locus-tag	class	description
MB46_00035	ENOG4105ETE	Transcriptional regulator (LacI family
MB46_00040	ENOG4105CG3	alpha amylase, catalytic region
MB46_00050	ENOG4105D56	permease protein
MB46_00055	ENOG4105EG2	ABC transporter, permease
MB46_00060	ENOG4107R28	alpha amylase, catalytic region
MB46_00065	ENOG4105CQB	FAD linked oxidase domain protein
MB46_00075	ENOG4108IJ9	(ABC) transporter
MB46_00080	ENOG4105DZC	cytosine deaminase
MB46_00090	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
MB46_00140	ENOG4105ETE	Transcriptional regulator (LacI family
MB46_00150	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
MB46_00155	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
MB46_00165	ENOG4108JQ7	(ABC) transporter
MB46_00185	ENOG4108535	NAD dependent epimerase/dehydratase family
MB46_00210	ENOG4105ETE	Transcriptional regulator (LacI family
MB46_00230	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
MB46_00235	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
MB46_00260	ENOG4105ETE	Transcriptional regulator (LacI family
MB46_00290	ENOG4108HRG	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity)
MB46_00295	ENOG4105C26	Dehydrogenase
MB46_00300	ENOG4105CJK	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity)
MB46_00305	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
MB46_00310	ENOG4105F0H	myo-inositol catabolism protein
MB46_00315	ENOG4107QNK	)-transporter
MB46_00320	ENOG4105DH8	myo-inositol catabolism
MB46_00325	ENOG4108X79	transcriptional regulator
MB46_00340	ENOG4105CG3	alpha amylase, catalytic region
MB46_00360	ENOG4105ETE	Transcriptional regulator (LacI family
MB46_00365	ENOG4105BZ1	(ABC) transporter
MB46_00370	ENOG4105BZ1	(ABC) transporter
MB46_00395	ENOG4105DQ5	transport system permease protein
MB46_00400	ENOG4105TVJ	transport system, permease
MB46_00405	ENOG4105E0A	ABC, transporter
MB46_00430	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
MB46_00440	ENOG4105ETE	Transcriptional regulator (LacI family
MB46_00445	ENOG4108HKT	sucrose-6-phosphate hydrolase
MB46_00450	ENOG4108HKT	sucrose-6-phosphate hydrolase
MB46_00475	ENOG4105CPC	Aldo Keto reductase
MB46_00500	ENOG4108IJ0	Aspartate ammonia-lyase
MB46_00510	ENOG4105D6E	homoserine dehydrogenase
MB46_00515	ENOG4108IQI	permease
MB46_00530	ENOG4107HP6	Transcriptional regulator
MB46_00545	ENOG4107QK5	Homocysteine s-methyltransferase
MB46_00555	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
MB46_00570	ENOG4106PVI	ATP-dependent carboxylate-amine ligase (By similarity)
MB46_00615	ENOG4107SIG	periplasmic solute binding protein
MB46_00630	ENOG4105FDK	ABC transporter
MB46_00635	ENOG4107STQ	Multicopper oxidase
MB46_00640	ENOG4105CHH	sulfate transporter
MB46_00665	ENOG4107TE5	Lipid kinase
MB46_00690	ENOG4107RRE	RNA-directed DNA polymerase
MB46_00700	ENOG4105BZ1	(ABC) transporter
MB46_00705	ENOG4105BZ1	(ABC) transporter
MB46_00725	ENOG4105E2R	ROK family
MB46_00730	ENOG4105KNR	Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity)
MB46_00735	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
MB46_00745	ENOG4108JQ5	ABC transporter
MB46_00750	ENOG4108JQ6	ABC transporter
MB46_00760	ENOG4105ETE	Transcriptional regulator (LacI family
MB46_00765	ENOG4105CID	antiterminator
MB46_00775	ENOG4105C5Y	PTS System
MB46_00780	ENOG4108X4Q	Hydrolase
MB46_00785	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
MB46_00830	ENOG4105C26	Dehydrogenase
MB46_00840	ENOG4105E39	Enoyl-CoA hydratase
MB46_00850	ENOG4105E5Q	amino acid AbC transporter
MB46_00875	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
MB46_00880	ENOG4107RBB	ABC transporter, permease
MB46_00900	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
MB46_00920	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
MB46_00935	ENOG4105BZU	Histidine kinase
MB46_00940	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
MB46_00955	ENOG4105C1J	atp-dependent rna helicase
MB46_00980	ENOG4107R8H	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
MB46_00990	ENOG4105DR5	peptidase
MB46_01000	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
MB46_01015	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
MB46_01025	ENOG4105CDA	abc transporter atp-binding protein
MB46_01030	ENOG4105DRP	amino acid AbC transporter
MB46_01040	ENOG4105BZ1	(ABC) transporter
MB46_01065	ENOG4108MWI	inositol mono-phosphatase
MB46_01080	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
MB46_01100	ENOG4105F27	Major Facilitator
MB46_01105	ENOG4105CV8	reductase
MB46_01110	ENOG41082J7	Rhodanese domain protein
MB46_01150	ENOG4108JCI	Transcriptional regulator
MB46_01165	ENOG4105C7K	acetolactate synthase
MB46_01170	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
MB46_01220	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
MB46_01235	ENOG4105ECP	epimerase
MB46_01250	ENOG4107YCY	Transcriptional regulator
MB46_01260	ENOG4108IJ0	Aspartate ammonia-lyase
MB46_01290	ENOG4105CMT	Dihydroxyacetone kinase
MB46_01295	ENOG4107YVI	ribose 5-phosphate isomerase
MB46_01300	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
MB46_01310	ENOG4105CSP	Major Facilitator Superfamily
MB46_01315	ENOG4105CP7	Triose-phosphate isomerase
MB46_01335	ENOG4108ZEY	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
MB46_01340	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
MB46_01375	ENOG4105ETE	Transcriptional regulator (LacI family
MB46_01380	ENOG4108HWW	ABC transporter
MB46_01390	ENOG4105DFW	ABC transporter
MB46_01400	ENOG4105C93	Xylose Isomerase
MB46_01405	ENOG4105E2R	ROK family
MB46_01505	ENOG4105E98	transcriptional regulator DeoR family
MB46_01520	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
MB46_01535	ENOG4108JU3	Alkyl hydroperoxide reductase
MB46_01555	ENOG4105CSU	acyl-Coa dehydrogenase
MB46_01570	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
MB46_01580	ENOG4105VEQ	Cold shock protein
MB46_01615	ENOG4105C54	Major Facilitator superfamily
MB46_01620	ENOG4105DTQ	mandelate racemase muconate lactonizing
MB46_01630	ENOG4107S1E	Beta-lactamase
MB46_01635	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
MB46_01645	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
MB46_01655	ENOG4108J59	Extracellular solute-binding protein, family 5
MB46_01670	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MB46_01675	ENOG4106KNT	transcriptional regulator
MB46_01680	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
MB46_01685	ENOG4105DC1	bifunctional purine biosynthesis protein purh
MB46_01700	ENOG4105E9K	Isocitrate dehydrogenase
MB46_01715	ENOG4105C32	Amino acid ABC transporter (Permease)
MB46_01720	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
MB46_01725	ENOG4105C0Z	ABC transporter
MB46_01730	ENOG4108IV0	ABC, transporter
MB46_01750	ENOG4105DFW	ABC transporter
MB46_01755	ENOG4107RNG	ABC transporter
MB46_01785	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
MB46_01790	ENOG4105CUB	amino acid
MB46_01800	ENOG4105CPC	Aldo Keto reductase
MB46_01805	ENOG4105C5A	transporter
MB46_01810	ENOG4105CFM	UPF0317 protein
MB46_01820	ENOG4108JIK	carboxylase
MB46_01825	ENOG4107R7A	Allophanate hydrolase subunit 2
MB46_01830	ENOG4105E7W	lamb ycsf family protein
MB46_01840	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
MB46_01845	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
MB46_01855	ENOG4105D4Y	metalloprotease
MB46_01870	ENOG4105WH1	Two component transcriptional regulator luxr family
MB46_01895	ENOG4105C31	Tryptophanyl-tRNA synthetase
MB46_01915	ENOG4105E33	succinate dehydrogenase
MB46_01935	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
MB46_01940	ENOG4107RM1	amidohydrolase
MB46_01945	ENOG4105DIH	basic membrane
MB46_01950	ENOG4108JQ9	ABC transporter
MB46_01955	ENOG4105UIB	(ABC) transporter
MB46_01975	ENOG4107XFB	conserved TRANSMEMBRANE PROTEIN
MB46_01980	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
MB46_02000	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
MB46_02050	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
MB46_02060	ENOG4105E98	transcriptional regulator DeoR family
MB46_02065	ENOG4107WI4	Aldose-1-epimerase
MB46_02075	ENOG4105C7B	Threonine dehydratase
MB46_02085	ENOG4107YD5	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
MB46_02095	ENOG4105T1M	mycothiol conjugate amidase mca
MB46_02105	ENOG4105C7Z	Conserved Protein
MB46_02115	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
MB46_02120	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
MB46_02130	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
MB46_02135	ENOG4108IAB	Phoh family
MB46_02160	ENOG4108V9W	transcriptional regulatory protein
MB46_02165	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
MB46_02170	ENOG4105D4T	Citrate transporter
MB46_02190	ENOG4105C9Q	fumarate hydratase class II
MB46_02195	ENOG4108V9Q	carbonic anhydrase
MB46_02220	ENOG4105EIP	mannose-6-phosphate isomerase
MB46_02225	ENOG4108KGH	TRANSCRIPTIONal
MB46_02250	ENOG4105K51	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
MB46_02255	ENOG4107RGC	Glycosyl transferase, family 2
MB46_02280	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
MB46_02335	ENOG4107QMS	site-determining protein
MB46_02410	ENOG4105F8V	Hydrolase, tatD family
MB46_02415	ENOG4106839	domain protein
MB46_02420	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
MB46_02425	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
MB46_02430	ENOG4105C5H	ABC transporter
MB46_02445	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
MB46_02460	ENOG4107XT7	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
MB46_02465	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
MB46_02480	ENOG41086KC	Transcriptional regulator
MB46_02485	ENOG4108KX4	response regulator
MB46_02490	ENOG4107QQG	Dehydrogenase
MB46_02495	ENOG4108IAJ	Nad-dependent epimerase dehydratase
MB46_02510	ENOG4108NNZ	chitinase
MB46_02535	ENOG41090RK	glycosyl transferase
MB46_02545	ENOG4108UNV	SUF system FeS assembly protein, NifU family
MB46_02560	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
MB46_02575	ENOG4105C30	Nad-dependent epimerase dehydratase
MB46_02580	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
MB46_02585	ENOG4106CD9	glycosyl transferase group 1
MB46_02600	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
MB46_02620	ENOG4105BZU	Histidine kinase
MB46_02625	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
MB46_02630	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
MB46_02660	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
MB46_02690	ENOG4105BZU	Histidine kinase
MB46_02725	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
MB46_02735	ENOG4105EXC	Acyl-transferase
MB46_02740	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
MB46_02745	ENOG4107QZF	nitrite reductase NADPH large subunit
MB46_02755	ENOG4107QSU	Phosphoglucomutase phosphomannomutase alpha beta alpha domain
MB46_02770	ENOG4108IFG	nitrite reductase, (NAD(P)H)
