pbN1_28860	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
pbN1_28870	COG0196	riboflavin kinase activity
pbN1_28880	COG0860	N-Acetylmuramoyl-L-alanine amidase
pbN1_28910	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
pbN1_28920	COG1028	Short-chain dehydrogenase reductase Sdr
pbN1_28950	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
pbN1_28960	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
pbN1_29010	COG2224	Isocitrate lyase
pbN1_29020	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
pbN1_29030	COG0542	response to heat
pbN1_29040	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
pbN1_29050	COG1278	Cold shock
pbN1_29060	COG0267	Belongs to the bacterial ribosomal protein bL33 family
pbN1_29070	COG0227	Belongs to the bacterial ribosomal protein bL28 family
pbN1_29080	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
pbN1_29090	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
pbN1_29120	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
pbN1_29140	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
pbN1_29150	COG1466	dna polymerase III delta subunit
pbN1_29170	COG0495	leucyl-tRNA aminoacylation
pbN1_29200	COG0210	DNA helicase
pbN1_29210	COG1192	Involved in chromosome partitioning
pbN1_29230	COG0280	phosphate acetyltransferase
pbN1_29230	COG0281	malic enzyme
pbN1_29280	COG0450	alkyl hydroperoxide reductase
pbN1_29290	COG1254	Belongs to the acylphosphatase family
pbN1_29300	COG0659	secondary active sulfate transmembrane transporter activity
pbN1_29310	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
pbN1_29310	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
pbN1_29330	COG0489	protein tyrosine kinase activity
pbN1_29340	COG0717	Belongs to the dCTP deaminase family
pbN1_29370	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
pbN1_29410	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
pbN1_29430	COG0402	S-adenosylhomocysteine deaminase activity
pbN1_29450	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
pbN1_29470	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
pbN1_29480	COG0287	Prephenate dehydrogenase
pbN1_29490	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
pbN1_29510	COG0776	regulation of translation
pbN1_29530	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
pbN1_29600	COG2261	transglycosylase associated protein
pbN1_29620	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
pbN1_29620	COG1648	precorrin-2 dehydrogenase activity
pbN1_29640	COG3391	amine dehydrogenase activity
pbN1_29680	COG2010	Cytochrome c
pbN1_29720	COG0535	radical SAM domain protein
pbN1_29740	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
pbN1_29750	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
pbN1_29760	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
pbN1_29770	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
pbN1_29780	COG0291	Belongs to the bacterial ribosomal protein bL35 family
pbN1_29790	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
pbN1_29800	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
pbN1_29810	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
pbN1_29810	COG0072	phenylalanine-tRNA ligase activity
pbN1_29820	COG0776	regulation of translation
pbN1_29840	COG0318	PFAM AMP-dependent synthetase and ligase
pbN1_29880	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
pbN1_29890	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
pbN1_29900	COG0211	Belongs to the bacterial ribosomal protein bL27 family
pbN1_29910	COG0261	This protein binds to 23S rRNA in the presence of protein L20
pbN1_29930	COG0582	viral genome integration into host DNA
pbN1_29940	COG4974	Belongs to the 'phage' integrase family
pbN1_29950	COG2003	Belongs to the UPF0758 family
pbN1_29970	COG0756	dUTP diphosphatase activity
pbN1_29990	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
pbN1_30030	COG0538	isocitrate dehydrogenase activity
pbN1_30050	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
pbN1_30100	COG1346	cytolysis
pbN1_30110	COG1380	Effector of murein hydrolase LrgA
pbN1_30150	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
pbN1_30180	COG0583	DNA-binding transcription factor activity
pbN1_30280	COG0582	viral genome integration into host DNA
pbN1_30450	COG0784	Response regulator, receiver
