MB46_11665 5c3a4c01d420417fc4092a2dbab9361a 337 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 59 189 2.5E-63 T 14-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 MB46_11665 5c3a4c01d420417fc4092a2dbab9361a 337 Gene3D G3DSA:3.40.50.300 24 220 3.9E-46 T 14-10-2018 MB46_11665 5c3a4c01d420417fc4092a2dbab9361a 337 PIRSF PIRSF002849 1 337 1.0E-129 T 14-10-2018 MB46_11665 5c3a4c01d420417fc4092a2dbab9361a 337 Gene3D G3DSA:1.10.8.300 225 333 1.6E-31 T 14-10-2018 MB46_11665 5c3a4c01d420417fc4092a2dbab9361a 337 SUPERFAMILY SSF52540 30 312 3.41E-43 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_01930 7f2aefc8f44eb6f8ad3a1ef1002653bb 115 PIRSF PIRSF000178 1 108 2.2E-8 T 14-10-2018 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MB46_01930 7f2aefc8f44eb6f8ad3a1ef1002653bb 115 TIGRFAM TIGR02970 succ_dehyd_cytB: succinate dehydrogenase, cytochrome b556 subunit 1 99 6.1E-26 T 14-10-2018 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MB46_01930 7f2aefc8f44eb6f8ad3a1ef1002653bb 115 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 1 96 1.0E-19 T 14-10-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MB46_01930 7f2aefc8f44eb6f8ad3a1ef1002653bb 115 SUPERFAMILY SSF81343 1 102 1.07E-23 T 14-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MB46_01930 7f2aefc8f44eb6f8ad3a1ef1002653bb 115 Gene3D G3DSA:1.20.1300.10 1 107 1.1E-15 T 14-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MB46_12375 07ac9cd657a97718584217caaf42ce2e 427 Gene3D G3DSA:3.10.580.10 278 407 2.4E-29 T 14-10-2018 MB46_12375 07ac9cd657a97718584217caaf42ce2e 427 Gene3D G3DSA:1.25.60.10 156 277 4.1E-23 T 14-10-2018 IPR038076 MgtE, N-terminal domain superfamily MB46_12375 07ac9cd657a97718584217caaf42ce2e 427 Pfam PF05239 PRC-barrel domain 7 73 1.5E-4 T 14-10-2018 IPR027275 PRC-barrel domain MB46_12375 07ac9cd657a97718584217caaf42ce2e 427 SUPERFAMILY SSF54631 281 420 2.02E-24 T 14-10-2018 MB46_12375 07ac9cd657a97718584217caaf42ce2e 427 Pfam PF00571 CBS domain 356 406 6.0E-8 T 14-10-2018 IPR000644 CBS domain MB46_12375 07ac9cd657a97718584217caaf42ce2e 427 SMART SM00116 358 406 0.0012 T 14-10-2018 IPR000644 CBS domain MB46_12375 07ac9cd657a97718584217caaf42ce2e 427 SMART SM00924 179 282 6.8E-33 T 14-10-2018 IPR006668 Magnesium transporter, MgtE intracellular domain MB46_12375 07ac9cd657a97718584217caaf42ce2e 427 SUPERFAMILY SSF158791 164 279 4.97E-28 T 14-10-2018 MB46_12375 07ac9cd657a97718584217caaf42ce2e 427 Pfam PF03448 MgtE intracellular N domain 180 279 3.0E-25 T 14-10-2018 IPR006668 Magnesium transporter, MgtE intracellular domain MB46_06015 1893eeb4cbf59f1adc85ebfcc6a82af1 288 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 81 275 2.1E-15 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_06015 1893eeb4cbf59f1adc85ebfcc6a82af1 288 SUPERFAMILY SSF161098 47 268 1.7E-49 T 14-10-2018 IPR035906 MetI-like superfamily MB46_06015 1893eeb4cbf59f1adc85ebfcc6a82af1 288 Gene3D G3DSA:1.10.3720.10 42 281 1.8E-58 T 14-10-2018 IPR035906 MetI-like superfamily MB46_04560 08d38a53d1905788082bdd3ad465a9e9 313 Pfam PF02645 Uncharacterised protein, DegV family COG1307 28 309 3.5E-64 T 14-10-2018 IPR003797 DegV MB46_04560 08d38a53d1905788082bdd3ad465a9e9 313 Gene3D G3DSA:3.40.50.10170 25 180 1.1E-42 T 14-10-2018 MB46_04560 08d38a53d1905788082bdd3ad465a9e9 313 SUPERFAMILY SSF82549 28 309 3.4E-63 T 14-10-2018 MB46_04560 08d38a53d1905788082bdd3ad465a9e9 313 Gene3D G3DSA:3.30.1180.10 181 310 4.7E-30 T 14-10-2018 MB46_04560 08d38a53d1905788082bdd3ad465a9e9 313 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 29 309 4.5E-69 T 14-10-2018 IPR003797 DegV MB46_18745 c4cef4c0aa833431568c344f6a6ce50f 173 Gene3D G3DSA:3.40.50.1240 1 173 1.0E-41 T 14-10-2018 IPR029033 Histidine phosphatase superfamily MB46_18745 c4cef4c0aa833431568c344f6a6ce50f 173 SUPERFAMILY SSF53254 7 158 1.76E-22 T 14-10-2018 IPR029033 Histidine phosphatase superfamily MB46_18745 c4cef4c0aa833431568c344f6a6ce50f 173 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 9 83 7.8E-8 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MB46_17955 8742500526ff5c81a30a31744b55ca31 132 SUPERFAMILY SSF52799 36 129 1.0E-16 T 14-10-2018 IPR029021 Protein-tyrosine phosphatase-like MB46_17955 8742500526ff5c81a30a31744b55ca31 132 Gene3D G3DSA:3.90.190.10 32 132 3.5E-16 T 14-10-2018 IPR029021 Protein-tyrosine phosphatase-like MB46_17220 53b3158b238b43254e24156d74975548 259 SUPERFAMILY SSF89082 168 257 9.81E-14 T 14-10-2018 IPR036244 TipA-like multidrug resistance regulator, antibiotic-recognition domain MB46_17220 53b3158b238b43254e24156d74975548 259 Pfam PF13411 MerR HTH family regulatory protein 11 76 4.7E-14 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MB46_17220 53b3158b238b43254e24156d74975548 259 Gene3D G3DSA:1.10.1660.10 8 143 1.8E-34 T 14-10-2018 MB46_17220 53b3158b238b43254e24156d74975548 259 Pfam PF07739 TipAS antibiotic-recognition domain 134 254 2.1E-24 T 14-10-2018 IPR012925 TipAS antibiotic-recognition domain MB46_17220 53b3158b238b43254e24156d74975548 259 SMART SM00422 10 79 2.3E-17 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MB46_17220 53b3158b238b43254e24156d74975548 259 SUPERFAMILY SSF46955 10 111 8.06E-23 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily MB46_17220 53b3158b238b43254e24156d74975548 259 Gene3D G3DSA:1.10.490.50 154 258 8.2E-9 T 14-10-2018 IPR036244 TipA-like multidrug resistance regulator, antibiotic-recognition domain MB46_17595 7b4376486811cfe9ee752346cb6c8220 693 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 563 571 5.4E-5 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_17595 7b4376486811cfe9ee752346cb6c8220 693 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 509 520 5.4E-5 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_17595 7b4376486811cfe9ee752346cb6c8220 693 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 583 602 5.4E-5 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_17595 7b4376486811cfe9ee752346cb6c8220 693 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 604 621 3.8E-24 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_17595 7b4376486811cfe9ee752346cb6c8220 693 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 557 573 3.8E-24 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_17595 7b4376486811cfe9ee752346cb6c8220 693 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 509 520 3.8E-24 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_17595 7b4376486811cfe9ee752346cb6c8220 693 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 651 671 3.8E-24 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_17595 7b4376486811cfe9ee752346cb6c8220 693 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 436 453 3.8E-24 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_17595 7b4376486811cfe9ee752346cb6c8220 693 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 583 602 3.8E-24 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_17595 7b4376486811cfe9ee752346cb6c8220 693 SMART SM01007 23 225 6.0E-34 T 14-10-2018 IPR001303 Class II aldolase/adducin N-terminal MB46_17595 7b4376486811cfe9ee752346cb6c8220 693 Gene3D G3DSA:3.40.50.720 417 690 3.1E-62 T 14-10-2018 MB46_17595 7b4376486811cfe9ee752346cb6c8220 693 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 441 687 1.6E-49 T 14-10-2018 MB46_17595 7b4376486811cfe9ee752346cb6c8220 693 SUPERFAMILY SSF53639 29 230 3.34E-29 T 14-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily MB46_17595 7b4376486811cfe9ee752346cb6c8220 693 Gene3D G3DSA:3.40.225.10 20 230 1.9E-47 T 14-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily MB46_17595 7b4376486811cfe9ee752346cb6c8220 693 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 29 225 1.6E-21 T 14-10-2018 IPR001303 Class II aldolase/adducin N-terminal MB46_17595 7b4376486811cfe9ee752346cb6c8220 693 SUPERFAMILY SSF51735 435 687 3.98E-62 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_17595 7b4376486811cfe9ee752346cb6c8220 693 TIGRFAM TIGR02632 RhaD_aldol-ADH: rhamnulose-1-phosphate aldolase/alcohol dehydrogenase 22 693 2.1E-303 T 14-10-2018 IPR013454 Bifunctional rhamnulose-1-phosphate aldolase/alcohol dehydrogenase MB46_16465 f1c9a661cf1a601bd1c7686a4429cee0 468 SUPERFAMILY SSF53067 240 454 8.46E-41 T 14-10-2018 MB46_16465 f1c9a661cf1a601bd1c7686a4429cee0 468 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 246 429 2.6E-28 T 14-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 MB46_16465 f1c9a661cf1a601bd1c7686a4429cee0 468 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 5 237 5.9E-40 T 14-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 MB46_16465 f1c9a661cf1a601bd1c7686a4429cee0 468 Gene3D G3DSA:3.30.420.40 2 238 1.8E-68 T 14-10-2018 MB46_16465 f1c9a661cf1a601bd1c7686a4429cee0 468 PIRSF PIRSF000538 3 442 2.8E-78 T 14-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 MB46_16465 f1c9a661cf1a601bd1c7686a4429cee0 468 SUPERFAMILY SSF53067 5 238 5.31E-45 T 14-10-2018 MB46_16465 f1c9a661cf1a601bd1c7686a4429cee0 468 TIGRFAM TIGR01312 XylB: xylulokinase 7 431 7.1E-118 T 14-10-2018 IPR006000 Xylulokinase GO:0004856|GO:0005997 KEGG: 00040+2.7.1.17 MB46_16465 f1c9a661cf1a601bd1c7686a4429cee0 468 Gene3D G3DSA:3.30.420.40 240 465 3.5E-63 T 14-10-2018 MB46_13495 bca078d7913794c83aae4e6d2b058c6a 124 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 58 124 7.9E-28 T 14-10-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_13495 bca078d7913794c83aae4e6d2b058c6a 124 TIGRFAM TIGR00855 L12: ribosomal protein bL12 1 124 1.5E-44 T 14-10-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_13495 bca078d7913794c83aae4e6d2b058c6a 124 SUPERFAMILY SSF48300 5 60 4.58E-14 T 14-10-2018 IPR036235 Ribosomal protein L7/L12, oligomerisation domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_13495 bca078d7913794c83aae4e6d2b058c6a 124 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 5 51 9.2E-15 T 14-10-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_13495 bca078d7913794c83aae4e6d2b058c6a 124 Gene3D G3DSA:3.30.1390.10 55 124 2.7E-29 T 14-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like MB46_13495 bca078d7913794c83aae4e6d2b058c6a 124 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 3 124 23.117 T 14-10-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_13495 bca078d7913794c83aae4e6d2b058c6a 124 Gene3D G3DSA:1.20.5.710 4 54 3.5E-15 T 14-10-2018 MB46_13495 bca078d7913794c83aae4e6d2b058c6a 124 SUPERFAMILY SSF54736 54 124 4.01E-23 T 14-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like MB46_13495 bca078d7913794c83aae4e6d2b058c6a 124 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 59 98 6.0E-13 T 14-10-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_14710 90f940aedc1e594868bc4e01341483fc 428 SUPERFAMILY SSF55021 257 335 3.62E-15 T 14-10-2018 MB46_14710 90f940aedc1e594868bc4e01341483fc 428 Gene3D G3DSA:3.40.1160.10 1 254 1.7E-90 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily MB46_14710 90f940aedc1e594868bc4e01341483fc 428 Gene3D G3DSA:3.30.2130.10 255 428 5.7E-59 T 14-10-2018 MB46_14710 90f940aedc1e594868bc4e01341483fc 428 PIRSF PIRSF000726 1 61 1.2E-18 T 14-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 MB46_14710 90f940aedc1e594868bc4e01341483fc 428 PIRSF PIRSF000726 54 421 2.4E-119 T 14-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 MB46_14710 90f940aedc1e594868bc4e01341483fc 428 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 14-10-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 MB46_14710 90f940aedc1e594868bc4e01341483fc 428 Pfam PF13840 ACT domain 348 409 7.4E-9 T 14-10-2018 IPR027795 CASTOR, ACT domain MB46_14710 90f940aedc1e594868bc4e01341483fc 428 SUPERFAMILY SSF55021 340 416 3.5E-21 T 14-10-2018 MB46_14710 90f940aedc1e594868bc4e01341483fc 428 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 63 412 1.0E-109 T 14-10-2018 IPR001341 Aspartate kinase GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 MB46_14710 90f940aedc1e594868bc4e01341483fc 428 Pfam PF00696 Amino acid kinase family 3 231 5.1E-54 T 14-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 MB46_14710 90f940aedc1e594868bc4e01341483fc 428 SUPERFAMILY SSF53633 4 244 5.5E-74 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily MB46_15995 4d09fe5b949fc177a63c83ecb003814f 234 SUPERFAMILY SSF52540 4 222 3.13E-65 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_15995 4d09fe5b949fc177a63c83ecb003814f 234 Gene3D G3DSA:3.40.50.300 2 228 1.9E-66 T 14-10-2018 MB46_15995 4d09fe5b949fc177a63c83ecb003814f 234 SMART SM00382 32 227 6.7E-17 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_15995 4d09fe5b949fc177a63c83ecb003814f 234 Pfam PF00005 ABC transporter 23 172 6.8E-33 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_15995 4d09fe5b949fc177a63c83ecb003814f 234 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_08460 bfc6a17db2c8c066080d59b12368acf7 204 Gene3D G3DSA:3.30.63.10 49 109 2.4E-56 T 14-10-2018 MB46_08460 bfc6a17db2c8c066080d59b12368acf7 204 Pfam PF00625 Guanylate kinase 21 196 4.7E-39 T 14-10-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit MB46_08460 bfc6a17db2c8c066080d59b12368acf7 204 SMART SM00072 18 200 4.2E-55 T 14-10-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit MB46_08460 bfc6a17db2c8c066080d59b12368acf7 204 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 20 195 5.1E-64 T 14-10-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 MB46_08460 bfc6a17db2c8c066080d59b12368acf7 204 Gene3D G3DSA:3.40.50.300 22 194 2.4E-56 T 14-10-2018 MB46_08460 bfc6a17db2c8c066080d59b12368acf7 204 SUPERFAMILY SSF52540 20 196 1.31E-55 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_08460 bfc6a17db2c8c066080d59b12368acf7 204 Hamap MF_00328 Guanylate kinase [gmk]. 16 200 33.773 T 14-10-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 MB46_08460 bfc6a17db2c8c066080d59b12368acf7 204 ProSitePatterns PS00856 Guanylate kinase-like signature. 52 69 - T 14-10-2018 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 MB46_12055 1feac851154ab91345cc6fe72bb1f7c3 351 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 14 350 3.3E-117 T 14-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 MB46_12055 1feac851154ab91345cc6fe72bb1f7c3 351 ProSitePatterns PS00907 Uroporphyrinogen decarboxylase signature 2. 149 165 - T 14-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 MB46_12055 1feac851154ab91345cc6fe72bb1f7c3 351 Gene3D G3DSA:3.20.20.210 5 351 4.8E-137 T 14-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 MB46_12055 1feac851154ab91345cc6fe72bb1f7c3 351 TIGRFAM TIGR01464 hemE: uroporphyrinogen decarboxylase 19 350 1.2E-108 T 14-10-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 MB46_12055 1feac851154ab91345cc6fe72bb1f7c3 351 ProSitePatterns PS00906 Uroporphyrinogen decarboxylase signature 1. 32 41 - T 14-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 MB46_12055 1feac851154ab91345cc6fe72bb1f7c3 351 SUPERFAMILY SSF51726 14 350 1.13E-96 T 14-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 MB46_12055 1feac851154ab91345cc6fe72bb1f7c3 351 Hamap MF_00218 Uroporphyrinogen decarboxylase [hemE]. 16 351 41.747 T 14-10-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 MB46_00510 552501ab1eb6c8ffd7a9602f7ec30872 350 Pfam PF00742 Homoserine dehydrogenase 159 337 2.0E-53 T 14-10-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 MB46_00510 552501ab1eb6c8ffd7a9602f7ec30872 350 SUPERFAMILY SSF55347 159 324 1.44E-45 T 14-10-2018 MB46_00510 552501ab1eb6c8ffd7a9602f7ec30872 350 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 204 226 - T 14-10-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 MB46_00510 552501ab1eb6c8ffd7a9602f7ec30872 350 Gene3D G3DSA:3.40.50.720 6 337 1.2E-89 T 14-10-2018 MB46_00510 552501ab1eb6c8ffd7a9602f7ec30872 350 PIRSF PIRSF036497 1 345 1.3E-97 T 14-10-2018 IPR022697 Homoserine dehydrogenase lacking ACT domain GO:0004412 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 MB46_00510 552501ab1eb6c8ffd7a9602f7ec30872 350 SUPERFAMILY SSF51735 1 180 7.35E-21 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_00510 552501ab1eb6c8ffd7a9602f7ec30872 350 Gene3D G3DSA:3.30.360.10 170 320 1.2E-89 T 14-10-2018 MB46_08445 e505452854a2c4bb919e1a574ab4c076 400 Gene3D G3DSA:3.30.300.10 9 248 5.4E-162 T 14-10-2018 MB46_08445 e505452854a2c4bb919e1a574ab4c076 400 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 130 140 - T 14-10-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MB46_08445 e505452854a2c4bb919e1a574ab4c076 400 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 9 396 2.8E-163 T 14-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MB46_08445 e505452854a2c4bb919e1a574ab4c076 400 PIRSF PIRSF000497 2 399 5.3E-161 T 14-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MB46_08445 e505452854a2c4bb919e1a574ab4c076 400 Gene3D G3DSA:3.30.300.10 106 389 5.4E-162 T 14-10-2018 MB46_08445 e505452854a2c4bb919e1a574ab4c076 400 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 248 386 9.3E-65 T 14-10-2018 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MB46_08445 e505452854a2c4bb919e1a574ab4c076 400 Pfam PF02772 S-adenosylmethionine synthetase, central domain 129 246 7.1E-40 T 14-10-2018 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MB46_08445 e505452854a2c4bb919e1a574ab4c076 400 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 6 398 53.611 T 14-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MB46_08445 e505452854a2c4bb919e1a574ab4c076 400 Gene3D G3DSA:3.30.300.10 15 285 5.4E-162 T 14-10-2018 MB46_08445 e505452854a2c4bb919e1a574ab4c076 400 SUPERFAMILY SSF55973 9 112 1.77E-43 T 14-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MB46_08445 e505452854a2c4bb919e1a574ab4c076 400 SUPERFAMILY SSF55973 248 399 2.08E-65 T 14-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MB46_08445 e505452854a2c4bb919e1a574ab4c076 400 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 9 104 4.6E-41 T 14-10-2018 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MB46_08445 e505452854a2c4bb919e1a574ab4c076 400 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 274 282 - T 14-10-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MB46_08445 e505452854a2c4bb919e1a574ab4c076 400 SUPERFAMILY SSF55973 126 247 2.35E-43 T 14-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MB46_12475 fd4ba461112aae175ec25e6fb68c2e92 329 Hamap MF_02122 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase [dapD]. 9 327 43.237 T 14-10-2018 IPR026586 Type 2 tetrahydrodipicolinate N-succinyltransferase family GO:0008666 KEGG: 00300+2.3.1.117 MB46_12475 fd4ba461112aae175ec25e6fb68c2e92 329 TIGRFAM TIGR03535 DapD_actino: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase 10 329 1.3E-155 T 14-10-2018 IPR019875 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, actinobacteria KEGG: 00300+2.3.1.117 MB46_12475 fd4ba461112aae175ec25e6fb68c2e92 329 Pfam PF14789 Tetrahydrodipicolinate N-succinyltransferase middle 114 153 1.4E-18 T 14-10-2018 IPR032784 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, middle domain KEGG: 00300+2.3.1.117 MB46_12475 fd4ba461112aae175ec25e6fb68c2e92 329 Gene3D G3DSA:3.30.70.2010 5 113 3.0E-34 T 14-10-2018 MB46_12475 fd4ba461112aae175ec25e6fb68c2e92 329 Gene3D G3DSA:3.30.60.70 114 153 1.4E-23 T 14-10-2018 IPR038361 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, middle domain superfamily KEGG: 00300+2.3.1.117 MB46_12475 fd4ba461112aae175ec25e6fb68c2e92 329 SUPERFAMILY SSF51161 77 307 9.84E-39 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily MB46_12475 fd4ba461112aae175ec25e6fb68c2e92 329 Gene3D G3DSA:2.160.10.10 154 329 1.1E-66 T 14-10-2018 MB46_12475 fd4ba461112aae175ec25e6fb68c2e92 329 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 235 267 8.3E-13 T 14-10-2018 IPR001451 Hexapeptide repeat MB46_03200 1500ec41b3f5e9a5d0a6d8037d09a540 365 SUPERFAMILY SSF53474 6 360 2.89E-82 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_03200 1500ec41b3f5e9a5d0a6d8037d09a540 365 Gene3D G3DSA:3.40.50.1820 13 357 5.4E-125 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_03200 1500ec41b3f5e9a5d0a6d8037d09a540 365 Gene3D G3DSA:1.10.1740.110 169 284 5.4E-125 T 14-10-2018 MB46_03200 1500ec41b3f5e9a5d0a6d8037d09a540 365 TIGRFAM TIGR01392 homoserO_Ac_trn: homoserine O-acetyltransferase 9 360 6.9E-125 T 14-10-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 MB46_03200 1500ec41b3f5e9a5d0a6d8037d09a540 365 PIRSF PIRSF000443 2 362 9.6E-117 T 14-10-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 MB46_03200 1500ec41b3f5e9a5d0a6d8037d09a540 365 Hamap MF_00296 Homoserine O-acetyltransferase [metXA]. 4 363 28.529 T 14-10-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 MB46_03200 1500ec41b3f5e9a5d0a6d8037d09a540 365 Pfam PF00561 alpha/beta hydrolase fold 37 350 5.4E-31 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MB46_10495 b7f2cfd26fe9a7903be81c5e6eaf6c12 1090 Gene3D G3DSA:3.30.70.1440 675 867 2.1E-265 T 14-10-2018 MB46_10495 b7f2cfd26fe9a7903be81c5e6eaf6c12 1090 PRINTS PR00702 Acriflavin resistance protein family signature 463 486 6.4E-43 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MB46_10495 b7f2cfd26fe9a7903be81c5e6eaf6c12 1090 PRINTS PR00702 Acriflavin resistance protein family signature 438 461 6.4E-43 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MB46_10495 b7f2cfd26fe9a7903be81c5e6eaf6c12 1090 PRINTS PR00702 Acriflavin resistance protein family signature 357 378 6.4E-43 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MB46_10495 b7f2cfd26fe9a7903be81c5e6eaf6c12 1090 PRINTS PR00702 Acriflavin resistance protein family signature 385 409 6.4E-43 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MB46_10495 b7f2cfd26fe9a7903be81c5e6eaf6c12 1090 PRINTS PR00702 Acriflavin resistance protein family signature 39 57 6.4E-43 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MB46_10495 b7f2cfd26fe9a7903be81c5e6eaf6c12 1090 PRINTS PR00702 Acriflavin resistance protein family signature 330 353 6.4E-43 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MB46_10495 b7f2cfd26fe9a7903be81c5e6eaf6c12 1090 SUPERFAMILY SSF82866 808 1038 4.19E-47 T 14-10-2018 MB46_10495 b7f2cfd26fe9a7903be81c5e6eaf6c12 1090 Gene3D G3DSA:3.30.70.1320 133 326 2.1E-265 T 14-10-2018 MB46_10495 b7f2cfd26fe9a7903be81c5e6eaf6c12 1090 Gene3D G3DSA:3.30.70.1430 41 818 2.1E-265 T 14-10-2018 MB46_10495 b7f2cfd26fe9a7903be81c5e6eaf6c12 1090 SUPERFAMILY SSF82714 183 263 1.31E-7 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MB46_10495 b7f2cfd26fe9a7903be81c5e6eaf6c12 1090 SUPERFAMILY SSF82693 135 323 6.8E-11 T 14-10-2018 MB46_10495 b7f2cfd26fe9a7903be81c5e6eaf6c12 1090 SUPERFAMILY SSF82693 41 128 4.71E-22 T 14-10-2018 MB46_10495 b7f2cfd26fe9a7903be81c5e6eaf6c12 1090 SUPERFAMILY SSF82866 292 491 7.32E-46 T 14-10-2018 MB46_10495 b7f2cfd26fe9a7903be81c5e6eaf6c12 1090 Gene3D G3DSA:3.30.2090.10 177 269 2.1E-265 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MB46_10495 b7f2cfd26fe9a7903be81c5e6eaf6c12 1090 SUPERFAMILY SSF82693 577 667 7.59E-7 T 14-10-2018 MB46_10495 b7f2cfd26fe9a7903be81c5e6eaf6c12 1090 Gene3D G3DSA:1.20.1640.10 13 507 2.1E-265 T 14-10-2018 MB46_10495 b7f2cfd26fe9a7903be81c5e6eaf6c12 1090 Gene3D G3DSA:1.20.1640.10 523 1030 2.1E-265 T 14-10-2018 MB46_10495 b7f2cfd26fe9a7903be81c5e6eaf6c12 1090 Pfam PF00873 AcrB/AcrD/AcrF family 5 1033 2.6E-211 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MB46_10495 b7f2cfd26fe9a7903be81c5e6eaf6c12 1090 Gene3D G3DSA:3.30.70.1430 577 674 2.1E-265 T 14-10-2018 MB46_10495 b7f2cfd26fe9a7903be81c5e6eaf6c12 1090 SUPERFAMILY SSF82714 725 807 3.01E-9 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MB46_10495 b7f2cfd26fe9a7903be81c5e6eaf6c12 1090 Gene3D G3DSA:3.30.2090.10 724 810 2.1E-265 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MB46_12730 befa3c6a2f1842dd8a8770756d3abebf 210 Pfam PF00881 Nitroreductase family 30 188 6.0E-14 T 14-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 MB46_12730 befa3c6a2f1842dd8a8770756d3abebf 210 SUPERFAMILY SSF55469 25 207 2.49E-35 T 14-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MB46_12730 befa3c6a2f1842dd8a8770756d3abebf 210 Gene3D G3DSA:3.40.109.10 13 207 3.7E-25 T 14-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MB46_16600 952ab9600eaec40fbf7c2c8d8ad11706 252 Pfam PF01925 Sulfite exporter TauE/SafE 7 247 9.7E-38 T 14-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 MB46_13810 3cef82153d6b1d585b57d1ec892a8249 324 SUPERFAMILY SSF46689 263 315 8.71E-9 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MB46_13810 3cef82153d6b1d585b57d1ec892a8249 324 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 280 295 2.7E-5 T 14-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 MB46_13810 3cef82153d6b1d585b57d1ec892a8249 324 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 295 311 2.7E-5 T 14-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 MB46_13810 3cef82153d6b1d585b57d1ec892a8249 324 Gene3D G3DSA:1.10.10.60 205 323 2.5E-23 T 14-10-2018 MB46_13810 3cef82153d6b1d585b57d1ec892a8249 324 Pfam PF14525 AraC-binding-like domain 32 194 1.0E-9 T 14-10-2018 IPR035418 Transcription regulator HTH, AraC- type, ligand binding domain-like MB46_13810 3cef82153d6b1d585b57d1ec892a8249 324 SMART SM00342 227 311 2.1E-15 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MB46_13810 3cef82153d6b1d585b57d1ec892a8249 324 Pfam PF12833 Helix-turn-helix domain 233 313 3.6E-16 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MB46_08335 fde699f93af49ed47bae631e505261a9 247 SUPERFAMILY SSF53474 18 243 1.89E-35 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_08335 fde699f93af49ed47bae631e505261a9 247 PIRSF PIRSF017388 2 245 4.0E-58 T 14-10-2018 IPR012354 Esterase/lipase GO:0052689 MB46_08335 fde699f93af49ed47bae631e505261a9 247 Pfam PF12146 Serine aminopeptidase, S33 18 226 2.4E-15 T 14-10-2018 IPR022742 Serine aminopeptidase, S33 MB46_08335 fde699f93af49ed47bae631e505261a9 247 Gene3D G3DSA:3.40.50.1820 6 244 2.4E-51 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_04085 4a94d2239373dd8ffe01af8ee8bf4188 182 SUPERFAMILY SSF52540 4 172 1.34E-16 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_04085 4a94d2239373dd8ffe01af8ee8bf4188 182 Gene3D G3DSA:3.40.50.300 3 180 5.4E-25 T 14-10-2018 MB46_17505 ba3574ad8204d6fe556667bc82a1332f 228 Gene3D G3DSA:3.30.70.1450 149 225 1.4E-15 T 14-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 MB46_17505 ba3574ad8204d6fe556667bc82a1332f 228 Gene3D G3DSA:3.40.50.720 13 148 2.9E-27 T 14-10-2018 MB46_17505 ba3574ad8204d6fe556667bc82a1332f 228 SUPERFAMILY SSF51735 17 144 1.93E-28 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_17505 ba3574ad8204d6fe556667bc82a1332f 228 Pfam PF02254 TrkA-N domain 17 132 3.8E-21 T 14-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 MB46_17505 ba3574ad8204d6fe556667bc82a1332f 228 SUPERFAMILY SSF116726 147 226 4.84E-13 T 14-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 MB46_15380 581328c41c96032a8bab6abfc250a7a0 232 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 153 221 1.1E-17 T 14-10-2018 IPR000032 Phosphocarrier protein HPr-like MB46_15380 581328c41c96032a8bab6abfc250a7a0 232 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 161 168 - T 14-10-2018 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site MB46_15380 581328c41c96032a8bab6abfc250a7a0 232 Gene3D G3DSA:3.40.50.510 1 128 3.1E-43 T 14-10-2018 IPR036662 Phosphotransferase system, mannose-type IIA component superfamily GO:0009401|GO:0016021 MB46_15380 581328c41c96032a8bab6abfc250a7a0 232 Gene3D G3DSA:3.30.1340.10 149 224 3.1E-18 T 14-10-2018 IPR035895 HPr-like superfamily MB46_15380 581328c41c96032a8bab6abfc250a7a0 232 SUPERFAMILY SSF55594 152 231 1.44E-17 T 14-10-2018 IPR035895 HPr-like superfamily MB46_15380 581328c41c96032a8bab6abfc250a7a0 232 PRINTS PR00107 Phosphocarrier protein signature 197 214 2.0E-10 T 14-10-2018 IPR000032 Phosphocarrier protein HPr-like MB46_15380 581328c41c96032a8bab6abfc250a7a0 232 PRINTS PR00107 Phosphocarrier protein signature 161 177 2.0E-10 T 14-10-2018 IPR000032 Phosphocarrier protein HPr-like MB46_15380 581328c41c96032a8bab6abfc250a7a0 232 PRINTS PR00107 Phosphocarrier protein signature 182 197 2.0E-10 T 14-10-2018 IPR000032 Phosphocarrier protein HPr-like MB46_15380 581328c41c96032a8bab6abfc250a7a0 232 TIGRFAM TIGR02364 dha_pts: dihydroxyacetone kinase, phosphotransfer subunit 3 121 1.1E-35 T 14-10-2018 IPR012844 Dihydroxyacetone kinase phosphotransferase subunit, N-terminal domain MB46_15380 581328c41c96032a8bab6abfc250a7a0 232 SUPERFAMILY SSF53062 1 124 2.35E-33 T 14-10-2018 IPR036662 Phosphotransferase system, mannose-type IIA component superfamily GO:0009401|GO:0016021 MB46_15380 581328c41c96032a8bab6abfc250a7a0 232 Pfam PF03610 PTS system fructose IIA component 4 113 3.5E-27 T 14-10-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 MB46_15380 581328c41c96032a8bab6abfc250a7a0 232 Pfam PF00381 PTS HPr component phosphorylation site 153 221 8.0E-19 T 14-10-2018 IPR000032 Phosphocarrier protein HPr-like MB46_08980 59da7653be0cbe180d35a466af8750f2 211 Gene3D G3DSA:1.20.1440.130 16 171 1.3E-14 T 14-10-2018 IPR038354 VKOR domain superfamily Reactome: R-HSA-6806664 MB46_08980 59da7653be0cbe180d35a466af8750f2 211 SMART SM00756 22 163 7.5E-45 T 14-10-2018 IPR012932 Vitamin K epoxide reductase Reactome: R-HSA-6806664 MB46_08980 59da7653be0cbe180d35a466af8750f2 211 Pfam PF07884 Vitamin K epoxide reductase family 28 159 2.4E-26 T 14-10-2018 IPR012932 Vitamin K epoxide reductase Reactome: R-HSA-6806664 MB46_12995 f42d83ddae5565205c9ce6c03f0d4434 301 Gene3D G3DSA:1.10.287.1060 1 92 3.3E-9 T 14-10-2018 MB46_07620 0a8c128cf92fe7d2c01f74eade9b5deb 1544 Gene3D G3DSA:3.20.20.70 822 1254 1.4E-189 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MB46_07620 0a8c128cf92fe7d2c01f74eade9b5deb 1544 SUPERFAMILY SSF69336 1252 1518 9.94E-87 T 14-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 MB46_07620 0a8c128cf92fe7d2c01f74eade9b5deb 1544 Gene3D G3DSA:3.20.20.70 459 821 2.5E-124 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MB46_07620 0a8c128cf92fe7d2c01f74eade9b5deb 1544 Gene3D G3DSA:2.160.20.60 1255 1526 2.0E-97 T 14-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 MB46_07620 0a8c128cf92fe7d2c01f74eade9b5deb 1544 SUPERFAMILY SSF51395 470 1236 1.1E-252 T 14-10-2018 MB46_07620 0a8c128cf92fe7d2c01f74eade9b5deb 1544 SUPERFAMILY SSF56235 40 460 2.88E-145 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MB46_07620 0a8c128cf92fe7d2c01f74eade9b5deb 1544 Pfam PF01645 Conserved region in glutamate synthase 839 1203 5.5E-153 T 14-10-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 MB46_07620 0a8c128cf92fe7d2c01f74eade9b5deb 1544 Pfam PF04898 Glutamate synthase central domain 483 774 1.7E-105 T 14-10-2018 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 MB46_07620 0a8c128cf92fe7d2c01f74eade9b5deb 1544 Pfam PF01493 GXGXG motif 1283 1455 2.6E-70 T 14-10-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0016491|GO:0055114 MB46_07620 0a8c128cf92fe7d2c01f74eade9b5deb 1544 Pfam PF00310 Glutamine amidotransferases class-II 40 456 7.9E-173 T 14-10-2018 IPR017932 Glutamine amidotransferase type 2 domain MB46_07620 0a8c128cf92fe7d2c01f74eade9b5deb 1544 Gene3D G3DSA:3.60.20.10 40 458 7.8E-170 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MB46_13210 a913df0ccc0aedb3a22d91fe05eacbed 359 Pfam PF01658 Myo-inositol-1-phosphate synthase 193 301 5.1E-31 T 14-10-2018 IPR013021 Myo-inositol-1-phosphate synthase, GAPDH-like KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 MB46_13210 a913df0ccc0aedb3a22d91fe05eacbed 359 TIGRFAM TIGR03450 mycothiol_INO1: inositol 1-phosphate synthase 6 355 1.3E-203 T 14-10-2018 IPR017815 Myo-inositol 1-phosphate synthase, actinobacteria MB46_13210 a913df0ccc0aedb3a22d91fe05eacbed 359 PIRSF PIRSF015578 1 355 1.8E-87 T 14-10-2018 IPR002587 Myo-inositol-1-phosphate synthase GO:0004512|GO:0006021|GO:0008654 KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 MB46_13210 a913df0ccc0aedb3a22d91fe05eacbed 359 SUPERFAMILY SSF51735 5 357 6.19E-89 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_13210 a913df0ccc0aedb3a22d91fe05eacbed 359 Gene3D G3DSA:3.30.360.10 192 301 2.5E-146 T 14-10-2018 MB46_13210 a913df0ccc0aedb3a22d91fe05eacbed 359 Gene3D G3DSA:3.40.50.720 6 354 2.5E-146 T 14-10-2018 MB46_13210 a913df0ccc0aedb3a22d91fe05eacbed 359 SUPERFAMILY SSF55347 192 300 5.63E-33 T 14-10-2018 MB46_06395 da635be6dd9604a7529c71bbda853605 3477 Gene3D G3DSA:3.30.559.30 224 443 7.4E-42 T 14-10-2018 MB46_06395 da635be6dd9604a7529c71bbda853605 3477 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2749 2760 - T 14-10-2018 IPR020845 AMP-binding, conserved site MB46_06395 da635be6dd9604a7529c71bbda853605 3477 Pfam PF00975 Thioesterase domain 3227 3371 3.1E-23 T 14-10-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 MB46_06395 da635be6dd9604a7529c71bbda853605 3477 Pfam PF00550 Phosphopantetheine attachment site 3139 3199 5.8E-11 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain MB46_06395 da635be6dd9604a7529c71bbda853605 3477 Pfam PF00550 Phosphopantetheine attachment site 2021 2083 2.5E-15 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain MB46_06395 da635be6dd9604a7529c71bbda853605 3477 Pfam PF00550 Phosphopantetheine attachment site 983 1045 2.5E-11 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain MB46_06395 da635be6dd9604a7529c71bbda853605 3477 SUPERFAMILY SSF52777 2120 2293 3.22E-43 T 14-10-2018 MB46_06395 da635be6dd9604a7529c71bbda853605 3477 Gene3D G3DSA:3.30.559.10 2120 2514 2.8E-130 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 MB46_06395 da635be6dd9604a7529c71bbda853605 3477 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1660 1671 - T 14-10-2018 IPR020845 AMP-binding, conserved site MB46_06395 da635be6dd9604a7529c71bbda853605 3477 SUPERFAMILY SSF56801 2594 3149 1.11E-121 T 14-10-2018 MB46_06395 da635be6dd9604a7529c71bbda853605 3477 Pfam PF13193 AMP-binding enzyme C-terminal domain 1926 1995 1.8E-8 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain MB46_06395 da635be6dd9604a7529c71bbda853605 3477 Pfam PF13193 AMP-binding enzyme C-terminal domain 885 958 1.1E-8 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain MB46_06395 da635be6dd9604a7529c71bbda853605 3477 Pfam PF13193 AMP-binding enzyme C-terminal domain 3024 3111 2.5E-6 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain MB46_06395 da635be6dd9604a7529c71bbda853605 3477 SUPERFAMILY SSF52777 1250 1503 1.45E-51 T 14-10-2018 MB46_06395 da635be6dd9604a7529c71bbda853605 3477 SUPERFAMILY SSF53474 3207 3467 1.12E-48 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_06395 da635be6dd9604a7529c71bbda853605 3477 SMART SM00823 Phosphopantetheine attachment site 3136 3205 0.0025 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MB46_06395 da635be6dd9604a7529c71bbda853605 3477 SMART SM00823 Phosphopantetheine attachment site 978 1050 7.0E-4 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MB46_06395 da635be6dd9604a7529c71bbda853605 3477 SMART SM00823 Phosphopantetheine attachment site 2019 2088 1.1E-9 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MB46_06395 da635be6dd9604a7529c71bbda853605 3477 Pfam PF00668 Condensation domain 2329 2586 4.4E-42 T 14-10-2018 IPR001242 Condensation domain MB46_06395 da635be6dd9604a7529c71bbda853605 3477 Pfam PF00668 Condensation domain 18 450 4.1E-42 T 14-10-2018 IPR001242 Condensation domain MB46_06395 da635be6dd9604a7529c71bbda853605 3477 Pfam PF00668 Condensation domain 1065 1512 4.6E-91 T 14-10-2018 IPR001242 Condensation domain MB46_06395 da635be6dd9604a7529c71bbda853605 3477 Pfam PF00668 Condensation domain 2117 2297 6.1E-33 T 14-10-2018 IPR001242 Condensation domain MB46_06395 da635be6dd9604a7529c71bbda853605 3477 SUPERFAMILY SSF52777 1067 1239 1.78E-49 T 14-10-2018 MB46_06395 da635be6dd9604a7529c71bbda853605 3477 SUPERFAMILY SSF52777 19 195 4.22E-31 T 14-10-2018 MB46_06395 da635be6dd9604a7529c71bbda853605 3477 SUPERFAMILY SSF47336 2013 2084 5.89E-19 T 14-10-2018 IPR036736 ACP-like superfamily MB46_06395 da635be6dd9604a7529c71bbda853605 3477 Gene3D G3DSA:1.10.1200.10 972 1051 1.5E-25 T 14-10-2018 IPR036736 ACP-like superfamily MB46_06395 da635be6dd9604a7529c71bbda853605 3477 Gene3D G3DSA:1.10.1200.10 2008 2089 5.4E-25 T 14-10-2018 IPR036736 ACP-like superfamily MB46_06395 da635be6dd9604a7529c71bbda853605 3477 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 491 901 1.3E-109 T 14-10-2018 IPR010071 Amino acid adenylation domain MB46_06395 da635be6dd9604a7529c71bbda853605 3477 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1553 1942 1.2E-100 T 14-10-2018 IPR010071 Amino acid adenylation domain MB46_06395 da635be6dd9604a7529c71bbda853605 3477 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2626 3039 7.7E-106 T 14-10-2018 IPR010071 Amino acid adenylation domain MB46_06395 da635be6dd9604a7529c71bbda853605 3477 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2043 2058 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site MB46_06395 da635be6dd9604a7529c71bbda853605 3477 SUPERFAMILY SSF56801 1490 2032 2.88E-126 T 14-10-2018 MB46_06395 da635be6dd9604a7529c71bbda853605 3477 SUPERFAMILY SSF47336 974 1046 9.03E-18 T 14-10-2018 IPR036736 ACP-like superfamily MB46_06395 da635be6dd9604a7529c71bbda853605 3477 Gene3D G3DSA:3.40.50.1820 3127 3473 3.4E-98 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_06395 da635be6dd9604a7529c71bbda853605 3477 Gene3D G3DSA:3.40.50.12780 2593 3010 2.4E-109 T 14-10-2018 MB46_06395 da635be6dd9604a7529c71bbda853605 3477 Gene3D G3DSA:3.40.50.12780 1520 1912 3.1E-105 T 14-10-2018 MB46_06395 da635be6dd9604a7529c71bbda853605 3477 Gene3D G3DSA:3.40.50.12780 458 871 6.5E-118 T 14-10-2018 MB46_06395 da635be6dd9604a7529c71bbda853605 3477 SMART SM00824 Thioesterase 3229 3468 3.5E-4 T 14-10-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 MB46_06395 da635be6dd9604a7529c71bbda853605 3477 SUPERFAMILY SSF56801 456 994 2.62E-131 T 14-10-2018 MB46_06395 da635be6dd9604a7529c71bbda853605 3477 SUPERFAMILY SSF52777 2326 2573 1.45E-47 T 14-10-2018 MB46_06395 da635be6dd9604a7529c71bbda853605 3477 Gene3D G3DSA:3.30.300.30 3011 3126 5.8E-32 T 14-10-2018 MB46_06395 da635be6dd9604a7529c71bbda853605 3477 Pfam PF00501 AMP-binding enzyme 2605 3016 8.1E-79 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 MB46_06395 da635be6dd9604a7529c71bbda853605 3477 Pfam PF00501 AMP-binding enzyme 1532 1918 1.3E-75 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 MB46_06395 da635be6dd9604a7529c71bbda853605 3477 Pfam PF00501 AMP-binding enzyme 470 877 5.3E-82 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 MB46_06395 da635be6dd9604a7529c71bbda853605 3477 ProSitePatterns PS00455 Putative AMP-binding domain signature. 619 630 - T 14-10-2018 IPR020845 AMP-binding, conserved site MB46_06395 da635be6dd9604a7529c71bbda853605 3477 SUPERFAMILY SSF52777 207 434 3.11E-18 T 14-10-2018 MB46_06395 da635be6dd9604a7529c71bbda853605 3477 SUPERFAMILY SSF47336 3129 3198 1.83E-16 T 14-10-2018 IPR036736 ACP-like superfamily MB46_06395 da635be6dd9604a7529c71bbda853605 3477 Gene3D G3DSA:3.30.559.30 1243 1498 4.9E-144 T 14-10-2018 MB46_06395 da635be6dd9604a7529c71bbda853605 3477 Gene3D G3DSA:3.30.559.30 2323 2572 2.8E-130 T 14-10-2018 MB46_06395 da635be6dd9604a7529c71bbda853605 3477 Gene3D G3DSA:3.30.559.10 1066 1438 4.9E-144 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 MB46_06395 da635be6dd9604a7529c71bbda853605 3477 Gene3D G3DSA:3.30.300.30 872 971 6.4E-31 T 14-10-2018 MB46_06395 da635be6dd9604a7529c71bbda853605 3477 Gene3D G3DSA:3.30.300.30 1913 2007 2.5E-26 T 14-10-2018 MB46_06395 da635be6dd9604a7529c71bbda853605 3477 Gene3D G3DSA:3.30.559.10 19 221 1.8E-46 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 MB46_09350 b735724138c683f9ea4dc714e82f3c38 286 Gene3D G3DSA:3.40.630.120 133 285 7.4E-49 T 14-10-2018 MB46_15635 361e2dbf4dedc532d2e340b319e87b6d 258 Gene3D G3DSA:3.20.20.190 14 255 3.6E-68 T 14-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 MB46_15635 361e2dbf4dedc532d2e340b319e87b6d 258 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 19 245 2.3E-38 T 14-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 MB46_15635 361e2dbf4dedc532d2e340b319e87b6d 258 SUPERFAMILY SSF51695 13 251 7.85E-61 T 14-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 MB46_00050 40d2a01e5779fa89e01bd02b331eb928 530 Gene3D G3DSA:1.10.3720.10 287 524 3.1E-68 T 14-10-2018 IPR035906 MetI-like superfamily MB46_00050 40d2a01e5779fa89e01bd02b331eb928 530 Gene3D G3DSA:1.20.58.370 12 107 1.7E-6 T 14-10-2018 IPR035277 MalF, N-terminal MB46_00050 40d2a01e5779fa89e01bd02b331eb928 530 Gene3D G3DSA:3.10.650.10 131 284 1.4E-6 T 14-10-2018 MB46_00050 40d2a01e5779fa89e01bd02b331eb928 530 Gene3D G3DSA:2.40.430.10 133 227 1.4E-6 T 14-10-2018 MB46_00050 40d2a01e5779fa89e01bd02b331eb928 530 SUPERFAMILY SSF161098 276 516 8.11E-63 T 14-10-2018 IPR035906 MetI-like superfamily MB46_00050 40d2a01e5779fa89e01bd02b331eb928 530 Pfam PF16296 N-terminal of TM subunit in PBP-dependent ABC transporters 86 162 1.6E-26 T 14-10-2018 IPR032550 PBP-dependent ABC transporters TM subunit, N-terminal MB46_00050 40d2a01e5779fa89e01bd02b331eb928 530 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 313 518 3.8E-23 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_00050 40d2a01e5779fa89e01bd02b331eb928 530 SUPERFAMILY SSF160964 26 275 4.45E-60 T 14-10-2018 MB46_06040 00b19a128ed8056cbf18c26d1195d16c 425 Gene3D G3DSA:3.30.70.2520 292 385 1.5E-35 T 14-10-2018 MB46_06040 00b19a128ed8056cbf18c26d1195d16c 425 PIRSF PIRSF000136 275 424 3.7E-8 T 14-10-2018 IPR010031 L-gulonolactone/D-arabinono-1,4-lactone oxidase GO:0016899|GO:0055114 MB46_06040 00b19a128ed8056cbf18c26d1195d16c 425 PIRSF PIRSF000136 3 217 3.4E-42 T 14-10-2018 IPR010031 L-gulonolactone/D-arabinono-1,4-lactone oxidase GO:0016899|GO:0055114 MB46_06040 00b19a128ed8056cbf18c26d1195d16c 425 Gene3D G3DSA:3.30.465.10 73 290 5.7E-82 T 14-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 MB46_06040 00b19a128ed8056cbf18c26d1195d16c 425 SUPERFAMILY SSF56176 9 178 3.27E-36 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 MB46_06040 00b19a128ed8056cbf18c26d1195d16c 425 Pfam PF01565 FAD binding domain 24 151 2.5E-22 T 14-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 MB46_06040 00b19a128ed8056cbf18c26d1195d16c 425 Gene3D G3DSA:3.30.70.2530 183 273 5.7E-82 T 14-10-2018 MB46_06040 00b19a128ed8056cbf18c26d1195d16c 425 Pfam PF04030 D-arabinono-1,4-lactone oxidase 293 421 6.9E-20 T 14-10-2018 IPR007173 D-arabinono-1,4-lactone oxidase GO:0003885|GO:0016020|GO:0055114 MB46_06040 00b19a128ed8056cbf18c26d1195d16c 425 Gene3D G3DSA:3.30.43.10 6 68 2.0E-21 T 14-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 MB46_06040 00b19a128ed8056cbf18c26d1195d16c 425 Gene3D G3DSA:1.10.45.10 386 423 8.9E-9 T 14-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 MB46_16040 f599630a9e182249ac314692c137029d 318 SUPERFAMILY SSF51905 6 311 1.12E-54 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_16040 f599630a9e182249ac314692c137029d 318 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 13 302 1.8E-50 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MB46_16040 f599630a9e182249ac314692c137029d 318 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 113 131 1.2E-37 T 14-10-2018 MB46_16040 f599630a9e182249ac314692c137029d 318 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 266 288 1.2E-37 T 14-10-2018 MB46_16040 f599630a9e182249ac314692c137029d 318 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 14 33 1.2E-37 T 14-10-2018 MB46_16040 f599630a9e182249ac314692c137029d 318 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 155 173 1.2E-37 T 14-10-2018 MB46_16040 f599630a9e182249ac314692c137029d 318 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 239 255 1.2E-37 T 14-10-2018 MB46_16040 f599630a9e182249ac314692c137029d 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 203 219 1.6E-76 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MB46_16040 f599630a9e182249ac314692c137029d 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 276 294 1.6E-76 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MB46_16040 f599630a9e182249ac314692c137029d 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 68 78 1.6E-76 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MB46_16040 f599630a9e182249ac314692c137029d 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 241 262 1.6E-76 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MB46_16040 f599630a9e182249ac314692c137029d 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 47 62 1.6E-76 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MB46_16040 f599630a9e182249ac314692c137029d 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 151 175 1.6E-76 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MB46_16040 f599630a9e182249ac314692c137029d 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 136 148 1.6E-76 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MB46_16040 f599630a9e182249ac314692c137029d 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 13 35 1.6E-76 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MB46_16040 f599630a9e182249ac314692c137029d 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 114 122 1.6E-76 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MB46_16040 f599630a9e182249ac314692c137029d 318 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 143 163 - T 14-10-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 MB46_16040 f599630a9e182249ac314692c137029d 318 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 13 313 5.1E-121 T 14-10-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 MB46_16040 f599630a9e182249ac314692c137029d 318 Gene3D G3DSA:3.50.50.60 130 252 2.1E-117 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_16040 f599630a9e182249ac314692c137029d 318 Gene3D G3DSA:3.50.50.60 14 312 2.1E-117 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_13885 6cdf5a50908bfa9db203bbffa0752698 461 Gene3D G3DSA:3.40.50.1100 41 154 9.4E-117 T 14-10-2018 MB46_13885 6cdf5a50908bfa9db203bbffa0752698 461 Gene3D G3DSA:3.10.580.10 334 460 2.1E-15 T 14-10-2018 MB46_13885 6cdf5a50908bfa9db203bbffa0752698 461 SUPERFAMILY SSF54631 339 459 1.64E-13 T 14-10-2018 MB46_13885 6cdf5a50908bfa9db203bbffa0752698 461 SMART SM00116 345 398 0.0012 T 14-10-2018 IPR000644 CBS domain MB46_13885 6cdf5a50908bfa9db203bbffa0752698 461 SUPERFAMILY SSF53686 1 324 2.88E-92 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme MB46_13885 6cdf5a50908bfa9db203bbffa0752698 461 Gene3D G3DSA:3.40.50.1100 9 310 9.4E-117 T 14-10-2018 MB46_13885 6cdf5a50908bfa9db203bbffa0752698 461 Pfam PF00571 CBS domain 344 394 2.0E-5 T 14-10-2018 IPR000644 CBS domain MB46_13885 6cdf5a50908bfa9db203bbffa0752698 461 TIGRFAM TIGR01137 cysta_beta: cystathionine beta-synthase 5 459 2.1E-177 T 14-10-2018 IPR005857 Cystathionine beta-synthase GO:0004122|GO:0005737|GO:0019343 KEGG: 00260+4.2.1.22|KEGG: 00270+4.2.1.22|MetaCyc: PWY-801 MB46_13885 6cdf5a50908bfa9db203bbffa0752698 461 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 9 303 1.6E-66 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme MB46_13885 6cdf5a50908bfa9db203bbffa0752698 461 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 33 51 - T 14-10-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 MB46_13960 b8979234d4ff571e4be30ca325923918 495 SUPERFAMILY SSF53067 253 482 5.83E-57 T 14-10-2018 MB46_13960 b8979234d4ff571e4be30ca325923918 495 PIRSF PIRSF000538 1 489 3.9E-124 T 14-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 MB46_13960 b8979234d4ff571e4be30ca325923918 495 Gene3D G3DSA:3.30.420.40 2 238 3.0E-65 T 14-10-2018 MB46_13960 b8979234d4ff571e4be30ca325923918 495 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 259 439 9.0E-36 T 14-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 MB46_13960 b8979234d4ff571e4be30ca325923918 495 Gene3D G3DSA:3.30.420.40 240 493 5.7E-65 T 14-10-2018 MB46_13960 b8979234d4ff571e4be30ca325923918 495 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 3 241 4.8E-46 T 14-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 MB46_13960 b8979234d4ff571e4be30ca325923918 495 SUPERFAMILY SSF53067 4 250 2.75E-52 T 14-10-2018 MB46_13960 b8979234d4ff571e4be30ca325923918 495 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 352 372 - T 14-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 MB46_07565 f9421f1fe56ee55f991b16fb19d5cabb 480 PIRSF PIRSF006060 1 475 8.9E-51 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 MB46_07565 f9421f1fe56ee55f991b16fb19d5cabb 480 Gene3D G3DSA:1.20.1740.10 7 453 8.4E-55 T 14-10-2018 MB46_07565 f9421f1fe56ee55f991b16fb19d5cabb 480 Pfam PF13520 Amino acid permease 13 420 1.5E-60 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 MB46_07565 f9421f1fe56ee55f991b16fb19d5cabb 480 TIGRFAM TIGR00905 2A0302: transporter, basic amino acid/polyamine antiporter (APA) family 5 480 2.6E-140 T 14-10-2018 IPR004754 Amino acid antiporter GO:0006865|GO:0016021 MB46_08235 d847dc5cf44952fd1ca2767e43d65a58 485 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 26 475 1.0E-140 T 14-10-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MB46_08235 d847dc5cf44952fd1ca2767e43d65a58 485 Pfam PF02875 Mur ligase family, glutamate ligase domain 339 423 4.9E-22 T 14-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 MB46_08235 d847dc5cf44952fd1ca2767e43d65a58 485 Pfam PF01225 Mur ligase family, catalytic domain 26 122 1.9E-23 T 14-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 MB46_08235 d847dc5cf44952fd1ca2767e43d65a58 485 SUPERFAMILY SSF51984 25 110 8.63E-24 T 14-10-2018 MB46_08235 d847dc5cf44952fd1ca2767e43d65a58 485 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 23 481 37.64 T 14-10-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MB46_08235 d847dc5cf44952fd1ca2767e43d65a58 485 Gene3D G3DSA:3.40.50.720 25 111 6.6E-29 T 14-10-2018 MB46_08235 d847dc5cf44952fd1ca2767e43d65a58 485 Pfam PF08245 Mur ligase middle domain 128 317 2.2E-27 T 14-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 MB46_08235 d847dc5cf44952fd1ca2767e43d65a58 485 Gene3D G3DSA:3.90.190.20 335 484 2.1E-50 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MB46_08235 d847dc5cf44952fd1ca2767e43d65a58 485 SUPERFAMILY SSF53623 109 335 1.49E-57 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 MB46_08235 d847dc5cf44952fd1ca2767e43d65a58 485 Gene3D G3DSA:3.40.1190.10 112 334 5.8E-68 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 MB46_08235 d847dc5cf44952fd1ca2767e43d65a58 485 SUPERFAMILY SSF53244 336 478 5.34E-41 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MB46_03140 5b431be7dc102ee1a48c7607f281a19e 319 Pfam PF00294 pfkB family carbohydrate kinase 15 304 8.0E-37 T 14-10-2018 IPR011611 Carbohydrate kinase PfkB MB46_03140 5b431be7dc102ee1a48c7607f281a19e 319 SUPERFAMILY SSF53613 6 311 2.03E-53 T 14-10-2018 IPR029056 Ribokinase-like MB46_03140 5b431be7dc102ee1a48c7607f281a19e 319 PIRSF PIRSF000535 2 318 6.8E-61 T 14-10-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 MB46_03140 5b431be7dc102ee1a48c7607f281a19e 319 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 257 270 - T 14-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 MB46_03140 5b431be7dc102ee1a48c7607f281a19e 319 Gene3D G3DSA:3.40.1190.20 3 318 4.5E-83 T 14-10-2018 IPR029056 Ribokinase-like MB46_03140 5b431be7dc102ee1a48c7607f281a19e 319 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 5 307 3.0E-70 T 14-10-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 MB46_07955 6e6a1388433ad039db6ae8bbd064b761 891 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 349 484 4.3E-38 T 14-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain MB46_07955 6e6a1388433ad039db6ae8bbd064b761 891 SUPERFAMILY SSF56059 671 875 1.06E-22 T 14-10-2018 MB46_07955 6e6a1388433ad039db6ae8bbd064b761 891 Pfam PF13380 CoA binding domain 205 330 1.7E-17 T 14-10-2018 IPR003781 CoA-binding GO:0048037 MB46_07955 6e6a1388433ad039db6ae8bbd064b761 891 SUPERFAMILY SSF51735 196 332 9.86E-28 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_07955 6e6a1388433ad039db6ae8bbd064b761 891 Gene3D G3DSA:3.30.470.20 668 875 9.2E-55 T 14-10-2018 MB46_07955 6e6a1388433ad039db6ae8bbd064b761 891 Gene3D G3DSA:3.40.50.261 529 634 1.4E-8 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MB46_07955 6e6a1388433ad039db6ae8bbd064b761 891 Gene3D G3DSA:3.40.50.261 328 488 1.1E-42 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MB46_07955 6e6a1388433ad039db6ae8bbd064b761 891 SUPERFAMILY SSF52210 491 631 6.54E-16 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MB46_07955 6e6a1388433ad039db6ae8bbd064b761 891 Gene3D G3DSA:3.40.50.720 199 325 6.5E-37 T 14-10-2018 MB46_07955 6e6a1388433ad039db6ae8bbd064b761 891 SUPERFAMILY SSF52210 327 487 2.88E-29 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MB46_07955 6e6a1388433ad039db6ae8bbd064b761 891 Gene3D G3DSA:3.30.1490.20 686 759 9.2E-55 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 MB46_07955 6e6a1388433ad039db6ae8bbd064b761 891 Pfam PF13549 ATP-grasp domain 667 875 2.2E-49 T 14-10-2018 MB46_07955 6e6a1388433ad039db6ae8bbd064b761 891 Gene3D G3DSA:3.40.50.261 489 528 6.8E-6 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MB46_07955 6e6a1388433ad039db6ae8bbd064b761 891 SMART SM00881 201 296 5.5E-29 T 14-10-2018 IPR003781 CoA-binding GO:0048037 MB46_07955 6e6a1388433ad039db6ae8bbd064b761 891 Gene3D G3DSA:3.40.630.30 17 198 2.0E-47 T 14-10-2018 MB46_07955 6e6a1388433ad039db6ae8bbd064b761 891 Pfam PF13420 Acetyltransferase (GNAT) domain 28 167 2.9E-11 T 14-10-2018 MB46_07955 6e6a1388433ad039db6ae8bbd064b761 891 SUPERFAMILY SSF55729 28 166 1.3E-23 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase MB46_13830 cec44c2489cbb5732e3dd942f10af131 220 Gene3D G3DSA:2.40.33.20 11 209 1.9E-60 T 14-10-2018 MB46_13830 cec44c2489cbb5732e3dd942f10af131 220 Pfam PF03473 MOSC domain 55 166 3.2E-23 T 14-10-2018 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 MB46_13830 cec44c2489cbb5732e3dd942f10af131 220 SUPERFAMILY SSF50800 19 218 5.75E-56 T 14-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily MB46_14950 3acd01306f2ed15d2fedfffd2bc4b069 264 Pfam PF13242 HAD-hyrolase-like 187 260 7.7E-23 T 14-10-2018 MB46_14950 3acd01306f2ed15d2fedfffd2bc4b069 264 Gene3D G3DSA:3.40.50.1000 92 187 1.6E-78 T 14-10-2018 IPR023214 HAD superfamily MB46_14950 3acd01306f2ed15d2fedfffd2bc4b069 264 Gene3D G3DSA:3.40.50.1000 15 250 1.6E-78 T 14-10-2018 IPR023214 HAD superfamily MB46_14950 3acd01306f2ed15d2fedfffd2bc4b069 264 Pfam PF13344 Haloacid dehalogenase-like hydrolase 15 114 4.0E-26 T 14-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA MB46_14950 3acd01306f2ed15d2fedfffd2bc4b069 264 SUPERFAMILY SSF56784 12 261 2.03E-69 T 14-10-2018 IPR036412 HAD-like superfamily MB46_14950 3acd01306f2ed15d2fedfffd2bc4b069 264 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 16 236 3.8E-48 T 14-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA MB46_14950 3acd01306f2ed15d2fedfffd2bc4b069 264 PIRSF PIRSF000915 2 264 2.1E-55 T 14-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA MB46_00970 990da6c6d73267645fd3ab39b944f1b1 126 SUPERFAMILY SSF50249 3 64 5.39E-12 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold MB46_00970 990da6c6d73267645fd3ab39b944f1b1 126 Gene3D G3DSA:2.40.50.140 3 64 3.3E-14 T 14-10-2018 MB46_00970 990da6c6d73267645fd3ab39b944f1b1 126 SMART SM00357 3 65 1.1E-5 T 14-10-2018 IPR011129 Cold shock domain GO:0003676 MB46_00970 990da6c6d73267645fd3ab39b944f1b1 126 Pfam PF00313 'Cold-shock' DNA-binding domain 4 60 8.5E-11 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MB46_00970 990da6c6d73267645fd3ab39b944f1b1 126 PRINTS PR00050 Cold shock protein signature 4 19 4.3E-8 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MB46_00970 990da6c6d73267645fd3ab39b944f1b1 126 PRINTS PR00050 Cold shock protein signature 24 33 4.3E-8 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MB46_00970 990da6c6d73267645fd3ab39b944f1b1 126 PRINTS PR00050 Cold shock protein signature 38 56 4.3E-8 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MB46_08285 6f68336ceed5025d221ffedebd54ed87 143 TIGRFAM TIGR00242 TIGR00242: division/cell wall cluster transcriptional repressor MraZ 1 135 5.1E-36 T 14-10-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 MB46_08285 6f68336ceed5025d221ffedebd54ed87 143 ProDom PD006745 MRAZ YABB DIVISION CELL 3D-STRUCTURE UNCHARACTERIZED BCR SIMILAR PROTEIN 1 129 1.0E-55 T 14-10-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 MB46_08285 6f68336ceed5025d221ffedebd54ed87 143 Pfam PF02381 MraZ protein, putative antitoxin-like 1 68 1.5E-18 T 14-10-2018 IPR020603 MraZ domain MB46_08285 6f68336ceed5025d221ffedebd54ed87 143 Pfam PF02381 MraZ protein, putative antitoxin-like 72 135 3.5E-17 T 14-10-2018 IPR020603 MraZ domain MB46_08285 6f68336ceed5025d221ffedebd54ed87 143 Gene3D G3DSA:2.40.330.20 1 138 6.1E-44 T 14-10-2018 IPR038619 MraZ superfamily MB46_08285 6f68336ceed5025d221ffedebd54ed87 143 Hamap MF_01008 Transcriptional regulator MraZ [mraZ]. 1 143 47.788 T 14-10-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 MB46_08285 6f68336ceed5025d221ffedebd54ed87 143 SUPERFAMILY SSF89447 2 135 1.78E-43 T 14-10-2018 IPR037914 SpoVT-AbrB domain superfamily MB46_03240 96105766da59aa355189bea56cf1052d 329 SUPERFAMILY SSF55729 3 101 5.04E-9 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase MB46_03240 96105766da59aa355189bea56cf1052d 329 Gene3D G3DSA:3.40.630.30 6 236 8.0E-10 T 14-10-2018 MB46_15685 88f82faf18a44b3fe042e9d2623ef4c4 267 Gene3D G3DSA:3.40.190.10 74 174 1.2E-23 T 14-10-2018 MB46_15685 88f82faf18a44b3fe042e9d2623ef4c4 267 Gene3D G3DSA:3.40.190.10 20 179 1.2E-23 T 14-10-2018 MB46_15685 88f82faf18a44b3fe042e9d2623ef4c4 267 SUPERFAMILY SSF53850 5 187 7.76E-23 T 14-10-2018 MB46_15685 88f82faf18a44b3fe042e9d2623ef4c4 267 Pfam PF03466 LysR substrate binding domain 7 184 6.8E-25 T 14-10-2018 IPR005119 LysR, substrate-binding MB46_17580 fdd22138760be11dcfb7507dabbf00e1 335 SMART SM00354 3 73 4.5E-24 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MB46_17580 fdd22138760be11dcfb7507dabbf00e1 335 Pfam PF00356 Bacterial regulatory proteins, lacI family 5 50 1.9E-13 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MB46_17580 fdd22138760be11dcfb7507dabbf00e1 335 SUPERFAMILY SSF47413 2 61 1.31E-14 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MB46_17580 fdd22138760be11dcfb7507dabbf00e1 335 Gene3D G3DSA:1.10.260.40 1 61 1.9E-19 T 14-10-2018 MB46_17580 fdd22138760be11dcfb7507dabbf00e1 335 SUPERFAMILY SSF53822 61 330 2.75E-62 T 14-10-2018 IPR028082 Periplasmic binding protein-like I MB46_17580 fdd22138760be11dcfb7507dabbf00e1 335 Pfam PF13377 Periplasmic binding protein-like domain 171 333 6.6E-34 T 14-10-2018 MB46_17580 fdd22138760be11dcfb7507dabbf00e1 335 Gene3D G3DSA:3.40.50.2300 64 325 6.6E-72 T 14-10-2018 MB46_17580 fdd22138760be11dcfb7507dabbf00e1 335 Gene3D G3DSA:3.40.50.2300 162 330 6.6E-72 T 14-10-2018 MB46_07825 4c3d2c4654a1babcb686203529af33f4 234 Pfam PF00106 short chain dehydrogenase 11 173 4.1E-22 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_07825 4c3d2c4654a1babcb686203529af33f4 234 Gene3D G3DSA:3.40.50.720 9 226 6.6E-31 T 14-10-2018 MB46_07825 4c3d2c4654a1babcb686203529af33f4 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 1.8E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_07825 4c3d2c4654a1babcb686203529af33f4 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 1.8E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_07825 4c3d2c4654a1babcb686203529af33f4 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 1.8E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_07825 4c3d2c4654a1babcb686203529af33f4 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 1.8E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_07825 4c3d2c4654a1babcb686203529af33f4 234 SUPERFAMILY SSF51735 7 173 1.6E-31 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_07425 7a19086de4722cb1bdc2430393858fe0 765 Pfam PF01345 Domain of unknown function DUF11 154 248 5.3E-6 T 14-10-2018 IPR001434 Domain of unknown function DUF11 MB46_07425 7a19086de4722cb1bdc2430393858fe0 765 Pfam PF01345 Domain of unknown function DUF11 290 340 6.0E-9 T 14-10-2018 IPR001434 Domain of unknown function DUF11 MB46_07425 7a19086de4722cb1bdc2430393858fe0 765 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 157 198 6.7E-4 T 14-10-2018 IPR001434 Domain of unknown function DUF11 MB46_07425 7a19086de4722cb1bdc2430393858fe0 765 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 292 341 2.1E-10 T 14-10-2018 IPR001434 Domain of unknown function DUF11 MB46_07425 7a19086de4722cb1bdc2430393858fe0 765 Gene3D G3DSA:2.60.40.10 590 701 1.3E-12 T 14-10-2018 IPR013783 Immunoglobulin-like fold MB46_07425 7a19086de4722cb1bdc2430393858fe0 765 Pfam PF00746 LPXTG cell wall anchor motif 725 759 2.7E-5 T 14-10-2018 IPR019948 Gram-positive LPXTG cell wall anchor MB46_13405 8bd0fb2ec1100a42c5e5ca4933a6805d 279 ProSitePatterns PS00548 Ribosomal protein S3 signature. 168 202 - T 14-10-2018 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MB46_13405 8bd0fb2ec1100a42c5e5ca4933a6805d 279 Gene3D G3DSA:3.30.300.20 17 111 8.7E-28 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta MB46_13405 8bd0fb2ec1100a42c5e5ca4933a6805d 279 Pfam PF00189 Ribosomal protein S3, C-terminal domain 124 207 5.5E-34 T 14-10-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MB46_13405 8bd0fb2ec1100a42c5e5ca4933a6805d 279 Pfam PF07650 KH domain 51 114 1.5E-18 T 14-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MB46_13405 8bd0fb2ec1100a42c5e5ca4933a6805d 279 Gene3D G3DSA:3.30.1140.32 112 213 7.3E-38 T 14-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MB46_13405 8bd0fb2ec1100a42c5e5ca4933a6805d 279 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 215 1.1E-88 T 14-10-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 MB46_13405 8bd0fb2ec1100a42c5e5ca4933a6805d 279 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 211 37.175 T 14-10-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 MB46_13405 8bd0fb2ec1100a42c5e5ca4933a6805d 279 SUPERFAMILY SSF54821 111 211 4.84E-36 T 14-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MB46_13405 8bd0fb2ec1100a42c5e5ca4933a6805d 279 SUPERFAMILY SSF54814 2 110 4.97E-33 T 14-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 MB46_13405 8bd0fb2ec1100a42c5e5ca4933a6805d 279 SMART SM00322 64 129 1.9E-7 T 14-10-2018 IPR004087 K Homology domain GO:0003676 MB46_12885 c89828d79a2f9267906fee4b4b1a34c3 306 Gene3D G3DSA:1.10.260.40 27 99 4.9E-6 T 14-10-2018 MB46_12885 c89828d79a2f9267906fee4b4b1a34c3 306 Pfam PF13560 Helix-turn-helix domain 10 85 1.2E-12 T 14-10-2018 MB46_12885 c89828d79a2f9267906fee4b4b1a34c3 306 SMART SM00530 6 82 1.3E-6 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MB46_12885 c89828d79a2f9267906fee4b4b1a34c3 306 Gene3D G3DSA:3.30.450.180 110 278 1.3E-13 T 14-10-2018 MB46_12885 c89828d79a2f9267906fee4b4b1a34c3 306 SUPERFAMILY SSF47413 31 77 1.16E-6 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MB46_16760 6b45009949eb86f3537d18f2368e853d 597 SUPERFAMILY SSF52540 343 581 1.55E-78 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_16760 6b45009949eb86f3537d18f2368e853d 597 ProSitePatterns PS00211 ABC transporters family signature. 486 500 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_16760 6b45009949eb86f3537d18f2368e853d 597 SMART SM00382 374 546 2.0E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_16760 6b45009949eb86f3537d18f2368e853d 597 SUPERFAMILY SSF90123 17 334 3.27E-64 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MB46_16760 6b45009949eb86f3537d18f2368e853d 597 Pfam PF00005 ABC transporter 365 514 1.6E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_16760 6b45009949eb86f3537d18f2368e853d 597 Pfam PF00664 ABC transporter transmembrane region 32 300 1.4E-38 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 MB46_16760 6b45009949eb86f3537d18f2368e853d 597 Gene3D G3DSA:1.20.1560.10 2 334 5.2E-71 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MB46_16760 6b45009949eb86f3537d18f2368e853d 597 Gene3D G3DSA:3.40.50.300 342 594 1.8E-80 T 14-10-2018 MB46_12570 e106ece29996378b51987faf354f66d0 132 SUPERFAMILY SSF54593 1 119 1.69E-13 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MB46_12570 e106ece29996378b51987faf354f66d0 132 Gene3D G3DSA:3.10.180.10 1 130 1.6E-35 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MB46_14400 819249e424eb235e856f38b9779d7ce9 201 Gene3D G3DSA:1.10.10.60 2 52 3.0E-8 T 14-10-2018 MB46_14400 819249e424eb235e856f38b9779d7ce9 201 SUPERFAMILY SSF46689 4 72 2.99E-9 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MB46_14400 819249e424eb235e856f38b9779d7ce9 201 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 49 7.5E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MB46_14400 819249e424eb235e856f38b9779d7ce9 201 Gene3D G3DSA:1.10.357.10 53 191 5.2E-5 T 14-10-2018 MB46_12825 90e8426838ce3b325243a2f4142d22df 567 SUPERFAMILY SSF53067 6 280 5.44E-41 T 14-10-2018 MB46_12825 90e8426838ce3b325243a2f4142d22df 567 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 290 487 3.2E-40 T 14-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 MB46_12825 90e8426838ce3b325243a2f4142d22df 567 Gene3D G3DSA:3.30.420.40 283 547 4.3E-74 T 14-10-2018 MB46_12825 90e8426838ce3b325243a2f4142d22df 567 SUPERFAMILY SSF53067 283 532 7.77E-54 T 14-10-2018 MB46_12825 90e8426838ce3b325243a2f4142d22df 567 Gene3D G3DSA:3.30.420.40 1 281 8.8E-69 T 14-10-2018 MB46_12825 90e8426838ce3b325243a2f4142d22df 567 PIRSF PIRSF000538 4 532 1.3E-59 T 14-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 MB46_12825 90e8426838ce3b325243a2f4142d22df 567 TIGRFAM TIGR01234 L-ribulokinase: ribulokinase 6 536 3.4E-237 T 14-10-2018 IPR005929 Ribulokinase GO:0005524|GO:0008741|GO:0019569 KEGG: 00040+2.7.1.16 MB46_12825 90e8426838ce3b325243a2f4142d22df 567 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 6 277 8.2E-14 T 14-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 MB46_12825 90e8426838ce3b325243a2f4142d22df 567 Hamap MF_00520 Ribulokinase [araB]. 4 544 46.62 T 14-10-2018 IPR005929 Ribulokinase GO:0005524|GO:0008741|GO:0019569 KEGG: 00040+2.7.1.16 MB46_06175 030fc874877312750984a03a2e1ef511 465 Gene3D G3DSA:1.20.1250.20 4 198 7.0E-26 T 14-10-2018 MB46_06175 030fc874877312750984a03a2e1ef511 465 Gene3D G3DSA:1.20.1250.20 199 454 4.1E-22 T 14-10-2018 MB46_06175 030fc874877312750984a03a2e1ef511 465 SUPERFAMILY SSF103473 201 453 2.35E-24 T 14-10-2018 IPR036259 MFS transporter superfamily MB46_06175 030fc874877312750984a03a2e1ef511 465 Pfam PF07690 Major Facilitator Superfamily 17 410 1.3E-31 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MB46_06175 030fc874877312750984a03a2e1ef511 465 SUPERFAMILY SSF103473 3 189 4.45E-27 T 14-10-2018 IPR036259 MFS transporter superfamily MB46_00775 f7bf674873ab67b820bd6ebf763e4d49 618 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 472 592 2.5E-40 T 14-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 MB46_00775 f7bf674873ab67b820bd6ebf763e4d49 618 Gene3D G3DSA:2.70.70.10 462 616 1.2E-51 T 14-10-2018 IPR011055 Duplicated hybrid motif MB46_00775 f7bf674873ab67b820bd6ebf763e4d49 618 TIGRFAM TIGR01995 PTS-II-ABC-beta: PTS system, beta-glucoside-specific IIABC component 6 608 1.7E-214 T 14-10-2018 IPR011297 Phosphotransferase system, beta-glucoside-specific IIABC component GO:0005886|GO:0008982|GO:0009401 MB46_00775 f7bf674873ab67b820bd6ebf763e4d49 618 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 22 39 - T 14-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 MB46_00775 f7bf674873ab67b820bd6ebf763e4d49 618 Gene3D G3DSA:3.30.1360.60 2 79 7.7E-26 T 14-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 MB46_00775 f7bf674873ab67b820bd6ebf763e4d49 618 SUPERFAMILY SSF55604 9 82 2.88E-20 T 14-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 MB46_00775 f7bf674873ab67b820bd6ebf763e4d49 618 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 534 546 - T 14-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 MB46_00775 f7bf674873ab67b820bd6ebf763e4d49 618 Pfam PF00367 phosphotransferase system, EIIB 12 44 9.0E-15 T 14-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 MB46_00775 f7bf674873ab67b820bd6ebf763e4d49 618 Pfam PF02378 Phosphotransferase system, EIIC 111 383 2.7E-29 T 14-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 MB46_00775 f7bf674873ab67b820bd6ebf763e4d49 618 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 471 595 4.3E-47 T 14-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 MB46_00775 f7bf674873ab67b820bd6ebf763e4d49 618 SUPERFAMILY SSF51261 466 609 1.08E-48 T 14-10-2018 IPR011055 Duplicated hybrid motif MB46_16130 2250aae83845e24c961a5156886460ce 881 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 55 497 5.2E-146 T 14-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MB46_16130 2250aae83845e24c961a5156886460ce 881 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 739 784 1.7E-11 T 14-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 MB46_16130 2250aae83845e24c961a5156886460ce 881 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 685 733 1.8E-10 T 14-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 MB46_16130 2250aae83845e24c961a5156886460ce 881 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 582 625 1.7E-7 T 14-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 MB46_16130 2250aae83845e24c961a5156886460ce 881 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 532 577 1.2E-12 T 14-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 MB46_16130 2250aae83845e24c961a5156886460ce 881 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 788 832 5.5E-6 T 14-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 MB46_16130 2250aae83845e24c961a5156886460ce 881 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 638 682 4.1E-12 T 14-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 MB46_16130 2250aae83845e24c961a5156886460ce 881 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 23 836 22.852 T 14-10-2018 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MB46_16130 2250aae83845e24c961a5156886460ce 881 Gene3D G3DSA:3.90.199.10 55 513 1.7E-191 T 14-10-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 MB46_16130 2250aae83845e24c961a5156886460ce 881 Gene3D G3DSA:1.10.268.10 396 484 1.7E-191 T 14-10-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily GO:0003677|GO:0003918|GO:0005524 Reactome: R-HSA-4615885 MB46_16130 2250aae83845e24c961a5156886460ce 881 Gene3D G3DSA:3.30.1360.40 263 359 1.7E-191 T 14-10-2018 MB46_16130 2250aae83845e24c961a5156886460ce 881 SMART SM00434 34 491 1.3E-261 T 14-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MB46_16130 2250aae83845e24c961a5156886460ce 881 SUPERFAMILY SSF56719 53 513 1.83E-163 T 14-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 MB46_16130 2250aae83845e24c961a5156886460ce 881 Gene3D G3DSA:2.120.10.90 528 836 4.2E-118 T 14-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal MB46_16130 2250aae83845e24c961a5156886460ce 881 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 32 834 0.0 T 14-10-2018 MB46_16130 2250aae83845e24c961a5156886460ce 881 SUPERFAMILY SSF101904 526 850 3.4E-101 T 14-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal MB46_02085 ed5fb27fb712821e957d38fb986756e9 164 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 90 159 1.2E-9 T 14-10-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 MB46_02085 ed5fb27fb712821e957d38fb986756e9 164 Hamap MF_00105 Transcription elongation factor GreA [greA]. 9 160 25.947 T 14-10-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 MB46_02085 ed5fb27fb712821e957d38fb986756e9 164 PIRSF PIRSF006092 8 162 9.8E-30 T 14-10-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 MB46_02085 ed5fb27fb712821e957d38fb986756e9 164 SUPERFAMILY SSF46557 11 83 1.16E-22 T 14-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 MB46_02085 ed5fb27fb712821e957d38fb986756e9 164 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 24 55 - T 14-10-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 MB46_02085 ed5fb27fb712821e957d38fb986756e9 164 Gene3D G3DSA:1.10.287.180 10 81 1.7E-23 T 14-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 MB46_02085 ed5fb27fb712821e957d38fb986756e9 164 SUPERFAMILY SSF54534 86 159 1.57E-7 T 14-10-2018 MB46_02085 ed5fb27fb712821e957d38fb986756e9 164 Pfam PF03449 Transcription elongation factor, N-terminal 12 81 2.1E-26 T 14-10-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 MB46_04755 8fffef0e7be57a0772c634791d61f28a 354 SUPERFAMILY SSF52418 86 351 2.49E-78 T 14-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 MB46_04755 8fffef0e7be57a0772c634791d61f28a 354 Pfam PF00591 Glycosyl transferase family, a/b domain 84 339 1.4E-80 T 14-10-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 MB46_04755 8fffef0e7be57a0772c634791d61f28a 354 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 19 348 5.4E-109 T 14-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 MB46_04755 8fffef0e7be57a0772c634791d61f28a 354 Gene3D G3DSA:3.40.1030.10 84 353 1.8E-95 T 14-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 MB46_04755 8fffef0e7be57a0772c634791d61f28a 354 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 16 349 33.958 T 14-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 MB46_04755 8fffef0e7be57a0772c634791d61f28a 354 Pfam PF02885 Glycosyl transferase family, helical bundle domain 17 76 4.0E-20 T 14-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 MB46_04755 8fffef0e7be57a0772c634791d61f28a 354 SUPERFAMILY SSF47648 14 80 1.7E-19 T 14-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 MB46_04755 8fffef0e7be57a0772c634791d61f28a 354 Gene3D G3DSA:1.20.970.10 12 77 4.5E-29 T 14-10-2018 MB46_18730 5dd0ac60a708f258d0ce841657596028 147 SMART SM00347 33 132 4.5E-18 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MB46_18730 5dd0ac60a708f258d0ce841657596028 147 Pfam PF12802 MarR family 40 96 5.9E-12 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MB46_18730 5dd0ac60a708f258d0ce841657596028 147 SUPERFAMILY SSF46785 17 139 4.09E-25 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_18730 5dd0ac60a708f258d0ce841657596028 147 Gene3D G3DSA:1.10.10.10 15 146 4.7E-30 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_08415 f0891c401c059c2fa86eb4248819a33c 598 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 282 447 1.2E-22 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MB46_08415 f0891c401c059c2fa86eb4248819a33c 598 Pfam PF12806 Acetyl-CoA dehydrogenase C-terminal like 468 585 4.3E-22 T 14-10-2018 IPR025878 Acetyl-CoA dehydrogenase-like C-terminal domain MB46_08415 f0891c401c059c2fa86eb4248819a33c 598 SUPERFAMILY SSF47203 280 456 5.15E-40 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 MB46_08415 f0891c401c059c2fa86eb4248819a33c 598 Pfam PF12418 Acyl-CoA dehydrogenase N terminal 4 34 5.3E-6 T 14-10-2018 IPR020953 Acyl-CoA dehydrogenase, N-terminal, bacteria MB46_08415 f0891c401c059c2fa86eb4248819a33c 598 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 40 158 1.5E-14 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MB46_08415 f0891c401c059c2fa86eb4248819a33c 598 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 163 272 8.4E-19 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MB46_08415 f0891c401c059c2fa86eb4248819a33c 598 Gene3D G3DSA:2.40.110.10 161 287 5.0E-31 T 14-10-2018 MB46_08415 f0891c401c059c2fa86eb4248819a33c 598 SUPERFAMILY SSF56645 36 292 1.83E-62 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 MB46_08415 f0891c401c059c2fa86eb4248819a33c 598 Gene3D G3DSA:1.20.140.10 288 452 1.2E-40 T 14-10-2018 MB46_08415 f0891c401c059c2fa86eb4248819a33c 598 Gene3D G3DSA:1.10.540.10 35 160 4.2E-20 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 MB46_13180 a8e494f5de4c2b82eb7bb2050154685f 721 Gene3D G3DSA:2.70.98.60 10 284 7.6E-32 T 14-10-2018 IPR038417 Alpha-galactosidase, N-terminal domain superfamily KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 MB46_13180 a8e494f5de4c2b82eb7bb2050154685f 721 PIRSF PIRSF005536 12 709 5.3E-167 T 14-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 MB46_13180 a8e494f5de4c2b82eb7bb2050154685f 721 Pfam PF02065 Melibiase 265 603 1.1E-117 T 14-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 MB46_13180 a8e494f5de4c2b82eb7bb2050154685f 721 SUPERFAMILY SSF51445 298 630 1.19E-89 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily MB46_13180 a8e494f5de4c2b82eb7bb2050154685f 721 PRINTS PR00743 Glycosyl hydrolase family 36 signature 438 453 5.2E-38 T 14-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 MB46_13180 a8e494f5de4c2b82eb7bb2050154685f 721 PRINTS PR00743 Glycosyl hydrolase family 36 signature 330 345 5.2E-38 T 14-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 MB46_13180 a8e494f5de4c2b82eb7bb2050154685f 721 PRINTS PR00743 Glycosyl hydrolase family 36 signature 380 402 5.2E-38 T 14-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 MB46_13180 a8e494f5de4c2b82eb7bb2050154685f 721 PRINTS PR00743 Glycosyl hydrolase family 36 signature 513 529 5.2E-38 T 14-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 MB46_13180 a8e494f5de4c2b82eb7bb2050154685f 721 PRINTS PR00743 Glycosyl hydrolase family 36 signature 302 316 5.2E-38 T 14-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 MB46_13180 a8e494f5de4c2b82eb7bb2050154685f 721 PRINTS PR00743 Glycosyl hydrolase family 36 signature 488 504 5.2E-38 T 14-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 MB46_13180 a8e494f5de4c2b82eb7bb2050154685f 721 PRINTS PR00743 Glycosyl hydrolase family 36 signature 217 232 5.2E-38 T 14-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 MB46_13180 a8e494f5de4c2b82eb7bb2050154685f 721 Pfam PF16875 Glycosyl hydrolase family 36 N-terminal domain 29 259 3.3E-37 T 14-10-2018 IPR031704 Glycosyl hydrolase family 36, N-terminal KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 MB46_13180 a8e494f5de4c2b82eb7bb2050154685f 721 Gene3D G3DSA:3.20.20.70 285 600 3.1E-117 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MB46_13180 a8e494f5de4c2b82eb7bb2050154685f 721 ProSitePatterns PS00512 Alpha-galactosidase signature. 331 347 - T 14-10-2018 IPR000111 Glycoside hydrolase family 27/36, conserved site GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 MB46_15125 36b4d9c8d7107b9499742ecb21096e2b 331 SUPERFAMILY SSF52402 21 157 1.0E-29 T 14-10-2018 MB46_15125 36b4d9c8d7107b9499742ecb21096e2b 331 PRINTS PR01438 Universal stress protein signature 290 312 2.9E-14 T 14-10-2018 IPR006015 Universal stress protein A MB46_15125 36b4d9c8d7107b9499742ecb21096e2b 331 PRINTS PR01438 Universal stress protein signature 272 284 2.9E-14 T 14-10-2018 IPR006015 Universal stress protein A MB46_15125 36b4d9c8d7107b9499742ecb21096e2b 331 PRINTS PR01438 Universal stress protein signature 175 193 2.9E-14 T 14-10-2018 IPR006015 Universal stress protein A MB46_15125 36b4d9c8d7107b9499742ecb21096e2b 331 Pfam PF00582 Universal stress protein family 22 156 3.3E-20 T 14-10-2018 IPR006016 UspA MB46_15125 36b4d9c8d7107b9499742ecb21096e2b 331 Pfam PF00582 Universal stress protein family 176 312 9.1E-22 T 14-10-2018 IPR006016 UspA MB46_15125 36b4d9c8d7107b9499742ecb21096e2b 331 SUPERFAMILY SSF52402 178 319 8.29E-30 T 14-10-2018 MB46_15125 36b4d9c8d7107b9499742ecb21096e2b 331 Gene3D G3DSA:3.40.50.620 11 162 7.0E-38 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MB46_15125 36b4d9c8d7107b9499742ecb21096e2b 331 Gene3D G3DSA:3.40.50.620 168 320 6.2E-36 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MB46_19340 3b7ea4976816b7d111ba2591be87bb5c 414 Pfam PF01548 Transposase 27 181 4.2E-42 T 14-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 MB46_19340 3b7ea4976816b7d111ba2591be87bb5c 414 Pfam PF02371 Transposase IS116/IS110/IS902 family 290 371 7.7E-19 T 14-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 MB46_00810 cfab0798c3d9199d8353a78d919c7da9 468 ProSitePatterns PS00217 Sugar transport proteins signature 2. 136 161 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MB46_00810 cfab0798c3d9199d8353a78d919c7da9 468 Pfam PF00083 Sugar (and other) transporter 25 236 2.7E-23 T 14-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 MB46_00810 cfab0798c3d9199d8353a78d919c7da9 468 Pfam PF00083 Sugar (and other) transporter 246 445 2.8E-13 T 14-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 MB46_00810 cfab0798c3d9199d8353a78d919c7da9 468 ProSitePatterns PS00216 Sugar transport proteins signature 1. 309 326 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MB46_00810 cfab0798c3d9199d8353a78d919c7da9 468 SUPERFAMILY SSF103473 20 446 1.31E-61 T 14-10-2018 IPR036259 MFS transporter superfamily MB46_00810 cfab0798c3d9199d8353a78d919c7da9 468 Gene3D G3DSA:1.20.1250.20 22 452 1.9E-70 T 14-10-2018 MB46_16900 f0f5df8ecd859b7a96cd9c4051a84e3c 393 Pfam PF00665 Integrase core domain 133 254 6.4E-21 T 14-10-2018 IPR001584 Integrase, catalytic core GO:0015074 MB46_16900 f0f5df8ecd859b7a96cd9c4051a84e3c 393 SUPERFAMILY SSF46689 7 113 8.06E-14 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MB46_16900 f0f5df8ecd859b7a96cd9c4051a84e3c 393 Pfam PF13384 Homeodomain-like domain 7 47 2.7E-10 T 14-10-2018 MB46_16900 f0f5df8ecd859b7a96cd9c4051a84e3c 393 SUPERFAMILY SSF53098 128 295 3.54E-30 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily MB46_16900 f0f5df8ecd859b7a96cd9c4051a84e3c 393 Gene3D G3DSA:3.30.420.10 130 295 4.3E-23 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 MB46_07530 f0f5df8ecd859b7a96cd9c4051a84e3c 393 Pfam PF00665 Integrase core domain 133 254 6.4E-21 T 14-10-2018 IPR001584 Integrase, catalytic core GO:0015074 MB46_07530 f0f5df8ecd859b7a96cd9c4051a84e3c 393 SUPERFAMILY SSF46689 7 113 8.06E-14 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MB46_07530 f0f5df8ecd859b7a96cd9c4051a84e3c 393 Pfam PF13384 Homeodomain-like domain 7 47 2.7E-10 T 14-10-2018 MB46_07530 f0f5df8ecd859b7a96cd9c4051a84e3c 393 SUPERFAMILY SSF53098 128 295 3.54E-30 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily MB46_07530 f0f5df8ecd859b7a96cd9c4051a84e3c 393 Gene3D G3DSA:3.30.420.10 130 295 4.3E-23 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 MB46_09070 f0f5df8ecd859b7a96cd9c4051a84e3c 393 Pfam PF00665 Integrase core domain 133 254 6.4E-21 T 14-10-2018 IPR001584 Integrase, catalytic core GO:0015074 MB46_09070 f0f5df8ecd859b7a96cd9c4051a84e3c 393 SUPERFAMILY SSF46689 7 113 8.06E-14 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MB46_09070 f0f5df8ecd859b7a96cd9c4051a84e3c 393 Pfam PF13384 Homeodomain-like domain 7 47 2.7E-10 T 14-10-2018 MB46_09070 f0f5df8ecd859b7a96cd9c4051a84e3c 393 SUPERFAMILY SSF53098 128 295 3.54E-30 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily MB46_09070 f0f5df8ecd859b7a96cd9c4051a84e3c 393 Gene3D G3DSA:3.30.420.10 130 295 4.3E-23 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 MB46_05700 90377500a362003ca5803dea27d7b10f 247 Pfam PF00005 ABC transporter 20 168 1.1E-26 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_05700 90377500a362003ca5803dea27d7b10f 247 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_05700 90377500a362003ca5803dea27d7b10f 247 SUPERFAMILY SSF52540 4 229 7.55E-52 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_05700 90377500a362003ca5803dea27d7b10f 247 SMART SM00382 29 217 8.6E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_05700 90377500a362003ca5803dea27d7b10f 247 Gene3D G3DSA:3.40.50.300 1 242 5.1E-60 T 14-10-2018 MB46_19555 4f4ad2e6ab20538a0635f105aab23b11 394 Gene3D G3DSA:3.90.1720.10 242 389 1.3E-22 T 14-10-2018 MB46_19555 4f4ad2e6ab20538a0635f105aab23b11 394 SUPERFAMILY SSF54001 244 375 3.63E-13 T 14-10-2018 IPR038765 Papain-like cysteine peptidase superfamily MB46_19555 4f4ad2e6ab20538a0635f105aab23b11 394 Pfam PF05257 CHAP domain 264 361 1.4E-10 T 14-10-2018 IPR007921 CHAP domain MB46_11190 c1b73f1efa2ef186c4a3922d48dc1a09 350 Gene3D G3DSA:3.40.50.2300 175 300 2.6E-66 T 14-10-2018 MB46_11190 c1b73f1efa2ef186c4a3922d48dc1a09 350 SUPERFAMILY SSF47413 20 78 1.5E-14 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MB46_11190 c1b73f1efa2ef186c4a3922d48dc1a09 350 Pfam PF13377 Periplasmic binding protein-like domain 184 342 1.1E-35 T 14-10-2018 MB46_11190 c1b73f1efa2ef186c4a3922d48dc1a09 350 SMART SM00354 20 90 1.8E-24 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MB46_11190 c1b73f1efa2ef186c4a3922d48dc1a09 350 SUPERFAMILY SSF53822 80 347 5.98E-57 T 14-10-2018 IPR028082 Periplasmic binding protein-like I MB46_11190 c1b73f1efa2ef186c4a3922d48dc1a09 350 Gene3D G3DSA:3.40.50.2300 74 317 2.6E-66 T 14-10-2018 MB46_11190 c1b73f1efa2ef186c4a3922d48dc1a09 350 Gene3D G3DSA:1.10.260.40 14 73 2.8E-19 T 14-10-2018 MB46_11190 c1b73f1efa2ef186c4a3922d48dc1a09 350 Pfam PF00356 Bacterial regulatory proteins, lacI family 22 67 3.3E-15 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MB46_18825 cd66d91f12668378d3f0e7113916159b 473 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 278 386 4.9E-24 T 14-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MB46_18825 cd66d91f12668378d3f0e7113916159b 473 SUPERFAMILY SSF53738 14 189 2.71E-32 T 14-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MB46_18825 cd66d91f12668378d3f0e7113916159b 473 Gene3D G3DSA:3.40.120.10 267 387 4.5E-32 T 14-10-2018 MB46_18825 cd66d91f12668378d3f0e7113916159b 473 Gene3D G3DSA:3.30.310.50 390 473 6.0E-22 T 14-10-2018 MB46_18825 cd66d91f12668378d3f0e7113916159b 473 Gene3D G3DSA:3.40.120.10 184 266 7.3E-31 T 14-10-2018 MB46_18825 cd66d91f12668378d3f0e7113916159b 473 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 166 270 1.0E-23 T 14-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MB46_18825 cd66d91f12668378d3f0e7113916159b 473 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 14 141 1.1E-30 T 14-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MB46_18825 cd66d91f12668378d3f0e7113916159b 473 SUPERFAMILY SSF55957 388 473 5.76E-17 T 14-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MB46_18825 cd66d91f12668378d3f0e7113916159b 473 Gene3D G3DSA:3.40.120.10 11 151 3.3E-40 T 14-10-2018 MB46_18825 cd66d91f12668378d3f0e7113916159b 473 SUPERFAMILY SSF53738 165 271 2.39E-28 T 14-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MB46_18825 cd66d91f12668378d3f0e7113916159b 473 SUPERFAMILY SSF53738 290 385 6.28E-25 T 14-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MB46_18825 cd66d91f12668378d3f0e7113916159b 473 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 221 234 3.4E-23 T 14-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MB46_18825 cd66d91f12668378d3f0e7113916159b 473 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 250 265 3.4E-23 T 14-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MB46_18825 cd66d91f12668378d3f0e7113916159b 473 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 100 114 3.4E-23 T 14-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MB46_18825 cd66d91f12668378d3f0e7113916159b 473 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 182 201 3.4E-23 T 14-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MB46_18825 cd66d91f12668378d3f0e7113916159b 473 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 394 472 4.6E-10 T 14-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MB46_08140 c29512b0ae471aea2e075cecb33dc341 448 SUPERFAMILY SSF55931 107 446 4.9E-117 T 14-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 MB46_08140 c29512b0ae471aea2e075cecb33dc341 448 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 16 100 8.0E-26 T 14-10-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 MB46_08140 c29512b0ae471aea2e075cecb33dc341 448 Gene3D G3DSA:3.30.590.10 109 447 1.8E-120 T 14-10-2018 MB46_08140 c29512b0ae471aea2e075cecb33dc341 448 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 235 250 - T 14-10-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 MB46_08140 c29512b0ae471aea2e075cecb33dc341 448 SUPERFAMILY SSF54368 8 104 8.76E-29 T 14-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MB46_08140 c29512b0ae471aea2e075cecb33dc341 448 SMART SM01230 106 358 1.5E-124 T 14-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MB46_08140 c29512b0ae471aea2e075cecb33dc341 448 Pfam PF00120 Glutamine synthetase, catalytic domain 107 444 2.1E-123 T 14-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MB46_08140 c29512b0ae471aea2e075cecb33dc341 448 Gene3D G3DSA:3.10.20.70 2 108 8.4E-34 T 14-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MB46_14480 cc111ae46d660601d09565c22362919a 731 Pfam PF02897 Prolyl oligopeptidase, N-terminal beta-propeller domain 18 439 2.0E-82 T 14-10-2018 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 MB46_14480 cc111ae46d660601d09565c22362919a 731 Pfam PF00326 Prolyl oligopeptidase family 515 727 6.1E-62 T 14-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 MB46_14480 cc111ae46d660601d09565c22362919a 731 ProSitePatterns PS00708 Prolyl endopeptidase family serine active site. 555 585 - T 14-10-2018 IPR002471 Peptidase S9, serine active site GO:0004252|GO:0006508 MB46_14480 cc111ae46d660601d09565c22362919a 731 Gene3D G3DSA:3.40.50.1820 37 721 9.1E-240 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_14480 cc111ae46d660601d09565c22362919a 731 SUPERFAMILY SSF50993 15 457 2.01E-82 T 14-10-2018 MB46_14480 cc111ae46d660601d09565c22362919a 731 SUPERFAMILY SSF53474 466 704 7.29E-43 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_14480 cc111ae46d660601d09565c22362919a 731 Gene3D G3DSA:2.130.10.120 86 452 9.1E-240 T 14-10-2018 MB46_14480 cc111ae46d660601d09565c22362919a 731 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 548 567 1.1E-48 T 14-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 MB46_14480 cc111ae46d660601d09565c22362919a 731 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 578 598 1.1E-48 T 14-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 MB46_14480 cc111ae46d660601d09565c22362919a 731 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 655 677 1.1E-48 T 14-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 MB46_14480 cc111ae46d660601d09565c22362919a 731 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 494 512 1.1E-48 T 14-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 MB46_14480 cc111ae46d660601d09565c22362919a 731 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 520 544 1.1E-48 T 14-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 MB46_14480 cc111ae46d660601d09565c22362919a 731 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 637 652 1.1E-48 T 14-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 MB46_02760 d540347f3ce6caa3451ac53a4168b0f0 283 PIRSF PIRSF000477 15 283 3.7E-81 T 14-10-2018 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 MB46_02760 d540347f3ce6caa3451ac53a4168b0f0 283 Pfam PF01048 Phosphorylase superfamily 43 281 3.4E-36 T 14-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 MB46_02760 d540347f3ce6caa3451ac53a4168b0f0 283 SUPERFAMILY SSF53167 27 282 8.76E-73 T 14-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 MB46_02760 d540347f3ce6caa3451ac53a4168b0f0 283 TIGRFAM TIGR01698 PUNP: purine nucleotide phosphorylase 43 281 1.7E-99 T 14-10-2018 IPR011269 Putative purine nucleotide phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 MB46_02760 d540347f3ce6caa3451ac53a4168b0f0 283 TIGRFAM TIGR01697 PNPH-PUNA-XAPA: inosine/guanosine/xanthosine phosphorylase family 43 281 3.0E-69 T 14-10-2018 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 MB46_02760 d540347f3ce6caa3451ac53a4168b0f0 283 Gene3D G3DSA:3.40.50.1580 16 282 9.9E-84 T 14-10-2018 MB46_19780 77e99efd07f56942268b830edbbe035b 578 Gene3D G3DSA:3.30.420.10 188 399 5.0E-31 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 MB46_19780 77e99efd07f56942268b830edbbe035b 578 Pfam PF00665 Integrase core domain 191 325 1.6E-21 T 14-10-2018 IPR001584 Integrase, catalytic core GO:0015074 MB46_19780 77e99efd07f56942268b830edbbe035b 578 Pfam PF09299 Mu transposase, C-terminal 405 467 1.3E-11 T 14-10-2018 IPR015378 Transposase-like, Mu, C-terminal MB46_19780 77e99efd07f56942268b830edbbe035b 578 SUPERFAMILY SSF53098 184 380 3.54E-22 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily MB46_19780 77e99efd07f56942268b830edbbe035b 578 Pfam PF13518 Helix-turn-helix domain 43 93 6.0E-7 T 14-10-2018 MB46_03635 6c9498faa5931a5e67aa8a4c0914fdc0 404 PIRSF PIRSF006205 3 404 9.2E-134 T 14-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 MB46_03635 6c9498faa5931a5e67aa8a4c0914fdc0 404 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 4 397 7.4E-110 T 14-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 MB46_03635 6c9498faa5931a5e67aa8a4c0914fdc0 404 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 6 151 1.0E-26 T 14-10-2018 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 MB46_03635 6c9498faa5931a5e67aa8a4c0914fdc0 404 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 163 246 1.8E-36 T 14-10-2018 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 MB46_03635 6c9498faa5931a5e67aa8a4c0914fdc0 404 SUPERFAMILY SSF69055 309 400 5.89E-29 T 14-10-2018 IPR036169 DXP reductoisomerase, C-terminal domain superfamily KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 MB46_03635 6c9498faa5931a5e67aa8a4c0914fdc0 404 SUPERFAMILY SSF51735 4 167 1.31E-23 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_03635 6c9498faa5931a5e67aa8a4c0914fdc0 404 Gene3D G3DSA:1.10.1740.10 320 402 7.0E-28 T 14-10-2018 MB46_03635 6c9498faa5931a5e67aa8a4c0914fdc0 404 Gene3D G3DSA:3.40.50.720 1 167 4.0E-35 T 14-10-2018 MB46_03635 6c9498faa5931a5e67aa8a4c0914fdc0 404 Pfam PF13288 DXP reductoisomerase C-terminal domain 279 394 1.2E-37 T 14-10-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 MB46_03635 6c9498faa5931a5e67aa8a4c0914fdc0 404 SUPERFAMILY SSF55347 145 281 1.93E-53 T 14-10-2018 MB46_03635 6c9498faa5931a5e67aa8a4c0914fdc0 404 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 6 399 42.739 T 14-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 MB46_12985 287e50413bac8d4cc5b74a7e315edf3a 374 TIGRFAM TIGR01304 IMP_DH_rel_2: IMP dehydrogenase family protein 5 372 1.8E-171 T 14-10-2018 IPR005992 IMP dehydrogenase-related 2 GO:0016491|GO:0055114 MB46_12985 287e50413bac8d4cc5b74a7e315edf3a 374 SUPERFAMILY SSF51412 13 372 1.09E-64 T 14-10-2018 MB46_12985 287e50413bac8d4cc5b74a7e315edf3a 374 Gene3D G3DSA:3.20.20.70 16 373 1.6E-89 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MB46_12985 287e50413bac8d4cc5b74a7e315edf3a 374 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 17 303 9.8E-40 T 14-10-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 MB46_12985 287e50413bac8d4cc5b74a7e315edf3a 374 SMART SM01240 15 374 3.9E-19 T 14-10-2018 MB46_07335 5e664dcefc27daebdb1ea013593624a0 110 Pfam PF12840 Helix-turn-helix domain 20 73 3.6E-8 T 14-10-2018 MB46_07335 5e664dcefc27daebdb1ea013593624a0 110 SUPERFAMILY SSF46785 7 96 1.55E-11 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_07335 5e664dcefc27daebdb1ea013593624a0 110 Gene3D G3DSA:1.10.10.10 2 97 8.2E-11 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_07335 5e664dcefc27daebdb1ea013593624a0 110 SMART SM00418 20 98 1.4E-9 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MB46_17825 d272292620d8e0d546e112fbb048306f 341 Gene3D G3DSA:1.10.260.40 1 57 8.7E-20 T 14-10-2018 MB46_17825 d272292620d8e0d546e112fbb048306f 341 Gene3D G3DSA:3.40.50.2300 160 293 5.3E-45 T 14-10-2018 MB46_17825 d272292620d8e0d546e112fbb048306f 341 SUPERFAMILY SSF53822 58 320 4.71E-33 T 14-10-2018 IPR028082 Periplasmic binding protein-like I MB46_17825 d272292620d8e0d546e112fbb048306f 341 Gene3D G3DSA:3.40.50.2300 80 313 5.3E-45 T 14-10-2018 MB46_17825 d272292620d8e0d546e112fbb048306f 341 SUPERFAMILY SSF47413 2 59 6.75E-16 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MB46_17825 d272292620d8e0d546e112fbb048306f 341 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 1.3E-17 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MB46_17825 d272292620d8e0d546e112fbb048306f 341 SMART SM00354 1 71 7.7E-27 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MB46_17825 d272292620d8e0d546e112fbb048306f 341 Pfam PF13377 Periplasmic binding protein-like domain 168 332 8.4E-13 T 14-10-2018 MB46_08835 87abeb4bf3fcd3fd0bcf3ad148014399 315 SUPERFAMILY SSF53850 89 300 2.35E-26 T 14-10-2018 MB46_08835 87abeb4bf3fcd3fd0bcf3ad148014399 315 Gene3D G3DSA:1.10.10.10 1 91 4.2E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_08835 87abeb4bf3fcd3fd0bcf3ad148014399 315 Pfam PF03466 LysR substrate binding domain 88 293 7.5E-25 T 14-10-2018 IPR005119 LysR, substrate-binding MB46_08835 87abeb4bf3fcd3fd0bcf3ad148014399 315 Gene3D G3DSA:3.40.190.290 93 299 1.3E-23 T 14-10-2018 MB46_08835 87abeb4bf3fcd3fd0bcf3ad148014399 315 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 62 1.6E-16 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MB46_08835 87abeb4bf3fcd3fd0bcf3ad148014399 315 SUPERFAMILY SSF46785 2 112 1.44E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_05190 e761de5d4a04190de801cd76d99e3712 532 Pfam PF00005 ABC transporter 343 471 2.8E-24 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_05190 e761de5d4a04190de801cd76d99e3712 532 Gene3D G3DSA:3.40.50.300 291 520 9.5E-54 T 14-10-2018 MB46_05190 e761de5d4a04190de801cd76d99e3712 532 SUPERFAMILY SSF52540 330 516 7.48E-46 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_05190 e761de5d4a04190de801cd76d99e3712 532 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_05190 e761de5d4a04190de801cd76d99e3712 532 SMART SM00382 26 231 1.5E-8 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_05190 e761de5d4a04190de801cd76d99e3712 532 SMART SM00382 350 515 7.1E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_05190 e761de5d4a04190de801cd76d99e3712 532 ProSitePatterns PS00211 ABC transporters family signature. 443 457 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_05190 e761de5d4a04190de801cd76d99e3712 532 Pfam PF00005 ABC transporter 18 187 7.7E-25 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_05190 e761de5d4a04190de801cd76d99e3712 532 Pfam PF12848 ABC transporter 230 309 5.5E-9 T 14-10-2018 IPR032781 ABC-transporter extension domain MB46_05190 e761de5d4a04190de801cd76d99e3712 532 SUPERFAMILY SSF52540 2 231 4.62E-44 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_11160 8347b5feba24489c037b68d157798ad1 282 SUPERFAMILY SSF52540 1 246 2.5E-72 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_11160 8347b5feba24489c037b68d157798ad1 282 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 226 261 4.6E-6 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MB46_11160 8347b5feba24489c037b68d157798ad1 282 SMART SM00382 33 224 1.5E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_11160 8347b5feba24489c037b68d157798ad1 282 Pfam PF00005 ABC transporter 24 174 1.4E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_11160 8347b5feba24489c037b68d157798ad1 282 Gene3D G3DSA:3.40.50.300 1 280 1.7E-84 T 14-10-2018 MB46_11160 8347b5feba24489c037b68d157798ad1 282 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_06405 01985a5be9784f8948bfa75284d476ed 333 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 9 306 4.4E-102 T 14-10-2018 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 MB46_06405 01985a5be9784f8948bfa75284d476ed 333 SMART SM00382 26 217 1.2E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_06405 01985a5be9784f8948bfa75284d476ed 333 Gene3D G3DSA:3.40.50.300 1 240 4.4E-65 T 14-10-2018 MB46_06405 01985a5be9784f8948bfa75284d476ed 333 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_06405 01985a5be9784f8948bfa75284d476ed 333 SUPERFAMILY SSF52540 2 224 1.07E-58 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_06405 01985a5be9784f8948bfa75284d476ed 333 Pfam PF00005 ABC transporter 17 160 1.3E-26 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_10780 b5866323120fd05bd5b04dd32d3c0a5a 263 Pfam PF00005 ABC transporter 33 175 1.1E-22 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_10780 b5866323120fd05bd5b04dd32d3c0a5a 263 SMART SM00382 41 223 4.0E-8 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_10780 b5866323120fd05bd5b04dd32d3c0a5a 263 SUPERFAMILY SSF52540 15 239 7.3E-56 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_10780 b5866323120fd05bd5b04dd32d3c0a5a 263 Gene3D G3DSA:3.40.50.300 9 252 2.0E-60 T 14-10-2018 MB46_13440 fce2da2621c8ddf3c69b86c24a338465 102 Gene3D G3DSA:3.30.70.600 1 102 2.0E-36 T 14-10-2018 IPR036838 Ribosomal protein S10 domain superfamily MB46_13440 fce2da2621c8ddf3c69b86c24a338465 102 ProSitePatterns PS00361 Ribosomal protein S10 signature. 29 44 - T 14-10-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MB46_13440 fce2da2621c8ddf3c69b86c24a338465 102 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 4 101 3.2E-45 T 14-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MB46_13440 fce2da2621c8ddf3c69b86c24a338465 102 SUPERFAMILY SSF54999 5 102 2.75E-37 T 14-10-2018 IPR036838 Ribosomal protein S10 domain superfamily MB46_13440 fce2da2621c8ddf3c69b86c24a338465 102 SMART SM01403 7 101 8.8E-55 T 14-10-2018 IPR027486 Ribosomal protein S10 domain MB46_13440 fce2da2621c8ddf3c69b86c24a338465 102 Pfam PF00338 Ribosomal protein S10p/S20e 7 101 1.2E-34 T 14-10-2018 IPR027486 Ribosomal protein S10 domain MB46_13440 fce2da2621c8ddf3c69b86c24a338465 102 PRINTS PR00971 Ribosomal protein S10 family signature 5 18 2.1E-21 T 14-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MB46_13440 fce2da2621c8ddf3c69b86c24a338465 102 PRINTS PR00971 Ribosomal protein S10 family signature 40 55 2.1E-21 T 14-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MB46_13440 fce2da2621c8ddf3c69b86c24a338465 102 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 2.1E-21 T 14-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MB46_13440 fce2da2621c8ddf3c69b86c24a338465 102 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 3 102 27.026 T 14-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MB46_19420 33a057c4fca890aa12d13edc84a30c75 494 Pfam PF16569 Gram-positive pilin backbone subunit 2, Cna-B-like domain 205 297 5.4E-7 T 14-10-2018 IPR032334 Gram-positive pilin backbone subunit 2, Cna-B-like domain MB46_19420 33a057c4fca890aa12d13edc84a30c75 494 TIGRFAM TIGR04226 RrgB_K2N_iso_D2: fimbrial isopeptide formation D2 domain 192 307 1.1E-14 T 14-10-2018 IPR026466 Fimbrial isopeptide formation D2 domain MB46_19420 33a057c4fca890aa12d13edc84a30c75 494 Gene3D G3DSA:2.60.40.740 189 330 1.3E-29 T 14-10-2018 MB46_19420 33a057c4fca890aa12d13edc84a30c75 494 Gene3D G3DSA:2.60.40.10 33 188 5.0E-46 T 14-10-2018 IPR013783 Immunoglobulin-like fold MB46_19420 33a057c4fca890aa12d13edc84a30c75 494 Gene3D G3DSA:2.60.40.10 331 453 3.8E-30 T 14-10-2018 IPR013783 Immunoglobulin-like fold MB46_07420 33a057c4fca890aa12d13edc84a30c75 494 Pfam PF16569 Gram-positive pilin backbone subunit 2, Cna-B-like domain 205 297 5.4E-7 T 14-10-2018 IPR032334 Gram-positive pilin backbone subunit 2, Cna-B-like domain MB46_07420 33a057c4fca890aa12d13edc84a30c75 494 TIGRFAM TIGR04226 RrgB_K2N_iso_D2: fimbrial isopeptide formation D2 domain 192 307 1.1E-14 T 14-10-2018 IPR026466 Fimbrial isopeptide formation D2 domain MB46_07420 33a057c4fca890aa12d13edc84a30c75 494 Gene3D G3DSA:2.60.40.740 189 330 1.3E-29 T 14-10-2018 MB46_07420 33a057c4fca890aa12d13edc84a30c75 494 Gene3D G3DSA:2.60.40.10 33 188 5.0E-46 T 14-10-2018 IPR013783 Immunoglobulin-like fold MB46_07420 33a057c4fca890aa12d13edc84a30c75 494 Gene3D G3DSA:2.60.40.10 331 453 3.8E-30 T 14-10-2018 IPR013783 Immunoglobulin-like fold MB46_09740 46bc255b4bcd661040073868711a955a 891 Gene3D G3DSA:3.40.50.12780 341 775 1.2E-57 T 14-10-2018 MB46_09740 46bc255b4bcd661040073868711a955a 891 Pfam PF00501 AMP-binding enzyme 349 778 3.9E-53 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 MB46_09740 46bc255b4bcd661040073868711a955a 891 SUPERFAMILY SSF56801 349 880 2.88E-65 T 14-10-2018 MB46_09740 46bc255b4bcd661040073868711a955a 891 ProSitePatterns PS00455 Putative AMP-binding domain signature. 519 530 - T 14-10-2018 IPR020845 AMP-binding, conserved site MB46_09740 46bc255b4bcd661040073868711a955a 891 Pfam PF00561 alpha/beta hydrolase fold 64 310 1.2E-16 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MB46_09740 46bc255b4bcd661040073868711a955a 891 SUPERFAMILY SSF53474 44 310 6.02E-41 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_09740 46bc255b4bcd661040073868711a955a 891 Gene3D G3DSA:3.40.50.1820 24 321 3.0E-49 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_09300 73af3286997d0daeaa9b39db9411de51 265 TIGRFAM TIGR03704 PrmC_rel_meth: putative protein-(glutamine-N5) methyltransferase, unknown substrate-specific 6 262 2.6E-97 T 14-10-2018 IPR022446 Conserved hypothetical protein CHP03704, protein-(glutamine-N5) methyltransferase MB46_09300 73af3286997d0daeaa9b39db9411de51 265 Pfam PF05175 Methyltransferase small domain 84 184 2.8E-8 T 14-10-2018 IPR007848 Methyltransferase small domain GO:0008168 MB46_09300 73af3286997d0daeaa9b39db9411de51 265 SUPERFAMILY SSF53335 42 227 5.27E-40 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MB46_09300 73af3286997d0daeaa9b39db9411de51 265 Gene3D G3DSA:3.40.50.150 62 262 3.7E-42 T 14-10-2018 MB46_09300 73af3286997d0daeaa9b39db9411de51 265 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 36 243 2.1E-40 T 14-10-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 MB46_09390 c54f553679f3bf87adea295f72a0d63f 311 TIGRFAM TIGR01139 cysK: cysteine synthase A 9 306 1.0E-131 T 14-10-2018 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 MB46_09390 c54f553679f3bf87adea295f72a0d63f 311 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 34 52 - T 14-10-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 MB46_09390 c54f553679f3bf87adea295f72a0d63f 311 Gene3D G3DSA:3.40.50.1100 46 145 3.9E-120 T 14-10-2018 MB46_09390 c54f553679f3bf87adea295f72a0d63f 311 Gene3D G3DSA:3.40.50.1100 7 302 3.9E-120 T 14-10-2018 MB46_09390 c54f553679f3bf87adea295f72a0d63f 311 SUPERFAMILY SSF53686 3 308 2.49E-100 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme MB46_09390 c54f553679f3bf87adea295f72a0d63f 311 TIGRFAM TIGR01136 cysKM: cysteine synthase 9 306 2.5E-128 T 14-10-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 MB46_09390 c54f553679f3bf87adea295f72a0d63f 311 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 8 295 1.4E-63 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme MB46_13165 16570348ae29cb43a8d47180fe553964 1041 Gene3D G3DSA:3.40.50.200 173 682 3.2E-134 T 14-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 MB46_13165 16570348ae29cb43a8d47180fe553964 1041 PRINTS PR00723 Subtilisin serine protease family (S8) signature 277 290 1.0E-14 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related MB46_13165 16570348ae29cb43a8d47180fe553964 1041 PRINTS PR00723 Subtilisin serine protease family (S8) signature 171 190 1.0E-14 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related MB46_13165 16570348ae29cb43a8d47180fe553964 1041 PRINTS PR00723 Subtilisin serine protease family (S8) signature 604 620 1.0E-14 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related MB46_13165 16570348ae29cb43a8d47180fe553964 1041 Gene3D G3DSA:2.60.120.380 854 943 3.9E-5 T 14-10-2018 MB46_13165 16570348ae29cb43a8d47180fe553964 1041 Pfam PF00082 Subtilase family 171 660 5.2E-43 T 14-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 MB46_13165 16570348ae29cb43a8d47180fe553964 1041 Pfam PF02225 PA domain 459 521 3.3E-8 T 14-10-2018 IPR003137 PA domain MB46_13165 16570348ae29cb43a8d47180fe553964 1041 SUPERFAMILY SSF54897 90 140 6.8E-6 T 14-10-2018 MB46_13165 16570348ae29cb43a8d47180fe553964 1041 Gene3D G3DSA:3.50.30.30 412 549 3.2E-134 T 14-10-2018 MB46_13165 16570348ae29cb43a8d47180fe553964 1041 Gene3D G3DSA:2.60.40.2310 684 799 3.3E-18 T 14-10-2018 MB46_13165 16570348ae29cb43a8d47180fe553964 1041 Gene3D G3DSA:3.30.70.80 38 141 5.7E-10 T 14-10-2018 IPR037045 Peptidase S8 propeptide/proteinase inhibitor I9 superfamily Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 MB46_13165 16570348ae29cb43a8d47180fe553964 1041 SUPERFAMILY SSF52743 167 672 5.63E-62 T 14-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 MB46_13165 16570348ae29cb43a8d47180fe553964 1041 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 605 615 - T 14-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site MB46_13165 16570348ae29cb43a8d47180fe553964 1041 Pfam PF05922 Peptidase inhibitor I9 44 139 6.2E-8 T 14-10-2018 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 MB46_08805 c30b3403b91605d5af6a6454c501f159 706 Pfam PF02867 Ribonucleotide reductase, barrel domain 170 685 3.2E-141 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MB46_08805 c30b3403b91605d5af6a6454c501f159 706 TIGRFAM TIGR04170 RNR_1b_NrdE: ribonucleoside-diphosphate reductase, class 1b, alpha subunit 10 706 0.0 T 14-10-2018 IPR026459 Ribonucleotide reductase, class 1b, subunit NrdE KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MB46_08805 c30b3403b91605d5af6a6454c501f159 706 PRINTS PR01183 Ribonucleotide reductase large chain signature 487 510 3.6E-30 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MB46_08805 c30b3403b91605d5af6a6454c501f159 706 PRINTS PR01183 Ribonucleotide reductase large chain signature 459 481 3.6E-30 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MB46_08805 c30b3403b91605d5af6a6454c501f159 706 PRINTS PR01183 Ribonucleotide reductase large chain signature 376 387 3.6E-30 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MB46_08805 c30b3403b91605d5af6a6454c501f159 706 PRINTS PR01183 Ribonucleotide reductase large chain signature 245 264 3.6E-30 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MB46_08805 c30b3403b91605d5af6a6454c501f159 706 PRINTS PR01183 Ribonucleotide reductase large chain signature 420 443 3.6E-30 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MB46_08805 c30b3403b91605d5af6a6454c501f159 706 PRINTS PR01183 Ribonucleotide reductase large chain signature 569 596 3.6E-30 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MB46_08805 c30b3403b91605d5af6a6454c501f159 706 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 97 688 1.4E-159 T 14-10-2018 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MB46_08805 c30b3403b91605d5af6a6454c501f159 706 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 95 165 4.8E-11 T 14-10-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MB46_08805 c30b3403b91605d5af6a6454c501f159 706 SUPERFAMILY SSF48168 10 168 3.01E-56 T 14-10-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MB46_08805 c30b3403b91605d5af6a6454c501f159 706 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 558 580 - T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MB46_08805 c30b3403b91605d5af6a6454c501f159 706 Gene3D G3DSA:1.10.1650.20 288 339 1.3E-28 T 14-10-2018 MB46_08805 c30b3403b91605d5af6a6454c501f159 706 Pfam PF08343 Ribonucleotide reductase N-terminal 10 91 4.2E-31 T 14-10-2018 IPR013554 Ribonucleotide reductase N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MB46_08805 c30b3403b91605d5af6a6454c501f159 706 SUPERFAMILY SSF51998 169 690 1.46E-184 T 14-10-2018 MB46_11110 2509bf61633da1d296af5226bf8512e3 188 Gene3D G3DSA:3.40.50.300 10 186 8.6E-62 T 14-10-2018 MB46_11110 2509bf61633da1d296af5226bf8512e3 188 Pfam PF01202 Shikimate kinase 31 176 2.3E-13 T 14-10-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 MB46_11110 2509bf61633da1d296af5226bf8512e3 188 TIGRFAM TIGR01313 therm_gnt_kin: carbohydrate kinase, thermoresistant glucokinase family 25 178 8.8E-54 T 14-10-2018 IPR006001 Carbohydrate kinase, thermoresistant glucokinase GO:0005975|GO:0016301 KEGG: 00030+2.7.1.12|MetaCyc: PWY-5530 MB46_11110 2509bf61633da1d296af5226bf8512e3 188 SUPERFAMILY SSF52540 21 180 2.0E-24 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_11110 2509bf61633da1d296af5226bf8512e3 188 PRINTS PR01100 Shikimate kinase family signature 25 40 2.4E-5 T 14-10-2018 MB46_11110 2509bf61633da1d296af5226bf8512e3 188 PRINTS PR01100 Shikimate kinase family signature 117 134 2.4E-5 T 14-10-2018 MB46_01870 d6d6fae073d0a05703fcfc6ff13e7404 196 SUPERFAMILY SSF46894 132 194 1.43E-18 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MB46_01870 d6d6fae073d0a05703fcfc6ff13e7404 196 SMART SM00448 1 98 4.4E-12 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MB46_01870 d6d6fae073d0a05703fcfc6ff13e7404 196 SUPERFAMILY SSF52172 5 113 2.7E-22 T 14-10-2018 IPR011006 CheY-like superfamily MB46_01870 d6d6fae073d0a05703fcfc6ff13e7404 196 Pfam PF00072 Response regulator receiver domain 8 99 2.7E-18 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MB46_01870 d6d6fae073d0a05703fcfc6ff13e7404 196 ProSitePatterns PS00622 LuxR-type HTH domain signature. 154 181 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_01870 d6d6fae073d0a05703fcfc6ff13e7404 196 Gene3D G3DSA:3.40.50.12740 1 196 3.4E-55 T 14-10-2018 MB46_01870 d6d6fae073d0a05703fcfc6ff13e7404 196 SMART SM00421 137 194 3.2E-21 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_01870 d6d6fae073d0a05703fcfc6ff13e7404 196 Pfam PF00196 Bacterial regulatory proteins, luxR family 139 192 3.7E-17 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_01870 d6d6fae073d0a05703fcfc6ff13e7404 196 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 154 170 1.1E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_01870 d6d6fae073d0a05703fcfc6ff13e7404 196 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 140 154 1.1E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_01870 d6d6fae073d0a05703fcfc6ff13e7404 196 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 170 182 1.1E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_03235 7ab7eb2e6e25110a66f0c906e26e1f83 461 PRINTS PR01043 Glycyl-tRNA synthetase signature 138 150 2.2E-52 T 14-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MB46_03235 7ab7eb2e6e25110a66f0c906e26e1f83 461 PRINTS PR01043 Glycyl-tRNA synthetase signature 404 423 2.2E-52 T 14-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MB46_03235 7ab7eb2e6e25110a66f0c906e26e1f83 461 PRINTS PR01043 Glycyl-tRNA synthetase signature 159 176 2.2E-52 T 14-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MB46_03235 7ab7eb2e6e25110a66f0c906e26e1f83 461 PRINTS PR01043 Glycyl-tRNA synthetase signature 191 208 2.2E-52 T 14-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MB46_03235 7ab7eb2e6e25110a66f0c906e26e1f83 461 PRINTS PR01043 Glycyl-tRNA synthetase signature 208 218 2.2E-52 T 14-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MB46_03235 7ab7eb2e6e25110a66f0c906e26e1f83 461 PRINTS PR01043 Glycyl-tRNA synthetase signature 26 40 2.2E-52 T 14-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MB46_03235 7ab7eb2e6e25110a66f0c906e26e1f83 461 PRINTS PR01043 Glycyl-tRNA synthetase signature 318 330 2.2E-52 T 14-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MB46_03235 7ab7eb2e6e25110a66f0c906e26e1f83 461 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 158 333 1.5E-8 T 14-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 MB46_03235 7ab7eb2e6e25110a66f0c906e26e1f83 461 SUPERFAMILY SSF55681 6 370 4.02E-119 T 14-10-2018 MB46_03235 7ab7eb2e6e25110a66f0c906e26e1f83 461 TIGRFAM TIGR00389 glyS_dimeric: glycine--tRNA ligase 8 232 8.1E-80 T 14-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MB46_03235 7ab7eb2e6e25110a66f0c906e26e1f83 461 Gene3D G3DSA:3.40.50.800 365 460 8.5E-34 T 14-10-2018 IPR036621 Anticodon-binding domain superfamily MB46_03235 7ab7eb2e6e25110a66f0c906e26e1f83 461 Hamap MF_00253_B Glycine--tRNA ligase [glyQS]. 4 459 47.982 T 14-10-2018 IPR022961 Glycine-tRNA ligase, bacterial GO:0004820 KEGG: 00970+6.1.1.14 MB46_03235 7ab7eb2e6e25110a66f0c906e26e1f83 461 Pfam PF03129 Anticodon binding domain 367 455 8.9E-23 T 14-10-2018 IPR004154 Anticodon-binding MB46_03235 7ab7eb2e6e25110a66f0c906e26e1f83 461 SUPERFAMILY SSF52954 354 458 6.19E-35 T 14-10-2018 MB46_17080 a9423d4c34ccb3a3702bf82802efe055 326 SMART SM00271 9 67 7.2E-29 T 14-10-2018 IPR001623 DnaJ domain MB46_17080 a9423d4c34ccb3a3702bf82802efe055 326 Gene3D G3DSA:2.60.260.20 146 213 4.0E-15 T 14-10-2018 MB46_17080 a9423d4c34ccb3a3702bf82802efe055 326 PRINTS PR00625 DnaJ domain signature 12 30 1.7E-20 T 14-10-2018 IPR001623 DnaJ domain MB46_17080 a9423d4c34ccb3a3702bf82802efe055 326 PRINTS PR00625 DnaJ domain signature 30 45 1.7E-20 T 14-10-2018 IPR001623 DnaJ domain MB46_17080 a9423d4c34ccb3a3702bf82802efe055 326 PRINTS PR00625 DnaJ domain signature 47 67 1.7E-20 T 14-10-2018 IPR001623 DnaJ domain MB46_17080 a9423d4c34ccb3a3702bf82802efe055 326 Gene3D G3DSA:1.10.287.110 7 116 2.8E-32 T 14-10-2018 IPR036869 Chaperone J-domain superfamily MB46_17080 a9423d4c34ccb3a3702bf82802efe055 326 SUPERFAMILY SSF46565 7 110 4.58E-31 T 14-10-2018 IPR036869 Chaperone J-domain superfamily MB46_17080 a9423d4c34ccb3a3702bf82802efe055 326 SUPERFAMILY SSF49493 220 303 3.14E-19 T 14-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 MB46_17080 a9423d4c34ccb3a3702bf82802efe055 326 Pfam PF00226 DnaJ domain 10 72 8.1E-27 T 14-10-2018 IPR001623 DnaJ domain MB46_17080 a9423d4c34ccb3a3702bf82802efe055 326 SUPERFAMILY SSF49493 145 221 1.28E-15 T 14-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 MB46_17080 a9423d4c34ccb3a3702bf82802efe055 326 Gene3D G3DSA:2.60.260.20 215 319 3.5E-26 T 14-10-2018 MB46_17080 a9423d4c34ccb3a3702bf82802efe055 326 Pfam PF01556 DnaJ C terminal domain 157 293 4.5E-32 T 14-10-2018 IPR002939 Chaperone DnaJ, C-terminal MB46_18050 44e713c14e05a276603f6bddf560483a 246 Gene3D G3DSA:3.90.1200.10 106 205 8.6E-7 T 14-10-2018 MB46_18050 44e713c14e05a276603f6bddf560483a 246 SUPERFAMILY SSF56112 9 228 3.06E-24 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily MB46_18050 44e713c14e05a276603f6bddf560483a 246 Pfam PF04655 Aminoglycoside/hydroxyurea antibiotic resistance kinase 5 231 9.6E-49 T 14-10-2018 IPR006748 Aminoglycoside/hydroxyurea antibiotic resistance kinase GO:0006468|GO:0016773|GO:0019748 MB46_19195 6f76b3c0aefd1442ce19ff2e30b69314 216 ProSitePatterns PS01228 Hypothetical cof family signature 1. 10 21 - T 14-10-2018 MB46_19195 6f76b3c0aefd1442ce19ff2e30b69314 216 Gene3D G3DSA:1.20.1440.100 22 97 3.8E-32 T 14-10-2018 MB46_19195 6f76b3c0aefd1442ce19ff2e30b69314 216 Gene3D G3DSA:3.40.50.1000 13 208 3.8E-32 T 14-10-2018 IPR023214 HAD superfamily MB46_19195 6f76b3c0aefd1442ce19ff2e30b69314 216 Pfam PF12710 haloacid dehalogenase-like hydrolase 13 195 9.0E-20 T 14-10-2018 MB46_19195 6f76b3c0aefd1442ce19ff2e30b69314 216 SUPERFAMILY SSF56784 10 206 7.21E-12 T 14-10-2018 IPR036412 HAD-like superfamily MB46_19995 6f76b3c0aefd1442ce19ff2e30b69314 216 ProSitePatterns PS01228 Hypothetical cof family signature 1. 10 21 - T 14-10-2018 MB46_19995 6f76b3c0aefd1442ce19ff2e30b69314 216 Gene3D G3DSA:1.20.1440.100 22 97 3.8E-32 T 14-10-2018 MB46_19995 6f76b3c0aefd1442ce19ff2e30b69314 216 Gene3D G3DSA:3.40.50.1000 13 208 3.8E-32 T 14-10-2018 IPR023214 HAD superfamily MB46_19995 6f76b3c0aefd1442ce19ff2e30b69314 216 Pfam PF12710 haloacid dehalogenase-like hydrolase 13 195 9.0E-20 T 14-10-2018 MB46_19995 6f76b3c0aefd1442ce19ff2e30b69314 216 SUPERFAMILY SSF56784 10 206 7.21E-12 T 14-10-2018 IPR036412 HAD-like superfamily MB46_10225 84053c1b17020d0d73763e9f37a07167 629 SUPERFAMILY SSF52518 50 228 6.99E-60 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold MB46_10225 84053c1b17020d0d73763e9f37a07167 629 Gene3D G3DSA:3.40.50.1220 234 405 2.6E-57 T 14-10-2018 MB46_10225 84053c1b17020d0d73763e9f37a07167 629 SUPERFAMILY SSF52467 233 407 3.96E-59 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily MB46_10225 84053c1b17020d0d73763e9f37a07167 629 SUPERFAMILY SSF52518 417 623 7.68E-66 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold MB46_10225 84053c1b17020d0d73763e9f37a07167 629 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 476 495 - T 14-10-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 MB46_10225 84053c1b17020d0d73763e9f37a07167 629 Gene3D G3DSA:3.40.50.970 410 624 2.8E-68 T 14-10-2018 MB46_10225 84053c1b17020d0d73763e9f37a07167 629 Gene3D G3DSA:3.40.50.970 46 220 1.7E-67 T 14-10-2018 MB46_10225 84053c1b17020d0d73763e9f37a07167 629 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 241 374 1.2E-45 T 14-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 MB46_10225 84053c1b17020d0d73763e9f37a07167 629 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 51 213 3.7E-54 T 14-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 MB46_10225 84053c1b17020d0d73763e9f37a07167 629 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 439 593 3.6E-48 T 14-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 MB46_10225 84053c1b17020d0d73763e9f37a07167 629 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 51 615 1.6E-221 T 14-10-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 MB46_01895 9ee10ac40e4cefea02662fad170731a4 342 SUPERFAMILY SSF52374 9 334 2.61E-96 T 14-10-2018 MB46_01895 9ee10ac40e4cefea02662fad170731a4 342 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 7 335 41.603 T 14-10-2018 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2|Reactome: R-HSA-379726 MB46_01895 9ee10ac40e4cefea02662fad170731a4 342 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 71 90 4.0E-25 T 14-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 MB46_01895 9ee10ac40e4cefea02662fad170731a4 342 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 201 211 4.0E-25 T 14-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 MB46_01895 9ee10ac40e4cefea02662fad170731a4 342 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 148 169 4.0E-25 T 14-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 MB46_01895 9ee10ac40e4cefea02662fad170731a4 342 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 21 37 4.0E-25 T 14-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 MB46_01895 9ee10ac40e4cefea02662fad170731a4 342 Gene3D G3DSA:1.10.240.10 192 302 6.5E-130 T 14-10-2018 MB46_01895 9ee10ac40e4cefea02662fad170731a4 342 Pfam PF00579 tRNA synthetases class I (W and Y) 7 289 8.0E-78 T 14-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 MB46_01895 9ee10ac40e4cefea02662fad170731a4 342 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 7 334 7.9E-106 T 14-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 MB46_01895 9ee10ac40e4cefea02662fad170731a4 342 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 16 26 - T 14-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 MB46_01895 9ee10ac40e4cefea02662fad170731a4 342 Gene3D G3DSA:3.40.50.620 10 333 6.5E-130 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MB46_03190 fc33afd8684ab81ce27dbc1a1b2c98a5 816 SUPERFAMILY SSF158832 20 340 4.58E-100 T 14-10-2018 MB46_03190 fc33afd8684ab81ce27dbc1a1b2c98a5 816 SUPERFAMILY SSF47781 585 655 1.29E-15 T 14-10-2018 IPR010994 RuvA domain 2-like MB46_03190 fc33afd8684ab81ce27dbc1a1b2c98a5 816 Pfam PF09371 Tex-like protein N-terminal domain 25 208 5.3E-61 T 14-10-2018 IPR018974 Tex-like protein, N-terminal MB46_03190 fc33afd8684ab81ce27dbc1a1b2c98a5 816 SUPERFAMILY SSF53098 341 493 1.97E-47 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily MB46_03190 fc33afd8684ab81ce27dbc1a1b2c98a5 816 SMART SM00316 673 744 3.0E-25 T 14-10-2018 IPR022967 RNA-binding domain, S1 MB46_03190 fc33afd8684ab81ce27dbc1a1b2c98a5 816 Gene3D G3DSA:1.10.150.310 523 654 3.2E-43 T 14-10-2018 MB46_03190 fc33afd8684ab81ce27dbc1a1b2c98a5 816 SUPERFAMILY SSF50249 662 749 2.54E-24 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold MB46_03190 fc33afd8684ab81ce27dbc1a1b2c98a5 816 Pfam PF00575 S1 RNA binding domain 673 744 1.0E-19 T 14-10-2018 IPR003029 S1 domain GO:0003676 MB46_03190 fc33afd8684ab81ce27dbc1a1b2c98a5 816 Gene3D G3DSA:1.10.3500.10 128 522 3.1E-137 T 14-10-2018 IPR023323 Tex-like domain superfamily MB46_03190 fc33afd8684ab81ce27dbc1a1b2c98a5 816 SUPERFAMILY SSF47781 494 581 1.33E-25 T 14-10-2018 IPR010994 RuvA domain 2-like MB46_03190 fc33afd8684ab81ce27dbc1a1b2c98a5 816 Pfam PF12836 Helix-hairpin-helix motif 515 579 3.0E-27 T 14-10-2018 MB46_03190 fc33afd8684ab81ce27dbc1a1b2c98a5 816 Gene3D G3DSA:2.40.50.140 655 748 8.5E-28 T 14-10-2018 MB46_03190 fc33afd8684ab81ce27dbc1a1b2c98a5 816 Gene3D G3DSA:3.30.420.140 344 475 3.1E-137 T 14-10-2018 IPR037027 YqgF/RNase H-like domain superfamily GO:0006139 MB46_03190 fc33afd8684ab81ce27dbc1a1b2c98a5 816 Gene3D G3DSA:1.10.10.650 16 125 3.5E-35 T 14-10-2018 IPR023319 Tex-like protein, HTH domain superfamily MB46_03190 fc33afd8684ab81ce27dbc1a1b2c98a5 816 SMART SM00732 345 448 3.9E-32 T 14-10-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 MB46_03190 fc33afd8684ab81ce27dbc1a1b2c98a5 816 Pfam PF16921 Tex protein YqgF-like domain 346 475 8.9E-49 T 14-10-2018 IPR032639 Tex protein, YqgF-like domain MB46_10230 7fbfaa501b20e3bdb8f35178bbba7b2f 559 Gene3D G3DSA:3.50.30.80 381 529 8.3E-51 T 14-10-2018 MB46_10230 7fbfaa501b20e3bdb8f35178bbba7b2f 559 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 121 131 - T 14-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 MB46_10230 7fbfaa501b20e3bdb8f35178bbba7b2f 559 SUPERFAMILY SSF143975 2 380 6.93E-135 T 14-10-2018 IPR037237 IlvD/EDD, N-terminal domain KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 MB46_10230 7fbfaa501b20e3bdb8f35178bbba7b2f 559 SUPERFAMILY SSF52016 381 558 6.91E-56 T 14-10-2018 MB46_10230 7fbfaa501b20e3bdb8f35178bbba7b2f 559 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 16 556 2.2E-216 T 14-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 MB46_10230 7fbfaa501b20e3bdb8f35178bbba7b2f 559 Pfam PF00920 Dehydratase family 33 556 1.4E-210 T 14-10-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 MB46_10230 7fbfaa501b20e3bdb8f35178bbba7b2f 559 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 3 559 45.484 T 14-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 MB46_10230 7fbfaa501b20e3bdb8f35178bbba7b2f 559 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 467 478 - T 14-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 MB46_05280 142ff6e75809dc8b978dacb875e46f14 476 SUPERFAMILY SSF53448 4 286 2.07E-65 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MB46_05280 142ff6e75809dc8b978dacb875e46f14 476 SUPERFAMILY SSF51161 305 413 2.36E-17 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily MB46_05280 142ff6e75809dc8b978dacb875e46f14 476 Pfam PF00483 Nucleotidyl transferase 8 282 1.1E-63 T 14-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 MB46_05280 142ff6e75809dc8b978dacb875e46f14 476 Hamap MF_00624 Glucose-1-phosphate adenylyltransferase [glgC]. 3 416 44.622 T 14-10-2018 IPR023049 Glucose-1-phosphate adenylyltransferase GlgC, bacterial GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 MB46_05280 142ff6e75809dc8b978dacb875e46f14 476 ProSitePatterns PS00810 ADP-glucose pyrophosphorylase signature 3. 202 212 - T 14-10-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 MB46_05280 142ff6e75809dc8b978dacb875e46f14 476 Gene3D G3DSA:3.90.550.10 2 297 1.4E-79 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MB46_05280 142ff6e75809dc8b978dacb875e46f14 476 ProSitePatterns PS00808 ADP-glucose pyrophosphorylase signature 1. 12 31 - T 14-10-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 MB46_05280 142ff6e75809dc8b978dacb875e46f14 476 TIGRFAM TIGR02091 glgC: glucose-1-phosphate adenylyltransferase 6 389 4.0E-132 T 14-10-2018 IPR011831 Glucose-1-phosphate adenylyltransferase GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 MB46_05280 142ff6e75809dc8b978dacb875e46f14 476 Gene3D G3DSA:2.160.10.10 298 421 9.7E-34 T 14-10-2018 MB46_05280 142ff6e75809dc8b978dacb875e46f14 476 ProSitePatterns PS00809 ADP-glucose pyrophosphorylase signature 2. 96 104 - T 14-10-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 MB46_02250 1352159a86cecbb2aa54080519583c4e 93 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 23 92 18.398 T 14-10-2018 IPR003482 Transcription factor WhiB MB46_02250 1352159a86cecbb2aa54080519583c4e 93 Pfam PF02467 Transcription factor WhiB 25 88 3.0E-26 T 14-10-2018 IPR034768 WhiB-like iron-sulfur binding domain MB46_17655 de6d175d318a9ebf872d5c283248d961 670 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 22 141 3.9E-16 T 14-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 MB46_17655 de6d175d318a9ebf872d5c283248d961 670 Pfam PF14100 Methane oxygenase PmoA 400 665 4.2E-66 T 14-10-2018 IPR029475 Methane oxygenase PmoA MB46_17655 de6d175d318a9ebf872d5c283248d961 670 SUPERFAMILY SSF55347 152 301 2.07E-7 T 14-10-2018 MB46_17655 de6d175d318a9ebf872d5c283248d961 670 Gene3D G3DSA:3.40.50.720 17 153 1.0E-24 T 14-10-2018 MB46_17655 de6d175d318a9ebf872d5c283248d961 670 Gene3D G3DSA:3.30.360.10 154 306 3.5E-18 T 14-10-2018 MB46_17655 de6d175d318a9ebf872d5c283248d961 670 SUPERFAMILY SSF51735 14 170 6.68E-29 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_08095 0fe6c7ebc7380e7e11c77c98f6996c06 474 Pfam PF00120 Glutamine synthetase, catalytic domain 105 471 5.0E-132 T 14-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MB46_08095 0fe6c7ebc7380e7e11c77c98f6996c06 474 SUPERFAMILY SSF54368 5 102 3.4E-32 T 14-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MB46_08095 0fe6c7ebc7380e7e11c77c98f6996c06 474 SUPERFAMILY SSF55931 105 473 1.86E-135 T 14-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 MB46_08095 0fe6c7ebc7380e7e11c77c98f6996c06 474 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 6 472 6.7E-194 T 14-10-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MB46_08095 0fe6c7ebc7380e7e11c77c98f6996c06 474 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 16 97 4.0E-25 T 14-10-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 MB46_08095 0fe6c7ebc7380e7e11c77c98f6996c06 474 Gene3D G3DSA:3.10.20.70 4 106 1.1E-35 T 14-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MB46_08095 0fe6c7ebc7380e7e11c77c98f6996c06 474 ProSitePatterns PS00180 Glutamine synthetase signature 1. 52 70 - T 14-10-2018 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 MB46_08095 0fe6c7ebc7380e7e11c77c98f6996c06 474 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 261 276 - T 14-10-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 MB46_08095 0fe6c7ebc7380e7e11c77c98f6996c06 474 SMART SM01230 104 383 3.6E-149 T 14-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MB46_08095 0fe6c7ebc7380e7e11c77c98f6996c06 474 Gene3D G3DSA:3.30.590.10 107 462 3.3E-146 T 14-10-2018 MB46_15865 fc8418cd14b40b77b80c6631a8ff99ef 497 Pfam PF08338 Domain of unknown function (DUF1731) 442 490 1.2E-13 T 14-10-2018 IPR013549 Domain of unknown function DUF1731 MB46_15865 fc8418cd14b40b77b80c6631a8ff99ef 497 SUPERFAMILY SSF51735 187 491 1.54E-27 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_15865 fc8418cd14b40b77b80c6631a8ff99ef 497 Gene3D G3DSA:3.30.530.20 3 182 6.8E-32 T 14-10-2018 IPR023393 START-like domain superfamily MB46_15865 fc8418cd14b40b77b80c6631a8ff99ef 497 TIGRFAM TIGR01777 yfcH: TIGR01777 family protein 188 487 5.0E-75 T 14-10-2018 IPR010099 Epimerase family protein SDR39U1 MB46_15865 fc8418cd14b40b77b80c6631a8ff99ef 497 Pfam PF01370 NAD dependent epimerase/dehydratase family 188 307 4.0E-6 T 14-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 MB46_15865 fc8418cd14b40b77b80c6631a8ff99ef 497 SUPERFAMILY SSF55961 1 170 3.17E-12 T 14-10-2018 MB46_15865 fc8418cd14b40b77b80c6631a8ff99ef 497 Gene3D G3DSA:3.40.50.720 183 480 2.1E-64 T 14-10-2018 MB46_19755 dbaeb5afbc47ccd945bacac058a2ad3f 175 Pfam PF01928 CYTH domain 4 162 3.0E-17 T 14-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 MB46_19755 dbaeb5afbc47ccd945bacac058a2ad3f 175 Gene3D G3DSA:2.40.320.10 2 173 9.7E-31 T 14-10-2018 MB46_19755 dbaeb5afbc47ccd945bacac058a2ad3f 175 SUPERFAMILY SSF55154 4 167 1.11E-30 T 14-10-2018 IPR033469 CYTH-like domain superfamily Reactome: R-HSA-196819 MB46_19755 dbaeb5afbc47ccd945bacac058a2ad3f 175 SMART SM01118 2 169 7.4E-12 T 14-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 MB46_02485 33c09cce8f02472092c8c9dfeee1b571 889 Gene3D G3DSA:1.10.10.10 771 886 2.3E-18 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_02485 33c09cce8f02472092c8c9dfeee1b571 889 SUPERFAMILY SSF46894 818 881 4.76E-16 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MB46_02485 33c09cce8f02472092c8c9dfeee1b571 889 SMART SM00421 826 883 5.6E-16 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_02485 33c09cce8f02472092c8c9dfeee1b571 889 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 859 871 2.1E-8 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_02485 33c09cce8f02472092c8c9dfeee1b571 889 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 843 859 2.1E-8 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_02485 33c09cce8f02472092c8c9dfeee1b571 889 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 829 843 2.1E-8 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_02485 33c09cce8f02472092c8c9dfeee1b571 889 Pfam PF00196 Bacterial regulatory proteins, luxR family 828 881 6.4E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_02485 33c09cce8f02472092c8c9dfeee1b571 889 ProSitePatterns PS00622 LuxR-type HTH domain signature. 843 870 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_02485 33c09cce8f02472092c8c9dfeee1b571 889 Gene3D G3DSA:3.40.50.300 3 163 1.5E-5 T 14-10-2018 MB46_02485 33c09cce8f02472092c8c9dfeee1b571 889 SUPERFAMILY SSF52540 8 218 3.31E-13 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_04155 24cdcda5f951d997a1887974dfd6938d 324 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 3 145 1.9E-42 T 14-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 MB46_04155 24cdcda5f951d997a1887974dfd6938d 324 SUPERFAMILY SSF53671 2 309 8.77E-98 T 14-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 MB46_04155 24cdcda5f951d997a1887974dfd6938d 324 PRINTS PR00102 Ornithine carbamoyltransferase signature 121 135 1.1E-29 T 14-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 MB46_04155 24cdcda5f951d997a1887974dfd6938d 324 PRINTS PR00102 Ornithine carbamoyltransferase signature 81 94 1.1E-29 T 14-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 MB46_04155 24cdcda5f951d997a1887974dfd6938d 324 PRINTS PR00102 Ornithine carbamoyltransferase signature 48 62 1.1E-29 T 14-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 MB46_04155 24cdcda5f951d997a1887974dfd6938d 324 PRINTS PR00102 Ornithine carbamoyltransferase signature 225 235 1.1E-29 T 14-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 MB46_04155 24cdcda5f951d997a1887974dfd6938d 324 PRINTS PR00102 Ornithine carbamoyltransferase signature 287 298 1.1E-29 T 14-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 MB46_04155 24cdcda5f951d997a1887974dfd6938d 324 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 2 309 75.841 T 14-10-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 MB46_04155 24cdcda5f951d997a1887974dfd6938d 324 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 3 308 2.2E-114 T 14-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 MB46_04155 24cdcda5f951d997a1887974dfd6938d 324 Gene3D G3DSA:3.40.50.1370 9 305 1.0E-113 T 14-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 MB46_04155 24cdcda5f951d997a1887974dfd6938d 324 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 152 306 3.8E-54 T 14-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 MB46_04155 24cdcda5f951d997a1887974dfd6938d 324 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 50 57 - T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MB46_04155 24cdcda5f951d997a1887974dfd6938d 324 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 273 296 2.2E-24 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MB46_04155 24cdcda5f951d997a1887974dfd6938d 324 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 132 143 2.2E-24 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MB46_04155 24cdcda5f951d997a1887974dfd6938d 324 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 50 69 2.2E-24 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MB46_04155 24cdcda5f951d997a1887974dfd6938d 324 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 261 270 2.2E-24 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MB46_04155 24cdcda5f951d997a1887974dfd6938d 324 Gene3D G3DSA:3.40.50.1370 135 295 1.0E-113 T 14-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 MB46_19940 f6c3625e4d2dec04b16f2c42e54de409 435 SUPERFAMILY SSF110849 17 98 7.5E-13 T 14-10-2018 IPR036086 ParB/Sulfiredoxin superfamily MB46_19940 f6c3625e4d2dec04b16f2c42e54de409 435 Pfam PF02195 ParB-like nuclease domain 20 96 7.6E-11 T 14-10-2018 IPR003115 ParB/Sulfiredoxin MB46_19940 f6c3625e4d2dec04b16f2c42e54de409 435 Gene3D G3DSA:1.10.10.2830 83 191 1.0E-9 T 14-10-2018 MB46_19940 f6c3625e4d2dec04b16f2c42e54de409 435 Gene3D G3DSA:3.90.1530.30 22 80 3.5E-9 T 14-10-2018 MB46_19940 f6c3625e4d2dec04b16f2c42e54de409 435 SUPERFAMILY SSF109709 89 182 2.09E-9 T 14-10-2018 MB46_19940 f6c3625e4d2dec04b16f2c42e54de409 435 SMART SM00470 8 96 2.1E-11 T 14-10-2018 IPR003115 ParB/Sulfiredoxin MB46_19940 f6c3625e4d2dec04b16f2c42e54de409 435 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 27 139 2.9E-18 T 14-10-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 MB46_15855 e5a96787942bf2ff5e777a64a3a01d74 307 Pfam PF03466 LysR substrate binding domain 89 273 4.8E-10 T 14-10-2018 IPR005119 LysR, substrate-binding MB46_15855 e5a96787942bf2ff5e777a64a3a01d74 307 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 63 2.2E-15 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MB46_15855 e5a96787942bf2ff5e777a64a3a01d74 307 SUPERFAMILY SSF46785 4 111 4.74E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_15855 e5a96787942bf2ff5e777a64a3a01d74 307 Gene3D G3DSA:3.40.190.290 88 295 4.1E-75 T 14-10-2018 MB46_15855 e5a96787942bf2ff5e777a64a3a01d74 307 SUPERFAMILY SSF53850 88 291 1.09E-17 T 14-10-2018 MB46_15855 e5a96787942bf2ff5e777a64a3a01d74 307 Gene3D G3DSA:1.10.10.10 2 85 1.8E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_15855 e5a96787942bf2ff5e777a64a3a01d74 307 TIGRFAM TIGR03298 argP: transcriptional regulator, ArgP family 5 293 2.6E-102 T 14-10-2018 IPR017685 HTH-type transcriptional regulator ArgP MB46_05690 c091282b877c5c1aac6d43efb99ff221 139 SUPERFAMILY SSF46785 1 60 2.05E-13 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_05690 c091282b877c5c1aac6d43efb99ff221 139 ProSitePatterns PS00519 AsnC-type HTH domain signature. 19 45 - T 14-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site MB46_05690 c091282b877c5c1aac6d43efb99ff221 139 Gene3D G3DSA:1.10.10.10 1 52 1.1E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_05690 c091282b877c5c1aac6d43efb99ff221 139 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 5.2E-15 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 MB46_05690 c091282b877c5c1aac6d43efb99ff221 139 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 5.2E-15 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 MB46_05690 c091282b877c5c1aac6d43efb99ff221 139 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 5.2E-15 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 MB46_05690 c091282b877c5c1aac6d43efb99ff221 139 Gene3D G3DSA:3.30.70.920 53 139 4.7E-12 T 14-10-2018 MB46_05690 c091282b877c5c1aac6d43efb99ff221 139 SUPERFAMILY SSF54909 65 139 7.91E-12 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel MB46_05690 c091282b877c5c1aac6d43efb99ff221 139 SMART SM00344 1 110 1.1E-22 T 14-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 MB46_05690 c091282b877c5c1aac6d43efb99ff221 139 Pfam PF01037 Lrp/AsnC ligand binding domain 70 139 2.0E-12 T 14-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain MB46_05690 c091282b877c5c1aac6d43efb99ff221 139 Pfam PF13404 AsnC-type helix-turn-helix domain 1 42 3.2E-15 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 MB46_00310 434052890d9e93928bf675966d5ec4db 291 Gene3D G3DSA:3.20.20.150 1 287 4.6E-44 T 14-10-2018 MB46_00310 434052890d9e93928bf675966d5ec4db 291 SUPERFAMILY SSF51658 1 285 1.57E-50 T 14-10-2018 IPR036237 Xylose isomerase-like superfamily MB46_00310 434052890d9e93928bf675966d5ec4db 291 Pfam PF01261 Xylose isomerase-like TIM barrel 22 238 3.3E-37 T 14-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain MB46_18485 600f96df018a54b0093e5054ab14e733 308 Pfam PF00849 RNA pseudouridylate synthase 96 249 1.1E-24 T 14-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 MB46_18485 600f96df018a54b0093e5054ab14e733 308 Gene3D G3DSA:3.30.2350.10 80 300 4.5E-42 T 14-10-2018 MB46_18485 600f96df018a54b0093e5054ab14e733 308 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 135 149 - T 14-10-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 MB46_18485 600f96df018a54b0093e5054ab14e733 308 SUPERFAMILY SSF55120 88 299 1.6E-46 T 14-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 MB46_09195 c569d85bf072dd397bce2f70a7529889 311 SUPERFAMILY SSF51735 117 280 1.2E-22 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_09195 c569d85bf072dd397bce2f70a7529889 311 Gene3D G3DSA:3.90.180.10 8 307 1.9E-65 T 14-10-2018 MB46_09195 c569d85bf072dd397bce2f70a7529889 311 Gene3D G3DSA:3.40.50.720 128 259 1.9E-65 T 14-10-2018 MB46_09195 c569d85bf072dd397bce2f70a7529889 311 Pfam PF13602 Zinc-binding dehydrogenase 203 308 1.4E-7 T 14-10-2018 MB46_09195 c569d85bf072dd397bce2f70a7529889 311 SMART SM00829 10 308 7.9E-10 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MB46_09195 c569d85bf072dd397bce2f70a7529889 311 SUPERFAMILY SSF50129 1 154 1.83E-35 T 14-10-2018 IPR011032 GroES-like superfamily MB46_09195 c569d85bf072dd397bce2f70a7529889 311 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 89 1.0E-5 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MB46_04285 34fc40a1bc8ecb9ed6b47ff23af333fb 132 SUPERFAMILY SSF52821 15 120 1.7E-21 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily MB46_04285 34fc40a1bc8ecb9ed6b47ff23af333fb 132 Pfam PF00581 Rhodanese-like domain 30 109 3.4E-9 T 14-10-2018 IPR001763 Rhodanese-like domain MB46_04285 34fc40a1bc8ecb9ed6b47ff23af333fb 132 Gene3D G3DSA:3.40.250.10 1 116 1.3E-23 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily MB46_04285 34fc40a1bc8ecb9ed6b47ff23af333fb 132 SMART SM00450 16 113 1.8E-12 T 14-10-2018 IPR001763 Rhodanese-like domain MB46_17665 7aaa350a2d21e52f5672f46e7a9e75a5 394 SMART SM00922 168 265 3.8E-25 T 14-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal MB46_17665 7aaa350a2d21e52f5672f46e7a9e75a5 394 SUPERFAMILY SSF51604 136 376 3.8E-71 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily MB46_17665 7aaa350a2d21e52f5672f46e7a9e75a5 394 Pfam PF13378 Enolase C-terminal domain-like 173 375 2.2E-60 T 14-10-2018 IPR029065 Enolase C-terminal domain-like MB46_17665 7aaa350a2d21e52f5672f46e7a9e75a5 394 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 51 148 2.6E-13 T 14-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain MB46_17665 7aaa350a2d21e52f5672f46e7a9e75a5 394 Gene3D G3DSA:3.30.390.10 20 376 1.6E-157 T 14-10-2018 IPR029017 Enolase-like, N-terminal MB46_17665 7aaa350a2d21e52f5672f46e7a9e75a5 394 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 215 246 - T 14-10-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 MB46_17665 7aaa350a2d21e52f5672f46e7a9e75a5 394 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 123 148 - T 14-10-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 MB46_17665 7aaa350a2d21e52f5672f46e7a9e75a5 394 Gene3D G3DSA:3.20.20.120 141 373 1.6E-157 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily MB46_17665 7aaa350a2d21e52f5672f46e7a9e75a5 394 SUPERFAMILY SSF54826 19 149 1.77E-26 T 14-10-2018 MB46_04130 bd7214eb19cc4c5f47981d67adc26d9e 324 Pfam PF00107 Zinc-binding dehydrogenase 153 254 6.3E-24 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 MB46_04130 bd7214eb19cc4c5f47981d67adc26d9e 324 Gene3D G3DSA:3.40.50.720 125 268 1.9E-107 T 14-10-2018 MB46_04130 bd7214eb19cc4c5f47981d67adc26d9e 324 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 142 163 - T 14-10-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 MB46_04130 bd7214eb19cc4c5f47981d67adc26d9e 324 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 31 97 4.6E-10 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MB46_04130 bd7214eb19cc4c5f47981d67adc26d9e 324 Gene3D G3DSA:3.90.180.10 14 321 1.9E-107 T 14-10-2018 MB46_04130 bd7214eb19cc4c5f47981d67adc26d9e 324 SUPERFAMILY SSF51735 113 268 1.64E-41 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_04130 bd7214eb19cc4c5f47981d67adc26d9e 324 SUPERFAMILY SSF50129 6 146 1.19E-35 T 14-10-2018 IPR011032 GroES-like superfamily MB46_04130 bd7214eb19cc4c5f47981d67adc26d9e 324 SMART SM00829 14 322 2.1E-28 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MB46_02490 e74dd30d368b00af7502704e266add4e 425 PIRSF PIRSF500136 3 425 6.1E-121 T 14-10-2018 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 MB46_02490 e74dd30d368b00af7502704e266add4e 425 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 325 400 4.3E-12 T 14-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 MB46_02490 e74dd30d368b00af7502704e266add4e 425 SUPERFAMILY SSF52413 313 417 9.16E-16 T 14-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 MB46_02490 e74dd30d368b00af7502704e266add4e 425 PIRSF PIRSF000124 10 421 3.9E-52 T 14-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 MB46_02490 e74dd30d368b00af7502704e266add4e 425 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 208 294 4.2E-27 T 14-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 MB46_02490 e74dd30d368b00af7502704e266add4e 425 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 12 188 2.4E-31 T 14-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 MB46_02490 e74dd30d368b00af7502704e266add4e 425 Gene3D G3DSA:3.40.50.720 206 423 8.1E-52 T 14-10-2018 MB46_02490 e74dd30d368b00af7502704e266add4e 425 SMART SM00984 325 418 2.0E-13 T 14-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 MB46_02490 e74dd30d368b00af7502704e266add4e 425 Gene3D G3DSA:3.40.50.720 1 203 4.2E-48 T 14-10-2018 MB46_02490 e74dd30d368b00af7502704e266add4e 425 SUPERFAMILY SSF48179 208 294 1.17E-26 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MB46_02490 e74dd30d368b00af7502704e266add4e 425 SUPERFAMILY SSF51735 12 200 2.73E-33 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_02490 e74dd30d368b00af7502704e266add4e 425 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 11 412 2.0E-107 T 14-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 MB46_14925 44681254a9cf2e08b5fcf48f7c72368c 429 SMART SM00788 3 422 6.9E-269 T 14-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 MB46_14925 44681254a9cf2e08b5fcf48f7c72368c 429 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 5 422 4.7E-159 T 14-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 MB46_14925 44681254a9cf2e08b5fcf48f7c72368c 429 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 429 193.106 T 14-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 MB46_14925 44681254a9cf2e08b5fcf48f7c72368c 429 SUPERFAMILY SSF52540 1 427 1.81E-166 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_14925 44681254a9cf2e08b5fcf48f7c72368c 429 Gene3D G3DSA:3.90.170.10 265 428 3.6E-64 T 14-10-2018 MB46_14925 44681254a9cf2e08b5fcf48f7c72368c 429 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 131 142 - T 14-10-2018 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 MB46_14925 44681254a9cf2e08b5fcf48f7c72368c 429 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 10 17 - T 14-10-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 MB46_14925 44681254a9cf2e08b5fcf48f7c72368c 429 Pfam PF00709 Adenylosuccinate synthetase 4 421 7.0E-170 T 14-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 MB46_14925 44681254a9cf2e08b5fcf48f7c72368c 429 Gene3D G3DSA:1.10.300.10 106 205 9.0E-94 T 14-10-2018 MB46_14925 44681254a9cf2e08b5fcf48f7c72368c 429 Gene3D G3DSA:3.40.440.10 5 257 9.0E-94 T 14-10-2018 MB46_08125 24e742e5f2ec31b5b43724eed5951006 505 SMART SM00062 62 284 1.2E-56 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MB46_08125 24e742e5f2ec31b5b43724eed5951006 505 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 322 504 9.3E-24 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_08125 24e742e5f2ec31b5b43724eed5951006 505 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 300 398 3.8E-30 T 14-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 MB46_08125 24e742e5f2ec31b5b43724eed5951006 505 Gene3D G3DSA:3.40.190.10 67 277 3.9E-71 T 14-10-2018 MB46_08125 24e742e5f2ec31b5b43724eed5951006 505 Gene3D G3DSA:1.10.3720.10 292 505 3.5E-58 T 14-10-2018 IPR035906 MetI-like superfamily MB46_08125 24e742e5f2ec31b5b43724eed5951006 505 Gene3D G3DSA:3.40.190.10 147 242 3.9E-71 T 14-10-2018 MB46_08125 24e742e5f2ec31b5b43724eed5951006 505 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 65 281 6.9E-57 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MB46_08125 24e742e5f2ec31b5b43724eed5951006 505 SUPERFAMILY SSF53850 52 282 3.04E-62 T 14-10-2018 MB46_08125 24e742e5f2ec31b5b43724eed5951006 505 SUPERFAMILY SSF161098 301 504 7.46E-48 T 14-10-2018 IPR035906 MetI-like superfamily MB46_08125 24e742e5f2ec31b5b43724eed5951006 505 SMART SM00079 62 283 2.6E-4 T 14-10-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 MB46_05465 e83399a97f371efe985f574fa023f180 243 Gene3D G3DSA:3.90.550.10 1 239 1.2E-46 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MB46_05465 e83399a97f371efe985f574fa023f180 243 SUPERFAMILY SSF53448 6 216 1.61E-43 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MB46_05465 e83399a97f371efe985f574fa023f180 243 Pfam PF00535 Glycosyl transferase family 2 6 168 3.6E-30 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MB46_18775 caf974ee2d4f2e0d1ebb2dffc0bd3cf5 273 SMART SM00382 49 241 1.9E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_18775 caf974ee2d4f2e0d1ebb2dffc0bd3cf5 273 SUPERFAMILY SSF52540 15 263 4.87E-71 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_18775 caf974ee2d4f2e0d1ebb2dffc0bd3cf5 273 ProSitePatterns PS00211 ABC transporters family signature. 164 178 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_18775 caf974ee2d4f2e0d1ebb2dffc0bd3cf5 273 Gene3D G3DSA:3.40.50.300 12 272 8.6E-84 T 14-10-2018 MB46_18775 caf974ee2d4f2e0d1ebb2dffc0bd3cf5 273 Pfam PF00005 ABC transporter 41 192 3.2E-35 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_15445 df756f997c65ca1907aba8f7557c8f25 304 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 6 303 8.3E-80 T 14-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 MB46_15445 df756f997c65ca1907aba8f7557c8f25 304 Pfam PF02569 Pantoate-beta-alanine ligase 6 301 3.2E-90 T 14-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 MB46_15445 df756f997c65ca1907aba8f7557c8f25 304 SUPERFAMILY SSF52374 24 303 3.38E-91 T 14-10-2018 MB46_15445 df756f997c65ca1907aba8f7557c8f25 304 Hamap MF_00158 Pantothenate synthetase [panC]. 4 303 38.566 T 14-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 MB46_15445 df756f997c65ca1907aba8f7557c8f25 304 Gene3D G3DSA:3.40.50.620 2 197 1.9E-69 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MB46_15445 df756f997c65ca1907aba8f7557c8f25 304 Gene3D G3DSA:3.30.1300.10 198 304 6.5E-30 T 14-10-2018 MB46_03045 ecafd2c6f0b07ec72493aac6ec25ba1d 502 Gene3D G3DSA:1.10.10.410 438 500 9.2E-15 T 14-10-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal MB46_03045 ecafd2c6f0b07ec72493aac6ec25ba1d 502 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 13 498 8.9E-138 T 14-10-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 MB46_03045 ecafd2c6f0b07ec72493aac6ec25ba1d 502 Gene3D G3DSA:1.10.150.380 321 436 6.2E-13 T 14-10-2018 MB46_03045 ecafd2c6f0b07ec72493aac6ec25ba1d 502 Pfam PF02637 GatB domain 351 498 1.6E-36 T 14-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 MB46_03045 ecafd2c6f0b07ec72493aac6ec25ba1d 502 Pfam PF02934 GatB/GatE catalytic domain 19 313 1.8E-101 T 14-10-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 MB46_03045 ecafd2c6f0b07ec72493aac6ec25ba1d 502 SMART SM00845 351 498 2.0E-52 T 14-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 MB46_03045 ecafd2c6f0b07ec72493aac6ec25ba1d 502 SUPERFAMILY SSF89095 350 498 1.96E-22 T 14-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 MB46_03045 ecafd2c6f0b07ec72493aac6ec25ba1d 502 SUPERFAMILY SSF55931 18 320 4.84E-107 T 14-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 MB46_03045 ecafd2c6f0b07ec72493aac6ec25ba1d 502 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 15 499 33.815 T 14-10-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 MB46_01300 08c3c1de006665c2ef13ae7eab8f9578 325 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 15 193 4.0E-48 T 14-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 MB46_01300 08c3c1de006665c2ef13ae7eab8f9578 325 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 195 291 1.0E-23 T 14-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 MB46_01300 08c3c1de006665c2ef13ae7eab8f9578 325 Gene3D G3DSA:1.10.1040.10 198 319 2.8E-33 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MB46_01300 08c3c1de006665c2ef13ae7eab8f9578 325 Gene3D G3DSA:3.40.50.720 2 197 6.7E-51 T 14-10-2018 MB46_01300 08c3c1de006665c2ef13ae7eab8f9578 325 SUPERFAMILY SSF48179 195 296 5.19E-23 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MB46_01300 08c3c1de006665c2ef13ae7eab8f9578 325 ProSitePatterns PS00067 3-hydroxyacyl-CoA dehydrogenase signature. 192 216 - T 14-10-2018 IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved site GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 MB46_01300 08c3c1de006665c2ef13ae7eab8f9578 325 PIRSF PIRSF000105 9 320 7.0E-76 T 14-10-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 MB46_01300 08c3c1de006665c2ef13ae7eab8f9578 325 SUPERFAMILY SSF51735 14 193 3.95E-43 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_07980 589e0ddab553fc6880c6bb757f964d7a 1110 TIGRFAM TIGR02868 CydC: thiol reductant ABC exporter, CydC subunit 567 1085 1.1E-130 T 14-10-2018 IPR014223 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC GO:0016021|GO:0034775|GO:0042626|GO:0045454 MB46_07980 589e0ddab553fc6880c6bb757f964d7a 1110 Pfam PF00005 ABC transporter 914 1056 2.6E-22 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_07980 589e0ddab553fc6880c6bb757f964d7a 1110 Gene3D G3DSA:1.20.1560.10 556 876 1.3E-14 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MB46_07980 589e0ddab553fc6880c6bb757f964d7a 1110 Gene3D G3DSA:1.20.1560.10 12 315 3.2E-24 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MB46_07980 589e0ddab553fc6880c6bb757f964d7a 1110 SUPERFAMILY SSF90123 565 872 4.05E-28 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MB46_07980 589e0ddab553fc6880c6bb757f964d7a 1110 SUPERFAMILY SSF52540 320 520 1.49E-28 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_07980 589e0ddab553fc6880c6bb757f964d7a 1110 Gene3D G3DSA:3.40.50.300 877 1108 6.6E-51 T 14-10-2018 MB46_07980 589e0ddab553fc6880c6bb757f964d7a 1110 SUPERFAMILY SSF52540 891 1099 3.78E-42 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_07980 589e0ddab553fc6880c6bb757f964d7a 1110 SMART SM00382 917 1101 5.8E-8 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_07980 589e0ddab553fc6880c6bb757f964d7a 1110 SMART SM00382 352 570 8.2E-5 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_07980 589e0ddab553fc6880c6bb757f964d7a 1110 Pfam PF00005 ABC transporter 346 487 5.9E-10 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_07980 589e0ddab553fc6880c6bb757f964d7a 1110 ProSitePatterns PS00211 ABC transporters family signature. 1028 1042 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_07980 589e0ddab553fc6880c6bb757f964d7a 1110 Gene3D G3DSA:3.40.50.300 324 527 1.8E-34 T 14-10-2018 MB46_07980 589e0ddab553fc6880c6bb757f964d7a 1110 Pfam PF00664 ABC transporter transmembrane region 116 267 1.1E-10 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 MB46_07980 589e0ddab553fc6880c6bb757f964d7a 1110 SUPERFAMILY SSF90123 11 319 1.96E-30 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MB46_07980 589e0ddab553fc6880c6bb757f964d7a 1110 ProSitePatterns PS00211 ABC transporters family signature. 454 468 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_11615 b5cd3d10381f5c9a1b093b47017da166 926 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 27 816 0.0 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MB46_11615 b5cd3d10381f5c9a1b093b47017da166 926 Pfam PF01043 SecA preprotein cross-linking domain 233 340 7.6E-36 T 14-10-2018 IPR011130 SecA, preprotein cross-linking domain GO:0016020|GO:0017038 MB46_11615 b5cd3d10381f5c9a1b093b47017da166 926 Hamap MF_01382 Protein translocase subunit SecA [secA]. 4 831 19.469 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MB46_11615 b5cd3d10381f5c9a1b093b47017da166 926 SUPERFAMILY SSF81767 231 350 1.57E-42 T 14-10-2018 IPR036670 SecA, preprotein cross-linking domain superfamily GO:0016020|GO:0017038 MB46_11615 b5cd3d10381f5c9a1b093b47017da166 926 ProSitePatterns PS01312 SecA family signature. 482 497 - T 14-10-2018 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 MB46_11615 b5cd3d10381f5c9a1b093b47017da166 926 SMART SM00957 5 384 5.9E-270 T 14-10-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 MB46_11615 b5cd3d10381f5c9a1b093b47017da166 926 SMART SM00958 228 340 1.4E-61 T 14-10-2018 IPR011130 SecA, preprotein cross-linking domain GO:0016020|GO:0017038 MB46_11615 b5cd3d10381f5c9a1b093b47017da166 926 Pfam PF07517 SecA DEAD-like domain 6 383 4.6E-124 T 14-10-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 MB46_11615 b5cd3d10381f5c9a1b093b47017da166 926 PRINTS PR00906 SecA protein signature 62 86 1.7E-69 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MB46_11615 b5cd3d10381f5c9a1b093b47017da166 926 PRINTS PR00906 SecA protein signature 358 375 1.7E-69 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MB46_11615 b5cd3d10381f5c9a1b093b47017da166 926 PRINTS PR00906 SecA protein signature 169 189 1.7E-69 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MB46_11615 b5cd3d10381f5c9a1b093b47017da166 926 PRINTS PR00906 SecA protein signature 100 114 1.7E-69 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MB46_11615 b5cd3d10381f5c9a1b093b47017da166 926 PRINTS PR00906 SecA protein signature 116 126 1.7E-69 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MB46_11615 b5cd3d10381f5c9a1b093b47017da166 926 PRINTS PR00906 SecA protein signature 395 408 1.7E-69 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MB46_11615 b5cd3d10381f5c9a1b093b47017da166 926 PRINTS PR00906 SecA protein signature 321 343 1.7E-69 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MB46_11615 b5cd3d10381f5c9a1b093b47017da166 926 Gene3D G3DSA:3.90.1440.10 228 350 7.2E-171 T 14-10-2018 MB46_11615 b5cd3d10381f5c9a1b093b47017da166 926 Gene3D G3DSA:3.40.50.300 399 616 1.6E-88 T 14-10-2018 MB46_11615 b5cd3d10381f5c9a1b093b47017da166 926 Gene3D G3DSA:1.10.3060.10 618 832 9.4E-73 T 14-10-2018 MB46_11615 b5cd3d10381f5c9a1b093b47017da166 926 Gene3D G3DSA:3.40.50.300 23 397 7.2E-171 T 14-10-2018 MB46_11615 b5cd3d10381f5c9a1b093b47017da166 926 SUPERFAMILY SSF52540 5 397 7.93E-75 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_11615 b5cd3d10381f5c9a1b093b47017da166 926 Pfam PF07516 SecA Wing and Scaffold domain 615 828 1.9E-63 T 14-10-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 MB46_11615 b5cd3d10381f5c9a1b093b47017da166 926 SUPERFAMILY SSF81886 617 839 5.89E-69 T 14-10-2018 IPR036266 SecA, Wing/Scaffold superfamily MB46_11615 b5cd3d10381f5c9a1b093b47017da166 926 SUPERFAMILY SSF52540 399 613 1.78E-57 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_18540 3ec39af0e82c3bb0a2286499d207bfbd 233 Pfam PF07987 Domain of unkown function (DUF1775) 30 176 1.7E-45 T 14-10-2018 IPR012533 YcnI-like MB46_18540 3ec39af0e82c3bb0a2286499d207bfbd 233 Gene3D G3DSA:2.60.40.2230 27 192 3.8E-36 T 14-10-2018 IPR038507 YcnI-like superfamily MB46_13260 b1cf2249a94f8d435f555aca9cc04300 171 Pfam PF00380 Ribosomal protein S9/S16 50 171 4.2E-42 T 14-10-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 MB46_13260 b1cf2249a94f8d435f555aca9cc04300 171 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 41 171 31.507 T 14-10-2018 IPR023035 Ribosomal protein S9, bacterial/plastid MB46_13260 b1cf2249a94f8d435f555aca9cc04300 171 SUPERFAMILY SSF54211 48 171 4.55E-41 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MB46_13260 b1cf2249a94f8d435f555aca9cc04300 171 ProSitePatterns PS00360 Ribosomal protein S9 signature. 109 127 - T 14-10-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 MB46_13260 b1cf2249a94f8d435f555aca9cc04300 171 Gene3D G3DSA:3.30.230.10 43 171 1.5E-46 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MB46_09955 db01333e5751149f076f67c038d233d1 538 Pfam PF01926 50S ribosome-binding GTPase 59 179 5.3E-8 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 MB46_09955 db01333e5751149f076f67c038d233d1 538 Gene3D G3DSA:3.40.50.300 38 260 1.6E-29 T 14-10-2018 MB46_09955 db01333e5751149f076f67c038d233d1 538 SUPERFAMILY SSF52540 51 247 5.68E-20 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_11935 3bedc6e6ff729406b419670a3416fd12 603 Pfam PF03600 Citrate transporter 9 190 1.1E-28 T 14-10-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 MB46_11935 3bedc6e6ff729406b419670a3416fd12 603 SUPERFAMILY SSF116726 216 293 9.42E-5 T 14-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 MB46_11935 3bedc6e6ff729406b419670a3416fd12 603 Pfam PF03600 Citrate transporter 423 598 2.4E-21 T 14-10-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 MB46_11935 3bedc6e6ff729406b419670a3416fd12 603 Gene3D G3DSA:3.30.70.1450 313 389 2.1E-5 T 14-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 MB46_11935 3bedc6e6ff729406b419670a3416fd12 603 SUPERFAMILY SSF116726 310 385 1.44E-6 T 14-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 MB46_15345 c8d31278a42071b51682f7eb52cce435 147 ProSitePatterns PS01117 MarR-type HTH domain signature. 70 105 - T 14-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site MB46_15345 c8d31278a42071b51682f7eb52cce435 147 Gene3D G3DSA:1.10.10.10 2 145 3.3E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_15345 c8d31278a42071b51682f7eb52cce435 147 SUPERFAMILY SSF46785 15 146 2.38E-24 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_15345 c8d31278a42071b51682f7eb52cce435 147 Pfam PF01047 MarR family 44 96 9.6E-12 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MB46_15345 c8d31278a42071b51682f7eb52cce435 147 SMART SM00347 32 132 7.4E-13 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MB46_15345 c8d31278a42071b51682f7eb52cce435 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 122 142 3.0E-7 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MB46_15345 c8d31278a42071b51682f7eb52cce435 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 92 108 3.0E-7 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MB46_15345 c8d31278a42071b51682f7eb52cce435 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 73 88 3.0E-7 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MB46_15345 c8d31278a42071b51682f7eb52cce435 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 56 72 3.0E-7 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MB46_16470 9984cef4dacb405fe09a8fe7ad94a4b9 493 SUPERFAMILY SSF48179 288 489 1.46E-53 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MB46_16470 9984cef4dacb405fe09a8fe7ad94a4b9 493 SUPERFAMILY SSF51735 5 287 1.34E-106 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_16470 9984cef4dacb405fe09a8fe7ad94a4b9 493 Gene3D G3DSA:1.10.1040.10 287 492 4.5E-61 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MB46_16470 9984cef4dacb405fe09a8fe7ad94a4b9 493 ProSitePatterns PS00974 Mannitol dehydrogenases signature. 223 235 - T 14-10-2018 IPR023027 Mannitol dehydrogenase, conserved site GO:0019594|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 MB46_16470 9984cef4dacb405fe09a8fe7ad94a4b9 493 Pfam PF08125 Mannitol dehydrogenase C-terminal domain 221 465 1.2E-68 T 14-10-2018 IPR013118 Mannitol dehydrogenase, C-terminal GO:0016491|GO:0050662|GO:0055114 MB46_16470 9984cef4dacb405fe09a8fe7ad94a4b9 493 PRINTS PR00084 Mannitol dehydrogenase signature 184 197 2.6E-21 T 14-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 MB46_16470 9984cef4dacb405fe09a8fe7ad94a4b9 493 PRINTS PR00084 Mannitol dehydrogenase signature 30 40 2.6E-21 T 14-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 MB46_16470 9984cef4dacb405fe09a8fe7ad94a4b9 493 PRINTS PR00084 Mannitol dehydrogenase signature 253 268 2.6E-21 T 14-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 MB46_16470 9984cef4dacb405fe09a8fe7ad94a4b9 493 PRINTS PR00084 Mannitol dehydrogenase signature 223 236 2.6E-21 T 14-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 MB46_16470 9984cef4dacb405fe09a8fe7ad94a4b9 493 Pfam PF01232 Mannitol dehydrogenase Rossmann domain 29 193 1.0E-46 T 14-10-2018 IPR013131 Mannitol dehydrogenase, N-terminal GO:0016491|GO:0055114 MB46_16470 9984cef4dacb405fe09a8fe7ad94a4b9 493 Gene3D G3DSA:3.40.50.720 2 286 2.4E-119 T 14-10-2018 MB46_14265 09143c3e9867c3390d0d62e82a982cee 470 Gene3D G3DSA:1.20.1250.20 268 461 2.4E-15 T 14-10-2018 MB46_14265 09143c3e9867c3390d0d62e82a982cee 470 Pfam PF07690 Major Facilitator Superfamily 2 287 4.2E-31 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MB46_14265 09143c3e9867c3390d0d62e82a982cee 470 Gene3D G3DSA:1.20.1720.10 1 189 7.7E-44 T 14-10-2018 MB46_14265 09143c3e9867c3390d0d62e82a982cee 470 SUPERFAMILY SSF103473 2 456 1.05E-52 T 14-10-2018 IPR036259 MFS transporter superfamily MB46_17370 e06afac8c9ddff2028ce9f62e1a4e291 658 SUPERFAMILY SSF56801 44 652 8.77E-175 T 14-10-2018 MB46_17370 e06afac8c9ddff2028ce9f62e1a4e291 658 Gene3D G3DSA:3.40.50.12780 71 528 4.9E-108 T 14-10-2018 MB46_17370 e06afac8c9ddff2028ce9f62e1a4e291 658 Pfam PF13193 AMP-binding enzyme C-terminal domain 544 622 3.2E-27 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain MB46_17370 e06afac8c9ddff2028ce9f62e1a4e291 658 Hamap MF_01123 Acetyl-coenzyme A synthetase [acs]. 21 656 50.181 T 14-10-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 MB46_17370 e06afac8c9ddff2028ce9f62e1a4e291 658 ProSitePatterns PS00455 Putative AMP-binding domain signature. 273 284 - T 14-10-2018 IPR020845 AMP-binding, conserved site MB46_17370 e06afac8c9ddff2028ce9f62e1a4e291 658 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 43 94 1.7E-17 T 14-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 MB46_17370 e06afac8c9ddff2028ce9f62e1a4e291 658 Gene3D G3DSA:3.30.300.30 531 658 8.9E-30 T 14-10-2018 MB46_17370 e06afac8c9ddff2028ce9f62e1a4e291 658 TIGRFAM TIGR02188 Ac_CoA_lig_AcsA: acetate--CoA ligase 39 654 1.2E-289 T 14-10-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 MB46_17370 e06afac8c9ddff2028ce9f62e1a4e291 658 Pfam PF00501 AMP-binding enzyme 101 535 2.1E-97 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 MB46_14200 8b4273449d9d60fb0ea8b58573f9ae75 380 Gene3D G3DSA:3.40.190.10 64 189 4.1E-17 T 14-10-2018 MB46_14200 8b4273449d9d60fb0ea8b58573f9ae75 380 Gene3D G3DSA:3.40.190.10 199 343 4.1E-18 T 14-10-2018 MB46_14200 8b4273449d9d60fb0ea8b58573f9ae75 380 TIGRFAM TIGR01728 SsuA_fam: ABC transporter, substrate-binding protein, aliphatic sulfonates family 68 317 8.8E-51 T 14-10-2018 IPR010067 Aliphatic sulfonates-binding protein GO:0016020|GO:0042626 MB46_14200 8b4273449d9d60fb0ea8b58573f9ae75 380 Pfam PF13379 NMT1-like family 65 298 4.7E-30 T 14-10-2018 MB46_14200 8b4273449d9d60fb0ea8b58573f9ae75 380 SUPERFAMILY SSF53850 66 297 9.2E-37 T 14-10-2018 MB46_00315 c09a28ff47a1dd643ec0bd2e2b876571 478 Pfam PF00083 Sugar (and other) transporter 24 462 2.0E-103 T 14-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 MB46_00315 c09a28ff47a1dd643ec0bd2e2b876571 478 Gene3D G3DSA:1.20.1250.20 16 466 2.0E-123 T 14-10-2018 MB46_00315 c09a28ff47a1dd643ec0bd2e2b876571 478 ProSitePatterns PS00217 Sugar transport proteins signature 2. 120 145 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MB46_00315 c09a28ff47a1dd643ec0bd2e2b876571 478 PRINTS PR00171 Sugar transporter signature 387 399 1.6E-23 T 14-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 MB46_00315 c09a28ff47a1dd643ec0bd2e2b876571 478 PRINTS PR00171 Sugar transporter signature 115 134 1.6E-23 T 14-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 MB46_00315 c09a28ff47a1dd643ec0bd2e2b876571 478 PRINTS PR00171 Sugar transporter signature 32 42 1.6E-23 T 14-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 MB46_00315 c09a28ff47a1dd643ec0bd2e2b876571 478 PRINTS PR00171 Sugar transporter signature 364 385 1.6E-23 T 14-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 MB46_00315 c09a28ff47a1dd643ec0bd2e2b876571 478 PRINTS PR00171 Sugar transporter signature 275 285 1.6E-23 T 14-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 MB46_00315 c09a28ff47a1dd643ec0bd2e2b876571 478 SUPERFAMILY SSF103473 18 460 1.44E-76 T 14-10-2018 IPR036259 MFS transporter superfamily MB46_00315 c09a28ff47a1dd643ec0bd2e2b876571 478 TIGRFAM TIGR00879 SP: MFS transporter, sugar porter (SP) family 21 458 2.8E-103 T 14-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 MB46_06465 aaa1cdde983a2a15ad684604fded7855 189 Pfam PF03551 Transcriptional regulator PadR-like family 3 64 6.3E-7 T 14-10-2018 IPR005149 Transcription regulator PadR, N-terminal MB46_06465 aaa1cdde983a2a15ad684604fded7855 189 SUPERFAMILY SSF46785 1 167 9.59E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_06465 aaa1cdde983a2a15ad684604fded7855 189 Gene3D G3DSA:1.10.10.10 1 73 2.3E-12 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_13225 ad204ca7d428aa21e83625607f1ace54 520 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 230 513 18.062 T 14-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 MB46_13225 ad204ca7d428aa21e83625607f1ace54 520 TIGRFAM TIGR00197 yjeF_nterm: YjeF family N-terminal domain 25 217 2.4E-26 T 14-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 MB46_13225 ad204ca7d428aa21e83625607f1ace54 520 ProSitePatterns PS01050 YjeF C-terminal domain signature 2. 439 449 - T 14-10-2018 IPR017953 Carbohydrate kinase, predicted, conserved site MB46_13225 ad204ca7d428aa21e83625607f1ace54 520 Hamap MF_01966 NAD(P)H-hydrate epimerase [nnrE]. 2 218 18.856 T 14-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 MB46_13225 ad204ca7d428aa21e83625607f1ace54 520 Pfam PF03853 YjeF-related protein N-terminus 25 197 1.1E-34 T 14-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 MB46_13225 ad204ca7d428aa21e83625607f1ace54 520 PIRSF PIRSF017184 2 509 1.4E-87 T 14-10-2018 IPR030677 Bifunctional NAD(P)H-hydrate repair enzyme Nnr GO:0052855 MetaCyc: PWY-6938 MB46_13225 ad204ca7d428aa21e83625607f1ace54 520 SUPERFAMILY SSF53613 228 485 1.53E-46 T 14-10-2018 IPR029056 Ribokinase-like MB46_13225 ad204ca7d428aa21e83625607f1ace54 520 Gene3D G3DSA:3.40.1190.20 224 511 3.9E-64 T 14-10-2018 IPR029056 Ribokinase-like MB46_13225 ad204ca7d428aa21e83625607f1ace54 520 SUPERFAMILY SSF64153 5 251 1.7E-42 T 14-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 MB46_13225 ad204ca7d428aa21e83625607f1ace54 520 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 238 457 3.9E-39 T 14-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 MB46_13225 ad204ca7d428aa21e83625607f1ace54 520 Pfam PF01256 Carbohydrate kinase 254 464 1.4E-41 T 14-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 MB46_13225 ad204ca7d428aa21e83625607f1ace54 520 Gene3D G3DSA:3.40.50.10260 3 221 9.9E-45 T 14-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 MB46_16450 6a19ec5bc4b7da3fd929c915dc0f60ab 311 SUPERFAMILY SSF161098 72 296 5.1E-57 T 14-10-2018 IPR035906 MetI-like superfamily MB46_16450 6a19ec5bc4b7da3fd929c915dc0f60ab 311 Gene3D G3DSA:1.10.3720.10 68 307 6.7E-63 T 14-10-2018 IPR035906 MetI-like superfamily MB46_16450 6a19ec5bc4b7da3fd929c915dc0f60ab 311 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 103 302 2.0E-14 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_00415 cbd49dfc1c207814492e897478c94744 265 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 208 249 - T 14-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 MB46_00415 cbd49dfc1c207814492e897478c94744 265 Pfam PF12833 Helix-turn-helix domain 177 252 1.1E-17 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MB46_00415 cbd49dfc1c207814492e897478c94744 265 Pfam PF02311 AraC-like ligand binding domain 33 100 6.2E-7 T 14-10-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 MB46_00415 cbd49dfc1c207814492e897478c94744 265 SUPERFAMILY SSF46689 207 252 2.51E-6 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MB46_00415 cbd49dfc1c207814492e897478c94744 265 SMART SM00342 171 253 1.5E-22 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MB46_00415 cbd49dfc1c207814492e897478c94744 265 Gene3D G3DSA:2.60.120.10 17 93 6.0E-6 T 14-10-2018 IPR014710 RmlC-like jelly roll fold MB46_00415 cbd49dfc1c207814492e897478c94744 265 Gene3D G3DSA:1.10.10.60 155 258 9.2E-19 T 14-10-2018 MB46_00415 cbd49dfc1c207814492e897478c94744 265 SUPERFAMILY SSF51182 13 187 8.45E-12 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily MB46_15705 272d6a34aea1dc5022a93de3d7c88b74 460 Gene3D G3DSA:3.50.50.60 6 460 3.4E-174 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_15705 272d6a34aea1dc5022a93de3d7c88b74 460 SUPERFAMILY SSF54373 299 404 3.53E-30 T 14-10-2018 MB46_15705 272d6a34aea1dc5022a93de3d7c88b74 460 Pfam PF01593 Flavin containing amine oxidoreductase 21 455 1.6E-70 T 14-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 MB46_15705 272d6a34aea1dc5022a93de3d7c88b74 460 SUPERFAMILY SSF51905 11 458 8.74E-63 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_15705 272d6a34aea1dc5022a93de3d7c88b74 460 PRINTS PR00757 Flavin-containing amine oxidase signature 12 31 9.2E-15 T 14-10-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 MB46_15705 272d6a34aea1dc5022a93de3d7c88b74 460 PRINTS PR00757 Flavin-containing amine oxidase signature 302 321 9.2E-15 T 14-10-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 MB46_15705 272d6a34aea1dc5022a93de3d7c88b74 460 PRINTS PR00757 Flavin-containing amine oxidase signature 385 404 9.2E-15 T 14-10-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 MB46_15705 272d6a34aea1dc5022a93de3d7c88b74 460 PRINTS PR00757 Flavin-containing amine oxidase signature 180 201 9.2E-15 T 14-10-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 MB46_15705 272d6a34aea1dc5022a93de3d7c88b74 460 PRINTS PR00757 Flavin-containing amine oxidase signature 437 454 9.2E-15 T 14-10-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 MB46_15705 272d6a34aea1dc5022a93de3d7c88b74 460 PRINTS PR00757 Flavin-containing amine oxidase signature 406 428 9.2E-15 T 14-10-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 MB46_09405 588dcaa1f82bb6892812844dd4f87156 352 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 35 146 7.3E-16 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MB46_09405 588dcaa1f82bb6892812844dd4f87156 352 SMART SM00829 20 347 0.0099 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MB46_09405 588dcaa1f82bb6892812844dd4f87156 352 Pfam PF00107 Zinc-binding dehydrogenase 189 310 5.7E-18 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 MB46_09405 588dcaa1f82bb6892812844dd4f87156 352 Gene3D G3DSA:3.90.180.10 18 336 3.8E-84 T 14-10-2018 MB46_09405 588dcaa1f82bb6892812844dd4f87156 352 SUPERFAMILY SSF51735 153 313 9.6E-30 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_09405 588dcaa1f82bb6892812844dd4f87156 352 SUPERFAMILY SSF50129 12 188 5.78E-38 T 14-10-2018 IPR011032 GroES-like superfamily MB46_09405 588dcaa1f82bb6892812844dd4f87156 352 Gene3D G3DSA:3.40.50.720 166 296 3.8E-84 T 14-10-2018 MB46_13905 cbd7ef6e1f0155f99d0f3c0bf141707c 133 Gene3D G3DSA:3.10.180.10 2 133 3.3E-35 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MB46_13905 cbd7ef6e1f0155f99d0f3c0bf141707c 133 SUPERFAMILY SSF54593 1 132 4.43E-27 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MB46_13905 cbd7ef6e1f0155f99d0f3c0bf141707c 133 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 128 3.1E-12 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MB46_12980 9b8f609a7be623081475376acf5e7a58 163 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 13 155 2.0E-26 T 14-10-2018 IPR002178 PTS EIIA type-2 domain MB46_12980 9b8f609a7be623081475376acf5e7a58 163 Gene3D G3DSA:3.40.930.10 10 156 3.3E-30 T 14-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 MB46_12980 9b8f609a7be623081475376acf5e7a58 163 SUPERFAMILY SSF55804 11 155 4.32E-28 T 14-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 MB46_16880 b9d272ef5e1807c8ec37a97bc65efd58 286 SUPERFAMILY SSF46785 2 110 9.09E-23 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_16880 b9d272ef5e1807c8ec37a97bc65efd58 286 Gene3D G3DSA:1.10.10.10 3 85 2.9E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_16880 b9d272ef5e1807c8ec37a97bc65efd58 286 Gene3D G3DSA:3.40.190.10 94 260 1.2E-49 T 14-10-2018 MB46_16880 b9d272ef5e1807c8ec37a97bc65efd58 286 Pfam PF03466 LysR substrate binding domain 88 274 6.1E-29 T 14-10-2018 IPR005119 LysR, substrate-binding MB46_16880 b9d272ef5e1807c8ec37a97bc65efd58 286 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 62 4.3E-22 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MB46_16880 b9d272ef5e1807c8ec37a97bc65efd58 286 SUPERFAMILY SSF53850 89 275 1.33E-26 T 14-10-2018 MB46_16880 b9d272ef5e1807c8ec37a97bc65efd58 286 Gene3D G3DSA:3.40.190.10 160 253 1.2E-49 T 14-10-2018 MB46_16880 b9d272ef5e1807c8ec37a97bc65efd58 286 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 1.1E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MB46_16880 b9d272ef5e1807c8ec37a97bc65efd58 286 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 1.1E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MB46_16880 b9d272ef5e1807c8ec37a97bc65efd58 286 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 1.1E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MB46_12840 dedef0060e8d3443bdff27849e2a647d 125 SUPERFAMILY SSF54593 5 120 4.43E-24 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MB46_12840 dedef0060e8d3443bdff27849e2a647d 125 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 115 2.2E-10 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MB46_12840 dedef0060e8d3443bdff27849e2a647d 125 Gene3D G3DSA:3.10.180.10 3 117 3.1E-29 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MB46_04150 9ebf55adaf628b73b06ecc11f86ef9f8 417 Pfam PF00202 Aminotransferase class-III 37 400 1.5E-107 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MB46_04150 9ebf55adaf628b73b06ecc11f86ef9f8 417 PIRSF PIRSF000521 38 142 7.4E-9 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MB46_04150 9ebf55adaf628b73b06ecc11f86ef9f8 417 PIRSF PIRSF000521 134 173 0.012 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MB46_04150 9ebf55adaf628b73b06ecc11f86ef9f8 417 PIRSF PIRSF000521 179 407 1.5E-31 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MB46_04150 9ebf55adaf628b73b06ecc11f86ef9f8 417 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 29 404 9.3E-133 T 14-10-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 MB46_04150 9ebf55adaf628b73b06ecc11f86ef9f8 417 Gene3D G3DSA:3.90.1150.10 37 397 1.2E-133 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MB46_04150 9ebf55adaf628b73b06ecc11f86ef9f8 417 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 233 270 - T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MB46_04150 9ebf55adaf628b73b06ecc11f86ef9f8 417 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 27 407 65.307 T 14-10-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 MB46_04150 9ebf55adaf628b73b06ecc11f86ef9f8 417 Gene3D G3DSA:3.40.640.10 71 316 1.2E-133 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MB46_04150 9ebf55adaf628b73b06ecc11f86ef9f8 417 SUPERFAMILY SSF53383 28 404 2.69E-117 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MB46_08490 8dda4286a8a5b3aa7c8eb361f968a7da 442 Hamap MF_00220_B Dihydroorotase [pyrC]. 6 429 41.604 T 14-10-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MB46_08490 8dda4286a8a5b3aa7c8eb361f968a7da 442 SUPERFAMILY SSF51556 56 371 1.72E-99 T 14-10-2018 IPR032466 Metal-dependent hydrolase MB46_08490 8dda4286a8a5b3aa7c8eb361f968a7da 442 Gene3D G3DSA:3.20.20.140 57 372 4.3E-127 T 14-10-2018 MB46_08490 8dda4286a8a5b3aa7c8eb361f968a7da 442 Pfam PF01979 Amidohydrolase family 53 424 7.2E-22 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 MB46_08490 8dda4286a8a5b3aa7c8eb361f968a7da 442 SUPERFAMILY SSF51338 7 439 7.93E-23 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 MB46_08490 8dda4286a8a5b3aa7c8eb361f968a7da 442 Gene3D G3DSA:2.30.40.10 17 424 4.3E-127 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 MB46_08490 8dda4286a8a5b3aa7c8eb361f968a7da 442 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 17 425 3.5E-127 T 14-10-2018 MB46_08490 8dda4286a8a5b3aa7c8eb361f968a7da 442 ProSitePatterns PS00483 Dihydroorotase signature 2. 306 317 - T 14-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MB46_03910 f2bc5065a48ef13abb94208e708f6f07 350 Hamap MF_00268 Protein RecA [recA]. 7 331 51.884 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 MB46_03910 f2bc5065a48ef13abb94208e708f6f07 350 Gene3D G3DSA:3.40.50.300 28 269 7.0E-81 T 14-10-2018 MB46_03910 f2bc5065a48ef13abb94208e708f6f07 350 ProSitePatterns PS00321 recA signature. 215 223 - T 14-10-2018 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 MB46_03910 f2bc5065a48ef13abb94208e708f6f07 350 PRINTS PR00142 RecA protein signature 95 124 1.5E-84 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 MB46_03910 f2bc5065a48ef13abb94208e708f6f07 350 PRINTS PR00142 RecA protein signature 129 158 1.5E-84 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 MB46_03910 f2bc5065a48ef13abb94208e708f6f07 350 PRINTS PR00142 RecA protein signature 212 240 1.5E-84 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 MB46_03910 f2bc5065a48ef13abb94208e708f6f07 350 PRINTS PR00142 RecA protein signature 299 316 1.5E-84 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 MB46_03910 f2bc5065a48ef13abb94208e708f6f07 350 PRINTS PR00142 RecA protein signature 167 196 1.5E-84 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 MB46_03910 f2bc5065a48ef13abb94208e708f6f07 350 PRINTS PR00142 RecA protein signature 245 274 1.5E-84 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 MB46_03910 f2bc5065a48ef13abb94208e708f6f07 350 SUPERFAMILY SSF54752 270 328 2.35E-19 T 14-10-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal MB46_03910 f2bc5065a48ef13abb94208e708f6f07 350 Gene3D G3DSA:3.30.250.10 270 348 5.1E-28 T 14-10-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal MB46_03910 f2bc5065a48ef13abb94208e708f6f07 350 SMART SM00382 59 230 4.2E-8 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_03910 f2bc5065a48ef13abb94208e708f6f07 350 SUPERFAMILY SSF52540 6 269 2.01E-65 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_03910 f2bc5065a48ef13abb94208e708f6f07 350 Pfam PF00154 recA bacterial DNA recombination protein 9 270 1.3E-141 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 MB46_03910 f2bc5065a48ef13abb94208e708f6f07 350 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 6 325 8.5E-170 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 MB46_02105 e15f8fb2376ae86d7c578f178ce7b783 719 SUPERFAMILY SSF48208 198 543 2.24E-36 T 14-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 MB46_02105 e15f8fb2376ae86d7c578f178ce7b783 719 SUPERFAMILY SSF52833 7 125 1.53E-23 T 14-10-2018 IPR036249 Thioredoxin-like superfamily MB46_02105 e15f8fb2376ae86d7c578f178ce7b783 719 Pfam PF03190 Protein of unknown function, DUF255 2 162 2.1E-69 T 14-10-2018 IPR004879 Domain of unknown function DUF255 MB46_02105 e15f8fb2376ae86d7c578f178ce7b783 719 Gene3D G3DSA:3.40.30.10 1 166 6.3E-63 T 14-10-2018 MB46_02105 e15f8fb2376ae86d7c578f178ce7b783 719 PIRSF PIRSF006402 1 719 2.3E-164 T 14-10-2018 IPR024705 Spermatogenesis-associated protein 20 MB46_14540 1225a3fb6d2ea92c1716180d4661a34b 333 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 47 9.4E-18 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MB46_14540 1225a3fb6d2ea92c1716180d4661a34b 333 Pfam PF13377 Periplasmic binding protein-like domain 167 329 3.9E-29 T 14-10-2018 MB46_14540 1225a3fb6d2ea92c1716180d4661a34b 333 Gene3D G3DSA:3.40.50.2300 91 321 1.3E-41 T 14-10-2018 MB46_14540 1225a3fb6d2ea92c1716180d4661a34b 333 Gene3D G3DSA:3.40.50.2300 159 326 1.3E-41 T 14-10-2018 MB46_14540 1225a3fb6d2ea92c1716180d4661a34b 333 SUPERFAMILY SSF53822 58 318 6.21E-34 T 14-10-2018 IPR028082 Periplasmic binding protein-like I MB46_14540 1225a3fb6d2ea92c1716180d4661a34b 333 SMART SM00354 1 71 9.0E-29 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MB46_14540 1225a3fb6d2ea92c1716180d4661a34b 333 SUPERFAMILY SSF47413 1 60 1.15E-17 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MB46_14540 1225a3fb6d2ea92c1716180d4661a34b 333 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 14-10-2018 MB46_14540 1225a3fb6d2ea92c1716180d4661a34b 333 Gene3D G3DSA:1.10.260.40 1 60 8.1E-22 T 14-10-2018 MB46_06865 35dcef5b654ddfbcbf1133527a996440 414 PIRSF PIRSF038800 4 414 6.5E-142 T 14-10-2018 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 MB46_06865 35dcef5b654ddfbcbf1133527a996440 414 Gene3D G3DSA:3.40.640.10 49 314 6.5E-131 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MB46_06865 35dcef5b654ddfbcbf1133527a996440 414 Pfam PF00266 Aminotransferase class-V 116 360 3.7E-22 T 14-10-2018 IPR000192 Aminotransferase class V domain MB46_06865 35dcef5b654ddfbcbf1133527a996440 414 SUPERFAMILY SSF53383 13 411 1.16E-75 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MB46_06865 35dcef5b654ddfbcbf1133527a996440 414 Gene3D G3DSA:3.90.1150.10 15 410 6.5E-131 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MB46_01550 09574ed4afbbe49687517c2d6c807586 147 PIRSF PIRSF008546 1 140 2.1E-53 T 14-10-2018 IPR014937 Protein of unknown function DUF1810 MB46_01550 09574ed4afbbe49687517c2d6c807586 147 Pfam PF08837 Protein of unknown function (DUF1810) 3 137 3.0E-52 T 14-10-2018 IPR014937 Protein of unknown function DUF1810 MB46_01550 09574ed4afbbe49687517c2d6c807586 147 SUPERFAMILY SSF140736 3 137 3.79E-54 T 14-10-2018 IPR036287 Rv1873-like superfamily MB46_01550 09574ed4afbbe49687517c2d6c807586 147 Gene3D G3DSA:1.25.40.380 1 140 5.0E-51 T 14-10-2018 IPR036287 Rv1873-like superfamily MB46_16660 d79c90e946dcb0b75a7586fe36c49014 931 Pfam PF13183 4Fe-4S dicluster domain 525 598 1.3E-8 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MB46_16660 d79c90e946dcb0b75a7586fe36c49014 931 Gene3D G3DSA:3.40.462.40 253 300 2.8E-5 T 14-10-2018 MB46_16660 d79c90e946dcb0b75a7586fe36c49014 931 SUPERFAMILY SSF56176 7 251 3.74E-52 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 MB46_16660 d79c90e946dcb0b75a7586fe36c49014 931 SUPERFAMILY SSF55103 227 505 3.6E-48 T 14-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 MB46_16660 d79c90e946dcb0b75a7586fe36c49014 931 Pfam PF02913 FAD linked oxidases, C-terminal domain 255 500 3.2E-51 T 14-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 MB46_16660 d79c90e946dcb0b75a7586fe36c49014 931 Gene3D G3DSA:1.10.1060.10 512 617 6.4E-7 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 MB46_16660 d79c90e946dcb0b75a7586fe36c49014 931 Pfam PF01565 FAD binding domain 28 164 9.8E-34 T 14-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 MB46_16660 d79c90e946dcb0b75a7586fe36c49014 931 Gene3D G3DSA:1.10.45.10 470 502 6.7E-6 T 14-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 MB46_16660 d79c90e946dcb0b75a7586fe36c49014 931 Pfam PF02754 Cysteine-rich domain 691 780 0.06 T 14-10-2018 IPR004017 Cysteine-rich domain MB46_16660 d79c90e946dcb0b75a7586fe36c49014 931 Pfam PF02754 Cysteine-rich domain 827 905 8.7E-4 T 14-10-2018 IPR004017 Cysteine-rich domain MB46_16660 d79c90e946dcb0b75a7586fe36c49014 931 Gene3D G3DSA:3.30.70.2740 380 462 2.3E-8 T 14-10-2018 MB46_16660 d79c90e946dcb0b75a7586fe36c49014 931 SUPERFAMILY SSF46548 478 611 1.66E-19 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 MB46_16660 d79c90e946dcb0b75a7586fe36c49014 931 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 528 539 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MB46_16660 d79c90e946dcb0b75a7586fe36c49014 931 Gene3D G3DSA:3.30.465.40 228 252 2.8E-5 T 14-10-2018 MB46_16660 d79c90e946dcb0b75a7586fe36c49014 931 Gene3D G3DSA:3.30.465.40 5 183 1.9E-35 T 14-10-2018 MB46_03650 06bdff18e1dcfceeafe67b8096ace6b2 468 Gene3D G3DSA:2.115.10.20 1 309 2.6E-115 T 14-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily MB46_03650 06bdff18e1dcfceeafe67b8096ace6b2 468 SMART SM00640 1 425 1.5E-92 T 14-10-2018 IPR001362 Glycoside hydrolase, family 32 GO:0004553|GO:0005975 MB46_03650 06bdff18e1dcfceeafe67b8096ace6b2 468 SUPERFAMILY SSF49899 300 461 9.5E-16 T 14-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily MB46_03650 06bdff18e1dcfceeafe67b8096ace6b2 468 Pfam PF00251 Glycosyl hydrolases family 32 N-terminal domain 1 300 1.0E-69 T 14-10-2018 IPR013148 Glycosyl hydrolase family 32, N-terminal MB46_03650 06bdff18e1dcfceeafe67b8096ace6b2 468 Gene3D G3DSA:2.60.120.560 310 452 2.6E-115 T 14-10-2018 MB46_03650 06bdff18e1dcfceeafe67b8096ace6b2 468 Pfam PF08244 Glycosyl hydrolases family 32 C terminal 307 447 5.9E-10 T 14-10-2018 IPR013189 Glycosyl hydrolase family 32, C-terminal MB46_03650 06bdff18e1dcfceeafe67b8096ace6b2 468 SUPERFAMILY SSF75005 1 301 5.34E-74 T 14-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily MB46_08800 3e186359e6b7ca7db01966ea22c8f091 325 PIRSF PIRSF000355 2 322 3.5E-81 T 14-10-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MB46_08800 3e186359e6b7ca7db01966ea22c8f091 325 SUPERFAMILY SSF47240 8 325 6.87E-108 T 14-10-2018 IPR009078 Ferritin-like superfamily MB46_08800 3e186359e6b7ca7db01966ea22c8f091 325 TIGRFAM TIGR04171 RNR_1b_NrdF: ribonucleoside-diphosphate reductase, class 1b, beta subunit 13 325 1.4E-146 T 14-10-2018 IPR026494 Ribonucleoside reductase subunit beta, NrdF GO:0005971|GO:0009263 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MB46_08800 3e186359e6b7ca7db01966ea22c8f091 325 Gene3D G3DSA:1.10.620.20 3 297 9.4E-116 T 14-10-2018 IPR012348 Ribonucleotide reductase-like GO:0016491|GO:0055114 Reactome: R-HSA-499943 MB46_08800 3e186359e6b7ca7db01966ea22c8f091 325 ProSitePatterns PS00368 Ribonucleotide reductase small subunit signature. 