MB46_02775	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
MB46_02780	ENOG4107QND	Nitrite extrusion protein
MB46_02785	ENOG4105CSH	Transporter
MB46_02790	ENOG4108JIK	carboxylase
MB46_02805	ENOG4107WR6	Maf-like protein
MB46_02825	ENOG4105C26	Dehydrogenase
MB46_02830	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
MB46_02835	ENOG4107RR1	TRANSCRIPTIONal
MB46_02840	ENOG4105EYF	MMPL domain protein
MB46_02865	ENOG4107Y2X	deaminase
MB46_02870	ENOG4108ETY	sodium dicarboxylate symporter
MB46_02885	ENOG4105D8K	carboxyl transferase
MB46_02905	ENOG4105WH1	Two component transcriptional regulator luxr family
MB46_02920	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
MB46_02960	ENOG4105EC2	ftsk spoIIIe
MB46_02970	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
MB46_02985	ENOG4105CG3	alpha amylase, catalytic region
MB46_02990	ENOG4105I1K	ABC transporter
MB46_02995	ENOG4105EQ7	Binding-protein-dependent transport systems, inner membrane component
MB46_03005	ENOG4105DKQ	ROK family
MB46_03025	ENOG4108176	endoribonuclease L-psp
MB46_03035	ENOG41081AP	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
MB46_03040	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
MB46_03045	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
MB46_03070	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
MB46_03080	ENOG4105ETE	Transcriptional regulator (LacI family
MB46_03085	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
MB46_03095	ENOG4105CPQ	Dehydrogenase
MB46_03100	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
MB46_03110	ENOG4105E6M	Sulphatase-modifying factor protein
MB46_03115	ENOG4108NIW	Leucine export protein LeuE
MB46_03120	ENOG4105CI2	imidazolone-5-propionate hydrolase
MB46_03125	ENOG4105ESP	cell wall surface anchor family protein
MB46_03135	ENOG4105EZX	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity)
MB46_03150	ENOG4105E98	transcriptional regulator DeoR family
MB46_03155	ENOG4105DBE	peroxidase
MB46_03165	ENOG4105EKT	)-iron permease
MB46_03170	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
MB46_03190	ENOG4105BZM	domain protein
MB46_03195	ENOG4108IQK	o-acetylhomoserine
MB46_03200	ENOG4105DWV	Homoserine O-trans-acetylase
MB46_03235	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
MB46_03255	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
MB46_03260	ENOG41065KQ	synthase
MB46_03270	ENOG4105CJW	magnesium transporter
MB46_03280	ENOG4105ECB	domain protein
MB46_03285	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
MB46_03295	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
MB46_03305	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
MB46_03340	ENOG4105CPK	Glycosyl transferase (Group 1
MB46_03355	ENOG4105C2C	drug resistance transporter, Bcr CflA
MB46_03375	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
MB46_03480	ENOG4105C1G	acyl-Coa dehydrogenase
MB46_03490	ENOG4105CE9	30S ribosomal protein S2
MB46_03495	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
MB46_03500	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
MB46_03505	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
MB46_03530	ENOG4105DY9	regulatoR
MB46_03535	ENOG4108HRK	Histidine kinase
MB46_03545	ENOG4107QN1	sodium solute
MB46_03560	ENOG4105EW9	transcriptional regulator AsnC family
MB46_03570	ENOG4105CPP	Dehydrogenase, E1 component
MB46_03575	ENOG4107RN0	branched-chain alpha-keto acid dehydrogenase subunit E2
MB46_03590	ENOG4107QX3	carboxylase
MB46_03600	ENOG4105C1G	acyl-Coa dehydrogenase
MB46_03635	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
MB46_03640	ENOG4105DZP	Membrane-associated zinc metalloprotease
MB46_03645	ENOG4105ETE	Transcriptional regulator (LacI family
MB46_03650	ENOG4108HKT	sucrose-6-phosphate hydrolase
MB46_03655	ENOG4105EDQ	levansucrase EC 2.4.1.10
MB46_03680	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
MB46_03690	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
MB46_03710	ENOG4105CIG	ABC transporter
MB46_03720	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
MB46_03745	ENOG4107Z1I	Required for maturation of 30S ribosomal subunits (By similarity)
MB46_03755	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
MB46_03760	ENOG4107ZPY	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
MB46_03780	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
MB46_03805	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
MB46_03810	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
MB46_03815	ENOG4105C1V	Peptidase, M16
MB46_03845	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
MB46_03850	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
MB46_03860	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
MB46_03870	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
MB46_03875	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
MB46_03880	ENOG4105CN5	Metallo-Beta-Lactamase
MB46_03885	ENOG4107QZI	cell division protein FtsK
MB46_03895	ENOG4105CEV	competence damage-inducible protein
MB46_03910	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
MB46_03915	ENOG4105KC9	Modulates RecA activity (By similarity)
MB46_03925	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
MB46_03930	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
MB46_03935	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
MB46_03940	ENOG4107Y49	methyltransferase
MB46_03945	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
MB46_03955	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
MB46_03965	ENOG4105CIH	Imidazole acetol-phosphate transaminase
MB46_03970	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
MB46_03975	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
MB46_03980	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
MB46_04000	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
MB46_04005	ENOG41084BS	50S ribosomal protein L35
MB46_04010	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
MB46_04015	ENOG4108RWN	rrna methyltransferase
MB46_04020	ENOG4105F27	Major Facilitator
MB46_04040	ENOG4105CEY	Amp-dependent synthetase and ligase
MB46_04060	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
MB46_04065	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
MB46_04095	ENOG4105CSR	polyphosphate kinase 2
MB46_04115	ENOG4105CEY	Amp-dependent synthetase and ligase
MB46_04130	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
MB46_04135	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
MB46_04140	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
MB46_04145	ENOG4105CAS	nag kinase
MB46_04150	ENOG4105C8Y	Acetylornithine aminotransferase
MB46_04155	ENOG4105DBV	ornithine carbamoyltransferase
MB46_04160	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
MB46_04165	ENOG4105CDH	Citrulline--aspartate ligase
MB46_04170	ENOG4105CH7	arginosuccinase
MB46_04190	ENOG4108VX5	3-methyladenine DNA glycosylase
MB46_04200	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
MB46_04210	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
MB46_04245	ENOG4105DSU	hydrolase
MB46_04265	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
MB46_04270	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
MB46_04290	ENOG4105KME	endoribonuclease L-psp
MB46_04295	ENOG4107258	Transcriptional regulator
MB46_04320	ENOG4105C6Z	Gluconate
MB46_04330	ENOG4107HP6	Transcriptional regulator
MB46_04335	ENOG4105E2D	ec 3.2.1.52
MB46_04340	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
MB46_04370	ENOG4105CR4	methylisocitrate lyase
MB46_04385	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
MB46_04390	ENOG4108FUT	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
MB46_04395	ENOG4105DUU	IucA IucC family protein
MB46_04405	ENOG4105F1Y	L-lysine 6-monooxygenase (NADPH)
MB46_04415	ENOG4108MRH	transcriptional regulatory protein
MB46_04425	ENOG4107QJT	sodium dicarboxylate symporter
MB46_04445	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
MB46_04450	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
MB46_04465	ENOG4105CAT	Cytidine monophosphate kinase
MB46_04475	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
MB46_04505	ENOG4105EVE	HAD-superfamily hydrolase subfamily IA variant 3
MB46_04530	ENOG4105CV8	reductase
MB46_04535	ENOG4107RHR	regulatoR
MB46_04545	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
MB46_04550	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
MB46_04555	ENOG4105C8T	Leucyl-tRNA synthetase
MB46_04560	ENOG4105EPR	degv family
MB46_04580	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
MB46_04590	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
MB46_04595	ENOG4105CSA	Coproporphyrinogen iii oxidase
MB46_04610	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
MB46_04615	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
MB46_04635	ENOG4107VNR	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
MB46_04645	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
MB46_04650	ENOG4107TB5	TRANSCRIPTIONal
MB46_04655	ENOG4105C9K	Endothelin-converting enzyme 1
MB46_04660	ENOG4107QXN	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
MB46_04665	ENOG4106DBE	Involved in DNA repair and RecF pathway recombination (By similarity)
MB46_04670	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
MB46_04685	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
MB46_04690	ENOG4105CPC	Aldo Keto reductase
MB46_04700	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
MB46_04710	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
MB46_04715	ENOG4105BZ9	Cytochrome C oxidase, subunit I
MB46_04720	ENOG4108ZRS	Part of cytochrome c oxidase, its function is
MB46_04730	ENOG4105FDP	GntR family transcriptional regulator
MB46_04735	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
MB46_04740	ENOG4107EUI	c reductase, iron-sulfur
MB46_04745	ENOG4107UDY	cytochrome C
MB46_04750	ENOG4105CCU	oxidase (Subunit III)
MB46_04755	ENOG4108I0Q	anthranilate phosphoribosyltransferase
MB46_04785	ENOG4108ESY	Metal dependent phosphohydrolase
MB46_04800	ENOG4105DZ6	Band 7 protein
MB46_04805	ENOG4105C7B	Threonine dehydratase
MB46_04820	ENOG4105CQ7	ATP-dependent helicase
MB46_04825	ENOG4105DPV	During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co- crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2 ) ion and storing it in the form of Fe(3 ) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2 ) ions, which prevents hydroxyl radical production by the Fenton reaction
MB46_04830	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
MB46_04875	ENOG4105D8V	Glucose sorbosone dehydrogenase
MB46_04890	ENOG4105CHH	sulfate transporter
MB46_04900	ENOG4105CEY	Amp-dependent synthetase and ligase
MB46_04915	ENOG4105DEN	Luciferase family
MB46_04920	ENOG4105EUB	pirin domain protein
MB46_04935	ENOG4105KA0	thioesterase Superfamily protein
MB46_04945	ENOG4105HHS	UPF0256 protein