pbN1_30450	COG2198	Histidine kinase
pbN1_30450	COG2205	protein histidine kinase activity
pbN1_30460	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
pbN1_30480	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
pbN1_30490	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
pbN1_30510	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
pbN1_30520	COG2951	lytic endotransglycosylase activity
pbN1_30530	COG0123	including yeast histone deacetylase and acetoin utilization protein
pbN1_30540	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
pbN1_30550	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
pbN1_30570	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
pbN1_30640	COG1960	acyl-CoA dehydrogenase activity
pbN1_30660	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
pbN1_30690	COG1028	Short-chain dehydrogenase reductase Sdr
pbN1_30700	COG1024	Enoyl-CoA hydratase
pbN1_30710	COG1024	Enoyl-CoA hydratase
pbN1_30730	COG1309	transcriptional regulator
pbN1_30760	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
pbN1_30770	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
pbN1_30810	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
pbN1_30880	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
pbN1_30890	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
pbN1_30910	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
pbN1_30910	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
pbN1_30920	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
pbN1_30930	COG1511	domain protein
pbN1_30930	COG3264	Mechanosensitive ion channel
pbN1_30950	COG0720	synthase
pbN1_30990	COG0527	aspartate kinase activity
pbN1_31060	COG2217	Heavy metal translocating P-type atpase
pbN1_31070	COG0671	phosphoesterase, PA-phosphatase related
pbN1_31120	COG0463	Glycosyl transferase, family 2
pbN1_31130	COG1368	sulfuric ester hydrolase activity
pbN1_31180	COG1448	Aminotransferase
pbN1_31200	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
pbN1_31220	COG1597	lipid kinase activity
pbN1_31230	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
pbN1_31240	COG0837	glucose binding
pbN1_31250	COG0366	Alpha amylase catalytic
pbN1_31270	COG2111	Na H antiporter
pbN1_31270	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
pbN1_31280	COG1006	Multisubunit Na H antiporter MnhC subunit
pbN1_31290	COG0651	ATP synthesis coupled electron transport
pbN1_31300	COG1863	multisubunit Na H antiporter MnhE subunit
pbN1_31310	COG2212	antiporter activity
pbN1_31320	COG1320	monovalent cation:proton antiporter activity
pbN1_31340	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
pbN1_31340	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
pbN1_31340	COG0506	proline dehydrogenase activity
pbN1_31410	COG3384	dioxygenase
pbN1_31420	COG0710	3-dehydroquinate dehydratase activity
pbN1_31430	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
pbN1_31470	COG0589	response to stress
pbN1_31490	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
pbN1_31570	COG2010	Cytochrome c
pbN1_31590	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
pbN1_31620	COG5002	protein histidine kinase activity
pbN1_31630	COG0745	RESPONSE REGULATOR receiver
pbN1_31640	COG2176	DNA-directed DNA polymerase activity
pbN1_31640	COG5002	protein histidine kinase activity
pbN1_31650	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
pbN1_31690	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
pbN1_31690	COG2010	Cytochrome c
pbN1_31700	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
pbN1_31730	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
pbN1_31740	COG2154	pterin-4-alpha-carbinolamine dehydratase
pbN1_31780	COG2135	peptidase activity
pbN1_31820	COG2194	sulfuric ester hydrolase activity
pbN1_31850	COG1215	transferase activity, transferring glycosyl groups
pbN1_31860	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
pbN1_31870	COG0457	Tetratricopeptide repeat
pbN1_31870	COG3118	belongs to the thioredoxin family
pbN1_31900	COG1160	GTP binding
pbN1_31920	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
pbN1_31930	COG0508	dehydrogenase complex catalyzes the overall conversion of
pbN1_31940	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
pbN1_31970	COG4566	intracellular signal transduction