103 119 - T 14-10-2018 IPR030475 Ribonucleotide reductase small subunit, acitve site KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MB46_08800 3e186359e6b7ca7db01966ea22c8f091 325 Pfam PF00268 Ribonucleotide reductase, small chain 15 286 7.0E-91 T 14-10-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MB46_13410 116edc573da491b9238d739dd719e990 121 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 1 115 28.807 T 14-10-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_13410 116edc573da491b9238d739dd719e990 121 Pfam PF00237 Ribosomal protein L22p/L17e 5 112 3.4E-34 T 14-10-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 MB46_13410 116edc573da491b9238d739dd719e990 121 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 5 112 2.8E-41 T 14-10-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_13410 116edc573da491b9238d739dd719e990 121 ProSitePatterns PS00464 Ribosomal protein L22 signature. 88 112 - T 14-10-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MB46_13410 116edc573da491b9238d739dd719e990 121 Gene3D G3DSA:3.90.470.10 1 121 9.9E-46 T 14-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 MB46_13410 116edc573da491b9238d739dd719e990 121 SUPERFAMILY SSF54843 1 114 5.1E-39 T 14-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 MB46_13155 63de9989e624480c26280592c98e6e7e 398 SMART SM01005 257 394 2.2E-56 T 14-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MB46_13155 63de9989e624480c26280592c98e6e7e 398 Hamap MF_01201 Alanine racemase. 15 394 31.821 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MB46_13155 63de9989e624480c26280592c98e6e7e 398 SUPERFAMILY SSF50621 252 395 6.98E-40 T 14-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 MB46_13155 63de9989e624480c26280592c98e6e7e 398 Pfam PF00842 Alanine racemase, C-terminal domain 257 393 1.1E-39 T 14-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MB46_13155 63de9989e624480c26280592c98e6e7e 398 PRINTS PR00992 Alanine racemase signature 290 305 1.3E-56 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MB46_13155 63de9989e624480c26280592c98e6e7e 398 PRINTS PR00992 Alanine racemase signature 40 56 1.3E-56 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MB46_13155 63de9989e624480c26280592c98e6e7e 398 PRINTS PR00992 Alanine racemase signature 173 184 1.3E-56 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MB46_13155 63de9989e624480c26280592c98e6e7e 398 PRINTS PR00992 Alanine racemase signature 76 94 1.3E-56 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MB46_13155 63de9989e624480c26280592c98e6e7e 398 PRINTS PR00992 Alanine racemase signature 136 148 1.3E-56 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MB46_13155 63de9989e624480c26280592c98e6e7e 398 PRINTS PR00992 Alanine racemase signature 273 288 1.3E-56 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MB46_13155 63de9989e624480c26280592c98e6e7e 398 PRINTS PR00992 Alanine racemase signature 310 327 1.3E-56 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MB46_13155 63de9989e624480c26280592c98e6e7e 398 PRINTS PR00992 Alanine racemase signature 216 243 1.3E-56 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MB46_13155 63de9989e624480c26280592c98e6e7e 398 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 45 55 - T 14-10-2018 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MB46_13155 63de9989e624480c26280592c98e6e7e 398 Gene3D G3DSA:3.20.20.10 24 238 1.1E-120 T 14-10-2018 IPR029066 PLP-binding barrel MB46_13155 63de9989e624480c26280592c98e6e7e 398 TIGRFAM TIGR00492 alr: alanine racemase 19 394 2.2E-94 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MB46_13155 63de9989e624480c26280592c98e6e7e 398 Gene3D G3DSA:2.40.37.10 22 393 1.1E-120 T 14-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 MB46_13155 63de9989e624480c26280592c98e6e7e 398 SUPERFAMILY SSF51419 22 258 3.34E-64 T 14-10-2018 IPR029066 PLP-binding barrel MB46_13155 63de9989e624480c26280592c98e6e7e 398 Pfam PF01168 Alanine racemase, N-terminal domain 22 243 3.8E-66 T 14-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MB46_06780 fb8a2a9ad1aa02b52787587899c85ae4 270 Pfam PF00106 short chain dehydrogenase 10 197 5.7E-42 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_06780 fb8a2a9ad1aa02b52787587899c85ae4 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 6.1E-19 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_06780 fb8a2a9ad1aa02b52787587899c85ae4 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 6.1E-19 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_06780 fb8a2a9ad1aa02b52787587899c85ae4 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 6.1E-19 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_06780 fb8a2a9ad1aa02b52787587899c85ae4 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 6.1E-19 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_06780 fb8a2a9ad1aa02b52787587899c85ae4 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 6.1E-19 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_06780 fb8a2a9ad1aa02b52787587899c85ae4 270 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 187 0.0068 T 14-10-2018 MB46_06780 fb8a2a9ad1aa02b52787587899c85ae4 270 SUPERFAMILY SSF51735 1 249 2.58E-53 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_06780 fb8a2a9ad1aa02b52787587899c85ae4 270 Gene3D G3DSA:3.40.50.720 8 258 1.2E-55 T 14-10-2018 MB46_06780 fb8a2a9ad1aa02b52787587899c85ae4 270 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 1.7E-5 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_06780 fb8a2a9ad1aa02b52787587899c85ae4 270 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 1.7E-5 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_06780 fb8a2a9ad1aa02b52787587899c85ae4 270 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 1.7E-5 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_06780 fb8a2a9ad1aa02b52787587899c85ae4 270 PIRSF PIRSF000126 2 267 1.3E-66 T 14-10-2018 MB46_03100 aa1a2a3a6bb7df2fb08ff8b49de6f10c 402 Hamap MF_00985 2-amino-3-ketobutyrate coenzyme A ligase [kbl]. 2 402 51.984 T 14-10-2018 IPR011282 2-amino-3-ketobutyrate coenzyme A ligase GO:0006567|GO:0008890 KEGG: 00260+2.3.1.29|Reactome: R-HSA-8849175 MB46_03100 aa1a2a3a6bb7df2fb08ff8b49de6f10c 402 Pfam PF00155 Aminotransferase class I and II 47 394 4.4E-67 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MB46_03100 aa1a2a3a6bb7df2fb08ff8b49de6f10c 402 TIGRFAM TIGR01822 2am3keto_CoA: glycine C-acetyltransferase 5 397 7.5E-183 T 14-10-2018 IPR011282 2-amino-3-ketobutyrate coenzyme A ligase GO:0006567|GO:0008890 KEGG: 00260+2.3.1.29|Reactome: R-HSA-8849175 MB46_03100 aa1a2a3a6bb7df2fb08ff8b49de6f10c 402 Gene3D G3DSA:3.90.1150.10 47 395 5.0E-131 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MB46_03100 aa1a2a3a6bb7df2fb08ff8b49de6f10c 402 SUPERFAMILY SSF53383 6 398 2.53E-110 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MB46_03100 aa1a2a3a6bb7df2fb08ff8b49de6f10c 402 Gene3D G3DSA:3.40.640.10 62 304 5.0E-131 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MB46_03100 aa1a2a3a6bb7df2fb08ff8b49de6f10c 402 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 249 258 - T 14-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 MB46_07255 1c457e8e38e22194a4d6f775bd17f586 846 ProSitePatterns PS00211 ABC transporters family signature. 369 383 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_07255 1c457e8e38e22194a4d6f775bd17f586 846 Gene3D G3DSA:1.10.8.280 167 281 1.3E-173 T 14-10-2018 MB46_07255 1c457e8e38e22194a4d6f775bd17f586 846 SUPERFAMILY SSF52540 23 451 8.38E-29 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_07255 1c457e8e38e22194a4d6f775bd17f586 846 Gene3D G3DSA:3.40.50.300 504 840 1.6E-123 T 14-10-2018 MB46_07255 1c457e8e38e22194a4d6f775bd17f586 846 Gene3D G3DSA:3.40.50.300 23 470 1.3E-173 T 14-10-2018 MB46_07255 1c457e8e38e22194a4d6f775bd17f586 846 Pfam PF00005 ABC transporter 511 764 4.9E-10 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_07255 1c457e8e38e22194a4d6f775bd17f586 846 Gene3D G3DSA:1.20.1580.10 109 369 1.3E-173 T 14-10-2018 MB46_07255 1c457e8e38e22194a4d6f775bd17f586 846 Gene3D G3DSA:1.20.1580.10 618 775 1.6E-123 T 14-10-2018 MB46_07255 1c457e8e38e22194a4d6f775bd17f586 846 SUPERFAMILY SSF52540 508 814 3.49E-45 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_07255 1c457e8e38e22194a4d6f775bd17f586 846 SMART SM00382 41 505 16.0 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_07255 1c457e8e38e22194a4d6f775bd17f586 846 SMART SM00382 520 812 0.0058 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_07255 1c457e8e38e22194a4d6f775bd17f586 846 ProSitePatterns PS00211 ABC transporters family signature. 734 748 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_02160 535ac01d21bcf15f38c37223997e1cbc 220 SMART SM00448 5 113 9.5E-21 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MB46_02160 535ac01d21bcf15f38c37223997e1cbc 220 SUPERFAMILY SSF52172 4 132 1.22E-27 T 14-10-2018 IPR011006 CheY-like superfamily MB46_02160 535ac01d21bcf15f38c37223997e1cbc 220 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 155 201 3.0E-7 T 14-10-2018 IPR002831 Transcription regulator TrmB, N-terminal MB46_02160 535ac01d21bcf15f38c37223997e1cbc 220 Pfam PF00072 Response regulator receiver domain 7 113 5.2E-15 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MB46_02160 535ac01d21bcf15f38c37223997e1cbc 220 SUPERFAMILY SSF46785 154 219 2.03E-7 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_02160 535ac01d21bcf15f38c37223997e1cbc 220 Gene3D G3DSA:3.40.50.2300 2 139 1.6E-21 T 14-10-2018 MB46_02160 535ac01d21bcf15f38c37223997e1cbc 220 Gene3D G3DSA:1.10.10.10 152 220 5.7E-6 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_02160 535ac01d21bcf15f38c37223997e1cbc 220 PIRSF PIRSF006171 3 220 2.0E-61 T 14-10-2018 IPR024187 Signal transduction response regulator, citrate/malate metabolism GO:0000160|GO:0003700 MB46_05995 4912da445eb5775cbf433f8f9cb382aa 440 SUPERFAMILY SSF53850 43 430 1.28E-44 T 14-10-2018 MB46_05995 4912da445eb5775cbf433f8f9cb382aa 440 Pfam PF13416 Bacterial extracellular solute-binding protein 60 327 1.0E-15 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein MB46_05995 4912da445eb5775cbf433f8f9cb382aa 440 Gene3D G3DSA:3.40.190.10 30 434 1.1E-49 T 14-10-2018 MB46_19970 31d22e0b7021a51de327f1457cc538b7 324 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 6 315 1.6E-95 T 14-10-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 MB46_19970 31d22e0b7021a51de327f1457cc538b7 324 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 228 315 6.5E-26 T 14-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 MB46_19970 31d22e0b7021a51de327f1457cc538b7 324 SUPERFAMILY SSF53901 8 315 2.08E-55 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 MB46_19970 31d22e0b7021a51de327f1457cc538b7 324 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 107 187 7.7E-27 T 14-10-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 MB46_19970 31d22e0b7021a51de327f1457cc538b7 324 Gene3D G3DSA:3.40.47.10 3 322 5.3E-104 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 MB46_19970 31d22e0b7021a51de327f1457cc538b7 324 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 4 315 58.382 T 14-10-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 MB46_19170 31d22e0b7021a51de327f1457cc538b7 324 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 6 315 1.6E-95 T 14-10-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 MB46_19170 31d22e0b7021a51de327f1457cc538b7 324 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 228 315 6.5E-26 T 14-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 MB46_19170 31d22e0b7021a51de327f1457cc538b7 324 SUPERFAMILY SSF53901 8 315 2.08E-55 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 MB46_19170 31d22e0b7021a51de327f1457cc538b7 324 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 107 187 7.7E-27 T 14-10-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 MB46_19170 31d22e0b7021a51de327f1457cc538b7 324 Gene3D G3DSA:3.40.47.10 3 322 5.3E-104 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 MB46_19170 31d22e0b7021a51de327f1457cc538b7 324 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 4 315 58.382 T 14-10-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 MB46_05560 de9220375e54ef88f5239d3614f1739f 221 Gene3D G3DSA:1.20.120.450 3 63 5.0E-9 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes MB46_05560 de9220375e54ef88f5239d3614f1739f 221 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 17 56 7.8E-8 T 14-10-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 MB46_05560 de9220375e54ef88f5239d3614f1739f 221 SUPERFAMILY SSF109854 4 130 2.2E-14 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes MB46_05560 de9220375e54ef88f5239d3614f1739f 221 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 14 193 8.8E-25 T 14-10-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type MB46_08760 140caae5d421cc5dd1400e1ded13493e 362 TIGRFAM TIGR03451 mycoS_dep_FDH: S-(hydroxymethyl)mycothiol dehydrogenase 5 361 4.0E-198 T 14-10-2018 IPR017816 S-(hydroxymethyl)mycothiol dehydrogenase MetaCyc: PWY-7908 MB46_08760 140caae5d421cc5dd1400e1ded13493e 362 SUPERFAMILY SSF50129 2 186 4.26E-51 T 14-10-2018 IPR011032 GroES-like superfamily MB46_08760 140caae5d421cc5dd1400e1ded13493e 362 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 14-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 MB46_08760 140caae5d421cc5dd1400e1ded13493e 362 Gene3D G3DSA:3.40.50.720 167 304 1.4E-110 T 14-10-2018 MB46_08760 140caae5d421cc5dd1400e1ded13493e 362 Pfam PF00107 Zinc-binding dehydrogenase 190 316 8.5E-28 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 MB46_08760 140caae5d421cc5dd1400e1ded13493e 362 SMART SM00829 17 359 0.0017 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MB46_08760 140caae5d421cc5dd1400e1ded13493e 362 SUPERFAMILY SSF51735 152 326 4.96E-42 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_08760 140caae5d421cc5dd1400e1ded13493e 362 Gene3D G3DSA:3.90.180.10 10 358 1.4E-110 T 14-10-2018 MB46_08760 140caae5d421cc5dd1400e1ded13493e 362 SUPERFAMILY SSF50129 310 361 8.0E-7 T 14-10-2018 IPR011032 GroES-like superfamily MB46_08760 140caae5d421cc5dd1400e1ded13493e 362 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 147 2.1E-24 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MB46_11880 d5b7321b1fd5fa43cb2ab5dc8c791078 378 SUPERFAMILY SSF56645 4 239 3.66E-77 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 MB46_11880 d5b7321b1fd5fa43cb2ab5dc8c791078 378 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 5 114 4.1E-29 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MB46_11880 d5b7321b1fd5fa43cb2ab5dc8c791078 378 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 226 373 3.3E-46 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MB46_11880 d5b7321b1fd5fa43cb2ab5dc8c791078 378 SUPERFAMILY SSF47203 224 375 1.61E-52 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 MB46_11880 d5b7321b1fd5fa43cb2ab5dc8c791078 378 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 120 214 4.6E-25 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MB46_11880 d5b7321b1fd5fa43cb2ab5dc8c791078 378 Gene3D G3DSA:1.10.540.10 2 116 1.9E-34 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 MB46_11880 d5b7321b1fd5fa43cb2ab5dc8c791078 378 PIRSF PIRSF016578 206 369 1.6E-7 T 14-10-2018 MB46_11880 d5b7321b1fd5fa43cb2ab5dc8c791078 378 PIRSF PIRSF016578 1 191 2.8E-10 T 14-10-2018 MB46_11880 d5b7321b1fd5fa43cb2ab5dc8c791078 378 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 334 353 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 MB46_11880 d5b7321b1fd5fa43cb2ab5dc8c791078 378 Gene3D G3DSA:1.20.140.10 230 376 1.6E-49 T 14-10-2018 MB46_11880 d5b7321b1fd5fa43cb2ab5dc8c791078 378 Gene3D G3DSA:2.40.110.10 119 229 6.2E-40 T 14-10-2018 MB46_08165 1ed860268c70f484be8478409c89fba3 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 4.8E-39 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_08165 1ed860268c70f484be8478409c89fba3 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 4.8E-39 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_08165 1ed860268c70f484be8478409c89fba3 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 4.8E-39 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_08165 1ed860268c70f484be8478409c89fba3 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 4.8E-39 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_08165 1ed860268c70f484be8478409c89fba3 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 4.8E-39 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_08165 1ed860268c70f484be8478409c89fba3 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 4.8E-39 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_08165 1ed860268c70f484be8478409c89fba3 251 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 250 2.7E-54 T 14-10-2018 MB46_08165 1ed860268c70f484be8478409c89fba3 251 Gene3D G3DSA:3.40.50.720 1 251 3.9E-72 T 14-10-2018 MB46_08165 1ed860268c70f484be8478409c89fba3 251 SUPERFAMILY SSF51735 4 250 1.03E-70 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_08165 1ed860268c70f484be8478409c89fba3 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 147 4.7E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_08165 1ed860268c70f484be8478409c89fba3 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 160 179 4.7E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_08165 1ed860268c70f484be8478409c89fba3 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 4.7E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_05480 5cc54b50d3bc77867ba0f59118efb596 161 Pfam PF01957 NfeD-like C-terminal, partner-binding 12 146 4.1E-14 T 14-10-2018 IPR002810 NfeD-like, C-terminal domain MB46_05480 5cc54b50d3bc77867ba0f59118efb596 161 Gene3D G3DSA:2.40.50.140 89 147 3.0E-16 T 14-10-2018 MB46_05480 5cc54b50d3bc77867ba0f59118efb596 161 SUPERFAMILY SSF141322 86 146 8.24E-6 T 14-10-2018 MB46_04545 27e98a6eaf9f097f0d7c65ca281935c0 249 SUPERFAMILY SSF81338 6 241 2.75E-58 T 14-10-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 MB46_04545 27e98a6eaf9f097f0d7c65ca281935c0 249 PRINTS PR00783 Major intrinsic protein family signature 5 24 7.1E-29 T 14-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 MB46_04545 27e98a6eaf9f097f0d7c65ca281935c0 249 PRINTS PR00783 Major intrinsic protein family signature 146 164 7.1E-29 T 14-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 MB46_04545 27e98a6eaf9f097f0d7c65ca281935c0 249 PRINTS PR00783 Major intrinsic protein family signature 174 196 7.1E-29 T 14-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 MB46_04545 27e98a6eaf9f097f0d7c65ca281935c0 249 PRINTS PR00783 Major intrinsic protein family signature 46 70 7.1E-29 T 14-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 MB46_04545 27e98a6eaf9f097f0d7c65ca281935c0 249 PRINTS PR00783 Major intrinsic protein family signature 221 241 7.1E-29 T 14-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 MB46_04545 27e98a6eaf9f097f0d7c65ca281935c0 249 Pfam PF00230 Major intrinsic protein 7 237 9.8E-36 T 14-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 MB46_04545 27e98a6eaf9f097f0d7c65ca281935c0 249 ProSitePatterns PS00221 MIP family signature. 64 72 - T 14-10-2018 IPR022357 Major intrinsic protein, conserved site Reactome: R-HSA-432047 MB46_04545 27e98a6eaf9f097f0d7c65ca281935c0 249 Gene3D G3DSA:1.20.1080.10 4 245 1.9E-65 T 14-10-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 MB46_01330 4ed719bef77b57a9a295829b85f1eba6 279 Gene3D G3DSA:3.40.50.720 2 274 3.4E-66 T 14-10-2018 MB46_01330 4ed719bef77b57a9a295829b85f1eba6 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 1.2E-14 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_01330 4ed719bef77b57a9a295829b85f1eba6 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 73 84 1.2E-14 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_01330 4ed719bef77b57a9a295829b85f1eba6 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 117 133 1.2E-14 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_01330 4ed719bef77b57a9a295829b85f1eba6 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 1.2E-14 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_01330 4ed719bef77b57a9a295829b85f1eba6 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 1.2E-14 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_01330 4ed719bef77b57a9a295829b85f1eba6 279 Pfam PF00106 short chain dehydrogenase 4 196 5.7E-31 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_01330 4ed719bef77b57a9a295829b85f1eba6 279 SUPERFAMILY SSF51735 2 245 5.37E-50 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_09620 61d7b736f88489342186aff5f9115e42 464 SUPERFAMILY SSF51735 3 180 3.15E-31 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_09620 61d7b736f88489342186aff5f9115e42 464 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 319 345 1.9E-37 T 14-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MB46_09620 61d7b736f88489342186aff5f9115e42 464 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 134 147 1.9E-37 T 14-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MB46_09620 61d7b736f88489342186aff5f9115e42 464 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 210 227 1.9E-37 T 14-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MB46_09620 61d7b736f88489342186aff5f9115e42 464 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 228 244 1.9E-37 T 14-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MB46_09620 61d7b736f88489342186aff5f9115e42 464 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 158 186 1.9E-37 T 14-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MB46_09620 61d7b736f88489342186aff5f9115e42 464 Gene3D G3DSA:3.40.50.720 4 420 5.7E-119 T 14-10-2018 MB46_09620 61d7b736f88489342186aff5f9115e42 464 SUPERFAMILY SSF55347 168 459 1.24E-77 T 14-10-2018 MB46_09620 61d7b736f88489342186aff5f9115e42 464 Gene3D G3DSA:3.30.360.10 168 458 5.7E-119 T 14-10-2018 MB46_09620 61d7b736f88489342186aff5f9115e42 464 PIRSF PIRSF000110 1 463 6.3E-111 T 14-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MB46_09620 61d7b736f88489342186aff5f9115e42 464 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 5 178 8.1E-32 T 14-10-2018 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MB46_09620 61d7b736f88489342186aff5f9115e42 464 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 1 461 61.282 T 14-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MB46_09620 61d7b736f88489342186aff5f9115e42 464 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 181 458 1.1E-68 T 14-10-2018 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MB46_07840 cb0e3296d48df5fc731bf3d2b35faf02 452 Pfam PF01612 3'-5' exonuclease 57 219 4.7E-29 T 14-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 MB46_07840 cb0e3296d48df5fc731bf3d2b35faf02 452 SMART SM00474 54 220 1.3E-34 T 14-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 MB46_07840 cb0e3296d48df5fc731bf3d2b35faf02 452 SMART SM00341 259 339 2.6E-17 T 14-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 MB46_07840 cb0e3296d48df5fc731bf3d2b35faf02 452 Gene3D G3DSA:1.10.150.80 244 339 6.8E-24 T 14-10-2018 MB46_07840 cb0e3296d48df5fc731bf3d2b35faf02 452 Gene3D G3DSA:1.10.150.80 346 437 1.8E-26 T 14-10-2018 MB46_07840 cb0e3296d48df5fc731bf3d2b35faf02 452 Pfam PF00570 HRDC domain 262 329 4.2E-13 T 14-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 MB46_07840 cb0e3296d48df5fc731bf3d2b35faf02 452 SUPERFAMILY SSF47819 246 335 1.7E-20 T 14-10-2018 IPR010997 HRDC-like superfamily GO:0000166|GO:0003824|GO:0044237 MB46_07840 cb0e3296d48df5fc731bf3d2b35faf02 452 Gene3D G3DSA:3.30.420.10 40 242 1.0E-67 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 MB46_07840 cb0e3296d48df5fc731bf3d2b35faf02 452 SUPERFAMILY SSF53098 54 255 7.21E-47 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily MB46_05705 32f3592b1b1d62176dea81dbb7098549 295 PRINTS PR00690 Adhesin family signature 177 198 2.9E-38 T 14-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 MB46_05705 32f3592b1b1d62176dea81dbb7098549 295 PRINTS PR00690 Adhesin family signature 67 84 2.9E-38 T 14-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 MB46_05705 32f3592b1b1d62176dea81dbb7098549 295 PRINTS PR00690 Adhesin family signature 230 248 2.9E-38 T 14-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 MB46_05705 32f3592b1b1d62176dea81dbb7098549 295 PRINTS PR00690 Adhesin family signature 54 67 2.9E-38 T 14-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 MB46_05705 32f3592b1b1d62176dea81dbb7098549 295 PRINTS PR00690 Adhesin family signature 23 41 2.9E-38 T 14-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 MB46_05705 32f3592b1b1d62176dea81dbb7098549 295 PRINTS PR00690 Adhesin family signature 256 275 2.9E-38 T 14-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 MB46_05705 32f3592b1b1d62176dea81dbb7098549 295 SUPERFAMILY SSF53807 21 290 2.6E-81 T 14-10-2018 MB46_05705 32f3592b1b1d62176dea81dbb7098549 295 Gene3D G3DSA:3.40.50.1980 179 295 8.8E-41 T 14-10-2018 MB46_05705 32f3592b1b1d62176dea81dbb7098549 295 Gene3D G3DSA:3.40.50.1980 23 178 2.5E-46 T 14-10-2018 MB46_05705 32f3592b1b1d62176dea81dbb7098549 295 PRINTS PR00691 Adhesin B signature 67 86 4.0E-32 T 14-10-2018 IPR006129 Adhesin B GO:0007155 MB46_05705 32f3592b1b1d62176dea81dbb7098549 295 PRINTS PR00691 Adhesin B signature 248 266 4.0E-32 T 14-10-2018 IPR006129 Adhesin B GO:0007155 MB46_05705 32f3592b1b1d62176dea81dbb7098549 295 PRINTS PR00691 Adhesin B signature 177 194 4.0E-32 T 14-10-2018 IPR006129 Adhesin B GO:0007155 MB46_05705 32f3592b1b1d62176dea81dbb7098549 295 PRINTS PR00691 Adhesin B signature 48 66 4.0E-32 T 14-10-2018 IPR006129 Adhesin B GO:0007155 MB46_05705 32f3592b1b1d62176dea81dbb7098549 295 PRINTS PR00691 Adhesin B signature 23 44 4.0E-32 T 14-10-2018 IPR006129 Adhesin B GO:0007155 MB46_05705 32f3592b1b1d62176dea81dbb7098549 295 PRINTS PR00691 Adhesin B signature 226 243 4.0E-32 T 14-10-2018 IPR006129 Adhesin B GO:0007155 MB46_05705 32f3592b1b1d62176dea81dbb7098549 295 PRINTS PR00691 Adhesin B signature 203 221 4.0E-32 T 14-10-2018 IPR006129 Adhesin B GO:0007155 MB46_05705 32f3592b1b1d62176dea81dbb7098549 295 Pfam PF01297 Zinc-uptake complex component A periplasmic 26 289 3.0E-69 T 14-10-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 MB46_00280 ad36b06e69a45c1f1391aa4dbe1c5f42 338 Pfam PF00294 pfkB family carbohydrate kinase 4 307 2.8E-46 T 14-10-2018 IPR011611 Carbohydrate kinase PfkB MB46_00280 ad36b06e69a45c1f1391aa4dbe1c5f42 338 Gene3D G3DSA:2.20.150.10 11 106 3.9E-93 T 14-10-2018 IPR023314 5-Dehydro-2-deoxygluconokinase-like superfamily KEGG: 00562+2.7.1.92 MB46_00280 ad36b06e69a45c1f1391aa4dbe1c5f42 338 PRINTS PR00990 Ribokinase signature 230 241 4.7E-5 T 14-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 MB46_00280 ad36b06e69a45c1f1391aa4dbe1c5f42 338 PRINTS PR00990 Ribokinase signature 30 49 4.7E-5 T 14-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 MB46_00280 ad36b06e69a45c1f1391aa4dbe1c5f42 338 PRINTS PR00990 Ribokinase signature 191 206 4.7E-5 T 14-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 MB46_00280 ad36b06e69a45c1f1391aa4dbe1c5f42 338 Gene3D G3DSA:3.40.1190.20 6 297 3.9E-93 T 14-10-2018 IPR029056 Ribokinase-like MB46_00280 ad36b06e69a45c1f1391aa4dbe1c5f42 338 TIGRFAM TIGR04382 myo_inos_iolC_N: 5-dehydro-2-deoxygluconokinase 4 314 2.7E-110 T 14-10-2018 IPR030830 5-Dehydro-2-deoxygluconokinase KEGG: 00562+2.7.1.92 MB46_00280 ad36b06e69a45c1f1391aa4dbe1c5f42 338 SUPERFAMILY SSF53613 4 315 3.27E-71 T 14-10-2018 IPR029056 Ribokinase-like MB46_02730 2b223fb44f0f7dba81d73b4bcc083780 403 SUPERFAMILY SSF69618 29 301 4.05E-48 T 14-10-2018 IPR036108 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase superfamily GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MB46_02730 2b223fb44f0f7dba81d73b4bcc083780 403 Gene3D G3DSA:1.10.10.10 301 398 1.1E-14 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_02730 2b223fb44f0f7dba81d73b4bcc083780 403 Pfam PF00486 Transcriptional regulatory protein, C terminal 328 395 2.0E-8 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MB46_02730 2b223fb44f0f7dba81d73b4bcc083780 403 Gene3D G3DSA:3.40.50.10090 60 191 2.7E-57 T 14-10-2018 MB46_02730 2b223fb44f0f7dba81d73b4bcc083780 403 Gene3D G3DSA:3.40.50.10090 34 292 2.7E-57 T 14-10-2018 MB46_02730 2b223fb44f0f7dba81d73b4bcc083780 403 SMART SM00862 326 395 2.9E-12 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MB46_02730 2b223fb44f0f7dba81d73b4bcc083780 403 SUPERFAMILY SSF46894 310 397 4.54E-11 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MB46_02730 2b223fb44f0f7dba81d73b4bcc083780 403 Pfam PF02602 Uroporphyrinogen-III synthase HemD 42 293 1.8E-38 T 14-10-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MB46_11180 1d04f839add88d13684b2f2fa48b225e 335 Gene3D G3DSA:3.40.50.720 3 308 1.3E-82 T 14-10-2018 MB46_11180 1d04f839add88d13684b2f2fa48b225e 335 Gene3D G3DSA:3.30.360.10 128 324 1.3E-82 T 14-10-2018 MB46_11180 1d04f839add88d13684b2f2fa48b225e 335 SUPERFAMILY SSF51735 2 152 1.72E-42 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_11180 1d04f839add88d13684b2f2fa48b225e 335 SUPERFAMILY SSF55347 128 291 1.8E-26 T 14-10-2018 MB46_11180 1d04f839add88d13684b2f2fa48b225e 335 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 3 118 1.2E-26 T 14-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 MB46_11180 1d04f839add88d13684b2f2fa48b225e 335 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 152 229 4.1E-9 T 14-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 MB46_10085 995a6f036061a35971314d14badebfe7 301 Gene3D G3DSA:1.10.600.10 8 285 1.8E-48 T 14-10-2018 IPR008949 Isoprenoid synthase domain superfamily MB46_10085 995a6f036061a35971314d14badebfe7 301 Pfam PF00494 Squalene/phytoene synthase 24 273 3.0E-34 T 14-10-2018 MB46_10085 995a6f036061a35971314d14badebfe7 301 SUPERFAMILY SSF48576 22 286 9.59E-53 T 14-10-2018 IPR008949 Isoprenoid synthase domain superfamily MB46_10085 995a6f036061a35971314d14badebfe7 301 ProSitePatterns PS01045 Squalene and phytoene synthases signature 2. 174 200 - T 14-10-2018 IPR019845 Squalene/phytoene synthase, conserved site GO:0016765 Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 MB46_04455 21d7a2c51c1f94e18667633ab48d98b9 395 Pfam PF01479 S4 domain 156 199 1.2E-10 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MB46_04455 21d7a2c51c1f94e18667633ab48d98b9 395 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 222 381 1.4E-44 T 14-10-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 MB46_04455 21d7a2c51c1f94e18667633ab48d98b9 395 SMART SM00363 156 214 4.5E-7 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MB46_04455 21d7a2c51c1f94e18667633ab48d98b9 395 SUPERFAMILY SSF55120 202 390 4.86E-42 T 14-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 MB46_04455 21d7a2c51c1f94e18667633ab48d98b9 395 Gene3D G3DSA:3.30.70.1560 281 371 1.0E-50 T 14-10-2018 MB46_04455 21d7a2c51c1f94e18667633ab48d98b9 395 SUPERFAMILY SSF55174 152 221 6.48E-12 T 14-10-2018 MB46_04455 21d7a2c51c1f94e18667633ab48d98b9 395 Gene3D G3DSA:3.10.290.10 151 213 9.7E-18 T 14-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 MB46_04455 21d7a2c51c1f94e18667633ab48d98b9 395 Pfam PF00849 RNA pseudouridylate synthase 218 351 5.5E-20 T 14-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 MB46_04455 21d7a2c51c1f94e18667633ab48d98b9 395 Gene3D G3DSA:3.30.70.580 220 379 1.0E-50 T 14-10-2018 MB46_04455 21d7a2c51c1f94e18667633ab48d98b9 395 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 257 271 - T 14-10-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 MB46_05790 c9b61d6a717f84270ef5beec9bb3aa2a 559 Gene3D G3DSA:1.10.3720.10 66 261 1.3E-23 T 14-10-2018 IPR035906 MetI-like superfamily MB46_05790 c9b61d6a717f84270ef5beec9bb3aa2a 559 Gene3D G3DSA:1.10.3720.10 359 558 4.1E-29 T 14-10-2018 IPR035906 MetI-like superfamily MB46_05790 c9b61d6a717f84270ef5beec9bb3aa2a 559 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 387 557 2.6E-15 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_05790 c9b61d6a717f84270ef5beec9bb3aa2a 559 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 90 250 1.1E-14 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_05790 c9b61d6a717f84270ef5beec9bb3aa2a 559 SUPERFAMILY SSF161098 66 252 7.85E-30 T 14-10-2018 IPR035906 MetI-like superfamily MB46_05790 c9b61d6a717f84270ef5beec9bb3aa2a 559 TIGRFAM TIGR01097 PhnE: phosphonate ABC transporter, permease protein PhnE 310 557 7.9E-67 T 14-10-2018 IPR005769 ABC transporter, permease PhnE/PtxC GO:0005887|GO:0015604|GO:0015716 MB46_05790 c9b61d6a717f84270ef5beec9bb3aa2a 559 SUPERFAMILY SSF161098 364 548 3.01E-30 T 14-10-2018 IPR035906 MetI-like superfamily MB46_05060 ced65cbf5207c26b5f29e544b77c13eb 335 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 326 4.2E-136 T 14-10-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MB46_05060 ced65cbf5207c26b5f29e544b77c13eb 335 Gene3D G3DSA:3.30.360.10 152 322 1.1E-152 T 14-10-2018 MB46_05060 ced65cbf5207c26b5f29e544b77c13eb 335 Gene3D G3DSA:3.40.50.720 4 327 1.1E-152 T 14-10-2018 MB46_05060 ced65cbf5207c26b5f29e544b77c13eb 335 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 151 158 - T 14-10-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MB46_05060 ced65cbf5207c26b5f29e544b77c13eb 335 SUPERFAMILY SSF55347 153 315 1.31E-70 T 14-10-2018 MB46_05060 ced65cbf5207c26b5f29e544b77c13eb 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 147 165 3.3E-38 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MB46_05060 ced65cbf5207c26b5f29e544b77c13eb 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 230 247 3.3E-38 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MB46_05060 ced65cbf5207c26b5f29e544b77c13eb 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 174 190 3.3E-38 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MB46_05060 ced65cbf5207c26b5f29e544b77c13eb 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 110 123 3.3E-38 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MB46_05060 ced65cbf5207c26b5f29e544b77c13eb 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 271 286 3.3E-38 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MB46_05060 ced65cbf5207c26b5f29e544b77c13eb 335 SUPERFAMILY SSF51735 2 180 4.81E-63 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_05060 ced65cbf5207c26b5f29e544b77c13eb 335 SMART SM00846 3 153 5.8E-95 T 14-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MB46_05060 ced65cbf5207c26b5f29e544b77c13eb 335 PIRSF PIRSF000149 1 335 6.8E-135 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MB46_05060 ced65cbf5207c26b5f29e544b77c13eb 335 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 4 103 1.0E-37 T 14-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MB46_05060 ced65cbf5207c26b5f29e544b77c13eb 335 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 158 314 3.6E-67 T 14-10-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MB46_11395 e717757ce24aaee49783b2218ce6dcc3 473 Gene3D G3DSA:3.40.50.720 193 457 1.1E-72 T 14-10-2018 MB46_11395 e717757ce24aaee49783b2218ce6dcc3 473 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 11 184 2.0E-94 T 14-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 MB46_11395 e717757ce24aaee49783b2218ce6dcc3 473 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 14 183 1.1E-40 T 14-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 MB46_11395 e717757ce24aaee49783b2218ce6dcc3 473 SUPERFAMILY SSF51182 8 187 1.53E-53 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily MB46_11395 e717757ce24aaee49783b2218ce6dcc3 473 Pfam PF04321 RmlD substrate binding domain 191 469 2.1E-66 T 14-10-2018 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581|Reactome: R-HSA-5689880 MB46_11395 e717757ce24aaee49783b2218ce6dcc3 473 Gene3D G3DSA:3.90.25.10 345 463 1.1E-72 T 14-10-2018 MB46_11395 e717757ce24aaee49783b2218ce6dcc3 473 Gene3D G3DSA:2.60.120.10 2 192 1.2E-54 T 14-10-2018 IPR014710 RmlC-like jelly roll fold MB46_11395 e717757ce24aaee49783b2218ce6dcc3 473 SUPERFAMILY SSF51735 191 469 7.41E-64 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_19370 b8b5eae0d1821ccd11eda04a687f0a07 318 SUPERFAMILY SSF52283 35 125 3.4E-6 T 14-10-2018 MB46_19370 b8b5eae0d1821ccd11eda04a687f0a07 318 SUPERFAMILY SSF51735 100 279 5.52E-40 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_19370 b8b5eae0d1821ccd11eda04a687f0a07 318 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 107 278 5.7E-42 T 14-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 MB46_19370 b8b5eae0d1821ccd11eda04a687f0a07 318 Gene3D G3DSA:3.40.50.720 96 277 4.8E-86 T 14-10-2018 MB46_19370 b8b5eae0d1821ccd11eda04a687f0a07 318 Gene3D G3DSA:3.40.50.720 2 300 4.8E-86 T 14-10-2018 MB46_19370 b8b5eae0d1821ccd11eda04a687f0a07 318 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 189 211 - T 14-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site MB46_04420 b8a12ffe4e5eda8bbca43079ec72140e 541 Pfam PF17203 Single cache domain 3 41 162 1.2E-27 T 14-10-2018 IPR033463 Single cache domain 3 MB46_04420 b8a12ffe4e5eda8bbca43079ec72140e 541 PRINTS PR00344 Bacterial sensor protein C-terminal signature 487 505 7.3E-6 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MB46_04420 b8a12ffe4e5eda8bbca43079ec72140e 541 PRINTS PR00344 Bacterial sensor protein C-terminal signature 454 468 7.3E-6 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MB46_04420 b8a12ffe4e5eda8bbca43079ec72140e 541 SUPERFAMILY SSF103190 38 163 2.43E-33 T 14-10-2018 IPR029151 Periplasmic sensor-like domain superfamily MB46_04420 b8a12ffe4e5eda8bbca43079ec72140e 541 SMART SM00387 414 525 1.6E-16 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MB46_04420 b8a12ffe4e5eda8bbca43079ec72140e 541 SUPERFAMILY SSF55874 387 534 1.7E-22 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MB46_04420 b8a12ffe4e5eda8bbca43079ec72140e 541 SUPERFAMILY SSF55785 205 309 7.44E-5 T 14-10-2018 IPR035965 PAS domain superfamily MB46_04420 b8a12ffe4e5eda8bbca43079ec72140e 541 Gene3D G3DSA:3.30.565.10 381 526 7.7E-19 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MB46_04420 b8a12ffe4e5eda8bbca43079ec72140e 541 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 415 523 9.3E-14 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MB46_04420 b8a12ffe4e5eda8bbca43079ec72140e 541 Gene3D G3DSA:3.30.450.20 33 169 1.4E-39 T 14-10-2018 MB46_04420 b8a12ffe4e5eda8bbca43079ec72140e 541 Gene3D G3DSA:3.30.450.20 199 311 5.7E-17 T 14-10-2018 MB46_04420 b8a12ffe4e5eda8bbca43079ec72140e 541 Pfam PF13188 PAS domain 212 275 3.4E-8 T 14-10-2018 IPR000014 PAS domain MB46_08475 a73757a582fa4506b3e645629a5292fe 1102 SMART SM01096 421 542 6.1E-55 T 14-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MB46_08475 a73757a582fa4506b3e645629a5292fe 1102 Pfam PF02142 MGS-like domain 971 1061 2.1E-20 T 14-10-2018 IPR011607 Methylglyoxal synthase-like domain MB46_08475 a73757a582fa4506b3e645629a5292fe 1102 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 334 2.0E-66 T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MB46_08475 a73757a582fa4506b3e645629a5292fe 1102 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 676 873 1.5E-33 T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MB46_08475 a73757a582fa4506b3e645629a5292fe 1102 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 164 178 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MB46_08475 a73757a582fa4506b3e645629a5292fe 1102 SMART SM00851 970 1061 1.3E-28 T 14-10-2018 IPR011607 Methylglyoxal synthase-like domain MB46_08475 a73757a582fa4506b3e645629a5292fe 1102 SUPERFAMILY SSF52335 957 1091 2.22E-31 T 14-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily MB46_08475 a73757a582fa4506b3e645629a5292fe 1102 SUPERFAMILY SSF48108 395 547 1.07E-44 T 14-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MB46_08475 a73757a582fa4506b3e645629a5292fe 1102 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 837 844 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MB46_08475 a73757a582fa4506b3e645629a5292fe 1102 SUPERFAMILY SSF52440 553 673 6.04E-44 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily MB46_08475 a73757a582fa4506b3e645629a5292fe 1102 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 425 542 2.1E-35 T 14-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MB46_08475 a73757a582fa4506b3e645629a5292fe 1102 Gene3D G3DSA:3.30.470.20 120 402 1.8E-120 T 14-10-2018 MB46_08475 a73757a582fa4506b3e645629a5292fe 1102 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 1073 0.0 T 14-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MB46_08475 a73757a582fa4506b3e645629a5292fe 1102 Gene3D G3DSA:3.40.50.20 549 661 7.5E-46 T 14-10-2018 MB46_08475 a73757a582fa4506b3e645629a5292fe 1102 SUPERFAMILY SSF56059 128 400 1.59E-103 T 14-10-2018 MB46_08475 a73757a582fa4506b3e645629a5292fe 1102 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 708 722 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MB46_08475 a73757a582fa4506b3e645629a5292fe 1102 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 2.1E-63 T 14-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MB46_08475 a73757a582fa4506b3e645629a5292fe 1102 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 2.1E-63 T 14-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MB46_08475 a73757a582fa4506b3e645629a5292fe 1102 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 2.1E-63 T 14-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MB46_08475 a73757a582fa4506b3e645629a5292fe 1102 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 297 326 2.1E-63 T 14-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MB46_08475 a73757a582fa4506b3e645629a5292fe 1102 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 379 397 2.1E-63 T 14-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MB46_08475 a73757a582fa4506b3e645629a5292fe 1102 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 2.1E-63 T 14-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MB46_08475 a73757a582fa4506b3e645629a5292fe 1102 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 2.1E-63 T 14-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MB46_08475 a73757a582fa4506b3e645629a5292fe 1102 Gene3D G3DSA:3.40.50.20 1 116 9.5E-48 T 14-10-2018 MB46_08475 a73757a582fa4506b3e645629a5292fe 1102 Gene3D G3DSA:1.10.1030.10 404 548 4.5E-38 T 14-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MB46_08475 a73757a582fa4506b3e645629a5292fe 1102 Gene3D G3DSA:3.40.50.1380 951 1093 1.5E-37 T 14-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily MB46_08475 a73757a582fa4506b3e645629a5292fe 1102 SUPERFAMILY SSF52440 1 127 9.78E-47 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily MB46_08475 a73757a582fa4506b3e645629a5292fe 1102 SUPERFAMILY SSF56059 673 947 2.47E-92 T 14-10-2018 MB46_08475 a73757a582fa4506b3e645629a5292fe 1102 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 297 304 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MB46_08475 a73757a582fa4506b3e645629a5292fe 1102 Gene3D G3DSA:3.30.470.20 664 950 7.0E-102 T 14-10-2018 MB46_08475 a73757a582fa4506b3e645629a5292fe 1102 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1082 12.763 T 14-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MB46_01360 e7af41be37d551cf3f73db1186e3797e 574 PIRSF PIRSF002741 15 563 1.2E-57 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 MB46_01360 e7af41be37d551cf3f73db1186e3797e 574 Gene3D G3DSA:3.10.105.10 319 544 1.5E-91 T 14-10-2018 MB46_01360 e7af41be37d551cf3f73db1186e3797e 574 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 109 484 2.3E-55 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain MB46_01360 e7af41be37d551cf3f73db1186e3797e 574 SUPERFAMILY SSF53850 59 573 2.9E-86 T 14-10-2018 MB46_01360 e7af41be37d551cf3f73db1186e3797e 574 Gene3D G3DSA:3.90.76.10 97 215 1.5E-91 T 14-10-2018 MB46_01360 e7af41be37d551cf3f73db1186e3797e 574 Gene3D G3DSA:3.40.190.10 67 555 1.5E-91 T 14-10-2018 MB46_14525 3ae2f50f02945cd0f4551722892530d5 557 Pfam PF01547 Bacterial extracellular solute-binding protein 137 419 1.4E-18 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein MB46_14525 3ae2f50f02945cd0f4551722892530d5 557 Gene3D G3DSA:3.40.190.10 107 490 1.4E-36 T 14-10-2018 MB46_14525 3ae2f50f02945cd0f4551722892530d5 557 SUPERFAMILY SSF53850 41 553 4.01E-58 T 14-10-2018 MB46_05525 c8105a2e2f65c6be72e8f744de46f2b8 264 SUPERFAMILY SSF53474 2 255 1.45E-44 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_05525 c8105a2e2f65c6be72e8f744de46f2b8 264 PRINTS PR00111 Alpha/beta hydrolase fold signature 87 100 1.3E-6 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MB46_05525 c8105a2e2f65c6be72e8f744de46f2b8 264 PRINTS PR00111 Alpha/beta hydrolase fold signature 42 57 1.3E-6 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MB46_05525 c8105a2e2f65c6be72e8f744de46f2b8 264 PRINTS PR00111 Alpha/beta hydrolase fold signature 101 114 1.3E-6 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MB46_05525 c8105a2e2f65c6be72e8f744de46f2b8 264 Gene3D G3DSA:3.40.50.1820 1 255 1.2E-45 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_05525 c8105a2e2f65c6be72e8f744de46f2b8 264 Pfam PF12146 Serine aminopeptidase, S33 18 114 8.9E-19 T 14-10-2018 IPR022742 Serine aminopeptidase, S33 MB46_08555 8da0d893d403397fd5a032c3e688cf1b 893 Pfam PF02272 DHHA1 domain 748 889 3.6E-19 T 14-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 MB46_08555 8da0d893d403397fd5a032c3e688cf1b 893 Pfam PF01411 tRNA synthetases class II (A) 6 569 2.8E-182 T 14-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 MB46_08555 8da0d893d403397fd5a032c3e688cf1b 893 Gene3D G3DSA:3.30.980.10 569 709 6.9E-38 T 14-10-2018 MB46_08555 8da0d893d403397fd5a032c3e688cf1b 893 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 666 710 5.0E-14 T 14-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 MB46_08555 8da0d893d403397fd5a032c3e688cf1b 893 Gene3D G3DSA:3.30.54.20 637 691 6.9E-38 T 14-10-2018 MB46_08555 8da0d893d403397fd5a032c3e688cf1b 893 PRINTS PR00980 Alanyl-tRNA synthetase signature 286 302 3.2E-29 T 14-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 MB46_08555 8da0d893d403397fd5a032c3e688cf1b 893 PRINTS PR00980 Alanyl-tRNA synthetase signature 310 323 3.2E-29 T 14-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 MB46_08555 8da0d893d403397fd5a032c3e688cf1b 893 PRINTS PR00980 Alanyl-tRNA synthetase signature 69 80 3.2E-29 T 14-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 MB46_08555 8da0d893d403397fd5a032c3e688cf1b 893 PRINTS PR00980 Alanyl-tRNA synthetase signature 229 242 3.2E-29 T 14-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 MB46_08555 8da0d893d403397fd5a032c3e688cf1b 893 PRINTS PR00980 Alanyl-tRNA synthetase signature 196 207 3.2E-29 T 14-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 MB46_08555 8da0d893d403397fd5a032c3e688cf1b 893 SUPERFAMILY SSF50447 466 565 6.71E-16 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily MB46_08555 8da0d893d403397fd5a032c3e688cf1b 893 SUPERFAMILY SSF101353 249 461 3.14E-53 T 14-10-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 MB46_08555 8da0d893d403397fd5a032c3e688cf1b 893 SUPERFAMILY SSF55186 565 724 4.06E-40 T 14-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 MB46_08555 8da0d893d403397fd5a032c3e688cf1b 893 Gene3D G3DSA:2.40.30.130 477 564 3.8E-10 T 14-10-2018 MB46_08555 8da0d893d403397fd5a032c3e688cf1b 893 Gene3D G3DSA:3.30.930.10 1 245 5.2E-91 T 14-10-2018 MB46_08555 8da0d893d403397fd5a032c3e688cf1b 893 SUPERFAMILY SSF55681 2 248 1.99E-85 T 14-10-2018 MB46_08555 8da0d893d403397fd5a032c3e688cf1b 893 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 6 872 2.8E-247 T 14-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 MB46_08555 8da0d893d403397fd5a032c3e688cf1b 893 SMART SM00863 666 710 9.8E-17 T 14-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 MB46_08555 8da0d893d403397fd5a032c3e688cf1b 893 Gene3D G3DSA:3.10.310.40 780 891 6.8E-19 T 14-10-2018 MB46_08555 8da0d893d403397fd5a032c3e688cf1b 893 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 893 161.691 T 14-10-2018 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 MB46_10870 7ec0de2153f3e1b5adfd221f649083bd 270 PRINTS PR00123 ATP synthase A subunit signature 102 118 2.7E-17 T 14-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MB46_10870 7ec0de2153f3e1b5adfd221f649083bd 270 PRINTS PR00123 ATP synthase A subunit signature 186 208 2.7E-17 T 14-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MB46_10870 7ec0de2153f3e1b5adfd221f649083bd 270 PRINTS PR00123 ATP synthase A subunit signature 248 263 2.7E-17 T 14-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MB46_10870 7ec0de2153f3e1b5adfd221f649083bd 270 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 43 263 1.1E-43 T 14-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MB46_10870 7ec0de2153f3e1b5adfd221f649083bd 270 SUPERFAMILY SSF81336 94 262 1.15E-33 T 14-10-2018 IPR035908 ATP synthase, F0 complex, subunit A superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MB46_10870 7ec0de2153f3e1b5adfd221f649083bd 270 Pfam PF00119 ATP synthase A chain 43 262 4.6E-46 T 14-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MB46_10870 7ec0de2153f3e1b5adfd221f649083bd 270 Gene3D G3DSA:1.20.120.220 94 268 4.0E-27 T 14-10-2018 IPR035908 ATP synthase, F0 complex, subunit A superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MB46_10870 7ec0de2153f3e1b5adfd221f649083bd 270 Hamap MF_01393 ATP synthase subunit a [atpB]. 21 268 13.184 T 14-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MB46_05815 cfd5be2a5df67f4a3bff5bfd978c89ec 470 Pfam PF00324 Amino acid permease 1 447 8.0E-137 T 14-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 MB46_05815 cfd5be2a5df67f4a3bff5bfd978c89ec 470 PIRSF PIRSF006060 1 459 3.0E-76 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 MB46_05815 cfd5be2a5df67f4a3bff5bfd978c89ec 470 Gene3D G3DSA:1.20.1740.10 1 452 2.6E-63 T 14-10-2018 MB46_05815 cfd5be2a5df67f4a3bff5bfd978c89ec 470 ProSitePatterns PS00218 Amino acid permeases signature. 23 54 - T 14-10-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 MB46_19690 6b15d6bb763b66d5d2fe37c5a14bb811 260 Gene3D G3DSA:3.40.50.150 9 234 2.2E-34 T 14-10-2018 MB46_19690 6b15d6bb763b66d5d2fe37c5a14bb811 260 SUPERFAMILY SSF53335 20 211 6.69E-32 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MB46_19690 6b15d6bb763b66d5d2fe37c5a14bb811 260 Pfam PF08241 Methyltransferase domain 46 142 2.1E-21 T 14-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 MB46_16810 de10a2a0bae00557c5057e0b9163552a 265 SUPERFAMILY SSF52096 9 264 9.65E-79 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MB46_16810 de10a2a0bae00557c5057e0b9163552a 265 Gene3D G3DSA:1.10.12.10 208 265 5.9E-19 T 14-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal MB46_16810 de10a2a0bae00557c5057e0b9163552a 265 Pfam PF00378 Enoyl-CoA hydratase/isomerase 22 264 4.3E-55 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 MB46_16810 de10a2a0bae00557c5057e0b9163552a 265 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 106 126 - T 14-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 MB46_16810 de10a2a0bae00557c5057e0b9163552a 265 Gene3D G3DSA:3.90.226.10 5 207 4.1E-70 T 14-10-2018 MB46_14875 d2152d46ba933b05ccdd0504cf8175af 83 Pfam PF02700 Phosphoribosylformylglycinamidine (FGAM) synthase 4 75 1.4E-24 T 14-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 MB46_14875 d2152d46ba933b05ccdd0504cf8175af 83 Hamap MF_01926 Phosphoribosylformylglycinamidine synthase subunit PurS [purS]. 2 79 18.802 T 14-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 MB46_14875 d2152d46ba933b05ccdd0504cf8175af 83 TIGRFAM TIGR00302 TIGR00302: phosphoribosylformylglycinamidine synthase, purS protein 6 74 1.6E-14 T 14-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 MB46_14875 d2152d46ba933b05ccdd0504cf8175af 83 ProDom PD010362 PHOSPHORIBOSYLFORMYLGLYCINAMIDINE PURS SYNTHETASE SYNTHASE COMPONENT SYNTHASE LIGASE FGAM UPF0062 I 11 70 9.0E-26 T 14-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 MB46_14875 d2152d46ba933b05ccdd0504cf8175af 83 Gene3D G3DSA:3.30.1280.10 3 83 4.7E-23 T 14-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MB46_14875 d2152d46ba933b05ccdd0504cf8175af 83 SUPERFAMILY SSF82697 4 74 1.4E-21 T 14-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MB46_16020 2051082ea7663b3770debbe725f9d571 502 Gene3D G3DSA:3.30.460.10 11 156 8.0E-35 T 14-10-2018 MB46_16020 2051082ea7663b3770debbe725f9d571 502 SUPERFAMILY SSF81891 155 473 1.15E-65 T 14-10-2018 MB46_16020 2051082ea7663b3770debbe725f9d571 502 Gene3D G3DSA:1.10.3090.10 157 456 1.5E-45 T 14-10-2018 MB46_16020 2051082ea7663b3770debbe725f9d571 502 Pfam PF01966 HD domain 259 364 8.7E-11 T 14-10-2018 IPR006674 HD domain MB46_16020 2051082ea7663b3770debbe725f9d571 502 Pfam PF01743 Poly A polymerase head domain 30 157 2.9E-31 T 14-10-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 MB46_16020 2051082ea7663b3770debbe725f9d571 502 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 184 244 3.9E-20 T 14-10-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 MB46_16020 2051082ea7663b3770debbe725f9d571 502 SMART SM00471 255 416 2.3E-6 T 14-10-2018 IPR003607 HD/PDEase domain MB46_16020 2051082ea7663b3770debbe725f9d571 502 TIGRFAM TIGR00277 HDIG: HDIG domain 256 333 1.3E-11 T 14-10-2018 IPR006675 HDIG domain MB46_16020 2051082ea7663b3770debbe725f9d571 502 TIGRFAM TIGR02692 tRNA_CCA_actino: CCA tRNA nucleotidyltransferase 8 471 4.8E-214 T 14-10-2018 IPR014065 tRNA adenylyltransferase MB46_16020 2051082ea7663b3770debbe725f9d571 502 SUPERFAMILY SSF81301 9 153 2.18E-34 T 14-10-2018 MB46_08190 6326e6da95e8aa1da79d0272cfd93f92 307 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 11 304 1.2E-82 T 14-10-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 MB46_08190 6326e6da95e8aa1da79d0272cfd93f92 307 Gene3D G3DSA:3.30.2350.10 80 306 5.8E-68 T 14-10-2018 MB46_08190 6326e6da95e8aa1da79d0272cfd93f92 307 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 134 148 - T 14-10-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 MB46_08190 6326e6da95e8aa1da79d0272cfd93f92 307 Pfam PF00849 RNA pseudouridylate synthase 88 242 3.2E-33 T 14-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 MB46_08190 6326e6da95e8aa1da79d0272cfd93f92 307 Gene3D G3DSA:3.10.290.10 1 68 2.6E-8 T 14-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 MB46_08190 6326e6da95e8aa1da79d0272cfd93f92 307 SUPERFAMILY SSF55120 76 304 4.32E-70 T 14-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 MB46_14550 db1332106446e6a5593e3212005212e7 727 SUPERFAMILY SSF51011 584 662 2.59E-21 T 14-10-2018 MB46_14550 db1332106446e6a5593e3212005212e7 727 Gene3D G3DSA:3.20.20.80 244 614 1.2E-146 T 14-10-2018 MB46_14550 db1332106446e6a5593e3212005212e7 727 Gene3D G3DSA:2.60.40.1180 615 662 2.7E-11 T 14-10-2018 IPR013780 Glycosyl hydrolase, all-beta MB46_14550 db1332106446e6a5593e3212005212e7 727 Gene3D G3DSA:2.60.40.1760 1 242 3.0E-72 T 14-10-2018 MB46_14550 db1332106446e6a5593e3212005212e7 727 SUPERFAMILY SSF117125 664 723 2.09E-9 T 14-10-2018 MB46_14550 db1332106446e6a5593e3212005212e7 727 SUPERFAMILY SSF74650 1 245 4.71E-60 T 14-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 MB46_14550 db1332106446e6a5593e3212005212e7 727 Pfam PF13802 Galactose mutarotase-like 158 216 3.8E-16 T 14-10-2018 IPR025887 Glycoside hydrolase family 31, N-terminal domain MB46_14550 db1332106446e6a5593e3212005212e7 727 Pfam PF01055 Glycosyl hydrolases family 31 238 667 3.1E-117 T 14-10-2018 IPR000322 Glycoside hydrolase family 31 GO:0004553|GO:0005975 MB46_14550 db1332106446e6a5593e3212005212e7 727 SUPERFAMILY SSF51445 260 600 2.3E-88 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily MB46_14550 db1332106446e6a5593e3212005212e7 727 Gene3D G3DSA:2.60.40.1180 663 727 1.6E-8 T 14-10-2018 IPR013780 Glycosyl hydrolase, all-beta MB46_04940 606564a59540842a16316cc0ca726d1f 875 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 1 159 2.4E-46 T 14-10-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 MB46_04940 606564a59540842a16316cc0ca726d1f 875 Gene3D G3DSA:1.20.1060.10 489 603 4.4E-30 T 14-10-2018 MB46_04940 606564a59540842a16316cc0ca726d1f 875 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 161 255 1.0E-25 T 14-10-2018 IPR020045 DNA polymerase I-like, H3TH domain GO:0003677|GO:0003824 MB46_04940 606564a59540842a16316cc0ca726d1f 875 Gene3D G3DSA:3.40.50.1010 1 267 7.4E-86 T 14-10-2018 MB46_04940 606564a59540842a16316cc0ca726d1f 875 SUPERFAMILY SSF56672 471 873 1.78E-133 T 14-10-2018 MB46_04940 606564a59540842a16316cc0ca726d1f 875 Gene3D G3DSA:1.10.150.20 655 798 5.2E-98 T 14-10-2018 MB46_04940 606564a59540842a16316cc0ca726d1f 875 TIGRFAM TIGR00593 pola: DNA polymerase I 1 873 2.0E-275 T 14-10-2018 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MB46_04940 606564a59540842a16316cc0ca726d1f 875 SMART SM00279 163 198 3.2E-10 T 14-10-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 MB46_04940 606564a59540842a16316cc0ca726d1f 875 Gene3D G3DSA:3.30.70.370 609 870 5.2E-98 T 14-10-2018 MB46_04940 606564a59540842a16316cc0ca726d1f 875 SUPERFAMILY SSF88723 2 159 8.18E-45 T 14-10-2018 IPR029060 PIN-like domain superfamily MB46_04940 606564a59540842a16316cc0ca726d1f 875 SMART SM00475 1 251 8.8E-104 T 14-10-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 MB46_04940 606564a59540842a16316cc0ca726d1f 875 Gene3D G3DSA:1.10.150.20 164 236 7.4E-86 T 14-10-2018 MB46_04940 606564a59540842a16316cc0ca726d1f 875 SUPERFAMILY SSF47807 161 274 6.73E-31 T 14-10-2018 IPR036279 5'-3' exonuclease, C-terminal domain superfamily MB46_04940 606564a59540842a16316cc0ca726d1f 875 SMART SM00474 295 464 2.8E-6 T 14-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 MB46_04940 606564a59540842a16316cc0ca726d1f 875 SUPERFAMILY SSF53098 299 465 4.93E-20 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily MB46_04940 606564a59540842a16316cc0ca726d1f 875 SMART SM00482 631 838 7.6E-102 T 14-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MB46_04940 606564a59540842a16316cc0ca726d1f 875 Pfam PF00476 DNA polymerase family A 496 871 8.4E-135 T 14-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MB46_04940 606564a59540842a16316cc0ca726d1f 875 Gene3D G3DSA:3.30.420.10 314 487 3.6E-24 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 MB46_04940 606564a59540842a16316cc0ca726d1f 875 PRINTS PR00868 DNA-polymerase family A (pol I) signature 700 725 4.6E-69 T 14-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MB46_04940 606564a59540842a16316cc0ca726d1f 875 PRINTS PR00868 DNA-polymerase family A (pol I) signature 791 807 4.6E-69 T 14-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MB46_04940 606564a59540842a16316cc0ca726d1f 875 PRINTS PR00868 DNA-polymerase family A (pol I) signature 759 770 4.6E-69 T 14-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MB46_04940 606564a59540842a16316cc0ca726d1f 875 PRINTS PR00868 DNA-polymerase family A (pol I) signature 600 622 4.6E-69 T 14-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MB46_04940 606564a59540842a16316cc0ca726d1f 875 PRINTS PR00868 DNA-polymerase family A (pol I) signature 676 689 4.6E-69 T 14-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MB46_04940 606564a59540842a16316cc0ca726d1f 875 PRINTS PR00868 DNA-polymerase family A (pol I) signature 623 638 4.6E-69 T 14-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MB46_04940 606564a59540842a16316cc0ca726d1f 875 PRINTS PR00868 DNA-polymerase family A (pol I) signature 737 748 4.6E-69 T 14-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MB46_04940 606564a59540842a16316cc0ca726d1f 875 PRINTS PR00868 DNA-polymerase family A (pol I) signature 646 669 4.6E-69 T 14-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MB46_04940 606564a59540842a16316cc0ca726d1f 875 PRINTS PR00868 DNA-polymerase family A (pol I) signature 821 834 4.6E-69 T 14-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MB46_03290 524a770d98f163bc655316e1bcbb71f2 393 Pfam PF01207 Dihydrouridine synthase (Dus) 30 337 3.1E-95 T 14-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 MB46_03290 524a770d98f163bc655316e1bcbb71f2 393 Gene3D G3DSA:3.20.20.70 23 269 2.1E-75 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MB46_03290 524a770d98f163bc655316e1bcbb71f2 393 TIGRFAM TIGR00737 nifR3_yhdG: putative TIM-barrel protein, nifR3 family 21 340 1.4E-108 T 14-10-2018 IPR004652 tRNA-dihydrouridine synthase, TIM-barrel, NifR3 GO:0008033|GO:0016491|GO:0050660|GO:0055114 MB46_03290 524a770d98f163bc655316e1bcbb71f2 393 PIRSF PIRSF006621 17 348 1.4E-98 T 14-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 MB46_03290 524a770d98f163bc655316e1bcbb71f2 393 SUPERFAMILY SSF51395 28 339 4.76E-80 T 14-10-2018 MB46_03290 524a770d98f163bc655316e1bcbb71f2 393 Gene3D G3DSA:1.10.1200.80 274 344 3.5E-9 T 14-10-2018 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 MB46_03290 524a770d98f163bc655316e1bcbb71f2 393 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 112 130 - T 14-10-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 MB46_15335 ff5d8d05e7d5f61d7f542ecccf6431fc 373 PIRSF PIRSF002756 6 371 3.1E-109 T 14-10-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 MB46_15335 ff5d8d05e7d5f61d7f542ecccf6431fc 373 TIGRFAM TIGR00975 3a0107s03: phosphate ABC transporter, phosphate-binding protein PstS 49 368 4.4E-68 T 14-10-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 MB46_15335 ff5d8d05e7d5f61d7f542ecccf6431fc 373 Pfam PF12849 PBP superfamily domain 39 338 8.9E-55 T 14-10-2018 IPR024370 PBP domain MB46_15335 ff5d8d05e7d5f61d7f542ecccf6431fc 373 Gene3D G3DSA:3.40.190.10 53 354 9.1E-95 T 14-10-2018 MB46_15335 ff5d8d05e7d5f61d7f542ecccf6431fc 373 Gene3D G3DSA:3.40.190.10 131 308 9.1E-95 T 14-10-2018 MB46_15335 ff5d8d05e7d5f61d7f542ecccf6431fc 373 SUPERFAMILY SSF53850 48 370 5.43E-82 T 14-10-2018 MB46_14455 4674b5eb2f5edd7326f0f52a4a3bf925 207 SUPERFAMILY SSF48498 99 205 2.15E-16 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily MB46_14455 4674b5eb2f5edd7326f0f52a4a3bf925 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 49 72 6.3E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MB46_14455 4674b5eb2f5edd7326f0f52a4a3bf925 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 28 41 6.3E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MB46_14455 4674b5eb2f5edd7326f0f52a4a3bf925 207 Gene3D G3DSA:1.10.357.10 78 207 8.1E-32 T 14-10-2018 MB46_14455 4674b5eb2f5edd7326f0f52a4a3bf925 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 29 72 6.5E-13 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MB46_14455 4674b5eb2f5edd7326f0f52a4a3bf925 207 Gene3D G3DSA:1.10.10.60 14 77 2.1E-17 T 14-10-2018 MB46_14455 4674b5eb2f5edd7326f0f52a4a3bf925 207 SUPERFAMILY SSF46689 18 85 8.72E-15 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MB46_02310 7110993b8d690ff61c4ff6e4c8cb2425 420 Gene3D G3DSA:2.40.440.10 264 408 1.4E-72 T 14-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like MB46_02310 7110993b8d690ff61c4ff6e4c8cb2425 420 SUPERFAMILY SSF141523 264 392 1.57E-17 T 14-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like MB46_02310 7110993b8d690ff61c4ff6e4c8cb2425 420 Gene3D G3DSA:2.60.40.3710 171 418 1.4E-72 T 14-10-2018 MB46_02310 7110993b8d690ff61c4ff6e4c8cb2425 420 Pfam PF03734 L,D-transpeptidase catalytic domain 274 391 7.2E-9 T 14-10-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 MB46_02310 7110993b8d690ff61c4ff6e4c8cb2425 420 Gene3D G3DSA:2.60.40.3780 65 162 5.2E-14 T 14-10-2018 MB46_16755 38858dcd03a50042f5e54eb6f6dbcb60 145 SUPERFAMILY SSF46785 7 144 2.7E-32 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_16755 38858dcd03a50042f5e54eb6f6dbcb60 145 SMART SM00347 27 133 7.4E-20 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MB46_16755 38858dcd03a50042f5e54eb6f6dbcb60 145 Gene3D G3DSA:1.10.10.10 3 145 9.9E-36 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_16755 38858dcd03a50042f5e54eb6f6dbcb60 145 Pfam PF12802 MarR family 34 97 7.5E-15 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MB46_16755 38858dcd03a50042f5e54eb6f6dbcb60 145 ProSitePatterns PS01117 MarR-type HTH domain signature. 72 106 - T 14-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site MB46_16755 38858dcd03a50042f5e54eb6f6dbcb60 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 93 109 6.1E-8 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MB46_16755 38858dcd03a50042f5e54eb6f6dbcb60 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 123 143 6.1E-8 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MB46_16755 38858dcd03a50042f5e54eb6f6dbcb60 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 74 89 6.1E-8 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MB46_18870 c2e6ff0569f4c63ae99d59a06968d700 513 SUPERFAMILY SSF52540 268 485 3.0E-44 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_18870 c2e6ff0569f4c63ae99d59a06968d700 513 Gene3D G3DSA:3.40.50.300 245 500 3.0E-42 T 14-10-2018 MB46_18870 c2e6ff0569f4c63ae99d59a06968d700 513 Pfam PF00005 ABC transporter 271 425 6.6E-20 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_18870 c2e6ff0569f4c63ae99d59a06968d700 513 SUPERFAMILY SSF52540 5 227 3.28E-53 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_18870 c2e6ff0569f4c63ae99d59a06968d700 513 Pfam PF00005 ABC transporter 21 171 4.6E-26 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_18870 c2e6ff0569f4c63ae99d59a06968d700 513 SMART SM00382 30 219 6.7E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_18870 c2e6ff0569f4c63ae99d59a06968d700 513 SMART SM00382 280 474 1.8E-5 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_18870 c2e6ff0569f4c63ae99d59a06968d700 513 ProSitePatterns PS00211 ABC transporters family signature. 398 412 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_18870 c2e6ff0569f4c63ae99d59a06968d700 513 Gene3D G3DSA:3.40.50.300 1 240 5.1E-51 T 14-10-2018 MB46_18255 45e9beac9ca1da06be62b9e188043d2e 247 Pfam PF06283 Trehalose utilisation 36 225 2.0E-31 T 14-10-2018 IPR029010 ThuA-like domain MB46_18255 45e9beac9ca1da06be62b9e188043d2e 247 PIRSF PIRSF030013 4 246 2.5E-102 T 14-10-2018 IPR009381 Trehalose catabolism protein, ThuA, prokaryote MB46_18255 45e9beac9ca1da06be62b9e188043d2e 247 Gene3D G3DSA:3.40.50.880 1 243 3.5E-98 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like MB46_18255 45e9beac9ca1da06be62b9e188043d2e 247 SUPERFAMILY SSF52317 4 229 8.01E-57 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like MB46_10195 0b149d1fb134a6a4340ba94de5fc709d 309 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 123 301 2.2E-20 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_10195 0b149d1fb134a6a4340ba94de5fc709d 309 SUPERFAMILY SSF161098 36 304 9.03E-67 T 14-10-2018 IPR035906 MetI-like superfamily MB46_10195 0b149d1fb134a6a4340ba94de5fc709d 309 Gene3D G3DSA:1.10.3720.10 31 299 5.3E-63 T 14-10-2018 IPR035906 MetI-like superfamily MB46_12890 87209379f88c33c30c9581b564500f51 346 Pfam PF00107 Zinc-binding dehydrogenase 185 307 6.8E-20 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 MB46_12890 87209379f88c33c30c9581b564500f51 346 Gene3D G3DSA:3.40.50.720 159 313 3.3E-137 T 14-10-2018 MB46_12890 87209379f88c33c30c9581b564500f51 346 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 14-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 MB46_12890 87209379f88c33c30c9581b564500f51 346 SUPERFAMILY SSF51735 148 311 6.37E-42 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_12890 87209379f88c33c30c9581b564500f51 346 Gene3D G3DSA:3.90.180.10 14 341 3.3E-137 T 14-10-2018 MB46_12890 87209379f88c33c30c9581b564500f51 346 SMART SM00829 11 341 6.9E-7 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MB46_12890 87209379f88c33c30c9581b564500f51 346 SUPERFAMILY SSF50129 6 171 6.85E-54 T 14-10-2018 IPR011032 GroES-like superfamily MB46_12890 87209379f88c33c30c9581b564500f51 346 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 143 1.3E-28 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MB46_12965 7c4b5c99f4360a0cb08e3d62642906f6 529 SUPERFAMILY SSF54810 408 529 6.28E-47 T 14-10-2018 MB46_12965 7c4b5c99f4360a0cb08e3d62642906f6 529 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 210 529 1.1E-141 T 14-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 MB46_12965 7c4b5c99f4360a0cb08e3d62642906f6 529 Gene3D G3DSA:3.40.50.620 207 408 6.5E-70 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MB46_12965 7c4b5c99f4360a0cb08e3d62642906f6 529 SUPERFAMILY SSF52317 12 234 1.43E-51 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like MB46_12965 7c4b5c99f4360a0cb08e3d62642906f6 529 SUPERFAMILY SSF52402 190 449 1.81E-52 T 14-10-2018 MB46_12965 7c4b5c99f4360a0cb08e3d62642906f6 529 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 14 197 1.0E-71 T 14-10-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 MB46_12965 7c4b5c99f4360a0cb08e3d62642906f6 529 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 85 101 2.3E-5 T 14-10-2018 MB46_12965 7c4b5c99f4360a0cb08e3d62642906f6 529 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 55 69 2.3E-5 T 14-10-2018 MB46_12965 7c4b5c99f4360a0cb08e3d62642906f6 529 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 14 28 2.3E-5 T 14-10-2018 MB46_12965 7c4b5c99f4360a0cb08e3d62642906f6 529 Gene3D G3DSA:3.40.50.880 11 206 1.4E-52 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like MB46_12965 7c4b5c99f4360a0cb08e3d62642906f6 529 Gene3D G3DSA:3.30.300.10 409 529 4.5E-51 T 14-10-2018 MB46_12965 7c4b5c99f4360a0cb08e3d62642906f6 529 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 11 529 52.877 T 14-10-2018 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 MB46_12965 7c4b5c99f4360a0cb08e3d62642906f6 529 PRINTS PR00097 Anthranilate synthase component II signature 58 67 1.1E-5 T 14-10-2018 MB46_12965 7c4b5c99f4360a0cb08e3d62642906f6 529 PRINTS PR00097 Anthranilate synthase component II signature 174 187 1.1E-5 T 14-10-2018 MB46_12965 7c4b5c99f4360a0cb08e3d62642906f6 529 PRINTS PR00097 Anthranilate synthase component II signature 85 96 1.1E-5 T 14-10-2018 MB46_12965 7c4b5c99f4360a0cb08e3d62642906f6 529 Pfam PF02540 NAD synthase 220 251 7.4E-7 T 14-10-2018 IPR022310 NAD/GMP synthase MB46_12965 7c4b5c99f4360a0cb08e3d62642906f6 529 Pfam PF00958 GMP synthase C terminal domain 437 528 3.5E-39 T 14-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 MB46_12965 7c4b5c99f4360a0cb08e3d62642906f6 529 Pfam PF00117 Glutamine amidotransferase class-I 16 196 1.8E-40 T 14-10-2018 IPR017926 Glutamine amidotransferase MB46_12965 7c4b5c99f4360a0cb08e3d62642906f6 529 PRINTS PR00096 Glutamine amidotransferase superfamily signature 174 187 4.6E-7 T 14-10-2018 MB46_12965 7c4b5c99f4360a0cb08e3d62642906f6 529 PRINTS PR00096 Glutamine amidotransferase superfamily signature 58 67 4.6E-7 T 14-10-2018 MB46_12965 7c4b5c99f4360a0cb08e3d62642906f6 529 PRINTS PR00096 Glutamine amidotransferase superfamily signature 85 96 4.6E-7 T 14-10-2018 MB46_18265 e7fd83d641a77f87c44d30386e5ab055 364 SUPERFAMILY SSF50156 253 360 1.45E-18 T 14-10-2018 IPR036034 PDZ superfamily GO:0005515 MB46_18265 e7fd83d641a77f87c44d30386e5ab055 364 SUPERFAMILY SSF50494 39 279 8.97E-55 T 14-10-2018 IPR009003 Peptidase S1, PA clan MB46_18265 e7fd83d641a77f87c44d30386e5ab055 364 Gene3D G3DSA:2.40.10.10 52 144 5.3E-27 T 14-10-2018 MB46_18265 e7fd83d641a77f87c44d30386e5ab055 364 SMART SM00228 271 351 1.3E-6 T 14-10-2018 IPR001478 PDZ domain GO:0005515 MB46_18265 e7fd83d641a77f87c44d30386e5ab055 364 Gene3D G3DSA:2.40.10.10 146 267 5.4E-40 T 14-10-2018 MB46_18265 e7fd83d641a77f87c44d30386e5ab055 364 Pfam PF13180 PDZ domain 273 360 1.2E-14 T 14-10-2018 IPR001478 PDZ domain GO:0005515 MB46_18265 e7fd83d641a77f87c44d30386e5ab055 364 Gene3D G3DSA:2.30.42.10 268 364 8.1E-22 T 14-10-2018 MB46_18265 e7fd83d641a77f87c44d30386e5ab055 364 Pfam PF13365 Trypsin-like peptidase domain 82 226 5.1E-33 T 14-10-2018 MB46_18265 e7fd83d641a77f87c44d30386e5ab055 364 PRINTS PR00834 HtrA/DegQ protease family signature 156 180 4.6E-44 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MB46_18265 e7fd83d641a77f87c44d30386e5ab055 364 PRINTS PR00834 HtrA/DegQ protease family signature 219 236 4.6E-44 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MB46_18265 e7fd83d641a77f87c44d30386e5ab055 364 PRINTS PR00834 HtrA/DegQ protease family signature 309 321 4.6E-44 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MB46_18265 e7fd83d641a77f87c44d30386e5ab055 364 PRINTS PR00834 HtrA/DegQ protease family signature 197 214 4.6E-44 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MB46_18265 e7fd83d641a77f87c44d30386e5ab055 364 PRINTS PR00834 HtrA/DegQ protease family signature 91 103 4.6E-44 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MB46_18265 e7fd83d641a77f87c44d30386e5ab055 364 PRINTS PR00834 HtrA/DegQ protease family signature 115 135 4.6E-44 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MB46_18210 d4eae2705a4b86cdc584ff4c7afb5d66 402 SUPERFAMILY SSF51735 9 172 7.45E-44 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_18210 d4eae2705a4b86cdc584ff4c7afb5d66 402 Gene3D G3DSA:3.30.360.10 145 381 3.6E-74 T 14-10-2018 MB46_18210 d4eae2705a4b86cdc584ff4c7afb5d66 402 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 13 131 6.6E-21 T 14-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 MB46_18210 d4eae2705a4b86cdc584ff4c7afb5d66 402 Gene3D G3DSA:3.40.50.720 8 144 2.1E-34 T 14-10-2018 MB46_18210 d4eae2705a4b86cdc584ff4c7afb5d66 402 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 152 273 2.7E-13 T 14-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 MB46_18210 d4eae2705a4b86cdc584ff4c7afb5d66 402 SUPERFAMILY SSF55347 146 307 4.32E-38 T 14-10-2018 MB46_08535 5276f42b6016947b2109420c0610b357 399 ProSitePatterns PS00788 Chorismate synthase signature 2. 134 150 - T 14-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 MB46_08535 5276f42b6016947b2109420c0610b357 399 PIRSF PIRSF001456 1 385 2.4E-124 T 14-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 MB46_08535 5276f42b6016947b2109420c0610b357 399 TIGRFAM TIGR00033 aroC: chorismate synthase 2 373 3.6E-128 T 14-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 MB46_08535 5276f42b6016947b2109420c0610b357 399 Hamap MF_00300 Chorismate synthase [aroC]. 2 375 33.711 T 14-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 MB46_08535 5276f42b6016947b2109420c0610b357 399 ProSitePatterns PS00787 Chorismate synthase signature 1. 8 23 - T 14-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 MB46_08535 5276f42b6016947b2109420c0610b357 399 SUPERFAMILY SSF103263 2 389 6.67E-138 T 14-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 MB46_08535 5276f42b6016947b2109420c0610b357 399 ProSitePatterns PS00789 Chorismate synthase signature 3. 342 358 - T 14-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 MB46_08535 5276f42b6016947b2109420c0610b357 399 Gene3D G3DSA:3.60.150.10 1 397 2.0E-156 T 14-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 MB46_08535 5276f42b6016947b2109420c0610b357 399 Pfam PF01264 Chorismate synthase 2 367 7.9E-117 T 14-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 MB46_09950 bd1135bead08bdbed47d2785ee0ecce2 176 Pfam PF08002 Protein of unknown function (DUF1697) 1 115 5.5E-32 T 14-10-2018 IPR012545 Protein of unknown function DUF1697 MB46_09950 bd1135bead08bdbed47d2785ee0ecce2 176 Gene3D G3DSA:3.30.70.1280 1 87 5.4E-19 T 14-10-2018 MB46_09950 bd1135bead08bdbed47d2785ee0ecce2 176 SUPERFAMILY SSF160379 1 173 2.09E-42 T 14-10-2018 MB46_09950 bd1135bead08bdbed47d2785ee0ecce2 176 PIRSF PIRSF008502 1 176 1.1E-38 T 14-10-2018 IPR012545 Protein of unknown function DUF1697 MB46_06840 8b92c2a0e098514dc11b1808b31fcf71 203 Pfam PF04229 GrpB protein 33 193 5.5E-46 T 14-10-2018 IPR007344 GrpB/Dephospho-CoA kinase MB46_06840 8b92c2a0e098514dc11b1808b31fcf71 203 SUPERFAMILY SSF81301 34 196 2.42E-41 T 14-10-2018 MB46_06840 8b92c2a0e098514dc11b1808b31fcf71 203 Gene3D G3DSA:3.30.460.10 29 198 1.4E-43 T 14-10-2018 MB46_09690 8182005210af7b3ea6d1a66c548b80b0 483 SUPERFAMILY SSF51679 15 456 1.43E-98 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 MB46_09690 8182005210af7b3ea6d1a66c548b80b0 483 PIRSF PIRSF000337 15 464 3.6E-116 T 14-10-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 MB46_09690 8182005210af7b3ea6d1a66c548b80b0 483 Pfam PF00296 Luciferase-like monooxygenase 18 406 2.9E-47 T 14-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MB46_09690 8182005210af7b3ea6d1a66c548b80b0 483 Gene3D G3DSA:3.20.20.30 11 467 5.5E-114 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 MB46_09690 8182005210af7b3ea6d1a66c548b80b0 483 TIGRFAM TIGR03860 FMN_nitrolo: FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family 28 450 2.2E-111 T 14-10-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 MB46_04645 77aa67f3963f24d27420a8987bfc356d 321 Hamap MF_00367 GTPase Era [era]. 18 321 33.566 T 14-10-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_04645 77aa67f3963f24d27420a8987bfc356d 321 SUPERFAMILY SSF52540 24 232 7.76E-38 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_04645 77aa67f3963f24d27420a8987bfc356d 321 Gene3D G3DSA:3.30.300.20 205 321 2.4E-38 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta MB46_04645 77aa67f3963f24d27420a8987bfc356d 321 SUPERFAMILY SSF54814 202 321 2.42E-33 T 14-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 MB46_04645 77aa67f3963f24d27420a8987bfc356d 321 Gene3D G3DSA:3.40.50.300 18 203 1.2E-39 T 14-10-2018 MB46_04645 77aa67f3963f24d27420a8987bfc356d 321 Pfam PF01926 50S ribosome-binding GTPase 24 138 6.7E-21 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 MB46_04645 77aa67f3963f24d27420a8987bfc356d 321 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 24 177 1.3E-19 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MB46_04645 77aa67f3963f24d27420a8987bfc356d 321 Pfam PF07650 KH domain 228 310 4.1E-15 T 14-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MB46_04645 77aa67f3963f24d27420a8987bfc356d 321 TIGRFAM TIGR00436 era: GTP-binding protein Era 22 304 1.8E-63 T 14-10-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_17620 5d4f6ec0e2c7e8514b99d745b4d5ee0e 344 SMART SM00354 9 79 8.2E-25 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MB46_17620 5d4f6ec0e2c7e8514b99d745b4d5ee0e 344 ProSitePatterns PS00356 LacI-type HTH domain signature. 12 30 - T 14-10-2018 MB46_17620 5d4f6ec0e2c7e8514b99d745b4d5ee0e 344 SUPERFAMILY SSF53822 68 335 2.94E-60 T 14-10-2018 IPR028082 Periplasmic binding protein-like I MB46_17620 5d4f6ec0e2c7e8514b99d745b4d5ee0e 344 Gene3D G3DSA:1.10.260.40 9 67 1.2E-20 T 14-10-2018 MB46_17620 5d4f6ec0e2c7e8514b99d745b4d5ee0e 344 Pfam PF00356 Bacterial regulatory proteins, lacI family 12 56 1.5E-15 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MB46_17620 5d4f6ec0e2c7e8514b99d745b4d5ee0e 344 Pfam PF13377 Periplasmic binding protein-like domain 176 332 2.4E-33 T 14-10-2018 MB46_17620 5d4f6ec0e2c7e8514b99d745b4d5ee0e 344 SUPERFAMILY SSF47413 9 67 4.74E-16 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MB46_17620 5d4f6ec0e2c7e8514b99d745b4d5ee0e 344 Gene3D G3DSA:3.40.50.2300 167 292 1.9E-65 T 14-10-2018 MB46_17620 5d4f6ec0e2c7e8514b99d745b4d5ee0e 344 Gene3D G3DSA:3.40.50.2300 68 304 1.9E-65 T 14-10-2018 MB46_08825 f19b0d296aff8961328d48432655dd27 196 SUPERFAMILY SSF46689 16 96 2.05E-17 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MB46_08825 f19b0d296aff8961328d48432655dd27 196 Gene3D G3DSA:1.10.357.10 17 196 1.8E-54 T 14-10-2018 MB46_08825 f19b0d296aff8961328d48432655dd27 196 SUPERFAMILY SSF48498 114 194 1.56E-6 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily MB46_08825 f19b0d296aff8961328d48432655dd27 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 29 74 9.6E-11 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MB46_08825 f19b0d296aff8961328d48432655dd27 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 50 73 4.5E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MB46_08825 f19b0d296aff8961328d48432655dd27 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 42 4.5E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MB46_12785 b381427f60bd4c50abc7b0afd81d364d 162 Gene3D G3DSA:1.10.10.10 2 145 2.2E-26 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_12785 b381427f60bd4c50abc7b0afd81d364d 162 SMART SM00347 27 131 1.3E-17 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MB46_12785 b381427f60bd4c50abc7b0afd81d364d 162 Pfam PF01047 MarR family 54 96 9.5E-10 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MB46_12785 b381427f60bd4c50abc7b0afd81d364d 162 PRINTS PR00598 Bacterial regulatory protein MarR family signature 91 107 1.6E-5 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MB46_12785 b381427f60bd4c50abc7b0afd81d364d 162 PRINTS PR00598 Bacterial regulatory protein MarR family signature 72 87 1.6E-5 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MB46_12785 b381427f60bd4c50abc7b0afd81d364d 162 PRINTS PR00598 Bacterial regulatory protein MarR family signature 55 71 1.6E-5 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MB46_12785 b381427f60bd4c50abc7b0afd81d364d 162 SUPERFAMILY SSF46785 7 142 3.0E-23 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_03630 e5290b6856f9e62d596d57a727c0a5ff 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 68 84 6.4E-5 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MB46_03630 e5290b6856f9e62d596d57a727c0a5ff 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 85 100 6.4E-5 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MB46_03630 e5290b6856f9e62d596d57a727c0a5ff 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 104 120 6.4E-5 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MB46_03630 e5290b6856f9e62d596d57a727c0a5ff 165 Pfam PF12802 MarR family 47 108 2.7E-12 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MB46_03630 e5290b6856f9e62d596d57a727c0a5ff 165 SUPERFAMILY SSF46785 12 160 1.21E-25 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_03630 e5290b6856f9e62d596d57a727c0a5ff 165 Gene3D G3DSA:1.10.10.10 16 162 5.2E-34 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_03630 e5290b6856f9e62d596d57a727c0a5ff 165 SMART SM00347 42 145 1.6E-6 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MB46_08950 2e33283c1a62aab436a9b4869e862cf9 388 ProSitePatterns PS00902 Glutamate 5-kinase signature. 228 245 - T 14-10-2018 IPR019797 Glutamate 5-kinase, conserved site GO:0004349|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 MB46_08950 2e33283c1a62aab436a9b4869e862cf9 388 Gene3D G3DSA:2.30.130.10 284 386 5.3E-28 T 14-10-2018 IPR036974 PUA domain superfamily GO:0003723 MB46_08950 2e33283c1a62aab436a9b4869e862cf9 388 Pfam PF01472 PUA domain 295 363 1.4E-16 T 14-10-2018 IPR002478 PUA domain GO:0003723 MB46_08950 2e33283c1a62aab436a9b4869e862cf9 388 PRINTS PR00474 Glutamate 5-kinase family signature 170 197 7.3E-54 T 14-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 MB46_08950 2e33283c1a62aab436a9b4869e862cf9 388 PRINTS PR00474 Glutamate 5-kinase family signature 230 250 7.3E-54 T 14-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 MB46_08950 2e33283c1a62aab436a9b4869e862cf9 388 PRINTS PR00474 Glutamate 5-kinase family signature 98 126 7.3E-54 T 14-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 MB46_08950 2e33283c1a62aab436a9b4869e862cf9 388 PRINTS PR00474 Glutamate 5-kinase family signature 64 78 7.3E-54 T 14-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 MB46_08950 2e33283c1a62aab436a9b4869e862cf9 388 PRINTS PR00474 Glutamate 5-kinase family signature 138 159 7.3E-54 T 14-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 MB46_08950 2e33283c1a62aab436a9b4869e862cf9 388 Hamap MF_00456 Glutamate 5-kinase [proB]. 27 283 34.1 T 14-10-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 MB46_08950 2e33283c1a62aab436a9b4869e862cf9 388 SMART SM00359 295 374 5.5E-14 T 14-10-2018 IPR002478 PUA domain GO:0003723 MB46_08950 2e33283c1a62aab436a9b4869e862cf9 388 SUPERFAMILY SSF88697 294 385 3.65E-20 T 14-10-2018 IPR015947 PUA-like superfamily MB46_08950 2e33283c1a62aab436a9b4869e862cf9 388 Gene3D G3DSA:3.40.1160.10 16 278 5.0E-80 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily MB46_08950 2e33283c1a62aab436a9b4869e862cf9 388 PIRSF PIRSF000729 23 387 4.9E-119 T 14-10-2018 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 MB46_08950 2e33283c1a62aab436a9b4869e862cf9 388 TIGRFAM TIGR01027 proB: glutamate 5-kinase 28 384 1.0E-121 T 14-10-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 MB46_08950 2e33283c1a62aab436a9b4869e862cf9 388 Pfam PF00696 Amino acid kinase family 28 256 2.0E-43 T 14-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 MB46_08950 2e33283c1a62aab436a9b4869e862cf9 388 SUPERFAMILY SSF53633 28 273 3.01E-62 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily MB46_16335 06861d07c4b7e2127bc1e567bbb092bb 457 Pfam PF01554 MatE 259 404 6.4E-16 T 14-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 MB46_16335 06861d07c4b7e2127bc1e567bbb092bb 457 Pfam PF01554 MatE 28 188 3.4E-28 T 14-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 MB46_16335 06861d07c4b7e2127bc1e567bbb092bb 457 PIRSF PIRSF006603 11 456 1.2E-57 T 14-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 MB46_16335 06861d07c4b7e2127bc1e567bbb092bb 457 TIGRFAM TIGR00797 matE: MATE efflux family protein 28 408 1.1E-87 T 14-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 MB46_14495 54bd0aaa52076030a413510b68ae80de 284 Pfam PF01163 RIO1 family 105 269 6.6E-30 T 14-10-2018 MB46_14495 54bd0aaa52076030a413510b68ae80de 284 Gene3D G3DSA:3.30.200.20 60 174 2.5E-7 T 14-10-2018 MB46_14495 54bd0aaa52076030a413510b68ae80de 284 SMART SM00090 38 282 7.6E-9 T 14-10-2018 IPR000687 RIO kinase GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 MB46_14495 54bd0aaa52076030a413510b68ae80de 284 Gene3D G3DSA:1.10.510.10 182 281 4.2E-17 T 14-10-2018 MB46_14495 54bd0aaa52076030a413510b68ae80de 284 SUPERFAMILY SSF56112 64 244 1.78E-17 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily MB46_07850 3c872ba3f840e73ce0b53f1704bf9e27 714 Pfam PF00378 Enoyl-CoA hydratase/isomerase 55 245 4.9E-16 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 MB46_07850 3c872ba3f840e73ce0b53f1704bf9e27 714 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 351 530 2.1E-56 T 14-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 MB46_07850 3c872ba3f840e73ce0b53f1704bf9e27 714 SUPERFAMILY SSF48179 533 626 6.29E-16 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MB46_07850 3c872ba3f840e73ce0b53f1704bf9e27 714 SUPERFAMILY SSF52096 53 335 1.49E-32 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MB46_07850 3c872ba3f840e73ce0b53f1704bf9e27 714 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 534 616 2.8E-13 T 14-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 MB46_07850 3c872ba3f840e73ce0b53f1704bf9e27 714 Gene3D G3DSA:3.90.226.10 38 340 8.7E-49 T 14-10-2018 MB46_07850 3c872ba3f840e73ce0b53f1704bf9e27 714 Gene3D G3DSA:1.10.1040.50 536 713 1.0E-30 T 14-10-2018 MB46_07850 3c872ba3f840e73ce0b53f1704bf9e27 714 Gene3D G3DSA:3.40.50.720 348 535 2.8E-59 T 14-10-2018 MB46_07850 3c872ba3f840e73ce0b53f1704bf9e27 714 SUPERFAMILY SSF48179 651 705 2.38E-11 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MB46_07850 3c872ba3f840e73ce0b53f1704bf9e27 714 SUPERFAMILY SSF51735 349 530 2.15E-50 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_16975 c17e4d72b8f82b9e786f5c0a9b0771ec 513 Gene3D G3DSA:3.40.50.300 8 263 2.7E-59 T 14-10-2018 MB46_16975 c17e4d72b8f82b9e786f5c0a9b0771ec 513 SMART SM00382 312 500 1.2E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_16975 c17e4d72b8f82b9e786f5c0a9b0771ec 513 SMART SM00382 38 265 2.7E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_16975 c17e4d72b8f82b9e786f5c0a9b0771ec 513 SUPERFAMILY SSF52540 307 496 1.31E-38 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_16975 c17e4d72b8f82b9e786f5c0a9b0771ec 513 ProSitePatterns PS00211 ABC transporters family signature. 424 438 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_16975 c17e4d72b8f82b9e786f5c0a9b0771ec 513 Pfam PF00005 ABC transporter 30 175 4.2E-24 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_16975 c17e4d72b8f82b9e786f5c0a9b0771ec 513 SUPERFAMILY SSF52540 18 246 4.41E-49 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_16975 c17e4d72b8f82b9e786f5c0a9b0771ec 513 Pfam PF00005 ABC transporter 307 451 1.3E-23 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_16975 c17e4d72b8f82b9e786f5c0a9b0771ec 513 Gene3D G3DSA:3.40.50.300 282 506 1.5E-42 T 14-10-2018 MB46_16975 c17e4d72b8f82b9e786f5c0a9b0771ec 513 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_06755 dfc7dec852c6937b7aae921e7518900a 89 SUPERFAMILY SSF81665 5 74 4.32E-10 T 14-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 MB46_06755 dfc7dec852c6937b7aae921e7518900a 89 Gene3D G3DSA:2.70.150.10 4 83 2.9E-7 T 14-10-2018 MB46_06755 dfc7dec852c6937b7aae921e7518900a 89 Gene3D G3DSA:1.20.1110.10 14 69 2.9E-7 T 14-10-2018 MB46_11870 98b6fb436e76c59842ac140140a4e5f0 314 Gene3D G3DSA:3.40.50.720 10 177 4.0E-50 T 14-10-2018 MB46_11870 98b6fb436e76c59842ac140140a4e5f0 314 TIGRFAM TIGR01692 HIBADH: 3-hydroxyisobutyrate dehydrogenase 17 307 1.5E-111 T 14-10-2018 IPR011548 3-hydroxyisobutyrate dehydrogenase GO:0008442|GO:0051287|GO:0055114 KEGG: 00280+1.1.1.31|Reactome: R-HSA-70895 MB46_11870 98b6fb436e76c59842ac140140a4e5f0 314 Gene3D G3DSA:1.10.1040.10 179 309 1.9E-40 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MB46_11870 98b6fb436e76c59842ac140140a4e5f0 314 SUPERFAMILY SSF48179 177 307 8.05E-37 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MB46_11870 98b6fb436e76c59842ac140140a4e5f0 314 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 17 30 - T 14-10-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 MB46_11870 98b6fb436e76c59842ac140140a4e5f0 314 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 179 305 1.5E-36 T 14-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 MB46_11870 98b6fb436e76c59842ac140140a4e5f0 314 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 14 176 8.2E-45 T 14-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 MB46_11870 98b6fb436e76c59842ac140140a4e5f0 314 SUPERFAMILY SSF51735 14 176 3.35E-40 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_11870 98b6fb436e76c59842ac140140a4e5f0 314 PIRSF PIRSF000103 11 314 4.7E-74 T 14-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 MB46_09745 144799daee96cef413d8334ab48ae56e 337 SUPERFAMILY SSF51735 7 333 3.66E-59 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_09745 144799daee96cef413d8334ab48ae56e 337 Pfam PF01370 NAD dependent epimerase/dehydratase family 9 224 2.1E-29 T 14-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 MB46_09745 144799daee96cef413d8334ab48ae56e 337 Gene3D G3DSA:3.40.50.720 2 334 3.1E-64 T 14-10-2018 MB46_11130 041dcb5128a68057102d82f210b1a0df 473 TIGRFAM TIGR00792 gph: sugar (Glycoside-Pentoside-Hexuronide) transporter 24 455 2.7E-124 T 14-10-2018 IPR001927 Sodium:galactoside symporter GO:0005215|GO:0006814|GO:0016020 MB46_11130 041dcb5128a68057102d82f210b1a0df 473 Gene3D G3DSA:1.20.1250.20 20 219 3.1E-13 T 14-10-2018 MB46_11130 041dcb5128a68057102d82f210b1a0df 473 SUPERFAMILY SSF103473 23 440 1.48E-32 T 14-10-2018 IPR036259 MFS transporter superfamily MB46_11130 041dcb5128a68057102d82f210b1a0df 473 Pfam PF13347 MFS/sugar transport protein 25 442 1.1E-94 T 14-10-2018 MB46_11130 041dcb5128a68057102d82f210b1a0df 473 Gene3D G3DSA:1.20.1250.20 229 447 1.2E-9 T 14-10-2018 MB46_16440 11810039afc95f80e5b6b7fe6f51c87e 331 SUPERFAMILY SSF51735 142 298 1.01E-29 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_16440 11810039afc95f80e5b6b7fe6f51c87e 331 Gene3D G3DSA:3.90.180.10 9 316 3.5E-97 T 14-10-2018 MB46_16440 11810039afc95f80e5b6b7fe6f51c87e 331 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 61 75 - T 14-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 MB46_16440 11810039afc95f80e5b6b7fe6f51c87e 331 Pfam PF00107 Zinc-binding dehydrogenase 175 293 4.2E-15 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 MB46_16440 11810039afc95f80e5b6b7fe6f51c87e 331 Gene3D G3DSA:3.40.50.720 152 279 3.5E-97 T 14-10-2018 MB46_16440 11810039afc95f80e5b6b7fe6f51c87e 331 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 24 135 2.7E-23 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MB46_16440 11810039afc95f80e5b6b7fe6f51c87e 331 SUPERFAMILY SSF50129 4 173 2.43E-49 T 14-10-2018 IPR011032 GroES-like superfamily MB46_00360 4f3be3dc164617e4113d23eec47b5126 335 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 47 1.1E-15 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MB46_00360 4f3be3dc164617e4113d23eec47b5126 335 SMART SM00354 1 71 1.2E-25 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MB46_00360 4f3be3dc164617e4113d23eec47b5126 335 SUPERFAMILY SSF53822 58 302 1.16E-61 T 14-10-2018 IPR028082 Periplasmic binding protein-like I MB46_00360 4f3be3dc164617e4113d23eec47b5126 335 Gene3D G3DSA:1.10.260.40 3 55 4.5E-19 T 14-10-2018 MB46_00360 4f3be3dc164617e4113d23eec47b5126 335 SUPERFAMILY SSF47413 2 59 2.31E-14 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MB46_00360 4f3be3dc164617e4113d23eec47b5126 335 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 2.9E-6 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MB46_00360 4f3be3dc164617e4113d23eec47b5126 335 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 2.9E-6 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MB46_00360 4f3be3dc164617e4113d23eec47b5126 335 Gene3D G3DSA:3.40.50.2300 56 301 2.5E-68 T 14-10-2018 MB46_00360 4f3be3dc164617e4113d23eec47b5126 335 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 14-10-2018 MB46_00360 4f3be3dc164617e4113d23eec47b5126 335 Pfam PF13377 Periplasmic binding protein-like domain 166 320 5.7E-32 T 14-10-2018 MB46_00360 4f3be3dc164617e4113d23eec47b5126 335 Gene3D G3DSA:3.40.50.2300 158 285 2.5E-68 T 14-10-2018 MB46_06045 0147d6ba2fe56936d110d6b0d4ce1128 161 Pfam PF01047 MarR family 36 95 5.7E-13 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MB46_06045 0147d6ba2fe56936d110d6b0d4ce1128 161 Gene3D G3DSA:1.10.10.10 2 146 6.1E-29 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_06045 0147d6ba2fe56936d110d6b0d4ce1128 161 SMART SM00347 29 128 1.0E-16 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MB46_06045 0147d6ba2fe56936d110d6b0d4ce1128 161 SUPERFAMILY SSF46785 5 146 2.83E-28 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_04550 d98378da29b1de1c40e0193ff29443ab 504 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 3 498 9.2E-227 T 14-10-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 MB46_04550 d98378da29b1de1c40e0193ff29443ab 504 Hamap MF_00186 Glycerol kinase [glpK]. 2 499 56.037 T 14-10-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 MB46_04550 d98378da29b1de1c40e0193ff29443ab 504 SUPERFAMILY SSF53067 4 255 2.74E-92 T 14-10-2018 MB46_04550 d98378da29b1de1c40e0193ff29443ab 504 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 262 452 1.1E-67 T 14-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 MB46_04550 d98378da29b1de1c40e0193ff29443ab 504 SUPERFAMILY SSF53067 256 499 4.48E-86 T 14-10-2018 MB46_04550 d98378da29b1de1c40e0193ff29443ab 504 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 134 146 - T 14-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 MB46_04550 d98378da29b1de1c40e0193ff29443ab 504 Gene3D G3DSA:3.30.420.40 255 504 3.5E-96 T 14-10-2018 MB46_04550 d98378da29b1de1c40e0193ff29443ab 504 Gene3D G3DSA:3.30.420.40 2 254 5.7E-112 T 14-10-2018 MB46_04550 d98378da29b1de1c40e0193ff29443ab 504 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 364 384 - T 14-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 MB46_04550 d98378da29b1de1c40e0193ff29443ab 504 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 4 253 7.4E-82 T 14-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 MB46_04550 d98378da29b1de1c40e0193ff29443ab 504 PIRSF PIRSF000538 2 503 1.4E-171 T 14-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 MB46_02325 8fcaed3b866134a98f8ae5495170dfad 319 Pfam PF00482 Type II secretion system (T2SS), protein F 152 275 3.6E-19 T 14-10-2018 IPR018076 Type II secretion system F domain MB46_02325 8fcaed3b866134a98f8ae5495170dfad 319 Gene3D G3DSA:1.20.81.30 138 254 5.5E-9 T 14-10-2018 MB46_03585 a4f833df6bcfefe86bbb74869cc88607 197 Gene3D G3DSA:1.10.10.60 13 55 7.5E-18 T 14-10-2018 MB46_03585 a4f833df6bcfefe86bbb74869cc88607 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 9.8E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MB46_03585 a4f833df6bcfefe86bbb74869cc88607 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 9.8E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MB46_03585 a4f833df6bcfefe86bbb74869cc88607 197 ProSitePatterns PS01081 TetR-type HTH domain signature. 31 62 - T 14-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site MB46_03585 a4f833df6bcfefe86bbb74869cc88607 197 Gene3D G3DSA:1.10.357.10 57 196 2.3E-33 T 14-10-2018 MB46_03585 a4f833df6bcfefe86bbb74869cc88607 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 65 1.1E-14 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MB46_03585 a4f833df6bcfefe86bbb74869cc88607 197 SUPERFAMILY SSF46689 8 87 4.16E-15 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MB46_02475 56d394f215bfb686781903f0fcaa7938 894 Gene3D G3DSA:1.10.10.10 811 886 7.0E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_02475 56d394f215bfb686781903f0fcaa7938 894 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 861 873 3.0E-8 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_02475 56d394f215bfb686781903f0fcaa7938 894 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 845 861 3.0E-8 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_02475 56d394f215bfb686781903f0fcaa7938 894 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 831 845 3.0E-8 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_02475 56d394f215bfb686781903f0fcaa7938 894 Pfam PF00196 Bacterial regulatory proteins, luxR family 830 882 2.9E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_02475 56d394f215bfb686781903f0fcaa7938 894 SMART SM00421 828 885 2.5E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_02475 56d394f215bfb686781903f0fcaa7938 894 SUPERFAMILY SSF46894 827 884 1.19E-14 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MB46_14340 6944ca0a4187cfc0493efb8eb153e43d 324 Gene3D G3DSA:3.30.390.10 17 317 3.3E-122 T 14-10-2018 IPR029017 Enolase-like, N-terminal MB46_14340 6944ca0a4187cfc0493efb8eb153e43d 324 Hamap MF_00470 o-succinylbenzoate synthase [menC]. 8 313 21.749 T 14-10-2018 IPR010196 o-Succinylbenzoate synthase, MenC type1 GO:0000287|GO:0009234|GO:0016836 KEGG: 00130+4.2.1.113|MetaCyc: PWY-5837 MB46_14340 6944ca0a4187cfc0493efb8eb153e43d 324 SMART SM00922 90 184 1.4E-15 T 14-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal MB46_14340 6944ca0a4187cfc0493efb8eb153e43d 324 Pfam PF13378 Enolase C-terminal domain-like 103 290 3.0E-28 T 14-10-2018 IPR029065 Enolase C-terminal domain-like MB46_14340 6944ca0a4187cfc0493efb8eb153e43d 324 SUPERFAMILY SSF51604 76 291 1.27E-45 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily MB46_14340 6944ca0a4187cfc0493efb8eb153e43d 324 Gene3D G3DSA:3.20.20.120 70 296 3.3E-122 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily MB46_13255 bd7e7f38e5af22f5b7f5db1d8d006c08 448 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 374 440 5.2E-12 T 14-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MB46_13255 bd7e7f38e5af22f5b7f5db1d8d006c08 448 SUPERFAMILY SSF53738 4 181 3.34E-44 T 14-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MB46_13255 bd7e7f38e5af22f5b7f5db1d8d006c08 448 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 1 445 43.616 T 14-10-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MB46_13255 bd7e7f38e5af22f5b7f5db1d8d006c08 448 Gene3D G3DSA:3.40.120.10 1 152 6.8E-44 T 14-10-2018 MB46_13255 bd7e7f38e5af22f5b7f5db1d8d006c08 448 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 258 368 9.3E-31 T 14-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MB46_13255 bd7e7f38e5af22f5b7f5db1d8d006c08 448 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 97 111 2.7E-13 T 14-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MB46_13255 bd7e7f38e5af22f5b7f5db1d8d006c08 448 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 174 193 2.7E-13 T 14-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MB46_13255 bd7e7f38e5af22f5b7f5db1d8d006c08 448 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 234 249 2.7E-13 T 14-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MB46_13255 bd7e7f38e5af22f5b7f5db1d8d006c08 448 Gene3D G3DSA:3.40.120.10 174 363 4.0E-64 T 14-10-2018 MB46_13255 bd7e7f38e5af22f5b7f5db1d8d006c08 448 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 159 254 3.0E-18 T 14-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MB46_13255 bd7e7f38e5af22f5b7f5db1d8d006c08 448 Gene3D G3DSA:3.30.310.50 371 448 1.1E-24 T 14-10-2018 MB46_13255 bd7e7f38e5af22f5b7f5db1d8d006c08 448 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 139 8.7E-40 T 14-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MB46_13255 bd7e7f38e5af22f5b7f5db1d8d006c08 448 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 5 443 1.4E-171 T 14-10-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MB46_13255 bd7e7f38e5af22f5b7f5db1d8d006c08 448 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 98 107 - T 14-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MB46_13255 bd7e7f38e5af22f5b7f5db1d8d006c08 448 Gene3D G3DSA:3.40.120.10 257 340 4.0E-64 T 14-10-2018 MB46_13255 bd7e7f38e5af22f5b7f5db1d8d006c08 448 SUPERFAMILY SSF53738 242 377 8.63E-29 T 14-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MB46_13255 bd7e7f38e5af22f5b7f5db1d8d006c08 448 SUPERFAMILY SSF55957 358 446 2.75E-22 T 14-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MB46_06120 22cfb800e5028ce5022ae91b14999319 497 Pfam PF00171 Aldehyde dehydrogenase family 28 490 5.6E-128 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 MB46_06120 22cfb800e5028ce5022ae91b14999319 497 Gene3D G3DSA:3.40.309.10 263 462 1.5E-131 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 MB46_06120 22cfb800e5028ce5022ae91b14999319 497 SUPERFAMILY SSF53720 14 495 1.7E-124 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 MB46_06120 22cfb800e5028ce5022ae91b14999319 497 Gene3D G3DSA:3.40.605.10 35 483 1.5E-131 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 MB46_03815 54b34ec0d6f7ff391cc1ecacc27c7cf0 438 Gene3D G3DSA:3.30.830.10 18 225 9.4E-65 T 14-10-2018 MB46_03815 54b34ec0d6f7ff391cc1ecacc27c7cf0 438 Pfam PF00675 Insulinase (Peptidase family M16) 28 175 2.9E-35 T 14-10-2018 IPR011765 Peptidase M16, N-terminal MB46_03815 54b34ec0d6f7ff391cc1ecacc27c7cf0 438 SUPERFAMILY SSF63411 19 221 5.41E-55 T 14-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 MB46_03815 54b34ec0d6f7ff391cc1ecacc27c7cf0 438 Gene3D G3DSA:3.30.830.10 251 435 8.2E-57 T 14-10-2018 MB46_03815 54b34ec0d6f7ff391cc1ecacc27c7cf0 438 Pfam PF05193 Peptidase M16 inactive domain 184 364 1.2E-34 T 14-10-2018 IPR007863 Peptidase M16, C-terminal MB46_03815 54b34ec0d6f7ff391cc1ecacc27c7cf0 438 SUPERFAMILY SSF63411 249 435 6.22E-48 T 14-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 MB46_03815 54b34ec0d6f7ff391cc1ecacc27c7cf0 438 ProSitePatterns PS00143 Insulinase family, zinc-binding region signature. 49 72 - T 14-10-2018 IPR001431 Peptidase M16, zinc-binding site GO:0004222|GO:0006508 MB46_07265 ff6aacedc6c0d189b11421fcb850042f 591 SUPERFAMILY SSF49785 356 576 1.06E-26 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily MB46_07265 ff6aacedc6c0d189b11421fcb850042f 591 Gene3D G3DSA:2.60.120.260 365 546 2.1E-43 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily MB46_07265 ff6aacedc6c0d189b11421fcb850042f 591 SUPERFAMILY SSF53474 37 349 7.03E-68 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_07265 ff6aacedc6c0d189b11421fcb850042f 591 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 333 573 9.6E-31 T 14-10-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 MB46_07265 ff6aacedc6c0d189b11421fcb850042f 591 Gene3D G3DSA:1.10.3020.20 212 260 1.7E-117 T 14-10-2018 MB46_07265 ff6aacedc6c0d189b11421fcb850042f 591 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 61 305 3.2E-39 T 14-10-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 MB46_07265 ff6aacedc6c0d189b11421fcb850042f 591 TIGRFAM TIGR00976 /NonD: hydrolase CocE/NonD family protein 57 221 4.5E-51 T 14-10-2018 IPR005674 CocE/Serine esterase GO:0016787 MB46_07265 ff6aacedc6c0d189b11421fcb850042f 591 SMART SM00939 321 573 5.3E-38 T 14-10-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 MB46_07265 ff6aacedc6c0d189b11421fcb850042f 591 Gene3D G3DSA:3.40.50.1820 60 345 1.7E-117 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_13130 8e45a073028d97f5ad95d62780ac2832 1011 Gene3D G3DSA:2.60.40.10 211 299 2.0E-18 T 14-10-2018 IPR013783 Immunoglobulin-like fold MB46_13130 8e45a073028d97f5ad95d62780ac2832 1011 ProSitePatterns PS00719 Glycosyl hydrolases family 2 signature 1. 351 376 - T 14-10-2018 IPR023230 Glycoside hydrolase, family 2, conserved site KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 MB46_13130 8e45a073028d97f5ad95d62780ac2832 1011 SUPERFAMILY SSF51445 301 594 4.56E-93 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily MB46_13130 8e45a073028d97f5ad95d62780ac2832 1011 Pfam PF02929 Beta galactosidase small chain 746 1006 3.0E-45 T 14-10-2018 IPR004199 Beta galactosidase small chain/ domain 5 GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 MB46_13130 8e45a073028d97f5ad95d62780ac2832 1011 Gene3D G3DSA:2.60.120.260 1 210 8.5E-75 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily MB46_13130 8e45a073028d97f5ad95d62780ac2832 1011 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 301 600 1.8E-99 T 14-10-2018 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 MB46_13130 8e45a073028d97f5ad95d62780ac2832 1011 Gene3D G3DSA:2.70.98.10 712 1011 1.7E-108 T 14-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 MB46_13130 8e45a073028d97f5ad95d62780ac2832 1011 SUPERFAMILY SSF49303 594 707 8.63E-23 T 14-10-2018 IPR036156 Beta-Galactosidase/glucuronidase domain superfamily MB46_13130 8e45a073028d97f5ad95d62780ac2832 1011 SUPERFAMILY SSF74650 730 1008 1.0E-71 T 14-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 MB46_13130 8e45a073028d97f5ad95d62780ac2832 1011 SMART SM01038 726 1009 8.4E-60 T 14-10-2018 IPR004199 Beta galactosidase small chain/ domain 5 GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 MB46_13130 8e45a073028d97f5ad95d62780ac2832 1011 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 26 210 1.8E-43 T 14-10-2018 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 MB46_13130 8e45a073028d97f5ad95d62780ac2832 1011 ProSitePatterns PS00608 Glycosyl hydrolases family 2 acid/base catalyst. 416 430 - T 14-10-2018 IPR023232 Glycoside hydrolase, family 2, active site KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 MB46_13130 8e45a073028d97f5ad95d62780ac2832 1011 Gene3D G3DSA:2.60.40.10 597 709 7.5E-24 T 14-10-2018 IPR013783 Immunoglobulin-like fold MB46_13130 8e45a073028d97f5ad95d62780ac2832 1011 Pfam PF16353 Domain of unknown function(DUF4981) 613 703 9.9E-16 T 14-10-2018 IPR032312 Beta-galactosidase, domain 4 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 MB46_13130 8e45a073028d97f5ad95d62780ac2832 1011 SUPERFAMILY SSF49303 214 300 2.93E-15 T 14-10-2018 IPR036156 Beta-Galactosidase/glucuronidase domain superfamily MB46_13130 8e45a073028d97f5ad95d62780ac2832 1011 SUPERFAMILY SSF49785 10 210 2.31E-63 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily MB46_13130 8e45a073028d97f5ad95d62780ac2832 1011 Gene3D G3DSA:3.20.20.80 300 596 8.6E-116 T 14-10-2018 MB46_13130 8e45a073028d97f5ad95d62780ac2832 1011 PRINTS PR00132 Glycosyl hydrolase family 2 signature 503 518 9.9E-33 T 14-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 MB46_13130 8e45a073028d97f5ad95d62780ac2832 1011 PRINTS PR00132 Glycosyl hydrolase family 2 signature 138 153 9.9E-33 T 14-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 MB46_13130 8e45a073028d97f5ad95d62780ac2832 1011 PRINTS PR00132 Glycosyl hydrolase family 2 signature 310 324 9.9E-33 T 14-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 MB46_13130 8e45a073028d97f5ad95d62780ac2832 1011 PRINTS PR00132 Glycosyl hydrolase family 2 signature 341 359 9.9E-33 T 14-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 MB46_13130 8e45a073028d97f5ad95d62780ac2832 1011 PRINTS PR00132 Glycosyl hydrolase family 2 signature 416 431 9.9E-33 T 14-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 MB46_19180 6cd84a9f36ad7a2af61b13ddc8693000 201 Pfam PF12724 Flavodoxin domain 8 79 4.6E-8 T 14-10-2018 IPR026816 Flavodoxin domain MB46_19180 6cd84a9f36ad7a2af61b13ddc8693000 201 SUPERFAMILY SSF52218 5 185 2.88E-41 T 14-10-2018 IPR029039 Flavoprotein-like superfamily MB46_19180 6cd84a9f36ad7a2af61b13ddc8693000 201 Gene3D G3DSA:3.40.50.360 1 190 8.9E-49 T 14-10-2018 IPR029039 Flavoprotein-like superfamily MB46_19980 6cd84a9f36ad7a2af61b13ddc8693000 201 Pfam PF12724 Flavodoxin domain 8 79 4.6E-8 T 14-10-2018 IPR026816 Flavodoxin domain MB46_19980 6cd84a9f36ad7a2af61b13ddc8693000 201 SUPERFAMILY SSF52218 5 185 2.88E-41 T 14-10-2018 IPR029039 Flavoprotein-like superfamily MB46_19980 6cd84a9f36ad7a2af61b13ddc8693000 201 Gene3D G3DSA:3.40.50.360 1 190 8.9E-49 T 14-10-2018 IPR029039 Flavoprotein-like superfamily MB46_04145 7e4218daff38fee3949ff3ef5b006219 298 TIGRFAM TIGR00761 argB: acetylglutamate kinase 28 267 6.2E-73 T 14-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 MB46_04145 7e4218daff38fee3949ff3ef5b006219 298 PRINTS PR00474 Glutamate 5-kinase family signature 58 72 6.7E-9 T 14-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 MB46_04145 7e4218daff38fee3949ff3ef5b006219 298 PRINTS PR00474 Glutamate 5-kinase family signature 243 263 6.7E-9 T 14-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 MB46_04145 7e4218daff38fee3949ff3ef5b006219 298 PRINTS PR00474 Glutamate 5-kinase family signature 192 219 6.7E-9 T 14-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 MB46_04145 7e4218daff38fee3949ff3ef5b006219 298 SUPERFAMILY SSF53633 6 295 8.77E-83 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily MB46_04145 7e4218daff38fee3949ff3ef5b006219 298 Hamap MF_00082 Acetylglutamate kinase [argB]. 26 286 45.048 T 14-10-2018 IPR037528 Acetylglutamate kinase ArgB GO:0003991|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 MB46_04145 7e4218daff38fee3949ff3ef5b006219 298 Pfam PF00696 Amino acid kinase family 28 269 2.0E-43 T 14-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 MB46_04145 7e4218daff38fee3949ff3ef5b006219 298 PIRSF PIRSF000728 12 292 4.9E-98 T 14-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 MB46_04145 7e4218daff38fee3949ff3ef5b006219 298 Gene3D G3DSA:3.40.1160.10 4 298 5.8E-96 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily MB46_01250 0baeeaee894430afc55d78afd81f4b57 235 Gene3D G3DSA:1.10.10.10 16 91 5.8E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_01250 0baeeaee894430afc55d78afd81f4b57 235 SMART SM00345 23 82 3.6E-17 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MB46_01250 0baeeaee894430afc55d78afd81f4b57 235 Pfam PF07729 FCD domain 101 220 8.7E-27 T 14-10-2018 IPR011711 GntR, C-terminal MB46_01250 0baeeaee894430afc55d78afd81f4b57 235 SUPERFAMILY SSF48008 98 222 2.88E-26 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MB46_01250 0baeeaee894430afc55d78afd81f4b57 235 SMART SM00895 100 221 7.2E-21 T 14-10-2018 IPR011711 GntR, C-terminal MB46_01250 0baeeaee894430afc55d78afd81f4b57 235 SUPERFAMILY SSF46785 16 114 1.07E-17 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_01250 0baeeaee894430afc55d78afd81f4b57 235 Gene3D G3DSA:1.20.120.530 97 231 3.9E-29 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MB46_01250 0baeeaee894430afc55d78afd81f4b57 235 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 56 72 7.3E-6 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MB46_01250 0baeeaee894430afc55d78afd81f4b57 235 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 42 56 7.3E-6 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MB46_01250 0baeeaee894430afc55d78afd81f4b57 235 Pfam PF00392 Bacterial regulatory proteins, gntR family 20 82 7.2E-16 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MB46_15130 03936f4cd241268a0986f7c3e77baa4c 400 Pfam PF01168 Alanine racemase, N-terminal domain 9 273 3.0E-6 T 14-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MB46_15130 03936f4cd241268a0986f7c3e77baa4c 400 SUPERFAMILY SSF51419 9 276 2.13E-12 T 14-10-2018 IPR029066 PLP-binding barrel MB46_15130 03936f4cd241268a0986f7c3e77baa4c 400 Gene3D G3DSA:3.20.20.10 11 272 9.8E-40 T 14-10-2018 IPR029066 PLP-binding barrel MB46_18860 3683417cf4fb6a0fd5ce358b8ba44131 326 Gene3D G3DSA:3.20.20.100 6 311 8.4E-67 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily MB46_18860 3683417cf4fb6a0fd5ce358b8ba44131 326 Pfam PF00248 Aldo/keto reductase family 12 312 3.8E-50 T 14-10-2018 IPR023210 NADP-dependent oxidoreductase domain MB46_18860 3683417cf4fb6a0fd5ce358b8ba44131 326 SUPERFAMILY SSF51430 10 313 9.82E-62 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily MB46_09850 e33a6bcdd54e92c871ca833444a971ad 559 ProSitePatterns PS01233 Urocanase signature. 444 459 - T 14-10-2018 IPR023636 Urocanase conserved site GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 MB46_09850 e33a6bcdd54e92c871ca833444a971ad 559 Pfam PF01175 Urocanase Rossmann-like domain 140 351 4.4E-80 T 14-10-2018 IPR035085 Urocanase, Rossmann-like domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 MB46_09850 e33a6bcdd54e92c871ca833444a971ad 559 TIGRFAM TIGR01228 hutU: urocanate hydratase 9 556 7.6E-274 T 14-10-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 MB46_09850 e33a6bcdd54e92c871ca833444a971ad 559 Gene3D G3DSA:3.40.50.10730 141 351 2.7E-247 T 14-10-2018 IPR038364 Urocanase, central domain superfamily KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 MB46_09850 e33a6bcdd54e92c871ca833444a971ad 559 PIRSF PIRSF001423 1 559 1.4E-275 T 14-10-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 MB46_09850 e33a6bcdd54e92c871ca833444a971ad 559 Pfam PF17392 Urocanase C-terminal domain 354 548 3.0E-94 T 14-10-2018 IPR035401 Urocanase, C-terminal domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 MB46_09850 e33a6bcdd54e92c871ca833444a971ad 559 Gene3D G3DSA:3.40.1770.10 16 544 2.7E-247 T 14-10-2018 MB46_09850 e33a6bcdd54e92c871ca833444a971ad 559 Pfam PF17391 Urocanase N-terminal domain 11 137 1.7E-59 T 14-10-2018 IPR035400 Urocanase, N-terminal domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 MB46_09850 e33a6bcdd54e92c871ca833444a971ad 559 Hamap MF_00577 Urocanate hydratase [hutU]. 4 558 49.804 T 14-10-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 MB46_09850 e33a6bcdd54e92c871ca833444a971ad 559 SUPERFAMILY SSF111326 5 557 1.06E-246 T 14-10-2018 IPR036190 Urocanase superfamily KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 MB46_04210 6d65007bc22d812dad1f659b768bd964 436 Hamap MF_02006 Tyrosine--tRNA ligase [tyrS]. 17 434 42.185 T 14-10-2018 IPR024107 Tyrosine-tRNA ligase, bacterial-type, type 1 GO:0004831 KEGG: 00970+6.1.1.1 MB46_04210 6d65007bc22d812dad1f659b768bd964 436 SUPERFAMILY SSF55174 341 433 2.35E-18 T 14-10-2018 MB46_04210 6d65007bc22d812dad1f659b768bd964 436 Gene3D G3DSA:1.10.240.10 238 339 2.2E-33 T 14-10-2018 MB46_04210 6d65007bc22d812dad1f659b768bd964 436 Pfam PF00579 tRNA synthetases class I (W and Y) 45 338 1.3E-73 T 14-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 MB46_04210 6d65007bc22d812dad1f659b768bd964 436 Gene3D G3DSA:3.10.290.10 340 435 4.3E-28 T 14-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 MB46_04210 6d65007bc22d812dad1f659b768bd964 436 SUPERFAMILY SSF52374 18 338 1.33E-92 T 14-10-2018 MB46_04210 6d65007bc22d812dad1f659b768bd964 436 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 18 433 3.5E-109 T 14-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 MB46_04210 6d65007bc22d812dad1f659b768bd964 436 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 55 65 - T 14-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 MB46_04210 6d65007bc22d812dad1f659b768bd964 436 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 177 192 9.4E-25 T 14-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 MB46_04210 6d65007bc22d812dad1f659b768bd964 436 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 198 220 9.4E-25 T 14-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 MB46_04210 6d65007bc22d812dad1f659b768bd964 436 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 231 243 9.4E-25 T 14-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 MB46_04210 6d65007bc22d812dad1f659b768bd964 436 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 59 81 9.4E-25 T 14-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 MB46_04210 6d65007bc22d812dad1f659b768bd964 436 Gene3D G3DSA:3.40.50.620 16 237 3.3E-79 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MB46_06440 694f569c41216fafd4ef617a5c3c5d1e 518 SMART SM00710 163 194 4000.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat MB46_06440 694f569c41216fafd4ef617a5c3c5d1e 518 SMART SM00710 325 346 2000.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat MB46_06440 694f569c41216fafd4ef617a5c3c5d1e 518 SMART SM00710 245 267 3.9 T 14-10-2018 IPR006626 Parallel beta-helix repeat MB46_06440 694f569c41216fafd4ef617a5c3c5d1e 518 SMART SM00710 130 157 4200.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat MB46_06440 694f569c41216fafd4ef617a5c3c5d1e 518 SMART SM00710 273 296 5000.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat MB46_06440 694f569c41216fafd4ef617a5c3c5d1e 518 SMART SM00710 406 430 3000.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat MB46_06440 694f569c41216fafd4ef617a5c3c5d1e 518 Gene3D G3DSA:2.160.20.10 42 510 1.1E-34 T 14-10-2018 IPR012334 Pectin lyase fold MB46_06440 694f569c41216fafd4ef617a5c3c5d1e 518 SUPERFAMILY SSF51126 59 447 3.97E-25 T 14-10-2018 IPR011050 Pectin lyase fold/virulence factor MB46_06100 73edce5a1e49b34b7ac56b0e866fb436 286 Gene3D G3DSA:1.10.3720.10 72 278 7.1E-21 T 14-10-2018 IPR035906 MetI-like superfamily MB46_06100 73edce5a1e49b34b7ac56b0e866fb436 286 SUPERFAMILY SSF161098 76 263 4.45E-26 T 14-10-2018 IPR035906 MetI-like superfamily MB46_06100 73edce5a1e49b34b7ac56b0e866fb436 286 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 99 282 7.8E-31 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_02185 4c23da887e5037561761621a2582ced5 222 Gene3D G3DSA:1.10.357.10 10 215 1.1E-30 T 14-10-2018 MB46_02185 4c23da887e5037561761621a2582ced5 222 SUPERFAMILY SSF46689 13 70 1.7E-13 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MB46_02185 4c23da887e5037561761621a2582ced5 222 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 66 7.6E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MB46_02185 4c23da887e5037561761621a2582ced5 222 ProSitePatterns PS01081 TetR-type HTH domain signature. 37 68 - T 14-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site MB46_09860 3128bfa0bff0993150d8d781d95a9bf1 196 SUPERFAMILY SSF48498 80 192 1.51E-21 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily MB46_09860 3128bfa0bff0993150d8d781d95a9bf1 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 63 3.6E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MB46_09860 3128bfa0bff0993150d8d781d95a9bf1 196 Pfam PF16859 Bacterial transcriptional repressor C-terminal 77 186 6.2E-27 T 14-10-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MB46_09860 3128bfa0bff0993150d8d781d95a9bf1 196 SUPERFAMILY SSF46689 9 74 8.98E-12 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MB46_09860 3128bfa0bff0993150d8d781d95a9bf1 196 Gene3D G3DSA:1.10.10.60 8 57 3.9E-21 T 14-10-2018 MB46_09860 3128bfa0bff0993150d8d781d95a9bf1 196 Gene3D G3DSA:1.10.357.10 58 196 1.2E-36 T 14-10-2018 MB46_05515 fb9616e85a1b5d977e129fa86f9591ed 163 Gene3D G3DSA:3.40.630.30 7 150 1.5E-18 T 14-10-2018 MB46_05515 fb9616e85a1b5d977e129fa86f9591ed 163 Pfam PF00583 Acetyltransferase (GNAT) family 43 135 1.3E-6 T 14-10-2018 IPR000182 GNAT domain MB46_05515 fb9616e85a1b5d977e129fa86f9591ed 163 SUPERFAMILY SSF55729 9 142 6.67E-18 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase MB46_05880 e1ae2d6c40f2c3763126c4d58f1ccad9 243 Gene3D G3DSA:1.10.150.240 25 115 4.7E-49 T 14-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 MB46_05880 e1ae2d6c40f2c3763126c4d58f1ccad9 243 Gene3D G3DSA:3.40.50.1000 16 241 4.7E-49 T 14-10-2018 IPR023214 HAD superfamily MB46_05880 e1ae2d6c40f2c3763126c4d58f1ccad9 243 SUPERFAMILY SSF56784 14 242 4.79E-37 T 14-10-2018 IPR036412 HAD-like superfamily MB46_05880 e1ae2d6c40f2c3763126c4d58f1ccad9 243 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 106 216 4.1E-13 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MB46_05880 e1ae2d6c40f2c3763126c4d58f1ccad9 243 Pfam PF13419 Haloacid dehalogenase-like hydrolase 16 209 1.8E-14 T 14-10-2018 MB46_08625 d88d31bebe0c8c5304131d6a0d83d21f 448 PIRSF PIRSF001549 1 444 5.4E-101 T 14-10-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 MB46_08625 d88d31bebe0c8c5304131d6a0d83d21f 448 Gene3D G3DSA:3.40.50.800 352 445 2.2E-17 T 14-10-2018 IPR036621 Anticodon-binding domain superfamily MB46_08625 d88d31bebe0c8c5304131d6a0d83d21f 448 Pfam PF03129 Anticodon binding domain 358 427 2.1E-8 T 14-10-2018 IPR004154 Anticodon-binding MB46_08625 d88d31bebe0c8c5304131d6a0d83d21f 448 SUPERFAMILY SSF52954 353 430 1.05E-15 T 14-10-2018 MB46_08625 d88d31bebe0c8c5304131d6a0d83d21f 448 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 6 428 7.5E-110 T 14-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 MB46_08625 d88d31bebe0c8c5304131d6a0d83d21f 448 Pfam PF13393 Histidyl-tRNA synthetase 9 336 7.1E-28 T 14-10-2018 MB46_08625 d88d31bebe0c8c5304131d6a0d83d21f 448 Gene3D G3DSA:3.30.930.10 3 351 9.9E-88 T 14-10-2018 MB46_08625 d88d31bebe0c8c5304131d6a0d83d21f 448 SUPERFAMILY SSF55681 7 344 7.05E-62 T 14-10-2018 MB46_15185 b2574c694051e996f683c299dbf52c63 281 Pfam PF09339 IclR helix-turn-helix domain 30 77 1.4E-9 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 MB46_15185 b2574c694051e996f683c299dbf52c63 281 Pfam PF01614 Bacterial transcriptional regulator 147 273 4.8E-19 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal MB46_15185 b2574c694051e996f683c299dbf52c63 281 Gene3D G3DSA:1.10.10.10 26 102 2.2E-16 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_15185 b2574c694051e996f683c299dbf52c63 281 SMART SM00346 28 118 6.2E-10 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 MB46_15185 b2574c694051e996f683c299dbf52c63 281 Gene3D G3DSA:3.30.450.40 104 279 1.5E-43 T 14-10-2018 IPR029016 GAF-like domain superfamily MB46_15185 b2574c694051e996f683c299dbf52c63 281 SUPERFAMILY SSF46785 28 101 8.2E-14 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_15185 b2574c694051e996f683c299dbf52c63 281 SUPERFAMILY SSF55781 93 275 2.68E-38 T 14-10-2018 MB46_06970 69241885b300eb0518b3e5bdcec7aa5f 278 Gene3D G3DSA:3.40.50.1820 22 278 3.2E-43 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_06970 69241885b300eb0518b3e5bdcec7aa5f 278 Pfam PF00756 Putative esterase 49 243 2.1E-12 T 14-10-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 MB46_06970 69241885b300eb0518b3e5bdcec7aa5f 278 SUPERFAMILY SSF53474 26 278 2.6E-31 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_05540 69241885b300eb0518b3e5bdcec7aa5f 278 Gene3D G3DSA:3.40.50.1820 22 278 3.2E-43 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_05540 69241885b300eb0518b3e5bdcec7aa5f 278 Pfam PF00756 Putative esterase 49 243 2.1E-12 T 14-10-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 MB46_05540 69241885b300eb0518b3e5bdcec7aa5f 278 SUPERFAMILY SSF53474 26 278 2.6E-31 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_04015 dc4ddeb81f964927154c4105ad0e1bbe 302 Gene3D G3DSA:3.30.1330.30 10 121 1.8E-9 T 14-10-2018 IPR029064 50S ribosomal protein L30e-like MB46_04015 dc4ddeb81f964927154c4105ad0e1bbe 302 SUPERFAMILY SSF55315 12 121 2.0E-14 T 14-10-2018 IPR029064 50S ribosomal protein L30e-like MB46_04015 dc4ddeb81f964927154c4105ad0e1bbe 302 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 39 119 2.3E-7 T 14-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 MB46_04015 dc4ddeb81f964927154c4105ad0e1bbe 302 SUPERFAMILY SSF75217 112 300 2.62E-35 T 14-10-2018 IPR029028 Alpha/beta knot methyltransferases MB46_04015 dc4ddeb81f964927154c4105ad0e1bbe 302 Pfam PF00588 SpoU rRNA Methylase family 135 293 2.8E-30 T 14-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 MB46_04015 dc4ddeb81f964927154c4105ad0e1bbe 302 Gene3D G3DSA:3.40.1280.10 125 302 1.1E-46 T 14-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal MB46_04015 dc4ddeb81f964927154c4105ad0e1bbe 302 SMART SM00967 39 124 3.6E-10 T 14-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 MB46_11735 d3a11d1e518b2712f4a3c73064294bb2 190 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 15 190 29.592 T 14-10-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 MB46_11735 d3a11d1e518b2712f4a3c73064294bb2 190 Gene3D G3DSA:3.30.1130.10 61 190 2.0E-48 T 14-10-2018 MB46_11735 d3a11d1e518b2712f4a3c73064294bb2 190 Pfam PF01227 GTP cyclohydrolase I 20 188 2.3E-57 T 14-10-2018 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 MB46_11735 d3a11d1e518b2712f4a3c73064294bb2 190 SUPERFAMILY SSF55620 10 188 3.85E-61 T 14-10-2018 MB46_11735 d3a11d1e518b2712f4a3c73064294bb2 190 Gene3D G3DSA:1.10.286.10 8 55 7.9E-11 T 14-10-2018 MB46_06260 ef8a6001b6c82ad8839d86c03cf1d2cd 133 Gene3D G3DSA:3.10.180.10 8 132 1.0E-23 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MB46_06260 ef8a6001b6c82ad8839d86c03cf1d2cd 133 SUPERFAMILY SSF54593 4 131 1.51E-16 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MB46_16795 2339f93135965b560c07366fb857ff9a 258 Gene3D G3DSA:3.40.50.620 1 253 2.3E-76 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MB46_16795 2339f93135965b560c07366fb857ff9a 258 SMART SM00893 23 213 8.6E-40 T 14-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 MB46_16795 2339f93135965b560c07366fb857ff9a 258 PIRSF PIRSF000090 1 258 1.7E-68 T 14-10-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 MB46_16795 2339f93135965b560c07366fb857ff9a 258 SUPERFAMILY SSF52402 1 252 6.14E-64 T 14-10-2018 MB46_16795 2339f93135965b560c07366fb857ff9a 258 Pfam PF01012 Electron transfer flavoprotein domain 26 208 1.6E-37 T 14-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 MB46_11980 cf187058b51ff2f3c5ef1686e46079d8 404 Gene3D G3DSA:3.90.1200.10 107 301 9.6E-36 T 14-10-2018 MB46_11980 cf187058b51ff2f3c5ef1686e46079d8 404 SUPERFAMILY SSF56112 36 272 1.53E-27 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily MB46_11980 cf187058b51ff2f3c5ef1686e46079d8 404 Pfam PF01636 Phosphotransferase enzyme family 38 257 1.3E-22 T 14-10-2018 IPR002575 Aminoglycoside phosphotransferase MB46_01390 c2de9189df3412accb26f3d4371b5546 373 SUPERFAMILY SSF53822 42 359 4.71E-66 T 14-10-2018 IPR028082 Periplasmic binding protein-like I MB46_01390 c2de9189df3412accb26f3d4371b5546 373 Gene3D G3DSA:3.40.50.2300 43 347 7.2E-126 T 14-10-2018 MB46_01390 c2de9189df3412accb26f3d4371b5546 373 Pfam PF13407 Periplasmic binding protein domain 43 325 8.0E-65 T 14-10-2018 IPR025997 Periplasmic binding protein MB46_01390 c2de9189df3412accb26f3d4371b5546 373 Gene3D G3DSA:3.40.50.2300 145 368 7.2E-126 T 14-10-2018 MB46_03085 1723eee4ac6069ad5da384d7d2a81f62 389 Gene3D G3DSA:3.30.360.10 121 366 6.6E-36 T 14-10-2018 MB46_03085 1723eee4ac6069ad5da384d7d2a81f62 389 Gene3D G3DSA:3.40.50.720 1 120 1.4E-24 T 14-10-2018 MB46_03085 1723eee4ac6069ad5da384d7d2a81f62 389 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 1 119 5.1E-17 T 14-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 MB46_03085 1723eee4ac6069ad5da384d7d2a81f62 389 SUPERFAMILY SSF55347 125 296 1.36E-26 T 14-10-2018 MB46_03085 1723eee4ac6069ad5da384d7d2a81f62 389 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 131 215 3.7E-11 T 14-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 MB46_03085 1723eee4ac6069ad5da384d7d2a81f62 389 SUPERFAMILY SSF51735 2 147 3.54E-38 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_15655 f6ee711dc7d9981a8e0c357c84aa940b 367 SMART SM00954 57 202 6.3E-12 T 14-10-2018 IPR007685 RelA/SpoT GO:0015969 MB46_15655 f6ee711dc7d9981a8e0c357c84aa940b 367 SUPERFAMILY SSF81301 32 232 9.32E-25 T 14-10-2018 MB46_15655 f6ee711dc7d9981a8e0c357c84aa940b 367 Pfam PF04607 Region found in RelA / SpoT proteins 57 199 2.1E-15 T 14-10-2018 IPR007685 RelA/SpoT GO:0015969 MB46_15655 f6ee711dc7d9981a8e0c357c84aa940b 367 Gene3D G3DSA:3.30.460.10 16 183 1.4E-14 T 14-10-2018 MB46_09030 c47ca6ed9b411f01c95efeced5d98942 447 Gene3D G3DSA:3.40.50.720 1 197 5.3E-62 T 14-10-2018 MB46_09030 c47ca6ed9b411f01c95efeced5d98942 447 SUPERFAMILY SSF51735 1 188 2.1E-45 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_09030 c47ca6ed9b411f01c95efeced5d98942 447 SUPERFAMILY SSF48179 200 280 8.5E-23 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MB46_09030 c47ca6ed9b411f01c95efeced5d98942 447 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 201 294 1.7E-27 T 14-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 MB46_09030 c47ca6ed9b411f01c95efeced5d98942 447 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 1 415 4.2E-111 T 14-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 MB46_09030 c47ca6ed9b411f01c95efeced5d98942 447 Gene3D G3DSA:3.40.50.720 231 446 3.3E-60 T 14-10-2018 MB46_09030 c47ca6ed9b411f01c95efeced5d98942 447 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 1 171 1.4E-49 T 14-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 MB46_09030 c47ca6ed9b411f01c95efeced5d98942 447 SUPERFAMILY SSF52413 309 429 7.72E-31 T 14-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 MB46_09030 c47ca6ed9b411f01c95efeced5d98942 447 PIRSF PIRSF000124 1 434 2.7E-111 T 14-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 MB46_09030 c47ca6ed9b411f01c95efeced5d98942 447 SMART SM00984 318 419 1.1E-32 T 14-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 MB46_09030 c47ca6ed9b411f01c95efeced5d98942 447 PIRSF PIRSF500134 1 437 2.3E-132 T 14-10-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 MB46_09030 c47ca6ed9b411f01c95efeced5d98942 447 Gene3D G3DSA:1.20.5.100 200 229 3.9E-11 T 14-10-2018 MB46_09030 c47ca6ed9b411f01c95efeced5d98942 447 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 318 418 8.3E-25 T 14-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 MB46_03145 3d88afe7dbb94a831af9b9ba92e8c896 283 Pfam PF01116 Fructose-bisphosphate aldolase class-II 5 276 1.2E-79 T 14-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 MB46_03145 3d88afe7dbb94a831af9b9ba92e8c896 283 PIRSF PIRSF001359 1 280 1.3E-69 T 14-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 MB46_03145 3d88afe7dbb94a831af9b9ba92e8c896 283 Gene3D G3DSA:3.20.20.70 1 282 1.5E-86 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MB46_03145 3d88afe7dbb94a831af9b9ba92e8c896 283 SUPERFAMILY SSF51569 3 278 2.64E-80 T 14-10-2018 MB46_03145 3d88afe7dbb94a831af9b9ba92e8c896 283 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 1 275 4.6E-67 T 14-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 MB46_08695 5828b6e0980585c457a05d5f58aca4e9 674 Pfam PF01432 Peptidase family M3 233 672 2.0E-103 T 14-10-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 MB46_08695 5828b6e0980585c457a05d5f58aca4e9 674 Gene3D G3DSA:1.10.1370.10 145 605 2.3E-220 T 14-10-2018 IPR024077 Neurolysin/Thimet oligopeptidase, domain 2 MB46_08695 5828b6e0980585c457a05d5f58aca4e9 674 Gene3D G3DSA:1.10.1370.40 41 669 2.3E-220 T 14-10-2018 MB46_08695 5828b6e0980585c457a05d5f58aca4e9 674 SUPERFAMILY SSF55486 16 672 6.87E-147 T 14-10-2018 MB46_05020 f079d8cddea369752fb57c2c9f4b5004 962 Pfam PF00005 ABC transporter 645 880 9.4E-11 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_05020 f079d8cddea369752fb57c2c9f4b5004 962 SMART SM00382 653 942 0.0016 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_05020 f079d8cddea369752fb57c2c9f4b5004 962 ProSitePatterns PS00211 ABC transporters family signature. 508 522 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_05020 f079d8cddea369752fb57c2c9f4b5004 962 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 19 945 0.0 T 14-10-2018 IPR004602 UvrABC system subunit A GO:0003677|GO:0006289|GO:0009380|GO:0016887 MB46_05020 f079d8cddea369752fb57c2c9f4b5004 962 Hamap MF_00205 UvrABC system protein A [uvrA]. 16 960 22.573 T 14-10-2018 IPR004602 UvrABC system subunit A GO:0003677|GO:0006289|GO:0009380|GO:0016887 MB46_05020 f079d8cddea369752fb57c2c9f4b5004 962 Gene3D G3DSA:3.40.50.300 637 956 6.5E-142 T 14-10-2018 MB46_05020 f079d8cddea369752fb57c2c9f4b5004 962 Gene3D G3DSA:3.30.190.20 145 257 4.4E-256 T 14-10-2018 MB46_05020 f079d8cddea369752fb57c2c9f4b5004 962 ProSitePatterns PS00211 ABC transporters family signature. 850 864 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_05020 f079d8cddea369752fb57c2c9f4b5004 962 Gene3D G3DSA:1.20.1580.10 105 513 4.4E-256 T 14-10-2018 MB46_05020 f079d8cddea369752fb57c2c9f4b5004 962 Gene3D G3DSA:3.40.50.300 20 616 4.4E-256 T 14-10-2018 MB46_05020 f079d8cddea369752fb57c2c9f4b5004 962 SUPERFAMILY SSF52540 640 933 7.52E-49 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_05020 f079d8cddea369752fb57c2c9f4b5004 962 Gene3D G3DSA:1.10.8.280 306 424 4.4E-256 T 14-10-2018 MB46_05020 f079d8cddea369752fb57c2c9f4b5004 962 Gene3D G3DSA:1.20.1580.10 712 850 6.5E-142 T 14-10-2018 MB46_05020 f079d8cddea369752fb57c2c9f4b5004 962 SUPERFAMILY SSF52540 25 590 2.01E-44 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_04770 01831f585f8c888e2a74a9a85eb29d4c 157 PIRSF PIRSF021700 1 157 9.2E-61 T 14-10-2018 IPR009725 Predicted 3-demethylubiquinone-9 3-methyltransferase MB46_04770 01831f585f8c888e2a74a9a85eb29d4c 157 SUPERFAMILY SSF54593 4 156 3.66E-46 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MB46_04770 01831f585f8c888e2a74a9a85eb29d4c 157 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 4 117 3.7E-45 T 14-10-2018 IPR028973 PhnB-like MB46_04770 01831f585f8c888e2a74a9a85eb29d4c 157 Gene3D G3DSA:3.10.180.70 2 157 8.1E-62 T 14-10-2018 MB46_12805 6eb4dafc5a89622591944480d3417767 528 SUPERFAMILY SSF52540 318 517 3.82E-45 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_12805 6eb4dafc5a89622591944480d3417767 528 Pfam PF00005 ABC transporter 342 474 6.2E-23 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_12805 6eb4dafc5a89622591944480d3417767 528 SUPERFAMILY SSF52540 4 238 9.94E-42 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_12805 6eb4dafc5a89622591944480d3417767 528 ProSitePatterns PS00211 ABC transporters family signature. 446 460 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_12805 6eb4dafc5a89622591944480d3417767 528 SMART SM00382 349 519 9.8E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_12805 6eb4dafc5a89622591944480d3417767 528 SMART SM00382 28 237 1.1E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_12805 6eb4dafc5a89622591944480d3417767 528 ProSitePatterns PS00211 ABC transporters family signature. 164 178 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_12805 6eb4dafc5a89622591944480d3417767 528 Pfam PF00005 ABC transporter 22 192 8.0E-25 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_12805 6eb4dafc5a89622591944480d3417767 528 Gene3D G3DSA:3.40.50.300 2 302 8.1E-59 T 14-10-2018 MB46_12805 6eb4dafc5a89622591944480d3417767 528 Pfam PF12848 ABC transporter 231 304 7.9E-6 T 14-10-2018 IPR032781 ABC-transporter extension domain MB46_12805 6eb4dafc5a89622591944480d3417767 528 Gene3D G3DSA:3.40.50.300 318 526 6.3E-49 T 14-10-2018 MB46_10930 dab0195100124239ea140d75059e0813 755 Pfam PF07498 Rho termination factor, N-terminal domain 29 62 6.0E-7 T 14-10-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 MB46_10930 dab0195100124239ea140d75059e0813 755 SMART SM00382 496 681 4.1E-8 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_10930 dab0195100124239ea140d75059e0813 755 SMART SM00357 374 435 1.4E-6 T 14-10-2018 IPR011129 Cold shock domain GO:0003676 MB46_10930 dab0195100124239ea140d75059e0813 755 Pfam PF07497 Rho termination factor, RNA-binding domain 373 454 2.0E-28 T 14-10-2018 IPR011113 Rho termination factor, RNA-binding domain GO:0003723|GO:0006353 MB46_10930 dab0195100124239ea140d75059e0813 755 Gene3D G3DSA:3.40.50.300 459 748 3.3E-120 T 14-10-2018 MB46_10930 dab0195100124239ea140d75059e0813 755 Hamap MF_01884 Transcription termination factor Rho [rho]. 365 745 192.762 T 14-10-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 MB46_10930 dab0195100124239ea140d75059e0813 755 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 484 689 2.2E-20 T 14-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 MB46_10930 dab0195100124239ea140d75059e0813 755 SUPERFAMILY SSF52540 411 697 8.6E-67 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_10930 dab0195100124239ea140d75059e0813 755 SUPERFAMILY SSF50249 373 454 5.48E-16 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold MB46_10930 dab0195100124239ea140d75059e0813 755 SMART SM00959 28 67 7.4E-6 T 14-10-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 MB46_10930 dab0195100124239ea140d75059e0813 755 TIGRFAM TIGR00767 rho: transcription termination factor Rho 29 743 3.4E-184 T 14-10-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 MB46_18630 25bd825ab8c5581af23bf35500631745 259 Gene3D G3DSA:1.20.1290.30 153 248 5.2E-8 T 14-10-2018 IPR037210 YoaC-like superfamily MB46_04950 32559bde998ae308ac5ccd36d89cb3f6 493 PRINTS PR00681 Ribosomal protein S1 signature 40 58 8.3E-86 T 14-10-2018 MB46_04950 32559bde998ae308ac5ccd36d89cb3f6 493 PRINTS PR00681 Ribosomal protein S1 signature 176 196 8.3E-86 T 14-10-2018 MB46_04950 32559bde998ae308ac5ccd36d89cb3f6 493 PRINTS PR00681 Ribosomal protein S1 signature 233 254 8.3E-86 T 14-10-2018 MB46_04950 32559bde998ae308ac5ccd36d89cb3f6 493 PRINTS PR00681 Ribosomal protein S1 signature 130 146 8.3E-86 T 14-10-2018 MB46_04950 32559bde998ae308ac5ccd36d89cb3f6 493 PRINTS PR00681 Ribosomal protein S1 signature 147 164 8.3E-86 T 14-10-2018 MB46_04950 32559bde998ae308ac5ccd36d89cb3f6 493 PRINTS PR00681 Ribosomal protein S1 signature 106 125 8.3E-86 T 14-10-2018 MB46_04950 32559bde998ae308ac5ccd36d89cb3f6 493 PRINTS PR00681 Ribosomal protein S1 signature 350 368 8.3E-86 T 14-10-2018 MB46_04950 32559bde998ae308ac5ccd36d89cb3f6 493 PRINTS PR00681 Ribosomal protein S1 signature 311 330 8.3E-86 T 14-10-2018 MB46_04950 32559bde998ae308ac5ccd36d89cb3f6 493 PRINTS PR00681 Ribosomal protein S1 signature 58 72 8.3E-86 T 14-10-2018 MB46_04950 32559bde998ae308ac5ccd36d89cb3f6 493 Gene3D G3DSA:2.40.50.140 288 371 3.9E-28 T 14-10-2018 MB46_04950 32559bde998ae308ac5ccd36d89cb3f6 493 SUPERFAMILY SSF50249 32 134 3.83E-21 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold MB46_04950 32559bde998ae308ac5ccd36d89cb3f6 493 SMART SM00316 125 192 1.3E-10 T 14-10-2018 IPR022967 RNA-binding domain, S1 MB46_04950 32559bde998ae308ac5ccd36d89cb3f6 493 SMART SM00316 296 367 4.3E-24 T 14-10-2018 IPR022967 RNA-binding domain, S1 MB46_04950 32559bde998ae308ac5ccd36d89cb3f6 493 SMART SM00316 38 109 1.7E-14 T 14-10-2018 IPR022967 RNA-binding domain, S1 MB46_04950 32559bde998ae308ac5ccd36d89cb3f6 493 SMART SM00316 211 281 1.9E-27 T 14-10-2018 IPR022967 RNA-binding domain, S1 MB46_04950 32559bde998ae308ac5ccd36d89cb3f6 493 SUPERFAMILY SSF50249 210 293 3.05E-27 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold MB46_04950 32559bde998ae308ac5ccd36d89cb3f6 493 SUPERFAMILY SSF50249 111 195 1.79E-14 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold MB46_04950 32559bde998ae308ac5ccd36d89cb3f6 493 SUPERFAMILY SSF50249 281 369 1.99E-25 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold MB46_04950 32559bde998ae308ac5ccd36d89cb3f6 493 Pfam PF00575 S1 RNA binding domain 209 281 2.6E-25 T 14-10-2018 IPR003029 S1 domain GO:0003676 MB46_04950 32559bde998ae308ac5ccd36d89cb3f6 493 Pfam PF00575 S1 RNA binding domain 37 109 2.6E-14 T 14-10-2018 IPR003029 S1 domain GO:0003676 MB46_04950 32559bde998ae308ac5ccd36d89cb3f6 493 Pfam PF00575 S1 RNA binding domain 125 192 1.2E-13 T 14-10-2018 IPR003029 S1 domain GO:0003676 MB46_04950 32559bde998ae308ac5ccd36d89cb3f6 493 Pfam PF00575 S1 RNA binding domain 295 367 1.7E-20 T 14-10-2018 IPR003029 S1 domain GO:0003676 MB46_04950 32559bde998ae308ac5ccd36d89cb3f6 493 Gene3D G3DSA:2.40.50.140 122 203 3.4E-11 T 14-10-2018 MB46_04950 32559bde998ae308ac5ccd36d89cb3f6 493 Gene3D G3DSA:2.40.50.140 28 121 9.5E-22 T 14-10-2018 MB46_04950 32559bde998ae308ac5ccd36d89cb3f6 493 Gene3D G3DSA:2.40.50.140 208 287 6.0E-30 T 14-10-2018 MB46_18810 e48709c3b88a36bda1f5bd55111de79a 390 SUPERFAMILY SSF52343 255 381 2.1E-24 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain MB46_18810 e48709c3b88a36bda1f5bd55111de79a 390 Pfam PF00175 Oxidoreductase NAD-binding domain 266 361 8.9E-5 T 14-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 MB46_18810 e48709c3b88a36bda1f5bd55111de79a 390 Gene3D G3DSA:1.10.490.10 1 147 7.1E-43 T 14-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 MB46_18810 e48709c3b88a36bda1f5bd55111de79a 390 Gene3D G3DSA:2.40.30.10 151 253 2.0E-21 T 14-10-2018 MB46_18810 e48709c3b88a36bda1f5bd55111de79a 390 Pfam PF00970 Oxidoreductase FAD-binding domain 157 253 1.5E-7 T 14-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 MB46_18810 e48709c3b88a36bda1f5bd55111de79a 390 SUPERFAMILY SSF63380 151 252 6.27E-22 T 14-10-2018 IPR017938 Riboflavin synthase-like beta-barrel MB46_18810 e48709c3b88a36bda1f5bd55111de79a 390 Gene3D G3DSA:3.40.50.80 254 383 4.9E-21 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain MB46_18810 e48709c3b88a36bda1f5bd55111de79a 390 SUPERFAMILY SSF46458 1 148 1.63E-29 T 14-10-2018 IPR009050 Globin-like superfamily MB46_18810 e48709c3b88a36bda1f5bd55111de79a 390 Pfam PF00042 Globin 9 103 2.2E-7 T 14-10-2018 IPR000971 Globin GO:0020037 MB46_18810 e48709c3b88a36bda1f5bd55111de79a 390 PRINTS PR00409 Phthalate dioxygenase reductase family signature 262 281 3.3E-6 T 14-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 MB46_18810 e48709c3b88a36bda1f5bd55111de79a 390 PRINTS PR00409 Phthalate dioxygenase reductase family signature 190 202 3.3E-6 T 14-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 MB46_18810 e48709c3b88a36bda1f5bd55111de79a 390 PRINTS PR00409 Phthalate dioxygenase reductase family signature 347 355 3.3E-6 T 14-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 MB46_18810 e48709c3b88a36bda1f5bd55111de79a 390 PRINTS PR00409 Phthalate dioxygenase reductase family signature 227 241 3.3E-6 T 14-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 MB46_15940 16edbd00cbba54e95c9c944ac474c81f 375 Pfam PF08402 TOBE domain 289 368 2.6E-8 T 14-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 MB46_15940 16edbd00cbba54e95c9c944ac474c81f 375 Gene3D G3DSA:2.40.50.140 256 291 2.5E-6 T 14-10-2018 MB46_15940 16edbd00cbba54e95c9c944ac474c81f 375 Gene3D G3DSA:3.40.50.300 6 247 1.2E-77 T 14-10-2018 MB46_15940 16edbd00cbba54e95c9c944ac474c81f 375 SUPERFAMILY SSF50331 255 368 6.56E-13 T 14-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal MB46_15940 16edbd00cbba54e95c9c944ac474c81f 375 SUPERFAMILY SSF52540 12 248 2.06E-80 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_15940 16edbd00cbba54e95c9c944ac474c81f 375 Gene3D G3DSA:2.40.50.100 292 342 2.5E-6 T 14-10-2018 MB46_15940 16edbd00cbba54e95c9c944ac474c81f 375 Pfam PF00005 ABC transporter 27 169 3.0E-35 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_15940 16edbd00cbba54e95c9c944ac474c81f 375 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_15940 16edbd00cbba54e95c9c944ac474c81f 375 SMART SM00382 36 220 2.7E-19 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_11820 b6336c7e3cf980f3f8b83eb888af2a94 291 SMART SM00530 10 80 7.6E-8 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MB46_11820 b6336c7e3cf980f3f8b83eb888af2a94 291 Gene3D G3DSA:3.30.450.180 104 271 1.8E-14 T 14-10-2018 MB46_11820 b6336c7e3cf980f3f8b83eb888af2a94 291 SUPERFAMILY SSF47413 28 78 4.74E-8 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MB46_11820 b6336c7e3cf980f3f8b83eb888af2a94 291 Pfam PF13560 Helix-turn-helix domain 6 83 2.3E-17 T 14-10-2018 MB46_11820 b6336c7e3cf980f3f8b83eb888af2a94 291 Gene3D G3DSA:1.10.260.40 23 79 2.1E-7 T 14-10-2018 MB46_17615 ead0d83929543868cc1552069dcd5fcf 419 Pfam PF01266 FAD dependent oxidoreductase 9 400 5.3E-58 T 14-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 MB46_17615 ead0d83929543868cc1552069dcd5fcf 419 Gene3D G3DSA:3.30.9.10 146 363 4.2E-39 T 14-10-2018 MB46_17615 ead0d83929543868cc1552069dcd5fcf 419 SUPERFAMILY SSF54373 277 363 6.41E-11 T 14-10-2018 MB46_17615 ead0d83929543868cc1552069dcd5fcf 419 SUPERFAMILY SSF51971 7 405 1.65E-41 T 14-10-2018 MB46_17615 ead0d83929543868cc1552069dcd5fcf 419 Gene3D G3DSA:3.50.50.60 202 401 4.2E-39 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_17615 ead0d83929543868cc1552069dcd5fcf 419 Gene3D G3DSA:3.50.50.60 7 78 3.8E-19 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_02795 9ffec219ab490f7ef12e53e56b4de24a 102 SUPERFAMILY SSF46785 5 97 5.46E-12 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_02795 9ffec219ab490f7ef12e53e56b4de24a 102 Pfam PF13601 Winged helix DNA-binding domain 21 97 2.7E-24 T 14-10-2018 IPR027395 Winged helix DNA-binding domain MB46_02795 9ffec219ab490f7ef12e53e56b4de24a 102 Gene3D G3DSA:1.10.10.10 10 101 4.3E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_04575 be45940e96e378b64496cfc08b1758ad 321 TIGRFAM TIGR01128 holA: DNA polymerase III, delta subunit 8 313 9.6E-33 T 14-10-2018 IPR005790 DNA polymerase III, delta subunit GO:0003677|GO:0006260 MB46_04575 be45940e96e378b64496cfc08b1758ad 321 Pfam PF06144 DNA polymerase III, delta subunit 13 172 2.0E-8 T 14-10-2018 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 MB46_04575 be45940e96e378b64496cfc08b1758ad 321 Gene3D G3DSA:3.40.50.300 3 121 1.3E-11 T 14-10-2018 MB46_04575 be45940e96e378b64496cfc08b1758ad 321 Gene3D G3DSA:1.20.272.10 197 320 4.6E-21 T 14-10-2018 MB46_04575 be45940e96e378b64496cfc08b1758ad 321 SUPERFAMILY SSF48019 200 316 4.68E-21 T 14-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 MB46_03890 3ec92b04de774a87728955a0fb5b7ee5 203 Pfam PF01066 CDP-alcohol phosphatidyltransferase 13 83 4.2E-15 T 14-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 MB46_03890 3ec92b04de774a87728955a0fb5b7ee5 203 Gene3D G3DSA:1.20.120.1760 1 184 3.4E-12 T 14-10-2018 MB46_03890 3ec92b04de774a87728955a0fb5b7ee5 203 PIRSF PIRSF000847 9 196 9.5E-44 T 14-10-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 MB46_03890 3ec92b04de774a87728955a0fb5b7ee5 203 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 61 83 - T 14-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 MB46_03890 3ec92b04de774a87728955a0fb5b7ee5 203 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 13 187 2.4E-36 T 14-10-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 MB46_03955 294134ffecea5c3f534348430434ef38 247 Pfam PF01726 LexA DNA binding domain 19 83 3.3E-25 T 14-10-2018 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 MB46_03955 294134ffecea5c3f534348430434ef38 247 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 163 173 2.5E-10 T 14-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 MB46_03955 294134ffecea5c3f534348430434ef38 247 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 202 214 2.5E-10 T 14-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 MB46_03955 294134ffecea5c3f534348430434ef38 247 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 174 185 2.5E-10 T 14-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 MB46_03955 294134ffecea5c3f534348430434ef38 247 Hamap MF_00015 LexA repressor [lexA]. 21 247 31.648 T 14-10-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 MB46_03955 294134ffecea5c3f534348430434ef38 247 SUPERFAMILY SSF46785 21 87 1.34E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_03955 294134ffecea5c3f534348430434ef38 247 Pfam PF00717 Peptidase S24-like 166 229 4.5E-14 T 14-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C MB46_03955 294134ffecea5c3f534348430434ef38 247 Gene3D G3DSA:2.10.109.10 132 247 8.5E-40 T 14-10-2018 MB46_03955 294134ffecea5c3f534348430434ef38 247 TIGRFAM TIGR00498 lexA: repressor LexA 19 246 2.1E-68 T 14-10-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 MB46_03955 294134ffecea5c3f534348430434ef38 247 SUPERFAMILY SSF51306 127 245 4.01E-34 T 14-10-2018 IPR036286 LexA/Signal peptidase-like superfamily MB46_03955 294134ffecea5c3f534348430434ef38 247 Gene3D G3DSA:1.10.10.10 21 86 2.0E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_19785 19d6898f7477eea3d605f8e6202c5f68 134 Pfam PF00072 Response regulator receiver domain 8 114 4.6E-20 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MB46_19785 19d6898f7477eea3d605f8e6202c5f68 134 SMART SM00448 5 115 1.3E-27 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MB46_19785 19d6898f7477eea3d605f8e6202c5f68 134 Gene3D G3DSA:3.40.50.12740 7 131 9.3E-28 T 14-10-2018 MB46_19785 19d6898f7477eea3d605f8e6202c5f68 134 SUPERFAMILY SSF52172 7 120 6.83E-29 T 14-10-2018 IPR011006 CheY-like superfamily MB46_17480 78d5acbeaec53b3d5cc50e4b9fde5e11 415 Gene3D G3DSA:3.40.630.10 24 393 1.2E-104 T 14-10-2018 MB46_17480 78d5acbeaec53b3d5cc50e4b9fde5e11 415 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 23 398 8.8E-81 T 14-10-2018 IPR017439 Amidohydrolase GO:0016787 MB46_17480 78d5acbeaec53b3d5cc50e4b9fde5e11 415 Pfam PF01546 Peptidase family M20/M25/M40 80 368 2.3E-19 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 MB46_17480 78d5acbeaec53b3d5cc50e4b9fde5e11 415 SUPERFAMILY SSF53187 14 401 1.54E-69 T 14-10-2018 MB46_17480 78d5acbeaec53b3d5cc50e4b9fde5e11 415 SUPERFAMILY SSF55031 201 302 2.22E-28 T 14-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain MB46_17480 78d5acbeaec53b3d5cc50e4b9fde5e11 415 Pfam PF07687 Peptidase dimerisation domain 202 298 1.7E-16 T 14-10-2018 IPR011650 Peptidase M20, dimerisation domain MB46_17480 78d5acbeaec53b3d5cc50e4b9fde5e11 415 PIRSF PIRSF005962 9 408 9.6E-93 T 14-10-2018 IPR017439 Amidohydrolase GO:0016787 MB46_17480 78d5acbeaec53b3d5cc50e4b9fde5e11 415 Gene3D G3DSA:3.30.70.360 198 313 1.2E-104 T 14-10-2018 MB46_08955 f371a3bbcd541c6c37931688d18834e9 537 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 4 342 1.6E-114 T 14-10-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 MB46_08955 f371a3bbcd541c6c37931688d18834e9 537 Gene3D G3DSA:2.40.240.60 375 448 6.1E-18 T 14-10-2018 IPR036346 GTP-binding protein OBG, C-terminal domain superfamily MB46_08955 f371a3bbcd541c6c37931688d18834e9 537 TIGRFAM TIGR03595 Obg_CgtA_exten: Obg family GTPase CgtA, C-terminal extension 371 446 4.0E-25 T 14-10-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 MB46_08955 f371a3bbcd541c6c37931688d18834e9 537 SUPERFAMILY SSF102741 370 447 3.66E-18 T 14-10-2018 IPR036346 GTP-binding protein OBG, C-terminal domain superfamily MB46_08955 f371a3bbcd541c6c37931688d18834e9 537 Pfam PF01926 50S ribosome-binding GTPase 161 269 2.3E-22 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 MB46_08955 f371a3bbcd541c6c37931688d18834e9 537 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 183 201 2.1E-34 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 MB46_08955 f371a3bbcd541c6c37931688d18834e9 537 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 227 245 2.1E-34 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 MB46_08955 f371a3bbcd541c6c37931688d18834e9 537 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 162 182 2.1E-34 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 MB46_08955 f371a3bbcd541c6c37931688d18834e9 537 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 210 225 2.1E-34 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 MB46_08955 f371a3bbcd541c6c37931688d18834e9 537 SUPERFAMILY SSF82051 4 157 6.28E-42 T 14-10-2018 IPR036726 GTP1/OBG domain superfamily MB46_08955 f371a3bbcd541c6c37931688d18834e9 537 Gene3D G3DSA:2.70.210.12 3 158 4.5E-44 T 14-10-2018 IPR036726 GTP1/OBG domain superfamily MB46_08955 f371a3bbcd541c6c37931688d18834e9 537 Pfam PF09269 Domain of unknown function (DUF1967) 371 445 1.0E-22 T 14-10-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 MB46_08955 f371a3bbcd541c6c37931688d18834e9 537 Hamap MF_01454 GTPase Obg [obg]. 3 343 41.337 T 14-10-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 MB46_08955 f371a3bbcd541c6c37931688d18834e9 537 ProSitePatterns PS00905 GTP1/OBG family signature. 212 225 - T 14-10-2018 IPR006074 GTP1/OBG, conserved site GO:0005525 MB46_08955 f371a3bbcd541c6c37931688d18834e9 537 Gene3D G3DSA:3.40.50.300 160 372 4.8E-48 T 14-10-2018 MB46_08955 f371a3bbcd541c6c37931688d18834e9 537 Pfam PF01018 GTP1/OBG 5 157 5.8E-45 T 14-10-2018 IPR006169 GTP1/OBG domain MB46_08955 f371a3bbcd541c6c37931688d18834e9 537 SUPERFAMILY SSF52540 161 343 1.17E-46 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_16180 4b1e563241d55881166224ad38420d05 885 Pfam PF13604 AAA domain 10 133 2.1E-8 T 14-10-2018 MB46_16180 4b1e563241d55881166224ad38420d05 885 SUPERFAMILY SSF52540 18 201 7.57E-10 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_16180 4b1e563241d55881166224ad38420d05 885 Gene3D G3DSA:3.40.50.300 3 148 4.2E-6 T 14-10-2018 MB46_16180 4b1e563241d55881166224ad38420d05 885 Pfam PF00196 Bacterial regulatory proteins, luxR family 817 867 3.3E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_16180 4b1e563241d55881166224ad38420d05 885 ProSitePatterns PS00622 LuxR-type HTH domain signature. 831 858 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_16180 4b1e563241d55881166224ad38420d05 885 SUPERFAMILY SSF46894 810 868 2.48E-13 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MB46_16180 4b1e563241d55881166224ad38420d05 885 Gene3D G3DSA:1.10.10.10 817 880 4.4E-15 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_16180 4b1e563241d55881166224ad38420d05 885 SMART SM00421 814 871 3.1E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_16180 4b1e563241d55881166224ad38420d05 885 Gene3D G3DSA:1.25.40.10 454 800 3.0E-5 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MB46_16180 4b1e563241d55881166224ad38420d05 885 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 847 859 2.2E-7 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_16180 4b1e563241d55881166224ad38420d05 885 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 831 847 2.2E-7 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_16180 4b1e563241d55881166224ad38420d05 885 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 817 831 2.2E-7 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_01785 05514b01255080314deb63e78096696c 391 Pfam PF00842 Alanine racemase, C-terminal domain 260 387 1.1E-34 T 14-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MB46_01785 05514b01255080314deb63e78096696c 391 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 44 54 - T 14-10-2018 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MB46_01785 05514b01255080314deb63e78096696c 391 PRINTS PR00992 Alanine racemase signature 39 55 1.4E-53 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MB46_01785 05514b01255080314deb63e78096696c 391 PRINTS PR00992 Alanine racemase signature 139 151 1.4E-53 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MB46_01785 05514b01255080314deb63e78096696c 391 PRINTS PR00992 Alanine racemase signature 176 187 1.4E-53 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MB46_01785 05514b01255080314deb63e78096696c 391 PRINTS PR00992 Alanine racemase signature 219 246 1.4E-53 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MB46_01785 05514b01255080314deb63e78096696c 391 PRINTS PR00992 Alanine racemase signature 293 308 1.4E-53 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MB46_01785 05514b01255080314deb63e78096696c 391 PRINTS PR00992 Alanine racemase signature 75 93 1.4E-53 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MB46_01785 05514b01255080314deb63e78096696c 391 PRINTS PR00992 Alanine racemase signature 314 331 1.4E-53 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MB46_01785 05514b01255080314deb63e78096696c 391 PRINTS PR00992 Alanine racemase signature 276 291 1.4E-53 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MB46_01785 05514b01255080314deb63e78096696c 391 PRINTS PR00992 Alanine racemase signature 370 383 1.4E-53 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MB46_01785 05514b01255080314deb63e78096696c 391 Gene3D G3DSA:2.40.37.10 21 387 2.3E-110 T 14-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 MB46_01785 05514b01255080314deb63e78096696c 391 SMART SM01005 260 388 2.0E-48 T 14-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MB46_01785 05514b01255080314deb63e78096696c 391 TIGRFAM TIGR00492 alr: alanine racemase 18 387 2.5E-89 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MB46_01785 05514b01255080314deb63e78096696c 391 SUPERFAMILY SSF51419 21 261 3.49E-57 T 14-10-2018 IPR029066 PLP-binding barrel MB46_01785 05514b01255080314deb63e78096696c 391 Pfam PF01168 Alanine racemase, N-terminal domain 21 246 1.1E-59 T 14-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MB46_01785 05514b01255080314deb63e78096696c 391 SUPERFAMILY SSF50621 253 389 7.67E-39 T 14-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 MB46_01785 05514b01255080314deb63e78096696c 391 Gene3D G3DSA:3.20.20.10 23 241 2.3E-110 T 14-10-2018 IPR029066 PLP-binding barrel MB46_01785 05514b01255080314deb63e78096696c 391 Hamap MF_01201 Alanine racemase. 14 388 29.331 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MB46_16105 ac02a386eb819b9bd25dd1657e444516 374 SUPERFAMILY SSF55979 245 371 2.13E-27 T 14-10-2018 MB46_16105 ac02a386eb819b9bd25dd1657e444516 374 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 1 371 1.0E-89 T 14-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 MB46_16105 ac02a386eb819b9bd25dd1657e444516 374 SUPERFAMILY SSF55979 2 118 1.78E-25 T 14-10-2018 MB46_16105 ac02a386eb819b9bd25dd1657e444516 374 Gene3D G3DSA:3.10.150.10 123 246 2.6E-34 T 14-10-2018 MB46_16105 ac02a386eb819b9bd25dd1657e444516 374 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 2 118 1.4E-35 T 14-10-2018 IPR022634 DNA polymerase III, beta sliding clamp, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 MB46_16105 ac02a386eb819b9bd25dd1657e444516 374 SMART SM00480 17 367 1.1E-107 T 14-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 MB46_16105 ac02a386eb819b9bd25dd1657e444516 374 Gene3D G3DSA:3.10.150.10 248 373 1.9E-38 T 14-10-2018 MB46_16105 ac02a386eb819b9bd25dd1657e444516 374 Gene3D G3DSA:3.10.150.10 1 121 9.0E-44 T 14-10-2018 MB46_16105 ac02a386eb819b9bd25dd1657e444516 374 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 245 369 1.3E-26 T 14-10-2018 IPR022635 DNA polymerase III, beta sliding clamp, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 MB46_16105 ac02a386eb819b9bd25dd1657e444516 374 PIRSF PIRSF000804 1 372 2.6E-97 T 14-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 MB46_16105 ac02a386eb819b9bd25dd1657e444516 374 Pfam PF02767 DNA polymerase III beta subunit, central domain 127 243 6.2E-28 T 14-10-2018 IPR022637 DNA polymerase III, beta sliding clamp, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 MB46_16105 ac02a386eb819b9bd25dd1657e444516 374 SUPERFAMILY SSF55979 126 242 1.95E-23 T 14-10-2018 MB46_15555 f14381df955006fe1e0fb8379b08333c 162 Pfam PF00719 Inorganic pyrophosphatase 5 157 6.6E-52 T 14-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 MB46_15555 f14381df955006fe1e0fb8379b08333c 162 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 1 158 31.428 T 14-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 MB46_15555 f14381df955006fe1e0fb8379b08333c 162 Gene3D G3DSA:3.90.80.10 1 162 9.8E-63 T 14-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 MB46_15555 f14381df955006fe1e0fb8379b08333c 162 ProSitePatterns PS00387 Inorganic pyrophosphatase signature. 52 58 - T 14-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 MB46_15555 f14381df955006fe1e0fb8379b08333c 162 SUPERFAMILY SSF50324 4 157 1.7E-53 T 14-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 MB46_14185 983556e8f7c36a84676f08edcec7bfdc 423 Gene3D G3DSA:3.30.950.10 288 415 2.9E-33 T 14-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 MB46_14185 983556e8f7c36a84676f08edcec7bfdc 423 Gene3D G3DSA:3.40.50.720 6 133 1.4E-26 T 14-10-2018 MB46_14185 983556e8f7c36a84676f08edcec7bfdc 423 Gene3D G3DSA:3.40.1010.10 170 287 1.3E-38 T 14-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 MB46_14185 983556e8f7c36a84676f08edcec7bfdc 423 SUPERFAMILY SSF53790 170 400 4.32E-67 T 14-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 MB46_14185 983556e8f7c36a84676f08edcec7bfdc 423 PIRSF PIRSF036426 4 159 8.3E-28 T 14-10-2018 IPR012409 Sirohaem synthase GO:0004851|GO:0009236|GO:0019354|GO:0043115|GO:0051266|GO:0051287 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 MB46_14185 983556e8f7c36a84676f08edcec7bfdc 423 PIRSF PIRSF036426 155 415 1.0E-82 T 14-10-2018 IPR012409 Sirohaem synthase GO:0004851|GO:0009236|GO:0019354|GO:0043115|GO:0051266|GO:0051287 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 MB46_14185 983556e8f7c36a84676f08edcec7bfdc 423 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 172 400 2.4E-78 T 14-10-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0008168|GO:0019354 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 MB46_14185 983556e8f7c36a84676f08edcec7bfdc 423 TIGRFAM TIGR01470 cysG_Nterm: siroheme synthase, N-terminal domain 8 150 1.2E-21 T 14-10-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 MB46_14185 983556e8f7c36a84676f08edcec7bfdc 423 Pfam PF13241 Putative NAD(P)-binding 12 117 3.1E-17 T 14-10-2018 MB46_14185 983556e8f7c36a84676f08edcec7bfdc 423 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 174 377 1.5E-41 T 14-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 MB46_14185 983556e8f7c36a84676f08edcec7bfdc 423 SUPERFAMILY SSF51735 5 106 1.48E-15 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_05590 2fad5170b33f7dc989f128e688b8da54 398 Gene3D G3DSA:3.60.21.10 56 361 1.5E-12 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like MB46_05590 2fad5170b33f7dc989f128e688b8da54 398 Pfam PF00149 Calcineurin-like phosphoesterase 56 313 7.9E-18 T 14-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 MB46_05590 2fad5170b33f7dc989f128e688b8da54 398 SUPERFAMILY SSF56300 52 358 3.26E-36 T 14-10-2018 MB46_09060 ab68ee95f8ffca5f7b9b151dfb124cff 454 Gene3D G3DSA:3.30.70.1050 1 120 8.3E-27 T 14-10-2018 IPR036611 Trigger factor ribosome-binding domain superfamily GO:0006457|GO:0015031 MB46_09060 ab68ee95f8ffca5f7b9b151dfb124cff 454 SUPERFAMILY SSF109998 248 424 4.97E-36 T 14-10-2018 IPR027304 Trigger factor/SurA domain superfamily MB46_09060 ab68ee95f8ffca5f7b9b151dfb124cff 454 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 260 407 7.7E-24 T 14-10-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 MB46_09060 ab68ee95f8ffca5f7b9b151dfb124cff 454 Pfam PF05697 Bacterial trigger factor protein (TF) 3 149 7.2E-37 T 14-10-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 MB46_09060 ab68ee95f8ffca5f7b9b151dfb124cff 454 TIGRFAM TIGR00115 tig: trigger factor 12 406 8.3E-102 T 14-10-2018 IPR005215 Trigger factor GO:0015031 MB46_09060 ab68ee95f8ffca5f7b9b151dfb124cff 454 Gene3D G3DSA:1.10.3120.10 121 411 2.7E-59 T 14-10-2018 IPR037041 Trigger factor, C-terminal domain superfamily GO:0006457|GO:0015031 MB46_09060 ab68ee95f8ffca5f7b9b151dfb124cff 454 SUPERFAMILY SSF54534 138 246 6.68E-16 T 14-10-2018 MB46_09060 ab68ee95f8ffca5f7b9b151dfb124cff 454 Gene3D G3DSA:3.10.50.40 155 245 2.7E-59 T 14-10-2018 MB46_09060 ab68ee95f8ffca5f7b9b151dfb124cff 454 PIRSF PIRSF003095 1 425 1.5E-98 T 14-10-2018 IPR005215 Trigger factor GO:0015031 MB46_09060 ab68ee95f8ffca5f7b9b151dfb124cff 454 Hamap MF_00303 Trigger factor [tig]. 1 413 16.729 T 14-10-2018 IPR005215 Trigger factor GO:0015031 MB46_09060 ab68ee95f8ffca5f7b9b151dfb124cff 454 SUPERFAMILY SSF102735 3 135 3.27E-31 T 14-10-2018 IPR036611 Trigger factor ribosome-binding domain superfamily GO:0006457|GO:0015031 MB46_07875 df4366c23568c0d34f843c123dc90308 663 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 3 639 39.744 T 14-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 MB46_07875 df4366c23568c0d34f843c123dc90308 663 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 4 287 9.7E-104 T 14-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 MB46_07875 df4366c23568c0d34f843c123dc90308 663 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 6 636 1.2E-178 T 14-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 MB46_07875 df4366c23568c0d34f843c123dc90308 663 Gene3D G3DSA:3.40.50.970 322 493 6.7E-57 T 14-10-2018 MB46_07875 df4366c23568c0d34f843c123dc90308 663 Pfam PF02780 Transketolase, C-terminal domain 517 630 7.9E-23 T 14-10-2018 IPR033248 Transketolase, C-terminal domain MB46_07875 df4366c23568c0d34f843c123dc90308 663 Pfam PF02779 Transketolase, pyrimidine binding domain 325 485 3.5E-38 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain MB46_07875 df4366c23568c0d34f843c123dc90308 663 ProSitePatterns PS00801 Transketolase signature 1. 29 48 - T 14-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 MB46_07875 df4366c23568c0d34f843c123dc90308 663 ProSitePatterns PS00802 Transketolase signature 2. 430 446 - T 14-10-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 MB46_07875 df4366c23568c0d34f843c123dc90308 663 SUPERFAMILY SSF52518 21 371 6.88E-67 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold MB46_07875 df4366c23568c0d34f843c123dc90308 663 SUPERFAMILY SSF52518 319 485 9.97E-53 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold MB46_07875 df4366c23568c0d34f843c123dc90308 663 SUPERFAMILY SSF52922 518 636 1.96E-20 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 MB46_07875 df4366c23568c0d34f843c123dc90308 663 SMART SM00861 324 489 1.7E-53 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain MB46_07875 df4366c23568c0d34f843c123dc90308 663 Gene3D G3DSA:3.40.50.920 515 644 8.3E-25 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 MB46_08705 ec8192ed9364fb2f73308e591404442e 298 Gene3D G3DSA:3.20.20.70 2 297 2.1E-68 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MB46_08705 ec8192ed9364fb2f73308e591404442e 298 SMART SM01130 4 293 1.3E-35 T 14-10-2018 IPR002220 DapA-like GO:0016829 MB46_08705 ec8192ed9364fb2f73308e591404442e 298 Pfam PF00701 Dihydrodipicolinate synthetase family 5 293 1.9E-33 T 14-10-2018 IPR002220 DapA-like GO:0016829 MB46_08705 ec8192ed9364fb2f73308e591404442e 298 PIRSF PIRSF001365 1 297 6.8E-47 T 14-10-2018 IPR002220 DapA-like GO:0016829 MB46_08705 ec8192ed9364fb2f73308e591404442e 298 PRINTS PR00146 Dihydrodipicolinate synthase signature 38 59 5.3E-9 T 14-10-2018 IPR002220 DapA-like GO:0016829 MB46_08705 ec8192ed9364fb2f73308e591404442e 298 PRINTS PR00146 Dihydrodipicolinate synthase signature 138 155 5.3E-9 T 14-10-2018 IPR002220 DapA-like GO:0016829 MB46_08705 ec8192ed9364fb2f73308e591404442e 298 PRINTS PR00146 Dihydrodipicolinate synthase signature 81 99 5.3E-9 T 14-10-2018 IPR002220 DapA-like GO:0016829 MB46_08705 ec8192ed9364fb2f73308e591404442e 298 SUPERFAMILY SSF51569 1 295 1.15E-50 T 14-10-2018 MB46_05125 1c253fcd58236b1f73a4a2f6db035d81 325 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_05125 1c253fcd58236b1f73a4a2f6db035d81 325 SUPERFAMILY SSF52540 6 234 6.38E-53 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_05125 1c253fcd58236b1f73a4a2f6db035d81 325 Gene3D G3DSA:3.40.50.300 3 247 9.0E-54 T 14-10-2018 MB46_05125 1c253fcd58236b1f73a4a2f6db035d81 325 Pfam PF00005 ABC transporter 33 171 4.3E-25 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_05125 1c253fcd58236b1f73a4a2f6db035d81 325 SMART SM00382 41 219 2.2E-7 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_19355 81d06129219b2b778c27e610382a720d 385 ProSitePatterns PS00894 DeoR-type HTH domain signature. 8 42 - T 14-10-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 MB46_19355 81d06129219b2b778c27e610382a720d 385 SUPERFAMILY SSF46785 6 61 6.92E-10 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_19355 81d06129219b2b778c27e610382a720d 385 SMART SM00420 8 60 6.5E-11 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MB46_19355 81d06129219b2b778c27e610382a720d 385 SUPERFAMILY SSF53822 74 326 5.89E-43 T 14-10-2018 IPR028082 Periplasmic binding protein-like I MB46_19355 81d06129219b2b778c27e610382a720d 385 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 26 40 1.3E-7 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MB46_19355 81d06129219b2b778c27e610382a720d 385 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 40 58 1.3E-7 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MB46_19355 81d06129219b2b778c27e610382a720d 385 Gene3D G3DSA:1.10.10.10 5 60 2.2E-6 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_19355 81d06129219b2b778c27e610382a720d 385 Gene3D G3DSA:3.40.50.2300 75 324 1.7E-53 T 14-10-2018 MB46_19355 81d06129219b2b778c27e610382a720d 385 Pfam PF08220 DeoR-like helix-turn-helix domain 8 61 4.1E-13 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MB46_19355 81d06129219b2b778c27e610382a720d 385 Gene3D G3DSA:3.40.50.2300 182 305 1.7E-53 T 14-10-2018 MB46_19355 81d06129219b2b778c27e610382a720d 385 Pfam PF13377 Periplasmic binding protein-like domain 190 357 1.5E-26 T 14-10-2018 MB46_04685 f34767b68ca04ac8bd092d53d663e36c 355 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 306 326 - T 14-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 MB46_04685 f34767b68ca04ac8bd092d53d663e36c 355 Hamap MF_00225 Dihydroorotate dehydrogenase (quinone) [pyrD]. 3 350 45.071 T 14-10-2018 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 MB46_04685 f34767b68ca04ac8bd092d53d663e36c 355 TIGRFAM TIGR01036 pyrD_sub2: dihydroorotate dehydrogenase (fumarate) 9 353 2.1E-120 T 14-10-2018 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 MB46_04685 f34767b68ca04ac8bd092d53d663e36c 355 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 85 104 - T 14-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 MB46_04685 f34767b68ca04ac8bd092d53d663e36c 355 Gene3D G3DSA:3.20.20.70 3 355 4.7E-119 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MB46_04685 f34767b68ca04ac8bd092d53d663e36c 355 Pfam PF01180 Dihydroorotate dehydrogenase 50 352 8.0E-92 T 14-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 MB46_04685 f34767b68ca04ac8bd092d53d663e36c 355 SUPERFAMILY SSF51395 4 352 7.33E-93 T 14-10-2018 MB46_04685 f34767b68ca04ac8bd092d53d663e36c 355 PIRSF PIRSF000164 21 355 2.5E-98 T 14-10-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 MB46_07655 14a0f8f8666e5bc4c9c57c7c93aad7e7 517 PRINTS PR00095 Anthranilate synthase component I signature 354 367 1.3E-22 T 14-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MB46_07655 14a0f8f8666e5bc4c9c57c7c93aad7e7 517 PRINTS PR00095 Anthranilate synthase component I signature 434 448 1.3E-22 T 14-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MB46_07655 14a0f8f8666e5bc4c9c57c7c93aad7e7 517 PRINTS PR00095 Anthranilate synthase component I signature 449 463 1.3E-22 T 14-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MB46_07655 14a0f8f8666e5bc4c9c57c7c93aad7e7 517 PRINTS PR00095 Anthranilate synthase component I signature 340 353 1.3E-22 T 14-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MB46_07655 14a0f8f8666e5bc4c9c57c7c93aad7e7 517 TIGRFAM TIGR00564 trpE_most: anthranilate synthase component I 32 500 1.9E-167 T 14-10-2018 IPR005256 Anthranilate synthase component I, PabB-like GO:0000162|GO:0004049 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MB46_07655 14a0f8f8666e5bc4c9c57c7c93aad7e7 517 Pfam PF00425 chorismate binding enzyme 234 492 2.0E-91 T 14-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal MB46_07655 14a0f8f8666e5bc4c9c57c7c93aad7e7 517 Pfam PF04715 Anthranilate synthase component I, N terminal region 33 174 1.9E-25 T 14-10-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MB46_07655 14a0f8f8666e5bc4c9c57c7c93aad7e7 517 Gene3D G3DSA:3.60.120.10 3 509 1.5E-177 T 14-10-2018 IPR005801 ADC synthase GO:0009058 MB46_07655 14a0f8f8666e5bc4c9c57c7c93aad7e7 517 SUPERFAMILY SSF56322 22 500 8.63E-140 T 14-10-2018 IPR005801 ADC synthase GO:0009058 MB46_19110 161f095f6c266e49310895885ffa20fc 1231 SUPERFAMILY SSF51445 740 1122 6.26E-111 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily MB46_19110 161f095f6c266e49310895885ffa20fc 1231 SUPERFAMILY SSF51011 1126 1228 3.96E-31 T 14-10-2018 MB46_19110 161f095f6c266e49310895885ffa20fc 1231 SUPERFAMILY SSF81296 520 618 2.4E-16 T 14-10-2018 IPR014756 Immunoglobulin E-set MB46_19110 161f095f6c266e49310895885ffa20fc 1231 SUPERFAMILY SSF81296 621 729 2.27E-26 T 14-10-2018 IPR014756 Immunoglobulin E-set MB46_19110 161f095f6c266e49310895885ffa20fc 1231 SMART SM00642 758 1120 6.2E-8 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MB46_19110 161f095f6c266e49310895885ffa20fc 1231 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 629 715 4.0E-17 T 14-10-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 MB46_19110 161f095f6c266e49310895885ffa20fc 1231 TIGRFAM TIGR01515 branching_enzym: 1,4-alpha-glucan branching enzyme 613 1226 8.2E-275 T 14-10-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 MB46_19110 161f095f6c266e49310895885ffa20fc 1231 SUPERFAMILY SSF56112 175 451 1.33E-16 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily MB46_19110 161f095f6c266e49310895885ffa20fc 1231 Hamap MF_00685 1,4-alpha-glucan branching enzyme GlgB [glgB]. 605 1229 43.11 T 14-10-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 MB46_19110 161f095f6c266e49310895885ffa20fc 1231 Gene3D G3DSA:3.90.1200.10 257 502 5.9E-67 T 14-10-2018 MB46_19110 161f095f6c266e49310895885ffa20fc 1231 Gene3D G3DSA:2.60.40.1180 1126 1229 1.0E-35 T 14-10-2018 IPR013780 Glycosyl hydrolase, all-beta MB46_19110 161f095f6c266e49310895885ffa20fc 1231 Gene3D G3DSA:3.20.20.80 731 1125 1.6E-174 T 14-10-2018 MB46_19110 161f095f6c266e49310895885ffa20fc 1231 Pfam PF00128 Alpha amylase, catalytic domain 776 849 5.6E-10 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MB46_19110 161f095f6c266e49310895885ffa20fc 1231 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 1131 1227 1.3E-19 T 14-10-2018 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 MB46_19110 161f095f6c266e49310895885ffa20fc 1231 Gene3D G3DSA:2.60.40.10 507 729 7.0E-68 T 14-10-2018 IPR013783 Immunoglobulin-like fold MB46_11740 bdf6d496c171e7da9908fc08a36e839a 403 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 297 2.0E-54 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MB46_11740 bdf6d496c171e7da9908fc08a36e839a 403 SUPERFAMILY SSF51905 2 308 2.46E-41 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_11740 bdf6d496c171e7da9908fc08a36e839a 403 Gene3D G3DSA:3.30.390.30 318 403 9.0E-17 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 MB46_11740 bdf6d496c171e7da9908fc08a36e839a 403 Gene3D G3DSA:3.50.50.60 2 307 1.0E-97 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_11740 bdf6d496c171e7da9908fc08a36e839a 403 Gene3D G3DSA:3.50.50.60 110 236 1.0E-97 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_11740 bdf6d496c171e7da9908fc08a36e839a 403 SUPERFAMILY SSF55424 313 402 1.11E-21 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 MB46_11740 bdf6d496c171e7da9908fc08a36e839a 403 Pfam PF14759 Reductase C-terminal 318 402 1.3E-11 T 14-10-2018 IPR028202 Reductase, C-terminal MB46_11740 bdf6d496c171e7da9908fc08a36e839a 403 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 97 115 1.6E-24 T 14-10-2018 MB46_11740 bdf6d496c171e7da9908fc08a36e839a 403 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 143 161 1.6E-24 T 14-10-2018 MB46_11740 bdf6d496c171e7da9908fc08a36e839a 403 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 1 14 1.6E-24 T 14-10-2018 MB46_11740 bdf6d496c171e7da9908fc08a36e839a 403 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 254 276 1.6E-24 T 14-10-2018 MB46_11740 bdf6d496c171e7da9908fc08a36e839a 403 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 229 245 1.6E-24 T 14-10-2018 MB46_11740 bdf6d496c171e7da9908fc08a36e839a 403 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 230 244 6.6E-7 T 14-10-2018 MB46_11740 bdf6d496c171e7da9908fc08a36e839a 403 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 269 276 6.6E-7 T 14-10-2018 MB46_11740 bdf6d496c171e7da9908fc08a36e839a 403 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 134 159 6.6E-7 T 14-10-2018 MB46_11740 bdf6d496c171e7da9908fc08a36e839a 403 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 100 109 6.6E-7 T 14-10-2018 MB46_01710 c43df6c0b7696966e7ed56350eb4878f 412 Pfam PF13458 Periplasmic binding protein 74 403 1.2E-36 T 14-10-2018 IPR028081 Leucine-binding protein domain MB46_01710 c43df6c0b7696966e7ed56350eb4878f 412 Gene3D G3DSA:3.40.50.2300 76 385 3.8E-72 T 14-10-2018 MB46_01710 c43df6c0b7696966e7ed56350eb4878f 412 Gene3D G3DSA:3.40.50.2300 190 315 3.8E-72 T 14-10-2018 MB46_01710 c43df6c0b7696966e7ed56350eb4878f 412 SUPERFAMILY SSF53822 75 408 8.41E-66 T 14-10-2018 IPR028082 Periplasmic binding protein-like I MB46_00985 040c7b02b4c956a37c1ff868c74db325 231 Gene3D G3DSA:1.10.10.10 1 139 1.9E-49 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_00985 040c7b02b4c956a37c1ff868c74db325 231 SMART SM00899 155 230 1.4E-5 T 14-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 MB46_00985 040c7b02b4c956a37c1ff868c74db325 231 Pfam PF04023 FeoA domain 159 229 1.1E-8 T 14-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 MB46_00985 040c7b02b4c956a37c1ff868c74db325 231 SUPERFAMILY SSF47979 65 136 9.16E-25 T 14-10-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 MB46_00985 040c7b02b4c956a37c1ff868c74db325 231 SUPERFAMILY SSF50037 130 229 1.33E-21 T 14-10-2018 IPR008988 Transcriptional repressor, C-terminal MB46_00985 040c7b02b4c956a37c1ff868c74db325 231 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 65 133 2.9E-27 T 14-10-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 MB46_00985 040c7b02b4c956a37c1ff868c74db325 231 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 3 62 2.3E-18 T 14-10-2018 IPR022687 DTXR-type HTH domain GO:0003677 MB46_00985 040c7b02b4c956a37c1ff868c74db325 231 SUPERFAMILY SSF46785 3 62 1.49E-12 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_00985 040c7b02b4c956a37c1ff868c74db325 231 Gene3D G3DSA:2.30.30.90 150 230 1.8E-7 T 14-10-2018 IPR038157 Ferrous iron transporter, core domain MB46_00985 040c7b02b4c956a37c1ff868c74db325 231 SMART SM00529 26 125 6.9E-39 T 14-10-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 MB46_00440 f8a3f98b8bf92abb8d3e4802b6f088ca 339 Gene3D G3DSA:3.40.50.2300 173 301 1.4E-70 T 14-10-2018 MB46_00440 f8a3f98b8bf92abb8d3e4802b6f088ca 339 Pfam PF00356 Bacterial regulatory proteins, lacI family 14 61 2.3E-16 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MB46_00440 f8a3f98b8bf92abb8d3e4802b6f088ca 339 Gene3D G3DSA:1.10.260.40 7 71 3.0E-21 T 14-10-2018 MB46_00440 f8a3f98b8bf92abb8d3e4802b6f088ca 339 Gene3D G3DSA:3.40.50.2300 73 316 1.4E-70 T 14-10-2018 MB46_00440 f8a3f98b8bf92abb8d3e4802b6f088ca 339 SMART SM00354 12 84 8.9E-21 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MB46_00440 f8a3f98b8bf92abb8d3e4802b6f088ca 339 ProSitePatterns PS00356 LacI-type HTH domain signature. 15 33 - T 14-10-2018 MB46_00440 f8a3f98b8bf92abb8d3e4802b6f088ca 339 Pfam PF13377 Periplasmic binding protein-like domain 181 338 1.3E-31 T 14-10-2018 MB46_00440 f8a3f98b8bf92abb8d3e4802b6f088ca 339 SUPERFAMILY SSF47413 12 72 1.5E-15 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MB46_00440 f8a3f98b8bf92abb8d3e4802b6f088ca 339 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 24 34 5.3E-5 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MB46_00440 f8a3f98b8bf92abb8d3e4802b6f088ca 339 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 14 24 5.3E-5 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MB46_00440 f8a3f98b8bf92abb8d3e4802b6f088ca 339 SUPERFAMILY SSF53822 74 333 2.94E-61 T 14-10-2018 IPR028082 Periplasmic binding protein-like I MB46_05170 22a7872ad6569ea1c0ac4506b5221a3f 405 SUPERFAMILY SSF53901 14 259 1.73E-57 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 MB46_05170 22a7872ad6569ea1c0ac4506b5221a3f 405 Gene3D G3DSA:3.40.47.10 136 397 3.0E-99 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 MB46_05170 22a7872ad6569ea1c0ac4506b5221a3f 405 Pfam PF02803 Thiolase, C-terminal domain 282 398 3.4E-22 T 14-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 MB46_05170 22a7872ad6569ea1c0ac4506b5221a3f 405 PIRSF PIRSF000429 8 404 1.4E-94 T 14-10-2018 IPR002155 Thiolase GO:0016747 MB46_05170 22a7872ad6569ea1c0ac4506b5221a3f 405 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 15 399 4.2E-92 T 14-10-2018 IPR002155 Thiolase GO:0016747 MB46_05170 22a7872ad6569ea1c0ac4506b5221a3f 405 Gene3D G3DSA:3.40.47.10 14 282 3.0E-99 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 MB46_05170 22a7872ad6569ea1c0ac4506b5221a3f 405 ProSitePatterns PS00737 Thiolases signature 2. 