MB46_04950	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
MB46_04955	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
MB46_04970	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
MB46_04975	ENOG4107QM2	Aldo Keto reductase
MB46_04995	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
MB46_05015	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
MB46_05020	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
MB46_05035	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
MB46_05040	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
MB46_05050	ENOG4105CIE	May be required for sporulation (By similarity)
MB46_05055	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
MB46_05060	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
MB46_05065	ENOG4105BZA	Phosphoglycerate kinase
MB46_05070	ENOG4105CP7	Triose-phosphate isomerase
MB46_05080	ENOG4107XU2	6-phosphogluconolactonase (EC 3.1.1.31)
MB46_05095	ENOG4105C89	phosphohexose isomerase
MB46_05100	ENOG4107QQX	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
MB46_05110	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
MB46_05125	ENOG4105CJ1	ABC, transporter
MB46_05150	ENOG4105C3K	feS assembly ATPase SufC
MB46_05155	ENOG4105VG1	fes assembly suf system protein
MB46_05170	ENOG4105CHU	acetyl-coa acetyltransferase
MB46_05175	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
MB46_05180	ENOG4108JJB	ABC transporter
MB46_05185	ENOG4107ZYJ	bioY protein
MB46_05190	ENOG4105C5H	ABC transporter
MB46_05215	ENOG4105CHR	reductase
MB46_05220	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
MB46_05225	ENOG4105EAC	phosphoserine phosphatase
MB46_05230	ENOG4105DKW	ABC transporter
MB46_05250	ENOG4105NRA	50s ribosomal protein l31 type b
MB46_05270	ENOG4107ZR7	Membrane
MB46_05280	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
MB46_05285	ENOG4107QPH	glycogen) synthase
MB46_05315	ENOG4105CHU	acetyl-coa acetyltransferase
MB46_05320	ENOG4105CHR	reductase
MB46_05340	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
MB46_05360	ENOG4105CV8	reductase
MB46_05365	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
MB46_05370	ENOG4105C8N	cysteinyl-tRNA synthetase
MB46_05380	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
MB46_05395	ENOG4105DHM	ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis (By similarity)
MB46_05400	ENOG4105E5F	proteasome
MB46_05405	ENOG4105WFD	Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation (By similarity)
MB46_05410	ENOG4105KPK	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (By similarity)
MB46_05415	ENOG4105F7N	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (By similarity)
MB46_05420	ENOG4105DVV	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine (By similarity)
MB46_05425	ENOG4108V1T	peptidylprolyl cis-trans isomerase
MB46_05450	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
MB46_05455	ENOG4105CQR	helicase
MB46_05460	ENOG4105EFZ	amidohydrolase
MB46_05465	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
MB46_05490	ENOG4108VW9	Membrane
MB46_05500	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
MB46_05520	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
MB46_05525	ENOG4108YIQ	Alpha beta hydrolase
MB46_05580	ENOG41061CK	Antibiotic biosynthesis monooxygenase
MB46_05595	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
MB46_05640	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
MB46_05645	ENOG4105E2R	ROK family
MB46_05660	ENOG4107UWC	ABC, transporter
MB46_05665	ENOG4105CBG	Sulfatase
MB46_05690	ENOG4105EW9	transcriptional regulator AsnC family
MB46_05700	ENOG4105DIK	(ABC) transporter
MB46_05720	ENOG4105C5I	Dehydrogenase
MB46_05740	ENOG4105E98	transcriptional regulator DeoR family
MB46_05745	ENOG4105CH2	amidohydrolase
MB46_05760	ENOG4105PW4	Sugar fermentation stimulation protein homolog
MB46_05785	ENOG4105CPQ	Dehydrogenase
MB46_05790	ENOG4105S7S	phosphonate abc transporter
MB46_05800	ENOG4106ZX3	phosphonate ABC transporter, periplasmic phosphonate-binding protein
MB46_05815	ENOG4108IQI	permease
MB46_05825	ENOG4105D9G	High-affinity
MB46_05830	ENOG4105ICD	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
MB46_05835	ENOG4107S16	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
MB46_05840	ENOG4108YH3	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
MB46_05845	ENOG4105HFU	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity)
MB46_05850	ENOG4105CQM	Urea amidohydrolase subunit alpha
MB46_05855	ENOG4105KI2	Urea amidohydrolase subunit beta
MB46_05860	ENOG4108YZ9	Urea amidohydrolase subunit gamma
MB46_05870	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
MB46_05930	ENOG4105CH2	amidohydrolase
MB46_05935	ENOG4105C94	Transporter
MB46_05945	ENOG4105K4P	CoA-binding domain protein
MB46_05955	ENOG4105FBW	Monooxygenase
MB46_05960	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
MB46_05985	ENOG4105DRS	transport system, permease
MB46_06000	ENOG4105ETE	Transcriptional regulator (LacI family
MB46_06005	ENOG4105ETE	Transcriptional regulator (LacI family
MB46_06010	ENOG4105XN3	extracellular solute-binding protein family 1
MB46_06015	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
MB46_06035	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
MB46_06040	ENOG4105QE3	oxidoreductase
MB46_06045	ENOG4105K56	Transcriptional regulator
MB46_06050	ENOG4108ZHJ	Organic hydroperoxide resistance protein
MB46_06060	ENOG4108MES	Periplasmic binding protein
MB46_06065	ENOG4105DQ5	transport system permease protein
MB46_06070	ENOG4105TVJ	transport system, permease
MB46_06075	ENOG4105E0A	ABC, transporter
MB46_06085	ENOG4105C6F	GntR Family Transcriptional Regulator
MB46_06090	ENOG4105DEF	Extracellular solute-binding protein, family 5
MB46_06100	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
MB46_06105	ENOG4108JQ6	ABC transporter
MB46_06115	ENOG4105CHR	reductase
MB46_06120	ENOG4105C26	Dehydrogenase
MB46_06125	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
MB46_06130	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
MB46_06135	ENOG4105C26	Dehydrogenase
MB46_06150	ENOG4105CPC	Aldo Keto reductase
MB46_06175	ENOG4105F27	Major Facilitator
MB46_06195	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
MB46_06200	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
MB46_06205	ENOG4105ETE	Transcriptional regulator (LacI family
MB46_06215	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
MB46_06220	ENOG4105DRS	transport system, permease
MB46_06275	ENOG4105DCF	alanine dehydrogenase
MB46_06320	ENOG4108JQ6	ABC transporter
MB46_06325	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
MB46_06340	ENOG4105ETE	Transcriptional regulator (LacI family
MB46_06360	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
MB46_06395	ENOG4105CEY	Amp-dependent synthetase and ligase
MB46_06395	ENOG4105CEY	Amp-dependent synthetase and ligase
MB46_06420	ENOG4105CPC	Aldo Keto reductase
MB46_06425	ENOG4105E9Z	Nad-dependent epimerase dehydratase
MB46_06430	ENOG4107YB1	Trehalose corynomycolyl transferase
MB46_06460	ENOG4107RNA	Nickel ABC transporter, periplasmic nickel-binding protein
MB46_06475	ENOG4106N3A	copper homeostasis protein cutc
MB46_06485	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
MB46_06490	ENOG4105JSC	dimethylmenaquinone methyltransferase
MB46_06500	ENOG4105CSH	Transporter
MB46_06510	ENOG4105CSH	Transporter
MB46_06515	ENOG4105C7K	acetolactate synthase
MB46_06520	ENOG4105C26	Dehydrogenase
MB46_06525	ENOG4105EFZ	amidohydrolase
MB46_06530	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
MB46_06535	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
MB46_06545	ENOG4108HKT	sucrose-6-phosphate hydrolase
MB46_06550	ENOG4105E0S	extracellular solute-binding protein family 1
MB46_06555	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
MB46_06565	ENOG4105ETE	Transcriptional regulator (LacI family
MB46_06595	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
MB46_06610	ENOG4108ZJ4	polysaccharide deacetylase
MB46_06660	ENOG4105D29	Helix-turn-helix type 11 domain protein
MB46_06675	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
MB46_06770	ENOG4105E2A	Dehydrogenase
MB46_06780	ENOG4105DTD	Dehydrogenase
MB46_06810	ENOG4105MSY	salicylate hydroxylase
MB46_06815	ENOG4105D2S	major facilitator superfamily
MB46_06830	ENOG4105ERH	Fumarylacetoacetate hydrolase
MB46_06840	ENOG4105RHY	Pfam:UPF0157
MB46_06845	ENOG4105KVH	Transcriptional regulator
MB46_06850	ENOG4105ECR	NmrA family
MB46_06870	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
MB46_06895	ENOG4108UMI	ABC transporter, permease
MB46_06900	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
MB46_06905	ENOG4105D01	(LipO)protein
MB46_06935	ENOG4106NZI	LysR family Transcriptional regulator
MB46_06950	ENOG4105WH1	Two component transcriptional regulator luxr family
MB46_06960	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
MB46_07020	ENOG4106NZI	LysR family Transcriptional regulator
MB46_07025	ENOG4105CSH	Transporter
MB46_07050	ENOG4105C26	Dehydrogenase
MB46_07060	ENOG4108FUF	Transcriptional regulator, IclR family
MB46_07065	ENOG4105ERH	Fumarylacetoacetate hydrolase
MB46_07075	ENOG4105C26	Dehydrogenase
MB46_07100	ENOG4105QPS	Monooxygenase
MB46_07110	ENOG4105MSB	protein, conserved in bacteria
MB46_07120	ENOG4105D1H	recombination factor protein RarA
MB46_07135	ENOG4105BZU	Histidine kinase
MB46_07140	ENOG4105WH1	Two component transcriptional regulator luxr family
MB46_07190	ENOG4108SUT	Major Facilitator Superfamily
MB46_07290	ENOG41067RQ	csbd family
MB46_07340	ENOG4107QWE	)-transporter
MB46_07345	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
MB46_07350	ENOG4105CFC	Transporter
MB46_07460	ENOG4105FDP	GntR family transcriptional regulator
MB46_07505	ENOG4105EQ0	Major Facilitator superfamily
MB46_07510	ENOG4105F27	Major Facilitator
MB46_07515	ENOG4105WAB	arsR family transcriptional regulator
MB46_07525	ENOG410836F	Transposase
MB46_07530	ENOG4108KQ5	Integrase catalytic subunit
MB46_07535	ENOG4107QWE	)-transporter
MB46_07540	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
MB46_07545	ENOG4105CFC	Transporter
MB46_07560	ENOG4105CEU	Arginine dihydrolase
MB46_07565	ENOG4105D5Q	Arginine ornithine antiporter
MB46_07620	ENOG4105CBC	glutamate synthase
MB46_07630	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
MB46_07635	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
MB46_07640	ENOG4105DK0	Indole-3-glycerol phosphate synthase
MB46_07660	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
MB46_07670	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
MB46_07675	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
MB46_07680	ENOG4105M0N	phosphoribosyl-ATP pyrophosphatase
MB46_07685	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
MB46_07690	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
MB46_07695	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