pbN1_31980	COG0840	transmembrane signaling receptor activity
pbN1_32010	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
pbN1_32020	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
pbN1_32030	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
pbN1_32040	COG0009	L-threonylcarbamoyladenylate synthase
pbN1_32110	COG4372	Transposase
pbN1_32140	COG1484	DNA-dependent DNA replication
pbN1_32300	COG5433	transposase activity
pbN1_32330	COG0629	single-stranded DNA binding
pbN1_32420	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
pbN1_32530	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
pbN1_32560	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
pbN1_32590	COG1490	D-aminoacyl-tRNA deacylase activity
pbN1_32600	COG0242	peptide deformylase activity
pbN1_32610	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
pbN1_32630	COG4948	Mandelate Racemase Muconate Lactonizing
pbN1_32640	COG0583	DNA-binding transcription factor activity
pbN1_32690	COG1742	UPF0060 membrane protein
pbN1_32710	COG3177	Filamentation induced by cAMP protein fic
pbN1_32740	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
pbN1_32770	COG0798	PFAM Bile acid sodium symporter
pbN1_32790	COG0183	Belongs to the thiolase family
pbN1_32920	COG1136	(ABC) transporter
pbN1_32930	COG0577	efflux transmembrane transporter activity
pbN1_32930	COG1136	(ABC) transporter
pbN1_32980	COG0121	glutamine amidotransferase
pbN1_33090	COG0657	acetylesterase activity
pbN1_33100	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
pbN1_33120	COG2204	response regulator
pbN1_33180	COG0488	(ABC) transporter
pbN1_33200	COG0604	alcohol dehydrogenase
pbN1_33210	COG0745	RESPONSE REGULATOR receiver
pbN1_33220	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
pbN1_33290	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
pbN1_33300	COG1819	glycosyl
pbN1_33320	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
pbN1_33320	COG2169	Transcriptional regulator
pbN1_33330	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
pbN1_33340	COG0315	cyclic pyranopterin monophosphate synthase activity
pbN1_33350	COG4783	chaperone-mediated protein folding
pbN1_33360	COG0425	Belongs to the sulfur carrier protein TusA family
pbN1_33370	COG0525	valine-tRNA ligase activity
pbN1_33400	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
pbN1_33410	COG0795	lipopolysaccharide-transporting ATPase activity
pbN1_33430	COG0335	large ribosomal subunit rRNA binding
pbN1_33440	COG0336	Belongs to the RNA methyltransferase TrmD family
pbN1_33450	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
pbN1_33460	COG0228	four-way junction DNA binding
pbN1_33480	COG1295	ribonuclease BN
pbN1_33490	COG0655	NAD(P)H dehydrogenase (quinone) activity
pbN1_33510	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
pbN1_33520	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
pbN1_33550	COG1858	cytochrome C peroxidase
pbN1_33600	COG1183	phosphatidylcholine synthase activity
pbN1_33610	COG0688	phosphatidylethanolamine metabolic process
pbN1_33620	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
pbN1_33630	COG0440	acetolactate synthase activity
pbN1_33640	COG0028	Belongs to the TPP enzyme family
pbN1_33690	COG0308	aminopeptidase N
pbN1_33700	COG0517	IMP dehydrogenase activity
pbN1_33700	COG0516	GMP reductase activity
pbN1_33710	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
pbN1_33720	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
pbN1_33730	COG1428	Deoxynucleoside kinase
pbN1_33760	COG0617	tRNA 3'-terminal CCA addition
pbN1_33780	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
pbN1_33790	COG0628	permease
pbN1_33800	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
pbN1_33820	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
pbN1_33840	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
pbN1_33890	COG1028	Short-chain dehydrogenase reductase Sdr
pbN1_33920	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
pbN1_33930	COG2813	Specifically methylates the guanine in position
pbN1_34040	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
pbN1_34080	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
pbN1_34080	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
pbN1_34090	COG0347	Belongs to the P(II) protein family
pbN1_34100	COG2840	Smr protein MutS2