347 363 - T 14-10-2018 IPR020613 Thiolase, conserved site GO:0016747 MB46_05170 22a7872ad6569ea1c0ac4506b5221a3f 405 Pfam PF00108 Thiolase, N-terminal domain 14 252 8.8E-54 T 14-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 MB46_05170 22a7872ad6569ea1c0ac4506b5221a3f 405 SUPERFAMILY SSF53901 282 399 2.21E-20 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 MB46_05065 8238e8e337df7a4fce8d0fd6e8491bf2 412 PRINTS PR00477 Phosphoglycerate kinase family signature 34 56 1.5E-74 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MB46_05065 8238e8e337df7a4fce8d0fd6e8491bf2 412 PRINTS PR00477 Phosphoglycerate kinase family signature 113 128 1.5E-74 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MB46_05065 8238e8e337df7a4fce8d0fd6e8491bf2 412 PRINTS PR00477 Phosphoglycerate kinase family signature 364 375 1.5E-74 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MB46_05065 8238e8e337df7a4fce8d0fd6e8491bf2 412 PRINTS PR00477 Phosphoglycerate kinase family signature 178 200 1.5E-74 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MB46_05065 8238e8e337df7a4fce8d0fd6e8491bf2 412 PRINTS PR00477 Phosphoglycerate kinase family signature 13 29 1.5E-74 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MB46_05065 8238e8e337df7a4fce8d0fd6e8491bf2 412 PRINTS PR00477 Phosphoglycerate kinase family signature 388 405 1.5E-74 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MB46_05065 8238e8e337df7a4fce8d0fd6e8491bf2 412 PRINTS PR00477 Phosphoglycerate kinase family signature 148 170 1.5E-74 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MB46_05065 8238e8e337df7a4fce8d0fd6e8491bf2 412 PRINTS PR00477 Phosphoglycerate kinase family signature 328 353 1.5E-74 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MB46_05065 8238e8e337df7a4fce8d0fd6e8491bf2 412 PRINTS PR00477 Phosphoglycerate kinase family signature 201 220 1.5E-74 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MB46_05065 8238e8e337df7a4fce8d0fd6e8491bf2 412 Gene3D G3DSA:3.40.50.1260 14 407 1.5E-125 T 14-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MB46_05065 8238e8e337df7a4fce8d0fd6e8491bf2 412 PIRSF PIRSF000724 1 412 1.1E-118 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MB46_05065 8238e8e337df7a4fce8d0fd6e8491bf2 412 SUPERFAMILY SSF53748 9 411 3.3E-124 T 14-10-2018 IPR036043 Phosphoglycerate kinase superfamily GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MB46_05065 8238e8e337df7a4fce8d0fd6e8491bf2 412 Pfam PF00162 Phosphoglycerate kinase 13 402 6.4E-130 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MB46_05065 8238e8e337df7a4fce8d0fd6e8491bf2 412 Gene3D G3DSA:3.40.50.1260 180 402 1.5E-125 T 14-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MB46_05065 8238e8e337df7a4fce8d0fd6e8491bf2 412 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 5 412 37.644 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MB46_19375 ec157d647332ad0ba93897b551c7c459 306 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 126 294 5.3E-13 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_19375 ec157d647332ad0ba93897b551c7c459 306 SUPERFAMILY SSF161098 33 306 3.27E-54 T 14-10-2018 IPR035906 MetI-like superfamily MB46_19375 ec157d647332ad0ba93897b551c7c459 306 Gene3D G3DSA:1.10.3720.10 27 297 2.4E-54 T 14-10-2018 IPR035906 MetI-like superfamily MB46_06810 144aace9586b324c2671c6d08a68f0d6 425 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 166 181 4.5E-13 T 14-10-2018 MB46_06810 144aace9586b324c2671c6d08a68f0d6 425 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 19 41 4.5E-13 T 14-10-2018 MB46_06810 144aace9586b324c2671c6d08a68f0d6 425 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 297 312 4.5E-13 T 14-10-2018 MB46_06810 144aace9586b324c2671c6d08a68f0d6 425 SUPERFAMILY SSF54373 191 287 2.75E-9 T 14-10-2018 MB46_06810 144aace9586b324c2671c6d08a68f0d6 425 Gene3D G3DSA:3.50.50.60 20 370 1.3E-122 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_06810 144aace9586b324c2671c6d08a68f0d6 425 SUPERFAMILY SSF51905 19 381 5.7E-60 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_06810 144aace9586b324c2671c6d08a68f0d6 425 Gene3D G3DSA:3.30.9.30 52 378 1.3E-122 T 14-10-2018 MB46_06810 144aace9586b324c2671c6d08a68f0d6 425 Pfam PF01494 FAD binding domain 19 328 2.2E-20 T 14-10-2018 IPR002938 FAD-binding domain GO:0071949 MB46_14130 8f115a42215a5f74797da94c6b66fcb3 273 Pfam PF00582 Universal stress protein family 145 265 1.6E-10 T 14-10-2018 IPR006016 UspA MB46_14130 8f115a42215a5f74797da94c6b66fcb3 273 Pfam PF00582 Universal stress protein family 15 119 9.8E-9 T 14-10-2018 IPR006016 UspA MB46_14130 8f115a42215a5f74797da94c6b66fcb3 273 SUPERFAMILY SSF52402 1 124 3.6E-17 T 14-10-2018 MB46_14130 8f115a42215a5f74797da94c6b66fcb3 273 Gene3D G3DSA:3.40.50.620 137 271 9.7E-15 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MB46_14130 8f115a42215a5f74797da94c6b66fcb3 273 SUPERFAMILY SSF52402 144 268 7.62E-16 T 14-10-2018 MB46_14130 8f115a42215a5f74797da94c6b66fcb3 273 Gene3D G3DSA:3.40.50.620 1 119 3.8E-16 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MB46_14130 8f115a42215a5f74797da94c6b66fcb3 273 PRINTS PR01438 Universal stress protein signature 243 265 2.4E-5 T 14-10-2018 IPR006015 Universal stress protein A MB46_14130 8f115a42215a5f74797da94c6b66fcb3 273 PRINTS PR01438 Universal stress protein signature 225 237 2.4E-5 T 14-10-2018 IPR006015 Universal stress protein A MB46_09645 8d9318af6abedbc01927d3fb0dfaa100 451 Gene3D G3DSA:3.90.550.10 46 287 2.5E-20 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MB46_09645 8d9318af6abedbc01927d3fb0dfaa100 451 Pfam PF13641 Glycosyltransferase like family 2 47 297 3.2E-24 T 14-10-2018 MB46_09645 8d9318af6abedbc01927d3fb0dfaa100 451 SUPERFAMILY SSF53448 48 345 5.72E-29 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MB46_08525 3614ae3bd59b6a423aa7e04d61bf6708 367 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 23 356 2.1E-111 T 14-10-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 MB46_08525 3614ae3bd59b6a423aa7e04d61bf6708 367 Gene3D G3DSA:3.40.50.1970 7 180 3.6E-56 T 14-10-2018 MB46_08525 3614ae3bd59b6a423aa7e04d61bf6708 367 Pfam PF01761 3-dehydroquinate synthase 76 331 1.1E-95 T 14-10-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 MB46_08525 3614ae3bd59b6a423aa7e04d61bf6708 367 SUPERFAMILY SSF56796 17 363 2.62E-104 T 14-10-2018 MB46_08525 3614ae3bd59b6a423aa7e04d61bf6708 367 Gene3D G3DSA:1.20.1090.10 181 367 2.0E-67 T 14-10-2018 MB46_08525 3614ae3bd59b6a423aa7e04d61bf6708 367 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 11 367 64.361 T 14-10-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 MB46_08525 3614ae3bd59b6a423aa7e04d61bf6708 367 PIRSF PIRSF001455 15 365 5.4E-100 T 14-10-2018 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 MB46_00550 49192ddd7a93b1cfcdc86de69aa46f42 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 35 2.2E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MB46_00550 49192ddd7a93b1cfcdc86de69aa46f42 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 43 66 2.2E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MB46_00550 49192ddd7a93b1cfcdc86de69aa46f42 201 SUPERFAMILY SSF46689 9 92 1.85E-14 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MB46_00550 49192ddd7a93b1cfcdc86de69aa46f42 201 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 66 1.2E-11 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MB46_00550 49192ddd7a93b1cfcdc86de69aa46f42 201 Gene3D G3DSA:1.10.357.10 10 201 5.7E-28 T 14-10-2018 MB46_12080 0740c92c802b9c2c75bcb7035b191f04 233 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 57 231 3.2E-18 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_12080 0740c92c802b9c2c75bcb7035b191f04 233 Gene3D G3DSA:1.10.3720.10 11 232 4.2E-42 T 14-10-2018 IPR035906 MetI-like superfamily MB46_12080 0740c92c802b9c2c75bcb7035b191f04 233 SUPERFAMILY SSF161098 16 217 1.27E-36 T 14-10-2018 IPR035906 MetI-like superfamily MB46_05460 d2cdfb9a68520d713eb5943132b31e36 547 Gene3D G3DSA:3.20.20.140 59 472 3.2E-82 T 14-10-2018 MB46_05460 d2cdfb9a68520d713eb5943132b31e36 547 SUPERFAMILY SSF51556 58 466 2.8E-29 T 14-10-2018 IPR032466 Metal-dependent hydrolase MB46_05460 d2cdfb9a68520d713eb5943132b31e36 547 Gene3D G3DSA:2.30.40.10 8 486 3.2E-82 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 MB46_05460 d2cdfb9a68520d713eb5943132b31e36 547 Pfam PF07969 Amidohydrolase family 47 533 2.9E-67 T 14-10-2018 IPR013108 Amidohydrolase 3 MB46_05460 d2cdfb9a68520d713eb5943132b31e36 547 SUPERFAMILY SSF51338 5 496 2.06E-11 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 MB46_05460 d2cdfb9a68520d713eb5943132b31e36 547 Gene3D G3DSA:3.10.310.70 77 184 3.2E-82 T 14-10-2018 MB46_14520 5f3ccd40f72055861889aa9c9d90f1a9 946 Gene3D G3DSA:3.40.50.1700 342 667 4.3E-178 T 14-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 MB46_14520 5f3ccd40f72055861889aa9c9d90f1a9 946 SMART SM01217 734 804 1.1E-14 T 14-10-2018 IPR026891 Fibronectin type III-like domain MB46_14520 5f3ccd40f72055861889aa9c9d90f1a9 946 Pfam PF14310 Fibronectin type III-like domain 734 803 1.1E-12 T 14-10-2018 IPR026891 Fibronectin type III-like domain MB46_14520 5f3ccd40f72055861889aa9c9d90f1a9 946 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 45 313 3.4E-39 T 14-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 MB46_14520 5f3ccd40f72055861889aa9c9d90f1a9 946 PRINTS PR00133 Glycosyl hydrolase family 3 signature 71 90 6.4E-8 T 14-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 MB46_14520 5f3ccd40f72055861889aa9c9d90f1a9 946 PRINTS PR00133 Glycosyl hydrolase family 3 signature 159 175 6.4E-8 T 14-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 MB46_14520 5f3ccd40f72055861889aa9c9d90f1a9 946 Gene3D G3DSA:2.60.120.380 436 560 4.3E-178 T 14-10-2018 MB46_14520 5f3ccd40f72055861889aa9c9d90f1a9 946 Gene3D G3DSA:2.60.40.10 705 815 2.3E-20 T 14-10-2018 IPR013783 Immunoglobulin-like fold MB46_14520 5f3ccd40f72055861889aa9c9d90f1a9 946 SUPERFAMILY SSF50405 422 550 1.53E-10 T 14-10-2018 IPR008999 Actin-crosslinking MB46_14520 5f3ccd40f72055861889aa9c9d90f1a9 946 SUPERFAMILY SSF52279 350 700 1.7E-33 T 14-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 MB46_14520 5f3ccd40f72055861889aa9c9d90f1a9 946 SUPERFAMILY SSF51445 22 348 1.79E-67 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily MB46_14520 5f3ccd40f72055861889aa9c9d90f1a9 946 Gene3D G3DSA:3.20.20.300 23 701 4.3E-178 T 14-10-2018 IPR036962 Glycoside hydrolase, family 3, N-terminal domain superfamily GO:0004553|GO:0005975 MB46_14520 5f3ccd40f72055861889aa9c9d90f1a9 946 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 350 700 6.8E-44 T 14-10-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 MB46_06550 8cb89d0714532be0186631a9e21e293b 533 SUPERFAMILY SSF53850 22 529 4.45E-83 T 14-10-2018 MB46_06550 8cb89d0714532be0186631a9e21e293b 533 Pfam PF01547 Bacterial extracellular solute-binding protein 68 378 6.9E-13 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein MB46_06550 8cb89d0714532be0186631a9e21e293b 533 Gene3D G3DSA:3.40.190.10 75 433 3.8E-127 T 14-10-2018 MB46_06550 8cb89d0714532be0186631a9e21e293b 533 Gene3D G3DSA:3.40.190.10 176 527 3.8E-127 T 14-10-2018 MB46_00630 3d123152f8aa189d7834753b1c514023 213 SMART SM00382 32 210 5.0E-6 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_00630 3d123152f8aa189d7834753b1c514023 213 Gene3D G3DSA:3.40.50.300 3 213 4.5E-47 T 14-10-2018 MB46_00630 3d123152f8aa189d7834753b1c514023 213 Pfam PF00005 ABC transporter 23 162 1.2E-23 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_00630 3d123152f8aa189d7834753b1c514023 213 SUPERFAMILY SSF52540 7 211 1.66E-45 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_00630 3d123152f8aa189d7834753b1c514023 213 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_12690 a72c0ce9d22f0400d8abd1c318483d15 330 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 66 322 1.1E-28 T 14-10-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0022857|GO:0043190|GO:0055085 MB46_12690 a72c0ce9d22f0400d8abd1c318483d15 330 SUPERFAMILY SSF53850 64 326 3.75E-30 T 14-10-2018 MB46_12690 a72c0ce9d22f0400d8abd1c318483d15 330 Gene3D G3DSA:3.40.190.120 156 265 1.6E-51 T 14-10-2018 MB46_12690 a72c0ce9d22f0400d8abd1c318483d15 330 Gene3D G3DSA:3.40.190.10 67 326 1.6E-51 T 14-10-2018 MB46_06670 208693b4bf3c9a7d70a694563ab4867f 793 Gene3D G3DSA:3.30.470.20 196 359 1.1E-54 T 14-10-2018 MB46_06670 208693b4bf3c9a7d70a694563ab4867f 793 Gene3D G3DSA:3.50.30.10 362 479 1.5E-39 T 14-10-2018 MB46_06670 208693b4bf3c9a7d70a694563ab4867f 793 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 416 427 - T 14-10-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 MB46_06670 208693b4bf3c9a7d70a694563ab4867f 793 SUPERFAMILY SSF51621 465 789 2.07E-96 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 MB46_06670 208693b4bf3c9a7d70a694563ab4867f 793 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 696 714 - T 14-10-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 MB46_06670 208693b4bf3c9a7d70a694563ab4867f 793 PIRSF PIRSF000854 1 792 0.0 T 14-10-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|MetaCyc: PWY-6142 MB46_06670 208693b4bf3c9a7d70a694563ab4867f 793 Gene3D G3DSA:3.30.1490.20 2 195 2.0E-71 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 MB46_06670 208693b4bf3c9a7d70a694563ab4867f 793 Gene3D G3DSA:3.20.20.60 480 791 2.1E-98 T 14-10-2018 MB46_06670 208693b4bf3c9a7d70a694563ab4867f 793 SUPERFAMILY SSF56059 2 384 2.59E-104 T 14-10-2018 MB46_06670 208693b4bf3c9a7d70a694563ab4867f 793 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 18 344 8.5E-114 T 14-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 MB46_06670 208693b4bf3c9a7d70a694563ab4867f 793 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 483 787 6.6E-60 T 14-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 MB46_06670 208693b4bf3c9a7d70a694563ab4867f 793 TIGRFAM TIGR01418 PEP_synth: phosphoenolpyruvate synthase 5 789 0.0 T 14-10-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|MetaCyc: PWY-6142 MB46_06670 208693b4bf3c9a7d70a694563ab4867f 793 SUPERFAMILY SSF52009 349 466 8.11E-34 T 14-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 MB46_06670 208693b4bf3c9a7d70a694563ab4867f 793 Pfam PF00391 PEP-utilising enzyme, mobile domain 386 457 2.1E-25 T 14-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 MB46_14380 06b9d6407489f58bfba32b778fa29c94 262 Gene3D G3DSA:3.20.20.60 3 261 5.9E-65 T 14-10-2018 MB46_14380 06b9d6407489f58bfba32b778fa29c94 262 SUPERFAMILY SSF51621 7 254 1.48E-60 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 MB46_14380 06b9d6407489f58bfba32b778fa29c94 262 Pfam PF13714 Phosphoenolpyruvate phosphomutase 17 248 4.4E-66 T 14-10-2018 MB46_13950 bbff7f94383b28efc40f9083ddf81ffd 399 PRINTS PR00758 Arsenical pump membrane protein signature 367 391 4.7E-11 T 14-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 MB46_13950 bbff7f94383b28efc40f9083ddf81ffd 399 PRINTS PR00758 Arsenical pump membrane protein signature 95 119 4.7E-11 T 14-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 MB46_13950 bbff7f94383b28efc40f9083ddf81ffd 399 PRINTS PR00758 Arsenical pump membrane protein signature 334 359 4.7E-11 T 14-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 MB46_13950 bbff7f94383b28efc40f9083ddf81ffd 399 Pfam PF02040 Arsenical pump membrane protein 26 392 9.4E-21 T 14-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 MB46_18550 10aa376517e4dfef3721a8aa6c586bd6 502 Gene3D G3DSA:3.30.565.10 352 501 2.2E-38 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MB46_18550 10aa376517e4dfef3721a8aa6c586bd6 502 PRINTS PR00344 Bacterial sensor protein C-terminal signature 426 440 4.8E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MB46_18550 10aa376517e4dfef3721a8aa6c586bd6 502 PRINTS PR00344 Bacterial sensor protein C-terminal signature 444 454 4.8E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MB46_18550 10aa376517e4dfef3721a8aa6c586bd6 502 PRINTS PR00344 Bacterial sensor protein C-terminal signature 484 497 4.8E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MB46_18550 10aa376517e4dfef3721a8aa6c586bd6 502 PRINTS PR00344 Bacterial sensor protein C-terminal signature 461 479 4.8E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MB46_18550 10aa376517e4dfef3721a8aa6c586bd6 502 SUPERFAMILY SSF55874 352 498 7.47E-37 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MB46_18550 10aa376517e4dfef3721a8aa6c586bd6 502 Pfam PF00672 HAMP domain 192 250 1.2E-7 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MB46_18550 10aa376517e4dfef3721a8aa6c586bd6 502 SMART SM00387 388 500 6.5E-36 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MB46_18550 10aa376517e4dfef3721a8aa6c586bd6 502 Pfam PF00512 His Kinase A (phospho-acceptor) domain 263 327 2.5E-20 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MB46_18550 10aa376517e4dfef3721a8aa6c586bd6 502 SMART SM00304 192 254 2.3E-5 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MB46_18550 10aa376517e4dfef3721a8aa6c586bd6 502 SMART SM00388 262 328 2.5E-23 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MB46_18550 10aa376517e4dfef3721a8aa6c586bd6 502 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 389 499 5.8E-22 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MB46_18550 10aa376517e4dfef3721a8aa6c586bd6 502 SUPERFAMILY SSF47384 248 327 5.1E-20 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MB46_18550 10aa376517e4dfef3721a8aa6c586bd6 502 Gene3D G3DSA:1.10.287.130 196 330 1.9E-25 T 14-10-2018 MB46_16405 23e80fab06f1dad63e93ebc5e21ecb3b 370 SUPERFAMILY SSF110296 14 367 6.8E-56 T 14-10-2018 MB46_16405 23e80fab06f1dad63e93ebc5e21ecb3b 370 Gene3D G3DSA:2.130.10.10 2 368 2.9E-104 T 14-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 MB46_08730 0703009aff17443aba17c965ee239925 1180 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 12 1107 9.6E-146 T 14-10-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MB46_08730 0703009aff17443aba17c965ee239925 1180 Pfam PF02811 PHP domain 14 133 1.4E-11 T 14-10-2018 IPR004013 PHP domain GO:0003824 MB46_08730 0703009aff17443aba17c965ee239925 1180 Pfam PF14579 Helix-hairpin-helix motif 867 965 1.0E-15 T 14-10-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MB46_08730 0703009aff17443aba17c965ee239925 1180 SMART SM00481 13 79 5.9E-6 T 14-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal MB46_08730 0703009aff17443aba17c965ee239925 1180 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 328 782 3.9E-112 T 14-10-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MB46_08730 0703009aff17443aba17c965ee239925 1180 Gene3D G3DSA:3.20.20.140 2 300 1.1E-48 T 14-10-2018 MB46_08730 0703009aff17443aba17c965ee239925 1180 Gene3D G3DSA:1.10.10.1600 464 560 2.8E-5 T 14-10-2018 MB46_04205 c48fc7ea3c2fa48e9e74eb20bbb81a7f 746 Gene3D G3DSA:3.40.50.300 170 272 1.8E-9 T 14-10-2018 MB46_04205 c48fc7ea3c2fa48e9e74eb20bbb81a7f 746 Gene3D G3DSA:3.40.50.300 588 746 2.4E-13 T 14-10-2018 MB46_04205 c48fc7ea3c2fa48e9e74eb20bbb81a7f 746 Pfam PF13086 AAA domain 179 556 5.3E-8 T 14-10-2018 MB46_04205 c48fc7ea3c2fa48e9e74eb20bbb81a7f 746 SUPERFAMILY SSF52540 170 739 3.66E-43 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_04205 c48fc7ea3c2fa48e9e74eb20bbb81a7f 746 Gene3D G3DSA:3.40.50.300 454 587 5.8E-9 T 14-10-2018 MB46_01350 d11afa52db4acb4ba73a9aaa54eb7007 308 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 122 301 4.2E-27 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_01350 d11afa52db4acb4ba73a9aaa54eb7007 308 Gene3D G3DSA:1.10.3720.10 93 300 4.2E-19 T 14-10-2018 IPR035906 MetI-like superfamily MB46_01350 d11afa52db4acb4ba73a9aaa54eb7007 308 SUPERFAMILY SSF161098 101 285 2.49E-21 T 14-10-2018 IPR035906 MetI-like superfamily MB46_04175 1cf254bfb477dcd8429b7165ff137302 244 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 16 148 1.2E-18 T 14-10-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 MB46_04175 1cf254bfb477dcd8429b7165ff137302 244 Gene3D G3DSA:1.20.120.450 1 151 1.5E-30 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes MB46_04175 1cf254bfb477dcd8429b7165ff137302 244 SUPERFAMILY SSF55718 156 237 9.77E-5 T 14-10-2018 IPR036527 SCP2 sterol-binding domain superfamily MB46_04175 1cf254bfb477dcd8429b7165ff137302 244 SUPERFAMILY SSF109854 6 153 4.21E-30 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes MB46_04175 1cf254bfb477dcd8429b7165ff137302 244 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 17 213 3.1E-34 T 14-10-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type MB46_03260 5cae280772ec52e3e84d2b56e21a35fe 390 Gene3D G3DSA:3.40.47.10 226 377 1.2E-49 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 MB46_03260 5cae280772ec52e3e84d2b56e21a35fe 390 Pfam PF02797 Chalcone and stilbene synthases, C-terminal domain 236 372 4.7E-24 T 14-10-2018 IPR012328 Chalcone/stilbene synthase, C-terminal MB46_03260 5cae280772ec52e3e84d2b56e21a35fe 390 Gene3D G3DSA:3.40.47.10 2 221 5.2E-69 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 MB46_03260 5cae280772ec52e3e84d2b56e21a35fe 390 SUPERFAMILY SSF53901 1 219 6.51E-49 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 MB46_03260 5cae280772ec52e3e84d2b56e21a35fe 390 PIRSF PIRSF000451 1 376 6.2E-115 T 14-10-2018 IPR011141 Polyketide synthase, type III GO:0009058|GO:0016747 MB46_03260 5cae280772ec52e3e84d2b56e21a35fe 390 Pfam PF00195 Chalcone and stilbene synthases, N-terminal domain 4 217 5.8E-30 T 14-10-2018 IPR001099 Chalcone/stilbene synthase, N-terminal MB46_03260 5cae280772ec52e3e84d2b56e21a35fe 390 SUPERFAMILY SSF53901 225 372 3.4E-35 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 MB46_08295 a9c4368e643d1642a46d4980c6204982 384 SUPERFAMILY SSF100879 234 333 1.47E-26 T 14-10-2018 IPR036775 DNA polymerase, Y-family, little finger domain superfamily GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 MB46_08295 a9c4368e643d1642a46d4980c6204982 384 Hamap MF_01113 DNA polymerase IV [dinB]. 1 347 32.795 T 14-10-2018 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 MB46_08295 a9c4368e643d1642a46d4980c6204982 384 Pfam PF00817 impB/mucB/samB family 3 148 5.0E-43 T 14-10-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 MB46_08295 a9c4368e643d1642a46d4980c6204982 384 Gene3D G3DSA:3.30.1490.100 235 341 4.4E-29 T 14-10-2018 IPR036775 DNA polymerase, Y-family, little finger domain superfamily GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 MB46_08295 a9c4368e643d1642a46d4980c6204982 384 Pfam PF11799 impB/mucB/samB family C-terminal domain 229 336 3.2E-21 T 14-10-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 MB46_08295 a9c4368e643d1642a46d4980c6204982 384 Gene3D G3DSA:1.10.150.20 162 230 8.8E-18 T 14-10-2018 MB46_08295 a9c4368e643d1642a46d4980c6204982 384 Gene3D G3DSA:2.30.40.20 17 68 3.7E-55 T 14-10-2018 MB46_08295 a9c4368e643d1642a46d4980c6204982 384 Gene3D G3DSA:3.30.70.270 1 159 3.7E-55 T 14-10-2018 MB46_08295 a9c4368e643d1642a46d4980c6204982 384 SUPERFAMILY SSF56672 1 229 5.6E-73 T 14-10-2018 MB46_19975 30e5eb8138696e06b90a712346a08bfe 81 Pfam PF00550 Phosphopantetheine attachment site 14 58 1.8E-5 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain MB46_19975 30e5eb8138696e06b90a712346a08bfe 81 SUPERFAMILY SSF47336 18 75 9.68E-9 T 14-10-2018 IPR036736 ACP-like superfamily MB46_19975 30e5eb8138696e06b90a712346a08bfe 81 Gene3D G3DSA:1.10.1200.10 2 77 4.4E-8 T 14-10-2018 IPR036736 ACP-like superfamily MB46_19175 30e5eb8138696e06b90a712346a08bfe 81 Pfam PF00550 Phosphopantetheine attachment site 14 58 1.8E-5 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain MB46_19175 30e5eb8138696e06b90a712346a08bfe 81 SUPERFAMILY SSF47336 18 75 9.68E-9 T 14-10-2018 IPR036736 ACP-like superfamily MB46_19175 30e5eb8138696e06b90a712346a08bfe 81 Gene3D G3DSA:1.10.1200.10 2 77 4.4E-8 T 14-10-2018 IPR036736 ACP-like superfamily MB46_17000 9f9985983828b9b2119b090780320f8e 416 SUPERFAMILY SSF75005 9 316 3.57E-73 T 14-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily MB46_17000 9f9985983828b9b2119b090780320f8e 416 Pfam PF00251 Glycosyl hydrolases family 32 N-terminal domain 12 317 7.8E-65 T 14-10-2018 IPR013148 Glycosyl hydrolase family 32, N-terminal MB46_17000 9f9985983828b9b2119b090780320f8e 416 ProSitePatterns PS00609 Glycosyl hydrolases family 32 active site. 12 25 - T 14-10-2018 IPR018053 Glycoside hydrolase, family 32, active site GO:0004553|GO:0005975 KEGG: 00052+3.2.1.26|KEGG: 00500+3.2.1.26 MB46_17000 9f9985983828b9b2119b090780320f8e 416 Gene3D G3DSA:2.115.10.20 1 333 5.2E-90 T 14-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily MB46_17000 9f9985983828b9b2119b090780320f8e 416 SMART SM00640 12 388 3.6E-61 T 14-10-2018 IPR001362 Glycoside hydrolase, family 32 GO:0004553|GO:0005975 MB46_16485 10a06d1d4da47f28ad15d3a70b29cead 403 ProSitePatterns PS00216 Sugar transport proteins signature 1. 62 78 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MB46_16485 10a06d1d4da47f28ad15d3a70b29cead 403 Gene3D G3DSA:1.20.1250.20 2 396 2.7E-27 T 14-10-2018 MB46_16485 10a06d1d4da47f28ad15d3a70b29cead 403 SUPERFAMILY SSF103473 12 396 1.96E-28 T 14-10-2018 IPR036259 MFS transporter superfamily MB46_16485 10a06d1d4da47f28ad15d3a70b29cead 403 Pfam PF07690 Major Facilitator Superfamily 14 273 1.5E-18 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MB46_03590 9e4c58e144350999aa96db66a9d8ca62 535 SUPERFAMILY SSF52096 25 270 3.47E-71 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MB46_03590 9e4c58e144350999aa96db66a9d8ca62 535 Gene3D G3DSA:3.90.226.10 12 270 5.1E-93 T 14-10-2018 MB46_03590 9e4c58e144350999aa96db66a9d8ca62 535 SUPERFAMILY SSF52096 237 517 1.66E-86 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MB46_03590 9e4c58e144350999aa96db66a9d8ca62 535 Pfam PF01039 Carboxyl transferase domain 48 524 6.3E-150 T 14-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 MB46_03590 9e4c58e144350999aa96db66a9d8ca62 535 Gene3D G3DSA:3.90.226.10 273 535 4.0E-102 T 14-10-2018 MB46_04515 e4100a6bfd6b26de7ba957f3da4b2b3e 706 Pfam PF01844 HNH endonuclease 561 601 6.6E-5 T 14-10-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 MB46_04515 e4100a6bfd6b26de7ba957f3da4b2b3e 706 Pfam PF02720 Domain of unknown function (DUF222) 78 291 2.3E-9 T 14-10-2018 IPR003870 Domain of unknown function DUF222 MB46_04515 e4100a6bfd6b26de7ba957f3da4b2b3e 706 SMART SM00507 544 597 0.002 T 14-10-2018 IPR003615 HNH nuclease MB46_06060 80e6bdd3658786e28e7642cdc0dd5721 318 Gene3D G3DSA:3.40.50.1980 156 318 2.5E-44 T 14-10-2018 MB46_06060 80e6bdd3658786e28e7642cdc0dd5721 318 SUPERFAMILY SSF53807 47 312 9.42E-61 T 14-10-2018 MB46_06060 80e6bdd3658786e28e7642cdc0dd5721 318 Gene3D G3DSA:3.40.50.1980 44 150 5.7E-31 T 14-10-2018 MB46_06060 80e6bdd3658786e28e7642cdc0dd5721 318 Pfam PF01497 Periplasmic binding protein 65 288 7.2E-28 T 14-10-2018 IPR002491 ABC transporter periplasmic binding domain MB46_02430 2697743b345dc383acc1b634be211a63 592 ProSitePatterns PS00211 ABC transporters family signature. 123 137 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_02430 2697743b345dc383acc1b634be211a63 592 Pfam PF00005 ABC transporter 303 438 9.2E-24 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_02430 2697743b345dc383acc1b634be211a63 592 Pfam PF00005 ABC transporter 20 151 1.3E-22 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_02430 2697743b345dc383acc1b634be211a63 592 SUPERFAMILY SSF52540 7 204 9.16E-46 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_02430 2697743b345dc383acc1b634be211a63 592 SUPERFAMILY SSF52540 275 485 1.58E-44 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_02430 2697743b345dc383acc1b634be211a63 592 ProSitePatterns PS00211 ABC transporters family signature. 410 424 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_02430 2697743b345dc383acc1b634be211a63 592 Gene3D G3DSA:3.40.50.300 2 235 3.1E-55 T 14-10-2018 MB46_02430 2697743b345dc383acc1b634be211a63 592 Gene3D G3DSA:3.40.50.300 263 511 4.8E-57 T 14-10-2018 MB46_02430 2697743b345dc383acc1b634be211a63 592 SMART SM00382 311 482 7.6E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_02430 2697743b345dc383acc1b634be211a63 592 SMART SM00382 29 207 5.2E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_08670 d5058e911a2cc264ab7000eb14474e11 210 Pfam PF01330 RuvA N terminal domain 1 61 2.2E-17 T 14-10-2018 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 MB46_08670 d5058e911a2cc264ab7000eb14474e11 210 Gene3D G3DSA:1.10.8.10 137 202 8.9E-12 T 14-10-2018 MB46_08670 d5058e911a2cc264ab7000eb14474e11 210 SMART SM00278 72 91 3.4 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 MB46_08670 d5058e911a2cc264ab7000eb14474e11 210 SMART SM00278 107 126 7.5 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 MB46_08670 d5058e911a2cc264ab7000eb14474e11 210 Pfam PF14520 Helix-hairpin-helix domain 71 128 3.8E-14 T 14-10-2018 MB46_08670 d5058e911a2cc264ab7000eb14474e11 210 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 1 195 1.5E-38 T 14-10-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 MB46_08670 d5058e911a2cc264ab7000eb14474e11 210 SUPERFAMILY SSF47781 66 133 1.5E-18 T 14-10-2018 IPR010994 RuvA domain 2-like MB46_08670 d5058e911a2cc264ab7000eb14474e11 210 SUPERFAMILY SSF46929 150 201 3.14E-9 T 14-10-2018 IPR036267 RuvA, C-terminal domain superfamily MB46_08670 d5058e911a2cc264ab7000eb14474e11 210 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 200 26.939 T 14-10-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 MB46_08670 d5058e911a2cc264ab7000eb14474e11 210 Pfam PF07499 RuvA, C-terminal domain 150 199 1.3E-6 T 14-10-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 MB46_08670 d5058e911a2cc264ab7000eb14474e11 210 SUPERFAMILY SSF50249 1 62 3.48E-13 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold MB46_08670 d5058e911a2cc264ab7000eb14474e11 210 Gene3D G3DSA:2.40.50.140 1 64 8.1E-23 T 14-10-2018 MB46_08670 d5058e911a2cc264ab7000eb14474e11 210 Gene3D G3DSA:1.10.150.20 65 136 5.4E-22 T 14-10-2018 MB46_03230 6f48efa69fa526759cdfec9ee3160ef4 187 Gene3D G3DSA:3.30.460.10 1 130 6.0E-44 T 14-10-2018 MB46_03230 6f48efa69fa526759cdfec9ee3160ef4 187 Gene3D G3DSA:1.10.287.860 131 186 1.6E-20 T 14-10-2018 MB46_03230 6f48efa69fa526759cdfec9ee3160ef4 187 SMART SM00954 25 148 5.4E-41 T 14-10-2018 IPR007685 RelA/SpoT GO:0015969 MB46_03230 6f48efa69fa526759cdfec9ee3160ef4 187 Pfam PF04607 Region found in RelA / SpoT proteins 25 146 4.2E-34 T 14-10-2018 IPR007685 RelA/SpoT GO:0015969 MB46_03230 6f48efa69fa526759cdfec9ee3160ef4 187 SUPERFAMILY SSF81301 2 178 2.78E-52 T 14-10-2018 MB46_15255 6a344a0f0e8e1da98ae7accb0a90061e 262 Gene3D G3DSA:1.10.10.10 1 54 8.7E-7 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_15255 6a344a0f0e8e1da98ae7accb0a90061e 262 SMART SM00420 6 58 1.5E-16 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MB46_15255 6a344a0f0e8e1da98ae7accb0a90061e 262 SUPERFAMILY SSF100950 77 242 9.07E-32 T 14-10-2018 IPR037171 NagB/RpiA transferase-like MB46_15255 6a344a0f0e8e1da98ae7accb0a90061e 262 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 1.1E-9 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MB46_15255 6a344a0f0e8e1da98ae7accb0a90061e 262 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 1.1E-9 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MB46_15255 6a344a0f0e8e1da98ae7accb0a90061e 262 Pfam PF08220 DeoR-like helix-turn-helix domain 6 57 6.8E-17 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MB46_15255 6a344a0f0e8e1da98ae7accb0a90061e 262 SMART SM01134 74 243 5.4E-61 T 14-10-2018 MB46_15255 6a344a0f0e8e1da98ae7accb0a90061e 262 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 14-10-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 MB46_15255 6a344a0f0e8e1da98ae7accb0a90061e 262 SUPERFAMILY SSF46785 4 58 9.23E-14 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_15255 6a344a0f0e8e1da98ae7accb0a90061e 262 Pfam PF00455 DeoR C terminal sensor domain 77 240 6.2E-45 T 14-10-2018 IPR014036 DeoR C-terminal sensor domain MB46_13480 e92545e27ae476a2981e31b7f281a8fa 1172 Gene3D G3DSA:3.90.1800.10 1045 1101 7.5E-11 T 14-10-2018 MB46_13480 e92545e27ae476a2981e31b7f281a8fa 1172 Pfam PF04561 RNA polymerase Rpb2, domain 2 175 377 4.8E-25 T 14-10-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MB46_13480 e92545e27ae476a2981e31b7f281a8fa 1172 ProSitePatterns PS01166 RNA polymerases beta chain signature. 882 894 - T 14-10-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MB46_13480 e92545e27ae476a2981e31b7f281a8fa 1172 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 242 857 6.3E-303 T 14-10-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MB46_13480 e92545e27ae476a2981e31b7f281a8fa 1172 Gene3D G3DSA:2.40.50.100 644 718 0.0 T 14-10-2018 MB46_13480 e92545e27ae476a2981e31b7f281a8fa 1172 SUPERFAMILY SSF64484 27 1145 0.0 T 14-10-2018 MB46_13480 e92545e27ae476a2981e31b7f281a8fa 1172 Gene3D G3DSA:3.90.1110.10 180 371 0.0 T 14-10-2018 IPR037034 RNA polymerase Rpb2, domain 2 superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MB46_13480 e92545e27ae476a2981e31b7f281a8fa 1172 Pfam PF10385 RNA polymerase beta subunit external 1 domain 514 582 2.4E-24 T 14-10-2018 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MB46_13480 e92545e27ae476a2981e31b7f281a8fa 1172 Gene3D G3DSA:2.40.270.10 31 1036 0.0 T 14-10-2018 IPR037033 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MB46_13480 e92545e27ae476a2981e31b7f281a8fa 1172 Gene3D G3DSA:3.90.1100.10 33 643 0.0 T 14-10-2018 MB46_13480 e92545e27ae476a2981e31b7f281a8fa 1172 Gene3D G3DSA:2.30.150.10 517 586 0.0 T 14-10-2018 MB46_13480 e92545e27ae476a2981e31b7f281a8fa 1172 Pfam PF04565 RNA polymerase Rpb2, domain 3 436 504 5.8E-28 T 14-10-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MB46_13480 e92545e27ae476a2981e31b7f281a8fa 1172 Pfam PF04560 RNA polymerase Rpb2, domain 7 1060 1134 1.6E-27 T 14-10-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MB46_13480 e92545e27ae476a2981e31b7f281a8fa 1172 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 28 1136 12.25 T 14-10-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MB46_13480 e92545e27ae476a2981e31b7f281a8fa 1172 Gene3D G3DSA:2.40.50.150 754 880 0.0 T 14-10-2018 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MB46_13480 e92545e27ae476a2981e31b7f281a8fa 1172 Pfam PF00562 RNA polymerase Rpb2, domain 6 643 1058 2.8E-154 T 14-10-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MB46_13480 e92545e27ae476a2981e31b7f281a8fa 1172 Pfam PF04563 RNA polymerase beta subunit 85 421 1.4E-22 T 14-10-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MB46_01265 8f32d61bfebe7bfa5e0173eaa55ce6ab 496 ProSitePatterns PS00218 Amino acid permeases signature. 54 84 - T 14-10-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 MB46_01265 8f32d61bfebe7bfa5e0173eaa55ce6ab 496 PIRSF PIRSF006060 7 481 5.7E-66 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 MB46_01265 8f32d61bfebe7bfa5e0173eaa55ce6ab 496 Gene3D G3DSA:1.20.1740.10 22 481 3.5E-58 T 14-10-2018 MB46_01265 8f32d61bfebe7bfa5e0173eaa55ce6ab 496 Pfam PF00324 Amino acid permease 30 453 4.3E-107 T 14-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 MB46_04745 77c4d7d4d382185eaa4cf8edd9f679c9 262 SUPERFAMILY SSF46626 10 129 7.03E-20 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MB46_04745 77c4d7d4d382185eaa4cf8edd9f679c9 262 Gene3D G3DSA:1.10.760.10 142 223 1.4E-9 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MB46_04745 77c4d7d4d382185eaa4cf8edd9f679c9 262 PIRSF PIRSF000007 1 261 9.2E-101 T 14-10-2018 IPR009152 Cytochrome bc1 complex, cytochrome c subunit GO:0005506|GO:0009055|GO:0016021|GO:0020037 KEGG: 00190+1.10.2.2|MetaCyc: PWY-3781|MetaCyc: PWY-6692|MetaCyc: PWY-7082|MetaCyc: PWY-7279 MB46_04745 77c4d7d4d382185eaa4cf8edd9f679c9 262 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 143 216 3.9E-9 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MB46_04745 77c4d7d4d382185eaa4cf8edd9f679c9 262 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 49 122 1.8E-7 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MB46_04745 77c4d7d4d382185eaa4cf8edd9f679c9 262 Gene3D G3DSA:1.10.760.10 3 129 1.3E-13 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MB46_04745 77c4d7d4d382185eaa4cf8edd9f679c9 262 SUPERFAMILY SSF46626 140 218 3.51E-24 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MB46_09705 9cabfe4d2aced00b682922f525aa8c02 330 Gene3D G3DSA:3.40.190.10 78 307 4.9E-38 T 14-10-2018 MB46_09705 9cabfe4d2aced00b682922f525aa8c02 330 SMART SM00062 80 311 3.2E-17 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MB46_09705 9cabfe4d2aced00b682922f525aa8c02 330 SUPERFAMILY SSF53850 66 309 4.26E-38 T 14-10-2018 MB46_09705 9cabfe4d2aced00b682922f525aa8c02 330 Gene3D G3DSA:3.40.190.10 163 273 4.9E-38 T 14-10-2018 MB46_09705 9cabfe4d2aced00b682922f525aa8c02 330 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 81 308 1.4E-33 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MB46_00995 13f74fcd946d2c638be08d26f0f9e3a9 258 Gene3D G3DSA:3.90.1720.10 146 248 6.3E-15 T 14-10-2018 MB46_00995 13f74fcd946d2c638be08d26f0f9e3a9 258 SUPERFAMILY SSF54001 145 246 1.18E-16 T 14-10-2018 IPR038765 Papain-like cysteine peptidase superfamily MB46_00995 13f74fcd946d2c638be08d26f0f9e3a9 258 Pfam PF00877 NlpC/P60 family 166 233 1.7E-11 T 14-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain MB46_12140 c88cf55aa54fbfc1a40bfe3be958c838 191 SUPERFAMILY SSF109854 2 156 1.47E-35 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes MB46_12140 c88cf55aa54fbfc1a40bfe3be958c838 191 Pfam PF04978 Protein of unknown function (DUF664) 7 157 1.5E-44 T 14-10-2018 IPR007061 Protein of unknown function DUF664 MB46_12140 c88cf55aa54fbfc1a40bfe3be958c838 191 Gene3D G3DSA:1.20.120.450 2 158 8.7E-32 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes MB46_05260 f4eb80b87d2364cbddf4a1370e47ae2e 872 TIGRFAM TIGR02412 pepN_strep_liv: aminopeptidase N 6 869 6.4E-285 T 14-10-2018 IPR012778 Peptidase M1, aminopeptidase GO:0004177|GO:0006508 KEGG: 00480+3.4.11.2 MB46_05260 f4eb80b87d2364cbddf4a1370e47ae2e 872 Pfam PF11838 ERAP1-like C-terminal domain 544 861 6.9E-43 T 14-10-2018 IPR024571 ERAP1-like C-terminal domain MB46_05260 f4eb80b87d2364cbddf4a1370e47ae2e 872 Pfam PF01433 Peptidase family M1 domain 245 460 4.3E-59 T 14-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 MB46_05260 f4eb80b87d2364cbddf4a1370e47ae2e 872 SUPERFAMILY SSF55486 225 467 3.87E-71 T 14-10-2018 MB46_05260 f4eb80b87d2364cbddf4a1370e47ae2e 872 Gene3D G3DSA:2.60.40.1730 18 202 4.7E-25 T 14-10-2018 MB46_05260 f4eb80b87d2364cbddf4a1370e47ae2e 872 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 135 150 7.0E-14 T 14-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 MB46_05260 f4eb80b87d2364cbddf4a1370e47ae2e 872 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 277 287 7.0E-14 T 14-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 MB46_05260 f4eb80b87d2364cbddf4a1370e47ae2e 872 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 311 326 7.0E-14 T 14-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 MB46_05260 f4eb80b87d2364cbddf4a1370e47ae2e 872 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 330 342 7.0E-14 T 14-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 MB46_05260 f4eb80b87d2364cbddf4a1370e47ae2e 872 SUPERFAMILY SSF63737 15 201 5.49E-37 T 14-10-2018 MB46_05260 f4eb80b87d2364cbddf4a1370e47ae2e 872 Gene3D G3DSA:1.10.390.60 222 486 2.0E-70 T 14-10-2018 MB46_14980 a8b6d618cf04a768721118f4fcc477fc 216 ProSitePatterns PS00160 KDPG and KHG aldolases Schiff-base forming residue. 127 140 - T 14-10-2018 IPR031338 KDPG/KHG aldolase, active site 2 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 MB46_14980 a8b6d618cf04a768721118f4fcc477fc 216 Gene3D G3DSA:3.20.20.70 1 214 1.8E-59 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MB46_14980 a8b6d618cf04a768721118f4fcc477fc 216 Pfam PF01081 KDPG and KHG aldolase 11 185 1.6E-35 T 14-10-2018 IPR000887 KDPG/KHG aldolase GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 MB46_14980 a8b6d618cf04a768721118f4fcc477fc 216 SUPERFAMILY SSF51569 4 208 1.03E-51 T 14-10-2018 MB46_17090 5b6832d1010103c8f0218e32fd67c07b 357 Gene3D G3DSA:3.20.20.80 42 317 9.6E-58 T 14-10-2018 MB46_17090 5b6832d1010103c8f0218e32fd67c07b 357 SUPERFAMILY SSF51445 48 309 7.19E-28 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily MB46_17090 5b6832d1010103c8f0218e32fd67c07b 357 ProSitePatterns PS01095 Chitinases family 18 active site. 159 167 - T 14-10-2018 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 MB46_16170 80b3ce5b7329414af75cce0f79bd6679 183 SMART SM00903 30 180 1.0E-26 T 14-10-2018 IPR002563 Flavin reductase like domain GO:0010181 MB46_16170 80b3ce5b7329414af75cce0f79bd6679 183 SUPERFAMILY SSF50475 22 181 3.04E-29 T 14-10-2018 MB46_16170 80b3ce5b7329414af75cce0f79bd6679 183 Gene3D G3DSA:2.30.110.10 8 183 1.2E-33 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 MB46_16170 80b3ce5b7329414af75cce0f79bd6679 183 Pfam PF01613 Flavin reductase like domain 33 182 8.5E-22 T 14-10-2018 IPR002563 Flavin reductase like domain GO:0010181 MB46_18315 1a0afd50e2c70bcc5e8b0963429ce6c4 312 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 32 93 1.9E-9 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MB46_18315 1a0afd50e2c70bcc5e8b0963429ce6c4 312 Pfam PF13602 Zinc-binding dehydrogenase 193 307 3.0E-16 T 14-10-2018 MB46_18315 1a0afd50e2c70bcc5e8b0963429ce6c4 312 SUPERFAMILY SSF51735 123 284 2.98E-26 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_18315 1a0afd50e2c70bcc5e8b0963429ce6c4 312 SUPERFAMILY SSF50129 2 155 5.02E-38 T 14-10-2018 IPR011032 GroES-like superfamily MB46_18315 1a0afd50e2c70bcc5e8b0963429ce6c4 312 Gene3D G3DSA:3.40.50.720 134 258 3.0E-81 T 14-10-2018 MB46_18315 1a0afd50e2c70bcc5e8b0963429ce6c4 312 Gene3D G3DSA:3.90.180.10 12 306 3.0E-81 T 14-10-2018 MB46_18315 1a0afd50e2c70bcc5e8b0963429ce6c4 312 SMART SM00829 14 307 4.2E-14 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MB46_08355 d715ecc46cb177627139a8c1ca018a7f 1131 SUPERFAMILY SSF89000 829 997 2.63E-39 T 14-10-2018 MB46_08355 d715ecc46cb177627139a8c1ca018a7f 1131 PIRSF PIRSF001594 1 1131 0.0 T 14-10-2018 IPR005930 Pyruvate carboxylase GO:0004736|GO:0005524|GO:0006090|GO:0006094|GO:0009374 KEGG: 00020+6.4.1.1|KEGG: 00620+6.4.1.1|KEGG: 00720+6.4.1.1|MetaCyc: PWY-5750|MetaCyc: PWY-6142|MetaCyc: PWY-6146|Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 MB46_08355 d715ecc46cb177627139a8c1ca018a7f 1131 Pfam PF00682 HMGL-like 528 800 1.3E-26 T 14-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 MB46_08355 d715ecc46cb177627139a8c1ca018a7f 1131 Gene3D G3DSA:2.40.50.100 1055 1131 1.4E-14 T 14-10-2018 MB46_08355 d715ecc46cb177627139a8c1ca018a7f 1131 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 290 297 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MB46_08355 d715ecc46cb177627139a8c1ca018a7f 1131 Gene3D G3DSA:3.10.600.10 463 1046 9.4E-230 T 14-10-2018 MB46_08355 d715ecc46cb177627139a8c1ca018a7f 1131 Pfam PF00364 Biotin-requiring enzyme 1073 1130 1.8E-11 T 14-10-2018 IPR000089 Biotin/lipoyl attachment MB46_08355 d715ecc46cb177627139a8c1ca018a7f 1131 SUPERFAMILY SSF56059 84 352 1.31E-66 T 14-10-2018 MB46_08355 d715ecc46cb177627139a8c1ca018a7f 1131 Gene3D G3DSA:3.20.20.70 480 995 9.4E-230 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MB46_08355 d715ecc46cb177627139a8c1ca018a7f 1131 SUPERFAMILY SSF51230 1056 1130 3.8E-13 T 14-10-2018 IPR011053 Single hybrid motif MB46_08355 d715ecc46cb177627139a8c1ca018a7f 1131 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 111 8.7E-39 T 14-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MB46_08355 d715ecc46cb177627139a8c1ca018a7f 1131 SUPERFAMILY SSF52440 1 112 1.08E-39 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily MB46_08355 d715ecc46cb177627139a8c1ca018a7f 1131 SMART SM00878 343 450 2.0E-52 T 14-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MB46_08355 d715ecc46cb177627139a8c1ca018a7f 1131 Pfam PF02785 Biotin carboxylase C-terminal domain 343 451 1.9E-34 T 14-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MB46_08355 d715ecc46cb177627139a8c1ca018a7f 1131 SUPERFAMILY SSF51569 523 832 2.38E-76 T 14-10-2018 MB46_08355 d715ecc46cb177627139a8c1ca018a7f 1131 Pfam PF02436 Conserved carboxylase domain 824 1012 3.6E-52 T 14-10-2018 IPR003379 Carboxylase, conserved domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 MB46_08355 d715ecc46cb177627139a8c1ca018a7f 1131 TIGRFAM TIGR01235 pyruv_carbox: pyruvate carboxylase 4 1130 0.0 T 14-10-2018 IPR005930 Pyruvate carboxylase GO:0004736|GO:0005524|GO:0006090|GO:0006094|GO:0009374 KEGG: 00020+6.4.1.1|KEGG: 00620+6.4.1.1|KEGG: 00720+6.4.1.1|MetaCyc: PWY-5750|MetaCyc: PWY-6142|MetaCyc: PWY-6146|Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 MB46_08355 d715ecc46cb177627139a8c1ca018a7f 1131 SUPERFAMILY SSF51246 338 456 1.94E-37 T 14-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 MB46_08355 d715ecc46cb177627139a8c1ca018a7f 1131 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 117 326 2.0E-69 T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MB46_08355 d715ecc46cb177627139a8c1ca018a7f 1131 Gene3D G3DSA:3.30.470.130 1 458 3.4E-183 T 14-10-2018 MB46_17075 e152d6df23ece4c14d161f4da4a18926 188 Gene3D G3DSA:2.30.22.10 130 185 5.1E-19 T 14-10-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 MB46_17075 e152d6df23ece4c14d161f4da4a18926 188 Pfam PF01025 GrpE 52 185 6.3E-33 T 14-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 MB46_17075 e152d6df23ece4c14d161f4da4a18926 188 SUPERFAMILY SSF51064 131 185 3.01E-15 T 14-10-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 MB46_17075 e152d6df23ece4c14d161f4da4a18926 188 Gene3D G3DSA:3.90.20.20 19 128 4.6E-14 T 14-10-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 MB46_17075 e152d6df23ece4c14d161f4da4a18926 188 ProSitePatterns PS01071 grpE protein signature. 141 184 - T 14-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 MB46_17075 e152d6df23ece4c14d161f4da4a18926 188 PRINTS PR00773 GrpE protein signature 165 184 2.0E-20 T 14-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 MB46_17075 e152d6df23ece4c14d161f4da4a18926 188 PRINTS PR00773 GrpE protein signature 90 105 2.0E-20 T 14-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 MB46_17075 e152d6df23ece4c14d161f4da4a18926 188 PRINTS PR00773 GrpE protein signature 138 153 2.0E-20 T 14-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 MB46_17075 e152d6df23ece4c14d161f4da4a18926 188 PRINTS PR00773 GrpE protein signature 62 78 2.0E-20 T 14-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 MB46_17075 e152d6df23ece4c14d161f4da4a18926 188 SUPERFAMILY SSF58014 52 125 4.32E-15 T 14-10-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 MB46_17075 e152d6df23ece4c14d161f4da4a18926 188 Hamap MF_01151 Protein GrpE [grpE]. 2 186 15.702 T 14-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 MB46_02870 0462fdf6f6f2dca36fe951b67efa1e0e 475 PRINTS PR00173 Glutamate-aspartate symporter signature 382 402 3.0E-33 T 14-10-2018 MB46_02870 0462fdf6f6f2dca36fe951b67efa1e0e 475 PRINTS PR00173 Glutamate-aspartate symporter signature 321 347 3.0E-33 T 14-10-2018 MB46_02870 0462fdf6f6f2dca36fe951b67efa1e0e 475 PRINTS PR00173 Glutamate-aspartate symporter signature 219 238 3.0E-33 T 14-10-2018 MB46_02870 0462fdf6f6f2dca36fe951b67efa1e0e 475 PRINTS PR00173 Glutamate-aspartate symporter signature 96 121 3.0E-33 T 14-10-2018 MB46_02870 0462fdf6f6f2dca36fe951b67efa1e0e 475 PRINTS PR00173 Glutamate-aspartate symporter signature 356 375 3.0E-33 T 14-10-2018 MB46_02870 0462fdf6f6f2dca36fe951b67efa1e0e 475 PRINTS PR00173 Glutamate-aspartate symporter signature 18 38 3.0E-33 T 14-10-2018 MB46_02870 0462fdf6f6f2dca36fe951b67efa1e0e 475 PRINTS PR00173 Glutamate-aspartate symporter signature 66 86 3.0E-33 T 14-10-2018 MB46_02870 0462fdf6f6f2dca36fe951b67efa1e0e 475 PRINTS PR00173 Glutamate-aspartate symporter signature 172 194 3.0E-33 T 14-10-2018 MB46_02870 0462fdf6f6f2dca36fe951b67efa1e0e 475 SUPERFAMILY SSF118215 21 428 1.31E-96 T 14-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 MB46_02870 0462fdf6f6f2dca36fe951b67efa1e0e 475 Pfam PF00375 Sodium:dicarboxylate symporter family 22 427 5.0E-110 T 14-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 MB46_02870 0462fdf6f6f2dca36fe951b67efa1e0e 475 Gene3D G3DSA:1.10.3860.10 12 444 4.5E-113 T 14-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 MB46_18805 b919dff235e580792f064a544e2d8804 609 SUPERFAMILY SSF68923 12 246 1.78E-90 T 14-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 MB46_18805 b919dff235e580792f064a544e2d8804 609 Gene3D G3DSA:2.170.8.10 58 402 1.9E-261 T 14-10-2018 MB46_18805 b919dff235e580792f064a544e2d8804 609 PIRSF PIRSF001348 3 609 5.6E-264 T 14-10-2018 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 MB46_18805 b919dff235e580792f064a544e2d8804 609 Hamap MF_00452 Phosphoenolpyruvate carboxykinase [GTP] [pckG]. 11 608 46.793 T 14-10-2018 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 MB46_18805 b919dff235e580792f064a544e2d8804 609 SUPERFAMILY SSF53795 247 607 9.39E-149 T 14-10-2018 MB46_18805 b919dff235e580792f064a544e2d8804 609 Pfam PF00821 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain 247 606 4.0E-162 T 14-10-2018 IPR035077 Phosphoenolpyruvate carboxykinase, GTP-utilising, C-terminal GO:0004611|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 MB46_18805 b919dff235e580792f064a544e2d8804 609 Gene3D G3DSA:3.90.228.20 247 606 1.9E-261 T 14-10-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 MB46_18805 b919dff235e580792f064a544e2d8804 609 Gene3D G3DSA:3.40.449.10 23 246 1.9E-261 T 14-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 MB46_18805 b919dff235e580792f064a544e2d8804 609 Pfam PF17297 Phosphoenolpyruvate carboxykinase N-terminal domain 23 243 2.3E-94 T 14-10-2018 IPR035078 Phosphoenolpyruvate carboxykinase, GTP-utilising, N-terminal GO:0004611|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 MB46_18805 b919dff235e580792f064a544e2d8804 609 ProSitePatterns PS00505 Phosphoenolpyruvate carboxykinase (GTP) signature. 271 279 - T 14-10-2018 IPR018091 Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site GO:0004613 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 MB46_14840 56ad2dcf2339c1596bfb1cbf227f2928 594 Gene3D G3DSA:3.40.50.970 2 171 1.0E-63 T 14-10-2018 MB46_14840 56ad2dcf2339c1596bfb1cbf227f2928 594 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 7 172 3.0E-50 T 14-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 MB46_14840 56ad2dcf2339c1596bfb1cbf227f2928 594 SUPERFAMILY SSF52467 161 336 2.7E-46 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily MB46_14840 56ad2dcf2339c1596bfb1cbf227f2928 594 SUPERFAMILY SSF52518 4 183 8.95E-47 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold MB46_14840 56ad2dcf2339c1596bfb1cbf227f2928 594 Gene3D G3DSA:3.40.50.970 359 582 6.5E-62 T 14-10-2018 MB46_14840 56ad2dcf2339c1596bfb1cbf227f2928 594 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 194 328 5.8E-34 T 14-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 MB46_14840 56ad2dcf2339c1596bfb1cbf227f2928 594 SUPERFAMILY SSF52518 369 565 2.86E-48 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold MB46_14840 56ad2dcf2339c1596bfb1cbf227f2928 594 Gene3D G3DSA:3.40.50.1220 193 357 3.3E-47 T 14-10-2018 MB46_14840 56ad2dcf2339c1596bfb1cbf227f2928 594 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 393 552 6.3E-32 T 14-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 MB46_14840 56ad2dcf2339c1596bfb1cbf227f2928 594 TIGRFAM TIGR01504 glyox_carbo_lig: glyoxylate carboligase 3 589 0.0 T 14-10-2018 IPR006397 Glyoxylate carboligase GO:0009028|GO:0009436 KEGG: 00630+4.1.1.47 MB46_14745 fb99354e0ea480cbed67f184f804881d 113 SMART SM00095 1 112 6.9E-6 T 14-10-2018 IPR023416 Transthyretin/hydroxyisourate hydrolase domain Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 MB46_14745 fb99354e0ea480cbed67f184f804881d 113 Pfam PF00576 HIUase/Transthyretin family 6 112 2.8E-38 T 14-10-2018 IPR023416 Transthyretin/hydroxyisourate hydrolase domain Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 MB46_14745 fb99354e0ea480cbed67f184f804881d 113 SUPERFAMILY SSF49472 2 113 8.24E-41 T 14-10-2018 IPR036817 Transthyretin/hydroxyisourate hydrolase domain superfamily Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 MB46_14745 fb99354e0ea480cbed67f184f804881d 113 Gene3D G3DSA:2.60.40.180 2 113 1.2E-41 T 14-10-2018 IPR036817 Transthyretin/hydroxyisourate hydrolase domain superfamily Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 MB46_14745 fb99354e0ea480cbed67f184f804881d 113 TIGRFAM TIGR02962 hdxy_isourate: hydroxyisourate hydrolase 4 113 1.5E-40 T 14-10-2018 IPR014306 Hydroxyisourate hydrolase GO:0006144|GO:0033971 KEGG: 00230+3.5.2.17|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 MB46_14745 fb99354e0ea480cbed67f184f804881d 113 PRINTS PR00189 Transthyretin signature 91 113 1.4E-9 T 14-10-2018 IPR000895 Transthyretin/hydroxyisourate hydrolase Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 MB46_14745 fb99354e0ea480cbed67f184f804881d 113 PRINTS PR00189 Transthyretin signature 37 62 1.4E-9 T 14-10-2018 IPR000895 Transthyretin/hydroxyisourate hydrolase Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 MB46_14745 fb99354e0ea480cbed67f184f804881d 113 PRINTS PR00189 Transthyretin signature 5 25 1.4E-9 T 14-10-2018 IPR000895 Transthyretin/hydroxyisourate hydrolase Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 MB46_14745 fb99354e0ea480cbed67f184f804881d 113 ProSitePatterns PS00768 Transthyretin signature 1. 9 24 - T 14-10-2018 IPR023418 Transthyretin, thyroxine binding site Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 MB46_03880 9751245d39a7ed5bc317cb49605c1fba 563 Hamap MF_01491 Ribonuclease J [rnj]. 15 563 40.118 T 14-10-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 MB46_03880 9751245d39a7ed5bc317cb49605c1fba 563 SMART SM00849 32 226 4.4E-21 T 14-10-2018 IPR001279 Metallo-beta-lactamase MB46_03880 9751245d39a7ed5bc317cb49605c1fba 563 Gene3D G3DSA:3.40.50.10710 218 375 1.3E-177 T 14-10-2018 MB46_03880 9751245d39a7ed5bc317cb49605c1fba 563 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 21 560 1.4E-153 T 14-10-2018 IPR004613 Ribonuclease J GO:0003723|GO:0046872 MB46_03880 9751245d39a7ed5bc317cb49605c1fba 563 Gene3D G3DSA:3.10.20.580 459 563 9.6E-20 T 14-10-2018 MB46_03880 9751245d39a7ed5bc317cb49605c1fba 563 PIRSF PIRSF004803 13 563 1.1E-212 T 14-10-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 MB46_03880 9751245d39a7ed5bc317cb49605c1fba 563 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 366 408 1.6E-7 T 14-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain MB46_03880 9751245d39a7ed5bc317cb49605c1fba 563 SUPERFAMILY SSF56281 20 434 1.97E-91 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MB46_03880 9751245d39a7ed5bc317cb49605c1fba 563 Gene3D G3DSA:3.60.15.10 21 446 1.3E-177 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MB46_03880 9751245d39a7ed5bc317cb49605c1fba 563 Pfam PF00753 Metallo-beta-lactamase superfamily 30 175 6.9E-13 T 14-10-2018 IPR001279 Metallo-beta-lactamase MB46_00295 1870bf5fa2a8843b83f7c3c9e2aeb342 503 Gene3D G3DSA:3.40.309.10 255 456 3.0E-147 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 MB46_00295 1870bf5fa2a8843b83f7c3c9e2aeb342 503 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 280 291 - T 14-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 MB46_00295 1870bf5fa2a8843b83f7c3c9e2aeb342 503 SUPERFAMILY SSF53720 4 489 1.44E-145 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 MB46_00295 1870bf5fa2a8843b83f7c3c9e2aeb342 503 TIGRFAM TIGR01722 MMSDH: methylmalonate-semialdehyde dehydrogenase (acylating) 10 487 1.2E-216 T 14-10-2018 IPR010061 Methylmalonate-semialdehyde dehydrogenase GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00640+1.2.1.27|MetaCyc: PWY-5642|Reactome: R-HSA-70895 MB46_00295 1870bf5fa2a8843b83f7c3c9e2aeb342 503 Pfam PF00171 Aldehyde dehydrogenase family 25 483 5.3E-135 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 MB46_00295 1870bf5fa2a8843b83f7c3c9e2aeb342 503 Gene3D G3DSA:3.40.605.10 29 464 3.0E-147 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 MB46_10150 974e4e1bb091414289342f50048b1b3e 250 SMART SM00382 42 228 1.6E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_10150 974e4e1bb091414289342f50048b1b3e 250 Gene3D G3DSA:3.40.50.300 12 248 2.7E-66 T 14-10-2018 MB46_10150 974e4e1bb091414289342f50048b1b3e 250 Pfam PF00005 ABC transporter 33 179 1.3E-31 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_10150 974e4e1bb091414289342f50048b1b3e 250 SUPERFAMILY SSF52540 14 232 9.84E-68 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_10150 974e4e1bb091414289342f50048b1b3e 250 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_01825 2e19bc3656913c3b5929ddbe0bdc9d22 565 SUPERFAMILY SSF50891 82 205 1.52E-37 T 14-10-2018 IPR029000 Cyclophilin-like domain superfamily MB46_01825 2e19bc3656913c3b5929ddbe0bdc9d22 565 SMART SM00797 263 550 2.0E-84 T 14-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B MB46_01825 2e19bc3656913c3b5929ddbe0bdc9d22 565 Gene3D G3DSA:2.40.100.10 80 209 4.4E-51 T 14-10-2018 IPR029000 Cyclophilin-like domain superfamily MB46_01825 2e19bc3656913c3b5929ddbe0bdc9d22 565 Gene3D G3DSA:2.40.100.10 419 543 4.3E-39 T 14-10-2018 IPR029000 Cyclophilin-like domain superfamily MB46_01825 2e19bc3656913c3b5929ddbe0bdc9d22 565 Pfam PF02682 Carboxyltransferase domain, subdomain C and D 7 192 1.8E-55 T 14-10-2018 IPR003833 Carboxyltransferase domain, subdomain C and D MB46_01825 2e19bc3656913c3b5929ddbe0bdc9d22 565 Pfam PF02626 Carboxyltransferase domain, subdomain A and B 264 533 3.2E-74 T 14-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B MB46_01825 2e19bc3656913c3b5929ddbe0bdc9d22 565 SUPERFAMILY SSF160467 8 86 3.53E-6 T 14-10-2018 MB46_01825 2e19bc3656913c3b5929ddbe0bdc9d22 565 SMART SM00796 4 193 2.7E-72 T 14-10-2018 IPR003833 Carboxyltransferase domain, subdomain C and D MB46_01825 2e19bc3656913c3b5929ddbe0bdc9d22 565 SUPERFAMILY SSF50891 425 539 2.35E-15 T 14-10-2018 IPR029000 Cyclophilin-like domain superfamily MB46_01825 2e19bc3656913c3b5929ddbe0bdc9d22 565 Gene3D G3DSA:3.30.1360.40 2 78 7.6E-15 T 14-10-2018 MB46_18665 b8a4d9212488e3d21ad0b774e3fa75e2 66 SUPERFAMILY SSF47413 5 58 3.22E-14 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MB46_18665 b8a4d9212488e3d21ad0b774e3fa75e2 66 Gene3D G3DSA:1.10.260.40 5 63 1.6E-17 T 14-10-2018 MB46_18665 b8a4d9212488e3d21ad0b774e3fa75e2 66 SMART SM00530 9 63 3.2E-11 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MB46_18665 b8a4d9212488e3d21ad0b774e3fa75e2 66 Pfam PF13560 Helix-turn-helix domain 6 62 1.8E-13 T 14-10-2018 MB46_00525 113f1a713e0987f3b6ec2f1100166b78 253 Gene3D G3DSA:3.30.450.40 86 250 1.3E-25 T 14-10-2018 IPR029016 GAF-like domain superfamily MB46_00525 113f1a713e0987f3b6ec2f1100166b78 253 SUPERFAMILY SSF46785 9 80 2.16E-7 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_00525 113f1a713e0987f3b6ec2f1100166b78 253 Gene3D G3DSA:1.10.10.10 4 80 2.0E-11 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_00525 113f1a713e0987f3b6ec2f1100166b78 253 Pfam PF09339 IclR helix-turn-helix domain 13 63 3.3E-5 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 MB46_00525 113f1a713e0987f3b6ec2f1100166b78 253 Pfam PF01614 Bacterial transcriptional regulator 133 248 5.7E-13 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal MB46_00525 113f1a713e0987f3b6ec2f1100166b78 253 SUPERFAMILY SSF55781 68 250 2.55E-27 T 14-10-2018 MB46_11690 91b811a025e677e3e861b47a7d8330dd 572 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 254 286 0.0028 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MB46_11690 91b811a025e677e3e861b47a7d8330dd 572 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 526 561 0.018 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MB46_11690 91b811a025e677e3e861b47a7d8330dd 572 SMART SM00382 332 520 4.6E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_11690 91b811a025e677e3e861b47a7d8330dd 572 SMART SM00382 50 252 2.2E-18 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_11690 91b811a025e677e3e861b47a7d8330dd 572 SUPERFAMILY SSF52540 306 546 4.48E-66 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_11690 91b811a025e677e3e861b47a7d8330dd 572 ProSitePatterns PS00211 ABC transporters family signature. 447 461 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_11690 91b811a025e677e3e861b47a7d8330dd 572 SUPERFAMILY SSF52540 21 274 6.09E-67 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_11690 91b811a025e677e3e861b47a7d8330dd 572 Pfam PF00005 ABC transporter 324 475 6.8E-29 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_11690 91b811a025e677e3e861b47a7d8330dd 572 Gene3D G3DSA:3.40.50.300 300 571 1.2E-78 T 14-10-2018 MB46_11690 91b811a025e677e3e861b47a7d8330dd 572 Gene3D G3DSA:3.40.50.300 19 299 1.3E-87 T 14-10-2018 MB46_11690 91b811a025e677e3e861b47a7d8330dd 572 Pfam PF00005 ABC transporter 41 202 3.7E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_11690 91b811a025e677e3e861b47a7d8330dd 572 ProSitePatterns PS00211 ABC transporters family signature. 175 189 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_15005 fef22420b29c56389cb857dbafe4569b 238 SUPERFAMILY SSF46785 4 71 2.49E-13 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_15005 fef22420b29c56389cb857dbafe4569b 238 SUPERFAMILY SSF48008 92 223 4.45E-23 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MB46_15005 fef22420b29c56389cb857dbafe4569b 238 Pfam PF00392 Bacterial regulatory proteins, gntR family 8 67 5.7E-10 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MB46_15005 fef22420b29c56389cb857dbafe4569b 238 SMART SM00895 96 220 2.7E-18 T 14-10-2018 IPR011711 GntR, C-terminal MB46_15005 fef22420b29c56389cb857dbafe4569b 238 Gene3D G3DSA:1.10.10.10 2 68 3.7E-14 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_15005 fef22420b29c56389cb857dbafe4569b 238 Pfam PF07729 FCD domain 98 216 7.9E-21 T 14-10-2018 IPR011711 GntR, C-terminal MB46_15005 fef22420b29c56389cb857dbafe4569b 238 SMART SM00345 9 67 1.1E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MB46_15005 fef22420b29c56389cb857dbafe4569b 238 Gene3D G3DSA:1.20.120.530 91 226 2.8E-24 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MB46_01230 84ad6d86ea22c6d2ea997e1ed6924f69 221 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 7.8E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MB46_01230 84ad6d86ea22c6d2ea997e1ed6924f69 221 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 7.8E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MB46_01230 84ad6d86ea22c6d2ea997e1ed6924f69 221 SUPERFAMILY SSF48498 85 219 4.89E-41 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily MB46_01230 84ad6d86ea22c6d2ea997e1ed6924f69 221 ProSitePatterns PS01081 TetR-type HTH domain signature. 29 60 - T 14-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site MB46_01230 84ad6d86ea22c6d2ea997e1ed6924f69 221 SUPERFAMILY SSF46689 7 87 5.99E-20 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MB46_01230 84ad6d86ea22c6d2ea997e1ed6924f69 221 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 63 6.2E-16 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MB46_01230 84ad6d86ea22c6d2ea997e1ed6924f69 221 Gene3D G3DSA:1.10.357.10 9 219 6.5E-68 T 14-10-2018 MB46_07095 6f31ffbec040e8f34084db437f636596 493 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 261 268 - T 14-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 MB46_07095 6f31ffbec040e8f34084db437f636596 493 Gene3D G3DSA:3.40.605.10 25 480 1.3E-171 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 MB46_07095 6f31ffbec040e8f34084db437f636596 493 Pfam PF00171 Aldehyde dehydrogenase family 25 484 3.8E-166 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 MB46_07095 6f31ffbec040e8f34084db437f636596 493 SUPERFAMILY SSF53720 14 485 2.09E-163 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 MB46_07095 6f31ffbec040e8f34084db437f636596 493 Gene3D G3DSA:3.40.309.10 268 457 1.3E-171 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 MB46_16675 be2acedfa492089c63401b6fc640e693 1035 Pfam PF07748 Glycosyl hydrolases family 38 C-terminal domain 635 1029 1.3E-64 T 14-10-2018 IPR011682 Glycosyl hydrolase family 38, C-terminal GO:0004559|GO:0006013 MB46_16675 be2acedfa492089c63401b6fc640e693 1035 Gene3D G3DSA:3.20.110.10 258 529 1.9E-60 T 14-10-2018 IPR027291 Glycoside hydrolase 38, N-terminal domain superfamily MB46_16675 be2acedfa492089c63401b6fc640e693 1035 SMART SM00872 529 607 7.9E-39 T 14-10-2018 IPR015341 Glycoside hydrolase family 38, central domain GO:0004559|GO:0006013 MB46_16675 be2acedfa492089c63401b6fc640e693 1035 SUPERFAMILY SSF88688 528 627 1.57E-28 T 14-10-2018 IPR028995 Glycoside hydrolase families 57/38, central domain superfamily MB46_16675 be2acedfa492089c63401b6fc640e693 1035 SUPERFAMILY SSF88713 260 527 7.56E-83 T 14-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 MB46_16675 be2acedfa492089c63401b6fc640e693 1035 Pfam PF01074 Glycosyl hydrolases family 38 N-terminal domain 265 520 1.6E-89 T 14-10-2018 IPR000602 Glycoside hydrolase family 38, N-terminal domain GO:0004559|GO:0006013 MB46_16675 be2acedfa492089c63401b6fc640e693 1035 SUPERFAMILY SSF74650 641 1031 2.67E-61 T 14-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 MB46_16675 be2acedfa492089c63401b6fc640e693 1035 Gene3D G3DSA:2.70.98.30 746 923 4.1E-11 T 14-10-2018 MB46_16675 be2acedfa492089c63401b6fc640e693 1035 Gene3D G3DSA:1.20.1270.50 532 627 8.5E-29 T 14-10-2018 IPR037094 Glycoside hydrolase family 38, central domain superfamily GO:0004559|GO:0006013 MB46_16675 be2acedfa492089c63401b6fc640e693 1035 Pfam PF09261 Alpha mannosidase middle domain 529 606 7.0E-28 T 14-10-2018 IPR015341 Glycoside hydrolase family 38, central domain GO:0004559|GO:0006013 MB46_13605 2048883649f07de5f8bce9488c9d7746 374 ProSitePatterns PS00894 DeoR-type HTH domain signature. 18 52 - T 14-10-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 MB46_13605 2048883649f07de5f8bce9488c9d7746 374 Pfam PF08220 DeoR-like helix-turn-helix domain 18 70 1.1E-15 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MB46_13605 2048883649f07de5f8bce9488c9d7746 374 SMART SM00420 18 70 2.4E-15 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MB46_13605 2048883649f07de5f8bce9488c9d7746 374 Pfam PF13377 Periplasmic binding protein-like domain 203 366 1.1E-34 T 14-10-2018 MB46_13605 2048883649f07de5f8bce9488c9d7746 374 Gene3D G3DSA:3.40.50.2300 90 358 2.1E-52 T 14-10-2018 MB46_13605 2048883649f07de5f8bce9488c9d7746 374 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 50 68 8.8E-9 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MB46_13605 2048883649f07de5f8bce9488c9d7746 374 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 36 50 8.8E-9 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MB46_13605 2048883649f07de5f8bce9488c9d7746 374 SUPERFAMILY SSF53822 90 366 9.23E-39 T 14-10-2018 IPR028082 Periplasmic binding protein-like I MB46_13605 2048883649f07de5f8bce9488c9d7746 374 Gene3D G3DSA:3.40.50.2300 195 363 2.1E-52 T 14-10-2018 MB46_13605 2048883649f07de5f8bce9488c9d7746 374 Gene3D G3DSA:1.10.10.10 6 66 2.3E-7 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_13605 2048883649f07de5f8bce9488c9d7746 374 SUPERFAMILY SSF46785 17 72 3.38E-11 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_18850 9d6c2934e580541caf0e8b11162c47bf 444 Gene3D G3DSA:3.20.20.80 16 338 2.4E-117 T 14-10-2018 MB46_18850 9d6c2934e580541caf0e8b11162c47bf 444 PRINTS PR00741 Glycosyl hydrolase family 29 signature 124 143 7.6E-9 T 14-10-2018 IPR016286 Alpha-L-fucosidase, metazoa-type GO:0004560|GO:0006004 KEGG: 00511+3.2.1.51|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 MB46_18850 9d6c2934e580541caf0e8b11162c47bf 444 PRINTS PR00741 Glycosyl hydrolase family 29 signature 79 95 7.6E-9 T 14-10-2018 IPR016286 Alpha-L-fucosidase, metazoa-type GO:0004560|GO:0006004 KEGG: 00511+3.2.1.51|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 MB46_18850 9d6c2934e580541caf0e8b11162c47bf 444 SUPERFAMILY SSF51445 9 338 2.95E-100 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily MB46_18850 9d6c2934e580541caf0e8b11162c47bf 444 PIRSF PIRSF001092 1 395 1.7E-116 T 14-10-2018 IPR016286 Alpha-L-fucosidase, metazoa-type GO:0004560|GO:0006004 KEGG: 00511+3.2.1.51|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 MB46_18850 9d6c2934e580541caf0e8b11162c47bf 444 Pfam PF01120 Alpha-L-fucosidase 13 333 9.9E-92 T 14-10-2018 IPR000933 Glycoside hydrolase, family 29 GO:0004560|GO:0005975 KEGG: 00511+3.2.1.51|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 MB46_18850 9d6c2934e580541caf0e8b11162c47bf 444 Gene3D G3DSA:2.60.40.1180 339 395 2.4E-117 T 14-10-2018 IPR013780 Glycosyl hydrolase, all-beta MB46_18850 9d6c2934e580541caf0e8b11162c47bf 444 SMART SM00812 1 377 1.9E-118 T 14-10-2018 IPR000933 Glycoside hydrolase, family 29 GO:0004560|GO:0005975 KEGG: 00511+3.2.1.51|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 MB46_06005 f2113303b657ddd02201dae14ef439e4 346 Gene3D G3DSA:3.40.50.2300 71 316 1.1E-65 T 14-10-2018 MB46_06005 f2113303b657ddd02201dae14ef439e4 346 SMART SM00354 9 73 6.6E-7 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MB46_06005 f2113303b657ddd02201dae14ef439e4 346 Gene3D G3DSA:1.10.260.40 6 64 9.1E-15 T 14-10-2018 MB46_06005 f2113303b657ddd02201dae14ef439e4 346 Pfam PF00356 Bacterial regulatory proteins, lacI family 15 54 3.1E-13 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MB46_06005 f2113303b657ddd02201dae14ef439e4 346 SUPERFAMILY SSF53822 68 344 3.99E-71 T 14-10-2018 IPR028082 Periplasmic binding protein-like I MB46_06005 f2113303b657ddd02201dae14ef439e4 346 SUPERFAMILY SSF47413 12 58 8.13E-11 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MB46_06005 f2113303b657ddd02201dae14ef439e4 346 Pfam PF13377 Periplasmic binding protein-like domain 179 340 2.6E-41 T 14-10-2018 MB46_06005 f2113303b657ddd02201dae14ef439e4 346 Gene3D G3DSA:3.40.50.2300 171 300 1.1E-65 T 14-10-2018 MB46_11975 2e072420dc630eab5be3431684cdef23 325 Pfam PF09297 NADH pyrophosphatase zinc ribbon domain 138 168 6.4E-8 T 14-10-2018 IPR015376 Zinc ribbon, NADH pyrophosphatase GO:0016787|GO:0046872 KEGG: 00760+3.6.1.22|MetaCyc: PWY-5381|MetaCyc: PWY-7761 MB46_11975 2e072420dc630eab5be3431684cdef23 325 Gene3D G3DSA:3.90.79.10 171 306 3.3E-31 T 14-10-2018 MB46_11975 2e072420dc630eab5be3431684cdef23 325 ProSitePatterns PS00893 Nudix box signature. 204 225 - T 14-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 MB46_11975 2e072420dc630eab5be3431684cdef23 325 Gene3D G3DSA:3.90.79.20 53 169 2.4E-5 T 14-10-2018 MB46_11975 2e072420dc630eab5be3431684cdef23 325 SUPERFAMILY SSF55811 126 307 5.28E-38 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 MB46_11975 2e072420dc630eab5be3431684cdef23 325 Pfam PF00293 NUDIX domain 173 279 3.1E-15 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MB46_16515 d4ba03b1a8f3b985ff69b13b1403289b 109 Pfam PF12840 Helix-turn-helix domain 12 62 1.8E-12 T 14-10-2018 MB46_16515 d4ba03b1a8f3b985ff69b13b1403289b 109 Gene3D G3DSA:1.10.10.10 5 91 1.3E-16 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_16515 d4ba03b1a8f3b985ff69b13b1403289b 109 SMART SM00418 8 95 5.5E-9 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MB46_16515 d4ba03b1a8f3b985ff69b13b1403289b 109 SUPERFAMILY SSF46785 11 84 5.24E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_12500 05a9d4ade8313d16820c07acdc3361f6 427 Pfam PF00285 Citrate synthase, C-terminal domain 47 413 8.7E-133 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 MB46_12500 05a9d4ade8313d16820c07acdc3361f6 427 ProSitePatterns PS00480 Citrate synthase signature. 305 317 - T 14-10-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 MB46_12500 05a9d4ade8313d16820c07acdc3361f6 427 PRINTS PR00143 Citrate synthase signature 298 318 6.1E-54 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 MB46_12500 05a9d4ade8313d16820c07acdc3361f6 427 PRINTS PR00143 Citrate synthase signature 220 235 6.1E-54 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 MB46_12500 05a9d4ade8313d16820c07acdc3361f6 427 PRINTS PR00143 Citrate synthase signature 242 270 6.1E-54 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 MB46_12500 05a9d4ade8313d16820c07acdc3361f6 427 PRINTS PR00143 Citrate synthase signature 361 377 6.1E-54 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 MB46_12500 05a9d4ade8313d16820c07acdc3361f6 427 PRINTS PR00143 Citrate synthase signature 381 395 6.1E-54 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 MB46_12500 05a9d4ade8313d16820c07acdc3361f6 427 PRINTS PR00143 Citrate synthase signature 166 179 6.1E-54 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 MB46_12500 05a9d4ade8313d16820c07acdc3361f6 427 TIGRFAM TIGR01798 cit_synth_I: citrate (Si)-synthase 15 423 1.6E-179 T 14-10-2018 IPR010953 Citrate synthase, type I GO:0004108|GO:0005737 MB46_12500 05a9d4ade8313d16820c07acdc3361f6 427 Gene3D G3DSA:1.10.580.10 58 413 1.9E-142 T 14-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 MB46_12500 05a9d4ade8313d16820c07acdc3361f6 427 Gene3D G3DSA:2.20.28.60 1 51 1.9E-17 T 14-10-2018 MB46_12500 05a9d4ade8313d16820c07acdc3361f6 427 PIRSF PIRSF001369 38 427 1.5E-155 T 14-10-2018 IPR024176 Citrate synthase, bacterial-type MB46_12500 05a9d4ade8313d16820c07acdc3361f6 427 SUPERFAMILY SSF48256 8 423 2.62E-155 T 14-10-2018 IPR036969 Citrate synthase superfamily GO:0046912 MB46_12500 05a9d4ade8313d16820c07acdc3361f6 427 Gene3D G3DSA:1.10.230.10 269 378 1.9E-142 T 14-10-2018 IPR016143 Citrate synthase-like, small alpha subdomain MB46_06425 fb90b707d75af49c41eec4f38d598387 290 Gene3D G3DSA:3.40.50.720 1 282 2.7E-48 T 14-10-2018 MB46_06425 fb90b707d75af49c41eec4f38d598387 290 SUPERFAMILY SSF51735 1 278 1.08E-52 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_06425 fb90b707d75af49c41eec4f38d598387 290 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 190 1.1E-23 T 14-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 MB46_07905 90d6cdbe6de12cadf0ed9fbf7f78fe36 219 Pfam PF02080 TrkA-C domain 149 216 1.8E-13 T 14-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 MB46_07905 90d6cdbe6de12cadf0ed9fbf7f78fe36 219 PRINTS PR00335 TrkA potassium uptake protein signature 19 33 1.1E-11 T 14-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 MB46_07905 90d6cdbe6de12cadf0ed9fbf7f78fe36 219 PRINTS PR00335 TrkA potassium uptake protein signature 2 16 1.1E-11 T 14-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 MB46_07905 90d6cdbe6de12cadf0ed9fbf7f78fe36 219 PRINTS PR00335 TrkA potassium uptake protein signature 59 69 1.1E-11 T 14-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 MB46_07905 90d6cdbe6de12cadf0ed9fbf7f78fe36 219 PRINTS PR00335 TrkA potassium uptake protein signature 48 58 1.1E-11 T 14-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 MB46_07905 90d6cdbe6de12cadf0ed9fbf7f78fe36 219 PRINTS PR00335 TrkA potassium uptake protein signature 72 86 1.1E-11 T 14-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 MB46_07905 90d6cdbe6de12cadf0ed9fbf7f78fe36 219 SUPERFAMILY SSF116726 147 216 2.09E-13 T 14-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 MB46_07905 90d6cdbe6de12cadf0ed9fbf7f78fe36 219 Gene3D G3DSA:3.40.50.720 3 133 2.6E-31 T 14-10-2018 MB46_07905 90d6cdbe6de12cadf0ed9fbf7f78fe36 219 Gene3D G3DSA:3.30.70.1450 136 217 1.2E-16 T 14-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 MB46_07905 90d6cdbe6de12cadf0ed9fbf7f78fe36 219 Pfam PF02254 TrkA-N domain 3 118 5.9E-25 T 14-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 MB46_07905 90d6cdbe6de12cadf0ed9fbf7f78fe36 219 SUPERFAMILY SSF51735 3 144 2.9E-29 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_12070 4abfae217515012e404d9a72ef6e93e3 395 Gene3D G3DSA:3.40.250.10 295 395 4.4E-25 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily MB46_12070 4abfae217515012e404d9a72ef6e93e3 395 SMART SM00450 299 395 3.9E-22 T 14-10-2018 IPR001763 Rhodanese-like domain MB46_12070 4abfae217515012e404d9a72ef6e93e3 395 Gene3D G3DSA:3.40.50.720 25 272 1.1E-83 T 14-10-2018 MB46_12070 4abfae217515012e404d9a72ef6e93e3 395 Pfam PF00581 Rhodanese-like domain 306 392 7.6E-14 T 14-10-2018 IPR001763 Rhodanese-like domain MB46_12070 4abfae217515012e404d9a72ef6e93e3 395 SUPERFAMILY SSF69572 20 368 7.85E-94 T 14-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 MB46_12070 4abfae217515012e404d9a72ef6e93e3 395 Pfam PF00899 ThiF family 33 264 6.4E-61 T 14-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 MB46_12450 cf9380a39115de70bd2d1da54e1f491e 376 TIGRFAM TIGR01900 dapE-gram_pos: succinyl-diaminopimelate desuccinylase 25 375 7.9E-157 T 14-10-2018 IPR010174 Succinyl-diaminopimelate desuccinylase, DapE GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 MB46_12450 cf9380a39115de70bd2d1da54e1f491e 376 SUPERFAMILY SSF55031 191 291 5.08E-22 T 14-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain MB46_12450 cf9380a39115de70bd2d1da54e1f491e 376 Gene3D G3DSA:3.40.630.10 35 365 7.8E-96 T 14-10-2018 MB46_12450 cf9380a39115de70bd2d1da54e1f491e 376 Pfam PF07687 Peptidase dimerisation domain 191 288 1.5E-17 T 14-10-2018 IPR011650 Peptidase M20, dimerisation domain MB46_12450 cf9380a39115de70bd2d1da54e1f491e 376 SUPERFAMILY SSF53187 31 375 2.57E-42 T 14-10-2018 MB46_12450 cf9380a39115de70bd2d1da54e1f491e 376 Gene3D G3DSA:3.30.70.360 191 299 7.8E-96 T 14-10-2018 MB46_12450 cf9380a39115de70bd2d1da54e1f491e 376 Pfam PF01546 Peptidase family M20/M25/M40 84 375 1.5E-22 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 MB46_15415 7350915b94413e906dc85b7231a9bb5b 112 Gene3D G3DSA:3.30.60.230 1 60 2.4E-26 T 14-10-2018 MB46_15415 7350915b94413e906dc85b7231a9bb5b 112 ProDom PD026347 LSR2-LIKE LSR2 ANTIGEN IMMUNE PRECURSOR RESPONSE SIGNAL PLASMID LYSYL GP61 1 110 8.0E-22 T 14-10-2018 IPR024412 Lsr2 MB46_15415 7350915b94413e906dc85b7231a9bb5b 112 Gene3D G3DSA:1.20.890.50 78 112 1.4E-13 T 14-10-2018 MB46_15415 7350915b94413e906dc85b7231a9bb5b 112 Pfam PF11774 Lsr2 1 110 1.7E-39 T 14-10-2018 IPR024412 Lsr2 MB46_06625 c2ff8e6d8755e283fbc78bb9ab3d7403 261 Gene3D G3DSA:3.90.930.1 14 114 6.9E-6 T 14-10-2018 MB46_06625 c2ff8e6d8755e283fbc78bb9ab3d7403 261 Pfam PF05593 RHS Repeat 171 204 1.6E-6 T 14-10-2018 IPR031325 RHS repeat MB46_06625 c2ff8e6d8755e283fbc78bb9ab3d7403 261 Pfam PF05593 RHS Repeat 17 47 1.2E-6 T 14-10-2018 IPR031325 RHS repeat MB46_06625 c2ff8e6d8755e283fbc78bb9ab3d7403 261 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 72 101 4.4E-4 T 14-10-2018 IPR006530 YD repeat MB46_00485 024195845a3b7e04aada05d6e8ceb5f4 386 SUPERFAMILY SSF56645 5 232 4.06E-69 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 MB46_00485 024195845a3b7e04aada05d6e8ceb5f4 386 SUPERFAMILY SSF47203 236 382 3.87E-38 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 MB46_00485 024195845a3b7e04aada05d6e8ceb5f4 386 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 15 126 4.3E-28 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MB46_00485 024195845a3b7e04aada05d6e8ceb5f4 386 Gene3D G3DSA:2.40.110.10 129 231 1.7E-31 T 14-10-2018 MB46_00485 024195845a3b7e04aada05d6e8ceb5f4 386 Gene3D G3DSA:1.20.140.10 234 386 1.8E-37 T 14-10-2018 MB46_00485 024195845a3b7e04aada05d6e8ceb5f4 386 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 233 379 1.6E-29 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MB46_00485 024195845a3b7e04aada05d6e8ceb5f4 386 Gene3D G3DSA:1.10.540.10 1 127 7.6E-39 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 MB46_00485 024195845a3b7e04aada05d6e8ceb5f4 386 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 130 220 1.3E-22 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MB46_02050 8925b9bc39a658d16aea451a73bb7d58 386 ProSitePatterns PS00106 Galactokinase signature. 30 41 - T 14-10-2018 IPR019741 Galactokinase, conserved site KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 MB46_02050 8925b9bc39a658d16aea451a73bb7d58 386 Gene3D G3DSA:3.30.70.890 204 359 7.7E-126 T 14-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily MB46_02050 8925b9bc39a658d16aea451a73bb7d58 386 SUPERFAMILY SSF55060 210 384 1.78E-47 T 14-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily MB46_02050 8925b9bc39a658d16aea451a73bb7d58 386 PRINTS PR00959 Mevalonate kinase family signature 164 183 2.9E-40 T 14-10-2018 MB46_02050 8925b9bc39a658d16aea451a73bb7d58 386 PRINTS PR00959 Mevalonate kinase family signature 121 143 2.9E-40 T 14-10-2018 MB46_02050 8925b9bc39a658d16aea451a73bb7d58 386 PRINTS PR00959 Mevalonate kinase family signature 331 348 2.9E-40 T 14-10-2018 MB46_02050 8925b9bc39a658d16aea451a73bb7d58 386 PRINTS PR00959 Mevalonate kinase family signature 28 52 2.9E-40 T 14-10-2018 MB46_02050 8925b9bc39a658d16aea451a73bb7d58 386 PIRSF PIRSF000530 3 386 5.6E-118 T 14-10-2018 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 MB46_02050 8925b9bc39a658d16aea451a73bb7d58 386 SUPERFAMILY SSF54211 11 205 2.5E-57 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MB46_02050 8925b9bc39a658d16aea451a73bb7d58 386 Gene3D G3DSA:3.30.230.10 25 203 7.7E-126 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MB46_02050 8925b9bc39a658d16aea451a73bb7d58 386 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 123 134 - T 14-10-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 MB46_02050 8925b9bc39a658d16aea451a73bb7d58 386 TIGRFAM TIGR00131 gal_kin: galactokinase 11 369 3.0E-90 T 14-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 MB46_02050 8925b9bc39a658d16aea451a73bb7d58 386 PRINTS PR00473 Galactokinase signature 268 282 1.8E-25 T 14-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 MB46_02050 8925b9bc39a658d16aea451a73bb7d58 386 PRINTS PR00473 Galactokinase signature 30 48 1.8E-25 T 14-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 MB46_02050 8925b9bc39a658d16aea451a73bb7d58 386 PRINTS PR00473 Galactokinase signature 114 132 1.8E-25 T 14-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 MB46_02050 8925b9bc39a658d16aea451a73bb7d58 386 PRINTS PR00473 Galactokinase signature 94 105 1.8E-25 T 14-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 MB46_02050 8925b9bc39a658d16aea451a73bb7d58 386 Pfam PF00288 GHMP kinases N terminal domain 116 182 9.6E-14 T 14-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 MB46_02050 8925b9bc39a658d16aea451a73bb7d58 386 Pfam PF08544 GHMP kinases C terminal 293 363 2.7E-10 T 14-10-2018 IPR013750 GHMP kinase, C-terminal domain MB46_02050 8925b9bc39a658d16aea451a73bb7d58 386 Pfam PF10509 Galactokinase galactose-binding signature 13 60 1.0E-23 T 14-10-2018 IPR019539 Galactokinase galactose-binding domain GO:0005534 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 MB46_12830 5a59b3e4f873daa4976df9c4a6671748 345 Gene3D G3DSA:3.40.50.2300 169 330 4.2E-74 T 14-10-2018 MB46_12830 5a59b3e4f873daa4976df9c4a6671748 345 Pfam PF13377 Periplasmic binding protein-like domain 179 335 2.5E-35 T 14-10-2018 MB46_12830 5a59b3e4f873daa4976df9c4a6671748 345 Gene3D G3DSA:3.40.50.2300 87 326 4.2E-74 T 14-10-2018 MB46_12830 5a59b3e4f873daa4976df9c4a6671748 345 SMART SM00354 11 81 5.2E-27 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MB46_12830 5a59b3e4f873daa4976df9c4a6671748 345 ProSitePatterns PS00356 LacI-type HTH domain signature. 14 32 - T 14-10-2018 MB46_12830 5a59b3e4f873daa4976df9c4a6671748 345 SUPERFAMILY SSF47413 13 69 3.94E-17 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MB46_12830 5a59b3e4f873daa4976df9c4a6671748 345 Pfam PF00356 Bacterial regulatory proteins, lacI family 14 58 1.4E-17 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MB46_12830 5a59b3e4f873daa4976df9c4a6671748 345 Gene3D G3DSA:1.10.260.40 10 68 1.1E-21 T 14-10-2018 MB46_12830 5a59b3e4f873daa4976df9c4a6671748 345 SUPERFAMILY SSF53822 68 329 1.94E-63 T 14-10-2018 IPR028082 Periplasmic binding protein-like I MB46_08320 70034339d7d61cbd329cb180958a29bc 681 Pfam PF00069 Protein kinase domain 20 263 1.8E-50 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 MB46_08320 70034339d7d61cbd329cb180958a29bc 681 Gene3D G3DSA:3.30.200.20 7 97 7.3E-27 T 14-10-2018 MB46_08320 70034339d7d61cbd329cb180958a29bc 681 SMART SM00740 619 681 1.7E-7 T 14-10-2018 IPR005543 PASTA domain MB46_08320 70034339d7d61cbd329cb180958a29bc 681 SMART SM00740 483 550 1.4E-10 T 14-10-2018 IPR005543 PASTA domain MB46_08320 70034339d7d61cbd329cb180958a29bc 681 SMART SM00740 415 482 5.8E-8 T 14-10-2018 IPR005543 PASTA domain MB46_08320 70034339d7d61cbd329cb180958a29bc 681 SMART SM00740 551 618 2.1E-12 T 14-10-2018 IPR005543 PASTA domain MB46_08320 70034339d7d61cbd329cb180958a29bc 681 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 137 149 - T 14-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 MB46_08320 70034339d7d61cbd329cb180958a29bc 681 Gene3D G3DSA:3.30.10.20 414 483 1.2E-15 T 14-10-2018 MB46_08320 70034339d7d61cbd329cb180958a29bc 681 Gene3D G3DSA:3.30.10.20 555 621 3.4E-15 T 14-10-2018 MB46_08320 70034339d7d61cbd329cb180958a29bc 681 SMART SM00220 18 275 1.2E-60 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 MB46_08320 70034339d7d61cbd329cb180958a29bc 681 Gene3D G3DSA:3.30.10.20 623 681 5.6E-7 T 14-10-2018 MB46_08320 70034339d7d61cbd329cb180958a29bc 681 Gene3D G3DSA:3.30.10.20 487 553 6.5E-17 T 14-10-2018 MB46_08320 70034339d7d61cbd329cb180958a29bc 681 SUPERFAMILY SSF56112 16 274 6.88E-76 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily MB46_08320 70034339d7d61cbd329cb180958a29bc 681 Pfam PF03793 PASTA domain 557 618 9.2E-13 T 14-10-2018 IPR005543 PASTA domain MB46_08320 70034339d7d61cbd329cb180958a29bc 681 Pfam PF03793 PASTA domain 624 680 2.0E-5 T 14-10-2018 IPR005543 PASTA domain MB46_08320 70034339d7d61cbd329cb180958a29bc 681 Pfam PF03793 PASTA domain 488 550 5.0E-11 T 14-10-2018 IPR005543 PASTA domain MB46_08320 70034339d7d61cbd329cb180958a29bc 681 Pfam PF03793 PASTA domain 420 481 3.3E-11 T 14-10-2018 IPR005543 PASTA domain MB46_08320 70034339d7d61cbd329cb180958a29bc 681 Gene3D G3DSA:1.10.510.10 99 286 1.3E-50 T 14-10-2018 MB46_08065 a3ac8895ef5a0c102d01e74c04349850 142 TIGRFAM TIGR03562 osmo_induc_OsmC: peroxiredoxin, OsmC subfamily 4 138 4.3E-48 T 14-10-2018 IPR019904 Peroxiredoxin OsmC GO:0004601|GO:0006979 KEGG: 00480+1.11.1.15 MB46_08065 a3ac8895ef5a0c102d01e74c04349850 142 Gene3D G3DSA:3.30.300.20 2 141 4.4E-31 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta MB46_08065 a3ac8895ef5a0c102d01e74c04349850 142 SUPERFAMILY SSF82784 1 141 4.97E-26 T 14-10-2018 IPR036102 OsmC/Ohr superfamily MB46_08065 a3ac8895ef5a0c102d01e74c04349850 142 Pfam PF02566 OsmC-like protein 45 136 5.1E-14 T 14-10-2018 IPR003718 OsmC/Ohr family MB46_11445 0a47bcc8ad08b7e417cde62ec89d4c89 300 Pfam PF00535 Glycosyl transferase family 2 9 118 1.7E-16 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MB46_11445 0a47bcc8ad08b7e417cde62ec89d4c89 300 Gene3D G3DSA:3.90.550.10 2 204 4.2E-18 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MB46_11445 0a47bcc8ad08b7e417cde62ec89d4c89 300 SUPERFAMILY SSF53448 5 251 1.41E-23 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MB46_01505 7a047ee6bb39ec71e7457e78f54ba193 267 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 41 59 3.9E-11 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MB46_01505 7a047ee6bb39ec71e7457e78f54ba193 267 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 27 41 3.9E-11 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MB46_01505 7a047ee6bb39ec71e7457e78f54ba193 267 Pfam PF08220 DeoR-like helix-turn-helix domain 9 64 7.5E-19 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MB46_01505 7a047ee6bb39ec71e7457e78f54ba193 267 SUPERFAMILY SSF46785 14 66 3.36E-12 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_01505 7a047ee6bb39ec71e7457e78f54ba193 267 Gene3D G3DSA:1.10.10.10 6 59 2.8E-6 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_01505 7a047ee6bb39ec71e7457e78f54ba193 267 Pfam PF00455 DeoR C terminal sensor domain 79 242 1.7E-38 T 14-10-2018 IPR014036 DeoR C-terminal sensor domain MB46_01505 7a047ee6bb39ec71e7457e78f54ba193 267 SUPERFAMILY SSF100950 78 244 1.92E-25 T 14-10-2018 IPR037171 NagB/RpiA transferase-like MB46_01505 7a047ee6bb39ec71e7457e78f54ba193 267 SMART SM01134 77 243 5.7E-41 T 14-10-2018 MB46_01505 7a047ee6bb39ec71e7457e78f54ba193 267 ProSitePatterns PS00894 DeoR-type HTH domain signature. 9 43 - T 14-10-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 MB46_01505 7a047ee6bb39ec71e7457e78f54ba193 267 SMART SM00420 9 61 1.3E-18 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MB46_07325 8a31af95a2c5e798098253e337c982dd 121 Gene3D G3DSA:3.30.1330.40 1 120 1.2E-34 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 MB46_07325 8a31af95a2c5e798098253e337c982dd 121 SUPERFAMILY SSF55298 4 120 1.21E-30 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 MB46_07325 8a31af95a2c5e798098253e337c982dd 121 Pfam PF01042 Endoribonuclease L-PSP 6 119 1.0E-23 T 14-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 MB46_01700 170ac85627b4b64b7c896ce5f96e33d9 740 TIGRFAM TIGR00178 monomer_idh: isocitrate dehydrogenase, NADP-dependent 1 739 0.0 T 14-10-2018 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 MB46_01700 170ac85627b4b64b7c896ce5f96e33d9 740 SUPERFAMILY SSF53659 2 738 0.0 T 14-10-2018 MB46_01700 170ac85627b4b64b7c896ce5f96e33d9 740 PIRSF PIRSF009407 1 739 0.0 T 14-10-2018 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 MB46_01700 170ac85627b4b64b7c896ce5f96e33d9 740 Gene3D G3DSA:3.40.718.10 400 646 3.6E-7 T 14-10-2018 MB46_01700 170ac85627b4b64b7c896ce5f96e33d9 740 Pfam PF03971 Monomeric isocitrate dehydrogenase 3 735 0.0 T 14-10-2018 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 MB46_16865 f1674526523eacd77c4dbd938d579e69 529 SUPERFAMILY SSF52540 37 395 1.44E-50 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_16865 f1674526523eacd77c4dbd938d579e69 529 Pfam PF05872 Bacterial protein of unknown function (DUF853) 36 527 1.8E-175 T 14-10-2018 IPR033186 Helicase HerA-like C-terminal MB46_16865 f1674526523eacd77c4dbd938d579e69 529 Gene3D G3DSA:3.40.50.300 18 106 4.3E-12 T 14-10-2018 MB46_16865 f1674526523eacd77c4dbd938d579e69 529 Gene3D G3DSA:3.40.50.300 200 410 4.3E-21 T 14-10-2018 MB46_12360 177cc829ea88c97e4e8f22eb37981872 103 Pfam PF13601 Winged helix DNA-binding domain 14 92 8.2E-19 T 14-10-2018 IPR027395 Winged helix DNA-binding domain MB46_12360 177cc829ea88c97e4e8f22eb37981872 103 Gene3D G3DSA:1.10.10.10 3 96 1.1E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_12360 177cc829ea88c97e4e8f22eb37981872 103 SUPERFAMILY SSF46785 4 91 8.03E-11 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_11385 22466da9983e68088039cbd11317bd44 308 SMART SM00728 186 224 9.5E-7 T 14-10-2018 IPR006637 Clostridial hydrophobic repeat MB46_11385 22466da9983e68088039cbd11317bd44 308 SMART SM00728 226 270 6.7E-5 T 14-10-2018 IPR006637 Clostridial hydrophobic repeat MB46_11385 22466da9983e68088039cbd11317bd44 308 SMART SM00728 271 308 1.2E-14 T 14-10-2018 IPR006637 Clostridial hydrophobic repeat MB46_11385 22466da9983e68088039cbd11317bd44 308 Pfam PF07538 Clostridial hydrophobic W 272 306 1.7E-17 T 14-10-2018 IPR006637 Clostridial hydrophobic repeat MB46_11385 22466da9983e68088039cbd11317bd44 308 Pfam PF07538 Clostridial hydrophobic W 187 217 3.2E-11 T 14-10-2018 IPR006637 Clostridial hydrophobic repeat MB46_11385 22466da9983e68088039cbd11317bd44 308 Pfam PF07538 Clostridial hydrophobic W 227 259 6.2E-13 T 14-10-2018 IPR006637 Clostridial hydrophobic repeat MB46_11385 22466da9983e68088039cbd11317bd44 308 Pfam PF00188 Cysteine-rich secretory protein family 41 154 5.4E-11 T 14-10-2018 IPR014044 CAP domain MB46_11385 22466da9983e68088039cbd11317bd44 308 Gene3D G3DSA:3.40.33.10 16 156 3.2E-18 T 14-10-2018 IPR035940 CAP superfamily MB46_11385 22466da9983e68088039cbd11317bd44 308 SUPERFAMILY SSF55797 32 155 4.53E-11 T 14-10-2018 IPR035940 CAP superfamily MB46_10185 b45f2d7a29fdd0952e2e6cdb3cf1a79e 528 PIRSF PIRSF012702 25 515 1.9E-140 T 14-10-2018 IPR009197 Microcystin LR degradation protein MlrC MB46_10185 b45f2d7a29fdd0952e2e6cdb3cf1a79e 528 Pfam PF07364 Metallopeptidase family M81 29 316 3.1E-102 T 14-10-2018 IPR015995 Microcystin LR degradation protein MlrC, N-terminal MB46_10185 b45f2d7a29fdd0952e2e6cdb3cf1a79e 528 Pfam PF07171 MlrC C-terminus 327 496 1.2E-55 T 14-10-2018 IPR010799 Microcystin LR degradation protein MlrC, C-terminal MB46_18030 93cedc045ee1c1750afca84a7f68dc04 239 Pfam PF00005 ABC transporter 44 160 5.0E-7 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_18030 93cedc045ee1c1750afca84a7f68dc04 239 Gene3D G3DSA:3.40.50.300 102 208 8.7E-9 T 14-10-2018 MB46_18030 93cedc045ee1c1750afca84a7f68dc04 239 Gene3D G3DSA:3.40.50.300 33 101 1.2E-5 T 14-10-2018 MB46_18030 93cedc045ee1c1750afca84a7f68dc04 239 SMART SM00382 41 211 2.6E-6 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_18030 93cedc045ee1c1750afca84a7f68dc04 239 SUPERFAMILY SSF52540 42 205 5.62E-19 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_11230 d485ef490322a99c284fefa84958cf62 253 SUPERFAMILY SSF88946 61 151 5.69E-24 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 MB46_11230 d485ef490322a99c284fefa84958cf62 253 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 72 232 2.2E-24 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 MB46_11230 d485ef490322a99c284fefa84958cf62 253 TIGRFAM TIGR02947 SigH_actino: RNA polymerase sigma-70 factor, TIGR02947 family 54 243 3.0E-112 T 14-10-2018 IPR014293 RNA polymerase sigma-70, actinobacteria GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MB46_11230 d485ef490322a99c284fefa84958cf62 253 Gene3D G3DSA:1.10.10.10 170 237 6.2E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_11230 d485ef490322a99c284fefa84958cf62 253 Gene3D G3DSA:1.10.1740.10 54 139 7.1E-33 T 14-10-2018 MB46_11230 d485ef490322a99c284fefa84958cf62 253 SUPERFAMILY SSF88659 174 232 2.99E-14 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like MB46_11230 d485ef490322a99c284fefa84958cf62 253 Pfam PF04542 Sigma-70 region 2 73 136 1.2E-17 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 MB46_11230 d485ef490322a99c284fefa84958cf62 253 Pfam PF08281 Sigma-70, region 4 179 228 9.2E-12 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MB46_00260 598d29c49baa79c09c4d59ff3526659e 338 Pfam PF13377 Periplasmic binding protein-like domain 172 333 8.0E-39 T 14-10-2018 MB46_00260 598d29c49baa79c09c4d59ff3526659e 338 Gene3D G3DSA:3.40.50.2300 164 293 1.8E-68 T 14-10-2018 MB46_00260 598d29c49baa79c09c4d59ff3526659e 338 SMART SM00354 5 74 2.4E-7 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MB46_00260 598d29c49baa79c09c4d59ff3526659e 338 Gene3D G3DSA:1.10.260.40 1 49 2.8E-15 T 14-10-2018 MB46_00260 598d29c49baa79c09c4d59ff3526659e 338 Gene3D G3DSA:3.40.50.2300 78 323 1.8E-68 T 14-10-2018 MB46_00260 598d29c49baa79c09c4d59ff3526659e 338 SUPERFAMILY SSF53822 65 336 5.26E-77 T 14-10-2018 IPR028082 Periplasmic binding protein-like I MB46_00260 598d29c49baa79c09c4d59ff3526659e 338 SUPERFAMILY SSF47413 5 53 2.82E-12 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MB46_00260 598d29c49baa79c09c4d59ff3526659e 338 Pfam PF00356 Bacterial regulatory proteins, lacI family 7 50 5.5E-13 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MB46_05980 ce6f56f00a5fe5bc3f0a253c7c44a71c 512 SMART SM00813 291 501 2.7E-59 T 14-10-2018 IPR010720 Alpha-L-arabinofuranosidase, C-terminal GO:0046373|GO:0046556 KEGG: 00520+3.2.1.55 MB46_05980 ce6f56f00a5fe5bc3f0a253c7c44a71c 512 Gene3D G3DSA:2.60.40.1180 6 505 3.2E-210 T 14-10-2018 IPR013780 Glycosyl hydrolase, all-beta MB46_05980 ce6f56f00a5fe5bc3f0a253c7c44a71c 512 Gene3D G3DSA:3.20.20.80 18 387 3.2E-210 T 14-10-2018 MB46_05980 ce6f56f00a5fe5bc3f0a253c7c44a71c 512 SUPERFAMILY SSF51011 368 507 7.55E-28 T 14-10-2018 MB46_05980 ce6f56f00a5fe5bc3f0a253c7c44a71c 512 Pfam PF06964 Alpha-L-arabinofuranosidase C-terminal domain 291 501 1.3E-38 T 14-10-2018 IPR010720 Alpha-L-arabinofuranosidase, C-terminal GO:0046373|GO:0046556 KEGG: 00520+3.2.1.55 MB46_05980 ce6f56f00a5fe5bc3f0a253c7c44a71c 512 SUPERFAMILY SSF51445 18 385 1.56E-109 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily MB46_12610 bb0fb7da3525cea8f6d250c8478f9b44 221 Pfam PF13649 Methyltransferase domain 61 151 1.0E-18 T 14-10-2018 MB46_12610 bb0fb7da3525cea8f6d250c8478f9b44 221 SUPERFAMILY SSF53335 25 206 5.37E-34 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MB46_12610 bb0fb7da3525cea8f6d250c8478f9b44 221 Gene3D G3DSA:3.40.50.150 14 207 6.0E-45 T 14-10-2018 MB46_13460 b283fce0e70a04e85eda393c0a56fefc 704 PRINTS PR00315 GTP-binding elongation factor signature 132 141 2.0E-16 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MB46_13460 b283fce0e70a04e85eda393c0a56fefc 704 PRINTS PR00315 GTP-binding elongation factor signature 80 90 2.0E-16 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MB46_13460 b283fce0e70a04e85eda393c0a56fefc 704 PRINTS PR00315 GTP-binding elongation factor signature 60 68 2.0E-16 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MB46_13460 b283fce0e70a04e85eda393c0a56fefc 704 PRINTS PR00315 GTP-binding elongation factor signature 96 107 2.0E-16 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MB46_13460 b283fce0e70a04e85eda393c0a56fefc 704 PRINTS PR00315 GTP-binding elongation factor signature 14 27 2.0E-16 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MB46_13460 b283fce0e70a04e85eda393c0a56fefc 704 Gene3D G3DSA:3.30.70.870 413 490 7.8E-30 T 14-10-2018 MB46_13460 b283fce0e70a04e85eda393c0a56fefc 704 SMART SM00889 487 608 3.6E-68 T 14-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 MB46_13460 b283fce0e70a04e85eda393c0a56fefc 704 Gene3D G3DSA:3.30.70.240 614 684 5.5E-85 T 14-10-2018 MB46_13460 b283fce0e70a04e85eda393c0a56fefc 704 SUPERFAMILY SSF54980 613 700 1.44E-29 T 14-10-2018 IPR035647 EF-G domain III/V-like MB46_13460 b283fce0e70a04e85eda393c0a56fefc 704 Pfam PF14492 Elongation Factor G, domain II 411 485 1.2E-31 T 14-10-2018 MB46_13460 b283fce0e70a04e85eda393c0a56fefc 704 Pfam PF03764 Elongation factor G, domain IV 486 608 4.2E-46 T 14-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 MB46_13460 b283fce0e70a04e85eda393c0a56fefc 704 SUPERFAMILY SSF52540 8 288 3.38E-109 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_13460 b283fce0e70a04e85eda393c0a56fefc 704 Gene3D G3DSA:3.30.230.10 491 697 5.5E-85 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MB46_13460 b283fce0e70a04e85eda393c0a56fefc 704 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 181 2.8E-37 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MB46_13460 b283fce0e70a04e85eda393c0a56fefc 704 SUPERFAMILY SSF54980 411 488 8.27E-25 T 14-10-2018 IPR035647 EF-G domain III/V-like MB46_13460 b283fce0e70a04e85eda393c0a56fefc 704 Gene3D G3DSA:3.40.50.300 5 297 9.7E-111 T 14-10-2018 MB46_13460 b283fce0e70a04e85eda393c0a56fefc 704 TIGRFAM TIGR00484 EF-G: translation elongation factor G 7 701 0.0 T 14-10-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MB46_13460 b283fce0e70a04e85eda393c0a56fefc 704 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 53 68 - T 14-10-2018 IPR031157 Tr-type G domain, conserved site MB46_13460 b283fce0e70a04e85eda393c0a56fefc 704 Pfam PF03144 Elongation factor Tu domain 2 331 398 3.9E-13 T 14-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 MB46_13460 b283fce0e70a04e85eda393c0a56fefc 704 Hamap MF_00054_B Elongation factor G [fusA]. 8 701 108.758 T 14-10-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MB46_13460 b283fce0e70a04e85eda393c0a56fefc 704 SMART SM00838 610 697 4.9E-54 T 14-10-2018 IPR000640 Elongation factor EFG, domain V-like MB46_13460 b283fce0e70a04e85eda393c0a56fefc 704 SUPERFAMILY SSF50447 271 411 1.74E-32 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily MB46_13460 b283fce0e70a04e85eda393c0a56fefc 704 Gene3D G3DSA:2.40.30.10 298 412 2.4E-43 T 14-10-2018 MB46_13460 b283fce0e70a04e85eda393c0a56fefc 704 Pfam PF00679 Elongation factor G C-terminus 610 696 5.2E-30 T 14-10-2018 IPR000640 Elongation factor EFG, domain V-like MB46_13460 b283fce0e70a04e85eda393c0a56fefc 704 Pfam PF00009 Elongation factor Tu GTP binding domain 11 287 4.6E-68 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MB46_13460 b283fce0e70a04e85eda393c0a56fefc 704 SUPERFAMILY SSF54211 486 609 9.61E-39 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MB46_14595 b2c12cfe5a07c4ea514ed61e7ca1fb79 295 TIGRFAM TIGR00751 menA: 1,4-dihydroxy-2-naphthoate octaprenyltransferase 12 285 2.2E-81 T 14-10-2018 MB46_14595 b2c12cfe5a07c4ea514ed61e7ca1fb79 295 Pfam PF01040 UbiA prenyltransferase family 20 264 2.6E-34 T 14-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 MB46_14595 b2c12cfe5a07c4ea514ed61e7ca1fb79 295 Hamap MF_01937 1,4-dihydroxy-2-naphthoate octaprenyltransferase [menA]. 3 287 21.74 T 14-10-2018 IPR004657 1,4-dihydroxy-2-naphthoate octaprenyltransferase GO:0009234|GO:0016021|GO:0046428 KEGG: 00130+2.5.1.74|MetaCyc: PWY-5839|MetaCyc: PWY-5851|MetaCyc: PWY-5852|MetaCyc: PWY-5853|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 MB46_14595 b2c12cfe5a07c4ea514ed61e7ca1fb79 295 PIRSF PIRSF005355 1 292 3.7E-86 T 14-10-2018 IPR026046 UbiA prenyltransferase domain containing protein 1 GO:0004659 Reactome: R-HSA-6806664 MB46_12800 504e9e7f49d2aa66779e38f963e0315d 668 Pfam PF02720 Domain of unknown function (DUF222) 18 226 8.7E-6 T 14-10-2018 IPR003870 Domain of unknown function DUF222 MB46_12800 504e9e7f49d2aa66779e38f963e0315d 668 Gene3D G3DSA:3.30.40.60 519 605 3.9E-8 T 14-10-2018 MB46_12800 504e9e7f49d2aa66779e38f963e0315d 668 Pfam PF01844 HNH endonuclease 545 585 9.5E-5 T 14-10-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 MB46_09015 6edfcdd03d70dcb719e03a7af2ba4f6d 162 Gene3D G3DSA:3.40.1350.140 8 160 1.6E-43 T 14-10-2018 IPR038231 MepB-like superfamily MB46_09015 6edfcdd03d70dcb719e03a7af2ba4f6d 162 Pfam PF08877 MepB protein 27 147 2.6E-41 T 14-10-2018 IPR011235 MepB-like MB46_11200 18b51faafe9ab55681fa5c87b562be75 1262 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 142 373 3.9E-51 T 14-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 MB46_11200 18b51faafe9ab55681fa5c87b562be75 1262 SMART SM00861 923 1116 4.2E-49 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain MB46_11200 18b51faafe9ab55681fa5c87b562be75 1262 Pfam PF16870 2-oxoglutarate dehydrogenase C-terminal 1121 1259 4.1E-41 T 14-10-2018 IPR031717 Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 MB46_11200 18b51faafe9ab55681fa5c87b562be75 1262 SUPERFAMILY SSF52518 912 1123 1.86E-44 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold MB46_11200 18b51faafe9ab55681fa5c87b562be75 1262 SUPERFAMILY SSF52518 473 856 3.11E-84 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold MB46_11200 18b51faafe9ab55681fa5c87b562be75 1262 Gene3D G3DSA:3.40.50.12470 887 1132 4.1E-153 T 14-10-2018 MB46_11200 18b51faafe9ab55681fa5c87b562be75 1262 Gene3D G3DSA:3.40.50.11610 1053 1256 4.1E-153 T 14-10-2018 MB46_11200 18b51faafe9ab55681fa5c87b562be75 1262 Pfam PF00676 Dehydrogenase E1 component 530 847 1.7E-55 T 14-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 MB46_11200 18b51faafe9ab55681fa5c87b562be75 1262 Gene3D G3DSA:1.10.287.1150 404 485 2.0E-25 T 14-10-2018 MB46_11200 18b51faafe9ab55681fa5c87b562be75 1262 Gene3D G3DSA:3.30.559.10 122 383 1.2E-50 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 MB46_11200 18b51faafe9ab55681fa5c87b562be75 1262 PIRSF PIRSF000157 3 1261 0.0 T 14-10-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 MB46_11200 18b51faafe9ab55681fa5c87b562be75 1262 Pfam PF02779 Transketolase, pyrimidine binding domain 923 1115 7.8E-55 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain MB46_11200 18b51faafe9ab55681fa5c87b562be75 1262 Pfam PF16078 2-oxoglutarate dehydrogenase N-terminus 13 47 9.8E-8 T 14-10-2018 IPR032106 2-oxoglutarate dehydrogenase E1 component, N-terminal domain KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 MB46_11200 18b51faafe9ab55681fa5c87b562be75 1262 TIGRFAM TIGR00239 2oxo_dh_E1: oxoglutarate dehydrogenase (succinyl-transferring), E1 component 401 1258 1.5E-299 T 14-10-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 MB46_11200 18b51faafe9ab55681fa5c87b562be75 1262 SUPERFAMILY SSF52777 136 372 1.16E-54 T 14-10-2018 MB46_11200 18b51faafe9ab55681fa5c87b562be75 1262 Gene3D G3DSA:3.40.50.970 487 849 1.4E-146 T 14-10-2018 MB46_12190 356e6e5948214b6b563fb7b352a7340b 425 Pfam PF11799 impB/mucB/samB family C-terminal domain 243 354 5.8E-8 T 14-10-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 MB46_12190 356e6e5948214b6b563fb7b352a7340b 425 Gene3D G3DSA:3.30.70.270 6 158 1.7E-35 T 14-10-2018 MB46_12190 356e6e5948214b6b563fb7b352a7340b 425 SUPERFAMILY SSF56672 5 240 1.87E-58 T 14-10-2018 MB46_12190 356e6e5948214b6b563fb7b352a7340b 425 Gene3D G3DSA:1.10.150.20 176 232 3.1E-9 T 14-10-2018 MB46_12190 356e6e5948214b6b563fb7b352a7340b 425 Pfam PF00817 impB/mucB/samB family 9 152 1.6E-27 T 14-10-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 MB46_12190 356e6e5948214b6b563fb7b352a7340b 425 Gene3D G3DSA:2.30.40.20 14 77 1.7E-35 T 14-10-2018 MB46_12190 356e6e5948214b6b563fb7b352a7340b 425 Pfam PF13438 Domain of unknown function (DUF4113) 381 423 2.2E-13 T 14-10-2018 IPR025188 Domain of unknown function DUF4113 MB46_07675 661d1808e857f20a75fd5786079e2142 281 Gene3D G3DSA:3.30.70.120 209 275 2.8E-26 T 14-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal MB46_07675 661d1808e857f20a75fd5786079e2142 281 Gene3D G3DSA:3.40.190.10 92 176 1.3E-25 T 14-10-2018 MB46_07675 661d1808e857f20a75fd5786079e2142 281 Pfam PF01634 ATP phosphoribosyltransferase 49 201 7.3E-41 T 14-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 MB46_07675 661d1808e857f20a75fd5786079e2142 281 Hamap MF_00079 ATP phosphoribosyltransferase [hisG]. 1 281 32.111 T 14-10-2018 IPR020621 ATP phosphoribosyltransferase HisG, long form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 MB46_07675 661d1808e857f20a75fd5786079e2142 281 Gene3D G3DSA:3.40.190.10 1 91 1.8E-26 T 14-10-2018 MB46_07675 661d1808e857f20a75fd5786079e2142 281 SUPERFAMILY SSF53850 1 206 7.97E-61 T 14-10-2018 MB46_07675 661d1808e857f20a75fd5786079e2142 281 TIGRFAM TIGR03455 HisG_C-term: ATP phosphoribosyltransferase, C-terminal domain 193 280 2.1E-28 T 14-10-2018 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 MB46_07675 661d1808e857f20a75fd5786079e2142 281 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 2 182 5.1E-52 T 14-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 MB46_07675 661d1808e857f20a75fd5786079e2142 281 SUPERFAMILY SSF54913 208 280 8.89E-22 T 14-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta MB46_07675 661d1808e857f20a75fd5786079e2142 281 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 141 162 - T 14-10-2018 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17 MB46_07675 661d1808e857f20a75fd5786079e2142 281 Pfam PF08029 HisG, C-terminal domain 206 277 5.6E-26 T 14-10-2018 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 MB46_10165 c09cce54d662a8270ff2c7f37921ac59 526 Gene3D G3DSA:2.170.220.10 122 235 2.8E-151 T 14-10-2018 MB46_10165 c09cce54d662a8270ff2c7f37921ac59 526 SUPERFAMILY SSF47323 359 517 7.66E-38 T 14-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 MB46_10165 c09cce54d662a8270ff2c7f37921ac59 526 Gene3D G3DSA:3.40.50.620 11 343 2.8E-151 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MB46_10165 c09cce54d662a8270ff2c7f37921ac59 526 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 20 29 - T 14-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 MB46_10165 c09cce54d662a8270ff2c7f37921ac59 526 Hamap MF_01228 Methionine--tRNA ligase [metG]. 6 517 45.551 T 14-10-2018 IPR023457 Methionine-tRNA synthetase, type 2 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 MB46_10165 c09cce54d662a8270ff2c7f37921ac59 526 SUPERFAMILY SSF52374 9 361 3.22E-113 T 14-10-2018 MB46_10165 c09cce54d662a8270ff2c7f37921ac59 526 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 12 490 1.1E-156 T 14-10-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 MB46_10165 c09cce54d662a8270ff2c7f37921ac59 526 PRINTS PR01041 Methionyl-tRNA synthetase signature 93 104 2.0E-33 T 14-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 MB46_10165 c09cce54d662a8270ff2c7f37921ac59 526 PRINTS PR01041 Methionyl-tRNA synthetase signature 266 281 2.0E-33 T 14-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 MB46_10165 c09cce54d662a8270ff2c7f37921ac59 526 PRINTS PR01041 Methionyl-tRNA synthetase signature 13 26 2.0E-33 T 14-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 MB46_10165 c09cce54d662a8270ff2c7f37921ac59 526 PRINTS PR01041 Methionyl-tRNA synthetase signature 358 369 2.0E-33 T 14-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 MB46_10165 c09cce54d662a8270ff2c7f37921ac59 526 PRINTS PR01041 Methionyl-tRNA synthetase signature 233 244 2.0E-33 T 14-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 MB46_10165 c09cce54d662a8270ff2c7f37921ac59 526 PRINTS PR01041 Methionyl-tRNA synthetase signature 45 59 2.0E-33 T 14-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 MB46_10165 c09cce54d662a8270ff2c7f37921ac59 526 Pfam PF09334 tRNA synthetases class I (M) 11 370 4.1E-112 T 14-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 MB46_10165 c09cce54d662a8270ff2c7f37921ac59 526 Gene3D G3DSA:1.10.730.10 348 522 6.5E-48 T 14-10-2018 MB46_09525 d601862eeb3a084ff0d0f395f90937c1 528 Pfam PF00171 Aldehyde dehydrogenase family 25 504 3.0E-153 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 MB46_09525 d601862eeb3a084ff0d0f395f90937c1 528 Gene3D G3DSA:3.40.605.10 23 498 2.5E-166 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 MB46_09525 d601862eeb3a084ff0d0f395f90937c1 528 Gene3D G3DSA:3.40.309.10 265 474 2.5E-166 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 MB46_09525 d601862eeb3a084ff0d0f395f90937c1 528 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 260 267 - T 14-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 MB46_09525 d601862eeb3a084ff0d0f395f90937c1 528 SUPERFAMILY SSF53720 14 507 5.37E-152 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 MB46_09525 d601862eeb3a084ff0d0f395f90937c1 528 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 288 299 - T 14-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 MB46_08215 0721ace27a2871c5449f1a13a07a3d55 247 Pfam PF01168 Alanine racemase, N-terminal domain 15 244 2.9E-10 T 14-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MB46_08215 0721ace27a2871c5449f1a13a07a3d55 247 SUPERFAMILY SSF51419 4 241 1.86E-50 T 14-10-2018 IPR029066 PLP-binding barrel MB46_08215 0721ace27a2871c5449f1a13a07a3d55 247 Hamap MF_02087 Pyridoxal phosphate homeostasis protein. 13 242 23.077 T 14-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 MB46_08215 0721ace27a2871c5449f1a13a07a3d55 247 Gene3D G3DSA:3.20.20.10 1 245 3.4E-63 T 14-10-2018 IPR029066 PLP-binding barrel MB46_08215 0721ace27a2871c5449f1a13a07a3d55 247 PIRSF PIRSF004848 3 246 9.6E-49 T 14-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 MB46_08215 0721ace27a2871c5449f1a13a07a3d55 247 ProSitePatterns PS01211 Uncharacterized protein family UPF0001 signature. 79 93 - T 14-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 MB46_10910 92595be4c5b8458a182455253f76da61 135 SUPERFAMILY SSF51182 8 132 3.46E-25 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily MB46_10910 92595be4c5b8458a182455253f76da61 135 Gene3D G3DSA:2.60.120.10 3 132 6.0E-43 T 14-10-2018 IPR014710 RmlC-like jelly roll fold MB46_10910 92595be4c5b8458a182455253f76da61 135 Pfam PF07883 Cupin domain 39 96 4.5E-15 T 14-10-2018 IPR013096 Cupin 2, conserved barrel MB46_09245 c93c4390a6a174d738bbc7dbe7fd2304 241 SUPERFAMILY SSF52540 17 221 1.34E-38 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_09245 c93c4390a6a174d738bbc7dbe7fd2304 241 PIRSF PIRSF006755 15 233 1.2E-40 T 14-10-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 MB46_09245 c93c4390a6a174d738bbc7dbe7fd2304 241 Gene3D G3DSA:3.40.50.300 15 241 1.3E-60 T 14-10-2018 MB46_09245 c93c4390a6a174d738bbc7dbe7fd2304 241 TIGRFAM TIGR00347 bioD: dethiobiotin synthase 18 188 1.0E-38 T 14-10-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 MB46_09245 c93c4390a6a174d738bbc7dbe7fd2304 241 Pfam PF13500 AAA domain 17 222 2.5E-35 T 14-10-2018 MB46_09245 c93c4390a6a174d738bbc7dbe7fd2304 241 Hamap MF_00336 ATP-dependent dethiobiotin synthetase BioD [bioD]. 14 223 24.206 T 14-10-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 MB46_16070 ab988c2050717a3b5e28f6256cbfc45e 337 SMART SM00470 73 166 1.1E-32 T 14-10-2018 IPR003115 ParB/Sulfiredoxin MB46_16070 ab988c2050717a3b5e28f6256cbfc45e 337 SUPERFAMILY SSF109709 158 268 6.8E-34 T 14-10-2018 MB46_16070 ab988c2050717a3b5e28f6256cbfc45e 337 SUPERFAMILY SSF110849 62 169 7.5E-30 T 14-10-2018 IPR036086 ParB/Sulfiredoxin superfamily MB46_16070 ab988c2050717a3b5e28f6256cbfc45e 337 Gene3D G3DSA:1.10.10.2830 153 266 4.0E-36 T 14-10-2018 MB46_16070 ab988c2050717a3b5e28f6256cbfc45e 337 Pfam PF02195 ParB-like nuclease domain 74 165 2.2E-23 T 14-10-2018 IPR003115 ParB/Sulfiredoxin MB46_16070 ab988c2050717a3b5e28f6256cbfc45e 337 Gene3D G3DSA:3.90.1530.30 86 152 3.6E-26 T 14-10-2018 MB46_16070 ab988c2050717a3b5e28f6256cbfc45e 337 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 72 251 2.4E-59 T 14-10-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 MB46_15730 9c851d32cfecf81078bcb8779c20a698 173 Pfam PF04978 Protein of unknown function (DUF664) 15 165 8.2E-16 T 14-10-2018 IPR007061 Protein of unknown function DUF664 MB46_15730 9c851d32cfecf81078bcb8779c20a698 173 SUPERFAMILY SSF109854 5 165 1.34E-28 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes MB46_15730 9c851d32cfecf81078bcb8779c20a698 173 Gene3D G3DSA:1.20.120.450 1 167 1.3E-58 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes MB46_12035 36adcf54bbd303242b8d4f7164f3efe4 327 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 240 312 4.0E-18 T 14-10-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MB46_12035 36adcf54bbd303242b8d4f7164f3efe4 327 PRINTS PR00151 Porphobilinogen deaminase signature 139 156 2.1E-23 T 14-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MB46_12035 36adcf54bbd303242b8d4f7164f3efe4 327 PRINTS PR00151 Porphobilinogen deaminase signature 41 61 2.1E-23 T 14-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MB46_12035 36adcf54bbd303242b8d4f7164f3efe4 327 PRINTS PR00151 Porphobilinogen deaminase signature 72 91 2.1E-23 T 14-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MB46_12035 36adcf54bbd303242b8d4f7164f3efe4 327 PRINTS PR00151 Porphobilinogen deaminase signature 120 137 2.1E-23 T 14-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MB46_12035 36adcf54bbd303242b8d4f7164f3efe4 327 Gene3D G3DSA:3.30.160.40 235 321 2.5E-21 T 14-10-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MB46_12035 36adcf54bbd303242b8d4f7164f3efe4 327 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 4 313 2.3E-88 T 14-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MB46_12035 36adcf54bbd303242b8d4f7164f3efe4 327 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 3 314 32.677 T 14-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MB46_12035 36adcf54bbd303242b8d4f7164f3efe4 327 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 4 222 3.1E-65 T 14-10-2018 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MB46_12035 36adcf54bbd303242b8d4f7164f3efe4 327 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 245 261 - T 14-10-2018 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MB46_12035 36adcf54bbd303242b8d4f7164f3efe4 327 Gene3D G3DSA:3.40.190.10 4 225 1.3E-70 T 14-10-2018 MB46_12035 36adcf54bbd303242b8d4f7164f3efe4 327 SUPERFAMILY SSF54782 234 319 1.57E-19 T 14-10-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MB46_12035 36adcf54bbd303242b8d4f7164f3efe4 327 SUPERFAMILY SSF53850 3 226 1.85E-62 T 14-10-2018 MB46_12035 36adcf54bbd303242b8d4f7164f3efe4 327 Gene3D G3DSA:3.40.190.10 96 209 1.3E-70 T 14-10-2018 MB46_12035 36adcf54bbd303242b8d4f7164f3efe4 327 PIRSF PIRSF001438 1 327 2.9E-105 T 14-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MB46_07055 6ff7b385f8a2cae9f7d2db276a9dca3b 500 Gene3D G3DSA:1.20.1740.10 21 475 2.9E-32 T 14-10-2018 MB46_07055 6ff7b385f8a2cae9f7d2db276a9dca3b 500 PIRSF PIRSF006060 10 490 2.6E-55 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 MB46_07055 6ff7b385f8a2cae9f7d2db276a9dca3b 500 Pfam PF13520 Amino acid permease 31 462 3.5E-28 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 MB46_12040 fc19bb5db9bba9f2f5ac16fcd180f388 389 Gene3D G3DSA:3.40.50.1400 14 331 2.6E-115 T 14-10-2018 MB46_12040 fc19bb5db9bba9f2f5ac16fcd180f388 389 Gene3D G3DSA:3.40.50.1400 155 316 2.6E-115 T 14-10-2018 MB46_12040 fc19bb5db9bba9f2f5ac16fcd180f388 389 Hamap MF_00323 Ferrochelatase [hemH]. 10 335 28.295 T 14-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 MB46_12040 fc19bb5db9bba9f2f5ac16fcd180f388 389 SUPERFAMILY SSF53800 10 365 1.08E-76 T 14-10-2018 MB46_12040 fc19bb5db9bba9f2f5ac16fcd180f388 389 Pfam PF00762 Ferrochelatase 12 334 4.5E-92 T 14-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 MB46_06775 4224ce04f888fcab67d22d421c46bc6e 205 SUPERFAMILY SSF48498 90 188 2.49E-13 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily MB46_06775 4224ce04f888fcab67d22d421c46bc6e 205 Pfam PF13305 WHG domain 94 175 6.3E-11 T 14-10-2018 IPR025996 WHG domain MB46_06775 4224ce04f888fcab67d22d421c46bc6e 205 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 61 1.4E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MB46_06775 4224ce04f888fcab67d22d421c46bc6e 205 SUPERFAMILY SSF46689 5 77 7.28E-16 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MB46_06775 4224ce04f888fcab67d22d421c46bc6e 205 Gene3D G3DSA:1.10.357.10 3 199 1.2E-62 T 14-10-2018 MB46_16230 58ee9a6308d5d2f6dc269ab8d7eb9e26 161 Pfam PF16697 Inner membrane component of T3SS, cytoplasmic domain 72 160 1.2E-13 T 14-10-2018 IPR032030 YscD, cytoplasmic domain MB46_16230 58ee9a6308d5d2f6dc269ab8d7eb9e26 161 SUPERFAMILY SSF49879 59 159 1.63E-22 T 14-10-2018 IPR008984 SMAD/FHA domain superfamily GO:0005515 MB46_16230 58ee9a6308d5d2f6dc269ab8d7eb9e26 161 Gene3D G3DSA:2.60.200.20 31 160 2.7E-25 T 14-10-2018 MB46_16230 58ee9a6308d5d2f6dc269ab8d7eb9e26 161 SMART SM00240 88 138 1.0E-10 T 14-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 MB46_00425 462d07673ea1ebf623b818c53ef47daf 445 SUPERFAMILY SSF53850 24 439 9.66E-59 T 14-10-2018 MB46_00425 462d07673ea1ebf623b818c53ef47daf 445 Pfam PF01547 Bacterial extracellular solute-binding protein 62 355 6.8E-25 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein MB46_00425 462d07673ea1ebf623b818c53ef47daf 445 Gene3D G3DSA:3.40.190.10 63 400 3.7E-79 T 14-10-2018 MB46_00425 462d07673ea1ebf623b818c53ef47daf 445 Gene3D G3DSA:3.40.190.10 164 431 3.7E-79 T 14-10-2018 MB46_13045 399f4c343c3c80a14c3b27b638c57780 201 PRINTS PR01415 Ankyrin repeat signature 155 169 7.3E-5 T 14-10-2018 IPR002110 Ankyrin repeat GO:0005515 MB46_13045 399f4c343c3c80a14c3b27b638c57780 201 PRINTS PR01415 Ankyrin repeat signature 102 117 7.3E-5 T 14-10-2018 IPR002110 Ankyrin repeat GO:0005515 MB46_13045 399f4c343c3c80a14c3b27b638c57780 201 SMART SM00248 101 130 23.0 T 14-10-2018 IPR002110 Ankyrin repeat GO:0005515 MB46_13045 399f4c343c3c80a14c3b27b638c57780 201 SMART SM00248 35 64 8.8 T 14-10-2018 IPR002110 Ankyrin repeat GO:0005515 MB46_13045 399f4c343c3c80a14c3b27b638c57780 201 SMART SM00248 2 31 3000.0 T 14-10-2018 IPR002110 Ankyrin repeat GO:0005515 MB46_13045 399f4c343c3c80a14c3b27b638c57780 201 SMART SM00248 134 168 5.8 T 14-10-2018 IPR002110 Ankyrin repeat GO:0005515 MB46_13045 399f4c343c3c80a14c3b27b638c57780 201 Pfam PF12796 Ankyrin repeats (3 copies) 85 170 2.0E-10 T 14-10-2018 IPR020683 Ankyrin repeat-containing domain MB46_13045 399f4c343c3c80a14c3b27b638c57780 201 SUPERFAMILY SSF48403 5 197 5.43E-38 T 14-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily MB46_13045 399f4c343c3c80a14c3b27b638c57780 201 Gene3D G3DSA:1.25.40.20 2 198 3.0E-43 T 14-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily MB46_16550 a39c365527f6f306b29adefc9b1c6399 504 Pfam PF07819 PGAP1-like protein 293 374 3.5E-7 T 14-10-2018 IPR012908 GPI inositol-deacylase PGAP1-like GO:0016788 Reactome: R-HSA-162791 MB46_16550 a39c365527f6f306b29adefc9b1c6399 504 SUPERFAMILY SSF53474 259 394 8.02E-10 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_16550 a39c365527f6f306b29adefc9b1c6399 504 Gene3D G3DSA:3.40.50.1820 291 436 3.2E-6 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_11815 a6492bdcdb180d351109a400f0ccf46f 283 SUPERFAMILY SSF51430 15 272 4.85E-85 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily MB46_11815 a6492bdcdb180d351109a400f0ccf46f 283 PRINTS PR00069 Aldo-keto reductase signature 98 116 1.8E-44 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MB46_11815 a6492bdcdb180d351109a400f0ccf46f 283 PRINTS PR00069 Aldo-keto reductase signature 201 225 1.8E-44 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MB46_11815 a6492bdcdb180d351109a400f0ccf46f 283 PRINTS PR00069 Aldo-keto reductase signature 130 147 1.8E-44 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MB46_11815 a6492bdcdb180d351109a400f0ccf46f 283 PRINTS PR00069 Aldo-keto reductase signature 44 68 1.8E-44 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MB46_11815 a6492bdcdb180d351109a400f0ccf46f 283 PRINTS PR00069 Aldo-keto reductase signature 164 193 1.8E-44 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MB46_11815 a6492bdcdb180d351109a400f0ccf46f 283 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 130 147 - T 14-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 MB46_11815 a6492bdcdb180d351109a400f0ccf46f 283 Pfam PF00248 Aldo/keto reductase family 31 199 3.5E-35 T 14-10-2018 IPR023210 NADP-dependent oxidoreductase domain MB46_11815 a6492bdcdb180d351109a400f0ccf46f 283 Pfam PF00248 Aldo/keto reductase family 206 265 3.8E-8 T 14-10-2018 IPR023210 NADP-dependent oxidoreductase domain MB46_11815 a6492bdcdb180d351109a400f0ccf46f 283 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 48 65 - T 14-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 MB46_11815 a6492bdcdb180d351109a400f0ccf46f 283 Gene3D G3DSA:3.20.20.100 2 280 2.1E-101 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily MB46_11815 a6492bdcdb180d351109a400f0ccf46f 283 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 234 249 - T 14-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 MB46_11815 a6492bdcdb180d351109a400f0ccf46f 283 PIRSF PIRSF000097 9 279 3.3E-72 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MB46_06195 55f4ec98b1d6bf89face6d857b97e29a 155 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 118 137 9.4E-40 T 14-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 MB46_06195 55f4ec98b1d6bf89face6d857b97e29a 155 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 32 50 9.4E-40 T 14-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 MB46_06195 55f4ec98b1d6bf89face6d857b97e29a 155 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 53 71 9.4E-40 T 14-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 MB46_06195 55f4ec98b1d6bf89face6d857b97e29a 155 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 9 27 9.4E-40 T 14-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 MB46_06195 55f4ec98b1d6bf89face6d857b97e29a 155 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 77 95 9.4E-40 T 14-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 MB46_06195 55f4ec98b1d6bf89face6d857b97e29a 155 ProDom PD013172 LYASE SYNTHESIS LUXS AUTOINDUCER-2 PRODUCTION AUTOINDUCER S-RIBOSYLHOMOCYSTEINE AI-2 QUORUM SENSING 12 144 2.0E-50 T 14-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 MB46_06195 55f4ec98b1d6bf89face6d857b97e29a 155 Hamap MF_00091 S-ribosylhomocysteine lyase [luxS]. 5 155 33.652 T 14-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 MB46_06195 55f4ec98b1d6bf89face6d857b97e29a 155 SUPERFAMILY SSF63411 5 152 1.92E-58 T 14-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 MB46_06195 55f4ec98b1d6bf89face6d857b97e29a 155 PIRSF PIRSF006160 5 155 1.8E-59 T 14-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 MB46_06195 55f4ec98b1d6bf89face6d857b97e29a 155 Pfam PF02664 S-Ribosylhomocysteinase (LuxS) 7 151 1.1E-53 T 14-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 MB46_06195 55f4ec98b1d6bf89face6d857b97e29a 155 Gene3D G3DSA:3.30.1360.80 4 155 2.3E-59 T 14-10-2018 IPR037005 S-ribosylhomocysteinase (LuxS) superfamily GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 MB46_01015 37a85303805af03bc0e68062406f29e4 277 Pfam PF02634 FdhD/NarQ family 28 276 3.1E-79 T 14-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 MB46_01015 37a85303805af03bc0e68062406f29e4 277 SUPERFAMILY SSF53927 17 276 7.82E-76 T 14-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 MB46_01015 37a85303805af03bc0e68062406f29e4 277 TIGRFAM TIGR00129 fdhD_narQ: formate dehydrogenase family accessory protein FdhD 24 276 8.0E-50 T 14-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 MB46_01015 37a85303805af03bc0e68062406f29e4 277 PIRSF PIRSF015626 1 277 6.5E-85 T 14-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 MB46_01015 37a85303805af03bc0e68062406f29e4 277 Gene3D G3DSA:3.40.140.10 130 277 1.0E-52 T 14-10-2018 MB46_01015 37a85303805af03bc0e68062406f29e4 277 Hamap MF_00187 Sulfur carrier protein FdhD [fdhD]. 2 277 33.839 T 14-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 MB46_01015 37a85303805af03bc0e68062406f29e4 277 Gene3D G3DSA:3.10.20.10 30 121 4.7E-5 T 14-10-2018 MB46_17525 f31f5d40f367734a429baa0835a64fe7 222 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 7 22 7.7E-12 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MB46_17525 f31f5d40f367734a429baa0835a64fe7 222 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 39 54 7.7E-12 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MB46_17525 f31f5d40f367734a429baa0835a64fe7 222 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 54 69 7.7E-12 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MB46_17525 f31f5d40f367734a429baa0835a64fe7 222 SUPERFAMILY SSF46785 5 84 1.07E-23 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_17525 f31f5d40f367734a429baa0835a64fe7 222 SMART SM00418 5 82 2.0E-21 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MB46_17525 f31f5d40f367734a429baa0835a64fe7 222 Gene3D G3DSA:1.10.10.10 2 100 6.1E-26 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_17525 f31f5d40f367734a429baa0835a64fe7 222 Pfam PF01022 Bacterial regulatory protein, arsR family 13 57 4.1E-17 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MB46_12685 35dc15db9fa936790c2ebd3d5661b8f9 405 SUPERFAMILY SSF53383 7 402 8.07E-96 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MB46_12685 35dc15db9fa936790c2ebd3d5661b8f9 405 Gene3D G3DSA:3.90.1150.10 21 399 3.4E-138 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MB46_12685 35dc15db9fa936790c2ebd3d5661b8f9 405 Gene3D G3DSA:3.40.640.10 53 295 3.4E-138 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MB46_12685 35dc15db9fa936790c2ebd3d5661b8f9 405 Pfam PF00155 Aminotransferase class I and II 61 396 3.8E-49 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MB46_12695 6181578bd80372d23f1add6f7ebf1188 606 Gene3D G3DSA:3.20.20.80 2 278 3.3E-95 T 14-10-2018 MB46_12695 6181578bd80372d23f1add6f7ebf1188 606 Gene3D G3DSA:2.60.120.260 358 490 3.4E-85 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily MB46_12695 6181578bd80372d23f1add6f7ebf1188 606 ProSitePatterns PS01182 Glycosyl hydrolases family 35 putative active site. 154 166 - T 14-10-2018 IPR019801 Glycoside hydrolase, family 35, conserved site GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 MB46_12695 6181578bd80372d23f1add6f7ebf1188 606 SUPERFAMILY SSF49785 451 584 2.07E-25 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily MB46_12695 6181578bd80372d23f1add6f7ebf1188 606 SUPERFAMILY SSF51445 11 328 5.05E-88 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily MB46_12695 6181578bd80372d23f1add6f7ebf1188 606 Gene3D G3DSA:2.60.120.260 279 580 3.4E-85 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily MB46_12695 6181578bd80372d23f1add6f7ebf1188 606 Pfam PF01301 Glycosyl hydrolases family 35 16 328 2.0E-103 T 14-10-2018 IPR031330 Glycoside hydrolase 35, catalytic domain KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 MB46_12695 6181578bd80372d23f1add6f7ebf1188 606 PIRSF PIRSF006336 1 603 3.5E-208 T 14-10-2018 IPR026283 Beta-galactosidase 1-like GO:0004565 MB46_12695 6181578bd80372d23f1add6f7ebf1188 606 PRINTS PR00742 Glycosyl hydrolase family 35 signature 41 59 2.0E-50 T 14-10-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 MB46_12695 6181578bd80372d23f1add6f7ebf1188 606 PRINTS PR00742 Glycosyl hydrolase family 35 signature 538 554 2.0E-50 T 14-10-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 MB46_12695 6181578bd80372d23f1add6f7ebf1188 606 PRINTS PR00742 Glycosyl hydrolase family 35 signature 300 316 2.0E-50 T 14-10-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 MB46_12695 6181578bd80372d23f1add6f7ebf1188 606 PRINTS PR00742 Glycosyl hydrolase family 35 signature 97 116 2.0E-50 T 14-10-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 MB46_12695 6181578bd80372d23f1add6f7ebf1188 606 PRINTS PR00742 Glycosyl hydrolase family 35 signature 152 167 2.0E-50 T 14-10-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 MB46_12695 6181578bd80372d23f1add6f7ebf1188 606 PRINTS PR00742 Glycosyl hydrolase family 35 signature 238 253 2.0E-50 T 14-10-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 MB46_12695 6181578bd80372d23f1add6f7ebf1188 606 PRINTS PR00742 Glycosyl hydrolase family 35 signature 20 37 2.0E-50 T 14-10-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 MB46_12695 6181578bd80372d23f1add6f7ebf1188 606 PRINTS PR00742 Glycosyl hydrolase family 35 signature 389 403 2.0E-50 T 14-10-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 MB46_12695 6181578bd80372d23f1add6f7ebf1188 606 PRINTS PR00742 Glycosyl hydrolase family 35 signature 274 289 2.0E-50 T 14-10-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 MB46_14390 37406c8c6422840ae7e1a9aa906efeb3 306 Pfam PF00781 Diacylglycerol kinase catalytic domain 15 132 2.1E-15 T 14-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 MB46_14390 37406c8c6422840ae7e1a9aa906efeb3 306 SUPERFAMILY SSF111331 15 301 4.14E-61 T 14-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily MB46_14390 37406c8c6422840ae7e1a9aa906efeb3 306 Gene3D G3DSA:2.60.200.40 134 292 1.1E-36 T 14-10-2018 MB46_14390 37406c8c6422840ae7e1a9aa906efeb3 306 Gene3D G3DSA:3.40.50.10330 9 133 4.1E-21 T 14-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 MB46_17185 e02df707daa02e3a44e961bec89f886b 208 Gene3D G3DSA:3.40.50.2300 7 141 3.2E-31 T 14-10-2018 MB46_17185 e02df707daa02e3a44e961bec89f886b 208 Gene3D G3DSA:1.10.10.10 142 208 1.5E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_17185 e02df707daa02e3a44e961bec89f886b 208 SUPERFAMILY SSF52172 9 137 7.54E-28 T 14-10-2018 IPR011006 CheY-like superfamily MB46_17185 e02df707daa02e3a44e961bec89f886b 208 SUPERFAMILY SSF46894 134 208 9.52E-16 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MB46_17185 e02df707daa02e3a44e961bec89f886b 208 SMART SM00448 10 122 2.7E-22 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MB46_17185 e02df707daa02e3a44e961bec89f886b 208 Pfam PF00196 Bacterial regulatory proteins, luxR family 147 201 1.4E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_17185 e02df707daa02e3a44e961bec89f886b 208 SMART SM00421 145 202 3.7E-10 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_17185 e02df707daa02e3a44e961bec89f886b 208 Pfam PF00072 Response regulator receiver domain 13 121 1.5E-20 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MB46_14255 be40b1334af259b329c5d2f600599363 591 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 442 574 4.1E-10 T 14-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MB46_14255 be40b1334af259b329c5d2f600599363 591 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 493 509 - T 14-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MB46_14255 be40b1334af259b329c5d2f600599363 591 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 116 181 1.9E-19 T 14-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MB46_14255 be40b1334af259b329c5d2f600599363 591 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 365 425 4.1E-13 T 14-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MB46_14255 be40b1334af259b329c5d2f600599363 591 PRINTS PR00397 Sirohaem Fe-binding site signature 442 460 1.1E-8 T 14-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MB46_14255 be40b1334af259b329c5d2f600599363 591 PRINTS PR00397 Sirohaem Fe-binding site signature 493 511 1.1E-8 T 14-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MB46_14255 be40b1334af259b329c5d2f600599363 591 SUPERFAMILY SSF55124 40 189 1.14E-38 T 14-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MB46_14255 be40b1334af259b329c5d2f600599363 591 SUPERFAMILY SSF56014 441 590 4.84E-31 T 14-10-2018 MB46_14255 be40b1334af259b329c5d2f600599363 591 Gene3D G3DSA:3.30.413.10 439 591 2.5E-34 T 14-10-2018 MB46_14255 be40b1334af259b329c5d2f600599363 591 Gene3D G3DSA:3.30.413.10 182 360 4.2E-122 T 14-10-2018 MB46_14255 be40b1334af259b329c5d2f600599363 591 Gene3D G3DSA:3.90.480.20 52 425 4.2E-122 T 14-10-2018 MB46_14255 be40b1334af259b329c5d2f600599363 591 SUPERFAMILY SSF55124 322 453 1.96E-18 T 14-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MB46_14255 be40b1334af259b329c5d2f600599363 591 SUPERFAMILY SSF56014 190 349 2.75E-43 T 14-10-2018 MB46_14255 be40b1334af259b329c5d2f600599363 591 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 190 345 1.9E-35 T 14-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MB46_04945 c408ec96b08f3eea16f5c8704596e598 450 Pfam PF13527 Acetyltransferase (GNAT) domain 83 165 7.4E-17 T 14-10-2018 MB46_04945 c408ec96b08f3eea16f5c8704596e598 450 Hamap MF_01812 N-acetyltransferase Eis [eis]. 36 450 28.762 T 14-10-2018 IPR022902 N-acetyltransferase Eis MB46_04945 c408ec96b08f3eea16f5c8704596e598 450 Gene3D G3DSA:3.40.630.30 169 331 1.2E-25 T 14-10-2018 MB46_04945 c408ec96b08f3eea16f5c8704596e598 450 SUPERFAMILY SSF55729 82 338 1.53E-37 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase MB46_04945 c408ec96b08f3eea16f5c8704596e598 450 Gene3D G3DSA:3.40.630.30 30 168 8.7E-26 T 14-10-2018 MB46_04945 c408ec96b08f3eea16f5c8704596e598 450 Gene3D G3DSA:3.30.1050.10 337 440 4.9E-30 T 14-10-2018 IPR036527 SCP2 sterol-binding domain superfamily MB46_04945 c408ec96b08f3eea16f5c8704596e598 450 SUPERFAMILY SSF55718 339 450 1.45E-19 T 14-10-2018 IPR036527 SCP2 sterol-binding domain superfamily MB46_04945 c408ec96b08f3eea16f5c8704596e598 450 Pfam PF13530 Sterol carrier protein domain 246 446 1.2E-44 T 14-10-2018 IPR025559 Enhanced intracellular survival protein domain MB46_04590 0b33de0d6a19e96721fa78ac5b468a14 615 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 18 187 7.3E-21 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MB46_04590 0b33de0d6a19e96721fa78ac5b468a14 615 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 54 69 - T 14-10-2018 IPR031157 Tr-type G domain, conserved site MB46_04590 0b33de0d6a19e96721fa78ac5b468a14 615 Hamap MF_00071 Elongation factor 4 [lepA]. 1 611 277.444 T 14-10-2018 IPR006297 Elongation factor 4 GO:0005525 MB46_04590 0b33de0d6a19e96721fa78ac5b468a14 615 SUPERFAMILY SSF52540 11 214 8.3E-58 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_04590 0b33de0d6a19e96721fa78ac5b468a14 615 SMART SM00838 411 496 0.001 T 14-10-2018 IPR000640 Elongation factor EFG, domain V-like MB46_04590 0b33de0d6a19e96721fa78ac5b468a14 615 SUPERFAMILY SSF54980 303 381 1.29E-17 T 14-10-2018 IPR035647 EF-G domain III/V-like MB46_04590 0b33de0d6a19e96721fa78ac5b468a14 615 Pfam PF06421 GTP-binding protein LepA C-terminus 499 603 2.1E-47 T 14-10-2018 IPR013842 GTP-binding protein LepA, C-terminal MB46_04590 0b33de0d6a19e96721fa78ac5b468a14 615 TIGRFAM TIGR01393 lepA: elongation factor 4 16 604 2.6E-286 T 14-10-2018 IPR006297 Elongation factor 4 GO:0005525 MB46_04590 0b33de0d6a19e96721fa78ac5b468a14 615 SUPERFAMILY SSF50447 176 298 6.31E-26 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily MB46_04590 0b33de0d6a19e96721fa78ac5b468a14 615 Gene3D G3DSA:3.30.70.3380 379 488 1.6E-35 T 14-10-2018 MB46_04590 0b33de0d6a19e96721fa78ac5b468a14 615 Pfam PF00679 Elongation factor G C-terminus 409 495 3.9E-20 T 14-10-2018 IPR000640 Elongation factor EFG, domain V-like MB46_04590 0b33de0d6a19e96721fa78ac5b468a14 615 Gene3D G3DSA:3.30.70.2570 490 564 8.5E-32 T 14-10-2018 IPR038363 LepA, C-terminal domain superfamily MB46_04590 0b33de0d6a19e96721fa78ac5b468a14 615 SUPERFAMILY SSF54980 409 504 5.28E-22 T 14-10-2018 IPR035647 EF-G domain III/V-like MB46_04590 0b33de0d6a19e96721fa78ac5b468a14 615 Gene3D G3DSA:3.30.70.870 297 378 8.0E-32 T 14-10-2018 MB46_04590 0b33de0d6a19e96721fa78ac5b468a14 615 Pfam PF00009 Elongation factor Tu GTP binding domain 16 192 1.6E-52 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MB46_04590 0b33de0d6a19e96721fa78ac5b468a14 615 Gene3D G3DSA:3.40.50.300 12 196 1.1E-70 T 14-10-2018 MB46_04590 0b33de0d6a19e96721fa78ac5b468a14 615 PRINTS PR00315 GTP-binding elongation factor signature 61 69 4.8E-14 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MB46_04590 0b33de0d6a19e96721fa78ac5b468a14 615 PRINTS PR00315 GTP-binding elongation factor signature 137 146 4.8E-14 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MB46_04590 0b33de0d6a19e96721fa78ac5b468a14 615 PRINTS PR00315 GTP-binding elongation factor signature 18 31 4.8E-14 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MB46_04590 0b33de0d6a19e96721fa78ac5b468a14 615 PRINTS PR00315 GTP-binding elongation factor signature 101 112 4.8E-14 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MB46_04590 0b33de0d6a19e96721fa78ac5b468a14 615 PRINTS PR00315 GTP-binding elongation factor signature 85 95 4.8E-14 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MB46_04590 0b33de0d6a19e96721fa78ac5b468a14 615 Gene3D G3DSA:2.40.30.10 197 296 3.5E-32 T 14-10-2018 MB46_11135 2a1dcc89fb492fd0b0f6a2d6143bfbcb 475 Pfam PF08125 Mannitol dehydrogenase C-terminal domain 221 449 2.9E-54 T 14-10-2018 IPR013118 Mannitol dehydrogenase, C-terminal GO:0016491|GO:0050662|GO:0055114 MB46_11135 2a1dcc89fb492fd0b0f6a2d6143bfbcb 475 PRINTS PR00084 Mannitol dehydrogenase signature 184 197 6.0E-15 T 14-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 MB46_11135 2a1dcc89fb492fd0b0f6a2d6143bfbcb 475 PRINTS PR00084 Mannitol dehydrogenase signature 223 236 6.0E-15 T 14-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 MB46_11135 2a1dcc89fb492fd0b0f6a2d6143bfbcb 475 PRINTS PR00084 Mannitol dehydrogenase signature 20 30 6.0E-15 T 14-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 MB46_11135 2a1dcc89fb492fd0b0f6a2d6143bfbcb 475 PRINTS PR00084 Mannitol dehydrogenase signature 253 268 6.0E-15 T 14-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 MB46_11135 2a1dcc89fb492fd0b0f6a2d6143bfbcb 475 Gene3D G3DSA:1.10.1040.10 287 475 2.6E-47 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MB46_11135 2a1dcc89fb492fd0b0f6a2d6143bfbcb 475 Pfam PF01232 Mannitol dehydrogenase Rossmann domain 19 193 2.3E-27 T 14-10-2018 IPR013131 Mannitol dehydrogenase, N-terminal GO:0016491|GO:0055114 MB46_11135 2a1dcc89fb492fd0b0f6a2d6143bfbcb 475 SUPERFAMILY SSF51735 10 287 7.68E-66 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_11135 2a1dcc89fb492fd0b0f6a2d6143bfbcb 475 Gene3D G3DSA:3.40.50.720 2 286 6.0E-84 T 14-10-2018 MB46_11135 2a1dcc89fb492fd0b0f6a2d6143bfbcb 475 SUPERFAMILY SSF48179 289 468 1.22E-36 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MB46_02210 b7d282e460fb47b1934abe2c47a206ec 334 Gene3D G3DSA:3.40.630.30 139 297 1.6E-50 T 14-10-2018 MB46_02210 b7d282e460fb47b1934abe2c47a206ec 334 SUPERFAMILY SSF55729 1 156 3.84E-16 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase MB46_02210 b7d282e460fb47b1934abe2c47a206ec 334 Pfam PF02388 FemAB family 20 113 5.1E-7 T 14-10-2018 IPR003447 FemABX peptidyl transferase GO:0016755|GO:0044038 MB46_02210 b7d282e460fb47b1934abe2c47a206ec 334 SUPERFAMILY SSF55729 146 312 1.85E-31 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase MB46_02210 b7d282e460fb47b1934abe2c47a206ec 334 Gene3D G3DSA:3.40.630.30 19 309 1.6E-50 T 14-10-2018 MB46_02210 b7d282e460fb47b1934abe2c47a206ec 334 Pfam PF13480 Acetyltransferase (GNAT) domain 156 279 3.9E-13 T 14-10-2018 IPR038740 BioF2-like, acetyltransferase domain KEGG: 00780+2.3.1.47|MetaCyc: PWY-6519|MetaCyc: PWY-6578|MetaCyc: PWY-7147 MB46_12550 40b9373a5fe3bd92f1a8a395b56167c8 638 PRINTS PR00315 GTP-binding elongation factor signature 139 148 7.4E-16 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MB46_12550 40b9373a5fe3bd92f1a8a395b56167c8 638 PRINTS PR00315 GTP-binding elongation factor signature 87 97 7.4E-16 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MB46_12550 40b9373a5fe3bd92f1a8a395b56167c8 638 PRINTS PR00315 GTP-binding elongation factor signature 103 114 7.4E-16 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MB46_12550 40b9373a5fe3bd92f1a8a395b56167c8 638 PRINTS PR00315 GTP-binding elongation factor signature 16 29 7.4E-16 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MB46_12550 40b9373a5fe3bd92f1a8a395b56167c8 638 PRINTS PR00315 GTP-binding elongation factor signature 60 68 7.4E-16 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MB46_12550 40b9373a5fe3bd92f1a8a395b56167c8 638 SUPERFAMILY SSF54980 430 544 6.23E-27 T 14-10-2018 IPR035647 EF-G domain III/V-like MB46_12550 40b9373a5fe3bd92f1a8a395b56167c8 638 SUPERFAMILY SSF54980 334 419 1.44E-10 T 14-10-2018 IPR035647 EF-G domain III/V-like MB46_12550 40b9373a5fe3bd92f1a8a395b56167c8 638 SUPERFAMILY SSF50447 212 331 3.79E-30 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily MB46_12550 40b9373a5fe3bd92f1a8a395b56167c8 638 Gene3D G3DSA:2.40.50.250 514 629 2.0E-118 T 14-10-2018 MB46_12550 40b9373a5fe3bd92f1a8a395b56167c8 638 SUPERFAMILY SSF52540 11 201 3.02E-49 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_12550 40b9373a5fe3bd92f1a8a395b56167c8 638 Pfam PF03144 Elongation factor Tu domain 2 250 320 5.6E-12 T 14-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 MB46_12550 40b9373a5fe3bd92f1a8a395b56167c8 638 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 53 68 - T 14-10-2018 IPR031157 Tr-type G domain, conserved site MB46_12550 40b9373a5fe3bd92f1a8a395b56167c8 638 Pfam PF00009 Elongation factor Tu GTP binding domain 13 226 7.4E-50 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MB46_12550 40b9373a5fe3bd92f1a8a395b56167c8 638 Gene3D G3DSA:3.30.70.240 421 513 2.0E-118 T 14-10-2018 MB46_12550 40b9373a5fe3bd92f1a8a395b56167c8 638 Gene3D G3DSA:3.40.50.300 11 229 1.8E-55 T 14-10-2018 MB46_12550 40b9373a5fe3bd92f1a8a395b56167c8 638 Gene3D G3DSA:3.30.70.870 338 621 2.0E-118 T 14-10-2018 MB46_12550 40b9373a5fe3bd92f1a8a395b56167c8 638 SMART SM00838 427 515 0.0064 T 14-10-2018 IPR000640 Elongation factor EFG, domain V-like MB46_12550 40b9373a5fe3bd92f1a8a395b56167c8 638 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 14 629 2.0E-267 T 14-10-2018 IPR006298 GTP-binding protein TypA GO:0005525 MB46_12550 40b9373a5fe3bd92f1a8a395b56167c8 638 Pfam PF00679 Elongation factor G C-terminus 428 510 2.4E-21 T 14-10-2018 IPR000640 Elongation factor EFG, domain V-like MB46_12550 40b9373a5fe3bd92f1a8a395b56167c8 638 Gene3D G3DSA:2.40.30.10 231 330 3.7E-28 T 14-10-2018 MB46_12550 40b9373a5fe3bd92f1a8a395b56167c8 638 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 15 161 3.8E-23 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MB46_18760 5c91e539c02dd308d9ea150f1eacf5e5 228 Pfam PF04131 Putative N-acetylmannosamine-6-phosphate epimerase 33 226 8.8E-55 T 14-10-2018 IPR007260 Putative N-acetylmannosamine-6-phosphate epimerase GO:0006051|GO:0047465 KEGG: 00520+5.1.3.9 MB46_18760 5c91e539c02dd308d9ea150f1eacf5e5 228 SUPERFAMILY SSF51366 11 225 3.77E-52 T 14-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 MB46_18760 5c91e539c02dd308d9ea150f1eacf5e5 228 Gene3D G3DSA:3.20.20.70 3 226 1.3E-83 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MB46_18760 5c91e539c02dd308d9ea150f1eacf5e5 228 Hamap MF_01235 Putative N-acetylmannosamine-6-phosphate 2-epimerase [nanE]. 9 227 34.17 T 14-10-2018 IPR007260 Putative N-acetylmannosamine-6-phosphate epimerase GO:0006051|GO:0047465 KEGG: 00520+5.1.3.9 MB46_10655 7907ac5e510dc92383bd6c98c0bfbe9a 388 SUPERFAMILY SSF56300 1 268 6.65E-51 T 14-10-2018 MB46_10655 7907ac5e510dc92383bd6c98c0bfbe9a 388 Gene3D G3DSA:3.60.21.10 1 270 6.2E-80 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like MB46_10655 7907ac5e510dc92383bd6c98c0bfbe9a 388 Pfam PF00149 Calcineurin-like phosphoesterase 1 137 5.4E-14 T 14-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 MB46_10655 7907ac5e510dc92383bd6c98c0bfbe9a 388 TIGRFAM TIGR00619 sbcd: exonuclease SbcCD, D subunit 1 248 9.9E-52 T 14-10-2018 IPR004593 Nuclease SbcCD subunit D GO:0004519|GO:0006259|GO:0008408 MB46_15365 6c121832e2cd8ab34b23d803c93c46ba 356 Pfam PF12826 Helix-hairpin-helix motif 295 341 5.7E-7 T 14-10-2018 MB46_15365 6c121832e2cd8ab34b23d803c93c46ba 356 Gene3D G3DSA:1.10.150.20 289 351 5.2E-19 T 14-10-2018 MB46_15365 6c121832e2cd8ab34b23d803c93c46ba 356 SUPERFAMILY SSF143597 17 140 3.27E-26 T 14-10-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily MB46_15365 6c121832e2cd8ab34b23d803c93c46ba 356 Gene3D G3DSA:1.20.1260.110 144 288 2.2E-40 T 14-10-2018 IPR038331 DisA, linker domain superfamily MB46_15365 6c121832e2cd8ab34b23d803c93c46ba 356 Gene3D G3DSA:3.40.1700.10 6 141 2.8E-56 T 14-10-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily MB46_15365 6c121832e2cd8ab34b23d803c93c46ba 356 Hamap MF_01438 DNA integrity scanning protein DisA [disA]. 3 353 40.811 T 14-10-2018 IPR023763 DNA integrity scanning protein, DisA MB46_15365 6c121832e2cd8ab34b23d803c93c46ba 356 SUPERFAMILY SSF47781 259 345 1.71E-11 T 14-10-2018 IPR010994 RuvA domain 2-like MB46_15365 6c121832e2cd8ab34b23d803c93c46ba 356 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 24 136 2.0E-23 T 14-10-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal MB46_15365 6c121832e2cd8ab34b23d803c93c46ba 356 Pfam PF10635 DisA bacterial checkpoint controller linker region 141 278 4.4E-45 T 14-10-2018 IPR018906 DNA integrity scanning, DisA, linker region MB46_14300 4d47405568d8099657995e92e8c20870 440 Pfam PF01494 FAD binding domain 2 316 8.3E-13 T 14-10-2018 IPR002938 FAD-binding domain GO:0071949 MB46_14300 4d47405568d8099657995e92e8c20870 440 Gene3D G3DSA:3.50.50.60 2 402 3.3E-86 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_14300 4d47405568d8099657995e92e8c20870 440 SUPERFAMILY SSF51905 2 382 4.3E-42 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_14300 4d47405568d8099657995e92e8c20870 440 TIGRFAM TIGR02032 GG-red-SF: geranylgeranyl reductase family 4 325 9.5E-73 T 14-10-2018 IPR011777 Geranylgeranyl reductase family GO:0016628|GO:0055114 MB46_14300 4d47405568d8099657995e92e8c20870 440 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 305 321 8.6E-10 T 14-10-2018 MB46_14300 4d47405568d8099657995e92e8c20870 440 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 8.6E-10 T 14-10-2018 MB46_14300 4d47405568d8099657995e92e8c20870 440 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 156 171 8.6E-10 T 14-10-2018 MB46_14300 4d47405568d8099657995e92e8c20870 440 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 290 305 8.6E-10 T 14-10-2018 MB46_04060 c09c179afd791cf4f39db013d6dbf601 354 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 65 350 4.9E-86 T 14-10-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 MB46_04060 c09c179afd791cf4f39db013d6dbf601 354 SUPERFAMILY SSF46589 28 112 4.34E-11 T 14-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 MB46_04060 c09c179afd791cf4f39db013d6dbf601 354 Pfam PF01409 tRNA synthetases class II core domain (F) 108 350 6.9E-98 T 14-10-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 MB46_04060 c09c179afd791cf4f39db013d6dbf601 354 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 24 350 42.78 T 14-10-2018 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 MB46_04060 c09c179afd791cf4f39db013d6dbf601 354 Gene3D G3DSA:3.30.930.10 23 352 3.7E-104 T 14-10-2018 MB46_04060 c09c179afd791cf4f39db013d6dbf601 354 SUPERFAMILY SSF55681 108 351 1.09E-76 T 14-10-2018 MB46_04060 c09c179afd791cf4f39db013d6dbf601 354 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 36 101 1.1E-11 T 14-10-2018 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 MB46_12535 3feacbb29881563657432ee5213ea3c5 309 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 27 63 1.9E-7 T 14-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain MB46_12535 3feacbb29881563657432ee5213ea3c5 309 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 120 308 3.0E-30 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_12535 3feacbb29881563657432ee5213ea3c5 309 SUPERFAMILY SSF161098 98 289 2.49E-23 T 14-10-2018 IPR035906 MetI-like superfamily MB46_12535 3feacbb29881563657432ee5213ea3c5 309 Gene3D G3DSA:1.10.3720.10 91 308 5.4E-23 T 14-10-2018 IPR035906 MetI-like superfamily MB46_16475 2d26ecd161e02638192518a954abc692 582 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 385 530 9.9E-39 T 14-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 MB46_16475 2d26ecd161e02638192518a954abc692 582 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 422 441 - T 14-10-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 MB46_16475 2d26ecd161e02638192518a954abc692 582 Gene3D G3DSA:3.40.50.1220 184 336 5.2E-40 T 14-10-2018 MB46_16475 2d26ecd161e02638192518a954abc692 582 SUPERFAMILY SSF52518 6 183 4.98E-40 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold MB46_16475 2d26ecd161e02638192518a954abc692 582 Gene3D G3DSA:3.40.50.970 2 180 8.3E-52 T 14-10-2018 MB46_16475 2d26ecd161e02638192518a954abc692 582 SUPERFAMILY SSF52467 188 347 1.85E-36 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily MB46_16475 2d26ecd161e02638192518a954abc692 582 SUPERFAMILY SSF52518 362 561 2.09E-59 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold MB46_16475 2d26ecd161e02638192518a954abc692 582 Gene3D G3DSA:3.40.50.970 354 578 6.1E-62 T 14-10-2018 MB46_16475 2d26ecd161e02638192518a954abc692 582 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 5 174 2.5E-36 T 14-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 MB46_16475 2d26ecd161e02638192518a954abc692 582 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 195 322 3.6E-27 T 14-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 MB46_05925 7a4959bdaed802f718512319bf218b9e 226 SUPERFAMILY SSF48498 106 225 4.36E-8 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily MB46_05925 7a4959bdaed802f718512319bf218b9e 226 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 62 85 6.5E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MB46_05925 7a4959bdaed802f718512319bf218b9e 226 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 42 55 6.5E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MB46_05925 7a4959bdaed802f718512319bf218b9e 226 SUPERFAMILY SSF46689 36 98 1.85E-12 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MB46_05925 7a4959bdaed802f718512319bf218b9e 226 Gene3D G3DSA:1.10.357.10 26 226 9.2E-35 T 14-10-2018 MB46_05925 7a4959bdaed802f718512319bf218b9e 226 Pfam PF00440 Bacterial regulatory proteins, tetR family 43 86 4.5E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MB46_15020 dcbe3d5b08fc95141df4dd9b8113a426 284 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 109 265 2.6E-22 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_15020 dcbe3d5b08fc95141df4dd9b8113a426 284 Gene3D G3DSA:1.10.3720.10 86 272 3.3E-32 T 14-10-2018 IPR035906 MetI-like superfamily MB46_15020 dcbe3d5b08fc95141df4dd9b8113a426 284 SUPERFAMILY SSF161098 87 268 9.29E-37 T 14-10-2018 IPR035906 MetI-like superfamily MB46_17635 22d44dd729692dbe424688201630d6ea 307 SMART SM01130 2 295 3.2E-65 T 14-10-2018 IPR002220 DapA-like GO:0016829 MB46_17635 22d44dd729692dbe424688201630d6ea 307 Gene3D G3DSA:3.20.20.70 2 303 5.6E-78 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MB46_17635 22d44dd729692dbe424688201630d6ea 307 Pfam PF00701 Dihydrodipicolinate synthetase family 2 293 3.7E-51 T 14-10-2018 IPR002220 DapA-like GO:0016829 MB46_17635 22d44dd729692dbe424688201630d6ea 307 Hamap MF_00694 Probable 5-dehydro-4-deoxyglucarate dehydratase. 2 296 41.932 T 14-10-2018 IPR017655 5-dehydro-4-deoxyglucarate dehydratase GO:0016052|GO:0047448 KEGG: 00053+4.2.1.41|MetaCyc: PWY-6486|MetaCyc: PWY-6497|MetaCyc: PWY-6499|MetaCyc: PWY-6501 MB46_17635 22d44dd729692dbe424688201630d6ea 307 PIRSF PIRSF001365 1 302 1.3E-49 T 14-10-2018 IPR002220 DapA-like GO:0016829 MB46_17635 22d44dd729692dbe424688201630d6ea 307 SUPERFAMILY SSF51569 2 293 2.2E-61 T 14-10-2018 MB46_01755 0f01434b962c18c173c9c8a1f783c2ca 422 Pfam PF02653 Branched-chain amino acid transport system / permease component 42 378 9.0E-38 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 MB46_10535 61d1114789a4d7a7f5b07532edf87289 254 SUPERFAMILY SSF56784 18 207 5.21E-9 T 14-10-2018 IPR036412 HAD-like superfamily MB46_10535 61d1114789a4d7a7f5b07532edf87289 254 Gene3D G3DSA:3.40.50.1000 96 231 2.3E-6 T 14-10-2018 IPR023214 HAD superfamily MB46_09185 991d8687b667bf5394464d8f825d2df6 283 Gene3D G3DSA:3.40.50.1820 4 282 7.5E-64 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_09185 991d8687b667bf5394464d8f825d2df6 283 Pfam PF12146 Serine aminopeptidase, S33 60 264 1.0E-15 T 14-10-2018 IPR022742 Serine aminopeptidase, S33 MB46_09185 991d8687b667bf5394464d8f825d2df6 283 PRINTS PR00111 Alpha/beta hydrolase fold signature 227 241 1.1E-8 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MB46_09185 991d8687b667bf5394464d8f825d2df6 283 PRINTS PR00111 Alpha/beta hydrolase fold signature 119 132 1.1E-8 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MB46_09185 991d8687b667bf5394464d8f825d2df6 283 PRINTS PR00111 Alpha/beta hydrolase fold signature 62 77 1.1E-8 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MB46_09185 991d8687b667bf5394464d8f825d2df6 283 PRINTS PR00111 Alpha/beta hydrolase fold signature 105 118 1.1E-8 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MB46_09185 991d8687b667bf5394464d8f825d2df6 283 SUPERFAMILY SSF53474 15 282 4.82E-53 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_15935 99b7cfb3c4c5266918ae9250418dc966 331 Pfam PF13343 Bacterial extracellular solute-binding protein 69 314 1.1E-25 T 14-10-2018 MB46_15935 99b7cfb3c4c5266918ae9250418dc966 331 Gene3D G3DSA:3.40.190.10 118 321 1.1E-86 T 14-10-2018 MB46_15935 99b7cfb3c4c5266918ae9250418dc966 331 SUPERFAMILY SSF53850 17 312 8.15E-55 T 14-10-2018 MB46_15935 99b7cfb3c4c5266918ae9250418dc966 331 Gene3D G3DSA:3.40.190.10 39 298 1.1E-86 T 14-10-2018 MB46_01915 1a4adc9ee780c803bff953aa70ed46a2 263 Gene3D G3DSA:3.10.20.30 27 133 1.3E-34 T 14-10-2018 IPR012675 Beta-grasp domain superfamily MB46_01915 1a4adc9ee780c803bff953aa70ed46a2 263 SUPERFAMILY SSF54292 30 133 1.41E-27 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 MB46_01915 1a4adc9ee780c803bff953aa70ed46a2 263 Pfam PF13183 4Fe-4S dicluster domain 173 245 7.4E-12 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MB46_01915 1a4adc9ee780c803bff953aa70ed46a2 263 SUPERFAMILY SSF46548 134 260 4.19E-32 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 MB46_01915 1a4adc9ee780c803bff953aa70ed46a2 263 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 33 138 1.4E-35 T 14-10-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 MB46_01915 1a4adc9ee780c803bff953aa70ed46a2 263 Gene3D G3DSA:1.10.1060.10 134 263 4.5E-45 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 MB46_01915 1a4adc9ee780c803bff953aa70ed46a2 263 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 175 186 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MB46_01915 1a4adc9ee780c803bff953aa70ed46a2 263 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 36 255 1.1E-77 T 14-10-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 MB46_19660 9312a80cf3fe3b997582812f7da57208 58 Gene3D G3DSA:1.10.1470.10 4 58 1.2E-5 T 14-10-2018 IPR036629 YjbJ superfamily MB46_19660 9312a80cf3fe3b997582812f7da57208 58 Pfam PF05532 CsbD-like 5 57 5.3E-17 T 14-10-2018 IPR008462 CsbD-like domain MB46_19660 9312a80cf3fe3b997582812f7da57208 58 SUPERFAMILY SSF69047 5 57 3.92E-8 T 14-10-2018 IPR036629 YjbJ superfamily MB46_05985 1b946319b05998fad4df9f8dfb5a70ff 300 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 291 4.8E-23 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_05985 1b946319b05998fad4df9f8dfb5a70ff 300 SUPERFAMILY SSF161098 30 296 4.58E-70 T 14-10-2018 IPR035906 MetI-like superfamily MB46_05985 1b946319b05998fad4df9f8dfb5a70ff 300 Gene3D G3DSA:1.10.3720.10 19 290 1.8E-68 T 14-10-2018 IPR035906 MetI-like superfamily MB46_10770 f9ad498e4e1418499eed94a7f64e6ed6 260 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 11 224 2.9E-23 T 14-10-2018 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 MB46_10770 f9ad498e4e1418499eed94a7f64e6ed6 260 Hamap MF_01241 Glucosamine-6-phosphate deaminase [nagB]. 1 241 39.812 T 14-10-2018 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70171 MB46_10770 f9ad498e4e1418499eed94a7f64e6ed6 260 SUPERFAMILY SSF100950 1 247 2.33E-90 T 14-10-2018 IPR037171 NagB/RpiA transferase-like MB46_10770 f9ad498e4e1418499eed94a7f64e6ed6 260 ProSitePatterns PS01161 Glucosamine/galactosamine-6-phosphate isomerases signature. 120 138 - T 14-10-2018 IPR018321 Glucosamine-6-phosphate isomerase, conserved site GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70171 MB46_10770 f9ad498e4e1418499eed94a7f64e6ed6 260 TIGRFAM TIGR00502 nagB: glucosamine-6-phosphate deaminase 1 244 2.1E-80 T 14-10-2018 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70171 MB46_10770 f9ad498e4e1418499eed94a7f64e6ed6 260 Gene3D G3DSA:3.40.50.1360 1 254 1.0E-93 T 14-10-2018 MB46_05270 05873d5bc0ed6eb9eb2d117a8025e7ab 336 Pfam PF03601 Conserved hypothetical protein 698 6 316 1.3E-60 T 14-10-2018 IPR018383 Uncharacterised protein family UPF0324, prokaryote GO:0016021 MB46_02770 ea4233543a7182352a64d44c6d2ae1c2 506 Gene3D G3DSA:1.10.10.1100 452 504 4.8E-11 T 14-10-2018 MB46_02770 ea4233543a7182352a64d44c6d2ae1c2 506 Pfam PF04324 BFD-like [2Fe-2S] binding domain 452 500 3.8E-11 T 14-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain MB46_02770 ea4233543a7182352a64d44c6d2ae1c2 506 Gene3D G3DSA:3.50.50.60 118 257 2.5E-64 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_02770 ea4233543a7182352a64d44c6d2ae1c2 506 Gene3D G3DSA:3.50.50.60 8 301 2.5E-64 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_02770 ea4233543a7182352a64d44c6d2ae1c2 506 SUPERFAMILY SSF51905 157 303 3.88E-22 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_02770 ea4233543a7182352a64d44c6d2ae1c2 506 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 298 1.3E-38 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MB46_02770 ea4233543a7182352a64d44c6d2ae1c2 506 SUPERFAMILY SSF51905 6 202 6.35E-29 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_02770 ea4233543a7182352a64d44c6d2ae1c2 506 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 250 266 8.2E-13 T 14-10-2018 MB46_02770 ea4233543a7182352a64d44c6d2ae1c2 506 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 8.2E-13 T 14-10-2018 MB46_02770 ea4233543a7182352a64d44c6d2ae1c2 506 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 276 298 8.2E-13 T 14-10-2018 MB46_02770 ea4233543a7182352a64d44c6d2ae1c2 506 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 105 123 8.2E-13 T 14-10-2018 MB46_02770 ea4233543a7182352a64d44c6d2ae1c2 506 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 159 177 8.2E-13 T 14-10-2018 MB46_10300 d4797efafe4fc0c7f8b9a9f310d36a9b 473 Pfam PF02195 ParB-like nuclease domain 7 86 2.0E-13 T 14-10-2018 IPR003115 ParB/Sulfiredoxin MB46_10300 d4797efafe4fc0c7f8b9a9f310d36a9b 473 Gene3D G3DSA:1.10.10.2830 89 191 2.6E-9 T 14-10-2018 MB46_10300 d4797efafe4fc0c7f8b9a9f310d36a9b 473 Gene3D G3DSA:3.90.1530.30 20 81 1.3E-8 T 14-10-2018 MB46_10300 d4797efafe4fc0c7f8b9a9f310d36a9b 473 SUPERFAMILY SSF110849 6 83 2.79E-13 T 14-10-2018 IPR036086 ParB/Sulfiredoxin superfamily MB46_10300 d4797efafe4fc0c7f8b9a9f310d36a9b 473 SUPERFAMILY SSF109709 104 184 4.58E-8 T 14-10-2018 MB46_10300 d4797efafe4fc0c7f8b9a9f310d36a9b 473 SMART SM00470 6 98 1.7E-9 T 14-10-2018 IPR003115 ParB/Sulfiredoxin MB46_04165 49f84372029f752f315716308e731396 401 Hamap MF_00005 Argininosuccinate synthase [argG]. 2 396 52.257 T 14-10-2018 IPR023434 Argininosuccinate synthase, type 1 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MB46_04165 49f84372029f752f315716308e731396 401 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 8 16 - T 14-10-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MB46_04165 49f84372029f752f315716308e731396 401 Gene3D G3DSA:3.40.50.620 5 172 3.1E-138 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MB46_04165 49f84372029f752f315716308e731396 401 SUPERFAMILY SSF69864 171 396 1.96E-86 T 14-10-2018 MB46_04165 49f84372029f752f315716308e731396 401 SUPERFAMILY SSF52402 3 165 4.19E-42 T 14-10-2018 MB46_04165 49f84372029f752f315716308e731396 401 TIGRFAM TIGR00032 argG: argininosuccinate synthase 4 393 1.1E-147 T 14-10-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MB46_04165 49f84372029f752f315716308e731396 401 Gene3D G3DSA:3.90.1260.10 64 352 3.1E-138 T 14-10-2018 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MB46_04165 49f84372029f752f315716308e731396 401 Gene3D G3DSA:1.20.5.470 361 398 1.5E-19 T 14-10-2018 MB46_04165 49f84372029f752f315716308e731396 401 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 117 128 - T 14-10-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MB46_04165 49f84372029f752f315716308e731396 401 Pfam PF00764 Arginosuccinate synthase 6 391 1.7E-181 T 14-10-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MB46_12025 ae0543d59a550e38b8bf347bfe4b58b8 326 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 242 254 - T 14-10-2018 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 MB46_12025 ae0543d59a550e38b8bf347bfe4b58b8 326 PIRSF PIRSF001415 1 326 8.2E-142 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 MB46_12025 ae0543d59a550e38b8bf347bfe4b58b8 326 Gene3D G3DSA:3.20.20.70 1 326 4.8E-135 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MB46_12025 ae0543d59a550e38b8bf347bfe4b58b8 326 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 267 282 4.6E-56 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 MB46_12025 ae0543d59a550e38b8bf347bfe4b58b8 326 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 297 316 4.6E-56 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 MB46_12025 ae0543d59a550e38b8bf347bfe4b58b8 326 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 122 136 4.6E-56 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 MB46_12025 ae0543d59a550e38b8bf347bfe4b58b8 326 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 242 258 4.6E-56 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 MB46_12025 ae0543d59a550e38b8bf347bfe4b58b8 326 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 153 172 4.6E-56 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 MB46_12025 ae0543d59a550e38b8bf347bfe4b58b8 326 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 191 210 4.6E-56 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 MB46_12025 ae0543d59a550e38b8bf347bfe4b58b8 326 SUPERFAMILY SSF51569 3 325 1.26E-128 T 14-10-2018 MB46_12025 ae0543d59a550e38b8bf347bfe4b58b8 326 SMART SM01004 3 323 1.2E-207 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 MB46_12025 ae0543d59a550e38b8bf347bfe4b58b8 326 Pfam PF00490 Delta-aminolevulinic acid dehydratase 6 322 1.0E-136 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 MB46_11455 ccfb34f54ad7595677a6466665f386ff 290 TIGRFAM TIGR01207 rmlA: glucose-1-phosphate thymidylyltransferase 2 285 3.2E-143 T 14-10-2018 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|KEGG: 00525+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 MB46_11455 ccfb34f54ad7595677a6466665f386ff 290 Pfam PF00483 Nucleotidyl transferase 3 237 6.4E-67 T 14-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 MB46_11455 ccfb34f54ad7595677a6466665f386ff 290 SUPERFAMILY SSF53448 1 286 4.23E-86 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MB46_11455 ccfb34f54ad7595677a6466665f386ff 290 Gene3D G3DSA:3.90.550.10 1 289 6.9E-82 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MB46_14435 9c2cea7c977ed6e066c1c099efbe1739 110 Gene3D G3DSA:3.10.20.520 15 80 7.7E-31 T 14-10-2018 IPR038693 Phenylacetyl-CoA epoxidase, subunit B MB46_14435 9c2cea7c977ed6e066c1c099efbe1739 110 Pfam PF06243 Phenylacetic acid degradation B 21 106 4.5E-37 T 14-10-2018 IPR009359 Phenylacetic acid degradation B MB46_14435 9c2cea7c977ed6e066c1c099efbe1739 110 PIRSF PIRSF030200 8 110 9.3E-42 T 14-10-2018 IPR009359 Phenylacetic acid degradation B MB46_14435 9c2cea7c977ed6e066c1c099efbe1739 110 TIGRFAM TIGR02157 PA_CoA_Oxy2: phenylacetate-CoA oxygenase, PaaH subunit 21 109 6.5E-38 T 14-10-2018 IPR009359 Phenylacetic acid degradation B MB46_10000 97e5937eb07899a0c78fe2517866f038 481 Gene3D G3DSA:1.20.1740.10 22 473 8.2E-59 T 14-10-2018 MB46_10000 97e5937eb07899a0c78fe2517866f038 481 Pfam PF00324 Amino acid permease 32 473 3.6E-89 T 14-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 MB46_10000 97e5937eb07899a0c78fe2517866f038 481 PIRSF PIRSF006060 4 480 3.1E-66 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 MB46_17685 28538b54c58526657cf30ba87b3760d5 432 Gene3D G3DSA:3.40.190.10 152 426 3.4E-118 T 14-10-2018 MB46_17685 28538b54c58526657cf30ba87b3760d5 432 SUPERFAMILY SSF53850 24 427 6.4E-59 T 14-10-2018 MB46_17685 28538b54c58526657cf30ba87b3760d5 432 Gene3D G3DSA:3.40.190.10 44 377 3.4E-118 T 14-10-2018 MB46_17685 28538b54c58526657cf30ba87b3760d5 432 Pfam PF13416 Bacterial extracellular solute-binding protein 61 359 2.0E-25 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein MB46_18250 530aa1d35b1cdc06d7c333c39a7812a1 367 Gene3D G3DSA:3.30.360.10 143 367 7.1E-42 T 14-10-2018 MB46_18250 530aa1d35b1cdc06d7c333c39a7812a1 367 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 12 129 2.3E-23 T 14-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 MB46_18250 530aa1d35b1cdc06d7c333c39a7812a1 367 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 143 221 1.9E-7 T 14-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 MB46_18250 530aa1d35b1cdc06d7c333c39a7812a1 367 Gene3D G3DSA:3.40.50.720 4 142 5.7E-38 T 14-10-2018 MB46_18250 530aa1d35b1cdc06d7c333c39a7812a1 367 SUPERFAMILY SSF51735 11 164 4.66E-47 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_18250 530aa1d35b1cdc06d7c333c39a7812a1 367 SUPERFAMILY SSF55347 139 309 4.41E-30 T 14-10-2018 MB46_09625 725da2b1eb424d5710a5c9b8689eff75 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 8.2E-35 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 MB46_09625 725da2b1eb424d5710a5c9b8689eff75 112 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 14-10-2018 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 MB46_09625 725da2b1eb424d5710a5c9b8689eff75 112 Gene3D G3DSA:3.30.70.120 1 112 1.1E-38 T 14-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal MB46_09625 725da2b1eb424d5710a5c9b8689eff75 112 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 14-10-2018 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 MB46_09625 725da2b1eb424d5710a5c9b8689eff75 112 SMART SM00938 4 105 2.8E-50 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 MB46_09625 725da2b1eb424d5710a5c9b8689eff75 112 SUPERFAMILY SSF54913 1 112 1.65E-37 T 14-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta MB46_09625 725da2b1eb424d5710a5c9b8689eff75 112 PRINTS PR00340 P-II protein signature 2 17 5.2E-29 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 MB46_09625 725da2b1eb424d5710a5c9b8689eff75 112 PRINTS PR00340 P-II protein signature 83 103 5.2E-29 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 MB46_09625 725da2b1eb424d5710a5c9b8689eff75 112 PRINTS PR00340 P-II protein signature 23 41 5.2E-29 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 MB46_09625 725da2b1eb424d5710a5c9b8689eff75 112 PRINTS PR00340 P-II protein signature 52 75 5.2E-29 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 MB46_16305 ddf7f08a623987c841fbef3a8b5d480e 79 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 3 76 19.843 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_16305 ddf7f08a623987c841fbef3a8b5d480e 79 Gene3D G3DSA:4.10.640.10 1 76 5.1E-26 T 14-10-2018 IPR036870 Ribosomal protein S18 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_16305 ddf7f08a623987c841fbef3a8b5d480e 79 ProSitePatterns PS00057 Ribosomal protein S18 signature. 24 47 - T 14-10-2018 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_16305 ddf7f08a623987c841fbef3a8b5d480e 79 SUPERFAMILY SSF46911 6 74 3.01E-25 T 14-10-2018 IPR036870 Ribosomal protein S18 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_16305 ddf7f08a623987c841fbef3a8b5d480e 79 Pfam PF01084 Ribosomal protein S18 22 71 4.1E-23 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_16305 ddf7f08a623987c841fbef3a8b5d480e 79 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 24 75 6.0E-23 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_16305 ddf7f08a623987c841fbef3a8b5d480e 79 PRINTS PR00974 Ribosomal protein S18 family signature 31 41 6.7E-18 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_16305 ddf7f08a623987c841fbef3a8b5d480e 79 PRINTS PR00974 Ribosomal protein S18 family signature 49 63 6.7E-18 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_16305 ddf7f08a623987c841fbef3a8b5d480e 79 PRINTS PR00974 Ribosomal protein S18 family signature 63 73 6.7E-18 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_16305 ddf7f08a623987c841fbef3a8b5d480e 79 PRINTS PR00974 Ribosomal protein S18 family signature 41 48 6.7E-18 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_16305 ddf7f08a623987c841fbef3a8b5d480e 79 TIGRFAM TIGR00165 S18: ribosomal protein bS18 12 73 2.2E-23 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_07795 8800ce4972add2daea4e31dc1e46657c 152 SUPERFAMILY SSF82649 5 144 5.75E-31 T 14-10-2018 MB46_07795 8800ce4972add2daea4e31dc1e46657c 152 Pfam PF02657 Fe-S metabolism associated domain 16 143 2.7E-29 T 14-10-2018 IPR003808 Fe-S metabolism associated domain, SufE-like MB46_07795 8800ce4972add2daea4e31dc1e46657c 152 Gene3D G3DSA:3.90.1010.10 6 148 1.8E-48 T 14-10-2018 MB46_07135 cc7ca92c5086e37c90876877b6b12e04 544 Pfam PF07730 Histidine kinase 355 420 8.1E-10 T 14-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 MB46_07135 cc7ca92c5086e37c90876877b6b12e04 544 Gene3D G3DSA:3.30.565.10 419 543 9.0E-27 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MB46_07135 cc7ca92c5086e37c90876877b6b12e04 544 SMART SM00387 454 544 5.7E-8 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MB46_07135 cc7ca92c5086e37c90876877b6b12e04 544 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 460 541 1.1E-6 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MB46_07135 cc7ca92c5086e37c90876877b6b12e04 544 SUPERFAMILY SSF55874 428 541 1.18E-16 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MB46_13075 6cd7daa64a806e35399d3898a006165d 326 Gene3D G3DSA:3.40.50.12260 189 300 9.5E-58 T 14-10-2018 MB46_13075 6cd7daa64a806e35399d3898a006165d 326 Gene3D G3DSA:3.40.50.1980 55 316 9.5E-58 T 14-10-2018 MB46_13075 6cd7daa64a806e35399d3898a006165d 326 Pfam PF01497 Periplasmic binding protein 57 302 3.0E-39 T 14-10-2018 IPR002491 ABC transporter periplasmic binding domain MB46_13075 6cd7daa64a806e35399d3898a006165d 326 SUPERFAMILY SSF53807 33 310 2.24E-44 T 14-10-2018 MB46_16035 edbe0b871137ea5302d74a64e626c5af 474 Gene3D G3DSA:2.60.120.260 329 473 1.7E-6 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily MB46_12940 6963dd22d8bc83fea3a7f8d5a60710e1 211 Gene3D G3DSA:3.40.50.10420 4 210 1.4E-30 T 14-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily MB46_12940 6963dd22d8bc83fea3a7f8d5a60710e1 211 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 54 202 4.3E-24 T 14-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase MB46_12940 6963dd22d8bc83fea3a7f8d5a60710e1 211 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 6 201 2.7E-27 T 14-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase MB46_12940 6963dd22d8bc83fea3a7f8d5a60710e1 211 SUPERFAMILY SSF100950 5 208 2.51E-31 T 14-10-2018 IPR037171 NagB/RpiA transferase-like MB46_06365 c1f39790eb106f19970bccd4953a12f2 547 ProSitePatterns PS00211 ABC transporters family signature. 441 455 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_06365 c1f39790eb106f19970bccd4953a12f2 547 Pfam PF00005 ABC transporter 23 180 1.1E-23 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_06365 c1f39790eb106f19970bccd4953a12f2 547 Gene3D G3DSA:3.40.50.300 4 288 4.6E-78 T 14-10-2018 MB46_06365 c1f39790eb106f19970bccd4953a12f2 547 Gene3D G3DSA:3.40.50.300 294 547 8.9E-80 T 14-10-2018 MB46_06365 c1f39790eb106f19970bccd4953a12f2 547 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_06365 c1f39790eb106f19970bccd4953a12f2 547 Pfam PF00005 ABC transporter 318 468 1.6E-27 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_06365 c1f39790eb106f19970bccd4953a12f2 547 SUPERFAMILY SSF52540 3 257 5.22E-57 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_06365 c1f39790eb106f19970bccd4953a12f2 547 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 520 545 3.1E-5 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MB46_06365 c1f39790eb106f19970bccd4953a12f2 547 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 231 263 2.7E-6 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MB46_06365 c1f39790eb106f19970bccd4953a12f2 547 SUPERFAMILY SSF52540 296 540 4.62E-64 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_06365 c1f39790eb106f19970bccd4953a12f2 547 SMART SM00382 31 229 1.6E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_06365 c1f39790eb106f19970bccd4953a12f2 547 SMART SM00382 326 518 2.6E-21 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_15965 84097d2fc0962be6e970bc26a12a0937 218 SUPERFAMILY SSF52172 1 172 1.03E-18 T 14-10-2018 IPR011006 CheY-like superfamily MB46_15965 84097d2fc0962be6e970bc26a12a0937 218 Pfam PF00196 Bacterial regulatory proteins, luxR family 152 197 9.1E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_15965 84097d2fc0962be6e970bc26a12a0937 218 SMART SM00421 150 213 7.5E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_15965 84097d2fc0962be6e970bc26a12a0937 218 Gene3D G3DSA:3.40.50.2300 1 98 8.3E-16 T 14-10-2018 MB46_15965 84097d2fc0962be6e970bc26a12a0937 218 Gene3D G3DSA:1.10.10.10 105 217 2.0E-26 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_15965 84097d2fc0962be6e970bc26a12a0937 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 183 4.3E-8 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_15965 84097d2fc0962be6e970bc26a12a0937 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 153 167 4.3E-8 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_15965 84097d2fc0962be6e970bc26a12a0937 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 183 195 4.3E-8 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_15965 84097d2fc0962be6e970bc26a12a0937 218 SMART SM00448 1 122 1.2E-11 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MB46_15965 84097d2fc0962be6e970bc26a12a0937 218 Pfam PF00072 Response regulator receiver domain 3 96 2.2E-15 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MB46_08710 098f740efde38914de19640bf1a07474 300 Gene3D G3DSA:3.20.20.70 8 300 1.4E-149 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MB46_08710 098f740efde38914de19640bf1a07474 300 TIGRFAM TIGR00343 TIGR00343: pyridoxal 5'-phosphate synthase, synthase subunit Pdx1 15 300 1.3E-143 T 14-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 MB46_08710 098f740efde38914de19640bf1a07474 300 SUPERFAMILY SSF51366 24 270 1.98E-62 T 14-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 MB46_08710 098f740efde38914de19640bf1a07474 300 Hamap MF_01824 Pyridoxal 5'-phosphate synthase subunit PdxS [pdxS]. 10 300 51.828 T 14-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 MB46_08710 098f740efde38914de19640bf1a07474 300 Pfam PF01680 SOR/SNZ family 13 218 3.6E-106 T 14-10-2018 IPR033755 PdxS/SNZ N-terminal domain KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 MB46_08710 098f740efde38914de19640bf1a07474 300 PIRSF PIRSF029271 4 300 2.4E-148 T 14-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 MB46_08710 098f740efde38914de19640bf1a07474 300 ProSitePatterns PS01235 PdxS/SNZ family signature. 211 229 - T 14-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 MB46_04555 66e88d865ca5f2c1f9434aafdd39886c 841 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 442 644 4.9E-16 T 14-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 MB46_04555 66e88d865ca5f2c1f9434aafdd39886c 841 SUPERFAMILY SSF50677 245 440 3.35E-49 T 14-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 MB46_04555 66e88d865ca5f2c1f9434aafdd39886c 841 Pfam PF09334 tRNA synthetases class I (M) 59 199 2.6E-20 T 14-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 MB46_04555 66e88d865ca5f2c1f9434aafdd39886c 841 Gene3D G3DSA:3.40.50.620 53 602 5.6E-256 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MB46_04555 66e88d865ca5f2c1f9434aafdd39886c 841 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 60 71 - T 14-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 MB46_04555 66e88d865ca5f2c1f9434aafdd39886c 841 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 22 840 21.486 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 MB46_04555 66e88d865ca5f2c1f9434aafdd39886c 841 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 240 427 1.0E-61 T 14-10-2018 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 MB46_04555 66e88d865ca5f2c1f9434aafdd39886c 841 SUPERFAMILY SSF47323 653 839 1.87E-25 T 14-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 MB46_04555 66e88d865ca5f2c1f9434aafdd39886c 841 SUPERFAMILY SSF52374 21 645 4.02E-139 T 14-10-2018 MB46_04555 66e88d865ca5f2c1f9434aafdd39886c 841 Gene3D G3DSA:1.10.730.10 625 777 7.6E-31 T 14-10-2018 MB46_04555 66e88d865ca5f2c1f9434aafdd39886c 841 Gene3D G3DSA:3.90.740.10 247 440 5.6E-256 T 14-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 MB46_04555 66e88d865ca5f2c1f9434aafdd39886c 841 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 23 602 7.0E-245 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 MB46_04555 66e88d865ca5f2c1f9434aafdd39886c 841 Pfam PF08264 Anticodon-binding domain of tRNA 679 802 4.2E-13 T 14-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 MB46_04555 66e88d865ca5f2c1f9434aafdd39886c 841 PRINTS PR00985 Leucyl-tRNA synthetase signature 555 577 1.2E-50 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 MB46_04555 66e88d865ca5f2c1f9434aafdd39886c 841 PRINTS PR00985 Leucyl-tRNA synthetase signature 171 187 1.2E-50 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 MB46_04555 66e88d865ca5f2c1f9434aafdd39886c 841 PRINTS PR00985 Leucyl-tRNA synthetase signature 516 534 1.2E-50 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 MB46_04555 66e88d865ca5f2c1f9434aafdd39886c 841 PRINTS PR00985 Leucyl-tRNA synthetase signature 234 253 1.2E-50 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 MB46_04555 66e88d865ca5f2c1f9434aafdd39886c 841 PRINTS PR00985 Leucyl-tRNA synthetase signature 145 162 1.2E-50 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 MB46_04555 66e88d865ca5f2c1f9434aafdd39886c 841 PRINTS PR00985 Leucyl-tRNA synthetase signature 203 216 1.2E-50 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 MB46_04555 66e88d865ca5f2c1f9434aafdd39886c 841 PRINTS PR00985 Leucyl-tRNA synthetase signature 588 598 1.2E-50 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 MB46_04555 66e88d865ca5f2c1f9434aafdd39886c 841 Gene3D G3DSA:3.10.20.590 780 840 4.2E-16 T 14-10-2018 MB46_18240 5ddd64006c79afaf37762864a7b34038 324 Gene3D G3DSA:1.10.3720.10 74 324 5.5E-57 T 14-10-2018 IPR035906 MetI-like superfamily MB46_18240 5ddd64006c79afaf37762864a7b34038 324 SUPERFAMILY SSF161098 78 309 8.9E-52 T 14-10-2018 IPR035906 MetI-like superfamily MB46_18240 5ddd64006c79afaf37762864a7b34038 324 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 116 320 5.5E-17 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_13320 6322169b3215c9df78c0d611b9106c0c 294 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 86 292 1.1E-20 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_13320 6322169b3215c9df78c0d611b9106c0c 294 Gene3D G3DSA:1.10.3720.10 52 293 8.6E-72 T 14-10-2018 IPR035906 MetI-like superfamily MB46_13320 6322169b3215c9df78c0d611b9106c0c 294 SUPERFAMILY SSF161098 56 282 1.57E-62 T 14-10-2018 IPR035906 MetI-like superfamily MB46_05605 9908617c198759d5776c93b911943794 192 Pfam PF01381 Helix-turn-helix 15 68 9.2E-12 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MB46_05605 9908617c198759d5776c93b911943794 192 Gene3D G3DSA:2.60.120.10 74 191 3.4E-9 T 14-10-2018 IPR014710 RmlC-like jelly roll fold MB46_05605 9908617c198759d5776c93b911943794 192 SMART SM00530 14 69 1.1E-13 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MB46_05605 9908617c198759d5776c93b911943794 192 Pfam PF07883 Cupin domain 117 174 3.3E-8 T 14-10-2018 IPR013096 Cupin 2, conserved barrel MB46_05605 9908617c198759d5776c93b911943794 192 SUPERFAMILY SSF47413 4 74 7.32E-16 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MB46_05605 9908617c198759d5776c93b911943794 192 SUPERFAMILY SSF51182 68 174 9.99E-17 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily MB46_05605 9908617c198759d5776c93b911943794 192 Gene3D G3DSA:1.10.260.40 1 73 2.4E-18 T 14-10-2018 MB46_02690 110af2b6f2d5a676828b1a0e5fb54e51 552 SMART SM00388 329 396 2.8E-14 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MB46_02690 110af2b6f2d5a676828b1a0e5fb54e51 552 SUPERFAMILY SSF55874 390 545 5.11E-41 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MB46_02690 110af2b6f2d5a676828b1a0e5fb54e51 552 SUPERFAMILY SSF47384 317 391 1.8E-17 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MB46_02690 110af2b6f2d5a676828b1a0e5fb54e51 552 Pfam PF00512 His Kinase A (phospho-acceptor) domain 329 393 9.6E-14 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MB46_02690 110af2b6f2d5a676828b1a0e5fb54e51 552 SMART SM00387 436 548 5.6E-34 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MB46_02690 110af2b6f2d5a676828b1a0e5fb54e51 552 Gene3D G3DSA:3.30.565.10 398 548 1.3E-39 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MB46_02690 110af2b6f2d5a676828b1a0e5fb54e51 552 Gene3D G3DSA:1.10.287.130 330 395 7.0E-18 T 14-10-2018 MB46_02690 110af2b6f2d5a676828b1a0e5fb54e51 552 PRINTS PR00344 Bacterial sensor protein C-terminal signature 508 526 2.1E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MB46_02690 110af2b6f2d5a676828b1a0e5fb54e51 552 PRINTS PR00344 Bacterial sensor protein C-terminal signature 473 487 2.1E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MB46_02690 110af2b6f2d5a676828b1a0e5fb54e51 552 PRINTS PR00344 Bacterial sensor protein C-terminal signature 491 501 2.1E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MB46_02690 110af2b6f2d5a676828b1a0e5fb54e51 552 PRINTS PR00344 Bacterial sensor protein C-terminal signature 532 545 2.1E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MB46_02690 110af2b6f2d5a676828b1a0e5fb54e51 552 Gene3D G3DSA:3.30.450.20 191 329 2.2E-6 T 14-10-2018 MB46_02690 110af2b6f2d5a676828b1a0e5fb54e51 552 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 437 546 4.4E-22 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MB46_15070 99dc6b55b49c0bff8c02e8ca91b4c0d8 113 SUPERFAMILY SSF58113 19 94 2.62E-5 T 14-10-2018 MB46_15070 99dc6b55b49c0bff8c02e8ca91b4c0d8 113 Gene3D G3DSA:1.10.287.700 5 62 1.1E-5 T 14-10-2018 MB46_15070 99dc6b55b49c0bff8c02e8ca91b4c0d8 113 Gene3D G3DSA:1.10.287.700 63 108 7.6E-5 T 14-10-2018 MB46_15070 99dc6b55b49c0bff8c02e8ca91b4c0d8 113 Pfam PF05017 TMP repeat 52 61 99.0 T 14-10-2018 IPR007713 TMP repeat MB46_15070 99dc6b55b49c0bff8c02e8ca91b4c0d8 113 Pfam PF05017 TMP repeat 41 50 99.0 T 14-10-2018 IPR007713 TMP repeat MB46_15070 99dc6b55b49c0bff8c02e8ca91b4c0d8 113 Pfam PF05017 TMP repeat 63 72 280.0 T 14-10-2018 IPR007713 TMP repeat MB46_19505 3718c41b589b9d1c6079e10e9c0345af 552 Gene3D G3DSA:1.10.10.10 419 472 1.2E-5 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_19505 3718c41b589b9d1c6079e10e9c0345af 552 Pfam PF09339 IclR helix-turn-helix domain 426 466 5.3E-5 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 MB46_04345 6f525124407c09d8e2df48e9398cc8bb 325 Gene3D G3DSA:1.10.3720.10 77 323 2.9E-59 T 14-10-2018 IPR035906 MetI-like superfamily MB46_04345 6f525124407c09d8e2df48e9398cc8bb 325 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 117 318 2.0E-17 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_04345 6f525124407c09d8e2df48e9398cc8bb 325 SUPERFAMILY SSF161098 81 313 2.75E-53 T 14-10-2018 IPR035906 MetI-like superfamily MB46_13500 0a153ce526cf3763f5aeae38345aef86 190 Gene3D G3DSA:3.30.70.1730 2 166 1.0E-34 T 14-10-2018 MB46_13500 0a153ce526cf3763f5aeae38345aef86 190 Pfam PF00466 Ribosomal protein L10 4 98 2.5E-24 T 14-10-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 MB46_13500 0a153ce526cf3763f5aeae38345aef86 190 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 1 158 23.417 T 14-10-2018 IPR022973 Ribosomal protein L10 MB46_13500 0a153ce526cf3763f5aeae38345aef86 190 SUPERFAMILY SSF160369 1 159 4.18E-43 T 14-10-2018 MB46_13500 0a153ce526cf3763f5aeae38345aef86 190 ProSitePatterns PS01109 Ribosomal protein L10 signature. 6 40 - T 14-10-2018 IPR002363 Ribosomal protein L10, eubacterial, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MB46_13795 9e60a3a5b6428b04e6d5517606fbb9d1 523 Pfam PF00999 Sodium/hydrogen exchanger family 7 399 5.8E-50 T 14-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 MB46_13795 9e60a3a5b6428b04e6d5517606fbb9d1 523 TIGRFAM TIGR00831 a_cpa1: Na+/H+ antiporter 5 519 8.4E-91 T 14-10-2018 IPR004705 Cation/H+ exchanger, CPA1 family, bacteria GO:0006812|GO:0015299|GO:0016021 MB46_05370 03ce7fbbdff1a429fe33f57293fb404d 444 Gene3D G3DSA:3.40.50.620 1 344 1.6E-89 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MB46_05370 03ce7fbbdff1a429fe33f57293fb404d 444 Gene3D G3DSA:1.20.120.640 345 444 5.6E-15 T 14-10-2018 MB46_05370 03ce7fbbdff1a429fe33f57293fb404d 444 SUPERFAMILY SSF52374 31 350 6.4E-63 T 14-10-2018 MB46_05370 03ce7fbbdff1a429fe33f57293fb404d 444 TIGRFAM TIGR03447 mycothiol_MshC: cysteine--1-D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranoside ligase 2 444 3.4E-184 T 14-10-2018 IPR017812 Mycothiol ligase MshC GO:0010125|GO:0035446 MB46_05370 03ce7fbbdff1a429fe33f57293fb404d 444 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 260 281 3.6E-17 T 14-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 MB46_05370 03ce7fbbdff1a429fe33f57293fb404d 444 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 229 247 3.6E-17 T 14-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 MB46_05370 03ce7fbbdff1a429fe33f57293fb404d 444 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 76 85 3.6E-17 T 14-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 MB46_05370 03ce7fbbdff1a429fe33f57293fb404d 444 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 40 51 3.6E-17 T 14-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 MB46_05370 03ce7fbbdff1a429fe33f57293fb404d 444 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 38 350 3.5E-76 T 14-10-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 MB46_05370 03ce7fbbdff1a429fe33f57293fb404d 444 Hamap MF_01697 L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase [mshC]. 