MB46_07715	ENOG4105DJV	ribulose-phosphate 3-epimerase
MB46_07725	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
MB46_07730	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
MB46_07775	ENOG4105KPY	Small multidrug resistance protein
MB46_07785	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
MB46_07800	ENOG4108Z66	YbaK ebsC protein
MB46_07815	ENOG4105E0X	reductase
MB46_07840	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
MB46_07845	ENOG4105CHU	acetyl-coa acetyltransferase
MB46_07850	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
MB46_07860	ENOG4105CPC	Aldo Keto reductase
MB46_07875	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
MB46_07880	ENOG4107QM5	aconitate hydratase
MB46_07890	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
MB46_07895	ENOG4105C0X	amino acid
MB46_07900	ENOG4107VEG	TrkA-N domain protein
MB46_07925	ENOG4107ZFB	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
MB46_07980	ENOG4108JJ9	ABC, transporter
MB46_07985	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
MB46_07990	ENOG4105C4M	(Ubiquinol oxidase) subunit I
MB46_08020	ENOG4105WH1	Two component transcriptional regulator luxr family
MB46_08025	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
MB46_08045	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
MB46_08075	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
MB46_08080	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
MB46_08115	ENOG4105CSV	Glutaminase
MB46_08120	ENOG4105CDA	abc transporter atp-binding protein
MB46_08125	ENOG4105E5Q	amino acid AbC transporter
MB46_08135	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
MB46_08140	ENOG4105C5F	glutamine synthetase
MB46_08145	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
MB46_08165	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
MB46_08170	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
MB46_08175	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
MB46_08185	ENOG4105C0B	DNA polymerase III (alpha subunit)
MB46_08195	ENOG4107ZIW	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
MB46_08200	ENOG4107VQS	DivIVA family
MB46_08210	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
MB46_08215	ENOG4105DFA	alanine racemase domain protein
MB46_08220	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
MB46_08225	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
MB46_08230	ENOG4108Z36	domain protein, FtsQ-type
MB46_08235	ENOG4105DFU	Cell wall formation (By similarity)
MB46_08240	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
MB46_08250	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
MB46_08255	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
MB46_08265	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
MB46_08270	ENOG4105CJN	penicillin-binding protein
MB46_08280	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
MB46_08285	ENOG4108V6E	Cell division protein mraZ
MB46_08295	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
MB46_08315	ENOG41068JE	domain protein
MB46_08325	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
MB46_08345	ENOG4105DKQ	ROK family
MB46_08355	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
MB46_08360	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MB46_08385	ENOG4108UW8	fha domain-containing protein
MB46_08410	ENOG41083TI	Protein CrcB homolog
MB46_08415	ENOG4105CSU	acyl-Coa dehydrogenase
MB46_08440	ENOG4107RSZ	Primosomal protein n'
MB46_08445	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
MB46_08455	ENOG4105MTQ	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
MB46_08460	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
MB46_08465	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
MB46_08470	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
MB46_08475	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
MB46_08480	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
MB46_08490	ENOG4105CD3	dihydroorotase
MB46_08495	ENOG4105CXT	aspartate transcarbamylase
MB46_08500	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
MB46_08510	ENOG410803B	Involved in the transcription termination process (By similarity)
MB46_08515	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
MB46_08525	ENOG4105D49	3-dehydroquinate synthase
MB46_08530	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
MB46_08535	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
MB46_08540	ENOG4105E2X	shikimate dehydrogenase
MB46_08550	ENOG41080G3	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
MB46_08555	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
MB46_08570	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
MB46_08595	ENOG4105EHG	Permease protein
MB46_08605	ENOG4105E0A	ABC, transporter
MB46_08620	ENOG4105C9M	aspartyl-trna synthetase
MB46_08625	ENOG4105CUT	histidyl-tRNA synthetase
MB46_08635	ENOG4105C99	atpase involved in dna repair
MB46_08645	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
MB46_08650	ENOG4107RTU	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
MB46_08655	ENOG4107RSV	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
MB46_08665	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
MB46_08670	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
MB46_08675	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
MB46_08680	ENOG4105CDY	transcriptional regulatory protein
MB46_08685	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
MB46_08690	ENOG4105CAQ	asparagine synthetase
MB46_08695	ENOG4105DGW	oligopeptidase A
MB46_08700	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
MB46_08705	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
MB46_08710	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
MB46_08715	ENOG4108VTU	Cdp-alcohol phosphatidyltransferase
MB46_08725	ENOG4105C22	threonyL-tRNA synthetase
MB46_08730	ENOG4105C0B	DNA polymerase III (alpha subunit)
MB46_08740	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
MB46_08750	ENOG4108RAV	Conserved protein
MB46_08785	ENOG4105CEY	Amp-dependent synthetase and ligase
MB46_08795	ENOG4108Z12	YiaAB two helix domain-containing protein
MB46_08800	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
MB46_08805	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
MB46_08810	ENOG4105G3E	Probably involved in ribonucleotide reductase function (By similarity)
MB46_08825	ENOG4108RFG	Tetr family transcriptional regulator
MB46_08830	ENOG4108UW5	maltose o-acetyltransferase
MB46_08835	ENOG4105CWB	LysR family transcriptional Regulator
MB46_08840	ENOG4105C26	Dehydrogenase
MB46_08850	ENOG4105SYT	Methylenetetrahydrofolate reductase
MB46_08880	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
MB46_08895	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
MB46_08900	ENOG4105K5B	UPF0225 protein
MB46_08905	ENOG4105FDP	GntR family transcriptional regulator
MB46_08925	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
MB46_08935	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
MB46_08945	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
MB46_08950	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
MB46_08955	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MB46_08960	ENOG4105K46	50S ribosomal protein l27
MB46_08965	ENOG410826X	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
MB46_08970	ENOG4105DWF	phosphomethylpyrimidine kinase
MB46_08975	ENOG4105C03	ribonuclease
MB46_08985	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
MB46_08995	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
MB46_09000	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
MB46_09010	ENOG4105K78	MarR family Transcriptional regulator
MB46_09020	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
MB46_09030	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
MB46_09035	ENOG4105BZF	Glycosyl transferase (Group 1
MB46_09040	ENOG4105MC2	DSBA oxidoreductase
MB46_09045	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
MB46_09050	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
MB46_09055	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
MB46_09060	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
MB46_09070	ENOG4108KQ5	Integrase catalytic subunit
MB46_09085	ENOG4108YZG	isomerase
MB46_09115	ENOG4108Z18	K06886 hemoglobin
MB46_09130	ENOG4105C29	acyl-CoA thioesterase
MB46_09185	ENOG4105E5G	Alpha beta hydrolase fold
MB46_09200	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
MB46_09210	ENOG4105DGI	Alkaline phosphatase
MB46_09220	ENOG4105ECQ	AraC Family Transcriptional Regulator
MB46_09240	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
MB46_09245	ENOG4107WHG	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
MB46_09255	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
MB46_09260	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
MB46_09265	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
MB46_09300	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
MB46_09310	ENOG41090CE	integral membrane protein
MB46_09330	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
MB46_09355	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
MB46_09370	ENOG4107XFJ	UPF0246 protein
MB46_09380	ENOG4105EGD	dinuclear metal center protein, YbgI family
MB46_09385	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
MB46_09395	ENOG4105D7W	serine acetyltransferase
MB46_09400	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
MB46_09405	ENOG4105CPQ	Dehydrogenase
MB46_09410	ENOG4105CHR	reductase
MB46_09415	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
MB46_09440	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
MB46_09465	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
MB46_09480	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
MB46_09485	ENOG41082KT	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
MB46_09490	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
MB46_09500	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
MB46_09510	ENOG4105C0P	Mg chelatase subunit ChlI
MB46_09515	ENOG41080R2	UPF0102 protein
MB46_09525	ENOG4105C26	Dehydrogenase
MB46_09530	ENOG4105C94	Transporter
MB46_09535	ENOG4108RYK	Nad-dependent epimerase dehydratase
MB46_09540	ENOG4105KVH	Transcriptional regulator
MB46_09550	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
MB46_09555	ENOG4107QYR	Signal peptidase i
MB46_09560	ENOG4107QYR	Signal peptidase i
MB46_09565	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
MB46_09570	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
MB46_09575	ENOG4107XUM	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
MB46_09580	ENOG41082KU	UPF0109 protein
MB46_09585	ENOG4105K5M	30s ribosomal protein S16
MB46_09595	ENOG4108TKW	Glyoxalase Bleomycin resistance protein (Dioxygenase
MB46_09600	ENOG4105XYF	acetyltransferase
MB46_09620	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
MB46_09645	ENOG410838F	Glycosyl transferase family 2