pbN1_34110	COG0492	ferredoxin-NADP+ reductase activity
pbN1_34130	COG1674	ftsk spoiiie
pbN1_34140	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
pbN1_34150	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
pbN1_34170	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
pbN1_34180	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
pbN1_34220	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
pbN1_34240	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
pbN1_34250	COG0366	Alpha amylase catalytic
pbN1_34260	COG0366	Alpha amylase catalytic
pbN1_34270	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
pbN1_34370	COG0517	IMP dehydrogenase activity
pbN1_34390	COG5487	UPF0391 membrane protein
pbN1_34400	COG2823	Periplasmic or secreted lipoprotein
pbN1_34410	COG2823	Periplasmic or secreted lipoprotein
pbN1_34430	COG0628	permease
pbN1_34450	COG5487	UPF0391 membrane protein
pbN1_34510	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
pbN1_34520	COG2193	ferroxidase activity
pbN1_34550	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
pbN1_34600	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
pbN1_34610	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
pbN1_34620	COG1640	4-alpha-glucanotransferase
pbN1_34630	COG0297	glycogen (starch) synthase activity
pbN1_34640	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
pbN1_34660	COG2204	response regulator
pbN1_34710	COG2205	protein histidine kinase activity
pbN1_34740	COG1285	pathogenesis
pbN1_34770	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
pbN1_34800	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
pbN1_34820	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
pbN1_34840	COG2197	response regulator
pbN1_34870	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
pbN1_34870	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
pbN1_34890	COG3300	MHYT domain
pbN1_34890	COG5001	Diguanylate cyclase
pbN1_34900	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
pbN1_34920	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
pbN1_34940	COG0850	regulation of cytokinetic process
pbN1_34960	COG2183	response to ionizing radiation
pbN1_34980	COG1042	CoA-binding domain protein
pbN1_34980	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
pbN1_34980	COG0045	succinate-CoA ligase (ADP-forming) activity
pbN1_35010	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
pbN1_35040	COG4181	ATPase activity
pbN1_35050	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
pbN1_35070	COG1562	ergosterol biosynthetic process
pbN1_35080	COG0577	efflux transmembrane transporter activity
pbN1_35080	COG1136	(ABC) transporter
pbN1_35110	COG4464	protein tyrosine phosphatase activity
pbN1_35130	COG0489	protein tyrosine kinase activity
pbN1_35140	COG0484	heat shock protein binding
pbN1_35190	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
pbN1_35250	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
pbN1_35270	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
pbN1_35330	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
pbN1_35380	COG0438	transferase activity, transferring glycosyl groups
pbN1_35390	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
pbN1_35400	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
pbN1_35410	COG1086	Polysaccharide biosynthesis protein
pbN1_35420	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
pbN1_35440	COG1086	Polysaccharide biosynthesis protein
pbN1_35450	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
pbN1_35490	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
pbN1_35580	COG2916	Histone family protein nucleoid-structuring protein H-NS
pbN1_35590	COG0297	glycogen (starch) synthase activity
pbN1_35620	COG0297	glycogen (starch) synthase activity
pbN1_35750	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
pbN1_35770	COG0297	glycogen (starch) synthase activity
pbN1_35790	COG0297	glycogen (starch) synthase activity
pbN1_35830	COG2916	Histone family protein nucleoid-structuring protein H-NS
pbN1_35870	COG2862	Uncharacterized protein family, UPF0114
pbN1_35880	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
pbN1_35890	COG0024	Methionine aminopeptidase
pbN1_35910	COG0052	Belongs to the universal ribosomal protein uS2 family
pbN1_35920	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
