locus-tag	class	description
ADJ73_00010	COG0739	heme binding
ADJ73_00020	COG0752	glycyl-tRNA synthetase alpha subunit
ADJ73_00020	COG0751	glycine-tRNA ligase activity
ADJ73_00115	COG2197	response regulator
ADJ73_00135	COG1051	belongs to the nudix hydrolase family
ADJ73_00140	COG0438	transferase activity, transferring glycosyl groups
ADJ73_00145	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ADJ73_00160	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ADJ73_00190	COG0519	Catalyzes the synthesis of GMP from XMP
ADJ73_00190	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ADJ73_00210	COG1012	belongs to the aldehyde dehydrogenase family
ADJ73_00220	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ADJ73_00225	COG0516	GMP reductase activity
ADJ73_00240	COG1595	DNA-templated transcription, initiation
ADJ73_00245	COG2197	response regulator
ADJ73_00260	COG0459	protein refolding
ADJ73_00265	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ADJ73_00275	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ADJ73_00280	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ADJ73_00285	COG0456	acetyltransferase
ADJ73_00290	COG1214	PFAM Peptidase M22, glycoprotease
ADJ73_00290	COG0456	acetyltransferase
ADJ73_00305	COG0802	atpase or kinase
ADJ73_00315	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ADJ73_00325	COG0736	holo-[acyl-carrier-protein] synthase activity
ADJ73_00330	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ADJ73_00335	COG1072	(Pantothenic acid kinase))
ADJ73_00350	COG1918	ferrous iron import across plasma membrane
ADJ73_00350	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
ADJ73_00360	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ADJ73_00365	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ADJ73_00385	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ADJ73_00400	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ADJ73_00405	COG1487	ribonuclease activity
ADJ73_00440	COG0183	Belongs to the thiolase family
ADJ73_00460	COG0166	Belongs to the GPI family
ADJ73_00465	COG3033	Beta-eliminating lyase
ADJ73_00495	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ADJ73_00500	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ADJ73_00520	COG0148	phosphopyruvate hydratase activity
ADJ73_00545	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ADJ73_00550	COG1960	acyl-CoA dehydrogenase activity
ADJ73_00555	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ADJ73_00565	COG0193	aminoacyl-tRNA hydrolase activity
ADJ73_00570	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ADJ73_00575	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
ADJ73_00580	COG0736	holo-[acyl-carrier-protein] synthase activity
ADJ73_00590	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ADJ73_00595	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ADJ73_00600	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ADJ73_00620	COG1414	Transcriptional regulator
ADJ73_00625	COG1846	Transcriptional regulator
ADJ73_00640	COG0488	(ABC) transporter
ADJ73_00645	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ADJ73_00650	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ADJ73_00655	COG0084	hydrolase, TatD family'
ADJ73_00660	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ADJ73_00670	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ADJ73_00675	COG1053	succinate dehydrogenase
ADJ73_00690	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ADJ73_00710	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ADJ73_00715	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ADJ73_00720	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ADJ73_00745	COG0521	Mo-molybdopterin cofactor biosynthetic process
ADJ73_00750	COG0315	cyclic pyranopterin monophosphate synthase activity
ADJ73_00760	COG5001	Diguanylate cyclase
ADJ73_00760	COG2203	Gaf domain
ADJ73_00760	COG4251	negative regulation of phosphorylation
ADJ73_00760	COG3706	GGDEF domain
ADJ73_00765	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ADJ73_00790	COG1970	mechanosensitive ion channel activity
ADJ73_00805	COG3328	transposase activity
ADJ73_00825	COG1321	iron dependent repressor
ADJ73_00830	COG0259	pyridoxamine-phosphate oxidase activity
ADJ73_00845	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ADJ73_00855	COG1846	Transcriptional regulator
ADJ73_00860	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ADJ73_00865	COG2252	PERMEase
ADJ73_00885	COG1278	Cold shock
ADJ73_00900	COG0318	PFAM AMP-dependent synthetase and ligase
ADJ73_00910	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ADJ73_00915	COG1061	Type III restriction enzyme res subunit
ADJ73_00920	COG0745	RESPONSE REGULATOR receiver
ADJ73_00925	COG2205	protein histidine kinase activity
ADJ73_00930	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ADJ73_00935	COG3973	AAA domain
ADJ73_00965	COG0459	protein refolding
ADJ73_00985	COG2186	Transcriptional regulator
ADJ73_01000	COG0596	Alpha beta hydrolase
ADJ73_01005	COG0477	Major facilitator Superfamily
ADJ73_01015	COG3191	aminopeptidase activity
ADJ73_01025	COG1136	(ABC) transporter
ADJ73_01025	COG0577	efflux transmembrane transporter activity
ADJ73_01030	COG1136	(ABC) transporter
ADJ73_01035	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ADJ73_01050	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ADJ73_01055	COG1960	acyl-CoA dehydrogenase activity
ADJ73_01075	COG2022	thiamine diphosphate biosynthetic process
ADJ73_01075	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ADJ73_01085	COG2022	thiamine diphosphate biosynthetic process
ADJ73_01095	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ADJ73_01110	COG0442	prolyl-tRNA aminoacylation
ADJ73_01120	COG1132	(ABC) transporter
ADJ73_01130	COG3177	Filamentation induced by cAMP protein fic
ADJ73_01150	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ADJ73_01150	COG0515	serine threonine protein kinase
ADJ73_01160	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
ADJ73_01170	COG1609	Transcriptional regulator
ADJ73_01180	COG1175	transmembrane transport
ADJ73_01185	COG2182	Extracellular solute-binding protein
ADJ73_01190	COG3842	ATPase activity
ADJ73_01200	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ADJ73_01205	COG0215	cysteine-tRNA ligase activity
ADJ73_01215	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ADJ73_01220	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ADJ73_01235	COG0745	RESPONSE REGULATOR receiver
ADJ73_01240	COG5002	protein histidine kinase activity
ADJ73_01250	COG0588	phosphoglycerate mutase activity
ADJ73_01275	COG0738	Major facilitator superfamily
ADJ73_01290	COG1490	D-aminoacyl-tRNA deacylase activity
ADJ73_01305	COG3246	L-lysine catabolic process to acetate
ADJ73_01310	COG0354	folic acid binding
ADJ73_01320	COG4044	May play a role in the intracellular transport of hydrophobic ligands
ADJ73_01335	COG0745	RESPONSE REGULATOR receiver
ADJ73_01340	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ADJ73_01365	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ADJ73_01395	COG0039	L-malate dehydrogenase activity
ADJ73_01435	COG0297	glycogen (starch) synthase activity
ADJ73_01440	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ADJ73_01465	COG1028	Short-chain dehydrogenase reductase Sdr
ADJ73_01470	COG1793	dna ligase
ADJ73_01490	COG0415	Belongs to the DNA photolyase family
ADJ73_01495	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
ADJ73_01510	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
ADJ73_01550	COG1028	Short-chain dehydrogenase reductase Sdr
ADJ73_01630	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
ADJ73_01640	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ADJ73_01645	COG0667	Aldo Keto reductase
ADJ73_01650	COG1760	l-serine dehydratase
ADJ73_01655	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
ADJ73_01655	COG1796	DNA polymerase
ADJ73_01700	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ADJ73_01715	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ADJ73_01735	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
ADJ73_01740	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ADJ73_01740	COG0047	phosphoribosylformylglycinamidine synthase activity
ADJ73_01750	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ADJ73_01755	COG0151	Belongs to the GarS family
ADJ73_01765	COG0287	Prephenate dehydrogenase
ADJ73_01765	COG1605	Chorismate mutase
ADJ73_01770	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ADJ73_01785	COG0191	fructose-bisphosphate aldolase activity
ADJ73_01795	COG0586	Pfam SNARE associated Golgi protein
ADJ73_01805	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ADJ73_01815	COG0708	Exodeoxyribonuclease III
ADJ73_01825	COG0477	Major facilitator Superfamily
ADJ73_01835	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
ADJ73_01840	COG0352	thiamine-phosphate diphosphorylase activity