MB46_09665	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MB46_09670	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
MB46_09675	ENOG4105MXW	flavin reductase domain protein, FMN-binding
MB46_09685	ENOG4105EAB	amino acid AbC transporter
MB46_09695	ENOG4105CPU	Monooxygenase
MB46_09715	ENOG4105E5Q	amino acid AbC transporter
MB46_09735	ENOG4105E2T	synthase III
MB46_09740	ENOG410680H	amp-dependent synthetase and ligase
MB46_09745	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
MB46_09755	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
MB46_09760	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
MB46_09765	ENOG41062IY	50S ribosomal protein L32
MB46_09775	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
MB46_09790	ENOG4107TYG	Oxidoreductase domain-containing protein
MB46_09800	ENOG4105DZ6	Band 7 protein
MB46_09810	ENOG4106H78	methyltransferase
MB46_09845	ENOG4105CHR	reductase
MB46_09850	ENOG4105CGP	Urocanate hydratase
MB46_09855	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
MB46_09870	ENOG4105E0A	ABC, transporter
MB46_09875	ENOG4105J76	Periplasmic binding protein
MB46_09880	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
MB46_09885	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
MB46_09900	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
MB46_09915	ENOG4105CPF	Cell wall formation (By similarity)
MB46_09920	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
MB46_09930	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
MB46_09935	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
MB46_09940	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
MB46_09945	ENOG41069M3	Transcriptional regulator
MB46_09975	ENOG4107XGZ	Hydrolase
MB46_09980	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
MB46_10000	ENOG4105C85	amino acid
MB46_10005	ENOG4105WH1	Two component transcriptional regulator luxr family
MB46_10010	ENOG4105BZU	Histidine kinase
MB46_10030	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
MB46_10040	ENOG4105CM2	brancheD-chain amino acid aminotransferase
MB46_10055	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
MB46_10060	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
MB46_10080	ENOG4105EWK	phytoene
MB46_10100	ENOG4105CGD	Nad-dependent epimerase dehydratase
MB46_10105	ENOG4105BZU	Histidine kinase
MB46_10110	ENOG4105WH1	Two component transcriptional regulator luxr family
MB46_10120	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
MB46_10125	ENOG4105XN3	extracellular solute-binding protein family 1
MB46_10135	ENOG41073TP	transcriptional regulator
MB46_10145	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
MB46_10150	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
MB46_10175	ENOG4106N3A	copper homeostasis protein cutc
MB46_10190	ENOG4105EZX	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity)
MB46_10195	ENOG4105EX2	Binding-protein-dependent transport systems, inner membrane component
MB46_10215	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
MB46_10220	ENOG4108ZP8	Acetolactate synthase small subunit
MB46_10230	ENOG4105C01	Dihydroxy-acid dehydratase
MB46_10245	ENOG4105VTR	Integrase
MB46_10300	ENOG4105FA0	parb-like partition protein
MB46_10470	ENOG4105E2D	ec 3.2.1.52
MB46_10485	ENOG4105DEF	Extracellular solute-binding protein, family 5
MB46_10490	ENOG4105DWT	malate dehydrogenase (quinone)
MB46_10500	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
MB46_10505	ENOG41079Y2	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone
MB46_10510	ENOG4105K56	Transcriptional regulator
MB46_10530	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
MB46_10545	ENOG4105D5T	phosphonate abc transporter
MB46_10555	ENOG4105S7S	phosphonate abc transporter
MB46_10560	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
MB46_10570	ENOG4105ERH	Fumarylacetoacetate hydrolase
MB46_10585	ENOG4107QI6	Cysteine desulfurase
MB46_10590	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
MB46_10600	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
MB46_10620	ENOG4105DQ5	transport system permease protein
MB46_10625	ENOG4105TVJ	transport system, permease
MB46_10630	ENOG4105E0A	ABC, transporter
MB46_10635	ENOG4105C85	amino acid
MB46_10640	ENOG4108MXF	Alpha Beta Hydrolase
MB46_10650	ENOG4105EYH	Exonuclease
MB46_10655	ENOG4107RH8	nuclease SbcCD subunit D
MB46_10660	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
MB46_10670	ENOG4105VG5	Membrane
MB46_10700	ENOG4105DVE	abc transporter atp-binding protein
MB46_10715	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
MB46_10720	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
MB46_10730	ENOG4108RQ5	Beta-lactamase domain-containing protein
MB46_10735	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
MB46_10745	ENOG4105KEN	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
MB46_10750	ENOG4107RKP	Nicotinate phosphoribosyltransferase
MB46_10755	ENOG4108RWI	nicotinamidase
MB46_10770	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
MB46_10785	ENOG41080RH	Thioredoxin
MB46_10805	ENOG4105CYV	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures (By similarity)
MB46_10810	ENOG4105CE4	GlcNAc 6-P deacetylase
MB46_10820	ENOG4105FF5	Membrane
MB46_10825	ENOG4108SEA	Esterase
MB46_10835	ENOG410825K	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
MB46_10840	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
MB46_10845	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
MB46_10850	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
MB46_10855	ENOG4108T62	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
MB46_10860	ENOG4107Z0K	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
MB46_10865	ENOG4106DE0	ATP synthase
MB46_10870	ENOG4107UH5	it plays a direct role in the translocation of protons across the membrane (By similarity)
MB46_10885	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
MB46_10900	ENOG4108MKI	Glycosyl transferase, family 2
MB46_10920	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
MB46_10925	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
MB46_10935	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
MB46_10940	ENOG4107R5I	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
MB46_10945	ENOG4105D6E	homoserine dehydrogenase
MB46_10950	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
MB46_10955	ENOG4105C75	arginyL-tRNA synthetase
MB46_10990	ENOG410849A	acetyltransferase, (GNAT) family
MB46_11000	ENOG4108ZT1	Transcriptional regulator
MB46_11010	ENOG4105CQ7	ATP-dependent helicase
MB46_11020	ENOG4105CHR	reductase
MB46_11030	ENOG4107ZUX	Histidine triad (HIT) protein
MB46_11035	ENOG4105DQ4	alcohol dehydrogenase
MB46_11045	ENOG4105C6T	cysteine synthase
MB46_11095	ENOG4105C37	(CBS) domain
MB46_11105	ENOG4108Z4X	TRANSCRIPTIONal
MB46_11110	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
MB46_11115	ENOG4105D17	glycoside hydrolase, family 3 domain protein
MB46_11120	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
MB46_11125	ENOG4105CXK	mandelate racemase muconate lactonizing
MB46_11130	ENOG4105CT4	transporter
MB46_11135	ENOG4105DEI	Mannitol dehydrogenase
MB46_11140	ENOG4105D2H	Uronic isomerase
MB46_11145	ENOG4105ETE	Transcriptional regulator (LacI family
MB46_11190	ENOG4105ETE	Transcriptional regulator (LacI family
MB46_11200	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
MB46_11230	ENOG4105EMN	RNA polymerase sigma factor
MB46_11240	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
MB46_11250	ENOG4107TK4	histidinol-phosphate phosphatase
MB46_11255	ENOG4105C9B	Cysteine desulfurase
MB46_11260	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
MB46_11270	ENOG4107R5H	iron (metal) dependent repressor, dtxr family
MB46_11310	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
MB46_11315	ENOG4105DR5	peptidase
MB46_11335	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
MB46_11375	ENOG4105EXC	Acyl-transferase
MB46_11390	ENOG4105CMR	udp-glucose 4-epimerase
MB46_11400	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
MB46_11425	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
MB46_11455	ENOG4107QPT	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
MB46_11475	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
MB46_11510	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
MB46_11530	ENOG4107QQG	Dehydrogenase
MB46_11535	ENOG4105EXC	Acyl-transferase
MB46_11540	ENOG4105EY8	ABC transporter
MB46_11550	ENOG410602S	Transferase
MB46_11560	ENOG4105EC2	ftsk spoIIIe
MB46_11570	ENOG4105KRM	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
MB46_11580	ENOG4105C7I	Dehydrogenase
MB46_11615	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
MB46_11620	ENOG4105T0Z	Conserved Protein
MB46_11625	ENOG4108S7Q	sigma 54 modulation protein ribosomal protein S30ea
MB46_11630	ENOG4105MJ2	Competence protein
MB46_11635	ENOG4108T3R	lipoprotein lpqB
MB46_11640	ENOG4105BZU	Histidine kinase
MB46_11645	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
MB46_11660	ENOG4108WQ6	secreted protein
MB46_11665	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
MB46_11690	ENOG4108JQ6	ABC transporter
MB46_11695	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
MB46_11700	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
MB46_11705	ENOG4105DEF	Extracellular solute-binding protein, family 5
MB46_11715	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
MB46_11725	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
MB46_11735	ENOG4105EUJ	GTP cyclohydrolase i
MB46_11745	ENOG4105EEI	dihydropteroate synthase
MB46_11770	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
MB46_11775	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
MB46_11780	ENOG4105C10	Electron transfer flavoprotein
MB46_11800	ENOG4105C0H	protease
MB46_11810	ENOG41087YS	Phage shock protein A
MB46_11815	ENOG4105CV8	reductase
MB46_11825	ENOG4105CPC	Aldo Keto reductase
MB46_11835	ENOG4105F4R	Transcriptional regulator mode
MB46_11875	ENOG4108IPT	Naphthoate synthase
MB46_11880	ENOG4105C1G	acyl-Coa dehydrogenase
MB46_11890	ENOG41067TZ	transcriptional regulator, MarR family
MB46_11895	ENOG4105E39	Enoyl-CoA hydratase
MB46_11900	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
MB46_11905	ENOG4105CHU	acetyl-coa acetyltransferase
MB46_11910	ENOG4105DSF	transport protein
MB46_11915	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
MB46_11920	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
MB46_11935	ENOG4107QWE	)-transporter
MB46_11945	ENOG4105DJZ	UPF0182 protein
MB46_11950	ENOG41063PX	domain protein
MB46_11985	ENOG4105C4R	Atp-dependent dna helicase
MB46_12005	ENOG4105EAB	amino acid AbC transporter
MB46_12010	ENOG4105EAD	ABC transporter
MB46_12015	ENOG4105CDA	abc transporter atp-binding protein
MB46_12020	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
MB46_12035	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