9 444 50.969 T 14-10-2018 IPR017812 Mycothiol ligase MshC GO:0010125|GO:0035446 MB46_07540 57b6b035dbd7ac31933e4b27652a15f0 497 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 341 348 - T 14-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 MB46_07540 57b6b035dbd7ac31933e4b27652a15f0 497 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 2 493 29.851 T 14-10-2018 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 MB46_07540 57b6b035dbd7ac31933e4b27652a15f0 497 SUPERFAMILY SSF53187 173 491 9.73E-101 T 14-10-2018 MB46_07540 57b6b035dbd7ac31933e4b27652a15f0 497 Gene3D G3DSA:3.40.220.10 3 160 1.2E-14 T 14-10-2018 MB46_07540 57b6b035dbd7ac31933e4b27652a15f0 497 PRINTS PR00481 Cytosol aminopeptidase signature 255 272 4.6E-43 T 14-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 MB46_07540 57b6b035dbd7ac31933e4b27652a15f0 497 PRINTS PR00481 Cytosol aminopeptidase signature 337 357 4.6E-43 T 14-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 MB46_07540 57b6b035dbd7ac31933e4b27652a15f0 497 PRINTS PR00481 Cytosol aminopeptidase signature 278 299 4.6E-43 T 14-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 MB46_07540 57b6b035dbd7ac31933e4b27652a15f0 497 PRINTS PR00481 Cytosol aminopeptidase signature 365 380 4.6E-43 T 14-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 MB46_07540 57b6b035dbd7ac31933e4b27652a15f0 497 PRINTS PR00481 Cytosol aminopeptidase signature 315 336 4.6E-43 T 14-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 MB46_07540 57b6b035dbd7ac31933e4b27652a15f0 497 Gene3D G3DSA:3.40.630.10 161 492 8.4E-114 T 14-10-2018 MB46_07540 57b6b035dbd7ac31933e4b27652a15f0 497 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 49 137 3.4E-7 T 14-10-2018 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 MB46_07540 57b6b035dbd7ac31933e4b27652a15f0 497 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 179 484 7.9E-106 T 14-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 MB46_07540 57b6b035dbd7ac31933e4b27652a15f0 497 SUPERFAMILY SSF52949 14 176 8.24E-11 T 14-10-2018 MB46_12220 ea6d6d368fb6fa09aed5df9a0e3bb331 100 Pfam PF13560 Helix-turn-helix domain 17 74 8.7E-11 T 14-10-2018 MB46_12220 ea6d6d368fb6fa09aed5df9a0e3bb331 100 Gene3D G3DSA:1.10.260.40 7 76 4.9E-29 T 14-10-2018 MB46_12220 ea6d6d368fb6fa09aed5df9a0e3bb331 100 SMART SM00530 20 74 4.1E-9 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MB46_12220 ea6d6d368fb6fa09aed5df9a0e3bb331 100 SUPERFAMILY SSF47413 11 77 1.78E-15 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MB46_14315 7a3d2064e8b9dc1f7c0b4dfd45904404 311 SMART SM00062 70 298 1.5E-32 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MB46_14315 7a3d2064e8b9dc1f7c0b4dfd45904404 311 Gene3D G3DSA:3.40.190.10 68 287 6.4E-54 T 14-10-2018 MB46_14315 7a3d2064e8b9dc1f7c0b4dfd45904404 311 SUPERFAMILY SSF53850 12 297 3.07E-48 T 14-10-2018 MB46_14315 7a3d2064e8b9dc1f7c0b4dfd45904404 311 Gene3D G3DSA:3.40.190.10 156 256 6.4E-54 T 14-10-2018 MB46_14315 7a3d2064e8b9dc1f7c0b4dfd45904404 311 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 71 295 8.4E-48 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MB46_14315 7a3d2064e8b9dc1f7c0b4dfd45904404 311 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 94 107 - T 14-10-2018 IPR018313 Solute-binding protein family 3, conserved site MB46_08130 7b2bc5ea40be7295f6c36888a0437eec 498 Gene3D G3DSA:3.40.720.10 3 475 6.3E-118 T 14-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 MB46_08130 7b2bc5ea40be7295f6c36888a0437eec 498 Pfam PF00884 Sulfatase 4 365 9.3E-55 T 14-10-2018 IPR000917 Sulfatase, N-terminal GO:0008484 MB46_08130 7b2bc5ea40be7295f6c36888a0437eec 498 SUPERFAMILY SSF53649 2 460 2.91E-105 T 14-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 MB46_07035 b59da4b552dc18277e639c6aba6500ad 647 Gene3D G3DSA:2.70.98.20 205 628 6.3E-176 T 14-10-2018 IPR036460 Copper amine oxidase, catalytic domain superfamily GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 Reactome: R-HSA-211945 MB46_07035 b59da4b552dc18277e639c6aba6500ad 647 Gene3D G3DSA:3.10.450.40 103 204 4.5E-26 T 14-10-2018 MB46_07035 b59da4b552dc18277e639c6aba6500ad 647 ProSitePatterns PS01164 Copper amine oxidase topaquinone signature. 372 385 - T 14-10-2018 IPR000269 Copper amine oxidase GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 Reactome: R-HSA-211945 MB46_07035 b59da4b552dc18277e639c6aba6500ad 647 Pfam PF02728 Copper amine oxidase, N3 domain 100 189 8.3E-15 T 14-10-2018 IPR015802 Copper amine oxidase, N3-terminal GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 KEGG: 00260+1.4.3.21|KEGG: 00350+1.4.3.21|KEGG: 00360+1.4.3.21|KEGG: 00410+1.4.3.21|KEGG: 00950+1.4.3.21|KEGG: 00960+1.4.3.21|MetaCyc: PWY-5751|Reactome: R-HSA-211945 MB46_07035 b59da4b552dc18277e639c6aba6500ad 647 Gene3D G3DSA:3.10.450.40 9 96 3.6E-28 T 14-10-2018 MB46_07035 b59da4b552dc18277e639c6aba6500ad 647 SUPERFAMILY SSF54416 11 97 3.6E-25 T 14-10-2018 IPR016182 Copper amine oxidase, N-terminal GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 Reactome: R-HSA-211945 MB46_07035 b59da4b552dc18277e639c6aba6500ad 647 SUPERFAMILY SSF54416 101 208 4.71E-29 T 14-10-2018 IPR016182 Copper amine oxidase, N-terminal GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 Reactome: R-HSA-211945 MB46_07035 b59da4b552dc18277e639c6aba6500ad 647 Pfam PF01179 Copper amine oxidase, enzyme domain 222 627 3.3E-151 T 14-10-2018 IPR015798 Copper amine oxidase, catalytic domain GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 Reactome: R-HSA-211945 MB46_07035 b59da4b552dc18277e639c6aba6500ad 647 SUPERFAMILY SSF49998 209 629 7.19E-157 T 14-10-2018 IPR036460 Copper amine oxidase, catalytic domain superfamily GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 Reactome: R-HSA-211945 MB46_07035 b59da4b552dc18277e639c6aba6500ad 647 ProSitePatterns PS01165 Copper amine oxidase copper-binding site signature. 588 601 - T 14-10-2018 IPR000269 Copper amine oxidase GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 Reactome: R-HSA-211945 MB46_03180 342f50c672dc450483bac963394e0e80 237 Pfam PF02517 CAAX protease self-immunity 135 224 2.4E-17 T 14-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 MB46_19055 99d6b320148f7dd0b685e541e4e556c2 226 Gene3D G3DSA:1.10.10.10 121 225 1.9E-37 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_19055 99d6b320148f7dd0b685e541e4e556c2 226 Pfam PF00072 Response regulator receiver domain 4 113 5.1E-29 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MB46_19055 99d6b320148f7dd0b685e541e4e556c2 226 SUPERFAMILY SSF52172 3 125 3.56E-41 T 14-10-2018 IPR011006 CheY-like superfamily MB46_19055 99d6b320148f7dd0b685e541e4e556c2 226 Gene3D G3DSA:3.40.50.2300 1 120 6.0E-37 T 14-10-2018 MB46_19055 99d6b320148f7dd0b685e541e4e556c2 226 SUPERFAMILY SSF46894 127 225 2.58E-29 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MB46_19055 99d6b320148f7dd0b685e541e4e556c2 226 SMART SM00862 148 224 1.4E-28 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MB46_19055 99d6b320148f7dd0b685e541e4e556c2 226 SMART SM00448 2 112 2.4E-44 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MB46_19055 99d6b320148f7dd0b685e541e4e556c2 226 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 224 4.6E-27 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MB46_08890 d42eed8bbaa2194f513a75f01fe35397 401 Gene3D G3DSA:3.30.420.40 70 205 5.9E-35 T 14-10-2018 MB46_08890 d42eed8bbaa2194f513a75f01fe35397 401 SUPERFAMILY SSF53067 73 386 7.41E-49 T 14-10-2018 MB46_08890 d42eed8bbaa2194f513a75f01fe35397 401 Pfam PF00480 ROK family 110 335 3.5E-47 T 14-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 MB46_08890 d42eed8bbaa2194f513a75f01fe35397 401 Gene3D G3DSA:1.10.10.10 2 69 3.5E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_08890 d42eed8bbaa2194f513a75f01fe35397 401 ProSitePatterns PS01125 ROK family signature. 209 236 - T 14-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 MB46_08890 d42eed8bbaa2194f513a75f01fe35397 401 SUPERFAMILY SSF46785 3 64 5.05E-11 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_08890 d42eed8bbaa2194f513a75f01fe35397 401 Gene3D G3DSA:3.30.420.40 206 358 8.9E-38 T 14-10-2018 MB46_08890 d42eed8bbaa2194f513a75f01fe35397 401 Pfam PF13412 Winged helix-turn-helix DNA-binding 9 49 4.0E-5 T 14-10-2018 MB46_13545 5e5a78260aeea682d1518e0f9d315672 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 158 172 1.9E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_13545 5e5a78260aeea682d1518e0f9d315672 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 188 200 1.9E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_13545 5e5a78260aeea682d1518e0f9d315672 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 172 188 1.9E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_13545 5e5a78260aeea682d1518e0f9d315672 218 ProSitePatterns PS00622 LuxR-type HTH domain signature. 172 199 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_13545 5e5a78260aeea682d1518e0f9d315672 218 SUPERFAMILY SSF52172 7 140 5.27E-25 T 14-10-2018 IPR011006 CheY-like superfamily MB46_13545 5e5a78260aeea682d1518e0f9d315672 218 Pfam PF00196 Bacterial regulatory proteins, luxR family 157 212 1.3E-19 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_13545 5e5a78260aeea682d1518e0f9d315672 218 SMART SM00421 155 212 6.1E-23 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_13545 5e5a78260aeea682d1518e0f9d315672 218 Pfam PF00072 Response regulator receiver domain 10 122 5.2E-17 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MB46_13545 5e5a78260aeea682d1518e0f9d315672 218 SUPERFAMILY SSF46894 150 217 3.03E-22 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MB46_13545 5e5a78260aeea682d1518e0f9d315672 218 SMART SM00448 8 122 4.9E-19 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MB46_13545 5e5a78260aeea682d1518e0f9d315672 218 Gene3D G3DSA:3.40.50.12740 8 218 5.1E-56 T 14-10-2018 MB46_07505 233b6f1db4c3ecfdab90d3ad54acc51c 394 SUPERFAMILY SSF103473 3 384 6.93E-49 T 14-10-2018 IPR036259 MFS transporter superfamily MB46_07505 233b6f1db4c3ecfdab90d3ad54acc51c 394 Gene3D G3DSA:1.20.1250.20 2 374 1.0E-43 T 14-10-2018 MB46_07505 233b6f1db4c3ecfdab90d3ad54acc51c 394 Pfam PF07690 Major Facilitator Superfamily 4 250 1.1E-24 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MB46_17070 d1ecbd37534a1b55525626a14973c27d 621 SUPERFAMILY SSF53067 1 159 1.78E-56 T 14-10-2018 MB46_17070 d1ecbd37534a1b55525626a14973c27d 621 Pfam PF00012 Hsp70 protein 4 78 3.6E-28 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MB46_17070 d1ecbd37534a1b55525626a14973c27d 621 Pfam PF00012 Hsp70 protein 79 580 8.5E-203 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MB46_17070 d1ecbd37534a1b55525626a14973c27d 621 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 615 34.571 T 14-10-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613|Reactome: R-HSA-8950505 MB46_17070 d1ecbd37534a1b55525626a14973c27d 621 Gene3D G3DSA:1.20.1270.10 484 584 5.0E-26 T 14-10-2018 IPR029048 Heat shock protein 70kD, C-terminal domain superfamily Reactome: R-HSA-3371453 MB46_17070 d1ecbd37534a1b55525626a14973c27d 621 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 168 181 - T 14-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 MB46_17070 d1ecbd37534a1b55525626a14973c27d 621 Gene3D G3DSA:3.30.420.40 5 353 4.8E-138 T 14-10-2018 MB46_17070 d1ecbd37534a1b55525626a14973c27d 621 SUPERFAMILY SSF100920 361 517 5.23E-61 T 14-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 MB46_17070 d1ecbd37534a1b55525626a14973c27d 621 PRINTS PR00301 70kDa heat shock protein signature 174 184 2.5E-74 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MB46_17070 d1ecbd37534a1b55525626a14973c27d 621 PRINTS PR00301 70kDa heat shock protein signature 31 43 2.5E-74 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MB46_17070 d1ecbd37534a1b55525626a14973c27d 621 PRINTS PR00301 70kDa heat shock protein signature 3 16 2.5E-74 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MB46_17070 d1ecbd37534a1b55525626a14973c27d 621 PRINTS PR00301 70kDa heat shock protein signature 54 62 2.5E-74 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MB46_17070 d1ecbd37534a1b55525626a14973c27d 621 PRINTS PR00301 70kDa heat shock protein signature 310 326 2.5E-74 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MB46_17070 d1ecbd37534a1b55525626a14973c27d 621 PRINTS PR00301 70kDa heat shock protein signature 365 384 2.5E-74 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MB46_17070 d1ecbd37534a1b55525626a14973c27d 621 PRINTS PR00301 70kDa heat shock protein signature 446 462 2.5E-74 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MB46_17070 d1ecbd37534a1b55525626a14973c27d 621 PRINTS PR00301 70kDa heat shock protein signature 114 134 2.5E-74 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MB46_17070 d1ecbd37534a1b55525626a14973c27d 621 PRINTS PR00301 70kDa heat shock protein signature 342 362 2.5E-74 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MB46_17070 d1ecbd37534a1b55525626a14973c27d 621 SUPERFAMILY SSF53067 163 359 1.43E-58 T 14-10-2018 MB46_17070 d1ecbd37534a1b55525626a14973c27d 621 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 313 327 - T 14-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 MB46_17070 d1ecbd37534a1b55525626a14973c27d 621 Gene3D G3DSA:3.30.420.40 162 342 4.8E-138 T 14-10-2018 MB46_17070 d1ecbd37534a1b55525626a14973c27d 621 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 4 580 9.1E-264 T 14-10-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613|Reactome: R-HSA-8950505 MB46_17070 d1ecbd37534a1b55525626a14973c27d 621 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 14-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 MB46_17070 d1ecbd37534a1b55525626a14973c27d 621 Gene3D G3DSA:2.60.34.10 354 481 2.6E-57 T 14-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 MB46_17070 d1ecbd37534a1b55525626a14973c27d 621 Gene3D G3DSA:3.90.640.10 205 291 4.8E-138 T 14-10-2018 MB46_18225 3c22f111b889616c544572a71ffac2e1 415 ProSitePatterns PS01125 ROK family signature. 234 261 - T 14-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 MB46_18225 3c22f111b889616c544572a71ffac2e1 415 Pfam PF00480 ROK family 102 398 2.2E-58 T 14-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 MB46_18225 3c22f111b889616c544572a71ffac2e1 415 SUPERFAMILY SSF53067 101 401 5.86E-56 T 14-10-2018 MB46_18225 3c22f111b889616c544572a71ffac2e1 415 Pfam PF13412 Winged helix-turn-helix DNA-binding 39 75 6.0E-5 T 14-10-2018 MB46_18225 3c22f111b889616c544572a71ffac2e1 415 SUPERFAMILY SSF46785 35 91 1.32E-8 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_18225 3c22f111b889616c544572a71ffac2e1 415 Gene3D G3DSA:3.30.420.40 224 384 7.2E-88 T 14-10-2018 MB46_18225 3c22f111b889616c544572a71ffac2e1 415 Gene3D G3DSA:3.30.420.40 106 393 7.2E-88 T 14-10-2018 MB46_18225 3c22f111b889616c544572a71ffac2e1 415 Gene3D G3DSA:1.10.10.10 32 94 1.4E-10 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_12005 5bc85f7595907a696279d3a3756091f8 310 Gene3D G3DSA:3.40.190.10 161 252 3.0E-52 T 14-10-2018 MB46_12005 5bc85f7595907a696279d3a3756091f8 310 SMART SM00062 75 294 6.8E-48 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MB46_12005 5bc85f7595907a696279d3a3756091f8 310 Gene3D G3DSA:3.40.190.10 76 290 3.0E-52 T 14-10-2018 MB46_12005 5bc85f7595907a696279d3a3756091f8 310 SUPERFAMILY SSF53850 73 292 3.79E-51 T 14-10-2018 MB46_12005 5bc85f7595907a696279d3a3756091f8 310 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 76 291 4.1E-49 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MB46_05485 1c5fa9967697b6af8c258f94a979238f 469 SUPERFAMILY SSF53383 113 452 2.11E-72 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MB46_05485 1c5fa9967697b6af8c258f94a979238f 469 SMART SM00345 27 86 4.6E-15 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MB46_05485 1c5fa9967697b6af8c258f94a979238f 469 SUPERFAMILY SSF46785 17 87 8.13E-16 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_05485 1c5fa9967697b6af8c258f94a979238f 469 Gene3D G3DSA:3.40.640.10 134 352 6.0E-73 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MB46_05485 1c5fa9967697b6af8c258f94a979238f 469 Gene3D G3DSA:1.10.10.10 14 87 6.2E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_05485 1c5fa9967697b6af8c258f94a979238f 469 Pfam PF00155 Aminotransferase class I and II 138 443 4.3E-24 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MB46_05485 1c5fa9967697b6af8c258f94a979238f 469 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 60 76 1.8E-6 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MB46_05485 1c5fa9967697b6af8c258f94a979238f 469 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 46 60 1.8E-6 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MB46_05485 1c5fa9967697b6af8c258f94a979238f 469 Pfam PF00392 Bacterial regulatory proteins, gntR family 24 84 6.8E-15 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MB46_05485 1c5fa9967697b6af8c258f94a979238f 469 Gene3D G3DSA:3.90.1150.10 116 451 6.0E-73 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MB46_14335 62784b769f58010f456b8df70ed6bdd5 580 TIGRFAM TIGR00173 menD: 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase 4 447 3.1E-109 T 14-10-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 MB46_14335 62784b769f58010f456b8df70ed6bdd5 580 Gene3D G3DSA:3.40.50.970 379 577 1.2E-62 T 14-10-2018 MB46_14335 62784b769f58010f456b8df70ed6bdd5 580 Gene3D G3DSA:3.40.50.1220 221 371 4.3E-19 T 14-10-2018 MB46_14335 62784b769f58010f456b8df70ed6bdd5 580 SUPERFAMILY SSF52518 1 174 2.21E-31 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold MB46_14335 62784b769f58010f456b8df70ed6bdd5 580 Gene3D G3DSA:3.40.50.970 1 184 2.7E-63 T 14-10-2018 MB46_14335 62784b769f58010f456b8df70ed6bdd5 580 SUPERFAMILY SSF52518 423 561 1.95E-15 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold MB46_14335 62784b769f58010f456b8df70ed6bdd5 580 PIRSF PIRSF004983 1 580 1.9E-128 T 14-10-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 MB46_14335 62784b769f58010f456b8df70ed6bdd5 580 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 1 166 2.8E-31 T 14-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 MB46_14335 62784b769f58010f456b8df70ed6bdd5 580 Hamap MF_01659 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase [menD]. 1 577 31.093 T 14-10-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 MB46_09150 94aefcda8093c81e77e3ed1d5a777b48 209 Pfam PF00436 Single-strand binding protein family 2 104 1.4E-19 T 14-10-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 MB46_09150 94aefcda8093c81e77e3ed1d5a777b48 209 Gene3D G3DSA:2.40.50.140 1 117 1.1E-33 T 14-10-2018 MB46_09150 94aefcda8093c81e77e3ed1d5a777b48 209 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 1 111 1.1E-16 T 14-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 MB46_09150 94aefcda8093c81e77e3ed1d5a777b48 209 SUPERFAMILY SSF50249 1 140 1.65E-27 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold MB46_00645 2c8b2b662523af5c834b8230ffd32f61 121 Gene3D G3DSA:1.10.10.10 6 111 1.1E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_00645 2c8b2b662523af5c834b8230ffd32f61 121 SMART SM00418 16 95 2.1E-16 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MB46_00645 2c8b2b662523af5c834b8230ffd32f61 121 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 51 66 3.0E-9 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MB46_00645 2c8b2b662523af5c834b8230ffd32f61 121 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 66 81 3.0E-9 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MB46_00645 2c8b2b662523af5c834b8230ffd32f61 121 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 18 33 3.0E-9 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MB46_00645 2c8b2b662523af5c834b8230ffd32f61 121 SUPERFAMILY SSF46785 8 95 6.54E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_00645 2c8b2b662523af5c834b8230ffd32f61 121 Pfam PF12840 Helix-turn-helix domain 16 72 1.3E-8 T 14-10-2018 MB46_14985 707131008564e00607b01f24cc6bcec9 372 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 171 202 - T 14-10-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 MB46_14985 707131008564e00607b01f24cc6bcec9 372 SMART SM00922 116 221 5.4E-16 T 14-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal MB46_14985 707131008564e00607b01f24cc6bcec9 372 SUPERFAMILY SSF54826 5 103 2.89E-28 T 14-10-2018 MB46_14985 707131008564e00607b01f24cc6bcec9 372 Gene3D G3DSA:3.30.390.10 2 364 3.3E-138 T 14-10-2018 IPR029017 Enolase-like, N-terminal MB46_14985 707131008564e00607b01f24cc6bcec9 372 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 7 98 2.2E-23 T 14-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain MB46_14985 707131008564e00607b01f24cc6bcec9 372 Gene3D G3DSA:3.20.20.120 93 334 3.3E-138 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily MB46_14985 707131008564e00607b01f24cc6bcec9 372 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 73 98 - T 14-10-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 MB46_14985 707131008564e00607b01f24cc6bcec9 372 SUPERFAMILY SSF51604 86 349 1.9E-71 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily MB46_14985 707131008564e00607b01f24cc6bcec9 372 Pfam PF13378 Enolase C-terminal domain-like 120 345 6.9E-58 T 14-10-2018 IPR029065 Enolase C-terminal domain-like MB46_10170 d4c8c71aaadc6ba4671b5e47c6cfb70d 531 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 109 283 3.8E-62 T 14-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 MB46_10170 d4c8c71aaadc6ba4671b5e47c6cfb70d 531 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 8 315 6.6E-33 T 14-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 MB46_10170 d4c8c71aaadc6ba4671b5e47c6cfb70d 531 Gene3D G3DSA:3.30.70.260 456 530 1.7E-24 T 14-10-2018 MB46_10170 d4c8c71aaadc6ba4671b5e47c6cfb70d 531 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 146 173 - T 14-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 MB46_10170 d4c8c71aaadc6ba4671b5e47c6cfb70d 531 SUPERFAMILY SSF55021 454 527 1.46E-15 T 14-10-2018 MB46_10170 d4c8c71aaadc6ba4671b5e47c6cfb70d 531 Gene3D G3DSA:3.30.1330.90 317 454 4.7E-42 T 14-10-2018 IPR029009 Allosteric substrate binding domain superfamily Reactome: R-HSA-977347 MB46_10170 d4c8c71aaadc6ba4671b5e47c6cfb70d 531 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 223 239 - T 14-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site MB46_10170 d4c8c71aaadc6ba4671b5e47c6cfb70d 531 SUPERFAMILY SSF51735 103 283 5.46E-57 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_10170 d4c8c71aaadc6ba4671b5e47c6cfb70d 531 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 194 216 - T 14-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site MB46_10170 d4c8c71aaadc6ba4671b5e47c6cfb70d 531 SUPERFAMILY SSF52283 18 131 1.66E-36 T 14-10-2018 MB46_10170 d4c8c71aaadc6ba4671b5e47c6cfb70d 531 Gene3D G3DSA:3.40.50.720 100 281 3.0E-118 T 14-10-2018 MB46_10170 d4c8c71aaadc6ba4671b5e47c6cfb70d 531 SUPERFAMILY SSF143548 322 451 3.66E-32 T 14-10-2018 IPR029009 Allosteric substrate binding domain superfamily Reactome: R-HSA-977347 MB46_10170 d4c8c71aaadc6ba4671b5e47c6cfb70d 531 Gene3D G3DSA:3.40.50.720 9 307 3.0E-118 T 14-10-2018 MB46_10170 d4c8c71aaadc6ba4671b5e47c6cfb70d 531 Pfam PF01842 ACT domain 457 517 2.6E-10 T 14-10-2018 IPR002912 ACT domain MB46_10170 d4c8c71aaadc6ba4671b5e47c6cfb70d 531 TIGRFAM TIGR01327 PGDH: phosphoglycerate dehydrogenase 8 524 2.8E-184 T 14-10-2018 IPR006236 D-3-phosphoglycerate dehydrogenase GO:0004617|GO:0006564 KEGG: 00260+1.1.1.95|KEGG: 00680+1.1.1.95|Reactome: R-HSA-977347 MB46_15265 9930841e9db8c1c3c92dfb66b04755a0 683 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 182 272 8.3E-16 T 14-10-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 MB46_15265 9930841e9db8c1c3c92dfb66b04755a0 683 Gene3D G3DSA:3.40.930.10 1 146 5.4E-36 T 14-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 MB46_15265 9930841e9db8c1c3c92dfb66b04755a0 683 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 4 146 3.1E-28 T 14-10-2018 IPR002178 PTS EIIA type-2 domain MB46_15265 9930841e9db8c1c3c92dfb66b04755a0 683 TIGRFAM TIGR00848 fruA: PTS system, fructose subfamily, IIA component 4 131 5.8E-33 T 14-10-2018 IPR004715 Phosphotransferase system, IIA component fructose subfamily GO:0008982|GO:0009401|GO:0016021 MB46_15265 9930841e9db8c1c3c92dfb66b04755a0 683 Gene3D G3DSA:3.40.50.2300 169 278 4.5E-35 T 14-10-2018 MB46_15265 9930841e9db8c1c3c92dfb66b04755a0 683 SUPERFAMILY SSF52794 179 275 2.96E-29 T 14-10-2018 IPR036095 PTS system IIB component-like superfamily GO:0008982|GO:0009401 MB46_15265 9930841e9db8c1c3c92dfb66b04755a0 683 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 306 660 2.8E-99 T 14-10-2018 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 MB46_15265 9930841e9db8c1c3c92dfb66b04755a0 683 SUPERFAMILY SSF55804 3 145 1.44E-30 T 14-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 MB46_15265 9930841e9db8c1c3c92dfb66b04755a0 683 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 181 263 1.9E-23 T 14-10-2018 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 KEGG: 00051+2.7.1.202 MB46_00140 22db1df11a16862624d0bc9f29ecfa18 356 Gene3D G3DSA:3.40.50.2300 73 330 7.8E-65 T 14-10-2018 MB46_00140 22db1df11a16862624d0bc9f29ecfa18 356 Pfam PF13377 Periplasmic binding protein-like domain 191 356 8.9E-38 T 14-10-2018 MB46_00140 22db1df11a16862624d0bc9f29ecfa18 356 SUPERFAMILY SSF47413 17 77 3.26E-16 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MB46_00140 22db1df11a16862624d0bc9f29ecfa18 356 Gene3D G3DSA:3.40.50.2300 183 316 7.8E-65 T 14-10-2018 MB46_00140 22db1df11a16862624d0bc9f29ecfa18 356 SUPERFAMILY SSF53822 81 356 5.89E-60 T 14-10-2018 IPR028082 Periplasmic binding protein-like I MB46_00140 22db1df11a16862624d0bc9f29ecfa18 356 Pfam PF00356 Bacterial regulatory proteins, lacI family 19 66 1.9E-15 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MB46_00140 22db1df11a16862624d0bc9f29ecfa18 356 ProSitePatterns PS00356 LacI-type HTH domain signature. 20 38 - T 14-10-2018 MB46_00140 22db1df11a16862624d0bc9f29ecfa18 356 Gene3D G3DSA:1.10.260.40 9 72 1.0E-21 T 14-10-2018 MB46_00140 22db1df11a16862624d0bc9f29ecfa18 356 SMART SM00354 17 89 2.6E-19 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MB46_16560 7108098f6387130eb2c7fd8ddf5741b6 373 Gene3D G3DSA:3.40.640.10 50 279 5.5E-109 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MB46_16560 7108098f6387130eb2c7fd8ddf5741b6 373 Pfam PF00155 Aminotransferase class I and II 39 358 3.9E-48 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MB46_16560 7108098f6387130eb2c7fd8ddf5741b6 373 SUPERFAMILY SSF53383 31 362 4.03E-69 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MB46_16560 7108098f6387130eb2c7fd8ddf5741b6 373 Gene3D G3DSA:3.90.1150.10 20 360 5.5E-109 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MB46_15915 fdecf4b4567ac16c65e38d9db353bd91 400 Gene3D G3DSA:1.20.1250.20 203 386 1.3E-18 T 14-10-2018 MB46_15915 fdecf4b4567ac16c65e38d9db353bd91 400 Gene3D G3DSA:1.20.1250.20 7 196 7.7E-13 T 14-10-2018 MB46_15915 fdecf4b4567ac16c65e38d9db353bd91 400 SUPERFAMILY SSF103473 3 389 1.44E-37 T 14-10-2018 IPR036259 MFS transporter superfamily MB46_15915 fdecf4b4567ac16c65e38d9db353bd91 400 Pfam PF07690 Major Facilitator Superfamily 241 382 1.1E-11 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MB46_07970 7d29b37a82dbe4f603656b7b5baa9493 332 SUPERFAMILY SSF55729 128 317 1.31E-24 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase MB46_07970 7d29b37a82dbe4f603656b7b5baa9493 332 SUPERFAMILY SSF55729 11 157 2.15E-7 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase MB46_07970 7d29b37a82dbe4f603656b7b5baa9493 332 Gene3D G3DSA:3.40.630.30 10 330 3.3E-64 T 14-10-2018 MB46_07970 7d29b37a82dbe4f603656b7b5baa9493 332 Pfam PF00583 Acetyltransferase (GNAT) family 223 314 3.5E-8 T 14-10-2018 IPR000182 GNAT domain MB46_04605 14b8a0981eff6c6de8256f1f2ed4d273 282 Pfam PF11296 Protein of unknown function (DUF3097) 15 278 2.1E-115 T 14-10-2018 IPR021447 Protein of unknown function DUF3097 MB46_04595 69f02a1069fbf3caeb30bfc494284e6f 409 Pfam PF04055 Radical SAM superfamily 36 211 2.7E-19 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MB46_04595 69f02a1069fbf3caeb30bfc494284e6f 409 SMART SM00729 30 258 1.1E-53 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 MB46_04595 69f02a1069fbf3caeb30bfc494284e6f 409 SUPERFAMILY SSF102114 26 408 2.75E-100 T 14-10-2018 MB46_04595 69f02a1069fbf3caeb30bfc494284e6f 409 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 32 379 1.0E-71 T 14-10-2018 IPR004559 Oxygen-independent coproporphyrinogen III oxidase-like GO:0004109|GO:0005737|GO:0006779|GO:0055114 MB46_04595 69f02a1069fbf3caeb30bfc494284e6f 409 Gene3D G3DSA:3.80.30.20 15 336 3.2E-91 T 14-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe MB46_13660 18cd55f23741e555fe246fcf5e9f64a3 338 Pfam PF03171 2OG-Fe(II) oxygenase superfamily 182 277 2.3E-20 T 14-10-2018 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 MB46_13660 18cd55f23741e555fe246fcf5e9f64a3 338 PRINTS PR00682 Isopenicillin N synthase signature 152 168 8.9E-10 T 14-10-2018 MB46_13660 18cd55f23741e555fe246fcf5e9f64a3 338 PRINTS PR00682 Isopenicillin N synthase signature 29 46 8.9E-10 T 14-10-2018 MB46_13660 18cd55f23741e555fe246fcf5e9f64a3 338 PRINTS PR00682 Isopenicillin N synthase signature 265 283 8.9E-10 T 14-10-2018 MB46_13660 18cd55f23741e555fe246fcf5e9f64a3 338 Pfam PF14226 non-haem dioxygenase in morphine synthesis N-terminal 7 130 7.0E-34 T 14-10-2018 IPR026992 Non-haem dioxygenase N-terminal domain MB46_13660 18cd55f23741e555fe246fcf5e9f64a3 338 SUPERFAMILY SSF51197 4 283 8.24E-82 T 14-10-2018 MB46_13660 18cd55f23741e555fe246fcf5e9f64a3 338 Gene3D G3DSA:2.60.120.330 2 310 9.8E-81 T 14-10-2018 IPR027443 Isopenicillin N synthase-like MB46_12245 86d4ab16de0c0294477cad6ac002d729 465 Gene3D G3DSA:3.30.1330.90 11 160 6.9E-50 T 14-10-2018 IPR029009 Allosteric substrate binding domain superfamily Reactome: R-HSA-977347 MB46_12245 86d4ab16de0c0294477cad6ac002d729 465 SUPERFAMILY SSF143548 17 157 9.15E-39 T 14-10-2018 IPR029009 Allosteric substrate binding domain superfamily Reactome: R-HSA-977347 MB46_12245 86d4ab16de0c0294477cad6ac002d729 465 Pfam PF03313 Serine dehydratase alpha chain 194 459 3.1E-97 T 14-10-2018 IPR005130 Serine dehydratase-like, alpha subunit MB46_12245 86d4ab16de0c0294477cad6ac002d729 465 TIGRFAM TIGR00720 sda_mono: L-serine ammonia-lyase 4 462 5.3E-195 T 14-10-2018 IPR004644 Iron-sulphur-dependent L-serine dehydratase single chain form GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 MB46_12245 86d4ab16de0c0294477cad6ac002d729 465 Pfam PF03315 Serine dehydratase beta chain 5 155 8.2E-54 T 14-10-2018 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 MB46_12020 77971ae8862f16c9414e433a28467f0b 433 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 234 274 - T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MB46_12020 77971ae8862f16c9414e433a28467f0b 433 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 4 426 5.4E-167 T 14-10-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 MB46_12020 77971ae8862f16c9414e433a28467f0b 433 Gene3D G3DSA:3.40.640.10 69 320 3.6E-153 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MB46_12020 77971ae8862f16c9414e433a28467f0b 433 Pfam PF00202 Aminotransferase class-III 33 422 1.7E-73 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MB46_12020 77971ae8862f16c9414e433a28467f0b 433 SUPERFAMILY SSF53383 2 426 1.35E-106 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MB46_12020 77971ae8862f16c9414e433a28467f0b 433 Gene3D G3DSA:3.90.1150.10 6 421 3.6E-153 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MB46_12020 77971ae8862f16c9414e433a28467f0b 433 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 3 430 95.962 T 14-10-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 MB46_03520 5a7319414f16392dcd971fea03aafde9 498 Gene3D G3DSA:1.20.1730.10 23 488 4.4E-50 T 14-10-2018 IPR038377 Sodium/glucose symporter superfamily MB46_03520 5a7319414f16392dcd971fea03aafde9 498 Pfam PF00474 Sodium:solute symporter family 34 422 1.2E-46 T 14-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 MB46_09005 f674e019e32b8b01690aee9eff5cc8b3 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 2.1E-5 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_09005 f674e019e32b8b01690aee9eff5cc8b3 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 2.1E-5 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_09005 f674e019e32b8b01690aee9eff5cc8b3 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 2.1E-5 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_09005 f674e019e32b8b01690aee9eff5cc8b3 255 SUPERFAMILY SSF51735 5 237 3.32E-54 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_09005 f674e019e32b8b01690aee9eff5cc8b3 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 1.8E-21 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_09005 f674e019e32b8b01690aee9eff5cc8b3 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.8E-21 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_09005 f674e019e32b8b01690aee9eff5cc8b3 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 1.8E-21 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_09005 f674e019e32b8b01690aee9eff5cc8b3 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 1.8E-21 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_09005 f674e019e32b8b01690aee9eff5cc8b3 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 1.8E-21 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_09005 f674e019e32b8b01690aee9eff5cc8b3 255 Pfam PF00106 short chain dehydrogenase 7 190 6.6E-45 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_09005 f674e019e32b8b01690aee9eff5cc8b3 255 Gene3D G3DSA:3.40.50.720 2 253 9.8E-56 T 14-10-2018 MB46_00505 ef97e05bf529ebcaa8ac5c727de71e2c 470 SUPERFAMILY SSF53720 17 469 1.96E-131 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 MB46_00505 ef97e05bf529ebcaa8ac5c727de71e2c 470 Gene3D G3DSA:3.40.605.10 24 455 8.7E-140 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 MB46_00505 ef97e05bf529ebcaa8ac5c727de71e2c 470 Gene3D G3DSA:3.40.309.10 248 436 8.7E-140 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 MB46_00505 ef97e05bf529ebcaa8ac5c727de71e2c 470 Pfam PF00171 Aldehyde dehydrogenase family 19 466 1.4E-139 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 MB46_15510 9c23dc572335465667b85f00c7da602b 247 SMART SM00862 169 243 1.4E-25 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MB46_15510 9c23dc572335465667b85f00c7da602b 247 SMART SM00448 23 134 3.1E-41 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MB46_15510 9c23dc572335465667b85f00c7da602b 247 Pfam PF00486 Transcriptional regulatory protein, C terminal 169 243 9.1E-25 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MB46_15510 9c23dc572335465667b85f00c7da602b 247 SUPERFAMILY SSF52172 21 198 1.71E-40 T 14-10-2018 IPR011006 CheY-like superfamily MB46_15510 9c23dc572335465667b85f00c7da602b 247 Pfam PF00072 Response regulator receiver domain 26 134 9.1E-26 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MB46_15510 9c23dc572335465667b85f00c7da602b 247 Gene3D G3DSA:1.10.10.10 149 247 1.2E-32 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_15510 9c23dc572335465667b85f00c7da602b 247 Gene3D G3DSA:3.40.50.2300 14 148 4.6E-36 T 14-10-2018 MB46_09395 28503a166cbc7fddcad24d60aec2c4f8 195 Gene3D G3DSA:1.10.3130.10 3 69 2.4E-17 T 14-10-2018 MB46_09395 28503a166cbc7fddcad24d60aec2c4f8 195 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 120 153 1.9E-6 T 14-10-2018 IPR001451 Hexapeptide repeat MB46_09395 28503a166cbc7fddcad24d60aec2c4f8 195 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 74 111 1.6E-5 T 14-10-2018 IPR001451 Hexapeptide repeat MB46_09395 28503a166cbc7fddcad24d60aec2c4f8 195 PIRSF PIRSF000441 2 190 7.8E-78 T 14-10-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|KEGG: 00999+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|MetaCyc: PWY-7870 MB46_09395 28503a166cbc7fddcad24d60aec2c4f8 195 SUPERFAMILY SSF51161 6 169 1.23E-50 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily MB46_09395 28503a166cbc7fddcad24d60aec2c4f8 195 Gene3D G3DSA:2.160.10.10 70 187 2.5E-35 T 14-10-2018 MB46_09395 28503a166cbc7fddcad24d60aec2c4f8 195 TIGRFAM TIGR01172 cysE: serine O-acetyltransferase 7 168 2.5E-69 T 14-10-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|KEGG: 00999+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|MetaCyc: PWY-7870 MB46_13215 3e2ec5da3ba924672b69b8f119953885 341 Gene3D G3DSA:3.20.20.100 15 340 1.9E-106 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily MB46_13215 3e2ec5da3ba924672b69b8f119953885 341 Pfam PF00248 Aldo/keto reductase family 28 333 5.9E-64 T 14-10-2018 IPR023210 NADP-dependent oxidoreductase domain MB46_13215 3e2ec5da3ba924672b69b8f119953885 341 SUPERFAMILY SSF51430 13 333 1.7E-83 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily MB46_16005 ce23af234ebb4821a7570a81046f76bc 482 PRINTS PR00419 Adrenodoxin reductase family signature 3 25 1.4E-5 T 14-10-2018 MB46_16005 ce23af234ebb4821a7570a81046f76bc 482 PRINTS PR00419 Adrenodoxin reductase family signature 26 39 1.4E-5 T 14-10-2018 MB46_16005 ce23af234ebb4821a7570a81046f76bc 482 Gene3D G3DSA:3.90.660.50 205 399 1.5E-8 T 14-10-2018 MB46_16005 ce23af234ebb4821a7570a81046f76bc 482 Gene3D G3DSA:3.50.50.60 209 282 1.5E-8 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_16005 ce23af234ebb4821a7570a81046f76bc 482 Pfam PF01593 Flavin containing amine oxidoreductase 13 453 2.6E-10 T 14-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 MB46_16005 ce23af234ebb4821a7570a81046f76bc 482 Gene3D G3DSA:3.50.50.60 1 75 4.5E-12 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_16005 ce23af234ebb4821a7570a81046f76bc 482 SUPERFAMILY SSF51905 1 470 1.94E-32 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_18425 cd88019ff1bb1495aa43225896e24cae 939 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 156 169 5.2E-61 T 14-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 MB46_18425 cd88019ff1bb1495aa43225896e24cae 939 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 586 606 5.2E-61 T 14-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 MB46_18425 cd88019ff1bb1495aa43225896e24cae 939 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 420 440 5.2E-61 T 14-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 MB46_18425 cd88019ff1bb1495aa43225896e24cae 939 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 628 657 5.2E-61 T 14-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 MB46_18425 cd88019ff1bb1495aa43225896e24cae 939 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 765 791 5.2E-61 T 14-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 MB46_18425 cd88019ff1bb1495aa43225896e24cae 939 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 207 223 5.2E-61 T 14-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 MB46_18425 cd88019ff1bb1495aa43225896e24cae 939 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 265 280 5.2E-61 T 14-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 MB46_18425 cd88019ff1bb1495aa43225896e24cae 939 Hamap MF_00595 Phosphoenolpyruvate carboxylase [ppc]. 15 939 18.066 T 14-10-2018 IPR022805 Phosphoenolpyruvate carboxylase, bacterial/plant-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 MB46_18425 cd88019ff1bb1495aa43225896e24cae 939 SUPERFAMILY SSF51621 24 939 5.18E-274 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 MB46_18425 cd88019ff1bb1495aa43225896e24cae 939 Gene3D G3DSA:1.20.1440.90 295 423 1.4E-7 T 14-10-2018 MB46_18425 cd88019ff1bb1495aa43225896e24cae 939 ProSitePatterns PS00781 Phosphoenolpyruvate carboxylase active site 1. 157 168 - T 14-10-2018 IPR018129 Phosphoenolpyruvate carboxylase, Lys active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 MB46_18425 cd88019ff1bb1495aa43225896e24cae 939 Pfam PF00311 Phosphoenolpyruvate carboxylase 151 939 3.8E-285 T 14-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 MB46_03685 0b2b96d413a0a4a1d6c0e457b00c16fe 297 SUPERFAMILY SSF55729 196 293 3.3E-11 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase MB46_03685 0b2b96d413a0a4a1d6c0e457b00c16fe 297 Pfam PF00583 Acetyltransferase (GNAT) family 231 286 1.3E-5 T 14-10-2018 IPR000182 GNAT domain MB46_03685 0b2b96d413a0a4a1d6c0e457b00c16fe 297 Pfam PF13312 Domain of unknown function (DUF4081) 67 167 6.7E-22 T 14-10-2018 IPR025289 Domain of unknown function DUF4081 MB46_03685 0b2b96d413a0a4a1d6c0e457b00c16fe 297 Gene3D G3DSA:3.40.630.30 54 295 7.9E-14 T 14-10-2018 MB46_12670 0556833c88c0f8ea599468a2904f7901 81 PIRSF PIRSF006488 5 81 4.7E-21 T 14-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 MB46_12670 0556833c88c0f8ea599468a2904f7901 81 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 17 58 7.0E-13 T 14-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 MB46_12670 0556833c88c0f8ea599468a2904f7901 81 Pfam PF02609 Exonuclease VII small subunit 18 67 1.1E-16 T 14-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 MB46_12670 0556833c88c0f8ea599468a2904f7901 81 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 17 69 4.2E-20 T 14-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 MB46_12670 0556833c88c0f8ea599468a2904f7901 81 SUPERFAMILY SSF116842 11 70 1.7E-16 T 14-10-2018 MB46_12670 0556833c88c0f8ea599468a2904f7901 81 Gene3D G3DSA:1.10.287.1040 12 81 1.0E-13 T 14-10-2018 IPR037004 Exonuclease VII, small subunit superfamily GO:0006308|GO:0008855|GO:0009318 MB46_12670 0556833c88c0f8ea599468a2904f7901 81 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 17 77 13.525 T 14-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 MB46_10840 70c6fcc582859bf70c2d36f04acb3d3e 486 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 353 362 - T 14-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 MB46_10840 70c6fcc582859bf70c2d36f04acb3d3e 486 Gene3D G3DSA:2.40.10.170 14 93 5.0E-26 T 14-10-2018 MB46_10840 70c6fcc582859bf70c2d36f04acb3d3e 486 SUPERFAMILY SSF47917 365 480 2.62E-45 T 14-10-2018 MB46_10840 70c6fcc582859bf70c2d36f04acb3d3e 486 SUPERFAMILY SSF52540 95 367 1.0E-87 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_10840 70c6fcc582859bf70c2d36f04acb3d3e 486 SUPERFAMILY SSF50615 17 93 1.02E-22 T 14-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 MB46_10840 70c6fcc582859bf70c2d36f04acb3d3e 486 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 17 475 5.0E-233 T 14-10-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 MB46_10840 70c6fcc582859bf70c2d36f04acb3d3e 486 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 20 91 2.4E-16 T 14-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 MB46_10840 70c6fcc582859bf70c2d36f04acb3d3e 486 Gene3D G3DSA:1.10.1140.10 365 485 6.2E-46 T 14-10-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 MB46_10840 70c6fcc582859bf70c2d36f04acb3d3e 486 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 149 362 4.3E-63 T 14-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 MB46_10840 70c6fcc582859bf70c2d36f04acb3d3e 486 Gene3D G3DSA:3.40.50.300 94 364 1.5E-103 T 14-10-2018 MB46_10840 70c6fcc582859bf70c2d36f04acb3d3e 486 SMART SM00382 161 424 9.2E-6 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_10840 70c6fcc582859bf70c2d36f04acb3d3e 486 Hamap MF_01347 ATP synthase subunit beta [atpB]. 15 480 53.401 T 14-10-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 MB46_01010 1c52165324fee7db9a102c785dcbb95e 775 TIGRFAM TIGR01701 Fdhalpha-like: oxidoreductase alpha (molybdopterin) subunit 24 773 3.8E-279 T 14-10-2018 IPR010046 Oxidoreductase alpha (molybdopterin) subunit GO:0008863|GO:0030151|GO:0051539 MB46_01010 1c52165324fee7db9a102c785dcbb95e 775 SUPERFAMILY SSF53706 59 651 6.67E-133 T 14-10-2018 MB46_01010 1c52165324fee7db9a102c785dcbb95e 775 Pfam PF00384 Molybdopterin oxidoreductase 120 496 8.1E-25 T 14-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MB46_01010 1c52165324fee7db9a102c785dcbb95e 775 Pfam PF01568 Molydopterin dinucleotide binding domain 660 767 2.0E-9 T 14-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 MB46_01010 1c52165324fee7db9a102c785dcbb95e 775 Gene3D G3DSA:3.40.228.10 196 422 1.2E-65 T 14-10-2018 MB46_01010 1c52165324fee7db9a102c785dcbb95e 775 PIRSF PIRSF000144 4 775 0.0 T 14-10-2018 MB46_01010 1c52165324fee7db9a102c785dcbb95e 775 Gene3D G3DSA:3.40.50.740 132 527 1.2E-65 T 14-10-2018 MB46_01010 1c52165324fee7db9a102c785dcbb95e 775 SUPERFAMILY SSF50692 656 774 7.91E-16 T 14-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily MB46_17750 91b9beb8f7962619d3886e5e63ac8b28 237 Hamap MF_01131 Redox-sensing transcriptional repressor Rex [rex]. 18 226 32.757 T 14-10-2018 IPR022876 Redox-sensing transcriptional repressor Rex GO:0005737|GO:0045892|GO:0051775 MB46_17750 91b9beb8f7962619d3886e5e63ac8b28 237 SUPERFAMILY SSF51735 100 221 1.02E-25 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_17750 91b9beb8f7962619d3886e5e63ac8b28 237 SMART SM00881 97 197 4.0E-10 T 14-10-2018 IPR003781 CoA-binding GO:0048037 MB46_17750 91b9beb8f7962619d3886e5e63ac8b28 237 Pfam PF06971 Putative DNA-binding protein N-terminus 23 70 4.9E-17 T 14-10-2018 IPR009718 Rex DNA-binding, C-terminal domain GO:0005737|GO:0045892|GO:0051775 MB46_17750 91b9beb8f7962619d3886e5e63ac8b28 237 Pfam PF02629 CoA binding domain 99 196 2.4E-16 T 14-10-2018 IPR003781 CoA-binding GO:0048037 MB46_17750 91b9beb8f7962619d3886e5e63ac8b28 237 SUPERFAMILY SSF46785 24 96 1.9E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_17750 91b9beb8f7962619d3886e5e63ac8b28 237 Gene3D G3DSA:1.10.10.10 22 93 4.6E-26 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_17750 91b9beb8f7962619d3886e5e63ac8b28 237 Gene3D G3DSA:3.40.50.720 94 225 2.1E-41 T 14-10-2018 MB46_15600 7c26cb41c4a7ef1c329221c0f49902f8 495 Gene3D G3DSA:1.20.1250.20 11 495 7.1E-124 T 14-10-2018 MB46_15600 7c26cb41c4a7ef1c329221c0f49902f8 495 SUPERFAMILY SSF103473 17 487 3.66E-33 T 14-10-2018 IPR036259 MFS transporter superfamily MB46_15600 7c26cb41c4a7ef1c329221c0f49902f8 495 ProSitePatterns PS01023 PTR2 family proton/oligopeptide symporters signature 2. 165 177 - T 14-10-2018 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 MB46_15600 7c26cb41c4a7ef1c329221c0f49902f8 495 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 24 491 4.2E-143 T 14-10-2018 IPR005279 Dipeptide/tripeptide permease GO:0015833|GO:0016020|GO:1904680 MB46_15600 7c26cb41c4a7ef1c329221c0f49902f8 495 Pfam PF00854 POT family 103 459 2.8E-54 T 14-10-2018 IPR000109 Proton-dependent oligopeptide transporter family GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-427975 MB46_04700 2ebfeee2105e21efe970049c6f73c193 465 Pfam PF01546 Peptidase family M20/M25/M40 97 454 5.1E-28 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 MB46_04700 2ebfeee2105e21efe970049c6f73c193 465 Gene3D G3DSA:3.30.70.360 218 378 9.1E-116 T 14-10-2018 MB46_04700 2ebfeee2105e21efe970049c6f73c193 465 Pfam PF07687 Peptidase dimerisation domain 210 357 6.6E-16 T 14-10-2018 IPR011650 Peptidase M20, dimerisation domain MB46_04700 2ebfeee2105e21efe970049c6f73c193 465 SUPERFAMILY SSF53187 13 457 3.77E-50 T 14-10-2018 MB46_04700 2ebfeee2105e21efe970049c6f73c193 465 Gene3D G3DSA:3.40.630.10 27 449 9.1E-116 T 14-10-2018 MB46_14420 259e91ee522a6416e0261860f51c4181 396 Pfam PF00970 Oxidoreductase FAD-binding domain 18 124 5.5E-8 T 14-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 MB46_14420 259e91ee522a6416e0261860f51c4181 396 TIGRFAM TIGR02160 PA_CoA_Oxy5: phenylacetate-CoA oxygenase/reductase, PaaK subunit 15 395 1.9E-142 T 14-10-2018 IPR011884 Phenylacetate-CoA oxygenase/reductase, PaaK subunit GO:0010124 MB46_14420 259e91ee522a6416e0261860f51c4181 396 SUPERFAMILY SSF54292 270 390 6.87E-25 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 MB46_14420 259e91ee522a6416e0261860f51c4181 396 PRINTS PR00406 Cytochrome B5 reductase signature 152 171 3.7E-5 T 14-10-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 MB46_14420 259e91ee522a6416e0261860f51c4181 396 PRINTS PR00406 Cytochrome B5 reductase signature 112 126 3.7E-5 T 14-10-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 MB46_14420 259e91ee522a6416e0261860f51c4181 396 PRINTS PR00406 Cytochrome B5 reductase signature 189 200 3.7E-5 T 14-10-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 MB46_14420 259e91ee522a6416e0261860f51c4181 396 Gene3D G3DSA:2.40.30.10 13 125 8.3E-20 T 14-10-2018 MB46_14420 259e91ee522a6416e0261860f51c4181 396 SUPERFAMILY SSF52343 147 281 6.94E-30 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain MB46_14420 259e91ee522a6416e0261860f51c4181 396 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 343 351 - T 14-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 MB46_14420 259e91ee522a6416e0261860f51c4181 396 Gene3D G3DSA:3.40.50.80 146 283 3.4E-27 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain MB46_14420 259e91ee522a6416e0261860f51c4181 396 Pfam PF00175 Oxidoreductase NAD-binding domain 154 262 3.3E-14 T 14-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 MB46_14420 259e91ee522a6416e0261860f51c4181 396 Gene3D G3DSA:3.10.20.30 291 396 6.0E-26 T 14-10-2018 IPR012675 Beta-grasp domain superfamily MB46_14420 259e91ee522a6416e0261860f51c4181 396 SUPERFAMILY SSF63380 14 124 1.15E-18 T 14-10-2018 IPR017938 Riboflavin synthase-like beta-barrel MB46_14420 259e91ee522a6416e0261860f51c4181 396 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 325 386 8.3E-13 T 14-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MB46_18520 2fde91c16136ab6cdd4e7a6358643bcc 269 Gene3D G3DSA:1.10.8.50 128 267 9.8E-30 T 14-10-2018 MB46_18520 2fde91c16136ab6cdd4e7a6358643bcc 269 SUPERFAMILY SSF81624 2 128 4.06E-21 T 14-10-2018 IPR035937 MutM-like, N-terminal MB46_18520 2fde91c16136ab6cdd4e7a6358643bcc 269 Gene3D G3DSA:3.20.190.10 2 127 3.6E-18 T 14-10-2018 IPR035937 MutM-like, N-terminal MB46_18520 2fde91c16136ab6cdd4e7a6358643bcc 269 SUPERFAMILY SSF57716 214 267 1.06E-7 T 14-10-2018 MB46_18520 2fde91c16136ab6cdd4e7a6358643bcc 269 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 2 82 1.2E-5 T 14-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 MB46_18520 2fde91c16136ab6cdd4e7a6358643bcc 269 SUPERFAMILY SSF46946 126 191 2.09E-19 T 14-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 MB46_18520 2fde91c16136ab6cdd4e7a6358643bcc 269 SMART SM01232 127 215 1.9E-25 T 14-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 MB46_18520 2fde91c16136ab6cdd4e7a6358643bcc 269 SMART SM00898 2 113 3.6E-18 T 14-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 MB46_18520 2fde91c16136ab6cdd4e7a6358643bcc 269 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 127 186 6.7E-12 T 14-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 MB46_01085 891c0797a9b439cbf8cea53166938be9 300 SUPERFAMILY SSF51735 1 118 1.69E-34 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_01085 891c0797a9b439cbf8cea53166938be9 300 Gene3D G3DSA:3.40.50.261 135 298 3.6E-62 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MB46_01085 891c0797a9b439cbf8cea53166938be9 300 PRINTS PR01798 Succinyl-CoA synthase signature 217 230 2.3E-34 T 14-10-2018 MB46_01085 891c0797a9b439cbf8cea53166938be9 300 PRINTS PR01798 Succinyl-CoA synthase signature 186 204 2.3E-34 T 14-10-2018 MB46_01085 891c0797a9b439cbf8cea53166938be9 300 PRINTS PR01798 Succinyl-CoA synthase signature 249 266 2.3E-34 T 14-10-2018 MB46_01085 891c0797a9b439cbf8cea53166938be9 300 PRINTS PR01798 Succinyl-CoA synthase signature 86 103 2.3E-34 T 14-10-2018 MB46_01085 891c0797a9b439cbf8cea53166938be9 300 Pfam PF02629 CoA binding domain 6 103 2.1E-23 T 14-10-2018 IPR003781 CoA-binding GO:0048037 MB46_01085 891c0797a9b439cbf8cea53166938be9 300 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 163 190 - T 14-10-2018 IPR033847 ATP-citrate lyase/succinyl-CoA ligase, conserved site MB46_01085 891c0797a9b439cbf8cea53166938be9 300 Pfam PF00549 CoA-ligase 178 280 1.1E-14 T 14-10-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MB46_01085 891c0797a9b439cbf8cea53166938be9 300 SMART SM00881 4 104 7.5E-30 T 14-10-2018 IPR003781 CoA-binding GO:0048037 MB46_01085 891c0797a9b439cbf8cea53166938be9 300 SUPERFAMILY SSF52210 134 295 2.09E-47 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MB46_01085 891c0797a9b439cbf8cea53166938be9 300 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 245 258 - T 14-10-2018 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site MB46_01085 891c0797a9b439cbf8cea53166938be9 300 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 3 296 2.3E-125 T 14-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 MB46_01085 891c0797a9b439cbf8cea53166938be9 300 Gene3D G3DSA:3.40.50.720 1 134 8.6E-47 T 14-10-2018 MB46_01085 891c0797a9b439cbf8cea53166938be9 300 PIRSF PIRSF001553 1 300 2.4E-117 T 14-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 MB46_01085 891c0797a9b439cbf8cea53166938be9 300 Hamap MF_01988 Succinate--CoA ligase [ADP-forming] subunit alpha [sucD]. 1 297 39.967 T 14-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 MB46_04065 b1c5daf741540f66c764c19e83947f37 847 SUPERFAMILY SSF46955 433 502 1.65E-14 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily MB46_04065 b1c5daf741540f66c764c19e83947f37 847 Gene3D G3DSA:3.30.56.10 7 202 1.7E-54 T 14-10-2018 MB46_04065 b1c5daf741540f66c764c19e83947f37 847 SUPERFAMILY SSF55681 494 739 8.95E-34 T 14-10-2018 MB46_04065 b1c5daf741540f66c764c19e83947f37 847 Gene3D G3DSA:3.30.930.10 514 742 3.1E-49 T 14-10-2018 MB46_04065 b1c5daf741540f66c764c19e83947f37 847 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 2 847 6.0E-173 T 14-10-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 MB46_04065 b1c5daf741540f66c764c19e83947f37 847 SUPERFAMILY SSF50249 44 212 1.37E-23 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold MB46_04065 b1c5daf741540f66c764c19e83947f37 847 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 841 38.246 T 14-10-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 MB46_04065 b1c5daf741540f66c764c19e83947f37 847 SMART SM00896 754 847 1.6E-38 T 14-10-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 MB46_04065 b1c5daf741540f66c764c19e83947f37 847 Gene3D G3DSA:3.50.40.10 231 424 7.0E-75 T 14-10-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 KEGG: 00970+6.1.1.20 MB46_04065 b1c5daf741540f66c764c19e83947f37 847 Gene3D G3DSA:3.30.56.10 432 502 8.6E-17 T 14-10-2018 MB46_04065 b1c5daf741540f66c764c19e83947f37 847 Pfam PF03484 tRNA synthetase B5 domain 437 498 5.3E-14 T 14-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 MB46_04065 b1c5daf741540f66c764c19e83947f37 847 SMART SM00874 430 498 3.7E-16 T 14-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 MB46_04065 b1c5daf741540f66c764c19e83947f37 847 Pfam PF03483 B3/4 domain 241 414 7.6E-66 T 14-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 MB46_04065 b1c5daf741540f66c764c19e83947f37 847 Gene3D G3DSA:3.30.70.380 755 847 9.3E-25 T 14-10-2018 IPR036690 Ferrodoxin-fold anticodon-binding domain superfamily KEGG: 00970+6.1.1.20 MB46_04065 b1c5daf741540f66c764c19e83947f37 847 Gene3D G3DSA:2.40.50.140 41 176 1.7E-54 T 14-10-2018 MB46_04065 b1c5daf741540f66c764c19e83947f37 847 SUPERFAMILY SSF56037 240 426 1.54E-65 T 14-10-2018 MB46_04065 b1c5daf741540f66c764c19e83947f37 847 Pfam PF01588 Putative tRNA binding domain 48 155 9.7E-6 T 14-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 MB46_04065 b1c5daf741540f66c764c19e83947f37 847 Pfam PF03147 Ferredoxin-fold anticodon binding domain 754 847 2.5E-23 T 14-10-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 MB46_04065 b1c5daf741540f66c764c19e83947f37 847 SMART SM00873 241 414 3.5E-83 T 14-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 MB46_04065 b1c5daf741540f66c764c19e83947f37 847 SUPERFAMILY SSF54991 750 847 9.68E-26 T 14-10-2018 IPR036690 Ferrodoxin-fold anticodon-binding domain superfamily KEGG: 00970+6.1.1.20 MB46_17245 c877f768d0d2c7b2f6dab7b3b3c95ab3 521 Gene3D G3DSA:3.40.50.2020 288 452 1.5E-152 T 14-10-2018 MB46_17245 c877f768d0d2c7b2f6dab7b3b3c95ab3 521 PIRSF PIRSF000485 19 482 2.3E-162 T 14-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 MB46_17245 c877f768d0d2c7b2f6dab7b3b3c95ab3 521 Gene3D G3DSA:3.60.20.10 23 471 1.5E-152 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MB46_17245 c877f768d0d2c7b2f6dab7b3b3c95ab3 521 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 23 470 9.9E-157 T 14-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 MB46_17245 c877f768d0d2c7b2f6dab7b3b3c95ab3 521 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 22 469 45.62 T 14-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 MB46_17245 c877f768d0d2c7b2f6dab7b3b3c95ab3 521 Pfam PF00156 Phosphoribosyl transferase domain 294 399 6.4E-8 T 14-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 MB46_17245 c877f768d0d2c7b2f6dab7b3b3c95ab3 521 Pfam PF13522 Glutamine amidotransferase domain 85 223 1.2E-15 T 14-10-2018 MB46_17245 c877f768d0d2c7b2f6dab7b3b3c95ab3 521 SUPERFAMILY SSF53271 264 477 2.36E-69 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like MB46_17245 c877f768d0d2c7b2f6dab7b3b3c95ab3 521 SUPERFAMILY SSF56235 23 281 1.03E-66 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MB46_17465 3203197e7d1ca7226cb8dc6503f2ff8d 278 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 167 269 4.1E-26 T 14-10-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 MB46_17465 3203197e7d1ca7226cb8dc6503f2ff8d 278 Gene3D G3DSA:1.10.3730.10 169 275 3.4E-31 T 14-10-2018 MB46_17465 3203197e7d1ca7226cb8dc6503f2ff8d 278 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 5 269 3.2E-66 T 14-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 MB46_17465 3203197e7d1ca7226cb8dc6503f2ff8d 278 SUPERFAMILY SSF48179 166 274 3.57E-27 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MB46_17465 3203197e7d1ca7226cb8dc6503f2ff8d 278 PIRSF PIRSF000193 2 274 2.7E-67 T 14-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 MB46_17465 3203197e7d1ca7226cb8dc6503f2ff8d 278 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 4 103 6.3E-20 T 14-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal MB46_17465 3203197e7d1ca7226cb8dc6503f2ff8d 278 SUPERFAMILY SSF51735 3 162 9.7E-32 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_17465 3203197e7d1ca7226cb8dc6503f2ff8d 278 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 3 271 22.991 T 14-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 MB46_17465 3203197e7d1ca7226cb8dc6503f2ff8d 278 Gene3D G3DSA:3.40.50.720 1 168 2.9E-45 T 14-10-2018 MB46_17465 3203197e7d1ca7226cb8dc6503f2ff8d 278 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 227 249 - T 14-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 MB46_02450 5c9616bcdec21858d3d2bd11702ff80b 326 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 13 128 2.1E-41 T 14-10-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 MB46_02450 5c9616bcdec21858d3d2bd11702ff80b 326 Gene3D G3DSA:3.40.50.2020 155 299 2.2E-109 T 14-10-2018 MB46_02450 5c9616bcdec21858d3d2bd11702ff80b 326 Gene3D G3DSA:3.40.50.2020 16 310 2.2E-109 T 14-10-2018 MB46_02450 5c9616bcdec21858d3d2bd11702ff80b 326 Hamap MF_00583_B Putative ribose-phosphate pyrophosphokinase [prs]. 12 323 44.197 T 14-10-2018 IPR037515 Ribose-phosphate pyrophosphokinase, bacterial-type GO:0004749 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 MB46_02450 5c9616bcdec21858d3d2bd11702ff80b 326 Pfam PF14572 Phosphoribosyl synthetase-associated domain 213 322 2.7E-20 T 14-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 MB46_02450 5c9616bcdec21858d3d2bd11702ff80b 326 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 136 151 - T 14-10-2018 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 MB46_02450 5c9616bcdec21858d3d2bd11702ff80b 326 SUPERFAMILY SSF53271 77 314 4.64E-58 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like MB46_02450 5c9616bcdec21858d3d2bd11702ff80b 326 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 14 323 3.1E-112 T 14-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 MB46_02450 5c9616bcdec21858d3d2bd11702ff80b 326 SMART SM01400 12 128 3.6E-63 T 14-10-2018 MB46_18095 1b6dfae52ccdd07d7e8a2415d3d2632a 224 SUPERFAMILY SSF52172 4 127 1.38E-39 T 14-10-2018 IPR011006 CheY-like superfamily MB46_18095 1b6dfae52ccdd07d7e8a2415d3d2632a 224 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 221 4.6E-24 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MB46_18095 1b6dfae52ccdd07d7e8a2415d3d2632a 224 Pfam PF00072 Response regulator receiver domain 7 116 2.0E-30 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MB46_18095 1b6dfae52ccdd07d7e8a2415d3d2632a 224 SMART SM00448 5 116 1.4E-38 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MB46_18095 1b6dfae52ccdd07d7e8a2415d3d2632a 224 Gene3D G3DSA:1.10.10.10 131 224 3.2E-28 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_18095 1b6dfae52ccdd07d7e8a2415d3d2632a 224 Gene3D G3DSA:3.40.50.2300 2 123 3.7E-36 T 14-10-2018 MB46_18095 1b6dfae52ccdd07d7e8a2415d3d2632a 224 SMART SM00862 145 221 2.1E-25 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MB46_18095 1b6dfae52ccdd07d7e8a2415d3d2632a 224 SUPERFAMILY SSF46894 132 221 7.75E-26 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MB46_00165 99b1989f18f27b691ca241f7e9a85a0d 361 SMART SM00382 51 246 8.5E-20 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_00165 99b1989f18f27b691ca241f7e9a85a0d 361 SUPERFAMILY SSF52540 19 267 4.57E-70 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_00165 99b1989f18f27b691ca241f7e9a85a0d 361 Pfam PF00005 ABC transporter 42 197 6.1E-34 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_00165 99b1989f18f27b691ca241f7e9a85a0d 361 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 248 287 5.1E-8 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MB46_00165 99b1989f18f27b691ca241f7e9a85a0d 361 Gene3D G3DSA:3.40.50.300 17 338 5.9E-87 T 14-10-2018 MB46_00165 99b1989f18f27b691ca241f7e9a85a0d 361 ProSitePatterns PS00211 ABC transporters family signature. 169 183 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_10145 4e9eef027f92c30b468112b274edb1ad 372 SUPERFAMILY SSF53335 187 371 8.52E-37 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MB46_10145 4e9eef027f92c30b468112b274edb1ad 372 Pfam PF13847 Methyltransferase domain 190 309 5.8E-22 T 14-10-2018 IPR025714 Methyltransferase domain MB46_10145 4e9eef027f92c30b468112b274edb1ad 372 Gene3D G3DSA:3.40.50.150 176 349 8.0E-36 T 14-10-2018 MB46_10920 f4141d3567e77724324083a48e2326e8 297 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 15 296 35.439 T 14-10-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 MB46_10920 f4141d3567e77724324083a48e2326e8 297 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 23 296 4.1E-47 T 14-10-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 MB46_10920 f4141d3567e77724324083a48e2326e8 297 Gene3D G3DSA:1.10.8.10 14 95 4.4E-18 T 14-10-2018 MB46_10920 f4141d3567e77724324083a48e2326e8 297 Gene3D G3DSA:3.40.50.150 96 297 2.1E-46 T 14-10-2018 MB46_10920 f4141d3567e77724324083a48e2326e8 297 Pfam PF05175 Methyltransferase small domain 130 212 1.5E-11 T 14-10-2018 IPR007848 Methyltransferase small domain GO:0008168 MB46_10920 f4141d3567e77724324083a48e2326e8 297 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 37 292 1.0E-64 T 14-10-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 MB46_10920 f4141d3567e77724324083a48e2326e8 297 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 199 205 - T 14-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 MB46_10920 f4141d3567e77724324083a48e2326e8 297 SUPERFAMILY SSF53335 17 291 2.46E-42 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MB46_00745 6d8b5dc32cafc66df709796dc8030d8b 297 SMART SM00382 47 250 3.5E-18 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_00745 6d8b5dc32cafc66df709796dc8030d8b 297 ProSitePatterns PS00211 ABC transporters family signature. 173 187 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_00745 6d8b5dc32cafc66df709796dc8030d8b 297 Gene3D G3DSA:3.40.50.300 18 294 2.7E-78 T 14-10-2018 MB46_00745 6d8b5dc32cafc66df709796dc8030d8b 297 SUPERFAMILY SSF52540 19 272 8.37E-60 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_00745 6d8b5dc32cafc66df709796dc8030d8b 297 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 252 284 2.8E-6 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MB46_00745 6d8b5dc32cafc66df709796dc8030d8b 297 Pfam PF00005 ABC transporter 38 200 9.5E-25 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_06200 a14f715fbdb50b74feffdbdb7c4ab82f 241 SUPERFAMILY SSF53167 1 227 6.41E-40 T 14-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 MB46_06200 a14f715fbdb50b74feffdbdb7c4ab82f 241 TIGRFAM TIGR01704 MTA/SAH-Nsdase: MTA/SAH nucleosidase 19 227 8.6E-39 T 14-10-2018 IPR010049 MTA/SAH nucleosidase GO:0008782|GO:0008930|GO:0009164|GO:0019509 KEGG: 00270+3.2.2.9|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 MB46_06200 a14f715fbdb50b74feffdbdb7c4ab82f 241 Gene3D G3DSA:3.40.50.1580 1 235 1.5E-43 T 14-10-2018 MB46_06200 a14f715fbdb50b74feffdbdb7c4ab82f 241 Pfam PF01048 Phosphorylase superfamily 21 228 2.9E-27 T 14-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 MB46_07995 4965de05d712cfb970b9fec568336dec 125 Pfam PF03965 Penicillinase repressor 4 123 1.1E-20 T 14-10-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 MB46_07995 4965de05d712cfb970b9fec568336dec 125 SUPERFAMILY SSF46785 2 124 6.04E-24 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_07995 4965de05d712cfb970b9fec568336dec 125 Gene3D G3DSA:1.10.10.10 1 79 4.9E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_18350 a37e36f24519a0329dbdce824b46c544 273 Pfam PF06445 GyrI-like small molecule binding domain 119 269 3.4E-10 T 14-10-2018 IPR029442 GyrI-like small molecule binding domain MB46_18350 a37e36f24519a0329dbdce824b46c544 273 SMART SM00871 118 270 1.1E-16 T 14-10-2018 IPR010499 Bacterial transcription activator, effector binding MB46_18350 a37e36f24519a0329dbdce824b46c544 273 SUPERFAMILY SSF46955 2 113 8.06E-23 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily MB46_18350 a37e36f24519a0329dbdce824b46c544 273 Pfam PF13411 MerR HTH family regulatory protein 4 70 6.1E-12 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MB46_18350 a37e36f24519a0329dbdce824b46c544 273 Gene3D G3DSA:1.10.1660.10 1 110 1.2E-22 T 14-10-2018 MB46_18350 a37e36f24519a0329dbdce824b46c544 273 SUPERFAMILY SSF55136 119 269 2.88E-17 T 14-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily MB46_18350 a37e36f24519a0329dbdce824b46c544 273 SMART SM00422 2 71 8.9E-15 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MB46_18350 a37e36f24519a0329dbdce824b46c544 273 Gene3D G3DSA:3.20.80.10 112 270 3.8E-29 T 14-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily MB46_10890 c4793ffd6cbd7e365e66c656735d5316 627 Pfam PF13727 CoA-binding domain 96 257 5.5E-8 T 14-10-2018 MB46_10890 c4793ffd6cbd7e365e66c656735d5316 627 SUPERFAMILY SSF51735 305 565 2.23E-61 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_10890 c4793ffd6cbd7e365e66c656735d5316 627 Gene3D G3DSA:3.40.50.720 303 598 2.7E-104 T 14-10-2018 MB46_10890 c4793ffd6cbd7e365e66c656735d5316 627 Pfam PF02719 Polysaccharide biosynthesis protein 308 585 6.9E-103 T 14-10-2018 IPR003869 Polysaccharide biosynthesis protein, CapD-like domain MB46_10890 c4793ffd6cbd7e365e66c656735d5316 627 Gene3D G3DSA:3.40.50.720 157 289 7.1E-26 T 14-10-2018 MB46_10890 c4793ffd6cbd7e365e66c656735d5316 627 SUPERFAMILY SSF51735 161 293 1.34E-9 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_18275 e27c95505873df422ba692ef50b72c16 548 SUPERFAMILY SSF51645 13 536 4.58E-180 T 14-10-2018 IPR011076 Malate synthase-like superfamily GO:0003824 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 MB46_18275 e27c95505873df422ba692ef50b72c16 548 ProSitePatterns PS00510 Malate synthase signature. 273 288 - T 14-10-2018 IPR019830 Malate synthase, conserved site GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 MB46_18275 e27c95505873df422ba692ef50b72c16 548 TIGRFAM TIGR01344 malate_syn_A: malate synthase A 28 534 4.0E-229 T 14-10-2018 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 MB46_18275 e27c95505873df422ba692ef50b72c16 548 Gene3D G3DSA:3.20.20.360 11 419 2.8E-183 T 14-10-2018 MB46_18275 e27c95505873df422ba692ef50b72c16 548 PIRSF PIRSF001363 8 538 1.1E-236 T 14-10-2018 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 MB46_18275 e27c95505873df422ba692ef50b72c16 548 Pfam PF01274 Malate synthase 22 534 2.2E-197 T 14-10-2018 IPR001465 Malate synthase GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 MB46_18275 e27c95505873df422ba692ef50b72c16 548 Gene3D G3DSA:1.20.1220.12 422 536 8.4E-43 T 14-10-2018 MB46_04810 993a29579711320386d80bf1b147eb18 229 SUPERFAMILY SSF56281 15 225 2.44E-33 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MB46_04810 993a29579711320386d80bf1b147eb18 229 SMART SM00849 25 208 5.7E-21 T 14-10-2018 IPR001279 Metallo-beta-lactamase MB46_04810 993a29579711320386d80bf1b147eb18 229 Gene3D G3DSA:3.60.15.10 12 227 1.6E-40 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MB46_04810 993a29579711320386d80bf1b147eb18 229 Pfam PF00753 Metallo-beta-lactamase superfamily 26 208 1.0E-9 T 14-10-2018 IPR001279 Metallo-beta-lactamase MB46_09170 e1c2fa3f797e481bd3dbc034d92e90a2 558 Pfam PF00144 Beta-lactamase 76 407 8.8E-53 T 14-10-2018 IPR001466 Beta-lactamase-related MB46_09170 e1c2fa3f797e481bd3dbc034d92e90a2 558 Gene3D G3DSA:2.40.128.600 441 556 1.7E-23 T 14-10-2018 MB46_09170 e1c2fa3f797e481bd3dbc034d92e90a2 558 SUPERFAMILY SSF56601 69 416 1.43E-66 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like MB46_09170 e1c2fa3f797e481bd3dbc034d92e90a2 558 Gene3D G3DSA:3.40.710.10 73 417 4.1E-70 T 14-10-2018 MB46_09170 e1c2fa3f797e481bd3dbc034d92e90a2 558 Pfam PF11954 Domain of unknown function (DUF3471) 451 536 3.2E-8 T 14-10-2018 IPR021860 Peptidase S12, Pab87-related, C-terminal MB46_02390 7eb282ebbc88e0357520b375ee0fa9e6 498 Gene3D G3DSA:3.40.309.10 273 462 3.0E-171 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 MB46_02390 7eb282ebbc88e0357520b375ee0fa9e6 498 SUPERFAMILY SSF53720 19 492 2.23E-163 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 MB46_02390 7eb282ebbc88e0357520b375ee0fa9e6 498 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 294 305 - T 14-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 MB46_02390 7eb282ebbc88e0357520b375ee0fa9e6 498 Pfam PF00171 Aldehyde dehydrogenase family 30 488 1.4E-161 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 MB46_02390 7eb282ebbc88e0357520b375ee0fa9e6 498 Gene3D G3DSA:3.40.605.10 30 484 3.0E-171 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 MB46_02390 7eb282ebbc88e0357520b375ee0fa9e6 498 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 266 273 - T 14-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 MB46_10050 d8535ab81699ea021012c8e716b42e1b 472 SUPERFAMILY SSF103473 29 467 6.93E-39 T 14-10-2018 IPR036259 MFS transporter superfamily MB46_10050 d8535ab81699ea021012c8e716b42e1b 472 Gene3D G3DSA:1.20.1250.20 30 210 2.0E-25 T 14-10-2018 MB46_10050 d8535ab81699ea021012c8e716b42e1b 472 Gene3D G3DSA:1.20.1250.20 283 471 2.3E-8 T 14-10-2018 MB46_10050 d8535ab81699ea021012c8e716b42e1b 472 Pfam PF07690 Major Facilitator Superfamily 34 427 1.9E-29 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MB46_15360 2e5f306da26d3fa24d426d4364b0442f 469 TIGRFAM TIGR00416 sms: DNA repair protein RadA 11 454 9.4E-149 T 14-10-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 MB46_15360 2e5f306da26d3fa24d426d4364b0442f 469 SUPERFAMILY SSF52540 75 298 2.24E-44 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_15360 2e5f306da26d3fa24d426d4364b0442f 469 Gene3D G3DSA:3.40.50.300 66 285 6.8E-39 T 14-10-2018 MB46_15360 2e5f306da26d3fa24d426d4364b0442f 469 Gene3D G3DSA:3.30.230.10 332 462 1.1E-14 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MB46_15360 2e5f306da26d3fa24d426d4364b0442f 469 Pfam PF13481 AAA domain 77 227 1.4E-17 T 14-10-2018 MB46_15360 2e5f306da26d3fa24d426d4364b0442f 469 SUPERFAMILY SSF54211 260 461 6.07E-33 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MB46_15360 2e5f306da26d3fa24d426d4364b0442f 469 SMART SM00382 90 249 2.2E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_15360 2e5f306da26d3fa24d426d4364b0442f 469 Hamap MF_01498 DNA repair protein RadA [radA]. 27 461 40.613 T 14-10-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 MB46_15360 2e5f306da26d3fa24d426d4364b0442f 469 Pfam PF13541 Subunit ChlI of Mg-chelatase 373 433 5.6E-9 T 14-10-2018 MB46_15360 2e5f306da26d3fa24d426d4364b0442f 469 PRINTS PR01874 DNA repair protein radA signature 82 110 9.5E-73 T 14-10-2018 MB46_15360 2e5f306da26d3fa24d426d4364b0442f 469 PRINTS PR01874 DNA repair protein radA signature 218 246 9.5E-73 T 14-10-2018 MB46_15360 2e5f306da26d3fa24d426d4364b0442f 469 PRINTS PR01874 DNA repair protein radA signature 16 40 9.5E-73 T 14-10-2018 MB46_15360 2e5f306da26d3fa24d426d4364b0442f 469 PRINTS PR01874 DNA repair protein radA signature 179 203 9.5E-73 T 14-10-2018 MB46_15360 2e5f306da26d3fa24d426d4364b0442f 469 PRINTS PR01874 DNA repair protein radA signature 253 279 9.5E-73 T 14-10-2018 MB46_15360 2e5f306da26d3fa24d426d4364b0442f 469 PRINTS PR01874 DNA repair protein radA signature 327 350 9.5E-73 T 14-10-2018 MB46_03270 1785e81410b211407aa143fdeee88433 452 Gene3D G3DSA:1.10.357.20 275 450 2.7E-51 T 14-10-2018 IPR038048 Magnesium transporter MgtE, transmembrane domain MB46_03270 1785e81410b211407aa143fdeee88433 452 SUPERFAMILY SSF161093 280 450 3.27E-45 T 14-10-2018 IPR036739 SLC41 divalent cation transporters, integral membrane domain superfamily GO:0006812|GO:0008324 MB46_03270 1785e81410b211407aa143fdeee88433 452 TIGRFAM TIGR00400 mgtE: magnesium transporter 27 451 6.2E-107 T 14-10-2018 IPR006669 Magnesium transporter MgtE GO:0015095|GO:0015693|GO:0016020 MB46_03270 1785e81410b211407aa143fdeee88433 452 SMART SM00924 35 138 1.6E-21 T 14-10-2018 IPR006668 Magnesium transporter, MgtE intracellular domain MB46_03270 1785e81410b211407aa143fdeee88433 452 SMART SM00116 145 198 0.0028 T 14-10-2018 IPR000644 CBS domain MB46_03270 1785e81410b211407aa143fdeee88433 452 SMART SM00116 208 256 0.0079 T 14-10-2018 IPR000644 CBS domain MB46_03270 1785e81410b211407aa143fdeee88433 452 Gene3D G3DSA:3.10.580.10 135 260 3.2E-33 T 14-10-2018 MB46_03270 1785e81410b211407aa143fdeee88433 452 SUPERFAMILY SSF158791 11 134 9.68E-22 T 14-10-2018 MB46_03270 1785e81410b211407aa143fdeee88433 452 Pfam PF01769 Divalent cation transporter 323 444 4.5E-26 T 14-10-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 MB46_03270 1785e81410b211407aa143fdeee88433 452 SUPERFAMILY SSF54631 138 273 7.2E-28 T 14-10-2018 MB46_03270 1785e81410b211407aa143fdeee88433 452 Gene3D G3DSA:1.25.60.10 10 133 4.0E-16 T 14-10-2018 IPR038076 MgtE, N-terminal domain superfamily MB46_03270 1785e81410b211407aa143fdeee88433 452 Pfam PF03448 MgtE intracellular N domain 37 135 1.5E-19 T 14-10-2018 IPR006668 Magnesium transporter, MgtE intracellular domain MB46_03270 1785e81410b211407aa143fdeee88433 452 Pfam PF00571 CBS domain 138 197 2.1E-8 T 14-10-2018 IPR000644 CBS domain MB46_03270 1785e81410b211407aa143fdeee88433 452 Pfam PF00571 CBS domain 203 255 6.2E-6 T 14-10-2018 IPR000644 CBS domain MB46_11375 7a78229f362b60fba8541879206be1c2 669 Pfam PF01757 Acyltransferase family 3 329 4.6E-14 T 14-10-2018 IPR002656 Acyltransferase 3 GO:0016747 MB46_16295 ebb618c0f7d193fc19191e856b28b65d 101 TIGRFAM TIGR00166 S6: ribosomal protein bS6 1 92 3.5E-24 T 14-10-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_16295 ebb618c0f7d193fc19191e856b28b65d 101 SUPERFAMILY SSF54995 1 96 5.36E-33 T 14-10-2018 IPR035980 Ribosomal protein S6 superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_16295 ebb618c0f7d193fc19191e856b28b65d 101 Gene3D G3DSA:3.30.70.60 1 100 1.1E-31 T 14-10-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 MB46_16295 ebb618c0f7d193fc19191e856b28b65d 101 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 95 21.089 T 14-10-2018 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 MB46_16295 ebb618c0f7d193fc19191e856b28b65d 101 Pfam PF01250 Ribosomal protein S6 4 92 1.2E-28 T 14-10-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_15135 c814fb794b998e001fc29dca33351612 435 Pfam PF04030 D-arabinono-1,4-lactone oxidase 174 433 1.0E-65 T 14-10-2018 IPR007173 D-arabinono-1,4-lactone oxidase GO:0003885|GO:0016020|GO:0055114 MB46_15135 c814fb794b998e001fc29dca33351612 435 PIRSF PIRSF000136 1 435 1.9E-117 T 14-10-2018 IPR010031 L-gulonolactone/D-arabinono-1,4-lactone oxidase GO:0016899|GO:0055114 MB46_15135 c814fb794b998e001fc29dca33351612 435 Gene3D G3DSA:3.30.465.10 69 193 2.1E-38 T 14-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 MB46_15135 c814fb794b998e001fc29dca33351612 435 SUPERFAMILY SSF56176 3 179 1.47E-45 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 MB46_15135 c814fb794b998e001fc29dca33351612 435 TIGRFAM TIGR01679 bact_FAD_ox: FAD-linked oxidoreductase 4 434 4.3E-120 T 14-10-2018 MB46_15135 c814fb794b998e001fc29dca33351612 435 Gene3D G3DSA:3.30.43.10 1 67 4.0E-20 T 14-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 MB46_15135 c814fb794b998e001fc29dca33351612 435 Gene3D G3DSA:3.30.70.2520 305 397 3.1E-21 T 14-10-2018 MB46_15135 c814fb794b998e001fc29dca33351612 435 Pfam PF01565 FAD binding domain 15 150 1.3E-25 T 14-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 MB46_18220 297a0710ee857f1a093540f8ef1e478a 244 SUPERFAMILY SSF51658 5 240 1.31E-35 T 14-10-2018 IPR036237 Xylose isomerase-like superfamily MB46_18220 297a0710ee857f1a093540f8ef1e478a 244 Pfam PF01261 Xylose isomerase-like TIM barrel 27 187 7.0E-18 T 14-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain MB46_18220 297a0710ee857f1a093540f8ef1e478a 244 Gene3D G3DSA:3.20.20.150 1 242 7.4E-57 T 14-10-2018 MB46_04970 7432bec2f907521be1a806ac2c5f1156 694 Pfam PF02151 UvrB/uvrC motif 650 683 9.7E-9 T 14-10-2018 IPR001943 UVR domain GO:0005515 MB46_04970 7432bec2f907521be1a806ac2c5f1156 694 Gene3D G3DSA:3.40.50.300 274 421 3.9E-53 T 14-10-2018 MB46_04970 7432bec2f907521be1a806ac2c5f1156 694 SMART SM00490 467 553 1.1E-16 T 14-10-2018 IPR001650 Helicase, C-terminal MB46_04970 7432bec2f907521be1a806ac2c5f1156 694 Gene3D G3DSA:3.40.50.300 5 251 4.5E-73 T 14-10-2018 MB46_04970 7432bec2f907521be1a806ac2c5f1156 694 SUPERFAMILY SSF46600 645 687 3.4E-9 T 14-10-2018 IPR036876 UVR domain superfamily MB46_04970 7432bec2f907521be1a806ac2c5f1156 694 Pfam PF12344 Ultra-violet resistance protein B 559 600 1.2E-21 T 14-10-2018 IPR024759 UvrB, YAD/RRR-motif-containing domain MB46_04970 7432bec2f907521be1a806ac2c5f1156 694 Hamap MF_00204 UvrABC system protein B [uvrB]. 12 684 42.222 T 14-10-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006289|GO:0009380|GO:0016887 MB46_04970 7432bec2f907521be1a806ac2c5f1156 694 Pfam PF04851 Type III restriction enzyme, res subunit 20 128 2.9E-10 T 14-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 MB46_04970 7432bec2f907521be1a806ac2c5f1156 694 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 14 682 0.0 T 14-10-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006289|GO:0009380|GO:0016887 MB46_04970 7432bec2f907521be1a806ac2c5f1156 694 Gene3D G3DSA:3.40.50.300 422 603 1.1E-47 T 14-10-2018 MB46_04970 7432bec2f907521be1a806ac2c5f1156 694 SMART SM00487 18 433 8.3E-24 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MB46_04970 7432bec2f907521be1a806ac2c5f1156 694 Pfam PF00271 Helicase conserved C-terminal domain 440 551 1.6E-16 T 14-10-2018 IPR001650 Helicase, C-terminal MB46_04970 7432bec2f907521be1a806ac2c5f1156 694 SUPERFAMILY SSF52540 41 600 1.99E-33 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_04970 7432bec2f907521be1a806ac2c5f1156 694 SUPERFAMILY SSF52540 13 422 1.22E-133 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_04970 7432bec2f907521be1a806ac2c5f1156 694 Gene3D G3DSA:4.10.860.10 633 686 2.1E-5 T 14-10-2018 MB46_16010 38d7dd77b5290cecdbf39125e9f8af2b 502 Pfam PF09594 Glycosyltransferase family 87 144 355 1.9E-6 T 14-10-2018 IPR018584 Glycosyltransferase family 87 GO:0016758 MB46_02060 f4d461f06a37ce00e368eba457f85cfa 270 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 14-10-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 MB46_02060 f4d461f06a37ce00e368eba457f85cfa 270 Gene3D G3DSA:1.10.10.10 1 56 3.2E-8 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_02060 f4d461f06a37ce00e368eba457f85cfa 270 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 3.0E-8 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MB46_02060 f4d461f06a37ce00e368eba457f85cfa 270 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 3.0E-8 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MB46_02060 f4d461f06a37ce00e368eba457f85cfa 270 SUPERFAMILY SSF46785 5 61 8.84E-13 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_02060 f4d461f06a37ce00e368eba457f85cfa 270 Pfam PF08220 DeoR-like helix-turn-helix domain 6 57 4.9E-16 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MB46_02060 f4d461f06a37ce00e368eba457f85cfa 270 SUPERFAMILY SSF100950 76 240 8.76E-29 T 14-10-2018 IPR037171 NagB/RpiA transferase-like MB46_02060 f4d461f06a37ce00e368eba457f85cfa 270 SMART SM00420 6 58 1.3E-15 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MB46_02060 f4d461f06a37ce00e368eba457f85cfa 270 SMART SM01134 74 241 9.0E-57 T 14-10-2018 MB46_02060 f4d461f06a37ce00e368eba457f85cfa 270 Pfam PF00455 DeoR C terminal sensor domain 77 239 9.3E-44 T 14-10-2018 IPR014036 DeoR C-terminal sensor domain MB46_08090 426ac291f80fab73ce0a4abe700709e0 145 PIRSF PIRSF021697 3 145 8.7E-45 T 14-10-2018 IPR016795 Uncharacterised conserved protein UCP021697, membrane MB46_08090 426ac291f80fab73ce0a4abe700709e0 145 Pfam PF06271 RDD family 71 138 2.7E-6 T 14-10-2018 IPR010432 RDD MB46_11070 d43278210f2d18eaec4083e75ef21e24 479 Pfam PF06762 Lipase maturation factor 126 273 1.5E-56 T 14-10-2018 IPR009613 Lipase maturation factor Reactome: R-HSA-8963889 MB46_11070 d43278210f2d18eaec4083e75ef21e24 479 Pfam PF06762 Lipase maturation factor 297 471 2.8E-53 T 14-10-2018 IPR009613 Lipase maturation factor Reactome: R-HSA-8963889 MB46_03275 435b4bbf2fe19fc98b0223be1db28a3a 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 3.0E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MB46_03275 435b4bbf2fe19fc98b0223be1db28a3a 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 11 24 3.0E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MB46_03275 435b4bbf2fe19fc98b0223be1db28a3a 190 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 57 2.8E-17 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MB46_03275 435b4bbf2fe19fc98b0223be1db28a3a 190 Gene3D G3DSA:1.10.357.10 53 189 8.5E-11 T 14-10-2018 MB46_03275 435b4bbf2fe19fc98b0223be1db28a3a 190 SUPERFAMILY SSF46689 6 77 7.98E-17 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MB46_03275 435b4bbf2fe19fc98b0223be1db28a3a 190 Gene3D G3DSA:1.10.10.60 6 52 1.9E-17 T 14-10-2018 MB46_13490 d54e6087ad21fc191c048f21f2f1e023 161 SUPERFAMILY SSF55826 20 157 1.7E-29 T 14-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 MB46_13490 d54e6087ad21fc191c048f21f2f1e023 161 Gene3D G3DSA:3.90.960.10 14 159 2.8E-34 T 14-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 MB46_13490 d54e6087ad21fc191c048f21f2f1e023 161 Pfam PF04073 Aminoacyl-tRNA editing domain 31 147 1.8E-24 T 14-10-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 MB46_18150 9a438f1c7f77bc4ab10939f1765a556c 410 Gene3D G3DSA:1.20.1250.20 30 214 3.4E-6 T 14-10-2018 MB46_18150 9a438f1c7f77bc4ab10939f1765a556c 410 Gene3D G3DSA:1.20.1250.20 229 406 5.0E-10 T 14-10-2018 MB46_18150 9a438f1c7f77bc4ab10939f1765a556c 410 SUPERFAMILY SSF103473 33 403 1.31E-19 T 14-10-2018 IPR036259 MFS transporter superfamily MB46_01740 f5106452c80445084e2f4e573296be62 365 Gene3D G3DSA:3.40.50.720 27 192 6.0E-46 T 14-10-2018 MB46_01740 f5106452c80445084e2f4e573296be62 365 Gene3D G3DSA:3.30.360.10 193 360 3.2E-44 T 14-10-2018 MB46_01740 f5106452c80445084e2f4e573296be62 365 SUPERFAMILY SSF51735 12 188 7.68E-47 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_01740 f5106452c80445084e2f4e573296be62 365 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 28 153 1.0E-20 T 14-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 MB46_01740 f5106452c80445084e2f4e573296be62 365 SUPERFAMILY SSF55347 163 325 2.45E-33 T 14-10-2018 MB46_19365 ffb189d36060f6e96224de78e14ae488 825 SUPERFAMILY SSF48230 71 427 3.01E-78 T 14-10-2018 IPR008929 Chondroitin AC/alginate lyase Reactome: R-HSA-2022923 MB46_19365 ffb189d36060f6e96224de78e14ae488 825 Pfam PF02884 Polysaccharide lyase family 8, C-terminal beta-sandwich domain 713 776 2.1E-11 T 14-10-2018 IPR004103 Polysaccharide lyase family 8, C-terminal GO:0005576|GO:0016829 MB46_19365 ffb189d36060f6e96224de78e14ae488 825 SUPERFAMILY SSF74650 432 718 5.76E-69 T 14-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 MB46_19365 ffb189d36060f6e96224de78e14ae488 825 Gene3D G3DSA:2.70.98.10 430 708 3.8E-80 T 14-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 MB46_19365 ffb189d36060f6e96224de78e14ae488 825 Pfam PF08124 Polysaccharide lyase family 8, N terminal alpha-helical domain 60 390 1.0E-95 T 14-10-2018 IPR012970 Polysaccharide lyase 8, N-terminal alpha-helical MB46_19365 ffb189d36060f6e96224de78e14ae488 825 Pfam PF02278 Polysaccharide lyase family 8, super-sandwich domain 434 698 3.7E-73 T 14-10-2018 IPR003159 Polysaccharide lyase family 8, central domain GO:0005576|GO:0016829 MB46_19365 ffb189d36060f6e96224de78e14ae488 825 Gene3D G3DSA:1.50.10.100 45 426 1.1E-108 T 14-10-2018 IPR008929 Chondroitin AC/alginate lyase Reactome: R-HSA-2022923 MB46_19365 ffb189d36060f6e96224de78e14ae488 825 SUPERFAMILY SSF49863 712 824 1.94E-16 T 14-10-2018 IPR011071 Polysaccharide lyase family 8-like, C-terminal GO:0005975 MB46_19365 ffb189d36060f6e96224de78e14ae488 825 Gene3D G3DSA:2.60.220.10 710 825 6.4E-20 T 14-10-2018 IPR011071 Polysaccharide lyase family 8-like, C-terminal GO:0005975 MB46_03690 2b266e0d73ad638d93309f69bef877e2 675 SUPERFAMILY SSF51395 5 369 1.66E-110 T 14-10-2018 MB46_03690 2b266e0d73ad638d93309f69bef877e2 675 SUPERFAMILY SSF51971 336 529 4.59E-40 T 14-10-2018 MB46_03690 2b266e0d73ad638d93309f69bef877e2 675 Gene3D G3DSA:3.50.50.60 474 628 1.6E-113 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_03690 2b266e0d73ad638d93309f69bef877e2 675 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 622 636 4.2E-6 T 14-10-2018 MB46_03690 2b266e0d73ad638d93309f69bef877e2 675 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 379 401 4.2E-6 T 14-10-2018 MB46_03690 2b266e0d73ad638d93309f69bef877e2 675 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 9 333 4.8E-87 T 14-10-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 MB46_03690 2b266e0d73ad638d93309f69bef877e2 675 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 379 643 1.2E-24 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MB46_03690 2b266e0d73ad638d93309f69bef877e2 675 Gene3D G3DSA:3.20.20.70 5 371 2.3E-124 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MB46_03690 2b266e0d73ad638d93309f69bef877e2 675 Gene3D G3DSA:3.40.50.720 378 669 1.6E-113 T 14-10-2018 MB46_03690 2b266e0d73ad638d93309f69bef877e2 675 SUPERFAMILY SSF51905 472 630 1.3E-21 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_03690 2b266e0d73ad638d93309f69bef877e2 675 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 462 480 1.4E-14 T 14-10-2018 MB46_03690 2b266e0d73ad638d93309f69bef877e2 675 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 502 520 1.4E-14 T 14-10-2018 MB46_03690 2b266e0d73ad638d93309f69bef877e2 675 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 621 637 1.4E-14 T 14-10-2018 MB46_03690 2b266e0d73ad638d93309f69bef877e2 675 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 380 399 1.4E-14 T 14-10-2018 MB46_12545 9d521308b3303c3af5fd8006e41914a2 544 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 82 465 3.7E-53 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain MB46_12545 9d521308b3303c3af5fd8006e41914a2 544 PIRSF PIRSF002741 1 535 2.0E-60 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 MB46_12545 9d521308b3303c3af5fd8006e41914a2 544 Gene3D G3DSA:3.10.105.10 295 517 1.8E-103 T 14-10-2018 MB46_12545 9d521308b3303c3af5fd8006e41914a2 544 Gene3D G3DSA:3.90.76.10 71 193 1.8E-103 T 14-10-2018 MB46_12545 9d521308b3303c3af5fd8006e41914a2 544 Gene3D G3DSA:3.40.190.10 52 529 1.8E-103 T 14-10-2018 MB46_12545 9d521308b3303c3af5fd8006e41914a2 544 SUPERFAMILY SSF53850 41 541 2.51E-95 T 14-10-2018 MB46_11715 af7b33b467115ba009216460bb502afe 373 Gene3D G3DSA:2.40.30.10 279 368 4.3E-11 T 14-10-2018 MB46_11715 af7b33b467115ba009216460bb502afe 373 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 1 362 32.868 T 14-10-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 MB46_11715 af7b33b467115ba009216460bb502afe 373 SUPERFAMILY SSF52402 1 238 8.82E-44 T 14-10-2018 MB46_11715 af7b33b467115ba009216460bb502afe 373 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 1 361 2.4E-83 T 14-10-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 MB46_11715 af7b33b467115ba009216460bb502afe 373 Gene3D G3DSA:3.40.50.620 1 205 6.4E-67 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MB46_11715 af7b33b467115ba009216460bb502afe 373 Gene3D G3DSA:2.30.30.280 208 270 1.0E-13 T 14-10-2018 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 MB46_11715 af7b33b467115ba009216460bb502afe 373 Pfam PF03054 tRNA methyl transferase 1 361 5.8E-108 T 14-10-2018 MB46_15495 adf97465f6445ea8f7824e06aa403bdf 183 Gene3D G3DSA:3.40.50.2020 1 182 7.7E-66 T 14-10-2018 MB46_15495 adf97465f6445ea8f7824e06aa403bdf 183 TIGRFAM TIGR01203 HGPRTase: hypoxanthine phosphoribosyltransferase 13 177 6.3E-63 T 14-10-2018 IPR005904 Hypoxanthine phosphoribosyl transferase GO:0004422|GO:0005737|GO:0006166 KEGG: 00230+2.4.2.8|KEGG: 00983+2.4.2.8|MetaCyc: PWY-6599|MetaCyc: PWY-6609|MetaCyc: PWY-6610|MetaCyc: PWY-6620 MB46_15495 adf97465f6445ea8f7824e06aa403bdf 183 SUPERFAMILY SSF53271 5 183 2.74E-56 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like MB46_15495 adf97465f6445ea8f7824e06aa403bdf 183 Pfam PF00156 Phosphoribosyl transferase domain 17 164 9.8E-25 T 14-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 MB46_09995 a266c4b05a44563b78e4dc74582e0eeb 719 Gene3D G3DSA:2.150.10.10 579 686 2.5E-6 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal MB46_09995 a266c4b05a44563b78e4dc74582e0eeb 719 SUPERFAMILY SSF101967 581 680 3.14E-7 T 14-10-2018 MB46_09995 a266c4b05a44563b78e4dc74582e0eeb 719 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 402 426 1.8E-4 T 14-10-2018 IPR023908 xxxLxxG heptad repeat MB46_09995 a266c4b05a44563b78e4dc74582e0eeb 719 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 452 474 2.1E-4 T 14-10-2018 IPR023908 xxxLxxG heptad repeat MB46_09995 a266c4b05a44563b78e4dc74582e0eeb 719 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 439 463 1.9E-4 T 14-10-2018 IPR023908 xxxLxxG heptad repeat MB46_15825 77d70ccb5c0209fd921b26f025164258 269 PIRSF PIRSF030802 2 246 4.7E-17 T 14-10-2018 IPR024197 Uncharacterised conserved protein UCP030802 MB46_15825 77d70ccb5c0209fd921b26f025164258 269 Gene3D G3DSA:3.40.50.1000 3 156 2.4E-12 T 14-10-2018 IPR023214 HAD superfamily MB46_15825 77d70ccb5c0209fd921b26f025164258 269 SUPERFAMILY SSF56784 5 228 7.95E-17 T 14-10-2018 IPR036412 HAD-like superfamily MB46_16690 587e125e3d6451054e8a70719e4ba14f 315 Gene3D G3DSA:3.40.190.120 147 253 1.1E-73 T 14-10-2018 MB46_16690 587e125e3d6451054e8a70719e4ba14f 315 SUPERFAMILY SSF53850 48 313 1.3E-47 T 14-10-2018 MB46_16690 587e125e3d6451054e8a70719e4ba14f 315 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 48 309 6.8E-53 T 14-10-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0022857|GO:0043190|GO:0055085 MB46_16690 587e125e3d6451054e8a70719e4ba14f 315 Gene3D G3DSA:3.40.190.10 50 313 1.1E-73 T 14-10-2018 MB46_14395 7e635a4ee4abaa6b2bb6ca968dcc9011 524 Gene3D G3DSA:3.50.50.60 30 396 2.2E-106 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_14395 7e635a4ee4abaa6b2bb6ca968dcc9011 524 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 42 52 5.2E-28 T 14-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 MB46_14395 7e635a4ee4abaa6b2bb6ca968dcc9011 524 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 346 352 5.2E-28 T 14-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 MB46_14395 7e635a4ee4abaa6b2bb6ca968dcc9011 524 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 377 389 5.2E-28 T 14-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 MB46_14395 7e635a4ee4abaa6b2bb6ca968dcc9011 524 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 29 41 5.2E-28 T 14-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 MB46_14395 7e635a4ee4abaa6b2bb6ca968dcc9011 524 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 58 70 5.2E-28 T 14-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 MB46_14395 7e635a4ee4abaa6b2bb6ca968dcc9011 524 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 104 116 5.2E-28 T 14-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 MB46_14395 7e635a4ee4abaa6b2bb6ca968dcc9011 524 Pfam PF01266 FAD dependent oxidoreductase 30 360 3.7E-51 T 14-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 MB46_14395 7e635a4ee4abaa6b2bb6ca968dcc9011 524 ProSitePatterns PS00978 FAD-dependent glycerol-3-phosphate dehydrogenase signature 2. 382 392 - T 14-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 MB46_14395 7e635a4ee4abaa6b2bb6ca968dcc9011 524 Gene3D G3DSA:3.30.9.10 108 353 2.2E-106 T 14-10-2018 MB46_14395 7e635a4ee4abaa6b2bb6ca968dcc9011 524 ProSitePatterns PS00977 FAD-dependent glycerol-3-phosphate dehydrogenase signature 1. 34 51 - T 14-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 MB46_14395 7e635a4ee4abaa6b2bb6ca968dcc9011 524 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 409 517 5.9E-17 T 14-10-2018 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 MB46_14395 7e635a4ee4abaa6b2bb6ca968dcc9011 524 SUPERFAMILY SSF51905 29 355 3.11E-33 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_14395 7e635a4ee4abaa6b2bb6ca968dcc9011 524 Gene3D G3DSA:1.10.8.870 429 524 3.8E-15 T 14-10-2018 IPR038299 Alpha-glycerophosphate oxidase, C-terminal domain superfamily KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 MB46_15230 a0e4a10db680f32db88abe1697122e3a 300 Gene3D G3DSA:3.20.20.190 1 288 4.3E-52 T 14-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 MB46_15230 a0e4a10db680f32db88abe1697122e3a 300 SUPERFAMILY SSF51695 3 282 1.02E-55 T 14-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 MB46_15230 a0e4a10db680f32db88abe1697122e3a 300 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 8 277 8.8E-32 T 14-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 MB46_02765 4ace162c268e60f042d75e6115a1c2bb 475 PIRSF PIRSF000350 2 473 2.3E-75 T 14-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 MB46_02765 4ace162c268e60f042d75e6115a1c2bb 475 Gene3D G3DSA:3.30.390.30 352 473 8.5E-34 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 MB46_02765 4ace162c268e60f042d75e6115a1c2bb 475 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 15 339 6.6E-55 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MB46_02765 4ace162c268e60f042d75e6115a1c2bb 475 Gene3D G3DSA:3.50.50.60 166 284 4.5E-93 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_02765 4ace162c268e60f042d75e6115a1c2bb 475 Gene3D G3DSA:3.50.50.60 17 342 4.5E-93 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_02765 4ace162c268e60f042d75e6115a1c2bb 475 SUPERFAMILY SSF51905 16 348 4.56E-46 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_02765 4ace162c268e60f042d75e6115a1c2bb 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 152 170 2.8E-31 T 14-10-2018 MB46_02765 4ace162c268e60f042d75e6115a1c2bb 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 304 326 2.8E-31 T 14-10-2018 MB46_02765 4ace162c268e60f042d75e6115a1c2bb 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 191 209 2.8E-31 T 14-10-2018 MB46_02765 4ace162c268e60f042d75e6115a1c2bb 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 16 35 2.8E-31 T 14-10-2018 MB46_02765 4ace162c268e60f042d75e6115a1c2bb 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 275 291 2.8E-31 T 14-10-2018 MB46_02765 4ace162c268e60f042d75e6115a1c2bb 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 155 164 1.5E-47 T 14-10-2018 MB46_02765 4ace162c268e60f042d75e6115a1c2bb 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 47 62 1.5E-47 T 14-10-2018 MB46_02765 4ace162c268e60f042d75e6115a1c2bb 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 191 216 1.5E-47 T 14-10-2018 MB46_02765 4ace162c268e60f042d75e6115a1c2bb 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 276 290 1.5E-47 T 14-10-2018 MB46_02765 4ace162c268e60f042d75e6115a1c2bb 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 442 462 1.5E-47 T 14-10-2018 MB46_02765 4ace162c268e60f042d75e6115a1c2bb 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 319 326 1.5E-47 T 14-10-2018 MB46_02765 4ace162c268e60f042d75e6115a1c2bb 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 420 435 1.5E-47 T 14-10-2018 MB46_02765 4ace162c268e60f042d75e6115a1c2bb 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 355 376 1.5E-47 T 14-10-2018 MB46_02765 4ace162c268e60f042d75e6115a1c2bb 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 15 37 1.5E-47 T 14-10-2018 MB46_02765 4ace162c268e60f042d75e6115a1c2bb 475 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 360 467 6.1E-24 T 14-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 MB46_02765 4ace162c268e60f042d75e6115a1c2bb 475 SUPERFAMILY SSF55424 359 473 1.89E-27 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 MB46_13565 c349d6e93ff172753d172a96ed667a85 341 ProSitePatterns PS00433 Phosphofructokinase signature. 265 283 - T 14-10-2018 IPR015912 Phosphofructokinase, conserved site GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 MB46_13565 c349d6e93ff172753d172a96ed667a85 341 Pfam PF00365 Phosphofructokinase 2 295 8.0E-103 T 14-10-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 MB46_13565 c349d6e93ff172753d172a96ed667a85 341 SUPERFAMILY SSF53784 1 331 2.75E-118 T 14-10-2018 IPR035966 Phosphofructokinase superfamily GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 MB46_13565 c349d6e93ff172753d172a96ed667a85 341 Gene3D G3DSA:3.40.50.460 140 277 5.6E-108 T 14-10-2018 MB46_13565 c349d6e93ff172753d172a96ed667a85 341 TIGRFAM TIGR02483 PFK_mixed: phosphofructokinase 2 321 5.3E-143 T 14-10-2018 IPR012829 Phosphofructokinase, mixed-substrate PFK group III GO:0006096|GO:0047334 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 MB46_13565 c349d6e93ff172753d172a96ed667a85 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 261 283 6.3E-72 T 14-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 MB46_13565 c349d6e93ff172753d172a96ed667a85 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 5 24 6.3E-72 T 14-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 MB46_13565 c349d6e93ff172753d172a96ed667a85 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 93 109 6.3E-72 T 14-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 MB46_13565 c349d6e93ff172753d172a96ed667a85 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 211 223 6.3E-72 T 14-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 MB46_13565 c349d6e93ff172753d172a96ed667a85 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 158 174 6.3E-72 T 14-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 MB46_13565 c349d6e93ff172753d172a96ed667a85 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 176 193 6.3E-72 T 14-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 MB46_13565 c349d6e93ff172753d172a96ed667a85 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 31 44 6.3E-72 T 14-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 MB46_13565 c349d6e93ff172753d172a96ed667a85 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 120 137 6.3E-72 T 14-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 MB46_13565 c349d6e93ff172753d172a96ed667a85 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 138 156 6.3E-72 T 14-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 MB46_13565 c349d6e93ff172753d172a96ed667a85 341 PIRSF PIRSF000532 1 340 4.6E-119 T 14-10-2018 IPR012003 ATP-dependent 6-phosphofructokinase, prokaryotic-type GO:0005524|GO:0006002|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 MB46_13565 c349d6e93ff172753d172a96ed667a85 341 Hamap MF_01976 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase [pfp]. 1 341 40.798 T 14-10-2018 IPR012829 Phosphofructokinase, mixed-substrate PFK group III GO:0006096|GO:0047334 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 MB46_13565 c349d6e93ff172753d172a96ed667a85 341 Gene3D G3DSA:3.40.50.450 3 321 5.6E-108 T 14-10-2018 MB46_07585 27c700faa8501948afc19700aee6430e 321 Pfam PF13276 HTH-like domain 66 106 1.2E-7 T 14-10-2018 IPR025948 HTH-like domain MB46_07585 27c700faa8501948afc19700aee6430e 321 Pfam PF00665 Integrase core domain 130 249 7.7E-25 T 14-10-2018 IPR001584 Integrase, catalytic core GO:0015074 MB46_07585 27c700faa8501948afc19700aee6430e 321 SUPERFAMILY SSF53098 124 295 8.5E-34 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily MB46_07585 27c700faa8501948afc19700aee6430e 321 Gene3D G3DSA:3.30.420.10 128 282 1.4E-12 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 MB46_02600 b4aa1c29127587804154f5d1755f2214 381 SUPERFAMILY SSF53448 20 302 5.63E-52 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MB46_02600 b4aa1c29127587804154f5d1755f2214 381 SUPERFAMILY SSF159283 319 373 6.28E-12 T 14-10-2018 MB46_02600 b4aa1c29127587804154f5d1755f2214 381 Pfam PF00483 Nucleotidyl transferase 22 306 4.1E-42 T 14-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 MB46_02600 b4aa1c29127587804154f5d1755f2214 381 Gene3D G3DSA:3.90.550.10 20 375 1.7E-103 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MB46_06350 47abd53962d04567d96d994c40bc6a35 554 PIRSF PIRSF002741 8 554 2.2E-97 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 MB46_06350 47abd53962d04567d96d994c40bc6a35 554 Gene3D G3DSA:3.40.190.10 27 299 7.5E-62 T 14-10-2018 MB46_06350 47abd53962d04567d96d994c40bc6a35 554 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 90 446 1.8E-75 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain MB46_06350 47abd53962d04567d96d994c40bc6a35 554 SUPERFAMILY SSF53850 43 552 2.71E-118 T 14-10-2018 MB46_06350 47abd53962d04567d96d994c40bc6a35 554 Gene3D G3DSA:3.10.105.10 300 523 8.0E-52 T 14-10-2018 MB46_06000 6e081a9db33a8c272eb260bb8b4040e5 334 Pfam PF13377 Periplasmic binding protein-like domain 170 331 8.1E-33 T 14-10-2018 MB46_06000 6e081a9db33a8c272eb260bb8b4040e5 334 SUPERFAMILY SSF47413 2 59 3.66E-16 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MB46_06000 6e081a9db33a8c272eb260bb8b4040e5 334 Gene3D G3DSA:1.10.260.40 1 60 3.9E-21 T 14-10-2018 MB46_06000 6e081a9db33a8c272eb260bb8b4040e5 334 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 49 5.5E-16 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MB46_06000 6e081a9db33a8c272eb260bb8b4040e5 334 Gene3D G3DSA:3.40.50.2300 158 292 1.2E-62 T 14-10-2018 MB46_06000 6e081a9db33a8c272eb260bb8b4040e5 334 SUPERFAMILY SSF53822 63 332 3.08E-57 T 14-10-2018 IPR028082 Periplasmic binding protein-like I MB46_06000 6e081a9db33a8c272eb260bb8b4040e5 334 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 14-10-2018 MB46_06000 6e081a9db33a8c272eb260bb8b4040e5 334 Gene3D G3DSA:3.40.50.2300 61 314 1.2E-62 T 14-10-2018 MB46_06000 6e081a9db33a8c272eb260bb8b4040e5 334 SMART SM00354 2 72 8.1E-23 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MB46_14465 7d05e7b5e66cbb30c89f7a6f1b40d147 296 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 22 197 1.4E-49 T 14-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 MB46_14465 7d05e7b5e66cbb30c89f7a6f1b40d147 296 Gene3D G3DSA:3.40.50.720 8 202 2.5E-51 T 14-10-2018 MB46_14465 7d05e7b5e66cbb30c89f7a6f1b40d147 296 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 200 295 6.3E-27 T 14-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 MB46_14465 7d05e7b5e66cbb30c89f7a6f1b40d147 296 Gene3D G3DSA:1.10.1040.10 203 296 1.3E-31 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MB46_14465 7d05e7b5e66cbb30c89f7a6f1b40d147 296 SUPERFAMILY SSF51735 22 199 3.2E-44 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_14465 7d05e7b5e66cbb30c89f7a6f1b40d147 296 SUPERFAMILY SSF48179 199 295 2.04E-28 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MB46_14465 7d05e7b5e66cbb30c89f7a6f1b40d147 296 PIRSF PIRSF000105 15 296 2.4E-68 T 14-10-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 MB46_02025 d4dd83221ee76062f3a1533a5ee30d01 477 SUPERFAMILY SSF51905 161 360 1.86E-16 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_02025 d4dd83221ee76062f3a1533a5ee30d01 477 SUPERFAMILY SSF51905 11 221 4.12E-25 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_02025 d4dd83221ee76062f3a1533a5ee30d01 477 Gene3D G3DSA:3.50.50.100 4 420 1.9E-102 T 14-10-2018 MB46_02025 d4dd83221ee76062f3a1533a5ee30d01 477 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 12 349 3.3E-41 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MB46_02025 d4dd83221ee76062f3a1533a5ee30d01 477 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 13 32 4.0E-8 T 14-10-2018 MB46_02025 d4dd83221ee76062f3a1533a5ee30d01 477 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 171 189 4.0E-8 T 14-10-2018 MB46_02025 d4dd83221ee76062f3a1533a5ee30d01 477 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 111 129 4.0E-8 T 14-10-2018 MB46_08965 bf8dbc1ae7d9aa69be05fbb1eaec0db4 102 Pfam PF00829 Ribosomal prokaryotic L21 protein 3 101 1.0E-27 T 14-10-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_08965 bf8dbc1ae7d9aa69be05fbb1eaec0db4 102 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 2 102 18.175 T 14-10-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_08965 bf8dbc1ae7d9aa69be05fbb1eaec0db4 102 TIGRFAM TIGR00061 L21: ribosomal protein bL21 3 101 9.4E-21 T 14-10-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_08965 bf8dbc1ae7d9aa69be05fbb1eaec0db4 102 ProSitePatterns PS01169 Ribosomal protein L21 signature. 72 94 - T 14-10-2018 IPR018258 Ribosomal protein L21, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 MB46_08965 bf8dbc1ae7d9aa69be05fbb1eaec0db4 102 SUPERFAMILY SSF141091 2 101 5.62E-28 T 14-10-2018 IPR036164 L21-like superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_09530 a0cd5184c2410c46fe51828279156e23 732 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 73 521 6.8E-163 T 14-10-2018 IPR000060 BCCT transporter family GO:0016020|GO:0022857|GO:0071705 MB46_09530 a0cd5184c2410c46fe51828279156e23 732 ProSitePatterns PS01303 BCCT family of transporters signature. 336 345 - T 14-10-2018 IPR018093 BCCT transporter, conserved site MB46_09530 a0cd5184c2410c46fe51828279156e23 732 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 35 519 1.8E-174 T 14-10-2018 IPR000060 BCCT transporter family GO:0016020|GO:0022857|GO:0071705 MB46_06115 2ac9d3706c5ed8246afa3e6926e584dc 262 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 24 252 1.7E-60 T 14-10-2018 MB46_06115 2ac9d3706c5ed8246afa3e6926e584dc 262 Gene3D G3DSA:3.40.50.720 2 257 5.5E-74 T 14-10-2018 MB46_06115 2ac9d3706c5ed8246afa3e6926e584dc 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 2.1E-32 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_06115 2ac9d3706c5ed8246afa3e6926e584dc 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 2.1E-32 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_06115 2ac9d3706c5ed8246afa3e6926e584dc 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 19 36 2.1E-32 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_06115 2ac9d3706c5ed8246afa3e6926e584dc 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 2.1E-32 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_06115 2ac9d3706c5ed8246afa3e6926e584dc 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 2.1E-32 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_06115 2ac9d3706c5ed8246afa3e6926e584dc 262 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 146 174 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MB46_06115 2ac9d3706c5ed8246afa3e6926e584dc 262 SUPERFAMILY SSF51735 13 253 3.36E-75 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_17450 6edabb722ea9a1f6d22a0d47b37c6d28 924 SMART SM00436 127 215 3.2E-40 T 14-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 MB46_17450 6edabb722ea9a1f6d22a0d47b37c6d28 924 Gene3D G3DSA:1.10.460.10 158 596 6.4E-168 T 14-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 MB46_17450 6edabb722ea9a1f6d22a0d47b37c6d28 924 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 16 643 3.4E-231 T 14-10-2018 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 MB46_17450 6edabb722ea9a1f6d22a0d47b37c6d28 924 SMART SM00437 283 556 2.5E-112 T 14-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 MB46_17450 6edabb722ea9a1f6d22a0d47b37c6d28 924 Gene3D G3DSA:2.70.20.10 207 503 6.4E-168 T 14-10-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 MB46_17450 6edabb722ea9a1f6d22a0d47b37c6d28 924 Pfam PF01751 Toprim domain 16 136 3.0E-29 T 14-10-2018 IPR006171 TOPRIM domain MB46_17450 6edabb722ea9a1f6d22a0d47b37c6d28 924 Gene3D G3DSA:1.10.290.10 291 419 6.4E-168 T 14-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 MB46_17450 6edabb722ea9a1f6d22a0d47b37c6d28 924 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 404 420 3.4E-33 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 MB46_17450 6edabb722ea9a1f6d22a0d47b37c6d28 924 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 325 334 3.4E-33 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 MB46_17450 6edabb722ea9a1f6d22a0d47b37c6d28 924 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 519 533 3.4E-33 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 MB46_17450 6edabb722ea9a1f6d22a0d47b37c6d28 924 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 185 203 3.4E-33 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 MB46_17450 6edabb722ea9a1f6d22a0d47b37c6d28 924 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 101 114 3.4E-33 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 MB46_17450 6edabb722ea9a1f6d22a0d47b37c6d28 924 SMART SM00493 14 127 1.1E-33 T 14-10-2018 IPR006171 TOPRIM domain MB46_17450 6edabb722ea9a1f6d22a0d47b37c6d28 924 SUPERFAMILY SSF56712 14 597 4.58E-174 T 14-10-2018 IPR023405 DNA topoisomerase, type IA, core domain MB46_17450 6edabb722ea9a1f6d22a0d47b37c6d28 924 Hamap MF_00952 DNA topoisomerase 1 [topA]. 14 800 51.77 T 14-10-2018 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 MB46_17450 6edabb722ea9a1f6d22a0d47b37c6d28 924 Pfam PF01131 DNA topoisomerase 151 593 1.9E-119 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 MB46_17450 6edabb722ea9a1f6d22a0d47b37c6d28 924 Pfam PF13368 Topoisomerase C-terminal repeat 845 897 1.8E-18 T 14-10-2018 IPR025589 Topoisomerase C-terminal repeat MB46_17450 6edabb722ea9a1f6d22a0d47b37c6d28 924 Pfam PF13368 Topoisomerase C-terminal repeat 694 778 7.7E-12 T 14-10-2018 IPR025589 Topoisomerase C-terminal repeat MB46_17450 6edabb722ea9a1f6d22a0d47b37c6d28 924 Pfam PF13368 Topoisomerase C-terminal repeat 782 833 2.4E-14 T 14-10-2018 IPR025589 Topoisomerase C-terminal repeat MB46_17450 6edabb722ea9a1f6d22a0d47b37c6d28 924 Gene3D G3DSA:3.40.50.140 13 157 2.0E-55 T 14-10-2018 MB46_17450 6edabb722ea9a1f6d22a0d47b37c6d28 924 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 320 334 - T 14-10-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 MB46_11480 f936632ff9cd066747186d525c5fcd9b 212 Gene3D G3DSA:3.90.550.10 1 210 2.6E-28 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MB46_11480 f936632ff9cd066747186d525c5fcd9b 212 Pfam PF00535 Glycosyl transferase family 2 1 110 2.3E-18 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MB46_11480 f936632ff9cd066747186d525c5fcd9b 212 SUPERFAMILY SSF53448 2 196 2.53E-22 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MB46_17020 19c92441d46d2d9b9dbdb90177ff9965 130 SMART SM00450 7 116 2.4E-4 T 14-10-2018 IPR001763 Rhodanese-like domain MB46_17020 19c92441d46d2d9b9dbdb90177ff9965 130 Pfam PF00581 Rhodanese-like domain 12 108 3.8E-6 T 14-10-2018 IPR001763 Rhodanese-like domain MB46_17020 19c92441d46d2d9b9dbdb90177ff9965 130 SUPERFAMILY SSF52821 7 128 8.91E-16 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily MB46_17020 19c92441d46d2d9b9dbdb90177ff9965 130 Gene3D G3DSA:3.40.250.10 1 130 1.6E-34 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily MB46_14800 49151afc0b636aa609363dfd3a4b7964 251 SUPERFAMILY SSF55781 66 249 1.24E-46 T 14-10-2018 MB46_14800 49151afc0b636aa609363dfd3a4b7964 251 Pfam PF09339 IclR helix-turn-helix domain 11 61 3.3E-16 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 MB46_14800 49151afc0b636aa609363dfd3a4b7964 251 Gene3D G3DSA:3.30.450.40 82 251 3.5E-51 T 14-10-2018 IPR029016 GAF-like domain superfamily MB46_14800 49151afc0b636aa609363dfd3a4b7964 251 Pfam PF01614 Bacterial transcriptional regulator 124 246 2.6E-26 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal MB46_14800 49151afc0b636aa609363dfd3a4b7964 251 SUPERFAMILY SSF46785 9 80 2.89E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_14800 49151afc0b636aa609363dfd3a4b7964 251 Gene3D G3DSA:1.10.10.10 8 81 1.6E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_14800 49151afc0b636aa609363dfd3a4b7964 251 SMART SM00346 9 96 4.2E-24 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 MB46_07880 d96500ee6143a8d8b439a7d0687d530c 942 SUPERFAMILY SSF52016 674 937 5.89E-82 T 14-10-2018 MB46_07880 d96500ee6143a8d8b439a7d0687d530c 942 Gene3D G3DSA:1.10.1440.20 635 694 2.5E-22 T 14-10-2018 MB46_07880 d96500ee6143a8d8b439a7d0687d530c 942 Pfam PF00330 Aconitase family (aconitate hydratase) 68 605 2.9E-174 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MB46_07880 d96500ee6143a8d8b439a7d0687d530c 942 Pfam PF00694 Aconitase C-terminal domain 735 864 2.8E-43 T 14-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 MB46_07880 d96500ee6143a8d8b439a7d0687d530c 942 ProSitePatterns PS01244 Aconitase family signature 2. 536 549 - T 14-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 MB46_07880 d96500ee6143a8d8b439a7d0687d530c 942 Gene3D G3DSA:3.30.499.20 9 368 4.0E-154 T 14-10-2018 MB46_07880 d96500ee6143a8d8b439a7d0687d530c 942 PRINTS PR00415 Aconitase family signature 213 228 9.3E-42 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MB46_07880 d96500ee6143a8d8b439a7d0687d530c 942 PRINTS PR00415 Aconitase family signature 474 485 9.3E-42 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MB46_07880 d96500ee6143a8d8b439a7d0687d530c 942 PRINTS PR00415 Aconitase family signature 368 382 9.3E-42 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MB46_07880 d96500ee6143a8d8b439a7d0687d530c 942 PRINTS PR00415 Aconitase family signature 536 549 9.3E-42 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MB46_07880 d96500ee6143a8d8b439a7d0687d530c 942 PRINTS PR00415 Aconitase family signature 275 288 9.3E-42 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MB46_07880 d96500ee6143a8d8b439a7d0687d530c 942 PRINTS PR00415 Aconitase family signature 142 155 9.3E-42 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MB46_07880 d96500ee6143a8d8b439a7d0687d530c 942 PRINTS PR00415 Aconitase family signature 289 302 9.3E-42 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MB46_07880 d96500ee6143a8d8b439a7d0687d530c 942 PRINTS PR00415 Aconitase family signature 199 212 9.3E-42 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MB46_07880 d96500ee6143a8d8b439a7d0687d530c 942 PRINTS PR00415 Aconitase family signature 166 174 9.3E-42 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MB46_07880 d96500ee6143a8d8b439a7d0687d530c 942 SUPERFAMILY SSF53732 6 670 1.15E-216 T 14-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 MB46_07880 d96500ee6143a8d8b439a7d0687d530c 942 Gene3D G3DSA:3.20.19.10 696 940 6.7E-99 T 14-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 MB46_07880 d96500ee6143a8d8b439a7d0687d530c 942 ProSitePatterns PS00450 Aconitase family signature 1. 470 486 - T 14-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 MB46_06765 8864ca8d6907f22bfddcfffd7faac5de 156 Gene3D G3DSA:2.30.110.10 3 141 1.2E-34 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 MB46_06765 8864ca8d6907f22bfddcfffd7faac5de 156 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 15 134 1.9E-22 T 14-10-2018 IPR024747 Pyridoxamine 5'-phosphate oxidase-related MB46_06765 8864ca8d6907f22bfddcfffd7faac5de 156 SUPERFAMILY SSF50475 11 135 1.96E-28 T 14-10-2018 MB46_14215 c4e821defbc25f4c27170f928ba304f0 335 SUPERFAMILY SSF81301 22 202 7.03E-31 T 14-10-2018 MB46_14215 c4e821defbc25f4c27170f928ba304f0 335 SMART SM00954 45 175 1.7E-17 T 14-10-2018 IPR007685 RelA/SpoT GO:0015969 MB46_14215 c4e821defbc25f4c27170f928ba304f0 335 Pfam PF04607 Region found in RelA / SpoT proteins 46 171 2.7E-18 T 14-10-2018 IPR007685 RelA/SpoT GO:0015969 MB46_14215 c4e821defbc25f4c27170f928ba304f0 335 Gene3D G3DSA:3.30.460.10 5 156 1.7E-16 T 14-10-2018 MB46_09810 0f023c6a430a18ca68df44cb25dcfae5 192 Pfam PF03602 Conserved hypothetical protein 95 3 187 2.9E-42 T 14-10-2018 MB46_09810 0f023c6a430a18ca68df44cb25dcfae5 192 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 3 188 3.0E-39 T 14-10-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 MB46_09810 0f023c6a430a18ca68df44cb25dcfae5 192 Gene3D G3DSA:3.40.50.150 1 191 2.4E-49 T 14-10-2018 MB46_09810 0f023c6a430a18ca68df44cb25dcfae5 192 PIRSF PIRSF004553 1 190 7.7E-45 T 14-10-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 MB46_09810 0f023c6a430a18ca68df44cb25dcfae5 192 SUPERFAMILY SSF53335 2 187 8.07E-39 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MB46_09810 0f023c6a430a18ca68df44cb25dcfae5 192 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 124 130 - T 14-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 MB46_19645 a783838cdfb4bf05b359bf903276cbb3 303 SUPERFAMILY SSF103481 177 272 5.62E-6 T 14-10-2018 MB46_19645 a783838cdfb4bf05b359bf903276cbb3 303 SUPERFAMILY SSF103481 23 123 6.28E-8 T 14-10-2018 MB46_19645 a783838cdfb4bf05b359bf903276cbb3 303 Pfam PF00892 EamA-like transporter family 135 271 3.0E-10 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MB46_19645 a783838cdfb4bf05b359bf903276cbb3 303 Pfam PF00892 EamA-like transporter family 2 120 1.9E-17 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MB46_18035 179ce063dfb819452c44b033ce2a6886 382 Pfam PF07690 Major Facilitator Superfamily 4 216 2.0E-18 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MB46_18035 179ce063dfb819452c44b033ce2a6886 382 Gene3D G3DSA:1.20.1250.20 2 171 1.4E-14 T 14-10-2018 MB46_18035 179ce063dfb819452c44b033ce2a6886 382 SUPERFAMILY SSF103473 5 356 2.09E-37 T 14-10-2018 IPR036259 MFS transporter superfamily MB46_18035 179ce063dfb819452c44b033ce2a6886 382 Gene3D G3DSA:1.20.1250.20 180 361 7.9E-13 T 14-10-2018 MB46_18300 1954c483bd9d04920f4fef156a718886 630 SUPERFAMILY SSF54373 225 322 1.41E-30 T 14-10-2018 MB46_18300 1954c483bd9d04920f4fef156a718886 630 Pfam PF01494 FAD binding domain 33 405 3.9E-70 T 14-10-2018 IPR002938 FAD-binding domain GO:0071949 MB46_18300 1954c483bd9d04920f4fef156a718886 630 Gene3D G3DSA:3.50.50.60 34 402 7.5E-121 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_18300 1954c483bd9d04920f4fef156a718886 630 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 354 370 1.1E-32 T 14-10-2018 MB46_18300 1954c483bd9d04920f4fef156a718886 630 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 198 213 1.1E-32 T 14-10-2018 MB46_18300 1954c483bd9d04920f4fef156a718886 630 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 34 56 1.1E-32 T 14-10-2018 MB46_18300 1954c483bd9d04920f4fef156a718886 630 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 339 354 1.1E-32 T 14-10-2018 MB46_18300 1954c483bd9d04920f4fef156a718886 630 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 372 390 1.1E-32 T 14-10-2018 MB46_18300 1954c483bd9d04920f4fef156a718886 630 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 390 406 1.1E-32 T 14-10-2018 MB46_18300 1954c483bd9d04920f4fef156a718886 630 SUPERFAMILY SSF52833 445 628 3.58E-50 T 14-10-2018 IPR036249 Thioredoxin-like superfamily MB46_18300 1954c483bd9d04920f4fef156a718886 630 SUPERFAMILY SSF51905 33 416 3.27E-47 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_18300 1954c483bd9d04920f4fef156a718886 630 Gene3D G3DSA:3.30.9.50 102 319 7.5E-121 T 14-10-2018 MB46_18300 1954c483bd9d04920f4fef156a718886 630 Pfam PF07976 Phenol hydroxylase, C-terminal dimerisation domain 435 594 3.2E-40 T 14-10-2018 IPR012941 Phenol hydroxylase, C-terminal dimerisation domain MB46_18300 1954c483bd9d04920f4fef156a718886 630 Gene3D G3DSA:3.40.30.20 421 627 1.2E-58 T 14-10-2018 IPR038220 Phenol hydroxylase, C-terminal TRX-fold domain superfamily MB46_12215 e0e96e6966df27b0ac9eaa9a417cf34b 256 Hamap MF_01974 Methionine aminopeptidase [map]. 2 255 31.168 T 14-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 MB46_12215 e0e96e6966df27b0ac9eaa9a417cf34b 256 PRINTS PR00599 Methionine aminopeptidase-1 signature 197 209 2.0E-16 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 MB46_12215 e0e96e6966df27b0ac9eaa9a417cf34b 256 PRINTS PR00599 Methionine aminopeptidase-1 signature 166 178 2.0E-16 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 MB46_12215 e0e96e6966df27b0ac9eaa9a417cf34b 256 PRINTS PR00599 Methionine aminopeptidase-1 signature 73 86 2.0E-16 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 MB46_12215 e0e96e6966df27b0ac9eaa9a417cf34b 256 PRINTS PR00599 Methionine aminopeptidase-1 signature 95 111 2.0E-16 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 MB46_12215 e0e96e6966df27b0ac9eaa9a417cf34b 256 SUPERFAMILY SSF55920 1 253 2.36E-61 T 14-10-2018 IPR036005 Creatinase/aminopeptidase-like MB46_12215 e0e96e6966df27b0ac9eaa9a417cf34b 256 Pfam PF00557 Metallopeptidase family M24 14 246 6.0E-38 T 14-10-2018 IPR000994 Peptidase M24 MB46_12215 e0e96e6966df27b0ac9eaa9a417cf34b 256 Gene3D G3DSA:3.90.230.10 1 256 2.0E-70 T 14-10-2018 MB46_12215 e0e96e6966df27b0ac9eaa9a417cf34b 256 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 2 254 3.3E-69 T 14-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 MB46_05660 4336303b2532e91c565d69f33de43be3 341 Gene3D G3DSA:3.40.190.10 124 220 8.8E-35 T 14-10-2018 MB46_05660 4336303b2532e91c565d69f33de43be3 341 Pfam PF09084 NMT1/THI5 like 59 262 5.3E-17 T 14-10-2018 IPR015168 SsuA/THI5-like MB46_05660 4336303b2532e91c565d69f33de43be3 341 SMART SM00062 45 260 0.0041 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MB46_05660 4336303b2532e91c565d69f33de43be3 341 SUPERFAMILY SSF53850 44 264 1.34E-34 T 14-10-2018 MB46_05660 4336303b2532e91c565d69f33de43be3 341 Gene3D G3DSA:3.40.190.10 51 291 8.8E-35 T 14-10-2018 MB46_05660 4336303b2532e91c565d69f33de43be3 341 TIGRFAM TIGR01728 SsuA_fam: ABC transporter, substrate-binding protein, aliphatic sulfonates family 46 334 1.6E-53 T 14-10-2018 IPR010067 Aliphatic sulfonates-binding protein GO:0016020|GO:0042626 MB46_03755 c8c9c6297e0f76e48ab95813eadfecd5 981 SUPERFAMILY SSF52156 759 888 1.2E-33 T 14-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily MB46_03755 c8c9c6297e0f76e48ab95813eadfecd5 981 Gene3D G3DSA:1.10.10.2480 1 63 1.2E-13 T 14-10-2018 MB46_03755 c8c9c6297e0f76e48ab95813eadfecd5 981 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 477 637 3.4E-31 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MB46_03755 c8c9c6297e0f76e48ab95813eadfecd5 981 PRINTS PR00315 GTP-binding elongation factor signature 582 591 1.0E-9 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MB46_03755 c8c9c6297e0f76e48ab95813eadfecd5 981 PRINTS PR00315 GTP-binding elongation factor signature 530 540 1.0E-9 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MB46_03755 c8c9c6297e0f76e48ab95813eadfecd5 981 PRINTS PR00315 GTP-binding elongation factor signature 478 491 1.0E-9 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MB46_03755 c8c9c6297e0f76e48ab95813eadfecd5 981 PRINTS PR00315 GTP-binding elongation factor signature 546 557 1.0E-9 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MB46_03755 c8c9c6297e0f76e48ab95813eadfecd5 981 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 3 980 16.795 T 14-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 MB46_03755 c8c9c6297e0f76e48ab95813eadfecd5 981 Gene3D G3DSA:2.40.30.10 883 981 1.4E-27 T 14-10-2018 MB46_03755 c8c9c6297e0f76e48ab95813eadfecd5 981 Pfam PF11987 Translation-initiation factor 2 766 871 2.0E-32 T 14-10-2018 IPR023115 Translation initiation factor IF- 2, domain 3 MB46_03755 c8c9c6297e0f76e48ab95813eadfecd5 981 Gene3D G3DSA:3.40.50.10050 774 882 1.3E-33 T 14-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily MB46_03755 c8c9c6297e0f76e48ab95813eadfecd5 981 SUPERFAMILY SSF50447 882 980 1.77E-24 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily MB46_03755 c8c9c6297e0f76e48ab95813eadfecd5 981 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 392 439 2.2E-8 T 14-10-2018 IPR006847 Translation initiation factor IF-2, N-terminal MB46_03755 c8c9c6297e0f76e48ab95813eadfecd5 981 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 3 50 4.4E-13 T 14-10-2018 IPR006847 Translation initiation factor IF-2, N-terminal MB46_03755 c8c9c6297e0f76e48ab95813eadfecd5 981 Gene3D G3DSA:2.40.30.10 651 768 9.6E-41 T 14-10-2018 MB46_03755 c8c9c6297e0f76e48ab95813eadfecd5 981 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 385 979 4.5E-226 T 14-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 MB46_03755 c8c9c6297e0f76e48ab95813eadfecd5 981 SUPERFAMILY SSF52540 471 641 2.96E-49 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_03755 c8c9c6297e0f76e48ab95813eadfecd5 981 Pfam PF00009 Elongation factor Tu GTP binding domain 479 639 1.4E-34 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MB46_03755 c8c9c6297e0f76e48ab95813eadfecd5 981 SUPERFAMILY SSF50447 651 734 2.59E-25 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily MB46_03755 c8c9c6297e0f76e48ab95813eadfecd5 981 ProSitePatterns PS01176 Initiation factor 2 signature. 933 955 - T 14-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 MB46_03755 c8c9c6297e0f76e48ab95813eadfecd5 981 Gene3D G3DSA:3.40.50.300 472 650 5.8E-67 T 14-10-2018 MB46_01315 660b454eaded9ec353cbda7172555fdf 244 SUPERFAMILY SSF51351 2 233 2.23E-53 T 14-10-2018 IPR035990 Triosephosphate isomerase superfamily GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MB46_01315 660b454eaded9ec353cbda7172555fdf 244 Pfam PF00121 Triosephosphate isomerase 28 229 6.2E-46 T 14-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MB46_01315 660b454eaded9ec353cbda7172555fdf 244 Gene3D G3DSA:3.20.20.70 1 237 7.9E-63 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MB46_02775 cc546d682fa393b62e545bce271e35e2 729 SUPERFAMILY SSF50692 560 708 8.5E-35 T 14-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily MB46_02775 cc546d682fa393b62e545bce271e35e2 729 Pfam PF00384 Molybdopterin oxidoreductase 73 506 2.8E-71 T 14-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MB46_02775 cc546d682fa393b62e545bce271e35e2 729 SUPERFAMILY SSF53706 7 581 1.83E-148 T 14-10-2018 MB46_02775 cc546d682fa393b62e545bce271e35e2 729 Gene3D G3DSA:2.20.25.90 10 69 1.5E-7 T 14-10-2018 MB46_02775 cc546d682fa393b62e545bce271e35e2 729 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 11 64 4.9E-7 T 14-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MB46_02775 cc546d682fa393b62e545bce271e35e2 729 Gene3D G3DSA:3.40.50.740 78 554 9.8E-141 T 14-10-2018 MB46_02775 cc546d682fa393b62e545bce271e35e2 729 Gene3D G3DSA:3.40.228.10 152 358 9.8E-141 T 14-10-2018 MB46_02775 cc546d682fa393b62e545bce271e35e2 729 Pfam PF01568 Molydopterin dinucleotide binding domain 598 703 8.3E-30 T 14-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 MB46_02775 cc546d682fa393b62e545bce271e35e2 729 SMART SM00926 8 70 5.6E-4 T 14-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MB46_02775 cc546d682fa393b62e545bce271e35e2 729 Gene3D G3DSA:2.40.40.20 597 711 2.2E-31 T 14-10-2018 MB46_17085 90946925353080b06220b458ef8f2d40 152 SUPERFAMILY SSF46955 11 98 5.13E-18 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily MB46_17085 90946925353080b06220b458ef8f2d40 152 Pfam PF13411 MerR HTH family regulatory protein 12 76 1.9E-15 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MB46_17085 90946925353080b06220b458ef8f2d40 152 Gene3D G3DSA:1.10.1660.10 7 111 2.6E-20 T 14-10-2018 MB46_17085 90946925353080b06220b458ef8f2d40 152 SMART SM00422 10 78 4.6E-23 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MB46_13145 0bac85fe64a3e115a450170d44b5a8e6 244 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 3 230 3.2E-44 T 14-10-2018 IPR022496 tRNA threonylcarbamoyl adenosine modification protein TsaB GO:0002949 MB46_13145 0bac85fe64a3e115a450170d44b5a8e6 244 Pfam PF00814 Glycoprotease family 39 154 4.8E-21 T 14-10-2018 IPR000905 Gcp-like domain MB46_13145 0bac85fe64a3e115a450170d44b5a8e6 244 Gene3D G3DSA:3.30.420.40 3 232 1.7E-34 T 14-10-2018 MB46_13145 0bac85fe64a3e115a450170d44b5a8e6 244 Gene3D G3DSA:3.30.420.40 102 196 1.7E-34 T 14-10-2018 MB46_13145 0bac85fe64a3e115a450170d44b5a8e6 244 SUPERFAMILY SSF53067 131 214 2.2E-9 T 14-10-2018 MB46_13145 0bac85fe64a3e115a450170d44b5a8e6 244 SUPERFAMILY SSF53067 3 111 1.88E-17 T 14-10-2018 MB46_09220 d82eb38c737d65118f7b4599df734e8f 331 SUPERFAMILY SSF52317 11 197 2.06E-46 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like MB46_09220 d82eb38c737d65118f7b4599df734e8f 331 Pfam PF01965 DJ-1/PfpI family 13 177 9.7E-21 T 14-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 MB46_09220 d82eb38c737d65118f7b4599df734e8f 331 Gene3D G3DSA:1.10.10.60 220 325 4.6E-26 T 14-10-2018 MB46_09220 d82eb38c737d65118f7b4599df734e8f 331 Gene3D G3DSA:3.40.50.880 10 215 1.9E-55 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like MB46_09220 d82eb38c737d65118f7b4599df734e8f 331 SUPERFAMILY SSF46689 272 321 7.89E-11 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MB46_09220 d82eb38c737d65118f7b4599df734e8f 331 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 272 314 - T 14-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 MB46_09220 d82eb38c737d65118f7b4599df734e8f 331 SMART SM00342 235 318 4.6E-23 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MB46_09220 d82eb38c737d65118f7b4599df734e8f 331 Pfam PF12833 Helix-turn-helix domain 243 319 1.3E-20 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MB46_17870 03480abcaea0d953625f8bc9285c96db 225 SUPERFAMILY SSF52540 17 200 1.23E-19 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_17870 03480abcaea0d953625f8bc9285c96db 225 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 23 151 1.6E-5 T 14-10-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0016301 Reactome: R-HSA-73614 MB46_17870 03480abcaea0d953625f8bc9285c96db 225 Gene3D G3DSA:3.40.50.300 1 203 2.3E-41 T 14-10-2018 MB46_15170 b52571e56745cccbbbf4830b23da69de 363 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 3 346 5.4E-71 T 14-10-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 MB46_15170 b52571e56745cccbbbf4830b23da69de 363 SUPERFAMILY SSF51395 1 350 3.38E-105 T 14-10-2018 MB46_15170 b52571e56745cccbbbf4830b23da69de 363 Gene3D G3DSA:3.20.20.70 1 360 5.6E-116 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MB46_02910 b93f6aeff504a132dc901c1c874c8542 2056 Pfam PF00041 Fibronectin type III domain 1581 1648 5.2E-6 T 14-10-2018 IPR003961 Fibronectin type III GO:0005515 MB46_02910 b93f6aeff504a132dc901c1c874c8542 2056 Pfam PF00041 Fibronectin type III domain 1485 1557 5.1E-7 T 14-10-2018 IPR003961 Fibronectin type III GO:0005515 MB46_02910 b93f6aeff504a132dc901c1c874c8542 2056 SUPERFAMILY SSF49265 1580 1758 3.19E-22 T 14-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 MB46_02910 b93f6aeff504a132dc901c1c874c8542 2056 Gene3D G3DSA:2.60.40.10 1569 1660 9.2E-11 T 14-10-2018 IPR013783 Immunoglobulin-like fold MB46_02910 b93f6aeff504a132dc901c1c874c8542 2056 SMART SM00060 1670 1749 0.01 T 14-10-2018 IPR003961 Fibronectin type III GO:0005515 MB46_02910 b93f6aeff504a132dc901c1c874c8542 2056 SMART SM00060 1572 1652 0.0066 T 14-10-2018 IPR003961 Fibronectin type III GO:0005515 MB46_02910 b93f6aeff504a132dc901c1c874c8542 2056 SMART SM00060 1484 1557 7.2E-11 T 14-10-2018 IPR003961 Fibronectin type III GO:0005515 MB46_02910 b93f6aeff504a132dc901c1c874c8542 2056 SUPERFAMILY SSF49265 1477 1579 1.06E-17 T 14-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 MB46_02910 b93f6aeff504a132dc901c1c874c8542 2056 Gene3D G3DSA:2.60.40.10 1472 1568 2.5E-18 T 14-10-2018 IPR013783 Immunoglobulin-like fold MB46_02910 b93f6aeff504a132dc901c1c874c8542 2056 Gene3D G3DSA:2.60.40.10 1661 1761 7.1E-11 T 14-10-2018 IPR013783 Immunoglobulin-like fold MB46_02860 3d5aedc657642b591e822a94197a6ad3 491 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 382 481 2.9E-24 T 14-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal MB46_02860 3d5aedc657642b591e822a94197a6ad3 491 Gene3D G3DSA:1.10.150.120 93 212 5.0E-28 T 14-10-2018 MB46_02860 3d5aedc657642b591e822a94197a6ad3 491 Gene3D G3DSA:3.30.390.50 383 483 1.3E-24 T 14-10-2018 MB46_02860 3d5aedc657642b591e822a94197a6ad3 491 SUPERFAMILY SSF56176 204 374 1.64E-49 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 MB46_02860 3d5aedc657642b591e822a94197a6ad3 491 SUPERFAMILY SSF55447 381 482 2.22E-27 T 14-10-2018 IPR036683 CO dehydrogenase flavoprotein, C-terminal domain superfamily MB46_02860 3d5aedc657642b591e822a94197a6ad3 491 SUPERFAMILY SSF47741 102 187 1.31E-24 T 14-10-2018 IPR036884 [2Fe-2S]-binding domain superfamily MB46_02860 3d5aedc657642b591e822a94197a6ad3 491 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 48 56 - T 14-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 MB46_02860 3d5aedc657642b591e822a94197a6ad3 491 Gene3D G3DSA:3.30.465.10 213 376 2.7E-49 T 14-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 MB46_02860 3d5aedc657642b591e822a94197a6ad3 491 Pfam PF01799 [2Fe-2S] binding domain 91 178 1.9E-26 T 14-10-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 MB46_02860 3d5aedc657642b591e822a94197a6ad3 491 Gene3D G3DSA:3.10.20.30 11 92 2.2E-22 T 14-10-2018 IPR012675 Beta-grasp domain superfamily MB46_02860 3d5aedc657642b591e822a94197a6ad3 491 SUPERFAMILY SSF54292 12 96 6.28E-14 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 MB46_02860 3d5aedc657642b591e822a94197a6ad3 491 SMART SM01092 382 483 2.2E-25 T 14-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal MB46_02860 3d5aedc657642b591e822a94197a6ad3 491 PIRSF PIRSF036557 10 491 2.1E-166 T 14-10-2018 IPR012175 Xanthine dehydrogenase, small subunit, bacteria MB46_02860 3d5aedc657642b591e822a94197a6ad3 491 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 211 375 3.5E-46 T 14-10-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 MB46_02860 3d5aedc657642b591e822a94197a6ad3 491 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 14 63 4.7E-5 T 14-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MB46_03645 f88dc6960fae3d8febebc14d83b91ccb 344 Gene3D G3DSA:3.40.50.2300 169 299 5.6E-68 T 14-10-2018 MB46_03645 f88dc6960fae3d8febebc14d83b91ccb 344 SUPERFAMILY SSF47413 10 68 1.05E-15 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MB46_03645 f88dc6960fae3d8febebc14d83b91ccb 344 Gene3D G3DSA:3.40.50.2300 64 316 5.6E-68 T 14-10-2018 MB46_03645 f88dc6960fae3d8febebc14d83b91ccb 344 SUPERFAMILY SSF53822 70 342 6.04E-67 T 14-10-2018 IPR028082 Periplasmic binding protein-like I MB46_03645 f88dc6960fae3d8febebc14d83b91ccb 344 Gene3D G3DSA:1.10.260.40 4 63 1.8E-19 T 14-10-2018 MB46_03645 f88dc6960fae3d8febebc14d83b91ccb 344 Pfam PF13377 Periplasmic binding protein-like domain 177 339 1.0E-37 T 14-10-2018 MB46_03645 f88dc6960fae3d8febebc14d83b91ccb 344 Pfam PF00356 Bacterial regulatory proteins, lacI family 13 57 4.6E-13 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MB46_03645 f88dc6960fae3d8febebc14d83b91ccb 344 SMART SM00354 10 80 5.9E-21 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MB46_01415 8566cf1f0152ef28ef9029c5427cfd04 183 Gene3D G3DSA:1.10.1740.10 4 91 1.7E-12 T 14-10-2018 MB46_01415 8566cf1f0152ef28ef9029c5427cfd04 183 SUPERFAMILY SSF88659 112 170 1.64E-12 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like MB46_01415 8566cf1f0152ef28ef9029c5427cfd04 183 Gene3D G3DSA:1.10.10.10 96 172 8.1E-14 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_01415 8566cf1f0152ef28ef9029c5427cfd04 183 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 39 169 5.0E-20 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 MB46_01415 8566cf1f0152ef28ef9029c5427cfd04 183 Pfam PF08281 Sigma-70, region 4 118 168 3.3E-13 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MB46_01415 8566cf1f0152ef28ef9029c5427cfd04 183 Pfam PF04542 Sigma-70 region 2 39 89 4.0E-9 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 MB46_01415 8566cf1f0152ef28ef9029c5427cfd04 183 SUPERFAMILY SSF88946 14 103 5.49E-15 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 MB46_18100 db59b262ed604e016327bcb684f37c79 391 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 210 372 1.7E-32 T 14-10-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 MB46_18100 db59b262ed604e016327bcb684f37c79 391 Gene3D G3DSA:3.40.50.2000 194 366 1.4E-44 T 14-10-2018 MB46_18100 db59b262ed604e016327bcb684f37c79 391 SUPERFAMILY SSF53756 18 385 5.07E-86 T 14-10-2018 MB46_18100 db59b262ed604e016327bcb684f37c79 391 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 19 384 28.772 T 14-10-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0050511 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MB46_18100 db59b262ed604e016327bcb684f37c79 391 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 19 154 2.0E-32 T 14-10-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MB46_18100 db59b262ed604e016327bcb684f37c79 391 Gene3D G3DSA:3.40.50.2000 12 193 1.2E-46 T 14-10-2018 MB46_01295 8821545aa8fa03117fd4423683fd823a 162 Pfam PF02502 Ribose/Galactose Isomerase 11 151 3.5E-44 T 14-10-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 MB46_01295 8821545aa8fa03117fd4423683fd823a 162 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 11 155 4.9E-32 T 14-10-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 MB46_01295 8821545aa8fa03117fd4423683fd823a 162 TIGRFAM TIGR02133 RPI_actino: ribose 5-phosphate isomerase 10 156 6.1E-59 T 14-10-2018 IPR011860 Ribose 5-phosphate isomerase GO:0004751 MB46_01295 8821545aa8fa03117fd4423683fd823a 162 Gene3D G3DSA:3.40.1400.10 1 157 8.5E-46 T 14-10-2018 IPR036569 Sugar-phosphate isomerase, RpiB/LacA/LacB superfamily GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 MB46_01295 8821545aa8fa03117fd4423683fd823a 162 PIRSF PIRSF005384 9 157 1.2E-43 T 14-10-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 MB46_01295 8821545aa8fa03117fd4423683fd823a 162 SUPERFAMILY SSF89623 8 155 5.1E-47 T 14-10-2018 IPR036569 Sugar-phosphate isomerase, RpiB/LacA/LacB superfamily GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 MB46_08330 eae2bdc171691adfcff84de67859e7df 279 Pfam PF01553 Acyltransferase 24 151 9.1E-24 T 14-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 MB46_08330 eae2bdc171691adfcff84de67859e7df 279 SMART SM00563 35 154 2.4E-33 T 14-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 MB46_08330 eae2bdc171691adfcff84de67859e7df 279 SUPERFAMILY SSF69593 3 217 1.57E-49 T 14-10-2018 MB46_00725 a344734378fc4c8fe0579778f0ef5323 404 Gene3D G3DSA:1.10.10.10 7 76 5.6E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_00725 a344734378fc4c8fe0579778f0ef5323 404 Gene3D G3DSA:3.30.420.40 205 376 1.7E-75 T 14-10-2018 MB46_00725 a344734378fc4c8fe0579778f0ef5323 404 ProSitePatterns PS01125 ROK family signature. 215 242 - T 14-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 MB46_00725 a344734378fc4c8fe0579778f0ef5323 404 Pfam PF00480 ROK family 82 391 7.6E-50 T 14-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 MB46_00725 a344734378fc4c8fe0579778f0ef5323 404 Gene3D G3DSA:3.30.420.40 86 386 1.7E-75 T 14-10-2018 MB46_00725 a344734378fc4c8fe0579778f0ef5323 404 SUPERFAMILY SSF53067 79 391 1.3E-50 T 14-10-2018 MB46_00725 a344734378fc4c8fe0579778f0ef5323 404 SUPERFAMILY SSF46785 8 70 8.79E-15 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_04750 8e30474648ae46f0be1544ccbdb7e61c 178 Gene3D G3DSA:1.20.120.80 1 178 1.5E-45 T 14-10-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MB46_04750 8e30474648ae46f0be1544ccbdb7e61c 178 Pfam PF00510 Cytochrome c oxidase subunit III 1 176 3.8E-18 T 14-10-2018 IPR000298 Cytochrome c oxidase subunit III-like GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MB46_04750 8e30474648ae46f0be1544ccbdb7e61c 178 SUPERFAMILY SSF81452 1 177 5.1E-46 T 14-10-2018 IPR035973 Cytochrome c oxidase subunit III-like superfamily GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MB46_01815 41f32f32d2a19441f5ea463e79d26e43 226 Pfam PF00392 Bacterial regulatory proteins, gntR family 24 83 1.1E-15 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MB46_01815 41f32f32d2a19441f5ea463e79d26e43 226 SUPERFAMILY SSF46785 18 99 7.07E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_01815 41f32f32d2a19441f5ea463e79d26e43 226 SUPERFAMILY SSF48008 89 221 4.18E-23 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MB46_01815 41f32f32d2a19441f5ea463e79d26e43 226 Gene3D G3DSA:1.20.120.530 86 223 1.2E-26 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MB46_01815 41f32f32d2a19441f5ea463e79d26e43 226 Pfam PF07729 FCD domain 93 212 9.3E-16 T 14-10-2018 IPR011711 GntR, C-terminal MB46_01815 41f32f32d2a19441f5ea463e79d26e43 226 SMART SM00895 93 213 9.8E-12 T 14-10-2018 IPR011711 GntR, C-terminal MB46_01815 41f32f32d2a19441f5ea463e79d26e43 226 Gene3D G3DSA:1.10.10.10 9 84 2.8E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_01815 41f32f32d2a19441f5ea463e79d26e43 226 SMART SM00345 25 83 5.4E-14 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MB46_08080 c9c0379eb3fa6dd92712ff5915092bbe 338 Pfam PF16881 N-terminal domain of lipoyl synthase of Radical_SAM family 24 60 2.2E-7 T 14-10-2018 IPR031691 Lipoyl synthase, N-terminal KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 MB46_08080 c9c0379eb3fa6dd92712ff5915092bbe 338 Gene3D G3DSA:3.20.20.70 74 279 5.3E-15 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MB46_08080 c9c0379eb3fa6dd92712ff5915092bbe 338 PIRSF PIRSF005963 4 319 2.5E-121 T 14-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 MB46_08080 c9c0379eb3fa6dd92712ff5915092bbe 338 SMART SM00729 71 277 1.3E-11 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 MB46_08080 c9c0379eb3fa6dd92712ff5915092bbe 338 SUPERFAMILY SSF102114 43 309 2.35E-57 T 14-10-2018 MB46_08080 c9c0379eb3fa6dd92712ff5915092bbe 338 TIGRFAM TIGR00510 lipA: lipoyl synthase 22 306 6.4E-102 T 14-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 MB46_08080 c9c0379eb3fa6dd92712ff5915092bbe 338 Pfam PF04055 Radical SAM superfamily 81 235 4.8E-10 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MB46_08080 c9c0379eb3fa6dd92712ff5915092bbe 338 Hamap MF_00206 Lipoyl synthase [lipA]. 1 307 133.73 T 14-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 MB46_12105 7553b29183736c6b639256dab15a85df 218 Gene3D G3DSA:3.30.1360.20 6 100 4.4E-17 T 14-10-2018 IPR036428 Pterin 4 alpha carbinolamine dehydratase superfamily GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 MB46_12105 7553b29183736c6b639256dab15a85df 218 Pfam PF01329 Pterin 4 alpha carbinolamine dehydratase 7 94 3.8E-17 T 14-10-2018 IPR001533 Pterin 4 alpha carbinolamine dehydratase GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 MB46_12105 7553b29183736c6b639256dab15a85df 218 Gene3D G3DSA:3.10.180.10 101 217 1.1E-16 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MB46_12105 7553b29183736c6b639256dab15a85df 218 SUPERFAMILY SSF54593 113 214 2.54E-7 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MB46_12105 7553b29183736c6b639256dab15a85df 218 SUPERFAMILY SSF55248 6 97 5.76E-17 T 14-10-2018 IPR036428 Pterin 4 alpha carbinolamine dehydratase superfamily GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 MB46_02975 81cb67804083c8adbd90c20a08b7d958 280 Pfam PF00459 Inositol monophosphatase family 9 243 1.8E-43 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MB46_02975 81cb67804083c8adbd90c20a08b7d958 280 Gene3D G3DSA:3.30.540.10 2 148 1.6E-35 T 14-10-2018 MB46_02975 81cb67804083c8adbd90c20a08b7d958 280 Gene3D G3DSA:3.40.190.80 163 266 1.3E-20 T 14-10-2018 MB46_02975 81cb67804083c8adbd90c20a08b7d958 280 SUPERFAMILY SSF56655 9 245 7.85E-54 T 14-10-2018 MB46_02975 81cb67804083c8adbd90c20a08b7d958 280 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 88 101 - T 14-10-2018 IPR020583 Inositol monophosphatase, metal-binding site MB46_02975 81cb67804083c8adbd90c20a08b7d958 280 PRINTS PR00377 Inositol monophosphatase superfamily signature 44 64 3.0E-19 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MB46_02975 81cb67804083c8adbd90c20a08b7d958 280 PRINTS PR00377 Inositol monophosphatase superfamily signature 192 213 3.0E-19 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MB46_02975 81cb67804083c8adbd90c20a08b7d958 280 PRINTS PR00377 Inositol monophosphatase superfamily signature 223 247 3.0E-19 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MB46_02975 81cb67804083c8adbd90c20a08b7d958 280 PRINTS PR00377 Inositol monophosphatase superfamily signature 88 104 3.0E-19 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MB46_11900 c2f92540d5c23fcbc41345d3dbe0c2eb 721 Gene3D G3DSA:3.90.226.10 1 319 2.3E-113 T 14-10-2018 MB46_11900 c2f92540d5c23fcbc41345d3dbe0c2eb 721 Gene3D G3DSA:3.40.50.720 320 503 2.2E-67 T 14-10-2018 MB46_11900 c2f92540d5c23fcbc41345d3dbe0c2eb 721 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 322 500 1.4E-60 T 14-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 MB46_11900 c2f92540d5c23fcbc41345d3dbe0c2eb 721 SUPERFAMILY SSF51735 319 501 6.21E-56 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_11900 c2f92540d5c23fcbc41345d3dbe0c2eb 721 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 503 605 1.5E-15 T 14-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 MB46_11900 c2f92540d5c23fcbc41345d3dbe0c2eb 721 Pfam PF00378 Enoyl-CoA hydratase/isomerase 14 205 3.2E-32 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 MB46_11900 c2f92540d5c23fcbc41345d3dbe0c2eb 721 SUPERFAMILY SSF52096 1 302 2.03E-61 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MB46_11900 c2f92540d5c23fcbc41345d3dbe0c2eb 721 Gene3D G3DSA:1.10.1040.50 504 713 1.4E-56 T 14-10-2018 MB46_11900 c2f92540d5c23fcbc41345d3dbe0c2eb 721 SUPERFAMILY SSF48179 631 721 1.87E-15 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MB46_11900 c2f92540d5c23fcbc41345d3dbe0c2eb 721 SUPERFAMILY SSF48179 502 644 4.93E-17 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MB46_05310 ac9da1cc61ce7c799fd2c9f2f1001ea1 236 Gene3D G3DSA:1.10.357.10 27 227 1.8E-27 T 14-10-2018 MB46_05310 ac9da1cc61ce7c799fd2c9f2f1001ea1 236 SUPERFAMILY SSF46689 30 111 5.2E-17 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MB46_05310 ac9da1cc61ce7c799fd2c9f2f1001ea1 236 Pfam PF00440 Bacterial regulatory proteins, tetR family 42 87 4.3E-11 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MB46_05900 530bba4e6cc57936aab2c3829f971915 125 Pfam PF03795 YCII-related domain 1 111 3.0E-14 T 14-10-2018 IPR005545 YCII-related MB46_05900 530bba4e6cc57936aab2c3829f971915 125 SUPERFAMILY SSF54909 1 111 4.56E-22 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel MB46_05900 530bba4e6cc57936aab2c3829f971915 125 Gene3D G3DSA:3.30.70.1060 1 115 4.2E-28 T 14-10-2018 MB46_16210 f60a7295c6e00ca7aee4b93d482278cf 593 Pfam PF03793 PASTA domain 454 509 1.1E-7 T 14-10-2018 IPR005543 PASTA domain MB46_16210 f60a7295c6e00ca7aee4b93d482278cf 593 Pfam PF03793 PASTA domain 521 575 3.2E-10 T 14-10-2018 IPR005543 PASTA domain MB46_16210 f60a7295c6e00ca7aee4b93d482278cf 593 Gene3D G3DSA:1.10.510.10 94 277 2.6E-51 T 14-10-2018 MB46_16210 f60a7295c6e00ca7aee4b93d482278cf 593 Pfam PF00069 Protein kinase domain 15 257 2.5E-47 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 MB46_16210 f60a7295c6e00ca7aee4b93d482278cf 593 Gene3D G3DSA:3.30.10.20 511 577 3.3E-14 T 14-10-2018 MB46_16210 f60a7295c6e00ca7aee4b93d482278cf 593 Gene3D G3DSA:3.30.200.20 1 92 8.6E-29 T 14-10-2018 MB46_16210 f60a7295c6e00ca7aee4b93d482278cf 593 Gene3D G3DSA:3.30.10.20 452 510 9.2E-11 T 14-10-2018 MB46_16210 f60a7295c6e00ca7aee4b93d482278cf 593 SMART SM00220 13 269 2.3E-60 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 MB46_16210 f60a7295c6e00ca7aee4b93d482278cf 593 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 132 144 - T 14-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 MB46_16210 f60a7295c6e00ca7aee4b93d482278cf 593 SMART SM00740 510 576 3.1E-5 T 14-10-2018 IPR005543 PASTA domain MB46_16210 f60a7295c6e00ca7aee4b93d482278cf 593 SMART SM00740 443 509 0.0019 T 14-10-2018 IPR005543 PASTA domain MB46_16210 f60a7295c6e00ca7aee4b93d482278cf 593 SUPERFAMILY SSF56112 10 266 3.1E-75 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily MB46_12255 092388103820226176f432eaaf6949fa 127 Gene3D G3DSA:2.40.50.100 1 125 1.4E-46 T 14-10-2018 MB46_12255 092388103820226176f432eaaf6949fa 127 SUPERFAMILY SSF51230 6 122 5.5E-38 T 14-10-2018 IPR011053 Single hybrid motif MB46_12255 092388103820226176f432eaaf6949fa 127 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 5 124 35.417 T 14-10-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 MB46_12255 092388103820226176f432eaaf6949fa 127 Pfam PF01597 Glycine cleavage H-protein 8 120 7.3E-40 T 14-10-2018 IPR033753 Glycine cleavage system H-protein/Simiate MB46_12255 092388103820226176f432eaaf6949fa 127 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 49 78 - T 14-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 MB46_12255 092388103820226176f432eaaf6949fa 127 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 6 121 2.1E-43 T 14-10-2018 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 MB46_15275 5e5fe546a2cc3bea127092fe8309bb5d 91 PRINTS PR00107 Phosphocarrier protein signature 57 74 2.3E-7 T 14-10-2018 IPR000032 Phosphocarrier protein HPr-like MB46_15275 5e5fe546a2cc3bea127092fe8309bb5d 91 PRINTS PR00107 Phosphocarrier protein signature 13 29 2.3E-7 T 14-10-2018 IPR000032 Phosphocarrier protein HPr-like MB46_15275 5e5fe546a2cc3bea127092fe8309bb5d 91 PRINTS PR00107 Phosphocarrier protein signature 42 57 2.3E-7 T 14-10-2018 IPR000032 Phosphocarrier protein HPr-like MB46_15275 5e5fe546a2cc3bea127092fe8309bb5d 91 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 1 85 1.4E-21 T 14-10-2018 IPR000032 Phosphocarrier protein HPr-like MB46_15275 5e5fe546a2cc3bea127092fe8309bb5d 91 Pfam PF00381 PTS HPr component phosphorylation site 3 86 3.3E-21 T 14-10-2018 IPR000032 Phosphocarrier protein HPr-like MB46_15275 5e5fe546a2cc3bea127092fe8309bb5d 91 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 13 20 - T 14-10-2018 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site MB46_15275 5e5fe546a2cc3bea127092fe8309bb5d 91 Gene3D G3DSA:3.30.1340.10 1 89 3.7E-20 T 14-10-2018 IPR035895 HPr-like superfamily MB46_15275 5e5fe546a2cc3bea127092fe8309bb5d 91 ProSitePatterns PS00589 PTS HPR domain serine phosphorylation site signature. 43 58 - T 14-10-2018 IPR002114 Phosphotransferase system, HPr serine phosphorylation site MB46_15275 5e5fe546a2cc3bea127092fe8309bb5d 91 SUPERFAMILY SSF55594 1 90 2.49E-18 T 14-10-2018 IPR035895 HPr-like superfamily MB46_18110 c7cc20857041447135cc80f5d76174f9 227 Pfam PF13761 Domain of unknown function (DUF4166) 16 202 1.0E-51 T 14-10-2018 IPR025311 Domain of unknown function DUF4166 MB46_00495 93c12e9059424388ae1858100fe03894 155 Gene3D G3DSA:1.10.10.10 1 59 7.5E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_00495 93c12e9059424388ae1858100fe03894 155 Gene3D G3DSA:3.30.70.920 62 148 4.4E-16 T 14-10-2018 MB46_00495 93c12e9059424388ae1858100fe03894 155 SUPERFAMILY SSF54909 66 146 1.47E-16 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel MB46_00495 93c12e9059424388ae1858100fe03894 155 Pfam PF13404 AsnC-type helix-turn-helix domain 6 47 5.6E-13 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 MB46_00495 93c12e9059424388ae1858100fe03894 155 SUPERFAMILY SSF46785 6 61 5.61E-14 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_00495 93c12e9059424388ae1858100fe03894 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 22 33 2.7E-10 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 MB46_00495 93c12e9059424388ae1858100fe03894 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 33 52 2.7E-10 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 MB46_00495 93c12e9059424388ae1858100fe03894 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 6 22 2.7E-10 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 MB46_00495 93c12e9059424388ae1858100fe03894 155 SMART SM00344 6 112 1.4E-24 T 14-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 MB46_00495 93c12e9059424388ae1858100fe03894 155 Pfam PF01037 Lrp/AsnC ligand binding domain 82 141 2.3E-14 T 14-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain MB46_01510 997b72e586d178c952aed43baf729af6 427 Gene3D G3DSA:3.40.190.10 35 427 4.1E-71 T 14-10-2018 MB46_01510 997b72e586d178c952aed43baf729af6 427 SUPERFAMILY SSF53850 25 425 7.7E-72 T 14-10-2018 MB46_01510 997b72e586d178c952aed43baf729af6 427 Pfam PF13416 Bacterial extracellular solute-binding protein 59 370 5.5E-34 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein MB46_17725 eaf8c1d8408efce93ce5480f8e70282d 336 Pfam PF05448 Acetyl xylan esterase (AXE1) 1 331 4.6E-95 T 14-10-2018 IPR008391 Acetyl xylan esterase MB46_17725 eaf8c1d8408efce93ce5480f8e70282d 336 SUPERFAMILY SSF53474 4 318 2.89E-31 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_17725 eaf8c1d8408efce93ce5480f8e70282d 336 Gene3D G3DSA:3.40.50.1820 1 335 5.5E-78 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_05520 38881459f3430c0474c0ebfa32e8f9e3 796 Gene3D G3DSA:1.20.1580.10 583 621 1.5E-104 T 14-10-2018 MB46_05520 38881459f3430c0474c0ebfa32e8f9e3 796 Gene3D G3DSA:1.10.8.280 190 298 3.3E-152 T 14-10-2018 MB46_05520 38881459f3430c0474c0ebfa32e8f9e3 796 Gene3D G3DSA:3.40.50.300 24 477 3.3E-152 T 14-10-2018 MB46_05520 38881459f3430c0474c0ebfa32e8f9e3 796 SUPERFAMILY SSF52540 500 768 3.23E-38 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_05520 38881459f3430c0474c0ebfa32e8f9e3 796 Pfam PF00005 ABC transporter 507 714 2.1E-12 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_05520 38881459f3430c0474c0ebfa32e8f9e3 796 Gene3D G3DSA:3.40.50.300 501 790 1.5E-104 T 14-10-2018 MB46_05520 38881459f3430c0474c0ebfa32e8f9e3 796 SUPERFAMILY SSF52540 23 457 4.81E-30 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_05520 38881459f3430c0474c0ebfa32e8f9e3 796 Gene3D G3DSA:1.20.1580.10 110 376 3.3E-152 T 14-10-2018 MB46_17720 34392f429a7843e6c8572b8d57292c5c 352 Gene3D G3DSA:3.40.50.2300 87 322 4.8E-52 T 14-10-2018 MB46_17720 34392f429a7843e6c8572b8d57292c5c 352 Gene3D G3DSA:1.10.260.40 10 69 5.2E-20 T 14-10-2018 MB46_17720 34392f429a7843e6c8572b8d57292c5c 352 SMART SM00354 11 81 3.4E-22 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MB46_17720 34392f429a7843e6c8572b8d57292c5c 352 SUPERFAMILY SSF53822 72 339 8.64E-48 T 14-10-2018 IPR028082 Periplasmic binding protein-like I MB46_17720 34392f429a7843e6c8572b8d57292c5c 352 SUPERFAMILY SSF47413 11 68 6.38E-15 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MB46_17720 34392f429a7843e6c8572b8d57292c5c 352 Pfam PF13377 Periplasmic binding protein-like domain 179 337 2.0E-29 T 14-10-2018 MB46_17720 34392f429a7843e6c8572b8d57292c5c 352 ProSitePatterns PS00356 LacI-type HTH domain signature. 14 32 - T 14-10-2018 MB46_17720 34392f429a7843e6c8572b8d57292c5c 352 Gene3D G3DSA:3.40.50.2300 169 296 4.8E-52 T 14-10-2018 MB46_17720 34392f429a7843e6c8572b8d57292c5c 352 Pfam PF00356 Bacterial regulatory proteins, lacI family 13 58 8.6E-16 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MB46_15420 3af8da9182bcc37968450382e3525470 482 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 3 481 1.9E-138 T 14-10-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MB46_15420 3af8da9182bcc37968450382e3525470 482 Pfam PF01336 OB-fold nucleic acid binding domain 51 126 1.8E-8 T 14-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 MB46_15420 3af8da9182bcc37968450382e3525470 482 PRINTS PR00982 Lysyl-tRNA synthetase signature 365 381 2.5E-31 T 14-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MB46_15420 3af8da9182bcc37968450382e3525470 482 PRINTS PR00982 Lysyl-tRNA synthetase signature 180 190 2.5E-31 T 14-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MB46_15420 3af8da9182bcc37968450382e3525470 482 PRINTS PR00982 Lysyl-tRNA synthetase signature 196 212 2.5E-31 T 14-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MB46_15420 3af8da9182bcc37968450382e3525470 482 PRINTS PR00982 Lysyl-tRNA synthetase signature 243 260 2.5E-31 T 14-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MB46_15420 3af8da9182bcc37968450382e3525470 482 PRINTS PR00982 Lysyl-tRNA synthetase signature 225 238 2.5E-31 T 14-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MB46_15420 3af8da9182bcc37968450382e3525470 482 SUPERFAMILY SSF55681 143 480 1.44E-94 T 14-10-2018 MB46_15420 3af8da9182bcc37968450382e3525470 482 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 3 482 34.058 T 14-10-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MB46_15420 3af8da9182bcc37968450382e3525470 482 Gene3D G3DSA:3.30.930.10 142 482 9.1E-104 T 14-10-2018 MB46_15420 3af8da9182bcc37968450382e3525470 482 Gene3D G3DSA:2.40.50.140 1 137 3.5E-36 T 14-10-2018 MB46_15420 3af8da9182bcc37968450382e3525470 482 Pfam PF00152 tRNA synthetases class II (D, K and N) 143 479 6.9E-63 T 14-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 MB46_15420 3af8da9182bcc37968450382e3525470 482 SUPERFAMILY SSF50249 2 136 6.37E-33 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold MB46_00680 585fd93405c8f0be67eb7496c3bf3666 297 Pfam PF13845 Septum formation 75 268 1.2E-17 T 14-10-2018 IPR026004 Septum formation-related domain MB46_07665 dbaffeaf59c6ec210b593befe06533c1 214 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 5 189 6.5E-25 T 14-10-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type MB46_07665 dbaffeaf59c6ec210b593befe06533c1 214 TIGRFAM TIGR03085 TIGR03085: TIGR03085 family protein 6 207 4.6E-68 T 14-10-2018 IPR017519 Conserved hypothetical protein CHP03085 MB46_15205 7b88f75cc0d825a66281376232661dd1 110 Pfam PF01910 Thiamine-binding protein 4 101 2.8E-27 T 14-10-2018 IPR002767 Thiamine-binding protein MB46_15205 7b88f75cc0d825a66281376232661dd1 110 Gene3D G3DSA:3.30.70.930 1 107 1.4E-23 T 14-10-2018 IPR029756 MTH1187/YkoF-like MB46_15205 7b88f75cc0d825a66281376232661dd1 110 SUPERFAMILY SSF89957 2 106 5.89E-25 T 14-10-2018 IPR029756 MTH1187/YkoF-like MB46_03905 a78ed9b7656795e366aef3db65e1d9de 73 Pfam PF11248 Protein of unknown function (DUF3046) 1 61 1.1E-23 T 14-10-2018 IPR021408 Protein of unknown function DUF3046 MB46_13420 5e9839287cd6021b72f197fd24f74dd8 279 Gene3D G3DSA:2.40.50.140 1 115 7.0E-47 T 14-10-2018 MB46_13420 5e9839287cd6021b72f197fd24f74dd8 279 Gene3D G3DSA:2.30.30.30 119 196 9.9E-33 T 14-10-2018 IPR014722 Ribosomal protein L2, domain 2 MB46_13420 5e9839287cd6021b72f197fd24f74dd8 279 PIRSF PIRSF002158 3 275 1.6E-93 T 14-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MB46_13420 5e9839287cd6021b72f197fd24f74dd8 279 Gene3D G3DSA:4.10.950.10 197 274 2.2E-29 T 14-10-2018 IPR014726 Ribosomal protein L2, domain 3 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MB46_13420 5e9839287cd6021b72f197fd24f74dd8 279 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 3 273 3.2E-126 T 14-10-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 MB46_13420 5e9839287cd6021b72f197fd24f74dd8 279 SUPERFAMILY SSF50249 3 126 6.17E-49 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold MB46_13420 5e9839287cd6021b72f197fd24f74dd8 279 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 118 1.7E-33 T 14-10-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 MB46_13420 5e9839287cd6021b72f197fd24f74dd8 279 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 126 251 1.6E-54 T 14-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 MB46_13420 5e9839287cd6021b72f197fd24f74dd8 279 ProSitePatterns PS00467 Ribosomal protein L2 signature. 219 230 - T 14-10-2018 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MB46_13420 5e9839287cd6021b72f197fd24f74dd8 279 SMART SM01382 125 253 8.0E-88 T 14-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 MB46_13420 5e9839287cd6021b72f197fd24f74dd8 279 SUPERFAMILY SSF50104 127 271 5.66E-55 T 14-10-2018 IPR008991 Translation protein SH3-like domain superfamily MB46_13420 5e9839287cd6021b72f197fd24f74dd8 279 SMART SM01383 42 119 1.7E-41 T 14-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MB46_13420 5e9839287cd6021b72f197fd24f74dd8 279 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 273 47.047 T 14-10-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 MB46_06570 f747911f904f2c58459ae46cb315f7c2 193 SUPERFAMILY SSF46689 6 84 4.82E-17 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MB46_06570 f747911f904f2c58459ae46cb315f7c2 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 1.6E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MB46_06570 f747911f904f2c58459ae46cb315f7c2 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 1.6E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MB46_06570 f747911f904f2c58459ae46cb315f7c2 193 Gene3D G3DSA:1.10.357.10 3 193 1.9E-49 T 14-10-2018 MB46_06570 f747911f904f2c58459ae46cb315f7c2 193 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 60 4.1E-14 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MB46_06570 f747911f904f2c58459ae46cb315f7c2 193 SUPERFAMILY SSF48498 87 185 1.33E-7 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily MB46_14125 29a008699273afc1505373863078d397 464 SUPERFAMILY SSF51905 4 320 4.88E-48 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_14125 29a008699273afc1505373863078d397 464 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 322 2.1E-58 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MB46_14125 29a008699273afc1505373863078d397 464 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 431 451 1.6E-48 T 14-10-2018 MB46_14125 29a008699273afc1505373863078d397 464 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 262 276 1.6E-48 T 14-10-2018 MB46_14125 29a008699273afc1505373863078d397 464 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 344 365 1.6E-48 T 14-10-2018 MB46_14125 29a008699273afc1505373863078d397 464 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 177 202 1.6E-48 T 14-10-2018 MB46_14125 29a008699273afc1505373863078d397 464 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 39 54 1.6E-48 T 14-10-2018 MB46_14125 29a008699273afc1505373863078d397 464 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 305 312 1.6E-48 T 14-10-2018 MB46_14125 29a008699273afc1505373863078d397 464 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 141 150 1.6E-48 T 14-10-2018 MB46_14125 29a008699273afc1505373863078d397 464 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 409 424 1.6E-48 T 14-10-2018 MB46_14125 29a008699273afc1505373863078d397 464 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 1.6E-48 T 14-10-2018 MB46_14125 29a008699273afc1505373863078d397 464 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 1.6E-26 T 14-10-2018 MB46_14125 29a008699273afc1505373863078d397 464 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 261 277 1.6E-26 T 14-10-2018 MB46_14125 29a008699273afc1505373863078d397 464 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 138 156 1.6E-26 T 14-10-2018 MB46_14125 29a008699273afc1505373863078d397 464 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 290 312 1.6E-26 T 14-10-2018 MB46_14125 29a008699273afc1505373863078d397 464 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 177 195 1.6E-26 T 14-10-2018 MB46_14125 29a008699273afc1505373863078d397 464 Gene3D G3DSA:3.30.390.30 346 463 1.2E-30 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 MB46_14125 29a008699273afc1505373863078d397 464 Gene3D G3DSA:3.50.50.60 6 329 9.3E-102 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_14125 29a008699273afc1505373863078d397 464 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 348 454 8.2E-25 T 14-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 MB46_14125 29a008699273afc1505373863078d397 464 PIRSF PIRSF000350 2 461 9.5E-97 T 14-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 MB46_14125 29a008699273afc1505373863078d397 464 SUPERFAMILY SSF55424 346 459 1.39E-30 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 MB46_14125 29a008699273afc1505373863078d397 464 Gene3D G3DSA:3.50.50.60 157 275 9.3E-102 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_04410 2ba10006d3fe0182ffbc89de35053a61 518 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 102 440 2.9E-61 T 14-10-2018 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 MB46_04410 2ba10006d3fe0182ffbc89de35053a61 518 SUPERFAMILY SSF53383 57 507 9.18E-117 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MB46_04410 2ba10006d3fe0182ffbc89de35053a61 518 Gene3D G3DSA:3.40.640.10 130 383 1.4E-124 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MB46_04410 2ba10006d3fe0182ffbc89de35053a61 518 Gene3D G3DSA:3.90.1150.170 62 500 1.4E-124 T 14-10-2018 MB46_09615 7dc5d927ce092f103f503f63eaa73550 524 SMART SM00963 1 86 1.6E-34 T 14-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MB46_09615 7dc5d927ce092f103f503f63eaa73550 524 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 5 447 33.573 T 14-10-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 MB46_09615 7dc5d927ce092f103f503f63eaa73550 524 Gene3D G3DSA:1.20.120.140 5 314 5.8E-120 T 14-10-2018 MB46_09615 7dc5d927ce092f103f503f63eaa73550 524 SMART SM00382 99 309 2.4E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_09615 7dc5d927ce092f103f503f63eaa73550 524 SUPERFAMILY SSF47446 336 437 6.38E-34 T 14-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 MB46_09615 7dc5d927ce092f103f503f63eaa73550 524 Pfam PF02881 SRP54-type protein, helical bundle domain 5 82 2.2E-22 T 14-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MB46_09615 7dc5d927ce092f103f503f63eaa73550 524 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 277 290 - T 14-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MB46_09615 7dc5d927ce092f103f503f63eaa73550 524 Pfam PF00448 SRP54-type protein, GTPase domain 100 303 1.1E-69 T 14-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MB46_09615 7dc5d927ce092f103f503f63eaa73550 524 SUPERFAMILY SSF52540 42 363 1.59E-57 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_09615 7dc5d927ce092f103f503f63eaa73550 524 SMART SM00962 100 304 2.9E-108 T 14-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MB46_09615 7dc5d927ce092f103f503f63eaa73550 524 Pfam PF02978 Signal peptide binding domain 337 434 1.1E-30 T 14-10-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 MB46_09615 7dc5d927ce092f103f503f63eaa73550 524 Gene3D G3DSA:1.10.260.30 336 456 3.3E-41 T 14-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 MB46_09615 7dc5d927ce092f103f503f63eaa73550 524 TIGRFAM TIGR00959 ffh: signal recognition particle protein 2 436 4.9E-174 T 14-10-2018 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 MB46_09615 7dc5d927ce092f103f503f63eaa73550 524 Gene3D G3DSA:3.40.50.300 90 293 5.8E-120 T 14-10-2018 MB46_08470 45390d61fb70c91d487a779697fc6801 288 SUPERFAMILY SSF51366 17 280 1.97E-58 T 14-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 MB46_08470 45390d61fb70c91d487a779697fc6801 288 Hamap MF_01215 Orotidine 5'-phosphate decarboxylase [pyrF]. 15 287 31.6 T 14-10-2018 IPR011995 Orotidine 5'-phosphate decarboxylase, type 2 GO:0004590|GO:0006221 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MB46_08470 45390d61fb70c91d487a779697fc6801 288 Gene3D G3DSA:3.20.20.70 16 287 1.7E-82 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MB46_08470 45390d61fb70c91d487a779697fc6801 288 TIGRFAM TIGR02127 pyrF_sub2: orotidine 5'-phosphate decarboxylase 17 280 5.7E-79 T 14-10-2018 IPR011995 Orotidine 5'-phosphate decarboxylase, type 2 GO:0004590|GO:0006221 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MB46_08470 45390d61fb70c91d487a779697fc6801 288 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 30 275 2.6E-31 T 14-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MB46_08470 45390d61fb70c91d487a779697fc6801 288 SMART SM00934 30 280 5.2E-28 T 14-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MB46_14305 840f8271b1911b356842c9f8221937cc 233 Gene3D G3DSA:3.40.50.150 19 230 2.7E-64 T 14-10-2018 MB46_14305 840f8271b1911b356842c9f8221937cc 233 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 14 229 2.7E-74 T 14-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 MB46_14305 840f8271b1911b356842c9f8221937cc 233 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 4 229 35.692 T 14-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 MB46_14305 840f8271b1911b356842c9f8221937cc 233 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 137 151 - T 14-10-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 MB46_14305 840f8271b1911b356842c9f8221937cc 233 SUPERFAMILY SSF53335 5 226 2.46E-51 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MB46_14305 840f8271b1911b356842c9f8221937cc 233 Pfam PF01209 ubiE/COQ5 methyltransferase family 12 229 2.1E-65 T 14-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 MB46_18120 91eb547196b8d1cc34c05b59e74c87e0 119 Pfam PF03551 Transcriptional regulator PadR-like family 8 81 3.5E-17 T 14-10-2018 IPR005149 Transcription regulator PadR, N-terminal MB46_18120 91eb547196b8d1cc34c05b59e74c87e0 119 SUPERFAMILY SSF46785 5 88 6.0E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_18120 91eb547196b8d1cc34c05b59e74c87e0 119 Gene3D G3DSA:1.10.10.10 1 98 3.6E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_19040 dca1cc7d7b42d45b74d5349b9fbf2705 248 TIGRFAM TIGR01258 pgm_1: phosphoglycerate mutase 1 family 4 247 4.5E-108 T 14-10-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 MB46_19040 dca1cc7d7b42d45b74d5349b9fbf2705 248 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 141 208 6.3E-5 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MB46_19040 dca1cc7d7b42d45b74d5349b9fbf2705 248 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 5 124 1.6E-26 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MB46_19040 dca1cc7d7b42d45b74d5349b9fbf2705 248 Gene3D G3DSA:3.40.50.1240 2 248 2.5E-80 T 14-10-2018 IPR029033 Histidine phosphatase superfamily MB46_19040 dca1cc7d7b42d45b74d5349b9fbf2705 248 SMART SM00855 4 189 5.5E-23 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MB46_19040 dca1cc7d7b42d45b74d5349b9fbf2705 248 SUPERFAMILY SSF53254 1 221 5.14E-70 T 14-10-2018 IPR029033 Histidine phosphatase superfamily MB46_19040 dca1cc7d7b42d45b74d5349b9fbf2705 248 Hamap MF_01039 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [gpmA]. 2 230 41.069 T 14-10-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 MB46_19040 dca1cc7d7b42d45b74d5349b9fbf2705 248 PIRSF PIRSF000709 141 223 0.13 T 14-10-2018 MB46_19040 dca1cc7d7b42d45b74d5349b9fbf2705 248 PIRSF PIRSF000709 3 113 0.0037 T 14-10-2018 MB46_06085 9c0aec30a723a3627730254b9e6efd54 250 Pfam PF07729 FCD domain 104 227 2.1E-16 T 14-10-2018 IPR011711 GntR, C-terminal MB46_06085 9c0aec30a723a3627730254b9e6efd54 250 Gene3D G3DSA:1.20.120.530 102 232 2.6E-21 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MB46_06085 9c0aec30a723a3627730254b9e6efd54 250 SUPERFAMILY SSF46785 14 90 7.39E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_06085 9c0aec30a723a3627730254b9e6efd54 250 SMART SM00895 104 231 7.0E-17 T 14-10-2018 IPR011711 GntR, C-terminal MB46_06085 9c0aec30a723a3627730254b9e6efd54 250 SUPERFAMILY SSF48008 102 230 7.06E-20 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MB46_06085 9c0aec30a723a3627730254b9e6efd54 250 SMART SM00345 18 79 2.0E-17 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MB46_06085 9c0aec30a723a3627730254b9e6efd54 250 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 73 1.4E-20 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MB46_06085 9c0aec30a723a3627730254b9e6efd54 250 Gene3D G3DSA:1.10.10.10 12 78 9.0E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_06085 9c0aec30a723a3627730254b9e6efd54 250 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 37 51 6.9E-11 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MB46_06085 9c0aec30a723a3627730254b9e6efd54 250 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 51 67 6.9E-11 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MB46_05135 5bdefa45190a2d57d3b1e3f769561d4a 491 Pfam PF01458 Uncharacterized protein family (UPF0051) 237 462 2.6E-76 T 14-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 MB46_05135 5bdefa45190a2d57d3b1e3f769561d4a 491 TIGRFAM TIGR01980 sufB: FeS assembly protein SufB 35 482 1.4E-220 T 14-10-2018 IPR010231 SUF system FeS cluster assembly, SufB GO:0016226 MB46_05135 5bdefa45190a2d57d3b1e3f769561d4a 491 SUPERFAMILY SSF101960 57 488 1.31E-140 T 14-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily MB46_18670 c63827c880b02ef6d03f1406ab8b9e58 205 SUPERFAMILY SSF53041 9 144 3.14E-36 T 14-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 MB46_18670 c63827c880b02ef6d03f1406ab8b9e58 205 Pfam PF00239 Resolvase, N terminal domain 10 144 6.5E-35 T 14-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 MB46_18670 c63827c880b02ef6d03f1406ab8b9e58 205 SUPERFAMILY SSF46689 147 186 8.24E-7 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MB46_18670 c63827c880b02ef6d03f1406ab8b9e58 205 SMART SM00857 10 144 1.3E-41 T 14-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 MB46_18670 c63827c880b02ef6d03f1406ab8b9e58 205 Gene3D G3DSA:3.40.50.1390 9 132 3.4E-35 T 14-10-2018 MB46_18670 c63827c880b02ef6d03f1406ab8b9e58 205 ProSitePatterns PS00397 Site-specific recombinases active site. 13 21 - T 14-10-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 MB46_18670 c63827c880b02ef6d03f1406ab8b9e58 205 Pfam PF02796 Helix-turn-helix domain of resolvase 148 182 2.6E-6 T 14-10-2018 IPR006120 Resolvase, HTH domain GO:0000150|GO:0003677|GO:0006310 MB46_18670 c63827c880b02ef6d03f1406ab8b9e58 205 Gene3D G3DSA:1.10.10.10 143 200 3.9E-6 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_08575 87e196e4d80e0a60651d27d4e5bc38a1 478 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 38 166 4.9E-14 T 14-10-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 MB46_08575 87e196e4d80e0a60651d27d4e5bc38a1 478 Gene3D G3DSA:1.20.272.10 276 379 3.9E-47 T 14-10-2018 MB46_08575 87e196e4d80e0a60651d27d4e5bc38a1 478 SUPERFAMILY SSF48019 287 471 1.13E-72 T 14-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 MB46_08575 87e196e4d80e0a60651d27d4e5bc38a1 478 Gene3D G3DSA:1.10.3710.10 380 475 2.3E-23 T 14-10-2018 MB46_08575 87e196e4d80e0a60651d27d4e5bc38a1 478 Pfam PF16193 AAA C-terminal domain 216 301 1.1E-26 T 14-10-2018 IPR032423 AAA C-terminal domain MB46_08575 87e196e4d80e0a60651d27d4e5bc38a1 478 Gene3D G3DSA:3.40.50.300 27 191 1.8E-35 T 14-10-2018 MB46_08575 87e196e4d80e0a60651d27d4e5bc38a1 478 Pfam PF12002 MgsA AAA+ ATPase C terminal 302 467 5.4E-68 T 14-10-2018 IPR021886 MgsA AAA+ ATPase C-terminal MB46_08575 87e196e4d80e0a60651d27d4e5bc38a1 478 SUPERFAMILY SSF52540 33 260 3.62E-39 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_08575 87e196e4d80e0a60651d27d4e5bc38a1 478 SMART SM00382 76 197 6.6E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_08575 87e196e4d80e0a60651d27d4e5bc38a1 478 Gene3D G3DSA:1.10.8.60 193 261 9.2E-12 T 14-10-2018 MB46_05735 28841e39cffceb10be5ff0db5701c179 437 Gene3D G3DSA:3.40.190.10 57 357 2.7E-103 T 14-10-2018 MB46_05735 28841e39cffceb10be5ff0db5701c179 437 Gene3D G3DSA:3.40.190.10 151 413 2.7E-103 T 14-10-2018 MB46_05735 28841e39cffceb10be5ff0db5701c179 437 SUPERFAMILY SSF53850 21 423 4.98E-67 T 14-10-2018 MB46_05735 28841e39cffceb10be5ff0db5701c179 437 Pfam PF01547 Bacterial extracellular solute-binding protein 54 335 9.0E-37 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein MB46_12705 e0fca85c7637664c378d0febfd185f0a 308 SUPERFAMILY SSF53067 15 115 5.18E-5 T 14-10-2018 MB46_12705 e0fca85c7637664c378d0febfd185f0a 308 Gene3D G3DSA:3.30.420.40 117 287 4.2E-63 T 14-10-2018 MB46_12705 e0fca85c7637664c378d0febfd185f0a 308 Gene3D G3DSA:3.30.420.40 15 294 4.2E-63 T 14-10-2018 MB46_12705 e0fca85c7637664c378d0febfd185f0a 308 SUPERFAMILY SSF53067 119 299 1.3E-42 T 14-10-2018 MB46_12705 e0fca85c7637664c378d0febfd185f0a 308 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 16 278 1.1E-17 T 14-10-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 MB46_04690 f20808f73451c9dc7a56a158ffd81b04 334 PRINTS PR01577 KCNAB voltage-gated K+ channel beta subunit family signature 271 284 3.1E-6 T 14-10-2018 IPR005399 Potassium channel, voltage-dependent, beta subunit, KCNAB-related Reactome: R-HSA-1296072 MB46_04690 f20808f73451c9dc7a56a158ffd81b04 334 PRINTS PR01577 KCNAB voltage-gated K+ channel beta subunit family signature 258 270 3.1E-6 T 14-10-2018 IPR005399 Potassium channel, voltage-dependent, beta subunit, KCNAB-related Reactome: R-HSA-1296072 MB46_04690 f20808f73451c9dc7a56a158ffd81b04 334 PRINTS PR01577 KCNAB voltage-gated K+ channel beta subunit family signature 204 210 3.1E-6 T 14-10-2018 IPR005399 Potassium channel, voltage-dependent, beta subunit, KCNAB-related Reactome: R-HSA-1296072 MB46_04690 f20808f73451c9dc7a56a158ffd81b04 334 PRINTS PR01577 KCNAB voltage-gated K+ channel beta subunit family signature 110 120 3.1E-6 T 14-10-2018 IPR005399 Potassium channel, voltage-dependent, beta subunit, KCNAB-related Reactome: R-HSA-1296072 MB46_04690 f20808f73451c9dc7a56a158ffd81b04 334 Pfam PF00248 Aldo/keto reductase family 15 314 7.2E-68 T 14-10-2018 IPR023210 NADP-dependent oxidoreductase domain MB46_04690 f20808f73451c9dc7a56a158ffd81b04 334 SUPERFAMILY SSF51430 1 315 6.02E-94 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily MB46_04690 f20808f73451c9dc7a56a158ffd81b04 334 Gene3D G3DSA:3.20.20.100 1 328 3.7E-108 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily MB46_18345 0e0d3a3cf888dc6989cf99f8469cdb30 284 Gene3D G3DSA:1.10.10.10 13 83 6.8E-15 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_18345 0e0d3a3cf888dc6989cf99f8469cdb30 284 SUPERFAMILY SSF53697 106 254 3.03E-20 T 14-10-2018 MB46_18345 0e0d3a3cf888dc6989cf99f8469cdb30 284 Gene3D G3DSA:3.40.50.10490 99 280 6.5E-29 T 14-10-2018 MB46_18345 0e0d3a3cf888dc6989cf99f8469cdb30 284 Pfam PF01418 Helix-turn-helix domain, rpiR family 16 78 3.2E-14 T 14-10-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 MB46_18345 0e0d3a3cf888dc6989cf99f8469cdb30 284 SUPERFAMILY SSF46689 18 79 1.18E-12 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MB46_18345 0e0d3a3cf888dc6989cf99f8469cdb30 284 Pfam PF01380 SIS domain 130 253 1.0E-8 T 14-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 MB46_13710 64661970e0bc5842ec7611febd0fce39 363 PIRSF PIRSF015921 3 350 2.8E-69 T 14-10-2018 IPR012171 Fatty acid desaturase GO:0006629|GO:0016021|GO:0016491 MB46_13710 64661970e0bc5842ec7611febd0fce39 363 Pfam PF00487 Fatty acid desaturase 67 326 2.7E-41 T 14-10-2018 IPR005804 Fatty acid desaturase domain GO:0006629 MB46_03130 74893812b6bba80aaf2f52aebdc0bf16 301 Gene3D G3DSA:3.40.50.10490 163 288 2.5E-15 T 14-10-2018 MB46_03130 74893812b6bba80aaf2f52aebdc0bf16 301 SUPERFAMILY SSF53697 3 297 1.11E-41 T 14-10-2018 MB46_03130 74893812b6bba80aaf2f52aebdc0bf16 301 Gene3D G3DSA:3.40.50.10490 13 162 4.0E-24 T 14-10-2018 MB46_03130 74893812b6bba80aaf2f52aebdc0bf16 301 Pfam PF01380 SIS domain 41 155 7.4E-7 T 14-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 MB46_11150 0b623184f08305bbd8a335194d30f653 388 SUPERFAMILY SSF55347 131 285 1.8E-33 T 14-10-2018 MB46_11150 0b623184f08305bbd8a335194d30f653 388 Gene3D G3DSA:3.30.360.10 138 363 1.3E-42 T 14-10-2018 MB46_11150 0b623184f08305bbd8a335194d30f653 388 SUPERFAMILY SSF51735 2 176 1.36E-35 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_11150 0b623184f08305bbd8a335194d30f653 388 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 139 243 5.1E-10 T 14-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 MB46_11150 0b623184f08305bbd8a335194d30f653 388 Gene3D G3DSA:3.40.50.720 1 137 4.9E-28 T 14-10-2018 MB46_11150 0b623184f08305bbd8a335194d30f653 388 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 6 118 9.8E-14 T 14-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 MB46_07315 fffddb4facedf6fc2ebf4b73de0dc55c 260 Pfam PF02517 CAAX protease self-immunity 146 244 6.3E-9 T 14-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 MB46_11520 bae1d1ba989e5b916d0383066e34852c 198 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 108 142 1.1E-5 T 14-10-2018 IPR001451 Hexapeptide repeat MB46_11520 bae1d1ba989e5b916d0383066e34852c 198 Gene3D G3DSA:2.160.10.10 2 158 2.5E-39 T 14-10-2018 MB46_11520 bae1d1ba989e5b916d0383066e34852c 198 SUPERFAMILY SSF51161 2 161 1.26E-42 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily MB46_11520 bae1d1ba989e5b916d0383066e34852c 198 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 50 84 6.2E-7 T 14-10-2018 IPR001451 Hexapeptide repeat MB46_11520 bae1d1ba989e5b916d0383066e34852c 198 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 15 47 1.2E-6 T 14-10-2018 IPR001451 Hexapeptide repeat MB46_14240 890b51e8e48639c5bbab87475a0e471d 458 PRINTS PR00315 GTP-binding elongation factor signature 118 129 1.2E-8 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MB46_14240 890b51e8e48639c5bbab87475a0e471d 458 PRINTS PR00315 GTP-binding elongation factor signature 155 164 1.2E-8 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MB46_14240 890b51e8e48639c5bbab87475a0e471d 458 PRINTS PR00315 GTP-binding elongation factor signature 16 29 1.2E-8 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MB46_14240 890b51e8e48639c5bbab87475a0e471d 458 PRINTS PR00315 GTP-binding elongation factor signature 102 112 1.2E-8 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MB46_14240 890b51e8e48639c5bbab87475a0e471d 458 Gene3D G3DSA:2.40.30.10 234 338 1.2E-21 T 14-10-2018 MB46_14240 890b51e8e48639c5bbab87475a0e471d 458 TIGRFAM TIGR02034 CysN: sulfate adenylyltransferase, large subunit 16 444 5.3E-149 T 14-10-2018 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 MB46_14240 890b51e8e48639c5bbab87475a0e471d 458 Gene3D G3DSA:2.40.30.10 342 445 1.1E-26 T 14-10-2018 MB46_14240 890b51e8e48639c5bbab87475a0e471d 458 SUPERFAMILY SSF50447 237 338 3.53E-14 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily MB46_14240 890b51e8e48639c5bbab87475a0e471d 458 SUPERFAMILY SSF50465 342 444 8.15E-26 T 14-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal MB46_14240 890b51e8e48639c5bbab87475a0e471d 458 Gene3D G3DSA:3.40.50.300 7 230 1.7E-65 T 14-10-2018 MB46_14240 890b51e8e48639c5bbab87475a0e471d 458 SUPERFAMILY SSF52540 14 227 1.29E-52 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_14240 890b51e8e48639c5bbab87475a0e471d 458 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 75 90 - T 14-10-2018 IPR031157 Tr-type G domain, conserved site MB46_14240 890b51e8e48639c5bbab87475a0e471d 458 Pfam PF00009 Elongation factor Tu GTP binding domain 16 218 6.5E-40 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MB46_15120 e64b6585d1c553b231455b6be09a87f7 486 Gene3D G3DSA:3.90.1720.10 259 480 3.7E-37 T 14-10-2018 MB46_15120 e64b6585d1c553b231455b6be09a87f7 486 Pfam PF00877 NlpC/P60 family 378 464 1.1E-21 T 14-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain MB46_15120 e64b6585d1c553b231455b6be09a87f7 486 SUPERFAMILY SSF54001 357 473 4.9E-33 T 14-10-2018 IPR038765 Papain-like cysteine peptidase superfamily MB46_03365 9dfe634575de2d6cada21f2e8cc46f69 216 Pfam PF01066 CDP-alcohol phosphatidyltransferase 18 82 1.7E-16 T 14-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 MB46_03365 9dfe634575de2d6cada21f2e8cc46f69 216 Gene3D G3DSA:1.20.120.1760 13 193 2.6E-13 T 14-10-2018 MB46_03365 9dfe634575de2d6cada21f2e8cc46f69 216 PIRSF PIRSF000847 13 194 6.3E-41 T 14-10-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 MB46_03365 9dfe634575de2d6cada21f2e8cc46f69 216 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 60 82 - T 14-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 MB46_07060 91324d67d5fcbe4cc79a97ea08a85b72 242 Gene3D G3DSA:1.10.10.10 10 85 1.3E-16 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_07060 91324d67d5fcbe4cc79a97ea08a85b72 242 SUPERFAMILY SSF55781 79 239 2.16E-23 T 14-10-2018 MB46_07060 91324d67d5fcbe4cc79a97ea08a85b72 242 SUPERFAMILY SSF46785 18 88 7.59E-15 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_07060 91324d67d5fcbe4cc79a97ea08a85b72 242 Pfam PF09339 IclR helix-turn-helix domain 19 69 3.4E-12 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 MB46_07060 91324d67d5fcbe4cc79a97ea08a85b72 242 Gene3D G3DSA:3.30.450.40 87 242 1.2E-19 T 14-10-2018 IPR029016 GAF-like domain superfamily MB46_07060 91324d67d5fcbe4cc79a97ea08a85b72 242 SMART SM00346 17 104 8.3E-12 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 MB46_09800 470ebc023c6dcedc6c83b9f4a5c2e74e 468 Gene3D G3DSA:3.30.479.30 79 192 1.2E-27 T 14-10-2018 MB46_09800 470ebc023c6dcedc6c83b9f4a5c2e74e 468 Pfam PF01145 SPFH domain / Band 7 family 34 217 1.2E-22 T 14-10-2018 IPR001107 Band 7 domain MB46_09800 470ebc023c6dcedc6c83b9f4a5c2e74e 468 SUPERFAMILY SSF117892 70 207 5.49E-30 T 14-10-2018 IPR036013 Band 7/SPFH domain superfamily MB46_09800 470ebc023c6dcedc6c83b9f4a5c2e74e 468 Pfam PF15975 Flotillin 352 428 3.7E-10 T 14-10-2018 IPR031905 Flotillin, C-terminal domain Reactome: R-HSA-8849932 MB46_09800 470ebc023c6dcedc6c83b9f4a5c2e74e 468 SMART SM00244 30 203 3.1E-7 T 14-10-2018 IPR001107 Band 7 domain MB46_18940 56d191b0e61f71de36dce7c2b6e8aa29 1583 PRINTS PR01607 Apyrase family signature 1261 1284 1.5E-18 T 14-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MB46_18940 56d191b0e61f71de36dce7c2b6e8aa29 1583 PRINTS PR01607 Apyrase family signature 1340 1359 1.5E-18 T 14-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MB46_18940 56d191b0e61f71de36dce7c2b6e8aa29 1583 PRINTS PR01607 Apyrase family signature 1039 1056 1.5E-18 T 14-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MB46_18940 56d191b0e61f71de36dce7c2b6e8aa29 1583 PRINTS PR01607 Apyrase family signature 1113 1133 1.5E-18 T 14-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MB46_18940 56d191b0e61f71de36dce7c2b6e8aa29 1583 PRINTS PR01607 Apyrase family signature 870 888 1.5E-18 T 14-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MB46_18940 56d191b0e61f71de36dce7c2b6e8aa29 1583 Gene3D G3DSA:3.60.10.10 537 860 3.3E-39 T 14-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily MB46_18940 56d191b0e61f71de36dce7c2b6e8aa29 1583 Gene3D G3DSA:3.60.21.10 870 1171 4.5E-68 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like MB46_18940 56d191b0e61f71de36dce7c2b6e8aa29 1583 SUPERFAMILY SSF55816 1204 1393 4.45E-42 T 14-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MB46_18940 56d191b0e61f71de36dce7c2b6e8aa29 1583 SUPERFAMILY SSF74853 65 176 8.63E-9 T 14-10-2018 IPR036415 Lamin tail domain superfamily MB46_18940 56d191b0e61f71de36dce7c2b6e8aa29 1583 SUPERFAMILY SSF56300 867 1153 4.02E-61 T 14-10-2018 MB46_18940 56d191b0e61f71de36dce7c2b6e8aa29 1583 Pfam PF02872 5'-nucleotidase, C-terminal domain 1200 1366 3.6E-34 T 14-10-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MB46_18940 56d191b0e61f71de36dce7c2b6e8aa29 1583 SUPERFAMILY SSF56219 534 863 1.44E-28 T 14-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily MB46_18940 56d191b0e61f71de36dce7c2b6e8aa29 1583 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 541 822 1.0E-8 T 14-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase MB46_18940 56d191b0e61f71de36dce7c2b6e8aa29 1583 Pfam PF00149 Calcineurin-like phosphoesterase 874 1093 4.2E-4 T 14-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 MB46_18940 56d191b0e61f71de36dce7c2b6e8aa29 1583 Gene3D G3DSA:3.90.780.10 1200 1402 1.8E-50 T 14-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MB46_18940 56d191b0e61f71de36dce7c2b6e8aa29 1583 Pfam PF00932 Lamin Tail Domain 67 200 1.0E-14 T 14-10-2018 IPR001322 Lamin tail domain MB46_06540 2135ba1cf5b9a7bc68a4f871d9b3f56a 313 PRINTS PR00990 Ribokinase signature 217 228 7.4E-5 T 14-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 MB46_06540 2135ba1cf5b9a7bc68a4f871d9b3f56a 313 PRINTS PR00990 Ribokinase signature 33 52 7.4E-5 T 14-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 MB46_06540 2135ba1cf5b9a7bc68a4f871d9b3f56a 313 PRINTS PR00990 Ribokinase signature 178 193 7.4E-5 T 14-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 MB46_06540 2135ba1cf5b9a7bc68a4f871d9b3f56a 313 Gene3D G3DSA:3.40.1190.20 12 303 4.8E-66 T 14-10-2018 IPR029056 Ribokinase-like MB46_06540 2135ba1cf5b9a7bc68a4f871d9b3f56a 313 SUPERFAMILY SSF53613 15 305 4.68E-59 T 14-10-2018 IPR029056 Ribokinase-like MB46_06540 2135ba1cf5b9a7bc68a4f871d9b3f56a 313 Pfam PF00294 pfkB family carbohydrate kinase 15 298 4.3E-39 T 14-10-2018 IPR011611 Carbohydrate kinase PfkB MB46_06540 2135ba1cf5b9a7bc68a4f871d9b3f56a 313 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 246 259 - T 14-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 MB46_06540 2135ba1cf5b9a7bc68a4f871d9b3f56a 313 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 38 62 - T 14-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 MB46_17435 12e9abc56b7bd09365c2ad2a2b5ae098 297 Pfam PF00581 Rhodanese-like domain 139 220 2.3E-4 T 14-10-2018 IPR001763 Rhodanese-like domain MB46_17435 12e9abc56b7bd09365c2ad2a2b5ae098 297 Gene3D G3DSA:3.30.70.100 1 96 1.7E-23 T 14-10-2018 MB46_17435 12e9abc56b7bd09365c2ad2a2b5ae098 297 SUPERFAMILY SSF52821 114 221 2.88E-21 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily MB46_17435 12e9abc56b7bd09365c2ad2a2b5ae098 297 Hamap MF_00469 UPF0176 protein YceA [yceA]. 