pbN1_35930	COG0528	UMP kinase activity
pbN1_35940	COG0233	cytoplasmic translational termination
pbN1_35950	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
pbN1_35960	COG0575	Belongs to the CDS family
pbN1_35970	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
pbN1_36010	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
pbN1_36020	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
pbN1_36030	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
pbN1_36040	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
pbN1_36050	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
pbN1_36070	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
pbN1_36080	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
pbN1_36090	COG2226	methyltransferase
pbN1_36100	COG2267	carboxylic ester hydrolase activity
pbN1_36110	COG0156	8-amino-7-oxononanoate synthase activity
pbN1_36130	COG3022	response to hydroperoxide
pbN1_36140	COG2866	Carboxypeptidase
pbN1_36250	COG0560	Phosphoserine phosphatase
pbN1_36290	COG0560	Phosphoserine phosphatase
pbN1_36300	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
pbN1_36350	COG3360	Dodecin
pbN1_36370	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
pbN1_36440	COG1028	Short-chain dehydrogenase reductase Sdr
pbN1_36460	COG2133	pyrroloquinoline quinone binding
pbN1_36500	COG2161	toxin-antitoxin pair type II binding
pbN1_36560	COG1607	acyl-coa hydrolase
pbN1_36570	COG4628	conserved protein (DUF2132)
pbN1_36610	COG3284	Transcriptional regulator
pbN1_36620	COG1012	belongs to the aldehyde dehydrogenase family
pbN1_36640	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
pbN1_36660	COG1131	(ABC) transporter
pbN1_36730	COG3284	Transcriptional regulator
pbN1_36740	COG4772	TonB-dependent receptor
pbN1_36810	COG3851	Histidine kinase
pbN1_36920	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
pbN1_36930	COG0488	(ABC) transporter
pbN1_36940	COG5002	protein histidine kinase activity
pbN1_36940	COG5001	Diguanylate cyclase
pbN1_36940	COG3447	MASE1 domain protein
pbN1_36980	COG0583	DNA-binding transcription factor activity
pbN1_37000	COG1215	transferase activity, transferring glycosyl groups
pbN1_37020	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
pbN1_37020	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
pbN1_37030	COG0509	glycine decarboxylation via glycine cleavage system
pbN1_37040	COG0404	The glycine cleavage system catalyzes the degradation of glycine
pbN1_37050	COG0613	PHP domain protein
pbN1_37060	COG0009	L-threonylcarbamoyladenylate synthase
pbN1_37070	COG1994	Peptidase M50
pbN1_37080	COG0180	Tryptophanyl-tRNA synthetase
pbN1_37090	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
pbN1_37100	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
pbN1_37120	COG1196	nuclear chromosome segregation
pbN1_37120	COG0741	lytic transglycosylase activity
pbN1_37120	COG0739	heme binding
pbN1_37150	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
pbN1_37150	COG0047	phosphoribosylformylglycinamidine synthase activity
pbN1_37230	COG0824	Thioesterase
pbN1_37250	COG0504	CTP synthase activity
pbN1_37260	COG2877	3-deoxy-8-phosphooctulonate synthase activity
pbN1_37270	COG0148	phosphopyruvate hydratase activity
pbN1_37280	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
pbN1_37300	COG0791	NLP P60 protein
pbN1_37340	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
pbN1_37360	COG0306	phosphate transporter
pbN1_37380	COG0302	gtp cyclohydrolase
pbN1_37410	COG4681	YaeQ
pbN1_37430	COG1253	flavin adenine dinucleotide binding
pbN1_37440	COG1012	belongs to the aldehyde dehydrogenase family
pbN1_37480	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
pbN1_37570	COG3300	MHYT domain
pbN1_37570	COG5001	Diguanylate cyclase
pbN1_37590	COG0840	transmembrane signaling receptor activity
pbN1_37640	COG0484	heat shock protein binding
pbN1_37730	COG0058	SHG alpha-glucan phosphorylase activity
pbN1_37740	COG0642	Histidine kinase
pbN1_37770	COG4221	oxidoreductase activity
pbN1_37790	COG0318	PFAM AMP-dependent synthetase and ligase
pbN1_37810	COG1309	transcriptional regulator
pbN1_37820	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
pbN1_37840	COG1136	(ABC) transporter
pbN1_37920	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