MB46_12040	ENOG4107QME	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
MB46_12045	ENOG4107JTW	chlorite dismutase
MB46_12055	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
MB46_12060	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
MB46_12075	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
MB46_12080	ENOG4108UMI	ABC transporter, permease
MB46_12085	ENOG4105D01	(LipO)protein
MB46_12110	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
MB46_12120	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
MB46_12125	ENOG4107Y5I	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
MB46_12135	ENOG4105CK7	Sodium proline symporter
MB46_12155	ENOG4108T3F	Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes
MB46_12170	ENOG4105DEN	Luciferase family
MB46_12180	ENOG4105H3G	oxidoreductase
MB46_12215	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
MB46_12230	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
MB46_12235	ENOG4105DAE	Methylenetetrahydrofolate reductase
MB46_12240	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
MB46_12250	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
MB46_12255	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
MB46_12260	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
MB46_12265	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MB46_12280	ENOG4106NZI	LysR family Transcriptional regulator
MB46_12285	ENOG4105D94	Major Facilitator Superfamily
MB46_12290	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
MB46_12310	ENOG4105E5Q	amino acid AbC transporter
MB46_12315	ENOG4105CDA	abc transporter atp-binding protein
MB46_12340	ENOG4105C1J	atp-dependent rna helicase
MB46_12355	ENOG4107T6F	Xaa-Pro aminopeptidase
MB46_12375	ENOG4105CJW	magnesium transporter
MB46_12390	ENOG410630M	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
MB46_12415	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
MB46_12425	ENOG4108URH	decarboxylase
MB46_12430	ENOG4105CDA	abc transporter atp-binding protein
MB46_12435	ENOG4107UBR	Extracellular solute-binding protein family 3
MB46_12440	ENOG4108Q1T	ABC transporter
MB46_12445	ENOG4105DRP	amino acid AbC transporter
MB46_12450	ENOG4107R4C	succinyl-diaminopimelate desuccinylase
MB46_12460	ENOG4105K6V	RNA polymerase
MB46_12465	ENOG4105RNG	membrane
MB46_12475	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
MB46_12490	ENOG4105W1N	transcriptional regulator
MB46_12510	ENOG4108Z4U	Ferredoxin
MB46_12525	ENOG4108KZ5	Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway (By similarity)
MB46_12530	ENOG4108JQ6	ABC transporter
MB46_12535	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
MB46_12540	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
MB46_12550	ENOG4105CI3	gtp-binding protein typa
MB46_12555	ENOG4108NY6	Extracellular solute-binding protein, family 5
MB46_12575	ENOG4105CKW	Inner membrane protein yedI
MB46_12610	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
MB46_12645	ENOG4105C3G	gtp-binding protein
MB46_12650	ENOG4105CGY	Dna recombination protein
MB46_12655	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
MB46_12665	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
MB46_12670	ENOG4105YX8	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
MB46_12680	ENOG4105CSR	polyphosphate kinase 2
MB46_12700	ENOG4105ETE	Transcriptional regulator (LacI family
MB46_12705	ENOG4105RD7	BadF BadG BcrA BcrD
MB46_12710	ENOG4105EA8	2-Nitropropane dioxygenase
MB46_12715	ENOG4105EW9	transcriptional regulator AsnC family
MB46_12720	ENOG4105D7N	magnesium and cobalt transport protein CorA
MB46_12730	ENOG4108RDT	NADH dehydrogenase NAD(P)H nitroreductase)
MB46_12740	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
MB46_12755	ENOG4108X07	Tetr family transcriptional regulator
MB46_12760	ENOG4105CIG	ABC transporter
MB46_12775	ENOG41086KC	Transcriptional regulator
MB46_12805	ENOG4105C5H	ABC transporter
MB46_12815	ENOG4105CAC	Catalyzes the conversion of L-arabinose to L-ribulose (By similarity)
MB46_12825	ENOG4105EF1	ribulokinase
MB46_12830	ENOG4105ETE	Transcriptional regulator (LacI family
MB46_12835	ENOG4107WI4	Aldose-1-epimerase
MB46_12850	ENOG4106NZI	LysR family Transcriptional regulator
MB46_12855	ENOG4105D53	Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity)
MB46_12860	ENOG4108MGF	sugar kinase
MB46_12875	ENOG4105C5Y	PTS System
MB46_12890	ENOG4105DQ4	alcohol dehydrogenase
MB46_12905	ENOG4105NTW	Transcriptional regulator
MB46_12935	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
MB46_12940	ENOG41080UU	5-formyltetrahydrofolate cyclo-ligase
MB46_12965	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
MB46_12985	ENOG4107QVP	Dehydrogenase
MB46_13020	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
MB46_13025	ENOG4105EXC	Acyl-transferase
MB46_13035	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
MB46_13040	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
MB46_13060	ENOG4108IPW	abc transporter atp-binding protein
MB46_13065	ENOG4105CM4	permease protein
MB46_13085	ENOG4105F9E	Shikimate 5-dehydrogenase
MB46_13090	ENOG4106KXD	ATP-dependent carboxylate-amine ligase (By similarity)
MB46_13095	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
MB46_13125	ENOG4105DRS	transport system, permease
MB46_13135	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
MB46_13140	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
MB46_13150	ENOG4108097	ATP-binding protein
MB46_13155	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
MB46_13160	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
MB46_13175	ENOG4105E2R	ROK family
MB46_13215	ENOG4105CPC	Aldo Keto reductase
MB46_13230	ENOG41082KK	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
MB46_13235	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
MB46_13240	ENOG4105CS9	pantothenic acid kinase
MB46_13250	ENOG41080FJ	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
MB46_13255	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
MB46_13260	ENOG4108UJD	30S ribosomal protein S9
MB46_13265	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
MB46_13270	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
MB46_13275	ENOG4108ZT0	50S ribosomal protein l17
MB46_13280	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
MB46_13285	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
MB46_13290	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MB46_13300	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
MB46_13305	ENOG4105KXX	peptidase s58 dmpa
MB46_13310	ENOG4105BZ7	extracellular solute-binding protein family 1
MB46_13320	ENOG4105EQ7	Binding-protein-dependent transport systems, inner membrane component
MB46_13330	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
MB46_13335	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
MB46_13350	ENOG410849U	50S ribosomal protein L30
MB46_13355	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
MB46_13360	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
MB46_13365	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
MB46_13370	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
MB46_13375	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MB46_13380	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
MB46_13385	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
MB46_13390	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
MB46_13395	ENOG41082SA	50s ribosomal protein l29
MB46_13400	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
MB46_13405	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
MB46_13410	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
MB46_13415	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
MB46_13420	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MB46_13425	ENOG4105KZR	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
MB46_13430	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
MB46_13435	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
MB46_13440	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
MB46_13455	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
MB46_13460	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
MB46_13465	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
MB46_13470	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
MB46_13475	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
MB46_13480	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
MB46_13485	ENOG4105CHU	acetyl-coa acetyltransferase
MB46_13495	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
MB46_13500	ENOG4108VZM	50s ribosomal protein L10
MB46_13515	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
MB46_13520	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
MB46_13525	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
MB46_13530	ENOG410683Z	Preprotein translocase SecE subunit
MB46_13545	ENOG4105WH1	Two component transcriptional regulator luxr family
MB46_13585	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
MB46_13590	ENOG4108X6U	May play a role in the intracellular transport of hydrophobic ligands
MB46_13600	ENOG4107NHD	transcriptional regulator
MB46_13615	ENOG4105C5I	Dehydrogenase
MB46_13630	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
MB46_13635	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
MB46_13645	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
MB46_13650	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
MB46_13675	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
MB46_13700	ENOG4107QJH	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
MB46_13720	ENOG4107R4N	Cell wall formation (By similarity)
MB46_13725	ENOG4106UW1	Major Facilitator superfamily
MB46_13735	ENOG410900P	UPF0336 protein
MB46_13745	ENOG4105C57	major facilitator superfamily
MB46_13760	ENOG4105CI0	Citrate lyase
MB46_13780	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
MB46_13790	ENOG4105CPU	Monooxygenase
MB46_13795	ENOG4105EEQ	Na H antiporter
MB46_13850	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
MB46_13860	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
MB46_13865	ENOG4105DTD	Dehydrogenase
MB46_13870	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
MB46_13875	ENOG4105MS9	Resuscitation-promoting factor
MB46_13920	ENOG4105C26	Dehydrogenase
MB46_13925	ENOG4105DZ2	Transcriptional regulator
MB46_13935	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
MB46_13945	ENOG4105D7T	ABC transporter
MB46_13960	ENOG4108HMR	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
MB46_13965	ENOG4107RHR	regulatoR
MB46_13970	ENOG4105CPQ	Dehydrogenase
MB46_13975	ENOG4105IE8	Alpha-ketoglutarate permease
MB46_13980	ENOG4105CMT	Dihydroxyacetone kinase
MB46_13985	ENOG4107YVI	ribose 5-phosphate isomerase
MB46_13990	ENOG4105CHR	reductase
MB46_14000	ENOG41080RH	Thioredoxin
MB46_14025	ENOG4108VPT	UPF0234 protein