2 264 36.412 T 14-10-2018 IPR020936 Uncharacterised protein family UPF0176 MB46_17435 12e9abc56b7bd09365c2ad2a2b5ae098 297 SMART SM00450 123 225 1.0E-12 T 14-10-2018 IPR001763 Rhodanese-like domain MB46_17435 12e9abc56b7bd09365c2ad2a2b5ae098 297 Gene3D G3DSA:3.40.250.10 109 259 2.8E-37 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily MB46_17435 12e9abc56b7bd09365c2ad2a2b5ae098 297 Pfam PF12368 Rhodanase C-terminal 230 295 4.6E-16 T 14-10-2018 IPR022111 Rhodanase, C-terminal MB46_13875 88a5e6f664256f3c47f73c3a4cfd26f7 228 Pfam PF01476 LysM domain 180 227 3.0E-7 T 14-10-2018 IPR018392 LysM domain MB46_13875 88a5e6f664256f3c47f73c3a4cfd26f7 228 SMART SM00257 179 227 0.0012 T 14-10-2018 IPR018392 LysM domain MB46_13875 88a5e6f664256f3c47f73c3a4cfd26f7 228 Gene3D G3DSA:3.10.350.10 178 225 1.2E-8 T 14-10-2018 IPR036779 LysM domain superfamily MB46_13875 88a5e6f664256f3c47f73c3a4cfd26f7 228 Gene3D G3DSA:1.10.530.10 16 113 1.3E-34 T 14-10-2018 MB46_13875 88a5e6f664256f3c47f73c3a4cfd26f7 228 SUPERFAMILY SSF53955 34 112 7.16E-30 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily MB46_13875 88a5e6f664256f3c47f73c3a4cfd26f7 228 SUPERFAMILY SSF54106 179 227 4.19E-5 T 14-10-2018 MB46_13875 88a5e6f664256f3c47f73c3a4cfd26f7 228 Pfam PF06737 Transglycosylase-like domain 34 106 3.9E-30 T 14-10-2018 IPR010618 Transglycosylase-like MB46_01835 ce4238329da157714fe7a983018e0d07 286 Hamap MF_01927 Formyltetrahydrofolate deformylase [purU]. 7 285 45.718 T 14-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 MB46_01835 ce4238329da157714fe7a983018e0d07 286 Gene3D G3DSA:3.40.50.170 91 286 9.6E-69 T 14-10-2018 MB46_01835 ce4238329da157714fe7a983018e0d07 286 SUPERFAMILY SSF55021 6 87 3.87E-19 T 14-10-2018 MB46_01835 ce4238329da157714fe7a983018e0d07 286 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 91 113 5.4E-49 T 14-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 MB46_01835 ce4238329da157714fe7a983018e0d07 286 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 113 140 5.4E-49 T 14-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 MB46_01835 ce4238329da157714fe7a983018e0d07 286 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 237 259 5.4E-49 T 14-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 MB46_01835 ce4238329da157714fe7a983018e0d07 286 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 259 284 5.4E-49 T 14-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 MB46_01835 ce4238329da157714fe7a983018e0d07 286 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 44 56 5.4E-49 T 14-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 MB46_01835 ce4238329da157714fe7a983018e0d07 286 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 12 38 5.4E-49 T 14-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 MB46_01835 ce4238329da157714fe7a983018e0d07 286 PIRSF PIRSF036480 7 286 2.6E-106 T 14-10-2018 MB46_01835 ce4238329da157714fe7a983018e0d07 286 Pfam PF00551 Formyl transferase 91 267 5.2E-33 T 14-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MB46_01835 ce4238329da157714fe7a983018e0d07 286 TIGRFAM TIGR00655 PurU: formyltetrahydrofolate deformylase 11 285 1.1E-98 T 14-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 MB46_01835 ce4238329da157714fe7a983018e0d07 286 SUPERFAMILY SSF53328 91 286 8.9E-59 T 14-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MB46_01835 ce4238329da157714fe7a983018e0d07 286 Gene3D G3DSA:3.30.70.260 4 87 6.5E-27 T 14-10-2018 MB46_01835 ce4238329da157714fe7a983018e0d07 286 Pfam PF13740 ACT domain 11 80 7.0E-8 T 14-10-2018 MB46_17055 99570534893f2b90357dc68b1e2f7e86 170 SMART SM00226 8 161 2.7E-36 T 14-10-2018 IPR023485 Phosphotyrosine protein phosphatase I MB46_17055 99570534893f2b90357dc68b1e2f7e86 170 SUPERFAMILY SSF52788 4 160 3.4E-42 T 14-10-2018 IPR036196 Phosphotyrosine protein phosphatase I superfamily MB46_17055 99570534893f2b90357dc68b1e2f7e86 170 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 10 27 9.9E-19 T 14-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 MB46_17055 99570534893f2b90357dc68b1e2f7e86 170 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 133 148 9.9E-19 T 14-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 MB46_17055 99570534893f2b90357dc68b1e2f7e86 170 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 51 67 9.9E-19 T 14-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 MB46_17055 99570534893f2b90357dc68b1e2f7e86 170 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 85 100 9.9E-19 T 14-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 MB46_17055 99570534893f2b90357dc68b1e2f7e86 170 Gene3D G3DSA:3.40.50.2300 3 168 1.3E-49 T 14-10-2018 MB46_17055 99570534893f2b90357dc68b1e2f7e86 170 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 10 155 1.7E-35 T 14-10-2018 IPR023485 Phosphotyrosine protein phosphatase I MB46_10650 aa5f3505c320e83f4af0743b951bad40 1034 SUPERFAMILY SSF52540 1 1027 6.29E-40 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_10650 aa5f3505c320e83f4af0743b951bad40 1034 Gene3D G3DSA:3.40.50.300 865 1031 4.6E-22 T 14-10-2018 MB46_10650 aa5f3505c320e83f4af0743b951bad40 1034 Pfam PF13558 Putative exonuclease SbcCD, C subunit 926 991 3.0E-14 T 14-10-2018 MB46_10650 aa5f3505c320e83f4af0743b951bad40 1034 Pfam PF13476 AAA domain 5 188 1.8E-21 T 14-10-2018 IPR038729 Rad50/SbcC-type AAA domain MB46_11335 ca36b8cc25bf43bf3abede4a1939e8b6 375 Pfam PF00472 RF-1 domain 230 336 5.3E-36 T 14-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 MB46_11335 ca36b8cc25bf43bf3abede4a1939e8b6 375 Gene3D G3DSA:3.30.160.20 225 319 4.2E-86 T 14-10-2018 MB46_11335 ca36b8cc25bf43bf3abede4a1939e8b6 375 SMART SM00937 84 194 1.5E-47 T 14-10-2018 IPR005139 Peptide chain release factor GO:0006415 MB46_11335 ca36b8cc25bf43bf3abede4a1939e8b6 375 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 244 260 - T 14-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 MB46_11335 ca36b8cc25bf43bf3abede4a1939e8b6 375 Gene3D G3DSA:3.30.70.1660 129 357 4.2E-86 T 14-10-2018 MB46_11335 ca36b8cc25bf43bf3abede4a1939e8b6 375 TIGRFAM TIGR00020 prfB: peptide chain release factor 2 1 363 9.8E-149 T 14-10-2018 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 MB46_11335 ca36b8cc25bf43bf3abede4a1939e8b6 375 Pfam PF03462 PCRF domain 31 219 3.7E-58 T 14-10-2018 IPR005139 Peptide chain release factor GO:0006415 MB46_11335 ca36b8cc25bf43bf3abede4a1939e8b6 375 Gene3D G3DSA:1.20.58.410 4 115 3.0E-24 T 14-10-2018 MB46_11335 ca36b8cc25bf43bf3abede4a1939e8b6 375 SUPERFAMILY SSF75620 29 366 4.97E-120 T 14-10-2018 MB46_11335 ca36b8cc25bf43bf3abede4a1939e8b6 375 Hamap MF_00094 Peptide chain release factor 2 [prfB]. 2 364 36.295 T 14-10-2018 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 MB46_06325 7e7dda4a12e7c57ec38d1e77f4db3ab0 305 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 300 7.2E-18 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_06325 7e7dda4a12e7c57ec38d1e77f4db3ab0 305 Gene3D G3DSA:1.10.3720.10 86 296 8.7E-14 T 14-10-2018 IPR035906 MetI-like superfamily MB46_06325 7e7dda4a12e7c57ec38d1e77f4db3ab0 305 SUPERFAMILY SSF161098 91 283 4.06E-18 T 14-10-2018 IPR035906 MetI-like superfamily MB46_06325 7e7dda4a12e7c57ec38d1e77f4db3ab0 305 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 33 64 5.1E-5 T 14-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain MB46_03885 83968eabeb5d00c3801ef99ccec0b502 983 Pfam PF09397 Ftsk gamma domain 823 880 1.4E-21 T 14-10-2018 IPR018541 FtsK gamma domain MB46_03885 83968eabeb5d00c3801ef99ccec0b502 983 Gene3D G3DSA:3.40.50.300 517 806 8.5E-103 T 14-10-2018 MB46_03885 83968eabeb5d00c3801ef99ccec0b502 983 Gene3D G3DSA:3.30.980.40 414 516 2.0E-28 T 14-10-2018 MB46_03885 83968eabeb5d00c3801ef99ccec0b502 983 SUPERFAMILY SSF46785 819 884 5.3E-17 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_03885 83968eabeb5d00c3801ef99ccec0b502 983 SMART SM00382 555 753 0.0052 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_03885 83968eabeb5d00c3801ef99ccec0b502 983 SUPERFAMILY SSF52540 494 793 4.3E-46 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_03885 83968eabeb5d00c3801ef99ccec0b502 983 Gene3D G3DSA:1.10.10.10 823 884 1.4E-18 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_03885 83968eabeb5d00c3801ef99ccec0b502 983 Pfam PF01580 FtsK/SpoIIIE family 521 720 1.9E-56 T 14-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 MB46_03885 83968eabeb5d00c3801ef99ccec0b502 983 SMART SM00843 818 883 5.5E-29 T 14-10-2018 IPR018541 FtsK gamma domain MB46_09055 d348d6e62506ee1bdaa93443f9a7f376 198 Pfam PF00574 Clp protease 12 184 2.6E-75 T 14-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA MB46_09055 d348d6e62506ee1bdaa93443f9a7f376 198 PRINTS PR00127 Clp protease catalytic subunit P signature 12 27 1.5E-45 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MB46_09055 d348d6e62506ee1bdaa93443f9a7f376 198 PRINTS PR00127 Clp protease catalytic subunit P signature 52 72 1.5E-45 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MB46_09055 d348d6e62506ee1bdaa93443f9a7f376 198 PRINTS PR00127 Clp protease catalytic subunit P signature 83 100 1.5E-45 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MB46_09055 d348d6e62506ee1bdaa93443f9a7f376 198 PRINTS PR00127 Clp protease catalytic subunit P signature 161 180 1.5E-45 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MB46_09055 d348d6e62506ee1bdaa93443f9a7f376 198 PRINTS PR00127 Clp protease catalytic subunit P signature 104 123 1.5E-45 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MB46_09055 d348d6e62506ee1bdaa93443f9a7f376 198 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 105 118 - T 14-10-2018 IPR033135 ClpP, histidine active site MB46_09055 d348d6e62506ee1bdaa93443f9a7f376 198 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 1 186 37.686 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MB46_09055 d348d6e62506ee1bdaa93443f9a7f376 198 Gene3D G3DSA:3.90.226.10 2 187 1.4E-71 T 14-10-2018 MB46_09055 d348d6e62506ee1bdaa93443f9a7f376 198 SUPERFAMILY SSF52096 12 185 5.25E-65 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MB46_15620 fcf1e2e076a9c6b2fb5ad17f4de9a667 103 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 14 29 9.3E-8 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MB46_15620 fcf1e2e076a9c6b2fb5ad17f4de9a667 103 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 46 61 9.3E-8 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MB46_15620 fcf1e2e076a9c6b2fb5ad17f4de9a667 103 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 61 76 9.3E-8 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MB46_15620 fcf1e2e076a9c6b2fb5ad17f4de9a667 103 SMART SM00418 12 90 2.8E-23 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MB46_15620 fcf1e2e076a9c6b2fb5ad17f4de9a667 103 SUPERFAMILY SSF46785 7 90 4.17E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_15620 fcf1e2e076a9c6b2fb5ad17f4de9a667 103 Pfam PF01022 Bacterial regulatory protein, arsR family 19 62 2.0E-13 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MB46_15620 fcf1e2e076a9c6b2fb5ad17f4de9a667 103 Gene3D G3DSA:1.10.10.10 4 95 2.0E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_13585 b7620ff14750d59c02f36c5f2aa631e8 365 SUPERFAMILY SSF101790 271 342 5.63E-8 T 14-10-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal MB46_13585 b7620ff14750d59c02f36c5f2aa631e8 365 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 252 341 1.9E-10 T 14-10-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 MB46_13585 b7620ff14750d59c02f36c5f2aa631e8 365 PIRSF PIRSF006487 38 149 6.2E-10 T 14-10-2018 IPR028896 Aminomethyltransferase-like KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 MB46_13585 b7620ff14750d59c02f36c5f2aa631e8 365 PIRSF PIRSF006487 198 345 3.2E-5 T 14-10-2018 IPR028896 Aminomethyltransferase-like KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 MB46_13585 b7620ff14750d59c02f36c5f2aa631e8 365 SUPERFAMILY SSF103025 24 267 2.67E-51 T 14-10-2018 MB46_13585 b7620ff14750d59c02f36c5f2aa631e8 365 Pfam PF01571 Aminomethyltransferase folate-binding domain 46 146 5.5E-15 T 14-10-2018 IPR006222 Aminomethyltransferase, folate-binding domain MB46_13585 b7620ff14750d59c02f36c5f2aa631e8 365 TIGRFAM TIGR03317 ygfZ_signature: folate-binding protein YgfZ 216 277 9.0E-19 T 14-10-2018 IPR017703 YgfZ/GcvT conserved site MB46_13585 b7620ff14750d59c02f36c5f2aa631e8 365 Gene3D G3DSA:3.30.1360.120 29 342 3.1E-59 T 14-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 MB46_13050 507ae43903437014ae8e6b24fab93167 291 SMART SM00382 30 211 7.1E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_13050 507ae43903437014ae8e6b24fab93167 291 Gene3D G3DSA:3.40.50.300 2 222 2.2E-57 T 14-10-2018 MB46_13050 507ae43903437014ae8e6b24fab93167 291 SUPERFAMILY SSF52540 6 216 1.07E-55 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_13050 507ae43903437014ae8e6b24fab93167 291 ProSitePatterns PS00211 ABC transporters family signature. 132 146 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_13050 507ae43903437014ae8e6b24fab93167 291 Pfam PF00005 ABC transporter 22 159 1.1E-26 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_07710 dd01303e05b2bc57faf1e54d99ed91ce 246 Pfam PF04973 Nicotinamide mononucleotide transporter 22 216 2.4E-51 T 14-10-2018 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 MB46_07710 dd01303e05b2bc57faf1e54d99ed91ce 246 TIGRFAM TIGR01528 NMN_trans_PnuC: nicotinamide mononucleotide transporter PnuC 22 216 5.2E-16 T 14-10-2018 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 MB46_04530 8c50ff569c2aa86f2199e9ee873db9a0 277 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 128 145 - T 14-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 MB46_04530 8c50ff569c2aa86f2199e9ee873db9a0 277 Pfam PF00248 Aldo/keto reductase family 24 264 2.4E-45 T 14-10-2018 IPR023210 NADP-dependent oxidoreductase domain MB46_04530 8c50ff569c2aa86f2199e9ee873db9a0 277 SUPERFAMILY SSF51430 7 268 7.86E-90 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily MB46_04530 8c50ff569c2aa86f2199e9ee873db9a0 277 Gene3D G3DSA:3.20.20.100 2 277 5.4E-106 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily MB46_04530 8c50ff569c2aa86f2199e9ee873db9a0 277 PRINTS PR00069 Aldo-keto reductase signature 96 114 4.1E-45 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MB46_04530 8c50ff569c2aa86f2199e9ee873db9a0 277 PRINTS PR00069 Aldo-keto reductase signature 37 61 4.1E-45 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MB46_04530 8c50ff569c2aa86f2199e9ee873db9a0 277 PRINTS PR00069 Aldo-keto reductase signature 128 145 4.1E-45 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MB46_04530 8c50ff569c2aa86f2199e9ee873db9a0 277 PRINTS PR00069 Aldo-keto reductase signature 162 191 4.1E-45 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MB46_04530 8c50ff569c2aa86f2199e9ee873db9a0 277 PRINTS PR00069 Aldo-keto reductase signature 199 223 4.1E-45 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MB46_04530 8c50ff569c2aa86f2199e9ee873db9a0 277 PIRSF PIRSF000097 2 276 5.9E-80 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MB46_12855 4f64eca0df24137f4c88462b8b06463d 303 Hamap MF_01876 Pseudouridine-5'-phosphate glycosidase [psuG]. 10 303 38.03 T 14-10-2018 IPR007342 Pseudouridine-5'-phosphate glycosidase GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 MB46_12855 4f64eca0df24137f4c88462b8b06463d 303 Gene3D G3DSA:3.40.1790.10 2 303 2.3E-112 T 14-10-2018 IPR022830 Indigoidine synthase A-like GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 MB46_12855 4f64eca0df24137f4c88462b8b06463d 303 Pfam PF04227 Indigoidine synthase A like protein 11 299 3.5E-111 T 14-10-2018 IPR007342 Pseudouridine-5'-phosphate glycosidase GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 MB46_12855 4f64eca0df24137f4c88462b8b06463d 303 SUPERFAMILY SSF110581 5 302 1.83E-98 T 14-10-2018 IPR022830 Indigoidine synthase A-like GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 MB46_09875 8e8643c5d4227cba7c05721155bc7e9a 352 SUPERFAMILY SSF53807 57 346 7.06E-46 T 14-10-2018 MB46_09875 8e8643c5d4227cba7c05721155bc7e9a 352 Gene3D G3DSA:3.40.50.1980 59 160 3.2E-17 T 14-10-2018 MB46_09875 8e8643c5d4227cba7c05721155bc7e9a 352 Gene3D G3DSA:3.40.50.1980 165 351 1.0E-32 T 14-10-2018 MB46_09875 8e8643c5d4227cba7c05721155bc7e9a 352 Pfam PF01497 Periplasmic binding protein 75 326 1.1E-18 T 14-10-2018 IPR002491 ABC transporter periplasmic binding domain MB46_04245 b93d5e3771cd7c0e7269c45b9af7f270 336 PIRSF PIRSF000915 1 267 9.4E-63 T 14-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA MB46_04245 b93d5e3771cd7c0e7269c45b9af7f270 336 Gene3D G3DSA:3.40.50.1000 11 239 5.1E-79 T 14-10-2018 IPR023214 HAD superfamily MB46_04245 b93d5e3771cd7c0e7269c45b9af7f270 336 Pfam PF13242 HAD-hyrolase-like 189 261 8.7E-17 T 14-10-2018 MB46_04245 b93d5e3771cd7c0e7269c45b9af7f270 336 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 13 236 1.6E-38 T 14-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA MB46_04245 b93d5e3771cd7c0e7269c45b9af7f270 336 Gene3D G3DSA:3.40.50.1000 78 189 5.1E-79 T 14-10-2018 IPR023214 HAD superfamily MB46_04245 b93d5e3771cd7c0e7269c45b9af7f270 336 Pfam PF13344 Haloacid dehalogenase-like hydrolase 13 114 1.0E-24 T 14-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA MB46_04245 b93d5e3771cd7c0e7269c45b9af7f270 336 SUPERFAMILY SSF56784 9 263 5.76E-60 T 14-10-2018 IPR036412 HAD-like superfamily MB46_05050 f431170f84f55cbeeff41deb3301b248 326 Pfam PF02650 WhiA C-terminal HTH domain 221 303 8.7E-19 T 14-10-2018 IPR023054 Sporulation regulator WhiA, C-terminal MB46_05050 f431170f84f55cbeeff41deb3301b248 326 TIGRFAM TIGR00647 DNA_bind_WhiA: DNA-binding protein WhiA 4 304 3.7E-103 T 14-10-2018 IPR033981 Sporulation regulator WhiA-like MB46_05050 f431170f84f55cbeeff41deb3301b248 326 Hamap MF_01420 Putative sporulation transcription regulator WhiA [whiA]. 3 306 29.735 T 14-10-2018 IPR003802 Sporulation regulator WhiA GO:0043937 MB46_05050 f431170f84f55cbeeff41deb3301b248 326 Pfam PF14527 WhiA LAGLIDADG-like domain 127 218 1.5E-22 T 14-10-2018 IPR039518 WhiA, LAGLIDADG-like domain MB46_05050 f431170f84f55cbeeff41deb3301b248 326 Gene3D G3DSA:1.10.10.10 216 307 3.5E-15 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_05050 f431170f84f55cbeeff41deb3301b248 326 Pfam PF10298 WhiA N-terminal LAGLIDADG-like domain 20 104 2.4E-25 T 14-10-2018 IPR018478 Sporulation transcription regulator WhiA, N-terminal domain MB46_05050 f431170f84f55cbeeff41deb3301b248 326 Gene3D G3DSA:3.10.28.10 2 213 3.4E-19 T 14-10-2018 IPR027434 Homing endonuclease MB46_01920 3e372c8f93b356f56abe92ce2b8e8123 599 Pfam PF02910 Fumarate reductase flavoprotein C-term 463 599 2.4E-40 T 14-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MB46_01920 3e372c8f93b356f56abe92ce2b8e8123 599 TIGRFAM TIGR01816 sdhA_forward: succinate dehydrogenase, flavoprotein subunit 4 599 1.3E-275 T 14-10-2018 IPR011281 Succinate dehydrogenase, flavoprotein subunit GO:0006099|GO:0016627|GO:0050660|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 MB46_01920 3e372c8f93b356f56abe92ce2b8e8123 599 SUPERFAMILY SSF56425 245 363 3.29E-41 T 14-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 MB46_01920 3e372c8f93b356f56abe92ce2b8e8123 599 TIGRFAM TIGR01812 sdhA_frdA_Gneg: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 7 599 1.2E-240 T 14-10-2018 IPR014006 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit GO:0016627|GO:0022900|GO:0050660|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MB46_01920 3e372c8f93b356f56abe92ce2b8e8123 599 Pfam PF00890 FAD binding domain 7 409 9.2E-112 T 14-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 MB46_01920 3e372c8f93b356f56abe92ce2b8e8123 599 SUPERFAMILY SSF51905 2 446 2.68E-71 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_01920 3e372c8f93b356f56abe92ce2b8e8123 599 SUPERFAMILY SSF46977 454 599 7.19E-44 T 14-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MB46_01920 3e372c8f93b356f56abe92ce2b8e8123 599 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 372 394 2.2E-6 T 14-10-2018 MB46_01920 3e372c8f93b356f56abe92ce2b8e8123 599 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 2.2E-6 T 14-10-2018 MB46_01920 3e372c8f93b356f56abe92ce2b8e8123 599 Gene3D G3DSA:1.20.58.100 437 550 1.2E-32 T 14-10-2018 MB46_01920 3e372c8f93b356f56abe92ce2b8e8123 599 Gene3D G3DSA:3.50.50.60 7 420 1.8E-158 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_01920 3e372c8f93b356f56abe92ce2b8e8123 599 PIRSF PIRSF000171 1 584 7.6E-48 T 14-10-2018 MB46_01920 3e372c8f93b356f56abe92ce2b8e8123 599 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 40 49 - T 14-10-2018 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MB46_01920 3e372c8f93b356f56abe92ce2b8e8123 599 Gene3D G3DSA:3.90.700.10 255 358 1.8E-158 T 14-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 MB46_17115 95cd159374237047821dba8bf4ba442e 301 SUPERFAMILY SSF161098 32 301 5.23E-61 T 14-10-2018 IPR035906 MetI-like superfamily MB46_17115 95cd159374237047821dba8bf4ba442e 301 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 127 294 2.1E-11 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_17115 95cd159374237047821dba8bf4ba442e 301 Gene3D G3DSA:1.10.3720.10 34 292 6.7E-57 T 14-10-2018 IPR035906 MetI-like superfamily MB46_03250 0755b9a3b356c7928980ed5882c75409 386 Gene3D G3DSA:3.30.70.2450 185 264 6.1E-72 T 14-10-2018 MB46_03250 0755b9a3b356c7928980ed5882c75409 386 Pfam PF01494 FAD binding domain 3 339 8.7E-45 T 14-10-2018 IPR002938 FAD-binding domain GO:0071949 MB46_03250 0755b9a3b356c7928980ed5882c75409 386 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 290 306 8.8E-25 T 14-10-2018 MB46_03250 0755b9a3b356c7928980ed5882c75409 386 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 275 290 8.8E-25 T 14-10-2018 MB46_03250 0755b9a3b356c7928980ed5882c75409 386 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 8.8E-25 T 14-10-2018 MB46_03250 0755b9a3b356c7928980ed5882c75409 386 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 156 171 8.8E-25 T 14-10-2018 MB46_03250 0755b9a3b356c7928980ed5882c75409 386 Gene3D G3DSA:3.50.50.60 4 337 6.1E-72 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_03250 0755b9a3b356c7928980ed5882c75409 386 SUPERFAMILY SSF51905 1 369 4.07E-50 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_01695 9efbe4c43f0f8029e49032295d92e826 167 Pfam PF00210 Ferritin-like domain 9 144 1.1E-30 T 14-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 MB46_01695 9efbe4c43f0f8029e49032295d92e826 167 Gene3D G3DSA:1.20.1260.10 2 167 1.4E-40 T 14-10-2018 IPR012347 Ferritin-like MB46_01695 9efbe4c43f0f8029e49032295d92e826 167 SUPERFAMILY SSF47240 4 161 1.03E-46 T 14-10-2018 IPR009078 Ferritin-like superfamily MB46_05855 d7f25675def06c7367597bffff85fffe 124 Hamap MF_01954 Urease subunit beta [ureB]. 1 101 31.32 T 14-10-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MB46_05855 d7f25675def06c7367597bffff85fffe 124 Pfam PF00699 Urease beta subunit 3 99 2.0E-43 T 14-10-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MB46_05855 d7f25675def06c7367597bffff85fffe 124 Gene3D G3DSA:2.10.150.10 1 122 6.4E-47 T 14-10-2018 IPR036461 Urease, beta subunit superfamily KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MB46_05855 d7f25675def06c7367597bffff85fffe 124 TIGRFAM TIGR00192 urease_beta: urease, beta subunit 1 102 8.8E-45 T 14-10-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MB46_05855 d7f25675def06c7367597bffff85fffe 124 SUPERFAMILY SSF51278 1 107 3.4E-47 T 14-10-2018 IPR036461 Urease, beta subunit superfamily KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MB46_10115 438c40f007575cb042474384d25b7709 278 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 90 267 7.9E-18 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_10115 438c40f007575cb042474384d25b7709 278 Gene3D G3DSA:1.10.3720.10 1 265 3.3E-66 T 14-10-2018 IPR035906 MetI-like superfamily MB46_10115 438c40f007575cb042474384d25b7709 278 SUPERFAMILY SSF161098 9 278 8.6E-77 T 14-10-2018 IPR035906 MetI-like superfamily MB46_09355 027bec0a7b37d17e2cfd4174fa0020ac 534 Pfam PF00009 Elongation factor Tu GTP binding domain 20 282 1.7E-47 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MB46_09355 027bec0a7b37d17e2cfd4174fa0020ac 534 TIGRFAM TIGR00503 prfC: peptide chain release factor 3 18 530 4.5E-160 T 14-10-2018 IPR004548 Peptide chain release factor 3 GO:0003924|GO:0005737|GO:0006415 MB46_09355 027bec0a7b37d17e2cfd4174fa0020ac 534 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 66 81 - T 14-10-2018 IPR031157 Tr-type G domain, conserved site MB46_09355 027bec0a7b37d17e2cfd4174fa0020ac 534 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 25 158 1.3E-21 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MB46_09355 027bec0a7b37d17e2cfd4174fa0020ac 534 Pfam PF16658 Class II release factor RF3, C-terminal domain 392 518 3.9E-38 T 14-10-2018 IPR032090 Peptide chain release factor 3, C-terminal MB46_09355 027bec0a7b37d17e2cfd4174fa0020ac 534 Gene3D G3DSA:3.40.50.300 80 384 8.4E-92 T 14-10-2018 MB46_09355 027bec0a7b37d17e2cfd4174fa0020ac 534 SUPERFAMILY SSF52540 18 282 1.31E-76 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_09355 027bec0a7b37d17e2cfd4174fa0020ac 534 Gene3D G3DSA:3.40.50.300 118 280 8.4E-92 T 14-10-2018 MB46_09355 027bec0a7b37d17e2cfd4174fa0020ac 534 Hamap MF_00072 Peptide chain release factor 3 [prfC]. 12 531 46.192 T 14-10-2018 IPR004548 Peptide chain release factor 3 GO:0003924|GO:0005737|GO:0006415 MB46_09355 027bec0a7b37d17e2cfd4174fa0020ac 534 SUPERFAMILY SSF50447 267 393 4.48E-23 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily MB46_09355 027bec0a7b37d17e2cfd4174fa0020ac 534 PRINTS PR00315 GTP-binding elongation factor signature 109 120 2.6E-11 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MB46_09355 027bec0a7b37d17e2cfd4174fa0020ac 534 PRINTS PR00315 GTP-binding elongation factor signature 145 154 2.6E-11 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MB46_09355 027bec0a7b37d17e2cfd4174fa0020ac 534 PRINTS PR00315 GTP-binding elongation factor signature 23 36 2.6E-11 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MB46_09355 027bec0a7b37d17e2cfd4174fa0020ac 534 PRINTS PR00315 GTP-binding elongation factor signature 73 81 2.6E-11 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MB46_09355 027bec0a7b37d17e2cfd4174fa0020ac 534 PRINTS PR00315 GTP-binding elongation factor signature 93 103 2.6E-11 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MB46_09355 027bec0a7b37d17e2cfd4174fa0020ac 534 SUPERFAMILY SSF54980 398 471 2.09E-10 T 14-10-2018 IPR035647 EF-G domain III/V-like MB46_09355 027bec0a7b37d17e2cfd4174fa0020ac 534 Gene3D G3DSA:3.30.70.3280 395 532 3.9E-41 T 14-10-2018 IPR038467 Peptide chain release factor 3, C-terminal domain superfamily MB46_15055 c26b788781102857431adf94cf71908b 343 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 135 326 2.7E-21 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_15055 c26b788781102857431adf94cf71908b 343 Gene3D G3DSA:1.10.3720.10 29 324 5.4E-63 T 14-10-2018 IPR035906 MetI-like superfamily MB46_15055 c26b788781102857431adf94cf71908b 343 SUPERFAMILY SSF161098 35 329 2.15E-56 T 14-10-2018 IPR035906 MetI-like superfamily MB46_12430 978683e84527762864a35f369b4a701d 252 SMART SM00382 35 222 1.4E-17 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_12430 978683e84527762864a35f369b4a701d 252 Gene3D G3DSA:3.40.50.300 8 251 5.9E-80 T 14-10-2018 MB46_12430 978683e84527762864a35f369b4a701d 252 SUPERFAMILY SSF52540 10 244 7.86E-81 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_12430 978683e84527762864a35f369b4a701d 252 PIRSF PIRSF039085 7 250 7.9E-111 T 14-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 MB46_12430 978683e84527762864a35f369b4a701d 252 Pfam PF00005 ABC transporter 26 174 2.0E-35 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_12430 978683e84527762864a35f369b4a701d 252 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_03600 f3552f8f9df827b386e0c20f0c817277 389 PIRSF PIRSF016578 2 388 1.1E-16 T 14-10-2018 MB46_03600 f3552f8f9df827b386e0c20f0c817277 389 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 125 227 4.4E-19 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MB46_03600 f3552f8f9df827b386e0c20f0c817277 389 SUPERFAMILY SSF56645 4 252 1.31E-71 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 MB46_03600 f3552f8f9df827b386e0c20f0c817277 389 Gene3D G3DSA:1.20.140.10 246 389 5.7E-46 T 14-10-2018 MB46_03600 f3552f8f9df827b386e0c20f0c817277 389 Gene3D G3DSA:1.10.540.10 2 123 1.2E-40 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 MB46_03600 f3552f8f9df827b386e0c20f0c817277 389 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 127 139 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 MB46_03600 f3552f8f9df827b386e0c20f0c817277 389 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 9 121 3.3E-34 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MB46_03600 f3552f8f9df827b386e0c20f0c817277 389 SUPERFAMILY SSF47203 239 387 1.29E-45 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 MB46_03600 f3552f8f9df827b386e0c20f0c817277 389 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 239 387 1.8E-44 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MB46_03600 f3552f8f9df827b386e0c20f0c817277 389 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 346 365 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 MB46_03600 f3552f8f9df827b386e0c20f0c817277 389 Gene3D G3DSA:2.40.110.10 125 245 4.6E-31 T 14-10-2018 MB46_12180 c21ca58cd971eb430ac18b8d1533b454 367 Gene3D G3DSA:3.50.50.60 1 363 1.5E-97 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_12180 c21ca58cd971eb430ac18b8d1533b454 367 SUPERFAMILY SSF51905 3 224 1.02E-37 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_12180 c21ca58cd971eb430ac18b8d1533b454 367 SUPERFAMILY SSF51905 181 361 7.51E-9 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_12180 c21ca58cd971eb430ac18b8d1533b454 367 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 182 200 3.1E-11 T 14-10-2018 MB46_12180 c21ca58cd971eb430ac18b8d1533b454 367 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 291 307 3.1E-11 T 14-10-2018 MB46_12180 c21ca58cd971eb430ac18b8d1533b454 367 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 3.1E-11 T 14-10-2018 MB46_12180 c21ca58cd971eb430ac18b8d1533b454 367 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 322 1.3E-16 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MB46_12180 c21ca58cd971eb430ac18b8d1533b454 367 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 6.5E-11 T 14-10-2018 MB46_12180 c21ca58cd971eb430ac18b8d1533b454 367 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 141 150 6.5E-11 T 14-10-2018 MB46_12180 c21ca58cd971eb430ac18b8d1533b454 367 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 182 207 6.5E-11 T 14-10-2018 MB46_13865 b4bc3ab028cccdc0e5c8a2ae92d20b31 249 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 147 175 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MB46_13865 b4bc3ab028cccdc0e5c8a2ae92d20b31 249 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 248 1.9E-38 T 14-10-2018 MB46_13865 b4bc3ab028cccdc0e5c8a2ae92d20b31 249 SUPERFAMILY SSF51735 4 248 1.53E-55 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_13865 b4bc3ab028cccdc0e5c8a2ae92d20b31 249 Gene3D G3DSA:3.40.50.720 1 249 3.4E-56 T 14-10-2018 MB46_13865 b4bc3ab028cccdc0e5c8a2ae92d20b31 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 9.4E-19 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_13865 b4bc3ab028cccdc0e5c8a2ae92d20b31 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 9.4E-19 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_13865 b4bc3ab028cccdc0e5c8a2ae92d20b31 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 9.4E-19 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_13865 b4bc3ab028cccdc0e5c8a2ae92d20b31 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 9.4E-19 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_16920 8af693b06f94bdb0d693bf3f2f992824 161 Pfam PF02080 TrkA-C domain 89 156 1.6E-15 T 14-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 MB46_16920 8af693b06f94bdb0d693bf3f2f992824 161 PIRSF PIRSF005028 1 161 2.7E-55 T 14-10-2018 IPR026278 Potassium/proton antiporter subunit KhtT MB46_16920 8af693b06f94bdb0d693bf3f2f992824 161 Gene3D G3DSA:3.30.70.1450 88 158 3.2E-16 T 14-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 MB46_16920 8af693b06f94bdb0d693bf3f2f992824 161 SUPERFAMILY SSF116726 84 154 1.31E-16 T 14-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 MB46_03355 6e9761a7bdc54355c51f3c50f398005c 409 Pfam PF07690 Major Facilitator Superfamily 28 369 1.8E-40 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MB46_03355 6e9761a7bdc54355c51f3c50f398005c 409 Gene3D G3DSA:1.20.1720.10 22 400 4.0E-94 T 14-10-2018 MB46_03355 6e9761a7bdc54355c51f3c50f398005c 409 SUPERFAMILY SSF103473 12 407 5.23E-62 T 14-10-2018 IPR036259 MFS transporter superfamily MB46_03355 6e9761a7bdc54355c51f3c50f398005c 409 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 19 399 5.4E-81 T 14-10-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0006855|GO:0015238|GO:0016021 MB46_03355 6e9761a7bdc54355c51f3c50f398005c 409 ProSitePatterns PS00216 Sugar transport proteins signature 1. 76 93 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MB46_15540 05d9ad8c90ce6fdf0384c4ca60998d7e 533 Pfam PF14262 Carbohydrate-binding domain-containing protein Cthe_2159 98 338 1.5E-70 T 14-10-2018 IPR025584 Carbohydrate-binding domain-containing protein Cthe_2159 MB46_02865 71b8236cb72555e1024295c84fccb96f 161 Gene3D G3DSA:3.40.140.10 7 161 1.5E-48 T 14-10-2018 MB46_02865 71b8236cb72555e1024295c84fccb96f 161 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 9 104 3.6E-19 T 14-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain MB46_02865 71b8236cb72555e1024295c84fccb96f 161 SUPERFAMILY SSF53927 6 128 6.36E-37 T 14-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 MB46_17035 69f87da7e2721035e10a35197e0584aa 307 Gene3D G3DSA:3.20.10.10 133 306 2.4E-52 T 14-10-2018 MB46_17035 69f87da7e2721035e10a35197e0584aa 307 SUPERFAMILY SSF56752 14 289 2.35E-52 T 14-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 MB46_17035 69f87da7e2721035e10a35197e0584aa 307 Gene3D G3DSA:3.30.470.10 1 129 7.5E-33 T 14-10-2018 MB46_17035 69f87da7e2721035e10a35197e0584aa 307 Pfam PF01063 Amino-transferase class IV 36 281 7.1E-43 T 14-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 MB46_15395 22d6c233d912eaea6434c13d29140c87 164 Gene3D G3DSA:3.40.630.30 2 134 5.1E-28 T 14-10-2018 MB46_15395 22d6c233d912eaea6434c13d29140c87 164 SUPERFAMILY SSF55729 3 121 8.06E-21 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase MB46_15395 22d6c233d912eaea6434c13d29140c87 164 Pfam PF00583 Acetyltransferase (GNAT) family 41 105 2.9E-10 T 14-10-2018 IPR000182 GNAT domain MB46_13970 f57bd0eea8ae93a85622018105669930 371 Gene3D G3DSA:3.40.50.720 180 317 8.5E-90 T 14-10-2018 MB46_13970 f57bd0eea8ae93a85622018105669930 371 Pfam PF00107 Zinc-binding dehydrogenase 203 330 1.7E-22 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 MB46_13970 f57bd0eea8ae93a85622018105669930 371 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 42 158 2.7E-24 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MB46_13970 f57bd0eea8ae93a85622018105669930 371 SUPERFAMILY SSF51735 169 335 6.68E-37 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_13970 f57bd0eea8ae93a85622018105669930 371 Gene3D G3DSA:3.90.180.10 26 356 8.5E-90 T 14-10-2018 MB46_13970 f57bd0eea8ae93a85622018105669930 371 SUPERFAMILY SSF50129 14 202 9.43E-44 T 14-10-2018 IPR011032 GroES-like superfamily MB46_13805 9ffdddbd7746c04be729acb8a8b1ab05 2011 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 915 952 7.4E-4 T 14-10-2018 IPR001434 Domain of unknown function DUF11 MB46_13805 9ffdddbd7746c04be729acb8a8b1ab05 2011 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 554 589 1.2E-5 T 14-10-2018 IPR001434 Domain of unknown function DUF11 MB46_13805 9ffdddbd7746c04be729acb8a8b1ab05 2011 Gene3D G3DSA:2.60.40.1140 1759 1867 9.3E-6 T 14-10-2018 MB46_13805 9ffdddbd7746c04be729acb8a8b1ab05 2011 Gene3D G3DSA:2.60.40.1140 1868 1966 2.4E-6 T 14-10-2018 MB46_17675 fcdca008cd9a0f126e92bd7d4fd7bb71 250 Gene3D G3DSA:3.40.50.1820 9 248 4.6E-56 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_17675 fcdca008cd9a0f126e92bd7d4fd7bb71 250 Pfam PF07859 alpha/beta hydrolase fold 26 215 2.3E-13 T 14-10-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0016787 MB46_17675 fcdca008cd9a0f126e92bd7d4fd7bb71 250 SUPERFAMILY SSF53474 11 244 1.03E-35 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_14100 c39c5651a1144096f235cb0f2989ed77 502 Gene3D G3DSA:1.20.1740.10 23 494 8.4E-113 T 14-10-2018 MB46_14100 c39c5651a1144096f235cb0f2989ed77 502 Pfam PF13520 Amino acid permease 27 456 1.1E-55 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 MB46_14100 c39c5651a1144096f235cb0f2989ed77 502 PIRSF PIRSF006060 7 499 7.3E-89 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 MB46_17715 ce147dbd540defb19079010f9199c326 313 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 122 301 7.1E-22 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_17715 ce147dbd540defb19079010f9199c326 313 SUPERFAMILY SSF161098 39 313 1.44E-71 T 14-10-2018 IPR035906 MetI-like superfamily MB46_17715 ce147dbd540defb19079010f9199c326 313 Gene3D G3DSA:1.10.3720.10 34 301 2.5E-65 T 14-10-2018 IPR035906 MetI-like superfamily MB46_17875 becb575f28a8112b49c4a849c4a1f07f 432 Gene3D G3DSA:3.30.110.90 57 350 3.1E-59 T 14-10-2018 MB46_17875 becb575f28a8112b49c4a849c4a1f07f 432 SUPERFAMILY SSF51338 5 380 5.04E-12 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 MB46_17875 becb575f28a8112b49c4a849c4a1f07f 432 SUPERFAMILY SSF51556 56 349 1.11E-50 T 14-10-2018 IPR032466 Metal-dependent hydrolase MB46_17875 becb575f28a8112b49c4a849c4a1f07f 432 Pfam PF01979 Amidohydrolase family 53 372 3.3E-20 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 MB46_17875 becb575f28a8112b49c4a849c4a1f07f 432 Gene3D G3DSA:1.20.58.520 232 328 3.1E-59 T 14-10-2018 MB46_17875 becb575f28a8112b49c4a849c4a1f07f 432 Gene3D G3DSA:3.40.50.10910 112 231 3.1E-59 T 14-10-2018 MB46_17875 becb575f28a8112b49c4a849c4a1f07f 432 Gene3D G3DSA:2.30.40.10 9 384 3.1E-59 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 MB46_10955 1afcd2a8603142d1cbb19744276b68aa 550 SUPERFAMILY SSF52374 121 438 1.01E-81 T 14-10-2018 MB46_10955 1afcd2a8603142d1cbb19744276b68aa 550 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 30 550 1.6E-121 T 14-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 MB46_10955 1afcd2a8603142d1cbb19744276b68aa 550 Gene3D G3DSA:3.40.50.620 124 423 2.5E-144 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MB46_10955 1afcd2a8603142d1cbb19744276b68aa 550 Gene3D G3DSA:3.30.1360.70 4 113 2.5E-21 T 14-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 MB46_10955 1afcd2a8603142d1cbb19744276b68aa 550 Gene3D G3DSA:1.10.730.10 424 550 2.5E-144 T 14-10-2018 MB46_10955 1afcd2a8603142d1cbb19744276b68aa 550 Pfam PF05746 DALR anticodon binding domain 429 550 3.2E-30 T 14-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 MB46_10955 1afcd2a8603142d1cbb19744276b68aa 550 SUPERFAMILY SSF47323 423 550 4.64E-31 T 14-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 MB46_10955 1afcd2a8603142d1cbb19744276b68aa 550 Pfam PF00750 tRNA synthetases class I (R) 117 390 2.0E-17 T 14-10-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 MB46_10955 1afcd2a8603142d1cbb19744276b68aa 550 Hamap MF_00123 Arginine--tRNA ligase [argS]. 8 550 24.995 T 14-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 MB46_10955 1afcd2a8603142d1cbb19744276b68aa 550 SMART SM01016 4 95 8.5E-33 T 14-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 MB46_10955 1afcd2a8603142d1cbb19744276b68aa 550 PRINTS PR01038 Arginyl-tRNA synthetase signature 124 139 4.5E-24 T 14-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 MB46_10955 1afcd2a8603142d1cbb19744276b68aa 550 PRINTS PR01038 Arginyl-tRNA synthetase signature 298 319 4.5E-24 T 14-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 MB46_10955 1afcd2a8603142d1cbb19744276b68aa 550 PRINTS PR01038 Arginyl-tRNA synthetase signature 163 176 4.5E-24 T 14-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 MB46_10955 1afcd2a8603142d1cbb19744276b68aa 550 PRINTS PR01038 Arginyl-tRNA synthetase signature 139 155 4.5E-24 T 14-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 MB46_10955 1afcd2a8603142d1cbb19744276b68aa 550 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 6 94 1.3E-20 T 14-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 MB46_10955 1afcd2a8603142d1cbb19744276b68aa 550 SUPERFAMILY SSF55190 25 105 1.29E-18 T 14-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 MB46_10955 1afcd2a8603142d1cbb19744276b68aa 550 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 134 143 - T 14-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 MB46_10955 1afcd2a8603142d1cbb19744276b68aa 550 SMART SM00836 429 550 1.6E-39 T 14-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 MB46_11530 f5d8322dfc73bab3a7e77a888bff7d14 429 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2 182 2.3E-32 T 14-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 MB46_11530 f5d8322dfc73bab3a7e77a888bff7d14 429 SUPERFAMILY SSF52413 311 418 4.32E-11 T 14-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 MB46_11530 f5d8322dfc73bab3a7e77a888bff7d14 429 PIRSF PIRSF000124 1 427 2.6E-48 T 14-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 MB46_11530 f5d8322dfc73bab3a7e77a888bff7d14 429 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 2 410 4.7E-87 T 14-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 MB46_11530 f5d8322dfc73bab3a7e77a888bff7d14 429 Gene3D G3DSA:3.40.50.720 1 198 5.3E-58 T 14-10-2018 MB46_11530 f5d8322dfc73bab3a7e77a888bff7d14 429 SUPERFAMILY SSF48179 214 304 3.74E-20 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MB46_11530 f5d8322dfc73bab3a7e77a888bff7d14 429 SUPERFAMILY SSF51735 2 192 3.43E-41 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_11530 f5d8322dfc73bab3a7e77a888bff7d14 429 PIRSF PIRSF500136 1 428 3.8E-97 T 14-10-2018 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 MB46_11530 f5d8322dfc73bab3a7e77a888bff7d14 429 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 214 298 2.3E-17 T 14-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 MB46_11530 f5d8322dfc73bab3a7e77a888bff7d14 429 Gene3D G3DSA:3.40.50.720 212 429 4.7E-43 T 14-10-2018 MB46_11530 f5d8322dfc73bab3a7e77a888bff7d14 429 SMART SM00984 322 415 7.5E-6 T 14-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 MB46_00255 12297e3b75b9756f7884a9555b4b8eaa 404 SMART SM00633 72 350 2.2E-7 T 14-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 MB46_00255 12297e3b75b9756f7884a9555b4b8eaa 404 PRINTS PR00134 Glycosyl hydrolase family 10 signature 101 113 5.4E-8 T 14-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 MB46_00255 12297e3b75b9756f7884a9555b4b8eaa 404 PRINTS PR00134 Glycosyl hydrolase family 10 signature 143 154 5.4E-8 T 14-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 MB46_00255 12297e3b75b9756f7884a9555b4b8eaa 404 PRINTS PR00134 Glycosyl hydrolase family 10 signature 196 207 5.4E-8 T 14-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 MB46_00255 12297e3b75b9756f7884a9555b4b8eaa 404 PRINTS PR00134 Glycosyl hydrolase family 10 signature 219 231 5.4E-8 T 14-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 MB46_00255 12297e3b75b9756f7884a9555b4b8eaa 404 SUPERFAMILY SSF51445 23 355 7.58E-63 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily MB46_00255 12297e3b75b9756f7884a9555b4b8eaa 404 Gene3D G3DSA:3.20.20.80 30 352 6.7E-55 T 14-10-2018 MB46_00255 12297e3b75b9756f7884a9555b4b8eaa 404 Pfam PF00331 Glycosyl hydrolase family 10 72 347 3.4E-27 T 14-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 MB46_04665 d76154c71a2b7bd19589d9e45ac34f4f 250 Pfam PF02565 Recombination protein O C terminal 93 244 9.5E-29 T 14-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 MB46_04665 d76154c71a2b7bd19589d9e45ac34f4f 250 Hamap MF_00201 DNA repair protein RecO [recO]. 9 250 25.325 T 14-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 MB46_04665 d76154c71a2b7bd19589d9e45ac34f4f 250 Gene3D G3DSA:2.40.50.140 7 88 1.8E-26 T 14-10-2018 MB46_04665 d76154c71a2b7bd19589d9e45ac34f4f 250 TIGRFAM TIGR00613 reco: DNA repair protein RecO 12 245 1.2E-30 T 14-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 MB46_04665 d76154c71a2b7bd19589d9e45ac34f4f 250 SUPERFAMILY SSF50249 9 84 4.28E-19 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold MB46_04665 d76154c71a2b7bd19589d9e45ac34f4f 250 Pfam PF11967 Recombination protein O N terminal 10 85 3.4E-23 T 14-10-2018 IPR022572 DNA replication/recombination mediator RecO, N-terminal MB46_04665 d76154c71a2b7bd19589d9e45ac34f4f 250 SUPERFAMILY SSF57863 90 239 4.18E-36 T 14-10-2018 IPR037278 ARFGAP/RecO-like zinc finger MB46_03535 0a183341b992eb8bbdc7dbb5e146002c 411 SMART SM00387 301 406 2.0E-5 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MB46_03535 0a183341b992eb8bbdc7dbb5e146002c 411 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 308 404 5.8E-8 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MB46_03535 0a183341b992eb8bbdc7dbb5e146002c 411 Gene3D G3DSA:3.30.565.10 263 406 3.1E-17 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MB46_03535 0a183341b992eb8bbdc7dbb5e146002c 411 Pfam PF06580 Histidine kinase 208 286 8.8E-24 T 14-10-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 MB46_03535 0a183341b992eb8bbdc7dbb5e146002c 411 SUPERFAMILY SSF55874 264 403 2.62E-16 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MB46_13335 a8437ee921c66aaf7d6f1ecba3fc6ec3 189 ProSitePatterns PS00113 Adenylate kinase signature. 82 93 - T 14-10-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 MB46_13335 a8437ee921c66aaf7d6f1ecba3fc6ec3 189 Pfam PF00406 Adenylate kinase 6 164 1.3E-49 T 14-10-2018 MB46_13335 a8437ee921c66aaf7d6f1ecba3fc6ec3 189 Hamap MF_00235 Adenylate kinase [adk]. 2 187 41.002 T 14-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 MB46_13335 a8437ee921c66aaf7d6f1ecba3fc6ec3 189 PRINTS PR00094 Adenylate kinase signature 134 149 1.3E-29 T 14-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 MB46_13335 a8437ee921c66aaf7d6f1ecba3fc6ec3 189 PRINTS PR00094 Adenylate kinase signature 33 47 1.3E-29 T 14-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 MB46_13335 a8437ee921c66aaf7d6f1ecba3fc6ec3 189 PRINTS PR00094 Adenylate kinase signature 82 98 1.3E-29 T 14-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 MB46_13335 a8437ee921c66aaf7d6f1ecba3fc6ec3 189 PRINTS PR00094 Adenylate kinase signature 151 165 1.3E-29 T 14-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 MB46_13335 a8437ee921c66aaf7d6f1ecba3fc6ec3 189 PRINTS PR00094 Adenylate kinase signature 5 18 1.3E-29 T 14-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 MB46_13335 a8437ee921c66aaf7d6f1ecba3fc6ec3 189 Gene3D G3DSA:3.40.50.300 1 189 9.6E-61 T 14-10-2018 MB46_13335 a8437ee921c66aaf7d6f1ecba3fc6ec3 189 SUPERFAMILY SSF52540 2 187 4.27E-41 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_14310 39589ab5868b97e5bf6b6b18e210af23 445 Pfam PF00425 chorismate binding enzyme 176 431 6.0E-65 T 14-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal MB46_14310 39589ab5868b97e5bf6b6b18e210af23 445 TIGRFAM TIGR00543 isochor_syn: isochorismate synthase 97 439 1.5E-76 T 14-10-2018 IPR004561 Isochorismate synthase GO:0008909|GO:0009058 KEGG: 00130+5.4.4.2|MetaCyc: PWY-5837|MetaCyc: PWY-5901|MetaCyc: PWY-6406 MB46_14310 39589ab5868b97e5bf6b6b18e210af23 445 Gene3D G3DSA:3.60.120.10 27 443 1.5E-89 T 14-10-2018 IPR005801 ADC synthase GO:0009058 MB46_14310 39589ab5868b97e5bf6b6b18e210af23 445 SUPERFAMILY SSF56322 41 441 7.85E-82 T 14-10-2018 IPR005801 ADC synthase GO:0009058 MB46_14750 6fa7210e9504c5f64c984dffed58d121 306 SUPERFAMILY SSF55620 146 300 2.82E-55 T 14-10-2018 MB46_14750 6fa7210e9504c5f64c984dffed58d121 306 SUPERFAMILY SSF55620 10 136 1.19E-47 T 14-10-2018 MB46_14750 6fa7210e9504c5f64c984dffed58d121 306 Gene3D G3DSA:3.10.270.10 1 306 6.3E-115 T 14-10-2018 MB46_14750 6fa7210e9504c5f64c984dffed58d121 306 ProSitePatterns PS00366 Uricase signature. 154 181 - T 14-10-2018 IPR019842 Uricase, conserved site GO:0004846|GO:0006144|GO:0055114 KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 MB46_14750 6fa7210e9504c5f64c984dffed58d121 306 ProDom PD003367 URICASE OXIDOREDUCTASE URATE OXIDASE METABOLISM PURINE PEROXISOME ACETYLATION II DIRECT 184 289 1.0E-45 T 14-10-2018 MB46_14750 6fa7210e9504c5f64c984dffed58d121 306 TIGRFAM TIGR03383 urate_oxi: urate oxidase 12 289 5.4E-109 T 14-10-2018 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 MB46_14750 6fa7210e9504c5f64c984dffed58d121 306 PIRSF PIRSF000241 1 295 5.2E-97 T 14-10-2018 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 MB46_14750 6fa7210e9504c5f64c984dffed58d121 306 Pfam PF01014 Uricase 16 138 1.9E-20 T 14-10-2018 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 MB46_14750 6fa7210e9504c5f64c984dffed58d121 306 Pfam PF01014 Uricase 149 284 3.2E-29 T 14-10-2018 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 MB46_14750 6fa7210e9504c5f64c984dffed58d121 306 PRINTS PR00093 Uricase signature 18 29 3.3E-20 T 14-10-2018 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 MB46_14750 6fa7210e9504c5f64c984dffed58d121 306 PRINTS PR00093 Uricase signature 92 105 3.3E-20 T 14-10-2018 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 MB46_14750 6fa7210e9504c5f64c984dffed58d121 306 PRINTS PR00093 Uricase signature 154 170 3.3E-20 T 14-10-2018 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 MB46_14750 6fa7210e9504c5f64c984dffed58d121 306 PRINTS PR00093 Uricase signature 170 182 3.3E-20 T 14-10-2018 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 MB46_14750 6fa7210e9504c5f64c984dffed58d121 306 PRINTS PR00093 Uricase signature 57 71 3.3E-20 T 14-10-2018 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 MB46_12085 498475bca66808f99f94351400acb11a 267 Gene3D G3DSA:3.40.190.10 36 261 6.5E-85 T 14-10-2018 MB46_12085 498475bca66808f99f94351400acb11a 267 PIRSF PIRSF002854 1 267 1.4E-85 T 14-10-2018 IPR004872 Lipoprotein NlpA family MB46_12085 498475bca66808f99f94351400acb11a 267 SUPERFAMILY SSF53850 34 266 2.54E-69 T 14-10-2018 MB46_12085 498475bca66808f99f94351400acb11a 267 Gene3D G3DSA:3.40.190.10 117 218 6.5E-85 T 14-10-2018 MB46_12085 498475bca66808f99f94351400acb11a 267 Pfam PF03180 NLPA lipoprotein 35 266 3.0E-79 T 14-10-2018 IPR004872 Lipoprotein NlpA family MB46_08155 a4b741f445ac8ab1a52f6e915bd3b0e5 292 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 208 226 - T 14-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 MB46_08155 a4b741f445ac8ab1a52f6e915bd3b0e5 292 Hamap MF_01974 Methionine aminopeptidase [map]. 45 292 38.357 T 14-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 MB46_08155 a4b741f445ac8ab1a52f6e915bd3b0e5 292 SUPERFAMILY SSF55920 8 291 4.71E-81 T 14-10-2018 IPR036005 Creatinase/aminopeptidase-like MB46_08155 a4b741f445ac8ab1a52f6e915bd3b0e5 292 Pfam PF00557 Metallopeptidase family M24 54 283 4.0E-48 T 14-10-2018 IPR000994 Peptidase M24 MB46_08155 a4b741f445ac8ab1a52f6e915bd3b0e5 292 Gene3D G3DSA:3.90.230.10 10 292 1.3E-105 T 14-10-2018 MB46_08155 a4b741f445ac8ab1a52f6e915bd3b0e5 292 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 47 290 1.9E-87 T 14-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 MB46_08155 a4b741f445ac8ab1a52f6e915bd3b0e5 292 PRINTS PR00599 Methionine aminopeptidase-1 signature 202 214 2.0E-21 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 MB46_08155 a4b741f445ac8ab1a52f6e915bd3b0e5 292 PRINTS PR00599 Methionine aminopeptidase-1 signature 132 148 2.0E-21 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 MB46_08155 a4b741f445ac8ab1a52f6e915bd3b0e5 292 PRINTS PR00599 Methionine aminopeptidase-1 signature 234 246 2.0E-21 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 MB46_08155 a4b741f445ac8ab1a52f6e915bd3b0e5 292 PRINTS PR00599 Methionine aminopeptidase-1 signature 110 123 2.0E-21 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 MB46_08995 152933c5b2d3d38ca1f036e3249276bc 460 PIRSF PIRSF001563 5 454 6.2E-110 T 14-10-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 MB46_08995 152933c5b2d3d38ca1f036e3249276bc 460 SUPERFAMILY SSF53244 309 449 1.83E-23 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MB46_08995 152933c5b2d3d38ca1f036e3249276bc 460 TIGRFAM TIGR01499 folC: bifunctional protein FolC 36 448 1.2E-102 T 14-10-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 MB46_08995 152933c5b2d3d38ca1f036e3249276bc 460 Pfam PF02875 Mur ligase family, glutamate ligase domain 309 369 1.2E-9 T 14-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 MB46_08995 152933c5b2d3d38ca1f036e3249276bc 460 Pfam PF08245 Mur ligase middle domain 52 282 3.2E-14 T 14-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 MB46_08995 152933c5b2d3d38ca1f036e3249276bc 460 Gene3D G3DSA:3.90.190.20 310 454 1.1E-30 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MB46_08995 152933c5b2d3d38ca1f036e3249276bc 460 SUPERFAMILY SSF53623 10 305 1.93E-86 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 MB46_08995 152933c5b2d3d38ca1f036e3249276bc 460 Gene3D G3DSA:3.40.1190.10 7 309 7.4E-91 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 MB46_04305 f4307f9f64b063c45a9c46198f0bc297 445 Pfam PF01168 Alanine racemase, N-terminal domain 61 250 9.9E-8 T 14-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MB46_04305 f4307f9f64b063c45a9c46198f0bc297 445 SUPERFAMILY SSF51419 61 275 1.74E-19 T 14-10-2018 IPR029066 PLP-binding barrel MB46_04305 f4307f9f64b063c45a9c46198f0bc297 445 SMART SM01119 330 429 3.7E-31 T 14-10-2018 IPR026956 D-serine dehydratase-like domain MB46_04305 f4307f9f64b063c45a9c46198f0bc297 445 Gene3D G3DSA:3.20.20.10 63 306 2.8E-118 T 14-10-2018 IPR029066 PLP-binding barrel MB46_04305 f4307f9f64b063c45a9c46198f0bc297 445 Pfam PF14031 Putative serine dehydratase domain 330 427 1.0E-14 T 14-10-2018 IPR026956 D-serine dehydratase-like domain MB46_04305 f4307f9f64b063c45a9c46198f0bc297 445 Gene3D G3DSA:2.40.37.20 50 445 2.8E-118 T 14-10-2018 MB46_00390 6da7525cb2478e5b8c11ae564a646fcb 352 Gene3D G3DSA:3.40.50.1980 46 187 3.7E-41 T 14-10-2018 MB46_00390 6da7525cb2478e5b8c11ae564a646fcb 352 Pfam PF01497 Periplasmic binding protein 69 315 1.4E-23 T 14-10-2018 IPR002491 ABC transporter periplasmic binding domain MB46_00390 6da7525cb2478e5b8c11ae564a646fcb 352 Gene3D G3DSA:3.40.50.1980 189 352 2.5E-36 T 14-10-2018 MB46_00390 6da7525cb2478e5b8c11ae564a646fcb 352 SUPERFAMILY SSF53807 46 319 2.63E-42 T 14-10-2018 MB46_08390 a5de686b3e08cb89d4025a99102d3edd 128 Gene3D G3DSA:2.40.50.100 2 128 7.7E-46 T 14-10-2018 MB46_08390 a5de686b3e08cb89d4025a99102d3edd 128 Pfam PF01597 Glycine cleavage H-protein 8 126 2.1E-40 T 14-10-2018 IPR033753 Glycine cleavage system H-protein/Simiate MB46_08390 a5de686b3e08cb89d4025a99102d3edd 128 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 3 126 1.8E-42 T 14-10-2018 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 MB46_08390 a5de686b3e08cb89d4025a99102d3edd 128 SUPERFAMILY SSF51230 3 127 4.58E-41 T 14-10-2018 IPR011053 Single hybrid motif MB46_08390 a5de686b3e08cb89d4025a99102d3edd 128 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 50 79 - T 14-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 MB46_08390 a5de686b3e08cb89d4025a99102d3edd 128 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 5 128 36.627 T 14-10-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 MB46_00655 02a1a3793af17039dc9f1e5ef99685cd 250 Pfam PF06724 Domain of Unknown Function (DUF1206) 179 246 3.3E-16 T 14-10-2018 IPR009597 Domain of unknown function DUF1206 MB46_00655 02a1a3793af17039dc9f1e5ef99685cd 250 Pfam PF06724 Domain of Unknown Function (DUF1206) 7 71 2.3E-15 T 14-10-2018 IPR009597 Domain of unknown function DUF1206 MB46_00655 02a1a3793af17039dc9f1e5ef99685cd 250 Pfam PF06724 Domain of Unknown Function (DUF1206) 90 155 9.8E-12 T 14-10-2018 IPR009597 Domain of unknown function DUF1206 MB46_12315 cfa9d507ee383f5d5b4cb8131b8cbcae 254 Pfam PF00005 ABC transporter 21 179 4.7E-31 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_12315 cfa9d507ee383f5d5b4cb8131b8cbcae 254 ProSitePatterns PS00211 ABC transporters family signature. 151 165 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_12315 cfa9d507ee383f5d5b4cb8131b8cbcae 254 Gene3D G3DSA:3.40.50.300 1 253 4.3E-75 T 14-10-2018 MB46_12315 cfa9d507ee383f5d5b4cb8131b8cbcae 254 SUPERFAMILY SSF52540 5 249 1.14E-74 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_12315 cfa9d507ee383f5d5b4cb8131b8cbcae 254 SMART SM00382 30 227 3.9E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_12315 cfa9d507ee383f5d5b4cb8131b8cbcae 254 PIRSF PIRSF039085 2 254 4.7E-115 T 14-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 MB46_04115 2493b1dd7b1947c9ffe96ece73a3efcc 1293 SUPERFAMILY SSF51161 841 1046 6.38E-15 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily MB46_04115 2493b1dd7b1947c9ffe96ece73a3efcc 1293 Pfam PF00501 AMP-binding enzyme 18 394 9.2E-67 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 MB46_04115 2493b1dd7b1947c9ffe96ece73a3efcc 1293 SUPERFAMILY SSF47336 505 567 3.93E-11 T 14-10-2018 IPR036736 ACP-like superfamily MB46_04115 2493b1dd7b1947c9ffe96ece73a3efcc 1293 SUPERFAMILY SSF56801 9 517 2.62E-112 T 14-10-2018 MB46_04115 2493b1dd7b1947c9ffe96ece73a3efcc 1293 Gene3D G3DSA:1.10.1200.10 501 573 1.1E-12 T 14-10-2018 IPR036736 ACP-like superfamily MB46_04115 2493b1dd7b1947c9ffe96ece73a3efcc 1293 Gene3D G3DSA:2.160.10.10 704 819 6.5E-14 T 14-10-2018 MB46_04115 2493b1dd7b1947c9ffe96ece73a3efcc 1293 SUPERFAMILY SSF51161 701 812 2.77E-19 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily MB46_04115 2493b1dd7b1947c9ffe96ece73a3efcc 1293 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 761 794 1.1E-4 T 14-10-2018 IPR001451 Hexapeptide repeat MB46_04115 2493b1dd7b1947c9ffe96ece73a3efcc 1293 ProSitePatterns PS00455 Putative AMP-binding domain signature. 147 158 - T 14-10-2018 IPR020845 AMP-binding, conserved site MB46_04115 2493b1dd7b1947c9ffe96ece73a3efcc 1293 SMART SM00823 Phosphopantetheine attachment site 505 573 8.7E-4 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MB46_04115 2493b1dd7b1947c9ffe96ece73a3efcc 1293 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 38 418 1.2E-97 T 14-10-2018 IPR010071 Amino acid adenylation domain MB46_04115 2493b1dd7b1947c9ffe96ece73a3efcc 1293 SUPERFAMILY SSF51161 1172 1285 9.29E-14 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily MB46_04115 2493b1dd7b1947c9ffe96ece73a3efcc 1293 Gene3D G3DSA:3.30.300.30 390 490 1.7E-21 T 14-10-2018 MB46_04115 2493b1dd7b1947c9ffe96ece73a3efcc 1293 TIGRFAM TIGR02353 NRPS_term_dom: non-ribosomal peptide synthetase terminal domain of unknown function 595 1281 7.1E-210 T 14-10-2018 IPR012728 Non-ribosomal peptide synthetase, C-terminal MB46_04115 2493b1dd7b1947c9ffe96ece73a3efcc 1293 Pfam PF00550 Phosphopantetheine attachment site 506 567 5.0E-9 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain MB46_04115 2493b1dd7b1947c9ffe96ece73a3efcc 1293 Gene3D G3DSA:3.40.50.12780 5 389 7.0E-92 T 14-10-2018 MB46_04115 2493b1dd7b1947c9ffe96ece73a3efcc 1293 Gene3D G3DSA:2.160.10.10 1181 1288 5.0E-7 T 14-10-2018 MB46_04115 2493b1dd7b1947c9ffe96ece73a3efcc 1293 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 768 796 - T 14-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 MB46_19985 6b2d56f5f9dd21f579eca2c8c6fc2e26 219 SUPERFAMILY SSF53474 3 195 4.78E-31 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_19985 6b2d56f5f9dd21f579eca2c8c6fc2e26 219 Gene3D G3DSA:3.40.50.1820 2 203 6.7E-33 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_19985 6b2d56f5f9dd21f579eca2c8c6fc2e26 219 Pfam PF00975 Thioesterase domain 6 188 4.5E-18 T 14-10-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 MB46_19185 6b2d56f5f9dd21f579eca2c8c6fc2e26 219 SUPERFAMILY SSF53474 3 195 4.78E-31 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_19185 6b2d56f5f9dd21f579eca2c8c6fc2e26 219 Gene3D G3DSA:3.40.50.1820 2 203 6.7E-33 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_19185 6b2d56f5f9dd21f579eca2c8c6fc2e26 219 Pfam PF00975 Thioesterase domain 6 188 4.5E-18 T 14-10-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 MB46_08680 99e4ab856e42f708e39a441eb89464e0 251 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 237 1.4E-92 T 14-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MB46_08680 99e4ab856e42f708e39a441eb89464e0 251 Gene3D G3DSA:3.30.70.980 134 206 2.9E-54 T 14-10-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MB46_08680 99e4ab856e42f708e39a441eb89464e0 251 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 3 240 33.962 T 14-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MB46_08680 99e4ab856e42f708e39a441eb89464e0 251 Gene3D G3DSA:3.30.70.980 86 236 2.9E-54 T 14-10-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MB46_08680 99e4ab856e42f708e39a441eb89464e0 251 Gene3D G3DSA:1.10.10.200 1 80 1.5E-28 T 14-10-2018 IPR017856 Integrase-like, N-terminal MB46_08680 99e4ab856e42f708e39a441eb89464e0 251 SUPERFAMILY SSF75625 3 246 9.55E-87 T 14-10-2018 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MB46_08680 99e4ab856e42f708e39a441eb89464e0 251 Pfam PF01709 Transcriptional regulator 5 237 1.7E-88 T 14-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MB46_05040 872f6bafa46c78477aaf9a65736a32ff 313 Gene3D G3DSA:3.40.50.300 5 174 3.0E-6 T 14-10-2018 MB46_05040 872f6bafa46c78477aaf9a65736a32ff 313 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 29 312 39.121 T 14-10-2018 IPR005337 RapZ-like family GO:0005524 MB46_05040 872f6bafa46c78477aaf9a65736a32ff 313 SUPERFAMILY SSF52540 28 182 3.04E-14 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_05040 872f6bafa46c78477aaf9a65736a32ff 313 Pfam PF03668 P-loop ATPase protein family 30 313 1.3E-98 T 14-10-2018 IPR005337 RapZ-like family GO:0005524 MB46_05040 872f6bafa46c78477aaf9a65736a32ff 313 PIRSF PIRSF005052 29 313 2.2E-101 T 14-10-2018 IPR005337 RapZ-like family GO:0005524 MB46_05920 b46f80561c3dcc66dd57eee8990e0790 499 SUPERFAMILY SSF103473 15 485 1.7E-65 T 14-10-2018 IPR036259 MFS transporter superfamily MB46_05920 b46f80561c3dcc66dd57eee8990e0790 499 Gene3D G3DSA:1.20.1250.20 288 488 9.0E-20 T 14-10-2018 MB46_05920 b46f80561c3dcc66dd57eee8990e0790 499 Gene3D G3DSA:1.20.1720.10 33 251 4.5E-41 T 14-10-2018 MB46_05920 b46f80561c3dcc66dd57eee8990e0790 499 ProSitePatterns PS00216 Sugar transport proteins signature 1. 86 102 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MB46_05920 b46f80561c3dcc66dd57eee8990e0790 499 Pfam PF07690 Major Facilitator Superfamily 38 430 5.4E-49 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MB46_00160 44ec5d172af0aeb7ee059420a757e9ea 319 SUPERFAMILY SSF52540 14 262 1.69E-66 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_00160 44ec5d172af0aeb7ee059420a757e9ea 319 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 242 276 5.0E-7 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MB46_00160 44ec5d172af0aeb7ee059420a757e9ea 319 Pfam PF00005 ABC transporter 35 190 2.0E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_00160 44ec5d172af0aeb7ee059420a757e9ea 319 SMART SM00382 43 240 1.5E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_00160 44ec5d172af0aeb7ee059420a757e9ea 319 Gene3D G3DSA:3.40.50.300 12 293 3.8E-83 T 14-10-2018 MB46_00160 44ec5d172af0aeb7ee059420a757e9ea 319 ProSitePatterns PS00211 ABC transporters family signature. 163 177 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_11625 64e01ecd712713bc332efb3dd4766df0 232 Pfam PF16321 Sigma 54 modulation/S30EA ribosomal protein C terminus 153 207 1.5E-18 T 14-10-2018 IPR032528 Sigma 54 modulation/S30EA ribosomal protein, C-terminal MB46_11625 64e01ecd712713bc332efb3dd4766df0 232 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 5 99 3.2E-19 T 14-10-2018 IPR003489 Ribosome hibernation promoting factor/RaiA GO:0044238 MB46_11625 64e01ecd712713bc332efb3dd4766df0 232 Hamap MF_00839 Ribosome hibernation promoting factor [hpf]. 1 211 20.211 T 14-10-2018 IPR034694 Ribosome hibernation promoting factor, long/plastid MB46_11625 64e01ecd712713bc332efb3dd4766df0 232 Gene3D G3DSA:3.30.505.50 166 211 4.2E-16 T 14-10-2018 IPR038416 Sigma 54 modulation/S30EA ribosomal protein, C-terminal domain superfamily MB46_11625 64e01ecd712713bc332efb3dd4766df0 232 SUPERFAMILY SSF69754 3 110 9.81E-23 T 14-10-2018 IPR036567 Ribosome hibernation promotion factor-like MB46_11625 64e01ecd712713bc332efb3dd4766df0 232 Gene3D G3DSA:3.30.160.100 2 105 2.6E-21 T 14-10-2018 IPR036567 Ribosome hibernation promotion factor-like MB46_11625 64e01ecd712713bc332efb3dd4766df0 232 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 1 103 2.5E-21 T 14-10-2018 IPR003489 Ribosome hibernation promoting factor/RaiA GO:0044238 MB46_14860 12de7baf3b4011b9f513257cf48d4caa 318 SUPERFAMILY SSF47005 8 47 9.55E-11 T 14-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 MB46_14860 12de7baf3b4011b9f513257cf48d4caa 318 Gene3D G3DSA:3.30.559.10 62 314 1.0E-79 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 MB46_14860 12de7baf3b4011b9f513257cf48d4caa 318 TIGRFAM TIGR02927 SucB_Actino: 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase 6 318 4.5E-131 T 14-10-2018 IPR014276 2-oxoglutarate dehydrogenase, E2 component KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00620+2.3.1.12 MB46_14860 12de7baf3b4011b9f513257cf48d4caa 318 Pfam PF02817 e3 binding domain 11 44 1.2E-12 T 14-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 MB46_14860 12de7baf3b4011b9f513257cf48d4caa 318 Gene3D G3DSA:4.10.320.10 6 49 8.3E-14 T 14-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 MB46_14860 12de7baf3b4011b9f513257cf48d4caa 318 SUPERFAMILY SSF52777 72 308 1.42E-75 T 14-10-2018 MB46_14860 12de7baf3b4011b9f513257cf48d4caa 318 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 82 308 2.5E-73 T 14-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 MB46_01160 4e188a2d4d2eba93724ac19f6f56d409 360 PRINTS PR00116 Arginase signature 128 143 6.2E-14 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 MB46_01160 4e188a2d4d2eba93724ac19f6f56d409 360 PRINTS PR00116 Arginase signature 242 271 6.2E-14 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 MB46_01160 4e188a2d4d2eba93724ac19f6f56d409 360 Gene3D G3DSA:3.40.800.10 11 322 2.2E-109 T 14-10-2018 MB46_01160 4e188a2d4d2eba93724ac19f6f56d409 360 ProSitePatterns PS01053 Arginase family signature. 245 266 - T 14-10-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 MB46_01160 4e188a2d4d2eba93724ac19f6f56d409 360 Pfam PF00491 Arginase family 41 313 2.6E-89 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 MB46_01160 4e188a2d4d2eba93724ac19f6f56d409 360 TIGRFAM TIGR01230 agmatinase: agmatinase 38 314 5.8E-65 T 14-10-2018 IPR005925 Agmatinase-related KEGG: 00330+3.5.3.11|MetaCyc: PWY-40|MetaCyc: PWY-6305|Reactome: R-HSA-351143 MB46_01160 4e188a2d4d2eba93724ac19f6f56d409 360 PIRSF PIRSF036979 22 321 5.7E-115 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 MB46_01160 4e188a2d4d2eba93724ac19f6f56d409 360 SUPERFAMILY SSF52768 21 318 2.88E-96 T 14-10-2018 IPR023696 Ureohydrolase domain superfamily MB46_17555 cc73a17f7d749f0b1920b92af3e74aaf 683 Gene3D G3DSA:3.20.20.80 21 412 4.9E-136 T 14-10-2018 MB46_17555 cc73a17f7d749f0b1920b92af3e74aaf 683 Pfam PF08533 Beta-galactosidase C-terminal domain 628 680 1.1E-5 T 14-10-2018 IPR013739 Beta-galactosidase C-terminal GO:0004565|GO:0006012 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 MB46_17555 cc73a17f7d749f0b1920b92af3e74aaf 683 PIRSF PIRSF001084 23 683 1.1E-262 T 14-10-2018 IPR003476 Glycoside hydrolase, family 42 GO:0004565|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 MB46_17555 cc73a17f7d749f0b1920b92af3e74aaf 683 SUPERFAMILY SSF51445 32 389 1.89E-111 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily MB46_17555 cc73a17f7d749f0b1920b92af3e74aaf 683 Pfam PF08532 Beta-galactosidase trimerisation domain 419 619 6.0E-52 T 14-10-2018 IPR013738 Beta-galactosidase trimerisation GO:0004565|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 MB46_17555 cc73a17f7d749f0b1920b92af3e74aaf 683 Gene3D G3DSA:2.60.40.1180 627 682 2.5E-8 T 14-10-2018 IPR013780 Glycosyl hydrolase, all-beta MB46_17555 cc73a17f7d749f0b1920b92af3e74aaf 683 Gene3D G3DSA:3.40.50.880 415 624 2.2E-58 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like MB46_17555 cc73a17f7d749f0b1920b92af3e74aaf 683 Pfam PF02449 Beta-galactosidase 36 407 2.1E-154 T 14-10-2018 IPR013529 Glycoside hydrolase, family 42, N-terminal GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 MB46_17555 cc73a17f7d749f0b1920b92af3e74aaf 683 SUPERFAMILY SSF52317 415 619 1.14E-53 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like MB46_13520 130761e600fc06328ca726997978f553 143 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 5 142 2.9E-61 T 14-10-2018 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_13520 130761e600fc06328ca726997978f553 143 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 7 143 30.082 T 14-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 MB46_13520 130761e600fc06328ca726997978f553 143 Gene3D G3DSA:1.10.10.250 74 142 5.9E-26 T 14-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily MB46_13520 130761e600fc06328ca726997978f553 143 Pfam PF03946 Ribosomal protein L11, N-terminal domain 11 68 3.1E-28 T 14-10-2018 IPR020784 Ribosomal protein L11, N-terminal MB46_13520 130761e600fc06328ca726997978f553 143 SUPERFAMILY SSF54747 4 74 2.09E-29 T 14-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily MB46_13520 130761e600fc06328ca726997978f553 143 Gene3D G3DSA:3.30.1550.10 4 73 3.5E-33 T 14-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily MB46_13520 130761e600fc06328ca726997978f553 143 SUPERFAMILY SSF46906 69 142 1.09E-24 T 14-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily MB46_13520 130761e600fc06328ca726997978f553 143 Pfam PF00298 Ribosomal protein L11, RNA binding domain 73 141 9.8E-23 T 14-10-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 MB46_13520 130761e600fc06328ca726997978f553 143 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 38 75 6.0E-16 T 14-10-2018 MB46_13520 130761e600fc06328ca726997978f553 143 ProSitePatterns PS00359 Ribosomal protein L11 signature. 128 142 - T 14-10-2018 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MB46_13520 130761e600fc06328ca726997978f553 143 SMART SM00649 11 142 1.9E-79 T 14-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 MB46_12275 a2c7066b758a76261e5624e50f1843f4 293 Gene3D G3DSA:3.40.50.170 97 292 1.1E-72 T 14-10-2018 MB46_12275 a2c7066b758a76261e5624e50f1843f4 293 TIGRFAM TIGR00655 PurU: formyltetrahydrofolate deformylase 15 292 1.2E-97 T 14-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 MB46_12275 a2c7066b758a76261e5624e50f1843f4 293 Hamap MF_01927 Formyltetrahydrofolate deformylase [purU]. 11 292 44.759 T 14-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 MB46_12275 a2c7066b758a76261e5624e50f1843f4 293 PIRSF PIRSF036480 12 293 1.4E-108 T 14-10-2018 MB46_12275 a2c7066b758a76261e5624e50f1843f4 293 Gene3D G3DSA:3.30.70.260 8 95 1.0E-24 T 14-10-2018 MB46_12275 a2c7066b758a76261e5624e50f1843f4 293 SUPERFAMILY SSF53328 98 292 3.01E-63 T 14-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MB46_12275 a2c7066b758a76261e5624e50f1843f4 293 Pfam PF00551 Formyl transferase 98 274 7.2E-42 T 14-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MB46_12275 a2c7066b758a76261e5624e50f1843f4 293 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 244 266 2.3E-50 T 14-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 MB46_12275 a2c7066b758a76261e5624e50f1843f4 293 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 48 60 2.3E-50 T 14-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 MB46_12275 a2c7066b758a76261e5624e50f1843f4 293 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 98 120 2.3E-50 T 14-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 MB46_12275 a2c7066b758a76261e5624e50f1843f4 293 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 266 291 2.3E-50 T 14-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 MB46_12275 a2c7066b758a76261e5624e50f1843f4 293 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 120 147 2.3E-50 T 14-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 MB46_12275 a2c7066b758a76261e5624e50f1843f4 293 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 16 42 2.3E-50 T 14-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 MB46_12275 a2c7066b758a76261e5624e50f1843f4 293 SUPERFAMILY SSF55021 12 96 4.43E-14 T 14-10-2018 MB46_07615 b5fc1aa65da40740d3a814353507818b 484 Gene3D G3DSA:3.50.50.60 250 398 7.1E-34 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_07615 b5fc1aa65da40740d3a814353507818b 484 SUPERFAMILY SSF51971 381 468 6.0E-9 T 14-10-2018 MB46_07615 b5fc1aa65da40740d3a814353507818b 484 SUPERFAMILY SSF51971 143 399 1.06E-67 T 14-10-2018 MB46_07615 b5fc1aa65da40740d3a814353507818b 484 PRINTS PR00419 Adrenodoxin reductase family signature 285 299 1.6E-24 T 14-10-2018 MB46_07615 b5fc1aa65da40740d3a814353507818b 484 PRINTS PR00419 Adrenodoxin reductase family signature 146 168 1.6E-24 T 14-10-2018 MB46_07615 b5fc1aa65da40740d3a814353507818b 484 PRINTS PR00419 Adrenodoxin reductase family signature 169 182 1.6E-24 T 14-10-2018 MB46_07615 b5fc1aa65da40740d3a814353507818b 484 PRINTS PR00419 Adrenodoxin reductase family signature 211 221 1.6E-24 T 14-10-2018 MB46_07615 b5fc1aa65da40740d3a814353507818b 484 Gene3D G3DSA:1.10.1060.10 3 141 5.0E-20 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 MB46_07615 b5fc1aa65da40740d3a814353507818b 484 TIGRFAM TIGR01317 GOGAT_sm_gam: glutamate synthase, NADH/NADPH, small subunit 3 472 4.1E-199 T 14-10-2018 IPR006005 Glutamate synthase, NADH/NADPH, small subunit 1 GO:0006537|GO:0016639|GO:0055114 MB46_07615 b5fc1aa65da40740d3a814353507818b 484 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 25 132 1.4E-21 T 14-10-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 MB46_07615 b5fc1aa65da40740d3a814353507818b 484 Gene3D G3DSA:3.40.50.720 142 249 4.4E-17 T 14-10-2018 MB46_07615 b5fc1aa65da40740d3a814353507818b 484 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 146 454 1.2E-24 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MB46_07615 b5fc1aa65da40740d3a814353507818b 484 SUPERFAMILY SSF46548 12 155 3.4E-34 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 MB46_05015 9cdb0e0a59af996528803a04d0083b06 124 SUPERFAMILY SSF46785 11 93 8.0E-17 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_05015 9cdb0e0a59af996528803a04d0083b06 124 Gene3D G3DSA:1.10.10.10 6 82 4.4E-18 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_05015 9cdb0e0a59af996528803a04d0083b06 124 Pfam PF00392 Bacterial regulatory proteins, gntR family 20 81 2.7E-14 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MB46_05015 9cdb0e0a59af996528803a04d0083b06 124 SMART SM00345 22 81 2.1E-11 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MB46_01355 b0924afd6ed69380aae205162acf1b70 705 Pfam PF00005 ABC transporter 401 550 1.9E-33 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_01355 b0924afd6ed69380aae205162acf1b70 705 Pfam PF00005 ABC transporter 42 199 6.7E-22 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_01355 b0924afd6ed69380aae205162acf1b70 705 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 251 316 3.8E-17 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MB46_01355 b0924afd6ed69380aae205162acf1b70 705 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 602 664 3.5E-15 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MB46_01355 b0924afd6ed69380aae205162acf1b70 705 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 249 329 5.8E-21 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MB46_01355 b0924afd6ed69380aae205162acf1b70 705 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 600 694 6.7E-20 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MB46_01355 b0924afd6ed69380aae205162acf1b70 705 ProSitePatterns PS00211 ABC transporters family signature. 172 186 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_01355 b0924afd6ed69380aae205162acf1b70 705 Gene3D G3DSA:3.40.50.300 19 351 2.9E-90 T 14-10-2018 MB46_01355 b0924afd6ed69380aae205162acf1b70 705 Gene3D G3DSA:3.40.50.300 371 703 1.9E-96 T 14-10-2018 MB46_01355 b0924afd6ed69380aae205162acf1b70 705 ProSitePatterns PS00211 ABC transporters family signature. 523 537 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_01355 b0924afd6ed69380aae205162acf1b70 705 SMART SM00382 409 600 6.5E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_01355 b0924afd6ed69380aae205162acf1b70 705 SMART SM00382 50 257 2.2E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_01355 b0924afd6ed69380aae205162acf1b70 705 SUPERFAMILY SSF52540 21 269 8.99E-63 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_01355 b0924afd6ed69380aae205162acf1b70 705 SUPERFAMILY SSF52540 390 622 4.31E-74 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_19610 243aebc91ea3d23f36c68c90448a5f74 2890 Pfam PF04851 Type III restriction enzyme, res subunit 830 1021 6.1E-6 T 14-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 MB46_19610 243aebc91ea3d23f36c68c90448a5f74 2890 SMART SM00487 828 1110 9.2E-7 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MB46_19610 243aebc91ea3d23f36c68c90448a5f74 2890 SUPERFAMILY SSF53335 63 257 6.23E-30 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MB46_19610 243aebc91ea3d23f36c68c90448a5f74 2890 SUPERFAMILY SSF52540 788 1120 5.32E-26 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_19610 243aebc91ea3d23f36c68c90448a5f74 2890 Pfam PF00271 Helicase conserved C-terminal domain 1303 1374 1.6E-5 T 14-10-2018 IPR001650 Helicase, C-terminal MB46_19610 243aebc91ea3d23f36c68c90448a5f74 2890 SUPERFAMILY SSF52540 1009 1420 4.68E-23 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_19610 243aebc91ea3d23f36c68c90448a5f74 2890 Gene3D G3DSA:3.40.50.300 1269 1410 9.3E-21 T 14-10-2018 MB46_19610 243aebc91ea3d23f36c68c90448a5f74 2890 Gene3D G3DSA:3.40.50.150 73 268 3.0E-21 T 14-10-2018 MB46_19610 243aebc91ea3d23f36c68c90448a5f74 2890 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 153 165 8.4E-6 T 14-10-2018 MB46_19610 243aebc91ea3d23f36c68c90448a5f74 2890 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 96 110 8.4E-6 T 14-10-2018 MB46_19610 243aebc91ea3d23f36c68c90448a5f74 2890 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 178 202 8.4E-6 T 14-10-2018 MB46_16330 86cd7e51617166d51d7b1d63bc54647b 313 Pfam PF03466 LysR substrate binding domain 91 292 2.7E-20 T 14-10-2018 IPR005119 LysR, substrate-binding MB46_16330 86cd7e51617166d51d7b1d63bc54647b 313 SUPERFAMILY SSF46785 1 105 7.97E-14 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_16330 86cd7e51617166d51d7b1d63bc54647b 313 SUPERFAMILY SSF53850 92 299 1.57E-22 T 14-10-2018 MB46_16330 86cd7e51617166d51d7b1d63bc54647b 313 Gene3D G3DSA:1.10.10.10 1 93 3.0E-14 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_16330 86cd7e51617166d51d7b1d63bc54647b 313 Gene3D G3DSA:3.40.190.10 167 269 3.6E-21 T 14-10-2018 MB46_16330 86cd7e51617166d51d7b1d63bc54647b 313 Gene3D G3DSA:3.40.190.10 137 278 3.6E-21 T 14-10-2018 MB46_16330 86cd7e51617166d51d7b1d63bc54647b 313 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 61 1.1E-12 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MB46_06460 67b388cf5ddb3d6df5c1a1462c94be80 510 PIRSF PIRSF002741 2 505 2.9E-78 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 MB46_06460 67b388cf5ddb3d6df5c1a1462c94be80 510 Gene3D G3DSA:3.10.105.10 269 481 3.3E-93 T 14-10-2018 MB46_06460 67b388cf5ddb3d6df5c1a1462c94be80 510 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 85 107 - T 14-10-2018 IPR023765 Solute-binding protein family 5, conserved site MB46_06460 67b388cf5ddb3d6df5c1a1462c94be80 510 Gene3D G3DSA:3.40.190.10 65 491 3.3E-93 T 14-10-2018 MB46_06460 67b388cf5ddb3d6df5c1a1462c94be80 510 SUPERFAMILY SSF53850 32 490 2.17E-96 T 14-10-2018 MB46_06460 67b388cf5ddb3d6df5c1a1462c94be80 510 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 80 414 6.0E-72 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain MB46_08565 e8b151fc215cfe8b70958d92894d3406 124 Pfam PF06103 Bacterial protein of unknown function (DUF948) 6 86 6.8E-21 T 14-10-2018 IPR009293 Uncharacterised protein family UPF0478 MB46_09085 a04f300710cd66084cb786b8668ec6a4 157 Gene3D G3DSA:3.40.1400.10 1 156 1.2E-52 T 14-10-2018 IPR036569 Sugar-phosphate isomerase, RpiB/LacA/LacB superfamily GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 MB46_09085 a04f300710cd66084cb786b8668ec6a4 157 Pfam PF02502 Ribose/Galactose Isomerase 3 146 7.8E-43 T 14-10-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 MB46_09085 a04f300710cd66084cb786b8668ec6a4 157 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 3 151 2.4E-48 T 14-10-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 MB46_09085 a04f300710cd66084cb786b8668ec6a4 157 PIRSF PIRSF005384 1 153 4.6E-46 T 14-10-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 MB46_09085 a04f300710cd66084cb786b8668ec6a4 157 SUPERFAMILY SSF89623 1 153 2.49E-48 T 14-10-2018 IPR036569 Sugar-phosphate isomerase, RpiB/LacA/LacB superfamily GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 MB46_09085 a04f300710cd66084cb786b8668ec6a4 157 TIGRFAM TIGR02133 RPI_actino: ribose 5-phosphate isomerase 1 152 2.1E-60 T 14-10-2018 IPR011860 Ribose 5-phosphate isomerase GO:0004751 MB46_17930 ad4a580c99590fb269ce93ff685d309b 103 SUPERFAMILY SSF46785 3 94 2.25E-23 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_17930 ad4a580c99590fb269ce93ff685d309b 103 Gene3D G3DSA:1.10.10.10 1 99 1.0E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_17930 ad4a580c99590fb269ce93ff685d309b 103 Pfam PF03551 Transcriptional regulator PadR-like family 13 83 4.8E-18 T 14-10-2018 IPR005149 Transcription regulator PadR, N-terminal MB46_01520 060c23916ebbb6fdc90f68a378a09dc2 281 SUPERFAMILY SSF161098 9 280 9.35E-74 T 14-10-2018 IPR035906 MetI-like superfamily MB46_01520 060c23916ebbb6fdc90f68a378a09dc2 281 Gene3D G3DSA:1.10.3720.10 2 268 3.4E-63 T 14-10-2018 IPR035906 MetI-like superfamily MB46_01520 060c23916ebbb6fdc90f68a378a09dc2 281 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 91 270 3.0E-21 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_11695 510a2b2b18ef1d155f2796682d681b56 320 Gene3D G3DSA:1.10.3720.10 76 293 1.9E-15 T 14-10-2018 IPR035906 MetI-like superfamily MB46_11695 510a2b2b18ef1d155f2796682d681b56 320 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 105 297 5.3E-24 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_11695 510a2b2b18ef1d155f2796682d681b56 320 SUPERFAMILY SSF161098 84 279 2.62E-17 T 14-10-2018 IPR035906 MetI-like superfamily MB46_08480 2cc0129ae22c5c73a3b08d1536c9bc84 393 SUPERFAMILY SSF52021 9 146 4.71E-55 T 14-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MB46_08480 2cc0129ae22c5c73a3b08d1536c9bc84 393 Gene3D G3DSA:3.40.50.880 159 384 7.7E-56 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like MB46_08480 2cc0129ae22c5c73a3b08d1536c9bc84 393 SMART SM01097 8 138 1.3E-86 T 14-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MB46_08480 2cc0129ae22c5c73a3b08d1536c9bc84 393 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 10 382 3.1E-136 T 14-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MB46_08480 2cc0129ae22c5c73a3b08d1536c9bc84 393 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 8 385 45.789 T 14-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MB46_08480 2cc0129ae22c5c73a3b08d1536c9bc84 393 Gene3D G3DSA:3.50.30.20 8 155 9.7E-58 T 14-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MB46_08480 2cc0129ae22c5c73a3b08d1536c9bc84 393 PRINTS PR00097 Anthranilate synthase component II signature 356 369 1.8E-5 T 14-10-2018 MB46_08480 2cc0129ae22c5c73a3b08d1536c9bc84 393 PRINTS PR00097 Anthranilate synthase component II signature 262 273 1.8E-5 T 14-10-2018 MB46_08480 2cc0129ae22c5c73a3b08d1536c9bc84 393 PRINTS PR00097 Anthranilate synthase component II signature 234 243 1.8E-5 T 14-10-2018 MB46_08480 2cc0129ae22c5c73a3b08d1536c9bc84 393 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 10 137 6.6E-52 T 14-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MB46_08480 2cc0129ae22c5c73a3b08d1536c9bc84 393 Pfam PF00117 Glutamine amidotransferase class-I 196 379 2.1E-37 T 14-10-2018 IPR017926 Glutamine amidotransferase MB46_08480 2cc0129ae22c5c73a3b08d1536c9bc84 393 SUPERFAMILY SSF52317 188 382 1.23E-49 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like MB46_08480 2cc0129ae22c5c73a3b08d1536c9bc84 393 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 279 296 1.9E-30 T 14-10-2018 MB46_08480 2cc0129ae22c5c73a3b08d1536c9bc84 393 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 231 245 1.9E-30 T 14-10-2018 MB46_08480 2cc0129ae22c5c73a3b08d1536c9bc84 393 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 262 278 1.9E-30 T 14-10-2018 MB46_08480 2cc0129ae22c5c73a3b08d1536c9bc84 393 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 192 206 1.9E-30 T 14-10-2018 MB46_08480 2cc0129ae22c5c73a3b08d1536c9bc84 393 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 304 315 1.9E-30 T 14-10-2018 MB46_08480 2cc0129ae22c5c73a3b08d1536c9bc84 393 PRINTS PR00096 Glutamine amidotransferase superfamily signature 234 243 7.9E-11 T 14-10-2018 MB46_08480 2cc0129ae22c5c73a3b08d1536c9bc84 393 PRINTS PR00096 Glutamine amidotransferase superfamily signature 356 369 7.9E-11 T 14-10-2018 MB46_08480 2cc0129ae22c5c73a3b08d1536c9bc84 393 PRINTS PR00096 Glutamine amidotransferase superfamily signature 262 273 7.9E-11 T 14-10-2018 MB46_13435 52f6d39b0b197e62e964a5a8427c0f07 216 Gene3D G3DSA:2.40.50.620 38 101 8.0E-19 T 14-10-2018 MB46_13435 52f6d39b0b197e62e964a5a8427c0f07 216 Pfam PF00297 Ribosomal protein L3 102 188 9.8E-18 T 14-10-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MB46_13435 52f6d39b0b197e62e964a5a8427c0f07 216 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 7 213 40.009 T 14-10-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_13435 52f6d39b0b197e62e964a5a8427c0f07 216 SUPERFAMILY SSF50447 6 214 1.24E-81 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily MB46_13435 52f6d39b0b197e62e964a5a8427c0f07 216 Gene3D G3DSA:2.40.30.10 126 216 5.1E-16 T 14-10-2018 MB46_13435 52f6d39b0b197e62e964a5a8427c0f07 216 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 9 210 8.6E-89 T 14-10-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_13435 52f6d39b0b197e62e964a5a8427c0f07 216 ProSitePatterns PS00474 Ribosomal protein L3 signature. 107 130 - T 14-10-2018 IPR019926 Ribosomal protein L3, conserved site MB46_00335 decdea5ab4955886f42043581b1b98aa 62 Pfam PF14013 MT0933-like antitoxin protein 8 57 1.5E-11 T 14-10-2018 IPR028037 Antitoxin Rv0909/MT0933 MB46_08600 9cab51972073285f1f2640f9608d34e3 327 Pfam PF01497 Periplasmic binding protein 57 300 2.5E-21 T 14-10-2018 IPR002491 ABC transporter periplasmic binding domain MB46_08600 9cab51972073285f1f2640f9608d34e3 327 Gene3D G3DSA:3.40.50.1980 159 327 3.2E-44 T 14-10-2018 MB46_08600 9cab51972073285f1f2640f9608d34e3 327 SUPERFAMILY SSF53807 37 322 3.92E-36 T 14-10-2018 MB46_08600 9cab51972073285f1f2640f9608d34e3 327 Gene3D G3DSA:3.40.50.1980 23 155 6.1E-44 T 14-10-2018 MB46_00825 7cec504d27fb204b531b38d5531ffc3b 304 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 4 159 9.3E-47 T 14-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 MB46_00825 7cec504d27fb204b531b38d5531ffc3b 304 Gene3D G3DSA:1.10.1040.10 166 295 5.8E-39 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MB46_00825 7cec504d27fb204b531b38d5531ffc3b 304 SUPERFAMILY SSF48179 166 293 6.8E-35 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MB46_00825 7cec504d27fb204b531b38d5531ffc3b 304 PIRSF PIRSF000103 1 299 1.8E-74 T 14-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 MB46_00825 7cec504d27fb204b531b38d5531ffc3b 304 Gene3D G3DSA:3.40.50.720 2 163 9.9E-51 T 14-10-2018 MB46_00825 7cec504d27fb204b531b38d5531ffc3b 304 TIGRFAM TIGR01692 HIBADH: 3-hydroxyisobutyrate dehydrogenase 6 291 7.2E-102 T 14-10-2018 IPR011548 3-hydroxyisobutyrate dehydrogenase GO:0008442|GO:0051287|GO:0055114 KEGG: 00280+1.1.1.31|Reactome: R-HSA-70895 MB46_00825 7cec504d27fb204b531b38d5531ffc3b 304 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 166 291 2.8E-31 T 14-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 MB46_00825 7cec504d27fb204b531b38d5531ffc3b 304 SUPERFAMILY SSF51735 3 162 1.71E-39 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_13920 498d77cb1a9808902a7534142627d021 1150 SUPERFAMILY SSF51730 136 472 6.28E-71 T 14-10-2018 IPR029041 FAD-linked oxidoreductase-like MB46_13920 498d77cb1a9808902a7534142627d021 1150 Gene3D G3DSA:3.40.605.10 516 941 3.1E-110 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 MB46_13920 498d77cb1a9808902a7534142627d021 1150 Pfam PF01619 Proline dehydrogenase 140 433 3.0E-61 T 14-10-2018 IPR002872 Proline dehydrogenase domain KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922|Reactome: R-HSA-70688 MB46_13920 498d77cb1a9808902a7534142627d021 1150 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 721 728 - T 14-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 MB46_13920 498d77cb1a9808902a7534142627d021 1150 SUPERFAMILY SSF53720 515 942 1.31E-99 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 MB46_13920 498d77cb1a9808902a7534142627d021 1150 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 749 760 - T 14-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 MB46_13920 498d77cb1a9808902a7534142627d021 1150 PIRSF PIRSF000197 19 1148 2.0E-263 T 14-10-2018 IPR025703 Bifunctional protein PutA GO:0003700|GO:0003842|GO:0004657|GO:0006355|GO:0010133 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 MB46_13920 498d77cb1a9808902a7534142627d021 1150 Pfam PF00171 Aldehyde dehydrogenase family 518 941 1.4E-103 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 MB46_13920 498d77cb1a9808902a7534142627d021 1150 Gene3D G3DSA:3.20.20.220 75 465 3.5E-103 T 14-10-2018 MB46_13920 498d77cb1a9808902a7534142627d021 1150 Gene3D G3DSA:3.40.309.10 725 916 3.1E-110 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 MB46_06165 82a081d841aadad09cb658b899661968 343 Gene3D G3DSA:3.90.180.10 5 332 5.0E-88 T 14-10-2018 MB46_06165 82a081d841aadad09cb658b899661968 343 Pfam PF00107 Zinc-binding dehydrogenase 177 305 1.3E-17 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 MB46_06165 82a081d841aadad09cb658b899661968 343 SUPERFAMILY SSF51735 147 310 3.18E-33 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_06165 82a081d841aadad09cb658b899661968 343 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 127 2.8E-24 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MB46_06165 82a081d841aadad09cb658b899661968 343 Gene3D G3DSA:3.40.50.720 157 305 5.0E-88 T 14-10-2018 MB46_06165 82a081d841aadad09cb658b899661968 343 SUPERFAMILY SSF50129 1 163 1.79E-47 T 14-10-2018 IPR011032 GroES-like superfamily MB46_06165 82a081d841aadad09cb658b899661968 343 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 58 72 - T 14-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 MB46_03840 a83e5424403990793d6cd6ad786bde36 439 Pfam PF03453 MoeA N-terminal region (domain I and II) 5 186 6.8E-39 T 14-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MB46_03840 a83e5424403990793d6cd6ad786bde36 439 Pfam PF03454 MoeA C-terminal region (domain IV) 367 439 1.4E-12 T 14-10-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MB46_03840 a83e5424403990793d6cd6ad786bde36 439 SMART SM00852 199 354 8.4E-26 T 14-10-2018 IPR001453 MoaB/Mog domain MB46_03840 a83e5424403990793d6cd6ad786bde36 439 SUPERFAMILY SSF53218 196 357 9.03E-29 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily MB46_03840 a83e5424403990793d6cd6ad786bde36 439 Pfam PF00994 Probable molybdopterin binding domain 201 353 1.4E-15 T 14-10-2018 IPR001453 MoaB/Mog domain MB46_03840 a83e5424403990793d6cd6ad786bde36 439 SUPERFAMILY SSF63882 33 194 1.96E-39 T 14-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MB46_03840 a83e5424403990793d6cd6ad786bde36 439 SUPERFAMILY SSF63867 362 439 1.09E-12 T 14-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MB46_03840 a83e5424403990793d6cd6ad786bde36 439 Gene3D G3DSA:2.170.190.11 59 160 1.1E-108 T 14-10-2018 MB46_03840 a83e5424403990793d6cd6ad786bde36 439 Gene3D G3DSA:3.90.105.10 35 193 1.1E-108 T 14-10-2018 MB46_03840 a83e5424403990793d6cd6ad786bde36 439 Gene3D G3DSA:3.40.980.10 194 362 1.1E-108 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily MB46_03840 a83e5424403990793d6cd6ad786bde36 439 Gene3D G3DSA:2.40.340.10 363 434 1.1E-108 T 14-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MB46_08085 bfbc716f5159d7b99f3e771c898e86f0 256 ProDom PD037701 MEMBRANE INTEGRAL TRANSMEMBRANE RV2219/MT2276 NARROWLY PROBABLE PRECURSOR SIGNAL MLCB22.21 36 250 3.0E-72 T 14-10-2018 MB46_08085 bfbc716f5159d7b99f3e771c898e86f0 256 Pfam PF13829 Domain of unknown function (DUF4191) 32 251 6.5E-79 T 14-10-2018 IPR025445 Protein of unknown function DUF4191 MB46_19860 376d2cf1bfd825339010731ca82e1401 1207 SUPERFAMILY SSF52540 464 674 4.36E-22 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_19860 376d2cf1bfd825339010731ca82e1401 1207 SMART SM00382 483 787 7.1E-6 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_19860 376d2cf1bfd825339010731ca82e1401 1207 Gene3D G3DSA:3.40.50.300 732 899 2.2E-5 T 14-10-2018 MB46_19860 376d2cf1bfd825339010731ca82e1401 1207 SUPERFAMILY SSF52540 651 898 4.99E-24 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_19860 376d2cf1bfd825339010731ca82e1401 1207 Pfam PF08751 TrwC relaxase 4 302 9.9E-63 T 14-10-2018 IPR014862 TrwC relaxase MB46_19860 376d2cf1bfd825339010731ca82e1401 1207 Pfam PF13604 AAA domain 568 724 1.2E-30 T 14-10-2018 MB46_19860 376d2cf1bfd825339010731ca82e1401 1207 Pfam PF13604 AAA domain 468 552 3.7E-22 T 14-10-2018 MB46_19860 376d2cf1bfd825339010731ca82e1401 1207 SUPERFAMILY SSF55464 3 314 4.17E-54 T 14-10-2018 MB46_10935 109001684e213f6740c7de2c2f87e4c8 329 PRINTS PR00958 Homoserine kinase signature 186 203 1.1E-37 T 14-10-2018 MB46_10935 109001684e213f6740c7de2c2f87e4c8 329 PRINTS PR00958 Homoserine kinase signature 27 42 1.1E-37 T 14-10-2018 MB46_10935 109001684e213f6740c7de2c2f87e4c8 329 PRINTS PR00958 Homoserine kinase signature 111 126 1.1E-37 T 14-10-2018 MB46_10935 109001684e213f6740c7de2c2f87e4c8 329 PRINTS PR00958 Homoserine kinase signature 147 160 1.1E-37 T 14-10-2018 MB46_10935 109001684e213f6740c7de2c2f87e4c8 329 PRINTS PR00958 Homoserine kinase signature 263 278 1.1E-37 T 14-10-2018 MB46_10935 109001684e213f6740c7de2c2f87e4c8 329 Pfam PF00288 GHMP kinases N terminal domain 98 159 6.3E-11 T 14-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 MB46_10935 109001684e213f6740c7de2c2f87e4c8 329 PIRSF PIRSF000676 17 326 1.1E-80 T 14-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 MB46_10935 109001684e213f6740c7de2c2f87e4c8 329 TIGRFAM TIGR00191 thrB: homoserine kinase 21 301 9.1E-66 T 14-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 MB46_10935 109001684e213f6740c7de2c2f87e4c8 329 SUPERFAMILY SSF55060 184 301 4.03E-28 T 14-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily MB46_10935 109001684e213f6740c7de2c2f87e4c8 329 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 104 115 - T 14-10-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 MB46_10935 109001684e213f6740c7de2c2f87e4c8 329 Gene3D G3DSA:3.30.230.10 22 176 1.8E-80 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MB46_10935 109001684e213f6740c7de2c2f87e4c8 329 SUPERFAMILY SSF54211 20 165 3.57E-26 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MB46_10935 109001684e213f6740c7de2c2f87e4c8 329 Pfam PF08544 GHMP kinases C terminal 231 296 6.5E-7 T 14-10-2018 IPR013750 GHMP kinase, C-terminal domain MB46_10935 109001684e213f6740c7de2c2f87e4c8 329 Gene3D G3DSA:3.30.70.890 177 286 1.8E-80 T 14-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily MB46_10935 109001684e213f6740c7de2c2f87e4c8 329 Hamap MF_00384 Homoserine kinase [thrB]. 22 324 29.294 T 14-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 MB46_00915 c23951b65b2e161acd95dd52020459a2 177 Pfam PF05154 TM2 domain 101 157 2.2E-16 T 14-10-2018 IPR007829 TM2 domain MB46_05780 d32e3cdc1c565f861b51fe5cf3433981 209 Pfam PF00583 Acetyltransferase (GNAT) family 38 137 2.3E-8 T 14-10-2018 IPR000182 GNAT domain MB46_05780 d32e3cdc1c565f861b51fe5cf3433981 209 Gene3D G3DSA:3.40.630.30 1 182 3.4E-15 T 14-10-2018 MB46_05780 d32e3cdc1c565f861b51fe5cf3433981 209 SUPERFAMILY SSF55729 3 141 1.13E-13 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase MB46_06545 d047548a3adb8c84a1e78b637c961414 502 Gene3D G3DSA:2.60.120.560 356 501 2.6E-40 T 14-10-2018 MB46_06545 d047548a3adb8c84a1e78b637c961414 502 SUPERFAMILY SSF49899 358 498 1.82E-28 T 14-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily MB46_06545 d047548a3adb8c84a1e78b637c961414 502 Pfam PF00251 Glycosyl hydrolases family 32 N-terminal domain 17 337 6.3E-90 T 14-10-2018 IPR013148 Glycosyl hydrolase family 32, N-terminal MB46_06545 d047548a3adb8c84a1e78b637c961414 502 Pfam PF08244 Glycosyl hydrolases family 32 C terminal 370 499 1.4E-32 T 14-10-2018 IPR013189 Glycosyl hydrolase family 32, C-terminal MB46_06545 d047548a3adb8c84a1e78b637c961414 502 Gene3D G3DSA:2.115.10.20 9 344 2.4E-116 T 14-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily MB46_06545 d047548a3adb8c84a1e78b637c961414 502 SUPERFAMILY SSF75005 11 341 1.1E-96 T 14-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily MB46_06545 d047548a3adb8c84a1e78b637c961414 502 SMART SM00640 17 465 1.4E-140 T 14-10-2018 IPR001362 Glycoside hydrolase, family 32 GO:0004553|GO:0005975 MB46_13390 53f8f4bc54ca48d0f3cca62d631ed546 98 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 20 95 24.021 T 14-10-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MB46_13390 53f8f4bc54ca48d0f3cca62d631ed546 98 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 25 91 7.0E-29 T 14-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MB46_13390 53f8f4bc54ca48d0f3cca62d631ed546 98 SUPERFAMILY SSF50249 20 97 2.27E-30 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold MB46_13390 53f8f4bc54ca48d0f3cca62d631ed546 98 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 20 91 9.4E-34 T 14-10-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MB46_13390 53f8f4bc54ca48d0f3cca62d631ed546 98 PRINTS PR00973 Ribosomal protein S17 family signature 81 88 3.5E-12 T 14-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MB46_13390 53f8f4bc54ca48d0f3cca62d631ed546 98 PRINTS PR00973 Ribosomal protein S17 family signature 39 62 3.5E-12 T 14-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MB46_13390 53f8f4bc54ca48d0f3cca62d631ed546 98 PRINTS PR00973 Ribosomal protein S17 family signature 71 81 3.5E-12 T 14-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MB46_13390 53f8f4bc54ca48d0f3cca62d631ed546 98 ProSitePatterns PS00056 Ribosomal protein S17 signature. 71 83 - T 14-10-2018 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MB46_13390 53f8f4bc54ca48d0f3cca62d631ed546 98 Pfam PF00366 Ribosomal protein S17 25 92 8.3E-31 T 14-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MB46_13390 53f8f4bc54ca48d0f3cca62d631ed546 98 Gene3D G3DSA:2.40.50.140 19 98 3.5E-33 T 14-10-2018 MB46_02700 dec41f1f1bc502d2705ecc7a95a8b774 1210 SMART SM00487 658 848 1.0E-33 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MB46_02700 dec41f1f1bc502d2705ecc7a95a8b774 1210 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 54 1158 27.531 T 14-10-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 MB46_02700 dec41f1f1bc502d2705ecc7a95a8b774 1210 SUPERFAMILY SSF52540 840 1047 1.97E-45 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_02700 dec41f1f1bc502d2705ecc7a95a8b774 1210 Gene3D G3DSA:3.40.50.300 526 1046 2.9E-226 T 14-10-2018 MB46_02700 dec41f1f1bc502d2705ecc7a95a8b774 1210 SUPERFAMILY SSF141259 519 601 7.45E-15 T 14-10-2018 IPR036101 CarD-like/TRCF domain superfamily MB46_02700 dec41f1f1bc502d2705ecc7a95a8b774 1210 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 173 1134 0.0 T 14-10-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 MB46_02700 dec41f1f1bc502d2705ecc7a95a8b774 1210 Pfam PF00271 Helicase conserved C-terminal domain 868 967 7.4E-15 T 14-10-2018 IPR001650 Helicase, C-terminal MB46_02700 dec41f1f1bc502d2705ecc7a95a8b774 1210 Gene3D G3DSA:3.30.2060.10 156 249 1.2E-55 T 14-10-2018 MB46_02700 dec41f1f1bc502d2705ecc7a95a8b774 1210 Gene3D G3DSA:3.90.1150.50 1057 1181 4.1E-24 T 14-10-2018 IPR037235 TRCF-like, C-terminal domain MB46_02700 dec41f1f1bc502d2705ecc7a95a8b774 1210 Gene3D G3DSA:3.40.50.300 600 839 2.9E-226 T 14-10-2018 MB46_02700 dec41f1f1bc502d2705ecc7a95a8b774 1210 Pfam PF02559 CarD-like/TRCF domain 527 633 9.6E-27 T 14-10-2018 IPR003711 CarD-like/TRCF domain MB46_02700 dec41f1f1bc502d2705ecc7a95a8b774 1210 Pfam PF00270 DEAD/DEAH box helicase 683 824 1.7E-17 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MB46_02700 dec41f1f1bc502d2705ecc7a95a8b774 1210 Pfam PF03461 TRCF domain 1062 1146 2.2E-22 T 14-10-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 MB46_02700 dec41f1f1bc502d2705ecc7a95a8b774 1210 SUPERFAMILY SSF52540 402 513 7.3E-15 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_02700 dec41f1f1bc502d2705ecc7a95a8b774 1210 Gene3D G3DSA:2.30.30.840 530 599 2.9E-226 T 14-10-2018 MB46_02700 dec41f1f1bc502d2705ecc7a95a8b774 1210 SUPERFAMILY SSF143517 1048 1205 8.5E-32 T 14-10-2018 IPR037235 TRCF-like, C-terminal domain MB46_02700 dec41f1f1bc502d2705ecc7a95a8b774 1210 SMART SM00490 884 968 1.8E-16 T 14-10-2018 IPR001650 Helicase, C-terminal MB46_02700 dec41f1f1bc502d2705ecc7a95a8b774 1210 SMART SM01058 526 634 3.4E-40 T 14-10-2018 IPR003711 CarD-like/TRCF domain MB46_02700 dec41f1f1bc502d2705ecc7a95a8b774 1210 SUPERFAMILY SSF52540 584 841 4.75E-61 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_02700 dec41f1f1bc502d2705ecc7a95a8b774 1210 Gene3D G3DSA:3.40.50.11180 63 333 1.2E-55 T 14-10-2018 MB46_02700 dec41f1f1bc502d2705ecc7a95a8b774 1210 SUPERFAMILY SSF52540 57 341 1.11E-63 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_02700 dec41f1f1bc502d2705ecc7a95a8b774 1210 SMART SM00982 1061 1158 2.7E-33 T 14-10-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 MB46_00060 2f60e8f0e126697c9911b76ab92041fa 548 SUPERFAMILY SSF51445 53 462 1.17E-73 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily MB46_00060 2f60e8f0e126697c9911b76ab92041fa 548 Gene3D G3DSA:3.20.20.80 52 455 1.5E-100 T 14-10-2018 MB46_00060 2f60e8f0e126697c9911b76ab92041fa 548 SMART SM00642 64 453 1.2E-57 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MB46_00060 2f60e8f0e126697c9911b76ab92041fa 548 Pfam PF00128 Alpha amylase, catalytic domain 108 420 3.3E-43 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MB46_02500 bb89480675462f9835f5e99e9c6e68ef 646 SUPERFAMILY SSF88713 47 166 1.06E-22 T 14-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 MB46_02500 bb89480675462f9835f5e99e9c6e68ef 646 Pfam PF00395 S-layer homology domain 590 633 1.7E-8 T 14-10-2018 IPR001119 S-layer homology domain MB46_02500 bb89480675462f9835f5e99e9c6e68ef 646 Pfam PF00395 S-layer homology domain 530 572 3.4E-12 T 14-10-2018 IPR001119 S-layer homology domain MB46_02500 bb89480675462f9835f5e99e9c6e68ef 646 Pfam PF00395 S-layer homology domain 467 510 6.4E-9 T 14-10-2018 IPR001119 S-layer homology domain MB46_02500 bb89480675462f9835f5e99e9c6e68ef 646 Pfam PF01522 Polysaccharide deacetylase 47 165 3.9E-14 T 14-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 MB46_02500 bb89480675462f9835f5e99e9c6e68ef 646 Gene3D G3DSA:2.60.120.260 298 461 1.2E-8 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily MB46_02500 bb89480675462f9835f5e99e9c6e68ef 646 Gene3D G3DSA:3.20.20.370 37 182 7.7E-23 T 14-10-2018 MB46_08025 e4f5b060f5ea657a1fec2c6c151905ed 405 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 16 405 31.031 T 14-10-2018 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 MB46_08025 e4f5b060f5ea657a1fec2c6c151905ed 405 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 196 209 - T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MB46_08025 e4f5b060f5ea657a1fec2c6c151905ed 405 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 168 393 2.8E-36 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 MB46_08025 e4f5b060f5ea657a1fec2c6c151905ed 405 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 365 391 - T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MB46_08025 e4f5b060f5ea657a1fec2c6c151905ed 405 Pfam PF04539 Sigma-70 region 3 251 327 2.7E-29 T 14-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 MB46_08025 e4f5b060f5ea657a1fec2c6c151905ed 405 Pfam PF04545 Sigma-70, region 4 340 393 3.1E-18 T 14-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 MB46_08025 e4f5b060f5ea657a1fec2c6c151905ed 405 PRINTS PR00046 Major sigma-70 factor signature 220 228 2.3E-29 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MB46_08025 e4f5b060f5ea657a1fec2c6c151905ed 405 PRINTS PR00046 Major sigma-70 factor signature 344 356 2.3E-29 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MB46_08025 e4f5b060f5ea657a1fec2c6c151905ed 405 PRINTS PR00046 Major sigma-70 factor signature 196 209 2.3E-29 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MB46_08025 e4f5b060f5ea657a1fec2c6c151905ed 405 PRINTS PR00046 Major sigma-70 factor signature 380 391 2.3E-29 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MB46_08025 e4f5b060f5ea657a1fec2c6c151905ed 405 PRINTS PR00046 Major sigma-70 factor signature 365 380 2.3E-29 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MB46_08025 e4f5b060f5ea657a1fec2c6c151905ed 405 Pfam PF00140 Sigma-70 factor, region 1.2 106 139 2.0E-13 T 14-10-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MB46_08025 e4f5b060f5ea657a1fec2c6c151905ed 405 Gene3D G3DSA:1.10.10.10 245 320 4.1E-30 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_08025 e4f5b060f5ea657a1fec2c6c151905ed 405 SUPERFAMILY SSF88659 245 318 1.79E-21 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like MB46_08025 e4f5b060f5ea657a1fec2c6c151905ed 405 SUPERFAMILY SSF88659 303 404 1.77E-27 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like MB46_08025 e4f5b060f5ea657a1fec2c6c151905ed 405 Gene3D G3DSA:1.10.601.10 143 244 6.7E-51 T 14-10-2018 MB46_08025 e4f5b060f5ea657a1fec2c6c151905ed 405 Gene3D G3DSA:1.10.601.10 104 142 1.0E-7 T 14-10-2018 MB46_08025 e4f5b060f5ea657a1fec2c6c151905ed 405 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 168 404 5.3E-113 T 14-10-2018 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 MB46_08025 e4f5b060f5ea657a1fec2c6c151905ed 405 Pfam PF04542 Sigma-70 region 2 172 241 1.9E-22 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 MB46_08025 e4f5b060f5ea657a1fec2c6c151905ed 405 Gene3D G3DSA:1.10.10.10 322 405 9.5E-32 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_08025 e4f5b060f5ea657a1fec2c6c151905ed 405 SUPERFAMILY SSF88946 106 242 2.35E-51 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 MB46_01435 1ee845507b320946e7141b19b588140d 489 SUPERFAMILY SSF142764 33 485 2.09E-67 T 14-10-2018 MB46_01435 1ee845507b320946e7141b19b588140d 489 Pfam PF17042 Putative nucleotide-binding of sugar-metabolising enzyme 315 478 1.8E-35 T 14-10-2018 IPR031475 Four-carbon acid sugar kinase, C-terminal domain MB46_01435 1ee845507b320946e7141b19b588140d 489 Pfam PF07005 Putative sugar-binding N-terminal domain 33 284 9.6E-56 T 14-10-2018 IPR010737 Four-carbon acid sugar kinase, N-terminal domain MB46_01435 1ee845507b320946e7141b19b588140d 489 Gene3D G3DSA:3.40.980.20 304 487 5.1E-10 T 14-10-2018 MB46_01435 1ee845507b320946e7141b19b588140d 489 Gene3D G3DSA:3.40.50.10840 32 272 1.9E-26 T 14-10-2018 IPR037051 Four-carbon acid sugar kinase, N-terminal domain superfamily MB46_15500 6902bf855ed28e02d46972e7576a1561 377 SUPERFAMILY SSF82829 236 355 3.14E-10 T 14-10-2018 MB46_15500 6902bf855ed28e02d46972e7576a1561 377 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 49 228 8.0E-41 T 14-10-2018 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 MB46_15500 6902bf855ed28e02d46972e7576a1561 377 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 28 353 19.982 T 14-10-2018 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 MB46_15500 6902bf855ed28e02d46972e7576a1561 377 Pfam PF09179 TilS substrate binding domain 297 359 9.3E-5 T 14-10-2018 IPR015262 tRNA(Ile)-lysidine synthase , substrate-binding domain GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 MB46_15500 6902bf855ed28e02d46972e7576a1561 377 SUPERFAMILY SSF52402 40 259 1.18E-47 T 14-10-2018 MB46_15500 6902bf855ed28e02d46972e7576a1561 377 Gene3D G3DSA:3.40.50.620 38 259 5.0E-61 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MB46_15500 6902bf855ed28e02d46972e7576a1561 377 Pfam PF01171 PP-loop family 49 225 6.7E-36 T 14-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 MB46_02850 1922c3fd2f9e82871f809573390693ad 274 TIGRFAM TIGR02964 xanthine_xdhC: xanthine dehydrogenase accessory protein XdhC 18 258 3.9E-70 T 14-10-2018 IPR014308 Xanthine dehydrogenase accessory protein XdhC MB46_02850 1922c3fd2f9e82871f809573390693ad 274 SUPERFAMILY SSF51735 102 150 9.5E-6 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_02850 1922c3fd2f9e82871f809573390693ad 274 Pfam PF02625 XdhC and CoxI family 11 71 1.4E-16 T 14-10-2018 IPR003777 XdhC- CoxI MB46_02850 1922c3fd2f9e82871f809573390693ad 274 Pfam PF13478 XdhC Rossmann domain 109 257 5.9E-33 T 14-10-2018 IPR027051 XdhC Rossmann domain MB46_02850 1922c3fd2f9e82871f809573390693ad 274 Gene3D G3DSA:3.40.50.720 108 261 2.2E-30 T 14-10-2018 MB46_01685 c3ca58cbd8fe49caca79c6bccdfa7788 555 PIRSF PIRSF000414 6 555 6.1E-192 T 14-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MB46_01685 c3ca58cbd8fe49caca79c6bccdfa7788 555 SMART SM00798 142 466 3.9E-173 T 14-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MB46_01685 c3ca58cbd8fe49caca79c6bccdfa7788 555 SUPERFAMILY SSF52335 11 199 5.04E-62 T 14-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily MB46_01685 c3ca58cbd8fe49caca79c6bccdfa7788 555 SUPERFAMILY SSF53927 222 555 1.7E-114 T 14-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 MB46_01685 c3ca58cbd8fe49caca79c6bccdfa7788 555 Gene3D G3DSA:3.40.140.20 219 375 4.9E-55 T 14-10-2018 IPR024051 AICAR transformylase, duplicated domain superfamily KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MB46_01685 c3ca58cbd8fe49caca79c6bccdfa7788 555 Gene3D G3DSA:3.40.140.20 378 545 4.0E-51 T 14-10-2018 IPR024051 AICAR transformylase, duplicated domain superfamily KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MB46_01685 c3ca58cbd8fe49caca79c6bccdfa7788 555 Gene3D G3DSA:3.40.50.1380 3 204 4.2E-83 T 14-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily MB46_01685 c3ca58cbd8fe49caca79c6bccdfa7788 555 Pfam PF02142 MGS-like domain 23 136 5.5E-22 T 14-10-2018 IPR011607 Methylglyoxal synthase-like domain MB46_01685 c3ca58cbd8fe49caca79c6bccdfa7788 555 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 11 555 41.65 T 14-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MB46_01685 c3ca58cbd8fe49caca79c6bccdfa7788 555 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 12 555 1.3E-164 T 14-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MB46_01685 c3ca58cbd8fe49caca79c6bccdfa7788 555 Pfam PF01808 AICARFT/IMPCHase bienzyme 142 465 4.8E-109 T 14-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MB46_01685 c3ca58cbd8fe49caca79c6bccdfa7788 555 SMART SM00851 23 137 2.2E-46 T 14-10-2018 IPR011607 Methylglyoxal synthase-like domain MB46_00290 b9a7ba9d20c2e566569938e101b079f9 642 TIGRFAM TIGR04377 myo_inos_iolD: 3,5/4-trihydroxycyclohexa-1,2-dione hydrolase 1 639 6.1E-252 T 14-10-2018 IPR030817 3,5/4-Trihydroxycyclohexa-1,2-dione hydrolase GO:0016823|GO:0019310|GO:0030976 KEGG: 00562+3.7.1.22 MB46_00290 b9a7ba9d20c2e566569938e101b079f9 642 Gene3D G3DSA:3.40.50.1220 217 394 4.1E-39 T 14-10-2018 MB46_00290 b9a7ba9d20c2e566569938e101b079f9 642 Gene3D G3DSA:3.40.50.970 1 206 3.6E-28 T 14-10-2018 MB46_00290 b9a7ba9d20c2e566569938e101b079f9 642 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 222 357 2.2E-35 T 14-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 MB46_00290 b9a7ba9d20c2e566569938e101b079f9 642 SUPERFAMILY SSF52518 1 214 1.39E-25 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold MB46_00290 b9a7ba9d20c2e566569938e101b079f9 642 SUPERFAMILY SSF52467 188 367 9.05E-44 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily MB46_00290 b9a7ba9d20c2e566569938e101b079f9 642 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 1 201 4.5E-31 T 14-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 MB46_00290 b9a7ba9d20c2e566569938e101b079f9 642 SUPERFAMILY SSF52518 401 627 1.29E-42 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold MB46_00290 b9a7ba9d20c2e566569938e101b079f9 642 Gene3D G3DSA:3.40.50.970 397 605 4.5E-37 T 14-10-2018 MB46_00290 b9a7ba9d20c2e566569938e101b079f9 642 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 420 595 2.3E-33 T 14-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 MB46_17540 acbdfa2738b6566923b3e7b462bbdc47 317 SUPERFAMILY SSF160964 33 76 6.8E-6 T 14-10-2018 MB46_17540 acbdfa2738b6566923b3e7b462bbdc47 317 SUPERFAMILY SSF161098 73 301 7.85E-53 T 14-10-2018 IPR035906 MetI-like superfamily MB46_17540 acbdfa2738b6566923b3e7b462bbdc47 317 Gene3D G3DSA:1.10.3720.10 69 311 7.7E-65 T 14-10-2018 IPR035906 MetI-like superfamily MB46_17540 acbdfa2738b6566923b3e7b462bbdc47 317 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 107 303 1.3E-11 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_09490 cf0ceec28a8358f0150b1d18a82d7803 419 Gene3D G3DSA:3.40.47.10 1 254 3.5E-77 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 MB46_09490 cf0ceec28a8358f0150b1d18a82d7803 419 SMART SM00825 Beta-ketoacyl synthase 5 414 7.4E-13 T 14-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain MB46_09490 cf0ceec28a8358f0150b1d18a82d7803 419 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 3 410 1.8E-149 T 14-10-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 MB46_09490 cf0ceec28a8358f0150b1d18a82d7803 419 PIRSF PIRSF000447 1 413 1.1E-142 T 14-10-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 MB46_09490 cf0ceec28a8358f0150b1d18a82d7803 419 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 253 367 5.8E-31 T 14-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal MB46_09490 cf0ceec28a8358f0150b1d18a82d7803 419 SUPERFAMILY SSF53901 3 250 6.01E-67 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 MB46_09490 cf0ceec28a8358f0150b1d18a82d7803 419 Gene3D G3DSA:3.40.47.10 255 401 2.3E-44 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 MB46_09490 cf0ceec28a8358f0150b1d18a82d7803 419 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3 245 1.6E-55 T 14-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal MB46_09490 cf0ceec28a8358f0150b1d18a82d7803 419 SUPERFAMILY SSF53901 212 411 3.74E-62 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 MB46_01495 473d7634acd8db9bc71a8f410230b4c7 489 SUPERFAMILY SSF100950 1 213 3.5E-66 T 14-10-2018 IPR037171 NagB/RpiA transferase-like MB46_01495 473d7634acd8db9bc71a8f410230b4c7 489 Gene3D G3DSA:3.40.1080.10 1 161 3.5E-11 T 14-10-2018 MB46_01495 473d7634acd8db9bc71a8f410230b4c7 489 Pfam PF02550 Acetyl-CoA hydrolase/transferase N-terminal domain 2 207 1.2E-27 T 14-10-2018 IPR003702 Acetyl-CoA hydrolase/transferase GO:0003824|GO:0006084 MB46_01495 473d7634acd8db9bc71a8f410230b4c7 489 Gene3D G3DSA:3.40.1080.20 328 469 7.2E-34 T 14-10-2018 IPR038460 Acetyl-CoA hydrolase/transferase, C-terminal domain superfamily MB46_01495 473d7634acd8db9bc71a8f410230b4c7 489 TIGRFAM TIGR03458 YgfH_subfam: succinate CoA transferase 1 487 1.4E-233 T 14-10-2018 IPR017821 Succinate CoA transferase GO:0006084|GO:0016740 MB46_01495 473d7634acd8db9bc71a8f410230b4c7 489 Gene3D G3DSA:3.30.750.70 215 303 3.0E-6 T 14-10-2018 MB46_01495 473d7634acd8db9bc71a8f410230b4c7 489 Pfam PF13336 Acetyl-CoA hydrolase/transferase C-terminal domain 309 454 6.9E-37 T 14-10-2018 IPR026888 Acetyl-CoA hydrolase/transferase C-terminal domain MB46_01495 473d7634acd8db9bc71a8f410230b4c7 489 SUPERFAMILY SSF100950 217 488 6.98E-76 T 14-10-2018 IPR037171 NagB/RpiA transferase-like MB46_12780 41836b4a11f7c78f819120344bca0491 646 Gene3D G3DSA:3.40.710.10 337 646 7.6E-64 T 14-10-2018 MB46_12780 41836b4a11f7c78f819120344bca0491 646 SUPERFAMILY SSF56601 276 644 1.09E-56 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like MB46_12780 41836b4a11f7c78f819120344bca0491 646 Pfam PF00905 Penicillin binding protein transpeptidase domain 365 638 2.9E-40 T 14-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 MB46_12780 41836b4a11f7c78f819120344bca0491 646 Gene3D G3DSA:3.90.1310.30 137 315 1.5E-13 T 14-10-2018 MB46_12780 41836b4a11f7c78f819120344bca0491 646 SUPERFAMILY SSF56519 136 302 3.27E-17 T 14-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 MB46_12780 41836b4a11f7c78f819120344bca0491 646 Pfam PF03717 Penicillin-binding Protein dimerisation domain 142 301 1.5E-14 T 14-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 MB46_12780 41836b4a11f7c78f819120344bca0491 646 ProSitePatterns PS00337 Beta-lactamase class-D active site. 398 408 - T 14-10-2018 IPR002137 Beta-lactamase, class-D active site GO:0008800|GO:0017001 KEGG: 00311+3.5.2.6 MB46_12780 41836b4a11f7c78f819120344bca0491 646 Pfam PF05223 NTF2-like N-terminal transpeptidase domain 55 133 6.8E-7 T 14-10-2018 IPR007887 NTF2-like N-terminal transpeptidase GO:0046677 MB46_15895 b8c30160cf353a8813e220720e3c7fea 407 Gene3D G3DSA:3.30.565.10 278 402 1.5E-24 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MB46_15895 b8c30160cf353a8813e220720e3c7fea 407 Pfam PF07730 Histidine kinase 203 268 4.0E-20 T 14-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 MB46_15895 b8c30160cf353a8813e220720e3c7fea 407 SUPERFAMILY SSF55874 289 400 3.01E-11 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MB46_03565 ab1c5cc7080d4f16f26a19ab69b31f2f 385 TIGRFAM TIGR03181 PDH_E1_alph_x: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 16 358 1.4E-130 T 14-10-2018 IPR017596 Pyruvate dehydrogenase E1 component subunit alpha/BCKADH E1-alpha KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 MB46_03565 ab1c5cc7080d4f16f26a19ab69b31f2f 385 SUPERFAMILY SSF52518 10 360 8.18E-93 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold MB46_03565 ab1c5cc7080d4f16f26a19ab69b31f2f 385 Pfam PF00676 Dehydrogenase E1 component 51 319 1.1E-73 T 14-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 MB46_03565 ab1c5cc7080d4f16f26a19ab69b31f2f 385 Gene3D G3DSA:3.40.50.970 2 358 2.7E-109 T 14-10-2018 MB46_17120 4bfbdd8f73b72ccf1d74aac86db96508 996 Pfam PF01074 Glycosyl hydrolases family 38 N-terminal domain 255 505 3.4E-84 T 14-10-2018 IPR000602 Glycoside hydrolase family 38, N-terminal domain GO:0004559|GO:0006013 MB46_17120 4bfbdd8f73b72ccf1d74aac86db96508 996 Gene3D G3DSA:1.20.1270.50 522 618 1.9E-22 T 14-10-2018 IPR037094 Glycoside hydrolase family 38, central domain superfamily GO:0004559|GO:0006013 MB46_17120 4bfbdd8f73b72ccf1d74aac86db96508 996 SUPERFAMILY SSF74650 657 993 4.71E-55 T 14-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 MB46_17120 4bfbdd8f73b72ccf1d74aac86db96508 996 Gene3D G3DSA:3.20.110.10 248 519 3.0E-55 T 14-10-2018 IPR027291 Glycoside hydrolase 38, N-terminal domain superfamily MB46_17120 4bfbdd8f73b72ccf1d74aac86db96508 996 Pfam PF07748 Glycosyl hydrolases family 38 C-terminal domain 654 993 3.2E-52 T 14-10-2018 IPR011682 Glycosyl hydrolase family 38, C-terminal GO:0004559|GO:0006013 MB46_17120 4bfbdd8f73b72ccf1d74aac86db96508 996 SMART SM00872 519 597 2.9E-28 T 14-10-2018 IPR015341 Glycoside hydrolase family 38, central domain GO:0004559|GO:0006013 MB46_17120 4bfbdd8f73b72ccf1d74aac86db96508 996 SUPERFAMILY SSF88713 249 517 8.01E-77 T 14-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 MB46_17120 4bfbdd8f73b72ccf1d74aac86db96508 996 Gene3D G3DSA:2.70.98.30 725 882 3.1E-12 T 14-10-2018 MB46_17120 4bfbdd8f73b72ccf1d74aac86db96508 996 SUPERFAMILY SSF88688 518 622 7.85E-23 T 14-10-2018 IPR028995 Glycoside hydrolase families 57/38, central domain superfamily MB46_17120 4bfbdd8f73b72ccf1d74aac86db96508 996 Pfam PF09261 Alpha mannosidase middle domain 519 594 5.8E-21 T 14-10-2018 IPR015341 Glycoside hydrolase family 38, central domain GO:0004559|GO:0006013 MB46_15610 46c69ed3e66e2135fd19d03dfcb11376 547 Gene3D G3DSA:3.30.310.50 446 547 1.6E-34 T 14-10-2018 MB46_15610 46c69ed3e66e2135fd19d03dfcb11376 547 Gene3D G3DSA:3.40.120.10 220 320 3.3E-41 T 14-10-2018 MB46_15610 46c69ed3e66e2135fd19d03dfcb11376 547 Gene3D G3DSA:3.40.120.10 11 217 9.3E-71 T 14-10-2018 MB46_15610 46c69ed3e66e2135fd19d03dfcb11376 547 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 139 148 - T 14-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MB46_15610 46c69ed3e66e2135fd19d03dfcb11376 547 SUPERFAMILY SSF53738 208 319 1.53E-7 T 14-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MB46_15610 46c69ed3e66e2135fd19d03dfcb11376 547 TIGRFAM TIGR01132 pgm: phosphoglucomutase, alpha-D-glucose phosphate-specific 2 546 1.5E-281 T 14-10-2018 IPR005852 Phosphoglucomutase, alpha-D-glucose specific GO:0004614|GO:0005975 KEGG: 00010+5.4.2.2|KEGG: 00030+5.4.2.2|KEGG: 00052+5.4.2.2|KEGG: 00230+5.4.2.2|KEGG: 00500+5.4.2.2|KEGG: 00520+5.4.2.2|KEGG: 00521+5.4.2.2|MetaCyc: PWY-2723|MetaCyc: PWY-3801|MetaCyc: PWY-5384|MetaCyc: PWY-5661|MetaCyc: PWY-5940|MetaCyc: PWY-5941|MetaCyc: PWY-622|MetaCyc: PWY-6317|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-6981|MetaCyc: PWY-7238|MetaCyc: PWY-7343|MetaCyc: PWY-7900|MetaCyc: PWY-7902 MB46_15610 46c69ed3e66e2135fd19d03dfcb11376 547 SUPERFAMILY SSF53738 308 450 1.18E-32 T 14-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MB46_15610 46c69ed3e66e2135fd19d03dfcb11376 547 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 38 180 2.5E-36 T 14-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MB46_15610 46c69ed3e66e2135fd19d03dfcb11376 547 SUPERFAMILY SSF53738 24 234 1.15E-48 T 14-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MB46_15610 46c69ed3e66e2135fd19d03dfcb11376 547 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 489 541 4.3E-9 T 14-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MB46_15610 46c69ed3e66e2135fd19d03dfcb11376 547 Gene3D G3DSA:3.40.120.10 321 445 2.8E-34 T 14-10-2018 MB46_15610 46c69ed3e66e2135fd19d03dfcb11376 547 SUPERFAMILY SSF55957 436 546 2.38E-20 T 14-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MB46_15610 46c69ed3e66e2135fd19d03dfcb11376 547 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 323 442 1.0E-27 T 14-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MB46_15610 46c69ed3e66e2135fd19d03dfcb11376 547 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 209 319 3.0E-12 T 14-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MB46_02980 b97f094d1c749c6a7186ed4671064b09 256 SUPERFAMILY SSF53067 10 256 2.43E-36 T 14-10-2018 MB46_02980 b97f094d1c749c6a7186ed4671064b09 256 Gene3D G3DSA:3.30.420.40 3 118 4.7E-24 T 14-10-2018 MB46_02980 b97f094d1c749c6a7186ed4671064b09 256 Pfam PF00480 ROK family 11 172 1.3E-17 T 14-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 MB46_02980 b97f094d1c749c6a7186ed4671064b09 256 Gene3D G3DSA:3.30.420.40 119 256 5.6E-39 T 14-10-2018 MB46_01450 307e5bd7e54db5384a372ac2dd732edd 608 Pfam PF01844 HNH endonuclease 431 471 2.9E-5 T 14-10-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 MB46_01450 307e5bd7e54db5384a372ac2dd732edd 608 Gene3D G3DSA:3.30.40.60 399 495 4.1E-5 T 14-10-2018 MB46_01450 307e5bd7e54db5384a372ac2dd732edd 608 SMART SM00507 415 467 3.9E-7 T 14-10-2018 IPR003615 HNH nuclease MB46_01450 307e5bd7e54db5384a372ac2dd732edd 608 Pfam PF02720 Domain of unknown function (DUF222) 41 224 1.4E-20 T 14-10-2018 IPR003870 Domain of unknown function DUF222 MB46_00740 8ae37088ec0160f8743783f5e949281b 323 SUPERFAMILY SSF161098 87 265 1.44E-15 T 14-10-2018 IPR035906 MetI-like superfamily MB46_00740 8ae37088ec0160f8743783f5e949281b 323 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 111 295 5.9E-19 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_00740 8ae37088ec0160f8743783f5e949281b 323 Gene3D G3DSA:1.10.3720.10 77 295 6.7E-12 T 14-10-2018 IPR035906 MetI-like superfamily MB46_02820 9cda0b090db1d500eafea6f0bd294344 336 Gene3D G3DSA:3.40.50.720 148 285 2.1E-134 T 14-10-2018 MB46_02820 9cda0b090db1d500eafea6f0bd294344 336 Gene3D G3DSA:3.90.180.10 5 326 2.1E-134 T 14-10-2018 MB46_02820 9cda0b090db1d500eafea6f0bd294344 336 SUPERFAMILY SSF50129 1 180 2.74E-54 T 14-10-2018 IPR011032 GroES-like superfamily MB46_02820 9cda0b090db1d500eafea6f0bd294344 336 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 60 74 - T 14-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 MB46_02820 9cda0b090db1d500eafea6f0bd294344 336 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 130 3.8E-31 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MB46_02820 9cda0b090db1d500eafea6f0bd294344 336 SUPERFAMILY SSF51735 139 304 1.2E-45 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_02820 9cda0b090db1d500eafea6f0bd294344 336 SMART SM00829 10 334 1.4E-7 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MB46_02820 9cda0b090db1d500eafea6f0bd294344 336 Pfam PF00107 Zinc-binding dehydrogenase 175 299 1.8E-31 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 MB46_11440 aa331839dc446b6f590294a483bde528 362 SUPERFAMILY SSF51735 9 357 1.85E-71 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_11440 aa331839dc446b6f590294a483bde528 362 Pfam PF01370 NAD dependent epimerase/dehydratase family 12 271 2.4E-41 T 14-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 MB46_11440 aa331839dc446b6f590294a483bde528 362 Gene3D G3DSA:3.40.50.720 11 357 2.5E-74 T 14-10-2018 MB46_06525 4e3e7103664fd22d91743bea47ee7c92 568 Gene3D G3DSA:3.20.20.140 58 513 1.5E-114 T 14-10-2018 MB46_06525 4e3e7103664fd22d91743bea47ee7c92 568 Pfam PF07969 Amidohydrolase family 47 550 1.2E-76 T 14-10-2018 IPR013108 Amidohydrolase 3 MB46_06525 4e3e7103664fd22d91743bea47ee7c92 568 Gene3D G3DSA:2.30.40.10 9 530 1.5E-114 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 MB46_06525 4e3e7103664fd22d91743bea47ee7c92 568 SUPERFAMILY SSF51338 2 552 4.94E-17 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 MB46_06525 4e3e7103664fd22d91743bea47ee7c92 568 Gene3D G3DSA:3.10.310.70 76 199 1.5E-114 T 14-10-2018 MB46_06525 4e3e7103664fd22d91743bea47ee7c92 568 SUPERFAMILY SSF51556 57 514 7.21E-31 T 14-10-2018 IPR032466 Metal-dependent hydrolase MB46_14970 cdae223cf16a78ff274cf4ef04bd8e37 409 Pfam PF13378 Enolase C-terminal domain-like 200 384 6.8E-42 T 14-10-2018 IPR029065 Enolase C-terminal domain-like MB46_14970 cdae223cf16a78ff274cf4ef04bd8e37 409 Gene3D G3DSA:3.20.20.120 105 374 1.9E-161 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily MB46_14970 cdae223cf16a78ff274cf4ef04bd8e37 409 Gene3D G3DSA:3.30.390.10 6 406 1.9E-161 T 14-10-2018 IPR029017 Enolase-like, N-terminal MB46_14970 cdae223cf16a78ff274cf4ef04bd8e37 409 SMART SM00922 129 264 5.6E-18 T 14-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal MB46_14970 cdae223cf16a78ff274cf4ef04bd8e37 409 SUPERFAMILY SSF51604 98 393 1.05E-71 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily MB46_14970 cdae223cf16a78ff274cf4ef04bd8e37 409 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 85 110 - T 14-10-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 MB46_14970 cdae223cf16a78ff274cf4ef04bd8e37 409 SUPERFAMILY SSF54826 2 112 4.5E-34 T 14-10-2018 MB46_14970 cdae223cf16a78ff274cf4ef04bd8e37 409 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 11 110 4.7E-33 T 14-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain MB46_02305 6b5e256d0050efc6fb950e5827d5f996 416 Gene3D G3DSA:2.40.440.10 260 404 9.3E-74 T 14-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like MB46_02305 6b5e256d0050efc6fb950e5827d5f996 416 Pfam PF03734 L,D-transpeptidase catalytic domain 274 389 1.9E-10 T 14-10-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 MB46_02305 6b5e256d0050efc6fb950e5827d5f996 416 SUPERFAMILY SSF141523 261 389 1.02E-18 T 14-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like MB46_02305 6b5e256d0050efc6fb950e5827d5f996 416 Gene3D G3DSA:2.60.40.3780 62 158 7.3E-14 T 14-10-2018 MB46_02305 6b5e256d0050efc6fb950e5827d5f996 416 Gene3D G3DSA:2.60.40.3710 168 415 9.3E-74 T 14-10-2018 MB46_18065 bc72f139f8dfeafdbb1d00e6b0b2c237 306 SUPERFAMILY SSF56112 3 274 3.32E-16 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily MB46_18065 bc72f139f8dfeafdbb1d00e6b0b2c237 306 Pfam PF01636 Phosphotransferase enzyme family 24 212 5.3E-6 T 14-10-2018 IPR002575 Aminoglycoside phosphotransferase MB46_18365 be584b57073d8089ff4677d285381d51 449 TIGRFAM TIGR00430 Q_tRNA_tgt: tRNA-guanine transglycosylase 60 445 2.3E-124 T 14-10-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 MB46_18365 be584b57073d8089ff4677d285381d51 449 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 59 445 1.0E-121 T 14-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 MB46_18365 be584b57073d8089ff4677d285381d51 449 SUPERFAMILY SSF51713 58 445 3.14E-127 T 14-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 MB46_18365 be584b57073d8089ff4677d285381d51 449 Gene3D G3DSA:3.20.20.105 44 449 4.4E-143 T 14-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 MB46_18365 be584b57073d8089ff4677d285381d51 449 Pfam PF01702 Queuine tRNA-ribosyltransferase 204 440 9.6E-77 T 14-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 MB46_18365 be584b57073d8089ff4677d285381d51 449 Hamap MF_00168 Queuine tRNA-ribosyltransferase [tgt]. 32 444 44.967 T 14-10-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 MB46_14945 021643f147ca83374ffb4043b4d424ab 205 Pfam PF00588 SpoU rRNA Methylase family 56 192 5.5E-26 T 14-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 MB46_14945 021643f147ca83374ffb4043b4d424ab 205 SUPERFAMILY SSF75217 40 202 5.43E-39 T 14-10-2018 IPR029028 Alpha/beta knot methyltransferases MB46_14945 021643f147ca83374ffb4043b4d424ab 205 Gene3D G3DSA:3.40.1280.10 38 204 3.5E-34 T 14-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal MB46_18595 87942fab9ce605e752f49e2a68e3e94b 221 Gene3D G3DSA:3.40.630.30 4 218 2.7E-48 T 14-10-2018 MB46_18595 87942fab9ce605e752f49e2a68e3e94b 221 Pfam PF13302 Acetyltransferase (GNAT) domain 19 167 2.0E-13 T 14-10-2018 IPR000182 GNAT domain MB46_18595 87942fab9ce605e752f49e2a68e3e94b 221 SUPERFAMILY SSF55729 12 179 3.21E-24 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase MB46_11495 20324787cf4d6d8212d3ad0b7b9c8510 365 Pfam PF00534 Glycosyl transferases group 1 185 337 3.7E-8 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 MB46_11495 20324787cf4d6d8212d3ad0b7b9c8510 365 SUPERFAMILY SSF53756 5 356 1.15E-18 T 14-10-2018 MB46_11495 20324787cf4d6d8212d3ad0b7b9c8510 365 Gene3D G3DSA:3.40.50.2000 182 338 6.4E-16 T 14-10-2018 MB46_10970 6d26f63505d7a07d6c969a76b50a3ff3 322 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 119 301 1.0E-10 T 14-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase MB46_10970 6d26f63505d7a07d6c969a76b50a3ff3 322 SUPERFAMILY SSF56219 113 321 5.89E-22 T 14-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily MB46_10970 6d26f63505d7a07d6c969a76b50a3ff3 322 Gene3D G3DSA:3.60.10.10 111 322 2.3E-25 T 14-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily MB46_01570 67f0c550563c717a7e52ea7b1e01fe73 250 Gene3D G3DSA:3.40.30.10 68 249 1.2E-53 T 14-10-2018 MB46_01570 67f0c550563c717a7e52ea7b1e01fe73 250 Pfam PF13462 Thioredoxin 78 244 2.3E-35 T 14-10-2018 IPR012336 Thioredoxin-like fold MB46_01570 67f0c550563c717a7e52ea7b1e01fe73 250 SUPERFAMILY SSF52833 76 243 8.02E-42 T 14-10-2018 IPR036249 Thioredoxin-like superfamily MB46_19210 da4e2daca9c7f3fb02bf69a8612ba4a1 215 Gene3D G3DSA:3.30.450.180 30 205 5.2E-15 T 14-10-2018 MB46_20010 da4e2daca9c7f3fb02bf69a8612ba4a1 215 Gene3D G3DSA:3.30.450.180 30 205 5.2E-15 T 14-10-2018 MB46_06050 7ac8c44b126ffeb03bbdc5beeb4e8f27 140 TIGRFAM TIGR03561 organ_hyd_perox: peroxiredoxin, Ohr subfamily 4 137 3.6E-54 T 14-10-2018 IPR019953 Organic hydroperoxide resistance protein famiy GO:0006979 MB46_06050 7ac8c44b126ffeb03bbdc5beeb4e8f27 140 Pfam PF02566 OsmC-like protein 39 135 1.1E-18 T 14-10-2018 IPR003718 OsmC/Ohr family MB46_06050 7ac8c44b126ffeb03bbdc5beeb4e8f27 140 SUPERFAMILY SSF82784 1 137 4.84E-40 T 14-10-2018 IPR036102 OsmC/Ohr superfamily MB46_06050 7ac8c44b126ffeb03bbdc5beeb4e8f27 140 Gene3D G3DSA:2.20.25.10 1 44 4.2E-17 T 14-10-2018 MB46_06050 7ac8c44b126ffeb03bbdc5beeb4e8f27 140 Gene3D G3DSA:3.30.300.20 45 139 2.8E-33 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta MB46_07500 6ede3583bc2ae26b4db9639100e04ac5 142 SUPERFAMILY SSF46785 3 114 1.06E-33 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_07500 6ede3583bc2ae26b4db9639100e04ac5 142 Gene3D G3DSA:1.10.10.10 2 142 1.0E-39 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_07500 6ede3583bc2ae26b4db9639100e04ac5 142 Pfam PF01638 HxlR-like helix-turn-helix 16 99 1.3E-16 T 14-10-2018 IPR002577 Helix-turn-helix, HxlR type MB46_11310 2975a543820492f591c9a56162245a17 159 Gene3D G3DSA:2.40.280.10 3 129 2.5E-47 T 14-10-2018 IPR023620 Small protein B MB46_11310 2975a543820492f591c9a56162245a17 159 TIGRFAM TIGR00086 smpB: SsrA-binding protein 10 150 1.7E-56 T 14-10-2018 IPR000037 SsrA-binding protein GO:0003723 MB46_11310 2975a543820492f591c9a56162245a17 159 ProSitePatterns PS01317 SsrA-binding protein. 28 40 - T 14-10-2018 IPR020081 SsrA-binding protein, conserved site MB46_11310 2975a543820492f591c9a56162245a17 159 Hamap MF_00023 SsrA-binding protein [smpB]. 1 156 69.002 T 14-10-2018 IPR000037 SsrA-binding protein GO:0003723 MB46_11310 2975a543820492f591c9a56162245a17 159 Pfam PF01668 SmpB protein 10 151 5.6E-58 T 14-10-2018 IPR000037 SsrA-binding protein GO:0003723 MB46_11310 2975a543820492f591c9a56162245a17 159 SUPERFAMILY SSF74982 3 133 6.8E-51 T 14-10-2018 IPR023620 Small protein B MB46_11310 2975a543820492f591c9a56162245a17 159 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 10 133 3.0E-47 T 14-10-2018 IPR000037 SsrA-binding protein GO:0003723 MB46_13455 267e2faf01d54c87e357aec90a48240a 396 Gene3D G3DSA:2.40.30.10 208 336 1.5E-52 T 14-10-2018 MB46_13455 267e2faf01d54c87e357aec90a48240a 396 SUPERFAMILY SSF50465 304 396 3.17E-34 T 14-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal MB46_13455 267e2faf01d54c87e357aec90a48240a 396 Pfam PF00009 Elongation factor Tu GTP binding domain 10 203 3.1E-57 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MB46_13455 267e2faf01d54c87e357aec90a48240a 396 Pfam PF03143 Elongation factor Tu C-terminal domain 300 394 4.9E-31 T 14-10-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal MB46_13455 267e2faf01d54c87e357aec90a48240a 396 SUPERFAMILY SSF52540 6 221 7.3E-59 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_13455 267e2faf01d54c87e357aec90a48240a 396 SUPERFAMILY SSF50447 207 303 1.23E-30 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily MB46_13455 267e2faf01d54c87e357aec90a48240a 396 PRINTS PR00315 GTP-binding elongation factor signature 133 142 6.7E-24 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MB46_13455 267e2faf01d54c87e357aec90a48240a 396 PRINTS PR00315 GTP-binding elongation factor signature 14 27 6.7E-24 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MB46_13455 267e2faf01d54c87e357aec90a48240a 396 PRINTS PR00315 GTP-binding elongation factor signature 96 107 6.7E-24 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MB46_13455 267e2faf01d54c87e357aec90a48240a 396 PRINTS PR00315 GTP-binding elongation factor signature 80 90 6.7E-24 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MB46_13455 267e2faf01d54c87e357aec90a48240a 396 PRINTS PR00315 GTP-binding elongation factor signature 60 68 6.7E-24 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MB46_13455 267e2faf01d54c87e357aec90a48240a 396 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 150 5.7E-13 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MB46_13455 267e2faf01d54c87e357aec90a48240a 396 Gene3D G3DSA:3.40.50.300 1 205 4.3E-67 T 14-10-2018 MB46_13455 267e2faf01d54c87e357aec90a48240a 396 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 53 68 - T 14-10-2018 IPR031157 Tr-type G domain, conserved site MB46_13455 267e2faf01d54c87e357aec90a48240a 396 Pfam PF03144 Elongation factor Tu domain 2 227 295 6.6E-18 T 14-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 MB46_13455 267e2faf01d54c87e357aec90a48240a 396 Gene3D G3DSA:2.40.30.10 340 395 1.3E-27 T 14-10-2018 MB46_13455 267e2faf01d54c87e357aec90a48240a 396 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 2 396 3.9E-211 T 14-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MB46_13455 267e2faf01d54c87e357aec90a48240a 396 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 396 57.8 T 14-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MB46_05640 3726aea9ed0616fd3033b0668bd2e274 212 SUPERFAMILY SSF51366 5 203 2.98E-53 T 14-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 MB46_05640 3726aea9ed0616fd3033b0668bd2e274 212 Hamap MF_00135 N-(5'-phosphoribosyl)anthranilate isomerase [trpF]. 4 206 34.194 T 14-10-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 MB46_05640 3726aea9ed0616fd3033b0668bd2e274 212 Pfam PF00697 N-(5'phosphoribosyl)anthranilate (PRA) isomerase 6 201 1.8E-48 T 14-10-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 MB46_05640 3726aea9ed0616fd3033b0668bd2e274 212 Gene3D G3DSA:3.20.20.70 2 208 1.7E-65 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MB46_01525 fb9f4f6c065609f23ceed6d75838006c 287 Gene3D G3DSA:3.20.20.70 1 284 1.6E-95 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MB46_01525 fb9f4f6c065609f23ceed6d75838006c 287 SUPERFAMILY SSF51569 4 284 8.2E-88 T 14-10-2018 MB46_01525 fb9f4f6c065609f23ceed6d75838006c 287 Pfam PF01116 Fructose-bisphosphate aldolase class-II 7 283 3.7E-89 T 14-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 MB46_01525 fb9f4f6c065609f23ceed6d75838006c 287 PIRSF PIRSF001359 1 284 5.2E-91 T 14-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 MB46_01525 fb9f4f6c065609f23ceed6d75838006c 287 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 4 284 4.5E-80 T 14-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 MB46_00075 7da6a4b06666c5c0002c9c361985038d 366 Gene3D G3DSA:3.40.50.300 4 223 9.5E-63 T 14-10-2018 MB46_00075 7da6a4b06666c5c0002c9c361985038d 366 Gene3D G3DSA:2.40.50.940 224 351 4.9E-27 T 14-10-2018 MB46_00075 7da6a4b06666c5c0002c9c361985038d 366 Pfam PF08402 TOBE domain 277 350 2.2E-5 T 14-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 MB46_00075 7da6a4b06666c5c0002c9c361985038d 366 SUPERFAMILY SSF52540 4 245 6.36E-84 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_00075 7da6a4b06666c5c0002c9c361985038d 366 SMART SM00382 30 213 3.9E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_00075 7da6a4b06666c5c0002c9c361985038d 366 Pfam PF00005 ABC transporter 22 163 4.1E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_00075 7da6a4b06666c5c0002c9c361985038d 366 SUPERFAMILY SSF50331 238 358 1.41E-25 T 14-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal MB46_00075 7da6a4b06666c5c0002c9c361985038d 366 Gene3D G3DSA:2.40.50.140 284 342 4.9E-27 T 14-10-2018 MB46_00075 7da6a4b06666c5c0002c9c361985038d 366 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_00800 1bc3158410ebfddc37844de06a9954ad 202 Gene3D G3DSA:1.10.10.10 2 87 2.5E-13 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_00800 1bc3158410ebfddc37844de06a9954ad 202 SUPERFAMILY SSF46785 1 95 9.28E-10 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_00800 1bc3158410ebfddc37844de06a9954ad 202 Pfam PF12840 Helix-turn-helix domain 11 68 1.4E-13 T 14-10-2018 MB46_13485 a382fd6648a5bfddd356826b430e5b96 399 SUPERFAMILY SSF53901 7 274 1.41E-80 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 MB46_13485 a382fd6648a5bfddd356826b430e5b96 399 ProSitePatterns PS00737 Thiolases signature 2. 343 359 - T 14-10-2018 IPR020613 Thiolase, conserved site GO:0016747 MB46_13485 a382fd6648a5bfddd356826b430e5b96 399 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 10 394 1.7E-126 T 14-10-2018 IPR002155 Thiolase GO:0016747 MB46_13485 a382fd6648a5bfddd356826b430e5b96 399 Gene3D G3DSA:3.40.47.10 9 280 1.1E-130 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 MB46_13485 a382fd6648a5bfddd356826b430e5b96 399 Pfam PF02803 Thiolase, C-terminal domain 275 394 3.3E-38 T 14-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 MB46_13485 a382fd6648a5bfddd356826b430e5b96 399 PIRSF PIRSF000429 2 397 2.8E-110 T 14-10-2018 IPR002155 Thiolase GO:0016747 MB46_13485 a382fd6648a5bfddd356826b430e5b96 399 Pfam PF00108 Thiolase, N-terminal domain 8 266 4.5E-92 T 14-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 MB46_13485 a382fd6648a5bfddd356826b430e5b96 399 ProSitePatterns PS00099 Thiolases active site. 378 391 - T 14-10-2018 IPR020610 Thiolase, active site GO:0016747 MB46_13485 a382fd6648a5bfddd356826b430e5b96 399 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 88 106 - T 14-10-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0016747 MB46_13485 a382fd6648a5bfddd356826b430e5b96 399 SUPERFAMILY SSF53901 276 394 4.91E-31 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 MB46_13485 a382fd6648a5bfddd356826b430e5b96 399 Gene3D G3DSA:3.40.47.10 130 393 1.1E-130 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 MB46_17970 363baefc0e7c2e6fc3edea7a5282af5d 123 Gene3D G3DSA:3.10.180.10 2 121 4.4E-13 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MB46_17970 363baefc0e7c2e6fc3edea7a5282af5d 123 SUPERFAMILY SSF54593 1 118 1.14E-18 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MB46_17970 363baefc0e7c2e6fc3edea7a5282af5d 123 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 114 1.5E-5 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MB46_15870 ed5e8212e54a28ce562ca0f638ecebd9 1229 Gene3D G3DSA:3.40.50.300 1022 1206 2.9E-31 T 14-10-2018 MB46_15870 ed5e8212e54a28ce562ca0f638ecebd9 1229 Gene3D G3DSA:3.40.50.300 820 1002 9.1E-28 T 14-10-2018 MB46_15870 ed5e8212e54a28ce562ca0f638ecebd9 1229 Pfam PF13604 AAA domain 831 990 1.9E-12 T 14-10-2018 MB46_15870 ed5e8212e54a28ce562ca0f638ecebd9 1229 Pfam PF13482 RNase_H superfamily 339 545 3.5E-12 T 14-10-2018 IPR038720 YprB, ribonuclease H-like domain MB46_15870 ed5e8212e54a28ce562ca0f638ecebd9 1229 Pfam PF13087 AAA domain 1016 1193 9.8E-22 T 14-10-2018 MB46_15870 ed5e8212e54a28ce562ca0f638ecebd9 1229 TIGRFAM TIGR03491 TIGR03491: putative RecB family nuclease, TM0106 family 100 545 1.6E-41 T 14-10-2018 IPR019993 RecB family nuclease, TM0106, putative MB46_15870 ed5e8212e54a28ce562ca0f638ecebd9 1229 SUPERFAMILY SSF52540 832 1196 3.68E-39 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_07715 cfb38b42a11ba9f95685dd72ecd1b263 225 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 10 217 1.7E-74 T 14-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 MB46_07715 cfb38b42a11ba9f95685dd72ecd1b263 225 Gene3D G3DSA:3.20.20.70 4 221 1.1E-75 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MB46_07715 cfb38b42a11ba9f95685dd72ecd1b263 225 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 137 159 - T 14-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 MB46_07715 cfb38b42a11ba9f95685dd72ecd1b263 225 Pfam PF00834 Ribulose-phosphate 3 epimerase family 10 204 7.8E-73 T 14-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 MB46_07715 cfb38b42a11ba9f95685dd72ecd1b263 225 PIRSF PIRSF001461 5 224 4.2E-84 T 14-10-2018 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 MB46_07715 cfb38b42a11ba9f95685dd72ecd1b263 225 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 35 49 - T 14-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 MB46_07715 cfb38b42a11ba9f95685dd72ecd1b263 225 SUPERFAMILY SSF51366 8 218 1.41E-61 T 14-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 MB46_00210 0fad050c24cb38f678a2e5b5d20d9612 342 SUPERFAMILY SSF53822 64 334 1.99E-51 T 14-10-2018 IPR028082 Periplasmic binding protein-like I MB46_00210 0fad050c24cb38f678a2e5b5d20d9612 342 Pfam PF00356 Bacterial regulatory proteins, lacI family 5 49 1.9E-13 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MB46_00210 0fad050c24cb38f678a2e5b5d20d9612 342 Gene3D G3DSA:3.40.50.2300 162 291 3.0E-52 T 14-10-2018 MB46_00210 0fad050c24cb38f678a2e5b5d20d9612 342 Pfam PF13377 Periplasmic binding protein-like domain 170 331 1.1E-27 T 14-10-2018 MB46_00210 0fad050c24cb38f678a2e5b5d20d9612 342 SUPERFAMILY SSF47413 2 54 5.63E-14 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MB46_00210 0fad050c24cb38f678a2e5b5d20d9612 342 Gene3D G3DSA:1.10.260.40 1 58 3.6E-18 T 14-10-2018 MB46_00210 0fad050c24cb38f678a2e5b5d20d9612 342 Gene3D G3DSA:3.40.50.2300 65 309 3.0E-52 T 14-10-2018 MB46_00210 0fad050c24cb38f678a2e5b5d20d9612 342 SMART SM00354 3 74 1.5E-11 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MB46_18015 406b6c8df7efcaa459bb15a0b7e476b5 301 Pfam PF00892 EamA-like transporter family 146 273 3.2E-14 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MB46_18015 406b6c8df7efcaa459bb15a0b7e476b5 301 SUPERFAMILY SSF103481 184 284 1.31E-9 T 14-10-2018 MB46_18015 406b6c8df7efcaa459bb15a0b7e476b5 301 SUPERFAMILY SSF103481 46 136 3.4E-6 T 14-10-2018 MB46_05785 1a692a2521dc8fff3ccd45b83d7c4ff2 368 Pfam PF00107 Zinc-binding dehydrogenase 195 327 8.1E-16 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 MB46_05785 1a692a2521dc8fff3ccd45b83d7c4ff2 368 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 31 143 8.8E-24 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MB46_05785 1a692a2521dc8fff3ccd45b83d7c4ff2 368 SUPERFAMILY SSF51735 154 329 1.25E-24 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_05785 1a692a2521dc8fff3ccd45b83d7c4ff2 368 Gene3D G3DSA:3.90.180.10 29 364 2.5E-74 T 14-10-2018 MB46_05785 1a692a2521dc8fff3ccd45b83d7c4ff2 368 SUPERFAMILY SSF50129 18 178 7.08E-34 T 14-10-2018 IPR011032 GroES-like superfamily MB46_05785 1a692a2521dc8fff3ccd45b83d7c4ff2 368 TIGRFAM TIGR03366 HpnZ_proposed: putative phosphonate catabolism associated alcohol dehydrogenase 29 348 1.5E-117 T 14-10-2018 IPR017743 Alcohol dehydrogenase, phosphonate catabolism-associated, putative MB46_05785 1a692a2521dc8fff3ccd45b83d7c4ff2 368 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 64 78 - T 14-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 MB46_05785 1a692a2521dc8fff3ccd45b83d7c4ff2 368 Gene3D G3DSA:3.40.50.720 167 315 2.5E-74 T 14-10-2018 MB46_15440 d4c7a4590966e9a35e67b6450e877048 309 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 253 266 - T 14-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 MB46_15440 d4c7a4590966e9a35e67b6450e877048 309 Hamap MF_01987 Ribokinase [rbsK]. 3 308 24.499 T 14-10-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 MB46_15440 d4c7a4590966e9a35e67b6450e877048 309 PRINTS PR00990 Ribokinase signature 34 53 4.0E-31 T 14-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 MB46_15440 d4c7a4590966e9a35e67b6450e877048 309 PRINTS PR00990 Ribokinase signature 105 118 4.0E-31 T 14-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 MB46_15440 d4c7a4590966e9a35e67b6450e877048 309 PRINTS PR00990 Ribokinase signature 220 231 4.0E-31 T 14-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 MB46_15440 d4c7a4590966e9a35e67b6450e877048 309 PRINTS PR00990 Ribokinase signature 7 28 4.0E-31 T 14-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 MB46_15440 d4c7a4590966e9a35e67b6450e877048 309 PRINTS PR00990 Ribokinase signature 171 186 4.0E-31 T 14-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 MB46_15440 d4c7a4590966e9a35e67b6450e877048 309 Pfam PF00294 pfkB family carbohydrate kinase 3 301 2.9E-58 T 14-10-2018 IPR011611 Carbohydrate kinase PfkB MB46_15440 d4c7a4590966e9a35e67b6450e877048 309 SUPERFAMILY SSF53613 4 307 1.71E-70 T 14-10-2018 IPR029056 Ribokinase-like MB46_15440 d4c7a4590966e9a35e67b6450e877048 309 Gene3D G3DSA:3.40.1190.20 1 309 2.3E-86 T 14-10-2018 IPR029056 Ribokinase-like MB46_17530 702285cdce0cdf9bbed5fd3bfabbbdb0 446 Gene3D G3DSA:3.40.50.10860 53 188 5.0E-162 T 14-10-2018 MB46_17530 702285cdce0cdf9bbed5fd3bfabbbdb0 446 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 55 183 4.5E-49 T 14-10-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 MB46_17530 702285cdce0cdf9bbed5fd3bfabbbdb0 446 Gene3D G3DSA:1.10.285.10 383 446 6.9E-9 T 14-10-2018 MB46_17530 702285cdce0cdf9bbed5fd3bfabbbdb0 446 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 234 254 3.5E-29 T 14-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 MB46_17530 702285cdce0cdf9bbed5fd3bfabbbdb0 446 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 112 126 3.5E-29 T 14-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 MB46_17530 702285cdce0cdf9bbed5fd3bfabbbdb0 446 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 370 381 3.5E-29 T 14-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 MB46_17530 702285cdce0cdf9bbed5fd3bfabbbdb0 446 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 192 214 3.5E-29 T 14-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 MB46_17530 702285cdce0cdf9bbed5fd3bfabbbdb0 446 SUPERFAMILY SSF53223 5 195 5.44E-75 T 14-10-2018 MB46_17530 702285cdce0cdf9bbed5fd3bfabbbdb0 446 PIRSF PIRSF000185 20 446 4.1E-115 T 14-10-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 MB46_17530 702285cdce0cdf9bbed5fd3bfabbbdb0 446 Gene3D G3DSA:3.40.50.720 208 371 5.0E-162 T 14-10-2018 MB46_17530 702285cdce0cdf9bbed5fd3bfabbbdb0 446 SMART SM00839 203 444 5.2E-84 T 14-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 MB46_17530 702285cdce0cdf9bbed5fd3bfabbbdb0 446 Gene3D G3DSA:1.10.285.10 6 382 5.0E-162 T 14-10-2018 MB46_17530 702285cdce0cdf9bbed5fd3bfabbbdb0 446 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 201 444 6.8E-85 T 14-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 MB46_17530 702285cdce0cdf9bbed5fd3bfabbbdb0 446 SUPERFAMILY SSF51735 201 445 4.33E-73 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_08685 d5d1b05589651916c3872af979e30328 236 SUPERFAMILY SSF52317 22 232 7.42E-47 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like MB46_08685 d5d1b05589651916c3872af979e30328 236 Gene3D G3DSA:3.40.50.880 20 235 3.2E-73 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like MB46_08685 d5d1b05589651916c3872af979e30328 236 Hamap MF_01615 Pyridoxal 5'-phosphate synthase subunit PdxT [pdxT]. 23 231 37.547 T 14-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 MB46_08685 d5d1b05589651916c3872af979e30328 236 Pfam PF01174 SNO glutamine amidotransferase family 25 232 8.0E-55 T 14-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 MB46_08685 d5d1b05589651916c3872af979e30328 236 ProSitePatterns PS01236 PdxT/SNO family family signature. 60 70 - T 14-10-2018 IPR021196 PdxT/SNO family, conserved site KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 MB46_08685 d5d1b05589651916c3872af979e30328 236 TIGRFAM TIGR03800 PLP_synth_Pdx2: pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2 23 229 4.5E-63 T 14-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 MB46_08685 d5d1b05589651916c3872af979e30328 236 PIRSF PIRSF005639 18 236 6.9E-69 T 14-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 MB46_19380 4e4647d07006bc23a99de9dd987259ad 286 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 92 278 1.9E-6 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_19380 4e4647d07006bc23a99de9dd987259ad 286 Gene3D G3DSA:1.10.3720.10 45 285 7.6E-48 T 14-10-2018 IPR035906 MetI-like superfamily MB46_19380 4e4647d07006bc23a99de9dd987259ad 286 SUPERFAMILY SSF161098 50 274 1.09E-39 T 14-10-2018 IPR035906 MetI-like superfamily MB46_13785 bc9a64d184e1a34f49e15a27a4bf8c57 312 Gene3D G3DSA:3.60.130.10 9 311 9.5E-94 T 14-10-2018 MB46_13785 bc9a64d184e1a34f49e15a27a4bf8c57 312 SUPERFAMILY SSF51197 16 288 6.87E-80 T 14-10-2018 MB46_13785 bc9a64d184e1a34f49e15a27a4bf8c57 312 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 18 281 2.8E-56 T 14-10-2018 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 MB46_07940 df86916b315aadc9d52791fdd5b9c7de 427 Pfam PF11268 Protein of unknown function (DUF3071) 1 172 1.5E-47 T 14-10-2018 IPR021421 Protein of unknown function DUF3071 MB46_08690 9bb1f3d75751091d2e63a9db41910d06 894 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 556 2.7E-128 T 14-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 MB46_08690 9bb1f3d75751091d2e63a9db41910d06 894 SUPERFAMILY SSF144010 706 890 7.98E-8 T 14-10-2018 MB46_08690 9bb1f3d75751091d2e63a9db41910d06 894 SUPERFAMILY SSF52402 249 612 1.91E-52 T 14-10-2018 MB46_08690 9bb1f3d75751091d2e63a9db41910d06 894 Pfam PF13537 Glutamine amidotransferase domain 44 167 7.1E-45 T 14-10-2018 IPR017932 Glutamine amidotransferase type 2 domain MB46_08690 9bb1f3d75751091d2e63a9db41910d06 894 Pfam PF00733 Asparagine synthase 253 621 1.2E-63 T 14-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 MB46_08690 9bb1f3d75751091d2e63a9db41910d06 894 Gene3D G3DSA:3.60.20.10 4 184 5.7E-63 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MB46_08690 9bb1f3d75751091d2e63a9db41910d06 894 SUPERFAMILY SSF56235 1 213 2.14E-57 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MB46_03220 09ab604f3097091a2ddb3edbce76eb7c 76 Pfam PF13275 S4 domain 9 72 1.5E-26 T 14-10-2018 MB46_03220 09ab604f3097091a2ddb3edbce76eb7c 76 Gene3D G3DSA:3.10.290.10 1 73 3.8E-23 T 14-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 MB46_03220 09ab604f3097091a2ddb3edbce76eb7c 76 SUPERFAMILY SSF55174 5 72 1.15E-19 T 14-10-2018 MB46_05530 d41310e90090798a83198a6e1d937c58 300 SUPERFAMILY SSF50129 1 147 1.19E-29 T 14-10-2018 IPR011032 GroES-like superfamily MB46_05530 d41310e90090798a83198a6e1d937c58 300 Gene3D G3DSA:3.90.180.10 9 296 2.1E-54 T 14-10-2018 MB46_05530 d41310e90090798a83198a6e1d937c58 300 SMART SM00829 10 297 3.8E-10 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MB46_05530 d41310e90090798a83198a6e1d937c58 300 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 92 1.1E-8 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MB46_05530 d41310e90090798a83198a6e1d937c58 300 SUPERFAMILY SSF51735 114 233 1.21E-17 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_05530 d41310e90090798a83198a6e1d937c58 300 Gene3D G3DSA:3.40.50.720 124 250 2.1E-54 T 14-10-2018 MB46_02530 65232af5bb16adfbbeff9a6dc627c0d9 484 Pfam PF04230 Polysaccharide pyruvyl transferase 11 317 6.9E-30 T 14-10-2018 IPR007345 Polysaccharide pyruvyl transferase MB46_13700 0c0a4efec618062078d16ee7e809514b 377 Gene3D G3DSA:3.40.50.720 6 144 5.5E-52 T 14-10-2018 MB46_13700 0c0a4efec618062078d16ee7e809514b 377 PIRSF PIRSF000148 6 377 8.2E-57 T 14-10-2018 MB46_13700 0c0a4efec618062078d16ee7e809514b 377 Gene3D G3DSA:3.30.360.10 145 357 2.9E-77 T 14-10-2018 MB46_13700 0c0a4efec618062078d16ee7e809514b 377 SUPERFAMILY SSF51735 8 153 2.05E-45 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_13700 0c0a4efec618062078d16ee7e809514b 377 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 9 126 9.7E-19 T 14-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 MB46_13700 0c0a4efec618062078d16ee7e809514b 377 ProSitePatterns PS01103 Aspartate-semialdehyde dehydrogenase signature. 268 282 - T 14-10-2018 IPR000319 Aspartate-semialdehyde dehydrogenase, conserved site GO:0004073|GO:0006520|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 MB46_13700 0c0a4efec618062078d16ee7e809514b 377 TIGRFAM TIGR01745 asd_gamma: aspartate-semialdehyde dehydrogenase 8 373 3.9E-172 T 14-10-2018 IPR011534 Aspartate-semialdehyde dehydrogenase, gamma-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 MB46_13700 0c0a4efec618062078d16ee7e809514b 377 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 150 360 3.5E-49 T 14-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 MB46_13700 0c0a4efec618062078d16ee7e809514b 377 SUPERFAMILY SSF55347 140 361 2.32E-70 T 14-10-2018 MB46_13700 0c0a4efec618062078d16ee7e809514b 377 SMART SM00859 8 128 5.5E-17 T 14-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 MB46_00785 5a4e20ac4f907fde155c2f8a0aa734d1 581 Pfam PF05524 PEP-utilising enzyme, N-terminal 17 140 1.7E-14 T 14-10-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 MB46_00785 5a4e20ac4f907fde155c2f8a0aa734d1 581 Gene3D G3DSA:3.50.30.10 17 248 3.6E-44 T 14-10-2018 MB46_00785 5a4e20ac4f907fde155c2f8a0aa734d1 581 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 269 544 8.4E-73 T 14-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 MB46_00785 5a4e20ac4f907fde155c2f8a0aa734d1 581 Gene3D G3DSA:1.10.274.10 34 160 3.6E-44 T 14-10-2018 IPR036618 PtsI, HPr-binding domain superfamily GO:0009401 MB46_00785 5a4e20ac4f907fde155c2f8a0aa734d1 581 SUPERFAMILY SSF47831 49 157 9.02E-14 T 14-10-2018 IPR036618 PtsI, HPr-binding domain superfamily GO:0009401 MB46_00785 5a4e20ac4f907fde155c2f8a0aa734d1 581 Gene3D G3DSA:3.20.20.60 263 574 3.4E-89 T 14-10-2018 MB46_00785 5a4e20ac4f907fde155c2f8a0aa734d1 581 SUPERFAMILY SSF52009 139 252 1.57E-24 T 14-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 MB46_00785 5a4e20ac4f907fde155c2f8a0aa734d1 581 Pfam PF00391 PEP-utilising enzyme, mobile domain 170 238 1.1E-17 T 14-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 MB46_00785 5a4e20ac4f907fde155c2f8a0aa734d1 581 PIRSF PIRSF000732 10 574 2.3E-137 T 14-10-2018 IPR024692 Phosphotransferase system, enzyme I GO:0008965|GO:0009401 MB46_00785 5a4e20ac4f907fde155c2f8a0aa734d1 581 SUPERFAMILY SSF51621 266 546 5.14E-77 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 MB46_00785 5a4e20ac4f907fde155c2f8a0aa734d1 581 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 301 320 2.1E-12 T 14-10-2018 MB46_00785 5a4e20ac4f907fde155c2f8a0aa734d1 581 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 445 460 2.1E-12 T 14-10-2018 MB46_00785 5a4e20ac4f907fde155c2f8a0aa734d1 581 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 462 477 2.1E-12 T 14-10-2018 MB46_06690 2ba2e08654e000d0db1aa41fe3008157 109 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 61 76 5.3E-6 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MB46_06690 2ba2e08654e000d0db1aa41fe3008157 109 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 46 61 5.3E-6 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MB46_06690 2ba2e08654e000d0db1aa41fe3008157 109 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 14 29 5.3E-6 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MB46_06690 2ba2e08654e000d0db1aa41fe3008157 109 Pfam PF12840 Helix-turn-helix domain 15 70 2.2E-11 T 14-10-2018 MB46_06690 2ba2e08654e000d0db1aa41fe3008157 109 Gene3D G3DSA:1.10.10.10 4 98 2.4E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_06690 2ba2e08654e000d0db1aa41fe3008157 109 SUPERFAMILY SSF46785 12 93 1.96E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_06690 2ba2e08654e000d0db1aa41fe3008157 109 SMART SM00418 12 90 1.9E-23 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MB46_08210 986010d10b5a86d456905d4dfc576b71 175 Hamap MF_01197 Cell division protein SepF [sepF]. 2 165 20.333 T 14-10-2018 IPR023052 Cell division protein SepF GO:0090529 MB46_08210 986010d10b5a86d456905d4dfc576b71 175 Gene3D G3DSA:3.30.110.150 83 164 1.2E-25 T 14-10-2018 IPR038594 SepF-like superfamily MB46_08210 986010d10b5a86d456905d4dfc576b71 175 Pfam PF04472 Cell division protein SepF 86 157 5.7E-24 T 14-10-2018 IPR007561 Cell division protein SepF/SepF-related GO:0090529 MB46_11145 7e76ca87932cd7452c4225a374ead2ea 347 Gene3D G3DSA:3.40.50.2300 75 318 5.1E-69 T 14-10-2018 MB46_11145 7e76ca87932cd7452c4225a374ead2ea 347 SMART SM00354 21 91 1.5E-30 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MB46_11145 7e76ca87932cd7452c4225a374ead2ea 347 Gene3D G3DSA:1.10.260.40 14 74 6.1E-21 T 14-10-2018 MB46_11145 7e76ca87932cd7452c4225a374ead2ea 347 SUPERFAMILY SSF53822 80 342 2.94E-62 T 14-10-2018 IPR028082 Periplasmic binding protein-like I MB46_11145 7e76ca87932cd7452c4225a374ead2ea 347 Pfam PF13377 Periplasmic binding protein-like domain 184 341 8.5E-34 T 14-10-2018 MB46_11145 7e76ca87932cd7452c4225a374ead2ea 347 Gene3D G3DSA:3.40.50.2300 176 301 5.1E-69 T 14-10-2018 MB46_11145 7e76ca87932cd7452c4225a374ead2ea 347 Pfam PF00356 Bacterial regulatory proteins, lacI family 23 68 3.1E-17 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MB46_11145 7e76ca87932cd7452c4225a374ead2ea 347 SUPERFAMILY SSF47413 22 79 1.26E-17 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MB46_01820 717d158d66a41661d00c77d23130e2b7 580 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 536 553 - T 14-10-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MB46_01820 717d158d66a41661d00c77d23130e2b7 580 SUPERFAMILY SSF56059 114 324 1.75E-61 T 14-10-2018 MB46_01820 717d158d66a41661d00c77d23130e2b7 580 Pfam PF00289 Biotin carboxylase, N-terminal domain 2 109 6.0E-43 T 14-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MB46_01820 717d158d66a41661d00c77d23130e2b7 580 SMART SM00878 334 443 1.9E-57 T 14-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MB46_01820 717d158d66a41661d00c77d23130e2b7 580 SUPERFAMILY SSF51230 507 579 1.7E-16 T 14-10-2018 IPR011053 Single hybrid motif MB46_01820 717d158d66a41661d00c77d23130e2b7 580 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 115 321 2.4E-75 T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MB46_01820 717d158d66a41661d00c77d23130e2b7 580 SUPERFAMILY SSF51246 328 446 4.19E-38 T 14-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 MB46_01820 717d158d66a41661d00c77d23130e2b7 580 SUPERFAMILY SSF52440 1 112 7.91E-47 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily MB46_01820 717d158d66a41661d00c77d23130e2b7 580 Gene3D G3DSA:2.40.50.100 509 580 6.3E-19 T 14-10-2018 MB46_01820 717d158d66a41661d00c77d23130e2b7 580 Pfam PF00364 Biotin-requiring enzyme 513 579 4.8E-12 T 14-10-2018 IPR000089 Biotin/lipoyl attachment MB46_01820 717d158d66a41661d00c77d23130e2b7 580 Pfam PF02785 Biotin carboxylase C-terminal domain 334 443 9.1E-36 T 14-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MB46_01820 717d158d66a41661d00c77d23130e2b7 580 Gene3D G3DSA:3.30.470.130 1 448 2.2E-180 T 14-10-2018 MB46_01820 717d158d66a41661d00c77d23130e2b7 580 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 285 292 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MB46_03120 1c85d2c541c9f6b767660be5bceed317 407 SUPERFAMILY SSF51556 58 354 3.41E-59 T 14-10-2018 IPR032466 Metal-dependent hydrolase MB46_03120 1c85d2c541c9f6b767660be5bceed317 407 Pfam PF01979 Amidohydrolase family 56 381 2.9E-9 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 MB46_03120 1c85d2c541c9f6b767660be5bceed317 407 SUPERFAMILY SSF51338 6 404 1.48E-15 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 MB46_03120 1c85d2c541c9f6b767660be5bceed317 407 Gene3D G3DSA:3.20.20.140 59 366 3.2E-111 T 14-10-2018 MB46_03120 1c85d2c541c9f6b767660be5bceed317 407 Hamap MF_00372 Imidazolonepropionase [hutI]. 2 406 39.717 T 14-10-2018 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 MB46_03120 1c85d2c541c9f6b767660be5bceed317 407 Gene3D G3DSA:2.30.40.10 15 403 3.2E-111 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 MB46_16855 c6a091a809659cd51cd3284e020d4a79 636 SUPERFAMILY SSF52833 19 161 6.11E-28 T 14-10-2018 IPR036249 Thioredoxin-like superfamily MB46_16855 c6a091a809659cd51cd3284e020d4a79 636 Pfam PF00578 AhpC/TSA family 15 127 1.6E-8 T 14-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 MB46_16855 c6a091a809659cd51cd3284e020d4a79 636 Gene3D G3DSA:3.40.30.10 4 158 3.3E-31 T 14-10-2018 MB46_16855 c6a091a809659cd51cd3284e020d4a79 636 Pfam PF01436 NHL repeat 425 452 2.7E-5 T 14-10-2018 IPR001258 NHL repeat GO:0005515 MB46_16855 c6a091a809659cd51cd3284e020d4a79 636 SUPERFAMILY SSF101898 165 499 1.02E-31 T 14-10-2018 MB46_16855 c6a091a809659cd51cd3284e020d4a79 636 Gene3D G3DSA:2.40.10.500 168 273 8.1E-6 T 14-10-2018 MB46_16855 c6a091a809659cd51cd3284e020d4a79 636 Gene3D G3DSA:2.120.10.30 320 453 1.8E-27 T 14-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like MB46_11995 a40ff264cd11d94bf13d6c01ffd93864 134 SUPERFAMILY SSF46767 3 65 4.84E-11 T 14-10-2018 IPR036217 Methylated DNA-protein cysteine methyltransferase, DNA binding domain Reactome: R-HSA-5657655 MB46_11995 a40ff264cd11d94bf13d6c01ffd93864 134 Gene3D G3DSA:1.10.10.10 2 107 4.1E-18 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_11995 a40ff264cd11d94bf13d6c01ffd93864 134 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 6 65 1.7E-13 T 14-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 MB46_13415 a5ba0aaf22e95229a6b125ea85b5c448 93 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 6.2E-23 T 14-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MB46_13415 a5ba0aaf22e95229a6b125ea85b5c448 93 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 6.2E-23 T 14-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MB46_13415 a5ba0aaf22e95229a6b125ea85b5c448 93 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 6.2E-23 T 14-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MB46_13415 a5ba0aaf22e95229a6b125ea85b5c448 93 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 24.499 T 14-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MB46_13415 a5ba0aaf22e95229a6b125ea85b5c448 93 Gene3D G3DSA:3.30.860.10 1 93 2.4E-38 T 14-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MB46_13415 a5ba0aaf22e95229a6b125ea85b5c448 93 Pfam PF00203 Ribosomal protein S19 3 83 4.0E-34 T 14-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MB46_13415 a5ba0aaf22e95229a6b125ea85b5c448 93 SUPERFAMILY SSF54570 3 84 1.96E-33 T 14-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MB46_13415 a5ba0aaf22e95229a6b125ea85b5c448 93 PIRSF PIRSF002144 1 93 3.8E-30 T 14-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MB46_13415 a5ba0aaf22e95229a6b125ea85b5c448 93 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 92 9.1E-45 T 14-10-2018 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 MB46_13415 a5ba0aaf22e95229a6b125ea85b5c448 93 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 14-10-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MB46_15950 460d376c5b9d81a35ecdf6f6d9e79d4d 267 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 80 258 3.0E-8 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_15950 460d376c5b9d81a35ecdf6f6d9e79d4d 267 SUPERFAMILY SSF161098 18 256 2.49E-34 T 14-10-2018 IPR035906 MetI-like superfamily MB46_15950 460d376c5b9d81a35ecdf6f6d9e79d4d 267 Gene3D G3DSA:1.10.3720.10 9 265 8.5E-36 T 14-10-2018 IPR035906 MetI-like superfamily MB46_12285 1bc3ea4d9f104f53349d2b3ebc2551b2 431 Pfam PF07690 Major Facilitator Superfamily 37 289 3.7E-25 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MB46_12285 1bc3ea4d9f104f53349d2b3ebc2551b2 431 Gene3D G3DSA:1.20.1250.20 26 424 1.7E-46 T 14-10-2018 MB46_12285 1bc3ea4d9f104f53349d2b3ebc2551b2 431 SUPERFAMILY SSF103473 25 412 3.79E-56 T 14-10-2018 IPR036259 MFS transporter superfamily MB46_08820 d97b37b4e5cdb40a4a9c8f830fe16102 413 Pfam PF07690 Major Facilitator Superfamily 223 403 3.9E-12 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MB46_08820 d97b37b4e5cdb40a4a9c8f830fe16102 413 Pfam PF07690 Major Facilitator Superfamily 23 188 1.1E-9 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MB46_08820 d97b37b4e5cdb40a4a9c8f830fe16102 413 SUPERFAMILY SSF103473 8 396 5.23E-38 T 14-10-2018 IPR036259 MFS transporter superfamily MB46_08820 d97b37b4e5cdb40a4a9c8f830fe16102 413 Gene3D G3DSA:1.20.1250.20 218 405 6.2E-16 T 14-10-2018 MB46_08820 d97b37b4e5cdb40a4a9c8f830fe16102 413 Gene3D G3DSA:1.20.1250.20 18 193 1.6E-14 T 14-10-2018 MB46_03560 d4b875f7a0af38a63a9416e424df646d 156 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 4 20 1.2E-7 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 MB46_03560 d4b875f7a0af38a63a9416e424df646d 156 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 20 31 1.2E-7 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 MB46_03560 d4b875f7a0af38a63a9416e424df646d 156 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 31 50 1.2E-7 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 MB46_03560 d4b875f7a0af38a63a9416e424df646d 156 Gene3D G3DSA:3.30.70.920 57 146 2.2E-20 T 14-10-2018 MB46_03560 d4b875f7a0af38a63a9416e424df646d 156 Pfam PF13404 AsnC-type helix-turn-helix domain 4 45 5.7E-13 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 MB46_03560 d4b875f7a0af38a63a9416e424df646d 156 SUPERFAMILY SSF46785 3 64 4.07E-10 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_03560 d4b875f7a0af38a63a9416e424df646d 156 Gene3D G3DSA:1.10.10.10 1 54 1.5E-11 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_03560 d4b875f7a0af38a63a9416e424df646d 156 Pfam PF01037 Lrp/AsnC ligand binding domain 70 140 4.5E-15 T 14-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain MB46_03560 d4b875f7a0af38a63a9416e424df646d 156 SUPERFAMILY SSF54909 64 148 7.78E-18 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel MB46_03560 d4b875f7a0af38a63a9416e424df646d 156 SMART SM00344 4 110 2.3E-23 T 14-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 MB46_09450 d8c07c8ef9b0f4278dd33c1a464a87af 322 Pfam PF02146 Sir2 family 64 266 3.8E-38 T 14-10-2018 IPR003000 Sirtuin family GO:0070403 MB46_09450 d8c07c8ef9b0f4278dd33c1a464a87af 322 Gene3D G3DSA:3.40.50.1220 55 305 3.0E-68 T 14-10-2018 MB46_09450 d8c07c8ef9b0f4278dd33c1a464a87af 322 Gene3D G3DSA:3.30.1600.10 73 236 3.0E-68 T 14-10-2018 IPR026591 Sirtuin, catalytic core small domain superfamily MB46_09450 d8c07c8ef9b0f4278dd33c1a464a87af 322 SUPERFAMILY SSF52467 43 315 4.49E-69 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily MB46_07560 e8ee04851d08c17671173e734a17f0f7 416 PIRSF PIRSF006356 1 414 7.9E-127 T 14-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 MB46_07560 e8ee04851d08c17671173e734a17f0f7 416 SUPERFAMILY SSF55909 8 412 8.74E-128 T 14-10-2018 MB46_07560 e8ee04851d08c17671173e734a17f0f7 416 Gene3D G3DSA:1.10.3930.10 72 156 1.2E-142 T 14-10-2018 MB46_07560 e8ee04851d08c17671173e734a17f0f7 416 PRINTS PR01466 Bacterial arginine deiminase signature 157 175 1.6E-45 T 14-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 MB46_07560 e8ee04851d08c17671173e734a17f0f7 416 PRINTS PR01466 Bacterial arginine deiminase signature 185 200 1.6E-45 T 14-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 MB46_07560 e8ee04851d08c17671173e734a17f0f7 416 PRINTS PR01466 Bacterial arginine deiminase signature 350 367 1.6E-45 T 14-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 MB46_07560 e8ee04851d08c17671173e734a17f0f7 416 PRINTS PR01466 Bacterial arginine deiminase signature 6 26 1.6E-45 T 14-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 MB46_07560 e8ee04851d08c17671173e734a17f0f7 416 PRINTS PR01466 Bacterial arginine deiminase signature 370 384 1.6E-45 T 14-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 MB46_07560 e8ee04851d08c17671173e734a17f0f7 416 PRINTS PR01466 Bacterial arginine deiminase signature 393 411 1.6E-45 T 14-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 MB46_07560 e8ee04851d08c17671173e734a17f0f7 416 Pfam PF02274 Amidinotransferase 22 411 2.8E-107 T 14-10-2018 MB46_07560 e8ee04851d08c17671173e734a17f0f7 416 Hamap MF_00242 Arginine deiminase [arcA]. 5 414 45.925 T 14-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 MB46_07560 e8ee04851d08c17671173e734a17f0f7 416 Gene3D G3DSA:3.75.10.10 10 411 1.2E-142 T 14-10-2018 MB46_09735 66b3effe8684476dff7b4fe6d4983aee 341 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 257 338 1.1E-13 T 14-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 MB46_09735 66b3effe8684476dff7b4fe6d4983aee 341 Gene3D G3DSA:3.40.47.10 2 204 3.4E-60 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 MB46_09735 66b3effe8684476dff7b4fe6d4983aee 341 Gene3D G3DSA:3.40.47.10 205 341 4.4E-30 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 MB46_09735 66b3effe8684476dff7b4fe6d4983aee 341 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 123 211 2.3E-10 T 14-10-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 MB46_09735 66b3effe8684476dff7b4fe6d4983aee 341 SUPERFAMILY SSF53901 53 341 6.67E-35 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 MB46_09610 6618b5c60711b5294c66924cbb437684 239 Gene3D G3DSA:3.40.50.1820 2 230 9.4E-20 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_09610 6618b5c60711b5294c66924cbb437684 239 Pfam PF12697 Alpha/beta hydrolase family 6 222 9.8E-10 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MB46_09610 6618b5c60711b5294c66924cbb437684 239 SUPERFAMILY SSF53474 4 218 3.68E-18 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_10835 8e8af0bd95dcda78258ee29f9ce0ab8f 96 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 4 83 3.0E-22 T 14-10-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MB46_10835 8e8af0bd95dcda78258ee29f9ce0ab8f 96 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 4 87 7.7E-21 T 14-10-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MB46_10835 8e8af0bd95dcda78258ee29f9ce0ab8f 96 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 17 85 2.0E-21 T 14-10-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MB46_10835 8e8af0bd95dcda78258ee29f9ce0ab8f 96 Gene3D G3DSA:2.60.15.10 1 88 1.6E-22 T 14-10-2018 IPR036771 F0F1 ATP synthase delta/epsilon subunit, N-terminal Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MB46_10835 8e8af0bd95dcda78258ee29f9ce0ab8f 96 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 2 95 11.471 T 14-10-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MB46_10835 8e8af0bd95dcda78258ee29f9ce0ab8f 96 SUPERFAMILY SSF51344 3 84 2.09E-20 T 14-10-2018 IPR036771 F0F1 ATP synthase delta/epsilon subunit, N-terminal Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MB46_02780 1bb545a3a769df1570e583c54f19ce92 477 SUPERFAMILY SSF103473 44 468 1.1E-37 T 14-10-2018 IPR036259 MFS transporter superfamily MB46_02780 1bb545a3a769df1570e583c54f19ce92 477 Pfam PF07690 Major Facilitator Superfamily 69 430 1.9E-14 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MB46_02780 1bb545a3a769df1570e583c54f19ce92 477 Gene3D G3DSA:1.20.1250.20 248 475 1.4E-62 T 14-10-2018 MB46_02780 1bb545a3a769df1570e583c54f19ce92 477 Gene3D G3DSA:1.20.1250.20 25 247 2.1E-68 T 14-10-2018 MB46_00410 06f0c0b7d46528e74e3e1452766bb6f8 313 Gene3D G3DSA:3.40.50.1980 150 313 8.6E-42 T 14-10-2018 MB46_00410 06f0c0b7d46528e74e3e1452766bb6f8 313 SUPERFAMILY SSF53807 11 303 1.41E-41 T 14-10-2018 MB46_00410 06f0c0b7d46528e74e3e1452766bb6f8 313 Gene3D G3DSA:3.40.50.1980 6 147 2.1E-38 T 14-10-2018 MB46_00410 06f0c0b7d46528e74e3e1452766bb6f8 313 Pfam PF01497 Periplasmic binding protein 34 264 5.8E-23 T 14-10-2018 IPR002491 ABC transporter periplasmic binding domain MB46_06335 f93de95898a441e6775cb1f07505d070 553 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 88 435 2.6E-60 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain MB46_06335 f93de95898a441e6775cb1f07505d070 553 SUPERFAMILY SSF53850 58 528 3.98E-94 T 14-10-2018 MB46_06335 f93de95898a441e6775cb1f07505d070 553 Gene3D G3DSA:3.90.76.10 75 178 4.2E-146 T 14-10-2018 MB46_06335 f93de95898a441e6775cb1f07505d070 553 Gene3D G3DSA:3.40.190.10 59 533 4.2E-146 T 14-10-2018 MB46_06335 f93de95898a441e6775cb1f07505d070 553 PIRSF PIRSF002741 2 528 3.5E-69 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 MB46_06335 f93de95898a441e6775cb1f07505d070 553 Gene3D G3DSA:3.10.105.10 273 510 4.2E-146 T 14-10-2018 MB46_00600 7e5105d6575f9f70bcc94bdde6a3086f 363 SUPERFAMILY SSF53448 14 260 5.63E-39 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MB46_00600 7e5105d6575f9f70bcc94bdde6a3086f 363 Gene3D G3DSA:3.90.550.10 3 192 9.8E-28 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MB46_00600 7e5105d6575f9f70bcc94bdde6a3086f 363 Pfam PF00535 Glycosyl transferase family 2 17 179 3.5E-23 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MB46_01750 d381fa49995841e78906d59946b72985 365 Gene3D G3DSA:3.40.50.2300 149 355 1.0E-108 T 14-10-2018 MB46_01750 d381fa49995841e78906d59946b72985 365 SUPERFAMILY SSF53822 45 352 9.42E-57 T 14-10-2018 IPR028082 Periplasmic binding protein-like I MB46_01750 d381fa49995841e78906d59946b72985 365 Pfam PF13407 Periplasmic binding protein domain 47 318 3.4E-59 T 14-10-2018 IPR025997 Periplasmic binding protein MB46_01750 d381fa49995841e78906d59946b72985 365 Gene3D G3DSA:3.40.50.2300 47 340 1.0E-108 T 14-10-2018 MB46_01030 c9e64553740d5a16510ca29c72a31b40 219 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 32 214 1.9E-25 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_01030 c9e64553740d5a16510ca29c72a31b40 219 Gene3D G3DSA:1.10.3720.10 1 216 1.3E-53 T 14-10-2018 IPR035906 MetI-like superfamily MB46_01030 c9e64553740d5a16510ca29c72a31b40 219 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 12 108 1.6E-29 T 14-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 MB46_01030 c9e64553740d5a16510ca29c72a31b40 219 SUPERFAMILY SSF161098 12 214 4.58E-46 T 14-10-2018 IPR035906 MetI-like superfamily MB46_12945 a7f94027f6ff73e876ccc4f0bff15a7c 87 SMART SM00834 2 41 1.8E-10 T 14-10-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain MB46_12945 a7f94027f6ff73e876ccc4f0bff15a7c 87 Pfam PF09723 Zinc ribbon domain 2 39 1.2E-12 T 14-10-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain MB46_12945 a7f94027f6ff73e876ccc4f0bff15a7c 87 TIGRFAM TIGR02605 CxxC_CxxC_SSSS: putative regulatory protein, FmdB family 2 51 6.3E-17 T 14-10-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain MB46_12820 a15245593b53fa2f0acada32c1ad6d9f 229 SMART SM01007 16 200 3.0E-58 T 14-10-2018 IPR001303 Class II aldolase/adducin N-terminal MB46_12820 a15245593b53fa2f0acada32c1ad6d9f 229 Gene3D G3DSA:3.40.225.10 8 229 3.9E-61 T 14-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily MB46_12820 a15245593b53fa2f0acada32c1ad6d9f 229 SUPERFAMILY SSF53639 10 224 8.63E-58 T 14-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily MB46_12820 a15245593b53fa2f0acada32c1ad6d9f 229 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 16 198 1.6E-46 T 14-10-2018 IPR001303 Class II aldolase/adducin N-terminal MB46_08115 7e0fedddc050a844b8e6e4f9b4428edc 304 Pfam PF04960 Glutaminase 22 304 8.1E-100 T 14-10-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 MB46_08115 7e0fedddc050a844b8e6e4f9b4428edc 304 Gene3D G3DSA:3.40.710.10 1 304 5.7E-95 T 14-10-2018 MB46_08115 7e0fedddc050a844b8e6e4f9b4428edc 304 TIGRFAM TIGR03814 Gln_ase: glutaminase A 8 304 4.2E-114 T 14-10-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 MB46_08115 7e0fedddc050a844b8e6e4f9b4428edc 304 Hamap MF_00313 Glutaminase [glsA]. 4 304 42.313 T 14-10-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 MB46_08115 7e0fedddc050a844b8e6e4f9b4428edc 304 SUPERFAMILY SSF56601 3 304 1.13E-97 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like MB46_13515 ea5c8071975db1e5fc9aa5bac61a7986 235 ProSitePatterns PS01199 Ribosomal protein L1 signature. 