ADJ73_01845	COG0351	phosphomethylpyrimidine kinase
ADJ73_01850	COG0352	thiamine-phosphate diphosphorylase activity
ADJ73_01850	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
ADJ73_01850	COG0351	phosphomethylpyrimidine kinase
ADJ73_01855	COG1113	amino acid transport
ADJ73_01865	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ADJ73_01870	COG0542	response to heat
ADJ73_01895	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ADJ73_01905	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
ADJ73_01920	COG0789	Transcriptional regulator
ADJ73_01925	COG0484	heat shock protein binding
ADJ73_01930	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ADJ73_01935	COG0443	Heat shock 70 kDa protein
ADJ73_02005	COG0477	Major facilitator Superfamily
ADJ73_02030	COG0667	Aldo Keto reductase
ADJ73_02035	COG3387	PFAM Glycoside hydrolase 15-related
ADJ73_02045	COG1937	Protein conserved in bacteria
ADJ73_02085	COG0435	Glutathione S-transferase
ADJ73_02100	COG1643	Atp-dependent helicase
ADJ73_02130	COG1940	carbohydrate kinase activity
ADJ73_02150	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ADJ73_02170	COG1028	Short-chain dehydrogenase reductase Sdr
ADJ73_02175	COG0183	Belongs to the thiolase family
ADJ73_02190	COG1595	DNA-templated transcription, initiation
ADJ73_02195	COG2169	Transcriptional regulator
ADJ73_02195	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ADJ73_02200	COG2818	Glycosylase
ADJ73_02205	COG1022	Amp-dependent synthetase and ligase
ADJ73_02220	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ADJ73_02225	COG0584	glycerophosphoryl diester phosphodiesterase
ADJ73_02250	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ADJ73_02255	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ADJ73_02255	COG2190	(PTS) system
ADJ73_02255	COG1263	PTS System
ADJ73_02260	COG2188	Transcriptional regulator
ADJ73_02265	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ADJ73_02290	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ADJ73_02320	COG0436	Aminotransferase
ADJ73_02325	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ADJ73_02355	COG1929	Belongs to the glycerate kinase type-1 family
ADJ73_02380	COG0511	ligase activity, forming carbon-carbon bonds
ADJ73_02380	COG5016	pyruvate
ADJ73_02385	COG1802	Transcriptional regulator
ADJ73_02390	COG2515	1-aminocyclopropane-1-carboxylate deaminase
ADJ73_02400	COG0277	FAD linked oxidase domain protein
ADJ73_02405	COG0412	Dienelactone hydrolase
ADJ73_02410	COG2301	Belongs to the HpcH HpaI aldolase family
ADJ73_02415	COG2301	Belongs to the HpcH HpaI aldolase family
ADJ73_02420	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ADJ73_02420	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ADJ73_02450	COG0406	alpha-ribazole phosphatase activity
ADJ73_02485	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ADJ73_02510	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ADJ73_02525	COG0596	Alpha beta hydrolase
ADJ73_02535	COG0494	nUDIX hydrolase
ADJ73_02590	COG1408	metallophosphoesterase
ADJ73_02600	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ADJ73_02605	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ADJ73_02605	COG1017	nitric oxide dioxygenase activity
ADJ73_02620	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ADJ73_02635	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ADJ73_02635	COG2213	PTS system mannitol-specific
ADJ73_02640	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ADJ73_02645	COG0372	Belongs to the citrate synthase family
ADJ73_02650	COG0372	Belongs to the citrate synthase family
ADJ73_02670	COG0156	8-amino-7-oxononanoate synthase activity
ADJ73_02675	COG1819	glycosyl
ADJ73_02685	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ADJ73_02695	COG0318	PFAM AMP-dependent synthetase and ligase
ADJ73_02695	COG0204	Acyl-transferase
ADJ73_02705	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
ADJ73_02720	COG0433	COG0433 Predicted ATPase
ADJ73_02730	COG0366	Alpha amylase catalytic
ADJ73_02740	COG1024	Enoyl-CoA hydratase
ADJ73_02755	COG0590	tRNA wobble adenosine to inosine editing
ADJ73_02760	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ADJ73_02775	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
ADJ73_02780	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
ADJ73_02790	COG1122	ATPase activity
ADJ73_02800	COG0310	cobalt ion transport
ADJ73_02805	COG0531	amino acid
ADJ73_02830	COG0561	phosphatase activity
ADJ73_02835	COG0583	DNA-binding transcription factor activity
ADJ73_02855	COG2409	Drug exporters of the RND superfamily
ADJ73_02875	COG2837	iron assimilation
ADJ73_02885	COG0672	)-iron permease
ADJ73_02905	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
ADJ73_02950	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ADJ73_02955	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
ADJ73_02960	COG0297	glycogen (starch) synthase activity
ADJ73_03030	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
ADJ73_03040	COG0745	RESPONSE REGULATOR receiver
ADJ73_03045	COG2205	protein histidine kinase activity
ADJ73_03050	COG0662	Cupin 2, conserved barrel domain protein
ADJ73_03055	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ADJ73_03075	COG1278	Cold shock
ADJ73_03095	COG1045	serine acetyltransferase
ADJ73_03120	COG0717	Belongs to the dCTP deaminase family
ADJ73_03130	COG5001	Diguanylate cyclase
ADJ73_03135	COG1960	acyl-CoA dehydrogenase activity
ADJ73_03165	COG0529	Catalyzes the synthesis of activated sulfate
ADJ73_03170	COG0175	sulfate reduction
ADJ73_03180	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ADJ73_03190	COG1174	glycine betaine transport
ADJ73_03195	COG1174	glycine betaine transport
ADJ73_03200	COG1125	glycine betaine transport
ADJ73_03200	COG0517	IMP dehydrogenase activity
ADJ73_03225	COG2326	polyphosphate kinase activity
ADJ73_03270	COG0508	dehydrogenase complex catalyzes the overall conversion of
ADJ73_03275	COG0022	dehydrogenase e1 component
ADJ73_03290	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ADJ73_03295	COG1950	PFAM Membrane protein of
ADJ73_03350	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ADJ73_03370	COG3311	Transcriptional regulator
ADJ73_03375	COG1569	PIN domain
ADJ73_03380	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ADJ73_03385	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ADJ73_03410	COG2267	carboxylic ester hydrolase activity
ADJ73_03420	COG1250	3-hydroxyacyl-CoA dehydrogenase
ADJ73_03475	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ADJ73_03480	COG1271	oxidase subunit
ADJ73_03485	COG1294	oxidase, subunit
ADJ73_03490	COG4988	ABC transporter
ADJ73_03495	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ADJ73_03500	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ADJ73_03515	COG0488	(ABC) transporter
ADJ73_03565	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ADJ73_03575	COG4290	ribonuclease
ADJ73_03590	COG1937	Protein conserved in bacteria
ADJ73_03610	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ADJ73_03630	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ADJ73_03635	COG1803	Methylglyoxal synthase
ADJ73_03635	COG1597	lipid kinase activity
ADJ73_03640	COG0671	phosphoesterase, PA-phosphatase related
ADJ73_03655	COG3340	Belongs to the peptidase S51 family
ADJ73_03665	COG1668	transmembrane transport
ADJ73_03670	COG4152	abc transporter atp-binding protein
ADJ73_03675	COG2197	response regulator
ADJ73_03680	COG4585	Histidine kinase
ADJ73_03700	COG1215	transferase activity, transferring glycosyl groups
ADJ73_03730	COG0167	dihydroorotate dehydrogenase activity
ADJ73_03735	COG3237	CsbD-like
ADJ73_03750	COG1131	(ABC) transporter
ADJ73_03755	COG3559	Exporter of polyketide antibiotics
ADJ73_03775	COG2409	Drug exporters of the RND superfamily
ADJ73_03785	COG0431	NADPH-dependent FMN reductase
ADJ73_03795	COG1940	carbohydrate kinase activity
ADJ73_03795	COG1846	Transcriptional regulator
ADJ73_03815	COG0697	spore germination
ADJ73_03835	COG3851	Histidine kinase
ADJ73_03840	COG2197	response regulator
ADJ73_03850	COG0740	serine-type endopeptidase activity
ADJ73_03855	COG0740	serine-type endopeptidase activity
ADJ73_03860	COG1396	sequence-specific DNA binding
ADJ73_03870	COG1113	amino acid transport
ADJ73_03890	COG0477	Major facilitator Superfamily
ADJ73_03915	COG4941	Belongs to the sigma-70 factor family
ADJ73_03960	COG0702	epimerase
ADJ73_04015	COG3046	protein related to deoxyribodipyrimidine photolyase
ADJ73_04025	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
ADJ73_04050	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
ADJ73_04090	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ADJ73_04145	COG1414	Transcriptional regulator
ADJ73_04155	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ADJ73_04175	COG1846	Transcriptional regulator
ADJ73_04190	COG0179	Fumarylacetoacetate (FAA) hydrolase