MB46_14040	ENOG4105BZU	Histidine kinase
MB46_14045	ENOG4105GCF	PGAM
MB46_14050	ENOG4108Z7F	N-acetyltransferase
MB46_14060	ENOG4105D0M	Protease HtpX homolog
MB46_14080	ENOG4105CH6	catalase
MB46_14100	ENOG4105CUB	amino acid
MB46_14125	ENOG4107QN2	dihydrolipoyl dehydrogenase
MB46_14150	ENOG4105C26	Dehydrogenase
MB46_14185	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
MB46_14190	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
MB46_14250	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
MB46_14255	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
MB46_14275	ENOG4108IUX	(ABC) transporter
MB46_14280	ENOG4105EN6	Membrane
MB46_14305	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
MB46_14310	ENOG4105E4F	Isochorismate synthase
MB46_14315	ENOG4108HW3	(ABC) transporter
MB46_14320	ENOG4105E5Q	amino acid AbC transporter
MB46_14325	ENOG4105CDA	abc transporter atp-binding protein
MB46_14335	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
MB46_14340	ENOG4107TCW	O-succinylbenzoate synthase
MB46_14360	ENOG4107RN0	branched-chain alpha-keto acid dehydrogenase subunit E2
MB46_14375	ENOG4105EW9	transcriptional regulator AsnC family
MB46_14390	ENOG4107TE5	Lipid kinase
MB46_14405	ENOG4105CQB	FAD linked oxidase domain protein
MB46_14410	ENOG4105CHR	reductase
MB46_14420	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
MB46_14425	ENOG4108ZA2	phenylacetate-CoA oxygenase PaaJ subunit
MB46_14430	ENOG4105D9S	phenylacetate-CoA oxygenase PaaI subunit
MB46_14435	ENOG4105N76	Phenylacetate-CoA oxygenase, subunit
MB46_14440	ENOG4105CRS	phenylacetate-CoA oxygenase PaaG subunit
MB46_14445	ENOG4108ZJI	phenylacetic acid degradation protein
MB46_14460	ENOG4105DXM	phenylacetic acid degradation protein
MB46_14465	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
MB46_14470	ENOG4105E39	Enoyl-CoA hydratase
MB46_14475	ENOG4105CHU	acetyl-coa acetyltransferase
MB46_14535	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
MB46_14540	ENOG4105ETE	Transcriptional regulator (LacI family
MB46_14550	ENOG4105CJQ	hydrolase, family 31
MB46_14565	ENOG4105M2Z	protein tyrosine serine phosphatase
MB46_14585	ENOG4107SIQ	Naphthoate synthase
MB46_14645	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
MB46_14665	ENOG4108V06	Glutathione peroxidase
MB46_14685	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
MB46_14695	ENOG4105C01	Dihydroxy-acid dehydratase
MB46_14705	ENOG4105CJ1	ABC, transporter
MB46_14710	ENOG4105CFH	Aspartokinase
MB46_14755	ENOG4105C2W	permease
MB46_14760	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
MB46_14765	ENOG410633P	Hydantoin racemase
MB46_14770	ENOG4105EW8	cytosine purines, uracil, thiamine, allantoin permease
MB46_14775	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
MB46_14800	ENOG41069M3	Transcriptional regulator
MB46_14810	ENOG4107R9S	Malate synthase
MB46_14820	ENOG4105S0E	allantoin catabolism protein
MB46_14830	ENOG4107TFQ	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
MB46_14835	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
MB46_14840	ENOG41060W2	glyoxylate carboligase
MB46_14845	ENOG4105BZW	Glycerate kinase
MB46_14875	ENOG410839H	phosphoribosylformylglycinamidine synthase
MB46_14880	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
MB46_14885	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
MB46_14910	ENOG4105K4P	CoA-binding domain protein
MB46_14920	ENOG4107QPI	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
MB46_14925	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
MB46_14940	ENOG4107RCW	fructose-bisphosphate aldolase
MB46_14945	ENOG4108JEZ	rRNA small subunit methyltransferase G
MB46_14960	ENOG4107104	thymidine kinase
MB46_14965	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
MB46_14970	ENOG4105CXK	mandelate racemase muconate lactonizing
MB46_14980	ENOG4108RTU	Aldolase
MB46_14985	ENOG4105CXK	mandelate racemase muconate lactonizing
MB46_14990	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
MB46_15025	ENOG4108IJ7	Glycine betaine
MB46_15040	ENOG4105ETE	Transcriptional regulator (LacI family
MB46_15065	ENOG4105CG3	alpha amylase, catalytic region
MB46_15095	ENOG4105VBF	alkaline shock protein
MB46_15145	ENOG4105JDN	Copper resistance protein
MB46_15150	ENOG4105C7N	Xanthine uracil vitamin C permease
MB46_15155	ENOG41088SP	formiminoglutamate hydrolase
MB46_15170	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
MB46_15180	ENOG4105C84	Histidine ammonia-lyase
MB46_15190	ENOG4105C85	amino acid
MB46_15225	ENOG4105BZP	glycoside hydrolase 15-related
MB46_15230	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
MB46_15235	ENOG4106BRA	Membrane
MB46_15255	ENOG4105E98	transcriptional regulator DeoR family
MB46_15260	ENOG4105DE4	1-phosphofructokinase
MB46_15265	ENOG4105DM4	PTS System
MB46_15270	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
MB46_15275	ENOG410849S	phosphocarrier protein (HPr)
MB46_15280	ENOG4105CSH	Transporter
MB46_15285	ENOG4105EMU	Dehydrogenase
MB46_15295	ENOG4105DWF	phosphomethylpyrimidine kinase
MB46_15320	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
MB46_15335	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
MB46_15365	ENOG4105E59	Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions (By similarity)
MB46_15380	ENOG4105VDH	Dihydroxyacetone kinase
MB46_15390	ENOG4105CMT	Dihydroxyacetone kinase
MB46_15410	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
MB46_15420	ENOG4105CRK	lysyL-tRNA synthetase
MB46_15425	ENOG4105ETE	Transcriptional regulator (LacI family
MB46_15430	ENOG4105DU0	nucleoside hydrolase
MB46_15435	ENOG4105C2C	drug resistance transporter, Bcr CflA
MB46_15440	ENOG4108RVA	ribokinase
MB46_15445	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
MB46_15470	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MB46_15485	ENOG4105EUJ	GTP cyclohydrolase i
MB46_15500	ENOG4107RD1	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
MB46_15510	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
MB46_15515	ENOG4105BZU	Histidine kinase
MB46_15550	ENOG4107RVU	D-Ala-D-Ala carboxypeptidase 3 (S13) family
MB46_15570	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
MB46_15575	ENOG4107TE5	Lipid kinase
MB46_15595	ENOG4105C72	UPF0176 protein
MB46_15600	ENOG4105DUX	Transporter
MB46_15625	ENOG4105C2W	permease
MB46_15630	ENOG4105BZW	Glycerate kinase
MB46_15640	ENOG4108K4B	hydrolase
MB46_15645	ENOG4105D7K	pfkb domain protein
MB46_15650	ENOG4105ETE	Transcriptional regulator (LacI family
MB46_15660	ENOG4105C09	Bile acid
MB46_15695	ENOG4105D5Q	Arginine ornithine antiporter
MB46_15735	ENOG41080R8	Conserved Protein
MB46_15740	ENOG4107QR9	Iron-sulfur cluster binding protein
MB46_15745	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
MB46_15790	ENOG4105CDW	Resistance protein
MB46_15820	ENOG4105DAX	Pfam:DUF2983
MB46_15855	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
MB46_15880	ENOG4105DFM	M18 family aminopeptidase
MB46_15885	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
MB46_15890	ENOG4105WH1	Two component transcriptional regulator luxr family
MB46_15895	ENOG4105BZU	Histidine kinase
MB46_15910	ENOG4108WIQ	phosphoesterase PA-phosphatase related protein
MB46_15915	ENOG4106UW1	Major Facilitator superfamily
MB46_15920	ENOG4108KAZ	Involved in phosphonate degradation (By similarity)
MB46_15925	ENOG4105FDP	GntR family transcriptional regulator
MB46_15940	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
MB46_15955	ENOG4105C5H	ABC transporter
MB46_15965	ENOG4105WH1	Two component transcriptional regulator luxr family
MB46_15980	ENOG4108VB1	regulatoR
MB46_15985	ENOG4105BZU	Histidine kinase
MB46_15995	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
MB46_16015	ENOG4107TB6	phosphoglycerate mutase
MB46_16020	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MB46_16040	ENOG4105C3M	thioredoxin reductase
MB46_16045	ENOG4105K63	Thioredoxin
MB46_16075	ENOG4107QJE	Chromosome Partitioning Protein
MB46_16080	ENOG4107XUG	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
MB46_16090	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MB46_16095	ENOG41084CH	50S ribosomal protein l34
MB46_16100	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
MB46_16105	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
MB46_16110	ENOG4108J5G	6-phosphogluconate dehydrogenase
MB46_16115	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
MB46_16120	ENOG4105K7N	UPF0232 protein
MB46_16125	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
MB46_16130	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
MB46_16135	ENOG4108ZED	Transmembrane domain of unknown function (DUF3566)
MB46_16170	ENOG4105MXW	flavin reductase domain protein, FMN-binding
MB46_16190	ENOG4105ZJT	Cell division protein CrgA
MB46_16195	ENOG4108U4N	(sortase) family
MB46_16210	ENOG4107TPY	serine threonine protein kinase
MB46_16215	ENOG4105CJN	penicillin-binding protein
MB46_16230	ENOG4105HZM	Fha domain containing protein
MB46_16235	ENOG4105TV9	FHA Domain-Containing protein
MB46_16295	ENOG410829C	Binds together with S18 to 16S ribosomal RNA (By similarity)
MB46_16305	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
MB46_16310	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
MB46_16320	ENOG4105CDU	Replicative dna helicase
MB46_16355	ENOG4108PSC	Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc). Binds to two adjacent inverted repeats within the operator region. MurNAc 6-phosphate, the substrate of MurQ, is the specific inducer that weakens binding of MurR to the operator (By similarity)
MB46_16360	ENOG4108SU4	UPF0309 protein
MB46_16400	ENOG4105VPX	protein, conserved in bacteria
MB46_16420	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
MB46_16430	ENOG4105CTS	PTS system mannitol-specific
MB46_16435	ENOG4107SQ3	mannitol-1-phosphate 5-dehydrogenase
MB46_16440	ENOG4105CPQ	Dehydrogenase
MB46_16460	ENOG4105DKT	Transcriptional regulator
MB46_16470	ENOG4105DEI	Mannitol dehydrogenase
MB46_16475	ENOG4105C7K	acetolactate synthase
MB46_16490	ENOG4105G3Z	GntR family transcriptional regulator
MB46_16505	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
MB46_16530	ENOG4105NAU	thioesterase Superfamily protein
MB46_16540	ENOG4107QTF	adenylosuccinate lyase
MB46_16555	ENOG41082T9	Membrane
MB46_16560	ENOG4105CIH	Imidazole acetol-phosphate transaminase
MB46_16570	ENOG4105CPP	Dehydrogenase, E1 component
MB46_16575	ENOG4107RN0	branched-chain alpha-keto acid dehydrogenase subunit E2
MB46_16580	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
MB46_16610	ENOG4105D9R	oxidoreductase
MB46_16655	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
MB46_16685	ENOG4107QN2	dihydrolipoyl dehydrogenase
MB46_16705	ENOG4108IJ8	ABC transporter
MB46_16710	ENOG4105CHF	Glutathione S-transferase
MB46_16730	ENOG4105DQ5	transport system permease protein
MB46_16735	ENOG4105TVJ	transport system, permease