121 139 - T 14-10-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MB46_13515 ea5c8071975db1e5fc9aa5bac61a7986 235 Gene3D G3DSA:3.40.50.790 68 159 3.4E-80 T 14-10-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich MB46_13515 ea5c8071975db1e5fc9aa5bac61a7986 235 Pfam PF00687 Ribosomal protein L1p/L10e family 34 220 8.1E-52 T 14-10-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein MB46_13515 ea5c8071975db1e5fc9aa5bac61a7986 235 Gene3D G3DSA:3.30.190.20 25 222 3.4E-80 T 14-10-2018 MB46_13515 ea5c8071975db1e5fc9aa5bac61a7986 235 PIRSF PIRSF002155 1 227 4.9E-73 T 14-10-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MB46_13515 ea5c8071975db1e5fc9aa5bac61a7986 235 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 3 227 2.8E-100 T 14-10-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 MB46_13515 ea5c8071975db1e5fc9aa5bac61a7986 235 SUPERFAMILY SSF56808 6 225 1.01E-80 T 14-10-2018 IPR023674 Ribosomal protein L1-like MB46_13515 ea5c8071975db1e5fc9aa5bac61a7986 235 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 2 229 41.919 T 14-10-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 MB46_05315 267c99bdab8895ca5db9300786f1cebf 446 Gene3D G3DSA:3.40.47.10 10 445 1.8E-101 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 MB46_05315 267c99bdab8895ca5db9300786f1cebf 446 Pfam PF00108 Thiolase, N-terminal domain 21 290 8.6E-50 T 14-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 MB46_05315 267c99bdab8895ca5db9300786f1cebf 446 SUPERFAMILY SSF53901 20 297 2.69E-55 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 MB46_05315 267c99bdab8895ca5db9300786f1cebf 446 SUPERFAMILY SSF53901 297 444 2.4E-27 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 MB46_05315 267c99bdab8895ca5db9300786f1cebf 446 PIRSF PIRSF000429 16 446 3.0E-100 T 14-10-2018 IPR002155 Thiolase GO:0016747 MB46_05315 267c99bdab8895ca5db9300786f1cebf 446 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 22 444 5.2E-113 T 14-10-2018 IPR002155 Thiolase GO:0016747 MB46_05315 267c99bdab8895ca5db9300786f1cebf 446 Pfam PF02803 Thiolase, C-terminal domain 317 444 2.6E-27 T 14-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 MB46_05950 1e7fcff6b36d3c1448ab39cc247daa15 453 SUPERFAMILY SSF53383 7 423 4.65E-121 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MB46_05950 1e7fcff6b36d3c1448ab39cc247daa15 453 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 201 215 - T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 MB46_05950 1e7fcff6b36d3c1448ab39cc247daa15 453 Gene3D G3DSA:3.90.1150.10 292 436 2.2E-44 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MB46_05950 1e7fcff6b36d3c1448ab39cc247daa15 453 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 10 423 9.9E-132 T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 MB46_05950 1e7fcff6b36d3c1448ab39cc247daa15 453 TIGRFAM TIGR01326 OAH_OAS_sulfhy: O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase 8 423 6.1E-176 T 14-10-2018 IPR006235 O-acetylhomoserine/O-acetylserine sulfhydrylase GO:0006520|GO:0016765 MB46_05950 1e7fcff6b36d3c1448ab39cc247daa15 453 Gene3D G3DSA:3.40.640.10 7 288 4.3E-100 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MB46_05950 1e7fcff6b36d3c1448ab39cc247daa15 453 PIRSF PIRSF001434 1 427 5.7E-122 T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 MB46_15515 0b1dffabf579f54e8cc2284a778d7f56 501 Pfam PF00512 His Kinase A (phospho-acceptor) domain 282 346 6.2E-19 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MB46_15515 0b1dffabf579f54e8cc2284a778d7f56 501 Gene3D G3DSA:3.30.565.10 350 501 4.5E-36 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MB46_15515 0b1dffabf579f54e8cc2284a778d7f56 501 Pfam PF00672 HAMP domain 210 268 1.3E-8 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MB46_15515 0b1dffabf579f54e8cc2284a778d7f56 501 SUPERFAMILY SSF55874 335 499 1.11E-36 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MB46_15515 0b1dffabf579f54e8cc2284a778d7f56 501 SUPERFAMILY SSF47384 267 347 1.45E-17 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MB46_15515 0b1dffabf579f54e8cc2284a778d7f56 501 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 391 499 2.2E-24 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MB46_15515 0b1dffabf579f54e8cc2284a778d7f56 501 Gene3D G3DSA:1.10.287.130 214 347 2.2E-24 T 14-10-2018 MB46_15515 0b1dffabf579f54e8cc2284a778d7f56 501 PRINTS PR00344 Bacterial sensor protein C-terminal signature 444 454 7.2E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MB46_15515 0b1dffabf579f54e8cc2284a778d7f56 501 PRINTS PR00344 Bacterial sensor protein C-terminal signature 463 481 7.2E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MB46_15515 0b1dffabf579f54e8cc2284a778d7f56 501 PRINTS PR00344 Bacterial sensor protein C-terminal signature 486 499 7.2E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MB46_15515 0b1dffabf579f54e8cc2284a778d7f56 501 PRINTS PR00344 Bacterial sensor protein C-terminal signature 426 440 7.2E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MB46_15515 0b1dffabf579f54e8cc2284a778d7f56 501 SMART SM00387 389 501 2.0E-31 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MB46_15515 0b1dffabf579f54e8cc2284a778d7f56 501 SMART SM00304 210 272 3.3E-7 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MB46_15515 0b1dffabf579f54e8cc2284a778d7f56 501 SMART SM00388 280 346 1.2E-21 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MB46_13360 bd14f00c05ed158cf146eff030d4fc0d 123 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 9 123 1.4E-47 T 14-10-2018 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_13360 bd14f00c05ed158cf146eff030d4fc0d 123 Gene3D G3DSA:3.30.420.100 8 122 7.2E-39 T 14-10-2018 MB46_13360 bd14f00c05ed158cf146eff030d4fc0d 123 SUPERFAMILY SSF53137 10 121 1.55E-47 T 14-10-2018 MB46_13360 bd14f00c05ed158cf146eff030d4fc0d 123 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 11 123 7.6E-39 T 14-10-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 MB46_13360 bd14f00c05ed158cf146eff030d4fc0d 123 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 9 123 27.46 T 14-10-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 MB46_13470 591f6175e95c3901fc468673430fc025 124 SUPERFAMILY SSF50249 2 123 1.11E-51 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold MB46_13470 591f6175e95c3901fc468673430fc025 124 Gene3D G3DSA:2.40.50.140 1 124 3.6E-61 T 14-10-2018 MB46_13470 591f6175e95c3901fc468673430fc025 124 PRINTS PR01034 Ribosomal protein S12 signature 110 122 2.1E-56 T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MB46_13470 591f6175e95c3901fc468673430fc025 124 PRINTS PR01034 Ribosomal protein S12 signature 42 57 2.1E-56 T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MB46_13470 591f6175e95c3901fc468673430fc025 124 PRINTS PR01034 Ribosomal protein S12 signature 27 42 2.1E-56 T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MB46_13470 591f6175e95c3901fc468673430fc025 124 PRINTS PR01034 Ribosomal protein S12 signature 58 77 2.1E-56 T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MB46_13470 591f6175e95c3901fc468673430fc025 124 PRINTS PR01034 Ribosomal protein S12 signature 77 94 2.1E-56 T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MB46_13470 591f6175e95c3901fc468673430fc025 124 PRINTS PR01034 Ribosomal protein S12 signature 94 110 2.1E-56 T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MB46_13470 591f6175e95c3901fc468673430fc025 124 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 2 123 8.3E-66 T 14-10-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_13470 591f6175e95c3901fc468673430fc025 124 ProSitePatterns PS00055 Ribosomal protein S12 signature. 43 50 - T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MB46_13470 591f6175e95c3901fc468673430fc025 124 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 123 39.348 T 14-10-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_13470 591f6175e95c3901fc468673430fc025 124 PIRSF PIRSF002133 1 124 4.2E-53 T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MB46_13470 591f6175e95c3901fc468673430fc025 124 Pfam PF00164 Ribosomal protein S12/S23 13 122 4.4E-42 T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MB46_19710 d9aab4f41b58e2fb8815d7156ad5cc08 199 SUPERFAMILY SSF53335 6 182 3.04E-35 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MB46_19710 d9aab4f41b58e2fb8815d7156ad5cc08 199 Gene3D G3DSA:3.40.50.150 3 198 3.5E-56 T 14-10-2018 MB46_19710 d9aab4f41b58e2fb8815d7156ad5cc08 199 Pfam PF13649 Methyltransferase domain 46 136 3.1E-18 T 14-10-2018 MB46_00885 1e354c9bfb1f768086a8197b8e3c3baa 357 Pfam PF02388 FemAB family 22 119 2.1E-6 T 14-10-2018 IPR003447 FemABX peptidyl transferase GO:0016755|GO:0044038 MB46_00885 1e354c9bfb1f768086a8197b8e3c3baa 357 Pfam PF02388 FemAB family 137 220 4.0E-5 T 14-10-2018 IPR003447 FemABX peptidyl transferase GO:0016755|GO:0044038 MB46_00885 1e354c9bfb1f768086a8197b8e3c3baa 357 Pfam PF02388 FemAB family 238 339 5.2E-13 T 14-10-2018 IPR003447 FemABX peptidyl transferase GO:0016755|GO:0044038 MB46_00885 1e354c9bfb1f768086a8197b8e3c3baa 357 SUPERFAMILY SSF55729 153 337 1.85E-24 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase MB46_00885 1e354c9bfb1f768086a8197b8e3c3baa 357 SUPERFAMILY SSF55729 6 155 1.43E-14 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase MB46_00885 1e354c9bfb1f768086a8197b8e3c3baa 357 Gene3D G3DSA:3.40.630.30 15 330 4.7E-64 T 14-10-2018 MB46_00885 1e354c9bfb1f768086a8197b8e3c3baa 357 Gene3D G3DSA:3.40.630.30 144 318 4.7E-64 T 14-10-2018 MB46_16845 0fd41fcec07143fc9917d59475556efa 93 SMART SM00411 3 92 4.9E-28 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MB46_16845 0fd41fcec07143fc9917d59475556efa 93 PRINTS PR01727 Prokaryotic integration host factor signature 60 73 1.4E-6 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MB46_16845 0fd41fcec07143fc9917d59475556efa 93 PRINTS PR01727 Prokaryotic integration host factor signature 76 90 1.4E-6 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MB46_16845 0fd41fcec07143fc9917d59475556efa 93 PRINTS PR01727 Prokaryotic integration host factor signature 42 57 1.4E-6 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MB46_16845 0fd41fcec07143fc9917d59475556efa 93 Gene3D G3DSA:4.10.520.10 3 93 1.5E-27 T 14-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 MB46_16845 0fd41fcec07143fc9917d59475556efa 93 SUPERFAMILY SSF47729 4 92 7.95E-24 T 14-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 MB46_16845 0fd41fcec07143fc9917d59475556efa 93 Pfam PF00216 Bacterial DNA-binding protein 4 92 4.2E-24 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MB46_15650 5f76016ac6a66dfcb326c7c7546156bc 339 SUPERFAMILY SSF47413 8 66 1.69E-17 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MB46_15650 5f76016ac6a66dfcb326c7c7546156bc 339 SMART SM00354 8 78 6.9E-27 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MB46_15650 5f76016ac6a66dfcb326c7c7546156bc 339 Gene3D G3DSA:3.40.50.2300 84 314 1.5E-62 T 14-10-2018 MB46_15650 5f76016ac6a66dfcb326c7c7546156bc 339 Pfam PF00356 Bacterial regulatory proteins, lacI family 10 55 2.3E-16 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MB46_15650 5f76016ac6a66dfcb326c7c7546156bc 339 ProSitePatterns PS00356 LacI-type HTH domain signature. 11 29 - T 14-10-2018 MB46_15650 5f76016ac6a66dfcb326c7c7546156bc 339 Gene3D G3DSA:1.10.260.40 1 66 1.2E-22 T 14-10-2018 MB46_15650 5f76016ac6a66dfcb326c7c7546156bc 339 Gene3D G3DSA:3.40.50.2300 166 293 1.5E-62 T 14-10-2018 MB46_15650 5f76016ac6a66dfcb326c7c7546156bc 339 Pfam PF13377 Periplasmic binding protein-like domain 175 333 7.0E-35 T 14-10-2018 MB46_15650 5f76016ac6a66dfcb326c7c7546156bc 339 SUPERFAMILY SSF53822 68 337 2.75E-54 T 14-10-2018 IPR028082 Periplasmic binding protein-like I MB46_17390 6074db547db4ead6f21c04910ce5f257 576 Gene3D G3DSA:1.10.150.20 342 483 2.3E-26 T 14-10-2018 MB46_17390 6074db547db4ead6f21c04910ce5f257 576 Gene3D G3DSA:3.30.70.370 303 565 2.3E-26 T 14-10-2018 MB46_17390 6074db547db4ead6f21c04910ce5f257 576 SMART SM00482 321 535 9.6E-10 T 14-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MB46_17390 6074db547db4ead6f21c04910ce5f257 576 Pfam PF00476 DNA polymerase family A 211 565 2.7E-32 T 14-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MB46_17390 6074db547db4ead6f21c04910ce5f257 576 SUPERFAMILY SSF56672 163 576 1.0E-65 T 14-10-2018 MB46_02365 5df4a4344e79a2f388bd513e5fc43a4e 328 Pfam PF01944 Stage II sporulation protein M 106 277 2.4E-34 T 14-10-2018 IPR002798 Stage II sporulation protein M-like MB46_03090 23dbbc0c02936809b47d251baa3bfc32 311 SUPERFAMILY SSF46785 2 87 3.1E-14 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_03090 23dbbc0c02936809b47d251baa3bfc32 311 SUPERFAMILY SSF53850 87 308 2.9E-21 T 14-10-2018 MB46_03090 23dbbc0c02936809b47d251baa3bfc32 311 Pfam PF03466 LysR substrate binding domain 87 305 7.2E-22 T 14-10-2018 IPR005119 LysR, substrate-binding MB46_03090 23dbbc0c02936809b47d251baa3bfc32 311 Gene3D G3DSA:3.40.190.10 91 289 3.1E-18 T 14-10-2018 MB46_03090 23dbbc0c02936809b47d251baa3bfc32 311 Gene3D G3DSA:1.10.10.10 1 88 1.9E-16 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_03090 23dbbc0c02936809b47d251baa3bfc32 311 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 4.5E-13 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MB46_03090 23dbbc0c02936809b47d251baa3bfc32 311 Gene3D G3DSA:3.40.190.10 177 279 3.1E-18 T 14-10-2018 MB46_18900 3d7d560cbfb2ec1a8d44f2e044e9b07a 297 SUPERFAMILY SSF161098 28 291 1.06E-65 T 14-10-2018 IPR035906 MetI-like superfamily MB46_18900 3d7d560cbfb2ec1a8d44f2e044e9b07a 297 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 286 1.1E-21 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_18900 3d7d560cbfb2ec1a8d44f2e044e9b07a 297 Gene3D G3DSA:1.10.3720.10 21 288 1.7E-63 T 14-10-2018 IPR035906 MetI-like superfamily MB46_06915 d592ddad6b9cfcbe97aed9c2308c91f5 182 Pfam PF00583 Acetyltransferase (GNAT) family 55 151 2.9E-14 T 14-10-2018 IPR000182 GNAT domain MB46_06915 d592ddad6b9cfcbe97aed9c2308c91f5 182 Gene3D G3DSA:3.40.630.30 2 162 2.2E-23 T 14-10-2018 MB46_06915 d592ddad6b9cfcbe97aed9c2308c91f5 182 SUPERFAMILY SSF55729 5 157 1.7E-25 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase MB46_09175 63dc76cba6afb51c47fd06312828d614 286 PRINTS PR00111 Alpha/beta hydrolase fold signature 108 121 1.4E-8 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MB46_09175 63dc76cba6afb51c47fd06312828d614 286 PRINTS PR00111 Alpha/beta hydrolase fold signature 230 244 1.4E-8 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MB46_09175 63dc76cba6afb51c47fd06312828d614 286 PRINTS PR00111 Alpha/beta hydrolase fold signature 65 80 1.4E-8 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MB46_09175 63dc76cba6afb51c47fd06312828d614 286 PRINTS PR00111 Alpha/beta hydrolase fold signature 122 135 1.4E-8 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MB46_09175 63dc76cba6afb51c47fd06312828d614 286 Pfam PF00561 alpha/beta hydrolase fold 47 270 1.3E-20 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MB46_09175 63dc76cba6afb51c47fd06312828d614 286 SUPERFAMILY SSF53474 19 285 5.0E-54 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_09175 63dc76cba6afb51c47fd06312828d614 286 Gene3D G3DSA:3.40.50.1820 5 285 3.8E-65 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_07720 5ddcff9f23b241f89ff05c6c9da5b636 521 SUPERFAMILY SSF48013 57 211 9.65E-34 T 14-10-2018 IPR035926 NusB-like superfamily MB46_07720 5ddcff9f23b241f89ff05c6c9da5b636 521 Gene3D G3DSA:1.10.940.10 54 193 2.0E-40 T 14-10-2018 IPR035926 NusB-like superfamily MB46_07720 5ddcff9f23b241f89ff05c6c9da5b636 521 Pfam PF01189 16S rRNA methyltransferase RsmB/F 316 518 1.4E-51 T 14-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 MB46_07720 5ddcff9f23b241f89ff05c6c9da5b636 521 Pfam PF01029 NusB family 57 179 1.9E-23 T 14-10-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 MB46_07720 5ddcff9f23b241f89ff05c6c9da5b636 521 Gene3D G3DSA:3.40.50.150 197 520 9.9E-62 T 14-10-2018 MB46_07720 5ddcff9f23b241f89ff05c6c9da5b636 521 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 320 330 3.6E-22 T 14-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase MB46_07720 5ddcff9f23b241f89ff05c6c9da5b636 521 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 438 454 3.6E-22 T 14-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase MB46_07720 5ddcff9f23b241f89ff05c6c9da5b636 521 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 283 297 3.6E-22 T 14-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase MB46_07720 5ddcff9f23b241f89ff05c6c9da5b636 521 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 388 400 3.6E-22 T 14-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase MB46_07720 5ddcff9f23b241f89ff05c6c9da5b636 521 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 503 520 3.6E-22 T 14-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase MB46_07720 5ddcff9f23b241f89ff05c6c9da5b636 521 SUPERFAMILY SSF53335 247 520 1.16E-49 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MB46_07720 5ddcff9f23b241f89ff05c6c9da5b636 521 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 387 398 - T 14-10-2018 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 MB46_15200 45457fb1e664a61a3af985b7294d768b 173 SUPERFAMILY SSF55729 1 144 2.16E-20 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase MB46_15200 45457fb1e664a61a3af985b7294d768b 173 Pfam PF13508 Acetyltransferase (GNAT) domain 63 139 7.5E-7 T 14-10-2018 IPR000182 GNAT domain MB46_15200 45457fb1e664a61a3af985b7294d768b 173 Gene3D G3DSA:3.40.630.30 5 160 2.2E-25 T 14-10-2018 MB46_12510 8e3eb1634fa9030b77b7b587ec45ba3c 107 Gene3D G3DSA:3.30.70.20 2 106 8.0E-46 T 14-10-2018 MB46_12510 8e3eb1634fa9030b77b7b587ec45ba3c 107 Pfam PF00037 4Fe-4S binding domain 34 56 1.2E-8 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MB46_12510 8e3eb1634fa9030b77b7b587ec45ba3c 107 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 40 51 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MB46_12510 8e3eb1634fa9030b77b7b587ec45ba3c 107 PRINTS PR00354 7Fe ferredoxin signature 35 52 3.6E-18 T 14-10-2018 IPR000813 7Fe ferredoxin GO:0009055 MB46_12510 8e3eb1634fa9030b77b7b587ec45ba3c 107 PRINTS PR00354 7Fe ferredoxin signature 9 19 3.6E-18 T 14-10-2018 IPR000813 7Fe ferredoxin GO:0009055 MB46_12510 8e3eb1634fa9030b77b7b587ec45ba3c 107 PRINTS PR00354 7Fe ferredoxin signature 19 29 3.6E-18 T 14-10-2018 IPR000813 7Fe ferredoxin GO:0009055 MB46_12510 8e3eb1634fa9030b77b7b587ec45ba3c 107 SUPERFAMILY SSF54862 3 85 2.33E-21 T 14-10-2018 MB46_14000 a9714ae252c33dc03e6322b0433fa8e3 126 SUPERFAMILY SSF52833 4 102 1.86E-28 T 14-10-2018 IPR036249 Thioredoxin-like superfamily MB46_14000 a9714ae252c33dc03e6322b0433fa8e3 126 Gene3D G3DSA:3.40.30.10 1 119 1.5E-26 T 14-10-2018 MB46_14000 a9714ae252c33dc03e6322b0433fa8e3 126 Pfam PF00085 Thioredoxin 4 101 1.0E-22 T 14-10-2018 IPR013766 Thioredoxin domain GO:0045454 MB46_14000 a9714ae252c33dc03e6322b0433fa8e3 126 PIRSF PIRSF000077 1 104 2.3E-23 T 14-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 MB46_14000 a9714ae252c33dc03e6322b0433fa8e3 126 PRINTS PR00421 Thioredoxin family signature 29 38 2.3E-6 T 14-10-2018 MB46_14000 a9714ae252c33dc03e6322b0433fa8e3 126 PRINTS PR00421 Thioredoxin family signature 68 79 2.3E-6 T 14-10-2018 MB46_14000 a9714ae252c33dc03e6322b0433fa8e3 126 PRINTS PR00421 Thioredoxin family signature 21 29 2.3E-6 T 14-10-2018 MB46_07555 322c2e57e06c6f00270ea0993577304f 305 Pfam PF01545 Cation efflux family 19 216 2.2E-16 T 14-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 MB46_07555 322c2e57e06c6f00270ea0993577304f 305 SUPERFAMILY SSF161111 13 217 1.57E-18 T 14-10-2018 IPR027469 Cation efflux transmembrane domain superfamily MB46_07555 322c2e57e06c6f00270ea0993577304f 305 Gene3D G3DSA:1.20.1510.10 13 216 3.3E-10 T 14-10-2018 IPR027469 Cation efflux transmembrane domain superfamily MB46_04780 f8eeec1e9d33ecfb11a0cf376d18a0d3 203 Gene3D G3DSA:1.20.1290.10 18 174 2.9E-26 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MB46_04780 f8eeec1e9d33ecfb11a0cf376d18a0d3 203 Pfam PF02627 Carboxymuconolactone decarboxylase family 41 117 2.8E-7 T 14-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 MB46_04780 f8eeec1e9d33ecfb11a0cf376d18a0d3 203 SUPERFAMILY SSF69118 1 174 1.68E-31 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MB46_12775 64d4348bfbfc5174c22e7e95fc2746ea 831 Gene3D G3DSA:1.10.10.10 764 830 1.6E-16 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_12775 64d4348bfbfc5174c22e7e95fc2746ea 831 Gene3D G3DSA:1.25.40.10 382 745 5.7E-13 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MB46_12775 64d4348bfbfc5174c22e7e95fc2746ea 831 SUPERFAMILY SSF52540 21 138 1.04E-5 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_12775 64d4348bfbfc5174c22e7e95fc2746ea 831 SUPERFAMILY SSF48452 406 495 1.99E-7 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MB46_12775 64d4348bfbfc5174c22e7e95fc2746ea 831 Pfam PF00196 Bacterial regulatory proteins, luxR family 769 823 1.6E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_12775 64d4348bfbfc5174c22e7e95fc2746ea 831 SUPERFAMILY SSF46894 761 830 4.76E-16 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MB46_12775 64d4348bfbfc5174c22e7e95fc2746ea 831 SMART SM00421 767 824 2.5E-14 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_00055 f650a4abac5daba3682627cd57b82bb3 304 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 106 296 6.0E-18 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_00055 f650a4abac5daba3682627cd57b82bb3 304 SUPERFAMILY SSF161098 30 304 2.15E-64 T 14-10-2018 IPR035906 MetI-like superfamily MB46_00055 f650a4abac5daba3682627cd57b82bb3 304 Gene3D G3DSA:1.10.3720.10 28 291 2.4E-61 T 14-10-2018 IPR035906 MetI-like superfamily MB46_05005 b7df2cef0e064a5caf65a908f1b7cc9a 589 SUPERFAMILY SSF90123 7 315 3.4E-71 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MB46_05005 b7df2cef0e064a5caf65a908f1b7cc9a 589 ProSitePatterns PS00211 ABC transporters family signature. 472 486 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_05005 b7df2cef0e064a5caf65a908f1b7cc9a 589 Gene3D G3DSA:3.40.50.300 323 573 5.4E-78 T 14-10-2018 MB46_05005 b7df2cef0e064a5caf65a908f1b7cc9a 589 Gene3D G3DSA:1.20.1560.10 2 316 3.4E-82 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MB46_05005 b7df2cef0e064a5caf65a908f1b7cc9a 589 SUPERFAMILY SSF52540 323 570 3.63E-79 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_05005 b7df2cef0e064a5caf65a908f1b7cc9a 589 Pfam PF00664 ABC transporter transmembrane region 17 288 6.6E-42 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 MB46_05005 b7df2cef0e064a5caf65a908f1b7cc9a 589 Pfam PF00005 ABC transporter 351 498 6.3E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_05005 b7df2cef0e064a5caf65a908f1b7cc9a 589 SMART SM00382 360 552 1.7E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_06930 de09cf9b97ce3c12a8520823e840bd2f 324 SUPERFAMILY SSF56317 3 299 1.09E-57 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily MB46_06930 de09cf9b97ce3c12a8520823e840bd2f 324 Gene3D G3DSA:3.60.110.10 3 308 3.4E-55 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily MB46_06930 de09cf9b97ce3c12a8520823e840bd2f 324 Pfam PF00795 Carbon-nitrogen hydrolase 5 280 1.3E-32 T 14-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 MB46_16390 b396d2a50534b5dca4634d1f06012c09 769 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 463 469 - T 14-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 MB46_16390 b396d2a50534b5dca4634d1f06012c09 769 Gene3D G3DSA:3.40.1110.10 472 592 6.7E-86 T 14-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 MB46_16390 b396d2a50534b5dca4634d1f06012c09 769 Pfam PF00702 haloacid dehalogenase-like hydrolase 457 676 3.1E-42 T 14-10-2018 MB46_16390 b396d2a50534b5dca4634d1f06012c09 769 Pfam PF00122 E1-E2 ATPase 263 440 4.1E-51 T 14-10-2018 MB46_16390 b396d2a50534b5dca4634d1f06012c09 769 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 234 745 3.4E-81 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MB46_16390 b396d2a50534b5dca4634d1f06012c09 769 SUPERFAMILY SSF81653 266 361 6.02E-24 T 14-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 MB46_16390 b396d2a50534b5dca4634d1f06012c09 769 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 173 765 8.3E-162 T 14-10-2018 MB46_16390 b396d2a50534b5dca4634d1f06012c09 769 SUPERFAMILY SSF56784 459 762 1.98E-54 T 14-10-2018 IPR036412 HAD-like superfamily MB46_16390 b396d2a50534b5dca4634d1f06012c09 769 Pfam PF00403 Heavy-metal-associated domain 20 78 5.1E-11 T 14-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 MB46_16390 b396d2a50534b5dca4634d1f06012c09 769 SUPERFAMILY SSF55008 13 84 1.83E-16 T 14-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 MB46_16390 b396d2a50534b5dca4634d1f06012c09 769 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 191 764 4.2E-178 T 14-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 MB46_16390 b396d2a50534b5dca4634d1f06012c09 769 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 461 475 5.4E-24 T 14-10-2018 MB46_16390 b396d2a50534b5dca4634d1f06012c09 769 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 662 681 5.4E-24 T 14-10-2018 MB46_16390 b396d2a50534b5dca4634d1f06012c09 769 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 585 596 5.4E-24 T 14-10-2018 MB46_16390 b396d2a50534b5dca4634d1f06012c09 769 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 311 325 5.4E-24 T 14-10-2018 MB46_16390 b396d2a50534b5dca4634d1f06012c09 769 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 607 617 5.4E-24 T 14-10-2018 MB46_16390 b396d2a50534b5dca4634d1f06012c09 769 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 685 697 5.4E-24 T 14-10-2018 MB46_16390 b396d2a50534b5dca4634d1f06012c09 769 SUPERFAMILY SSF81665 217 453 1.83E-14 T 14-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 MB46_16390 b396d2a50534b5dca4634d1f06012c09 769 PRINTS PR00943 Copper-transporting ATPase signature 32 46 6.5E-9 T 14-10-2018 MB46_16390 b396d2a50534b5dca4634d1f06012c09 769 PRINTS PR00943 Copper-transporting ATPase signature 639 656 6.5E-9 T 14-10-2018 MB46_16390 b396d2a50534b5dca4634d1f06012c09 769 PRINTS PR00943 Copper-transporting ATPase signature 696 710 6.5E-9 T 14-10-2018 MB46_16390 b396d2a50534b5dca4634d1f06012c09 769 PRINTS PR00943 Copper-transporting ATPase signature 384 398 6.5E-9 T 14-10-2018 MB46_16390 b396d2a50534b5dca4634d1f06012c09 769 PRINTS PR00943 Copper-transporting ATPase signature 444 459 6.5E-9 T 14-10-2018 MB46_16390 b396d2a50534b5dca4634d1f06012c09 769 ProSitePatterns PS01047 Heavy-metal-associated domain. 22 50 - T 14-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 MB46_16390 b396d2a50534b5dca4634d1f06012c09 769 Gene3D G3DSA:3.30.70.100 17 82 5.6E-18 T 14-10-2018 MB46_16390 b396d2a50534b5dca4634d1f06012c09 769 Gene3D G3DSA:3.40.50.1000 442 714 6.7E-86 T 14-10-2018 IPR023214 HAD superfamily MB46_16390 b396d2a50534b5dca4634d1f06012c09 769 Gene3D G3DSA:2.70.150.20 254 366 7.7E-35 T 14-10-2018 MB46_03340 7157dda9d4f747d3eb453bcf9a780280 360 Gene3D G3DSA:3.40.50.2000 59 162 1.4E-8 T 14-10-2018 MB46_03340 7157dda9d4f747d3eb453bcf9a780280 360 SUPERFAMILY SSF53756 19 347 4.26E-53 T 14-10-2018 MB46_03340 7157dda9d4f747d3eb453bcf9a780280 360 Pfam PF00534 Glycosyl transferases group 1 169 326 4.3E-27 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 MB46_03340 7157dda9d4f747d3eb453bcf9a780280 360 Gene3D G3DSA:3.40.50.2000 164 328 1.1E-36 T 14-10-2018 MB46_03340 7157dda9d4f747d3eb453bcf9a780280 360 Pfam PF13439 Glycosyltransferase Family 4 71 155 1.6E-7 T 14-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 MB46_09430 1a2a4b0ee9e17f151ff6443b6fad03f7 274 SMART SM00346 28 117 1.0E-15 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 MB46_09430 1a2a4b0ee9e17f151ff6443b6fad03f7 274 SUPERFAMILY SSF55781 93 271 7.19E-27 T 14-10-2018 MB46_09430 1a2a4b0ee9e17f151ff6443b6fad03f7 274 Gene3D G3DSA:3.30.450.40 102 274 5.7E-33 T 14-10-2018 IPR029016 GAF-like domain superfamily MB46_09430 1a2a4b0ee9e17f151ff6443b6fad03f7 274 Pfam PF09339 IclR helix-turn-helix domain 30 81 1.7E-11 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 MB46_09430 1a2a4b0ee9e17f151ff6443b6fad03f7 274 Pfam PF01614 Bacterial transcriptional regulator 145 264 7.1E-18 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal MB46_09430 1a2a4b0ee9e17f151ff6443b6fad03f7 274 SUPERFAMILY SSF46785 30 101 1.15E-11 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_09430 1a2a4b0ee9e17f151ff6443b6fad03f7 274 Gene3D G3DSA:1.10.10.10 24 100 7.4E-18 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_14080 bc3a716d0fbbedd1c2bcf2b5ea58db47 488 Gene3D G3DSA:2.40.180.10 6 487 3.5E-217 T 14-10-2018 IPR037060 Catalase core domain superfamily GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 MB46_14080 bc3a716d0fbbedd1c2bcf2b5ea58db47 488 PRINTS PR00067 Catalase signature 86 104 3.1E-72 T 14-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MB46_14080 bc3a716d0fbbedd1c2bcf2b5ea58db47 488 PRINTS PR00067 Catalase signature 291 318 3.1E-72 T 14-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MB46_14080 bc3a716d0fbbedd1c2bcf2b5ea58db47 488 PRINTS PR00067 Catalase signature 126 144 3.1E-72 T 14-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MB46_14080 bc3a716d0fbbedd1c2bcf2b5ea58db47 488 PRINTS PR00067 Catalase signature 107 124 3.1E-72 T 14-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MB46_14080 bc3a716d0fbbedd1c2bcf2b5ea58db47 488 PRINTS PR00067 Catalase signature 323 349 3.1E-72 T 14-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MB46_14080 bc3a716d0fbbedd1c2bcf2b5ea58db47 488 PRINTS PR00067 Catalase signature 23 46 3.1E-72 T 14-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MB46_14080 bc3a716d0fbbedd1c2bcf2b5ea58db47 488 SMART SM01060 10 394 4.2E-285 T 14-10-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MB46_14080 bc3a716d0fbbedd1c2bcf2b5ea58db47 488 PIRSF PIRSF038928 1 486 5.9E-218 T 14-10-2018 IPR024711 Catalase, mono-functional, haem-containing, clades 1 and 3 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MB46_14080 bc3a716d0fbbedd1c2bcf2b5ea58db47 488 Pfam PF00199 Catalase 10 390 9.1E-186 T 14-10-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MB46_14080 bc3a716d0fbbedd1c2bcf2b5ea58db47 488 SUPERFAMILY SSF56634 4 484 9.29E-203 T 14-10-2018 IPR020835 Catalase superfamily GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MB46_14080 bc3a716d0fbbedd1c2bcf2b5ea58db47 488 Pfam PF06628 Catalase-related immune-responsive 418 479 1.6E-16 T 14-10-2018 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MB46_14080 bc3a716d0fbbedd1c2bcf2b5ea58db47 488 ProSitePatterns PS00438 Catalase proximal active site signature. 46 62 - T 14-10-2018 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MB46_05230 bcae91a16bf44a7b4ab7063be885fd45 261 Gene3D G3DSA:3.40.50.300 1 258 2.9E-55 T 14-10-2018 MB46_05230 bcae91a16bf44a7b4ab7063be885fd45 261 Pfam PF00005 ABC transporter 20 170 1.3E-23 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_05230 bcae91a16bf44a7b4ab7063be885fd45 261 SMART SM00382 29 230 2.4E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_05230 bcae91a16bf44a7b4ab7063be885fd45 261 SUPERFAMILY SSF52540 5 241 3.79E-47 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_11920 614f3958a48ac3b999c6e11b0a8b0872 501 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 56 151 6.7E-15 T 14-10-2018 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 MB46_11920 614f3958a48ac3b999c6e11b0a8b0872 501 PRINTS PR00481 Cytosol aminopeptidase signature 284 305 5.1E-44 T 14-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 MB46_11920 614f3958a48ac3b999c6e11b0a8b0872 501 PRINTS PR00481 Cytosol aminopeptidase signature 343 363 5.1E-44 T 14-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 MB46_11920 614f3958a48ac3b999c6e11b0a8b0872 501 PRINTS PR00481 Cytosol aminopeptidase signature 371 386 5.1E-44 T 14-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 MB46_11920 614f3958a48ac3b999c6e11b0a8b0872 501 PRINTS PR00481 Cytosol aminopeptidase signature 261 278 5.1E-44 T 14-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 MB46_11920 614f3958a48ac3b999c6e11b0a8b0872 501 PRINTS PR00481 Cytosol aminopeptidase signature 321 342 5.1E-44 T 14-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 MB46_11920 614f3958a48ac3b999c6e11b0a8b0872 501 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 347 354 - T 14-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 MB46_11920 614f3958a48ac3b999c6e11b0a8b0872 501 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 12 499 30.708 T 14-10-2018 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 MB46_11920 614f3958a48ac3b999c6e11b0a8b0872 501 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 185 490 5.1E-111 T 14-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 MB46_11920 614f3958a48ac3b999c6e11b0a8b0872 501 SUPERFAMILY SSF52949 56 181 2.47E-16 T 14-10-2018 MB46_11920 614f3958a48ac3b999c6e11b0a8b0872 501 Gene3D G3DSA:3.40.220.10 6 169 2.1E-19 T 14-10-2018 MB46_11920 614f3958a48ac3b999c6e11b0a8b0872 501 Gene3D G3DSA:3.40.630.10 170 500 6.6E-120 T 14-10-2018 MB46_11920 614f3958a48ac3b999c6e11b0a8b0872 501 SUPERFAMILY SSF53187 180 497 8.63E-105 T 14-10-2018 MB46_11780 8fe924114caf7fd0e086cdbb863c1594 322 Gene3D G3DSA:3.40.50.620 2 194 2.9E-25 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MB46_11780 8fe924114caf7fd0e086cdbb863c1594 322 SUPERFAMILY SSF52402 3 183 4.33E-27 T 14-10-2018 MB46_11780 8fe924114caf7fd0e086cdbb863c1594 322 Pfam PF01012 Electron transfer flavoprotein domain 11 177 1.1E-22 T 14-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 MB46_11780 8fe924114caf7fd0e086cdbb863c1594 322 Gene3D G3DSA:3.40.50.1220 195 322 2.5E-50 T 14-10-2018 MB46_11780 8fe924114caf7fd0e086cdbb863c1594 322 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 200 280 4.4E-31 T 14-10-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 MB46_11780 8fe924114caf7fd0e086cdbb863c1594 322 SUPERFAMILY SSF52467 199 316 2.29E-41 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily MB46_11780 8fe924114caf7fd0e086cdbb863c1594 322 PIRSF PIRSF000089 1 322 1.0E-81 T 14-10-2018 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 MB46_11780 8fe924114caf7fd0e086cdbb863c1594 322 SMART SM00893 5 187 6.8E-11 T 14-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 MB46_19835 0457ed882e94157dd5cf59dedffe36a9 298 Gene3D G3DSA:3.40.50.720 122 249 3.5E-58 T 14-10-2018 MB46_19835 0457ed882e94157dd5cf59dedffe36a9 298 SUPERFAMILY SSF51735 111 237 6.3E-19 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_19835 0457ed882e94157dd5cf59dedffe36a9 298 Gene3D G3DSA:3.90.180.10 9 295 3.5E-58 T 14-10-2018 MB46_19835 0457ed882e94157dd5cf59dedffe36a9 298 SUPERFAMILY SSF50129 1 138 3.35E-25 T 14-10-2018 IPR011032 GroES-like superfamily MB46_19835 0457ed882e94157dd5cf59dedffe36a9 298 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 88 1.2E-7 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MB46_19835 0457ed882e94157dd5cf59dedffe36a9 298 SMART SM00829 10 296 2.1E-9 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MB46_19835 0457ed882e94157dd5cf59dedffe36a9 298 Pfam PF13602 Zinc-binding dehydrogenase 194 296 1.1E-7 T 14-10-2018 MB46_15670 c7e616657bfff6a0744569dbd79d7077 410 Gene3D G3DSA:3.30.565.10 276 403 4.1E-21 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MB46_15670 c7e616657bfff6a0744569dbd79d7077 410 SUPERFAMILY SSF55874 282 404 1.42E-6 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MB46_15670 c7e616657bfff6a0744569dbd79d7077 410 Pfam PF07730 Histidine kinase 198 260 9.4E-13 T 14-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 MB46_10590 80a26aa2129893b5aa211a0651044726 291 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 15 285 6.9E-87 T 14-10-2018 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 MB46_10590 80a26aa2129893b5aa211a0651044726 291 Gene3D G3DSA:3.90.1170.20 18 283 7.2E-96 T 14-10-2018 IPR037128 Quinolinate phosphoribosyl transferase, N-terminal domain superfamily GO:0016763 Reactome: R-HSA-196807 MB46_10590 80a26aa2129893b5aa211a0651044726 291 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 24 112 7.6E-22 T 14-10-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 MB46_10590 80a26aa2129893b5aa211a0651044726 291 SUPERFAMILY SSF54675 4 112 4.71E-26 T 14-10-2018 MB46_10590 80a26aa2129893b5aa211a0651044726 291 SUPERFAMILY SSF51690 114 285 1.02E-51 T 14-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 MB46_10590 80a26aa2129893b5aa211a0651044726 291 Gene3D G3DSA:3.20.20.70 128 275 7.2E-96 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MB46_10590 80a26aa2129893b5aa211a0651044726 291 PIRSF PIRSF006250 7 288 2.4E-80 T 14-10-2018 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 MB46_10590 80a26aa2129893b5aa211a0651044726 291 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 114 284 4.2E-54 T 14-10-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 Reactome: R-HSA-196807 MB46_00570 5857c1519ffae99c9ad9b61885ccc2ef 384 TIGRFAM TIGR02050 gshA_cyan_rel: carboxylate-amine ligase, YbdK family 3 284 4.5E-66 T 14-10-2018 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 MB46_00570 5857c1519ffae99c9ad9b61885ccc2ef 384 Gene3D G3DSA:3.30.590.20 1 352 1.2E-94 T 14-10-2018 MB46_00570 5857c1519ffae99c9ad9b61885ccc2ef 384 Hamap MF_01609 Glutamate--cysteine ligase [gshA]. 1 384 60.302 T 14-10-2018 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 MB46_00570 5857c1519ffae99c9ad9b61885ccc2ef 384 SUPERFAMILY SSF55931 1 345 1.47E-75 T 14-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 MB46_00570 5857c1519ffae99c9ad9b61885ccc2ef 384 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 4 279 1.5E-38 T 14-10-2018 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 MB46_06205 97a91eddc53477107442ba5c0d4befae 337 Pfam PF00356 Bacterial regulatory proteins, lacI family 2 44 7.1E-14 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MB46_06205 97a91eddc53477107442ba5c0d4befae 337 SUPERFAMILY SSF53822 57 321 3.3E-60 T 14-10-2018 IPR028082 Periplasmic binding protein-like I MB46_06205 97a91eddc53477107442ba5c0d4befae 337 Gene3D G3DSA:1.10.260.40 1 54 1.1E-20 T 14-10-2018 MB46_06205 97a91eddc53477107442ba5c0d4befae 337 Gene3D G3DSA:3.40.50.2300 73 315 5.3E-73 T 14-10-2018 MB46_06205 97a91eddc53477107442ba5c0d4befae 337 SUPERFAMILY SSF47413 2 54 2.2E-15 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MB46_06205 97a91eddc53477107442ba5c0d4befae 337 Gene3D G3DSA:3.40.50.2300 157 318 5.3E-73 T 14-10-2018 MB46_06205 97a91eddc53477107442ba5c0d4befae 337 Pfam PF13377 Periplasmic binding protein-like domain 166 324 1.7E-35 T 14-10-2018 MB46_06205 97a91eddc53477107442ba5c0d4befae 337 SMART SM00354 2 67 5.7E-18 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MB46_13980 34a53913947a31c9939275b7853997b6 574 Gene3D G3DSA:3.40.50.10440 13 178 4.5E-48 T 14-10-2018 MB46_13980 34a53913947a31c9939275b7853997b6 574 Pfam PF02733 Dak1 domain 41 323 2.3E-100 T 14-10-2018 IPR004006 DhaK domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 MB46_13980 34a53913947a31c9939275b7853997b6 574 SUPERFAMILY SSF101473 367 566 1.03E-40 T 14-10-2018 IPR036117 DhaL domain superfamily GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 MB46_13980 34a53913947a31c9939275b7853997b6 574 Pfam PF02734 DAK2 domain 390 565 5.2E-41 T 14-10-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 MB46_13980 34a53913947a31c9939275b7853997b6 574 Gene3D G3DSA:1.25.40.340 357 567 5.4E-46 T 14-10-2018 IPR036117 DhaL domain superfamily GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 MB46_13980 34a53913947a31c9939275b7853997b6 574 SMART SM01120 389 566 1.0E-43 T 14-10-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 MB46_13980 34a53913947a31c9939275b7853997b6 574 SUPERFAMILY SSF82549 1 325 4.97E-97 T 14-10-2018 MB46_13980 34a53913947a31c9939275b7853997b6 574 Gene3D G3DSA:3.30.1180.20 180 324 8.6E-41 T 14-10-2018 MB46_07925 42f42e0d9d97ef11eb513955e2b31272 162 Hamap MF_00116 Deoxyuridine 5'-triphosphate nucleotidohydrolase [dut]. 15 157 31.077 T 14-10-2018 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|KEGG: 00983+3.6.1.23 MB46_07925 42f42e0d9d97ef11eb513955e2b31272 162 TIGRFAM TIGR00576 dut: dUTP diphosphatase 20 156 2.0E-47 T 14-10-2018 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|KEGG: 00983+3.6.1.23 MB46_07925 42f42e0d9d97ef11eb513955e2b31272 162 Pfam PF00692 dUTPase 29 156 2.1E-29 T 14-10-2018 IPR029054 dUTPase-like MB46_07925 42f42e0d9d97ef11eb513955e2b31272 162 SUPERFAMILY SSF51283 17 156 2.22E-47 T 14-10-2018 IPR036157 dUTPase-like superfamily MB46_07925 42f42e0d9d97ef11eb513955e2b31272 162 Gene3D G3DSA:2.70.40.10 6 158 7.6E-51 T 14-10-2018 IPR036157 dUTPase-like superfamily MB46_17015 fcdf0de0d76ecf020ba668bea0f62645 403 SUPERFAMILY SSF53383 39 401 1.03E-106 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MB46_17015 fcdf0de0d76ecf020ba668bea0f62645 403 Hamap MF_02056 O-succinylhomoserine sulfhydrylase [metZ]. 15 401 51.978 T 14-10-2018 IPR006234 O-succinylhomoserine sulfhydrylase GO:0071268 MB46_17015 fcdf0de0d76ecf020ba668bea0f62645 403 TIGRFAM TIGR01325 O_suc_HS_sulf: O-succinylhomoserine sulfhydrylase 14 400 2.5E-179 T 14-10-2018 IPR006234 O-succinylhomoserine sulfhydrylase GO:0071268 MB46_17015 fcdf0de0d76ecf020ba668bea0f62645 403 Gene3D G3DSA:3.90.1150.10 264 401 4.2E-46 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MB46_17015 fcdf0de0d76ecf020ba668bea0f62645 403 Gene3D G3DSA:3.40.640.10 12 263 1.3E-77 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MB46_17015 fcdf0de0d76ecf020ba668bea0f62645 403 PIRSF PIRSF001434 2 403 4.4E-113 T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 MB46_17015 fcdf0de0d76ecf020ba668bea0f62645 403 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 14 400 5.2E-123 T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 MB46_00105 e39fd04e8a7cf04888874771bd01a344 376 Gene3D G3DSA:1.10.443.10 157 343 6.5E-30 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 MB46_00105 e39fd04e8a7cf04888874771bd01a344 376 Pfam PF00589 Phage integrase family 176 333 7.0E-10 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MB46_00105 e39fd04e8a7cf04888874771bd01a344 376 Gene3D G3DSA:1.10.150.130 34 140 9.3E-15 T 14-10-2018 IPR010998 Integrase/recombinase, N-terminal MB46_00105 e39fd04e8a7cf04888874771bd01a344 376 SUPERFAMILY SSF56349 38 332 2.38E-44 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MB46_02480 42c88c0ee43e861dd4243974757fcc27 902 Pfam PF00196 Bacterial regulatory proteins, luxR family 839 890 2.3E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_02480 42c88c0ee43e861dd4243974757fcc27 902 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 870 882 7.3E-9 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_02480 42c88c0ee43e861dd4243974757fcc27 902 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 854 870 7.3E-9 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_02480 42c88c0ee43e861dd4243974757fcc27 902 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 840 854 7.3E-9 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_02480 42c88c0ee43e861dd4243974757fcc27 902 Gene3D G3DSA:1.10.10.10 773 902 1.3E-16 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_02480 42c88c0ee43e861dd4243974757fcc27 902 SUPERFAMILY SSF46894 835 894 1.97E-14 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MB46_02480 42c88c0ee43e861dd4243974757fcc27 902 SMART SM00382 39 183 1.4E-4 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_02480 42c88c0ee43e861dd4243974757fcc27 902 Gene3D G3DSA:3.40.50.300 29 181 4.5E-10 T 14-10-2018 MB46_02480 42c88c0ee43e861dd4243974757fcc27 902 Pfam PF13191 AAA ATPase domain 12 149 1.1E-9 T 14-10-2018 MB46_02480 42c88c0ee43e861dd4243974757fcc27 902 SMART SM00421 837 894 4.8E-14 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_02480 42c88c0ee43e861dd4243974757fcc27 902 SUPERFAMILY SSF52540 11 224 2.88E-16 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_16045 2dc6d0f04c56c7f304905d7b10fd965a 108 PRINTS PR00421 Thioredoxin family signature 71 82 8.0E-7 T 14-10-2018 MB46_16045 2dc6d0f04c56c7f304905d7b10fd965a 108 PRINTS PR00421 Thioredoxin family signature 23 31 8.0E-7 T 14-10-2018 MB46_16045 2dc6d0f04c56c7f304905d7b10fd965a 108 PRINTS PR00421 Thioredoxin family signature 31 40 8.0E-7 T 14-10-2018 MB46_16045 2dc6d0f04c56c7f304905d7b10fd965a 108 Pfam PF00085 Thioredoxin 6 101 1.6E-29 T 14-10-2018 IPR013766 Thioredoxin domain GO:0045454 MB46_16045 2dc6d0f04c56c7f304905d7b10fd965a 108 Gene3D G3DSA:3.40.30.10 1 107 5.7E-35 T 14-10-2018 MB46_16045 2dc6d0f04c56c7f304905d7b10fd965a 108 PIRSF PIRSF000077 1 107 1.1E-38 T 14-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 MB46_16045 2dc6d0f04c56c7f304905d7b10fd965a 108 TIGRFAM TIGR01068 thioredoxin: thioredoxin 8 105 1.9E-35 T 14-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 MB46_16045 2dc6d0f04c56c7f304905d7b10fd965a 108 ProSitePatterns PS00194 Thioredoxin family active site. 24 42 - T 14-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 MB46_16045 2dc6d0f04c56c7f304905d7b10fd965a 108 SUPERFAMILY SSF52833 4 107 1.86E-36 T 14-10-2018 IPR036249 Thioredoxin-like superfamily MB46_15750 e391457ebc3ed6e28c4d5ed5f67fa3bd 133 ProSitePatterns PS00519 AsnC-type HTH domain signature. 2 28 - T 14-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site MB46_15750 e391457ebc3ed6e28c4d5ed5f67fa3bd 133 SMART SM00344 1 93 3.0E-17 T 14-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 MB46_15750 e391457ebc3ed6e28c4d5ed5f67fa3bd 133 Gene3D G3DSA:1.10.10.10 1 36 1.2E-9 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_15750 e391457ebc3ed6e28c4d5ed5f67fa3bd 133 SUPERFAMILY SSF46785 2 43 1.08E-8 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_15750 e391457ebc3ed6e28c4d5ed5f67fa3bd 133 SUPERFAMILY SSF54909 45 133 6.3E-16 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel MB46_15750 e391457ebc3ed6e28c4d5ed5f67fa3bd 133 Pfam PF13412 Winged helix-turn-helix DNA-binding 1 30 3.0E-6 T 14-10-2018 MB46_15750 e391457ebc3ed6e28c4d5ed5f67fa3bd 133 Pfam PF01037 Lrp/AsnC ligand binding domain 51 123 2.0E-17 T 14-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain MB46_15750 e391457ebc3ed6e28c4d5ed5f67fa3bd 133 Gene3D G3DSA:3.30.70.920 37 120 5.6E-19 T 14-10-2018 MB46_01025 feab9f54a86f3e28fac512a3794d0c54 269 SUPERFAMILY SSF52540 7 261 7.41E-70 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_01025 feab9f54a86f3e28fac512a3794d0c54 269 SMART SM00382 32 239 1.5E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_01025 feab9f54a86f3e28fac512a3794d0c54 269 PIRSF PIRSF039085 4 267 2.4E-100 T 14-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 MB46_01025 feab9f54a86f3e28fac512a3794d0c54 269 Pfam PF00005 ABC transporter 23 191 1.1E-31 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_01025 feab9f54a86f3e28fac512a3794d0c54 269 Gene3D G3DSA:3.40.50.300 4 268 3.7E-75 T 14-10-2018 MB46_01025 feab9f54a86f3e28fac512a3794d0c54 269 ProSitePatterns PS00211 ABC transporters family signature. 163 177 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_15590 5c9451ecf6d29045c50f5c56ab9de33b 312 Pfam PF00800 Prephenate dehydratase 13 191 7.0E-46 T 14-10-2018 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 MB46_15590 5c9451ecf6d29045c50f5c56ab9de33b 312 PIRSF PIRSF001500 2 287 1.2E-53 T 14-10-2018 IPR008242 Bifunctional P-protein, chorismate mutase/prephenate dehydratase GO:0004106|GO:0004664|GO:0005737|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 MB46_15590 5c9451ecf6d29045c50f5c56ab9de33b 312 ProSitePatterns PS00858 Prephenate dehydratase signature 2. 232 239 - T 14-10-2018 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 MB46_15590 5c9451ecf6d29045c50f5c56ab9de33b 312 Gene3D G3DSA:3.40.190.10 99 180 2.4E-26 T 14-10-2018 MB46_15590 5c9451ecf6d29045c50f5c56ab9de33b 312 SUPERFAMILY SSF55021 186 284 2.49E-23 T 14-10-2018 MB46_15590 5c9451ecf6d29045c50f5c56ab9de33b 312 Gene3D G3DSA:3.40.190.10 5 98 1.3E-27 T 14-10-2018 MB46_15590 5c9451ecf6d29045c50f5c56ab9de33b 312 SUPERFAMILY SSF53850 12 198 3.15E-44 T 14-10-2018 MB46_15590 5c9451ecf6d29045c50f5c56ab9de33b 312 Gene3D G3DSA:3.30.70.260 194 291 2.1E-34 T 14-10-2018 MB46_15590 5c9451ecf6d29045c50f5c56ab9de33b 312 Pfam PF01842 ACT domain 212 269 1.7E-6 T 14-10-2018 IPR002912 ACT domain MB46_05875 8e2610126db2a6a7feb36c28a78e32f6 342 Pfam PF13377 Periplasmic binding protein-like domain 173 338 5.1E-26 T 14-10-2018 MB46_05875 8e2610126db2a6a7feb36c28a78e32f6 342 Gene3D G3DSA:3.40.50.2300 164 296 1.0E-57 T 14-10-2018 MB46_05875 8e2610126db2a6a7feb36c28a78e32f6 342 SUPERFAMILY SSF47413 5 64 7.96E-13 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MB46_05875 8e2610126db2a6a7feb36c28a78e32f6 342 SMART SM00354 6 76 8.6E-17 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MB46_05875 8e2610126db2a6a7feb36c28a78e32f6 342 SUPERFAMILY SSF53822 66 339 1.33E-52 T 14-10-2018 IPR028082 Periplasmic binding protein-like I MB46_05875 8e2610126db2a6a7feb36c28a78e32f6 342 Pfam PF00356 Bacterial regulatory proteins, lacI family 8 51 2.6E-11 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MB46_05875 8e2610126db2a6a7feb36c28a78e32f6 342 Gene3D G3DSA:1.10.260.40 3 63 4.5E-16 T 14-10-2018 MB46_05875 8e2610126db2a6a7feb36c28a78e32f6 342 Gene3D G3DSA:3.40.50.2300 69 315 1.0E-57 T 14-10-2018 MB46_04860 cb78ddca6e8b3058b0d5007d4ac291ed 377 Gene3D G3DSA:3.30.360.10 131 376 9.4E-59 T 14-10-2018 MB46_04860 cb78ddca6e8b3058b0d5007d4ac291ed 377 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 40 127 4.7E-11 T 14-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 MB46_04860 cb78ddca6e8b3058b0d5007d4ac291ed 377 Gene3D G3DSA:3.40.50.720 1 130 1.1E-27 T 14-10-2018 MB46_04860 cb78ddca6e8b3058b0d5007d4ac291ed 377 SUPERFAMILY SSF55347 136 335 1.59E-26 T 14-10-2018 MB46_04860 cb78ddca6e8b3058b0d5007d4ac291ed 377 SUPERFAMILY SSF51735 40 163 1.66E-31 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_00720 70dcd42c2af20ec8e34c12a2b594881a 722 PIRSF PIRSF005536 11 712 9.8E-173 T 14-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 MB46_00720 70dcd42c2af20ec8e34c12a2b594881a 722 Pfam PF16875 Glycosyl hydrolase family 36 N-terminal domain 30 259 1.1E-44 T 14-10-2018 IPR031704 Glycosyl hydrolase family 36, N-terminal KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 MB46_00720 70dcd42c2af20ec8e34c12a2b594881a 722 ProSitePatterns PS00512 Alpha-galactosidase signature. 330 346 - T 14-10-2018 IPR000111 Glycoside hydrolase family 27/36, conserved site GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 MB46_00720 70dcd42c2af20ec8e34c12a2b594881a 722 SUPERFAMILY SSF51445 299 629 8.66E-94 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily MB46_00720 70dcd42c2af20ec8e34c12a2b594881a 722 Pfam PF02065 Melibiase 264 602 1.7E-116 T 14-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 MB46_00720 70dcd42c2af20ec8e34c12a2b594881a 722 Pfam PF16874 Glycosyl hydrolase family 36 C-terminal domain 617 709 9.8E-8 T 14-10-2018 IPR031705 Glycosyl hydrolase family 36, C-terminal KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 MB46_00720 70dcd42c2af20ec8e34c12a2b594881a 722 Gene3D G3DSA:3.20.20.70 282 599 4.1E-122 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MB46_00720 70dcd42c2af20ec8e34c12a2b594881a 722 PRINTS PR00743 Glycosyl hydrolase family 36 signature 301 315 3.5E-39 T 14-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 MB46_00720 70dcd42c2af20ec8e34c12a2b594881a 722 PRINTS PR00743 Glycosyl hydrolase family 36 signature 437 452 3.5E-39 T 14-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 MB46_00720 70dcd42c2af20ec8e34c12a2b594881a 722 PRINTS PR00743 Glycosyl hydrolase family 36 signature 329 344 3.5E-39 T 14-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 MB46_00720 70dcd42c2af20ec8e34c12a2b594881a 722 PRINTS PR00743 Glycosyl hydrolase family 36 signature 379 401 3.5E-39 T 14-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 MB46_00720 70dcd42c2af20ec8e34c12a2b594881a 722 PRINTS PR00743 Glycosyl hydrolase family 36 signature 487 503 3.5E-39 T 14-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 MB46_00720 70dcd42c2af20ec8e34c12a2b594881a 722 PRINTS PR00743 Glycosyl hydrolase family 36 signature 512 528 3.5E-39 T 14-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 MB46_00720 70dcd42c2af20ec8e34c12a2b594881a 722 PRINTS PR00743 Glycosyl hydrolase family 36 signature 216 231 3.5E-39 T 14-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 MB46_00720 70dcd42c2af20ec8e34c12a2b594881a 722 Gene3D G3DSA:2.70.98.60 10 281 3.0E-32 T 14-10-2018 IPR038417 Alpha-galactosidase, N-terminal domain superfamily KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 MB46_12735 99df2971a954ddc83fa03a09a474bb7b 624 Pfam PF03583 Secretory lipase 351 618 3.1E-25 T 14-10-2018 IPR005152 Lipase, secreted GO:0004806|GO:0016042 MB46_12735 99df2971a954ddc83fa03a09a474bb7b 624 Gene3D G3DSA:1.10.260.130 446 537 2.5E-78 T 14-10-2018 MB46_12735 99df2971a954ddc83fa03a09a474bb7b 624 Gene3D G3DSA:3.40.50.1820 252 610 2.5E-78 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_12735 99df2971a954ddc83fa03a09a474bb7b 624 SUPERFAMILY SSF53474 297 611 7.83E-24 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_12735 99df2971a954ddc83fa03a09a474bb7b 624 Pfam PF03729 Short repeat of unknown function (DUF308) 148 192 4.2E-5 T 14-10-2018 IPR005325 Protein of unknown function DUF308, membrane MB46_12735 99df2971a954ddc83fa03a09a474bb7b 624 Pfam PF03729 Short repeat of unknown function (DUF308) 91 158 2.1E-4 T 14-10-2018 IPR005325 Protein of unknown function DUF308, membrane MB46_12735 99df2971a954ddc83fa03a09a474bb7b 624 Pfam PF03729 Short repeat of unknown function (DUF308) 37 78 0.0018 T 14-10-2018 IPR005325 Protein of unknown function DUF308, membrane MB46_00555 7eea36e9652f5ae5061900c76e4db949 358 SUPERFAMILY SSF51395 2 355 5.27E-110 T 14-10-2018 MB46_00555 7eea36e9652f5ae5061900c76e4db949 358 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 6 334 2.1E-82 T 14-10-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 MB46_00555 7eea36e9652f5ae5061900c76e4db949 358 Gene3D G3DSA:3.20.20.70 3 358 1.6E-125 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MB46_10205 b0362374e754e5860989453b54d430b5 412 Gene3D G3DSA:3.40.190.10 26 412 6.5E-71 T 14-10-2018 MB46_10205 b0362374e754e5860989453b54d430b5 412 Pfam PF01547 Bacterial extracellular solute-binding protein 38 326 7.0E-29 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein MB46_10205 b0362374e754e5860989453b54d430b5 412 SUPERFAMILY SSF53850 33 409 1.25E-60 T 14-10-2018 MB46_13060 73b9670c29033a549ecca3354192ba73 251 SUPERFAMILY SSF52540 2 226 4.07E-60 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_13060 73b9670c29033a549ecca3354192ba73 251 SMART SM00382 26 213 2.1E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_13060 73b9670c29033a549ecca3354192ba73 251 Gene3D G3DSA:3.40.50.300 1 244 1.3E-66 T 14-10-2018 MB46_13060 73b9670c29033a549ecca3354192ba73 251 Pfam PF00005 ABC transporter 19 164 2.2E-26 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_00040 d65c86698a0792aaa4eddc13550715a0 587 Gene3D G3DSA:3.90.400.10 141 218 1.3E-141 T 14-10-2018 MB46_00040 d65c86698a0792aaa4eddc13550715a0 587 Pfam PF00128 Alpha amylase, catalytic domain 64 431 5.0E-75 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MB46_00040 d65c86698a0792aaa4eddc13550715a0 587 SMART SM00642 49 458 4.8E-107 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MB46_00040 d65c86698a0792aaa4eddc13550715a0 587 SUPERFAMILY SSF51445 39 519 1.63E-117 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily MB46_00040 d65c86698a0792aaa4eddc13550715a0 587 Gene3D G3DSA:3.20.20.80 41 517 1.3E-141 T 14-10-2018 MB46_05045 988dc4c2bfb79fa198fae6a49facaf0f 334 Pfam PF01933 Uncharacterised protein family UPF0052 24 285 1.6E-60 T 14-10-2018 IPR002882 LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 MB46_05045 988dc4c2bfb79fa198fae6a49facaf0f 334 TIGRFAM TIGR01826 CofD_related: conserved hypothetical protein 24 287 1.6E-76 T 14-10-2018 IPR010119 Gluconeogenesis factor MB46_05045 988dc4c2bfb79fa198fae6a49facaf0f 334 Gene3D G3DSA:3.40.50.12300 19 328 9.5E-88 T 14-10-2018 IPR038136 Gluconeogenesis factor superfamily MB46_05045 988dc4c2bfb79fa198fae6a49facaf0f 334 Hamap MF_00973 Gluconeogenesis factor. 20 330 29.008 T 14-10-2018 IPR010119 Gluconeogenesis factor MB46_05045 988dc4c2bfb79fa198fae6a49facaf0f 334 SUPERFAMILY SSF142338 21 324 3.92E-76 T 14-10-2018 MB46_10215 d123106edbd1c84ba70ef03d392cd44b 341 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 184 327 4.2E-60 T 14-10-2018 IPR000506 Ketol-acid reductoisomerase, C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 MB46_10215 d123106edbd1c84ba70ef03d392cd44b 341 Gene3D G3DSA:1.10.3730.40 183 336 1.9E-65 T 14-10-2018 MB46_10215 d123106edbd1c84ba70ef03d392cd44b 341 Gene3D G3DSA:3.40.50.720 1 182 1.8E-77 T 14-10-2018 MB46_10215 d123106edbd1c84ba70ef03d392cd44b 341 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 15 327 1.9E-127 T 14-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 MB46_10215 d123106edbd1c84ba70ef03d392cd44b 341 SUPERFAMILY SSF48179 184 332 1.87E-65 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MB46_10215 d123106edbd1c84ba70ef03d392cd44b 341 Hamap MF_00435 Ketol-acid reductoisomerase (NADP(+)) [ilvC]. 2 329 44.826 T 14-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 MB46_10215 d123106edbd1c84ba70ef03d392cd44b 341 SUPERFAMILY SSF51735 3 183 1.26E-71 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_10215 d123106edbd1c84ba70ef03d392cd44b 341 PIRSF PIRSF000116 3 209 2.2E-40 T 14-10-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 MB46_10215 d123106edbd1c84ba70ef03d392cd44b 341 PIRSF PIRSF000116 203 330 5.9E-13 T 14-10-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 MB46_10215 d123106edbd1c84ba70ef03d392cd44b 341 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 15 178 3.4E-75 T 14-10-2018 IPR013116 Ketol-acid reductoisomerase, N-terminal KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 MB46_18090 b9bd1e0552b588399b42a0108e641ad8 449 SMART SM00388 228 291 9.5E-13 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MB46_18090 b9bd1e0552b588399b42a0108e641ad8 449 SMART SM00387 335 444 1.0E-30 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MB46_18090 b9bd1e0552b588399b42a0108e641ad8 449 Pfam PF00672 HAMP domain 174 223 3.2E-8 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MB46_18090 b9bd1e0552b588399b42a0108e641ad8 449 Pfam PF00512 His Kinase A (phospho-acceptor) domain 230 289 5.8E-12 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MB46_18090 b9bd1e0552b588399b42a0108e641ad8 449 Gene3D G3DSA:3.30.565.10 296 443 2.5E-33 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MB46_18090 b9bd1e0552b588399b42a0108e641ad8 449 SUPERFAMILY SSF55874 281 443 6.29E-35 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MB46_18090 b9bd1e0552b588399b42a0108e641ad8 449 Gene3D G3DSA:1.10.287.130 178 291 7.1E-26 T 14-10-2018 MB46_18090 b9bd1e0552b588399b42a0108e641ad8 449 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 335 441 1.3E-19 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MB46_18090 b9bd1e0552b588399b42a0108e641ad8 449 SUPERFAMILY SSF158472 175 224 4.32E-7 T 14-10-2018 MB46_18090 b9bd1e0552b588399b42a0108e641ad8 449 SMART SM00304 174 227 1.9E-9 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MB46_18090 b9bd1e0552b588399b42a0108e641ad8 449 SUPERFAMILY SSF47384 211 288 1.88E-14 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MB46_18090 b9bd1e0552b588399b42a0108e641ad8 449 PRINTS PR00344 Bacterial sensor protein C-terminal signature 405 423 1.5E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MB46_18090 b9bd1e0552b588399b42a0108e641ad8 449 PRINTS PR00344 Bacterial sensor protein C-terminal signature 372 386 1.5E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MB46_18090 b9bd1e0552b588399b42a0108e641ad8 449 PRINTS PR00344 Bacterial sensor protein C-terminal signature 428 441 1.5E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MB46_18090 b9bd1e0552b588399b42a0108e641ad8 449 PRINTS PR00344 Bacterial sensor protein C-terminal signature 390 400 1.5E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MB46_01280 6d01bd81042aaf505c610e3a8b6cf59d 233 Pfam PF07729 FCD domain 88 213 1.5E-27 T 14-10-2018 IPR011711 GntR, C-terminal MB46_01280 6d01bd81042aaf505c610e3a8b6cf59d 233 SUPERFAMILY SSF48008 84 220 4.71E-27 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MB46_01280 6d01bd81042aaf505c610e3a8b6cf59d 233 Gene3D G3DSA:1.20.120.530 82 225 1.1E-30 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MB46_01280 6d01bd81042aaf505c610e3a8b6cf59d 233 SMART SM00345 19 77 2.9E-10 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MB46_01280 6d01bd81042aaf505c610e3a8b6cf59d 233 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 77 2.0E-13 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MB46_01280 6d01bd81042aaf505c610e3a8b6cf59d 233 Gene3D G3DSA:1.10.10.10 11 78 6.3E-16 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_01280 6d01bd81042aaf505c610e3a8b6cf59d 233 SMART SM00895 88 215 8.5E-23 T 14-10-2018 IPR011711 GntR, C-terminal MB46_01280 6d01bd81042aaf505c610e3a8b6cf59d 233 SUPERFAMILY SSF46785 11 93 4.16E-15 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_05105 1dcb8f53d8ab45eb5435b115a70a2ae1 712 Pfam PF02780 Transketolase, C-terminal domain 590 695 8.7E-12 T 14-10-2018 IPR033248 Transketolase, C-terminal domain MB46_05105 1dcb8f53d8ab45eb5435b115a70a2ae1 712 Pfam PF02779 Transketolase, pyrimidine binding domain 372 551 4.4E-39 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain MB46_05105 1dcb8f53d8ab45eb5435b115a70a2ae1 712 SUPERFAMILY SSF52518 359 553 2.36E-60 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold MB46_05105 1dcb8f53d8ab45eb5435b115a70a2ae1 712 Gene3D G3DSA:3.40.50.970 353 557 1.3E-69 T 14-10-2018 MB46_05105 1dcb8f53d8ab45eb5435b115a70a2ae1 712 SUPERFAMILY SSF52922 569 704 2.36E-37 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 MB46_05105 1dcb8f53d8ab45eb5435b115a70a2ae1 712 ProSitePatterns PS00801 Transketolase signature 1. 23 43 - T 14-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 MB46_05105 1dcb8f53d8ab45eb5435b115a70a2ae1 712 SMART SM00861 372 552 1.5E-58 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain MB46_05105 1dcb8f53d8ab45eb5435b115a70a2ae1 712 ProSitePatterns PS00802 Transketolase signature 2. 494 510 - T 14-10-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 MB46_05105 1dcb8f53d8ab45eb5435b115a70a2ae1 712 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 15 356 1.0E-129 T 14-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 MB46_05105 1dcb8f53d8ab45eb5435b115a70a2ae1 712 SUPERFAMILY SSF52518 4 342 1.61E-96 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold MB46_05105 1dcb8f53d8ab45eb5435b115a70a2ae1 712 TIGRFAM TIGR00232 tktlase_bact: transketolase 18 701 2.7E-221 T 14-10-2018 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 MB46_05105 1dcb8f53d8ab45eb5435b115a70a2ae1 712 Gene3D G3DSA:3.40.50.970 4 352 1.1E-108 T 14-10-2018 MB46_05105 1dcb8f53d8ab45eb5435b115a70a2ae1 712 Gene3D G3DSA:3.40.50.920 574 704 1.2E-39 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 MB46_04610 56f8f34358c08c20c4a176212980f212 337 Gene3D G3DSA:3.30.450.40 103 335 2.2E-33 T 14-10-2018 IPR029016 GAF-like domain superfamily MB46_04610 56f8f34358c08c20c4a176212980f212 337 SUPERFAMILY SSF55781 71 336 9.81E-47 T 14-10-2018 MB46_04610 56f8f34358c08c20c4a176212980f212 337 Pfam PF01628 HrcA protein C terminal domain 103 321 2.0E-55 T 14-10-2018 IPR021153 Heat-inducible transcription repressor HrcA, C-terminal GO:0003677|GO:0006355 MB46_04610 56f8f34358c08c20c4a176212980f212 337 Hamap MF_00081 Heat-inducible transcription repressor HrcA [hrcA]. 1 328 25.489 T 14-10-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 MB46_04610 56f8f34358c08c20c4a176212980f212 337 Gene3D G3DSA:3.30.390.60 127 228 2.2E-33 T 14-10-2018 IPR023120 Winged helix-turn-helix transcription repressor, HrcA, inserted dimerising domain superfamily MB46_04610 56f8f34358c08c20c4a176212980f212 337 SUPERFAMILY SSF46785 2 82 4.15E-23 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_04610 56f8f34358c08c20c4a176212980f212 337 TIGRFAM TIGR00331 hrcA: heat-inducible transcription repressor HrcA 4 334 7.0E-86 T 14-10-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 MB46_04610 56f8f34358c08c20c4a176212980f212 337 PIRSF PIRSF005485 1 337 2.2E-93 T 14-10-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 MB46_04610 56f8f34358c08c20c4a176212980f212 337 Gene3D G3DSA:1.10.10.10 1 84 1.0E-32 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_04610 56f8f34358c08c20c4a176212980f212 337 Pfam PF08220 DeoR-like helix-turn-helix domain 34 56 3.3E-5 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MB46_15645 d0599ee1744859c3a065346fe5640f15 314 SUPERFAMILY SSF53613 3 312 9.04E-54 T 14-10-2018 IPR029056 Ribokinase-like MB46_15645 d0599ee1744859c3a065346fe5640f15 314 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 25 49 - T 14-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 MB46_15645 d0599ee1744859c3a065346fe5640f15 314 Gene3D G3DSA:3.40.1190.20 2 314 2.4E-65 T 14-10-2018 IPR029056 Ribokinase-like MB46_15645 d0599ee1744859c3a065346fe5640f15 314 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 246 259 - T 14-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 MB46_15645 d0599ee1744859c3a065346fe5640f15 314 Pfam PF00294 pfkB family carbohydrate kinase 11 307 3.3E-40 T 14-10-2018 IPR011611 Carbohydrate kinase PfkB MB46_01745 8dd8b9be2d7583157105b43357ee1935 228 SUPERFAMILY SSF48371 11 226 2.13E-63 T 14-10-2018 IPR016024 Armadillo-type fold MB46_01745 8dd8b9be2d7583157105b43357ee1935 228 Pfam PF08713 DNA alkylation repair enzyme 15 193 3.5E-21 T 14-10-2018 IPR014825 DNA alkylation repair enzyme MB46_09540 2bad3a57fb880851f416dd2d6a230ae1 121 Gene3D G3DSA:1.10.10.10 2 117 1.2E-42 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_09540 2bad3a57fb880851f416dd2d6a230ae1 121 SUPERFAMILY SSF46785 3 116 3.24E-34 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_09540 2bad3a57fb880851f416dd2d6a230ae1 121 Pfam PF01638 HxlR-like helix-turn-helix 18 104 4.1E-27 T 14-10-2018 IPR002577 Helix-turn-helix, HxlR type MB46_09660 b55e578ecffb7e38dc95b498ff416d67 559 ProDom PD141294 TRANSMEMBRANE MEMBRANE PROTEIN GTRIV-SF YFDI PREDICTED 101 419 2.0E-5 T 14-10-2018 MB46_05495 7c012b1b1bfaf1a32bccde5f6a5a03b7 289 SUPERFAMILY SSF53335 20 219 2.15E-26 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MB46_05495 7c012b1b1bfaf1a32bccde5f6a5a03b7 289 PIRSF PIRSF018249 1 286 1.4E-74 T 14-10-2018 IPR016718 rRNA (guanine-N1-)-methyltransferase A, predicted GO:0008168 MB46_05495 7c012b1b1bfaf1a32bccde5f6a5a03b7 289 Gene3D G3DSA:3.40.50.150 8 285 1.5E-57 T 14-10-2018 MB46_05495 7c012b1b1bfaf1a32bccde5f6a5a03b7 289 Pfam PF13649 Methyltransferase domain 98 184 2.3E-7 T 14-10-2018 MB46_01105 19182cd94e6bfa2f4eac29c5325be519 276 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 230 245 - T 14-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 MB46_01105 19182cd94e6bfa2f4eac29c5325be519 276 PRINTS PR00069 Aldo-keto reductase signature 126 143 8.2E-50 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MB46_01105 19182cd94e6bfa2f4eac29c5325be519 276 PRINTS PR00069 Aldo-keto reductase signature 160 189 8.2E-50 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MB46_01105 19182cd94e6bfa2f4eac29c5325be519 276 PRINTS PR00069 Aldo-keto reductase signature 38 62 8.2E-50 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MB46_01105 19182cd94e6bfa2f4eac29c5325be519 276 PRINTS PR00069 Aldo-keto reductase signature 94 112 8.2E-50 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MB46_01105 19182cd94e6bfa2f4eac29c5325be519 276 PRINTS PR00069 Aldo-keto reductase signature 197 221 8.2E-50 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MB46_01105 19182cd94e6bfa2f4eac29c5325be519 276 Gene3D G3DSA:3.20.20.100 1 276 1.2E-112 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily MB46_01105 19182cd94e6bfa2f4eac29c5325be519 276 PIRSF PIRSF000097 1 272 2.8E-82 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MB46_01105 19182cd94e6bfa2f4eac29c5325be519 276 SUPERFAMILY SSF51430 7 267 3.27E-95 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily MB46_01105 19182cd94e6bfa2f4eac29c5325be519 276 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 42 59 - T 14-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 MB46_01105 19182cd94e6bfa2f4eac29c5325be519 276 Pfam PF00248 Aldo/keto reductase family 25 262 2.1E-49 T 14-10-2018 IPR023210 NADP-dependent oxidoreductase domain MB46_01105 19182cd94e6bfa2f4eac29c5325be519 276 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 126 143 - T 14-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 MB46_07025 ca73cd1f0c7e809551a50efa32f7268f 459 Gene3D G3DSA:1.20.1250.20 13 446 1.4E-62 T 14-10-2018 MB46_07025 ca73cd1f0c7e809551a50efa32f7268f 459 Pfam PF07690 Major Facilitator Superfamily 21 371 9.2E-32 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MB46_07025 ca73cd1f0c7e809551a50efa32f7268f 459 ProSitePatterns PS00216 Sugar transport proteins signature 1. 302 318 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MB46_07025 ca73cd1f0c7e809551a50efa32f7268f 459 SUPERFAMILY SSF103473 10 429 8.24E-67 T 14-10-2018 IPR036259 MFS transporter superfamily MB46_05695 c4185e9c6f804f7a574e8ca85cbe596d 289 Pfam PF00950 ABC 3 transport family 13 266 1.5E-77 T 14-10-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 MB46_05695 c4185e9c6f804f7a574e8ca85cbe596d 289 SUPERFAMILY SSF81345 5 263 1.12E-36 T 14-10-2018 IPR037294 ABC transporter, BtuC-like MB46_05695 c4185e9c6f804f7a574e8ca85cbe596d 289 Gene3D G3DSA:1.10.3470.10 62 272 2.3E-6 T 14-10-2018 IPR037294 ABC transporter, BtuC-like MB46_02835 01b59c92763ac1b450b34ffd5c5ff4a8 415 Gene3D G3DSA:3.30.450.40 8 193 4.6E-43 T 14-10-2018 IPR029016 GAF-like domain superfamily MB46_02835 01b59c92763ac1b450b34ffd5c5ff4a8 415 SMART SM00862 240 309 0.0018 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MB46_03745 b9d9e3d76cd047cad71a02f01a3b50a7 209 SUPERFAMILY SSF74942 110 152 2.48E-5 T 14-10-2018 IPR036847 Ribosome maturation factor RimP, C-terminal domain superfamily MB46_03745 b9d9e3d76cd047cad71a02f01a3b50a7 209 Gene3D G3DSA:3.30.300.70 22 106 8.6E-10 T 14-10-2018 IPR035956 RimP, N-terminal domain superfamily MB46_03745 b9d9e3d76cd047cad71a02f01a3b50a7 209 Pfam PF17384 RimP C-terminal SH3 domain 112 184 2.2E-7 T 14-10-2018 IPR028998 Ribosome maturation factor RimP, C-terminal MB46_03745 b9d9e3d76cd047cad71a02f01a3b50a7 209 SUPERFAMILY SSF75420 26 108 1.83E-13 T 14-10-2018 IPR035956 RimP, N-terminal domain superfamily MB46_03745 b9d9e3d76cd047cad71a02f01a3b50a7 209 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 27 196 19.589 T 14-10-2018 IPR003728 Ribosome maturation factor RimP GO:0042274 MB46_03745 b9d9e3d76cd047cad71a02f01a3b50a7 209 Pfam PF02576 RimP N-terminal domain 33 108 1.7E-13 T 14-10-2018 IPR028989 Ribosome maturation factor RimP, N-terminal MB46_01620 f742be5478a99c529e9283c961607903 355 SUPERFAMILY SSF51604 130 350 3.14E-56 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily MB46_01620 f742be5478a99c529e9283c961607903 355 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 16 120 4.8E-11 T 14-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain MB46_01620 f742be5478a99c529e9283c961607903 355 Pfam PF13378 Enolase C-terminal domain-like 144 352 3.9E-40 T 14-10-2018 IPR029065 Enolase C-terminal domain-like MB46_01620 f742be5478a99c529e9283c961607903 355 Gene3D G3DSA:3.20.20.120 112 350 9.4E-90 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily MB46_01620 f742be5478a99c529e9283c961607903 355 SUPERFAMILY SSF54826 1 120 5.46E-23 T 14-10-2018 MB46_01620 f742be5478a99c529e9283c961607903 355 Gene3D G3DSA:3.30.390.10 6 111 9.4E-90 T 14-10-2018 IPR029017 Enolase-like, N-terminal MB46_01620 f742be5478a99c529e9283c961607903 355 SMART SM00922 141 238 3.4E-26 T 14-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal MB46_13525 0cc1f29719608695dbdb604f534d441c 265 SUPERFAMILY SSF82679 82 186 1.96E-35 T 14-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 MB46_13525 0cc1f29719608695dbdb604f534d441c 265 PRINTS PR00338 Transcription termination factor NUSG signature 135 147 2.8E-12 T 14-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 MB46_13525 0cc1f29719608695dbdb604f534d441c 265 PRINTS PR00338 Transcription termination factor NUSG signature 223 238 2.8E-12 T 14-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 MB46_13525 0cc1f29719608695dbdb604f534d441c 265 PRINTS PR00338 Transcription termination factor NUSG signature 241 257 2.8E-12 T 14-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 MB46_13525 0cc1f29719608695dbdb604f534d441c 265 Gene3D G3DSA:3.30.70.940 76 196 1.6E-38 T 14-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 MB46_13525 0cc1f29719608695dbdb604f534d441c 265 Gene3D G3DSA:2.30.30.30 206 265 5.0E-20 T 14-10-2018 IPR014722 Ribosomal protein L2, domain 2 MB46_13525 0cc1f29719608695dbdb604f534d441c 265 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 80 265 22.207 T 14-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 MB46_13525 0cc1f29719608695dbdb604f534d441c 265 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 83 265 4.9E-54 T 14-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 MB46_13525 0cc1f29719608695dbdb604f534d441c 265 Pfam PF02357 Transcription termination factor nusG 82 184 1.0E-22 T 14-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 MB46_13525 0cc1f29719608695dbdb604f534d441c 265 SMART SM00738 80 188 8.6E-40 T 14-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 MB46_13525 0cc1f29719608695dbdb604f534d441c 265 SUPERFAMILY SSF50104 209 265 4.96E-14 T 14-10-2018 IPR008991 Translation protein SH3-like domain superfamily MB46_13525 0cc1f29719608695dbdb604f534d441c 265 SMART SM00739 211 238 1.1E-4 T 14-10-2018 IPR005824 KOW MB46_07700 87d2d60f721438e2f9eeeff16ee80d31 215 Gene3D G3DSA:2.40.30.20 1 90 7.1E-26 T 14-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 MB46_07700 87d2d60f721438e2f9eeeff16ee80d31 215 Pfam PF00677 Lumazine binding domain 3 87 2.7E-18 T 14-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MB46_07700 87d2d60f721438e2f9eeeff16ee80d31 215 Pfam PF00677 Lumazine binding domain 101 190 3.9E-25 T 14-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MB46_07700 87d2d60f721438e2f9eeeff16ee80d31 215 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 1 206 4.3E-57 T 14-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MB46_07700 87d2d60f721438e2f9eeeff16ee80d31 215 Gene3D G3DSA:2.40.30.20 103 212 6.7E-34 T 14-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 MB46_07700 87d2d60f721438e2f9eeeff16ee80d31 215 SUPERFAMILY SSF63380 95 205 7.99E-30 T 14-10-2018 IPR017938 Riboflavin synthase-like beta-barrel MB46_07700 87d2d60f721438e2f9eeeff16ee80d31 215 SUPERFAMILY SSF63380 1 90 3.06E-22 T 14-10-2018 IPR017938 Riboflavin synthase-like beta-barrel MB46_07700 87d2d60f721438e2f9eeeff16ee80d31 215 PIRSF PIRSF000498 1 214 1.9E-65 T 14-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MB46_02395 860d6763df7bc8d13b410dcbf0396225 796 SMART SM00460 517 596 1.3E-18 T 14-10-2018 IPR002931 Transglutaminase-like MB46_02395 860d6763df7bc8d13b410dcbf0396225 796 Pfam PF01841 Transglutaminase-like superfamily 466 594 2.5E-22 T 14-10-2018 IPR002931 Transglutaminase-like MB46_02395 860d6763df7bc8d13b410dcbf0396225 796 Gene3D G3DSA:3.10.620.30 454 614 1.2E-17 T 14-10-2018 MB46_02395 860d6763df7bc8d13b410dcbf0396225 796 SUPERFAMILY SSF54001 452 604 8.13E-29 T 14-10-2018 IPR038765 Papain-like cysteine peptidase superfamily MB46_14505 6f12a23148b06fcc3a75d4d9a6f7d142 553 Gene3D G3DSA:3.40.50.300 363 543 1.1E-34 T 14-10-2018 MB46_14505 6f12a23148b06fcc3a75d4d9a6f7d142 553 SMART SM00382 384 548 1.0E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_14505 6f12a23148b06fcc3a75d4d9a6f7d142 553 SMART SM00382 31 221 1.2E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_14505 6f12a23148b06fcc3a75d4d9a6f7d142 553 Pfam PF00005 ABC transporter 29 177 3.1E-16 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_14505 6f12a23148b06fcc3a75d4d9a6f7d142 553 SUPERFAMILY SSF52540 371 538 6.17E-31 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_14505 6f12a23148b06fcc3a75d4d9a6f7d142 553 SUPERFAMILY SSF52540 19 221 2.52E-36 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_14505 6f12a23148b06fcc3a75d4d9a6f7d142 553 Pfam PF00005 ABC transporter 377 503 6.4E-16 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_14505 6f12a23148b06fcc3a75d4d9a6f7d142 553 Gene3D G3DSA:3.40.50.300 4 289 6.0E-44 T 14-10-2018 MB46_02220 062378a55d9179bcd70bfa4e030ae02d 413 Pfam PF01238 Phosphomannose isomerase type I 1 366 9.9E-69 T 14-10-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 MB46_02220 062378a55d9179bcd70bfa4e030ae02d 413 Gene3D G3DSA:1.10.441.10 149 315 4.4E-129 T 14-10-2018 MB46_02220 062378a55d9179bcd70bfa4e030ae02d 413 Gene3D G3DSA:2.60.120.10 316 394 4.4E-129 T 14-10-2018 IPR014710 RmlC-like jelly roll fold MB46_02220 062378a55d9179bcd70bfa4e030ae02d 413 PRINTS PR00714 Phosphomannose isomerase type I signature 125 148 3.9E-60 T 14-10-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 MB46_02220 062378a55d9179bcd70bfa4e030ae02d 413 PRINTS PR00714 Phosphomannose isomerase type I signature 251 270 3.9E-60 T 14-10-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 MB46_02220 062378a55d9179bcd70bfa4e030ae02d 413 PRINTS PR00714 Phosphomannose isomerase type I signature 270 289 3.9E-60 T 14-10-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 MB46_02220 062378a55d9179bcd70bfa4e030ae02d 413 PRINTS PR00714 Phosphomannose isomerase type I signature 80 101 3.9E-60 T 14-10-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 MB46_02220 062378a55d9179bcd70bfa4e030ae02d 413 PRINTS PR00714 Phosphomannose isomerase type I signature 289 308 3.9E-60 T 14-10-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 MB46_02220 062378a55d9179bcd70bfa4e030ae02d 413 PRINTS PR00714 Phosphomannose isomerase type I signature 4 22 3.9E-60 T 14-10-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 MB46_02220 062378a55d9179bcd70bfa4e030ae02d 413 PRINTS PR00714 Phosphomannose isomerase type I signature 31 46 3.9E-60 T 14-10-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 MB46_02220 062378a55d9179bcd70bfa4e030ae02d 413 PRINTS PR00714 Phosphomannose isomerase type I signature 235 250 3.9E-60 T 14-10-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 MB46_02220 062378a55d9179bcd70bfa4e030ae02d 413 SUPERFAMILY SSF51182 1 393 2.39E-91 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily MB46_02220 062378a55d9179bcd70bfa4e030ae02d 413 TIGRFAM TIGR00218 manA: mannose-6-phosphate isomerase, class I 3 394 1.4E-70 T 14-10-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 MB46_02220 062378a55d9179bcd70bfa4e030ae02d 413 PIRSF PIRSF001480 1 412 2.8E-99 T 14-10-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 MB46_02220 062378a55d9179bcd70bfa4e030ae02d 413 Gene3D G3DSA:2.60.120.10 6 290 4.4E-129 T 14-10-2018 IPR014710 RmlC-like jelly roll fold MB46_05375 d460bed5d476c1e7957c2c8eb449f743 293 Gene3D G3DSA:1.10.287.100 228 266 8.0E-86 T 14-10-2018 MB46_05375 d460bed5d476c1e7957c2c8eb449f743 293 Pfam PF09754 PAC2 family 29 246 1.7E-44 T 14-10-2018 IPR019151 Proteasome assembly chaperone 2 MB46_05375 d460bed5d476c1e7957c2c8eb449f743 293 Gene3D G3DSA:3.40.50.10900 24 227 8.0E-86 T 14-10-2018 IPR038389 Proteasome assembly chaperone 2 superfamily MB46_05375 d460bed5d476c1e7957c2c8eb449f743 293 PIRSF PIRSF028754 12 293 3.0E-86 T 14-10-2018 IPR008492 Protein of unknown function DUF774 MB46_05375 d460bed5d476c1e7957c2c8eb449f743 293 SUPERFAMILY SSF159659 23 270 2.35E-77 T 14-10-2018 MB46_05905 85bd5bf450b90aac514e7f7ac2200ac8 192 Gene3D G3DSA:3.40.430.10 2 187 6.6E-33 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 MB46_05905 85bd5bf450b90aac514e7f7ac2200ac8 192 Pfam PF01872 RibD C-terminal domain 2 178 1.0E-6 T 14-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 MB46_05905 85bd5bf450b90aac514e7f7ac2200ac8 192 SUPERFAMILY SSF53597 2 188 2.23E-26 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 MB46_17890 f0f5dd4f7bf5dc672c2b2d21e0d56aa1 145 Gene3D G3DSA:3.10.180.10 1 145 1.1E-50 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MB46_17890 f0f5dd4f7bf5dc672c2b2d21e0d56aa1 145 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 8 113 2.2E-11 T 14-10-2018 MB46_17890 f0f5dd4f7bf5dc672c2b2d21e0d56aa1 145 SUPERFAMILY SSF54593 1 140 3.16E-32 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MB46_11305 86fe20c24cc7ed270efe96ffbe24ac75 328 SUPERFAMILY SSF51445 41 327 1.37E-49 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily MB46_11305 86fe20c24cc7ed270efe96ffbe24ac75 328 Gene3D G3DSA:3.20.20.300 1 322 4.8E-78 T 14-10-2018 IPR036962 Glycoside hydrolase, family 3, N-terminal domain superfamily GO:0004553|GO:0005975 MB46_11305 86fe20c24cc7ed270efe96ffbe24ac75 328 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 18 303 1.0E-34 T 14-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 MB46_02565 74fc0f2864698b00e4ff0a3d790a6740 462 TIGRFAM TIGR03025 EPS_sugtrans: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 3 461 2.6E-122 T 14-10-2018 IPR017475 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase MB46_02565 74fc0f2864698b00e4ff0a3d790a6740 462 Pfam PF02397 Bacterial sugar transferase 268 456 2.4E-66 T 14-10-2018 IPR003362 Bacterial sugar transferase MB46_02565 74fc0f2864698b00e4ff0a3d790a6740 462 Pfam PF13727 CoA-binding domain 65 181 6.9E-7 T 14-10-2018 MB46_15785 cd8ddf53f47f7d77583b04a6ee444903 193 Gene3D G3DSA:2.60.60.30 20 187 2.0E-72 T 14-10-2018 MB46_15785 cd8ddf53f47f7d77583b04a6ee444903 193 Pfam PF02342 TerD domain 4 188 2.3E-77 T 14-10-2018 IPR003325 TerD domain MB46_14545 1cfde978e32f08f2b9e5bc7eaa61c092 673 Gene3D G3DSA:2.60.40.1180 619 666 4.7E-5 T 14-10-2018 IPR013780 Glycosyl hydrolase, all-beta MB46_14545 1cfde978e32f08f2b9e5bc7eaa61c092 673 Gene3D G3DSA:3.40.50.880 397 613 1.9E-56 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like MB46_14545 1cfde978e32f08f2b9e5bc7eaa61c092 673 Pfam PF02449 Beta-galactosidase 22 388 4.4E-141 T 14-10-2018 IPR013529 Glycoside hydrolase, family 42, N-terminal GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 MB46_14545 1cfde978e32f08f2b9e5bc7eaa61c092 673 PIRSF PIRSF001084 11 667 9.7E-223 T 14-10-2018 IPR003476 Glycoside hydrolase, family 42 GO:0004565|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 MB46_14545 1cfde978e32f08f2b9e5bc7eaa61c092 673 Gene3D G3DSA:3.20.20.80 12 395 2.3E-132 T 14-10-2018 MB46_14545 1cfde978e32f08f2b9e5bc7eaa61c092 673 Pfam PF08532 Beta-galactosidase trimerisation domain 400 610 5.0E-45 T 14-10-2018 IPR013738 Beta-galactosidase trimerisation GO:0004565|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 MB46_14545 1cfde978e32f08f2b9e5bc7eaa61c092 673 SUPERFAMILY SSF52317 396 610 2.29E-42 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like MB46_14545 1cfde978e32f08f2b9e5bc7eaa61c092 673 SUPERFAMILY SSF51445 17 369 4.77E-110 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily MB46_15570 1dc31d8e516325794e489bdd45bb199d 430 TIGRFAM TIGR00414 serS: serine--tRNA ligase 2 416 8.6E-125 T 14-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 MB46_15570 1dc31d8e516325794e489bdd45bb199d 430 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 106 3.4E-21 T 14-10-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 MB46_15570 1dc31d8e516325794e489bdd45bb199d 430 PRINTS PR00981 Seryl-tRNA synthetase signature 329 345 7.8E-31 T 14-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 MB46_15570 1dc31d8e516325794e489bdd45bb199d 430 PRINTS PR00981 Seryl-tRNA synthetase signature 260 272 7.8E-31 T 14-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 MB46_15570 1dc31d8e516325794e489bdd45bb199d 430 PRINTS PR00981 Seryl-tRNA synthetase signature 272 285 7.8E-31 T 14-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 MB46_15570 1dc31d8e516325794e489bdd45bb199d 430 PRINTS PR00981 Seryl-tRNA synthetase signature 312 325 7.8E-31 T 14-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 MB46_15570 1dc31d8e516325794e489bdd45bb199d 430 PRINTS PR00981 Seryl-tRNA synthetase signature 347 363 7.8E-31 T 14-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 MB46_15570 1dc31d8e516325794e489bdd45bb199d 430 PIRSF PIRSF001529 1 424 6.1E-131 T 14-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 MB46_15570 1dc31d8e516325794e489bdd45bb199d 430 Gene3D G3DSA:1.10.287.40 1 103 1.3E-18 T 14-10-2018 MB46_15570 1dc31d8e516325794e489bdd45bb199d 430 SUPERFAMILY SSF46589 2 111 9.42E-22 T 14-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 MB46_15570 1dc31d8e516325794e489bdd45bb199d 430 Gene3D G3DSA:3.30.930.10 104 429 9.8E-110 T 14-10-2018 MB46_15570 1dc31d8e516325794e489bdd45bb199d 430 SUPERFAMILY SSF55681 116 424 1.06E-76 T 14-10-2018 MB46_15570 1dc31d8e516325794e489bdd45bb199d 430 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 421 36.763 T 14-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 MB46_15570 1dc31d8e516325794e489bdd45bb199d 430 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 220 399 1.1E-22 T 14-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 MB46_14990 1cee30909b883a23067038d2f885336e 289 SUPERFAMILY SSF161098 26 289 5.49E-67 T 14-10-2018 IPR035906 MetI-like superfamily MB46_14990 1cee30909b883a23067038d2f885336e 289 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 102 283 3.2E-15 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_14990 1cee30909b883a23067038d2f885336e 289 Gene3D G3DSA:1.10.3720.10 21 280 1.4E-54 T 14-10-2018 IPR035906 MetI-like superfamily MB46_00325 2c392eb66dfc6adaded490db08aa3608 246 Pfam PF07702 UTRA domain 100 237 4.1E-29 T 14-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 MB46_00325 2c392eb66dfc6adaded490db08aa3608 246 SMART SM00345 21 80 3.8E-14 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MB46_00325 2c392eb66dfc6adaded490db08aa3608 246 Gene3D G3DSA:3.40.1410.10 81 246 5.8E-38 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily MB46_00325 2c392eb66dfc6adaded490db08aa3608 246 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 54 6.6E-6 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MB46_00325 2c392eb66dfc6adaded490db08aa3608 246 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 54 70 6.6E-6 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MB46_00325 2c392eb66dfc6adaded490db08aa3608 246 SUPERFAMILY SSF46785 10 84 6.39E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_00325 2c392eb66dfc6adaded490db08aa3608 246 SMART SM00866 100 238 8.2E-29 T 14-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 MB46_00325 2c392eb66dfc6adaded490db08aa3608 246 Pfam PF00392 Bacterial regulatory proteins, gntR family 17 80 3.4E-15 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MB46_00325 2c392eb66dfc6adaded490db08aa3608 246 Gene3D G3DSA:1.10.10.10 5 80 1.7E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_00325 2c392eb66dfc6adaded490db08aa3608 246 SUPERFAMILY SSF64288 68 243 6.6E-42 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily MB46_16490 76c7bed1d5c87bba67696b0a90c7d9f4 230 SUPERFAMILY SSF46785 17 89 2.38E-15 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_16490 76c7bed1d5c87bba67696b0a90c7d9f4 230 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 59 75 3.1E-6 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MB46_16490 76c7bed1d5c87bba67696b0a90c7d9f4 230 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 45 59 3.1E-6 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MB46_16490 76c7bed1d5c87bba67696b0a90c7d9f4 230 Gene3D G3DSA:1.10.10.10 20 86 6.6E-16 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_16490 76c7bed1d5c87bba67696b0a90c7d9f4 230 SUPERFAMILY SSF48008 94 227 6.8E-15 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MB46_16490 76c7bed1d5c87bba67696b0a90c7d9f4 230 SMART SM00345 27 85 1.4E-12 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MB46_16490 76c7bed1d5c87bba67696b0a90c7d9f4 230 Pfam PF00392 Bacterial regulatory proteins, gntR family 25 85 4.0E-12 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MB46_16490 76c7bed1d5c87bba67696b0a90c7d9f4 230 Pfam PF07729 FCD domain 96 228 5.3E-15 T 14-10-2018 IPR011711 GntR, C-terminal MB46_16490 76c7bed1d5c87bba67696b0a90c7d9f4 230 Gene3D G3DSA:1.20.120.530 92 230 8.9E-19 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MB46_16490 76c7bed1d5c87bba67696b0a90c7d9f4 230 SMART SM00895 95 229 3.7E-5 T 14-10-2018 IPR011711 GntR, C-terminal MB46_10675 a749c7751268554f01467c692d21d2be 363 Gene3D G3DSA:1.10.4080.10 13 363 6.6E-50 T 14-10-2018 IPR036705 ADP-ribosylation/Crystallin J1 superfamily MB46_10675 a749c7751268554f01467c692d21d2be 363 SUPERFAMILY SSF101478 14 360 9.55E-48 T 14-10-2018 IPR036705 ADP-ribosylation/Crystallin J1 superfamily MB46_10675 a749c7751268554f01467c692d21d2be 363 Pfam PF03747 ADP-ribosylglycohydrolase 21 337 1.4E-48 T 14-10-2018 IPR005502 ADP-ribosylation/Crystallin J1 MB46_10505 57aa28e5f83f5baf0d3803668b8ce988 371 SUPERFAMILY SSF51679 1 333 8.11E-71 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 MB46_10505 57aa28e5f83f5baf0d3803668b8ce988 371 Gene3D G3DSA:3.20.20.30 1 345 7.8E-68 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 MB46_10505 57aa28e5f83f5baf0d3803668b8ce988 371 Pfam PF00296 Luciferase-like monooxygenase 1 290 6.0E-57 T 14-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MB46_10505 57aa28e5f83f5baf0d3803668b8ce988 371 TIGRFAM TIGR04036 LLM_CE1758_fam: putative luciferase-like monooxygenase, FMN-dependent, CE1758 family 1 354 3.8E-204 T 14-10-2018 IPR023934 Luciferase-like monooxygenase, FMN-dependent, putative MB46_09870 5ab469f5f94b7ebefab4ce7f35e47a36 281 Gene3D G3DSA:3.40.50.300 3 264 2.6E-62 T 14-10-2018 MB46_09870 5ab469f5f94b7ebefab4ce7f35e47a36 281 SUPERFAMILY SSF52540 7 241 1.44E-52 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_09870 5ab469f5f94b7ebefab4ce7f35e47a36 281 SMART SM00382 31 226 7.4E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_09870 5ab469f5f94b7ebefab4ce7f35e47a36 281 Pfam PF00005 ABC transporter 23 177 3.4E-27 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_05425 a9e8e6eccf17d52688e31e97b5b13f67 323 Gene3D G3DSA:3.10.50.40 215 321 2.5E-27 T 14-10-2018 MB46_05425 a9e8e6eccf17d52688e31e97b5b13f67 323 SUPERFAMILY SSF54534 218 319 4.12E-26 T 14-10-2018 MB46_05425 a9e8e6eccf17d52688e31e97b5b13f67 323 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 234 319 1.2E-15 T 14-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain MB46_07270 c76df30a71898bf74f8d20551835cb3c 211 Gene3D G3DSA:1.10.10.60 11 71 9.8E-19 T 14-10-2018 MB46_07270 c76df30a71898bf74f8d20551835cb3c 211 Gene3D G3DSA:1.10.357.10 72 200 2.4E-29 T 14-10-2018 MB46_07270 c76df30a71898bf74f8d20551835cb3c 211 SUPERFAMILY SSF46689 11 91 7.7E-14 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MB46_07270 c76df30a71898bf74f8d20551835cb3c 211 SUPERFAMILY SSF48498 90 198 3.02E-21 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily MB46_07270 c76df30a71898bf74f8d20551835cb3c 211 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 70 8.0E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MB46_07975 9f92546f0746702cb852bce084b3fd42 589 SUPERFAMILY SSF56300 48 253 3.57E-20 T 14-10-2018 MB46_07975 9f92546f0746702cb852bce084b3fd42 589 Gene3D G3DSA:3.60.21.10 31 274 8.9E-10 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like MB46_07975 9f92546f0746702cb852bce084b3fd42 589 Pfam PF00149 Calcineurin-like phosphoesterase 48 245 1.0E-7 T 14-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 MB46_07975 9f92546f0746702cb852bce084b3fd42 589 SUPERFAMILY SSF49899 340 585 1.96E-23 T 14-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily MB46_07975 9f92546f0746702cb852bce084b3fd42 589 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 428 585 8.9E-15 T 14-10-2018 MB46_07975 9f92546f0746702cb852bce084b3fd42 589 Gene3D G3DSA:2.60.120.200 353 587 1.5E-15 T 14-10-2018 MB46_01540 d533060e5d99eb32f8b523f7b697d19b 193 Pfam PF01381 Helix-turn-helix 16 70 5.6E-17 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MB46_01540 d533060e5d99eb32f8b523f7b697d19b 193 Pfam PF07883 Cupin domain 117 177 5.4E-13 T 14-10-2018 IPR013096 Cupin 2, conserved barrel MB46_01540 d533060e5d99eb32f8b523f7b697d19b 193 Gene3D G3DSA:1.10.260.40 10 81 1.1E-17 T 14-10-2018 MB46_01540 d533060e5d99eb32f8b523f7b697d19b 193 SMART SM00530 15 70 6.1E-18 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MB46_01540 d533060e5d99eb32f8b523f7b697d19b 193 SUPERFAMILY SSF47413 11 74 7.32E-18 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MB46_01540 d533060e5d99eb32f8b523f7b697d19b 193 SUPERFAMILY SSF51182 66 176 8.63E-24 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily MB46_01540 d533060e5d99eb32f8b523f7b697d19b 193 Gene3D G3DSA:2.60.120.10 82 192 5.5E-15 T 14-10-2018 IPR014710 RmlC-like jelly roll fold MB46_10090 1e568c86cb647c3f48420e85337e0c3d 387 Gene3D G3DSA:1.10.600.10 36 387 1.4E-76 T 14-10-2018 IPR008949 Isoprenoid synthase domain superfamily MB46_10090 1e568c86cb647c3f48420e85337e0c3d 387 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 125 139 - T 14-10-2018 IPR033749 Polyprenyl synthetase, conserved site MB46_10090 1e568c86cb647c3f48420e85337e0c3d 387 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 271 283 - T 14-10-2018 IPR033749 Polyprenyl synthetase, conserved site MB46_10090 1e568c86cb647c3f48420e85337e0c3d 387 SUPERFAMILY SSF48576 55 386 1.37E-59 T 14-10-2018 IPR008949 Isoprenoid synthase domain superfamily MB46_10090 1e568c86cb647c3f48420e85337e0c3d 387 Pfam PF00348 Polyprenyl synthetase 82 322 7.1E-48 T 14-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 MB46_11075 562d13fa2ad345f9b0366e766e13e36e 289 SUPERFAMILY SSF81345 10 270 1.22E-32 T 14-10-2018 IPR037294 ABC transporter, BtuC-like MB46_11075 562d13fa2ad345f9b0366e766e13e36e 289 Pfam PF00950 ABC 3 transport family 23 270 2.4E-43 T 14-10-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 MB46_11075 562d13fa2ad345f9b0366e766e13e36e 289 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 59 76 3.1E-6 T 14-10-2018 MB46_11075 562d13fa2ad345f9b0366e766e13e36e 289 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 136 159 3.1E-6 T 14-10-2018 MB46_11075 562d13fa2ad345f9b0366e766e13e36e 289 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 201 224 3.1E-6 T 14-10-2018 MB46_14320 a745987345d9f6456b71cba1f5f30e34 307 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 52 110 9.2E-12 T 14-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 MB46_14320 a745987345d9f6456b71cba1f5f30e34 307 SUPERFAMILY SSF161098 52 261 4.32E-39 T 14-10-2018 IPR035906 MetI-like superfamily MB46_14320 a745987345d9f6456b71cba1f5f30e34 307 Gene3D G3DSA:1.10.3720.10 46 273 4.3E-50 T 14-10-2018 IPR035906 MetI-like superfamily MB46_14320 a745987345d9f6456b71cba1f5f30e34 307 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 70 269 1.6E-15 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_00920 76700fa351ebb69110c255f75bbcdd4b 542 ProSitePatterns PS00296 Chaperonins cpn60 signature. 403 414 - T 14-10-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MB46_00920 76700fa351ebb69110c255f75bbcdd4b 542 Pfam PF00118 TCP-1/cpn60 chaperonin family 22 523 3.4E-90 T 14-10-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 MB46_00920 76700fa351ebb69110c255f75bbcdd4b 542 SUPERFAMILY SSF52029 184 374 1.2E-80 T 14-10-2018 IPR027409 GroEL-like apical domain superfamily MB46_00920 76700fa351ebb69110c255f75bbcdd4b 542 SUPERFAMILY SSF48592 6 519 9.99E-71 T 14-10-2018 IPR027413 GroEL-like equatorial domain superfamily MB46_00920 76700fa351ebb69110c255f75bbcdd4b 542 TIGRFAM TIGR02348 GroEL: chaperonin GroL 2 525 1.1E-243 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MB46_00920 76700fa351ebb69110c255f75bbcdd4b 542 PRINTS PR00298 60kDa chaperonin signature 348 373 7.7E-70 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MB46_00920 76700fa351ebb69110c255f75bbcdd4b 542 PRINTS PR00298 60kDa chaperonin signature 396 417 7.7E-70 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MB46_00920 76700fa351ebb69110c255f75bbcdd4b 542 PRINTS PR00298 60kDa chaperonin signature 82 109 7.7E-70 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MB46_00920 76700fa351ebb69110c255f75bbcdd4b 542 PRINTS PR00298 60kDa chaperonin signature 266 289 7.7E-70 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MB46_00920 76700fa351ebb69110c255f75bbcdd4b 542 PRINTS PR00298 60kDa chaperonin signature 26 52 7.7E-70 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MB46_00920 76700fa351ebb69110c255f75bbcdd4b 542 Gene3D G3DSA:1.10.560.10 7 519 7.5E-218 T 14-10-2018 IPR027413 GroEL-like equatorial domain superfamily MB46_00920 76700fa351ebb69110c255f75bbcdd4b 542 Gene3D G3DSA:3.50.7.10 190 370 7.5E-218 T 14-10-2018 IPR027409 GroEL-like apical domain superfamily MB46_00920 76700fa351ebb69110c255f75bbcdd4b 542 Hamap MF_00600 60 kDa chaperonin [groL]. 1 542 40.731 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MB46_00920 76700fa351ebb69110c255f75bbcdd4b 542 Gene3D G3DSA:3.30.260.10 135 408 7.5E-218 T 14-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily MB46_00920 76700fa351ebb69110c255f75bbcdd4b 542 SUPERFAMILY SSF54849 136 203 3.89E-26 T 14-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily MB46_05475 52aac4010720c54a8e5d7095e837e51e 311 SUPERFAMILY SSF117892 58 192 8.37E-40 T 14-10-2018 IPR036013 Band 7/SPFH domain superfamily MB46_05475 52aac4010720c54a8e5d7095e837e51e 311 Pfam PF01145 SPFH domain / Band 7 family 31 200 1.5E-35 T 14-10-2018 IPR001107 Band 7 domain MB46_05475 52aac4010720c54a8e5d7095e837e51e 311 ProSitePatterns PS01270 Band 7 protein family signature. 141 169 - T 14-10-2018 IPR018080 Band 7/stomatin-like, conserved site MB46_05475 52aac4010720c54a8e5d7095e837e51e 311 PRINTS PR00721 Stomatin signature 82 103 2.1E-32 T 14-10-2018 IPR001972 Stomatin family GO:0016020 MB46_05475 52aac4010720c54a8e5d7095e837e51e 311 PRINTS PR00721 Stomatin signature 34 56 2.1E-32 T 14-10-2018 IPR001972 Stomatin family GO:0016020 MB46_05475 52aac4010720c54a8e5d7095e837e51e 311 PRINTS PR00721 Stomatin signature 180 201 2.1E-32 T 14-10-2018 IPR001972 Stomatin family GO:0016020 MB46_05475 52aac4010720c54a8e5d7095e837e51e 311 PRINTS PR00721 Stomatin signature 161 179 2.1E-32 T 14-10-2018 IPR001972 Stomatin family GO:0016020 MB46_05475 52aac4010720c54a8e5d7095e837e51e 311 PRINTS PR00721 Stomatin signature 137 160 2.1E-32 T 14-10-2018 IPR001972 Stomatin family GO:0016020 MB46_05475 52aac4010720c54a8e5d7095e837e51e 311 PRINTS PR00721 Stomatin signature 117 134 2.1E-32 T 14-10-2018 IPR001972 Stomatin family GO:0016020 MB46_05475 52aac4010720c54a8e5d7095e837e51e 311 Gene3D G3DSA:3.30.479.30 55 187 2.0E-43 T 14-10-2018 MB46_05475 52aac4010720c54a8e5d7095e837e51e 311 SMART SM00244 27 185 2.2E-56 T 14-10-2018 IPR001107 Band 7 domain MB46_08725 52a8d57114821eb23082497a0fd75f8a 670 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 65 667 32.957 T 14-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 MB46_08725 52a8d57114821eb23082497a0fd75f8a 670 Gene3D G3DSA:3.40.50.800 566 670 2.2E-23 T 14-10-2018 IPR036621 Anticodon-binding domain superfamily MB46_08725 52a8d57114821eb23082497a0fd75f8a 670 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 191 237 1.7E-11 T 14-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 MB46_08725 52a8d57114821eb23082497a0fd75f8a 670 Gene3D G3DSA:3.30.980.10 68 240 2.5E-54 T 14-10-2018 MB46_08725 52a8d57114821eb23082497a0fd75f8a 670 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 71 663 2.4E-195 T 14-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 MB46_08725 52a8d57114821eb23082497a0fd75f8a 670 Pfam PF03129 Anticodon binding domain 574 663 8.8E-16 T 14-10-2018 IPR004154 Anticodon-binding MB46_08725 52a8d57114821eb23082497a0fd75f8a 670 Gene3D G3DSA:3.30.930.10 243 565 5.7E-117 T 14-10-2018 MB46_08725 52a8d57114821eb23082497a0fd75f8a 670 SUPERFAMILY SSF52954 560 667 1.3E-26 T 14-10-2018 MB46_08725 52a8d57114821eb23082497a0fd75f8a 670 PRINTS PR01047 Threonyl-tRNA synthetase signature 540 553 1.0E-52 T 14-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 MB46_08725 52a8d57114821eb23082497a0fd75f8a 670 PRINTS PR01047 Threonyl-tRNA synthetase signature 394 417 1.0E-52 T 14-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 MB46_08725 52a8d57114821eb23082497a0fd75f8a 670 PRINTS PR01047 Threonyl-tRNA synthetase signature 567 579 1.0E-52 T 14-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 MB46_08725 52a8d57114821eb23082497a0fd75f8a 670 PRINTS PR01047 Threonyl-tRNA synthetase signature 497 525 1.0E-52 T 14-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 MB46_08725 52a8d57114821eb23082497a0fd75f8a 670 PRINTS PR01047 Threonyl-tRNA synthetase signature 361 389 1.0E-52 T 14-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 MB46_08725 52a8d57114821eb23082497a0fd75f8a 670 SUPERFAMILY SSF55681 261 558 1.39E-93 T 14-10-2018 MB46_08725 52a8d57114821eb23082497a0fd75f8a 670 SUPERFAMILY SSF55186 62 258 1.28E-51 T 14-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 MB46_08725 52a8d57114821eb23082497a0fd75f8a 670 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 356 562 7.2E-38 T 14-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 MB46_08725 52a8d57114821eb23082497a0fd75f8a 670 Gene3D G3DSA:3.30.54.20 129 204 2.5E-54 T 14-10-2018 MB46_08725 52a8d57114821eb23082497a0fd75f8a 670 SMART SM00863 180 237 8.1E-19 T 14-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 MB46_12090 aaf0b19f15a906d28d3239c5c7b40734 212 SUPERFAMILY SSF48498 95 207 5.02E-23 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily MB46_12090 aaf0b19f15a906d28d3239c5c7b40734 212 Pfam PF00440 Bacterial regulatory proteins, tetR family 29 75 1.4E-16 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MB46_12090 aaf0b19f15a906d28d3239c5c7b40734 212 SUPERFAMILY SSF46689 16 95 7.48E-21 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MB46_12090 aaf0b19f15a906d28d3239c5c7b40734 212 Gene3D G3DSA:1.10.357.10 13 212 4.6E-48 T 14-10-2018 MB46_12090 aaf0b19f15a906d28d3239c5c7b40734 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 50 73 1.8E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MB46_12090 aaf0b19f15a906d28d3239c5c7b40734 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 42 1.8E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MB46_08880 be91fda98e9917e472aef6334dfcdf05 340 Gene3D G3DSA:3.40.50.300 18 209 2.5E-44 T 14-10-2018 MB46_08880 be91fda98e9917e472aef6334dfcdf05 340 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 57 187 1.7E-60 T 14-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 MB46_08880 be91fda98e9917e472aef6334dfcdf05 340 Gene3D G3DSA:1.10.8.300 220 337 3.4E-32 T 14-10-2018 MB46_08880 be91fda98e9917e472aef6334dfcdf05 340 PIRSF PIRSF002849 4 340 6.4E-122 T 14-10-2018 MB46_08880 be91fda98e9917e472aef6334dfcdf05 340 SUPERFAMILY SSF52540 23 312 2.93E-38 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_06950 a1a2998a20ce27cb925a8369f0782c3c 214 Gene3D G3DSA:3.40.50.12740 4 204 1.9E-32 T 14-10-2018 MB46_06950 a1a2998a20ce27cb925a8369f0782c3c 214 SUPERFAMILY SSF52172 2 117 2.42E-11 T 14-10-2018 IPR011006 CheY-like superfamily MB46_06950 a1a2998a20ce27cb925a8369f0782c3c 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 144 158 1.0E-9 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_06950 a1a2998a20ce27cb925a8369f0782c3c 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 174 186 1.0E-9 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_06950 a1a2998a20ce27cb925a8369f0782c3c 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 158 174 1.0E-9 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_06950 a1a2998a20ce27cb925a8369f0782c3c 214 SUPERFAMILY SSF46894 138 204 4.76E-18 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MB46_06950 a1a2998a20ce27cb925a8369f0782c3c 214 Pfam PF00196 Bacterial regulatory proteins, luxR family 144 196 1.1E-14 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_06950 a1a2998a20ce27cb925a8369f0782c3c 214 Pfam PF00072 Response regulator receiver domain 6 112 1.3E-4 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MB46_06950 a1a2998a20ce27cb925a8369f0782c3c 214 SMART SM00421 141 198 5.4E-15 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_07775 19fe1a0f8f1620403a5c1b291956c214 104 SUPERFAMILY SSF103481 5 101 2.62E-10 T 14-10-2018 MB46_07775 19fe1a0f8f1620403a5c1b291956c214 104 Gene3D G3DSA:1.10.3730.20 1 104 5.4E-21 T 14-10-2018 MB46_07775 19fe1a0f8f1620403a5c1b291956c214 104 Pfam PF00893 Small Multidrug Resistance protein 1 90 6.5E-17 T 14-10-2018 IPR000390 Small multidrug resistance protein family GO:0016021 MB46_10125 4b9ffcd0813573b98eaf1cac5c2b8056 431 SUPERFAMILY SSF53850 20 428 9.32E-67 T 14-10-2018 MB46_10125 4b9ffcd0813573b98eaf1cac5c2b8056 431 Gene3D G3DSA:3.40.190.10 21 429 8.1E-67 T 14-10-2018 MB46_10125 4b9ffcd0813573b98eaf1cac5c2b8056 431 Pfam PF13416 Bacterial extracellular solute-binding protein 55 365 5.3E-33 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein MB46_06730 36b8f4ae13e5aeadf07800965aa9ea67 562 Pfam PF13185 GAF domain 45 184 5.0E-14 T 14-10-2018 IPR003018 GAF domain GO:0005515 MB46_06730 36b8f4ae13e5aeadf07800965aa9ea67 562 SMART SM00387 470 560 1.2E-5 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MB46_06730 36b8f4ae13e5aeadf07800965aa9ea67 562 SUPERFAMILY SSF55874 438 557 9.04E-14 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MB46_06730 36b8f4ae13e5aeadf07800965aa9ea67 562 Pfam PF07730 Histidine kinase 367 427 3.5E-11 T 14-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 MB46_06730 36b8f4ae13e5aeadf07800965aa9ea67 562 Gene3D G3DSA:3.30.565.10 437 558 5.0E-25 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MB46_06730 36b8f4ae13e5aeadf07800965aa9ea67 562 Gene3D G3DSA:3.30.450.40 218 366 4.0E-14 T 14-10-2018 IPR029016 GAF-like domain superfamily MB46_06730 36b8f4ae13e5aeadf07800965aa9ea67 562 SUPERFAMILY SSF55781 219 356 8.07E-10 T 14-10-2018 MB46_06730 36b8f4ae13e5aeadf07800965aa9ea67 562 SMART SM00065 46 193 8.4E-19 T 14-10-2018 IPR003018 GAF domain GO:0005515 MB46_06730 36b8f4ae13e5aeadf07800965aa9ea67 562 Gene3D G3DSA:3.30.450.40 41 193 1.3E-55 T 14-10-2018 IPR029016 GAF-like domain superfamily MB46_06730 36b8f4ae13e5aeadf07800965aa9ea67 562 SUPERFAMILY SSF55781 28 211 1.88E-36 T 14-10-2018 MB46_19630 7d4adfa50a6c0178b950d3093e5996ff 205 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 65 6.0E-16 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MB46_19630 7d4adfa50a6c0178b950d3093e5996ff 205 SUPERFAMILY SSF46689 18 85 3.64E-16 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MB46_19630 7d4adfa50a6c0178b950d3093e5996ff 205 Gene3D G3DSA:1.10.357.10 14 199 4.1E-54 T 14-10-2018 MB46_19630 7d4adfa50a6c0178b950d3093e5996ff 205 SUPERFAMILY SSF48498 89 174 1.0E-9 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily MB46_19630 7d4adfa50a6c0178b950d3093e5996ff 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 2.3E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MB46_19630 7d4adfa50a6c0178b950d3093e5996ff 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 2.3E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MB46_16705 2b4a704d20ba8161a91f9e93c2a2e07c 368 Pfam PF00005 ABC transporter 18 163 1.2E-35 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_16705 2b4a704d20ba8161a91f9e93c2a2e07c 368 SUPERFAMILY SSF52540 1 239 1.87E-75 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_16705 2b4a704d20ba8161a91f9e93c2a2e07c 368 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_16705 2b4a704d20ba8161a91f9e93c2a2e07c 368 Gene3D G3DSA:3.40.50.300 1 255 4.0E-77 T 14-10-2018 MB46_16705 2b4a704d20ba8161a91f9e93c2a2e07c 368 SMART SM00382 27 221 9.8E-19 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_16925 fc16aca6175bb8c5b0286baea0dfd3e4 191 Gene3D G3DSA:2.70.40.10 2 185 1.1E-59 T 14-10-2018 IPR036157 dUTPase-like superfamily MB46_16925 fc16aca6175bb8c5b0286baea0dfd3e4 191 SUPERFAMILY SSF51283 3 183 7.97E-56 T 14-10-2018 IPR036157 dUTPase-like superfamily MB46_16925 fc16aca6175bb8c5b0286baea0dfd3e4 191 TIGRFAM TIGR02274 dCTP_deam: deoxycytidine triphosphate deaminase 3 181 6.1E-68 T 14-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 MB46_16925 fc16aca6175bb8c5b0286baea0dfd3e4 191 Hamap MF_00146 dCTP deaminase [dcd]. 1 182 34.519 T 14-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 MB46_16925 fc16aca6175bb8c5b0286baea0dfd3e4 191 Pfam PF06559 2'-deoxycytidine 5'-triphosphate deaminase (DCD) 3 153 1.2E-12 T 14-10-2018 IPR010550 Deoxycytidine triphosphate deaminase, bacterial GO:0008829|GO:0009394 MB46_02535 3ba1c269bbe8cf1629bc562481bdc346 341 Pfam PF00535 Glycosyl transferase family 2 23 141 2.4E-19 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MB46_02535 3ba1c269bbe8cf1629bc562481bdc346 341 Gene3D G3DSA:3.90.550.10 2 270 3.9E-30 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MB46_02535 3ba1c269bbe8cf1629bc562481bdc346 341 SUPERFAMILY SSF53448 21 229 1.97E-31 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MB46_14295 d77da9e4a41fdadf83b55ab9541260ee 367 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 244 256 - T 14-10-2018 IPR033749 Polyprenyl synthetase, conserved site MB46_14295 d77da9e4a41fdadf83b55ab9541260ee 367 Pfam PF00348 Polyprenyl synthetase 75 312 2.4E-59 T 14-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 MB46_14295 d77da9e4a41fdadf83b55ab9541260ee 367 Gene3D G3DSA:1.10.600.10 38 366 1.7E-95 T 14-10-2018 IPR008949 Isoprenoid synthase domain superfamily MB46_14295 d77da9e4a41fdadf83b55ab9541260ee 367 SUPERFAMILY SSF48576 56 366 3.2E-78 T 14-10-2018 IPR008949 Isoprenoid synthase domain superfamily MB46_18605 6ef88ebf3635f5d1a95f60c33f08becf 151 SUPERFAMILY SSF55729 1 120 6.18E-16 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase MB46_18605 6ef88ebf3635f5d1a95f60c33f08becf 151 Pfam PF00583 Acetyltransferase (GNAT) family 34 114 1.4E-9 T 14-10-2018 IPR000182 GNAT domain MB46_18605 6ef88ebf3635f5d1a95f60c33f08becf 151 Gene3D G3DSA:3.40.630.30 4 137 2.3E-16 T 14-10-2018 MB46_06820 1b3fcef3b9b05daa5a9ed21b36abc2f9 265 SUPERFAMILY SSF55781 79 256 2.42E-34 T 14-10-2018 MB46_06820 1b3fcef3b9b05daa5a9ed21b36abc2f9 265 Pfam PF01614 Bacterial transcriptional regulator 131 254 3.4E-17 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal MB46_06820 1b3fcef3b9b05daa5a9ed21b36abc2f9 265 Pfam PF09339 IclR helix-turn-helix domain 16 65 1.9E-11 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 MB46_06820 1b3fcef3b9b05daa5a9ed21b36abc2f9 265 SMART SM00346 14 102 0.0042 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 MB46_06820 1b3fcef3b9b05daa5a9ed21b36abc2f9 265 SUPERFAMILY SSF46785 14 75 3.42E-11 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_06820 1b3fcef3b9b05daa5a9ed21b36abc2f9 265 Gene3D G3DSA:3.30.450.40 86 260 2.5E-38 T 14-10-2018 IPR029016 GAF-like domain superfamily MB46_06820 1b3fcef3b9b05daa5a9ed21b36abc2f9 265 Gene3D G3DSA:1.10.10.10 13 78 2.0E-13 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_08005 ba303ed499d2373ee885cb710e03f402 706 PRINTS PR01159 DNA gyrase subunit B signature 11 21 3.9E-28 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MB46_08005 ba303ed499d2373ee885cb710e03f402 706 PRINTS PR01159 DNA gyrase subunit B signature 657 669 3.9E-28 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MB46_08005 ba303ed499d2373ee885cb710e03f402 706 PRINTS PR01159 DNA gyrase subunit B signature 369 385 3.9E-28 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MB46_08005 ba303ed499d2373ee885cb710e03f402 706 PRINTS PR01159 DNA gyrase subunit B signature 224 237 3.9E-28 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MB46_08005 ba303ed499d2373ee885cb710e03f402 706 PRINTS PR01159 DNA gyrase subunit B signature 435 455 3.9E-28 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MB46_08005 ba303ed499d2373ee885cb710e03f402 706 PRINTS PR01159 DNA gyrase subunit B signature 673 689 3.9E-28 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MB46_08005 ba303ed499d2373ee885cb710e03f402 706 PRINTS PR01159 DNA gyrase subunit B signature 257 279 3.9E-28 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MB46_08005 ba303ed499d2373ee885cb710e03f402 706 PRINTS PR01159 DNA gyrase subunit B signature 531 540 3.9E-28 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MB46_08005 ba303ed499d2373ee885cb710e03f402 706 Gene3D G3DSA:3.40.50.670 460 706 1.4E-88 T 14-10-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MB46_08005 ba303ed499d2373ee885cb710e03f402 706 SMART SM00387 36 203 2.6E-20 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MB46_08005 ba303ed499d2373ee885cb710e03f402 706 Gene3D G3DSA:3.30.230.10 257 459 1.9E-46 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MB46_08005 ba303ed499d2373ee885cb710e03f402 706 SUPERFAMILY SSF54211 258 451 1.5E-33 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MB46_08005 ba303ed499d2373ee885cb710e03f402 706 Pfam PF00204 DNA gyrase B 258 451 1.4E-49 T 14-10-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MB46_08005 ba303ed499d2373ee885cb710e03f402 706 Gene3D G3DSA:3.30.565.10 18 241 8.7E-79 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MB46_08005 ba303ed499d2373ee885cb710e03f402 706 Pfam PF01751 Toprim domain 480 587 2.8E-15 T 14-10-2018 IPR006171 TOPRIM domain MB46_08005 ba303ed499d2373ee885cb710e03f402 706 SUPERFAMILY SSF56719 455 694 6.02E-77 T 14-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 MB46_08005 ba303ed499d2373ee885cb710e03f402 706 ProSitePatterns PS00177 DNA topoisomerase II signature. 483 491 - T 14-10-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MB46_08005 ba303ed499d2373ee885cb710e03f402 706 SUPERFAMILY SSF55874 11 237 2.88E-57 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MB46_08005 ba303ed499d2373ee885cb710e03f402 706 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 635 692 3.8E-24 T 14-10-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 MB46_08005 ba303ed499d2373ee885cb710e03f402 706 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 36 143 9.3E-19 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MB46_08005 ba303ed499d2373ee885cb710e03f402 706 SMART SM00433 40 697 4.4E-255 T 14-10-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MB46_08005 ba303ed499d2373ee885cb710e03f402 706 PRINTS PR00418 DNA topoisomerase II family signature 40 55 6.8E-61 T 14-10-2018 MB46_08005 ba303ed499d2373ee885cb710e03f402 706 PRINTS PR00418 DNA topoisomerase II family signature 75 88 6.8E-61 T 14-10-2018 MB46_08005 ba303ed499d2373ee885cb710e03f402 706 PRINTS PR00418 DNA topoisomerase II family signature 118 132 6.8E-61 T 14-10-2018 MB46_08005 ba303ed499d2373ee885cb710e03f402 706 PRINTS PR00418 DNA topoisomerase II family signature 636 652 6.8E-61 T 14-10-2018 MB46_08005 ba303ed499d2373ee885cb710e03f402 706 PRINTS PR00418 DNA topoisomerase II family signature 324 337 6.8E-61 T 14-10-2018 MB46_08005 ba303ed499d2373ee885cb710e03f402 706 PRINTS PR00418 DNA topoisomerase II family signature 565 582 6.8E-61 T 14-10-2018 MB46_08005 ba303ed499d2373ee885cb710e03f402 706 PRINTS PR00418 DNA topoisomerase II family signature 481 495 6.8E-61 T 14-10-2018 MB46_08005 ba303ed499d2373ee885cb710e03f402 706 PRINTS PR00418 DNA topoisomerase II family signature 547 563 6.8E-61 T 14-10-2018 MB46_08005 ba303ed499d2373ee885cb710e03f402 706 PRINTS PR00418 DNA topoisomerase II family signature 585 597 6.8E-61 T 14-10-2018 MB46_00215 95ea3ac99e594357379046939ba8b0b3 231 SUPERFAMILY SSF63829 7 227 2.78E-47 T 14-10-2018 MB46_00215 95ea3ac99e594357379046939ba8b0b3 231 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 181 199 8.5E-29 T 14-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) MB46_00215 95ea3ac99e594357379046939ba8b0b3 231 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 75 97 8.5E-29 T 14-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) MB46_00215 95ea3ac99e594357379046939ba8b0b3 231 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 33 54 8.5E-29 T 14-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) MB46_00215 95ea3ac99e594357379046939ba8b0b3 231 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 98 118 8.5E-29 T 14-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) MB46_00215 95ea3ac99e594357379046939ba8b0b3 231 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 138 155 8.5E-29 T 14-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) MB46_00215 95ea3ac99e594357379046939ba8b0b3 231 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 4 199 1.0E-58 T 14-10-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region MB46_00215 95ea3ac99e594357379046939ba8b0b3 231 Gene3D G3DSA:2.120.10.30 1 230 3.4E-71 T 14-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like MB46_17485 fa6b7cc589e04584798bddeeb2f1b0c9 328 Gene3D G3DSA:1.10.10.10 176 227 2.5E-13 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_17485 fa6b7cc589e04584798bddeeb2f1b0c9 328 Pfam PF13404 AsnC-type helix-turn-helix domain 4 44 1.0E-9 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 MB46_17485 fa6b7cc589e04584798bddeeb2f1b0c9 328 Pfam PF13404 AsnC-type helix-turn-helix domain 179 219 8.0E-9 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 MB46_17485 fa6b7cc589e04584798bddeeb2f1b0c9 328 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 206 225 1.3E-6 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 MB46_17485 fa6b7cc589e04584798bddeeb2f1b0c9 328 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 195 206 1.3E-6 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 MB46_17485 fa6b7cc589e04584798bddeeb2f1b0c9 328 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 179 195 1.3E-6 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 MB46_17485 fa6b7cc589e04584798bddeeb2f1b0c9 328 SMART SM00344 4 109 2.5E-4 T 14-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 MB46_17485 fa6b7cc589e04584798bddeeb2f1b0c9 328 SMART SM00344 179 282 2.5E-7 T 14-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 MB46_17485 fa6b7cc589e04584798bddeeb2f1b0c9 328 Gene3D G3DSA:1.10.10.10 1 53 6.1E-14 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_17485 fa6b7cc589e04584798bddeeb2f1b0c9 328 SUPERFAMILY SSF46785 177 229 5.71E-9 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_17485 fa6b7cc589e04584798bddeeb2f1b0c9 328 SUPERFAMILY SSF46785 3 53 5.69E-6 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_09050 f547addf5d55e9057a98b083767b7393 224 Pfam PF00574 Clp protease 38 213 1.8E-73 T 14-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA MB46_09050 f547addf5d55e9057a98b083767b7393 224 SUPERFAMILY SSF52096 31 216 1.49E-62 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MB46_09050 f547addf5d55e9057a98b083767b7393 224 PRINTS PR00127 Clp protease catalytic subunit P signature 110 127 4.3E-42 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MB46_09050 f547addf5d55e9057a98b083767b7393 224 PRINTS PR00127 Clp protease catalytic subunit P signature 39 54 4.3E-42 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MB46_09050 f547addf5d55e9057a98b083767b7393 224 PRINTS PR00127 Clp protease catalytic subunit P signature 79 99 4.3E-42 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MB46_09050 f547addf5d55e9057a98b083767b7393 224 PRINTS PR00127 Clp protease catalytic subunit P signature 190 209 4.3E-42 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MB46_09050 f547addf5d55e9057a98b083767b7393 224 PRINTS PR00127 Clp protease catalytic subunit P signature 131 150 4.3E-42 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MB46_09050 f547addf5d55e9057a98b083767b7393 224 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 23 215 39.772 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MB46_09050 f547addf5d55e9057a98b083767b7393 224 Gene3D G3DSA:3.90.226.10 14 221 5.2E-75 T 14-10-2018 MB46_09050 f547addf5d55e9057a98b083767b7393 224 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 110 121 - T 14-10-2018 IPR018215 ClpP, Ser active site MB46_09050 f547addf5d55e9057a98b083767b7393 224 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 132 145 - T 14-10-2018 IPR033135 ClpP, histidine active site MB46_11560 81ca9558a9e9c9e6e6afbbd65b768036 1174 SMART SM00382 1037 1166 18.0 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_11560 81ca9558a9e9c9e6e6afbbd65b768036 1174 SMART SM00382 403 589 0.0092 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_11560 81ca9558a9e9c9e6e6afbbd65b768036 1174 SUPERFAMILY SSF52540 361 589 6.05E-25 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_11560 81ca9558a9e9c9e6e6afbbd65b768036 1174 Gene3D G3DSA:3.40.50.300 699 942 5.9E-9 T 14-10-2018 MB46_11560 81ca9558a9e9c9e6e6afbbd65b768036 1174 Gene3D G3DSA:3.40.50.300 363 646 2.4E-74 T 14-10-2018 MB46_11560 81ca9558a9e9c9e6e6afbbd65b768036 1174 Pfam PF01580 FtsK/SpoIIIE family 381 588 1.9E-27 T 14-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 MB46_00065 285285264560bd36f4902536d32928b1 464 SUPERFAMILY SSF55103 197 461 1.14E-47 T 14-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 MB46_00065 285285264560bd36f4902536d32928b1 464 SUPERFAMILY SSF56176 11 224 2.24E-69 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 MB46_00065 285285264560bd36f4902536d32928b1 464 Gene3D G3DSA:3.30.70.2740 338 419 3.6E-10 T 14-10-2018 MB46_00065 285285264560bd36f4902536d32928b1 464 Pfam PF02913 FAD linked oxidases, C-terminal domain 224 458 7.0E-48 T 14-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 MB46_00065 285285264560bd36f4902536d32928b1 464 Gene3D G3DSA:1.10.45.10 420 460 4.2E-13 T 14-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 MB46_00065 285285264560bd36f4902536d32928b1 464 Pfam PF01565 FAD binding domain 49 187 3.0E-43 T 14-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 MB46_00065 285285264560bd36f4902536d32928b1 464 Gene3D G3DSA:3.30.465.40 10 241 1.2E-72 T 14-10-2018 MB46_05860 6c11303b35039283085be02651eec3ec 100 Gene3D G3DSA:3.30.280.10 1 100 2.8E-45 T 14-10-2018 IPR036463 Urease, gamma subunit superfamily GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MB46_05860 6c11303b35039283085be02651eec3ec 100 PIRSF PIRSF001223 1 100 2.9E-49 T 14-10-2018 IPR012010 Urease, gamma subunit GO:0009039|GO:0019627 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MB46_05860 6c11303b35039283085be02651eec3ec 100 TIGRFAM TIGR00193 urease_gam: urease, gamma subunit 1 100 2.3E-46 T 14-10-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MB46_05860 6c11303b35039283085be02651eec3ec 100 ProDom PD002319 SUBUNIT GAMMA HYDROLASE UREASE UREA AMIDOHYDROLASE UREASE ALPHA GAMMA/BETA METAL-BINDING 9 99 2.0E-39 T 14-10-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MB46_05860 6c11303b35039283085be02651eec3ec 100 SUPERFAMILY SSF54111 1 100 8.89E-45 T 14-10-2018 IPR036463 Urease, gamma subunit superfamily GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MB46_05860 6c11303b35039283085be02651eec3ec 100 Hamap MF_00739 Urease subunit gamma [ureA]. 1 100 33.74 T 14-10-2018 IPR012010 Urease, gamma subunit GO:0009039|GO:0019627 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MB46_05860 6c11303b35039283085be02651eec3ec 100 Pfam PF00547 Urease, gamma subunit 1 99 6.4E-45 T 14-10-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MB46_14885 a52d988302ea32464d4bc4d0b90fad74 769 SUPERFAMILY SSF56042 219 453 8.22E-48 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily MB46_14885 a52d988302ea32464d4bc4d0b90fad74 769 Gene3D G3DSA:3.90.650.10 594 768 3.9E-35 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily MB46_14885 a52d988302ea32464d4bc4d0b90fad74 769 Gene3D G3DSA:3.30.1330.10 58 212 1.7E-119 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily MB46_14885 a52d988302ea32464d4bc4d0b90fad74 769 Gene3D G3DSA:3.90.650.10 44 385 1.7E-119 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily MB46_14885 a52d988302ea32464d4bc4d0b90fad74 769 Pfam PF00586 AIR synthase related protein, N-terminal domain 467 585 4.9E-23 T 14-10-2018 IPR016188 PurM-like, N-terminal domain MB46_14885 a52d988302ea32464d4bc4d0b90fad74 769 Pfam PF00586 AIR synthase related protein, N-terminal domain 106 208 1.2E-19 T 14-10-2018 IPR016188 PurM-like, N-terminal domain MB46_14885 a52d988302ea32464d4bc4d0b90fad74 769 Hamap MF_00420 Phosphoribosylformylglycinamidine synthase subunit PurL [purL]. 1 769 291.297 T 14-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 MB46_14885 a52d988302ea32464d4bc4d0b90fad74 769 SUPERFAMILY SSF55326 27 213 3.74E-47 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily MB46_14885 a52d988302ea32464d4bc4d0b90fad74 769 PIRSF PIRSF001587 11 769 3.8E-278 T 14-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 MB46_14885 a52d988302ea32464d4bc4d0b90fad74 769 TIGRFAM TIGR01736 FGAM_synth_II: phosphoribosylformylglycinamidine synthase II 32 767 2.9E-246 T 14-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 MB46_14885 a52d988302ea32464d4bc4d0b90fad74 769 SUPERFAMILY SSF55326 424 592 1.83E-53 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily MB46_14885 a52d988302ea32464d4bc4d0b90fad74 769 Gene3D G3DSA:3.30.1330.10 412 589 9.8E-55 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily MB46_14885 a52d988302ea32464d4bc4d0b90fad74 769 SUPERFAMILY SSF56042 596 768 1.79E-35 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily MB46_14885 a52d988302ea32464d4bc4d0b90fad74 769 Pfam PF02769 AIR synthase related protein, C-terminal domain 600 740 5.2E-19 T 14-10-2018 IPR010918 PurM-like, C-terminal domain MB46_14885 a52d988302ea32464d4bc4d0b90fad74 769 Pfam PF02769 AIR synthase related protein, C-terminal domain 221 375 2.5E-26 T 14-10-2018 IPR010918 PurM-like, C-terminal domain MB46_16730 8cb9d3ee7ab23ded42591dacabbf6f09 332 Gene3D G3DSA:1.10.3470.10 3 331 6.8E-87 T 14-10-2018 IPR037294 ABC transporter, BtuC-like MB46_16730 8cb9d3ee7ab23ded42591dacabbf6f09 332 Pfam PF01032 FecCD transport family 17 326 1.4E-81 T 14-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 MB46_16730 8cb9d3ee7ab23ded42591dacabbf6f09 332 SUPERFAMILY SSF81345 4 326 5.23E-74 T 14-10-2018 IPR037294 ABC transporter, BtuC-like MB46_10475 20ba02750083a27f477e799653a23442 158 SUPERFAMILY SSF52833 4 155 9.54E-44 T 14-10-2018 IPR036249 Thioredoxin-like superfamily MB46_10475 20ba02750083a27f477e799653a23442 158 Pfam PF00578 AhpC/TSA family 8 134 6.3E-35 T 14-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 MB46_10475 20ba02750083a27f477e799653a23442 158 PIRSF PIRSF000239 2 156 4.9E-17 T 14-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 MB46_10475 20ba02750083a27f477e799653a23442 158 Gene3D G3DSA:3.40.30.10 6 156 1.1E-43 T 14-10-2018 MB46_03210 9cd85398e6f31f43f839ca734536204b 264 SUPERFAMILY SSF52266 8 198 7.99E-38 T 14-10-2018 MB46_03210 9cd85398e6f31f43f839ca734536204b 264 Gene3D G3DSA:3.40.50.1110 11 201 7.5E-27 T 14-10-2018 IPR036514 SGNH hydrolase superfamily MB46_03210 9cd85398e6f31f43f839ca734536204b 264 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 15 188 5.6E-25 T 14-10-2018 IPR013830 SGNH hydrolase-type esterase domain MB46_04185 4b02291fc6f6be8d55653bad48d461f6 291 SUPERFAMILY SSF55945 3 97 2.98E-13 T 14-10-2018 MB46_04185 4b02291fc6f6be8d55653bad48d461f6 291 Pfam PF06029 AlkA N-terminal domain 3 116 5.4E-20 T 14-10-2018 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal MB46_04185 4b02291fc6f6be8d55653bad48d461f6 291 Gene3D G3DSA:1.10.340.30 119 230 1.2E-24 T 14-10-2018 MB46_04185 4b02291fc6f6be8d55653bad48d461f6 291 SMART SM01009 2 116 3.2E-24 T 14-10-2018 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal MB46_04185 4b02291fc6f6be8d55653bad48d461f6 291 Gene3D G3DSA:3.30.310.20 3 116 1.4E-18 T 14-10-2018 IPR037046 DNA-3-methyladenine glycosylase AlkA, N-terminal domain superfamily MB46_04185 4b02291fc6f6be8d55653bad48d461f6 291 SUPERFAMILY SSF48150 106 287 3.49E-34 T 14-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 MB46_04185 4b02291fc6f6be8d55653bad48d461f6 291 SMART SM00478 126 289 4.2E-5 T 14-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 MB46_04185 4b02291fc6f6be8d55653bad48d461f6 291 Gene3D G3DSA:1.10.1670.10 233 291 1.1E-9 T 14-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 MB46_02920 9ff0cccb45d3e3283f2a796db251599b 323 SUPERFAMILY SSF52540 14 289 1.07E-40 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_02920 9ff0cccb45d3e3283f2a796db251599b 323 Gene3D G3DSA:3.40.50.300 26 191 3.5E-43 T 14-10-2018 MB46_02920 9ff0cccb45d3e3283f2a796db251599b 323 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 45 175 5.5E-62 T 14-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 MB46_02920 9ff0cccb45d3e3283f2a796db251599b 323 Gene3D G3DSA:1.10.8.300 206 314 6.1E-28 T 14-10-2018 MB46_02920 9ff0cccb45d3e3283f2a796db251599b 323 PIRSF PIRSF002849 1 319 7.0E-129 T 14-10-2018 MB46_09095 608b9613749d841c57a7cac8f28b377c 346 Pfam PF07853 Protein of unknown function (DUF1648) 29 72 6.0E-9 T 14-10-2018 IPR012867 Domain of unknown function DUF1648 MB46_08145 6c07aa8857652a4f3b6538a04c4d11fc 312 PIRSF PIRSF000388 43 312 2.6E-100 T 14-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 MB46_08145 6c07aa8857652a4f3b6538a04c4d11fc 312 Pfam PF02548 Ketopantoate hydroxymethyltransferase 51 307 2.9E-99 T 14-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 MB46_08145 6c07aa8857652a4f3b6538a04c4d11fc 312 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 54 312 1.3E-84 T 14-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 MB46_08145 6c07aa8857652a4f3b6538a04c4d11fc 312 SUPERFAMILY SSF51621 52 311 5.5E-95 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 MB46_08145 6c07aa8857652a4f3b6538a04c4d11fc 312 Gene3D G3DSA:3.20.20.60 49 312 3.4E-99 T 14-10-2018 MB46_08145 6c07aa8857652a4f3b6538a04c4d11fc 312 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 52 312 39.853 T 14-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 MB46_15905 a39f086ebb11166499091a497b0b4c63 315 Gene3D G3DSA:3.40.50.300 1 233 1.1E-52 T 14-10-2018 MB46_15905 a39f086ebb11166499091a497b0b4c63 315 SUPERFAMILY SSF52540 2 221 6.63E-54 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_15905 a39f086ebb11166499091a497b0b4c63 315 SMART SM00382 26 204 5.8E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_15905 a39f086ebb11166499091a497b0b4c63 315 Pfam PF00005 ABC transporter 19 156 1.0E-23 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_01970 ccdddf49b5773dd2c88306feffd1e650 440 TIGRFAM TIGR02644 Y_phosphoryl: pyrimidine-nucleoside phosphorylase 14 423 1.4E-160 T 14-10-2018 IPR018090 Pyrimidine-nucleoside phosphorylase, bacterial/eukaryotic GO:0006213|GO:0016154 KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181|Reactome: R-HSA-73614|Reactome: R-HSA-73621 MB46_01970 ccdddf49b5773dd2c88306feffd1e650 440 SUPERFAMILY SSF52418 94 332 1.96E-79 T 14-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 MB46_01970 ccdddf49b5773dd2c88306feffd1e650 440 Gene3D G3DSA:3.90.1170.30 336 426 2.2E-129 T 14-10-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 MB46_01970 ccdddf49b5773dd2c88306feffd1e650 440 SUPERFAMILY SSF54680 337 439 1.44E-23 T 14-10-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 MB46_01970 ccdddf49b5773dd2c88306feffd1e650 440 Pfam PF02885 Glycosyl transferase family, helical bundle domain 14 76 3.5E-17 T 14-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 MB46_01970 ccdddf49b5773dd2c88306feffd1e650 440 SUPERFAMILY SSF47648 11 79 1.7E-19 T 14-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 MB46_01970 ccdddf49b5773dd2c88306feffd1e650 440 Gene3D G3DSA:1.20.970.10 12 77 9.1E-22 T 14-10-2018 MB46_01970 ccdddf49b5773dd2c88306feffd1e650 440 SMART SM00941 350 424 1.1E-28 T 14-10-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 MB46_01970 ccdddf49b5773dd2c88306feffd1e650 440 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 126 141 - T 14-10-2018 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 MB46_01970 ccdddf49b5773dd2c88306feffd1e650 440 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 351 424 5.4E-19 T 14-10-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 MB46_01970 ccdddf49b5773dd2c88306feffd1e650 440 Pfam PF00591 Glycosyl transferase family, a/b domain 94 304 6.3E-33 T 14-10-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 MB46_01970 ccdddf49b5773dd2c88306feffd1e650 440 PIRSF PIRSF000478 10 440 1.4E-145 T 14-10-2018 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 MB46_01970 ccdddf49b5773dd2c88306feffd1e650 440 Gene3D G3DSA:3.40.1030.10 95 335 2.2E-129 T 14-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 MB46_15955 7f3b84257ff9caac5ae7b98806a629f3 560 Pfam PF00005 ABC transporter 20 191 1.2E-19 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_15955 7f3b84257ff9caac5ae7b98806a629f3 560 SUPERFAMILY SSF52540 347 547 9.85E-30 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_15955 7f3b84257ff9caac5ae7b98806a629f3 560 Gene3D G3DSA:3.40.50.300 3 291 1.8E-43 T 14-10-2018 MB46_15955 7f3b84257ff9caac5ae7b98806a629f3 560 SUPERFAMILY SSF52540 4 235 7.14E-35 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_15955 7f3b84257ff9caac5ae7b98806a629f3 560 SMART SM00382 29 237 6.3E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_15955 7f3b84257ff9caac5ae7b98806a629f3 560 SMART SM00382 356 549 9.5E-8 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_15955 7f3b84257ff9caac5ae7b98806a629f3 560 Pfam PF00005 ABC transporter 349 496 5.4E-12 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_15955 7f3b84257ff9caac5ae7b98806a629f3 560 Gene3D G3DSA:3.40.50.300 318 560 1.6E-34 T 14-10-2018 MB46_10600 44f4acacb8db1c06fce2bcf9e9fcf7b1 447 Hamap MF_00569 Quinolinate synthase A [nadA]. 80 434 54.024 T 14-10-2018 IPR023515 Quinolinate synthase A, type 3 GO:0016765 MetaCyc: PWY-5316|MetaCyc: PWY-7342 MB46_10600 44f4acacb8db1c06fce2bcf9e9fcf7b1 447 Pfam PF02445 Quinolinate synthetase A protein 87 433 4.6E-107 T 14-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 MB46_10600 44f4acacb8db1c06fce2bcf9e9fcf7b1 447 Gene3D G3DSA:3.40.50.10800 297 383 1.5E-79 T 14-10-2018 MB46_10600 44f4acacb8db1c06fce2bcf9e9fcf7b1 447 Gene3D G3DSA:3.40.50.10800 170 432 1.5E-79 T 14-10-2018 MB46_10600 44f4acacb8db1c06fce2bcf9e9fcf7b1 447 Gene3D G3DSA:3.40.50.10800 91 415 1.5E-79 T 14-10-2018 MB46_10600 44f4acacb8db1c06fce2bcf9e9fcf7b1 447 SUPERFAMILY SSF142754 92 433 2.22E-94 T 14-10-2018 IPR036094 Quinolinate synthetase A superfamily GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 MB46_10600 44f4acacb8db1c06fce2bcf9e9fcf7b1 447 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 82 433 8.0E-92 T 14-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 MB46_15115 ba21edf6f65929297e1e010965c24d54 135 Pfam PF06262 Zincin-like metallopeptidase 41 134 5.0E-31 T 14-10-2018 IPR010428 Zincin-like metallopeptidase MB46_15115 ba21edf6f65929297e1e010965c24d54 135 Gene3D G3DSA:3.30.2010.20 14 134 7.5E-40 T 14-10-2018 IPR038555 Zincin-like metallopeptidase superfamily MB46_15115 ba21edf6f65929297e1e010965c24d54 135 SUPERFAMILY SSF55486 16 134 7.05E-31 T 14-10-2018 MB46_12645 142311839747ef81f1663e2fadd1f26c 361 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 1.7E-34 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 MB46_12645 142311839747ef81f1663e2fadd1f26c 361 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 105 1.7E-34 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 MB46_12645 142311839747ef81f1663e2fadd1f26c 361 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 1.7E-34 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 MB46_12645 142311839747ef81f1663e2fadd1f26c 361 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 70 85 1.7E-34 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 MB46_12645 142311839747ef81f1663e2fadd1f26c 361 Pfam PF01926 50S ribosome-binding GTPase 5 128 1.6E-22 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 MB46_12645 142311839747ef81f1663e2fadd1f26c 361 SUPERFAMILY SSF52540 3 299 4.11E-76 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_12645 142311839747ef81f1663e2fadd1f26c 361 Gene3D G3DSA:3.40.50.300 3 276 1.5E-138 T 14-10-2018 MB46_12645 142311839747ef81f1663e2fadd1f26c 361 SUPERFAMILY SSF81271 277 361 1.07E-34 T 14-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 MB46_12645 142311839747ef81f1663e2fadd1f26c 361 PIRSF PIRSF006641 1 361 3.1E-140 T 14-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 MB46_12645 142311839747ef81f1663e2fadd1f26c 361 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 3 361 9.2E-132 T 14-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 MB46_12645 142311839747ef81f1663e2fadd1f26c 361 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 2 361 42.17 T 14-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 MB46_12645 142311839747ef81f1663e2fadd1f26c 361 Pfam PF06071 Protein of unknown function (DUF933) 277 360 2.6E-39 T 14-10-2018 IPR013029 YchF, C-terminal domain Reactome: R-HSA-114608 MB46_12645 142311839747ef81f1663e2fadd1f26c 361 Gene3D G3DSA:3.10.20.30 48 359 1.5E-138 T 14-10-2018 IPR012675 Beta-grasp domain superfamily MB46_12645 142311839747ef81f1663e2fadd1f26c 361 Gene3D G3DSA:1.10.150.300 113 200 1.5E-138 T 14-10-2018 IPR023192 TGS-like domain superfamily Reactome: R-HSA-114608 MB46_15165 edab3de56d6245f165452c496874d0ef 576 Gene3D G3DSA:3.40.50.300 322 572 1.5E-84 T 14-10-2018 MB46_15165 edab3de56d6245f165452c496874d0ef 576 SUPERFAMILY SSF90123 8 317 4.45E-68 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MB46_15165 edab3de56d6245f165452c496874d0ef 576 Gene3D G3DSA:1.20.1560.10 2 318 1.1E-80 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MB46_15165 edab3de56d6245f165452c496874d0ef 576 Pfam PF00664 ABC transporter transmembrane region 19 288 8.9E-41 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 MB46_15165 edab3de56d6245f165452c496874d0ef 576 SMART SM00382 359 545 4.5E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_15165 edab3de56d6245f165452c496874d0ef 576 Pfam PF00005 ABC transporter 350 497 1.3E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_15165 edab3de56d6245f165452c496874d0ef 576 SUPERFAMILY SSF52540 328 569 2.51E-84 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_15165 edab3de56d6245f165452c496874d0ef 576 ProSitePatterns PS00211 ABC transporters family signature. 471 485 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_14225 93e82cbcffc0fc38a82cccd1b1c25141 367 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 5 37 5.2E-8 T 14-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 MB46_14225 93e82cbcffc0fc38a82cccd1b1c25141 367 SUPERFAMILY SSF52540 160 342 2.33E-7 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_14225 93e82cbcffc0fc38a82cccd1b1c25141 367 SUPERFAMILY SSF52374 3 146 1.34E-14 T 14-10-2018 MB46_14225 93e82cbcffc0fc38a82cccd1b1c25141 367 Gene3D G3DSA:3.40.50.620 2 156 4.4E-27 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MB46_14225 93e82cbcffc0fc38a82cccd1b1c25141 367 Gene3D G3DSA:3.40.50.300 159 338 3.7E-27 T 14-10-2018 MB46_14225 93e82cbcffc0fc38a82cccd1b1c25141 367 Pfam PF13521 AAA domain 160 334 2.9E-26 T 14-10-2018 IPR038727 NadR/Ttd14, AAA domain MB46_04425 faae9675f993a8e87ce83ed9766c764a 457 Gene3D G3DSA:1.10.3860.10 16 418 7.0E-103 T 14-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 MB46_04425 faae9675f993a8e87ce83ed9766c764a 457 PRINTS PR00173 Glutamate-aspartate symporter signature 294 320 1.6E-22 T 14-10-2018 MB46_04425 faae9675f993a8e87ce83ed9766c764a 457 PRINTS PR00173 Glutamate-aspartate symporter signature 90 115 1.6E-22 T 14-10-2018 MB46_04425 faae9675f993a8e87ce83ed9766c764a 457 PRINTS PR00173 Glutamate-aspartate symporter signature 329 348 1.6E-22 T 14-10-2018 MB46_04425 faae9675f993a8e87ce83ed9766c764a 457 PRINTS PR00173 Glutamate-aspartate symporter signature 23 43 1.6E-22 T 14-10-2018 MB46_04425 faae9675f993a8e87ce83ed9766c764a 457 Pfam PF00375 Sodium:dicarboxylate symporter family 25 403 3.1E-90 T 14-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 MB46_04425 faae9675f993a8e87ce83ed9766c764a 457 SUPERFAMILY SSF118215 25 403 4.84E-98 T 14-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 MB46_04010 33da63065ace6ff346d2303fb748463d 127 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 21 70 3.0E-14 T 14-10-2018 MB46_04010 33da63065ace6ff346d2303fb748463d 127 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 27.462 T 14-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_04010 33da63065ace6ff346d2303fb748463d 127 Pfam PF00453 Ribosomal protein L20 3 109 1.0E-41 T 14-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_04010 33da63065ace6ff346d2303fb748463d 127 SUPERFAMILY SSF74731 3 117 1.83E-43 T 14-10-2018 IPR035566 Ribosomal protein L20, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_04010 33da63065ace6ff346d2303fb748463d 127 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 14-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_04010 33da63065ace6ff346d2303fb748463d 127 Gene3D G3DSA:1.10.720.90 2 55 6.2E-18 T 14-10-2018 MB46_04010 33da63065ace6ff346d2303fb748463d 127 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 2 114 1.2E-41 T 14-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_04010 33da63065ace6ff346d2303fb748463d 127 PRINTS PR00062 Ribosomal protein L20 signature 42 71 1.1E-35 T 14-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_04010 33da63065ace6ff346d2303fb748463d 127 PRINTS PR00062 Ribosomal protein L20 signature 75 101 1.1E-35 T 14-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_04010 33da63065ace6ff346d2303fb748463d 127 PRINTS PR00062 Ribosomal protein L20 signature 12 41 1.1E-35 T 14-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_04010 33da63065ace6ff346d2303fb748463d 127 Gene3D G3DSA:1.10.1900.20 56 119 3.7E-26 T 14-10-2018 IPR035566 Ribosomal protein L20, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_01440 3891c6a97aba99f70eefd5c53bd34438 234 SMART SM00345 10 69 4.3E-21 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MB46_01440 3891c6a97aba99f70eefd5c53bd34438 234 Gene3D G3DSA:1.20.120.530 94 228 3.3E-28 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MB46_01440 3891c6a97aba99f70eefd5c53bd34438 234 SMART SM00895 97 221 1.4E-22 T 14-10-2018 IPR011711 GntR, C-terminal MB46_01440 3891c6a97aba99f70eefd5c53bd34438 234 Pfam PF07729 FCD domain 97 220 2.0E-24 T 14-10-2018 IPR011711 GntR, C-terminal MB46_01440 3891c6a97aba99f70eefd5c53bd34438 234 Pfam PF00392 Bacterial regulatory proteins, gntR family 7 69 2.3E-17 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MB46_01440 3891c6a97aba99f70eefd5c53bd34438 234 SUPERFAMILY SSF46785 3 73 4.48E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_01440 3891c6a97aba99f70eefd5c53bd34438 234 Gene3D G3DSA:1.10.10.10 1 72 3.2E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_01440 3891c6a97aba99f70eefd5c53bd34438 234 SUPERFAMILY SSF48008 96 227 8.63E-28 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MB46_01440 3891c6a97aba99f70eefd5c53bd34438 234 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 43 59 3.5E-6 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MB46_01440 3891c6a97aba99f70eefd5c53bd34438 234 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 29 43 3.5E-6 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MB46_13340 f3dc84534fd41a276f54c5be040da208 441 Gene3D G3DSA:1.10.3370.10 1 436 3.2E-156 T 14-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 MB46_13340 f3dc84534fd41a276f54c5be040da208 441 ProSitePatterns PS00756 Protein secY signature 2. 179 196 - T 14-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 MB46_13340 f3dc84534fd41a276f54c5be040da208 441 ProSitePatterns PS00755 Protein secY signature 1. 73 92 - T 14-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 MB46_13340 f3dc84534fd41a276f54c5be040da208 441 Pfam PF00344 SecY translocase 73 424 3.4E-113 T 14-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 MB46_13340 f3dc84534fd41a276f54c5be040da208 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 18 36 1.3E-99 T 14-10-2018 MB46_13340 f3dc84534fd41a276f54c5be040da208 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 160 185 1.3E-99 T 14-10-2018 MB46_13340 f3dc84534fd41a276f54c5be040da208 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 72 92 1.3E-99 T 14-10-2018 MB46_13340 f3dc84534fd41a276f54c5be040da208 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 409 427 1.3E-99 T 14-10-2018 MB46_13340 f3dc84534fd41a276f54c5be040da208 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 375 393 1.3E-99 T 14-10-2018 MB46_13340 f3dc84534fd41a276f54c5be040da208 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 273 292 1.3E-99 T 14-10-2018 MB46_13340 f3dc84534fd41a276f54c5be040da208 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 113 136 1.3E-99 T 14-10-2018 MB46_13340 f3dc84534fd41a276f54c5be040da208 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 186 209 1.3E-99 T 14-10-2018 MB46_13340 f3dc84534fd41a276f54c5be040da208 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 320 342 1.3E-99 T 14-10-2018 MB46_13340 f3dc84534fd41a276f54c5be040da208 441 PIRSF PIRSF004557 1 441 1.3E-115 T 14-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 MB46_13340 f3dc84534fd41a276f54c5be040da208 441 Hamap MF_01465 Protein translocase subunit SecY [secY]. 5 440 28.338 T 14-10-2018 IPR026593 Protein translocase subunit SecY MB46_13340 f3dc84534fd41a276f54c5be040da208 441 SUPERFAMILY SSF103491 3 431 4.05E-121 T 14-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 MB46_13340 f3dc84534fd41a276f54c5be040da208 441 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 15 436 9.4E-130 T 14-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 MB46_13220 8d380b8f71d69d16cecfe1686438b17d 706 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 10 96 3.4E-19 T 14-10-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 MB46_13220 8d380b8f71d69d16cecfe1686438b17d 706 SUPERFAMILY SSF51011 596 702 9.56E-22 T 14-10-2018 MB46_13220 8d380b8f71d69d16cecfe1686438b17d 706 Gene3D G3DSA:3.20.20.80 137 585 6.5E-180 T 14-10-2018 MB46_13220 8d380b8f71d69d16cecfe1686438b17d 706 SUPERFAMILY SSF81296 5 143 4.8E-44 T 14-10-2018 IPR014756 Immunoglobulin E-set MB46_13220 8d380b8f71d69d16cecfe1686438b17d 706 TIGRFAM TIGR02100 glgX_debranch: glycogen debranching enzyme GlgX 6 701 1.1E-294 T 14-10-2018 IPR011837 Glycogen debranching enzyme, GlgX type GO:0004133|GO:0004553|GO:0005980 MB46_13220 8d380b8f71d69d16cecfe1686438b17d 706 SUPERFAMILY SSF51445 133 579 2.86E-128 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily MB46_13220 8d380b8f71d69d16cecfe1686438b17d 706 Gene3D G3DSA:2.60.40.1180 595 702 2.5E-13 T 14-10-2018 IPR013780 Glycosyl hydrolase, all-beta MB46_13220 8d380b8f71d69d16cecfe1686438b17d 706 Pfam PF00128 Alpha amylase, catalytic domain 194 535 8.3E-12 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MB46_13220 8d380b8f71d69d16cecfe1686438b17d 706 SMART SM00642 133 571 5.2E-7 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MB46_13220 8d380b8f71d69d16cecfe1686438b17d 706 Gene3D G3DSA:2.60.40.10 1 136 3.5E-45 T 14-10-2018 IPR013783 Immunoglobulin-like fold MB46_13900 d42c3dc6d883ce41664f3a28128e6db2 149 SUPERFAMILY SSF46689 62 110 2.46E-7 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MB46_13900 d42c3dc6d883ce41664f3a28128e6db2 149 SMART SM00342 26 108 9.7E-25 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MB46_13900 d42c3dc6d883ce41664f3a28128e6db2 149 SUPERFAMILY SSF46689 11 60 1.61E-10 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MB46_13900 d42c3dc6d883ce41664f3a28128e6db2 149 Pfam PF12833 Helix-turn-helix domain 32 110 8.4E-20 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MB46_13900 d42c3dc6d883ce41664f3a28128e6db2 149 Gene3D G3DSA:1.10.10.60 7 114 1.8E-25 T 14-10-2018 MB46_10740 bcf39d65bb092d6102eb7918d1f83ed6 188 Pfam PF09438 Domain of unknown function (DUF2017) 10 180 1.1E-48 T 14-10-2018 IPR018561 Domain of unknown function DUF2017 MB46_17845 fc8ee1e0afb0ff89c71a49bd1e797e69 262 PIRSF PIRSF030013 9 249 2.6E-106 T 14-10-2018 IPR009381 Trehalose catabolism protein, ThuA, prokaryote MB46_17845 fc8ee1e0afb0ff89c71a49bd1e797e69 262 Gene3D G3DSA:3.40.50.880 5 249 4.6E-99 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like MB46_17845 fc8ee1e0afb0ff89c71a49bd1e797e69 262 SUPERFAMILY SSF52317 10 234 1.19E-59 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like MB46_17845 fc8ee1e0afb0ff89c71a49bd1e797e69 262 Pfam PF06283 Trehalose utilisation 12 230 1.5E-33 T 14-10-2018 IPR029010 ThuA-like domain MB46_13020 cf35b5ff1cb48082cb3b6df8c6748c17 503 PIRSF PIRSF000130 5 503 2.4E-198 T 14-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 MB46_13020 cf35b5ff1cb48082cb3b6df8c6748c17 503 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 305 317 - T 14-10-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 MB46_13020 cf35b5ff1cb48082cb3b6df8c6748c17 503 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 14 471 5.2E-177 T 14-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 MB46_13020 cf35b5ff1cb48082cb3b6df8c6748c17 503 SMART SM01240 13 490 6.1E-298 T 14-10-2018 MB46_13020 cf35b5ff1cb48082cb3b6df8c6748c17 503 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 14 503 81.819 T 14-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 MB46_13020 cf35b5ff1cb48082cb3b6df8c6748c17 503 Pfam PF00571 CBS domain 158 212 3.8E-4 T 14-10-2018 IPR000644 CBS domain MB46_13020 cf35b5ff1cb48082cb3b6df8c6748c17 503 Pfam PF00571 CBS domain 99 144 9.3E-8 T 14-10-2018 IPR000644 CBS domain MB46_13020 cf35b5ff1cb48082cb3b6df8c6748c17 503 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 14 490 7.4E-152 T 14-10-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 MB46_13020 cf35b5ff1cb48082cb3b6df8c6748c17 503 Gene3D G3DSA:3.20.20.70 7 503 4.2E-201 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MB46_13020 cf35b5ff1cb48082cb3b6df8c6748c17 503 SMART SM00116 166 214 7.3E-6 T 14-10-2018 IPR000644 CBS domain MB46_13020 cf35b5ff1cb48082cb3b6df8c6748c17 503 SMART SM00116 102 150 8.9E-4 T 14-10-2018 IPR000644 CBS domain MB46_13020 cf35b5ff1cb48082cb3b6df8c6748c17 503 SUPERFAMILY SSF51412 11 494 1.44E-113 T 14-10-2018 MB46_13020 cf35b5ff1cb48082cb3b6df8c6748c17 503 SUPERFAMILY SSF54631 70 212 4.3E-28 T 14-10-2018 MB46_03255 969b49e64f063a2786fc750e77bb3b2a 243 Pfam PF13649 Methyltransferase domain 72 158 1.5E-12 T 14-10-2018 MB46_03255 969b49e64f063a2786fc750e77bb3b2a 243 Gene3D G3DSA:3.40.50.150 32 233 1.0E-18 T 14-10-2018 MB46_03255 969b49e64f063a2786fc750e77bb3b2a 243 SUPERFAMILY SSF53335 35 160 1.72E-18 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MB46_18995 e57d3320a79563cbeb731bd185b495fd 187 Pfam PF00440 Bacterial regulatory proteins, tetR family 7 51 5.1E-11 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MB46_18995 e57d3320a79563cbeb731bd185b495fd 187 Gene3D G3DSA:1.10.357.10 3 187 6.0E-25 T 14-10-2018 MB46_18995 e57d3320a79563cbeb731bd185b495fd 187 SUPERFAMILY SSF46689 4 66 8.21E-12 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MB46_08845 929424a8ecb0500d28eb06b370fb16d0 771 Pfam PF08267 Cobalamin-independent synthase, N-terminal domain 11 327 8.2E-97 T 14-10-2018 IPR013215 Cobalamin-independent methionine synthase MetE, N-terminal GO:0003871|GO:0008270|GO:0008652 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 MB46_08845 929424a8ecb0500d28eb06b370fb16d0 771 Gene3D G3DSA:3.20.20.210 12 535 0.0 T 14-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 MB46_08845 929424a8ecb0500d28eb06b370fb16d0 771 PIRSF PIRSF000382 7 771 6.1E-292 T 14-10-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 MB46_08845 929424a8ecb0500d28eb06b370fb16d0 771 TIGRFAM TIGR01371 met_syn_B12ind: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase 13 769 5.6E-294 T 14-10-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 MB46_08845 929424a8ecb0500d28eb06b370fb16d0 771 Gene3D G3DSA:3.20.20.210 401 767 0.0 T 14-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 MB46_08845 929424a8ecb0500d28eb06b370fb16d0 771 SUPERFAMILY SSF51726 408 769 1.83E-107 T 14-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 MB46_08845 929424a8ecb0500d28eb06b370fb16d0 771 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 442 764 4.3E-140 T 14-10-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 MB46_08845 929424a8ecb0500d28eb06b370fb16d0 771 SUPERFAMILY SSF51726 11 401 2.75E-83 T 14-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 MB46_19625 9bc43c0cd0da35e60d5868a1407378d9 98 Gene3D G3DSA:1.10.10.60 20 98 4.5E-8 T 14-10-2018 MB46_07935 2fcc4e764ad2f083b56146745094b1bf 101 Pfam PF13834 Domain of unknown function (DUF4193) 1 100 2.3E-23 T 14-10-2018 IPR025242 Protein of unknown function DUF4193 MB46_09670 da4017ab3c91fcfdd1f6f60e5d6abe7f 409 Pfam PF07690 Major Facilitator Superfamily 27 231 5.5E-32 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MB46_09670 da4017ab3c91fcfdd1f6f60e5d6abe7f 409 Gene3D G3DSA:1.20.1250.20 222 407 8.1E-26 T 14-10-2018 MB46_09670 da4017ab3c91fcfdd1f6f60e5d6abe7f 409 PRINTS PR01035 Tetracycline resistance protein signature 32 48 8.4E-15 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MB46_09670 da4017ab3c91fcfdd1f6f60e5d6abe7f 409 PRINTS PR01035 Tetracycline resistance protein signature 147 169 8.4E-15 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MB46_09670 da4017ab3c91fcfdd1f6f60e5d6abe7f 409 PRINTS PR01035 Tetracycline resistance protein signature 260 280 8.4E-15 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MB46_09670 da4017ab3c91fcfdd1f6f60e5d6abe7f 409 PRINTS PR01035 Tetracycline resistance protein signature 313 333 8.4E-15 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MB46_09670 da4017ab3c91fcfdd1f6f60e5d6abe7f 409 PRINTS PR01035 Tetracycline resistance protein signature 349 372 8.4E-15 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MB46_09670 da4017ab3c91fcfdd1f6f60e5d6abe7f 409 PRINTS PR01035 Tetracycline resistance protein signature 175 195 8.4E-15 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MB46_09670 da4017ab3c91fcfdd1f6f60e5d6abe7f 409 Gene3D G3DSA:1.20.1250.20 23 219 2.6E-34 T 14-10-2018 MB46_09670 da4017ab3c91fcfdd1f6f60e5d6abe7f 409 SUPERFAMILY SSF103473 20 399 1.96E-71 T 14-10-2018 IPR036259 MFS transporter superfamily MB46_16700 66844cac36d0a1be68c20c03f5d9cb9e 225 Gene3D G3DSA:1.10.3720.10 8 205 3.2E-24 T 14-10-2018 IPR035906 MetI-like superfamily MB46_16700 66844cac36d0a1be68c20c03f5d9cb9e 225 SUPERFAMILY SSF161098 10 195 5.89E-29 T 14-10-2018 IPR035906 MetI-like superfamily MB46_16700 66844cac36d0a1be68c20c03f5d9cb9e 225 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 30 209 1.1E-17 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_02180 9baa4ebb3013b6c0243b382fde1a66cb 557 PRINTS PR01036 Tetracycline resistance protein TetB signature 209 227 4.3E-8 T 14-10-2018 MB46_02180 9baa4ebb3013b6c0243b382fde1a66cb 557 PRINTS PR01036 Tetracycline resistance protein TetB signature 114 134 4.3E-8 T 14-10-2018 MB46_02180 9baa4ebb3013b6c0243b382fde1a66cb 557 PRINTS PR01036 Tetracycline resistance protein TetB signature 408 427 4.3E-8 T 14-10-2018 MB46_02180 9baa4ebb3013b6c0243b382fde1a66cb 557 PRINTS PR01036 Tetracycline resistance protein TetB signature 24 48 4.3E-8 T 14-10-2018 MB46_02180 9baa4ebb3013b6c0243b382fde1a66cb 557 PRINTS PR01036 Tetracycline resistance protein TetB signature 144 168 4.3E-8 T 14-10-2018 MB46_02180 9baa4ebb3013b6c0243b382fde1a66cb 557 Gene3D G3DSA:1.20.1720.10 22 228 3.9E-51 T 14-10-2018 MB46_02180 9baa4ebb3013b6c0243b382fde1a66cb 557 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 21 498 1.6E-82 T 14-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 MB46_02180 9baa4ebb3013b6c0243b382fde1a66cb 557 SUPERFAMILY SSF103473 11 500 8.11E-70 T 14-10-2018 IPR036259 MFS transporter superfamily MB46_02180 9baa4ebb3013b6c0243b382fde1a66cb 557 Pfam PF07690 Major Facilitator Superfamily 26 417 3.8E-57 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MB46_08970 b9908a83d9cbb43c8c2a372198b06626 525 Gene3D G3DSA:3.40.1190.20 14 304 6.1E-90 T 14-10-2018 IPR029056 Ribokinase-like MB46_08970 b9908a83d9cbb43c8c2a372198b06626 525 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 36 291 3.6E-76 T 14-10-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 MB46_08970 b9908a83d9cbb43c8c2a372198b06626 525 SUPERFAMILY SSF48613 304 510 4.9E-54 T 14-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 MB46_08970 b9908a83d9cbb43c8c2a372198b06626 525 Pfam PF08543 Phosphomethylpyrimidine kinase 43 290 5.7E-78 T 14-10-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 MB46_08970 b9908a83d9cbb43c8c2a372198b06626 525 SUPERFAMILY SSF53613 32 296 1.56E-69 T 14-10-2018 IPR029056 Ribokinase-like MB46_08970 b9908a83d9cbb43c8c2a372198b06626 525 Pfam PF03070 TENA/THI-4/PQQC family 325 510 1.3E-27 T 14-10-2018 IPR004305 Thiaminase-2/PQQC MB46_08970 b9908a83d9cbb43c8c2a372198b06626 525 Gene3D G3DSA:1.20.910.10 305 512 1.1E-53 T 14-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 MB46_14940 5acf9eae8917cd86eef706eec4813987 340 TIGRFAM TIGR01520 FruBisAldo_II_A: fructose-bisphosphate aldolase, class II 3 336 1.7E-123 T 14-10-2018 IPR006411 Fructose-bisphosphate aldolase, class II, yeast/E. coli subtype GO:0004332|GO:0006096 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 MB46_14940 5acf9eae8917cd86eef706eec4813987 340 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 158 169 - T 14-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 MB46_14940 5acf9eae8917cd86eef706eec4813987 340 SUPERFAMILY SSF51569 3 337 7.91E-93 T 14-10-2018 MB46_14940 5acf9eae8917cd86eef706eec4813987 340 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 9 337 6.7E-68 T 14-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 MB46_14940 5acf9eae8917cd86eef706eec4813987 340 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 86 97 - T 14-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 MB46_14940 5acf9eae8917cd86eef706eec4813987 340 Gene3D G3DSA:3.20.20.70 1 340 2.4E-117 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MB46_14940 5acf9eae8917cd86eef706eec4813987 340 PIRSF PIRSF001359 5 338 4.7E-62 T 14-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 MB46_14940 5acf9eae8917cd86eef706eec4813987 340 Pfam PF01116 Fructose-bisphosphate aldolase class-II 8 337 1.6E-77 T 14-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 MB46_12050 caae250450fff9be0186e6f93deb4f72 505 Gene3D G3DSA:3.50.50.60 20 489 2.9E-94 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_12050 caae250450fff9be0186e6f93deb4f72 505 TIGRFAM TIGR00562 proto_IX_ox: protoporphyrinogen oxidase 18 494 1.5E-29 T 14-10-2018 IPR004572 Protoporphyrinogen oxidase GO:0004729|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.4|MetaCyc: PWY-7159|Reactome: R-HSA-189451 MB46_12050 caae250450fff9be0186e6f93deb4f72 505 Gene3D G3DSA:3.90.660.20 49 449 2.9E-94 T 14-10-2018 MB46_12050 caae250450fff9be0186e6f93deb4f72 505 Gene3D G3DSA:1.10.3110.10 116 210 2.9E-94 T 14-10-2018 MB46_12050 caae250450fff9be0186e6f93deb4f72 505 Pfam PF01593 Flavin containing amine oxidoreductase 26 489 1.8E-16 T 14-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 MB46_12050 caae250450fff9be0186e6f93deb4f72 505 SUPERFAMILY SSF54373 331 449 4.12E-11 T 14-10-2018 MB46_12050 caae250450fff9be0186e6f93deb4f72 505 SUPERFAMILY SSF51905 18 489 1.1E-35 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_05845 864b10fb57293df41b88bad7699a896f 164 SUPERFAMILY SSF69737 86 159 1.02E-14 T 14-10-2018 IPR036675 UreE, C-terminal domain superfamily GO:0016151|GO:0019627|GO:0065003 MB46_05845 864b10fb57293df41b88bad7699a896f 164 SMART SM00988 11 79 5.9E-11 T 14-10-2018 IPR004029 UreE urease accessory, N-terminal MB46_05845 864b10fb57293df41b88bad7699a896f 164 Pfam PF02814 UreE urease accessory protein, N-terminal domain 26 76 4.8E-14 T 14-10-2018 IPR004029 UreE urease accessory, N-terminal MB46_05845 864b10fb57293df41b88bad7699a896f 164 Gene3D G3DSA:3.30.70.790 84 164 2.3E-30 T 14-10-2018 IPR036675 UreE, C-terminal domain superfamily GO:0016151|GO:0019627|GO:0065003 MB46_05845 864b10fb57293df41b88bad7699a896f 164 SUPERFAMILY SSF69287 17 83 1.57E-14 T 14-10-2018 IPR036118 UreE urease accessory, N-terminal domain superfamily MB46_05845 864b10fb57293df41b88bad7699a896f 164 PIRSF PIRSF036402 1 164 3.7E-42 T 14-10-2018 IPR012406 Urease accessory protein UreE GO:0005737|GO:0006457|GO:0016151|GO:0018307 MB46_05845 864b10fb57293df41b88bad7699a896f 164 Hamap MF_00822 Urease accessory protein UreE [ureE]. 1 164 20.367 T 14-10-2018 IPR012406 Urease accessory protein UreE GO:0005737|GO:0006457|GO:0016151|GO:0018307 MB46_05845 864b10fb57293df41b88bad7699a896f 164 Pfam PF05194 UreE urease accessory protein, C-terminal domain 87 151 2.3E-5 T 14-10-2018 IPR007864 Urease accessory protein UreE, C-terminal domain GO:0016151|GO:0019627|GO:0065003 MB46_05845 864b10fb57293df41b88bad7699a896f 164 Gene3D G3DSA:2.60.260.20 1 83 6.8E-14 T 14-10-2018 MB46_15320 47aa77b0ec024b29517c01e7687e92cd 259 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_15320 47aa77b0ec024b29517c01e7687e92cd 259 SUPERFAMILY SSF52540 5 245 9.13E-56 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_15320 47aa77b0ec024b29517c01e7687e92cd 259 Gene3D G3DSA:3.40.50.300 2 257 4.0E-62 T 14-10-2018 MB46_15320 47aa77b0ec024b29517c01e7687e92cd 259 Pfam PF00005 ABC transporter 21 177 7.8E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_15320 47aa77b0ec024b29517c01e7687e92cd 259 SMART SM00382 29 230 2.6E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_15320 47aa77b0ec024b29517c01e7687e92cd 259 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 5 259 1.5E-111 T 14-10-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 MB46_00750 32148c6a02dd703a14da83bb852a7264 263 ProSitePatterns PS00211 ABC transporters family signature. 151 165 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_00750 32148c6a02dd703a14da83bb852a7264 263 SMART SM00382 36 228 9.4E-19 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_00750 32148c6a02dd703a14da83bb852a7264 263 Pfam PF00005 ABC transporter 28 178 7.1E-35 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_00750 32148c6a02dd703a14da83bb852a7264 263 SUPERFAMILY SSF52540 4 249 2.17E-69 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_00750 32148c6a02dd703a14da83bb852a7264 263 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 230 260 3.1E-7 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MB46_00750 32148c6a02dd703a14da83bb852a7264 263 Gene3D G3DSA:3.40.50.300 2 263 5.6E-85 T 14-10-2018 MB46_14775 07a85a5945044ef55a7e89252dff6ca2 913 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 148 309 5.3E-10 T 14-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 MB46_14775 07a85a5945044ef55a7e89252dff6ca2 913 Gene3D G3DSA:3.40.50.920 727 904 1.1E-67 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 MB46_14775 07a85a5945044ef55a7e89252dff6ca2 913 PIRSF PIRSF000156 9 907 0.0 T 14-10-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 MB46_14775 07a85a5945044ef55a7e89252dff6ca2 913 SUPERFAMILY SSF52922 723 898 1.71E-56 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 MB46_14775 07a85a5945044ef55a7e89252dff6ca2 913 Gene3D G3DSA:3.40.50.970 489 725 3.3E-100 T 14-10-2018 MB46_14775 07a85a5945044ef55a7e89252dff6ca2 913 SUPERFAMILY SSF52518 69 485 6.8E-129 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold MB46_14775 07a85a5945044ef55a7e89252dff6ca2 913 Gene3D G3DSA:3.40.50.970 68 488 1.7E-132 T 14-10-2018 MB46_14775 07a85a5945044ef55a7e89252dff6ca2 913 SUPERFAMILY SSF52518 490 719 2.0E-84 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold MB46_14775 07a85a5945044ef55a7e89252dff6ca2 913 TIGRFAM TIGR00759 aceE: pyruvate dehydrogenase (acetyl-transferring), homodimeric type 18 900 0.0 T 14-10-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 MB46_08260 69c57db73bb902edee2391454862d071 501 Pfam PF01225 Mur ligase family, catalytic domain 31 76 3.8E-6 T 14-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 MB46_08260 69c57db73bb902edee2391454862d071 501 Gene3D G3DSA:3.40.1390.10 1 88 1.2E-17 T 14-10-2018 MB46_08260 69c57db73bb902edee2391454862d071 501 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 34 471 1.5E-107 T 14-10-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MB46_08260 69c57db73bb902edee2391454862d071 501 SUPERFAMILY SSF53623 114 331 1.06E-46 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 MB46_08260 69c57db73bb902edee2391454862d071 501 Gene3D G3DSA:3.90.190.20 335 482 4.7E-34 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MB46_08260 69c57db73bb902edee2391454862d071 501 Gene3D G3DSA:3.40.1190.10 91 332 3.5E-63 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 MB46_08260 69c57db73bb902edee2391454862d071 501 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 4 479 29.328 T 14-10-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MB46_08260 69c57db73bb902edee2391454862d071 501 Pfam PF08245 Mur ligase middle domain 119 315 2.5E-38 T 14-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 MB46_08260 69c57db73bb902edee2391454862d071 501 Pfam PF02875 Mur ligase family, glutamate ligase domain 339 424 2.2E-20 T 14-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 MB46_08260 69c57db73bb902edee2391454862d071 501 SUPERFAMILY SSF63418 3 105 8.63E-18 T 14-10-2018 IPR035911 MurE/MurF, N-terminal MB46_08260 69c57db73bb902edee2391454862d071 501 SUPERFAMILY SSF53244 338 472 7.14E-31 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MB46_16965 29d012766778e1058efa99b0ddd40bb7 86 Pfam PF14019 Protein of unknown function (DUF4235) 6 80 1.2E-21 T 14-10-2018 IPR025329 Protein of unknown function DUF4235 MB46_08225 81bc3276e1e1a52256af4e8cec12b507 389 PRINTS PR00423 Cell division protein FtsZ signature 186 208 1.4E-50 T 14-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 MB46_08225 81bc3276e1e1a52256af4e8cec12b507 389 PRINTS PR00423 Cell division protein FtsZ signature 123 144 1.4E-50 T 14-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 MB46_08225 81bc3276e1e1a52256af4e8cec12b507 389 PRINTS PR00423 Cell division protein FtsZ signature 95 115 1.4E-50 T 14-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 MB46_08225 81bc3276e1e1a52256af4e8cec12b507 389 PRINTS PR00423 Cell division protein FtsZ signature 209 230 1.4E-50 T 14-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 MB46_08225 81bc3276e1e1a52256af4e8cec12b507 389 Gene3D G3DSA:3.30.1330.20 218 328 2.5E-38 T 14-10-2018 IPR037103 Tubulin/FtsZ, C-terminal domain superfamily Reactome: R-HSA-380320 MB46_08225 81bc3276e1e1a52256af4e8cec12b507 389 Pfam PF12327 FtsZ family, C-terminal domain 219 313 3.0E-34 T 14-10-2018 IPR024757 Cell division protein FtsZ, C-terminal MB46_08225 81bc3276e1e1a52256af4e8cec12b507 389 SMART SM00865 204 321 2.9E-55 T 14-10-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-380320 MB46_08225 81bc3276e1e1a52256af4e8cec12b507 389 SMART SM00864 10 202 3.4E-107 T 14-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 MB46_08225 81bc3276e1e1a52256af4e8cec12b507 389 SUPERFAMILY SSF52490 9 205 9.29E-67 T 14-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 MB46_08225 81bc3276e1e1a52256af4e8cec12b507 389 Gene3D G3DSA:3.40.50.1440 1 217 5.6E-80 T 14-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 MB46_08225 81bc3276e1e1a52256af4e8cec12b507 389 ProSitePatterns PS01134 FtsZ protein signature 1. 41 75 - T 14-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 MB46_08225 81bc3276e1e1a52256af4e8cec12b507 389 SUPERFAMILY SSF55307 201 315 7.33E-43 T 14-10-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 MB46_08225 81bc3276e1e1a52256af4e8cec12b507 389 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 7 319 9.2E-126 T 14-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 MB46_08225 81bc3276e1e1a52256af4e8cec12b507 389 ProSitePatterns PS01135 FtsZ protein signature 2. 94 115 - T 14-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 MB46_08225 81bc3276e1e1a52256af4e8cec12b507 389 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 11 170 7.1E-37 T 14-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 MB46_08225 81bc3276e1e1a52256af4e8cec12b507 389 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 6 326 38.448 T 14-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 MB46_17135 09a9fbed005fd6e7cf7772f0d30915a2 272 Pfam PF02390 Putative methyltransferase 70 213 8.0E-46 T 14-10-2018 MB46_17135 09a9fbed005fd6e7cf7772f0d30915a2 272 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 20 272 28.855 T 14-10-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 MB46_17135 09a9fbed005fd6e7cf7772f0d30915a2 272 Gene3D G3DSA:3.40.50.150 29 272 2.4E-62 T 14-10-2018 MB46_17135 09a9fbed005fd6e7cf7772f0d30915a2 272 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 63 271 2.6E-44 T 14-10-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 MB46_17135 09a9fbed005fd6e7cf7772f0d30915a2 272 SUPERFAMILY SSF53335 57 270 1.14E-26 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MB46_03780 e103c2753f246bb8004ce18572914b85 291 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 4 274 13.19 T 14-10-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 MB46_03780 e103c2753f246bb8004ce18572914b85 291 Gene3D G3DSA:2.30.130.10 206 274 7.7E-10 T 14-10-2018 IPR036974 PUA domain superfamily GO:0003723 MB46_03780 e103c2753f246bb8004ce18572914b85 291 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 160 217 8.4E-12 T 14-10-2018 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 MB46_03780 e103c2753f246bb8004ce18572914b85 291 SUPERFAMILY SSF55120 2 203 3.17E-61 T 14-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 MB46_03780 e103c2753f246bb8004ce18572914b85 291 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 2 159 2.8E-51 T 14-10-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 MB46_03780 e103c2753f246bb8004ce18572914b85 291 SUPERFAMILY SSF88697 215 276 4.72E-10 T 14-10-2018 IPR015947 PUA-like superfamily MB46_03780 e103c2753f246bb8004ce18572914b85 291 Pfam PF09142 tRNA Pseudouridine synthase II, C terminal 215 275 5.1E-19 T 14-10-2018 IPR015225 tRNA pseudouridine synthase II, TruB, subfamily 2, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 MB46_03780 e103c2753f246bb8004ce18572914b85 291 Gene3D G3DSA:3.30.2350.10 1 205 3.7E-77 T 14-10-2018 MB46_03780 e103c2753f246bb8004ce18572914b85 291 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 1 198 1.6E-58 T 14-10-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 MB46_00675 53ea773b7f069731aa9c85d9da5afbaf 552 ProDom PD141294 TRANSMEMBRANE MEMBRANE PROTEIN GTRIV-SF YFDI PREDICTED 61 393 4.0E-14 T 14-10-2018 MB46_18340 e1a7250f9821d4fba88f9d3ad2ac95b2 401 SUPERFAMILY SSF55031 180 286 1.07E-21 T 14-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain MB46_18340 e1a7250f9821d4fba88f9d3ad2ac95b2 401 PIRSF PIRSF037226 7 400 5.6E-117 T 14-10-2018 IPR017144 Peptidase M20A, amidohydrolase, predicted MB46_18340 e1a7250f9821d4fba88f9d3ad2ac95b2 401 Pfam PF01546 Peptidase family M20/M25/M40 99 371 1.3E-7 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 MB46_18340 e1a7250f9821d4fba88f9d3ad2ac95b2 401 Gene3D G3DSA:3.30.70.360 178 295 6.7E-115 T 14-10-2018 MB46_18340 e1a7250f9821d4fba88f9d3ad2ac95b2 401 Gene3D G3DSA:3.40.630.10 31 372 6.7E-115 T 14-10-2018 MB46_18340 e1a7250f9821d4fba88f9d3ad2ac95b2 401 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 31 355 8.3E-60 T 14-10-2018 IPR017439 Amidohydrolase GO:0016787 MB46_18340 e1a7250f9821d4fba88f9d3ad2ac95b2 401 Pfam PF07687 Peptidase dimerisation domain 181 258 6.1E-8 T 14-10-2018 IPR011650 Peptidase M20, dimerisation domain MB46_18340 e1a7250f9821d4fba88f9d3ad2ac95b2 401 SUPERFAMILY SSF53187 22 381 5.91E-56 T 14-10-2018 MB46_06090 05657b0fe82f3aedda2525d66b9782b3 505 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 82 411 4.7E-85 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain MB46_06090 05657b0fe82f3aedda2525d66b9782b3 505 SUPERFAMILY SSF53850 34 504 3.12E-112 T 14-10-2018 MB46_06090 05657b0fe82f3aedda2525d66b9782b3 505 Gene3D G3DSA:3.10.105.10 272 467 1.8E-100 T 14-10-2018 MB46_06090 05657b0fe82f3aedda2525d66b9782b3 505 PIRSF PIRSF002741 1 502 1.1E-87 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 MB46_06090 05657b0fe82f3aedda2525d66b9782b3 505 Gene3D G3DSA:3.40.190.10 66 271 1.8E-100 T 14-10-2018 MB46_10735 e3fed882dc5db3254c6854d5e2a5327c 344 SUPERFAMILY SSF53681 133 284 1.11E-37 T 14-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MB46_10735 e3fed882dc5db3254c6854d5e2a5327c 344 Hamap MF_00258 Glutamate racemase [murI]. 24 279 35.505 T 14-10-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MB46_10735 e3fed882dc5db3254c6854d5e2a5327c 344 Pfam PF01177 Asp/Glu/Hydantoin racemase 26 237 2.4E-29 T 14-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MB46_10735 e3fed882dc5db3254c6854d5e2a5327c 344 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 203 213 - T 14-10-2018 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MB46_10735 e3fed882dc5db3254c6854d5e2a5327c 344 Gene3D G3DSA:3.40.50.1860 119 230 3.9E-87 T 14-10-2018 MB46_10735 e3fed882dc5db3254c6854d5e2a5327c 344 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 90 98 - T 14-10-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MB46_10735 e3fed882dc5db3254c6854d5e2a5327c 344 TIGRFAM TIGR00067 glut_race: glutamate racemase 26 273 5.0E-63 T 14-10-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MB46_10735 e3fed882dc5db3254c6854d5e2a5327c 344 SUPERFAMILY SSF53681 25 131 1.24E-30 T 14-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MB46_10735 e3fed882dc5db3254c6854d5e2a5327c 344 Gene3D G3DSA:3.40.50.1860 25 277 3.9E-87 T 14-10-2018 MB46_09605 16bf640b4228ac83ca18c4c39ce6638e 580 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 116 542 97.41 T 14-10-2018 IPR037509 Phosphomethylpyrimidine synthase GO:0009228|GO:0016830 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 MB46_09605 16bf640b4228ac83ca18c4c39ce6638e 580 Gene3D G3DSA:3.20.20.540 160 473 8.4E-152 T 14-10-2018 IPR038521 ThiC/Bza superfamily KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 MB46_09605 16bf640b4228ac83ca18c4c39ce6638e 580 Pfam PF01964 Radical SAM ThiC family 117 537 7.1E-200 T 14-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 MB46_09605 16bf640b4228ac83ca18c4c39ce6638e 580 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 116 540 1.8E-211 T 14-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 MB46_09605 16bf640b4228ac83ca18c4c39ce6638e 580 Pfam PF13667 ThiC-associated domain 11 73 7.3E-9 T 14-10-2018 IPR025747 ThiC-associated domain KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 MB46_09685 80e22b2431f67234706f13201b41dda3 323 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 76 304 1.3E-36 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MB46_09685 80e22b2431f67234706f13201b41dda3 323 SMART SM00062 75 307 1.7E-18 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MB46_09685 80e22b2431f67234706f13201b41dda3 323 Gene3D G3DSA:3.40.190.10 162 266 4.3E-39 T 14-10-2018 MB46_09685 80e22b2431f67234706f13201b41dda3 323 Gene3D G3DSA:3.40.190.10 73 296 4.3E-39 T 14-10-2018 MB46_09685 80e22b2431f67234706f13201b41dda3 323 SUPERFAMILY SSF53850 65 305 3.72E-43 T 14-10-2018 MB46_07900 d2dc0cb5cf153a45d3355f3049ed5300 223 SUPERFAMILY SSF51735 3 133 7.56E-27 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_07900 d2dc0cb5cf153a45d3355f3049ed5300 223 Pfam PF02254 TrkA-N domain 4 117 3.2E-24 T 14-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 MB46_07900 d2dc0cb5cf153a45d3355f3049ed5300 223 Gene3D G3DSA:3.40.50.720 1 137 9.1E-31 T 14-10-2018 MB46_09855 b4d4b331b28f36c96bee3b058c416f27 247 SUPERFAMILY SSF51735 9 246 2.8E-70 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_09855 b4d4b331b28f36c96bee3b058c416f27 247 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 246 1.8E-53 T 14-10-2018 MB46_09855 b4d4b331b28f36c96bee3b058c416f27 247 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 9 187 3.0E-4 T 14-10-2018 MB46_09855 b4d4b331b28f36c96bee3b058c416f27 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 6.6E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_09855 b4d4b331b28f36c96bee3b058c416f27 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 6.6E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_09855 b4d4b331b28f36c96bee3b058c416f27 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 6.6E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_09855 b4d4b331b28f36c96bee3b058c416f27 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 6.6E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_09855 b4d4b331b28f36c96bee3b058c416f27 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 6.6E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_09855 b4d4b331b28f36c96bee3b058c416f27 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 6.6E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_09855 b4d4b331b28f36c96bee3b058c416f27 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 1.4E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_09855 b4d4b331b28f36c96bee3b058c416f27 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 1.4E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_09855 b4d4b331b28f36c96bee3b058c416f27 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 1.4E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_09855 b4d4b331b28f36c96bee3b058c416f27 247 Gene3D G3DSA:3.40.50.720 2 246 9.7E-71 T 14-10-2018 MB46_09280 24d469a699c87a6f1fa26bec0eb604a5 153 Pfam PF12823 Domain of unknown function (DUF3817) 5 91 1.7E-22 T 14-10-2018 IPR023845 Domain of unknown function DUF3817, transmembrane MB46_09280 24d469a699c87a6f1fa26bec0eb604a5 153 TIGRFAM TIGR03954 integ_memb_HG: integral membrane protein 7 90 1.1E-20 T 14-10-2018 IPR023845 Domain of unknown function DUF3817, transmembrane MB46_06345 47c030426bf986516d3aa742ee7255c9 207 Gene3D G3DSA:3.40.430.10 2 195 2.6E-32 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 MB46_06345 47c030426bf986516d3aa742ee7255c9 207 SUPERFAMILY SSF53597 27 194 4.97E-22 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 MB46_06345 47c030426bf986516d3aa742ee7255c9 207 Pfam PF01872 RibD C-terminal domain 5 182 1.5E-15 T 14-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 MB46_05940 7ba445472698c35e1c136316c80b9a8f 484 SUPERFAMILY SSF51905 1 379 3.18E-38 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_05940 7ba445472698c35e1c136316c80b9a8f 484 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 190 208 5.4E-24 T 14-10-2018 MB46_05940 7ba445472698c35e1c136316c80b9a8f 484 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 136 154 5.4E-24 T 14-10-2018 MB46_05940 7ba445472698c35e1c136316c80b9a8f 484 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 5.4E-24 T 14-10-2018 MB46_05940 7ba445472698c35e1c136316c80b9a8f 484 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 276 292 5.4E-24 T 14-10-2018 MB46_05940 7ba445472698c35e1c136316c80b9a8f 484 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 305 327 5.4E-24 T 14-10-2018 MB46_05940 7ba445472698c35e1c136316c80b9a8f 484 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 361 470 1.2E-23 T 14-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 MB46_05940 7ba445472698c35e1c136316c80b9a8f 484 Gene3D G3DSA:3.30.390.30 360 481 2.2E-31 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 MB46_05940 7ba445472698c35e1c136316c80b9a8f 484 Gene3D G3DSA:3.50.50.60 4 346 2.0E-88 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_05940 7ba445472698c35e1c136316c80b9a8f 484 SUPERFAMILY SSF55424 358 472 8.42E-29 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 MB46_05940 7ba445472698c35e1c136316c80b9a8f 484 Gene3D G3DSA:3.50.50.60 154 290 2.0E-88 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_05940 7ba445472698c35e1c136316c80b9a8f 484 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 36 46 - T 14-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 MB46_05940 7ba445472698c35e1c136316c80b9a8f 484 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 422 437 2.6E-40 T 14-10-2018 MB46_05940 7ba445472698c35e1c136316c80b9a8f 484 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 190 215 2.6E-40 T 14-10-2018 MB46_05940 7ba445472698c35e1c136316c80b9a8f 484 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 155 164 2.6E-40 T 14-10-2018 MB46_05940 7ba445472698c35e1c136316c80b9a8f 484 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 2.6E-40 T 14-10-2018 MB46_05940 7ba445472698c35e1c136316c80b9a8f 484 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 320 327 2.6E-40 T 14-10-2018 MB46_05940 7ba445472698c35e1c136316c80b9a8f 484 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 277 291 2.6E-40 T 14-10-2018 MB46_05940 7ba445472698c35e1c136316c80b9a8f 484 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 357 378 2.6E-40 T 14-10-2018 MB46_05940 7ba445472698c35e1c136316c80b9a8f 484 PIRSF PIRSF000350 1 463 3.2E-77 T 14-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 MB46_05940 7ba445472698c35e1c136316c80b9a8f 484 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 340 1.1E-44 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MB46_07945 f3fd3a146ab2d602f74884e8ed7f94eb 400 SUPERFAMILY SSF53649 43 385 2.62E-55 T 14-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 MB46_07945 f3fd3a146ab2d602f74884e8ed7f94eb 400 Gene3D G3DSA:3.40.720.10 35 389 4.6E-49 T 14-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 MB46_07945 f3fd3a146ab2d602f74884e8ed7f94eb 400 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 48 373 4.6E-32 T 14-10-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 MB46_04030 c1ed585d863bf932a85f086c428fd41a 63 Pfam PF17227 Family of unknown function (DUF5302) 14 63 1.9E-17 T 14-10-2018 IPR035172 Protein of unknown function DUF5302 MB46_03730 de14055d81e04220ec78db1170d585cc 328 SUPERFAMILY SSF56112 50 293 1.9E-18 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily MB46_03730 de14055d81e04220ec78db1170d585cc 328 Pfam PF04655 Aminoglycoside/hydroxyurea antibiotic resistance kinase 48 292 1.7E-27 T 14-10-2018 IPR006748 Aminoglycoside/hydroxyurea antibiotic resistance kinase GO:0006468|GO:0016773|GO:0019748 MB46_06770 0ea7aea24eb1a95281912f3dc0edfb07 343 Gene3D G3DSA:3.40.50.720 150 285 3.3E-99 T 14-10-2018 MB46_06770 0ea7aea24eb1a95281912f3dc0edfb07 343 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 15 128 5.7E-28 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MB46_06770 0ea7aea24eb1a95281912f3dc0edfb07 343 Pfam PF00107 Zinc-binding dehydrogenase 173 299 1.3E-26 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 MB46_06770 0ea7aea24eb1a95281912f3dc0edfb07 343 Gene3D G3DSA:3.90.180.10 15 326 3.3E-99 T 14-10-2018 MB46_06770 0ea7aea24eb1a95281912f3dc0edfb07 343 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 49 63 - T 14-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 MB46_06770 0ea7aea24eb1a95281912f3dc0edfb07 343 SUPERFAMILY SSF51735 134 304 3.25E-42 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_06770 0ea7aea24eb1a95281912f3dc0edfb07 343 SUPERFAMILY SSF50129 4 151 5.03E-47 T 14-10-2018 IPR011032 GroES-like superfamily MB46_06770 0ea7aea24eb1a95281912f3dc0edfb07 343 SMART SM00829 20 339 2.9E-4 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MB46_08790 5e088f3865b9f670681f8e2caec6294d 154 SUPERFAMILY SSF55811 19 150 1.29E-29 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 MB46_08790 5e088f3865b9f670681f8e2caec6294d 154 Gene3D G3DSA:3.90.79.10 23 153 9.4E-24 T 14-10-2018 MB46_08790 5e088f3865b9f670681f8e2caec6294d 154 ProSitePatterns PS00893 Nudix box signature. 57 78 - T 14-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 MB46_08790 5e088f3865b9f670681f8e2caec6294d 154 Pfam PF00293 NUDIX domain 25 135 1.5E-18 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MB46_03610 ba497cc3b41f088b350cf7f5ed6056b9 217 Pfam PF01144 Coenzyme A transferase 7 201 1.2E-46 T 14-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 MB46_03610 ba497cc3b41f088b350cf7f5ed6056b9 217 ProSitePatterns PS01274 Coenzyme A transferases signature 2. 44 52 - T 14-10-2018 IPR004164 Coenzyme A transferase active site GO:0008410 Reactome: R-HSA-77108 MB46_03610 ba497cc3b41f088b350cf7f5ed6056b9 217 SMART SM00882 6 202 7.0E-75 T 14-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 MB46_03610 ba497cc3b41f088b350cf7f5ed6056b9 217 TIGRFAM TIGR02428 pcaJ_scoB_fam: 3-oxoacid CoA-transferase, B subunit 4 208 5.6E-101 T 14-10-2018 IPR012791 3-oxoacid CoA-transferase, subunit B GO:0008410 Reactome: R-HSA-77108 MB46_03610 ba497cc3b41f088b350cf7f5ed6056b9 217 SUPERFAMILY SSF100950 5 209 5.07E-73 T 14-10-2018 IPR037171 NagB/RpiA transferase-like MB46_03610 ba497cc3b41f088b350cf7f5ed6056b9 217 Gene3D G3DSA:3.40.1080.10 1 212 1.3E-102 T 14-10-2018 MB46_08160 511c56bf9f971ece5fdcaeb6a6c10782 264 Pfam PF00480 ROK family 12 172 2.6E-24 T 14-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 MB46_08160 511c56bf9f971ece5fdcaeb6a6c10782 264 Gene3D G3DSA:3.30.420.40 1 119 8.0E-30 T 14-10-2018 MB46_08160 511c56bf9f971ece5fdcaeb6a6c10782 264 Gene3D G3DSA:3.30.420.40 120 263 2.2E-41 T 14-10-2018 MB46_08160 511c56bf9f971ece5fdcaeb6a6c10782 264 SUPERFAMILY SSF53067 11 260 1.37E-39 T 14-10-2018 MB46_12815 d405e3693b3e95fb508bbc1d3b95293f 506 Pfam PF02610 L-arabinose isomerase 11 363 1.4E-171 T 14-10-2018 IPR003762 L-arabinose isomerase GO:0008733 KEGG: 00040+5.3.1.4 MB46_12815 d405e3693b3e95fb508bbc1d3b95293f 506 Gene3D G3DSA:3.40.50.10940 6 180 4.5E-78 T 14-10-2018 IPR038583 L-arabinose isomerase, N-terminal domain superfamily KEGG: 00040+5.3.1.4 MB46_12815 d405e3693b3e95fb508bbc1d3b95293f 506 SUPERFAMILY SSF50443 334 502 1.83E-63 T 14-10-2018 IPR004216 L-fucose/L-arabinose isomerase, C-terminal MB46_12815 d405e3693b3e95fb508bbc1d3b95293f 506 Pfam PF11762 L-arabinose isomerase C-terminal domain 367 480 1.5E-45 T 14-10-2018 IPR024664 L-arabinose isomerase, C-terminal KEGG: 00040+5.3.1.4 MB46_12815 d405e3693b3e95fb508bbc1d3b95293f 506 PIRSF PIRSF001478 6 504 2.3E-229 T 14-10-2018 IPR003762 L-arabinose isomerase GO:0008733 KEGG: 00040+5.3.1.4 MB46_12815 d405e3693b3e95fb508bbc1d3b95293f 506 ProDom PD018364 ISOMERASE L-ARABINOSE ARABINOSE METABOLISM CARBOHYDRATE CATABOLISM ARAA 8 309 3.0E-118 T 14-10-2018 IPR003762 L-arabinose isomerase GO:0008733 KEGG: 00040+5.3.1.4 MB46_12815 d405e3693b3e95fb508bbc1d3b95293f 506 SUPERFAMILY SSF53743 11 332 2.22E-118 T 14-10-2018 IPR009015 L-fucose isomerase, N-terminal/central domain superfamily GO:0005737|GO:0005996|GO:0016861 MB46_12815 d405e3693b3e95fb508bbc1d3b95293f 506 Hamap MF_00519 L-arabinose isomerase [araA]. 6 481 62.579 T 14-10-2018 IPR003762 L-arabinose isomerase GO:0008733 KEGG: 00040+5.3.1.4 MB46_11065 987f054b81d3f701ca3257065dd57587 153 SUPERFAMILY SSF46785 6 151 2.81E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_11065 987f054b81d3f701ca3257065dd57587 153 Gene3D G3DSA:1.10.10.10 8 153 4.2E-26 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_11065 987f054b81d3f701ca3257065dd57587 153 SMART SM00347 28 139 3.8E-6 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MB46_11065 987f054b81d3f701ca3257065dd57587 153 Pfam PF09339 IclR helix-turn-helix domain 42 84 5.0E-8 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 MB46_02460 9ba990b94710994298d5e857812acc4e 187 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 5 93 6.0E-24 T 14-10-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 MB46_02460 9ba990b94710994298d5e857812acc4e 187 Gene3D G3DSA:2.170.120.20 96 185 1.6E-11 T 14-10-2018 IPR037121 Ribosomal protein L25, C-terminal MB46_02460 9ba990b94710994298d5e857812acc4e 187 TIGRFAM TIGR00731 bL25_bact_ctc: ribosomal protein bL25, Ctc-form 6 172 8.7E-40 T 14-10-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 MB46_02460 9ba990b94710994298d5e857812acc4e 187 Pfam PF14693 Ribosomal protein TL5, C-terminal domain 98 176 1.4E-13 T 14-10-2018 IPR020057 Ribosomal protein L25, beta domain MB46_02460 9ba990b94710994298d5e857812acc4e 187 Gene3D G3DSA:2.40.240.10 2 93 3.7E-24 T 14-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 MB46_02460 9ba990b94710994298d5e857812acc4e 187 Pfam PF01386 Ribosomal L25p family 6 90 3.0E-23 T 14-10-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 MB46_02460 9ba990b94710994298d5e857812acc4e 187 SUPERFAMILY SSF50715 4 182 4.53E-41 T 14-10-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 MB46_02460 9ba990b94710994298d5e857812acc4e 187 Hamap MF_01334 50S ribosomal protein L25 [rplY]. 