pbN1_37970	COG4263	nitrous-oxide reductase activity
pbN1_38000	COG2197	response regulator
pbN1_38010	COG3850	Histidine kinase
pbN1_38020	COG2181	nitrate reductase activity
pbN1_38030	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
pbN1_38040	COG1140	nitrate reductase beta subunit
pbN1_38050	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
pbN1_38110	COG2081	HI0933 family
pbN1_38190	COG1671	Belongs to the UPF0178 family
pbN1_38210	COG0534	Mate efflux family protein
pbN1_38340	COG2204	response regulator
pbN1_38350	COG3437	response regulator, receiver
pbN1_38420	COG0484	heat shock protein binding
pbN1_38470	COG3012	SEC-C Motif Domain Protein
pbN1_38470	COG1405	negative regulation of cell septum assembly
pbN1_38520	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
pbN1_38540	COG0210	DNA helicase
pbN1_38600	COG4372	Transposase
pbN1_38710	COG0822	iron-sulfur transferase activity
pbN1_38720	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
pbN1_38730	COG0719	Fe-S assembly protein
pbN1_38740	COG0396	ATPase activity
pbN1_38750	COG0719	Fe-S assembly protein
pbN1_38760	COG1067	ATP-dependent peptidase activity
pbN1_38790	COG1881	PFAM PEBP family protein
pbN1_38870	COG0667	Aldo Keto reductase
pbN1_38980	COG2159	amidohydrolase
pbN1_39010	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
pbN1_39090	COG0438	transferase activity, transferring glycosyl groups
pbN1_39100	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
pbN1_39130	COG0438	transferase activity, transferring glycosyl groups
pbN1_39150	COG1215	transferase activity, transferring glycosyl groups
pbN1_39170	COG2327	Polysaccharide pyruvyl transferase
pbN1_39200	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
pbN1_39220	COG1196	nuclear chromosome segregation
pbN1_39240	COG2171	N-acyltransferase activity
pbN1_39260	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
pbN1_39280	COG0784	Response regulator, receiver
pbN1_39290	COG0386	Belongs to the glutathione peroxidase family
pbN1_39310	COG0633	Ferredoxin
pbN1_39320	COG0443	Heat shock 70 kDa protein
pbN1_39330	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
pbN1_39350	COG0822	iron-sulfur transferase activity
pbN1_39360	COG1104	cysteine desulfurase activity
pbN1_39370	COG1104	cysteine desulfurase activity
pbN1_39390	COG1045	serine acetyltransferase
pbN1_39410	COG0483	inositol monophosphate 1-phosphatase activity
pbN1_39430	COG0659	secondary active sulfate transmembrane transporter activity
pbN1_39440	COG0505	Belongs to the CarA family
pbN1_39450	COG2814	Major facilitator Superfamily
pbN1_39510	COG0107	imidazoleglycerol-phosphate synthase activity
pbN1_39540	COG0243	molybdopterin cofactor binding
pbN1_39590	COG3852	Histidine kinase
pbN1_39600	COG2204	response regulator
pbN1_39660	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
pbN1_39690	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
pbN1_39700	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
pbN1_39710	COG0022	dehydrogenase e1 component
pbN1_39710	COG0508	dehydrogenase complex catalyzes the overall conversion of
pbN1_39760	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
pbN1_39780	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
pbN1_39790	COG0328	RNA-DNA hybrid ribonuclease activity
pbN1_39800	COG2226	methyltransferase
pbN1_39810	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
pbN1_39820	COG0741	lytic transglycosylase activity
pbN1_39820	COG1388	LysM domain
pbN1_39830	COG4172	Belongs to the ABC transporter superfamily
pbN1_39850	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
pbN1_39860	COG2207	Transcriptional regulator
pbN1_39890	COG0745	RESPONSE REGULATOR receiver
pbN1_39900	COG2205	protein histidine kinase activity
pbN1_39920	COG0583	DNA-binding transcription factor activity
pbN1_39930	COG0477	Major facilitator Superfamily
pbN1_39940	COG1573	uracil-dna glycosylase
pbN1_39950	COG0456	acetyltransferase
pbN1_39960	COG1214	PFAM Peptidase M22, glycoprotease
pbN1_40000	COG2917	probably involved in intracellular septation
pbN1_40010	COG2350	Protein conserved in bacteria
pbN1_40030	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
pbN1_40040	COG1960	acyl-CoA dehydrogenase activity
pbN1_40080	COG1309	transcriptional regulator
pbN1_40090	COG0084	hydrolase, TatD family'
pbN1_40100	COG1024	Enoyl-CoA hydratase