MB46_16750	ENOG4108SQ4	Glyoxalase Bleomycin resistance protein (Dioxygenase
MB46_16760	ENOG4105BZ1	(ABC) transporter
MB46_16770	ENOG4105DJB	Major Facilitator Superfamily
MB46_16775	ENOG410846T	CoA-transferase family III
MB46_16780	ENOG4105C1G	acyl-Coa dehydrogenase
MB46_16790	ENOG4105CHU	acetyl-coa acetyltransferase
MB46_16795	ENOG4105BZJ	Electron transfer flavoprotein
MB46_16800	ENOG4105C10	Electron transfer flavoprotein
MB46_16830	ENOG4105KDC	50s ribosomal protein l28
MB46_16835	ENOG4105W0E	50S ribosomal protein L33
MB46_16840	ENOG41080FR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
MB46_16845	ENOG4108426	dNA-binding protein
MB46_16865	ENOG4105D7A	ATP-binding protein
MB46_16875	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
MB46_16880	ENOG4106NZI	LysR family Transcriptional regulator
MB46_16885	ENOG4105E8G	Major facilitator Superfamily
MB46_16900	ENOG4108KQ5	Integrase catalytic subunit
MB46_16915	ENOG4107RWR	Sodium hydrogen exchanger
MB46_16920	ENOG4107ZYR	domain protein
MB46_16925	ENOG4105DHP	deoxycytidine triphosphate deaminase
MB46_16935	ENOG4105D65	subunit l
MB46_16945	ENOG4108JPZ	Monovalent cation H antiporter subunit D
MB46_16955	ENOG41080TA	Multiple resistance and ph regulation protein f
MB46_16960	ENOG4105KJM	monovalent cation h antiporter subunit g
MB46_16970	ENOG4105NSK	ABC superfamily ATP binding cassette transporter membrane protein
MB46_16975	ENOG4108JJB	ABC transporter
MB46_16990	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
MB46_16995	ENOG4105DRS	transport system, permease
MB46_17000	ENOG4108HKT	sucrose-6-phosphate hydrolase
MB46_17005	ENOG4105ETE	Transcriptional regulator (LacI family
MB46_17010	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
MB46_17055	ENOG4105KJF	protein tyrosine phosphatase
MB46_17070	ENOG4105CFG	Acts as a chaperone (By similarity)
MB46_17075	ENOG4108093	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MB46_17080	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
MB46_17085	ENOG4105KNI	merR family transcriptional Regulator
MB46_17095	ENOG4105WBN	Transcriptional regulator (LacI family
MB46_17115	ENOG4105DRS	transport system, permease
MB46_17125	ENOG4105C0D	helicase
MB46_17135	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
MB46_17140	ENOG4105C1J	atp-dependent rna helicase
MB46_17150	ENOG4105JAB	phenazine biosynthesis protein, phzf family
MB46_17155	ENOG41090B9	response to stress
MB46_17165	ENOG410901E	Membrane
MB46_17185	ENOG4108S01	response regulator
MB46_17190	ENOG4105BZU	Histidine kinase
MB46_17215	ENOG4107UA9	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) (By similarity)
MB46_17225	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
MB46_17240	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
MB46_17280	ENOG4105C12	Phosphoribosylglycinamide synthetase
MB46_17285	ENOG4105C8V	SAICAR synthetase
MB46_17300	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
MB46_17310	ENOG4107RGJ	metallophosphoesterase
MB46_17315	ENOG4105BZ4	penicillin-binding protein
MB46_17340	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
MB46_17345	ENOG4105MVE	transcriptional regulator
MB46_17350	ENOG4105I1K	ABC transporter
MB46_17355	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
MB46_17360	ENOG4105EPJ	extracellular solute-binding protein family 1
MB46_17370	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
MB46_17425	ENOG4108I5C	dEAD DEAH box helicase
MB46_17435	ENOG4105C72	UPF0176 protein
MB46_17445	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
MB46_17450	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
MB46_17455	ENOG4107R33	ppx gppa phosphatase
MB46_17460	ENOG4105EY0	Xylose isomerase domain protein TIM barrel
MB46_17480	ENOG4105CH2	amidohydrolase
MB46_17485	ENOG4105FKN	transcriptional regulator, AsnC family
MB46_17490	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
MB46_17500	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
MB46_17510	ENOG4105CZN	Potassium uptake protein
MB46_17515	ENOG4105DGU	Histone deacetylase
MB46_17525	ENOG41080HT	Transcriptional regulator, arsr family
MB46_17530	ENOG4105D82	Glutamate dehydrogenase
MB46_17540	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
MB46_17545	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
MB46_17560	ENOG4107TDE	lipolytic protein G-D-S-L family
MB46_17565	ENOG4105CX8	fg-gap repeat protein
MB46_17600	ENOG4105DET	Rhamnulokinase
MB46_17605	ENOG4105C85	amino acid
MB46_17615	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
MB46_17620	ENOG4105ETE	Transcriptional regulator (LacI family
MB46_17625	ENOG4105DDC	Oxidoreductase domain protein
MB46_17640	ENOG4105DIA	mandelate racemase muconate lactonizing
MB46_17665	ENOG4105DIA	mandelate racemase muconate lactonizing
MB46_17670	ENOG410769Z	extracellular solute-binding protein family 1
MB46_17710	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
MB46_17715	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
MB46_17720	ENOG4105ETE	Transcriptional regulator (LacI family
MB46_17725	ENOG4105I82	acetyl xylan esterase
MB46_17730	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
MB46_17740	ENOG4108RXW	HAD-superfamily subfamily IB hydrolase
MB46_17750	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
MB46_17765	ENOG4108YYC	ycei family
MB46_17770	ENOG4108RH7	phosphoglycerate mutase
MB46_17780	ENOG4107QIV	Cytochrome c biogenesis protein
MB46_17785	ENOG4105EBH	Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment (By similarity)
MB46_17790	ENOG4105CRE	cytochrome C
MB46_17825	ENOG4105ETE	Transcriptional regulator (LacI family
MB46_17835	ENOG4105EQ7	Binding-protein-dependent transport systems, inner membrane component
MB46_17840	ENOG4105EG2	ABC transporter, permease
MB46_17875	ENOG4105CI2	imidazolone-5-propionate hydrolase
MB46_17930	ENOG4105VUN	Transcriptional regulator
MB46_18045	ENOG4105EQK	-acetyltransferase
MB46_18090	ENOG41062D9	Histidine kinase
MB46_18095	ENOG4105ETX	regulatoR
MB46_18100	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
MB46_18105	ENOG4108IAJ	Nad-dependent epimerase dehydratase
MB46_18180	ENOG4105BZ1	(ABC) transporter
MB46_18185	ENOG4108M8W	Monooxygenase
MB46_18190	ENOG4105CN5	Metallo-Beta-Lactamase
MB46_18210	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
MB46_18215	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
MB46_18230	ENOG4105ETE	Transcriptional regulator (LacI family
MB46_18240	ENOG4105HS6	binding-protein-dependent transport systems inner membrane Component
MB46_18245	ENOG4105EG2	ABC transporter, permease
MB46_18250	ENOG4105CK5	oxidoreductase
MB46_18260	ENOG4108MR6	WD40-like Beta Propeller Repeat
MB46_18265	ENOG4105C0H	protease
MB46_18275	ENOG4107R9S	Malate synthase
MB46_18300	ENOG4105QPS	Monooxygenase
MB46_18315	ENOG4105CIS	alcohol dehydrogenase
MB46_18340	ENOG4107RM1	amidohydrolase
MB46_18345	ENOG4105QEK	Transcriptional regulator
MB46_18350	ENOG4107TXC	Transcriptional regulator
MB46_18365	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
MB46_18425	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
MB46_18435	ENOG4105VBF	alkaline shock protein
MB46_18495	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
MB46_18505	ENOG4108HJF	gCN5-related N-acetyltransferase
MB46_18520	ENOG4108S0J	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized pyrimidines, such as thymine glycol, 5,6-dihydrouracil and 5,6-dihydrothymine. Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'- phosphates (By similarity)
MB46_18525	ENOG4107QRT	dEAD DEAH box helicase
MB46_18550	ENOG4105BZU	Histidine kinase
MB46_18555	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
MB46_18560	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
MB46_18710	ENOG4108Z6B	deaminase
MB46_18715	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
MB46_18745	ENOG4105M4E	phosphohistidine phosphatase, SixA
MB46_18750	ENOG4105ECB	domain protein
MB46_18760	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
MB46_18765	ENOG4105DKQ	ROK family
MB46_18770	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
MB46_18775	ENOG4108JQ7	(ABC) transporter
MB46_18790	ENOG4105DEF	Extracellular solute-binding protein, family 5
MB46_18795	ENOG41073TP	transcriptional regulator
MB46_18805	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
MB46_18810	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
MB46_18815	ENOG41081JD	Transcriptional regulator
MB46_18830	ENOG4105C9U	ATP-dependent DNA helicase RecQ
MB46_18845	ENOG4105DIA	mandelate racemase muconate lactonizing
MB46_18875	ENOG4105CNN	ABC, transporter
MB46_18880	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
MB46_18900	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
MB46_18920	ENOG4107YCY	Transcriptional regulator
MB46_18940	ENOG4105CGH	5'-nucleotidase
MB46_18955	ENOG4105D22	carbon starvation protein
MB46_18965	ENOG4108VC7	Protein of unknown function (DUF2587)
MB46_18985	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
MB46_19010	ENOG4105C6E	dna polymerase iii
MB46_19015	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
MB46_19025	ENOG4105TT9	Protein of unknown function (DUF2516)
MB46_19030	ENOG4107ZY0	Phenazine biosynthesis-like protein
MB46_19040	ENOG4107RPC	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
MB46_19045	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
MB46_19070	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
MB46_19075	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
MB46_19080	ENOG4105C8N	cysteinyl-tRNA synthetase
MB46_19085	ENOG4105C2N	RNA methyltransferase TrmH family group 3
MB46_19100	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
MB46_19110	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
MB46_19190	ENOG4107Z6X	Transcriptional regulator
MB46_19200	ENOG4105TVB	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
MB46_19300	ENOG4108RAV	Conserved protein
MB46_19340	ENOG410836F	Transposase
MB46_19370	ENOG4105C5I	Dehydrogenase
MB46_19375	ENOG4105DRS	transport system, permease
MB46_19380	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
MB46_19435	ENOG4105QCJ	Lipoprotein
MB46_19490	ENOG4107QJE	Chromosome Partitioning Protein
MB46_19660	ENOG41067RQ	csbd family
MB46_19670	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
MB46_19705	ENOG4105HRU	Glyoxalase Bleomycin resistance protein (Dioxygenase
MB46_19710	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
MB46_19720	ENOG4105F9F	transposase
MB46_19745	ENOG4105D6Z	AFG1 family ATPase
MB46_19765	ENOG4108C33	Resolvase
MB46_19785	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
MB46_19825	ENOG4105IYK	transposase
MB46_19835	ENOG4105CIS	alcohol dehydrogenase
MB46_19850	ENOG4105MSB	protein, conserved in bacteria
MB46_19940	ENOG4105FA0	parb-like partition protein
MB46_19990	ENOG4107Z6X	Transcriptional regulator
MB46_20000	ENOG4105TVB	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)