ADJ73_04200	COG0549	Belongs to the carbamate kinase family
ADJ73_04205	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ADJ73_04210	COG2235	arginine
ADJ73_04230	COG0205	6-phosphofructokinase activity
ADJ73_04235	COG0018	arginyl-trna synthetase
ADJ73_04265	COG0351	phosphomethylpyrimidine kinase
ADJ73_04290	COG2132	Multicopper oxidase
ADJ73_04300	COG0745	RESPONSE REGULATOR receiver
ADJ73_04305	COG2205	protein histidine kinase activity
ADJ73_04335	COG1984	allophanate hydrolase subunit 2
ADJ73_04340	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
ADJ73_04365	COG1902	pentaerythritol trinitrate reductase activity
ADJ73_04380	COG0477	Major facilitator Superfamily
ADJ73_04390	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ADJ73_04410	COG4139	cobalamin transport
ADJ73_04455	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ADJ73_04460	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ADJ73_04465	COG0006	proline dipeptidase activity
ADJ73_04475	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ADJ73_04495	COG0189	ligase activity
ADJ73_04505	COG1823	symporter activity
ADJ73_04535	COG5001	Diguanylate cyclase
ADJ73_04535	COG3300	MHYT domain
ADJ73_04555	COG0500	methyltransferase
ADJ73_04575	COG1233	COG1233 Phytoene dehydrogenase and related
ADJ73_04585	COG2610	gluconate transmembrane transporter activity
ADJ73_04590	COG1028	Short-chain dehydrogenase reductase Sdr
ADJ73_04595	COG2130	NADP-dependent
ADJ73_04600	COG1764	response to oxidative stress
ADJ73_04605	COG1846	Transcriptional regulator
ADJ73_04730	COG1201	RNA secondary structure unwinding
ADJ73_04770	COG1129	ABC transporter
ADJ73_04780	COG1172	Belongs to the binding-protein-dependent transport system permease family
ADJ73_04815	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ADJ73_04910	COG1785	Belongs to the alkaline phosphatase family
ADJ73_04925	COG1968	undecaprenyl-diphosphatase activity
ADJ73_04935	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ADJ73_04995	COG1968	undecaprenyl-diphosphatase activity
ADJ73_05035	COG1454	alcohol dehydrogenase
ADJ73_05040	COG1072	(Pantothenic acid kinase))
ADJ73_05045	COG1733	regulation of RNA biosynthetic process
ADJ73_05050	COG2910	NAD(P)H-binding
ADJ73_05080	COG1716	ATPase activity
ADJ73_05095	COG0768	penicillin binding
ADJ73_05135	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ADJ73_05170	COG3266	domain, Protein
ADJ73_05175	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ADJ73_05180	COG0187	DNA topoisomerase II activity
ADJ73_05185	COG1289	transmembrane transporter activity
ADJ73_05210	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
ADJ73_05215	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ADJ73_05220	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
ADJ73_05225	COG0592	DNA-directed DNA polymerase activity
ADJ73_05230	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ADJ73_05235	COG0230	Belongs to the bacterial ribosomal protein bL34 family
ADJ73_05240	COG0594	ribonuclease P activity
ADJ73_05250	COG0706	membrane insertase activity
ADJ73_05265	COG1192	Involved in chromosome partitioning
ADJ73_05275	COG1181	Belongs to the D-alanine--D-alanine ligase family
ADJ73_05280	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ADJ73_05290	COG3118	belongs to the thioredoxin family
ADJ73_05305	COG1595	DNA-templated transcription, initiation
ADJ73_05330	COG0617	tRNA 3'-terminal CCA addition
ADJ73_05380	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ADJ73_05390	COG1260	myo-inositol-1-phosphate synthase
ADJ73_05405	COG0360	Binds together with S18 to 16S ribosomal RNA
ADJ73_05415	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ADJ73_05420	COG0359	binds to the 23S rRNA
ADJ73_05425	COG2188	Transcriptional regulator
ADJ73_05430	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ADJ73_05450	COG0673	inositol 2-dehydrogenase activity
ADJ73_05460	COG1486	melibiose metabolic process
ADJ73_05480	COG1175	transmembrane transport
ADJ73_05485	COG0395	ABC-type sugar transport system, permease component
ADJ73_05505	COG1280	lysine exporter protein (LysE YggA)
ADJ73_05510	COG2267	carboxylic ester hydrolase activity
ADJ73_05525	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ADJ73_05535	COG3718	enzyme involved in inositol metabolism
ADJ73_05550	COG1082	Xylose isomerase domain protein TIM barrel
ADJ73_05555	COG0673	inositol 2-dehydrogenase activity
ADJ73_05560	COG1082	Xylose isomerase domain protein TIM barrel
ADJ73_05565	COG0673	inositol 2-dehydrogenase activity
ADJ73_05580	COG1172	Belongs to the binding-protein-dependent transport system permease family
ADJ73_05595	COG2814	Major facilitator Superfamily
ADJ73_05600	COG1028	Short-chain dehydrogenase reductase Sdr
ADJ73_05615	COG0673	inositol 2-dehydrogenase activity
ADJ73_05620	COG0673	inositol 2-dehydrogenase activity
ADJ73_05635	COG0534	Mate efflux family protein
ADJ73_05765	COG5002	protein histidine kinase activity
ADJ73_05770	COG0745	RESPONSE REGULATOR receiver
ADJ73_05780	COG2132	Multicopper oxidase
ADJ73_05810	COG3328	transposase activity
ADJ73_05845	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ADJ73_05855	COG3467	pyridoxamine 5'-phosphate
ADJ73_05875	COG0179	Fumarylacetoacetate (FAA) hydrolase
ADJ73_05880	COG2186	Transcriptional regulator
ADJ73_05975	COG1250	3-hydroxyacyl-CoA dehydrogenase
ADJ73_05980	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ADJ73_05985	COG1024	Enoyl-CoA hydratase
ADJ73_05995	COG2814	Major facilitator Superfamily
ADJ73_06000	COG3485	protocatechuate 3,4-dioxygenase
ADJ73_06005	COG3485	protocatechuate 3,4-dioxygenase
ADJ73_06015	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ADJ73_06025	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ADJ73_06045	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
ADJ73_06060	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ADJ73_06065	COG2814	Major facilitator Superfamily
ADJ73_06115	COG1028	Short-chain dehydrogenase reductase Sdr
ADJ73_06140	COG2133	pyrroloquinoline quinone binding
ADJ73_06195	COG2197	response regulator
ADJ73_06200	COG3005	denitrification pathway
ADJ73_06215	COG0785	Cytochrome C biogenesis protein
ADJ73_06220	COG1333	cytochrome c biogenesis protein
ADJ73_06225	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ADJ73_06245	COG1253	flavin adenine dinucleotide binding
ADJ73_06295	COG0028	Belongs to the TPP enzyme family
ADJ73_06335	COG2353	YceI-like domain
ADJ73_06385	COG0626	cystathionine gamma-synthase activity
ADJ73_06400	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ADJ73_06440	COG0628	permease
ADJ73_06450	COG1960	acyl-CoA dehydrogenase activity
ADJ73_06455	COG1028	Short-chain dehydrogenase reductase Sdr
ADJ73_06470	COG1028	Short-chain dehydrogenase reductase Sdr
ADJ73_06500	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ADJ73_06505	COG1181	Belongs to the D-alanine--D-alanine ligase family
ADJ73_06535	COG0318	PFAM AMP-dependent synthetase and ligase
ADJ73_06540	COG3268	Saccharopine dehydrogenase
ADJ73_06585	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ADJ73_06605	COG0676	glucose-6-phosphate 1-epimerase activity
ADJ73_06615	COG2364	Membrane
ADJ73_06620	COG0765	amino acid transport
ADJ73_06625	COG0765	amino acid transport
ADJ73_06630	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ADJ73_06635	COG1126	abc transporter atp-binding protein
ADJ73_06665	COG1012	belongs to the aldehyde dehydrogenase family
ADJ73_06685	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ADJ73_06685	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ADJ73_06705	COG3025	triphosphatase activity
ADJ73_06705	COG5607	PFAM CHAD domain containing protein
ADJ73_06720	COG0579	oxidoreductase
ADJ73_06765	COG1136	(ABC) transporter
ADJ73_06765	COG0577	efflux transmembrane transporter activity
ADJ73_06775	COG1362	aminopeptidase activity
ADJ73_06805	COG2986	histidine ammonia-lyase
ADJ73_06815	COG0438	transferase activity, transferring glycosyl groups
ADJ73_06820	COG1278	Cold shock
ADJ73_06825	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
ADJ73_06830	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
ADJ73_06850	COG0693	protein deglycase activity
ADJ73_06865	COG2197	response regulator
ADJ73_06895	COG1228	amidohydrolase
ADJ73_06905	COG3851	Histidine kinase
ADJ73_06910	COG2197	response regulator
ADJ73_06915	COG1136	(ABC) transporter
ADJ73_06920	COG0577	efflux transmembrane transporter activity
ADJ73_06935	COG4721	ABC-type cobalt transport system, permease component
ADJ73_06940	COG1122	ATPase activity
ADJ73_07010	COG0776	regulation of translation
ADJ73_07015	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ADJ73_07020	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ADJ73_07030	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ADJ73_07040	COG2076	Multidrug Resistance protein
ADJ73_07050	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ADJ73_07060	COG3443	Belongs to the bacterial solute-binding protein 9 family