pbN1_40110	COG0318	PFAM AMP-dependent synthetase and ligase
pbN1_40140	COG1127	ABC transporter
pbN1_40150	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
pbN1_40160	COG0248	Ppx GppA phosphatase
pbN1_40170	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
pbN1_40190	COG0629	single-stranded DNA binding
pbN1_40300	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
pbN1_40370	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
pbN1_40380	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
pbN1_40390	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
pbN1_40410	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
pbN1_40440	COG1355	regulation of microtubule-based process
pbN1_40450	COG2078	PFAM AMMECR1 domain protein
pbN1_40480	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
pbN1_40590	COG4680	protein conserved in bacteria
pbN1_40660	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
pbN1_40670	COG1022	Amp-dependent synthetase and ligase
pbN1_40700	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
pbN1_40720	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
pbN1_40720	COG1796	DNA polymerase
pbN1_40770	COG0518	GMP synthase (glutamine-hydrolyzing) activity
pbN1_40770	COG0519	Catalyzes the synthesis of GMP from XMP
pbN1_40800	COG2914	Belongs to the UPF0125 (RnfH) family
pbN1_40810	COG2867	negative regulation of translational initiation
pbN1_40820	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
pbN1_40830	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
pbN1_40850	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
pbN1_40860	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
pbN1_40870	COG0601	transmembrane transport
pbN1_40910	COG0542	response to heat
pbN1_40930	COG0314	molybdopterin synthase activity
pbN1_40940	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
pbN1_40950	COG0303	'Molybdopterin
pbN1_40960	COG1763	Mo-molybdopterin cofactor biosynthetic process
pbN1_40980	COG1199	ATP-dependent helicase activity
pbN1_41000	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
pbN1_41010	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
pbN1_41020	COG0508	dehydrogenase complex catalyzes the overall conversion of
pbN1_41030	COG0567	Dehydrogenase, E1 component
pbN1_41040	COG0372	Belongs to the citrate synthase family
pbN1_41060	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
pbN1_41070	COG1053	succinate dehydrogenase
pbN1_41100	COG2188	Transcriptional regulator
pbN1_41110	COG0039	L-malate dehydrogenase activity
pbN1_41130	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
pbN1_41160	COG1132	(ABC) transporter
pbN1_41170	COG3300	MHYT domain
pbN1_41170	COG5001	Diguanylate cyclase
pbN1_41180	COG0583	DNA-binding transcription factor activity
pbN1_41200	COG1804	L-carnitine dehydratase bile acid-inducible protein F
pbN1_41260	COG0183	Belongs to the thiolase family
pbN1_41300	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
pbN1_41470	COG4804	nuclease activity
pbN1_41550	COG4372	Transposase
pbN1_41560	COG1012	belongs to the aldehyde dehydrogenase family
pbN1_41580	COG2409	Drug exporters of the RND superfamily
pbN1_41620	COG3474	cytochrome
pbN1_41670	COG4584	PFAM Integrase catalytic
pbN1_41700	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
pbN1_41710	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
pbN1_41720	COG0183	Belongs to the thiolase family
pbN1_41730	COG1250	3-hydroxyacyl-CoA dehydrogenase
pbN1_41740	COG1960	acyl-CoA dehydrogenase activity
pbN1_41810	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
pbN1_41820	COG0427	acetyl-CoA hydrolase
pbN1_41870	COG1137	ATPase activity
pbN1_41880	COG0604	alcohol dehydrogenase
pbN1_41900	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
pbN1_41920	COG0318	PFAM AMP-dependent synthetase and ligase
pbN1_41930	COG1902	pentaerythritol trinitrate reductase activity
pbN1_41930	COG0446	pyridine nucleotide-disulphide oxidoreductase
pbN1_41940	COG1960	acyl-CoA dehydrogenase activity
pbN1_41950	COG1024	Enoyl-CoA hydratase
pbN1_41960	COG1846	Transcriptional regulator
pbN1_41970	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
pbN1_41990	COG0183	Belongs to the thiolase family
pbN1_42030	COG4566	intracellular signal transduction
pbN1_42040	COG0523	cobalamin synthesis protein