4 175 24.232 T 14-10-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 MB46_17600 b1538b576fc28a4213364aba860191c4 487 Gene3D G3DSA:3.30.420.40 238 484 4.5E-90 T 14-10-2018 MB46_17600 b1538b576fc28a4213364aba860191c4 487 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 6 243 6.1E-28 T 14-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 MB46_17600 b1538b576fc28a4213364aba860191c4 487 SUPERFAMILY SSF53067 252 462 1.19E-32 T 14-10-2018 MB46_17600 b1538b576fc28a4213364aba860191c4 487 SUPERFAMILY SSF53067 5 244 4.75E-43 T 14-10-2018 MB46_17600 b1538b576fc28a4213364aba860191c4 487 PIRSF PIRSF000538 2 479 5.7E-42 T 14-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 MB46_17600 b1538b576fc28a4213364aba860191c4 487 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 254 455 2.0E-33 T 14-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 MB46_17600 b1538b576fc28a4213364aba860191c4 487 Gene3D G3DSA:3.30.420.40 3 237 7.5E-71 T 14-10-2018 MB46_06075 2b39ea177e53385354ec1664deaa2f43 269 SMART SM00382 35 224 5.1E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_06075 2b39ea177e53385354ec1664deaa2f43 269 Pfam PF00005 ABC transporter 28 174 5.6E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_06075 2b39ea177e53385354ec1664deaa2f43 269 SUPERFAMILY SSF52540 11 237 1.52E-57 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_06075 2b39ea177e53385354ec1664deaa2f43 269 Gene3D G3DSA:3.40.50.300 3 262 6.6E-65 T 14-10-2018 MB46_06075 2b39ea177e53385354ec1664deaa2f43 269 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_06830 19abaeb66de5b799938e0520755aadfa 277 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 71 274 2.8E-60 T 14-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 MB46_06830 19abaeb66de5b799938e0520755aadfa 277 Gene3D G3DSA:3.90.850.10 66 277 2.1E-73 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 MB46_06830 19abaeb66de5b799938e0520755aadfa 277 SUPERFAMILY SSF56529 60 275 1.57E-73 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 MB46_14040 63210c747987557c828dcf6c3079cbee 418 Gene3D G3DSA:3.30.565.10 266 395 6.7E-21 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MB46_14040 63210c747987557c828dcf6c3079cbee 418 Pfam PF07730 Histidine kinase 189 254 3.2E-17 T 14-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 MB46_14040 63210c747987557c828dcf6c3079cbee 418 SUPERFAMILY SSF55874 298 395 7.26E-10 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MB46_13240 0c71f959d121fa2b12010ca93da38331 322 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 95 254 2.9E-13 T 14-10-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0016301 Reactome: R-HSA-73614 MB46_13240 0c71f959d121fa2b12010ca93da38331 322 Gene3D G3DSA:3.40.50.300 8 322 4.1E-89 T 14-10-2018 MB46_13240 0c71f959d121fa2b12010ca93da38331 322 PIRSF PIRSF000545 6 322 4.7E-139 T 14-10-2018 IPR004566 Pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 MB46_13240 0c71f959d121fa2b12010ca93da38331 322 TIGRFAM TIGR00554 panK_bact: pantothenate kinase 16 321 7.5E-127 T 14-10-2018 IPR004566 Pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 MB46_13240 0c71f959d121fa2b12010ca93da38331 322 Hamap MF_00215 Pantothenate kinase [coaA]. 1 322 167.76 T 14-10-2018 IPR004566 Pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 MB46_13240 0c71f959d121fa2b12010ca93da38331 322 SUPERFAMILY SSF52540 15 321 5.27E-69 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_04310 aa64ae41306f5cc65a74b32d72a9900d 544 SUPERFAMILY SSF51338 9 523 1.2E-19 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 MB46_04310 aa64ae41306f5cc65a74b32d72a9900d 544 Gene3D G3DSA:3.20.20.140 63 303 2.1E-77 T 14-10-2018 MB46_04310 aa64ae41306f5cc65a74b32d72a9900d 544 Gene3D G3DSA:3.20.20.140 304 468 5.8E-23 T 14-10-2018 MB46_04310 aa64ae41306f5cc65a74b32d72a9900d 544 Pfam PF07969 Amidohydrolase family 53 516 1.1E-41 T 14-10-2018 IPR013108 Amidohydrolase 3 MB46_04310 aa64ae41306f5cc65a74b32d72a9900d 544 SUPERFAMILY SSF51556 64 474 6.13E-74 T 14-10-2018 IPR032466 Metal-dependent hydrolase MB46_11910 ecee4bc00ea0d5f2a61213132a673095 382 Pfam PF01594 AI-2E family transporter 29 339 1.3E-34 T 14-10-2018 IPR002549 Transmembrane protein TqsA-like MB46_19105 a493bb1e42be4fb1eff3f79fc39b474e 595 Gene3D G3DSA:3.90.400.10 123 192 1.4E-202 T 14-10-2018 MB46_19105 a493bb1e42be4fb1eff3f79fc39b474e 595 SUPERFAMILY SSF51011 487 569 6.16E-11 T 14-10-2018 MB46_19105 a493bb1e42be4fb1eff3f79fc39b474e 595 Gene3D G3DSA:2.60.40.1180 481 572 2.1E-21 T 14-10-2018 IPR013780 Glycosyl hydrolase, all-beta MB46_19105 a493bb1e42be4fb1eff3f79fc39b474e 595 SUPERFAMILY SSF51445 22 478 4.83E-123 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily MB46_19105 a493bb1e42be4fb1eff3f79fc39b474e 595 SMART SM00642 33 433 4.6E-101 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MB46_19105 a493bb1e42be4fb1eff3f79fc39b474e 595 Pfam PF00128 Alpha amylase, catalytic domain 48 402 2.2E-73 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MB46_19105 a493bb1e42be4fb1eff3f79fc39b474e 595 Gene3D G3DSA:3.20.20.80 25 476 1.4E-202 T 14-10-2018 MB46_19105 a493bb1e42be4fb1eff3f79fc39b474e 595 TIGRFAM TIGR02456 treS_nterm: trehalose synthase 24 570 6.6E-264 T 14-10-2018 IPR012810 Trehalose synthase/alpha-amylase, N-terminal GO:0003824|GO:0005975 KEGG: 00500+5.4.99.16|MetaCyc: PWY-2622|MetaCyc: PWY-7900 MB46_19105 a493bb1e42be4fb1eff3f79fc39b474e 595 Pfam PF16657 Maltogenic Amylase, C-terminal domain 481 567 7.7E-16 T 14-10-2018 IPR032091 Maltogenic Amylase, C-terminal MB46_10110 2ee11f966c03801c3bc4bfd372b51e50 235 SUPERFAMILY SSF46894 158 232 1.22E-22 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MB46_10110 2ee11f966c03801c3bc4bfd372b51e50 235 SMART SM00421 169 226 7.2E-26 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_10110 2ee11f966c03801c3bc4bfd372b51e50 235 Pfam PF00196 Bacterial regulatory proteins, luxR family 171 226 6.5E-20 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_10110 2ee11f966c03801c3bc4bfd372b51e50 235 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 172 186 2.3E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_10110 2ee11f966c03801c3bc4bfd372b51e50 235 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 186 202 2.3E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_10110 2ee11f966c03801c3bc4bfd372b51e50 235 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 202 214 2.3E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_10110 2ee11f966c03801c3bc4bfd372b51e50 235 Pfam PF00072 Response regulator receiver domain 9 129 3.8E-24 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MB46_10110 2ee11f966c03801c3bc4bfd372b51e50 235 SMART SM00448 7 129 2.6E-30 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MB46_10110 2ee11f966c03801c3bc4bfd372b51e50 235 SUPERFAMILY SSF52172 6 148 1.39E-31 T 14-10-2018 IPR011006 CheY-like superfamily MB46_10110 2ee11f966c03801c3bc4bfd372b51e50 235 Gene3D G3DSA:3.40.50.12740 7 232 2.5E-66 T 14-10-2018 MB46_10110 2ee11f966c03801c3bc4bfd372b51e50 235 ProSitePatterns PS00622 LuxR-type HTH domain signature. 186 213 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_14205 b89e61b9415d4f8fa9b75f96b2f4f217 268 Pfam PF12833 Helix-turn-helix domain 183 261 4.4E-21 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MB46_14205 b89e61b9415d4f8fa9b75f96b2f4f217 268 Gene3D G3DSA:1.10.10.60 162 266 1.2E-22 T 14-10-2018 MB46_14205 b89e61b9415d4f8fa9b75f96b2f4f217 268 SUPERFAMILY SSF46689 213 263 5.82E-7 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MB46_14205 b89e61b9415d4f8fa9b75f96b2f4f217 268 SMART SM00342 176 260 6.3E-17 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MB46_11725 86380d6dec395d00d266731a2394e0c5 499 Gene3D G3DSA:3.40.50.200 153 499 8.7E-79 T 14-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 MB46_11725 86380d6dec395d00d266731a2394e0c5 499 SUPERFAMILY SSF52743 168 498 6.41E-72 T 14-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 MB46_11725 86380d6dec395d00d266731a2394e0c5 499 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 237 247 - T 14-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site MB46_11725 86380d6dec395d00d266731a2394e0c5 499 PRINTS PR00723 Subtilisin serine protease family (S8) signature 186 205 2.6E-18 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related MB46_11725 86380d6dec395d00d266731a2394e0c5 499 PRINTS PR00723 Subtilisin serine protease family (S8) signature 233 246 2.6E-18 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related MB46_11725 86380d6dec395d00d266731a2394e0c5 499 PRINTS PR00723 Subtilisin serine protease family (S8) signature 425 441 2.6E-18 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related MB46_11725 86380d6dec395d00d266731a2394e0c5 499 Pfam PF00082 Subtilase family 188 458 7.5E-45 T 14-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 MB46_11725 86380d6dec395d00d266731a2394e0c5 499 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 426 436 - T 14-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site MB46_11725 86380d6dec395d00d266731a2394e0c5 499 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 191 202 - T 14-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site MB46_00145 49d33ddaf3056870720fd73637c44a6d 558 Gene3D G3DSA:3.90.76.10 78 178 2.1E-160 T 14-10-2018 MB46_00145 49d33ddaf3056870720fd73637c44a6d 558 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 91 456 3.3E-79 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain MB46_00145 49d33ddaf3056870720fd73637c44a6d 558 PIRSF PIRSF002741 7 521 1.1E-76 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 MB46_00145 49d33ddaf3056870720fd73637c44a6d 558 SUPERFAMILY SSF53850 59 536 6.7E-104 T 14-10-2018 MB46_00145 49d33ddaf3056870720fd73637c44a6d 558 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 95 117 - T 14-10-2018 IPR023765 Solute-binding protein family 5, conserved site MB46_00145 49d33ddaf3056870720fd73637c44a6d 558 Gene3D G3DSA:3.40.190.10 59 539 2.1E-160 T 14-10-2018 MB46_00145 49d33ddaf3056870720fd73637c44a6d 558 Gene3D G3DSA:3.10.105.10 279 519 2.1E-160 T 14-10-2018 MB46_00465 e1399caad17f72de7cb935996144a1bc 173 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 49 165 6.9E-22 T 14-10-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 MB46_00465 e1399caad17f72de7cb935996144a1bc 173 SUPERFAMILY SSF54637 29 165 1.59E-36 T 14-10-2018 IPR029069 HotDog domain superfamily MB46_00465 e1399caad17f72de7cb935996144a1bc 173 Pfam PF03061 Thioesterase superfamily 80 157 6.1E-15 T 14-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 MB46_00465 e1399caad17f72de7cb935996144a1bc 173 Gene3D G3DSA:3.10.129.10 31 169 1.3E-38 T 14-10-2018 MB46_17850 e8cebe371bb5317c1d3084a56fb7667c 359 SUPERFAMILY SSF55347 128 243 1.57E-19 T 14-10-2018 MB46_17850 e8cebe371bb5317c1d3084a56fb7667c 359 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 127 183 5.0E-6 T 14-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 MB46_17850 e8cebe371bb5317c1d3084a56fb7667c 359 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 2 110 4.5E-10 T 14-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 MB46_17850 e8cebe371bb5317c1d3084a56fb7667c 359 SUPERFAMILY SSF51735 1 140 1.06E-26 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_17850 e8cebe371bb5317c1d3084a56fb7667c 359 Gene3D G3DSA:3.40.50.720 1 127 2.0E-22 T 14-10-2018 MB46_17850 e8cebe371bb5317c1d3084a56fb7667c 359 Gene3D G3DSA:3.30.360.10 128 318 1.7E-31 T 14-10-2018 MB46_07860 3eb4c4f9b88c8355e30cfc389ebd140d 325 PRINTS PR00069 Aldo-keto reductase signature 144 161 5.1E-5 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MB46_07860 3eb4c4f9b88c8355e30cfc389ebd140d 325 PRINTS PR00069 Aldo-keto reductase signature 44 68 5.1E-5 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MB46_07860 3eb4c4f9b88c8355e30cfc389ebd140d 325 Gene3D G3DSA:3.20.20.100 1 323 8.4E-108 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily MB46_07860 3eb4c4f9b88c8355e30cfc389ebd140d 325 SUPERFAMILY SSF51430 2 320 6.29E-96 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily MB46_07860 3eb4c4f9b88c8355e30cfc389ebd140d 325 Pfam PF00248 Aldo/keto reductase family 17 315 9.4E-69 T 14-10-2018 IPR023210 NADP-dependent oxidoreductase domain MB46_15575 a241cbf75fb596785ab4616ac8fde625 355 Gene3D G3DSA:3.40.50.10330 44 180 1.5E-25 T 14-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 MB46_15575 a241cbf75fb596785ab4616ac8fde625 355 SMART SM00046 50 175 2.5E-6 T 14-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 MB46_15575 a241cbf75fb596785ab4616ac8fde625 355 Pfam PF00781 Diacylglycerol kinase catalytic domain 51 170 6.3E-20 T 14-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 MB46_15575 a241cbf75fb596785ab4616ac8fde625 355 SUPERFAMILY SSF111331 50 349 5.23E-61 T 14-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily MB46_15575 a241cbf75fb596785ab4616ac8fde625 355 Gene3D G3DSA:2.60.200.40 182 341 5.8E-38 T 14-10-2018 MB46_01780 ddb3fef5f2002b5247090e9344d8b7c6 523 Pfam PF07905 Purine catabolism regulatory protein-like family 31 132 3.0E-18 T 14-10-2018 IPR012914 Purine catabolism PurC-like domain MB46_01780 ddb3fef5f2002b5247090e9344d8b7c6 523 Gene3D G3DSA:1.10.10.2840 366 520 1.4E-15 T 14-10-2018 MB46_01780 ddb3fef5f2002b5247090e9344d8b7c6 523 Pfam PF13556 PucR C-terminal helix-turn-helix domain 460 517 2.6E-17 T 14-10-2018 IPR025736 PucR C-terminal helix-turn-helix domain MB46_10980 e576a6371483bd4a6e78114fae05fc85 280 PRINTS PR00111 Alpha/beta hydrolase fold signature 51 66 2.1E-9 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MB46_10980 e576a6371483bd4a6e78114fae05fc85 280 PRINTS PR00111 Alpha/beta hydrolase fold signature 223 237 2.1E-9 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MB46_10980 e576a6371483bd4a6e78114fae05fc85 280 PRINTS PR00111 Alpha/beta hydrolase fold signature 95 108 2.1E-9 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MB46_10980 e576a6371483bd4a6e78114fae05fc85 280 Gene3D G3DSA:3.40.50.1820 2 278 8.5E-90 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_10980 e576a6371483bd4a6e78114fae05fc85 280 Pfam PF00561 alpha/beta hydrolase fold 26 266 2.3E-31 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MB46_10980 e576a6371483bd4a6e78114fae05fc85 280 SUPERFAMILY SSF53474 4 279 1.76E-57 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_10980 e576a6371483bd4a6e78114fae05fc85 280 PRINTS PR00412 Epoxide hydrolase signature 31 49 8.4E-6 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MB46_10980 e576a6371483bd4a6e78114fae05fc85 280 PRINTS PR00412 Epoxide hydrolase signature 255 277 8.4E-6 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MB46_10980 e576a6371483bd4a6e78114fae05fc85 280 PRINTS PR00412 Epoxide hydrolase signature 51 66 8.4E-6 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MB46_15260 6274ff4acf8d69e485ec8b293be286b6 315 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 254 267 - T 14-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 MB46_15260 6274ff4acf8d69e485ec8b293be286b6 315 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 2 312 3.7E-87 T 14-10-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 MB46_15260 6274ff4acf8d69e485ec8b293be286b6 315 Gene3D G3DSA:3.40.1190.20 1 314 1.4E-93 T 14-10-2018 IPR029056 Ribokinase-like MB46_15260 6274ff4acf8d69e485ec8b293be286b6 315 PIRSF PIRSF000535 1 314 1.9E-62 T 14-10-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 MB46_15260 6274ff4acf8d69e485ec8b293be286b6 315 Pfam PF00294 pfkB family carbohydrate kinase 9 298 1.0E-32 T 14-10-2018 IPR011611 Carbohydrate kinase PfkB MB46_15260 6274ff4acf8d69e485ec8b293be286b6 315 SUPERFAMILY SSF53613 1 299 1.5E-52 T 14-10-2018 IPR029056 Ribokinase-like MB46_15025 214f469711aa74327d0a8fd887c87e5e 392 SUPERFAMILY SSF54631 239 355 3.79E-19 T 14-10-2018 MB46_15025 214f469711aa74327d0a8fd887c87e5e 392 SUPERFAMILY SSF52540 8 235 1.93E-74 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_15025 214f469711aa74327d0a8fd887c87e5e 392 Gene3D G3DSA:3.10.580.10 246 357 4.7E-13 T 14-10-2018 MB46_15025 214f469711aa74327d0a8fd887c87e5e 392 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 6 356 9.5E-129 T 14-10-2018 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 MB46_15025 214f469711aa74327d0a8fd887c87e5e 392 Gene3D G3DSA:3.40.50.300 4 245 3.5E-79 T 14-10-2018 MB46_15025 214f469711aa74327d0a8fd887c87e5e 392 SMART SM00382 18 215 8.9E-17 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_15025 214f469711aa74327d0a8fd887c87e5e 392 Pfam PF00005 ABC transporter 11 157 1.6E-31 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_15025 214f469711aa74327d0a8fd887c87e5e 392 Pfam PF00571 CBS domain 242 292 1.8E-4 T 14-10-2018 IPR000644 CBS domain MB46_15025 214f469711aa74327d0a8fd887c87e5e 392 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_09760 c7a2de0b0b82b97580d49a6f5ad87666 265 Gene3D G3DSA:3.30.160.20 163 236 1.2E-17 T 14-10-2018 MB46_09760 c7a2de0b0b82b97580d49a6f5ad87666 265 SMART SM00358 168 234 1.8E-19 T 14-10-2018 IPR014720 Double-stranded RNA-binding domain MB46_09760 c7a2de0b0b82b97580d49a6f5ad87666 265 ProSitePatterns PS00517 Ribonuclease III family signature. 50 58 - T 14-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 MB46_09760 c7a2de0b0b82b97580d49a6f5ad87666 265 SUPERFAMILY SSF54768 122 233 6.29E-22 T 14-10-2018 MB46_09760 c7a2de0b0b82b97580d49a6f5ad87666 265 Hamap MF_00104 Ribonuclease 3 [rnc]. 17 230 27.342 T 14-10-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 MB46_09760 c7a2de0b0b82b97580d49a6f5ad87666 265 SMART SM00535 28 161 3.4E-50 T 14-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 MB46_09760 c7a2de0b0b82b97580d49a6f5ad87666 265 Pfam PF00035 Double-stranded RNA binding motif 169 231 5.3E-11 T 14-10-2018 IPR014720 Double-stranded RNA-binding domain MB46_09760 c7a2de0b0b82b97580d49a6f5ad87666 265 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 20 231 2.6E-64 T 14-10-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 MB46_09760 c7a2de0b0b82b97580d49a6f5ad87666 265 SUPERFAMILY SSF69065 12 169 2.09E-43 T 14-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 MB46_09760 c7a2de0b0b82b97580d49a6f5ad87666 265 Gene3D G3DSA:1.10.1520.10 11 160 1.4E-41 T 14-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 MB46_09760 c7a2de0b0b82b97580d49a6f5ad87666 265 Pfam PF14622 Ribonuclease-III-like 29 150 5.0E-35 T 14-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 MB46_01610 343d9133661311d6bd8924554678aff0 513 Gene3D G3DSA:1.10.287.1060 1 93 5.3E-9 T 14-10-2018 MB46_01610 343d9133661311d6bd8924554678aff0 513 SUPERFAMILY SSF140453 7 85 7.32E-5 T 14-10-2018 IPR036689 ESAT-6-like superfamily MB46_03675 ce52a991879e3fc0ab116cf5240f3f59 97 SUPERFAMILY SSF54909 1 87 1.9E-17 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel MB46_03675 ce52a991879e3fc0ab116cf5240f3f59 97 Pfam PF03795 YCII-related domain 6 85 8.0E-9 T 14-10-2018 IPR005545 YCII-related MB46_03675 ce52a991879e3fc0ab116cf5240f3f59 97 Gene3D G3DSA:3.30.70.1060 2 89 8.3E-10 T 14-10-2018 MB46_05055 5394a3156753c21bdd0a54fc1a9b8a39 207 PRINTS PR01703 Manganese superoxide dismutase signature 67 80 7.0E-21 T 14-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MB46_05055 5394a3156753c21bdd0a54fc1a9b8a39 207 PRINTS PR01703 Manganese superoxide dismutase signature 158 170 7.0E-21 T 14-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MB46_05055 5394a3156753c21bdd0a54fc1a9b8a39 207 PRINTS PR01703 Manganese superoxide dismutase signature 7 18 7.0E-21 T 14-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MB46_05055 5394a3156753c21bdd0a54fc1a9b8a39 207 PRINTS PR01703 Manganese superoxide dismutase signature 120 128 7.0E-21 T 14-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MB46_05055 5394a3156753c21bdd0a54fc1a9b8a39 207 PRINTS PR01703 Manganese superoxide dismutase signature 28 41 7.0E-21 T 14-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MB46_05055 5394a3156753c21bdd0a54fc1a9b8a39 207 Gene3D G3DSA:1.10.287.990 21 84 4.1E-26 T 14-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MB46_05055 5394a3156753c21bdd0a54fc1a9b8a39 207 PIRSF PIRSF000349 1 203 2.0E-76 T 14-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MB46_05055 5394a3156753c21bdd0a54fc1a9b8a39 207 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 160 167 - T 14-10-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MB46_05055 5394a3156753c21bdd0a54fc1a9b8a39 207 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 91 193 9.8E-34 T 14-10-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MB46_05055 5394a3156753c21bdd0a54fc1a9b8a39 207 SUPERFAMILY SSF46609 2 88 3.67E-31 T 14-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MB46_05055 5394a3156753c21bdd0a54fc1a9b8a39 207 SUPERFAMILY SSF54719 84 198 2.88E-42 T 14-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MB46_05055 5394a3156753c21bdd0a54fc1a9b8a39 207 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 3 84 2.2E-30 T 14-10-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MB46_05055 5394a3156753c21bdd0a54fc1a9b8a39 207 Gene3D G3DSA:2.40.500.20 85 207 1.9E-44 T 14-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MB46_09000 51380a45d0a1fceefa2d9e5c4600b716 1086 Gene3D G3DSA:3.40.50.620 30 684 1.8E-222 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MB46_09000 51380a45d0a1fceefa2d9e5c4600b716 1086 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 67 78 - T 14-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 MB46_09000 51380a45d0a1fceefa2d9e5c4600b716 1086 SUPERFAMILY SSF52374 20 691 5.14E-128 T 14-10-2018 MB46_09000 51380a45d0a1fceefa2d9e5c4600b716 1086 Pfam PF08264 Anticodon-binding domain of tRNA 748 885 4.0E-17 T 14-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 MB46_09000 51380a45d0a1fceefa2d9e5c4600b716 1086 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 20 895 1.5E-243 T 14-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 MB46_09000 51380a45d0a1fceefa2d9e5c4600b716 1086 Gene3D G3DSA:1.10.730.10 700 880 2.9E-37 T 14-10-2018 MB46_09000 51380a45d0a1fceefa2d9e5c4600b716 1086 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 442 457 8.4E-31 T 14-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 MB46_09000 51380a45d0a1fceefa2d9e5c4600b716 1086 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 577 590 8.4E-31 T 14-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 MB46_09000 51380a45d0a1fceefa2d9e5c4600b716 1086 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 60 71 8.4E-31 T 14-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 MB46_09000 51380a45d0a1fceefa2d9e5c4600b716 1086 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 251 274 8.4E-31 T 14-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 MB46_09000 51380a45d0a1fceefa2d9e5c4600b716 1086 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 617 626 8.4E-31 T 14-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 MB46_09000 51380a45d0a1fceefa2d9e5c4600b716 1086 SUPERFAMILY SSF47323 713 951 9.16E-36 T 14-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 MB46_09000 51380a45d0a1fceefa2d9e5c4600b716 1086 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 34 692 2.5E-171 T 14-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 MB46_09000 51380a45d0a1fceefa2d9e5c4600b716 1086 Gene3D G3DSA:3.90.740.10 216 448 1.8E-222 T 14-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 MB46_09000 51380a45d0a1fceefa2d9e5c4600b716 1086 SUPERFAMILY SSF50677 222 444 4.58E-37 T 14-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 MB46_09000 51380a45d0a1fceefa2d9e5c4600b716 1086 Hamap MF_02003 Isoleucine--tRNA ligase [ileS]. 18 1082 13.595 T 14-10-2018 IPR023586 Isoleucine-tRNA ligase, type 2 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 MB46_00380 218e6a24cc4141aefdbc6fa40d59a48a 253 Gene3D G3DSA:2.60.120.10 15 131 8.5E-9 T 14-10-2018 IPR014710 RmlC-like jelly roll fold MB46_00380 218e6a24cc4141aefdbc6fa40d59a48a 253 Pfam PF02311 AraC-like ligand binding domain 30 112 3.3E-12 T 14-10-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 MB46_00380 218e6a24cc4141aefdbc6fa40d59a48a 253 SMART SM00342 168 250 2.0E-20 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MB46_00380 218e6a24cc4141aefdbc6fa40d59a48a 253 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 205 246 - T 14-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 MB46_00380 218e6a24cc4141aefdbc6fa40d59a48a 253 Gene3D G3DSA:1.10.10.60 152 253 1.1E-19 T 14-10-2018 MB46_00380 218e6a24cc4141aefdbc6fa40d59a48a 253 SUPERFAMILY SSF46689 204 249 2.44E-7 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MB46_00380 218e6a24cc4141aefdbc6fa40d59a48a 253 SUPERFAMILY SSF51182 19 182 5.51E-13 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily MB46_00380 218e6a24cc4141aefdbc6fa40d59a48a 253 Pfam PF12833 Helix-turn-helix domain 174 252 4.4E-18 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MB46_16100 2b5b6fd6a87045ee91d102fd64d7e26e 484 SMART SM00382 175 305 6.8E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_16100 2b5b6fd6a87045ee91d102fd64d7e26e 484 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 13 477 5.5E-161 T 14-10-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 MB46_16100 2b5b6fd6a87045ee91d102fd64d7e26e 484 ProSitePatterns PS01008 DnaA protein signature. 437 456 - T 14-10-2018 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 MB46_16100 2b5b6fd6a87045ee91d102fd64d7e26e 484 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 10 478 32.451 T 14-10-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 MB46_16100 2b5b6fd6a87045ee91d102fd64d7e26e 484 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 176 196 7.6E-53 T 14-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like MB46_16100 2b5b6fd6a87045ee91d102fd64d7e26e 484 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 437 456 7.6E-53 T 14-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like MB46_16100 2b5b6fd6a87045ee91d102fd64d7e26e 484 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 208 222 7.6E-53 T 14-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like MB46_16100 2b5b6fd6a87045ee91d102fd64d7e26e 484 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 274 301 7.6E-53 T 14-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like MB46_16100 2b5b6fd6a87045ee91d102fd64d7e26e 484 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 240 254 7.6E-53 T 14-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like MB46_16100 2b5b6fd6a87045ee91d102fd64d7e26e 484 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 390 456 8.1E-31 T 14-10-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 MB46_16100 2b5b6fd6a87045ee91d102fd64d7e26e 484 Gene3D G3DSA:1.10.1750.10 382 483 1.0E-36 T 14-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 MB46_16100 2b5b6fd6a87045ee91d102fd64d7e26e 484 SMART SM00760 387 456 4.1E-38 T 14-10-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 MB46_16100 2b5b6fd6a87045ee91d102fd64d7e26e 484 Pfam PF00308 Bacterial dnaA protein 143 360 3.1E-97 T 14-10-2018 IPR013317 Chromosomal replication initiator protein DnaA MB46_16100 2b5b6fd6a87045ee91d102fd64d7e26e 484 Gene3D G3DSA:1.10.8.60 309 380 2.2E-24 T 14-10-2018 MB46_16100 2b5b6fd6a87045ee91d102fd64d7e26e 484 Gene3D G3DSA:3.40.50.300 134 307 5.7E-53 T 14-10-2018 MB46_16100 2b5b6fd6a87045ee91d102fd64d7e26e 484 Gene3D G3DSA:3.30.300.180 5 87 7.4E-6 T 14-10-2018 IPR038454 DnaA, N-terminal domain superfamily MB46_16100 2b5b6fd6a87045ee91d102fd64d7e26e 484 SUPERFAMILY SSF52540 143 354 7.8E-46 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_16100 2b5b6fd6a87045ee91d102fd64d7e26e 484 SUPERFAMILY SSF48295 374 479 3.4E-36 T 14-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 MB46_02935 01e508599881b992c5ea8b4f49f16962 484 SUPERFAMILY SSF49879 340 481 4.72E-10 T 14-10-2018 IPR008984 SMAD/FHA domain superfamily GO:0005515 MB46_02935 01e508599881b992c5ea8b4f49f16962 484 Gene3D G3DSA:2.60.200.20 359 483 1.9E-10 T 14-10-2018 MB46_02935 01e508599881b992c5ea8b4f49f16962 484 Pfam PF06271 RDD family 87 227 3.2E-21 T 14-10-2018 IPR010432 RDD MB46_17640 d2efec2a6d7fa3050bdddc8fd6fd0ad7 360 Gene3D G3DSA:3.20.20.120 123 353 9.5E-73 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily MB46_17640 d2efec2a6d7fa3050bdddc8fd6fd0ad7 360 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 99 124 - T 14-10-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 MB46_17640 d2efec2a6d7fa3050bdddc8fd6fd0ad7 360 Pfam PF13378 Enolase C-terminal domain-like 145 353 7.5E-60 T 14-10-2018 IPR029065 Enolase C-terminal domain-like MB46_17640 d2efec2a6d7fa3050bdddc8fd6fd0ad7 360 SUPERFAMILY SSF51604 112 353 5.37E-64 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily MB46_17640 d2efec2a6d7fa3050bdddc8fd6fd0ad7 360 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 28 124 7.0E-11 T 14-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain MB46_17640 d2efec2a6d7fa3050bdddc8fd6fd0ad7 360 SMART SM00922 143 240 6.6E-30 T 14-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal MB46_17640 d2efec2a6d7fa3050bdddc8fd6fd0ad7 360 Gene3D G3DSA:3.30.390.10 1 122 1.5E-22 T 14-10-2018 IPR029017 Enolase-like, N-terminal MB46_17640 d2efec2a6d7fa3050bdddc8fd6fd0ad7 360 SUPERFAMILY SSF54826 4 127 2.65E-20 T 14-10-2018 MB46_10270 48b591d6699d7efc7c458855f771ad8d 108 SMART SM00530 24 80 8.9E-5 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MB46_10270 48b591d6699d7efc7c458855f771ad8d 108 Pfam PF01381 Helix-turn-helix 25 78 2.1E-5 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MB46_10270 48b591d6699d7efc7c458855f771ad8d 108 Gene3D G3DSA:1.10.260.40 22 86 4.2E-9 T 14-10-2018 MB46_10270 48b591d6699d7efc7c458855f771ad8d 108 SUPERFAMILY SSF47413 24 87 3.1E-11 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MB46_02190 4690d168171636460525ec308cbb95d1 458 Hamap MF_00743 Fumarate hydratase class II [fumC]. 1 456 76.093 T 14-10-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 MB46_02190 4690d168171636460525ec308cbb95d1 458 PRINTS PR00145 Argininosuccinate lyase family signature 122 144 2.2E-5 T 14-10-2018 MB46_02190 4690d168171636460525ec308cbb95d1 458 PRINTS PR00145 Argininosuccinate lyase family signature 306 322 2.2E-5 T 14-10-2018 MB46_02190 4690d168171636460525ec308cbb95d1 458 PRINTS PR00145 Argininosuccinate lyase family signature 164 184 2.2E-5 T 14-10-2018 MB46_02190 4690d168171636460525ec308cbb95d1 458 Gene3D G3DSA:1.10.275.10 1 127 4.5E-46 T 14-10-2018 IPR024083 Fumarase/histidase, N-terminal MB46_02190 4690d168171636460525ec308cbb95d1 458 Pfam PF10415 Fumarase C C-terminus 397 455 6.4E-22 T 14-10-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 MB46_02190 4690d168171636460525ec308cbb95d1 458 Pfam PF00206 Lyase 2 331 4.6E-96 T 14-10-2018 IPR022761 Fumarate lyase, N-terminal MB46_02190 4690d168171636460525ec308cbb95d1 458 Gene3D G3DSA:1.20.200.10 128 396 1.1E-106 T 14-10-2018 MB46_02190 4690d168171636460525ec308cbb95d1 458 SUPERFAMILY SSF48557 1 451 1.4E-138 T 14-10-2018 IPR008948 L-Aspartase-like GO:0003824 MB46_02190 4690d168171636460525ec308cbb95d1 458 ProSitePatterns PS00163 Fumarate lyases signature. 306 315 - T 14-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 MB46_02190 4690d168171636460525ec308cbb95d1 458 PRINTS PR00149 Fumarate lyase superfamily signature 306 322 8.5E-31 T 14-10-2018 IPR000362 Fumarate lyase family MB46_02190 4690d168171636460525ec308cbb95d1 458 PRINTS PR00149 Fumarate lyase superfamily signature 260 287 8.5E-31 T 14-10-2018 IPR000362 Fumarate lyase family MB46_02190 4690d168171636460525ec308cbb95d1 458 PRINTS PR00149 Fumarate lyase superfamily signature 123 141 8.5E-31 T 14-10-2018 IPR000362 Fumarate lyase family MB46_02190 4690d168171636460525ec308cbb95d1 458 PRINTS PR00149 Fumarate lyase superfamily signature 169 187 8.5E-31 T 14-10-2018 IPR000362 Fumarate lyase family MB46_02190 4690d168171636460525ec308cbb95d1 458 Gene3D G3DSA:1.10.40.30 397 453 9.3E-24 T 14-10-2018 MB46_18280 ec17086a2efe1d203ada4acdae6c4a82 440 Pfam PF00463 Isocitrate lyase family 265 422 1.3E-43 T 14-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 MB46_18280 ec17086a2efe1d203ada4acdae6c4a82 440 Pfam PF00463 Isocitrate lyase family 25 263 1.8E-56 T 14-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 MB46_18280 ec17086a2efe1d203ada4acdae6c4a82 440 SUPERFAMILY SSF51621 13 439 8.07E-157 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 MB46_18280 ec17086a2efe1d203ada4acdae6c4a82 440 PIRSF PIRSF001362 11 440 1.4E-236 T 14-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 MB46_18280 ec17086a2efe1d203ada4acdae6c4a82 440 ProSitePatterns PS00161 Isocitrate lyase signature. 201 206 - T 14-10-2018 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824 MB46_18280 ec17086a2efe1d203ada4acdae6c4a82 440 Gene3D G3DSA:3.20.20.60 17 422 3.9E-172 T 14-10-2018 MB46_18280 ec17086a2efe1d203ada4acdae6c4a82 440 TIGRFAM TIGR01346 isocit_lyase: isocitrate lyase 22 263 9.3E-109 T 14-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 MB46_12460 b9c2147c0c04007574a5358d81fa76f8 193 SUPERFAMILY SSF88659 123 190 5.45E-16 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like MB46_12460 b9c2147c0c04007574a5358d81fa76f8 193 Gene3D G3DSA:1.10.1740.10 17 100 1.1E-31 T 14-10-2018 MB46_12460 b9c2147c0c04007574a5358d81fa76f8 193 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 57 89 - T 14-10-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MB46_12460 b9c2147c0c04007574a5358d81fa76f8 193 Gene3D G3DSA:1.10.10.10 101 193 9.3E-33 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_12460 b9c2147c0c04007574a5358d81fa76f8 193 Pfam PF08281 Sigma-70, region 4 134 185 4.1E-14 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MB46_12460 b9c2147c0c04007574a5358d81fa76f8 193 Pfam PF04542 Sigma-70 region 2 35 101 6.3E-16 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 MB46_12460 b9c2147c0c04007574a5358d81fa76f8 193 SUPERFAMILY SSF88946 11 109 6.67E-22 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 MB46_12460 b9c2147c0c04007574a5358d81fa76f8 193 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 31 190 1.2E-27 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 MB46_00400 e30877bdfdee74177c426464e110ab38 350 Gene3D G3DSA:1.10.3470.10 27 349 2.2E-80 T 14-10-2018 IPR037294 ABC transporter, BtuC-like MB46_00400 e30877bdfdee74177c426464e110ab38 350 Pfam PF01032 FecCD transport family 40 344 3.0E-76 T 14-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 MB46_00400 e30877bdfdee74177c426464e110ab38 350 SUPERFAMILY SSF81345 22 344 3.01E-66 T 14-10-2018 IPR037294 ABC transporter, BtuC-like MB46_04465 51ea820378bafb2c848655283045d80c 239 SUPERFAMILY SSF52540 15 231 1.3E-30 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_04465 51ea820378bafb2c848655283045d80c 239 Gene3D G3DSA:3.40.50.300 10 236 6.5E-65 T 14-10-2018 MB46_04465 51ea820378bafb2c848655283045d80c 239 Pfam PF02224 Cytidylate kinase 19 230 8.3E-52 T 14-10-2018 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 MB46_04465 51ea820378bafb2c848655283045d80c 239 TIGRFAM TIGR00017 cmk: cytidylate kinase 16 227 2.2E-48 T 14-10-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 MB46_04465 51ea820378bafb2c848655283045d80c 239 Hamap MF_00238 Cytidylate kinase [cmk]. 17 233 25.649 T 14-10-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 MB46_02620 54a59ba82119a6e0068e8285d4909a69 571 SMART SM00388 331 398 4.1E-18 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MB46_02620 54a59ba82119a6e0068e8285d4909a69 571 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 439 547 5.4E-23 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MB46_02620 54a59ba82119a6e0068e8285d4909a69 571 Gene3D G3DSA:3.30.565.10 392 548 4.6E-40 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MB46_02620 54a59ba82119a6e0068e8285d4909a69 571 PRINTS PR00344 Bacterial sensor protein C-terminal signature 493 503 2.4E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MB46_02620 54a59ba82119a6e0068e8285d4909a69 571 PRINTS PR00344 Bacterial sensor protein C-terminal signature 534 547 2.4E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MB46_02620 54a59ba82119a6e0068e8285d4909a69 571 PRINTS PR00344 Bacterial sensor protein C-terminal signature 510 528 2.4E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MB46_02620 54a59ba82119a6e0068e8285d4909a69 571 PRINTS PR00344 Bacterial sensor protein C-terminal signature 475 489 2.4E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MB46_02620 54a59ba82119a6e0068e8285d4909a69 571 Pfam PF00512 His Kinase A (phospho-acceptor) domain 331 392 3.6E-16 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MB46_02620 54a59ba82119a6e0068e8285d4909a69 571 Gene3D G3DSA:3.30.450.20 192 331 3.2E-11 T 14-10-2018 MB46_02620 54a59ba82119a6e0068e8285d4909a69 571 SMART SM00387 438 550 1.1E-32 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MB46_02620 54a59ba82119a6e0068e8285d4909a69 571 SUPERFAMILY SSF47384 318 392 3.53E-18 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MB46_02620 54a59ba82119a6e0068e8285d4909a69 571 SUPERFAMILY SSF55874 392 547 5.11E-40 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MB46_02620 54a59ba82119a6e0068e8285d4909a69 571 SUPERFAMILY SSF55785 193 323 1.15E-9 T 14-10-2018 IPR035965 PAS domain superfamily MB46_02620 54a59ba82119a6e0068e8285d4909a69 571 Gene3D G3DSA:1.10.287.130 332 391 5.3E-19 T 14-10-2018 MB46_03830 0e56728a843837763f1d1c2cbb99bcf9 93 Gene3D G3DSA:3.10.20.30 1 93 9.0E-16 T 14-10-2018 IPR012675 Beta-grasp domain superfamily MB46_03830 0e56728a843837763f1d1c2cbb99bcf9 93 Pfam PF02597 ThiS family 3 93 9.2E-9 T 14-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 MB46_03830 0e56728a843837763f1d1c2cbb99bcf9 93 SUPERFAMILY SSF54285 2 93 1.16E-11 T 14-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp MB46_10175 2c6f33f0b637ed72325ff7bff7dfc407 255 Pfam PF03932 CutC family 19 218 1.2E-59 T 14-10-2018 IPR023648 Copper homeostasis CutC domain GO:0005507|GO:0055070 Reactome: R-HSA-936837 MB46_10175 2c6f33f0b637ed72325ff7bff7dfc407 255 Hamap MF_00795 Copper homeostasis protein CutC [cutC]. 17 220 27.129 T 14-10-2018 IPR005627 Copper homeostasis protein CutC GO:0005507|GO:0055070 Reactome: R-HSA-936837 MB46_10175 2c6f33f0b637ed72325ff7bff7dfc407 255 Gene3D G3DSA:3.20.20.380 18 253 1.1E-71 T 14-10-2018 IPR036822 Copper homeostasis (CutC) domain superfamily GO:0005507|GO:0055070 Reactome: R-HSA-936837 MB46_10175 2c6f33f0b637ed72325ff7bff7dfc407 255 SUPERFAMILY SSF110395 19 223 4.32E-58 T 14-10-2018 IPR036822 Copper homeostasis (CutC) domain superfamily GO:0005507|GO:0055070 Reactome: R-HSA-936837 MB46_00895 c88f86cc9115edbf4870c2856f912a46 287 Gene3D G3DSA:2.40.30.10 13 143 1.2E-31 T 14-10-2018 MB46_00895 c88f86cc9115edbf4870c2856f912a46 287 Gene3D G3DSA:3.40.50.80 145 285 4.1E-49 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain MB46_00895 c88f86cc9115edbf4870c2856f912a46 287 SUPERFAMILY SSF63380 25 148 6.08E-10 T 14-10-2018 IPR017938 Riboflavin synthase-like beta-barrel MB46_00895 c88f86cc9115edbf4870c2856f912a46 287 Pfam PF08021 Siderophore-interacting FAD-binding domain 28 143 2.3E-32 T 14-10-2018 IPR013113 FAD-binding 9, siderophore-interacting MB46_00895 c88f86cc9115edbf4870c2856f912a46 287 Pfam PF04954 Siderophore-interacting protein 150 268 7.7E-38 T 14-10-2018 IPR007037 Siderophore-interacting protein, C-terminal domain MB46_07630 d07d306f6077395925078c79d9769a05 282 SUPERFAMILY SSF51366 17 266 1.1E-77 T 14-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 MB46_07630 d07d306f6077395925078c79d9769a05 282 Gene3D G3DSA:3.20.20.70 16 279 3.4E-88 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MB46_07630 d07d306f6077395925078c79d9769a05 282 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 28 271 31.616 T 14-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 MB46_07630 d07d306f6077395925078c79d9769a05 282 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 25 254 2.7E-67 T 14-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 MB46_07630 d07d306f6077395925078c79d9769a05 282 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 62 75 - T 14-10-2018 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 MB46_07630 d07d306f6077395925078c79d9769a05 282 Pfam PF00290 Tryptophan synthase alpha chain 24 255 3.4E-68 T 14-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 MB46_07080 ceb12a126b7e92ae5bdd8b6c50789323 365 TIGRFAM TIGR02295 HpaD: 3,4-dihydroxyphenylacetate 2,3-dioxygenase 14 309 8.2E-134 T 14-10-2018 IPR011981 3,4-dihydroxyphenylacetate 2,3-dioxygenase, Mn/Fe-type MB46_07080 ceb12a126b7e92ae5bdd8b6c50789323 365 SUPERFAMILY SSF54593 11 326 1.48E-42 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MB46_07080 ceb12a126b7e92ae5bdd8b6c50789323 365 Gene3D G3DSA:3.10.180.10 152 290 5.8E-36 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MB46_07080 ceb12a126b7e92ae5bdd8b6c50789323 365 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 19 127 6.5E-6 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MB46_07080 ceb12a126b7e92ae5bdd8b6c50789323 365 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 152 268 5.8E-11 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MB46_07080 ceb12a126b7e92ae5bdd8b6c50789323 365 Gene3D G3DSA:4.10.1270.10 291 365 7.9E-35 T 14-10-2018 MB46_07080 ceb12a126b7e92ae5bdd8b6c50789323 365 Gene3D G3DSA:3.10.180.10 4 151 2.2E-55 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MB46_11095 35c35cf08cf7a867db4b3c92ba56387d 446 Pfam PF00571 CBS domain 217 267 7.3E-6 T 14-10-2018 IPR000644 CBS domain MB46_11095 35c35cf08cf7a867db4b3c92ba56387d 446 SUPERFAMILY SSF56176 350 437 7.09E-16 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 MB46_11095 35c35cf08cf7a867db4b3c92ba56387d 446 Gene3D G3DSA:3.30.465.10 343 428 7.8E-16 T 14-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 MB46_11095 35c35cf08cf7a867db4b3c92ba56387d 446 Gene3D G3DSA:3.10.580.10 196 342 3.4E-43 T 14-10-2018 MB46_11095 35c35cf08cf7a867db4b3c92ba56387d 446 Pfam PF01595 Domain of unknown function DUF21 10 199 8.3E-34 T 14-10-2018 IPR002550 CNNM, transmembrane domain MB46_11095 35c35cf08cf7a867db4b3c92ba56387d 446 SMART SM01091 351 431 5.7E-19 T 14-10-2018 IPR005170 Transporter-associated domain MB46_11095 35c35cf08cf7a867db4b3c92ba56387d 446 Pfam PF03471 Transporter associated domain 354 428 7.3E-16 T 14-10-2018 IPR005170 Transporter-associated domain MB46_11095 35c35cf08cf7a867db4b3c92ba56387d 446 SUPERFAMILY SSF54631 206 346 3.03E-27 T 14-10-2018 MB46_09560 467c9573214083c8cb75a375f6584b78 219 Pfam PF00717 Peptidase S24-like 39 78 2.3E-9 T 14-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C MB46_09560 467c9573214083c8cb75a375f6584b78 219 Pfam PF10502 Signal peptidase, peptidase S26 102 195 4.7E-8 T 14-10-2018 IPR019533 Peptidase S26 MB46_09560 467c9573214083c8cb75a375f6584b78 219 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 111 123 1.2E-17 T 14-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 MB46_09560 467c9573214083c8cb75a375f6584b78 219 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 159 178 1.2E-17 T 14-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 MB46_09560 467c9573214083c8cb75a375f6584b78 219 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 33 49 1.2E-17 T 14-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 MB46_09560 467c9573214083c8cb75a375f6584b78 219 Gene3D G3DSA:2.10.109.10 36 76 8.4E-7 T 14-10-2018 MB46_09560 467c9573214083c8cb75a375f6584b78 219 SUPERFAMILY SSF51306 31 211 1.03E-41 T 14-10-2018 IPR036286 LexA/Signal peptidase-like superfamily MB46_09560 467c9573214083c8cb75a375f6584b78 219 Gene3D G3DSA:2.10.109.10 93 215 7.5E-18 T 14-10-2018 MB46_09560 467c9573214083c8cb75a375f6584b78 219 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 19 205 9.4E-33 T 14-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 MB46_19850 6a66344f2b35374ee68b05c963562dd2 128 SUPERFAMILY SSF142906 11 116 7.06E-33 T 14-10-2018 IPR038056 YjbR-like superfamily MB46_19850 6a66344f2b35374ee68b05c963562dd2 128 Gene3D G3DSA:3.90.1150.30 7 125 1.2E-36 T 14-10-2018 IPR038056 YjbR-like superfamily MB46_19850 6a66344f2b35374ee68b05c963562dd2 128 Pfam PF04237 YjbR 16 106 4.4E-21 T 14-10-2018 IPR007351 Uncharacterised protein YjbR MB46_19460 6bd82f5288b9f569100016577cedcc65 504 TIGRFAM TIGR04226 RrgB_K2N_iso_D2: fimbrial isopeptide formation D2 domain 190 312 5.3E-17 T 14-10-2018 IPR026466 Fimbrial isopeptide formation D2 domain MB46_19460 6bd82f5288b9f569100016577cedcc65 504 Pfam PF00746 LPXTG cell wall anchor motif 462 500 1.1E-5 T 14-10-2018 IPR019948 Gram-positive LPXTG cell wall anchor MB46_19460 6bd82f5288b9f569100016577cedcc65 504 Gene3D G3DSA:2.60.40.10 339 462 1.5E-32 T 14-10-2018 IPR013783 Immunoglobulin-like fold MB46_19460 6bd82f5288b9f569100016577cedcc65 504 Gene3D G3DSA:2.60.40.10 36 186 9.3E-28 T 14-10-2018 IPR013783 Immunoglobulin-like fold MB46_19460 6bd82f5288b9f569100016577cedcc65 504 Gene3D G3DSA:2.60.40.740 188 337 1.8E-31 T 14-10-2018 MB46_19460 6bd82f5288b9f569100016577cedcc65 504 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 467 499 2.4E-4 T 14-10-2018 MB46_06125 2be79c6f4940bcc68c2663c3d0829fd5 388 SUPERFAMILY SSF53659 11 362 1.92E-104 T 14-10-2018 MB46_06125 2be79c6f4940bcc68c2663c3d0829fd5 388 SMART SM01329 17 358 1.8E-141 T 14-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 MB46_06125 2be79c6f4940bcc68c2663c3d0829fd5 388 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 18 351 2.0E-83 T 14-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 MB46_06125 2be79c6f4940bcc68c2663c3d0829fd5 388 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 252 271 - T 14-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 MB46_06125 2be79c6f4940bcc68c2663c3d0829fd5 388 Gene3D G3DSA:3.40.718.10 12 366 7.1E-116 T 14-10-2018 MB46_12115 711622d9b9299d857118262a67f9fb04 79 Pfam PF02597 ThiS family 5 79 1.7E-13 T 14-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 MB46_12115 711622d9b9299d857118262a67f9fb04 79 Gene3D G3DSA:3.10.20.30 2 79 8.5E-20 T 14-10-2018 IPR012675 Beta-grasp domain superfamily MB46_12115 711622d9b9299d857118262a67f9fb04 79 TIGRFAM TIGR01683 thiS: thiamine biosynthesis protein ThiS 4 79 9.2E-19 T 14-10-2018 IPR010035 ThiS, thiamine-biosynthesis MB46_12115 711622d9b9299d857118262a67f9fb04 79 SUPERFAMILY SSF54285 4 79 4.74E-13 T 14-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp MB46_16580 d1f4978e4c9959cb34812fb72be822b3 437 Gene3D G3DSA:3.40.640.10 101 325 5.4E-127 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MB46_16580 d1f4978e4c9959cb34812fb72be822b3 437 Gene3D G3DSA:3.90.1150.10 58 430 5.4E-127 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MB46_16580 d1f4978e4c9959cb34812fb72be822b3 437 SUPERFAMILY SSF53383 39 432 5.51E-103 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MB46_16580 d1f4978e4c9959cb34812fb72be822b3 437 Pfam PF00155 Aminotransferase class I and II 71 426 5.6E-39 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MB46_11400 09f305a3c716cf26b0d00a528e32a4eb 332 Gene3D G3DSA:3.40.50.720 5 299 3.5E-118 T 14-10-2018 MB46_11400 09f305a3c716cf26b0d00a528e32a4eb 332 SUPERFAMILY SSF51735 1 322 2.29E-91 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_11400 09f305a3c716cf26b0d00a528e32a4eb 332 Gene3D G3DSA:3.90.25.10 185 312 3.5E-118 T 14-10-2018 MB46_11400 09f305a3c716cf26b0d00a528e32a4eb 332 Pfam PF16363 GDP-mannose 4,6 dehydratase 5 304 2.5E-77 T 14-10-2018 IPR016040 NAD(P)-binding domain MB46_11400 09f305a3c716cf26b0d00a528e32a4eb 332 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 4 318 1.3E-139 T 14-10-2018 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|KEGG: 00525+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 MB46_13745 6b51bd4390cf2bf4981973cd5205707b 516 Gene3D G3DSA:1.20.1250.20 282 504 1.0E-18 T 14-10-2018 MB46_13745 6b51bd4390cf2bf4981973cd5205707b 516 Gene3D G3DSA:1.20.1720.10 24 237 2.8E-38 T 14-10-2018 MB46_13745 6b51bd4390cf2bf4981973cd5205707b 516 Pfam PF07690 Major Facilitator Superfamily 33 418 1.9E-44 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MB46_13745 6b51bd4390cf2bf4981973cd5205707b 516 SUPERFAMILY SSF103473 13 505 1.83E-61 T 14-10-2018 IPR036259 MFS transporter superfamily MB46_12725 fd5a34cff8ad97b98bf93cb97b92a697 433 SUPERFAMILY SSF55729 1 140 7.6E-22 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase MB46_12725 fd5a34cff8ad97b98bf93cb97b92a697 433 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 198 326 4.0E-25 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MB46_12725 fd5a34cff8ad97b98bf93cb97b92a697 433 Gene3D G3DSA:3.40.630.30 5 138 2.2E-19 T 14-10-2018 MB46_12725 fd5a34cff8ad97b98bf93cb97b92a697 433 SUPERFAMILY SSF52540 156 407 5.55E-42 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_12725 fd5a34cff8ad97b98bf93cb97b92a697 433 SMART SM00382 194 329 2.1E-17 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_12725 fd5a34cff8ad97b98bf93cb97b92a697 433 Gene3D G3DSA:3.40.50.300 160 418 6.9E-48 T 14-10-2018 MB46_12725 fd5a34cff8ad97b98bf93cb97b92a697 433 ProSitePatterns PS00674 AAA-protein family signature. 297 315 - T 14-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 MB46_12725 fd5a34cff8ad97b98bf93cb97b92a697 433 Pfam PF00583 Acetyltransferase (GNAT) family 23 108 1.1E-10 T 14-10-2018 IPR000182 GNAT domain MB46_12725 fd5a34cff8ad97b98bf93cb97b92a697 433 Gene3D G3DSA:1.10.8.60 328 411 6.9E-48 T 14-10-2018 MB46_00875 099338f6465e5a9631586bf59a6953af 227 SMART SM00382 30 217 1.6E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_00875 099338f6465e5a9631586bf59a6953af 227 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_00875 099338f6465e5a9631586bf59a6953af 227 Pfam PF00005 ABC transporter 22 170 6.1E-34 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_00875 099338f6465e5a9631586bf59a6953af 227 Gene3D G3DSA:3.40.50.300 1 226 9.0E-69 T 14-10-2018 MB46_00875 099338f6465e5a9631586bf59a6953af 227 SUPERFAMILY SSF52540 1 224 1.1E-68 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_06180 135a04ef246acc6e00271643e02762ec 146 Gene3D G3DSA:1.10.287.100 96 142 5.6E-7 T 14-10-2018 MB46_06180 135a04ef246acc6e00271643e02762ec 146 Pfam PF12802 MarR family 37 88 8.4E-8 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MB46_06180 135a04ef246acc6e00271643e02762ec 146 SUPERFAMILY SSF46785 9 139 1.18E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_06180 135a04ef246acc6e00271643e02762ec 146 SMART SM00347 25 126 2.6E-7 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MB46_06180 135a04ef246acc6e00271643e02762ec 146 Gene3D G3DSA:1.10.10.10 32 95 7.0E-13 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_01670 df9f07dd3df1b35a51febf2561f9bfa9 310 Pfam PF01380 SIS domain 140 205 1.1E-5 T 14-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 MB46_01670 df9f07dd3df1b35a51febf2561f9bfa9 310 SUPERFAMILY SSF53697 17 260 1.29E-60 T 14-10-2018 MB46_01670 df9f07dd3df1b35a51febf2561f9bfa9 310 Gene3D G3DSA:3.40.50.10490 11 229 5.9E-69 T 14-10-2018 MB46_01670 df9f07dd3df1b35a51febf2561f9bfa9 310 Hamap MF_00068 N-acetylmuramic acid 6-phosphate etherase [murQ]. 13 306 38.589 T 14-10-2018 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00520+4.2.1.126 MB46_01670 df9f07dd3df1b35a51febf2561f9bfa9 310 Gene3D G3DSA:1.10.8.1080 230 307 3.0E-25 T 14-10-2018 MB46_01670 df9f07dd3df1b35a51febf2561f9bfa9 310 TIGRFAM TIGR00274 TIGR00274: N-acetylmuramic acid 6-phosphate etherase 17 306 6.4E-104 T 14-10-2018 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00520+4.2.1.126 MB46_01670 df9f07dd3df1b35a51febf2561f9bfa9 310 ProSitePatterns PS01272 Glucokinase regulatory protein family signature. 196 213 - T 14-10-2018 IPR005486 Glucokinase regulatory protein, conserved site KEGG: 00520+4.2.1.126|Reactome: R-HSA-170822|Reactome: R-HSA-5619107 MB46_08265 8748b26b77500c339094c0acf0e4b61a 580 Gene3D G3DSA:3.90.190.20 405 565 8.0E-50 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MB46_08265 8748b26b77500c339094c0acf0e4b61a 580 SUPERFAMILY SSF63418 45 134 1.57E-19 T 14-10-2018 IPR035911 MurE/MurF, N-terminal MB46_08265 8748b26b77500c339094c0acf0e4b61a 580 Pfam PF02875 Mur ligase family, glutamate ligase domain 403 487 1.8E-19 T 14-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 MB46_08265 8748b26b77500c339094c0acf0e4b61a 580 SUPERFAMILY SSF53623 146 360 3.78E-63 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 MB46_08265 8748b26b77500c339094c0acf0e4b61a 580 SUPERFAMILY SSF53244 403 563 8.55E-41 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MB46_08265 8748b26b77500c339094c0acf0e4b61a 580 Gene3D G3DSA:3.40.1190.10 145 370 8.8E-71 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 MB46_08265 8748b26b77500c339094c0acf0e4b61a 580 Pfam PF01225 Mur ligase family, catalytic domain 52 98 5.8E-11 T 14-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 MB46_08265 8748b26b77500c339094c0acf0e4b61a 580 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 26 561 30.437 T 14-10-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 MB46_08265 8748b26b77500c339094c0acf0e4b61a 580 Gene3D G3DSA:3.40.1390.10 24 135 1.3E-29 T 14-10-2018 MB46_08265 8748b26b77500c339094c0acf0e4b61a 580 Pfam PF08245 Mur ligase middle domain 152 358 2.8E-43 T 14-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 MB46_03490 1f06727bdacfc280d534ad9732dee722 294 Pfam PF00318 Ribosomal protein S2 9 225 1.3E-91 T 14-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MB46_03490 1f06727bdacfc280d534ad9732dee722 294 PRINTS PR00395 Ribosomal protein S2 signature 37 46 2.6E-38 T 14-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MB46_03490 1f06727bdacfc280d534ad9732dee722 294 PRINTS PR00395 Ribosomal protein S2 signature 176 187 2.6E-38 T 14-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MB46_03490 1f06727bdacfc280d534ad9732dee722 294 PRINTS PR00395 Ribosomal protein S2 signature 87 104 2.6E-38 T 14-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MB46_03490 1f06727bdacfc280d534ad9732dee722 294 PRINTS PR00395 Ribosomal protein S2 signature 159 176 2.6E-38 T 14-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MB46_03490 1f06727bdacfc280d534ad9732dee722 294 PRINTS PR00395 Ribosomal protein S2 signature 197 211 2.6E-38 T 14-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MB46_03490 1f06727bdacfc280d534ad9732dee722 294 PRINTS PR00395 Ribosomal protein S2 signature 6 24 2.6E-38 T 14-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MB46_03490 1f06727bdacfc280d534ad9732dee722 294 SUPERFAMILY SSF52313 6 227 6.41E-89 T 14-10-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain superfamily MB46_03490 1f06727bdacfc280d534ad9732dee722 294 Gene3D G3DSA:3.40.50.10490 10 215 8.8E-86 T 14-10-2018 MB46_03490 1f06727bdacfc280d534ad9732dee722 294 Gene3D G3DSA:1.10.287.610 97 153 8.8E-86 T 14-10-2018 MB46_03490 1f06727bdacfc280d534ad9732dee722 294 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 6 17 - T 14-10-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 MB46_03490 1f06727bdacfc280d534ad9732dee722 294 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 2 226 40.449 T 14-10-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_03490 1f06727bdacfc280d534ad9732dee722 294 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 3 225 3.2E-102 T 14-10-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_04020 7818b8c31c3bb4433ddaafcab8b99e51 400 SUPERFAMILY SSF103473 11 391 1.01E-58 T 14-10-2018 IPR036259 MFS transporter superfamily MB46_04020 7818b8c31c3bb4433ddaafcab8b99e51 400 Gene3D G3DSA:1.20.1250.20 13 390 4.3E-48 T 14-10-2018 MB46_04020 7818b8c31c3bb4433ddaafcab8b99e51 400 Pfam PF07690 Major Facilitator Superfamily 25 299 1.5E-36 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MB46_14900 b2b9ebca7c83401271756ccfc3723bdd 186 Pfam PF01872 RibD C-terminal domain 76 173 2.4E-9 T 14-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 MB46_14900 b2b9ebca7c83401271756ccfc3723bdd 186 Gene3D G3DSA:3.40.430.10 1 185 1.0E-38 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 MB46_14900 b2b9ebca7c83401271756ccfc3723bdd 186 SUPERFAMILY SSF53597 1 182 1.96E-27 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 MB46_09805 6c21585139cec8280db81bccb77fba12 801 Gene3D G3DSA:2.130.10.30 357 498 2.3E-17 T 14-10-2018 IPR009091 Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II MB46_09805 6c21585139cec8280db81bccb77fba12 801 Pfam PF13540 Regulator of chromosome condensation (RCC1) repeat 590 620 1.2E-6 T 14-10-2018 MB46_09805 6c21585139cec8280db81bccb77fba12 801 Pfam PF00415 Regulator of chromosome condensation (RCC1) repeat 407 443 2.0E-8 T 14-10-2018 IPR000408 Regulator of chromosome condensation, RCC1 MB46_09805 6c21585139cec8280db81bccb77fba12 801 Pfam PF00415 Regulator of chromosome condensation (RCC1) repeat 657 693 1.8E-4 T 14-10-2018 IPR000408 Regulator of chromosome condensation, RCC1 MB46_09805 6c21585139cec8280db81bccb77fba12 801 Pfam PF00415 Regulator of chromosome condensation (RCC1) repeat 707 748 3.4E-7 T 14-10-2018 IPR000408 Regulator of chromosome condensation, RCC1 MB46_09805 6c21585139cec8280db81bccb77fba12 801 Pfam PF00415 Regulator of chromosome condensation (RCC1) repeat 457 492 2.0E-6 T 14-10-2018 IPR000408 Regulator of chromosome condensation, RCC1 MB46_09805 6c21585139cec8280db81bccb77fba12 801 Pfam PF00415 Regulator of chromosome condensation (RCC1) repeat 508 554 3.1E-8 T 14-10-2018 IPR000408 Regulator of chromosome condensation, RCC1 MB46_09805 6c21585139cec8280db81bccb77fba12 801 SUPERFAMILY SSF50985 388 694 1.9E-62 T 14-10-2018 IPR009091 Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II MB46_09805 6c21585139cec8280db81bccb77fba12 801 Gene3D G3DSA:2.130.10.30 500 696 6.1E-48 T 14-10-2018 IPR009091 Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II MB46_09805 6c21585139cec8280db81bccb77fba12 801 Gene3D G3DSA:2.130.10.30 697 799 3.3E-18 T 14-10-2018 IPR009091 Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II MB46_09805 6c21585139cec8280db81bccb77fba12 801 PRINTS PR00633 Chromosome condensation regulator RCC1 signature 545 561 1.4E-10 T 14-10-2018 IPR000408 Regulator of chromosome condensation, RCC1 MB46_09805 6c21585139cec8280db81bccb77fba12 801 PRINTS PR00633 Chromosome condensation regulator RCC1 signature 460 476 1.4E-10 T 14-10-2018 IPR000408 Regulator of chromosome condensation, RCC1 MB46_09805 6c21585139cec8280db81bccb77fba12 801 PRINTS PR00633 Chromosome condensation regulator RCC1 signature 409 425 1.4E-10 T 14-10-2018 IPR000408 Regulator of chromosome condensation, RCC1 MB46_09805 6c21585139cec8280db81bccb77fba12 801 PRINTS PR00633 Chromosome condensation regulator RCC1 signature 703 724 1.4E-10 T 14-10-2018 IPR000408 Regulator of chromosome condensation, RCC1 MB46_18025 4eca74859bb6e652d030df591bbfc41e 217 Pfam PF04167 Protein of unknown function (DUF402) 91 154 1.1E-10 T 14-10-2018 IPR007295 Domain of unknown function DUF402 MB46_18025 4eca74859bb6e652d030df591bbfc41e 217 SUPERFAMILY SSF159234 33 203 1.83E-26 T 14-10-2018 IPR035930 FomD-like superfamily MB46_18025 4eca74859bb6e652d030df591bbfc41e 217 Gene3D G3DSA:2.40.380.10 7 201 3.8E-57 T 14-10-2018 IPR035930 FomD-like superfamily MB46_09665 6448033132bc8ca3b7ac5f20b83ff0ef 397 Gene3D G3DSA:3.40.50.300 193 385 9.3E-100 T 14-10-2018 MB46_09665 6448033132bc8ca3b7ac5f20b83ff0ef 397 Pfam PF02881 SRP54-type protein, helical bundle domain 111 176 3.5E-12 T 14-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MB46_09665 6448033132bc8ca3b7ac5f20b83ff0ef 397 SUPERFAMILY SSF52540 191 396 1.99E-47 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_09665 6448033132bc8ca3b7ac5f20b83ff0ef 397 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 123 397 58.749 T 14-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 MB46_09665 6448033132bc8ca3b7ac5f20b83ff0ef 397 SMART SM00382 196 347 1.1E-7 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_09665 6448033132bc8ca3b7ac5f20b83ff0ef 397 Gene3D G3DSA:1.20.120.140 99 395 9.3E-100 T 14-10-2018 MB46_09665 6448033132bc8ca3b7ac5f20b83ff0ef 397 SMART SM00963 100 180 2.9E-21 T 14-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MB46_09665 6448033132bc8ca3b7ac5f20b83ff0ef 397 SUPERFAMILY SSF47364 96 174 3.66E-18 T 14-10-2018 IPR036225 SRP/SRP receptor, N-terminal Reactome: R-HSA-1799339 MB46_09665 6448033132bc8ca3b7ac5f20b83ff0ef 397 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 370 383 - T 14-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MB46_09665 6448033132bc8ca3b7ac5f20b83ff0ef 397 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 124 396 2.4E-103 T 14-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 MB46_09665 6448033132bc8ca3b7ac5f20b83ff0ef 397 Pfam PF00448 SRP54-type protein, GTPase domain 197 396 1.9E-72 T 14-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MB46_09665 6448033132bc8ca3b7ac5f20b83ff0ef 397 SMART SM00962 197 397 9.9E-103 T 14-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MB46_02000 34dfcbf4bfb84306d84b640602e7ec2f 426 SUPERFAMILY SSF54826 3 138 9.14E-57 T 14-10-2018 MB46_02000 34dfcbf4bfb84306d84b640602e7ec2f 426 SUPERFAMILY SSF51604 138 422 1.98E-129 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily MB46_02000 34dfcbf4bfb84306d84b640602e7ec2f 426 PRINTS PR00148 Enolase signature 309 320 2.3E-47 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MB46_02000 34dfcbf4bfb84306d84b640602e7ec2f 426 PRINTS PR00148 Enolase signature 332 346 2.3E-47 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MB46_02000 34dfcbf4bfb84306d84b640602e7ec2f 426 PRINTS PR00148 Enolase signature 361 378 2.3E-47 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MB46_02000 34dfcbf4bfb84306d84b640602e7ec2f 426 PRINTS PR00148 Enolase signature 37 51 2.3E-47 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MB46_02000 34dfcbf4bfb84306d84b640602e7ec2f 426 PRINTS PR00148 Enolase signature 107 123 2.3E-47 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MB46_02000 34dfcbf4bfb84306d84b640602e7ec2f 426 PRINTS PR00148 Enolase signature 161 174 2.3E-47 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MB46_02000 34dfcbf4bfb84306d84b640602e7ec2f 426 SMART SM01193 4 134 1.8E-95 T 14-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MB46_02000 34dfcbf4bfb84306d84b640602e7ec2f 426 ProSitePatterns PS00164 Enolase signature. 332 345 - T 14-10-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MB46_02000 34dfcbf4bfb84306d84b640602e7ec2f 426 Pfam PF00113 Enolase, C-terminal TIM barrel domain 140 420 2.0E-134 T 14-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MB46_02000 34dfcbf4bfb84306d84b640602e7ec2f 426 PIRSF PIRSF001400 1 422 6.0E-191 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MB46_02000 34dfcbf4bfb84306d84b640602e7ec2f 426 Gene3D G3DSA:3.20.20.120 128 424 7.8E-136 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily MB46_02000 34dfcbf4bfb84306d84b640602e7ec2f 426 SMART SM01192 139 423 4.2E-223 T 14-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MB46_02000 34dfcbf4bfb84306d84b640602e7ec2f 426 Pfam PF03952 Enolase, N-terminal domain 4 134 7.9E-60 T 14-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MB46_02000 34dfcbf4bfb84306d84b640602e7ec2f 426 Gene3D G3DSA:3.30.390.10 1 127 7.5E-55 T 14-10-2018 IPR029017 Enolase-like, N-terminal MB46_02000 34dfcbf4bfb84306d84b640602e7ec2f 426 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 423 1.1E-208 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MB46_02000 34dfcbf4bfb84306d84b640602e7ec2f 426 Hamap MF_00318 Enolase [eno]. 2 409 45.802 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MB46_10855 c547411a1e523d63dcdbb5b68c430dd0 271 Hamap MF_01416 ATP synthase subunit delta [atpD]. 84 271 13.217 T 14-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MB46_10855 c547411a1e523d63dcdbb5b68c430dd0 271 Pfam PF00213 ATP synthase delta (OSCP) subunit 102 269 3.0E-24 T 14-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MB46_10855 c547411a1e523d63dcdbb5b68c430dd0 271 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 116 269 2.0E-16 T 14-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MB46_15475 9d045bbf6f71072dcf4622bb56c43747 128 Gene3D G3DSA:3.30.1130.10 4 122 2.4E-39 T 14-10-2018 MB46_15475 9d045bbf6f71072dcf4622bb56c43747 128 Pfam PF02152 Dihydroneopterin aldolase 7 118 6.5E-32 T 14-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 MB46_15475 9d045bbf6f71072dcf4622bb56c43747 128 SMART SM00905 7 120 1.1E-43 T 14-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 MB46_15475 9d045bbf6f71072dcf4622bb56c43747 128 TIGRFAM TIGR00526 folB_dom: FolB domain 5 122 1.6E-28 T 14-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 MB46_15475 9d045bbf6f71072dcf4622bb56c43747 128 SUPERFAMILY SSF55620 5 122 1.67E-33 T 14-10-2018 MB46_15475 9d045bbf6f71072dcf4622bb56c43747 128 TIGRFAM TIGR00525 folB: dihydroneopterin aldolase 7 119 1.3E-32 T 14-10-2018 IPR006156 Dihydroneopterin aldolase GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 MB46_17045 d530017d1281e64bb080e697d54b6f07 492 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 22 489 1.7E-100 T 14-10-2018 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 MB46_17045 d530017d1281e64bb080e697d54b6f07 492 SUPERFAMILY SSF56024 108 320 7.33E-44 T 14-10-2018 MB46_17045 d530017d1281e64bb080e697d54b6f07 492 SUPERFAMILY SSF56024 279 477 4.26E-45 T 14-10-2018 MB46_17045 d530017d1281e64bb080e697d54b6f07 492 Pfam PF13396 Phospholipase_D-nuclease N-terminal 28 65 3.2E-7 T 14-10-2018 IPR027379 Cardiolipin synthase N-terminal MB46_17045 d530017d1281e64bb080e697d54b6f07 492 SMART SM00155 405 432 0.0014 T 14-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 MB46_17045 d530017d1281e64bb080e697d54b6f07 492 SMART SM00155 224 251 0.022 T 14-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 MB46_17045 d530017d1281e64bb080e697d54b6f07 492 Gene3D G3DSA:3.30.870.10 305 492 5.3E-27 T 14-10-2018 MB46_17045 d530017d1281e64bb080e697d54b6f07 492 Gene3D G3DSA:3.30.870.10 118 304 1.8E-36 T 14-10-2018 MB46_17045 d530017d1281e64bb080e697d54b6f07 492 Pfam PF13091 PLD-like domain 142 254 1.2E-11 T 14-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 MB46_17045 d530017d1281e64bb080e697d54b6f07 492 Pfam PF13091 PLD-like domain 334 454 5.3E-23 T 14-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 MB46_06095 1175d01cc24aef5a20c8cafb7be1df59 315 SUPERFAMILY SSF161098 89 295 1.57E-18 T 14-10-2018 IPR035906 MetI-like superfamily MB46_06095 1175d01cc24aef5a20c8cafb7be1df59 315 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 313 5.4E-33 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_06095 1175d01cc24aef5a20c8cafb7be1df59 315 Gene3D G3DSA:1.10.3720.10 85 307 2.6E-21 T 14-10-2018 IPR035906 MetI-like superfamily MB46_16415 e8323e76d22f8201408719c35118d13a 92 PRINTS PR00107 Phosphocarrier protein signature 42 57 3.1E-9 T 14-10-2018 IPR000032 Phosphocarrier protein HPr-like MB46_16415 e8323e76d22f8201408719c35118d13a 92 PRINTS PR00107 Phosphocarrier protein signature 13 29 3.1E-9 T 14-10-2018 IPR000032 Phosphocarrier protein HPr-like MB46_16415 e8323e76d22f8201408719c35118d13a 92 PRINTS PR00107 Phosphocarrier protein signature 57 74 3.1E-9 T 14-10-2018 IPR000032 Phosphocarrier protein HPr-like MB46_16415 e8323e76d22f8201408719c35118d13a 92 SUPERFAMILY SSF55594 1 90 1.06E-20 T 14-10-2018 IPR035895 HPr-like superfamily MB46_16415 e8323e76d22f8201408719c35118d13a 92 Pfam PF00381 PTS HPr component phosphorylation site 3 86 4.3E-23 T 14-10-2018 IPR000032 Phosphocarrier protein HPr-like MB46_16415 e8323e76d22f8201408719c35118d13a 92 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 13 20 - T 14-10-2018 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site MB46_16415 e8323e76d22f8201408719c35118d13a 92 Gene3D G3DSA:3.30.1340.10 1 90 2.9E-23 T 14-10-2018 IPR035895 HPr-like superfamily MB46_16415 e8323e76d22f8201408719c35118d13a 92 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 1 86 7.5E-24 T 14-10-2018 IPR000032 Phosphocarrier protein HPr-like MB46_11025 43692b7a60205b81929f30cfbb26ae97 186 SUPERFAMILY SSF46689 14 80 4.24E-13 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MB46_11025 43692b7a60205b81929f30cfbb26ae97 186 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 65 7.0E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MB46_11025 43692b7a60205b81929f30cfbb26ae97 186 Gene3D G3DSA:1.10.357.10 12 185 1.1E-27 T 14-10-2018 MB46_11025 43692b7a60205b81929f30cfbb26ae97 186 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 1.1E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MB46_11025 43692b7a60205b81929f30cfbb26ae97 186 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 1.1E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MB46_12540 c54d9449d48d73130d80359f25fc79fd 308 Gene3D G3DSA:1.10.3720.10 85 301 2.7E-23 T 14-10-2018 IPR035906 MetI-like superfamily MB46_12540 c54d9449d48d73130d80359f25fc79fd 308 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 307 3.2E-37 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_12540 c54d9449d48d73130d80359f25fc79fd 308 SUPERFAMILY SSF161098 91 289 1.06E-16 T 14-10-2018 IPR035906 MetI-like superfamily MB46_01580 76739922a0c23b0d81b5589404496d45 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 14-10-2018 IPR019844 Cold-shock conserved site MB46_01580 76739922a0c23b0d81b5589404496d45 67 SUPERFAMILY SSF50249 1 66 1.24E-25 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold MB46_01580 76739922a0c23b0d81b5589404496d45 67 Gene3D G3DSA:2.40.50.140 1 67 3.9E-31 T 14-10-2018 MB46_01580 76739922a0c23b0d81b5589404496d45 67 PIRSF PIRSF002599 1 67 7.1E-27 T 14-10-2018 IPR012156 Cold shock, CspA GO:0003676 MB46_01580 76739922a0c23b0d81b5589404496d45 67 SMART SM00357 3 67 1.2E-29 T 14-10-2018 IPR011129 Cold shock domain GO:0003676 MB46_01580 76739922a0c23b0d81b5589404496d45 67 PRINTS PR00050 Cold shock protein signature 25 34 2.4E-18 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MB46_01580 76739922a0c23b0d81b5589404496d45 67 PRINTS PR00050 Cold shock protein signature 40 58 2.4E-18 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MB46_01580 76739922a0c23b0d81b5589404496d45 67 PRINTS PR00050 Cold shock protein signature 4 19 2.4E-18 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MB46_01580 76739922a0c23b0d81b5589404496d45 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 66 1.0E-31 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MB46_09755 bd29cbbed198c7bb15c01b41595d53b5 308 Gene3D G3DSA:1.10.8.50 167 306 7.7E-43 T 14-10-2018 MB46_09755 bd29cbbed198c7bb15c01b41595d53b5 308 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 1 305 1.1E-81 T 14-10-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 MB46_09755 bd29cbbed198c7bb15c01b41595d53b5 308 SUPERFAMILY SSF46946 164 254 8.98E-26 T 14-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 MB46_09755 bd29cbbed198c7bb15c01b41595d53b5 308 SUPERFAMILY SSF57716 257 305 1.71E-16 T 14-10-2018 MB46_09755 bd29cbbed198c7bb15c01b41595d53b5 308 Pfam PF06827 Zinc finger found in FPG and IleRS 278 305 7.1E-12 T 14-10-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 MB46_09755 bd29cbbed198c7bb15c01b41595d53b5 308 SUPERFAMILY SSF81624 2 134 1.7E-32 T 14-10-2018 IPR035937 MutM-like, N-terminal MB46_09755 bd29cbbed198c7bb15c01b41595d53b5 308 Gene3D G3DSA:3.20.190.10 2 140 6.9E-35 T 14-10-2018 IPR035937 MutM-like, N-terminal MB46_09755 bd29cbbed198c7bb15c01b41595d53b5 308 SMART SM00898 2 132 1.2E-42 T 14-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 MB46_09755 bd29cbbed198c7bb15c01b41595d53b5 308 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 165 252 1.6E-21 T 14-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 MB46_09755 bd29cbbed198c7bb15c01b41595d53b5 308 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 131 8.7E-34 T 14-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 MB46_09755 bd29cbbed198c7bb15c01b41595d53b5 308 Hamap MF_00103 Formamidopyrimidine-DNA glycosylase [mutM]. 1 306 39.66 T 14-10-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 MB46_09755 bd29cbbed198c7bb15c01b41595d53b5 308 SMART SM01232 165 257 3.3E-38 T 14-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 MB46_09755 bd29cbbed198c7bb15c01b41595d53b5 308 ProSitePatterns PS01242 Zinc finger FPG-type signature. 281 305 - T 14-10-2018 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 MB46_06655 e5648a74ab9984659b6b2fa33e98eedc 121 Gene3D G3DSA:3.30.720.110 65 121 6.4E-26 T 14-10-2018 MB46_06655 e5648a74ab9984659b6b2fa33e98eedc 121 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 116 2.1E-9 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MB46_06655 e5648a74ab9984659b6b2fa33e98eedc 121 PIRSF PIRSF039020 1 121 1.4E-43 T 14-10-2018 IPR026275 Glyoxalase/dioxygenase/EhpR MB46_06655 e5648a74ab9984659b6b2fa33e98eedc 121 Gene3D G3DSA:3.30.720.120 1 52 3.3E-23 T 14-10-2018 MB46_06655 e5648a74ab9984659b6b2fa33e98eedc 121 SUPERFAMILY SSF54593 7 118 6.71E-21 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MB46_08045 5900c6885a60c7612661924c3ed34c98 505 SUPERFAMILY SSF52949 20 158 1.53E-14 T 14-10-2018 MB46_08045 5900c6885a60c7612661924c3ed34c98 505 Gene3D G3DSA:3.40.220.10 4 160 3.0E-19 T 14-10-2018 MB46_08045 5900c6885a60c7612661924c3ed34c98 505 Gene3D G3DSA:3.40.630.10 164 504 3.7E-131 T 14-10-2018 MB46_08045 5900c6885a60c7612661924c3ed34c98 505 PRINTS PR00481 Cytosol aminopeptidase signature 318 339 1.9E-50 T 14-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 MB46_08045 5900c6885a60c7612661924c3ed34c98 505 PRINTS PR00481 Cytosol aminopeptidase signature 259 276 1.9E-50 T 14-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 MB46_08045 5900c6885a60c7612661924c3ed34c98 505 PRINTS PR00481 Cytosol aminopeptidase signature 281 302 1.9E-50 T 14-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 MB46_08045 5900c6885a60c7612661924c3ed34c98 505 PRINTS PR00481 Cytosol aminopeptidase signature 368 383 1.9E-50 T 14-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 MB46_08045 5900c6885a60c7612661924c3ed34c98 505 PRINTS PR00481 Cytosol aminopeptidase signature 340 360 1.9E-50 T 14-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 MB46_08045 5900c6885a60c7612661924c3ed34c98 505 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 184 494 9.5E-119 T 14-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 MB46_08045 5900c6885a60c7612661924c3ed34c98 505 SUPERFAMILY SSF53187 178 500 3.77E-112 T 14-10-2018 MB46_08045 5900c6885a60c7612661924c3ed34c98 505 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 344 351 - T 14-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 MB46_08045 5900c6885a60c7612661924c3ed34c98 505 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 7 502 33.661 T 14-10-2018 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 MB46_08045 5900c6885a60c7612661924c3ed34c98 505 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 40 145 5.9E-14 T 14-10-2018 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 MB46_18830 eba063c6ffe6020a35a8c36bcf1564e5 695 ProSitePatterns PS00690 DEAH-box subfamily ATP-dependent helicases signature. 135 144 - T 14-10-2018 IPR002464 DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site MB46_18830 eba063c6ffe6020a35a8c36bcf1564e5 695 SUPERFAMILY SSF52540 58 347 2.23E-51 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_18830 eba063c6ffe6020a35a8c36bcf1564e5 695 Pfam PF00271 Helicase conserved C-terminal domain 229 326 3.5E-13 T 14-10-2018 IPR001650 Helicase, C-terminal MB46_18830 eba063c6ffe6020a35a8c36bcf1564e5 695 SUPERFAMILY SSF53271 551 692 1.14E-5 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like MB46_18830 eba063c6ffe6020a35a8c36bcf1564e5 695 SMART SM00490 246 327 5.0E-21 T 14-10-2018 IPR001650 Helicase, C-terminal MB46_18830 eba063c6ffe6020a35a8c36bcf1564e5 695 Gene3D G3DSA:3.40.50.300 1 197 1.1E-53 T 14-10-2018 MB46_18830 eba063c6ffe6020a35a8c36bcf1564e5 695 Pfam PF16124 RecQ zinc-binding 424 469 3.3E-6 T 14-10-2018 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain MB46_18830 eba063c6ffe6020a35a8c36bcf1564e5 695 Pfam PF00270 DEAD/DEAH box helicase 16 184 1.2E-17 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MB46_18830 eba063c6ffe6020a35a8c36bcf1564e5 695 SMART SM00487 9 208 1.4E-22 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MB46_18830 eba063c6ffe6020a35a8c36bcf1564e5 695 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 12 345 8.4E-67 T 14-10-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 MB46_05850 8d3caa7ac2eb9d7d45652d40f96c0141 570 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 298 315 1.6E-34 T 14-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MB46_05850 8d3caa7ac2eb9d7d45652d40f96c0141 570 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 337 353 1.6E-34 T 14-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MB46_05850 8d3caa7ac2eb9d7d45652d40f96c0141 570 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 430 443 1.6E-34 T 14-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MB46_05850 8d3caa7ac2eb9d7d45652d40f96c0141 570 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 404 419 1.6E-34 T 14-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MB46_05850 8d3caa7ac2eb9d7d45652d40f96c0141 570 Hamap MF_01953 Urease subunit alpha [ureC]. 3 570 55.911 T 14-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MB46_05850 8d3caa7ac2eb9d7d45652d40f96c0141 570 Pfam PF01979 Amidohydrolase family 128 454 6.6E-74 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 MB46_05850 8d3caa7ac2eb9d7d45652d40f96c0141 570 SUPERFAMILY SSF51556 133 570 6.27E-192 T 14-10-2018 IPR032466 Metal-dependent hydrolase MB46_05850 8d3caa7ac2eb9d7d45652d40f96c0141 570 TIGRFAM TIGR01792 urease_alph: urease, alpha subunit 5 570 9.4E-291 T 14-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MB46_05850 8d3caa7ac2eb9d7d45652d40f96c0141 570 ProSitePatterns PS01120 Urease nickel ligands signature. 130 143 - T 14-10-2018 IPR029754 Urease nickel binding site GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MB46_05850 8d3caa7ac2eb9d7d45652d40f96c0141 570 Pfam PF00449 Urease alpha-subunit, N-terminal domain 4 122 2.5E-52 T 14-10-2018 IPR011612 Urease alpha-subunit, N-terminal domain KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MB46_05850 8d3caa7ac2eb9d7d45652d40f96c0141 570 SUPERFAMILY SSF51338 425 477 1.82E-5 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 MB46_05850 8d3caa7ac2eb9d7d45652d40f96c0141 570 Gene3D G3DSA:3.20.20.140 132 570 6.8E-284 T 14-10-2018 MB46_05850 8d3caa7ac2eb9d7d45652d40f96c0141 570 ProSitePatterns PS00145 Urease active site. 320 336 - T 14-10-2018 IPR017950 Urease active site GO:0009039 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MB46_05850 8d3caa7ac2eb9d7d45652d40f96c0141 570 SUPERFAMILY SSF51338 4 180 1.54E-57 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 MB46_05850 8d3caa7ac2eb9d7d45652d40f96c0141 570 Gene3D G3DSA:2.30.40.10 6 483 6.8E-284 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 MB46_02330 dca0e1b9e8c5c1a121141b90488f5d98 487 Pfam PF00437 Type II/IV secretion system protein 132 407 1.2E-85 T 14-10-2018 IPR001482 Type II/IV secretion system protein MB46_02330 dca0e1b9e8c5c1a121141b90488f5d98 487 Gene3D G3DSA:3.40.50.300 228 454 3.5E-73 T 14-10-2018 MB46_02330 dca0e1b9e8c5c1a121141b90488f5d98 487 SUPERFAMILY SSF52540 112 424 1.09E-62 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_02330 dca0e1b9e8c5c1a121141b90488f5d98 487 Gene3D G3DSA:3.30.450.380 41 226 1.8E-44 T 14-10-2018 MB46_09465 15178c9ab5527d1a5cea640953ea43f5 913 SUPERFAMILY SSF52518 490 719 6.83E-85 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold MB46_09465 15178c9ab5527d1a5cea640953ea43f5 913 TIGRFAM TIGR00759 aceE: pyruvate dehydrogenase (acetyl-transferring), homodimeric type 18 900 0.0 T 14-10-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 MB46_09465 15178c9ab5527d1a5cea640953ea43f5 913 Gene3D G3DSA:3.40.50.920 727 904 2.4E-66 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 MB46_09465 15178c9ab5527d1a5cea640953ea43f5 913 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 148 309 5.3E-10 T 14-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 MB46_09465 15178c9ab5527d1a5cea640953ea43f5 913 Gene3D G3DSA:3.40.50.970 489 725 3.4E-100 T 14-10-2018 MB46_09465 15178c9ab5527d1a5cea640953ea43f5 913 PIRSF PIRSF000156 9 907 0.0 T 14-10-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 MB46_09465 15178c9ab5527d1a5cea640953ea43f5 913 Gene3D G3DSA:3.40.50.970 68 488 1.1E-132 T 14-10-2018 MB46_09465 15178c9ab5527d1a5cea640953ea43f5 913 SUPERFAMILY SSF52518 69 485 7.71E-129 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold MB46_09465 15178c9ab5527d1a5cea640953ea43f5 913 SUPERFAMILY SSF52922 723 898 5.85E-55 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 MB46_13975 387e8f9b2234672f958b045da9322796 434 SUPERFAMILY SSF103473 14 423 1.96E-45 T 14-10-2018 IPR036259 MFS transporter superfamily MB46_13975 387e8f9b2234672f958b045da9322796 434 Gene3D G3DSA:1.20.1250.20 16 217 3.7E-16 T 14-10-2018 MB46_13975 387e8f9b2234672f958b045da9322796 434 Pfam PF07690 Major Facilitator Superfamily 246 429 4.0E-14 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MB46_13975 387e8f9b2234672f958b045da9322796 434 Pfam PF07690 Major Facilitator Superfamily 30 242 4.4E-19 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MB46_13975 387e8f9b2234672f958b045da9322796 434 Gene3D G3DSA:1.20.1250.20 232 430 1.9E-17 T 14-10-2018 MB46_19765 582e9efa2f6305b368f3375a006b26cb 204 Pfam PF00239 Resolvase, N terminal domain 3 143 4.2E-43 T 14-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 MB46_19765 582e9efa2f6305b368f3375a006b26cb 204 SUPERFAMILY SSF46689 145 187 5.39E-5 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MB46_19765 582e9efa2f6305b368f3375a006b26cb 204 Gene3D G3DSA:3.40.50.1390 1 132 3.3E-43 T 14-10-2018 MB46_19765 582e9efa2f6305b368f3375a006b26cb 204 ProSitePatterns PS00398 Site-specific recombinases signature 2. 59 71 - T 14-10-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 MB46_19765 582e9efa2f6305b368f3375a006b26cb 204 SUPERFAMILY SSF53041 1 142 1.24E-41 T 14-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 MB46_19765 582e9efa2f6305b368f3375a006b26cb 204 SMART SM00857 2 143 7.9E-57 T 14-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 MB46_09985 c58e990e59235406abc7c5896dabfb0b 110 SUPERFAMILY SSF46785 9 103 9.9E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_09985 c58e990e59235406abc7c5896dabfb0b 110 Pfam PF12840 Helix-turn-helix domain 12 71 5.5E-10 T 14-10-2018 MB46_09985 c58e990e59235406abc7c5896dabfb0b 110 SMART SM00418 13 91 1.6E-13 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MB46_09985 c58e990e59235406abc7c5896dabfb0b 110 Gene3D G3DSA:1.10.10.10 5 110 4.5E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_01675 0215944ce6b8a1df4267cf8e62c156a9 291 SUPERFAMILY SSF53697 114 282 1.21E-35 T 14-10-2018 MB46_01675 0215944ce6b8a1df4267cf8e62c156a9 291 Gene3D G3DSA:3.40.50.10490 104 283 5.2E-41 T 14-10-2018 MB46_01675 0215944ce6b8a1df4267cf8e62c156a9 291 SUPERFAMILY SSF46689 2 76 9.32E-17 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MB46_01675 0215944ce6b8a1df4267cf8e62c156a9 291 Pfam PF01418 Helix-turn-helix domain, rpiR family 4 74 2.7E-15 T 14-10-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 MB46_01675 0215944ce6b8a1df4267cf8e62c156a9 291 Pfam PF01380 SIS domain 134 261 1.1E-20 T 14-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 MB46_01675 0215944ce6b8a1df4267cf8e62c156a9 291 Gene3D G3DSA:1.10.10.10 2 79 2.4E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_10470 523cefc513a84f6665fcab6d2e40dbe0 496 Pfam PF02838 Glycosyl hydrolase family 20, domain 2 22 145 2.2E-17 T 14-10-2018 IPR015882 Beta-hexosaminidase, bacterial type, N-terminal MB46_10470 523cefc513a84f6665fcab6d2e40dbe0 496 Gene3D G3DSA:3.20.20.80 140 473 9.6E-67 T 14-10-2018 MB46_10470 523cefc513a84f6665fcab6d2e40dbe0 496 Gene3D G3DSA:3.30.379.10 10 139 7.3E-23 T 14-10-2018 IPR029018 Beta-hexosaminidase-like, domain 2 MB46_10470 523cefc513a84f6665fcab6d2e40dbe0 496 PRINTS PR00738 Glycosyl hydrolase family 20 signature 296 309 2.1E-20 T 14-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 MB46_10470 523cefc513a84f6665fcab6d2e40dbe0 496 PRINTS PR00738 Glycosyl hydrolase family 20 signature 236 253 2.1E-20 T 14-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 MB46_10470 523cefc513a84f6665fcab6d2e40dbe0 496 PRINTS PR00738 Glycosyl hydrolase family 20 signature 142 159 2.1E-20 T 14-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 MB46_10470 523cefc513a84f6665fcab6d2e40dbe0 496 PRINTS PR00738 Glycosyl hydrolase family 20 signature 110 130 2.1E-20 T 14-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 MB46_10470 523cefc513a84f6665fcab6d2e40dbe0 496 PRINTS PR00738 Glycosyl hydrolase family 20 signature 171 192 2.1E-20 T 14-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 MB46_10470 523cefc513a84f6665fcab6d2e40dbe0 496 PRINTS PR00738 Glycosyl hydrolase family 20 signature 430 446 2.1E-20 T 14-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 MB46_10470 523cefc513a84f6665fcab6d2e40dbe0 496 SUPERFAMILY SSF55545 21 146 4.32E-17 T 14-10-2018 IPR029018 Beta-hexosaminidase-like, domain 2 MB46_10470 523cefc513a84f6665fcab6d2e40dbe0 496 Pfam PF00728 Glycosyl hydrolase family 20, catalytic domain 148 442 3.6E-26 T 14-10-2018 IPR015883 Glycoside hydrolase family 20, catalytic domain GO:0004553|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883 MB46_10470 523cefc513a84f6665fcab6d2e40dbe0 496 SUPERFAMILY SSF51445 148 469 1.9E-64 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily MB46_00765 b99490e8e9ee7604ceba4bc59c34ed7d 282 SUPERFAMILY SSF63520 59 165 2.88E-18 T 14-10-2018 IPR036634 PRD domain superfamily GO:0006355 MB46_00765 b99490e8e9ee7604ceba4bc59c34ed7d 282 Pfam PF03123 CAT RNA binding domain 1 55 1.1E-17 T 14-10-2018 IPR004341 CAT RNA-binding domain GO:0003723 MB46_00765 b99490e8e9ee7604ceba4bc59c34ed7d 282 SMART SM01061 1 61 9.4E-22 T 14-10-2018 IPR004341 CAT RNA-binding domain GO:0003723 MB46_00765 b99490e8e9ee7604ceba4bc59c34ed7d 282 Pfam PF00874 PRD domain 184 275 1.5E-11 T 14-10-2018 IPR011608 PRD domain GO:0006355 MB46_00765 b99490e8e9ee7604ceba4bc59c34ed7d 282 Pfam PF00874 PRD domain 86 165 1.1E-14 T 14-10-2018 IPR011608 PRD domain GO:0006355 MB46_00765 b99490e8e9ee7604ceba4bc59c34ed7d 282 Gene3D G3DSA:1.10.1790.10 171 280 3.8E-22 T 14-10-2018 MB46_00765 b99490e8e9ee7604ceba4bc59c34ed7d 282 Gene3D G3DSA:2.30.24.10 1 57 1.1E-17 T 14-10-2018 IPR036650 CAT RNA-binding domain superfamily GO:0003723 MB46_00765 b99490e8e9ee7604ceba4bc59c34ed7d 282 Gene3D G3DSA:1.10.1790.10 67 168 4.7E-23 T 14-10-2018 MB46_00765 b99490e8e9ee7604ceba4bc59c34ed7d 282 SUPERFAMILY SSF63520 174 277 1.06E-18 T 14-10-2018 IPR036634 PRD domain superfamily GO:0006355 MB46_00765 b99490e8e9ee7604ceba4bc59c34ed7d 282 SUPERFAMILY SSF50151 1 55 3.4E-13 T 14-10-2018 IPR036650 CAT RNA-binding domain superfamily GO:0003723 MB46_01405 a8bb236707652b36efc5afcfbcc533ab 407 Pfam PF09339 IclR helix-turn-helix domain 27 64 6.1E-5 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 MB46_01405 a8bb236707652b36efc5afcfbcc533ab 407 Gene3D G3DSA:3.30.420.40 97 385 1.4E-67 T 14-10-2018 MB46_01405 a8bb236707652b36efc5afcfbcc533ab 407 Gene3D G3DSA:1.10.10.10 7 82 9.5E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_01405 a8bb236707652b36efc5afcfbcc533ab 407 SUPERFAMILY SSF46785 16 80 5.85E-13 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_01405 a8bb236707652b36efc5afcfbcc533ab 407 Pfam PF00480 ROK family 97 388 1.1E-46 T 14-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 MB46_01405 a8bb236707652b36efc5afcfbcc533ab 407 SUPERFAMILY SSF53067 90 390 3.13E-41 T 14-10-2018 MB46_01405 a8bb236707652b36efc5afcfbcc533ab 407 Gene3D G3DSA:3.30.420.40 211 375 1.4E-67 T 14-10-2018 MB46_02095 91d8fd0b5c9324bae1c9a1b1f73f565a 300 TIGRFAM TIGR03446 mycothiol_Mca: mycothiol conjugate amidase Mca 10 299 1.7E-134 T 14-10-2018 IPR017811 Mycothiol S-conjugate amidase Mca GO:0010126 MB46_02095 91d8fd0b5c9324bae1c9a1b1f73f565a 300 Hamap MF_01482 Mycothiol S-conjugate amidase [mca]. 13 300 49.433 T 14-10-2018 IPR017811 Mycothiol S-conjugate amidase Mca GO:0010126 MB46_02095 91d8fd0b5c9324bae1c9a1b1f73f565a 300 SUPERFAMILY SSF102588 9 299 3.66E-69 T 14-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 MB46_02095 91d8fd0b5c9324bae1c9a1b1f73f565a 300 Gene3D G3DSA:3.40.50.10320 7 300 1.3E-75 T 14-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 MB46_02095 91d8fd0b5c9324bae1c9a1b1f73f565a 300 Pfam PF02585 GlcNAc-PI de-N-acetylase 13 160 1.5E-22 T 14-10-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 MB46_02065 c9ec79dc733770ee16403d759f18c47c 309 Pfam PF01263 Aldose 1-epimerase 17 301 2.5E-32 T 14-10-2018 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 MB46_02065 c9ec79dc733770ee16403d759f18c47c 309 Gene3D G3DSA:2.70.98.10 24 308 8.3E-64 T 14-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 MB46_02065 c9ec79dc733770ee16403d759f18c47c 309 SUPERFAMILY SSF74650 15 305 7.53E-48 T 14-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 MB46_05895 2a39ea391def8170cd8304f1633a7f21 457 Gene3D G3DSA:3.90.1150.10 106 455 4.2E-91 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MB46_05895 2a39ea391def8170cd8304f1633a7f21 457 SMART SM00345 10 67 3.6E-11 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MB46_05895 2a39ea391def8170cd8304f1633a7f21 457 Gene3D G3DSA:1.10.10.10 5 68 9.7E-14 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_05895 2a39ea391def8170cd8304f1633a7f21 457 Pfam PF00155 Aminotransferase class I and II 131 453 1.7E-21 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MB46_05895 2a39ea391def8170cd8304f1633a7f21 457 Gene3D G3DSA:3.40.640.10 138 351 4.2E-91 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MB46_05895 2a39ea391def8170cd8304f1633a7f21 457 Pfam PF00392 Bacterial regulatory proteins, gntR family 16 67 5.4E-13 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MB46_05895 2a39ea391def8170cd8304f1633a7f21 457 SUPERFAMILY SSF46785 18 76 5.53E-13 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_05895 2a39ea391def8170cd8304f1633a7f21 457 SUPERFAMILY SSF53383 61 456 1.17E-77 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MB46_01590 98b9f7a9494391ebf8104aa368bb47c7 187 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 2 187 30.296 T 14-10-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 MB46_01590 98b9f7a9494391ebf8104aa368bb47c7 187 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 1 186 5.6E-69 T 14-10-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 MB46_01590 98b9f7a9494391ebf8104aa368bb47c7 187 SUPERFAMILY SSF53328 1 185 3.66E-61 T 14-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MB46_01590 98b9f7a9494391ebf8104aa368bb47c7 187 Gene3D G3DSA:3.40.50.170 1 187 1.4E-74 T 14-10-2018 MB46_01590 98b9f7a9494391ebf8104aa368bb47c7 187 Pfam PF00551 Formyl transferase 1 181 6.7E-53 T 14-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MB46_01590 98b9f7a9494391ebf8104aa368bb47c7 187 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 133 156 - T 14-10-2018 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MB46_00805 6a06f3ca44f895c8fb2baebbe8e57cc8 238 SUPERFAMILY SSF55961 5 122 5.21E-14 T 14-10-2018 MB46_00805 6a06f3ca44f895c8fb2baebbe8e57cc8 238 Gene3D G3DSA:3.30.530.20 2 143 4.6E-11 T 14-10-2018 IPR023393 START-like domain superfamily MB46_09520 b232c99699cfea71278ee54c09731d11 530 Gene3D G3DSA:1.10.1220.110 103 159 2.4E-208 T 14-10-2018 MB46_09520 b232c99699cfea71278ee54c09731d11 530 Pfam PF05199 GMC oxidoreductase 381 520 4.6E-40 T 14-10-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 MB46_09520 b232c99699cfea71278ee54c09731d11 530 PIRSF PIRSF000137 340 530 2.6E-46 T 14-10-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 MB46_09520 b232c99699cfea71278ee54c09731d11 530 PIRSF PIRSF000137 2 330 1.2E-83 T 14-10-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 MB46_09520 b232c99699cfea71278ee54c09731d11 530 Gene3D G3DSA:4.10.450.10 45 207 2.4E-208 T 14-10-2018 IPR027424 Glucose Oxidase, domain 2 KEGG: 00260+1.2.1.8+1.1.99.1|MetaCyc: PWY-3722|MetaCyc: PWY-7494|Reactome: R-HSA-6798163 MB46_09520 b232c99699cfea71278ee54c09731d11 530 Gene3D G3DSA:3.50.50.60 12 524 2.4E-208 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_09520 b232c99699cfea71278ee54c09731d11 530 SUPERFAMILY SSF54373 304 468 5.0E-43 T 14-10-2018 MB46_09520 b232c99699cfea71278ee54c09731d11 530 Pfam PF00732 GMC oxidoreductase 12 310 3.7E-66 T 14-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 MB46_09520 b232c99699cfea71278ee54c09731d11 530 ProSitePatterns PS00624 GMC oxidoreductases signature 2. 268 282 - T 14-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 MB46_09520 b232c99699cfea71278ee54c09731d11 530 Gene3D G3DSA:3.30.410.40 160 465 2.4E-208 T 14-10-2018 MB46_09520 b232c99699cfea71278ee54c09731d11 530 SUPERFAMILY SSF51905 9 527 2.71E-70 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_06130 505e310006c4e9b707e7b13e833a471c 465 Gene3D G3DSA:3.90.1150.10 34 453 2.4E-139 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MB46_06130 505e310006c4e9b707e7b13e833a471c 465 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 263 300 - T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MB46_06130 505e310006c4e9b707e7b13e833a471c 465 Gene3D G3DSA:3.40.640.10 83 348 2.4E-139 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MB46_06130 505e310006c4e9b707e7b13e833a471c 465 Pfam PF00202 Aminotransferase class-III 49 455 1.9E-95 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MB46_06130 505e310006c4e9b707e7b13e833a471c 465 SUPERFAMILY SSF53383 37 456 1.85E-117 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MB46_19425 a153be547bcb00db0633549b6ee71d74 927 Pfam PF01345 Domain of unknown function DUF11 451 501 9.3E-10 T 14-10-2018 IPR001434 Domain of unknown function DUF11 MB46_19425 a153be547bcb00db0633549b6ee71d74 927 Gene3D G3DSA:2.60.40.10 751 863 1.0E-12 T 14-10-2018 IPR013783 Immunoglobulin-like fold MB46_19425 a153be547bcb00db0633549b6ee71d74 927 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 886 919 0.0029 T 14-10-2018 MB46_19425 a153be547bcb00db0633549b6ee71d74 927 Pfam PF00746 LPXTG cell wall anchor motif 886 920 3.1E-5 T 14-10-2018 IPR019948 Gram-positive LPXTG cell wall anchor MB46_19425 a153be547bcb00db0633549b6ee71d74 927 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 453 502 5.5E-12 T 14-10-2018 IPR001434 Domain of unknown function DUF11 MB46_19425 a153be547bcb00db0633549b6ee71d74 927 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 318 359 9.4E-4 T 14-10-2018 IPR001434 Domain of unknown function DUF11 MB46_00700 bc025b9422e793a343642ecc3d99b82b 619 Pfam PF00005 ABC transporter 391 538 2.2E-29 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_00700 bc025b9422e793a343642ecc3d99b82b 619 Pfam PF00664 ABC transporter transmembrane region 52 326 9.5E-42 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 MB46_00700 bc025b9422e793a343642ecc3d99b82b 619 SUPERFAMILY SSF52540 363 613 5.21E-78 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_00700 bc025b9422e793a343642ecc3d99b82b 619 Gene3D G3DSA:3.40.50.300 369 617 1.2E-80 T 14-10-2018 MB46_00700 bc025b9422e793a343642ecc3d99b82b 619 SUPERFAMILY SSF90123 39 359 4.45E-71 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MB46_00700 bc025b9422e793a343642ecc3d99b82b 619 SMART SM00382 398 590 4.4E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_00700 bc025b9422e793a343642ecc3d99b82b 619 Gene3D G3DSA:1.20.1560.10 17 358 4.4E-74 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MB46_00700 bc025b9422e793a343642ecc3d99b82b 619 ProSitePatterns PS00211 ABC transporters family signature. 510 524 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_13385 29428c889e432f9b766be1cbc9ae3dab 122 SMART SM01374 1 122 1.3E-83 T 14-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 MB46_13385 29428c889e432f9b766be1cbc9ae3dab 122 SUPERFAMILY SSF50193 2 122 7.59E-49 T 14-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 MB46_13385 29428c889e432f9b766be1cbc9ae3dab 122 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 122 2.0E-56 T 14-10-2018 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 MB46_13385 29428c889e432f9b766be1cbc9ae3dab 122 Gene3D G3DSA:2.40.150.20 1 122 7.1E-52 T 14-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 MB46_13385 29428c889e432f9b766be1cbc9ae3dab 122 Pfam PF00238 Ribosomal protein L14p/L23e 2 122 1.3E-52 T 14-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 MB46_13385 29428c889e432f9b766be1cbc9ae3dab 122 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 14-10-2018 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MB46_13385 29428c889e432f9b766be1cbc9ae3dab 122 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 122 25.227 T 14-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 MB46_08370 2a0199f08811a2c9a9d1f6660901f326 197 SMART SM00422 42 114 3.8E-20 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MB46_08370 2a0199f08811a2c9a9d1f6660901f326 197 Gene3D G3DSA:1.10.1660.10 42 121 4.8E-14 T 14-10-2018 MB46_08370 2a0199f08811a2c9a9d1f6660901f326 197 SUPERFAMILY SSF46955 45 130 2.15E-15 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily MB46_08370 2a0199f08811a2c9a9d1f6660901f326 197 Pfam PF13411 MerR HTH family regulatory protein 46 112 1.2E-14 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MB46_13315 c09fa58f19c5d5b038f848942af93b19 301 Gene3D G3DSA:1.10.3720.10 34 292 1.6E-58 T 14-10-2018 IPR035906 MetI-like superfamily MB46_13315 c09fa58f19c5d5b038f848942af93b19 301 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 111 292 1.9E-15 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_13315 c09fa58f19c5d5b038f848942af93b19 301 SUPERFAMILY SSF161098 33 300 4.95E-63 T 14-10-2018 IPR035906 MetI-like superfamily MB46_00045 f36cb71f0d622959b0f4e3ecdebd5d96 432 Pfam PF13416 Bacterial extracellular solute-binding protein 72 369 6.1E-42 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein MB46_00045 f36cb71f0d622959b0f4e3ecdebd5d96 432 Gene3D G3DSA:3.40.190.10 163 417 1.5E-96 T 14-10-2018 MB46_00045 f36cb71f0d622959b0f4e3ecdebd5d96 432 PRINTS PR00181 Maltose binding protein signature 332 353 4.0E-7 T 14-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 MB46_00045 f36cb71f0d622959b0f4e3ecdebd5d96 432 PRINTS PR00181 Maltose binding protein signature 389 408 4.0E-7 T 14-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 MB46_00045 f36cb71f0d622959b0f4e3ecdebd5d96 432 PRINTS PR00181 Maltose binding protein signature 154 173 4.0E-7 T 14-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 MB46_00045 f36cb71f0d622959b0f4e3ecdebd5d96 432 PRINTS PR00181 Maltose binding protein signature 175 194 4.0E-7 T 14-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 MB46_00045 f36cb71f0d622959b0f4e3ecdebd5d96 432 PRINTS PR00181 Maltose binding protein signature 95 113 4.0E-7 T 14-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 MB46_00045 f36cb71f0d622959b0f4e3ecdebd5d96 432 SUPERFAMILY SSF53850 51 426 5.69E-64 T 14-10-2018 MB46_00045 f36cb71f0d622959b0f4e3ecdebd5d96 432 Gene3D G3DSA:3.40.190.10 68 389 1.5E-96 T 14-10-2018 MB46_10135 9bf880f6893cc4dfeb70607161f5708a 230 SUPERFAMILY SSF46785 2 70 2.87E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_10135 9bf880f6893cc4dfeb70607161f5708a 230 SMART SM00345 7 66 1.3E-17 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MB46_10135 9bf880f6893cc4dfeb70607161f5708a 230 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 26 40 7.8E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MB46_10135 9bf880f6893cc4dfeb70607161f5708a 230 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 56 7.8E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MB46_10135 9bf880f6893cc4dfeb70607161f5708a 230 SUPERFAMILY SSF48008 88 220 1.54E-28 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MB46_10135 9bf880f6893cc4dfeb70607161f5708a 230 Pfam PF00392 Bacterial regulatory proteins, gntR family 5 66 1.0E-18 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MB46_10135 9bf880f6893cc4dfeb70607161f5708a 230 SMART SM00895 92 214 2.2E-24 T 14-10-2018 IPR011711 GntR, C-terminal MB46_10135 9bf880f6893cc4dfeb70607161f5708a 230 Gene3D G3DSA:1.10.10.10 1 70 3.2E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_10135 9bf880f6893cc4dfeb70607161f5708a 230 Gene3D G3DSA:1.20.120.530 88 223 1.3E-30 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MB46_10135 9bf880f6893cc4dfeb70607161f5708a 230 Pfam PF07729 FCD domain 92 213 2.1E-26 T 14-10-2018 IPR011711 GntR, C-terminal MB46_07605 56ce27e82f57b5897d39709b0a69187f 200 SUPERFAMILY SSF52172 13 196 2.7E-55 T 14-10-2018 IPR011006 CheY-like superfamily MB46_07605 56ce27e82f57b5897d39709b0a69187f 200 PIRSF PIRSF036382 3 200 4.1E-71 T 14-10-2018 IPR008327 Signal transduction response regulator, antiterminator MB46_07605 56ce27e82f57b5897d39709b0a69187f 200 SMART SM00448 14 125 2.9E-35 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MB46_07605 56ce27e82f57b5897d39709b0a69187f 200 Gene3D G3DSA:3.40.50.2300 2 142 9.1E-38 T 14-10-2018 MB46_07605 56ce27e82f57b5897d39709b0a69187f 200 SMART SM01012 141 196 2.2E-23 T 14-10-2018 IPR005561 ANTAR domain GO:0003723 MB46_07605 56ce27e82f57b5897d39709b0a69187f 200 Pfam PF03861 ANTAR domain 144 196 1.8E-19 T 14-10-2018 IPR005561 ANTAR domain GO:0003723 MB46_07605 56ce27e82f57b5897d39709b0a69187f 200 Gene3D G3DSA:1.10.10.10 143 200 1.7E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_07605 56ce27e82f57b5897d39709b0a69187f 200 Pfam PF00072 Response regulator receiver domain 16 125 4.3E-28 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MB46_14110 1671e890a0c24ce0a8ac87a7b7e5c8ec 596 Pfam PF01345 Domain of unknown function DUF11 383 486 4.4E-9 T 14-10-2018 IPR001434 Domain of unknown function DUF11 MB46_14110 1671e890a0c24ce0a8ac87a7b7e5c8ec 596 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 562 593 0.0027 T 14-10-2018 MB46_14110 1671e890a0c24ce0a8ac87a7b7e5c8ec 596 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 390 434 2.7E-6 T 14-10-2018 IPR001434 Domain of unknown function DUF11 MB46_14110 1671e890a0c24ce0a8ac87a7b7e5c8ec 596 SUPERFAMILY SSF53300 39 254 1.29E-17 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily MB46_14110 1671e890a0c24ce0a8ac87a7b7e5c8ec 596 Gene3D G3DSA:3.40.50.410 40 259 4.9E-21 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily MB46_14110 1671e890a0c24ce0a8ac87a7b7e5c8ec 596 Pfam PF00092 von Willebrand factor type A domain 50 236 4.4E-9 T 14-10-2018 IPR002035 von Willebrand factor, type A MB46_14110 1671e890a0c24ce0a8ac87a7b7e5c8ec 596 SMART SM00327 48 254 3.7E-8 T 14-10-2018 IPR002035 von Willebrand factor, type A MB46_04095 46e8707c66836cd99b7d9f344afa9529 294 PIRSF PIRSF028756 18 292 1.0E-120 T 14-10-2018 IPR016898 Polyphosphate kinase 2 KEGG: 00190+2.7.4.1 MB46_04095 46e8707c66836cd99b7d9f344afa9529 294 Gene3D G3DSA:3.40.50.300 10 290 6.3E-103 T 14-10-2018 MB46_04095 46e8707c66836cd99b7d9f344afa9529 294 SUPERFAMILY SSF52540 75 260 3.06E-28 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_04095 46e8707c66836cd99b7d9f344afa9529 294 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 44 270 1.1E-103 T 14-10-2018 IPR022488 Polyphosphate kinase-2-related MB46_04095 46e8707c66836cd99b7d9f344afa9529 294 TIGRFAM TIGR03707 PPK2_P_aer: polyphosphate kinase 2 44 271 3.4E-115 T 14-10-2018 IPR022486 Polyphosphate kinase 2, PA0141 GO:0006793|GO:0008976 KEGG: 00190+2.7.4.1 MB46_08645 fb33d5b2eea9fca754cd72e1c635afdf 770 SMART SM00954 279 389 2.7E-66 T 14-10-2018 IPR007685 RelA/SpoT GO:0015969 MB46_08645 fb33d5b2eea9fca754cd72e1c635afdf 770 Gene3D G3DSA:3.30.70.260 687 769 1.3E-14 T 14-10-2018 MB46_08645 fb33d5b2eea9fca754cd72e1c635afdf 770 SMART SM00471 87 197 1.3E-10 T 14-10-2018 IPR003607 HD/PDEase domain MB46_08645 fb33d5b2eea9fca754cd72e1c635afdf 770 SUPERFAMILY SSF81271 418 491 8.94E-21 T 14-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 MB46_08645 fb33d5b2eea9fca754cd72e1c635afdf 770 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 72 762 2.2E-244 T 14-10-2018 IPR004811 RelA/SpoT family GO:0015969 MB46_08645 fb33d5b2eea9fca754cd72e1c635afdf 770 Gene3D G3DSA:3.10.20.30 425 496 2.4E-29 T 14-10-2018 IPR012675 Beta-grasp domain superfamily MB46_08645 fb33d5b2eea9fca754cd72e1c635afdf 770 Pfam PF13328 HD domain 72 219 4.3E-45 T 14-10-2018 IPR003607 HD/PDEase domain MB46_08645 fb33d5b2eea9fca754cd72e1c635afdf 770 SUPERFAMILY SSF81301 224 435 3.43E-66 T 14-10-2018 MB46_08645 fb33d5b2eea9fca754cd72e1c635afdf 770 SUPERFAMILY SSF109604 49 234 3.45E-67 T 14-10-2018 MB46_08645 fb33d5b2eea9fca754cd72e1c635afdf 770 Pfam PF04607 Region found in RelA / SpoT proteins 279 389 2.0E-36 T 14-10-2018 IPR007685 RelA/SpoT GO:0015969 MB46_08645 fb33d5b2eea9fca754cd72e1c635afdf 770 Gene3D G3DSA:3.30.460.10 237 368 1.5E-46 T 14-10-2018 MB46_08645 fb33d5b2eea9fca754cd72e1c635afdf 770 Gene3D G3DSA:1.10.3210.10 47 234 3.5E-73 T 14-10-2018 MB46_08645 fb33d5b2eea9fca754cd72e1c635afdf 770 Pfam PF02824 TGS domain 431 490 8.7E-23 T 14-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 MB46_08645 fb33d5b2eea9fca754cd72e1c635afdf 770 Pfam PF13291 ACT domain 686 762 7.9E-15 T 14-10-2018 IPR002912 ACT domain MB46_08645 fb33d5b2eea9fca754cd72e1c635afdf 770 SUPERFAMILY SSF55021 685 764 3.71E-13 T 14-10-2018 MB46_07790 2a863b310e5b095563623b496a347a43 306 SMART SM00450 163 291 1.3E-20 T 14-10-2018 IPR001763 Rhodanese-like domain MB46_07790 2a863b310e5b095563623b496a347a43 306 SMART SM00450 21 140 3.4E-18 T 14-10-2018 IPR001763 Rhodanese-like domain MB46_07790 2a863b310e5b095563623b496a347a43 306 ProSitePatterns PS00683 Rhodanese C-terminal signature. 275 285 - T 14-10-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350|MetaCyc: PWY-7927|Reactome: R-HSA-1614558 MB46_07790 2a863b310e5b095563623b496a347a43 306 SUPERFAMILY SSF52821 14 154 1.83E-35 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily MB46_07790 2a863b310e5b095563623b496a347a43 306 Gene3D G3DSA:3.40.250.10 162 306 2.1E-39 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily MB46_07790 2a863b310e5b095563623b496a347a43 306 SUPERFAMILY SSF52821 168 295 1.2E-30 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily MB46_07790 2a863b310e5b095563623b496a347a43 306 Pfam PF00581 Rhodanese-like domain 22 136 7.1E-15 T 14-10-2018 IPR001763 Rhodanese-like domain MB46_07790 2a863b310e5b095563623b496a347a43 306 Pfam PF00581 Rhodanese-like domain 170 287 6.6E-17 T 14-10-2018 IPR001763 Rhodanese-like domain MB46_07790 2a863b310e5b095563623b496a347a43 306 Gene3D G3DSA:3.40.250.10 3 161 1.3E-41 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily MB46_07790 2a863b310e5b095563623b496a347a43 306 ProSitePatterns PS00380 Rhodanese signature 1. 52 63 - T 14-10-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350|MetaCyc: PWY-7927|Reactome: R-HSA-1614558 MB46_16790 a9c38731f24400d9921271f4bbce9d39 387 Pfam PF02803 Thiolase, C-terminal domain 260 380 1.4E-38 T 14-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 MB46_16790 a9c38731f24400d9921271f4bbce9d39 387 SUPERFAMILY SSF53901 260 380 1.35E-37 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 MB46_16790 a9c38731f24400d9921271f4bbce9d39 387 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 380 1.2E-130 T 14-10-2018 IPR002155 Thiolase GO:0016747 MB46_16790 a9c38731f24400d9921271f4bbce9d39 387 Gene3D G3DSA:3.40.47.10 6 265 8.8E-137 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 MB46_16790 a9c38731f24400d9921271f4bbce9d39 387 SUPERFAMILY SSF53901 3 259 2.66E-72 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 MB46_16790 a9c38731f24400d9921271f4bbce9d39 387 Pfam PF00108 Thiolase, N-terminal domain 5 251 4.2E-70 T 14-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 MB46_16790 a9c38731f24400d9921271f4bbce9d39 387 Gene3D G3DSA:3.40.47.10 127 378 8.8E-137 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 MB46_16790 a9c38731f24400d9921271f4bbce9d39 387 ProSitePatterns PS00737 Thiolases signature 2. 328 344 - T 14-10-2018 IPR020613 Thiolase, conserved site GO:0016747 MB46_16790 a9c38731f24400d9921271f4bbce9d39 387 PIRSF PIRSF000429 1 383 7.1E-121 T 14-10-2018 IPR002155 Thiolase GO:0016747 MB46_17740 8381adfb35036fcfcbee7d34ed7e98bf 270 TIGRFAM TIGR01490 HAD-SF-IB-hyp1: HAD hydrolase, family IB 22 222 4.9E-52 T 14-10-2018 IPR006385 HAD-superfamily hydrolase, subfamily IB, SerB1-like MB46_17740 8381adfb35036fcfcbee7d34ed7e98bf 270 Pfam PF12710 haloacid dehalogenase-like hydrolase 23 208 2.6E-24 T 14-10-2018 MB46_17740 8381adfb35036fcfcbee7d34ed7e98bf 270 Gene3D G3DSA:1.20.1440.100 34 109 5.1E-57 T 14-10-2018 MB46_17740 8381adfb35036fcfcbee7d34ed7e98bf 270 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 22 210 7.0E-16 T 14-10-2018 MB46_17740 8381adfb35036fcfcbee7d34ed7e98bf 270 SUPERFAMILY SSF56784 22 239 1.03E-27 T 14-10-2018 IPR036412 HAD-like superfamily MB46_17740 8381adfb35036fcfcbee7d34ed7e98bf 270 Gene3D G3DSA:3.40.50.1000 23 234 5.1E-57 T 14-10-2018 IPR023214 HAD superfamily MB46_03925 0b0c17c83346ebff18c52b1398c86518 541 Pfam PF04055 Radical SAM superfamily 192 363 9.4E-29 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MB46_03925 0b0c17c83346ebff18c52b1398c86518 541 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 32 483 5.7E-139 T 14-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 MB46_03925 0b0c17c83346ebff18c52b1398c86518 541 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 192 212 - T 14-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 MB46_03925 0b0c17c83346ebff18c52b1398c86518 541 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 31 487 64.002 T 14-10-2018 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 MB46_03925 0b0c17c83346ebff18c52b1398c86518 541 SMART SM00729 188 406 5.4E-56 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 MB46_03925 0b0c17c83346ebff18c52b1398c86518 541 Gene3D G3DSA:3.80.30.20 187 420 2.7E-86 T 14-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe MB46_03925 0b0c17c83346ebff18c52b1398c86518 541 Gene3D G3DSA:3.40.50.12160 32 175 9.1E-30 T 14-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily MB46_03925 0b0c17c83346ebff18c52b1398c86518 541 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 33 482 1.5E-132 T 14-10-2018 MB46_03925 0b0c17c83346ebff18c52b1398c86518 541 SUPERFAMILY SSF102114 175 409 1.44E-54 T 14-10-2018 MB46_03925 0b0c17c83346ebff18c52b1398c86518 541 Pfam PF00919 Uncharacterized protein family UPF0004 33 145 2.6E-21 T 14-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 MB46_10915 db12838c337d49d27f12f44f2bf704a6 279 SUPERFAMILY SSF55821 6 215 2.41E-49 T 14-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily MB46_10915 db12838c337d49d27f12f44f2bf704a6 279 Pfam PF01300 Telomere recombination 24 202 2.6E-41 T 14-10-2018 IPR006070 YrdC-like domain GO:0003725 MB46_10915 db12838c337d49d27f12f44f2bf704a6 279 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 12 212 4.5E-49 T 14-10-2018 IPR006070 YrdC-like domain GO:0003725 MB46_10915 db12838c337d49d27f12f44f2bf704a6 279 Gene3D G3DSA:3.90.870.10 3 217 1.2E-60 T 14-10-2018 MB46_10105 42737261f819fdc212def81fd7162b8a 429 SUPERFAMILY SSF55874 301 426 7.98E-12 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MB46_10105 42737261f819fdc212def81fd7162b8a 429 Pfam PF07730 Histidine kinase 195 260 5.9E-18 T 14-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 MB46_07100 0cfa403d35c42d247b4ba6d74916691a 630 Pfam PF01494 FAD binding domain 32 405 1.1E-72 T 14-10-2018 IPR002938 FAD-binding domain GO:0071949 MB46_07100 0cfa403d35c42d247b4ba6d74916691a 630 SUPERFAMILY SSF54373 222 322 4.71E-30 T 14-10-2018 MB46_07100 0cfa403d35c42d247b4ba6d74916691a 630 SUPERFAMILY SSF52833 445 624 4.47E-46 T 14-10-2018 IPR036249 Thioredoxin-like superfamily MB46_07100 0cfa403d35c42d247b4ba6d74916691a 630 SUPERFAMILY SSF51905 33 417 7.86E-46 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_07100 0cfa403d35c42d247b4ba6d74916691a 630 Gene3D G3DSA:3.30.9.50 102 319 2.5E-122 T 14-10-2018 MB46_07100 0cfa403d35c42d247b4ba6d74916691a 630 Gene3D G3DSA:3.40.30.20 421 625 3.8E-51 T 14-10-2018 IPR038220 Phenol hydroxylase, C-terminal TRX-fold domain superfamily MB46_07100 0cfa403d35c42d247b4ba6d74916691a 630 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 390 406 2.1E-33 T 14-10-2018 MB46_07100 0cfa403d35c42d247b4ba6d74916691a 630 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 198 213 2.1E-33 T 14-10-2018 MB46_07100 0cfa403d35c42d247b4ba6d74916691a 630 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 34 56 2.1E-33 T 14-10-2018 MB46_07100 0cfa403d35c42d247b4ba6d74916691a 630 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 339 354 2.1E-33 T 14-10-2018 MB46_07100 0cfa403d35c42d247b4ba6d74916691a 630 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 354 370 2.1E-33 T 14-10-2018 MB46_07100 0cfa403d35c42d247b4ba6d74916691a 630 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 372 390 2.1E-33 T 14-10-2018 MB46_07100 0cfa403d35c42d247b4ba6d74916691a 630 Pfam PF07976 Phenol hydroxylase, C-terminal dimerisation domain 435 593 1.5E-36 T 14-10-2018 IPR012941 Phenol hydroxylase, C-terminal dimerisation domain MB46_07100 0cfa403d35c42d247b4ba6d74916691a 630 Gene3D G3DSA:3.50.50.60 34 402 2.5E-122 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_15410 d5e0230ca8338bcc376fa0550d2228a2 829 Gene3D G3DSA:3.40.50.300 495 718 8.1E-87 T 14-10-2018 MB46_15410 d5e0230ca8338bcc376fa0550d2228a2 829 SUPERFAMILY SSF52540 168 435 2.21E-75 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_15410 d5e0230ca8338bcc376fa0550d2228a2 829 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 210 339 5.3E-13 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MB46_15410 d5e0230ca8338bcc376fa0550d2228a2 829 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 720 800 3.1E-27 T 14-10-2018 IPR019489 Clp ATPase, C-terminal MB46_15410 d5e0230ca8338bcc376fa0550d2228a2 829 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 16 68 2.1E-17 T 14-10-2018 IPR004176 Clp, N-terminal MB46_15410 d5e0230ca8338bcc376fa0550d2228a2 829 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 93 142 1.2E-16 T 14-10-2018 IPR004176 Clp, N-terminal MB46_15410 d5e0230ca8338bcc376fa0550d2228a2 829 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 300 312 - T 14-10-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 MB46_15410 d5e0230ca8338bcc376fa0550d2228a2 829 Pfam PF02151 UvrB/uvrC motif 424 454 1.1E-5 T 14-10-2018 IPR001943 UVR domain GO:0005515 MB46_15410 d5e0230ca8338bcc376fa0550d2228a2 829 Gene3D G3DSA:4.10.860.10 414 472 8.0E-43 T 14-10-2018 MB46_15410 d5e0230ca8338bcc376fa0550d2228a2 829 SUPERFAMILY SSF52540 491 803 2.3E-80 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_15410 d5e0230ca8338bcc376fa0550d2228a2 829 Gene3D G3DSA:1.10.1780.10 1 148 9.7E-63 T 14-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 MB46_15410 d5e0230ca8338bcc376fa0550d2228a2 829 Gene3D G3DSA:1.10.8.60 720 824 1.8E-32 T 14-10-2018 MB46_15410 d5e0230ca8338bcc376fa0550d2228a2 829 SMART SM01086 720 813 3.2E-40 T 14-10-2018 IPR019489 Clp ATPase, C-terminal MB46_15410 d5e0230ca8338bcc376fa0550d2228a2 829 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 620 638 3.3E-40 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 MB46_15410 d5e0230ca8338bcc376fa0550d2228a2 829 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 653 667 3.3E-40 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 MB46_15410 d5e0230ca8338bcc376fa0550d2228a2 829 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 546 564 3.3E-40 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 MB46_15410 d5e0230ca8338bcc376fa0550d2228a2 829 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 591 609 3.3E-40 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 MB46_15410 d5e0230ca8338bcc376fa0550d2228a2 829 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 576 594 - T 14-10-2018 IPR028299 ClpA/B, conserved site 2 MB46_15410 d5e0230ca8338bcc376fa0550d2228a2 829 Gene3D G3DSA:3.40.50.300 159 348 9.0E-72 T 14-10-2018 MB46_15410 d5e0230ca8338bcc376fa0550d2228a2 829 Gene3D G3DSA:1.10.8.60 352 486 8.0E-43 T 14-10-2018 MB46_15410 d5e0230ca8338bcc376fa0550d2228a2 829 SMART SM00382 205 349 6.8E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_15410 d5e0230ca8338bcc376fa0550d2228a2 829 SMART SM00382 542 692 6.1E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_15410 d5e0230ca8338bcc376fa0550d2228a2 829 Pfam PF07724 AAA domain (Cdc48 subfamily) 542 713 6.5E-54 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MB46_15410 d5e0230ca8338bcc376fa0550d2228a2 829 SUPERFAMILY SSF81923 3 143 4.91E-32 T 14-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 MB46_14665 aee110635a75d87c9b89726f8133f478 154 PIRSF PIRSF000303 3 154 1.3E-52 T 14-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 MB46_14665 aee110635a75d87c9b89726f8133f478 154 Pfam PF00255 Glutathione peroxidase 7 107 3.2E-36 T 14-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 MB46_14665 aee110635a75d87c9b89726f8133f478 154 Gene3D G3DSA:3.40.30.10 3 154 4.9E-53 T 14-10-2018 MB46_14665 aee110635a75d87c9b89726f8133f478 154 SUPERFAMILY SSF52833 9 153 3.44E-47 T 14-10-2018 IPR036249 Thioredoxin-like superfamily MB46_14665 aee110635a75d87c9b89726f8133f478 154 PRINTS PR01011 Glutathione peroxidase family signature 54 70 1.5E-17 T 14-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 MB46_14665 aee110635a75d87c9b89726f8133f478 154 PRINTS PR01011 Glutathione peroxidase family signature 115 124 1.5E-17 T 14-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 MB46_14665 aee110635a75d87c9b89726f8133f478 154 PRINTS PR01011 Glutathione peroxidase family signature 19 36 1.5E-17 T 14-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 MB46_14665 aee110635a75d87c9b89726f8133f478 154 ProSitePatterns PS00460 Glutathione peroxidases active site. 21 36 - T 14-10-2018 IPR029759 Glutathione peroxidase active site Reactome: R-HSA-3299685 MB46_09265 a05cf2bd68211edb3c17f0b77296e0fb 361 PIRSF PIRSF001619 1 327 3.8E-107 T 14-10-2018 IPR024177 Biotin synthase KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 MB46_09265 a05cf2bd68211edb3c17f0b77296e0fb 361 SUPERFAMILY SSF102114 17 322 2.88E-72 T 14-10-2018 MB46_09265 a05cf2bd68211edb3c17f0b77296e0fb 361 Pfam PF04055 Radical SAM superfamily 66 221 1.0E-13 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MB46_09265 a05cf2bd68211edb3c17f0b77296e0fb 361 SMART SM00729 56 262 2.0E-32 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 MB46_09265 a05cf2bd68211edb3c17f0b77296e0fb 361 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 233 321 8.5E-13 T 14-10-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 MB46_09265 a05cf2bd68211edb3c17f0b77296e0fb 361 TIGRFAM TIGR00433 bioB: biotin synthase 29 321 5.8E-112 T 14-10-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 MB46_09265 a05cf2bd68211edb3c17f0b77296e0fb 361 SMART SM00876 233 323 5.8E-30 T 14-10-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 MB46_09265 a05cf2bd68211edb3c17f0b77296e0fb 361 Hamap MF_01694 Biotin synthase [bioB]. 16 324 38.093 T 14-10-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 MB46_09265 a05cf2bd68211edb3c17f0b77296e0fb 361 Gene3D G3DSA:3.20.20.70 19 324 8.9E-102 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MB46_04615 c29724acbab2cb0d2d0e20c184c21216 377 Pfam PF00226 DnaJ domain 3 64 5.9E-26 T 14-10-2018 IPR001623 DnaJ domain MB46_04615 c29724acbab2cb0d2d0e20c184c21216 377 Gene3D G3DSA:2.60.260.20 255 359 3.1E-24 T 14-10-2018 MB46_04615 c29724acbab2cb0d2d0e20c184c21216 377 Gene3D G3DSA:2.60.260.20 113 249 3.6E-30 T 14-10-2018 MB46_04615 c29724acbab2cb0d2d0e20c184c21216 377 SUPERFAMILY SSF57938 130 211 7.06E-17 T 14-10-2018 IPR036410 Heat shock protein DnaJ, cysteine-rich domain superfamily MB46_04615 c29724acbab2cb0d2d0e20c184c21216 377 PRINTS PR00625 DnaJ domain signature 59 78 3.9E-25 T 14-10-2018 IPR001623 DnaJ domain MB46_04615 c29724acbab2cb0d2d0e20c184c21216 377 PRINTS PR00625 DnaJ domain signature 39 59 3.9E-25 T 14-10-2018 IPR001623 DnaJ domain MB46_04615 c29724acbab2cb0d2d0e20c184c21216 377 PRINTS PR00625 DnaJ domain signature 5 23 3.9E-25 T 14-10-2018 IPR001623 DnaJ domain MB46_04615 c29724acbab2cb0d2d0e20c184c21216 377 PRINTS PR00625 DnaJ domain signature 23 38 3.9E-25 T 14-10-2018 IPR001623 DnaJ domain MB46_04615 c29724acbab2cb0d2d0e20c184c21216 377 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 1 373 35.452 T 14-10-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 MB46_04615 c29724acbab2cb0d2d0e20c184c21216 377 SMART SM00271 2 59 2.3E-27 T 14-10-2018 IPR001623 DnaJ domain MB46_04615 c29724acbab2cb0d2d0e20c184c21216 377 SUPERFAMILY SSF49493 115 253 5.76E-16 T 14-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 MB46_04615 c29724acbab2cb0d2d0e20c184c21216 377 Pfam PF00684 DnaJ central domain 143 207 4.5E-10 T 14-10-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 MB46_04615 c29724acbab2cb0d2d0e20c184c21216 377 ProSitePatterns PS00636 Nt-dnaJ domain signature. 44 63 - T 14-10-2018 IPR018253 DnaJ domain, conserved site MB46_04615 c29724acbab2cb0d2d0e20c184c21216 377 Pfam PF01556 DnaJ C terminal domain 118 333 1.2E-33 T 14-10-2018 IPR002939 Chaperone DnaJ, C-terminal MB46_04615 c29724acbab2cb0d2d0e20c184c21216 377 Gene3D G3DSA:1.10.287.110 2 108 2.0E-35 T 14-10-2018 IPR036869 Chaperone J-domain superfamily MB46_04615 c29724acbab2cb0d2d0e20c184c21216 377 Gene3D G3DSA:2.10.230.10 143 207 3.6E-30 T 14-10-2018 MB46_04615 c29724acbab2cb0d2d0e20c184c21216 377 SUPERFAMILY SSF46565 3 103 6.41E-32 T 14-10-2018 IPR036869 Chaperone J-domain superfamily MB46_04615 c29724acbab2cb0d2d0e20c184c21216 377 SUPERFAMILY SSF49493 259 344 9.94E-18 T 14-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 MB46_02890 f0396274853bec8344b3d6b6051af16b 298 Gene3D G3DSA:3.30.930.10 1 223 2.1E-55 T 14-10-2018 MB46_02890 f0396274853bec8344b3d6b6051af16b 298 SUPERFAMILY SSF55681 13 217 6.36E-38 T 14-10-2018 MB46_02890 f0396274853bec8344b3d6b6051af16b 298 Pfam PF03099 Biotin/lipoate A/B protein ligase family 40 167 3.6E-12 T 14-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 MB46_02890 f0396274853bec8344b3d6b6051af16b 298 Gene3D G3DSA:2.30.30.100 239 287 1.4E-16 T 14-10-2018 MB46_02890 f0396274853bec8344b3d6b6051af16b 298 Pfam PF02237 Biotin protein ligase C terminal domain 238 285 7.8E-6 T 14-10-2018 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MB46_02890 f0396274853bec8344b3d6b6051af16b 298 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 21 285 1.4E-29 T 14-10-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MB46_06480 9c10285fce66e2f75d0204ab2e5519a6 627 Pfam PF00486 Transcriptional regulatory protein, C terminal 25 83 8.9E-9 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MB46_06480 9c10285fce66e2f75d0204ab2e5519a6 627 Pfam PF03704 Bacterial transcriptional activator domain 104 244 9.0E-30 T 14-10-2018 IPR005158 Bacterial transcriptional activator domain MB46_06480 9c10285fce66e2f75d0204ab2e5519a6 627 SUPERFAMILY SSF48452 113 254 2.42E-23 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MB46_06480 9c10285fce66e2f75d0204ab2e5519a6 627 SMART SM01043 104 245 1.0E-33 T 14-10-2018 IPR005158 Bacterial transcriptional activator domain MB46_06480 9c10285fce66e2f75d0204ab2e5519a6 627 SUPERFAMILY SSF46894 5 81 3.68E-10 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MB46_06480 9c10285fce66e2f75d0204ab2e5519a6 627 Gene3D G3DSA:1.25.40.10 102 273 6.1E-37 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MB46_06480 9c10285fce66e2f75d0204ab2e5519a6 627 SMART SM00862 18 97 7.3E-11 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MB46_06480 9c10285fce66e2f75d0204ab2e5519a6 627 Gene3D G3DSA:1.10.10.10 1 99 1.0E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_11100 f7a8c86759097ae15d055fe5c57497b0 172 SMART SM00903 18 163 1.5E-30 T 14-10-2018 IPR002563 Flavin reductase like domain GO:0010181 MB46_11100 f7a8c86759097ae15d055fe5c57497b0 172 Gene3D G3DSA:2.30.110.10 2 170 1.5E-36 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 MB46_11100 f7a8c86759097ae15d055fe5c57497b0 172 SUPERFAMILY SSF50475 13 164 1.13E-31 T 14-10-2018 MB46_11100 f7a8c86759097ae15d055fe5c57497b0 172 Pfam PF01613 Flavin reductase like domain 20 164 4.0E-30 T 14-10-2018 IPR002563 Flavin reductase like domain GO:0010181 MB46_07220 00da83351bdef9bb5ecefd4ddfd8d5b3 149 SUPERFAMILY SSF63817 3 145 3.73E-15 T 14-10-2018 IPR023365 Sortase domain superfamily MB46_07220 00da83351bdef9bb5ecefd4ddfd8d5b3 149 Pfam PF04203 Sortase family 3 143 1.5E-15 T 14-10-2018 IPR005754 Sortase family MB46_07220 00da83351bdef9bb5ecefd4ddfd8d5b3 149 Gene3D G3DSA:2.40.260.10 1 147 3.7E-25 T 14-10-2018 IPR023365 Sortase domain superfamily MB46_18185 0ab6f76b983ccd5cced7a1794a4df9a5 349 Pfam PF00296 Luciferase-like monooxygenase 14 261 1.2E-26 T 14-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MB46_18185 0ab6f76b983ccd5cced7a1794a4df9a5 349 Gene3D G3DSA:3.20.20.30 20 336 1.6E-45 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 MB46_18185 0ab6f76b983ccd5cced7a1794a4df9a5 349 SUPERFAMILY SSF51679 13 338 5.23E-51 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 MB46_07730 e08e4e8fd473e524dd2c2e7e222554b2 187 Hamap MF_00163 Peptide deformylase [def]. 2 160 28.055 T 14-10-2018 IPR023635 Peptide deformylase MB46_07730 e08e4e8fd473e524dd2c2e7e222554b2 187 PIRSF PIRSF004749 1 174 4.9E-48 T 14-10-2018 IPR023635 Peptide deformylase MB46_07730 e08e4e8fd473e524dd2c2e7e222554b2 187 PRINTS PR01576 Peptide deformylase signature 87 98 9.6E-34 T 14-10-2018 IPR023635 Peptide deformylase MB46_07730 e08e4e8fd473e524dd2c2e7e222554b2 187 PRINTS PR01576 Peptide deformylase signature 99 117 9.6E-34 T 14-10-2018 IPR023635 Peptide deformylase MB46_07730 e08e4e8fd473e524dd2c2e7e222554b2 187 PRINTS PR01576 Peptide deformylase signature 118 147 9.6E-34 T 14-10-2018 IPR023635 Peptide deformylase MB46_07730 e08e4e8fd473e524dd2c2e7e222554b2 187 PRINTS PR01576 Peptide deformylase signature 33 62 9.6E-34 T 14-10-2018 IPR023635 Peptide deformylase MB46_07730 e08e4e8fd473e524dd2c2e7e222554b2 187 Pfam PF01327 Polypeptide deformylase 5 149 3.3E-46 T 14-10-2018 IPR023635 Peptide deformylase MB46_07730 e08e4e8fd473e524dd2c2e7e222554b2 187 Gene3D G3DSA:3.90.45.10 1 179 1.0E-55 T 14-10-2018 IPR036821 Peptide deformylase superfamily MB46_07730 e08e4e8fd473e524dd2c2e7e222554b2 187 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 8 151 5.5E-41 T 14-10-2018 IPR023635 Peptide deformylase MB46_07730 e08e4e8fd473e524dd2c2e7e222554b2 187 SUPERFAMILY SSF56420 1 155 4.58E-54 T 14-10-2018 IPR036821 Peptide deformylase superfamily MB46_04365 d44d0ff9ee1cc9e12af0046c93bf7d93 379 Gene3D G3DSA:1.10.230.10 224 331 6.8E-129 T 14-10-2018 IPR016143 Citrate synthase-like, small alpha subdomain MB46_04365 d44d0ff9ee1cc9e12af0046c93bf7d93 379 ProSitePatterns PS00480 Citrate synthase signature. 267 279 - T 14-10-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 MB46_04365 d44d0ff9ee1cc9e12af0046c93bf7d93 379 PRINTS PR00143 Citrate synthase signature 127 140 4.7E-36 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 MB46_04365 d44d0ff9ee1cc9e12af0046c93bf7d93 379 PRINTS PR00143 Citrate synthase signature 198 226 4.7E-36 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 MB46_04365 d44d0ff9ee1cc9e12af0046c93bf7d93 379 PRINTS PR00143 Citrate synthase signature 176 191 4.7E-36 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 MB46_04365 d44d0ff9ee1cc9e12af0046c93bf7d93 379 PRINTS PR00143 Citrate synthase signature 337 351 4.7E-36 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 MB46_04365 d44d0ff9ee1cc9e12af0046c93bf7d93 379 PRINTS PR00143 Citrate synthase signature 260 280 4.7E-36 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 MB46_04365 d44d0ff9ee1cc9e12af0046c93bf7d93 379 PRINTS PR00143 Citrate synthase signature 317 333 4.7E-36 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 MB46_04365 d44d0ff9ee1cc9e12af0046c93bf7d93 379 Gene3D G3DSA:1.10.580.10 29 357 6.8E-129 T 14-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 MB46_04365 d44d0ff9ee1cc9e12af0046c93bf7d93 379 PIRSF PIRSF001369 2 379 2.8E-111 T 14-10-2018 IPR024176 Citrate synthase, bacterial-type MB46_04365 d44d0ff9ee1cc9e12af0046c93bf7d93 379 SUPERFAMILY SSF48256 6 377 6.02E-121 T 14-10-2018 IPR036969 Citrate synthase superfamily GO:0046912 MB46_04365 d44d0ff9ee1cc9e12af0046c93bf7d93 379 TIGRFAM TIGR01800 cit_synth_II: 2-methylcitrate synthase/citrate synthase II 8 377 3.5E-131 T 14-10-2018 IPR011278 2-methylcitrate synthase/citrate synthase type I GO:0005737|GO:0046912 MB46_04365 d44d0ff9ee1cc9e12af0046c93bf7d93 379 Pfam PF00285 Citrate synthase, C-terminal domain 9 366 6.3E-114 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 MB46_12865 a5bb8118dfd32377d5f4dc98121babe6 453 Gene3D G3DSA:1.20.1720.10 1 232 2.3E-33 T 14-10-2018 MB46_12865 a5bb8118dfd32377d5f4dc98121babe6 453 SUPERFAMILY SSF103473 2 444 4.58E-48 T 14-10-2018 IPR036259 MFS transporter superfamily MB46_12865 a5bb8118dfd32377d5f4dc98121babe6 453 Gene3D G3DSA:1.20.1250.20 248 452 3.0E-11 T 14-10-2018 MB46_12865 a5bb8118dfd32377d5f4dc98121babe6 453 Pfam PF07690 Major Facilitator Superfamily 9 401 8.2E-32 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MB46_17270 112b912b9a405a1821787d76ebc166b6 806 Gene3D G3DSA:2.40.10.10 246 348 2.2E-20 T 14-10-2018 MB46_17270 112b912b9a405a1821787d76ebc166b6 806 SUPERFAMILY SSF50494 244 457 2.7E-10 T 14-10-2018 IPR009003 Peptidase S1, PA clan MB46_17270 112b912b9a405a1821787d76ebc166b6 806 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 771 803 0.0018 T 14-10-2018 MB46_17270 112b912b9a405a1821787d76ebc166b6 806 Gene3D G3DSA:2.60.40.10 474 558 1.6E-5 T 14-10-2018 IPR013783 Immunoglobulin-like fold MB46_17270 112b912b9a405a1821787d76ebc166b6 806 Gene3D G3DSA:2.40.10.10 349 449 2.2E-20 T 14-10-2018 MB46_17270 112b912b9a405a1821787d76ebc166b6 806 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 265 270 - T 14-10-2018 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 MB46_17270 112b912b9a405a1821787d76ebc166b6 806 Gene3D G3DSA:2.60.40.10 563 641 2.4E-8 T 14-10-2018 IPR013783 Immunoglobulin-like fold MB46_16840 9afa4f12de55c4a4a3c4960565603fde 101 Hamap MF_00537 30S ribosomal protein S14 [rpsN]. 1 101 26.471 T 14-10-2018 IPR023036 Ribosomal protein S14, bacterial/plastid MB46_16840 9afa4f12de55c4a4a3c4960565603fde 101 Pfam PF00253 Ribosomal protein S14p/S29e 48 100 1.5E-24 T 14-10-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MB46_16840 9afa4f12de55c4a4a3c4960565603fde 101 Gene3D G3DSA:4.10.830.10 41 101 9.5E-23 T 14-10-2018 MB46_16840 9afa4f12de55c4a4a3c4960565603fde 101 SUPERFAMILY SSF57716 2 101 3.85E-34 T 14-10-2018 MB46_18950 0b467581fd7608a03facd71d8653f21a 327 Gene3D G3DSA:3.90.180.10 13 325 3.8E-107 T 14-10-2018 MB46_18950 0b467581fd7608a03facd71d8653f21a 327 Pfam PF00107 Zinc-binding dehydrogenase 152 268 3.2E-29 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 MB46_18950 0b467581fd7608a03facd71d8653f21a 327 SMART SM00829 10 325 3.2E-50 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MB46_18950 0b467581fd7608a03facd71d8653f21a 327 TIGRFAM TIGR02824 quinone_pig3: putative NAD(P)H quinone oxidoreductase, PIG3 family 1 326 1.4E-140 T 14-10-2018 IPR014189 Quinone oxidoreductase PIG3 Reactome: R-HSA-6803205 MB46_18950 0b467581fd7608a03facd71d8653f21a 327 SUPERFAMILY SSF51735 112 289 7.01E-52 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_18950 0b467581fd7608a03facd71d8653f21a 327 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 88 8.3E-8 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MB46_18950 0b467581fd7608a03facd71d8653f21a 327 Gene3D G3DSA:3.40.50.720 121 264 3.8E-107 T 14-10-2018 MB46_18950 0b467581fd7608a03facd71d8653f21a 327 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 141 162 - T 14-10-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 MB46_18950 0b467581fd7608a03facd71d8653f21a 327 SUPERFAMILY SSF50129 1 141 7.61E-37 T 14-10-2018 IPR011032 GroES-like superfamily MB46_20000 844c9831c11eee28865ceeb8ad0d5851 225 SUPERFAMILY SSF52218 1 199 2.55E-40 T 14-10-2018 IPR029039 Flavoprotein-like superfamily MB46_20000 844c9831c11eee28865ceeb8ad0d5851 225 Gene3D G3DSA:3.40.50.360 2 216 4.7E-43 T 14-10-2018 IPR029039 Flavoprotein-like superfamily MB46_20000 844c9831c11eee28865ceeb8ad0d5851 225 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 2 213 22.182 T 14-10-2018 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 MB46_20000 844c9831c11eee28865ceeb8ad0d5851 225 Pfam PF02525 Flavodoxin-like fold 3 202 1.3E-39 T 14-10-2018 IPR003680 Flavodoxin-like fold MB46_19200 844c9831c11eee28865ceeb8ad0d5851 225 SUPERFAMILY SSF52218 1 199 2.55E-40 T 14-10-2018 IPR029039 Flavoprotein-like superfamily MB46_19200 844c9831c11eee28865ceeb8ad0d5851 225 Gene3D G3DSA:3.40.50.360 2 216 4.7E-43 T 14-10-2018 IPR029039 Flavoprotein-like superfamily MB46_19200 844c9831c11eee28865ceeb8ad0d5851 225 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 2 213 22.182 T 14-10-2018 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 MB46_19200 844c9831c11eee28865ceeb8ad0d5851 225 Pfam PF02525 Flavodoxin-like fold 3 202 1.3E-39 T 14-10-2018 IPR003680 Flavodoxin-like fold MB46_07075 62de5b04855d54bd76ce1b5bea123fb8 497 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 286 297 - T 14-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 MB46_07075 62de5b04855d54bd76ce1b5bea123fb8 497 TIGRFAM TIGR02299 HpaE: 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase 14 497 4.5E-200 T 14-10-2018 IPR011985 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase GO:0018480|GO:1901023 MB46_07075 62de5b04855d54bd76ce1b5bea123fb8 497 SUPERFAMILY SSF53720 8 487 9.03E-163 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 MB46_07075 62de5b04855d54bd76ce1b5bea123fb8 497 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 258 265 - T 14-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 MB46_07075 62de5b04855d54bd76ce1b5bea123fb8 497 Gene3D G3DSA:3.40.309.10 263 453 1.0E-173 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 MB46_07075 62de5b04855d54bd76ce1b5bea123fb8 497 Gene3D G3DSA:3.40.605.10 18 479 1.0E-173 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 MB46_07075 62de5b04855d54bd76ce1b5bea123fb8 497 Pfam PF00171 Aldehyde dehydrogenase family 22 483 8.2E-167 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 MB46_15290 fbcc368e8e0ada136e07ac55f6e0d470 111 Gene3D G3DSA:3.40.630.30 15 107 7.3E-20 T 14-10-2018 MB46_15290 fbcc368e8e0ada136e07ac55f6e0d470 111 SUPERFAMILY SSF55729 17 102 1.14E-18 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase MB46_15290 fbcc368e8e0ada136e07ac55f6e0d470 111 Pfam PF14542 GCN5-related N-acetyl-transferase 26 102 3.1E-19 T 14-10-2018 IPR031165 Yjdj-type Gcn5-related N-acetyltransferase MB46_16525 d762dd9e3ad1438f02f8fcf728498448 403 Pfam PF00155 Aminotransferase class I and II 34 389 1.7E-50 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MB46_16525 d762dd9e3ad1438f02f8fcf728498448 403 Gene3D G3DSA:3.40.640.10 4 402 2.7E-109 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MB46_16525 d762dd9e3ad1438f02f8fcf728498448 403 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 241 254 - T 14-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 MB46_16525 d762dd9e3ad1438f02f8fcf728498448 403 SUPERFAMILY SSF53383 11 397 1.6E-88 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MB46_14445 1fcd02e4c3bae32ec4d8b414d2c1a856 153 Gene3D G3DSA:3.10.129.10 6 151 7.5E-47 T 14-10-2018 MB46_14445 1fcd02e4c3bae32ec4d8b414d2c1a856 153 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 19 133 5.5E-24 T 14-10-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 MB46_14445 1fcd02e4c3bae32ec4d8b414d2c1a856 153 Pfam PF03061 Thioesterase superfamily 48 124 3.1E-11 T 14-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 MB46_14445 1fcd02e4c3bae32ec4d8b414d2c1a856 153 TIGRFAM TIGR02286 PaaD: phenylacetic acid degradation protein PaaD 20 138 3.3E-37 T 14-10-2018 IPR011973 Phenylacetic acid degradation protein PaaD GO:0016790 MB46_14445 1fcd02e4c3bae32ec4d8b414d2c1a856 153 SUPERFAMILY SSF54637 11 140 6.58E-29 T 14-10-2018 IPR029069 HotDog domain superfamily MB46_01020 25e05dc7978e139e52f04486050089d7 316 Gene3D G3DSA:3.40.960.10 200 304 5.6E-13 T 14-10-2018 MB46_01020 25e05dc7978e139e52f04486050089d7 316 SUPERFAMILY SSF52980 199 307 8.04E-8 T 14-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 MB46_01020 25e05dc7978e139e52f04486050089d7 316 Pfam PF04480 Protein of unknown function (DUF559) 241 299 9.7E-6 T 14-10-2018 IPR007569 Protein of unknown function DUF559 MB46_03510 922f99dea1e9b944868f3c0b436fe9a3 296 Pfam PF01148 Cytidylyltransferase family 24 292 1.7E-53 T 14-10-2018 MB46_03510 922f99dea1e9b944868f3c0b436fe9a3 296 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 251 277 - T 14-10-2018 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7817 MB46_09555 e3fa4d3c77a3bc778a2f1a05237f7f33 226 ProSitePatterns PS00761 Signal peptidases I signature 3. 151 164 - T 14-10-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 MB46_09555 e3fa4d3c77a3bc778a2f1a05237f7f33 226 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 146 165 3.7E-22 T 14-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 MB46_09555 e3fa4d3c77a3bc778a2f1a05237f7f33 226 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 98 110 3.7E-22 T 14-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 MB46_09555 e3fa4d3c77a3bc778a2f1a05237f7f33 226 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 18 34 3.7E-22 T 14-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 MB46_09555 e3fa4d3c77a3bc778a2f1a05237f7f33 226 SUPERFAMILY SSF51306 17 198 6.8E-50 T 14-10-2018 IPR036286 LexA/Signal peptidase-like superfamily MB46_09555 e3fa4d3c77a3bc778a2f1a05237f7f33 226 Pfam PF00717 Peptidase S24-like 24 66 1.5E-8 T 14-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C MB46_09555 e3fa4d3c77a3bc778a2f1a05237f7f33 226 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 2 192 3.0E-42 T 14-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 MB46_09555 e3fa4d3c77a3bc778a2f1a05237f7f33 226 Pfam PF10502 Signal peptidase, peptidase S26 87 186 1.2E-9 T 14-10-2018 IPR019533 Peptidase S26 MB46_17340 2c0f57d2d2401ee2c41be47cdea5f84d 152 SUPERFAMILY SSF52304 11 150 2.35E-59 T 14-10-2018 IPR036441 Dehydroquinase, class II superfamily GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MB46_17340 2c0f57d2d2401ee2c41be47cdea5f84d 152 PIRSF PIRSF001399 8 152 1.1E-59 T 14-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MB46_17340 2c0f57d2d2401ee2c41be47cdea5f84d 152 Pfam PF01220 Dehydroquinase class II 12 147 1.8E-61 T 14-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MB46_17340 2c0f57d2d2401ee2c41be47cdea5f84d 152 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 25 147 1.0E-44 T 14-10-2018 MB46_17340 2c0f57d2d2401ee2c41be47cdea5f84d 152 TIGRFAM TIGR01088 aroQ: 3-dehydroquinate dehydratase, type II 12 149 4.6E-60 T 14-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MB46_17340 2c0f57d2d2401ee2c41be47cdea5f84d 152 Gene3D G3DSA:3.40.50.9100 5 152 8.9E-65 T 14-10-2018 IPR036441 Dehydroquinase, class II superfamily GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MB46_17340 2c0f57d2d2401ee2c41be47cdea5f84d 152 Hamap MF_00169 3-dehydroquinate dehydratase [aroQ]. 1 152 69.55 T 14-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MB46_17340 2c0f57d2d2401ee2c41be47cdea5f84d 152 ProSitePatterns PS01029 Dehydroquinase class II signature. 15 32 - T 14-10-2018 IPR018509 Dehydroquinase, class II, conserved site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MB46_07815 a7e40f1e2494f967982d71c941523f53 146 Pfam PF01641 SelR domain 23 142 1.4E-50 T 14-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 MB46_07815 a7e40f1e2494f967982d71c941523f53 146 SUPERFAMILY SSF51316 18 144 2.14E-53 T 14-10-2018 IPR011057 Mss4-like superfamily MB46_07815 a7e40f1e2494f967982d71c941523f53 146 Gene3D G3DSA:2.170.150.20 1 145 2.0E-55 T 14-10-2018 MB46_07815 a7e40f1e2494f967982d71c941523f53 146 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 19 141 6.4E-47 T 14-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 MB46_02470 913e8a9b20adf476fead87fe48a70c4a 880 SMART SM00421 826 880 1.5E-10 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_02470 913e8a9b20adf476fead87fe48a70c4a 880 SUPERFAMILY SSF52540 13 212 3.49E-12 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_02470 913e8a9b20adf476fead87fe48a70c4a 880 Pfam PF00196 Bacterial regulatory proteins, luxR family 829 880 1.1E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_02470 913e8a9b20adf476fead87fe48a70c4a 880 Gene3D G3DSA:3.40.50.300 5 163 5.0E-6 T 14-10-2018 MB46_02470 913e8a9b20adf476fead87fe48a70c4a 880 Gene3D G3DSA:1.10.10.10 752 880 1.0E-15 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_02470 913e8a9b20adf476fead87fe48a70c4a 880 SUPERFAMILY SSF46894 824 880 2.65E-15 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MB46_02470 913e8a9b20adf476fead87fe48a70c4a 880 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 859 871 2.9E-8 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_02470 913e8a9b20adf476fead87fe48a70c4a 880 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 843 859 2.9E-8 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_02470 913e8a9b20adf476fead87fe48a70c4a 880 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 829 843 2.9E-8 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_04790 ebb366e36b72b8468b1a2cd25be9481e 154 Pfam PF09424 Yqey-like protein 5 153 7.8E-33 T 14-10-2018 IPR019004 Uncharacterised protein YqeY/AIM41 MB46_04790 ebb366e36b72b8468b1a2cd25be9481e 154 Gene3D G3DSA:1.10.1510.10 1 93 1.9E-15 T 14-10-2018 MB46_04790 ebb366e36b72b8468b1a2cd25be9481e 154 SUPERFAMILY SSF89095 3 154 5.13E-29 T 14-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 MB46_04790 ebb366e36b72b8468b1a2cd25be9481e 154 Gene3D G3DSA:1.10.10.410 94 154 3.3E-12 T 14-10-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal MB46_12445 2a328907f3585823fefc324472a04edc 280 Gene3D G3DSA:1.10.3720.10 49 268 4.9E-46 T 14-10-2018 IPR035906 MetI-like superfamily MB46_12445 2a328907f3585823fefc324472a04edc 280 SUPERFAMILY SSF161098 61 248 3.14E-37 T 14-10-2018 IPR035906 MetI-like superfamily MB46_12445 2a328907f3585823fefc324472a04edc 280 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 61 157 4.4E-20 T 14-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 MB46_12445 2a328907f3585823fefc324472a04edc 280 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 81 266 5.8E-19 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_15720 318de7698833e76f2d7a366238202390 470 Pfam PF17101 Stealth protein CR1, conserved region 1 161 184 5.5E-7 T 14-10-2018 IPR031358 Stealth protein CR1, conserved region 1 MB46_15720 318de7698833e76f2d7a366238202390 470 Pfam PF17102 Stealth protein CR3, conserved region 3 349 395 5.7E-15 T 14-10-2018 IPR031357 Stealth protein CR3, conserved region 3 MB46_15720 318de7698833e76f2d7a366238202390 470 Pfam PF17103 Stealth protein CR4, conserved region 4 425 470 4.0E-13 T 14-10-2018 IPR031356 Stealth protein CR4, conserved region 4 MB46_15720 318de7698833e76f2d7a366238202390 470 Pfam PF11380 Stealth protein CR2, conserved region 2 199 303 1.1E-38 T 14-10-2018 IPR021520 Stealth protein CR2, conserved region 2 GO:0016772 MB46_14865 cf02ef1994dd0c2b36d8477942d3c45d 326 Gene3D G3DSA:2.60.120.260 2 132 7.9E-13 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily MB46_14865 cf02ef1994dd0c2b36d8477942d3c45d 326 SUPERFAMILY SSF52266 135 321 9.44E-26 T 14-10-2018 MB46_14865 cf02ef1994dd0c2b36d8477942d3c45d 326 Pfam PF14606 GDSL-like Lipase/Acylhydrolase family 140 321 7.5E-23 T 14-10-2018 IPR013830 SGNH hydrolase-type esterase domain MB46_14865 cf02ef1994dd0c2b36d8477942d3c45d 326 Gene3D G3DSA:3.40.50.1110 136 325 1.1E-69 T 14-10-2018 IPR036514 SGNH hydrolase superfamily MB46_04680 3f38f1ae9bb805e9a9807c9b602900d8 557 Pfam PF00890 FAD binding domain 13 537 4.5E-100 T 14-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 MB46_04680 3f38f1ae9bb805e9a9807c9b602900d8 557 PIRSF PIRSF036654 7 555 7.0E-261 T 14-10-2018 IPR014614 Uncharacterised conserved protein UCP036654 GO:0016627|GO:0055114 MB46_04680 3f38f1ae9bb805e9a9807c9b602900d8 557 Gene3D G3DSA:3.50.50.60 12 551 2.6E-65 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_04680 3f38f1ae9bb805e9a9807c9b602900d8 557 Gene3D G3DSA:3.90.700.10 280 485 2.6E-65 T 14-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 MB46_04680 3f38f1ae9bb805e9a9807c9b602900d8 557 SUPERFAMILY SSF51905 10 553 1.42E-37 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_05740 74ecf24185d0141f55f93da039a3631f 381 SUPERFAMILY SSF53822 99 379 1.16E-43 T 14-10-2018 IPR028082 Periplasmic binding protein-like I MB46_05740 74ecf24185d0141f55f93da039a3631f 381 Gene3D G3DSA:3.40.50.2300 100 371 5.6E-60 T 14-10-2018 MB46_05740 74ecf24185d0141f55f93da039a3631f 381 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 14-10-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 MB46_05740 74ecf24185d0141f55f93da039a3631f 381 SUPERFAMILY SSF46785 4 59 1.69E-13 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_05740 74ecf24185d0141f55f93da039a3631f 381 Gene3D G3DSA:3.40.50.2300 204 376 5.6E-60 T 14-10-2018 MB46_05740 74ecf24185d0141f55f93da039a3631f 381 SMART SM00420 6 58 1.2E-16 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MB46_05740 74ecf24185d0141f55f93da039a3631f 381 Gene3D G3DSA:1.10.10.10 4 51 2.8E-6 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_05740 74ecf24185d0141f55f93da039a3631f 381 Pfam PF13377 Periplasmic binding protein-like domain 213 379 4.8E-29 T 14-10-2018 MB46_05740 74ecf24185d0141f55f93da039a3631f 381 Pfam PF08220 DeoR-like helix-turn-helix domain 6 57 5.8E-16 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MB46_05740 74ecf24185d0141f55f93da039a3631f 381 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 4.2E-8 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MB46_05740 74ecf24185d0141f55f93da039a3631f 381 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 4.2E-8 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MB46_12505 fd4c4b868276d7dd7ce7781d8b90cbae 382 Pfam PF00155 Aminotransferase class I and II 35 378 1.9E-36 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MB46_12505 fd4c4b868276d7dd7ce7781d8b90cbae 382 TIGRFAM TIGR03539 DapC_actino: succinyldiaminopimelate transaminase 12 378 3.4E-172 T 14-10-2018 IPR019880 4-dedimethylamino-4-oxo-anhydrotetracycline transaminase OxyQ MB46_12505 fd4c4b868276d7dd7ce7781d8b90cbae 382 Gene3D G3DSA:3.90.1150.10 25 370 2.0E-78 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MB46_12505 fd4c4b868276d7dd7ce7781d8b90cbae 382 Gene3D G3DSA:3.40.640.10 46 285 2.0E-78 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MB46_12505 fd4c4b868276d7dd7ce7781d8b90cbae 382 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 236 249 - T 14-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 MB46_12505 fd4c4b868276d7dd7ce7781d8b90cbae 382 SUPERFAMILY SSF53383 25 379 8.11E-74 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MB46_06445 d151de6b437a65ea65b371bb8783bfc6 274 ProSitePatterns PS00211 ABC transporters family signature. 151 165 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_06445 d151de6b437a65ea65b371bb8783bfc6 274 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 230 266 5.8E-6 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MB46_06445 d151de6b437a65ea65b371bb8783bfc6 274 Pfam PF00005 ABC transporter 28 178 2.3E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_06445 d151de6b437a65ea65b371bb8783bfc6 274 SMART SM00382 37 228 3.5E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_06445 d151de6b437a65ea65b371bb8783bfc6 274 Gene3D G3DSA:3.40.50.300 3 273 1.3E-85 T 14-10-2018 MB46_06445 d151de6b437a65ea65b371bb8783bfc6 274 SUPERFAMILY SSF52540 5 250 8.52E-73 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_13230 a65bd6f2733c45c59d2be619705d4653 115 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 13 78 6.0E-30 T 14-10-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 MB46_13230 a65bd6f2733c45c59d2be619705d4653 115 Gene3D G3DSA:3.90.470.20 1 115 1.6E-28 T 14-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 MB46_13230 a65bd6f2733c45c59d2be619705d4653 115 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 4 91 1.3E-11 T 14-10-2018 IPR008278 4'-phosphopantetheinyl transferase domain GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 MB46_13230 a65bd6f2733c45c59d2be619705d4653 115 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 2 114 5.1E-19 T 14-10-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 MB46_13230 a65bd6f2733c45c59d2be619705d4653 115 SUPERFAMILY SSF56214 1 114 8.37E-24 T 14-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 MB46_13230 a65bd6f2733c45c59d2be619705d4653 115 Hamap MF_00101 Holo-[acyl-carrier-protein] synthase [acpS]. 3 115 18.689 T 14-10-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 MB46_11390 86fc0823a144e4565e66eecf704f30b2 337 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 323 7.9E-58 T 14-10-2018 IPR016040 NAD(P)-binding domain MB46_11390 86fc0823a144e4565e66eecf704f30b2 337 Gene3D G3DSA:3.40.50.720 3 273 1.2E-138 T 14-10-2018 MB46_11390 86fc0823a144e4565e66eecf704f30b2 337 Gene3D G3DSA:3.90.25.10 193 328 1.2E-138 T 14-10-2018 MB46_11390 86fc0823a144e4565e66eecf704f30b2 337 SUPERFAMILY SSF51735 1 335 4.2E-95 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_11390 86fc0823a144e4565e66eecf704f30b2 337 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 2 334 2.0E-133 T 14-10-2018 IPR005886 UDP-glucose 4-epimerase GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-5609977|Reactome: R-HSA-70370 MB46_08755 6d370f1aa85a84ab88462bf3fec5b23a 85 ProSitePatterns PS00194 Thioredoxin family active site. 10 28 - T 14-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 MB46_08755 6d370f1aa85a84ab88462bf3fec5b23a 85 Gene3D G3DSA:3.40.30.10 7 85 8.6E-22 T 14-10-2018 MB46_08755 6d370f1aa85a84ab88462bf3fec5b23a 85 TIGRFAM TIGR02200 GlrX_actino: glutaredoxin-like protein 9 83 6.5E-28 T 14-10-2018 IPR011915 Glutaredoxin-like protein, actinobacteria MB46_08755 6d370f1aa85a84ab88462bf3fec5b23a 85 SUPERFAMILY SSF52833 9 74 4.75E-13 T 14-10-2018 IPR036249 Thioredoxin-like superfamily MB46_08755 6d370f1aa85a84ab88462bf3fec5b23a 85 Pfam PF00462 Glutaredoxin 10 65 6.6E-12 T 14-10-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 MB46_12385 e54cd4c16935c985dafc8505bc60bd33 373 Pfam PF01883 Iron-sulfur cluster assembly protein 8 77 6.3E-18 T 14-10-2018 IPR002744 MIP18 family-like MB46_12385 e54cd4c16935c985dafc8505bc60bd33 373 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 111 356 1.1E-83 T 14-10-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 MB46_12385 e54cd4c16935c985dafc8505bc60bd33 373 Hamap MF_02040 Iron-sulfur cluster carrier protein. 105 357 32.166 T 14-10-2018 IPR019591 Mrp/NBP35 ATP-binding protein MB46_12385 e54cd4c16935c985dafc8505bc60bd33 373 SUPERFAMILY SSF117916 2 94 1.9E-23 T 14-10-2018 IPR034904 Fe-S cluster assembly domain superfamily MB46_12385 e54cd4c16935c985dafc8505bc60bd33 373 SUPERFAMILY SSF52540 111 357 1.05E-49 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_12385 e54cd4c16935c985dafc8505bc60bd33 373 Gene3D G3DSA:3.40.50.300 105 353 6.6E-64 T 14-10-2018 MB46_12385 e54cd4c16935c985dafc8505bc60bd33 373 Gene3D G3DSA:3.30.300.130 1 96 4.8E-21 T 14-10-2018 IPR034904 Fe-S cluster assembly domain superfamily MB46_03980 fc3fa826814a130d9bcdc0be2c792d82 244 Pfam PF00977 Histidine biosynthesis protein 8 233 1.3E-64 T 14-10-2018 IPR006062 Histidine biosynthesis GO:0000105 MB46_03980 fc3fa826814a130d9bcdc0be2c792d82 244 SUPERFAMILY SSF51366 7 239 3.14E-64 T 14-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 MB46_03980 fc3fa826814a130d9bcdc0be2c792d82 244 Gene3D G3DSA:3.20.20.70 1 244 4.0E-95 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MB46_03980 fc3fa826814a130d9bcdc0be2c792d82 244 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 7 240 33.167 T 14-10-2018 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 MB46_03980 fc3fa826814a130d9bcdc0be2c792d82 244 TIGRFAM TIGR01919 hisA-trpF: bifunctional HisA/TrpF protein 6 241 1.1E-115 T 14-10-2018 IPR010188 Bifunctional HisA/TrpF GO:0000105|GO:0000162|GO:0003949|GO:0004640|GO:0005737 KEGG: 00340+5.3.1.16 MB46_10530 0693aad08f06238878b4e0ba1f237a76 452 Pfam PF07687 Peptidase dimerisation domain 204 351 2.5E-16 T 14-10-2018 IPR011650 Peptidase M20, dimerisation domain MB46_10530 0693aad08f06238878b4e0ba1f237a76 452 SUPERFAMILY SSF55031 208 349 6.28E-10 T 14-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain MB46_10530 0693aad08f06238878b4e0ba1f237a76 452 Gene3D G3DSA:3.30.70.360 293 362 3.1E-11 T 14-10-2018 MB46_10530 0693aad08f06238878b4e0ba1f237a76 452 Pfam PF01546 Peptidase family M20/M25/M40 85 449 1.6E-29 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 MB46_10530 0693aad08f06238878b4e0ba1f237a76 452 SUPERFAMILY SSF53187 11 451 4.29E-44 T 14-10-2018 MB46_10530 0693aad08f06238878b4e0ba1f237a76 452 Gene3D G3DSA:3.40.630.10 363 437 3.1E-11 T 14-10-2018 MB46_10530 0693aad08f06238878b4e0ba1f237a76 452 Gene3D G3DSA:3.40.630.10 13 251 1.6E-40 T 14-10-2018 MB46_16505 86fc4245413b70400727beb39fb3503f 417 Pfam PF04055 Radical SAM superfamily 164 344 6.0E-16 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MB46_16505 86fc4245413b70400727beb39fb3503f 417 Gene3D G3DSA:3.20.20.70 123 404 4.0E-91 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MB46_16505 86fc4245413b70400727beb39fb3503f 417 SUPERFAMILY SSF102114 154 378 2.35E-13 T 14-10-2018 MB46_16505 86fc4245413b70400727beb39fb3503f 417 Gene3D G3DSA:1.10.150.530 60 118 2.0E-8 T 14-10-2018 MB46_16505 86fc4245413b70400727beb39fb3503f 417 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 60 415 2.1E-94 T 14-10-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 MB46_16505 86fc4245413b70400727beb39fb3503f 417 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 59 417 65.688 T 14-10-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 MB46_16505 86fc4245413b70400727beb39fb3503f 417 PIRSF PIRSF006004 52 417 1.8E-115 T 14-10-2018 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 MB46_04825 e793ceda8f5c00e1d963585f2d33fa89 187 SUPERFAMILY SSF47240 9 164 3.07E-34 T 14-10-2018 IPR009078 Ferritin-like superfamily MB46_04825 e793ceda8f5c00e1d963585f2d33fa89 187 PIRSF PIRSF005900 4 169 7.9E-46 T 14-10-2018 IPR002177 DNA-binding protein Dps MB46_04825 e793ceda8f5c00e1d963585f2d33fa89 187 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 141 159 6.1E-11 T 14-10-2018 IPR002177 DNA-binding protein Dps MB46_04825 e793ceda8f5c00e1d963585f2d33fa89 187 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 70 86 6.1E-11 T 14-10-2018 IPR002177 DNA-binding protein Dps MB46_04825 e793ceda8f5c00e1d963585f2d33fa89 187 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 46 62 6.1E-11 T 14-10-2018 IPR002177 DNA-binding protein Dps MB46_04825 e793ceda8f5c00e1d963585f2d33fa89 187 ProSitePatterns PS00818 Dps protein family signature 1. 46 62 - T 14-10-2018 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 MB46_04825 e793ceda8f5c00e1d963585f2d33fa89 187 Gene3D G3DSA:1.20.1260.10 7 172 6.3E-44 T 14-10-2018 IPR012347 Ferritin-like MB46_04825 e793ceda8f5c00e1d963585f2d33fa89 187 Pfam PF00210 Ferritin-like domain 27 165 4.8E-18 T 14-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 MB46_06595 ce75abaaa8ac09759515819f5347e5aa 313 SUPERFAMILY SSF56300 15 263 8.47E-52 T 14-10-2018 MB46_06595 ce75abaaa8ac09759515819f5347e5aa 313 Hamap MF_00905 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA [cpdA]. 13 266 34.143 T 14-10-2018 IPR026575 3,5-cyclic adenosine monophosphate phosphodiesterase CpdA GO:0004115 KEGG: 00230+3.1.4.53 MB46_06595 ce75abaaa8ac09759515819f5347e5aa 313 Gene3D G3DSA:3.60.21.10 1 297 3.4E-109 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like MB46_06595 ce75abaaa8ac09759515819f5347e5aa 313 Pfam PF00149 Calcineurin-like phosphoesterase 16 208 3.0E-14 T 14-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 MB46_01220 0ebf2033309bf617b12f480e81652bf7 472 SUPERFAMILY SSF51905 10 400 1.3E-29 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_01220 0ebf2033309bf617b12f480e81652bf7 472 Gene3D G3DSA:3.50.50.60 2 358 4.7E-32 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_01220 0ebf2033309bf617b12f480e81652bf7 472 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 10 29 2.9E-7 T 14-10-2018 MB46_01220 0ebf2033309bf617b12f480e81652bf7 472 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 204 222 2.9E-7 T 14-10-2018 MB46_01220 0ebf2033309bf617b12f480e81652bf7 472 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 305 321 2.9E-7 T 14-10-2018 MB46_01220 0ebf2033309bf617b12f480e81652bf7 472 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 204 229 3.5E-6 T 14-10-2018 MB46_01220 0ebf2033309bf617b12f480e81652bf7 472 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 306 320 3.5E-6 T 14-10-2018 MB46_01220 0ebf2033309bf617b12f480e81652bf7 472 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 9 31 3.5E-6 T 14-10-2018 MB46_01220 0ebf2033309bf617b12f480e81652bf7 472 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 10 330 1.2E-6 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MB46_15270 8d8e7113f2613ae4c201ca330d50d46c 572 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 252 535 1.1E-71 T 14-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 MB46_15270 8d8e7113f2613ae4c201ca330d50d46c 572 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 429 444 6.1E-12 T 14-10-2018 MB46_15270 8d8e7113f2613ae4c201ca330d50d46c 572 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 446 461 6.1E-12 T 14-10-2018 MB46_15270 8d8e7113f2613ae4c201ca330d50d46c 572 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 285 304 6.1E-12 T 14-10-2018 MB46_15270 8d8e7113f2613ae4c201ca330d50d46c 572 Pfam PF05524 PEP-utilising enzyme, N-terminal 6 124 1.6E-17 T 14-10-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 MB46_15270 8d8e7113f2613ae4c201ca330d50d46c 572 SUPERFAMILY SSF47831 40 141 1.96E-17 T 14-10-2018 IPR036618 PtsI, HPr-binding domain superfamily GO:0009401 MB46_15270 8d8e7113f2613ae4c201ca330d50d46c 572 PIRSF PIRSF000732 2 567 1.6E-137 T 14-10-2018 IPR024692 Phosphotransferase system, enzyme I GO:0008965|GO:0009401 MB46_15270 8d8e7113f2613ae4c201ca330d50d46c 572 Gene3D G3DSA:3.20.20.60 233 564 1.9E-89 T 14-10-2018 MB46_15270 8d8e7113f2613ae4c201ca330d50d46c 572 SUPERFAMILY SSF52009 123 236 2.88E-27 T 14-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 MB46_15270 8d8e7113f2613ae4c201ca330d50d46c 572 SUPERFAMILY SSF51621 240 537 5.14E-76 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 MB46_15270 8d8e7113f2613ae4c201ca330d50d46c 572 Pfam PF00391 PEP-utilising enzyme, mobile domain 154 222 1.9E-19 T 14-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 MB46_15270 8d8e7113f2613ae4c201ca330d50d46c 572 Gene3D G3DSA:1.10.274.10 23 144 4.1E-48 T 14-10-2018 IPR036618 PtsI, HPr-binding domain superfamily GO:0009401 MB46_15270 8d8e7113f2613ae4c201ca330d50d46c 572 Gene3D G3DSA:3.50.30.10 6 230 4.1E-48 T 14-10-2018 MB46_17515 610e7189ee50c08bb662b8c38e0e3309 403 PRINTS PR01270 Histone deacetylase superfamily signature 258 268 2.7E-17 T 14-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 MB46_17515 610e7189ee50c08bb662b8c38e0e3309 403 PRINTS PR01270 Histone deacetylase superfamily signature 139 162 2.7E-17 T 14-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 MB46_17515 610e7189ee50c08bb662b8c38e0e3309 403 PRINTS PR01270 Histone deacetylase superfamily signature 172 187 2.7E-17 T 14-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 MB46_17515 610e7189ee50c08bb662b8c38e0e3309 403 Gene3D G3DSA:3.40.800.20 13 386 4.8E-98 T 14-10-2018 IPR037138 Histone deacetylase domain superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 MB46_17515 610e7189ee50c08bb662b8c38e0e3309 403 PRINTS PR01272 Acetoin utilisation ACUC protein signature 25 45 2.4E-9 T 14-10-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 MB46_17515 610e7189ee50c08bb662b8c38e0e3309 403 PRINTS PR01272 Acetoin utilisation ACUC protein signature 95 109 2.4E-9 T 14-10-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 MB46_17515 610e7189ee50c08bb662b8c38e0e3309 403 PRINTS PR01272 Acetoin utilisation ACUC protein signature 116 129 2.4E-9 T 14-10-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 MB46_17515 610e7189ee50c08bb662b8c38e0e3309 403 SUPERFAMILY SSF52768 13 372 7.19E-98 T 14-10-2018 IPR023696 Ureohydrolase domain superfamily MB46_17515 610e7189ee50c08bb662b8c38e0e3309 403 Pfam PF00850 Histone deacetylase domain 31 328 1.5E-70 T 14-10-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 MB46_07415 eb6df6a0c0ee6f71c03a7c9a8b6aaa66 313 SUPERFAMILY SSF63817 112 251 3.53E-42 T 14-10-2018 IPR023365 Sortase domain superfamily MB46_07415 eb6df6a0c0ee6f71c03a7c9a8b6aaa66 313 TIGRFAM TIGR01076 sortase_fam: sortase 123 252 3.3E-45 T 14-10-2018 IPR005754 Sortase family MB46_07415 eb6df6a0c0ee6f71c03a7c9a8b6aaa66 313 Gene3D G3DSA:2.40.260.10 47 260 1.7E-60 T 14-10-2018 IPR023365 Sortase domain superfamily MB46_07415 eb6df6a0c0ee6f71c03a7c9a8b6aaa66 313 Pfam PF04203 Sortase family 125 250 1.5E-22 T 14-10-2018 IPR005754 Sortase family MB46_18720 f5e4718110339c276a86979c6ee819e3 257 SUPERFAMILY SSF56436 8 219 1.7E-43 T 14-10-2018 IPR016187 C-type lectin fold MB46_18720 f5e4718110339c276a86979c6ee819e3 257 Gene3D G3DSA:3.90.1580.10 8 218 3.0E-54 T 14-10-2018 MB46_18720 f5e4718110339c276a86979c6ee819e3 257 Pfam PF03781 Sulfatase-modifying factor enzyme 1 12 218 2.7E-29 T 14-10-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 MB46_03710 3912fbde0c0f2f188980fda6c81d69f3 242 ProSitePatterns PS00211 ABC transporters family signature. 128 142 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_03710 3912fbde0c0f2f188980fda6c81d69f3 242 SMART SM00382 27 209 1.5E-7 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_03710 3912fbde0c0f2f188980fda6c81d69f3 242 SUPERFAMILY SSF52540 3 216 2.56E-54 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_03710 3912fbde0c0f2f188980fda6c81d69f3 242 Pfam PF00005 ABC transporter 18 155 1.0E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_03710 3912fbde0c0f2f188980fda6c81d69f3 242 Gene3D G3DSA:3.40.50.300 1 238 6.7E-59 T 14-10-2018 MB46_06745 5f2b07a9131210e999fc0cdc7b6076da 307 SUPERFAMILY SSF52402 1 132 5.94E-16 T 14-10-2018 MB46_06745 5f2b07a9131210e999fc0cdc7b6076da 307 Pfam PF00582 Universal stress protein family 140 274 4.7E-16 T 14-10-2018 IPR006016 UspA MB46_06745 5f2b07a9131210e999fc0cdc7b6076da 307 Pfam PF00582 Universal stress protein family 1 130 2.9E-9 T 14-10-2018 IPR006016 UspA MB46_06745 5f2b07a9131210e999fc0cdc7b6076da 307 SUPERFAMILY SSF52402 140 276 3.1E-18 T 14-10-2018 MB46_06745 5f2b07a9131210e999fc0cdc7b6076da 307 PRINTS PR01438 Universal stress protein signature 137 155 9.3E-9 T 14-10-2018 IPR006015 Universal stress protein A MB46_06745 5f2b07a9131210e999fc0cdc7b6076da 307 PRINTS PR01438 Universal stress protein signature 254 276 9.3E-9 T 14-10-2018 IPR006015 Universal stress protein A MB46_06745 5f2b07a9131210e999fc0cdc7b6076da 307 PRINTS PR01438 Universal stress protein signature 236 248 9.3E-9 T 14-10-2018 IPR006015 Universal stress protein A MB46_06745 5f2b07a9131210e999fc0cdc7b6076da 307 Gene3D G3DSA:3.40.50.620 135 287 9.1E-28 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MB46_06745 5f2b07a9131210e999fc0cdc7b6076da 307 Gene3D G3DSA:3.40.50.620 1 134 2.4E-26 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MB46_10785 eb54eaea8f3c075f90d275dfc0532639 312 Pfam PF14561 Tetratricopeptide repeat 230 312 5.3E-18 T 14-10-2018 MB46_10785 eb54eaea8f3c075f90d275dfc0532639 312 SUPERFAMILY SSF48452 176 291 2.13E-5 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MB46_10785 eb54eaea8f3c075f90d275dfc0532639 312 SUPERFAMILY SSF52833 43 147 5.7E-19 T 14-10-2018 IPR036249 Thioredoxin-like superfamily MB46_10785 eb54eaea8f3c075f90d275dfc0532639 312 Gene3D G3DSA:3.40.30.10 40 149 2.4E-17 T 14-10-2018 MB46_10785 eb54eaea8f3c075f90d275dfc0532639 312 Gene3D G3DSA:1.25.40.10 227 312 6.4E-8 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MB46_10785 eb54eaea8f3c075f90d275dfc0532639 312 Pfam PF00085 Thioredoxin 46 145 3.0E-10 T 14-10-2018 IPR013766 Thioredoxin domain GO:0045454 MB46_08715 d46b1c2285811af1a92816bd08ebfa83 208 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 69 91 - T 14-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 MB46_08715 d46b1c2285811af1a92816bd08ebfa83 208 Gene3D G3DSA:1.20.120.1760 7 205 3.2E-68 T 14-10-2018 MB46_08715 d46b1c2285811af1a92816bd08ebfa83 208 Pfam PF01066 CDP-alcohol phosphatidyltransferase 27 91 3.1E-8 T 14-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 MB46_05715 d2a4729caf129df3a40513c96e11e511 491 Gene3D G3DSA:1.20.1250.20 271 474 4.5E-19 T 14-10-2018 MB46_05715 d2a4729caf129df3a40513c96e11e511 491 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 20 426 7.0E-92 T 14-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 MB46_05715 d2a4729caf129df3a40513c96e11e511 491 Pfam PF07690 Major Facilitator Superfamily 23 418 1.4E-52 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MB46_05715 d2a4729caf129df3a40513c96e11e511 491 PRINTS PR01036 Tetracycline resistance protein TetB signature 22 46 7.5E-12 T 14-10-2018 MB46_05715 d2a4729caf129df3a40513c96e11e511 491 PRINTS PR01036 Tetracycline resistance protein TetB signature 113 133 7.5E-12 T 14-10-2018 MB46_05715 d2a4729caf129df3a40513c96e11e511 491 PRINTS PR01036 Tetracycline resistance protein TetB signature 143 167 7.5E-12 T 14-10-2018 MB46_05715 d2a4729caf129df3a40513c96e11e511 491 PRINTS PR01036 Tetracycline resistance protein TetB signature 409 428 7.5E-12 T 14-10-2018 MB46_05715 d2a4729caf129df3a40513c96e11e511 491 SUPERFAMILY SSF103473 11 471 1.57E-62 T 14-10-2018 IPR036259 MFS transporter superfamily MB46_05715 d2a4729caf129df3a40513c96e11e511 491 Gene3D G3DSA:1.20.1720.10 20 229 1.1E-41 T 14-10-2018 MB46_08985 1a831e358a5ec72d47881a7b602c50b2 138 SMART SM00562 3 138 6.1E-65 T 14-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MB46_08985 1a831e358a5ec72d47881a7b602c50b2 138 PRINTS PR01243 Nucleoside diphosphate kinase signature 6 28 6.9E-33 T 14-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MB46_08985 1a831e358a5ec72d47881a7b602c50b2 138 PRINTS PR01243 Nucleoside diphosphate kinase signature 50 69 6.9E-33 T 14-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MB46_08985 1a831e358a5ec72d47881a7b602c50b2 138 PRINTS PR01243 Nucleoside diphosphate kinase signature 118 137 6.9E-33 T 14-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MB46_08985 1a831e358a5ec72d47881a7b602c50b2 138 PRINTS PR01243 Nucleoside diphosphate kinase signature 70 87 6.9E-33 T 14-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MB46_08985 1a831e358a5ec72d47881a7b602c50b2 138 SUPERFAMILY SSF54919 3 137 1.7E-51 T 14-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MB46_08985 1a831e358a5ec72d47881a7b602c50b2 138 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 118 126 - T 14-10-2018 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MB46_08985 1a831e358a5ec72d47881a7b602c50b2 138 Pfam PF00334 Nucleoside diphosphate kinase 4 137 1.5E-51 T 14-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MB46_08985 1a831e358a5ec72d47881a7b602c50b2 138 Gene3D G3DSA:3.30.70.141 1 138 8.5E-55 T 14-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MB46_08985 1a831e358a5ec72d47881a7b602c50b2 138 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 3 138 29.363 T 14-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MB46_15840 a858082d4896f1d8b6c151da03b1e452 589 ProSitePatterns PS01182 Glycosyl hydrolases family 35 putative active site. 147 159 - T 14-10-2018 IPR019801 Glycoside hydrolase, family 35, conserved site GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 MB46_15840 a858082d4896f1d8b6c151da03b1e452 589 PIRSF PIRSF006336 2 586 3.0E-181 T 14-10-2018 IPR026283 Beta-galactosidase 1-like GO:0004565 MB46_15840 a858082d4896f1d8b6c151da03b1e452 589 Gene3D G3DSA:3.20.20.80 1 271 1.1E-97 T 14-10-2018 MB46_15840 a858082d4896f1d8b6c151da03b1e452 589 Gene3D G3DSA:2.60.120.260 347 478 1.1E-90 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily MB46_15840 a858082d4896f1d8b6c151da03b1e452 589 PRINTS PR00742 Glycosyl hydrolase family 35 signature 527 543 9.0E-55 T 14-10-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 MB46_15840 a858082d4896f1d8b6c151da03b1e452 589 PRINTS PR00742 Glycosyl hydrolase family 35 signature 90 109 9.0E-55 T 14-10-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 MB46_15840 a858082d4896f1d8b6c151da03b1e452 589 PRINTS PR00742 Glycosyl hydrolase family 35 signature 14 31 9.0E-55 T 14-10-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 MB46_15840 a858082d4896f1d8b6c151da03b1e452 589 PRINTS PR00742 Glycosyl hydrolase family 35 signature 35 53 9.0E-55 T 14-10-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 MB46_15840 a858082d4896f1d8b6c151da03b1e452 589 PRINTS PR00742 Glycosyl hydrolase family 35 signature 231 246 9.0E-55 T 14-10-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 MB46_15840 a858082d4896f1d8b6c151da03b1e452 589 PRINTS PR00742 Glycosyl hydrolase family 35 signature 293 309 9.0E-55 T 14-10-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 MB46_15840 a858082d4896f1d8b6c151da03b1e452 589 PRINTS PR00742 Glycosyl hydrolase family 35 signature 145 160 9.0E-55 T 14-10-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 MB46_15840 a858082d4896f1d8b6c151da03b1e452 589 PRINTS PR00742 Glycosyl hydrolase family 35 signature 267 282 9.0E-55 T 14-10-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 MB46_15840 a858082d4896f1d8b6c151da03b1e452 589 Gene3D G3DSA:2.60.120.260 272 569 1.1E-90 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily MB46_15840 a858082d4896f1d8b6c151da03b1e452 589 SUPERFAMILY SSF49785 439 577 2.19E-25 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily MB46_15840 a858082d4896f1d8b6c151da03b1e452 589 Pfam PF01301 Glycosyl hydrolases family 35 11 323 1.6E-110 T 14-10-2018 IPR031330 Glycoside hydrolase 35, catalytic domain KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 MB46_15840 a858082d4896f1d8b6c151da03b1e452 589 SUPERFAMILY SSF51445 4 326 1.91E-100 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily MB46_19855 af4b59394591400c4ae60947c40170f9 124 Gene3D G3DSA:3.90.1150.30 8 124 6.8E-30 T 14-10-2018 IPR038056 YjbR-like superfamily MB46_19855 af4b59394591400c4ae60947c40170f9 124 SUPERFAMILY SSF142906 12 120 5.89E-27 T 14-10-2018 IPR038056 YjbR-like superfamily MB46_19855 af4b59394591400c4ae60947c40170f9 124 Pfam PF04237 YjbR 18 108 7.0E-19 T 14-10-2018 IPR007351 Uncharacterised protein YjbR MB46_00705 5b53a3f69e82d1f9cadab22da9b93c6a 629 SUPERFAMILY SSF52540 337 587 5.1E-71 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_00705 5b53a3f69e82d1f9cadab22da9b93c6a 629 Pfam PF00005 ABC transporter 365 520 2.2E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_00705 5b53a3f69e82d1f9cadab22da9b93c6a 629 Gene3D G3DSA:1.20.1560.10 1 332 2.8E-65 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MB46_00705 5b53a3f69e82d1f9cadab22da9b93c6a 629 SMART SM00382 374 567 9.4E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_00705 5b53a3f69e82d1f9cadab22da9b93c6a 629 Pfam PF00664 ABC transporter transmembrane region 28 298 2.6E-38 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 MB46_00705 5b53a3f69e82d1f9cadab22da9b93c6a 629 Gene3D G3DSA:3.40.50.300 336 597 1.3E-74 T 14-10-2018 MB46_00705 5b53a3f69e82d1f9cadab22da9b93c6a 629 ProSitePatterns PS00211 ABC transporters family signature. 493 507 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_00705 5b53a3f69e82d1f9cadab22da9b93c6a 629 SUPERFAMILY SSF90123 15 324 2.75E-62 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MB46_02385 6f65ea3a3f82c432339d2523426da33c 289 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 16 215 2.3E-27 T 14-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 MB46_02385 6f65ea3a3f82c432339d2523426da33c 289 Gene3D G3DSA:3.30.950.10 125 240 2.4E-41 T 14-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 MB46_02385 6f65ea3a3f82c432339d2523426da33c 289 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 15 236 33.113 T 14-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 MB46_02385 6f65ea3a3f82c432339d2523426da33c 289 Gene3D G3DSA:3.40.1010.10 4 124 8.4E-32 T 14-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 MB46_02385 6f65ea3a3f82c432339d2523426da33c 289 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 18 285 1.5E-68 T 14-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 MB46_02385 6f65ea3a3f82c432339d2523426da33c 289 SUPERFAMILY SSF53790 14 234 3.66E-73 T 14-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 MB46_02385 6f65ea3a3f82c432339d2523426da33c 289 PIRSF PIRSF005917 4 289 5.2E-95 T 14-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 MB46_10580 419751dc6400f6388022410ffd013f0e 97 Pfam PF07561 Domain of Unknown Function (DUF1540) 9 42 1.4E-5 T 14-10-2018 IPR011437 Domain of unknown function DUF1540 MB46_10580 419751dc6400f6388022410ffd013f0e 97 Pfam PF07561 Domain of Unknown Function (DUF1540) 61 90 0.0052 T 14-10-2018 IPR011437 Domain of unknown function DUF1540 MB46_04730 2e95ccbacd5a0dd682df1628abfc9503 256 Gene3D G3DSA:1.10.10.10 18 85 4.6E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_04730 2e95ccbacd5a0dd682df1628abfc9503 256 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 56 72 4.2E-10 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MB46_04730 2e95ccbacd5a0dd682df1628abfc9503 256 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 42 56 4.2E-10 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MB46_04730 2e95ccbacd5a0dd682df1628abfc9503 256 SMART SM00345 24 82 1.9E-12 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MB46_04730 2e95ccbacd5a0dd682df1628abfc9503 256 SMART SM00866 102 240 2.2E-40 T 14-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 MB46_04730 2e95ccbacd5a0dd682df1628abfc9503 256 Pfam PF00392 Bacterial regulatory proteins, gntR family 28 82 7.7E-15 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MB46_04730 2e95ccbacd5a0dd682df1628abfc9503 256 Pfam PF07702 UTRA domain 103 240 7.9E-37 T 14-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 MB46_04730 2e95ccbacd5a0dd682df1628abfc9503 256 SUPERFAMILY SSF64288 70 247 8.48E-49 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily MB46_04730 2e95ccbacd5a0dd682df1628abfc9503 256 SUPERFAMILY SSF46785 13 86 2.3E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_04730 2e95ccbacd5a0dd682df1628abfc9503 256 Gene3D G3DSA:3.40.1410.10 86 249 3.1E-51 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily MB46_12205 8b1b975932f268cb976935f024189234 184 Pfam PF06042 Nucleotidyltransferase 17 178 1.3E-48 T 14-10-2018 IPR009267 Putative nucleotidyltransferase MB46_00870 fd822a1da467a574081831c0a1b6a95c 545 SUPERFAMILY SSF103473 16 200 5.89E-42 T 14-10-2018 IPR036259 MFS transporter superfamily MB46_00870 fd822a1da467a574081831c0a1b6a95c 545 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 20 432 6.0E-75 T 14-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 MB46_00870 fd822a1da467a574081831c0a1b6a95c 545 Pfam PF07690 Major Facilitator Superfamily 27 420 6.7E-52 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MB46_00870 fd822a1da467a574081831c0a1b6a95c 545 PRINTS PR01036 Tetracycline resistance protein TetB signature 411 430 7.7E-9 T 14-10-2018 MB46_00870 fd822a1da467a574081831c0a1b6a95c 545 PRINTS PR01036 Tetracycline resistance protein TetB signature 84 106 7.7E-9 T 14-10-2018 MB46_00870 fd822a1da467a574081831c0a1b6a95c 545 PRINTS PR01036 Tetracycline resistance protein TetB signature 145 169 7.7E-9 T 14-10-2018 MB46_00870 fd822a1da467a574081831c0a1b6a95c 545 PRINTS PR01036 Tetracycline resistance protein TetB signature 25 49 7.7E-9 T 14-10-2018 MB46_00870 fd822a1da467a574081831c0a1b6a95c 545 SUPERFAMILY SSF103473 212 498 2.09E-30 T 14-10-2018 IPR036259 MFS transporter superfamily MB46_00870 fd822a1da467a574081831c0a1b6a95c 545 Gene3D G3DSA:1.20.1720.10 22 214 1.6E-52 T 14-10-2018 MB46_12440 086de5cf52f184345f6254f2d7646ee0 216 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 30 213 3.1E-12 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_12440 086de5cf52f184345f6254f2d7646ee0 216 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 9 106 3.4E-17 T 14-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 MB46_12440 086de5cf52f184345f6254f2d7646ee0 216 Gene3D G3DSA:1.10.3720.10 2 214 3.7E-36 T 14-10-2018 IPR035906 MetI-like superfamily MB46_12440 086de5cf52f184345f6254f2d7646ee0 216 SUPERFAMILY SSF161098 9 197 6.41E-32 T 14-10-2018 IPR035906 MetI-like superfamily MB46_06340 53d5092fd416dbbed998871c66a4a2d9 366 SUPERFAMILY SSF53822 106 363 8.14E-55 T 14-10-2018 IPR028082 Periplasmic binding protein-like I MB46_06340 53d5092fd416dbbed998871c66a4a2d9 366 Gene3D G3DSA:1.10.260.40 2 62 7.6E-21 T 14-10-2018 MB46_06340 53d5092fd416dbbed998871c66a4a2d9 366 Gene3D G3DSA:3.40.50.2300 108 355 3.5E-61 T 14-10-2018 MB46_06340 53d5092fd416dbbed998871c66a4a2d9 366 Gene3D G3DSA:3.40.50.2300 194 323 3.5E-61 T 14-10-2018 MB46_06340 53d5092fd416dbbed998871c66a4a2d9 366 SMART SM00354 4 74 1.6E-23 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MB46_06340 53d5092fd416dbbed998871c66a4a2d9 366 Pfam PF00356 Bacterial regulatory proteins, lacI family 6 51 4.8E-16 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MB46_06340 53d5092fd416dbbed998871c66a4a2d9 366 ProSitePatterns PS00356 LacI-type HTH domain signature. 7 25 - T 14-10-2018 MB46_06340 53d5092fd416dbbed998871c66a4a2d9 366 Pfam PF13377 Periplasmic binding protein-like domain 208 363 1.2E-35 T 14-10-2018 MB46_06340 53d5092fd416dbbed998871c66a4a2d9 366 SUPERFAMILY SSF47413 4 62 8.72E-16 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MB46_05645 313dec20a19076cea0be3694adf390f6 388 Gene3D G3DSA:3.30.420.40 212 354 8.1E-40 T 14-10-2018 MB46_05645 313dec20a19076cea0be3694adf390f6 388 Gene3D G3DSA:3.30.420.40 83 211 7.5E-8 T 14-10-2018 MB46_05645 313dec20a19076cea0be3694adf390f6 388 Pfam PF00480 ROK family 89 379 2.0E-33 T 14-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 MB46_05645 313dec20a19076cea0be3694adf390f6 388 SUPERFAMILY SSF53067 83 203 2.99E-7 T 14-10-2018 MB46_05645 313dec20a19076cea0be3694adf390f6 388 SUPERFAMILY SSF53067 208 382 2.0E-39 T 14-10-2018 MB46_05645 313dec20a19076cea0be3694adf390f6 388 SUPERFAMILY SSF46785 12 76 6.52E-9 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_05645 313dec20a19076cea0be3694adf390f6 388 Gene3D G3DSA:1.10.10.10 3 82 6.1E-12 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_06580 506f7843be1333bf3466885d9b9cc671 215 Pfam PF12682 Flavodoxin 67 194 1.3E-18 T 14-10-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 MB46_06580 506f7843be1333bf3466885d9b9cc671 215 SUPERFAMILY SSF52218 46 183 4.35E-13 T 14-10-2018 IPR029039 Flavoprotein-like superfamily MB46_06580 506f7843be1333bf3466885d9b9cc671 215 Gene3D G3DSA:3.40.50.360 32 210 2.0E-41 T 14-10-2018 IPR029039 Flavoprotein-like superfamily MB46_01840 739dec32b5e8310b50b5b4dde943036f 428 Gene3D G3DSA:3.90.1150.10 16 401 1.7E-171 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MB46_01840 739dec32b5e8310b50b5b4dde943036f 428 Gene3D G3DSA:3.40.640.10 43 293 1.7E-171 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MB46_01840 739dec32b5e8310b50b5b4dde943036f 428 Pfam PF00464 Serine hydroxymethyltransferase 14 395 4.5E-158 T 14-10-2018 IPR039429 Serine hydroxymethyltransferase-like domain KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 MB46_01840 739dec32b5e8310b50b5b4dde943036f 428 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 228 244 - T 14-10-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 MB46_01840 739dec32b5e8310b50b5b4dde943036f 428 PIRSF PIRSF000412 4 420 1.0E-153 T 14-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 MB46_01840 739dec32b5e8310b50b5b4dde943036f 428 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 13 423 49.704 T 14-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 MB46_01840 739dec32b5e8310b50b5b4dde943036f 428 SUPERFAMILY SSF53383 7 423 6.95E-168 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MB46_02900 81606cb34117605111ac640f76057c55 359 SMART SM00044 157 331 0.0012 T 14-10-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 MB46_02900 81606cb34117605111ac640f76057c55 359 Pfam PF16701 Adenylate cyclase regulatory domain 25 155 1.3E-6 T 14-10-2018 IPR032026 Adenylate cyclase regulatory domain MB46_02900 81606cb34117605111ac640f76057c55 359 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 195 344 2.4E-11 T 14-10-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 MB46_02900 81606cb34117605111ac640f76057c55 359 Gene3D G3DSA:3.30.70.1230 177 347 7.6E-40 T 14-10-2018 IPR029787 Nucleotide cyclase MB46_02900 81606cb34117605111ac640f76057c55 359 SUPERFAMILY SSF55073 193 343 2.51E-33 T 14-10-2018 IPR029787 Nucleotide cyclase MB46_01940 5e13dae7e064bc872aa3e408b5cf1791 401 Pfam PF01546 Peptidase family M20/M25/M40 80 392 4.3E-31 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 MB46_01940 5e13dae7e064bc872aa3e408b5cf1791 401 Gene3D G3DSA:3.30.70.360 191 305 1.6E-112 T 14-10-2018 MB46_01940 5e13dae7e064bc872aa3e408b5cf1791 401 PIRSF PIRSF005962 16 399 9.1E-98 T 14-10-2018 IPR017439 Amidohydrolase GO:0016787 MB46_01940 5e13dae7e064bc872aa3e408b5cf1791 401 SUPERFAMILY SSF55031 192 309 1.45E-22 T 14-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain MB46_01940 5e13dae7e064bc872aa3e408b5cf1791 401 Gene3D G3DSA:3.40.630.10 25 381 1.6E-112 T 14-10-2018 MB46_01940 5e13dae7e064bc872aa3e408b5cf1791 401 SUPERFAMILY SSF53187 15 396 4.63E-73 T 14-10-2018 MB46_01940 5e13dae7e064bc872aa3e408b5cf1791 401 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 26 384 6.3E-101 T 14-10-2018 IPR017439 Amidohydrolase GO:0016787 MB46_06010 db26f1ec0e9b6264dad1a45b2ff79601 443 Gene3D G3DSA:3.40.190.10 158 432 2.8E-117 T 14-10-2018 MB46_06010 db26f1ec0e9b6264dad1a45b2ff79601 443 SUPERFAMILY SSF53850 26 441 1.37E-68 T 14-10-2018 MB46_06010 db26f1ec0e9b6264dad1a45b2ff79601 443 Gene3D G3DSA:3.40.190.10 72 402 2.8E-117 T 14-10-2018 MB46_06010 db26f1ec0e9b6264dad1a45b2ff79601 443 Pfam PF01547 Bacterial extracellular solute-binding protein 53 349 2.3E-31 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein MB46_10815 a273595e67da6519ac3eea0e11ff8c96 67 Gene3D G3DSA:2.40.50.140 2 67 3.2E-29 T 14-10-2018 MB46_10815 a273595e67da6519ac3eea0e11ff8c96 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 14-10-2018 IPR019844 Cold-shock conserved site MB46_10815 a273595e67da6519ac3eea0e11ff8c96 67 PIRSF PIRSF002599 1 67 1.5E-24 T 14-10-2018 IPR012156 Cold shock, CspA GO:0003676 MB46_10815 a273595e67da6519ac3eea0e11ff8c96 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 66 1.1E-30 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MB46_10815 a273595e67da6519ac3eea0e11ff8c96 67 PRINTS PR00050 Cold shock protein signature 40 58 1.3E-16 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MB46_10815 a273595e67da6519ac3eea0e11ff8c96 67 PRINTS PR00050 Cold shock protein signature 25 34 1.3E-16 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MB46_10815 a273595e67da6519ac3eea0e11ff8c96 67 PRINTS PR00050 Cold shock protein signature 4 19 1.3E-16 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MB46_10815 a273595e67da6519ac3eea0e11ff8c96 67 SMART SM00357 3 67 2.0E-29 T 14-10-2018 IPR011129 Cold shock domain GO:0003676 MB46_10815 a273595e67da6519ac3eea0e11ff8c96 67 SUPERFAMILY SSF50249 1 66 1.26E-24 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold MB46_16430 04c79650b01ad6008dc16345562e90e6 641 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 545 561 - T 14-10-2018 IPR002178 PTS EIIA type-2 domain MB46_16430 04c79650b01ad6008dc16345562e90e6 641 TIGRFAM TIGR00851 mtlA: PTS system, mannitol-specific IIC component 17 346 9.3E-150 T 14-10-2018 IPR004718 Phosphotransferase system, mannitol-specific enzyme IIC GO:0008982|GO:0009401|GO:0016021 KEGG: 00051+2.7.1.197 MB46_16430 04c79650b01ad6008dc16345562e90e6 641 SUPERFAMILY SSF52794 386 470 8.89E-22 T 14-10-2018 IPR036095 PTS system IIB component-like superfamily GO:0008982|GO:0009401 MB46_16430 04c79650b01ad6008dc16345562e90e6 641 Pfam PF02378 Phosphotransferase system, EIIC 26 284 8.6E-15 T 14-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 MB46_16430 04c79650b01ad6008dc16345562e90e6 641 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 501 636 9.8E-30 T 14-10-2018 IPR002178 PTS EIIA type-2 domain MB46_16430 04c79650b01ad6008dc16345562e90e6 641 Gene3D G3DSA:3.40.930.10 500 638 2.6E-35 T 14-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 MB46_16430 04c79650b01ad6008dc16345562e90e6 641 Gene3D G3DSA:3.40.50.2300 378 476 3.2E-31 T 14-10-2018 MB46_16430 04c79650b01ad6008dc16345562e90e6 641 SUPERFAMILY SSF55804 502 637 8.63E-34 T 14-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 MB46_16430 04c79650b01ad6008dc16345562e90e6 641 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 387 470 9.1E-11 T 14-10-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 MB46_04270 4ed4c4482ffc7f6e90c0c629bd4b223b 568 Hamap MF_01227 CTP synthase [pyrG]. 