ADJ73_07060	COG0803	Belongs to the bacterial solute-binding protein 9 family
ADJ73_07070	COG2814	Major facilitator Superfamily
ADJ73_07075	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ADJ73_07085	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ADJ73_07100	COG3275	phosphorelay sensor kinase activity
ADJ73_07175	COG1111	helicase
ADJ73_07175	COG1205	dead DEAH box helicase
ADJ73_07185	COG2890	protein-(glutamine-N5) methyltransferase activity
ADJ73_07190	COG3384	dioxygenase
ADJ73_07195	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ADJ73_07195	COG1754	DNA topoisomerase type I activity
ADJ73_07205	COG0626	cystathionine gamma-synthase activity
ADJ73_07215	COG1131	(ABC) transporter
ADJ73_07220	COG0789	Transcriptional regulator
ADJ73_07235	COG1295	ribonuclease BN
ADJ73_07240	COG5001	Diguanylate cyclase
ADJ73_07240	COG5002	protein histidine kinase activity
ADJ73_07245	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ADJ73_07250	COG0470	DNA polymerase III
ADJ73_07290	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ADJ73_07295	COG2027	D-alanyl-D-alanine carboxypeptidase
ADJ73_07305	COG0037	tRNA processing
ADJ73_07315	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ADJ73_07320	COG0302	gtp cyclohydrolase
ADJ73_07330	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ADJ73_07350	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ADJ73_07370	COG0542	response to heat
ADJ73_07375	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
ADJ73_07390	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
ADJ73_07405	COG2226	methyltransferase
ADJ73_07415	COG0248	Ppx GppA phosphatase
ADJ73_07420	COG1082	Xylose isomerase domain protein TIM barrel
ADJ73_07450	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ADJ73_07460	COG0123	including yeast histone deacetylase and acetoin utilization protein
ADJ73_07495	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
ADJ73_07505	COG0181	hydroxymethylbilane synthase activity
ADJ73_07510	COG1648	precorrin-2 dehydrogenase activity
ADJ73_07510	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ADJ73_07515	COG0113	porphobilinogen synthase activity
ADJ73_07525	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ADJ73_07530	COG0406	alpha-ribazole phosphatase activity
ADJ73_07535	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ADJ73_07540	COG0785	Cytochrome C biogenesis protein
ADJ73_07550	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ADJ73_07605	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ADJ73_07615	COG1914	H( )-stimulated, divalent metal cation uptake system
ADJ73_07630	COG0861	Integral membrane protein TerC family
ADJ73_07640	COG2193	ferroxidase activity
ADJ73_07660	COG4948	Mandelate Racemase Muconate Lactonizing
ADJ73_07665	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
ADJ73_07685	COG3590	peptidase
ADJ73_07705	COG2226	methyltransferase
ADJ73_07720	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ADJ73_07725	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ADJ73_07730	COG0649	NAD binding
ADJ73_07745	COG1034	ATP synthesis coupled electron transport
ADJ73_07750	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ADJ73_07765	COG0713	ATP synthesis coupled electron transport
ADJ73_07770	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ADJ73_07780	COG1007	ATP synthesis coupled electron transport
ADJ73_07810	COG0501	Belongs to the peptidase M48B family
ADJ73_07825	COG1666	GTP binding
ADJ73_07845	COG0531	amino acid
ADJ73_07860	COG0281	malic enzyme
ADJ73_07865	COG0477	Major facilitator Superfamily
ADJ73_07870	COG0673	inositol 2-dehydrogenase activity
ADJ73_07875	COG1739	Uncharacterized protein family UPF0029
ADJ73_07880	COG3180	Ammonia monooxygenase
ADJ73_07885	COG1268	BioY protein
ADJ73_07890	COG1122	ATPase activity
ADJ73_07895	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ADJ73_07900	COG0205	6-phosphofructokinase activity
ADJ73_07930	COG1013	pyruvate-flavodoxin oxidoreductase activity
ADJ73_07950	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ADJ73_07955	COG2030	dehydratase
ADJ73_07965	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ADJ73_07970	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ADJ73_07975	COG2843	Capsule synthesis protein
ADJ73_07995	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ADJ73_08000	COG0081	regulation of translation
ADJ73_08010	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ADJ73_08015	COG0222	ribosome binding
ADJ73_08020	COG0085	RNA polymerase activity
ADJ73_08025	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ADJ73_08030	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ADJ73_08035	COG0049	tRNA binding
ADJ73_08040	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ADJ73_08050	COG1024	Enoyl-CoA hydratase
ADJ73_08065	COG0051	transcription antitermination factor activity, RNA binding
ADJ73_08070	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ADJ73_08075	COG0088	Forms part of the polypeptide exit tunnel
ADJ73_08080	COG0089	rRNA binding
ADJ73_08085	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ADJ73_08090	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ADJ73_08095	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ADJ73_08100	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ADJ73_08105	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ADJ73_08110	COG0255	Belongs to the universal ribosomal protein uL29 family
ADJ73_08115	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ADJ73_08120	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ADJ73_08125	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ADJ73_08130	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ADJ73_08140	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ADJ73_08145	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ADJ73_08150	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ADJ73_08155	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ADJ73_08160	COG1841	ribosomal large subunit assembly
ADJ73_08165	COG0200	Binds to the 23S rRNA
ADJ73_08175	COG0563	adenylate kinase activity
ADJ73_08185	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ADJ73_08190	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ADJ73_08195	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ADJ73_08200	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ADJ73_08210	COG0202	RNA polymerase activity
ADJ73_08215	COG0203	ribosomal protein L17
ADJ73_08220	COG0101	tRNA pseudouridine synthase activity
ADJ73_08240	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ADJ73_08245	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ADJ73_08250	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ADJ73_08255	COG1522	sequence-specific DNA binding
ADJ73_08270	COG0508	dehydrogenase complex catalyzes the overall conversion of
ADJ73_08305	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
ADJ73_08305	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
ADJ73_08315	COG1653	transport
ADJ73_08320	COG1175	transmembrane transport
ADJ73_08325	COG0395	ABC-type sugar transport system, permease component
ADJ73_08330	COG1653	transport
ADJ73_08345	COG1722	exodeoxyribonuclease VII activity
ADJ73_08350	COG1570	exodeoxyribonuclease VII activity
ADJ73_08380	COG5012	cobalamin binding
ADJ73_08390	COG3457	Alanine racemase
ADJ73_08395	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ADJ73_08435	COG1131	(ABC) transporter
ADJ73_08440	COG1322	Protein conserved in bacteria
ADJ73_08455	COG0012	GTP binding
ADJ73_08480	COG4716	Myosin-crossreactive antigen
ADJ73_08490	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ADJ73_08510	COG4585	Histidine kinase
ADJ73_08525	COG4667	esterase of the alpha-beta hydrolase superfamily
ADJ73_08530	COG3511	phospholipase C
ADJ73_08535	COG0833	amino acid
ADJ73_08545	COG0129	dihydroxy-acid dehydratase activity
ADJ73_08565	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
ADJ73_08580	COG0494	nUDIX hydrolase
ADJ73_08595	COG4166	transmembrane transport
ADJ73_08610	COG4608	Belongs to the ABC transporter superfamily
ADJ73_08615	COG2326	polyphosphate kinase activity
ADJ73_08620	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ADJ73_08630	COG2720	vancomycin resistance protein
ADJ73_08660	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ADJ73_08665	COG1611	Belongs to the LOG family
ADJ73_08680	COG1024	Enoyl-CoA hydratase
ADJ73_08690	COG1595	DNA-templated transcription, initiation
ADJ73_08710	COG2239	Acts as a magnesium transporter
ADJ73_08730	COG1960	acyl-CoA dehydrogenase activity
ADJ73_08740	COG0006	proline dipeptidase activity
ADJ73_08750	COG2030	dehydratase
ADJ73_08755	COG0613	PHP domain protein
ADJ73_08765	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ADJ73_08770	COG0513	Belongs to the DEAD box helicase family
ADJ73_08845	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ADJ73_08855	COG1024	Enoyl-CoA hydratase
ADJ73_08880	COG3480	Lon protease (S16) C-terminal proteolytic domain
ADJ73_08890	COG1615	UPF0182 protein
ADJ73_08920	COG0612	Peptidase, M16
ADJ73_08930	COG0483	inositol monophosphate 1-phosphatase activity
ADJ73_08935	COG0671	phosphoesterase, PA-phosphatase related
ADJ73_08940	COG1162	GTPase activity
ADJ73_08945	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ADJ73_08950	COG2135	peptidase activity
ADJ73_08955	COG1595	DNA-templated transcription, initiation
ADJ73_08960	COG5662	AntiSigma factor
ADJ73_08995	COG0508	dehydrogenase complex catalyzes the overall conversion of
ADJ73_08995	COG0567	Dehydrogenase, E1 component
ADJ73_09000	COG1253	flavin adenine dinucleotide binding
ADJ73_09010	COG0778	Nitroreductase
ADJ73_09010	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
ADJ73_09045	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ADJ73_09050	COG2835	tetraacyldisaccharide 4'-kinase activity
ADJ73_09060	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
ADJ73_09085	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ADJ73_09090	COG2197	response regulator
ADJ73_09095	COG3214	Protein conserved in bacteria
ADJ73_09100	COG0653	protein targeting
ADJ73_09130	COG1192	Involved in chromosome partitioning
ADJ73_09135	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ADJ73_09160	COG2902	Dehydrogenase
ADJ73_09180	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ADJ73_09235	COG2186	Transcriptional regulator
ADJ73_09240	COG3265	gluconokinase activity
ADJ73_09250	COG1129	ABC transporter
ADJ73_09255	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ADJ73_09280	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ADJ73_09290	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
ADJ73_09295	COG0477	Major facilitator Superfamily
ADJ73_09325	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ADJ73_09330	COG0513	Belongs to the DEAD box helicase family
ADJ73_09335	COG1678	Uncharacterized ACR, COG1678
ADJ73_09360	COG3185	4-Hydroxyphenylpyruvate dioxygenase
ADJ73_09385	COG1335	isochorismatase
ADJ73_09400	COG1012	belongs to the aldehyde dehydrogenase family
ADJ73_09410	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
ADJ73_09425	COG0765	amino acid transport
ADJ73_09440	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ADJ73_09445	COG1234	tRNA 3'-trailer cleavage
ADJ73_09460	COG2409	Drug exporters of the RND superfamily
ADJ73_09465	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ADJ73_09470	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ADJ73_09475	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ADJ73_09510	COG3858	chitin binding
ADJ73_09510	COG1388	LysM domain
ADJ73_09550	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
ADJ73_09585	COG0737	Belongs to the 5'-nucleotidase family
ADJ73_09630	COG1946	Acyl-CoA thioesterase
ADJ73_09640	COG0514	ATP-dependent DNA helicase (RecQ)
ADJ73_09675	COG0668	transmembrane transport
ADJ73_09685	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ADJ73_09690	COG0765	amino acid transport
ADJ73_09705	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
ADJ73_09710	COG0698	ribose 5-phosphate isomerase
ADJ73_09730	COG0183	Belongs to the thiolase family
ADJ73_09740	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ADJ73_09755	COG0740	serine-type endopeptidase activity
ADJ73_09760	COG0740	serine-type endopeptidase activity
ADJ73_09765	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ADJ73_09780	COG0714	Associated with various cellular activities
ADJ73_09805	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ADJ73_09810	COG0525	valine-tRNA ligase activity
ADJ73_09825	COG1619	proteins homologs of microcin C7 resistance protein MccF
ADJ73_09835	COG0277	FAD linked oxidase domain protein
ADJ73_09840	COG0427	acetyl-CoA hydrolase
ADJ73_09850	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ADJ73_09855	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ADJ73_09860	COG0285	dihydrofolate synthase activity
ADJ73_09870	COG0105	UTP biosynthetic process
ADJ73_09885	COG1966	Carbon starvation protein
ADJ73_09900	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ADJ73_09905	COG1185	polyribonucleotide nucleotidyltransferase activity
ADJ73_09920	COG0277	FAD linked oxidase domain protein
ADJ73_09925	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ADJ73_09930	COG1556	Lactate utilization protein
ADJ73_09940	COG0247	lactate metabolic process
ADJ73_09945	COG1620	l-lactate permease
ADJ73_09950	COG2186	Transcriptional regulator
ADJ73_09960	COG3396	Phenylacetate-CoA oxygenase
ADJ73_09965	COG3460	Phenylacetate-CoA oxygenase
ADJ73_09970	COG3396	Phenylacetate-CoA oxygenase
ADJ73_09975	COG2151	metal-sulfur cluster biosynthetic enzyme
ADJ73_09980	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ADJ73_09995	COG1930	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
ADJ73_10000	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ADJ73_10020	COG0779	Required for maturation of 30S ribosomal subunits
ADJ73_10045	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ADJ73_10060	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ADJ73_10075	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ADJ73_10080	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ADJ73_10085	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ADJ73_10160	COG0247	lactate metabolic process
ADJ73_10160	COG0277	FAD linked oxidase domain protein
ADJ73_10165	COG0730	response to heat
ADJ73_10175	COG1136	(ABC) transporter
ADJ73_10185	COG1530	ribonuclease E activity
ADJ73_10190	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ADJ73_10195	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ADJ73_10200	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ADJ73_10205	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ADJ73_10210	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ADJ73_10215	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ADJ73_10230	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ADJ73_10250	COG0495	leucyl-tRNA aminoacylation
ADJ73_10255	COG1307	EDD domain protein, DegV family
ADJ73_10265	COG0658	competence protein
ADJ73_10265	COG2333	competence protein COMEC
ADJ73_10270	COG0583	DNA-binding transcription factor activity
ADJ73_10275	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ADJ73_10290	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ADJ73_10310	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ADJ73_10315	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ADJ73_10330	COG0800	Aldolase
ADJ73_10340	COG2271	Major facilitator Superfamily
ADJ73_10350	COG1609	Transcriptional regulator
ADJ73_10355	COG1129	ABC transporter
ADJ73_10360	COG1172	Belongs to the binding-protein-dependent transport system permease family
ADJ73_10365	COG1879	ABC-type sugar transport system periplasmic component
ADJ73_10375	COG1869	D-ribose catabolic process
ADJ73_10385	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
ADJ73_10390	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ADJ73_10390	COG1263	PTS System
ADJ73_10395	COG1960	acyl-CoA dehydrogenase activity
ADJ73_10410	COG4607	ABC-type enterochelin transport system periplasmic component
ADJ73_10415	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ADJ73_10420	COG4605	iron ion homeostasis
ADJ73_10425	COG4604	ABC transporter, ATP-binding protein
ADJ73_10440	COG1063	alcohol dehydrogenase
ADJ73_10475	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ADJ73_10495	COG0444	Belongs to the ABC transporter superfamily
ADJ73_10500	COG4608	Belongs to the ABC transporter superfamily
ADJ73_10505	COG0174	glutamine synthetase
ADJ73_10520	COG1022	Amp-dependent synthetase and ligase
ADJ73_10525	COG1022	Amp-dependent synthetase and ligase
ADJ73_10550	COG1643	Atp-dependent helicase
ADJ73_10605	COG0589	response to stress
ADJ73_10610	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ADJ73_10615	COG1305	Transglutaminase-like
ADJ73_10625	COG0714	Associated with various cellular activities
ADJ73_10630	COG2001	Belongs to the MraZ family
ADJ73_10635	COG0275	rRNA processing
ADJ73_10655	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ADJ73_10660	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ADJ73_10670	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ADJ73_10675	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ADJ73_10685	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ADJ73_10700	COG1799	cell septum assembly
ADJ73_10720	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ADJ73_10730	COG0587	DNA-directed DNA polymerase activity
ADJ73_10745	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
ADJ73_10755	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ADJ73_10795	COG0542	response to heat
ADJ73_10800	COG0390	transport system, permease component
ADJ73_10810	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ADJ73_10815	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ADJ73_10820	COG0131	Imidazoleglycerol-phosphate dehydratase
ADJ73_10830	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ADJ73_10840	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ADJ73_10865	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
ADJ73_10870	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ADJ73_10875	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ADJ73_10880	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ADJ73_10885	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ADJ73_10890	COG5002	protein histidine kinase activity
ADJ73_10895	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ADJ73_10900	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ADJ73_10900	COG0072	phenylalanine-tRNA ligase activity
ADJ73_10905	COG1028	Short-chain dehydrogenase reductase Sdr
ADJ73_10910	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ADJ73_10915	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ADJ73_10920	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ADJ73_10925	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ADJ73_10930	COG1438	arginine binding
ADJ73_10935	COG0165	Argininosuccinate lyase
ADJ73_10950	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ADJ73_10980	COG0647	UMP catabolic process
ADJ73_10995	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ADJ73_11000	COG0497	DNA recombination
ADJ73_11030	COG0504	CTP synthase activity
ADJ73_11040	COG3012	SEC-C Motif Domain Protein
ADJ73_11075	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ADJ73_11095	COG0444	Belongs to the ABC transporter superfamily
ADJ73_11100	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ADJ73_11105	COG0601	transmembrane transport
ADJ73_11140	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ADJ73_11145	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ADJ73_11150	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ADJ73_11155	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ADJ73_11160	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ADJ73_11170	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ADJ73_11175	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ADJ73_11185	COG2197	response regulator
ADJ73_11190	COG4585	Histidine kinase
ADJ73_11195	COG1131	(ABC) transporter
ADJ73_11205	COG0425	Belongs to the sulfur carrier protein TusA family
ADJ73_11210	COG2391	methyltransferase activity
ADJ73_11215	COG0069	glutamate synthase activity
ADJ73_11220	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ADJ73_11225	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ADJ73_11235	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
ADJ73_11240	COG0540	Belongs to the ATCase OTCase family
ADJ73_11245	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ADJ73_11250	COG0505	Belongs to the CarA family
ADJ73_11255	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ADJ73_11260	COG0284	orotidine-5'-phosphate decarboxylase activity
ADJ73_11270	COG0194	GDP metabolic process
ADJ73_11275	COG1758	RNA polymerase activity
ADJ73_11285	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ADJ73_11300	COG0242	peptide deformylase activity
ADJ73_11305	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ADJ73_11315	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ADJ73_11320	COG0140	phosphoribosyl-ATP diphosphatase activity
ADJ73_11325	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ADJ73_11335	COG1482	cell wall glycoprotein biosynthetic process
ADJ73_11340	COG2233	PERMEase
ADJ73_11345	COG4129	membrane
ADJ73_11355	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ADJ73_11355	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ADJ73_11365	COG0107	imidazoleglycerol-phosphate synthase activity
ADJ73_11380	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ADJ73_11410	COG0134	indole-3-glycerol-phosphate synthase activity
ADJ73_11415	COG0133	tryptophan synthase activity
ADJ73_11420	COG0159	tryptophan synthase activity
ADJ73_11435	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ADJ73_11440	COG0069	glutamate synthase activity
ADJ73_11440	COG0070	glutamate synthase
ADJ73_11440	COG0067	glutamate synthase
ADJ73_11450	COG0469	pyruvate kinase activity
ADJ73_11475	COG2050	protein possibly involved in aromatic compounds catabolism
ADJ73_11485	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ADJ73_11485	COG2111	Na H antiporter
ADJ73_11515	COG2759	Belongs to the formate--tetrahydrofolate ligase family
ADJ73_11525	COG2226	methyltransferase
ADJ73_11530	COG0539	negative regulation of cytoplasmic translation
ADJ73_11545	COG0237	dephospho-CoA kinase activity
ADJ73_11545	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
ADJ73_11550	COG0556	nucleotide-excision repair
ADJ73_11555	COG0861	Integral membrane protein TerC family
ADJ73_11560	COG5006	permease, DMT superfamily
ADJ73_11575	COG1063	alcohol dehydrogenase
ADJ73_11580	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ADJ73_11590	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ADJ73_11600	COG0410	ABC transporter
ADJ73_11605	COG0411	ABC transporter
ADJ73_11625	COG0322	excinuclease ABC activity
ADJ73_11630	COG1660	Displays ATPase and GTPase activities
ADJ73_11640	COG1481	regulation of sporulation
ADJ73_11645	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ADJ73_11650	COG0126	phosphoglycerate kinase activity
ADJ73_11655	COG0149	triose-phosphate isomerase activity
ADJ73_11680	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ADJ73_11695	COG1793	dna ligase
ADJ73_11705	COG2326	polyphosphate kinase activity
ADJ73_11740	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ADJ73_11775	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ADJ73_11785	COG2873	o-acetylhomoserine
ADJ73_11795	COG2095	MarC family integral membrane protein
ADJ73_11825	COG2119	membrane
ADJ73_11860	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
ADJ73_11870	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ADJ73_11880	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
ADJ73_11885	COG0217	transcriptional regulatory protein
ADJ73_11890	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ADJ73_11895	COG0632	four-way junction helicase activity
ADJ73_11900	COG2255	four-way junction helicase activity
ADJ73_11910	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ADJ73_11915	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ADJ73_11920	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ADJ73_11925	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ADJ73_11940	COG1131	(ABC) transporter
ADJ73_11960	COG1196	nuclear chromosome segregation
ADJ73_11965	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ADJ73_11975	COG0124	histidyl-tRNA synthetase
ADJ73_11985	COG2318	DinB family
ADJ73_12000	COG0686	Belongs to the AlaDH PNT family
ADJ73_12025	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ADJ73_12040	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ADJ73_12060	COG1160	GTP binding
ADJ73_12105	COG1136	(ABC) transporter
ADJ73_12105	COG0577	efflux transmembrane transporter activity
ADJ73_12145	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ADJ73_12160	COG0667	Aldo Keto reductase
ADJ73_12170	COG0114	fumarate hydratase activity
ADJ73_12180	COG0673	inositol 2-dehydrogenase activity
ADJ73_12210	COG0509	glycine decarboxylation via glycine cleavage system
ADJ73_12215	COG1716	ATPase activity
ADJ73_12235	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ADJ73_12235	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ADJ73_12270	COG0420	3'-5' exonuclease activity
ADJ73_12280	COG0588	phosphoglycerate mutase activity
ADJ73_12320	COG1355	regulation of microtubule-based process
ADJ73_12335	COG0564	pseudouridine synthase activity
ADJ73_12360	COG0596	Alpha beta hydrolase
ADJ73_12375	COG1595	DNA-templated transcription, initiation
ADJ73_12390	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ADJ73_12395	COG3609	addiction module antidote protein, CC2985 family
ADJ73_12400	COG2337	Toxic component of a toxin-antitoxin (TA) module
ADJ73_12420	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ADJ73_12430	COG1131	(ABC) transporter
ADJ73_12435	COG1309	transcriptional regulator
ADJ73_12445	COG0477	Major facilitator Superfamily
ADJ73_12475	COG2270	Major facilitator Superfamily
ADJ73_12490	COG1216	Glycosyl transferase, family 2
ADJ73_12500	COG1607	acyl-coa hydrolase
ADJ73_12505	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ADJ73_12510	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ADJ73_12520	COG0604	alcohol dehydrogenase
ADJ73_12525	COG1509	lysine 2,3-aminomutase activity
ADJ73_12530	COG0583	DNA-binding transcription factor activity
ADJ73_12535	COG4948	Mandelate Racemase Muconate Lactonizing
ADJ73_12540	COG3485	protocatechuate 3,4-dioxygenase
ADJ73_12545	COG4829	muconolactone delta-isomerase
ADJ73_12550	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ADJ73_12555	COG0183	Belongs to the thiolase family
ADJ73_12560	COG1522	sequence-specific DNA binding
ADJ73_12565	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ADJ73_12585	COG0477	Major facilitator Superfamily
ADJ73_12595	COG0805	protein transport
ADJ73_12600	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ADJ73_12620	COG0439	Biotin carboxylase
ADJ73_12665	COG4122	O-methyltransferase activity
ADJ73_12675	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ADJ73_12690	COG1222	aaa ATPase
ADJ73_12700	COG0517	IMP dehydrogenase activity
ADJ73_12700	COG1994	Peptidase M50
ADJ73_12715	COG0546	phosphoglycolate phosphatase activity
ADJ73_12720	COG0646	methionine synthase
ADJ73_12720	COG1410	methionine synthase
ADJ73_12730	COG0215	cysteine-tRNA ligase activity
ADJ73_12750	COG0598	Magnesium transport protein CorA
ADJ73_12765	COG1968	undecaprenyl-diphosphatase activity
ADJ73_12780	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ADJ73_12790	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ADJ73_12850	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ADJ73_12865	COG1132	(ABC) transporter
ADJ73_12870	COG1881	PFAM PEBP family protein
ADJ73_12885	COG0477	Major facilitator Superfamily
ADJ73_12885	COG2814	Major facilitator Superfamily
ADJ73_12910	COG1119	ATPase activity
ADJ73_12920	COG0297	glycogen (starch) synthase activity
ADJ73_12925	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ADJ73_12930	COG0560	Phosphoserine phosphatase
ADJ73_12930	COG3830	Belongs to the UPF0237 family
ADJ73_12940	COG0189	ligase activity
ADJ73_12940	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ADJ73_12950	COG0488	(ABC) transporter
ADJ73_12960	COG1028	Short-chain dehydrogenase reductase Sdr
ADJ73_12975	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ADJ73_12985	COG1132	(ABC) transporter
ADJ73_12990	COG1024	Enoyl-CoA hydratase
ADJ73_12995	COG0488	(ABC) transporter
ADJ73_13025	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ADJ73_13025	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ADJ73_13030	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ADJ73_13050	COG2151	metal-sulfur cluster biosynthetic enzyme
ADJ73_13055	COG0822	iron-sulfur transferase activity
ADJ73_13065	COG0396	ATPase activity
ADJ73_13075	COG0719	Fe-S assembly protein
ADJ73_13105	COG0109	protoheme IX farnesyltransferase activity
ADJ73_13115	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ADJ73_13130	COG0363	glucosamine-6-phosphate deaminase activity
ADJ73_13140	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ADJ73_13145	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ADJ73_13155	COG2197	response regulator
ADJ73_13165	COG0183	Belongs to the thiolase family
ADJ73_13170	COG1250	3-hydroxyacyl-CoA dehydrogenase
ADJ73_13170	COG1024	Enoyl-CoA hydratase
ADJ73_13180	COG2354	Protein conserved in bacteria
ADJ73_13185	COG0583	DNA-binding transcription factor activity
ADJ73_13190	COG3634	alkyl hydroperoxide reductase activity
ADJ73_13195	COG0450	alkyl hydroperoxide reductase
ADJ73_13200	COG0339	signal peptide processing
ADJ73_13205	COG0546	phosphoglycolate phosphatase activity
ADJ73_13210	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ADJ73_13240	COG1175	transmembrane transport
ADJ73_13245	COG0395	ABC-type sugar transport system, permease component
ADJ73_13255	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ADJ73_13270	COG0569	domain protein
ADJ73_13295	COG0756	dUTP diphosphatase activity
ADJ73_13315	COG2860	membrane
ADJ73_13330	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ADJ73_13330	COG0574	Belongs to the PEP-utilizing enzyme family
ADJ73_13340	COG1435	thymidine kinase activity
ADJ73_13360	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ADJ73_13360	COG0045	succinate-CoA ligase (ADP-forming) activity
ADJ73_13360	COG1042	CoA-binding domain protein
ADJ73_13375	COG0778	Nitroreductase
ADJ73_13380	COG1349	DNA-binding transcription factor activity
ADJ73_13390	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ADJ73_13390	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ADJ73_13390	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ADJ73_13400	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ADJ73_13405	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ADJ73_13410	COG0456	acetyltransferase
ADJ73_13415	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ADJ73_13425	COG0531	amino acid
ADJ73_13455	COG2264	protein methyltransferase activity
ADJ73_13460	COG0587	DNA-directed DNA polymerase activity
ADJ73_13500	COG2815	serine threonine protein kinase
ADJ73_13500	COG0515	serine threonine protein kinase
ADJ73_13505	COG0697	spore germination
ADJ73_13515	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
ADJ73_13555	COG1940	carbohydrate kinase activity
ADJ73_13560	COG1940	carbohydrate kinase activity
ADJ73_13600	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ADJ73_13610	COG1845	cytochrome c oxidase, subunit III
ADJ73_13615	COG2010	Cytochrome c
ADJ73_13620	COG0723	plastoquinol--plastocyanin reductase activity
ADJ73_13625	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ADJ73_13655	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ADJ73_13660	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ADJ73_13665	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
ADJ73_13695	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ADJ73_13710	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ADJ73_13710	COG1648	precorrin-2 dehydrogenase activity
ADJ73_13715	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
ADJ73_13725	COG1797	cobyrinic acid a,c-diamide synthase activity
ADJ73_13765	COG2318	DinB family
ADJ73_13780	COG2813	Specifically methylates the guanine in position
ADJ73_13790	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
ADJ73_13790	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ADJ73_13825	COG1492	cobalamin metabolic process
ADJ73_13855	COG3845	ABC transporter
ADJ73_13870	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
ADJ73_13880	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ADJ73_13885	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ADJ73_13890	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ADJ73_13895	COG0508	dehydrogenase complex catalyzes the overall conversion of
ADJ73_13925	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ADJ73_13940	COG0174	glutamine synthetase
ADJ73_13965	COG3051	citrate lyase alpha subunit
ADJ73_13975	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
ADJ73_13980	COG1597	lipid kinase activity
ADJ73_13990	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
ADJ73_13995	COG0174	glutamine synthetase
ADJ73_14045	COG0557	exoribonuclease II activity
ADJ73_14050	COG3022	response to hydroperoxide
ADJ73_14055	COG0328	RNA-DNA hybrid ribonuclease activity
ADJ73_14055	COG0406	alpha-ribazole phosphatase activity
ADJ73_14085	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ADJ73_14090	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ADJ73_14095	COG3328	transposase activity
ADJ73_14115	COG0584	glycerophosphoryl diester phosphodiesterase
ADJ73_14130	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ADJ73_14135	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ADJ73_14190	COG0358	DNA primase activity
ADJ73_14195	COG0232	Belongs to the dGTPase family. Type 2 subfamily
ADJ73_14225	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ADJ73_14235	COG0431	NADPH-dependent FMN reductase
ADJ73_14240	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ADJ73_14275	COG0137	argininosuccinate synthase activity
ADJ73_14280	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ADJ73_14285	COG1381	Involved in DNA repair and RecF pathway recombination
ADJ73_14305	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ADJ73_14330	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ADJ73_14340	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ADJ73_14350	COG0537	adenosine 5'-monophosphoramidase activity
ADJ73_14365	COG0484	heat shock protein binding
ADJ73_14370	COG1420	regulation of RNA biosynthetic process
ADJ73_14395	COG2855	membrane
ADJ73_14415	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ADJ73_14420	COG0481	GTPase activity
ADJ73_14425	COG2814	Major facilitator Superfamily
ADJ73_14435	COG0268	Binds directly to 16S ribosomal RNA
ADJ73_14455	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ADJ73_14460	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ADJ73_14465	COG2226	methyltransferase
ADJ73_14475	COG0477	Major facilitator Superfamily
ADJ73_14490	COG0456	acetyltransferase
ADJ73_14515	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ADJ73_14535	COG1297	OPT oligopeptide transporter protein
ADJ73_14540	COG2813	Specifically methylates the guanine in position
ADJ73_14545	COG0405	Gamma-glutamyltransferase
ADJ73_14550	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ADJ73_14570	COG0697	spore germination
ADJ73_14580	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ADJ73_14585	COG2807	transmembrane transport
ADJ73_14600	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ADJ73_14605	COG3304	Inner membrane component domain
ADJ73_14610	COG2137	regulation of response to DNA damage stimulus
ADJ73_14615	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ADJ73_14635	COG1201	RNA secondary structure unwinding
ADJ73_14650	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ADJ73_14660	COG1058	Belongs to the CinA family
ADJ73_14660	COG1546	Belongs to the CinA family
ADJ73_14670	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ADJ73_14680	COG1674	ftsk spoiiie
ADJ73_14700	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ADJ73_14705	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ADJ73_14740	COG0442	prolyl-tRNA aminoacylation
ADJ73_14765	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ADJ73_14770	COG0750	zinc metalloprotease
ADJ73_14775	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ADJ73_14790	COG1177	transmembrane transport
ADJ73_14795	COG1176	ABC-type spermidine putrescine transport system, permease component I
ADJ73_14825	COG0586	Pfam SNARE associated Golgi protein
ADJ73_14830	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ADJ73_14835	COG0575	Belongs to the CDS family
ADJ73_14840	COG0233	cytoplasmic translational termination
ADJ73_14845	COG0528	UMP kinase activity
ADJ73_14850	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ADJ73_14855	COG0052	Belongs to the universal ribosomal protein uS2 family
ADJ73_14875	COG4974	Belongs to the 'phage' integrase family
ADJ73_14885	COG0606	chelatase, subunit chli
ADJ73_14890	COG0792	nuclease activity
ADJ73_14905	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ADJ73_14910	COG0681	Belongs to the peptidase S26 family
ADJ73_14920	COG0335	large ribosomal subunit rRNA binding
ADJ73_14925	COG0336	Belongs to the RNA methyltransferase TrmD family
ADJ73_14930	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ADJ73_14935	COG1837	Belongs to the UPF0109 family
ADJ73_14940	COG0228	four-way junction DNA binding
ADJ73_14960	COG4213	ABC transporter substrate-binding protein
ADJ73_14965	COG1172	Belongs to the binding-protein-dependent transport system permease family
ADJ73_14975	COG1940	carbohydrate kinase activity
ADJ73_15005	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
ADJ73_15030	COG1196	nuclear chromosome segregation
ADJ73_15035	COG1254	Belongs to the acylphosphatase family
ADJ73_15055	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ADJ73_15065	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ADJ73_15075	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ADJ73_15080	COG0742	ribosomal rna small subunit methyltransferase
ADJ73_15095	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ADJ73_15140	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ADJ73_15160	COG0776	regulation of translation
ADJ73_15165	COG0066	3-isopropylmalate dehydratase activity
ADJ73_15170	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ADJ73_15180	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ADJ73_15190	COG0427	acetyl-CoA hydrolase
ADJ73_15220	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ADJ73_15225	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ADJ73_15230	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ADJ73_15235	COG0179	Fumarylacetoacetate (FAA) hydrolase
ADJ73_15250	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ADJ73_15255	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
ADJ73_15260	COG1028	Short-chain dehydrogenase reductase Sdr
ADJ73_15265	COG1012	belongs to the aldehyde dehydrogenase family
ADJ73_15285	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ADJ73_15290	COG0473	3-isopropylmalate dehydrogenase activity
ADJ73_15305	COG1921	L-seryl-tRNASec selenium transferase activity
ADJ73_15330	COG0709	Synthesizes selenophosphate from selenide and ATP
ADJ73_15355	COG0437	4 iron, 4 sulfur cluster binding
ADJ73_15360	COG3383	formate dehydrogenase (NAD+) activity
ADJ73_15360	COG0243	molybdopterin cofactor binding
ADJ73_15365	COG3383	formate dehydrogenase (NAD+) activity
ADJ73_15365	COG0243	molybdopterin cofactor binding
ADJ73_15385	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ADJ73_15410	COG1511	domain protein
ADJ73_15410	COG1511	domain protein
ADJ73_15450	COG1473	amidohydrolase
ADJ73_15460	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ADJ73_15465	COG0154	amidase activity
ADJ73_15470	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ADJ73_15475	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ADJ73_15480	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ADJ73_15490	COG0697	spore germination
ADJ73_15500	COG0482	sulfurtransferase activity
ADJ73_15515	COG0754	glutathionylspermidine amidase activity
ADJ73_15525	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
ADJ73_15550	COG0058	SHG alpha-glucan phosphorylase activity
ADJ73_15555	COG0366	Alpha amylase catalytic
ADJ73_15560	COG0366	Alpha amylase catalytic
ADJ73_15580	COG0483	inositol monophosphate 1-phosphatase activity
ADJ73_15610	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ADJ73_15610	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ADJ73_15635	COG0183	Belongs to the thiolase family
ADJ73_15680	COG1250	3-hydroxyacyl-CoA dehydrogenase
ADJ73_15685	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
ADJ73_15720	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ADJ73_15740	COG0463	Glycosyl transferase, family 2
ADJ73_15750	COG0297	glycogen (starch) synthase activity
ADJ73_15750	COG0438	transferase activity, transferring glycosyl groups
ADJ73_15755	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ADJ73_15760	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ADJ73_15765	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ADJ73_15770	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ADJ73_15775	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ADJ73_15780	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ADJ73_15785	COG0356	it plays a direct role in the translocation of protons across the membrane
ADJ73_15800	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ADJ73_15805	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ADJ73_15815	COG2890	protein-(glutamine-N5) methyltransferase activity
ADJ73_15820	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ADJ73_15825	COG0254	rRNA binding
ADJ73_15835	COG1215	transferase activity, transferring glycosyl groups
ADJ73_15855	COG0083	homoserine kinase activity
ADJ73_15860	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ADJ73_15865	COG0460	homoserine dehydrogenase
ADJ73_15870	COG0019	diaminopimelate decarboxylase activity
ADJ73_15880	COG0745	RESPONSE REGULATOR receiver
ADJ73_15910	COG2385	sporulation resulting in formation of a cellular spore
ADJ73_15935	COG1216	Glycosyl transferase, family 2
ADJ73_15955	COG1316	TRANSCRIPTIONal
ADJ73_15960	COG1216	Glycosyl transferase, family 2
ADJ73_15965	COG1216	Glycosyl transferase, family 2
ADJ73_15990	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ADJ73_16000	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ADJ73_16020	COG1024	Enoyl-CoA hydratase
ADJ73_16035	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ADJ73_16050	COG0025	NhaP-type Na H and K H
ADJ73_16060	COG0424	maF-like protein
ADJ73_16065	COG0789	Transcriptional regulator
ADJ73_16070	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ADJ73_16075	COG1960	acyl-CoA dehydrogenase activity
ADJ73_16100	COG4770	biotin carboxylase activity
ADJ73_16105	COG0693	protein deglycase activity
ADJ73_16130	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ADJ73_16155	COG0714	Associated with various cellular activities
ADJ73_16160	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
ADJ73_16175	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ADJ73_16185	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ADJ73_16185	COG0662	Cupin 2, conserved barrel domain protein
ADJ73_16195	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ADJ73_16205	COG3135	benzoate transporter
ADJ73_16270	COG1473	amidohydrolase
ADJ73_16285	COG0438	transferase activity, transferring glycosyl groups
ADJ73_16290	COG1686	Belongs to the peptidase S11 family
ADJ73_16300	COG0180	Tryptophanyl-tRNA synthetase
ADJ73_16310	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
ADJ73_16365	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ADJ73_16385	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ADJ73_16395	COG0138	bifunctional purine biosynthesis protein purh
ADJ73_16420	COG0045	succinate-CoA ligase (ADP-forming) activity