22 560 49.382 T 14-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 MB46_04270 4ed4c4482ffc7f6e90c0c629bd4b223b 568 SUPERFAMILY SSF52317 311 560 7.25E-73 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like MB46_04270 4ed4c4482ffc7f6e90c0c629bd4b223b 568 Pfam PF00117 Glutamine amidotransferase class-I 323 554 3.6E-47 T 14-10-2018 IPR017926 Glutamine amidotransferase MB46_04270 4ed4c4482ffc7f6e90c0c629bd4b223b 568 Gene3D G3DSA:3.40.50.300 14 307 1.0E-128 T 14-10-2018 MB46_04270 4ed4c4482ffc7f6e90c0c629bd4b223b 568 Pfam PF06418 CTP synthase N-terminus 23 288 2.6E-120 T 14-10-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 MB46_04270 4ed4c4482ffc7f6e90c0c629bd4b223b 568 SUPERFAMILY SSF52540 22 288 3.19E-115 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_04270 4ed4c4482ffc7f6e90c0c629bd4b223b 568 Gene3D G3DSA:3.40.50.880 308 563 7.4E-97 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like MB46_04270 4ed4c4482ffc7f6e90c0c629bd4b223b 568 TIGRFAM TIGR00337 PyrG: CTP synthase 21 555 3.9E-228 T 14-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 MB46_11215 e17f2843df4bb28c4f1e1e3ff9c233c7 202 SUPERFAMILY SSF46785 10 114 5.85E-26 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_11215 e17f2843df4bb28c4f1e1e3ff9c233c7 202 Gene3D G3DSA:1.10.10.10 3 104 1.3E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_11215 e17f2843df4bb28c4f1e1e3ff9c233c7 202 Pfam PF03551 Transcriptional regulator PadR-like family 14 82 7.8E-20 T 14-10-2018 IPR005149 Transcription regulator PadR, N-terminal MB46_00730 8c4daac6f8339019ffca0181dfb28e5c 567 Gene3D G3DSA:3.10.105.10 279 526 1.0E-153 T 14-10-2018 MB46_00730 8c4daac6f8339019ffca0181dfb28e5c 567 Gene3D G3DSA:3.90.76.10 77 181 1.0E-153 T 14-10-2018 MB46_00730 8c4daac6f8339019ffca0181dfb28e5c 567 Gene3D G3DSA:3.40.190.10 58 550 1.0E-153 T 14-10-2018 MB46_00730 8c4daac6f8339019ffca0181dfb28e5c 567 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 89 461 1.6E-65 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain MB46_00730 8c4daac6f8339019ffca0181dfb28e5c 567 SUPERFAMILY SSF53850 54 551 9.42E-94 T 14-10-2018 MB46_00730 8c4daac6f8339019ffca0181dfb28e5c 567 PIRSF PIRSF002741 4 555 8.2E-67 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 MB46_03990 b68f715a7416205a4b951e666ee5f2d7 424 Pfam PF07690 Major Facilitator Superfamily 18 299 3.1E-18 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MB46_03990 b68f715a7416205a4b951e666ee5f2d7 424 SUPERFAMILY SSF103473 17 418 1.83E-37 T 14-10-2018 IPR036259 MFS transporter superfamily MB46_18245 113c5819c42ed8a9aa00345a324e242e 279 SUPERFAMILY SSF161098 7 279 2.15E-69 T 14-10-2018 IPR035906 MetI-like superfamily MB46_18245 113c5819c42ed8a9aa00345a324e242e 279 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 85 273 8.9E-19 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_18245 113c5819c42ed8a9aa00345a324e242e 279 Gene3D G3DSA:1.10.3720.10 2 267 1.0E-61 T 14-10-2018 IPR035906 MetI-like superfamily MB46_02515 fdde0494f8add9838267b6e9afed5546 476 SUPERFAMILY SSF88713 63 292 1.33E-20 T 14-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 MB46_02515 fdde0494f8add9838267b6e9afed5546 476 Gene3D G3DSA:3.20.20.370 63 203 1.1E-22 T 14-10-2018 MB46_02515 fdde0494f8add9838267b6e9afed5546 476 Pfam PF01522 Polysaccharide deacetylase 73 188 4.2E-12 T 14-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 MB46_05305 e9772e5af04cc532450deb49f47fa278 691 PIRSF PIRSF000168 9 688 1.9E-170 T 14-10-2018 IPR012258 Acyl-CoA oxidase GO:0003997|GO:0005777|GO:0006631|GO:0071949 KEGG: 00071+1.3.3.6|KEGG: 00592+1.3.3.6|MetaCyc: PWY-5136|MetaCyc: PWY-6837|MetaCyc: PWY-6920|MetaCyc: PWY-7007|MetaCyc: PWY-7288|MetaCyc: PWY-7291|MetaCyc: PWY-7337|MetaCyc: PWY-7338|MetaCyc: PWY-7340|MetaCyc: PWY-735|MetaCyc: PWY-7574|MetaCyc: PWY-7606|MetaCyc: PWY-7726|MetaCyc: PWY-7854|MetaCyc: PWY-7858|Reactome: R-HSA-9033241 MB46_05305 e9772e5af04cc532450deb49f47fa278 691 Gene3D G3DSA:2.40.110.10 145 282 7.7E-45 T 14-10-2018 MB46_05305 e9772e5af04cc532450deb49f47fa278 691 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 73 140 6.8E-6 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MB46_05305 e9772e5af04cc532450deb49f47fa278 691 Pfam PF01756 Acyl-CoA oxidase 509 650 2.2E-18 T 14-10-2018 IPR002655 Acyl-CoA oxidase, C-terminal GO:0003997|GO:0005777|GO:0006635 KEGG: 00071+1.3.3.6|KEGG: 00592+1.3.3.6|MetaCyc: PWY-5136|MetaCyc: PWY-6837|MetaCyc: PWY-6920|MetaCyc: PWY-7007|MetaCyc: PWY-7288|MetaCyc: PWY-7291|MetaCyc: PWY-7337|MetaCyc: PWY-7338|MetaCyc: PWY-7340|MetaCyc: PWY-735|MetaCyc: PWY-7574|MetaCyc: PWY-7606|MetaCyc: PWY-7726|MetaCyc: PWY-7854|MetaCyc: PWY-7858 MB46_05305 e9772e5af04cc532450deb49f47fa278 691 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 146 256 6.9E-13 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MB46_05305 e9772e5af04cc532450deb49f47fa278 691 Gene3D G3DSA:1.10.540.10 33 140 9.0E-6 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 MB46_05305 e9772e5af04cc532450deb49f47fa278 691 SUPERFAMILY SSF47203 505 650 1.8E-32 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 MB46_05305 e9772e5af04cc532450deb49f47fa278 691 SUPERFAMILY SSF56645 57 269 2.62E-51 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 MB46_05305 e9772e5af04cc532450deb49f47fa278 691 Gene3D G3DSA:1.20.140.10 290 459 1.2E-51 T 14-10-2018 MB46_05305 e9772e5af04cc532450deb49f47fa278 691 Gene3D G3DSA:1.20.140.10 509 639 3.2E-20 T 14-10-2018 MB46_05305 e9772e5af04cc532450deb49f47fa278 691 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 290 451 7.7E-10 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MB46_05305 e9772e5af04cc532450deb49f47fa278 691 SUPERFAMILY SSF47203 286 463 1.37E-50 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 MB46_00520 9ee2fd3ee976a76d780636c01ea721a2 389 Pfam PF00842 Alanine racemase, C-terminal domain 256 366 8.4E-28 T 14-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MB46_00520 9ee2fd3ee976a76d780636c01ea721a2 389 SMART SM01005 255 382 1.2E-32 T 14-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MB46_00520 9ee2fd3ee976a76d780636c01ea721a2 389 Gene3D G3DSA:3.20.20.10 25 242 4.5E-112 T 14-10-2018 IPR029066 PLP-binding barrel MB46_00520 9ee2fd3ee976a76d780636c01ea721a2 389 Gene3D G3DSA:2.40.37.10 19 375 4.5E-112 T 14-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 MB46_00520 9ee2fd3ee976a76d780636c01ea721a2 389 PRINTS PR00992 Alanine racemase signature 309 326 7.5E-29 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MB46_00520 9ee2fd3ee976a76d780636c01ea721a2 389 PRINTS PR00992 Alanine racemase signature 42 58 7.5E-29 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MB46_00520 9ee2fd3ee976a76d780636c01ea721a2 389 PRINTS PR00992 Alanine racemase signature 176 187 7.5E-29 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MB46_00520 9ee2fd3ee976a76d780636c01ea721a2 389 PRINTS PR00992 Alanine racemase signature 288 303 7.5E-29 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MB46_00520 9ee2fd3ee976a76d780636c01ea721a2 389 PRINTS PR00992 Alanine racemase signature 78 96 7.5E-29 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MB46_00520 9ee2fd3ee976a76d780636c01ea721a2 389 PRINTS PR00992 Alanine racemase signature 271 286 7.5E-29 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MB46_00520 9ee2fd3ee976a76d780636c01ea721a2 389 PRINTS PR00992 Alanine racemase signature 219 246 7.5E-29 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MB46_00520 9ee2fd3ee976a76d780636c01ea721a2 389 TIGRFAM TIGR00492 alr: alanine racemase 19 359 1.4E-56 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MB46_00520 9ee2fd3ee976a76d780636c01ea721a2 389 SUPERFAMILY SSF50621 252 376 1.6E-31 T 14-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 MB46_00520 9ee2fd3ee976a76d780636c01ea721a2 389 SUPERFAMILY SSF51419 23 246 4.94E-37 T 14-10-2018 IPR029066 PLP-binding barrel MB46_00520 9ee2fd3ee976a76d780636c01ea721a2 389 Pfam PF01168 Alanine racemase, N-terminal domain 23 245 1.2E-38 T 14-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MB46_00520 9ee2fd3ee976a76d780636c01ea721a2 389 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 47 57 - T 14-10-2018 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MB46_00520 9ee2fd3ee976a76d780636c01ea721a2 389 Hamap MF_01201 Alanine racemase. 16 385 22.206 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MB46_02885 4c6ed9a69d595781ac4b94afedc811c1 527 SUPERFAMILY SSF52096 248 527 9.82E-87 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MB46_02885 4c6ed9a69d595781ac4b94afedc811c1 527 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 100 114 4.5E-5 T 14-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 MB46_02885 4c6ed9a69d595781ac4b94afedc811c1 527 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 134 152 4.5E-5 T 14-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 MB46_02885 4c6ed9a69d595781ac4b94afedc811c1 527 Gene3D G3DSA:3.90.226.10 1 263 2.7E-92 T 14-10-2018 MB46_02885 4c6ed9a69d595781ac4b94afedc811c1 527 Pfam PF01039 Carboxyl transferase domain 33 525 3.1E-191 T 14-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 MB46_02885 4c6ed9a69d595781ac4b94afedc811c1 527 Gene3D G3DSA:3.90.226.10 265 527 5.6E-90 T 14-10-2018 MB46_02885 4c6ed9a69d595781ac4b94afedc811c1 527 SUPERFAMILY SSF52096 10 259 3.13E-77 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MB46_12715 f27e3ca4ffc61b41893f9f7b99878083 171 Pfam PF13412 Winged helix-turn-helix DNA-binding 22 69 2.6E-12 T 14-10-2018 MB46_12715 f27e3ca4ffc61b41893f9f7b99878083 171 SUPERFAMILY SSF54909 84 164 8.04E-15 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel MB46_12715 f27e3ca4ffc61b41893f9f7b99878083 171 Pfam PF01037 Lrp/AsnC ligand binding domain 88 161 3.6E-15 T 14-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain MB46_12715 f27e3ca4ffc61b41893f9f7b99878083 171 SMART SM00344 22 131 3.5E-28 T 14-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 MB46_12715 f27e3ca4ffc61b41893f9f7b99878083 171 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 38 49 8.1E-12 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 MB46_12715 f27e3ca4ffc61b41893f9f7b99878083 171 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 22 38 8.1E-12 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 MB46_12715 f27e3ca4ffc61b41893f9f7b99878083 171 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 49 68 8.1E-12 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 MB46_12715 f27e3ca4ffc61b41893f9f7b99878083 171 Gene3D G3DSA:3.30.70.920 76 159 3.2E-19 T 14-10-2018 MB46_12715 f27e3ca4ffc61b41893f9f7b99878083 171 SUPERFAMILY SSF46785 21 81 5.29E-13 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_12715 f27e3ca4ffc61b41893f9f7b99878083 171 Gene3D G3DSA:1.10.10.10 14 75 1.1E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_18195 cb88795b3741cd767ccde49f304c822f 126 Gene3D G3DSA:3.10.290.10 5 100 2.2E-28 T 14-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 MB46_18195 cb88795b3741cd767ccde49f304c822f 126 SUPERFAMILY SSF55174 10 93 9.55E-21 T 14-10-2018 MB46_18195 cb88795b3741cd767ccde49f304c822f 126 SMART SM00363 11 75 4.4E-5 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MB46_18195 cb88795b3741cd767ccde49f304c822f 126 Pfam PF01479 S4 domain 11 57 4.3E-8 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MB46_18195 cb88795b3741cd767ccde49f304c822f 126 PIRSF PIRSF016821 8 126 2.6E-43 T 14-10-2018 IPR025708 Heat shock protein 15 GO:0003677|GO:0003727|GO:0034605|GO:0043023 MB46_16215 c50053f714eeae50269112a4bf01c824 489 SUPERFAMILY SSF56601 138 488 2.73E-75 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like MB46_16215 c50053f714eeae50269112a4bf01c824 489 Pfam PF00905 Penicillin binding protein transpeptidase domain 156 485 5.1E-60 T 14-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 MB46_16215 c50053f714eeae50269112a4bf01c824 489 Gene3D G3DSA:3.40.710.10 137 482 1.9E-123 T 14-10-2018 MB46_16215 c50053f714eeae50269112a4bf01c824 489 Gene3D G3DSA:3.90.1310.10 57 384 1.9E-123 T 14-10-2018 MB46_04660 bd7db8b9e8a7b2fbb79f972159c2479a 580 SMART SM00917 439 574 1.7E-34 T 14-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 MB46_04660 bd7db8b9e8a7b2fbb79f972159c2479a 580 SUPERFAMILY SSF51569 29 337 2.75E-96 T 14-10-2018 MB46_04660 bd7db8b9e8a7b2fbb79f972159c2479a 580 SUPERFAMILY SSF89000 405 454 4.32E-14 T 14-10-2018 MB46_04660 bd7db8b9e8a7b2fbb79f972159c2479a 580 Hamap MF_00572 2-isopropylmalate synthase [leuA]. 12 575 53.858 T 14-10-2018 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 MB46_04660 bd7db8b9e8a7b2fbb79f972159c2479a 580 Gene3D G3DSA:3.30.160.270 394 573 1.1E-58 T 14-10-2018 MB46_04660 bd7db8b9e8a7b2fbb79f972159c2479a 580 SUPERFAMILY SSF110921 471 573 7.45E-34 T 14-10-2018 IPR036230 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain superfamily KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 MB46_04660 bd7db8b9e8a7b2fbb79f972159c2479a 580 TIGRFAM TIGR00970 leuA_yeast: 2-isopropylmalate synthase 11 575 7.6E-254 T 14-10-2018 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 MB46_04660 bd7db8b9e8a7b2fbb79f972159c2479a 580 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 47 63 - T 14-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 MB46_04660 bd7db8b9e8a7b2fbb79f972159c2479a 580 Pfam PF08502 LeuA allosteric (dimerisation) domain 439 573 1.3E-27 T 14-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 MB46_04660 bd7db8b9e8a7b2fbb79f972159c2479a 580 Gene3D G3DSA:3.20.20.70 19 393 4.5E-153 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MB46_04660 bd7db8b9e8a7b2fbb79f972159c2479a 580 Pfam PF00682 HMGL-like 40 320 8.3E-75 T 14-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 MB46_04660 bd7db8b9e8a7b2fbb79f972159c2479a 580 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 250 263 - T 14-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 MB46_15385 3347dadef7edcf24ceed74cd640e5baa 215 SUPERFAMILY SSF101473 5 209 6.15E-54 T 14-10-2018 IPR036117 DhaL domain superfamily GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 MB46_15385 3347dadef7edcf24ceed74cd640e5baa 215 SMART SM01120 35 209 7.5E-76 T 14-10-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 MB46_15385 3347dadef7edcf24ceed74cd640e5baa 215 TIGRFAM TIGR02365 dha_L_ycgS: dihydroxyacetone kinase, L subunit 12 208 5.3E-71 T 14-10-2018 IPR012737 Dihydroxyacetone kinase, subunit L GO:0016772 KEGG: 00561+2.7.1.121 MB46_15385 3347dadef7edcf24ceed74cd640e5baa 215 Pfam PF02734 DAK2 domain 36 208 4.7E-54 T 14-10-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 MB46_15385 3347dadef7edcf24ceed74cd640e5baa 215 Gene3D G3DSA:1.25.40.340 4 212 2.6E-63 T 14-10-2018 IPR036117 DhaL domain superfamily GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 MB46_16110 553afee38d85639f4222d1e8ca11bcca 295 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 162 271 8.4E-25 T 14-10-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 MB46_16110 553afee38d85639f4222d1e8ca11bcca 295 TIGRFAM TIGR00872 gnd_rel: 6-phosphogluconate dehydrogenase (decarboxylating) 2 293 6.4E-97 T 14-10-2018 IPR004849 6-phosphogluconate dehydrogenase, YqeC-type GO:0055114 MB46_16110 553afee38d85639f4222d1e8ca11bcca 295 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 3 142 4.1E-33 T 14-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 MB46_16110 553afee38d85639f4222d1e8ca11bcca 295 SUPERFAMILY SSF51735 2 148 2.28E-39 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_16110 553afee38d85639f4222d1e8ca11bcca 295 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 50 79 2.3E-35 T 14-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 MB46_16110 553afee38d85639f4222d1e8ca11bcca 295 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 226 253 2.3E-35 T 14-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 MB46_16110 553afee38d85639f4222d1e8ca11bcca 295 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 151 179 2.3E-35 T 14-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 MB46_16110 553afee38d85639f4222d1e8ca11bcca 295 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 1 15 2.3E-35 T 14-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 MB46_16110 553afee38d85639f4222d1e8ca11bcca 295 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 103 128 2.3E-35 T 14-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 MB46_16110 553afee38d85639f4222d1e8ca11bcca 295 Gene3D G3DSA:3.40.50.720 1 161 2.4E-39 T 14-10-2018 MB46_16110 553afee38d85639f4222d1e8ca11bcca 295 ProSitePatterns PS00461 6-phosphogluconate dehydrogenase signature. 230 242 - T 14-10-2018 IPR006184 6-phosphogluconate-binding site GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 MB46_16110 553afee38d85639f4222d1e8ca11bcca 295 Gene3D G3DSA:1.10.1040.10 162 292 1.3E-48 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MB46_16110 553afee38d85639f4222d1e8ca11bcca 295 SUPERFAMILY SSF48179 160 290 9.52E-40 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MB46_16110 553afee38d85639f4222d1e8ca11bcca 295 SMART SM01350 162 290 1.2E-5 T 14-10-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 MB46_11205 49c7c5481b79ef1d7a09a472dc09049e 199 Gene3D G3DSA:3.40.50.1110 2 195 3.1E-44 T 14-10-2018 IPR036514 SGNH hydrolase superfamily MB46_11205 49c7c5481b79ef1d7a09a472dc09049e 199 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 10 177 5.2E-12 T 14-10-2018 IPR013830 SGNH hydrolase-type esterase domain MB46_11205 49c7c5481b79ef1d7a09a472dc09049e 199 SUPERFAMILY SSF52266 3 185 3.66E-28 T 14-10-2018 MB46_06835 cba3d3554013f8c7a638eb7028e4ac05 239 Gene3D G3DSA:1.20.120.450 7 163 3.1E-51 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes MB46_06835 cba3d3554013f8c7a638eb7028e4ac05 239 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 21 156 9.7E-27 T 14-10-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 MB46_06835 cba3d3554013f8c7a638eb7028e4ac05 239 Gene3D G3DSA:3.30.1050.20 164 239 2.1E-20 T 14-10-2018 MB46_06835 cba3d3554013f8c7a638eb7028e4ac05 239 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 20 226 2.0E-39 T 14-10-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type MB46_06835 cba3d3554013f8c7a638eb7028e4ac05 239 SUPERFAMILY SSF55718 165 238 3.88E-12 T 14-10-2018 IPR036527 SCP2 sterol-binding domain superfamily MB46_06835 cba3d3554013f8c7a638eb7028e4ac05 239 SUPERFAMILY SSF109854 8 162 4.03E-43 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes MB46_03835 c2db0b70a627f3f49a338f3bcae8226e 362 SMART SM00729 32 234 0.0032 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 MB46_03835 c2db0b70a627f3f49a338f3bcae8226e 362 SUPERFAMILY SSF102114 23 302 1.02E-66 T 14-10-2018 MB46_03835 c2db0b70a627f3f49a338f3bcae8226e 362 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 38 49 - T 14-10-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MB46_03835 c2db0b70a627f3f49a338f3bcae8226e 362 Pfam PF04055 Radical SAM superfamily 38 198 3.7E-31 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MB46_03835 c2db0b70a627f3f49a338f3bcae8226e 362 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 23 362 2.8E-103 T 14-10-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MB46_03835 c2db0b70a627f3f49a338f3bcae8226e 362 Hamap MF_01225_B GTP 3',8-cyclase [moaA]. 23 362 38.439 T 14-10-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MB46_03835 c2db0b70a627f3f49a338f3bcae8226e 362 Pfam PF06463 Molybdenum Cofactor Synthesis C 204 339 3.1E-30 T 14-10-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MB46_03835 c2db0b70a627f3f49a338f3bcae8226e 362 Gene3D G3DSA:3.20.20.70 20 362 7.3E-82 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MB46_03835 c2db0b70a627f3f49a338f3bcae8226e 362 Pfam PF13394 4Fe-4S single cluster domain 39 122 7.6E-8 T 14-10-2018 MB46_14375 6266857f68b0ca934db4338f0de3e269 150 SUPERFAMILY SSF54909 71 145 1.05E-16 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel MB46_14375 6266857f68b0ca934db4338f0de3e269 150 Gene3D G3DSA:1.10.10.10 1 62 2.8E-16 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_14375 6266857f68b0ca934db4338f0de3e269 150 Pfam PF13404 AsnC-type helix-turn-helix domain 9 49 1.5E-12 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 MB46_14375 6266857f68b0ca934db4338f0de3e269 150 Pfam PF01037 Lrp/AsnC ligand binding domain 75 145 6.7E-15 T 14-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain MB46_14375 6266857f68b0ca934db4338f0de3e269 150 Gene3D G3DSA:3.30.70.920 63 150 2.3E-20 T 14-10-2018 MB46_14375 6266857f68b0ca934db4338f0de3e269 150 SMART SM00344 9 115 3.4E-28 T 14-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 MB46_14375 6266857f68b0ca934db4338f0de3e269 150 SUPERFAMILY SSF46785 8 68 8.24E-13 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_14375 6266857f68b0ca934db4338f0de3e269 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 25 36 3.3E-8 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 MB46_14375 6266857f68b0ca934db4338f0de3e269 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 36 55 3.3E-8 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 MB46_14375 6266857f68b0ca934db4338f0de3e269 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 9 25 3.3E-8 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 MB46_09710 b3fa02be85fe33e1299cf1915029643d 272 PIRSF PIRSF039085 14 267 4.7E-115 T 14-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 MB46_09710 b3fa02be85fe33e1299cf1915029643d 272 SUPERFAMILY SSF52540 17 261 1.98E-79 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_09710 b3fa02be85fe33e1299cf1915029643d 272 SMART SM00382 42 239 1.9E-21 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_09710 b3fa02be85fe33e1299cf1915029643d 272 ProSitePatterns PS00211 ABC transporters family signature. 163 177 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_09710 b3fa02be85fe33e1299cf1915029643d 272 Pfam PF00005 ABC transporter 33 191 2.2E-35 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_09710 b3fa02be85fe33e1299cf1915029643d 272 Gene3D G3DSA:3.40.50.300 15 270 1.7E-82 T 14-10-2018 MB46_10645 6510c115ebc66af1199f414b6aa7e761 407 Gene3D G3DSA:1.20.1250.20 216 407 4.9E-11 T 14-10-2018 MB46_10645 6510c115ebc66af1199f414b6aa7e761 407 SUPERFAMILY SSF103473 18 398 5.36E-27 T 14-10-2018 IPR036259 MFS transporter superfamily MB46_10645 6510c115ebc66af1199f414b6aa7e761 407 Gene3D G3DSA:1.20.1250.20 14 203 7.0E-13 T 14-10-2018 MB46_10645 6510c115ebc66af1199f414b6aa7e761 407 Pfam PF07690 Major Facilitator Superfamily 25 351 6.1E-13 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MB46_14155 17b1fe1c533a759b5eb55587d1eb8535 482 Pfam PF07905 Purine catabolism regulatory protein-like family 7 123 1.8E-23 T 14-10-2018 IPR012914 Purine catabolism PurC-like domain MB46_14155 17b1fe1c533a759b5eb55587d1eb8535 482 Pfam PF13556 PucR C-terminal helix-turn-helix domain 417 474 1.4E-21 T 14-10-2018 IPR025736 PucR C-terminal helix-turn-helix domain MB46_14155 17b1fe1c533a759b5eb55587d1eb8535 482 Gene3D G3DSA:1.10.10.2840 355 481 1.7E-23 T 14-10-2018 MB46_10565 59d61d0b8f92de5b0bb2e11ffdb26120 284 Gene3D G3DSA:3.40.50.10490 98 276 2.2E-31 T 14-10-2018 MB46_10565 59d61d0b8f92de5b0bb2e11ffdb26120 284 Pfam PF01418 Helix-turn-helix domain, rpiR family 8 79 2.7E-17 T 14-10-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 MB46_10565 59d61d0b8f92de5b0bb2e11ffdb26120 284 SUPERFAMILY SSF46689 8 79 3.05E-16 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MB46_10565 59d61d0b8f92de5b0bb2e11ffdb26120 284 Gene3D G3DSA:1.10.10.10 3 85 2.1E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_10565 59d61d0b8f92de5b0bb2e11ffdb26120 284 Pfam PF01380 SIS domain 128 235 1.6E-12 T 14-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 MB46_10565 59d61d0b8f92de5b0bb2e11ffdb26120 284 SUPERFAMILY SSF53697 102 265 3.44E-28 T 14-10-2018 MB46_11165 a4043a0122d8dc1d472753dfe50988cb 616 Gene3D G3DSA:3.40.50.300 326 610 3.3E-76 T 14-10-2018 MB46_11165 a4043a0122d8dc1d472753dfe50988cb 616 ProSitePatterns PS00211 ABC transporters family signature. 485 499 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_11165 a4043a0122d8dc1d472753dfe50988cb 616 SUPERFAMILY SSF161098 87 274 7.98E-23 T 14-10-2018 IPR035906 MetI-like superfamily MB46_11165 a4043a0122d8dc1d472753dfe50988cb 616 SUPERFAMILY SSF52540 329 584 9.03E-58 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_11165 a4043a0122d8dc1d472753dfe50988cb 616 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 290 3.1E-17 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_11165 a4043a0122d8dc1d472753dfe50988cb 616 Pfam PF00005 ABC transporter 350 512 2.1E-24 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_11165 a4043a0122d8dc1d472753dfe50988cb 616 Gene3D G3DSA:1.10.3720.10 82 293 2.4E-19 T 14-10-2018 IPR035906 MetI-like superfamily MB46_11165 a4043a0122d8dc1d472753dfe50988cb 616 SMART SM00382 358 562 3.3E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_11165 a4043a0122d8dc1d472753dfe50988cb 616 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 25 66 1.8E-6 T 14-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain MB46_04935 5e5715d68ff6c75d0ffe7a93505f6275 152 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 35 147 2.3E-26 T 14-10-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 MB46_04935 5e5715d68ff6c75d0ffe7a93505f6275 152 Gene3D G3DSA:3.10.129.10 24 152 2.6E-40 T 14-10-2018 MB46_04935 5e5715d68ff6c75d0ffe7a93505f6275 152 Pfam PF03061 Thioesterase superfamily 65 138 2.1E-11 T 14-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 MB46_04935 5e5715d68ff6c75d0ffe7a93505f6275 152 SUPERFAMILY SSF54637 35 151 1.88E-22 T 14-10-2018 IPR029069 HotDog domain superfamily MB46_05225 9f00b30fab7f67d5a228e7d4751fb528 307 Gene3D G3DSA:3.40.50.1000 52 302 6.7E-67 T 14-10-2018 IPR023214 HAD superfamily MB46_05225 9f00b30fab7f67d5a228e7d4751fb528 307 Pfam PF12710 haloacid dehalogenase-like hydrolase 100 267 9.8E-24 T 14-10-2018 MB46_05225 9f00b30fab7f67d5a228e7d4751fb528 307 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 100 269 2.2E-31 T 14-10-2018 MB46_05225 9f00b30fab7f67d5a228e7d4751fb528 307 TIGRFAM TIGR00338 serB: phosphoserine phosphatase SerB 94 296 2.9E-66 T 14-10-2018 MB46_05225 9f00b30fab7f67d5a228e7d4751fb528 307 SUPERFAMILY SSF56784 98 301 5.89E-43 T 14-10-2018 IPR036412 HAD-like superfamily MB46_16875 571aa29643cb7764d5922c130a8c7f52 138 SUPERFAMILY SSF50692 1 116 1.86E-47 T 14-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily MB46_16875 571aa29643cb7764d5922c130a8c7f52 138 Pfam PF02261 Aspartate decarboxylase 1 114 4.0E-49 T 14-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 MB46_16875 571aa29643cb7764d5922c130a8c7f52 138 Hamap MF_00446 Aspartate 1-decarboxylase [panD]. 1 127 70.993 T 14-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 MB46_16875 571aa29643cb7764d5922c130a8c7f52 138 PIRSF PIRSF006246 1 130 1.5E-49 T 14-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 MB46_16875 571aa29643cb7764d5922c130a8c7f52 138 Gene3D G3DSA:2.40.40.20 1 124 1.0E-50 T 14-10-2018 MB46_16875 571aa29643cb7764d5922c130a8c7f52 138 ProDom PD009294 ASPARTATE 1-DECARBOXYLASE DECARBOXYLASE CHAIN LYASE ALPHA ALPHA- CONTAINS: PRECURSOR BETA 5 114 1.0E-35 T 14-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 MB46_16875 571aa29643cb7764d5922c130a8c7f52 138 TIGRFAM TIGR00223 panD: aspartate 1-decarboxylase 1 122 1.6E-48 T 14-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 MB46_05675 f9596494b630ab2dbcbec2a403a2088c 388 Pfam PF14606 GDSL-like Lipase/Acylhydrolase family 175 275 2.0E-16 T 14-10-2018 IPR013830 SGNH hydrolase-type esterase domain MB46_05675 f9596494b630ab2dbcbec2a403a2088c 388 Gene3D G3DSA:2.60.120.260 7 163 3.8E-38 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily MB46_05675 f9596494b630ab2dbcbec2a403a2088c 388 SUPERFAMILY SSF52266 167 378 7.61E-23 T 14-10-2018 MB46_05675 f9596494b630ab2dbcbec2a403a2088c 388 Gene3D G3DSA:3.40.50.1110 169 384 1.1E-66 T 14-10-2018 IPR036514 SGNH hydrolase superfamily MB46_04360 b3b0f46c8a1674b895c633e5e55ee955 109 Gene3D G3DSA:2.60.120.10 9 108 2.9E-17 T 14-10-2018 IPR014710 RmlC-like jelly roll fold MB46_04360 b3b0f46c8a1674b895c633e5e55ee955 109 SUPERFAMILY SSF51182 24 106 7.64E-10 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily MB46_09915 996efa31a52d1a37ec9fbaddfc2964bc 377 Pfam PF07478 D-ala D-ala ligase C-terminus 159 367 1.1E-65 T 14-10-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MB46_09915 996efa31a52d1a37ec9fbaddfc2964bc 377 Gene3D G3DSA:3.30.1490.20 166 237 3.6E-73 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 MB46_09915 996efa31a52d1a37ec9fbaddfc2964bc 377 SUPERFAMILY SSF52440 12 150 1.63E-34 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily MB46_09915 996efa31a52d1a37ec9fbaddfc2964bc 377 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 13 369 6.1E-102 T 14-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MB46_09915 996efa31a52d1a37ec9fbaddfc2964bc 377 Gene3D G3DSA:3.40.50.20 7 139 1.6E-36 T 14-10-2018 MB46_09915 996efa31a52d1a37ec9fbaddfc2964bc 377 Pfam PF01820 D-ala D-ala ligase N-terminus 13 140 5.1E-29 T 14-10-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MB46_09915 996efa31a52d1a37ec9fbaddfc2964bc 377 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 118 129 - T 14-10-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MB46_09915 996efa31a52d1a37ec9fbaddfc2964bc 377 Gene3D G3DSA:3.30.470.20 140 369 3.6E-73 T 14-10-2018 MB46_09915 996efa31a52d1a37ec9fbaddfc2964bc 377 PIRSF PIRSF039102 9 375 1.6E-104 T 14-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MB46_09915 996efa31a52d1a37ec9fbaddfc2964bc 377 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 12 370 39.668 T 14-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MB46_09915 996efa31a52d1a37ec9fbaddfc2964bc 377 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 312 340 - T 14-10-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MB46_09915 996efa31a52d1a37ec9fbaddfc2964bc 377 SUPERFAMILY SSF56059 151 372 1.64E-53 T 14-10-2018 MB46_19715 7b067a34807819287e9fef36c077523e 210 Pfam PF00239 Resolvase, N terminal domain 5 143 2.9E-37 T 14-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 MB46_19715 7b067a34807819287e9fef36c077523e 210 SUPERFAMILY SSF53041 4 143 1.83E-36 T 14-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 MB46_19715 7b067a34807819287e9fef36c077523e 210 SMART SM00857 4 144 1.7E-45 T 14-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 MB46_19715 7b067a34807819287e9fef36c077523e 210 Gene3D G3DSA:3.40.50.1390 4 132 5.0E-37 T 14-10-2018 MB46_19715 7b067a34807819287e9fef36c077523e 210 SUPERFAMILY SSF46689 147 187 6.4E-9 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MB46_19715 7b067a34807819287e9fef36c077523e 210 Pfam PF02796 Helix-turn-helix domain of resolvase 147 186 3.5E-7 T 14-10-2018 IPR006120 Resolvase, HTH domain GO:0000150|GO:0003677|GO:0006310 MB46_19715 7b067a34807819287e9fef36c077523e 210 ProSitePatterns PS00397 Site-specific recombinases active site. 7 15 - T 14-10-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 MB46_08675 ffe28b4063db7d75b14275b044e17564 195 Gene3D G3DSA:3.30.420.10 1 160 8.8E-47 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 MB46_08675 ffe28b4063db7d75b14275b044e17564 195 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 140 152 2.1E-36 T 14-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 MB46_08675 ffe28b4063db7d75b14275b044e17564 195 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 84 100 2.1E-36 T 14-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 MB46_08675 ffe28b4063db7d75b14275b044e17564 195 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 108 127 2.1E-36 T 14-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 MB46_08675 ffe28b4063db7d75b14275b044e17564 195 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 4 17 2.1E-36 T 14-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 MB46_08675 ffe28b4063db7d75b14275b044e17564 195 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 62 78 2.1E-36 T 14-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 MB46_08675 ffe28b4063db7d75b14275b044e17564 195 SUPERFAMILY SSF53098 1 158 4.93E-42 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily MB46_08675 ffe28b4063db7d75b14275b044e17564 195 Hamap MF_00034 Crossover junction endodeoxyribonuclease RuvC [ruvC]. 1 155 43.412 T 14-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 MB46_08675 ffe28b4063db7d75b14275b044e17564 195 Pfam PF02075 Crossover junction endodeoxyribonuclease RuvC 3 152 1.4E-51 T 14-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 MB46_08675 ffe28b4063db7d75b14275b044e17564 195 TIGRFAM TIGR00228 ruvC: crossover junction endodeoxyribonuclease RuvC 3 159 1.8E-36 T 14-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 MB46_13285 03e5948afc488d311a2f82c9918de818 133 Pfam PF00411 Ribosomal protein S11 23 132 8.9E-47 T 14-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 MB46_13285 03e5948afc488d311a2f82c9918de818 133 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 4 133 33.14 T 14-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 MB46_13285 03e5948afc488d311a2f82c9918de818 133 ProSitePatterns PS00054 Ribosomal protein S11 signature. 101 123 - T 14-10-2018 IPR018102 Ribosomal S11, conserved site MB46_13285 03e5948afc488d311a2f82c9918de818 133 Gene3D G3DSA:3.30.420.80 1 133 9.3E-55 T 14-10-2018 IPR036967 Ribosomal protein S11 superfamily GO:0003735|GO:0005840|GO:0006412 MB46_13285 03e5948afc488d311a2f82c9918de818 133 SUPERFAMILY SSF53137 18 133 2.4E-48 T 14-10-2018 MB46_13285 03e5948afc488d311a2f82c9918de818 133 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 14 130 3.0E-57 T 14-10-2018 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 MB46_13285 03e5948afc488d311a2f82c9918de818 133 PIRSF PIRSF002131 3 133 8.8E-54 T 14-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 MB46_06185 5b1e37f8fe51776b4b91247803ac6de2 529 Gene3D G3DSA:1.20.1530.20 3 410 2.5E-10 T 14-10-2018 IPR038770 Sodium/solute symporter superfamily MB46_06185 5b1e37f8fe51776b4b91247803ac6de2 529 Pfam PF00999 Sodium/hydrogen exchanger family 8 403 2.9E-58 T 14-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 MB46_06185 5b1e37f8fe51776b4b91247803ac6de2 529 TIGRFAM TIGR00831 a_cpa1: Na+/H+ antiporter 8 523 6.4E-124 T 14-10-2018 IPR004705 Cation/H+ exchanger, CPA1 family, bacteria GO:0006812|GO:0015299|GO:0016021 MB46_08605 b5b37cc9bdf1cb38b48213d23ea61216 263 Gene3D G3DSA:3.40.50.300 1 249 5.0E-69 T 14-10-2018 MB46_08605 b5b37cc9bdf1cb38b48213d23ea61216 263 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_08605 b5b37cc9bdf1cb38b48213d23ea61216 263 SUPERFAMILY SSF52540 2 233 6.1E-62 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_08605 b5b37cc9bdf1cb38b48213d23ea61216 263 Pfam PF00005 ABC transporter 17 166 1.2E-29 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_08605 b5b37cc9bdf1cb38b48213d23ea61216 263 SMART SM00382 26 214 1.5E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_05500 a38735aa671ee573f511ef9fd6d05531 213 SUPERFAMILY SSF56420 25 186 1.09E-44 T 14-10-2018 IPR036821 Peptide deformylase superfamily MB46_05500 a38735aa671ee573f511ef9fd6d05531 213 PRINTS PR01576 Peptide deformylase signature 157 186 1.7E-27 T 14-10-2018 IPR023635 Peptide deformylase MB46_05500 a38735aa671ee573f511ef9fd6d05531 213 PRINTS PR01576 Peptide deformylase signature 57 86 1.7E-27 T 14-10-2018 IPR023635 Peptide deformylase MB46_05500 a38735aa671ee573f511ef9fd6d05531 213 PRINTS PR01576 Peptide deformylase signature 138 156 1.7E-27 T 14-10-2018 IPR023635 Peptide deformylase MB46_05500 a38735aa671ee573f511ef9fd6d05531 213 PRINTS PR01576 Peptide deformylase signature 126 137 1.7E-27 T 14-10-2018 IPR023635 Peptide deformylase MB46_05500 a38735aa671ee573f511ef9fd6d05531 213 Pfam PF01327 Polypeptide deformylase 27 185 2.0E-41 T 14-10-2018 IPR023635 Peptide deformylase MB46_05500 a38735aa671ee573f511ef9fd6d05531 213 Hamap MF_00163 Peptide deformylase [def]. 24 192 23.505 T 14-10-2018 IPR023635 Peptide deformylase MB46_05500 a38735aa671ee573f511ef9fd6d05531 213 PIRSF PIRSF004749 4 206 6.4E-45 T 14-10-2018 IPR023635 Peptide deformylase MB46_05500 a38735aa671ee573f511ef9fd6d05531 213 Gene3D G3DSA:3.90.45.10 24 208 1.7E-51 T 14-10-2018 IPR036821 Peptide deformylase superfamily MB46_11875 68d1a47d0a92236a0f49f9f03d535eb3 349 SUPERFAMILY SSF52096 1 320 3.09E-65 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MB46_11875 68d1a47d0a92236a0f49f9f03d535eb3 349 Pfam PF16113 Enoyl-CoA hydratase/isomerase 15 334 2.0E-116 T 14-10-2018 IPR032259 Enoyl-CoA hydratase/isomerase, HIBYL-CoA-H type GO:0003860 Reactome: R-HSA-70895 MB46_11875 68d1a47d0a92236a0f49f9f03d535eb3 349 Gene3D G3DSA:3.90.226.40 1 344 6.7E-124 T 14-10-2018 MB46_09765 45fb97163dc3062577fb64c8e931c146 67 Pfam PF01783 Ribosomal L32p protein family 2 64 1.1E-12 T 14-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_09765 45fb97163dc3062577fb64c8e931c146 67 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 2 65 11.851 T 14-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_09765 45fb97163dc3062577fb64c8e931c146 67 SUPERFAMILY SSF57829 2 44 3.72E-9 T 14-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 MB46_09765 45fb97163dc3062577fb64c8e931c146 67 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 44 5.6E-11 T 14-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_13870 6ea83bfb737d727929de20be9f7a8ec4 388 SUPERFAMILY SSF51338 1 374 9.3E-24 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 MB46_13870 6ea83bfb737d727929de20be9f7a8ec4 388 Gene3D G3DSA:3.20.20.140 53 335 8.3E-125 T 14-10-2018 MB46_13870 6ea83bfb737d727929de20be9f7a8ec4 388 Pfam PF01979 Amidohydrolase family 50 371 5.6E-22 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 MB46_13870 6ea83bfb737d727929de20be9f7a8ec4 388 SUPERFAMILY SSF51556 52 339 4.76E-44 T 14-10-2018 IPR032466 Metal-dependent hydrolase MB46_13870 6ea83bfb737d727929de20be9f7a8ec4 388 Gene3D G3DSA:2.30.40.10 5 369 8.3E-125 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 MB46_01215 1f390cd9cdceeaaa39babe5cd460a96a 140 Gene3D G3DSA:3.40.50.2300 8 138 9.8E-50 T 14-10-2018 MB46_01215 1f390cd9cdceeaaa39babe5cd460a96a 140 SMART SM00226 10 135 1.0E-44 T 14-10-2018 IPR023485 Phosphotyrosine protein phosphatase I MB46_01215 1f390cd9cdceeaaa39babe5cd460a96a 140 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 12 132 8.4E-23 T 14-10-2018 IPR023485 Phosphotyrosine protein phosphatase I MB46_01215 1f390cd9cdceeaaa39babe5cd460a96a 140 SUPERFAMILY SSF52788 9 133 6.41E-35 T 14-10-2018 IPR036196 Phosphotyrosine protein phosphatase I superfamily MB46_15235 27ef482bdec8a22d3e06970153237160 431 Pfam PF04286 Protein of unknown function (DUF445) 66 428 1.3E-107 T 14-10-2018 IPR007383 Protein of unknown function DUF445 MB46_06795 6ec5ba8ea729a013d6826e703def179a 101 SUPERFAMILY SSF160113 1 55 2.88E-8 T 14-10-2018 IPR036913 YegP-like superfamily MB46_06795 6ec5ba8ea729a013d6826e703def179a 101 Gene3D G3DSA:2.30.29.80 1 67 9.3E-6 T 14-10-2018 MB46_13235 c9be7a7bb4c61e57b4758d9fb813c3e6 633 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 633 1.2E-232 T 14-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 MB46_13235 c9be7a7bb4c61e57b4758d9fb813c3e6 633 Gene3D G3DSA:3.40.50.10490 467 618 7.5E-142 T 14-10-2018 MB46_13235 c9be7a7bb4c61e57b4758d9fb813c3e6 633 Gene3D G3DSA:3.40.50.10490 267 632 7.5E-142 T 14-10-2018 MB46_13235 c9be7a7bb4c61e57b4758d9fb813c3e6 633 Pfam PF01380 SIS domain 484 612 5.2E-23 T 14-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 MB46_13235 c9be7a7bb4c61e57b4758d9fb813c3e6 633 Pfam PF01380 SIS domain 310 435 4.3E-32 T 14-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 MB46_13235 c9be7a7bb4c61e57b4758d9fb813c3e6 633 SUPERFAMILY SSF56235 2 247 8.49E-59 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MB46_13235 c9be7a7bb4c61e57b4758d9fb813c3e6 633 Gene3D G3DSA:3.60.20.10 2 249 1.6E-65 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MB46_13235 c9be7a7bb4c61e57b4758d9fb813c3e6 633 SUPERFAMILY SSF53697 265 633 3.53E-109 T 14-10-2018 MB46_13235 c9be7a7bb4c61e57b4758d9fb813c3e6 633 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 633 39.311 T 14-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 MB46_13235 c9be7a7bb4c61e57b4758d9fb813c3e6 633 Pfam PF13522 Glutamine amidotransferase domain 77 204 3.6E-18 T 14-10-2018 MB46_15710 4d9127a7fa24e83da784ea9aa7e1ce58 228 Gene3D G3DSA:1.10.357.10 15 226 1.1E-61 T 14-10-2018 MB46_15710 4d9127a7fa24e83da784ea9aa7e1ce58 228 Pfam PF00440 Bacterial regulatory proteins, tetR family 30 74 9.7E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MB46_15710 4d9127a7fa24e83da784ea9aa7e1ce58 228 SUPERFAMILY SSF46689 28 83 9.98E-12 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MB46_15710 4d9127a7fa24e83da784ea9aa7e1ce58 228 PRINTS PR00400 Tetracycline repressor protein signature 42 65 1.7E-10 T 14-10-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 MB46_15710 4d9127a7fa24e83da784ea9aa7e1ce58 228 PRINTS PR00400 Tetracycline repressor protein signature 94 113 1.7E-10 T 14-10-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 MB46_15710 4d9127a7fa24e83da784ea9aa7e1ce58 228 PRINTS PR00400 Tetracycline repressor protein signature 151 170 1.7E-10 T 14-10-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 MB46_15710 4d9127a7fa24e83da784ea9aa7e1ce58 228 PRINTS PR00400 Tetracycline repressor protein signature 206 220 1.7E-10 T 14-10-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 MB46_15710 4d9127a7fa24e83da784ea9aa7e1ce58 228 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 43 1.3E-5 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MB46_15710 4d9127a7fa24e83da784ea9aa7e1ce58 228 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 51 74 1.3E-5 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MB46_15710 4d9127a7fa24e83da784ea9aa7e1ce58 228 SUPERFAMILY SSF48498 92 226 4.11E-25 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily MB46_15710 4d9127a7fa24e83da784ea9aa7e1ce58 228 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 93 223 4.7E-13 T 14-10-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 MB46_08400 e7c205a86a07c925a8732409d841ca56 166 Pfam PF00582 Universal stress protein family 22 155 3.4E-15 T 14-10-2018 IPR006016 UspA MB46_08400 e7c205a86a07c925a8732409d841ca56 166 Gene3D G3DSA:3.40.50.620 12 156 2.4E-17 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MB46_08400 e7c205a86a07c925a8732409d841ca56 166 SUPERFAMILY SSF52402 24 155 4.33E-17 T 14-10-2018 MB46_16120 3e8646e4c5b585508aa4e7e9b5cb0782 176 Pfam PF05258 Protein of unknown function (DUF721) 65 149 1.4E-24 T 14-10-2018 IPR007922 Protein of unknown function DUF721/UPF0232 MB46_13655 4645e7da91d4af1c120f5b58bfb214eb 321 Pfam PF00293 NUDIX domain 21 127 8.2E-16 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MB46_13655 4645e7da91d4af1c120f5b58bfb214eb 321 ProSitePatterns PS00893 Nudix box signature. 52 73 - T 14-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 MB46_13655 4645e7da91d4af1c120f5b58bfb214eb 321 SUPERFAMILY SSF55811 20 145 1.27E-27 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 MB46_13655 4645e7da91d4af1c120f5b58bfb214eb 321 Gene3D G3DSA:3.40.50.1240 155 321 1.2E-36 T 14-10-2018 IPR029033 Histidine phosphatase superfamily MB46_13655 4645e7da91d4af1c120f5b58bfb214eb 321 PRINTS PR00502 NUDIX hydrolase family signature 47 61 3.7E-5 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 MB46_13655 4645e7da91d4af1c120f5b58bfb214eb 321 PRINTS PR00502 NUDIX hydrolase family signature 61 76 3.7E-5 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 MB46_13655 4645e7da91d4af1c120f5b58bfb214eb 321 Gene3D G3DSA:3.90.79.10 17 152 2.3E-35 T 14-10-2018 MB46_13655 4645e7da91d4af1c120f5b58bfb214eb 321 SMART SM00855 155 269 9.5E-4 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MB46_13655 4645e7da91d4af1c120f5b58bfb214eb 321 SUPERFAMILY SSF53254 155 283 8.78E-15 T 14-10-2018 IPR029033 Histidine phosphatase superfamily MB46_13655 4645e7da91d4af1c120f5b58bfb214eb 321 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 156 236 1.5E-7 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MB46_00835 8ecf17e174d92b09ee43849c78712b57 416 Gene3D G3DSA:3.30.1540.10 235 326 6.1E-120 T 14-10-2018 MB46_00835 8ecf17e174d92b09ee43849c78712b57 416 Pfam PF02515 CoA-transferase family III 9 375 2.7E-122 T 14-10-2018 IPR003673 CoA-transferase family III GO:0003824 MB46_00835 8ecf17e174d92b09ee43849c78712b57 416 Gene3D G3DSA:3.40.50.10540 8 392 6.1E-120 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily MB46_00835 8ecf17e174d92b09ee43849c78712b57 416 SUPERFAMILY SSF89796 7 398 1.57E-121 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily MB46_16360 685970aabaa01153c97e8fff1a9a2718 254 SUPERFAMILY SSF53697 26 213 5.87E-16 T 14-10-2018 MB46_16360 685970aabaa01153c97e8fff1a9a2718 254 Pfam PF13580 SIS domain 11 150 3.0E-36 T 14-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 MB46_16360 685970aabaa01153c97e8fff1a9a2718 254 Gene3D G3DSA:3.40.50.10490 2 247 1.9E-70 T 14-10-2018 MB46_04505 3c30ce341b2ad58ab2a332e24c0d7c87 226 Gene3D G3DSA:3.40.50.1000 18 209 2.8E-46 T 14-10-2018 IPR023214 HAD superfamily MB46_04505 3c30ce341b2ad58ab2a332e24c0d7c87 226 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 19 186 9.9E-15 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MB46_04505 3c30ce341b2ad58ab2a332e24c0d7c87 226 Pfam PF13419 Haloacid dehalogenase-like hydrolase 20 188 2.7E-16 T 14-10-2018 MB46_04505 3c30ce341b2ad58ab2a332e24c0d7c87 226 Gene3D G3DSA:1.10.150.240 32 89 2.8E-46 T 14-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 MB46_04505 3c30ce341b2ad58ab2a332e24c0d7c87 226 SUPERFAMILY SSF56784 18 211 2.98E-37 T 14-10-2018 IPR036412 HAD-like superfamily MB46_01950 d49cde337286d3928312dd71d5fb30cb 521 SUPERFAMILY SSF52540 255 480 7.52E-39 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_01950 d49cde337286d3928312dd71d5fb30cb 521 Gene3D G3DSA:3.40.50.300 2 236 5.3E-56 T 14-10-2018 MB46_01950 d49cde337286d3928312dd71d5fb30cb 521 Gene3D G3DSA:3.40.50.300 254 508 5.8E-37 T 14-10-2018 MB46_01950 d49cde337286d3928312dd71d5fb30cb 521 SUPERFAMILY SSF52540 3 225 2.72E-58 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_01950 d49cde337286d3928312dd71d5fb30cb 521 Pfam PF00005 ABC transporter 271 427 2.5E-18 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_01950 d49cde337286d3928312dd71d5fb30cb 521 Pfam PF00005 ABC transporter 20 168 3.4E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_01950 d49cde337286d3928312dd71d5fb30cb 521 SMART SM00382 27 216 1.4E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_01950 d49cde337286d3928312dd71d5fb30cb 521 SMART SM00382 280 484 12.0 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_01950 d49cde337286d3928312dd71d5fb30cb 521 ProSitePatterns PS00211 ABC transporters family signature. 400 414 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_08360 ff26ab3d91f2d829c6d935324cf1407a 957 Gene3D G3DSA:3.40.640.10 97 358 8.1E-103 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MB46_08360 ff26ab3d91f2d829c6d935324cf1407a 957 Gene3D G3DSA:3.40.640.10 523 747 2.7E-56 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MB46_08360 ff26ab3d91f2d829c6d935324cf1407a 957 Gene3D G3DSA:3.90.1150.10 764 900 5.4E-37 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MB46_08360 ff26ab3d91f2d829c6d935324cf1407a 957 SUPERFAMILY SSF53383 483 949 7.82E-96 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MB46_08360 ff26ab3d91f2d829c6d935324cf1407a 957 SUPERFAMILY SSF53383 25 446 2.63E-95 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MB46_08360 ff26ab3d91f2d829c6d935324cf1407a 957 Pfam PF02347 Glycine cleavage system P-protein 17 447 7.4E-172 T 14-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 MB46_08360 ff26ab3d91f2d829c6d935324cf1407a 957 Pfam PF02347 Glycine cleavage system P-protein 478 737 1.3E-10 T 14-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 MB46_08360 ff26ab3d91f2d829c6d935324cf1407a 957 TIGRFAM TIGR00461 gcvP: glycine dehydrogenase 18 948 0.0 T 14-10-2018 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 MB46_08360 ff26ab3d91f2d829c6d935324cf1407a 957 Hamap MF_00711 Glycine dehydrogenase (decarboxylating) [gcvP]. 9 954 24.029 T 14-10-2018 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 MB46_17225 41a37cb660c43df0423f4f80a14f0e7f 871 SUPERFAMILY SSF52540 157 548 2.57E-93 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_17225 41a37cb660c43df0423f4f80a14f0e7f 871 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 634 652 - T 14-10-2018 IPR028299 ClpA/B, conserved site 2 MB46_17225 41a37cb660c43df0423f4f80a14f0e7f 871 Gene3D G3DSA:3.40.50.300 343 547 5.7E-67 T 14-10-2018 MB46_17225 41a37cb660c43df0423f4f80a14f0e7f 871 Pfam PF07724 AAA domain (Cdc48 subfamily) 599 761 9.6E-54 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MB46_17225 41a37cb660c43df0423f4f80a14f0e7f 871 SUPERFAMILY SSF52540 549 848 2.52E-77 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_17225 41a37cb660c43df0423f4f80a14f0e7f 871 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 294 306 - T 14-10-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 MB46_17225 41a37cb660c43df0423f4f80a14f0e7f 871 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 203 337 8.5E-14 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MB46_17225 41a37cb660c43df0423f4f80a14f0e7f 871 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 711 725 3.4E-41 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 MB46_17225 41a37cb660c43df0423f4f80a14f0e7f 871 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 678 696 3.4E-41 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 MB46_17225 41a37cb660c43df0423f4f80a14f0e7f 871 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 604 622 3.4E-41 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 MB46_17225 41a37cb660c43df0423f4f80a14f0e7f 871 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 649 667 3.4E-41 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 MB46_17225 41a37cb660c43df0423f4f80a14f0e7f 871 Gene3D G3DSA:1.10.8.60 767 865 3.3E-29 T 14-10-2018 MB46_17225 41a37cb660c43df0423f4f80a14f0e7f 871 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 767 847 6.9E-26 T 14-10-2018 IPR019489 Clp ATPase, C-terminal MB46_17225 41a37cb660c43df0423f4f80a14f0e7f 871 SUPERFAMILY SSF81923 4 156 2.75E-34 T 14-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 MB46_17225 41a37cb660c43df0423f4f80a14f0e7f 871 SMART SM00382 600 768 1.2E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_17225 41a37cb660c43df0423f4f80a14f0e7f 871 SMART SM00382 198 343 1.9E-8 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_17225 41a37cb660c43df0423f4f80a14f0e7f 871 Gene3D G3DSA:1.10.1780.10 3 148 1.2E-29 T 14-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 MB46_17225 41a37cb660c43df0423f4f80a14f0e7f 871 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 5 851 0.0 T 14-10-2018 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0042026 MB46_17225 41a37cb660c43df0423f4f80a14f0e7f 871 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 94 145 1.4E-13 T 14-10-2018 IPR004176 Clp, N-terminal MB46_17225 41a37cb660c43df0423f4f80a14f0e7f 871 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 20 59 2.5E-9 T 14-10-2018 IPR004176 Clp, N-terminal MB46_17225 41a37cb660c43df0423f4f80a14f0e7f 871 SMART SM01086 767 858 1.8E-33 T 14-10-2018 IPR019489 Clp ATPase, C-terminal MB46_17225 41a37cb660c43df0423f4f80a14f0e7f 871 Gene3D G3DSA:3.40.50.300 149 342 2.4E-73 T 14-10-2018 MB46_17225 41a37cb660c43df0423f4f80a14f0e7f 871 Gene3D G3DSA:3.40.50.300 553 766 1.6E-85 T 14-10-2018 MB46_13530 debdd8ff4cadccf2d4e8fdf166498de9 96 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 36 87 7.7E-19 T 14-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 MB46_13530 debdd8ff4cadccf2d4e8fdf166498de9 96 Gene3D G3DSA:1.20.5.1030 29 87 1.3E-16 T 14-10-2018 IPR038379 SecE superfamily MB46_13530 debdd8ff4cadccf2d4e8fdf166498de9 96 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 34 89 4.1E-18 T 14-10-2018 IPR005807 SecE subunit of protein translocation complex, bacterial-like GO:0009306|GO:0015450|GO:0016021 MB46_13530 debdd8ff4cadccf2d4e8fdf166498de9 96 Hamap MF_00422 Protein translocase subunit SecE [secE]. 31 86 12.71 T 14-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 MB46_18045 ce6da562f009104f2fdb1485384740be 217 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 117 152 8.9E-8 T 14-10-2018 IPR001451 Hexapeptide repeat MB46_18045 ce6da562f009104f2fdb1485384740be 217 Gene3D G3DSA:2.160.10.10 2 216 7.0E-63 T 14-10-2018 MB46_18045 ce6da562f009104f2fdb1485384740be 217 SUPERFAMILY SSF51161 55 200 1.52E-41 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily MB46_02045 b5536baa8e95343ba8cecda4c17e233a 395 Pfam PF03741 Integral membrane protein TerC family 69 272 1.3E-49 T 14-10-2018 IPR005496 Integral membrane protein TerC GO:0016021 MB46_02045 b5536baa8e95343ba8cecda4c17e233a 395 TIGRFAM TIGR03718 R_switched_Alx: integral membrane protein, TerC family 5 317 7.0E-110 T 14-10-2018 IPR022369 Integral membrane protein TerC, riboswitch-linked GO:0016021 MB46_03375 27c3ce9fdfdb83e901c117bf72f31f3f 401 Gene3D G3DSA:3.40.50.2000 209 378 4.5E-42 T 14-10-2018 MB46_03375 27c3ce9fdfdb83e901c117bf72f31f3f 401 Pfam PF13439 Glycosyltransferase Family 4 26 200 3.1E-22 T 14-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 MB46_03375 27c3ce9fdfdb83e901c117bf72f31f3f 401 SUPERFAMILY SSF53756 15 392 7.14E-76 T 14-10-2018 MB46_03375 27c3ce9fdfdb83e901c117bf72f31f3f 401 Gene3D G3DSA:3.40.50.2000 11 208 1.3E-29 T 14-10-2018 MB46_03375 27c3ce9fdfdb83e901c117bf72f31f3f 401 Pfam PF00534 Glycosyl transferases group 1 214 370 2.7E-37 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 MB46_11140 ada3fa4c3a9ecbabeee7af93e5dc324a 485 Pfam PF02614 Glucuronate isomerase 39 475 7.5E-74 T 14-10-2018 IPR003766 Uronate isomerase GO:0006064|GO:0008880 KEGG: 00040+5.3.1.12|MetaCyc: PWY-7247|MetaCyc: PWY-7248 MB46_11140 ada3fa4c3a9ecbabeee7af93e5dc324a 485 Gene3D G3DSA:1.10.2020.10 69 165 1.9E-127 T 14-10-2018 MB46_11140 ada3fa4c3a9ecbabeee7af93e5dc324a 485 Gene3D G3DSA:3.20.20.140 38 471 1.9E-127 T 14-10-2018 MB46_11140 ada3fa4c3a9ecbabeee7af93e5dc324a 485 SUPERFAMILY SSF51556 24 484 5.44E-140 T 14-10-2018 IPR032466 Metal-dependent hydrolase MB46_17805 61bc2771b28c2d58bba26594e479ada0 163 SUPERFAMILY SSF82784 7 160 6.28E-39 T 14-10-2018 IPR036102 OsmC/Ohr superfamily MB46_17805 61bc2771b28c2d58bba26594e479ada0 163 Gene3D G3DSA:3.30.300.20 3 149 1.4E-41 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta MB46_17805 61bc2771b28c2d58bba26594e479ada0 163 Pfam PF02566 OsmC-like protein 54 158 1.3E-19 T 14-10-2018 IPR003718 OsmC/Ohr family MB46_10990 cb51d150f735e1a73250ffb3c636d4e9 163 SUPERFAMILY SSF55729 12 156 2.7E-24 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase MB46_10990 cb51d150f735e1a73250ffb3c636d4e9 163 Pfam PF00583 Acetyltransferase (GNAT) family 40 151 2.8E-13 T 14-10-2018 IPR000182 GNAT domain MB46_10990 cb51d150f735e1a73250ffb3c636d4e9 163 Gene3D G3DSA:3.40.630.30 9 162 7.9E-31 T 14-10-2018 MB46_00860 693e3bbae97e8547588f278775dad9f6 266 SUPERFAMILY SSF55781 102 258 1.5E-27 T 14-10-2018 MB46_00860 693e3bbae97e8547588f278775dad9f6 266 SMART SM00346 26 115 2.6E-8 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 MB46_00860 693e3bbae97e8547588f278775dad9f6 266 SUPERFAMILY SSF46785 29 98 7.02E-10 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_00860 693e3bbae97e8547588f278775dad9f6 266 Gene3D G3DSA:1.10.10.10 28 96 1.5E-12 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_00860 693e3bbae97e8547588f278775dad9f6 266 Gene3D G3DSA:3.30.450.40 97 257 3.6E-38 T 14-10-2018 IPR029016 GAF-like domain superfamily MB46_00860 693e3bbae97e8547588f278775dad9f6 266 Pfam PF09339 IclR helix-turn-helix domain 29 75 1.5E-8 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 MB46_00860 693e3bbae97e8547588f278775dad9f6 266 Pfam PF01614 Bacterial transcriptional regulator 144 255 6.0E-11 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal MB46_02215 348071f11c0bcf5559a3d2d9a9b2fe1f 200 Pfam PF04480 Protein of unknown function (DUF559) 104 173 8.9E-5 T 14-10-2018 IPR007569 Protein of unknown function DUF559 MB46_02215 348071f11c0bcf5559a3d2d9a9b2fe1f 200 Gene3D G3DSA:3.40.960.10 72 175 7.9E-11 T 14-10-2018 MB46_06110 4589a97798b219ab021ee90b777eb96a 472 Gene3D G3DSA:3.90.1300.10 1 466 4.3E-102 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 MB46_06110 4589a97798b219ab021ee90b777eb96a 472 SUPERFAMILY SSF75304 6 451 1.23E-100 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 MB46_06110 4589a97798b219ab021ee90b777eb96a 472 Pfam PF01425 Amidase 25 442 9.4E-71 T 14-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 MB46_17385 f5a5a2aa375afdc93c03db9bd8f83172 228 Pfam PF00293 NUDIX domain 67 168 2.8E-11 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MB46_17385 f5a5a2aa375afdc93c03db9bd8f83172 228 SUPERFAMILY SSF55811 67 205 7.45E-28 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 MB46_17385 f5a5a2aa375afdc93c03db9bd8f83172 228 Gene3D G3DSA:3.90.79.10 30 211 4.5E-41 T 14-10-2018 MB46_16710 d5ace1758f08433d81b61a4d0d203bd9 337 PIRSF PIRSF015753 5 317 1.8E-110 T 14-10-2018 IPR016639 Glutathione S-transferase Omega/GSH GO:0004364 MB46_16710 d5ace1758f08433d81b61a4d0d203bd9 337 Pfam PF13409 Glutathione S-transferase, N-terminal domain 56 138 4.7E-9 T 14-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 MB46_16710 d5ace1758f08433d81b61a4d0d203bd9 337 SUPERFAMILY SSF47616 179 328 1.39E-32 T 14-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily MB46_16710 d5ace1758f08433d81b61a4d0d203bd9 337 Pfam PF13410 Glutathione S-transferase, C-terminal domain 197 266 1.0E-12 T 14-10-2018 MB46_16710 d5ace1758f08433d81b61a4d0d203bd9 337 Gene3D G3DSA:1.20.1050.10 174 337 3.8E-72 T 14-10-2018 MB46_16710 d5ace1758f08433d81b61a4d0d203bd9 337 Gene3D G3DSA:3.40.30.130 3 171 2.2E-56 T 14-10-2018 MB46_05960 2066e07272d5cf6fcec89e905ea927a1 656 Gene3D G3DSA:3.40.50.12780 51 520 1.4E-100 T 14-10-2018 MB46_05960 2066e07272d5cf6fcec89e905ea927a1 656 TIGRFAM TIGR02188 Ac_CoA_lig_AcsA: acetate--CoA ligase 27 643 4.7E-233 T 14-10-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 MB46_05960 2066e07272d5cf6fcec89e905ea927a1 656 ProSitePatterns PS00455 Putative AMP-binding domain signature. 258 269 - T 14-10-2018 IPR020845 AMP-binding, conserved site MB46_05960 2066e07272d5cf6fcec89e905ea927a1 656 Gene3D G3DSA:3.30.300.30 523 651 1.7E-26 T 14-10-2018 MB46_05960 2066e07272d5cf6fcec89e905ea927a1 656 SUPERFAMILY SSF56801 29 625 1.57E-155 T 14-10-2018 MB46_05960 2066e07272d5cf6fcec89e905ea927a1 656 Pfam PF13193 AMP-binding enzyme C-terminal domain 536 613 2.7E-22 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain MB46_05960 2066e07272d5cf6fcec89e905ea927a1 656 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 28 80 7.5E-11 T 14-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 MB46_05960 2066e07272d5cf6fcec89e905ea927a1 656 Pfam PF00501 AMP-binding enzyme 87 527 6.9E-90 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 MB46_07065 bca17483725d2fcdb552eaa4f64f3747 490 Gene3D G3DSA:3.90.850.10 1 206 4.0E-56 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 MB46_07065 bca17483725d2fcdb552eaa4f64f3747 490 Pfam PF03737 Aldolase/RraA 267 429 9.6E-31 T 14-10-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein MB46_07065 bca17483725d2fcdb552eaa4f64f3747 490 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 24 216 7.4E-49 T 14-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 MB46_07065 bca17483725d2fcdb552eaa4f64f3747 490 Gene3D G3DSA:3.50.30.100 244 451 2.2E-50 T 14-10-2018 MB46_07065 bca17483725d2fcdb552eaa4f64f3747 490 SUPERFAMILY SSF89562 263 438 2.49E-37 T 14-10-2018 IPR036704 Ribonuclease E inhibitor RraA/RraA-like superfamily MB46_07065 bca17483725d2fcdb552eaa4f64f3747 490 SUPERFAMILY SSF56529 12 219 2.75E-52 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 MB46_09210 e17d42c1599687a247e71875100ee25b 528 Pfam PF16655 PhoD-like phosphatase, N-terminal domain 44 142 3.6E-29 T 14-10-2018 IPR032093 Phospholipase D, N-terminal MB46_09210 e17d42c1599687a247e71875100ee25b 528 SUPERFAMILY SSF56300 154 500 7.27E-31 T 14-10-2018 MB46_09210 e17d42c1599687a247e71875100ee25b 528 Gene3D G3DSA:2.60.40.380 35 145 8.5E-35 T 14-10-2018 IPR008963 Purple acid phosphatase-like, N-terminal GO:0003993|GO:0046872 MB46_09210 e17d42c1599687a247e71875100ee25b 528 Gene3D G3DSA:3.60.21.70 147 528 6.5E-139 T 14-10-2018 IPR038607 PhoD-like superfamily MB46_09210 e17d42c1599687a247e71875100ee25b 528 Pfam PF09423 PhoD-like phosphatase 155 497 8.5E-112 T 14-10-2018 IPR018946 Alkaline phosphatase D-related MB46_03800 981de9c305a53dbb97708c6a8c077e91 307 SUPERFAMILY SSF52374 10 169 1.04E-27 T 14-10-2018 MB46_03800 981de9c305a53dbb97708c6a8c077e91 307 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 13 306 7.2E-62 T 14-10-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 MB46_03800 981de9c305a53dbb97708c6a8c077e91 307 SUPERFAMILY SSF82114 166 307 7.41E-38 T 14-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 MB46_03800 981de9c305a53dbb97708c6a8c077e91 307 PIRSF PIRSF004491 1 307 1.3E-87 T 14-10-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 MB46_03800 981de9c305a53dbb97708c6a8c077e91 307 Pfam PF01687 Riboflavin kinase 177 306 1.2E-30 T 14-10-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26|MetaCyc: PWY-5523|MetaCyc: PWY-6168|MetaCyc: PWY-7863|Reactome: R-HSA-196843 MB46_03800 981de9c305a53dbb97708c6a8c077e91 307 Gene3D G3DSA:2.40.30.30 179 307 6.9E-38 T 14-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 MB46_03800 981de9c305a53dbb97708c6a8c077e91 307 Pfam PF06574 FAD synthetase 7 152 2.8E-47 T 14-10-2018 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 MB46_03800 981de9c305a53dbb97708c6a8c077e91 307 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 12 64 1.3E-7 T 14-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 MB46_03800 981de9c305a53dbb97708c6a8c077e91 307 Gene3D G3DSA:3.40.50.620 1 178 5.4E-60 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MB46_03800 981de9c305a53dbb97708c6a8c077e91 307 SMART SM00904 176 307 2.0E-50 T 14-10-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26|MetaCyc: PWY-5523|MetaCyc: PWY-6168|MetaCyc: PWY-7863|Reactome: R-HSA-196843 MB46_00940 9b381d3e62743923b5662bb57f0a18a2 236 Pfam PF00486 Transcriptional regulatory protein, C terminal 154 230 3.9E-26 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MB46_00940 9b381d3e62743923b5662bb57f0a18a2 236 Gene3D G3DSA:3.40.50.2300 5 134 7.5E-40 T 14-10-2018 MB46_00940 9b381d3e62743923b5662bb57f0a18a2 236 SUPERFAMILY SSF46894 130 231 1.02E-29 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MB46_00940 9b381d3e62743923b5662bb57f0a18a2 236 SUPERFAMILY SSF52172 7 132 2.28E-44 T 14-10-2018 IPR011006 CheY-like superfamily MB46_00940 9b381d3e62743923b5662bb57f0a18a2 236 SMART SM00862 154 230 4.6E-27 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MB46_00940 9b381d3e62743923b5662bb57f0a18a2 236 SMART SM00448 8 119 2.0E-46 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MB46_00940 9b381d3e62743923b5662bb57f0a18a2 236 Gene3D G3DSA:1.10.10.10 135 236 1.1E-34 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_00940 9b381d3e62743923b5662bb57f0a18a2 236 Pfam PF00072 Response regulator receiver domain 11 120 3.8E-30 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MB46_04200 880d40ca846fd60c422f92e95f9a271f 183 Hamap MF_00004 Adenine phosphoribosyltransferase [apt]. 17 183 32.526 T 14-10-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 MB46_04200 880d40ca846fd60c422f92e95f9a271f 183 Gene3D G3DSA:3.40.50.2020 10 182 2.9E-52 T 14-10-2018 MB46_04200 880d40ca846fd60c422f92e95f9a271f 183 SUPERFAMILY SSF53271 23 174 2.35E-40 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like MB46_04200 880d40ca846fd60c422f92e95f9a271f 183 Pfam PF00156 Phosphoribosyl transferase domain 53 160 7.7E-14 T 14-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 MB46_17350 ee3ae093888bdc98ebdaab4b539893b0 298 SUPERFAMILY SSF161098 19 298 6.82E-62 T 14-10-2018 IPR035906 MetI-like superfamily MB46_17350 ee3ae093888bdc98ebdaab4b539893b0 298 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 100 291 9.0E-18 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_17350 ee3ae093888bdc98ebdaab4b539893b0 298 Gene3D G3DSA:1.10.3720.10 17 285 1.1E-51 T 14-10-2018 IPR035906 MetI-like superfamily MB46_17005 4063d916918fc1ec8f41f419a02d371d 350 Gene3D G3DSA:1.10.260.40 1 60 6.8E-20 T 14-10-2018 MB46_17005 4063d916918fc1ec8f41f419a02d371d 350 Gene3D G3DSA:3.40.50.2300 61 317 5.6E-66 T 14-10-2018 MB46_17005 4063d916918fc1ec8f41f419a02d371d 350 SUPERFAMILY SSF47413 4 64 1.05E-13 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MB46_17005 4063d916918fc1ec8f41f419a02d371d 350 Gene3D G3DSA:3.40.50.2300 165 300 5.6E-66 T 14-10-2018 MB46_17005 4063d916918fc1ec8f41f419a02d371d 350 SUPERFAMILY SSF53822 66 345 5.44E-56 T 14-10-2018 IPR028082 Periplasmic binding protein-like I MB46_17005 4063d916918fc1ec8f41f419a02d371d 350 SMART SM00354 4 76 3.5E-23 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MB46_17005 4063d916918fc1ec8f41f419a02d371d 350 Pfam PF00356 Bacterial regulatory proteins, lacI family 8 53 4.6E-13 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MB46_17005 4063d916918fc1ec8f41f419a02d371d 350 Pfam PF13377 Periplasmic binding protein-like domain 174 342 3.2E-35 T 14-10-2018 MB46_18650 52f76f7bbfcf62ae0e8ea6344bb4a0db 127 ProDom PD030784 PRECURSOR SIGNAL TRANSCRIPTIONAL PROBABLE RV1990C/MT2044 REGULATORY MB3210 MB2012C 38 121 6.0E-10 T 14-10-2018 MB46_08945 37fad80a9a561a6247a316c451fb5dba 426 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 13 425 40.286 T 14-10-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 MB46_08945 37fad80a9a561a6247a316c451fb5dba 426 Gene3D G3DSA:3.40.309.10 234 383 6.3E-156 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 MB46_08945 37fad80a9a561a6247a316c451fb5dba 426 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 21 415 4.2E-145 T 14-10-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 MB46_08945 37fad80a9a561a6247a316c451fb5dba 426 Pfam PF00171 Aldehyde dehydrogenase family 9 298 3.2E-10 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 MB46_08945 37fad80a9a561a6247a316c451fb5dba 426 ProSitePatterns PS01223 Gamma-glutamyl phosphate reductase signature. 332 353 - T 14-10-2018 IPR020593 Gamma-glutamyl phosphate reductase GPR, conserved site GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 MB46_08945 37fad80a9a561a6247a316c451fb5dba 426 PIRSF PIRSF000151 6 426 1.6E-166 T 14-10-2018 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922 MB46_08945 37fad80a9a561a6247a316c451fb5dba 426 Gene3D G3DSA:3.40.605.10 26 420 6.3E-156 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 MB46_08945 37fad80a9a561a6247a316c451fb5dba 426 SUPERFAMILY SSF53720 12 425 1.44E-109 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 MB46_15295 c1441b4e7ada4f36c4fb083b4b9a07d2 277 SUPERFAMILY SSF53613 8 265 7.17E-54 T 14-10-2018 IPR029056 Ribokinase-like MB46_15295 c1441b4e7ada4f36c4fb083b4b9a07d2 277 Pfam PF08543 Phosphomethylpyrimidine kinase 18 264 2.0E-59 T 14-10-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 MB46_15295 c1441b4e7ada4f36c4fb083b4b9a07d2 277 Gene3D G3DSA:3.40.1190.20 7 270 8.6E-65 T 14-10-2018 IPR029056 Ribokinase-like MB46_11670 7775937d1c9981a73d2ee774651aa3c4 430 Pfam PF01882 Protein of unknown function DUF58 186 271 1.2E-21 T 14-10-2018 IPR002881 Domain of unknown function DUF58 MB46_19090 882251578f89248304f6f922755b2f8e 739 TIGRFAM TIGR02100 glgX_debranch: glycogen debranching enzyme GlgX 34 653 4.0E-206 T 14-10-2018 IPR011837 Glycogen debranching enzyme, GlgX type GO:0004133|GO:0004553|GO:0005980 MB46_19090 882251578f89248304f6f922755b2f8e 739 Gene3D G3DSA:3.20.20.80 139 590 1.5E-161 T 14-10-2018 MB46_19090 882251578f89248304f6f922755b2f8e 739 SMART SM00642 163 578 2.1E-6 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MB46_19090 882251578f89248304f6f922755b2f8e 739 Gene3D G3DSA:2.60.40.1180 595 655 4.2E-6 T 14-10-2018 IPR013780 Glycosyl hydrolase, all-beta MB46_19090 882251578f89248304f6f922755b2f8e 739 SUPERFAMILY SSF51011 598 653 3.02E-7 T 14-10-2018 MB46_19090 882251578f89248304f6f922755b2f8e 739 SUPERFAMILY SSF81296 19 145 1.62E-10 T 14-10-2018 IPR014756 Immunoglobulin E-set MB46_19090 882251578f89248304f6f922755b2f8e 739 Pfam PF00128 Alpha amylase, catalytic domain 190 301 1.8E-4 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MB46_19090 882251578f89248304f6f922755b2f8e 739 Pfam PF00128 Alpha amylase, catalytic domain 311 541 5.2E-5 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MB46_19090 882251578f89248304f6f922755b2f8e 739 Gene3D G3DSA:2.60.40.10 4 138 3.6E-12 T 14-10-2018 IPR013783 Immunoglobulin-like fold MB46_19090 882251578f89248304f6f922755b2f8e 739 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 34 103 3.6E-5 T 14-10-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 MB46_19090 882251578f89248304f6f922755b2f8e 739 SUPERFAMILY SSF51445 134 580 1.2E-116 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily MB46_02070 12bedbdc71c1e9ff6ab54e029b5e47be 385 Pfam PF01594 AI-2E family transporter 14 333 8.4E-60 T 14-10-2018 IPR002549 Transmembrane protein TqsA-like MB46_06435 06419dafba6de0afcd3e3eae247784c3 503 Pfam PF02838 Glycosyl hydrolase family 20, domain 2 7 142 8.1E-10 T 14-10-2018 IPR015882 Beta-hexosaminidase, bacterial type, N-terminal MB46_06435 06419dafba6de0afcd3e3eae247784c3 503 Gene3D G3DSA:3.30.379.10 3 139 4.8E-16 T 14-10-2018 IPR029018 Beta-hexosaminidase-like, domain 2 MB46_06435 06419dafba6de0afcd3e3eae247784c3 503 SUPERFAMILY SSF51445 145 468 3.61E-67 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily MB46_06435 06419dafba6de0afcd3e3eae247784c3 503 Pfam PF00728 Glycosyl hydrolase family 20, catalytic domain 145 306 4.7E-25 T 14-10-2018 IPR015883 Glycoside hydrolase family 20, catalytic domain GO:0004553|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883 MB46_06435 06419dafba6de0afcd3e3eae247784c3 503 PRINTS PR00738 Glycosyl hydrolase family 20 signature 168 189 8.3E-17 T 14-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 MB46_06435 06419dafba6de0afcd3e3eae247784c3 503 PRINTS PR00738 Glycosyl hydrolase family 20 signature 104 124 8.3E-17 T 14-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 MB46_06435 06419dafba6de0afcd3e3eae247784c3 503 PRINTS PR00738 Glycosyl hydrolase family 20 signature 139 156 8.3E-17 T 14-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 MB46_06435 06419dafba6de0afcd3e3eae247784c3 503 PRINTS PR00738 Glycosyl hydrolase family 20 signature 233 250 8.3E-17 T 14-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 MB46_06435 06419dafba6de0afcd3e3eae247784c3 503 PRINTS PR00738 Glycosyl hydrolase family 20 signature 293 306 8.3E-17 T 14-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 MB46_06435 06419dafba6de0afcd3e3eae247784c3 503 SUPERFAMILY SSF55545 7 144 7.78E-11 T 14-10-2018 IPR029018 Beta-hexosaminidase-like, domain 2 MB46_06435 06419dafba6de0afcd3e3eae247784c3 503 Gene3D G3DSA:3.20.20.80 142 488 6.2E-68 T 14-10-2018 MB46_05990 71fa1f926fa270ab49c54397657428b3 312 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 107 309 1.5E-13 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_05990 71fa1f926fa270ab49c54397657428b3 312 SUPERFAMILY SSF161098 75 300 4.32E-59 T 14-10-2018 IPR035906 MetI-like superfamily MB46_05990 71fa1f926fa270ab49c54397657428b3 312 Gene3D G3DSA:1.10.3720.10 71 311 1.9E-67 T 14-10-2018 IPR035906 MetI-like superfamily MB46_17010 8ca6262f016c70561e6c3fd25e00eaee 510 Pfam PF01381 Helix-turn-helix 13 60 3.4E-10 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MB46_17010 8ca6262f016c70561e6c3fd25e00eaee 510 Gene3D G3DSA:1.10.260.40 4 64 4.6E-12 T 14-10-2018 MB46_17010 8ca6262f016c70561e6c3fd25e00eaee 510 SUPERFAMILY SSF55205 77 509 2.13E-91 T 14-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 MB46_17010 8ca6262f016c70561e6c3fd25e00eaee 510 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 81 498 6.6E-43 T 14-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 MB46_17010 8ca6262f016c70561e6c3fd25e00eaee 510 Gene3D G3DSA:3.65.10.10 95 308 2.7E-115 T 14-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 MB46_17010 8ca6262f016c70561e6c3fd25e00eaee 510 Gene3D G3DSA:3.65.10.10 80 505 2.7E-115 T 14-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 MB46_17010 8ca6262f016c70561e6c3fd25e00eaee 510 SMART SM00530 12 67 3.1E-9 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MB46_17010 8ca6262f016c70561e6c3fd25e00eaee 510 SUPERFAMILY SSF47413 7 64 3.49E-11 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MB46_19480 e1b8eb636762941785599dd34ee6f2a2 322 SUPERFAMILY SSF46785 246 315 3.15E-9 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_19480 e1b8eb636762941785599dd34ee6f2a2 322 SMART SM00418 245 320 0.0065 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MB46_19480 e1b8eb636762941785599dd34ee6f2a2 322 Gene3D G3DSA:1.10.10.10 244 317 4.8E-9 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_03305 ec759a93ee9ae743a904570124733416 657 Pfam PF08278 DNA primase DnaG DnaB-binding 513 637 4.5E-12 T 14-10-2018 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 MB46_03305 ec759a93ee9ae743a904570124733416 657 Pfam PF08275 DNA primase catalytic core, N-terminal domain 128 254 5.8E-38 T 14-10-2018 IPR013264 DNA primase, catalytic core, N-terminal MB46_03305 ec759a93ee9ae743a904570124733416 657 SUPERFAMILY SSF57783 5 101 1.7E-31 T 14-10-2018 MB46_03305 ec759a93ee9ae743a904570124733416 657 Pfam PF01807 CHC2 zinc finger 6 101 1.3E-33 T 14-10-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 MB46_03305 ec759a93ee9ae743a904570124733416 657 Pfam PF10410 DnaB-helicase binding domain of primase 375 427 1.2E-12 T 14-10-2018 IPR019475 DNA primase, DnaB-helicase binding domain GO:0016779 MB46_03305 ec759a93ee9ae743a904570124733416 657 TIGRFAM TIGR01391 dnaG: DNA primase 5 422 5.4E-115 T 14-10-2018 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 MB46_03305 ec759a93ee9ae743a904570124733416 657 SMART SM00493 262 339 6.2E-14 T 14-10-2018 IPR006171 TOPRIM domain MB46_03305 ec759a93ee9ae743a904570124733416 657 Gene3D G3DSA:3.90.580.10 5 102 3.7E-34 T 14-10-2018 IPR036977 DNA Primase, CHC2-type zinc finger GO:0003677|GO:0006260|GO:0008270 MB46_03305 ec759a93ee9ae743a904570124733416 657 Gene3D G3DSA:3.40.1360.10 244 373 6.6E-36 T 14-10-2018 MB46_03305 ec759a93ee9ae743a904570124733416 657 PIRSF PIRSF002811 2 654 1.4E-143 T 14-10-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 MB46_03305 ec759a93ee9ae743a904570124733416 657 SUPERFAMILY SSF56731 118 430 5.23E-93 T 14-10-2018 MB46_03305 ec759a93ee9ae743a904570124733416 657 SMART SM00400 37 91 1.2E-32 T 14-10-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 MB46_03305 ec759a93ee9ae743a904570124733416 657 Gene3D G3DSA:3.90.980.10 112 243 4.3E-37 T 14-10-2018 IPR037068 DNA primase, catalytic core, N-terminal domain superfamily MB46_03305 ec759a93ee9ae743a904570124733416 657 Hamap MF_00974 DNA primase [dnaG]. 4 645 26.023 T 14-10-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 MB46_03305 ec759a93ee9ae743a904570124733416 657 Pfam PF13662 Toprim domain 263 335 1.3E-16 T 14-10-2018 IPR006171 TOPRIM domain MB46_13940 c469212f70da6359cca31d0f7f3e8989 344 Gene3D G3DSA:3.40.190.10 47 293 6.6E-63 T 14-10-2018 MB46_13940 c469212f70da6359cca31d0f7f3e8989 344 TIGRFAM TIGR01728 SsuA_fam: ABC transporter, substrate-binding protein, aliphatic sulfonates family 51 327 2.2E-63 T 14-10-2018 IPR010067 Aliphatic sulfonates-binding protein GO:0016020|GO:0042626 MB46_13940 c469212f70da6359cca31d0f7f3e8989 344 Pfam PF09084 NMT1/THI5 like 59 260 4.6E-25 T 14-10-2018 IPR015168 SsuA/THI5-like MB46_13940 c469212f70da6359cca31d0f7f3e8989 344 Gene3D G3DSA:1.10.8.450 252 285 6.6E-63 T 14-10-2018 MB46_13940 c469212f70da6359cca31d0f7f3e8989 344 SMART SM00062 43 257 0.0029 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MB46_13940 c469212f70da6359cca31d0f7f3e8989 344 Gene3D G3DSA:3.40.190.10 123 221 6.6E-63 T 14-10-2018 MB46_13940 c469212f70da6359cca31d0f7f3e8989 344 SUPERFAMILY SSF53850 61 273 2.65E-45 T 14-10-2018 MB46_15175 a93449be037360c3cae864ab0d19da0e 103 Gene3D G3DSA:1.10.10.10 3 102 3.1E-15 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_15175 a93449be037360c3cae864ab0d19da0e 103 SUPERFAMILY SSF46785 5 97 1.36E-16 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_15175 a93449be037360c3cae864ab0d19da0e 103 SMART SM00418 19 97 3.5E-9 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MB46_15175 a93449be037360c3cae864ab0d19da0e 103 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 21 36 3.4E-6 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MB46_15175 a93449be037360c3cae864ab0d19da0e 103 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 53 68 3.4E-6 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MB46_15175 a93449be037360c3cae864ab0d19da0e 103 Pfam PF12840 Helix-turn-helix domain 18 72 1.7E-7 T 14-10-2018 MB46_12010 a7e97740e50b12d1f62c9502c5ab197b 236 SUPERFAMILY SSF161098 8 201 1.44E-38 T 14-10-2018 IPR035906 MetI-like superfamily MB46_12010 a7e97740e50b12d1f62c9502c5ab197b 236 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 27 216 7.1E-24 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_12010 a7e97740e50b12d1f62c9502c5ab197b 236 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 8 107 3.8E-18 T 14-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 MB46_12010 a7e97740e50b12d1f62c9502c5ab197b 236 Gene3D G3DSA:1.10.3720.10 4 220 2.4E-48 T 14-10-2018 IPR035906 MetI-like superfamily MB46_12750 4d9f41aed430df40c75e68460a03269b 235 SUPERFAMILY SSF55811 10 146 1.76E-18 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 MB46_12750 4d9f41aed430df40c75e68460a03269b 235 Gene3D G3DSA:3.90.79.10 3 84 1.0E-17 T 14-10-2018 MB46_12750 4d9f41aed430df40c75e68460a03269b 235 Gene3D G3DSA:3.90.79.10 85 180 1.3E-16 T 14-10-2018 MB46_12750 4d9f41aed430df40c75e68460a03269b 235 Pfam PF00293 NUDIX domain 11 138 5.2E-11 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MB46_16025 867a60c4baf363f26700eb355a7a1765 166 Gene3D G3DSA:3.90.79.10 18 165 1.9E-30 T 14-10-2018 MB46_16025 867a60c4baf363f26700eb355a7a1765 166 ProSitePatterns PS00893 Nudix box signature. 61 82 - T 14-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 MB46_16025 867a60c4baf363f26700eb355a7a1765 166 Pfam PF00293 NUDIX domain 28 152 7.4E-19 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MB46_16025 867a60c4baf363f26700eb355a7a1765 166 SUPERFAMILY SSF55811 26 162 2.98E-29 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 MB46_09215 e4d264cc837ac557439fb7dca29af309 333 SUPERFAMILY SSF54637 166 306 2.99E-37 T 14-10-2018 IPR029069 HotDog domain superfamily MB46_09215 e4d264cc837ac557439fb7dca29af309 333 Pfam PF03061 Thioesterase superfamily 182 256 6.3E-16 T 14-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 MB46_09215 e4d264cc837ac557439fb7dca29af309 333 Pfam PF03061 Thioesterase superfamily 28 97 3.5E-12 T 14-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 MB46_09215 e4d264cc837ac557439fb7dca29af309 333 Gene3D G3DSA:3.10.129.10 2 156 1.3E-35 T 14-10-2018 MB46_09215 e4d264cc837ac557439fb7dca29af309 333 Gene3D G3DSA:3.10.129.10 157 313 2.2E-38 T 14-10-2018 MB46_09215 e4d264cc837ac557439fb7dca29af309 333 SUPERFAMILY SSF54637 6 149 1.77E-32 T 14-10-2018 IPR029069 HotDog domain superfamily MB46_11240 3f3c176f12aed829d9ea724fa133df08 444 SUPERFAMILY SSF55205 12 428 4.3E-94 T 14-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 MB46_11240 3f3c176f12aed829d9ea724fa133df08 444 ProSitePatterns PS00885 EPSP synthase signature 2. 344 362 - T 14-10-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 MB46_11240 3f3c176f12aed829d9ea724fa133df08 444 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 18 430 1.4E-105 T 14-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 MB46_11240 3f3c176f12aed829d9ea724fa133df08 444 Gene3D G3DSA:3.65.10.10 17 421 9.4E-129 T 14-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 MB46_11240 3f3c176f12aed829d9ea724fa133df08 444 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 13 423 5.9E-103 T 14-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 MB46_11240 3f3c176f12aed829d9ea724fa133df08 444 Gene3D G3DSA:3.65.10.10 25 251 9.4E-129 T 14-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 MB46_11240 3f3c176f12aed829d9ea724fa133df08 444 ProSitePatterns PS00104 EPSP synthase signature 1. 97 111 - T 14-10-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 MB46_11240 3f3c176f12aed829d9ea724fa133df08 444 PIRSF PIRSF000505 5 434 2.7E-108 T 14-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 MB46_11240 3f3c176f12aed829d9ea724fa133df08 444 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 13 431 26.8 T 14-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 MB46_01845 f7d3fe1a06bebe04a30583f922d1de15 290 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 5 120 2.1E-37 T 14-10-2018 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 MB46_01845 f7d3fe1a06bebe04a30583f922d1de15 290 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 109 130 1.6E-65 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 MB46_01845 f7d3fe1a06bebe04a30583f922d1de15 290 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 264 282 1.6E-65 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 MB46_01845 f7d3fe1a06bebe04a30583f922d1de15 290 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 74 101 1.6E-65 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 MB46_01845 f7d3fe1a06bebe04a30583f922d1de15 290 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 158 178 1.6E-65 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 MB46_01845 f7d3fe1a06bebe04a30583f922d1de15 290 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 33 55 1.6E-65 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 MB46_01845 f7d3fe1a06bebe04a30583f922d1de15 290 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 209 238 1.6E-65 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 MB46_01845 f7d3fe1a06bebe04a30583f922d1de15 290 SUPERFAMILY SSF51735 122 288 1.62E-39 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_01845 f7d3fe1a06bebe04a30583f922d1de15 290 Hamap MF_01576 Bifunctional protein FolD [folD]. 3 290 35.049 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 MB46_01845 f7d3fe1a06bebe04a30583f922d1de15 290 SUPERFAMILY SSF53223 1 121 4.6E-39 T 14-10-2018 MB46_01845 f7d3fe1a06bebe04a30583f922d1de15 290 Gene3D G3DSA:3.40.50.720 6 267 8.2E-104 T 14-10-2018 MB46_01845 f7d3fe1a06bebe04a30583f922d1de15 290 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 123 289 2.3E-56 T 14-10-2018 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0004488 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 MB46_01845 f7d3fe1a06bebe04a30583f922d1de15 290 Gene3D G3DSA:3.40.50.10860 8 285 8.2E-104 T 14-10-2018 MB46_19325 1951842d778f3e0de6252da7d4969164 391 SUPERFAMILY SSF52540 6 289 2.29E-16 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_19325 1951842d778f3e0de6252da7d4969164 391 Pfam PF13191 AAA ATPase domain 19 197 5.9E-15 T 14-10-2018 MB46_19325 1951842d778f3e0de6252da7d4969164 391 Gene3D G3DSA:3.40.50.300 8 207 4.2E-10 T 14-10-2018 MB46_01420 5c30834a6ce5f6b2405c76fe69551c36 280 SUPERFAMILY SSF51569 5 241 2.93E-56 T 14-10-2018 MB46_01420 5c30834a6ce5f6b2405c76fe69551c36 280 PIRSF PIRSF001359 1 277 7.5E-50 T 14-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 MB46_01420 5c30834a6ce5f6b2405c76fe69551c36 280 Pfam PF01116 Fructose-bisphosphate aldolase class-II 8 247 4.4E-59 T 14-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 MB46_01420 5c30834a6ce5f6b2405c76fe69551c36 280 Gene3D G3DSA:3.20.20.70 3 279 2.6E-63 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MB46_01875 aec22f7f5d85b7dbe48a5299c2a8b3db 435 Gene3D G3DSA:3.30.565.10 266 418 9.0E-17 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MB46_01875 aec22f7f5d85b7dbe48a5299c2a8b3db 435 Pfam PF07730 Histidine kinase 200 262 1.0E-8 T 14-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 MB46_18500 09714b906d0c9e629fd7e105427c47ad 151 SUPERFAMILY SSF55961 5 136 8.79E-16 T 14-10-2018 MB46_18500 09714b906d0c9e629fd7e105427c47ad 151 Gene3D G3DSA:3.30.530.20 22 150 2.6E-12 T 14-10-2018 IPR023393 START-like domain superfamily MB46_16200 5d10c51a66a361602cd3a69ec6447fc9 212 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 5 192 6.7E-62 T 14-10-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MB46_16200 5d10c51a66a361602cd3a69ec6447fc9 212 Gene3D G3DSA:3.40.50.880 3 201 6.1E-61 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like MB46_16200 5d10c51a66a361602cd3a69ec6447fc9 212 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 80 96 6.5E-9 T 14-10-2018 MB46_16200 5d10c51a66a361602cd3a69ec6447fc9 212 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 49 63 6.5E-9 T 14-10-2018 MB46_16200 5d10c51a66a361602cd3a69ec6447fc9 212 PRINTS PR00097 Anthranilate synthase component II signature 5 19 1.8E-34 T 14-10-2018 MB46_16200 5d10c51a66a361602cd3a69ec6447fc9 212 PRINTS PR00097 Anthranilate synthase component II signature 170 183 1.8E-34 T 14-10-2018 MB46_16200 5d10c51a66a361602cd3a69ec6447fc9 212 PRINTS PR00097 Anthranilate synthase component II signature 80 91 1.8E-34 T 14-10-2018 MB46_16200 5d10c51a66a361602cd3a69ec6447fc9 212 PRINTS PR00097 Anthranilate synthase component II signature 125 137 1.8E-34 T 14-10-2018 MB46_16200 5d10c51a66a361602cd3a69ec6447fc9 212 PRINTS PR00097 Anthranilate synthase component II signature 105 113 1.8E-34 T 14-10-2018 MB46_16200 5d10c51a66a361602cd3a69ec6447fc9 212 PRINTS PR00097 Anthranilate synthase component II signature 52 61 1.8E-34 T 14-10-2018 MB46_16200 5d10c51a66a361602cd3a69ec6447fc9 212 Pfam PF00117 Glutamine amidotransferase class-I 6 190 2.2E-52 T 14-10-2018 IPR017926 Glutamine amidotransferase MB46_16200 5d10c51a66a361602cd3a69ec6447fc9 212 PRINTS PR00096 Glutamine amidotransferase superfamily signature 80 91 7.0E-14 T 14-10-2018 MB46_16200 5d10c51a66a361602cd3a69ec6447fc9 212 PRINTS PR00096 Glutamine amidotransferase superfamily signature 52 61 7.0E-14 T 14-10-2018 MB46_16200 5d10c51a66a361602cd3a69ec6447fc9 212 PRINTS PR00096 Glutamine amidotransferase superfamily signature 170 183 7.0E-14 T 14-10-2018 MB46_16200 5d10c51a66a361602cd3a69ec6447fc9 212 SUPERFAMILY SSF52317 3 193 2.52E-54 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like MB46_15470 847720aa094686c3a5957d5c98a2678b 179 ProSitePatterns PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. 95 106 - T 14-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 MB46_15470 847720aa094686c3a5957d5c98a2678b 179 SUPERFAMILY SSF55083 8 155 8.76E-45 T 14-10-2018 IPR035907 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 MB46_15470 847720aa094686c3a5957d5c98a2678b 179 Gene3D G3DSA:3.30.70.560 5 161 4.6E-47 T 14-10-2018 IPR035907 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 MB46_15470 847720aa094686c3a5957d5c98a2678b 179 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 11 139 1.2E-33 T 14-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 MB46_15470 847720aa094686c3a5957d5c98a2678b 179 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 10 139 1.6E-38 T 14-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 MB46_01310 78c34f553ac685384329eecf7de30523 449 Pfam PF07690 Major Facilitator Superfamily 32 400 5.6E-44 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MB46_01310 78c34f553ac685384329eecf7de30523 449 Gene3D G3DSA:1.20.1250.20 5 447 4.2E-67 T 14-10-2018 MB46_01310 78c34f553ac685384329eecf7de30523 449 SUPERFAMILY SSF103473 17 440 9.29E-72 T 14-10-2018 IPR036259 MFS transporter superfamily MB46_05865 d25a4605195f3da3123b997492b33733 190 SUPERFAMILY SSF54909 6 88 1.9E-15 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel MB46_05865 d25a4605195f3da3123b997492b33733 190 Pfam PF03992 Antibiotic biosynthesis monooxygenase 6 76 2.2E-5 T 14-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain MB46_11105 4493115368f129b1e485ff67f69fd6e4 159 TIGRFAM TIGR01950 SoxR: redox-sensitive transcriptional activator SoxR 17 154 6.7E-59 T 14-10-2018 IPR010211 Redox-sensitive transcriptional activator SoxR GO:0003677|GO:0006355|GO:0006979|GO:0051537 MB46_11105 4493115368f129b1e485ff67f69fd6e4 159 SUPERFAMILY SSF46955 17 139 4.4E-25 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily MB46_11105 4493115368f129b1e485ff67f69fd6e4 159 SMART SM00422 17 85 5.1E-20 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MB46_11105 4493115368f129b1e485ff67f69fd6e4 159 Pfam PF00376 MerR family regulatory protein 18 54 9.7E-14 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MB46_11105 4493115368f129b1e485ff67f69fd6e4 159 Gene3D G3DSA:1.10.1660.10 9 140 1.1E-30 T 14-10-2018 MB46_11105 4493115368f129b1e485ff67f69fd6e4 159 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 18 29 1.2E-13 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MB46_11105 4493115368f129b1e485ff67f69fd6e4 159 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 29 42 1.2E-13 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MB46_11105 4493115368f129b1e485ff67f69fd6e4 159 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 52 72 1.2E-13 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MB46_11105 4493115368f129b1e485ff67f69fd6e4 159 Pfam PF09278 MerR, DNA binding 59 123 4.2E-14 T 14-10-2018 IPR015358 Transcription regulator MerR, DNA binding MB46_15030 13b962dd9f261f77132017ccb0f4604a 267 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 1 266 1.3E-77 T 14-10-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 MB46_15030 13b962dd9f261f77132017ccb0f4604a 267 ProSitePatterns PS00726 AP endonucleases family 1 signature 1. 27 36 - T 14-10-2018 IPR020847 AP endonuclease 1, binding site GO:0003677|GO:0004519|GO:0005622|GO:0006281 MB46_15030 13b962dd9f261f77132017ccb0f4604a 267 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 4 259 7.1E-21 T 14-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase MB46_15030 13b962dd9f261f77132017ccb0f4604a 267 SUPERFAMILY SSF56219 2 266 8.64E-71 T 14-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily MB46_15030 13b962dd9f261f77132017ccb0f4604a 267 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 2 266 5.5E-60 T 14-10-2018 MB46_15030 13b962dd9f261f77132017ccb0f4604a 267 Gene3D G3DSA:3.60.10.10 1 266 1.7E-70 T 14-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily MB46_01430 b4d36f0b16594d53cc2beaa8b3c0507f 300 SUPERFAMILY SSF48179 167 292 2.72E-29 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MB46_01430 b4d36f0b16594d53cc2beaa8b3c0507f 300 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 7 161 9.4E-28 T 14-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 MB46_01430 b4d36f0b16594d53cc2beaa8b3c0507f 300 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 9 22 - T 14-10-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 MB46_01430 b4d36f0b16594d53cc2beaa8b3c0507f 300 Gene3D G3DSA:1.10.1040.10 165 297 1.3E-34 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MB46_01430 b4d36f0b16594d53cc2beaa8b3c0507f 300 SUPERFAMILY SSF51735 6 163 9.0E-29 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_01430 b4d36f0b16594d53cc2beaa8b3c0507f 300 PIRSF PIRSF000103 1 300 6.1E-57 T 14-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 MB46_01430 b4d36f0b16594d53cc2beaa8b3c0507f 300 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 168 291 1.1E-29 T 14-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 MB46_01430 b4d36f0b16594d53cc2beaa8b3c0507f 300 Gene3D G3DSA:3.40.50.720 1 164 7.8E-36 T 14-10-2018 MB46_16595 e5a405eb83ca14d2d9721e7a9fc00eef 263 Pfam PF12697 Alpha/beta hydrolase family 24 252 7.1E-17 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MB46_16595 e5a405eb83ca14d2d9721e7a9fc00eef 263 Gene3D G3DSA:3.40.50.1820 2 260 6.8E-54 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_16595 e5a405eb83ca14d2d9721e7a9fc00eef 263 SUPERFAMILY SSF53474 4 262 1.41E-36 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_13300 901dbcf80a89c4cb2c1fe24c0665867b 73 Gene3D G3DSA:2.40.50.140 1 73 3.2E-38 T 14-10-2018 MB46_13300 901dbcf80a89c4cb2c1fe24c0665867b 73 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 2 73 26.187 T 14-10-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 MB46_13300 901dbcf80a89c4cb2c1fe24c0665867b 73 Pfam PF01176 Translation initiation factor 1A / IF-1 8 71 8.7E-29 T 14-10-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 MB46_13300 901dbcf80a89c4cb2c1fe24c0665867b 73 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 4 72 4.8E-37 T 14-10-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 MB46_13300 901dbcf80a89c4cb2c1fe24c0665867b 73 SUPERFAMILY SSF50249 4 72 3.71E-27 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold MB46_05970 081b1da7ede711b18be423db5398a188 183 Gene3D G3DSA:3.40.50.360 2 183 9.1E-40 T 14-10-2018 IPR029039 Flavoprotein-like superfamily MB46_05970 081b1da7ede711b18be423db5398a188 183 Pfam PF03358 NADPH-dependent FMN reductase 3 149 1.2E-31 T 14-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 MB46_05970 081b1da7ede711b18be423db5398a188 183 SUPERFAMILY SSF52218 3 174 2.35E-35 T 14-10-2018 IPR029039 Flavoprotein-like superfamily MB46_02545 69691282e1f06ea80b6cedcd79c52d8f 153 Gene3D G3DSA:3.90.1010.10 1 151 4.1E-41 T 14-10-2018 MB46_02545 69691282e1f06ea80b6cedcd79c52d8f 153 TIGRFAM TIGR01994 SUF_scaf_2: SUF system FeS assembly protein, NifU family 4 149 1.3E-38 T 14-10-2018 MB46_02545 69691282e1f06ea80b6cedcd79c52d8f 153 Pfam PF01592 NifU-like N terminal domain 36 137 1.6E-15 T 14-10-2018 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 MB46_02545 69691282e1f06ea80b6cedcd79c52d8f 153 SUPERFAMILY SSF82649 2 151 6.8E-35 T 14-10-2018 MB46_03850 7719af689dbb5bf0de0cc8981c1634ac 166 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 13 148 3.4E-26 T 14-10-2018 IPR001453 MoaB/Mog domain MB46_03850 7719af689dbb5bf0de0cc8981c1634ac 166 SUPERFAMILY SSF53218 12 160 1.31E-38 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily MB46_03850 7719af689dbb5bf0de0cc8981c1634ac 166 SMART SM00852 14 156 4.8E-19 T 14-10-2018 IPR001453 MoaB/Mog domain MB46_03850 7719af689dbb5bf0de0cc8981c1634ac 166 Gene3D G3DSA:3.40.980.10 9 165 2.0E-49 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily MB46_03850 7719af689dbb5bf0de0cc8981c1634ac 166 Pfam PF00994 Probable molybdopterin binding domain 14 155 1.0E-27 T 14-10-2018 IPR001453 MoaB/Mog domain MB46_10690 2ce5d8a26f721d5fb6185000fb68c94f 332 SUPERFAMILY SSF53098 4 167 1.27E-36 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily MB46_10690 2ce5d8a26f721d5fb6185000fb68c94f 332 Gene3D G3DSA:3.30.420.10 3 177 1.7E-32 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 MB46_10690 2ce5d8a26f721d5fb6185000fb68c94f 332 SUPERFAMILY SSF52113 244 330 8.18E-9 T 14-10-2018 IPR036420 BRCT domain superfamily MB46_10690 2ce5d8a26f721d5fb6185000fb68c94f 332 Pfam PF00929 Exonuclease 7 160 1.5E-15 T 14-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III MB46_10690 2ce5d8a26f721d5fb6185000fb68c94f 332 Gene3D G3DSA:3.40.50.10190 228 332 3.0E-17 T 14-10-2018 IPR036420 BRCT domain superfamily MB46_10690 2ce5d8a26f721d5fb6185000fb68c94f 332 SMART SM00479 4 170 2.1E-14 T 14-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III MB46_15430 5d71af1f476825f93113b2effa8e83e2 319 Gene3D G3DSA:3.90.245.10 5 318 2.3E-125 T 14-10-2018 IPR036452 Ribonucleoside hydrolase-like MB46_15430 5d71af1f476825f93113b2effa8e83e2 319 ProSitePatterns PS01247 Inosine-uridine preferring nucleoside hydrolase family signature. 12 22 - T 14-10-2018 IPR015910 Inosine/uridine-preferring nucleoside hydrolase, conserved site GO:0016799 MB46_15430 5d71af1f476825f93113b2effa8e83e2 319 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 7 305 6.5E-93 T 14-10-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain MB46_15430 5d71af1f476825f93113b2effa8e83e2 319 SUPERFAMILY SSF53590 6 314 1.57E-105 T 14-10-2018 IPR036452 Ribonucleoside hydrolase-like MB46_05685 9d4351b6b18a1b35d620bad64e0322ad 204 Pfam PF01810 LysE type translocator 13 201 3.7E-7 T 14-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 MB46_06135 7acf9874337278e553c610662b37a563 495 TIGRFAM TIGR01722 MMSDH: methylmalonate-semialdehyde dehydrogenase (acylating) 5 479 6.8E-205 T 14-10-2018 IPR010061 Methylmalonate-semialdehyde dehydrogenase GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00640+1.2.1.27|MetaCyc: PWY-5642|Reactome: R-HSA-70895 MB46_06135 7acf9874337278e553c610662b37a563 495 Pfam PF00171 Aldehyde dehydrogenase family 14 475 2.8E-144 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 MB46_06135 7acf9874337278e553c610662b37a563 495 SUPERFAMILY SSF53720 3 479 3.53E-149 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 MB46_06135 7acf9874337278e553c610662b37a563 495 Gene3D G3DSA:3.40.605.10 22 456 1.0E-149 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 MB46_06135 7acf9874337278e553c610662b37a563 495 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 273 284 - T 14-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 MB46_06135 7acf9874337278e553c610662b37a563 495 Gene3D G3DSA:3.40.309.10 248 448 1.0E-149 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 MB46_11915 95c808b031e28017d8761b716603aa53 488 Gene3D G3DSA:3.30.870.10 115 299 4.6E-37 T 14-10-2018 MB46_11915 95c808b031e28017d8761b716603aa53 488 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 15 487 1.4E-94 T 14-10-2018 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 MB46_11915 95c808b031e28017d8761b716603aa53 488 Pfam PF13396 Phospholipase_D-nuclease N-terminal 24 61 1.1E-5 T 14-10-2018 IPR027379 Cardiolipin synthase N-terminal MB46_11915 95c808b031e28017d8761b716603aa53 488 Gene3D G3DSA:3.30.870.10 300 487 3.3E-24 T 14-10-2018 MB46_11915 95c808b031e28017d8761b716603aa53 488 SUPERFAMILY SSF56024 276 472 2.47E-42 T 14-10-2018 MB46_11915 95c808b031e28017d8761b716603aa53 488 SMART SM00155 220 247 0.052 T 14-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 MB46_11915 95c808b031e28017d8761b716603aa53 488 SMART SM00155 401 428 0.068 T 14-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 MB46_11915 95c808b031e28017d8761b716603aa53 488 Pfam PF13091 PLD-like domain 135 283 2.1E-14 T 14-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 MB46_11915 95c808b031e28017d8761b716603aa53 488 Pfam PF13091 PLD-like domain 328 449 4.4E-24 T 14-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 MB46_11915 95c808b031e28017d8761b716603aa53 488 SUPERFAMILY SSF56024 103 316 9.42E-46 T 14-10-2018 MB46_07610 aad2e5261cb590175bc830d52ca6d847 495 Gene3D G3DSA:2.40.33.10 70 167 4.6E-168 T 14-10-2018 IPR015806 Pyruvate kinase, insert domain superfamily GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MB46_07610 aad2e5261cb590175bc830d52ca6d847 495 PRINTS PR01050 Pyruvate kinase family signature 59 75 2.9E-66 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MB46_07610 aad2e5261cb590175bc830d52ca6d847 495 PRINTS PR01050 Pyruvate kinase family signature 311 327 2.9E-66 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MB46_07610 aad2e5261cb590175bc830d52ca6d847 495 PRINTS PR01050 Pyruvate kinase family signature 185 199 2.9E-66 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MB46_07610 aad2e5261cb590175bc830d52ca6d847 495 PRINTS PR01050 Pyruvate kinase family signature 267 291 2.9E-66 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MB46_07610 aad2e5261cb590175bc830d52ca6d847 495 PRINTS PR01050 Pyruvate kinase family signature 242 266 2.9E-66 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MB46_07610 aad2e5261cb590175bc830d52ca6d847 495 PRINTS PR01050 Pyruvate kinase family signature 292 310 2.9E-66 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MB46_07610 aad2e5261cb590175bc830d52ca6d847 495 PRINTS PR01050 Pyruvate kinase family signature 215 241 2.9E-66 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MB46_07610 aad2e5261cb590175bc830d52ca6d847 495 SUPERFAMILY SSF52935 321 470 1.7E-39 T 14-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MB46_07610 aad2e5261cb590175bc830d52ca6d847 495 Pfam PF02887 Pyruvate kinase, alpha/beta domain 356 467 1.7E-30 T 14-10-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MB46_07610 aad2e5261cb590175bc830d52ca6d847 495 SUPERFAMILY SSF50800 70 165 3.66E-25 T 14-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily MB46_07610 aad2e5261cb590175bc830d52ca6d847 495 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 2 469 5.1E-165 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MB46_07610 aad2e5261cb590175bc830d52ca6d847 495 SUPERFAMILY SSF51621 1 336 6.98E-94 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 MB46_07610 aad2e5261cb590175bc830d52ca6d847 495 Pfam PF00224 Pyruvate kinase, barrel domain 2 335 2.0E-121 T 14-10-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MB46_07610 aad2e5261cb590175bc830d52ca6d847 495 ProSitePatterns PS00110 Pyruvate kinase active site signature. 213 225 - T 14-10-2018 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MB46_07610 aad2e5261cb590175bc830d52ca6d847 495 Gene3D G3DSA:3.40.1380.20 334 465 4.6E-168 T 14-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MB46_07610 aad2e5261cb590175bc830d52ca6d847 495 Gene3D G3DSA:3.20.20.60 2 333 4.6E-168 T 14-10-2018 MB46_04235 adf4cab6629eefba2a0d00c549d092b8 162 Gene3D G3DSA:3.30.530.20 19 159 1.4E-20 T 14-10-2018 IPR023393 START-like domain superfamily MB46_04235 adf4cab6629eefba2a0d00c549d092b8 162 SUPERFAMILY SSF55961 25 155 1.57E-15 T 14-10-2018 MB46_04235 adf4cab6629eefba2a0d00c549d092b8 162 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 29 144 2.0E-5 T 14-10-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like MB46_08665 62931f1cc688c0e6e7e739fa3c45581f 342 Gene3D G3DSA:1.10.8.60 179 252 1.9E-24 T 14-10-2018 MB46_08665 62931f1cc688c0e6e7e739fa3c45581f 342 Gene3D G3DSA:3.40.50.300 17 178 7.3E-38 T 14-10-2018 MB46_08665 62931f1cc688c0e6e7e739fa3c45581f 342 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 250 324 6.6E-29 T 14-10-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 MB46_08665 62931f1cc688c0e6e7e739fa3c45581f 342 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 4 231 4.9E-103 T 14-10-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 MB46_08665 62931f1cc688c0e6e7e739fa3c45581f 342 SUPERFAMILY SSF52540 17 248 6.68E-51 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_08665 62931f1cc688c0e6e7e739fa3c45581f 342 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 342 148.745 T 14-10-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 MB46_08665 62931f1cc688c0e6e7e739fa3c45581f 342 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 247 327 3.0E-22 T 14-10-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 MB46_08665 62931f1cc688c0e6e7e739fa3c45581f 342 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 20 323 2.1E-128 T 14-10-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 MB46_08665 62931f1cc688c0e6e7e739fa3c45581f 342 SMART SM00382 48 181 1.5E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_08665 62931f1cc688c0e6e7e739fa3c45581f 342 Gene3D G3DSA:1.10.10.10 254 334 1.5E-30 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_08665 62931f1cc688c0e6e7e739fa3c45581f 342 SUPERFAMILY SSF46785 254 327 2.63E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_03940 19148baeb6d3120c5c1958b86537f907 212 Pfam PF05175 Methyltransferase small domain 33 189 5.6E-28 T 14-10-2018 IPR007848 Methyltransferase small domain GO:0008168 MB46_03940 19148baeb6d3120c5c1958b86537f907 212 SUPERFAMILY SSF53335 33 195 2.26E-27 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MB46_03940 19148baeb6d3120c5c1958b86537f907 212 Gene3D G3DSA:3.40.50.150 10 207 2.8E-34 T 14-10-2018 MB46_03125 f666ccb75a2d916c3f9728ef8f6440d1 1794 SMART SM00776 1435 1586 1.9E-39 T 14-10-2018 IPR013222 Glycosyl hydrolase family 98, putative carbohydrate-binding module MB46_03125 f666ccb75a2d916c3f9728ef8f6440d1 1794 SMART SM00776 1187 1332 2.9E-50 T 14-10-2018 IPR013222 Glycosyl hydrolase family 98, putative carbohydrate-binding module MB46_03125 f666ccb75a2d916c3f9728ef8f6440d1 1794 Gene3D G3DSA:2.70.98.10 38 301 5.2E-69 T 14-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 MB46_03125 f666ccb75a2d916c3f9728ef8f6440d1 1794 Gene3D G3DSA:2.60.120.260 890 1067 5.5E-57 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily MB46_03125 f666ccb75a2d916c3f9728ef8f6440d1 1794 SUPERFAMILY SSF49785 1438 1588 3.66E-32 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily MB46_03125 f666ccb75a2d916c3f9728ef8f6440d1 1794 Pfam PF12905 Endo-alpha-N-acetylgalactosaminidase 290 562 1.5E-111 T 14-10-2018 IPR025706 Endo-alpha-N-acetylgalactosaminidase GO:0033926 MB46_03125 f666ccb75a2d916c3f9728ef8f6440d1 1794 Gene3D G3DSA:3.20.20.80 303 578 5.7E-103 T 14-10-2018 MB46_03125 f666ccb75a2d916c3f9728ef8f6440d1 1794 Pfam PF17451 Glycosyl hydrolase 101 beta sandwich domain 568 678 8.6E-24 T 14-10-2018 IPR035364 Glycosyl hydrolase 101, beta-sandwich domain MB46_03125 f666ccb75a2d916c3f9728ef8f6440d1 1794 Pfam PF08305 NPCBM/NEW2 domain 1190 1330 1.0E-42 T 14-10-2018 IPR013222 Glycosyl hydrolase family 98, putative carbohydrate-binding module MB46_03125 f666ccb75a2d916c3f9728ef8f6440d1 1794 Pfam PF08305 NPCBM/NEW2 domain 1438 1584 1.6E-37 T 14-10-2018 IPR013222 Glycosyl hydrolase family 98, putative carbohydrate-binding module MB46_03125 f666ccb75a2d916c3f9728ef8f6440d1 1794 Gene3D G3DSA:2.60.120.1060 1433 1585 5.5E-35 T 14-10-2018 IPR038637 NPCBM domain superfamily MB46_03125 f666ccb75a2d916c3f9728ef8f6440d1 1794 Gene3D G3DSA:2.60.120.1060 1187 1330 4.8E-41 T 14-10-2018 IPR038637 NPCBM domain superfamily MB46_03125 f666ccb75a2d916c3f9728ef8f6440d1 1794 Pfam PF10633 NPCBM-associated, NEW3 domain of alpha-galactosidase 1087 1159 7.4E-16 T 14-10-2018 IPR018905 Alpha-galactosidase, NEW3 domain MB46_03125 f666ccb75a2d916c3f9728ef8f6440d1 1794 SUPERFAMILY SSF49785 1190 1334 2.76E-39 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily MB46_03125 f666ccb75a2d916c3f9728ef8f6440d1 1794 Gene3D G3DSA:2.60.120.260 727 885 1.3E-31 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily MB46_04785 e943b828728b2853b635a126caa499be 515 Pfam PF00196 Bacterial regulatory proteins, luxR family 448 503 5.1E-17 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_04785 e943b828728b2853b635a126caa499be 515 SUPERFAMILY SSF109604 13 222 7.49E-7 T 14-10-2018 MB46_04785 e943b828728b2853b635a126caa499be 515 Gene3D G3DSA:1.10.10.10 440 513 2.4E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_04785 e943b828728b2853b635a126caa499be 515 Gene3D G3DSA:1.10.3210.10 99 229 2.3E-16 T 14-10-2018 MB46_04785 e943b828728b2853b635a126caa499be 515 Gene3D G3DSA:1.10.3210.10 253 437 3.6E-35 T 14-10-2018 MB46_04785 e943b828728b2853b635a126caa499be 515 SUPERFAMILY SSF109604 267 410 9.11E-16 T 14-10-2018 MB46_04785 e943b828728b2853b635a126caa499be 515 Pfam PF13487 HD domain 328 386 6.3E-17 T 14-10-2018 MB46_04785 e943b828728b2853b635a126caa499be 515 Pfam PF13487 HD domain 127 181 5.5E-9 T 14-10-2018 MB46_04785 e943b828728b2853b635a126caa499be 515 SMART SM00421 446 503 4.9E-20 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_04785 e943b828728b2853b635a126caa499be 515 SUPERFAMILY SSF46894 442 509 7.82E-19 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MB46_04785 e943b828728b2853b635a126caa499be 515 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 449 463 8.1E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_04785 e943b828728b2853b635a126caa499be 515 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 463 479 8.1E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_04785 e943b828728b2853b635a126caa499be 515 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 479 491 8.1E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_08350 22594d0f01ecabdcdbf0e30751d956ff 604 ProSitePatterns PS00455 Putative AMP-binding domain signature. 186 197 - T 14-10-2018 IPR020845 AMP-binding, conserved site MB46_08350 22594d0f01ecabdcdbf0e30751d956ff 604 Gene3D G3DSA:3.40.50.12780 323 461 3.7E-37 T 14-10-2018 MB46_08350 22594d0f01ecabdcdbf0e30751d956ff 604 SUPERFAMILY SSF56801 13 598 7.72E-113 T 14-10-2018 MB46_08350 22594d0f01ecabdcdbf0e30751d956ff 604 Gene3D G3DSA:3.40.50.12780 8 321 2.8E-52 T 14-10-2018 MB46_08350 22594d0f01ecabdcdbf0e30751d956ff 604 Pfam PF00501 AMP-binding enzyme 31 468 4.8E-97 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 MB46_19600 09600d40304d600545c1c8aec419a8d6 153 Gene3D G3DSA:2.40.50.140 2 121 4.9E-19 T 14-10-2018 MB46_19600 09600d40304d600545c1c8aec419a8d6 153 SUPERFAMILY SSF50249 7 137 2.26E-12 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold MB46_19600 09600d40304d600545c1c8aec419a8d6 153 Pfam PF00436 Single-strand binding protein family 7 107 1.0E-8 T 14-10-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 MB46_13835 f9585e7cbb300eaba7a8e0ddf1a0f4a7 488 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 15 433 2.9E-76 T 14-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 MB46_13835 f9585e7cbb300eaba7a8e0ddf1a0f4a7 488 Gene3D G3DSA:1.20.1720.10 16 227 1.2E-50 T 14-10-2018 MB46_13835 f9585e7cbb300eaba7a8e0ddf1a0f4a7 488 Gene3D G3DSA:1.20.1250.20 264 475 4.4E-16 T 14-10-2018 MB46_13835 f9585e7cbb300eaba7a8e0ddf1a0f4a7 488 PRINTS PR01036 Tetracycline resistance protein TetB signature 412 431 3.3E-6 T 14-10-2018 MB46_13835 f9585e7cbb300eaba7a8e0ddf1a0f4a7 488 PRINTS PR01036 Tetracycline resistance protein TetB signature 109 129 3.3E-6 T 14-10-2018 MB46_13835 f9585e7cbb300eaba7a8e0ddf1a0f4a7 488 PRINTS PR01036 Tetracycline resistance protein TetB signature 18 42 3.3E-6 T 14-10-2018 MB46_13835 f9585e7cbb300eaba7a8e0ddf1a0f4a7 488 PRINTS PR01036 Tetracycline resistance protein TetB signature 208 226 3.3E-6 T 14-10-2018 MB46_13835 f9585e7cbb300eaba7a8e0ddf1a0f4a7 488 Pfam PF07690 Major Facilitator Superfamily 19 421 1.6E-48 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MB46_13835 f9585e7cbb300eaba7a8e0ddf1a0f4a7 488 SUPERFAMILY SSF103473 5 474 8.89E-70 T 14-10-2018 IPR036259 MFS transporter superfamily MB46_15155 ee275a573ee42ba3628709ab96a4f0a6 317 PIRSF PIRSF036979 48 317 1.1E-24 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 MB46_15155 ee275a573ee42ba3628709ab96a4f0a6 317 Hamap MF_00737 Formimidoylglutamase [hutG]. 10 317 38.772 T 14-10-2018 IPR005923 Formiminoglutamase GO:0019556|GO:0050415 KEGG: 00340+3.5.3.8 MB46_15155 ee275a573ee42ba3628709ab96a4f0a6 317 SUPERFAMILY SSF52768 15 316 3.6E-69 T 14-10-2018 IPR023696 Ureohydrolase domain superfamily MB46_15155 ee275a573ee42ba3628709ab96a4f0a6 317 ProSitePatterns PS01053 Arginase family signature. 246 267 - T 14-10-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 MB46_15155 ee275a573ee42ba3628709ab96a4f0a6 317 TIGRFAM TIGR01227 hutG: formimidoylglutamase 15 316 7.7E-85 T 14-10-2018 IPR005923 Formiminoglutamase GO:0019556|GO:0050415 KEGG: 00340+3.5.3.8 MB46_15155 ee275a573ee42ba3628709ab96a4f0a6 317 Gene3D G3DSA:3.40.800.10 9 317 2.5E-93 T 14-10-2018 MB46_15155 ee275a573ee42ba3628709ab96a4f0a6 317 PRINTS PR00116 Arginase signature 128 143 3.5E-6 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 MB46_15155 ee275a573ee42ba3628709ab96a4f0a6 317 PRINTS PR00116 Arginase signature 243 272 3.5E-6 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 MB46_15155 ee275a573ee42ba3628709ab96a4f0a6 317 PRINTS PR00116 Arginase signature 278 292 3.5E-6 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 MB46_15155 ee275a573ee42ba3628709ab96a4f0a6 317 Pfam PF00491 Arginase family 49 315 6.6E-52 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 MB46_02960 11c9e8f4d00145a115c5a610cd6ba6c1 1478 Pfam PF16697 Inner membrane component of T3SS, cytoplasmic domain 108 194 2.5E-14 T 14-10-2018 IPR032030 YscD, cytoplasmic domain MB46_02960 11c9e8f4d00145a115c5a610cd6ba6c1 1478 SMART SM00240 125 174 1.9E-4 T 14-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 MB46_02960 11c9e8f4d00145a115c5a610cd6ba6c1 1478 Gene3D G3DSA:3.40.50.300 978 1260 1.3E-55 T 14-10-2018 MB46_02960 11c9e8f4d00145a115c5a610cd6ba6c1 1478 SMART SM00382 1012 1188 8.8E-5 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_02960 11c9e8f4d00145a115c5a610cd6ba6c1 1478 SMART SM00382 687 864 0.18 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_02960 11c9e8f4d00145a115c5a610cd6ba6c1 1478 SMART SM00382 1290 1435 6.7 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_02960 11c9e8f4d00145a115c5a610cd6ba6c1 1478 Gene3D G3DSA:3.40.50.300 383 585 1.2E-14 T 14-10-2018 MB46_02960 11c9e8f4d00145a115c5a610cd6ba6c1 1478 Pfam PF01580 FtsK/SpoIIIE family 1001 1192 3.3E-21 T 14-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 MB46_02960 11c9e8f4d00145a115c5a610cd6ba6c1 1478 Pfam PF01580 FtsK/SpoIIIE family 661 867 1.3E-30 T 14-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 MB46_02960 11c9e8f4d00145a115c5a610cd6ba6c1 1478 SUPERFAMILY SSF52540 963 1187 5.72E-16 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_02960 11c9e8f4d00145a115c5a610cd6ba6c1 1478 Gene3D G3DSA:2.60.200.20 85 197 1.6E-19 T 14-10-2018 MB46_02960 11c9e8f4d00145a115c5a610cd6ba6c1 1478 Gene3D G3DSA:3.40.50.300 648 917 7.9E-74 T 14-10-2018 MB46_02960 11c9e8f4d00145a115c5a610cd6ba6c1 1478 SUPERFAMILY SSF52540 676 869 1.85E-25 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_02960 11c9e8f4d00145a115c5a610cd6ba6c1 1478 SUPERFAMILY SSF49879 89 195 3.06E-17 T 14-10-2018 IPR008984 SMAD/FHA domain superfamily GO:0005515 MB46_01655 c66ca136262a5c2e5650320212ef9051 595 PIRSF PIRSF002741 1 537 6.5E-94 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 MB46_01655 c66ca136262a5c2e5650320212ef9051 595 Gene3D G3DSA:3.10.105.10 289 509 2.4E-51 T 14-10-2018 MB46_01655 c66ca136262a5c2e5650320212ef9051 595 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 77 446 1.5E-85 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain MB46_01655 c66ca136262a5c2e5650320212ef9051 595 Gene3D G3DSA:3.40.190.10 4 275 1.4E-68 T 14-10-2018 MB46_01655 c66ca136262a5c2e5650320212ef9051 595 SUPERFAMILY SSF53850 27 526 9.42E-122 T 14-10-2018 MB46_15325 fcb1e526b5b4835df84c0397b99b7e70 368 SUPERFAMILY SSF161098 85 354 2.09E-37 T 14-10-2018 IPR035906 MetI-like superfamily MB46_15325 fcb1e526b5b4835df84c0397b99b7e70 368 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 75 362 9.5E-84 T 14-10-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 MB46_15325 fcb1e526b5b4835df84c0397b99b7e70 368 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 159 366 1.6E-25 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_15325 fcb1e526b5b4835df84c0397b99b7e70 368 Gene3D G3DSA:1.10.3720.10 136 363 9.1E-33 T 14-10-2018 IPR035906 MetI-like superfamily MB46_06515 acf41055a54551ddf84860c264adeafe 538 Gene3D G3DSA:3.40.50.970 1 178 2.5E-51 T 14-10-2018 MB46_06515 acf41055a54551ddf84860c264adeafe 538 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 416 435 - T 14-10-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 MB46_06515 acf41055a54551ddf84860c264adeafe 538 Gene3D G3DSA:3.40.50.970 356 537 7.4E-51 T 14-10-2018 MB46_06515 acf41055a54551ddf84860c264adeafe 538 SUPERFAMILY SSF52467 155 341 2.77E-27 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily MB46_06515 acf41055a54551ddf84860c264adeafe 538 SUPERFAMILY SSF52518 3 180 9.49E-46 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold MB46_06515 acf41055a54551ddf84860c264adeafe 538 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 191 319 9.8E-17 T 14-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 MB46_06515 acf41055a54551ddf84860c264adeafe 538 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 5 166 4.8E-46 T 14-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 MB46_06515 acf41055a54551ddf84860c264adeafe 538 Gene3D G3DSA:3.40.50.1220 183 343 2.3E-22 T 14-10-2018 MB46_06515 acf41055a54551ddf84860c264adeafe 538 SUPERFAMILY SSF52518 358 534 4.05E-53 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold MB46_06515 acf41055a54551ddf84860c264adeafe 538 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 380 525 3.9E-39 T 14-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 MB46_14920 b71fb5c30447cd6a670dcf8eea09c8bc 268 SUPERFAMILY SSF56317 1 256 2.22E-68 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily MB46_14920 b71fb5c30447cd6a670dcf8eea09c8bc 268 Pfam PF00795 Carbon-nitrogen hydrolase 2 247 4.2E-51 T 14-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 MB46_14920 b71fb5c30447cd6a670dcf8eea09c8bc 268 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 144 164 - T 14-10-2018 IPR001110 Uncharacterised protein family UPF0012, conserved site MB46_14920 b71fb5c30447cd6a670dcf8eea09c8bc 268 Gene3D G3DSA:3.60.110.10 1 265 7.8E-76 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily MB46_06520 e83e38fe5b8c4bf99b5ef81252a9bf82 468 Gene3D G3DSA:3.40.309.10 248 432 2.9E-158 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 MB46_06520 e83e38fe5b8c4bf99b5ef81252a9bf82 468 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 244 251 - T 14-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 MB46_06520 e83e38fe5b8c4bf99b5ef81252a9bf82 468 Gene3D G3DSA:3.40.605.10 22 457 2.9E-158 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 MB46_06520 e83e38fe5b8c4bf99b5ef81252a9bf82 468 SUPERFAMILY SSF53720 2 465 1.44E-152 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 MB46_06520 e83e38fe5b8c4bf99b5ef81252a9bf82 468 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 272 283 - T 14-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 MB46_06520 e83e38fe5b8c4bf99b5ef81252a9bf82 468 Pfam PF00171 Aldehyde dehydrogenase family 17 463 2.2E-153 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 MB46_01725 381937ba616aaa24777cc786558ed6b6 285 SUPERFAMILY SSF52540 31 279 4.82E-63 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_01725 381937ba616aaa24777cc786558ed6b6 285 SMART SM00382 56 256 8.8E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_01725 381937ba616aaa24777cc786558ed6b6 285 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 256 278 1.3E-6 T 14-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal MB46_01725 381937ba616aaa24777cc786558ed6b6 285 Gene3D G3DSA:3.40.50.300 27 279 2.7E-63 T 14-10-2018 MB46_01725 381937ba616aaa24777cc786558ed6b6 285 Pfam PF00005 ABC transporter 47 207 7.7E-34 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_18985 a2b7fae3a29c2a657a5eb6e1a5b883f7 367 Pfam PF08402 TOBE domain 279 315 2.0E-6 T 14-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 MB46_18985 a2b7fae3a29c2a657a5eb6e1a5b883f7 367 Pfam PF00005 ABC transporter 27 171 3.1E-34 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_18985 a2b7fae3a29c2a657a5eb6e1a5b883f7 367 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_18985 a2b7fae3a29c2a657a5eb6e1a5b883f7 367 SUPERFAMILY SSF50331 250 318 1.02E-7 T 14-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal MB46_18985 a2b7fae3a29c2a657a5eb6e1a5b883f7 367 SMART SM00382 36 221 8.8E-22 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_18985 a2b7fae3a29c2a657a5eb6e1a5b883f7 367 Gene3D G3DSA:3.40.50.300 10 256 3.8E-73 T 14-10-2018 MB46_18985 a2b7fae3a29c2a657a5eb6e1a5b883f7 367 SUPERFAMILY SSF52540 12 247 2.93E-73 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_15180 144f3317716667b327ae1c1868a4e1df 523 Gene3D G3DSA:1.20.200.10 205 520 4.6E-108 T 14-10-2018 MB46_15180 144f3317716667b327ae1c1868a4e1df 523 SUPERFAMILY SSF48557 5 512 5.26E-173 T 14-10-2018 IPR008948 L-Aspartase-like GO:0003824 MB46_15180 144f3317716667b327ae1c1868a4e1df 523 Gene3D G3DSA:1.10.275.10 2 204 8.1E-64 T 14-10-2018 IPR024083 Fumarase/histidase, N-terminal MB46_15180 144f3317716667b327ae1c1868a4e1df 523 ProSitePatterns PS00488 Phenylalanine and histidine ammonia-lyases signature. 145 161 - T 14-10-2018 IPR022313 Phenylalanine/histidine ammonia-lyases, active site GO:0016841 Reactome: R-HSA-70921 MB46_15180 144f3317716667b327ae1c1868a4e1df 523 TIGRFAM TIGR01225 hutH: histidine ammonia-lyase 10 518 2.1E-194 T 14-10-2018 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 MB46_15180 144f3317716667b327ae1c1868a4e1df 523 Pfam PF00221 Aromatic amino acid lyase 18 483 6.2E-174 T 14-10-2018 IPR001106 Aromatic amino acid lyase Reactome: R-HSA-70921 MB46_19350 9ef772d0137157052c15c0ef3ba45102 83 Gene3D G3DSA:3.90.1680.10 1 82 5.2E-14 T 14-10-2018 IPR036590 SOS response associated peptidase-like MB46_19350 9ef772d0137157052c15c0ef3ba45102 83 SUPERFAMILY SSF143081 2 78 3.79E-12 T 14-10-2018 IPR036590 SOS response associated peptidase-like MB46_19350 9ef772d0137157052c15c0ef3ba45102 83 Pfam PF02586 SOS response associated peptidase (SRAP) 2 65 1.7E-10 T 14-10-2018 IPR003738 SOS response associated peptidase (SRAP) MB46_06565 cbd8241b4b828eea706ac3e8053763da 336 Gene3D G3DSA:3.40.50.2300 159 292 6.1E-67 T 14-10-2018 MB46_06565 cbd8241b4b828eea706ac3e8053763da 336 Pfam PF00356 Bacterial regulatory proteins, lacI family 1 47 9.7E-16 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MB46_06565 cbd8241b4b828eea706ac3e8053763da 336 SUPERFAMILY SSF53822 70 330 4.53E-63 T 14-10-2018 IPR028082 Periplasmic binding protein-like I MB46_06565 cbd8241b4b828eea706ac3e8053763da 336 Gene3D G3DSA:1.10.260.40 1 57 8.2E-18 T 14-10-2018 MB46_06565 cbd8241b4b828eea706ac3e8053763da 336 ProSitePatterns PS00356 LacI-type HTH domain signature. 1 19 - T 14-10-2018 MB46_06565 cbd8241b4b828eea706ac3e8053763da 336 SMART SM00354 1 70 6.4E-16 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MB46_06565 cbd8241b4b828eea706ac3e8053763da 336 Pfam PF13377 Periplasmic binding protein-like domain 168 329 7.6E-36 T 14-10-2018 MB46_06565 cbd8241b4b828eea706ac3e8053763da 336 Gene3D G3DSA:3.40.50.2300 70 312 6.1E-67 T 14-10-2018 MB46_06565 cbd8241b4b828eea706ac3e8053763da 336 SUPERFAMILY SSF47413 1 55 5.14E-13 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MB46_09340 1d91758202cdc9f28abf7ccc2ef4f7ef 190 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 9 166 5.4E-41 T 14-10-2018 IPR023635 Peptide deformylase MB46_09340 1d91758202cdc9f28abf7ccc2ef4f7ef 190 Hamap MF_00163 Peptide deformylase [def]. 2 170 28.393 T 14-10-2018 IPR023635 Peptide deformylase MB46_09340 1d91758202cdc9f28abf7ccc2ef4f7ef 190 PIRSF PIRSF004749 1 176 2.0E-47 T 14-10-2018 IPR023635 Peptide deformylase MB46_09340 1d91758202cdc9f28abf7ccc2ef4f7ef 190 Pfam PF01327 Polypeptide deformylase 4 157 1.8E-46 T 14-10-2018 IPR023635 Peptide deformylase MB46_09340 1d91758202cdc9f28abf7ccc2ef4f7ef 190 SUPERFAMILY SSF56420 1 164 1.19E-53 T 14-10-2018 IPR036821 Peptide deformylase superfamily MB46_09340 1d91758202cdc9f28abf7ccc2ef4f7ef 190 PRINTS PR01576 Peptide deformylase signature 97 108 4.0E-34 T 14-10-2018 IPR023635 Peptide deformylase MB46_09340 1d91758202cdc9f28abf7ccc2ef4f7ef 190 PRINTS PR01576 Peptide deformylase signature 33 62 4.0E-34 T 14-10-2018 IPR023635 Peptide deformylase MB46_09340 1d91758202cdc9f28abf7ccc2ef4f7ef 190 PRINTS PR01576 Peptide deformylase signature 109 127 4.0E-34 T 14-10-2018 IPR023635 Peptide deformylase MB46_09340 1d91758202cdc9f28abf7ccc2ef4f7ef 190 PRINTS PR01576 Peptide deformylase signature 128 157 4.0E-34 T 14-10-2018 IPR023635 Peptide deformylase MB46_09340 1d91758202cdc9f28abf7ccc2ef4f7ef 190 Gene3D G3DSA:3.90.45.10 1 190 5.6E-66 T 14-10-2018 IPR036821 Peptide deformylase superfamily MB46_03575 e1e7c86755426f59401f80078ca4fec1 457 SUPERFAMILY SSF51230 1 87 5.63E-24 T 14-10-2018 IPR011053 Single hybrid motif MB46_03575 e1e7c86755426f59401f80078ca4fec1 457 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 227 453 1.9E-74 T 14-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 MB46_03575 e1e7c86755426f59401f80078ca4fec1 457 Gene3D G3DSA:3.30.559.10 214 455 5.5E-76 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 MB46_03575 e1e7c86755426f59401f80078ca4fec1 457 Gene3D G3DSA:2.40.50.100 2 78 1.5E-21 T 14-10-2018 MB46_03575 e1e7c86755426f59401f80078ca4fec1 457 SUPERFAMILY SSF52777 221 454 2.15E-74 T 14-10-2018 MB46_03575 e1e7c86755426f59401f80078ca4fec1 457 Gene3D G3DSA:4.10.320.10 153 204 4.7E-11 T 14-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 MB46_03575 e1e7c86755426f59401f80078ca4fec1 457 Pfam PF00364 Biotin-requiring enzyme 4 75 9.9E-20 T 14-10-2018 IPR000089 Biotin/lipoyl attachment MB46_03575 e1e7c86755426f59401f80078ca4fec1 457 Pfam PF02817 e3 binding domain 161 194 4.3E-10 T 14-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 MB46_03575 e1e7c86755426f59401f80078ca4fec1 457 SUPERFAMILY SSF47005 157 198 4.71E-9 T 14-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 MB46_03575 e1e7c86755426f59401f80078ca4fec1 457 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 14-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 MB46_00580 8c6a9973d5569b164b0c3a3b6d340d8a 187 SUPERFAMILY SSF47240 4 151 4.33E-27 T 14-10-2018 IPR009078 Ferritin-like superfamily MB46_00580 8c6a9973d5569b164b0c3a3b6d340d8a 187 Pfam PF05974 Domain of unknown function (DUF892) 7 162 2.5E-31 T 14-10-2018 IPR010287 Domain of unknown function DUF892 MB46_00580 8c6a9973d5569b164b0c3a3b6d340d8a 187 Gene3D G3DSA:1.20.1260.10 1 166 4.6E-30 T 14-10-2018 IPR012347 Ferritin-like MB46_12530 d02a27d0c05825af0d02546347e0756b 573 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 250 290 6.2E-8 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MB46_12530 d02a27d0c05825af0d02546347e0756b 573 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 542 567 0.0014 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MB46_12530 d02a27d0c05825af0d02546347e0756b 573 Pfam PF00005 ABC transporter 42 199 1.5E-26 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_12530 d02a27d0c05825af0d02546347e0756b 573 Pfam PF00005 ABC transporter 339 490 1.0E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_12530 d02a27d0c05825af0d02546347e0756b 573 ProSitePatterns PS00211 ABC transporters family signature. 171 185 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_12530 d02a27d0c05825af0d02546347e0756b 573 Gene3D G3DSA:3.40.50.300 312 571 8.3E-84 T 14-10-2018 MB46_12530 d02a27d0c05825af0d02546347e0756b 573 Gene3D G3DSA:3.40.50.300 19 305 8.5E-82 T 14-10-2018 MB46_12530 d02a27d0c05825af0d02546347e0756b 573 ProSitePatterns PS00211 ABC transporters family signature. 463 477 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_12530 d02a27d0c05825af0d02546347e0756b 573 SMART SM00382 348 540 2.6E-17 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_12530 d02a27d0c05825af0d02546347e0756b 573 SMART SM00382 50 248 5.2E-18 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_12530 d02a27d0c05825af0d02546347e0756b 573 SUPERFAMILY SSF52540 314 562 9.02E-74 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_12530 d02a27d0c05825af0d02546347e0756b 573 SUPERFAMILY SSF52540 21 270 8.38E-64 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_12415 1f01a9b21f1cf1a622fd10f3af40ec9d 189 Gene3D G3DSA:1.10.340.30 7 186 3.0E-68 T 14-10-2018 MB46_12415 1f01a9b21f1cf1a622fd10f3af40ec9d 189 SUPERFAMILY SSF48150 7 184 1.26E-63 T 14-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 MB46_12415 1f01a9b21f1cf1a622fd10f3af40ec9d 189 Pfam PF03352 Methyladenine glycosylase 15 181 9.1E-64 T 14-10-2018 IPR005019 Methyladenine glycosylase GO:0006284|GO:0008725 MB46_18215 66ff40445a209452c78e44173d740646 368 Gene3D G3DSA:3.40.50.720 1 128 1.9E-26 T 14-10-2018 MB46_18215 66ff40445a209452c78e44173d740646 368 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 8 121 2.3E-13 T 14-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 MB46_18215 66ff40445a209452c78e44173d740646 368 SUPERFAMILY SSF55347 133 295 9.32E-29 T 14-10-2018 MB46_18215 66ff40445a209452c78e44173d740646 368 SUPERFAMILY SSF51735 5 151 2.56E-35 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_18215 66ff40445a209452c78e44173d740646 368 Gene3D G3DSA:3.30.360.10 132 347 3.3E-34 T 14-10-2018 MB46_16365 1518cbe7204a4556782ed223227f2599 471 Gene3D G3DSA:3.40.190.10 180 419 1.3E-44 T 14-10-2018 MB46_16365 1518cbe7204a4556782ed223227f2599 471 Pfam PF01547 Bacterial extracellular solute-binding protein 79 375 1.2E-29 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein MB46_16365 1518cbe7204a4556782ed223227f2599 471 Gene3D G3DSA:3.40.190.10 92 417 1.3E-44 T 14-10-2018 MB46_16365 1518cbe7204a4556782ed223227f2599 471 SUPERFAMILY SSF53850 31 463 3.21E-39 T 14-10-2018 MB46_16365 1518cbe7204a4556782ed223227f2599 471 TIGRFAM TIGR03851 chitin_NgcE: carbohydrate ABC transporter, N-acetylglucosamine/diacetylchitobiose-binding protein 26 468 1.2E-177 T 14-10-2018 IPR022386 Carbohydrate ABC transporter, N-acetylglucosamine/diacetylchitobiose-binding protein MB46_12465 f7f002c2f3d2d25900e06d12f8c32a48 260 Gene3D G3DSA:1.10.10.1320 1 72 1.1E-15 T 14-10-2018 MB46_12465 f7f002c2f3d2d25900e06d12f8c32a48 260 Pfam PF10099 Anti-sigma-K factor rskA 58 258 5.8E-34 T 14-10-2018 IPR018764 Anti-sigma K factor RskA GO:0005886|GO:0016021 MB46_17345 c85fedceb19ba722762ee899478b43e1 263 SUPERFAMILY SSF46785 6 59 2.01E-10 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_17345 c85fedceb19ba722762ee899478b43e1 263 SMART SM00420 6 58 3.1E-14 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MB46_17345 c85fedceb19ba722762ee899478b43e1 263 Gene3D G3DSA:3.40.50.1360 73 232 8.2E-6 T 14-10-2018 MB46_17345 c85fedceb19ba722762ee899478b43e1 263 Pfam PF08220 DeoR-like helix-turn-helix domain 6 58 2.4E-14 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MB46_17345 c85fedceb19ba722762ee899478b43e1 263 Pfam PF00455 DeoR C terminal sensor domain 77 233 2.3E-49 T 14-10-2018 IPR014036 DeoR C-terminal sensor domain MB46_17345 c85fedceb19ba722762ee899478b43e1 263 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 14-10-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 MB46_17345 c85fedceb19ba722762ee899478b43e1 263 SUPERFAMILY SSF100950 77 235 8.37E-35 T 14-10-2018 IPR037171 NagB/RpiA transferase-like MB46_17345 c85fedceb19ba722762ee899478b43e1 263 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 1.2E-8 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MB46_17345 c85fedceb19ba722762ee899478b43e1 263 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 1.2E-8 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MB46_17345 c85fedceb19ba722762ee899478b43e1 263 SMART SM01134 74 235 8.9E-61 T 14-10-2018 MB46_17345 c85fedceb19ba722762ee899478b43e1 263 Gene3D G3DSA:1.10.10.10 8 58 6.3E-6 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_11550 722d55db75c929a8209c0ccfe340f566 668 Pfam PF13641 Glycosyltransferase like family 2 195 449 9.2E-41 T 14-10-2018 MB46_11550 722d55db75c929a8209c0ccfe340f566 668 Gene3D G3DSA:3.90.550.60 16 433 8.0E-130 T 14-10-2018 MB46_11550 722d55db75c929a8209c0ccfe340f566 668 SUPERFAMILY SSF53448 202 450 1.24E-27 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MB46_03570 c5107a542cde24f913d92e082e0435e0 336 Gene3D G3DSA:3.40.50.920 202 323 5.0E-41 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 MB46_03570 c5107a542cde24f913d92e082e0435e0 336 SMART SM00861 4 179 4.5E-65 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain MB46_03570 c5107a542cde24f913d92e082e0435e0 336 SUPERFAMILY SSF52922 195 325 1.83E-33 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 MB46_03570 c5107a542cde24f913d92e082e0435e0 336 SUPERFAMILY SSF52518 3 183 2.55E-66 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold MB46_03570 c5107a542cde24f913d92e082e0435e0 336 Gene3D G3DSA:3.40.50.970 1 201 1.3E-76 T 14-10-2018 MB46_03570 c5107a542cde24f913d92e082e0435e0 336 Pfam PF02780 Transketolase, C-terminal domain 196 316 3.8E-35 T 14-10-2018 IPR033248 Transketolase, C-terminal domain MB46_03570 c5107a542cde24f913d92e082e0435e0 336 Pfam PF02779 Transketolase, pyrimidine binding domain 3 178 1.8E-43 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain MB46_10805 692ce19373617c0706d015fe07c3f78e 231 Gene3D G3DSA:2.70.180.20 1 99 2.0E-17 T 14-10-2018 MB46_10805 692ce19373617c0706d015fe07c3f78e 231 Pfam PF01939 Endonuclease NucS 1 230 1.1E-76 T 14-10-2018 IPR002793 Endonuclease NucS GO:0004519 MB46_10805 692ce19373617c0706d015fe07c3f78e 231 Gene3D G3DSA:3.40.1350.10 106 217 2.4E-28 T 14-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 MB46_10805 692ce19373617c0706d015fe07c3f78e 231 Hamap MF_00722 Endonuclease NucS [nucS]. 1 223 32.332 T 14-10-2018 IPR002793 Endonuclease NucS GO:0004519 MB46_12720 bc54b242e4917ca2b61b7331a9ff59b8 331 Pfam PF01544 CorA-like Mg2+ transporter protein 33 327 1.0E-65 T 14-10-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 MB46_12720 bc54b242e4917ca2b61b7331a9ff59b8 331 SUPERFAMILY SSF143865 6 249 3.01E-64 T 14-10-2018 MB46_12720 bc54b242e4917ca2b61b7331a9ff59b8 331 TIGRFAM TIGR00383 corA: magnesium and cobalt transport protein CorA 34 331 1.9E-66 T 14-10-2018 IPR004488 Magnesium/cobalt transport protein CorA GO:0006824|GO:0015087|GO:0015095|GO:0015693|GO:0016020 MB46_12720 bc54b242e4917ca2b61b7331a9ff59b8 331 Gene3D G3DSA:1.20.58.340 255 331 1.7E-24 T 14-10-2018 MB46_12720 bc54b242e4917ca2b61b7331a9ff59b8 331 Gene3D G3DSA:3.30.460.20 10 133 4.3E-27 T 14-10-2018 MB46_12720 bc54b242e4917ca2b61b7331a9ff59b8 331 Gene3D G3DSA:1.20.58.340 134 245 3.2E-30 T 14-10-2018 MB46_12720 bc54b242e4917ca2b61b7331a9ff59b8 331 SUPERFAMILY SSF144083 268 328 3.4E-19 T 14-10-2018 MB46_01395 b233f085d767db749be60cf109e5a0b0 485 Gene3D G3DSA:3.30.420.40 1 261 9.4E-83 T 14-10-2018 MB46_01395 b233f085d767db749be60cf109e5a0b0 485 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 4 260 7.5E-40 T 14-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 MB46_01395 b233f085d767db749be60cf109e5a0b0 485 SUPERFAMILY SSF53067 4 262 2.59E-45 T 14-10-2018 MB46_01395 b233f085d767db749be60cf109e5a0b0 485 TIGRFAM TIGR01312 XylB: xylulokinase 6 454 6.0E-115 T 14-10-2018 IPR006000 Xylulokinase GO:0004856|GO:0005997 KEGG: 00040+2.7.1.17 MB46_01395 b233f085d767db749be60cf109e5a0b0 485 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 269 451 8.7E-26 T 14-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 MB46_01395 b233f085d767db749be60cf109e5a0b0 485 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 122 134 - T 14-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 MB46_01395 b233f085d767db749be60cf109e5a0b0 485 Gene3D G3DSA:3.30.420.40 262 484 5.4E-65 T 14-10-2018 MB46_01395 b233f085d767db749be60cf109e5a0b0 485 SUPERFAMILY SSF53067 265 479 2.59E-43 T 14-10-2018 MB46_01395 b233f085d767db749be60cf109e5a0b0 485 PIRSF PIRSF000538 1 467 1.1E-78 T 14-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 MB46_12330 f4db3753586e00d9b425022e0b391d46 234 Gene3D G3DSA:1.20.1260.10 12 234 1.3E-77 T 14-10-2018 IPR012347 Ferritin-like MB46_12330 f4db3753586e00d9b425022e0b391d46 234 SUPERFAMILY SSF47240 26 148 1.83E-7 T 14-10-2018 IPR009078 Ferritin-like superfamily MB46_12330 f4db3753586e00d9b425022e0b391d46 234 Pfam PF13794 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like 19 197 8.3E-74 T 14-10-2018 MB46_15845 3b9ee93fbec3b3e12d1a3918fe813f7e 363 Pfam PF00356 Bacterial regulatory proteins, lacI family 34 78 2.9E-16 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MB46_15845 3b9ee93fbec3b3e12d1a3918fe813f7e 363 Gene3D G3DSA:3.40.50.2300 189 350 5.4E-70 T 14-10-2018 MB46_15845 3b9ee93fbec3b3e12d1a3918fe813f7e 363 SUPERFAMILY SSF47413 32 87 9.55E-16 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MB46_15845 3b9ee93fbec3b3e12d1a3918fe813f7e 363 Gene3D G3DSA:1.10.260.40 23 88 2.3E-22 T 14-10-2018 MB46_15845 3b9ee93fbec3b3e12d1a3918fe813f7e 363 Pfam PF13377 Periplasmic binding protein-like domain 198 355 1.1E-34 T 14-10-2018 MB46_15845 3b9ee93fbec3b3e12d1a3918fe813f7e 363 SMART SM00354 31 101 1.5E-24 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MB46_15845 3b9ee93fbec3b3e12d1a3918fe813f7e 363 Gene3D G3DSA:3.40.50.2300 107 346 5.4E-70 T 14-10-2018 MB46_15845 3b9ee93fbec3b3e12d1a3918fe813f7e 363 SUPERFAMILY SSF53822 91 349 1.99E-60 T 14-10-2018 IPR028082 Periplasmic binding protein-like I MB46_08660 c5056ed2fa238cd4831167f8bb8eb595 124 Pfam PF02699 Preprotein translocase subunit 3 79 7.3E-18 T 14-10-2018 IPR003849 Preprotein translocase YajC MB46_08660 c5056ed2fa238cd4831167f8bb8eb595 124 SMART SM01323 1 81 1.3E-18 T 14-10-2018 IPR003849 Preprotein translocase YajC MB46_08660 c5056ed2fa238cd4831167f8bb8eb595 124 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 3 81 2.0E-15 T 14-10-2018 IPR003849 Preprotein translocase YajC MB46_10220 d6f3db1b183bf48bfef424fc4a00f067 170 SUPERFAMILY SSF55021 2 75 5.46E-22 T 14-10-2018 MB46_10220 d6f3db1b183bf48bfef424fc4a00f067 170 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 3 77 2.0E-33 T 14-10-2018 MB46_10220 d6f3db1b183bf48bfef424fc4a00f067 170 Gene3D G3DSA:3.30.70.1150 84 163 1.4E-25 T 14-10-2018 IPR027271 Acetolactate synthase/Transcription factor NikR, C-terminal MB46_10220 d6f3db1b183bf48bfef424fc4a00f067 170 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 3 158 5.1E-56 T 14-10-2018 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 MB46_10220 d6f3db1b183bf48bfef424fc4a00f067 170 Pfam PF13710 ACT domain 12 74 7.6E-16 T 14-10-2018 MB46_10220 d6f3db1b183bf48bfef424fc4a00f067 170 SUPERFAMILY SSF55021 80 162 3.02E-24 T 14-10-2018 MB46_10220 d6f3db1b183bf48bfef424fc4a00f067 170 Gene3D G3DSA:3.30.70.260 1 80 7.6E-34 T 14-10-2018 MB46_10220 d6f3db1b183bf48bfef424fc4a00f067 170 Pfam PF10369 Small subunit of acetolactate synthase 85 158 4.2E-24 T 14-10-2018 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 MB46_15660 c1a33133afab4f818272ee3a7e4188e0 324 Pfam PF01758 Sodium Bile acid symporter family 56 233 5.6E-40 T 14-10-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 MB46_15660 c1a33133afab4f818272ee3a7e4188e0 324 Gene3D G3DSA:1.20.1530.20 23 324 5.8E-97 T 14-10-2018 IPR038770 Sodium/solute symporter superfamily MB46_04385 7f21eff7bcf233534410fdfdca18432b 632 Pfam PF13193 AMP-binding enzyme C-terminal domain 517 595 5.4E-23 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain MB46_04385 7f21eff7bcf233534410fdfdca18432b 632 Gene3D G3DSA:3.40.50.12780 35 500 5.6E-107 T 14-10-2018 MB46_04385 7f21eff7bcf233534410fdfdca18432b 632 SUPERFAMILY SSF56801 8 629 1.44E-156 T 14-10-2018 MB46_04385 7f21eff7bcf233534410fdfdca18432b 632 ProSitePatterns PS00455 Putative AMP-binding domain signature. 243 254 - T 14-10-2018 IPR020845 AMP-binding, conserved site MB46_04385 7f21eff7bcf233534410fdfdca18432b 632 Pfam PF00501 AMP-binding enzyme 66 507 7.5E-83 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 MB46_04385 7f21eff7bcf233534410fdfdca18432b 632 Gene3D G3DSA:3.30.300.30 503 629 1.1E-22 T 14-10-2018 MB46_04385 7f21eff7bcf233534410fdfdca18432b 632 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 8 62 1.9E-17 T 14-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 MB46_19085 ea30f4b3c0a5bae74ce8334ec4362d59 332 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 81 328 6.0E-58 T 14-10-2018 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 Reactome: R-HSA-6793080 MB46_19085 ea30f4b3c0a5bae74ce8334ec4362d59 332 Gene3D G3DSA:3.30.1330.30 71 154 5.2E-9 T 14-10-2018 IPR029064 50S ribosomal protein L30e-like MB46_19085 ea30f4b3c0a5bae74ce8334ec4362d59 332 SUPERFAMILY SSF55315 77 155 1.02E-15 T 14-10-2018 IPR029064 50S ribosomal protein L30e-like MB46_19085 ea30f4b3c0a5bae74ce8334ec4362d59 332 Gene3D G3DSA:3.40.1280.10 165 329 2.3E-47 T 14-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal MB46_19085 ea30f4b3c0a5bae74ce8334ec4362d59 332 SUPERFAMILY SSF75217 147 329 2.29E-41 T 14-10-2018 IPR029028 Alpha/beta knot methyltransferases MB46_19085 ea30f4b3c0a5bae74ce8334ec4362d59 332 Pfam PF00588 SpoU rRNA Methylase family 181 322 5.9E-33 T 14-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 MB46_19085 ea30f4b3c0a5bae74ce8334ec4362d59 332 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 82 157 6.7E-17 T 14-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 MB46_19085 ea30f4b3c0a5bae74ce8334ec4362d59 332 SMART SM00967 82 158 6.1E-16 T 14-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 MB46_04160 92b88fd06f099d3bcf9bbc0ea812fb38 178 Hamap MF_00173 Arginine repressor [argR]. 1 174 51.862 T 14-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 MB46_04160 92b88fd06f099d3bcf9bbc0ea812fb38 178 SUPERFAMILY SSF46785 12 81 9.07E-16 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_04160 92b88fd06f099d3bcf9bbc0ea812fb38 178 SUPERFAMILY SSF55252 103 170 3.14E-17 T 14-10-2018 IPR036251 Arginine repressor, C-terminal domain superfamily GO:0034618|GO:0051259 MB46_04160 92b88fd06f099d3bcf9bbc0ea812fb38 178 PRINTS PR01467 Bacterial arginine repressor signature 33 46 2.2E-23 T 14-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 MB46_04160 92b88fd06f099d3bcf9bbc0ea812fb38 178 PRINTS PR01467 Bacterial arginine repressor signature 110 123 2.2E-23 T 14-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 MB46_04160 92b88fd06f099d3bcf9bbc0ea812fb38 178 PRINTS PR01467 Bacterial arginine repressor signature 140 155 2.2E-23 T 14-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 MB46_04160 92b88fd06f099d3bcf9bbc0ea812fb38 178 PRINTS PR01467 Bacterial arginine repressor signature 49 64 2.2E-23 T 14-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 MB46_04160 92b88fd06f099d3bcf9bbc0ea812fb38 178 Pfam PF01316 Arginine repressor, DNA binding domain 14 81 6.7E-21 T 14-10-2018 IPR020900 Arginine repressor, DNA-binding domain GO:0003700|GO:0006355|GO:0006525 MB46_04160 92b88fd06f099d3bcf9bbc0ea812fb38 178 Gene3D G3DSA:1.10.10.10 1 84 1.8E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_04160 92b88fd06f099d3bcf9bbc0ea812fb38 178 ProDom PD007402 ARGININE REPRESSOR TRANSCRIPTION BIOSYNTHESIS DNA-BINDING REGULATION AMINO-ACID ARGR TRANSCRIPTIONAL FAMILY 112 167 2.0E-14 T 14-10-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 MB46_04160 92b88fd06f099d3bcf9bbc0ea812fb38 178 Gene3D G3DSA:3.30.1360.40 94 170 1.6E-27 T 14-10-2018 MB46_04160 92b88fd06f099d3bcf9bbc0ea812fb38 178 TIGRFAM TIGR01529 argR_whole: arginine repressor 17 169 4.1E-39 T 14-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 MB46_04160 92b88fd06f099d3bcf9bbc0ea812fb38 178 Pfam PF02863 Arginine repressor, C-terminal domain 104 168 2.1E-22 T 14-10-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 MB46_00960 85246dc542541cba06bc1fb5304b31bc 596 Pfam PF13625 Helicase conserved C-terminal domain 372 454 1.9E-19 T 14-10-2018 IPR032830 Helicase XPB/Ssl2, N-terminal domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 MB46_05080 46cc1a2e5a125b9e9d559eabb1c65362 267 TIGRFAM TIGR01198 pgl: 6-phosphogluconolactonase 16 258 1.5E-62 T 14-10-2018 IPR005900 6-phosphogluconolactonase, DevB-type GO:0005975|GO:0006098|GO:0017057 KEGG: 00030+3.1.1.31 MB46_05080 46cc1a2e5a125b9e9d559eabb1c65362 267 Gene3D G3DSA:3.40.50.1360 1 258 2.1E-77 T 14-10-2018 MB46_05080 46cc1a2e5a125b9e9d559eabb1c65362 267 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 14 248 2.4E-68 T 14-10-2018 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 MB46_05080 46cc1a2e5a125b9e9d559eabb1c65362 267 SUPERFAMILY SSF100950 6 259 2.51E-60 T 14-10-2018 IPR037171 NagB/RpiA transferase-like MB46_09035 e0e2852363c946d0256a978c4c295fcd 381 Gene3D G3DSA:3.40.50.2000 5 178 2.7E-61 T 14-10-2018 MB46_09035 e0e2852363c946d0256a978c4c295fcd 381 SUPERFAMILY SSF53756 3 369 5.8E-74 T 14-10-2018 MB46_09035 e0e2852363c946d0256a978c4c295fcd 381 Pfam PF00534 Glycosyl transferases group 1 191 343 9.4E-27 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 MB46_09035 e0e2852363c946d0256a978c4c295fcd 381 Gene3D G3DSA:3.40.50.2000 179 349 2.7E-61 T 14-10-2018 MB46_09035 e0e2852363c946d0256a978c4c295fcd 381 Pfam PF13439 Glycosyltransferase Family 4 15 182 1.7E-22 T 14-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 MB46_18710 b734d1d3754d03f132521bfbdad95616 143 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 1 143 46.53 T 14-10-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 MB46_18710 b734d1d3754d03f132521bfbdad95616 143 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 47 84 - T 14-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 MB46_18710 b734d1d3754d03f132521bfbdad95616 143 Pfam PF14437 MafB19-like deaminase 4 140 3.3E-34 T 14-10-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 MB46_18710 b734d1d3754d03f132521bfbdad95616 143 SUPERFAMILY SSF53927 1 142 6.36E-52 T 14-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 MB46_18710 b734d1d3754d03f132521bfbdad95616 143 Gene3D G3DSA:3.40.140.10 1 143 8.4E-56 T 14-10-2018 MB46_07535 605065f3f2b3ab55b35b67708311b9e2 607 SUPERFAMILY SSF116726 224 294 7.59E-5 T 14-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 MB46_07535 605065f3f2b3ab55b35b67708311b9e2 607 Pfam PF03600 Citrate transporter 16 201 1.3E-30 T 14-10-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 MB46_07535 605065f3f2b3ab55b35b67708311b9e2 607 Pfam PF03600 Citrate transporter 426 599 2.3E-20 T 14-10-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 MB46_07535 605065f3f2b3ab55b35b67708311b9e2 607 SUPERFAMILY SSF116726 316 398 1.7E-5 T 14-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 MB46_14360 daaaf6e317f6e8650c38fd4d206aaa02 432 Pfam PF02817 e3 binding domain 136 169 1.3E-10 T 14-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 MB46_14360 daaaf6e317f6e8650c38fd4d206aaa02 432 Gene3D G3DSA:4.10.320.10 124 174 4.5E-12 T 14-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 MB46_14360 daaaf6e317f6e8650c38fd4d206aaa02 432 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 36 65 - T 14-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 MB46_14360 daaaf6e317f6e8650c38fd4d206aaa02 432 SUPERFAMILY SSF52777 204 430 1.11E-66 T 14-10-2018 MB46_14360 daaaf6e317f6e8650c38fd4d206aaa02 432 SUPERFAMILY SSF47005 131 171 3.27E-9 T 14-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 MB46_14360 daaaf6e317f6e8650c38fd4d206aaa02 432 Pfam PF00364 Biotin-requiring enzyme 14 85 1.0E-18 T 14-10-2018 IPR000089 Biotin/lipoyl attachment MB46_14360 daaaf6e317f6e8650c38fd4d206aaa02 432 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 205 429 1.5E-64 T 14-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 MB46_14360 daaaf6e317f6e8650c38fd4d206aaa02 432 Gene3D G3DSA:3.30.559.10 210 429 1.0E-70 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 MB46_14360 daaaf6e317f6e8650c38fd4d206aaa02 432 Gene3D G3DSA:2.40.50.100 13 89 3.2E-21 T 14-10-2018 MB46_14360 daaaf6e317f6e8650c38fd4d206aaa02 432 SUPERFAMILY SSF51230 13 97 6.15E-24 T 14-10-2018 IPR011053 Single hybrid motif MB46_15595 a64fdd457c99b2118b2b2c793b66a12c 108 Pfam PF00581 Rhodanese-like domain 14 92 2.7E-14 T 14-10-2018 IPR001763 Rhodanese-like domain MB46_15595 a64fdd457c99b2118b2b2c793b66a12c 108 Gene3D G3DSA:3.40.250.10 8 107 2.3E-27 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily MB46_15595 a64fdd457c99b2118b2b2c793b66a12c 108 SUPERFAMILY SSF52821 3 100 6.94E-32 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily MB46_15595 a64fdd457c99b2118b2b2c793b66a12c 108 SMART SM00450 2 96 2.8E-23 T 14-10-2018 IPR001763 Rhodanese-like domain MB46_08960 02bc9e5db9cc537ddb76f1bf4135aff2 85 Gene3D G3DSA:2.40.50.100 21 85 6.9E-27 T 14-10-2018 MB46_08960 02bc9e5db9cc537ddb76f1bf4135aff2 85 TIGRFAM TIGR00062 L27: ribosomal protein bL27 1 81 2.8E-34 T 14-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_08960 02bc9e5db9cc537ddb76f1bf4135aff2 85 Pfam PF01016 Ribosomal L27 protein 2 80 8.6E-36 T 14-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_08960 02bc9e5db9cc537ddb76f1bf4135aff2 85 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 1 83 27.065 T 14-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_08960 02bc9e5db9cc537ddb76f1bf4135aff2 85 ProSitePatterns PS00831 Ribosomal protein L27 signature. 34 48 - T 14-10-2018 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MB46_08960 02bc9e5db9cc537ddb76f1bf4135aff2 85 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 28 72 1.0E-16 T 14-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_08960 02bc9e5db9cc537ddb76f1bf4135aff2 85 SUPERFAMILY SSF110324 2 81 5.23E-31 T 14-10-2018 MB46_08960 02bc9e5db9cc537ddb76f1bf4135aff2 85 PRINTS PR00063 Ribosomal protein L27 signature 4 28 6.0E-36 T 14-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_08960 02bc9e5db9cc537ddb76f1bf4135aff2 85 PRINTS PR00063 Ribosomal protein L27 signature 54 78 6.0E-36 T 14-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_08960 02bc9e5db9cc537ddb76f1bf4135aff2 85 PRINTS PR00063 Ribosomal protein L27 signature 29 53 6.0E-36 T 14-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_14085 169960d26737d6c1209855e0622f8d33 155 Pfam PF01475 Ferric uptake regulator family 15 127 1.7E-17 T 14-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 MB46_14085 169960d26737d6c1209855e0622f8d33 155 SUPERFAMILY SSF46785 6 136 2.57E-31 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_14085 169960d26737d6c1209855e0622f8d33 155 Gene3D G3DSA:1.10.10.10 5 84 3.6E-12 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_14085 169960d26737d6c1209855e0622f8d33 155 Gene3D G3DSA:3.30.1490.190 86 149 6.2E-14 T 14-10-2018 MB46_09565 cf69e7884365cd3112a1c409a208c45b 119 SUPERFAMILY SSF50104 1 115 3.31E-45 T 14-10-2018 IPR008991 Translation protein SH3-like domain superfamily MB46_09565 cf69e7884365cd3112a1c409a208c45b 119 Pfam PF01245 Ribosomal protein L19 3 112 2.5E-47 T 14-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_09565 cf69e7884365cd3112a1c409a208c45b 119 Gene3D G3DSA:2.30.30.790 10 114 1.2E-14 T 14-10-2018 IPR038657 Ribosomal protein L19 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_09565 cf69e7884365cd3112a1c409a208c45b 119 ProSitePatterns PS01015 Ribosomal protein L19 signature. 85 100 - T 14-10-2018 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MB46_09565 cf69e7884365cd3112a1c409a208c45b 119 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 1 113 29.065 T 14-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_09565 cf69e7884365cd3112a1c409a208c45b 119 PRINTS PR00061 Ribosomal protein L19 signature 3 32 2.6E-41 T 14-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_09565 cf69e7884365cd3112a1c409a208c45b 119 PRINTS PR00061 Ribosomal protein L19 signature 87 112 2.6E-41 T 14-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_09565 cf69e7884365cd3112a1c409a208c45b 119 PRINTS PR00061 Ribosomal protein L19 signature 33 62 2.6E-41 T 14-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_09565 cf69e7884365cd3112a1c409a208c45b 119 PIRSF PIRSF002191 1 119 4.8E-47 T 14-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_09565 cf69e7884365cd3112a1c409a208c45b 119 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 1 112 3.2E-47 T 14-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_07155 d27c945dce66dd57bbf504d5ee069bff 538 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 58 511 1.3E-57 T 14-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 MB46_07155 d27c945dce66dd57bbf504d5ee069bff 538 SUPERFAMILY SSF56601 49 516 4.96E-58 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like MB46_07155 d27c945dce66dd57bbf504d5ee069bff 538 Gene3D G3DSA:3.40.710.10 297 519 4.5E-38 T 14-10-2018 MB46_07155 d27c945dce66dd57bbf504d5ee069bff 538 TIGRFAM TIGR00666 PBP4: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase 78 510 5.6E-47 T 14-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 MB46_07155 d27c945dce66dd57bbf504d5ee069bff 538 Gene3D G3DSA:3.50.80.20 116 226 4.1E-9 T 14-10-2018 MB46_05510 03a7ca44c32629a224e4fd5c2656f894 243 Gene3D G3DSA:3.90.1200.10 78 243 2.2E-11 T 14-10-2018 MB46_05510 03a7ca44c32629a224e4fd5c2656f894 243 SUPERFAMILY SSF56112 5 196 9.18E-25 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily MB46_05510 03a7ca44c32629a224e4fd5c2656f894 243 Pfam PF01636 Phosphotransferase enzyme family 104 159 5.6E-13 T 14-10-2018 IPR002575 Aminoglycoside phosphotransferase MB46_02805 697a9847ec9e63f76b575114a64d5980 205 TIGRFAM TIGR00172 maf: septum formation protein Maf 1 191 2.9E-46 T 14-10-2018 IPR003697 Maf-like protein GO:0047429 MB46_02805 697a9847ec9e63f76b575114a64d5980 205 SUPERFAMILY SSF52972 2 191 1.96E-49 T 14-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like MB46_02805 697a9847ec9e63f76b575114a64d5980 205 Pfam PF02545 Maf-like protein 5 192 1.0E-44 T 14-10-2018 IPR003697 Maf-like protein GO:0047429 MB46_02805 697a9847ec9e63f76b575114a64d5980 205 Hamap MF_00528 Septum formation protein Maf [maf]. 4 198 26.726 T 14-10-2018 IPR003697 Maf-like protein GO:0047429 MB46_02805 697a9847ec9e63f76b575114a64d5980 205 PIRSF PIRSF006305 1 199 5.6E-40 T 14-10-2018 IPR003697 Maf-like protein GO:0047429 MB46_02805 697a9847ec9e63f76b575114a64d5980 205 Gene3D G3DSA:3.90.950.10 4 199 8.8E-60 T 14-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like MB46_13770 ea4cc5102ccfbbabfa5e0c87abacb079 348 SUPERFAMILY SSF53850 61 291 5.29E-30 T 14-10-2018 MB46_13770 ea4cc5102ccfbbabfa5e0c87abacb079 348 Pfam PF09084 NMT1/THI5 like 76 261 1.9E-22 T 14-10-2018 IPR015168 SsuA/THI5-like MB46_13770 ea4cc5102ccfbbabfa5e0c87abacb079 348 Gene3D G3DSA:3.40.190.10 40 330 1.2E-37 T 14-10-2018 MB46_13770 ea4cc5102ccfbbabfa5e0c87abacb079 348 Gene3D G3DSA:3.40.190.10 117 223 1.2E-37 T 14-10-2018 MB46_15880 674e1fdfd9270d87a9350691058314e9 427 Pfam PF02127 Aminopeptidase I zinc metalloprotease (M18) 13 423 4.4E-121 T 14-10-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 MB46_15880 674e1fdfd9270d87a9350691058314e9 427 Gene3D G3DSA:3.40.630.10 10 422 7.2E-144 T 14-10-2018 MB46_15880 674e1fdfd9270d87a9350691058314e9 427 SUPERFAMILY SSF101821 86 202 1.1E-27 T 14-10-2018 MB46_15880 674e1fdfd9270d87a9350691058314e9 427 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 74 90 2.3E-35 T 14-10-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 MB46_15880 674e1fdfd9270d87a9350691058314e9 427 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 258 276 2.3E-35 T 14-10-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 MB46_15880 674e1fdfd9270d87a9350691058314e9 427 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 107 127 2.3E-35 T 14-10-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 MB46_15880 674e1fdfd9270d87a9350691058314e9 427 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 390 405 2.3E-35 T 14-10-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 MB46_15880 674e1fdfd9270d87a9350691058314e9 427 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 301 317 2.3E-35 T 14-10-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 MB46_15880 674e1fdfd9270d87a9350691058314e9 427 Gene3D G3DSA:2.30.250.10 84 207 7.2E-144 T 14-10-2018 IPR023358 Peptidase M18, domain 2 GO:0004177 MB46_15880 674e1fdfd9270d87a9350691058314e9 427 SUPERFAMILY SSF53187 5 424 1.2E-93 T 14-10-2018 MB46_02055 1f8c50891b667960fed42ff9f62cd09e 372 PIRSF PIRSF000808 36 366 3.6E-102 T 14-10-2018 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0008108|GO:0008270|GO:0033499 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 MB46_02055 1f8c50891b667960fed42ff9f62cd09e 372 ProSitePatterns PS00117 Galactose-1-phosphate uridyl transferase family 1 active site signature. 174 191 - T 14-10-2018 IPR019779 Galactose-1-phosphate uridyl transferase, class I His-active site KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 MB46_02055 1f8c50891b667960fed42ff9f62cd09e 372 Gene3D G3DSA:3.30.428.10 45 361 4.3E-92 T 14-10-2018 IPR036265 HIT-like superfamily MB46_02055 1f8c50891b667960fed42ff9f62cd09e 372 Pfam PF02744 Galactose-1-phosphate uridyl transferase, C-terminal domain 211 365 9.0E-18 T 14-10-2018 IPR005850 Galactose-1-phosphate uridyl transferase, C-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 MB46_02055 1f8c50891b667960fed42ff9f62cd09e 372 SUPERFAMILY SSF54197 42 200 1.55E-47 T 14-10-2018 IPR036265 HIT-like superfamily MB46_02055 1f8c50891b667960fed42ff9f62cd09e 372 TIGRFAM TIGR00209 galT_1: galactose-1-phosphate uridylyltransferase 46 364 1.6E-42 T 14-10-2018 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0008108|GO:0008270|GO:0033499 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 MB46_02055 1f8c50891b667960fed42ff9f62cd09e 372 SUPERFAMILY SSF54197 204 364 2.89E-35 T 14-10-2018 IPR036265 HIT-like superfamily MB46_02055 1f8c50891b667960fed42ff9f62cd09e 372 Gene3D G3DSA:3.30.428.10 74 198 4.3E-92 T 14-10-2018 IPR036265 HIT-like superfamily MB46_02055 1f8c50891b667960fed42ff9f62cd09e 372 Pfam PF01087 Galactose-1-phosphate uridyl transferase, N-terminal domain 40 199 2.6E-35 T 14-10-2018 IPR005849 Galactose-1-phosphate uridyl transferase, N-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 MB46_18190 3bc7694c5e33789cc7c28d0da7cda048 557 Hamap MF_01491 Ribonuclease J [rnj]. 12 557 38.175 T 14-10-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 MB46_18190 3bc7694c5e33789cc7c28d0da7cda048 557 Gene3D G3DSA:3.10.20.580 458 557 2.2E-7 T 14-10-2018 MB46_18190 3bc7694c5e33789cc7c28d0da7cda048 557 Gene3D G3DSA:3.40.50.10710 215 372 6.7E-177 T 14-10-2018 MB46_18190 3bc7694c5e33789cc7c28d0da7cda048 557 PIRSF PIRSF004803 10 557 3.5E-193 T 14-10-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 MB46_18190 3bc7694c5e33789cc7c28d0da7cda048 557 SMART SM00849 29 223 8.7E-20 T 14-10-2018 IPR001279 Metallo-beta-lactamase MB46_18190 3bc7694c5e33789cc7c28d0da7cda048 557 Gene3D G3DSA:3.60.15.10 18 443 6.7E-177 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MB46_18190 3bc7694c5e33789cc7c28d0da7cda048 557 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 18 550 5.9E-141 T 14-10-2018 IPR004613 Ribonuclease J GO:0003723|GO:0046872 MB46_18190 3bc7694c5e33789cc7c28d0da7cda048 557 Pfam PF00753 Metallo-beta-lactamase superfamily 26 172 1.4E-12 T 14-10-2018 IPR001279 Metallo-beta-lactamase MB46_18190 3bc7694c5e33789cc7c28d0da7cda048 557 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 368 416 2.4E-9 T 14-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain MB46_18190 3bc7694c5e33789cc7c28d0da7cda048 557 SUPERFAMILY SSF56281 17 431 8.62E-91 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MB46_09900 dafe00ee84b59c9dc9e0e0200dbbe12d 379 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 267 273 - T 14-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 MB46_09900 dafe00ee84b59c9dc9e0e0200dbbe12d 379 Gene3D G3DSA:3.40.50.150 163 332 3.4E-24 T 14-10-2018 MB46_09900 dafe00ee84b59c9dc9e0e0200dbbe12d 379 Pfam PF05175 Methyltransferase small domain 200 316 1.2E-12 T 14-10-2018 IPR007848 Methyltransferase small domain GO:0008168 MB46_09900 dafe00ee84b59c9dc9e0e0200dbbe12d 379 SUPERFAMILY SSF53335 176 317 9.23E-27 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MB46_11570 9ad79a422708d7d2b4defb4194df8229 82 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 76 18.077 T 14-10-2018 IPR003482 Transcription factor WhiB MB46_11570 9ad79a422708d7d2b4defb4194df8229 82 Pfam PF02467 Transcription factor WhiB 3 71 3.1E-26 T 14-10-2018 IPR034768 WhiB-like iron-sulfur binding domain MB46_03875 8e00e77178d8106da96e25f9490ed9e3 301 SMART SM01130 10 298 1.8E-113 T 14-10-2018 IPR002220 DapA-like GO:0016829 MB46_03875 8e00e77178d8106da96e25f9490ed9e3 301 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 142 172 - T 14-10-2018 IPR020625 Schiff base-forming aldolase, active site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 MB46_03875 8e00e77178d8106da96e25f9490ed9e3 301 PIRSF PIRSF001365 8 301 4.6E-81 T 14-10-2018 IPR002220 DapA-like GO:0016829 MB46_03875 8e00e77178d8106da96e25f9490ed9e3 301 SUPERFAMILY SSF51569 10 298 3.56E-89 T 14-10-2018 MB46_03875 8e00e77178d8106da96e25f9490ed9e3 301 Gene3D G3DSA:3.20.20.70 2 300 4.3E-100 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MB46_03875 8e00e77178d8106da96e25f9490ed9e3 301 Pfam PF00701 Dihydrodipicolinate synthetase family 11 294 4.6E-78 T 14-10-2018 IPR002220 DapA-like GO:0016829 MB46_03875 8e00e77178d8106da96e25f9490ed9e3 301 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 14 292 3.4E-86 T 14-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MB46_03875 8e00e77178d8106da96e25f9490ed9e3 301 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 10 296 54.051 T 14-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MB46_03875 8e00e77178d8106da96e25f9490ed9e3 301 PRINTS PR00146 Dihydrodipicolinate synthase signature 137 154 2.8E-31 T 14-10-2018 IPR002220 DapA-like GO:0016829 MB46_03875 8e00e77178d8106da96e25f9490ed9e3 301 PRINTS PR00146 Dihydrodipicolinate synthase signature 44 65 2.8E-31 T 14-10-2018 IPR002220 DapA-like GO:0016829 MB46_03875 8e00e77178d8106da96e25f9490ed9e3 301 PRINTS PR00146 Dihydrodipicolinate synthase signature 80 98 2.8E-31 T 14-10-2018 IPR002220 DapA-like GO:0016829 MB46_03875 8e00e77178d8106da96e25f9490ed9e3 301 PRINTS PR00146 Dihydrodipicolinate synthase signature 112 128 2.8E-31 T 14-10-2018 IPR002220 DapA-like GO:0016829 MB46_05200 6d796618a9be9405e6bb8bd653b7fef9 297 Pfam PF02104 SURF1 family 21 225 2.3E-28 T 14-10-2018 IPR002994 Surfeit locus 1/Shy1 GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MB46_11435 519aaed6e2be6f1931b3bb0b2b6e9458 295 SUPERFAMILY SSF53448 2 239 6.65E-30 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MB46_11435 519aaed6e2be6f1931b3bb0b2b6e9458 295 Gene3D G3DSA:3.90.550.10 3 260 1.7E-27 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MB46_11435 519aaed6e2be6f1931b3bb0b2b6e9458 295 Pfam PF00535 Glycosyl transferase family 2 4 126 2.4E-14 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MB46_14805 d400ea9fad9c73d872cf99630bdd9fac 468 SUPERFAMILY SSF53223 86 235 1.01E-53 T 14-10-2018 MB46_14805 d400ea9fad9c73d872cf99630bdd9fac 468 SMART SM01274 92 225 1.2E-77 T 14-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 MB46_14805 d400ea9fad9c73d872cf99630bdd9fac 468 Pfam PF00390 Malic enzyme, N-terminal domain 93 225 2.8E-26 T 14-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 MB46_14805 d400ea9fad9c73d872cf99630bdd9fac 468 Gene3D G3DSA:3.40.50.720 235 468 5.0E-70 T 14-10-2018 MB46_14805 d400ea9fad9c73d872cf99630bdd9fac 468 Pfam PF03949 Malic enzyme, NAD binding domain 239 458 1.3E-20 T 14-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 MB46_14805 d400ea9fad9c73d872cf99630bdd9fac 468 PRINTS PR00072 Malic enzyme signature 154 176 3.4E-7 T 14-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 MB46_14805 d400ea9fad9c73d872cf99630bdd9fac 468 PRINTS PR00072 Malic enzyme signature 233 249 3.4E-7 T 14-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 MB46_14805 d400ea9fad9c73d872cf99630bdd9fac 468 PRINTS PR00072 Malic enzyme signature 264 280 3.4E-7 T 14-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 MB46_14805 d400ea9fad9c73d872cf99630bdd9fac 468 SUPERFAMILY SSF51735 237 463 2.32E-67 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_14805 d400ea9fad9c73d872cf99630bdd9fac 468 Gene3D G3DSA:3.40.50.10380 74 234 5.7E-68 T 14-10-2018 IPR037062 Malic enzyme, N-terminal domain superfamily GO:0004471|GO:0055114 MB46_14805 d400ea9fad9c73d872cf99630bdd9fac 468 PIRSF PIRSF000106 18 468 3.9E-79 T 14-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 MB46_14805 d400ea9fad9c73d872cf99630bdd9fac 468 SMART SM00919 237 459 1.2E-105 T 14-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 MB46_02130 b44f3d86fe12b3ee910d90ff88a9e387 253 Gene3D G3DSA:3.40.1180.10 8 253 4.7E-83 T 14-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 MB46_02130 b44f3d86fe12b3ee910d90ff88a9e387 253 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 198 215 - T 14-10-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199|Reactome: R-HSA-4755609 MB46_02130 b44f3d86fe12b3ee910d90ff88a9e387 253 Pfam PF01255 Putative undecaprenyl diphosphate synthase 32 252 3.8E-68 T 14-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 MB46_02130 b44f3d86fe12b3ee910d90ff88a9e387 253 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 24 252 4.4E-64 T 14-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 MB46_02130 b44f3d86fe12b3ee910d90ff88a9e387 253 SUPERFAMILY SSF64005 19 247 1.96E-71 T 14-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 MB46_02130 b44f3d86fe12b3ee910d90ff88a9e387 253 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 24 253 34.763 T 14-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 MB46_06285 a44347335041a6bfd6a427c6a5dc6b54 448 SUPERFAMILY SSF50621 304 418 3.4E-9 T 14-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 MB46_06285 a44347335041a6bfd6a427c6a5dc6b54 448 SUPERFAMILY SSF51419 29 321 1.89E-39 T 14-10-2018 IPR029066 PLP-binding barrel MB46_06285 a44347335041a6bfd6a427c6a5dc6b54 448 Gene3D G3DSA:2.40.37.10 294 446 1.0E-13 T 14-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 MB46_06285 a44347335041a6bfd6a427c6a5dc6b54 448 Gene3D G3DSA:3.20.20.10 28 249 1.1E-46 T 14-10-2018 IPR029066 PLP-binding barrel MB46_06285 a44347335041a6bfd6a427c6a5dc6b54 448 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 39 233 9.3E-27 T 14-10-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 MB46_17380 7ce8864ba0d0d33c088f6bf5e474611c 270 Pfam PF10576 Iron-sulfur binding domain of endonuclease III 194 210 1.8E-6 T 14-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 MB46_17380 7ce8864ba0d0d33c088f6bf5e474611c 270 Hamap MF_00942 Endonuclease III [nth]. 7 216 37.47 T 14-10-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 MB46_17380 7ce8864ba0d0d33c088f6bf5e474611c 270 SUPERFAMILY SSF48150 10 216 2.51E-68 T 14-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 MB46_17380 7ce8864ba0d0d33c088f6bf5e474611c 270 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 41 175 8.9E-20 T 14-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 MB46_17380 7ce8864ba0d0d33c088f6bf5e474611c 270 ProSitePatterns PS01155 Endonuclease III family signature. 109 138 - T 14-10-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 MB46_17380 7ce8864ba0d0d33c088f6bf5e474611c 270 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 194 210 - T 14-10-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 MB46_17380 7ce8864ba0d0d33c088f6bf5e474611c 270 Pfam PF00633 Helix-hairpin-helix motif 106 133 7.5E-8 T 14-10-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 MB46_17380 7ce8864ba0d0d33c088f6bf5e474611c 270 Gene3D G3DSA:1.10.1670.10 22 210 3.7E-73 T 14-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 MB46_17380 7ce8864ba0d0d33c088f6bf5e474611c 270 SMART SM00525 193 213 3.2E-7 T 14-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 MB46_17380 7ce8864ba0d0d33c088f6bf5e474611c 270 Gene3D G3DSA:1.10.340.30 28 139 3.7E-73 T 14-10-2018 MB46_17380 7ce8864ba0d0d33c088f6bf5e474611c 270 SMART SM00478 45 192 3.0E-58 T 14-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 MB46_17380 7ce8864ba0d0d33c088f6bf5e474611c 270 TIGRFAM TIGR01083 nth: endonuclease III 11 201 1.5E-74 T 14-10-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 MB46_11470 6bc90396da8d71912d818e676eacfd8c 538 Gene3D G3DSA:3.40.50.620 162 292 7.2E-9 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MB46_11470 6bc90396da8d71912d818e676eacfd8c 538 SUPERFAMILY SSF52402 183 267 2.51E-11 T 14-10-2018 MB46_11470 6bc90396da8d71912d818e676eacfd8c 538 SUPERFAMILY SSF56235 47 150 4.32E-10 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MB46_11470 6bc90396da8d71912d818e676eacfd8c 538 Gene3D G3DSA:3.60.20.10 22 153 5.4E-7 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MB46_08345 62d2a5013797252d184b25e8839c6d38 321 Gene3D G3DSA:3.30.420.40 129 301 3.0E-99 T 14-10-2018 MB46_08345 62d2a5013797252d184b25e8839c6d38 321 Pfam PF00480 ROK family 11 318 5.8E-72 T 14-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 MB46_08345 62d2a5013797252d184b25e8839c6d38 321 Gene3D G3DSA:3.30.420.40 11 314 3.0E-99 T 14-10-2018 MB46_08345 62d2a5013797252d184b25e8839c6d38 321 ProSitePatterns PS01125 ROK family signature. 137 164 - T 14-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 MB46_08345 62d2a5013797252d184b25e8839c6d38 321 TIGRFAM TIGR00744 ROK_glcA_fam: ROK family protein (putative glucokinase) 11 319 6.7E-79 T 14-10-2018 IPR004654 Glucokinase ROK GO:0004340|GO:0005737|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 MB46_08345 62d2a5013797252d184b25e8839c6d38 321 SUPERFAMILY SSF53067 9 317 5.19E-63 T 14-10-2018 MB46_13245 dd66ffdc05c6b7d01e01bc284d0d1282 191 SUPERFAMILY SSF55166 30 168 3.14E-32 T 14-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 MB46_13245 dd66ffdc05c6b7d01e01bc284d0d1282 191 Gene3D G3DSA:3.30.1380.10 1 184 1.9E-59 T 14-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 MB46_13245 dd66ffdc05c6b7d01e01bc284d0d1282 191 Pfam PF02557 D-alanyl-D-alanine carboxypeptidase 34 163 3.5E-38 T 14-10-2018 IPR003709 Peptidase M15B GO:0006508|GO:0008233 MB46_13880 53e7456f39736d9fb5522c0c219cce96 387 SUPERFAMILY SSF53383 5 384 6.38E-116 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MB46_13880 53e7456f39736d9fb5522c0c219cce96 387 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 196 210 - T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 MB46_13880 53e7456f39736d9fb5522c0c219cce96 387 Gene3D G3DSA:3.40.640.10 1 254 4.3E-92 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MB46_13880 53e7456f39736d9fb5522c0c219cce96 387 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 7 383 2.0E-143 T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 MB46_13880 53e7456f39736d9fb5522c0c219cce96 387 Gene3D G3DSA:3.90.1150.10 255 386 3.4E-54 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MB46_13880 53e7456f39736d9fb5522c0c219cce96 387 PIRSF PIRSF001434 1 387 2.1E-142 T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 MB46_14695 86241ad0c86cdf59206d62c93311880b 631 Pfam PF00920 Dehydratase family 34 610 2.9E-208 T 14-10-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 MB46_14695 86241ad0c86cdf59206d62c93311880b 631 SUPERFAMILY SSF143975 4 425 6.02E-127 T 14-10-2018 IPR037237 IlvD/EDD, N-terminal domain KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 MB46_14695 86241ad0c86cdf59206d62c93311880b 631 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 18 613 1.2E-231 T 14-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 MB46_14695 86241ad0c86cdf59206d62c93311880b 631 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 514 525 - T 14-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 MB46_14695 86241ad0c86cdf59206d62c93311880b 631 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 122 132 - T 14-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 MB46_14695 86241ad0c86cdf59206d62c93311880b 631 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 4 613 43.783 T 14-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 MB46_14695 86241ad0c86cdf59206d62c93311880b 631 Gene3D G3DSA:3.50.30.80 426 576 1.0E-54 T 14-10-2018 MB46_14695 86241ad0c86cdf59206d62c93311880b 631 SUPERFAMILY SSF52016 426 613 1.26E-59 T 14-10-2018 MB46_05665 1b662f032aa382c3e7d5747fd5e41931 504 ProSitePatterns PS00523 Sulfatases signature 1. 57 69 - T 14-10-2018 IPR024607 Sulfatase, conserved site MB46_05665 1b662f032aa382c3e7d5747fd5e41931 504 Gene3D G3DSA:3.40.720.10 10 481 5.1E-116 T 14-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 MB46_05665 1b662f032aa382c3e7d5747fd5e41931 504 Pfam PF16347 Domain of unknown function (DUF4976) 381 468 4.9E-7 T 14-10-2018 IPR032506 Domain of unknown function DUF4976 Reactome: R-HSA-2024096|Reactome: R-HSA-2206307 MB46_05665 1b662f032aa382c3e7d5747fd5e41931 504 SUPERFAMILY SSF53649 9 467 2.91E-103 T 14-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 MB46_05665 1b662f032aa382c3e7d5747fd5e41931 504 Pfam PF00884 Sulfatase 11 376 1.1E-56 T 14-10-2018 IPR000917 Sulfatase, N-terminal GO:0008484 MB46_05035 c86545fc755150427c76e574b5950b54 662 Pfam PF12826 Helix-hairpin-helix motif 593 640 3.3E-7 T 14-10-2018 MB46_05035 c86545fc755150427c76e574b5950b54 662 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 393 573 7.5E-52 T 14-10-2018 IPR001162 UvrC family homology region MB46_05035 c86545fc755150427c76e574b5950b54 662 Hamap MF_00203 UvrABC system protein C [uvrC]. 4 638 28.77 T 14-10-2018 IPR004791 UvrABC system, subunit C GO:0006289|GO:0009380|GO:0009381 MB46_05035 c86545fc755150427c76e574b5950b54 662 SUPERFAMILY SSF82771 18 101 1.83E-22 T 14-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 MB46_05035 c86545fc755150427c76e574b5950b54 662 Gene3D G3DSA:3.40.1440.10 6 103 5.5E-29 T 14-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 MB46_05035 c86545fc755150427c76e574b5950b54 662 SUPERFAMILY SSF47781 544 640 1.08E-23 T 14-10-2018 IPR010994 RuvA domain 2-like MB46_05035 c86545fc755150427c76e574b5950b54 662 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 11 468 1.0E-120 T 14-10-2018 IPR004791 UvrABC system, subunit C GO:0006289|GO:0009380|GO:0009381 MB46_05035 c86545fc755150427c76e574b5950b54 662 SUPERFAMILY SSF46600 195 245 1.31E-12 T 14-10-2018 IPR036876 UVR domain superfamily MB46_05035 c86545fc755150427c76e574b5950b54 662 Gene3D G3DSA:3.30.420.340 387 580 1.1E-51 T 14-10-2018 IPR038476 UvrC homology region 2 superfamily MB46_05035 c86545fc755150427c76e574b5950b54 662 Pfam PF02151 UvrB/uvrC motif 207 241 4.4E-10 T 14-10-2018 IPR001943 UVR domain GO:0005515 MB46_05035 c86545fc755150427c76e574b5950b54 662 Gene3D G3DSA:4.10.860.10 199 244 2.2E-6 T 14-10-2018 MB46_05035 c86545fc755150427c76e574b5950b54 662 Gene3D G3DSA:1.10.150.20 581 640 1.8E-19 T 14-10-2018 MB46_05035 c86545fc755150427c76e574b5950b54 662 SMART SM00465 17 99 1.8E-17 T 14-10-2018 IPR000305 GIY-YIG endonuclease MB46_05035 c86545fc755150427c76e574b5950b54 662 Pfam PF01541 GIY-YIG catalytic domain 19 94 1.0E-9 T 14-10-2018 IPR000305 GIY-YIG endonuclease MB46_18770 b5ec50ad59cb46228b7680228ac292cc 309 PRINTS PR00146 Dihydrodipicolinate synthase signature 134 151 3.7E-8 T 14-10-2018 IPR002220 DapA-like GO:0016829 MB46_18770 b5ec50ad59cb46228b7680228ac292cc 309 PRINTS PR00146 Dihydrodipicolinate synthase signature 77 95 3.7E-8 T 14-10-2018 IPR002220 DapA-like GO:0016829 MB46_18770 b5ec50ad59cb46228b7680228ac292cc 309 PRINTS PR00146 Dihydrodipicolinate synthase signature 41 62 3.7E-8 T 14-10-2018 IPR002220 DapA-like GO:0016829 MB46_18770 b5ec50ad59cb46228b7680228ac292cc 309 Pfam PF00701 Dihydrodipicolinate synthetase family 8 304 1.3E-43 T 14-10-2018 IPR002220 DapA-like GO:0016829 MB46_18770 b5ec50ad59cb46228b7680228ac292cc 309 SMART SM01130 7 307 2.1E-71 T 14-10-2018 IPR002220 DapA-like GO:0016829 MB46_18770 b5ec50ad59cb46228b7680228ac292cc 309 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 139 169 - T 14-10-2018 IPR020625 Schiff base-forming aldolase, active site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 MB46_18770 b5ec50ad59cb46228b7680228ac292cc 309 Gene3D G3DSA:3.20.20.70 4 308 1.0E-86 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MB46_18770 b5ec50ad59cb46228b7680228ac292cc 309 SUPERFAMILY SSF51569 3 308 8.69E-72 T 14-10-2018 MB46_18770 b5ec50ad59cb46228b7680228ac292cc 309 PIRSF PIRSF001365 3 309 2.7E-69 T 14-10-2018 IPR002220 DapA-like GO:0016829 MB46_17925 c35af7ac1b296d957e4bb7987a832a9f 417 Gene3D G3DSA:1.20.1740.10 7 417 1.1E-79 T 14-10-2018 MB46_17925 c35af7ac1b296d957e4bb7987a832a9f 417 PIRSF PIRSF006060 1 412 9.6E-65 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 MB46_17925 c35af7ac1b296d957e4bb7987a832a9f 417 Pfam PF13520 Amino acid permease 11 386 1.2E-42 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 MB46_01470 431ac9937f92b1a096d2c96e28cd0875 279 Pfam PF13020 Domain of unknown function (DUF3883) 160 251 7.6E-19 T 14-10-2018 IPR024975 Domain of unknown function DUF3883 MB46_06330 57c635c48bfb28f0196d0c5ec97784a2 326 SUPERFAMILY SSF161098 95 325 7.63E-15 T 14-10-2018 IPR035906 MetI-like superfamily MB46_06330 57c635c48bfb28f0196d0c5ec97784a2 326 Gene3D G3DSA:1.10.3720.10 91 318 1.0E-17 T 14-10-2018 IPR035906 MetI-like superfamily MB46_06330 57c635c48bfb28f0196d0c5ec97784a2 326 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 119 326 1.6E-41 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_18370 12d082165f1ddddab759a518ff8fb764 482 Gene3D G3DSA:1.20.1250.20 260 469 1.5E-19 T 14-10-2018 MB46_18370 12d082165f1ddddab759a518ff8fb764 482 SUPERFAMILY SSF103473 204 465 1.7E-28 T 14-10-2018 IPR036259 MFS transporter superfamily MB46_18370 12d082165f1ddddab759a518ff8fb764 482 Pfam PF07690 Major Facilitator Superfamily 19 412 2.5E-47 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MB46_18370 12d082165f1ddddab759a518ff8fb764 482 Gene3D G3DSA:1.20.1250.20 7 203 6.7E-41 T 14-10-2018 MB46_18370 12d082165f1ddddab759a518ff8fb764 482 SUPERFAMILY SSF103473 8 194 8.11E-40 T 14-10-2018 IPR036259 MFS transporter superfamily MB46_00080 3bee2562431370c82e20d55a971e431a 404 Gene3D G3DSA:3.20.20.140 54 358 3.3E-92 T 14-10-2018 MB46_00080 3bee2562431370c82e20d55a971e431a 404 Pfam PF07969 Amidohydrolase family 151 349 4.9E-15 T 14-10-2018 IPR013108 Amidohydrolase 3 MB46_00080 3bee2562431370c82e20d55a971e431a 404 Gene3D G3DSA:2.30.40.10 6 398 3.3E-92 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 MB46_00080 3bee2562431370c82e20d55a971e431a 404 SUPERFAMILY SSF51338 18 61 9.26E-7 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 MB46_00080 3bee2562431370c82e20d55a971e431a 404 SUPERFAMILY SSF51556 54 348 4.79E-69 T 14-10-2018 IPR032466 Metal-dependent hydrolase MB46_05725 f14498936f7fb4a8b1885253a1529687 304 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 289 5.3E-11 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_05725 f14498936f7fb4a8b1885253a1529687 304 Gene3D G3DSA:1.10.3720.10 27 295 3.9E-50 T 14-10-2018 IPR035906 MetI-like superfamily MB46_05725 f14498936f7fb4a8b1885253a1529687 304 SUPERFAMILY SSF161098 33 304 2.71E-51 T 14-10-2018 IPR035906 MetI-like superfamily MB46_03595 490f2519feb97bc2ec3a5f587985449a 760 Gene3D G3DSA:3.30.470.130 2 465 1.8E-178 T 14-10-2018 MB46_03595 490f2519feb97bc2ec3a5f587985449a 760 Pfam PF00364 Biotin-requiring enzyme 677 741 5.0E-15 T 14-10-2018 IPR000089 Biotin/lipoyl attachment MB46_03595 490f2519feb97bc2ec3a5f587985449a 760 SUPERFAMILY SSF52440 4 116 4.32E-46 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily MB46_03595 490f2519feb97bc2ec3a5f587985449a 760 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 156 170 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MB46_03595 490f2519feb97bc2ec3a5f587985449a 760 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 118 337 9.9E-67 T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MB46_03595 490f2519feb97bc2ec3a5f587985449a 760 SUPERFAMILY SSF56059 86 362 7.95E-58 T 14-10-2018 MB46_03595 490f2519feb97bc2ec3a5f587985449a 760 SUPERFAMILY SSF51246 346 463 5.76E-33 T 14-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 MB46_03595 490f2519feb97bc2ec3a5f587985449a 760 SUPERFAMILY SSF51230 674 742 2.22E-16 T 14-10-2018 IPR011053 Single hybrid motif MB46_03595 490f2519feb97bc2ec3a5f587985449a 760 Pfam PF00289 Biotin carboxylase, N-terminal domain 5 113 1.3E-43 T 14-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MB46_03595 490f2519feb97bc2ec3a5f587985449a 760 Gene3D G3DSA:2.40.50.100 675 742 4.3E-19 T 14-10-2018 MB46_03595 490f2519feb97bc2ec3a5f587985449a 760 SMART SM00878 351 459 6.1E-44 T 14-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MB46_03595 490f2519feb97bc2ec3a5f587985449a 760 Pfam PF02785 Biotin carboxylase C-terminal domain 351 460 3.1E-30 T 14-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MB46_03595 490f2519feb97bc2ec3a5f587985449a 760 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 700 717 - T 14-10-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MB46_03595 490f2519feb97bc2ec3a5f587985449a 760 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 296 303 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MB46_14345 b41b8129ac082561ed260f14f108fac8 298 SMART SM00014 102 208 0.001 T 14-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MB46_14345 b41b8129ac082561ed260f14f108fac8 298 Pfam PF01569 PAP2 superfamily 138 212 3.7E-9 T 14-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MB46_14345 b41b8129ac082561ed260f14f108fac8 298 Gene3D G3DSA:1.20.144.10 124 233 1.5E-11 T 14-10-2018 MB46_14345 b41b8129ac082561ed260f14f108fac8 298 SUPERFAMILY SSF48317 31 218 3.27E-17 T 14-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily MB46_11760 aeb61b7b9052ff247b7c92ce434371ed 317 Gene3D G3DSA:3.40.50.10330 15 153 9.6E-20 T 14-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 MB46_11760 aeb61b7b9052ff247b7c92ce434371ed 317 SUPERFAMILY SSF111331 21 315 3.6E-59 T 14-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily MB46_11760 aeb61b7b9052ff247b7c92ce434371ed 317 Gene3D G3DSA:2.60.200.40 156 308 2.8E-36 T 14-10-2018 MB46_11760 aeb61b7b9052ff247b7c92ce434371ed 317 Pfam PF00781 Diacylglycerol kinase catalytic domain 40 134 8.6E-17 T 14-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 MB46_04855 cd2b6d64c22b3ac49a58584f3988053b 358 Pfam PF00356 Bacterial regulatory proteins, lacI family 5 50 2.1E-13 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MB46_04855 cd2b6d64c22b3ac49a58584f3988053b 358 SMART SM00354 2 73 7.0E-22 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MB46_04855 cd2b6d64c22b3ac49a58584f3988053b 358 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 14-10-2018 MB46_04855 cd2b6d64c22b3ac49a58584f3988053b 358 Gene3D G3DSA:3.40.50.2300 173 315 1.2E-58 T 14-10-2018 MB46_04855 cd2b6d64c22b3ac49a58584f3988053b 358 SUPERFAMILY SSF47413 3 61 1.74E-12 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MB46_04855 cd2b6d64c22b3ac49a58584f3988053b 358 Gene3D G3DSA:1.10.260.40 2 57 1.5E-16 T 14-10-2018 MB46_04855 cd2b6d64c22b3ac49a58584f3988053b 358 Pfam PF13377 Periplasmic binding protein-like domain 183 331 1.8E-24 T 14-10-2018 MB46_04855 cd2b6d64c22b3ac49a58584f3988053b 358 Gene3D G3DSA:3.40.50.2300 58 330 1.2E-58 T 14-10-2018 MB46_04855 cd2b6d64c22b3ac49a58584f3988053b 358 SUPERFAMILY SSF53822 63 351 4.71E-46 T 14-10-2018 IPR028082 Periplasmic binding protein-like I MB46_08185 7d0aea48215821dd6814b0a7f2004778 1169 Pfam PF01336 OB-fold nucleic acid binding domain 1009 1086 3.1E-7 T 14-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 MB46_08185 7d0aea48215821dd6814b0a7f2004778 1169 SMART SM00481 1 58 7.0E-12 T 14-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal MB46_08185 7d0aea48215821dd6814b0a7f2004778 1169 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 1 1046 0.0 T 14-10-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MB46_08185 7d0aea48215821dd6814b0a7f2004778 1169 SUPERFAMILY SSF89550 3 276 2.35E-25 T 14-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 MB46_08185 7d0aea48215821dd6814b0a7f2004778 1169 Pfam PF14579 Helix-hairpin-helix motif 818 907 1.6E-23 T 14-10-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MB46_08185 7d0aea48215821dd6814b0a7f2004778 1169 Pfam PF02811 PHP domain 1 180 4.3E-34 T 14-10-2018 IPR004013 PHP domain GO:0003824 MB46_08185 7d0aea48215821dd6814b0a7f2004778 1169 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 305 745 7.8E-161 T 14-10-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MB46_08185 7d0aea48215821dd6814b0a7f2004778 1169 Gene3D G3DSA:1.10.10.1600 438 524 2.2E-13 T 14-10-2018 MB46_08185 7d0aea48215821dd6814b0a7f2004778 1169 Gene3D G3DSA:3.20.20.140 1 283 6.8E-85 T 14-10-2018 MB46_03895 9cf4aa3bafe1ed39be673ae265baa356 164 Pfam PF02464 Competence-damaged protein 9 155 5.8E-49 T 14-10-2018 IPR008136 CinA, C-terminal MB46_03895 9cf4aa3bafe1ed39be673ae265baa356 164 Gene3D G3DSA:3.90.950.20 2 159 8.9E-54 T 14-10-2018 IPR036653 CinA-like, C-terminal MB46_03895 9cf4aa3bafe1ed39be673ae265baa356 164 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 15 153 7.5E-39 T 14-10-2018 IPR008136 CinA, C-terminal MB46_03895 9cf4aa3bafe1ed39be673ae265baa356 164 SUPERFAMILY SSF142433 8 156 1.57E-46 T 14-10-2018 IPR036653 CinA-like, C-terminal MB46_17095 adc156ffff905a552b52152d3be6174e 340 Gene3D G3DSA:1.10.260.40 1 59 9.0E-22 T 14-10-2018 MB46_17095 adc156ffff905a552b52152d3be6174e 340 Gene3D G3DSA:3.40.50.2300 60 313 4.1E-54 T 14-10-2018 MB46_17095 adc156ffff905a552b52152d3be6174e 340 Gene3D G3DSA:3.40.50.2300 171 296 4.1E-54 T 14-10-2018 MB46_17095 adc156ffff905a552b52152d3be6174e 340 Pfam PF00356 Bacterial regulatory proteins, lacI family 8 53 1.9E-14 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MB46_17095 adc156ffff905a552b52152d3be6174e 340 ProSitePatterns PS00356 LacI-type HTH domain signature. 9 27 - T 14-10-2018 MB46_17095 adc156ffff905a552b52152d3be6174e 340 SUPERFAMILY SSF53822 80 339 8.57E-49 T 14-10-2018 IPR028082 Periplasmic binding protein-like I MB46_17095 adc156ffff905a552b52152d3be6174e 340 SMART SM00354 6 76 1.4E-20 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MB46_17095 adc156ffff905a552b52152d3be6174e 340 SUPERFAMILY SSF47413 5 63 2.22E-16 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MB46_17095 adc156ffff905a552b52152d3be6174e 340 Pfam PF13377 Periplasmic binding protein-like domain 180 336 4.7E-27 T 14-10-2018 MB46_13615 5122178a758371a362828453525ab3c7 339 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 42 326 3.1E-6 T 14-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 MB46_13615 5122178a758371a362828453525ab3c7 339 Gene3D G3DSA:3.40.50.720 17 321 1.3E-90 T 14-10-2018 MB46_13615 5122178a758371a362828453525ab3c7 339 SUPERFAMILY SSF51735 115 300 3.21E-42 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_13615 5122178a758371a362828453525ab3c7 339 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 210 232 - T 14-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site MB46_13615 5122178a758371a362828453525ab3c7 339 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 156 299 1.8E-44 T 14-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 MB46_13615 5122178a758371a362828453525ab3c7 339 SUPERFAMILY SSF52283 38 123 1.46E-9 T 14-10-2018 MB46_13615 5122178a758371a362828453525ab3c7 339 Gene3D G3DSA:3.40.50.720 111 298 1.3E-90 T 14-10-2018 MB46_15450 43fe9632ed70f44aab6835e901f54ae6 310 Gene3D G3DSA:3.40.50.720 9 173 3.6E-35 T 14-10-2018 MB46_15450 43fe9632ed70f44aab6835e901f54ae6 310 Pfam PF10727 Rossmann-like domain 6 126 9.1E-46 T 14-10-2018 IPR019665 Putative oxidoreductase/dehydrogenase, Rossmann-like domain MB46_15450 43fe9632ed70f44aab6835e901f54ae6 310 Pfam PF10728 Domain of unknown function (DUF2520) 143 272 4.3E-39 T 14-10-2018 IPR018931 Domain of unknown function DUF2520 MB46_15450 43fe9632ed70f44aab6835e901f54ae6 310 Gene3D G3DSA:1.10.1040.20 175 271 7.0E-18 T 14-10-2018 IPR037108 TM1727-like, C-terminal domain superfamily MB46_15450 43fe9632ed70f44aab6835e901f54ae6 310 SUPERFAMILY SSF48179 176 279 1.02E-22 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MB46_15450 43fe9632ed70f44aab6835e901f54ae6 310 SUPERFAMILY SSF51735 12 173 1.94E-25 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_03150 f3b779dee62e35a5b8c34639d5c0944f 263 Gene3D G3DSA:1.10.10.10 4 88 6.4E-6 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_03150 f3b779dee62e35a5b8c34639d5c0944f 263 Pfam PF08220 DeoR-like helix-turn-helix domain 6 58 6.5E-17 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MB46_03150 f3b779dee62e35a5b8c34639d5c0944f 263 SMART SM01134 72 241 2.2E-52 T 14-10-2018 MB46_03150 f3b779dee62e35a5b8c34639d5c0944f 263 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 14-10-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 MB46_03150 f3b779dee62e35a5b8c34639d5c0944f 263 Pfam PF00455 DeoR C terminal sensor domain 74 240 8.3E-43 T 14-10-2018 IPR014036 DeoR C-terminal sensor domain MB46_03150 f3b779dee62e35a5b8c34639d5c0944f 263 SMART SM00420 6 58 1.3E-16 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MB46_03150 f3b779dee62e35a5b8c34639d5c0944f 263 SUPERFAMILY SSF100950 74 232 4.08E-25 T 14-10-2018 IPR037171 NagB/RpiA transferase-like MB46_03150 f3b779dee62e35a5b8c34639d5c0944f 263 SUPERFAMILY SSF46785 3 59 5.3E-12 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_03150 f3b779dee62e35a5b8c34639d5c0944f 263 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 2.2E-8 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MB46_03150 f3b779dee62e35a5b8c34639d5c0944f 263 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 2.2E-8 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MB46_04370 9971d0a85b1e1339fe638ef6cf74dfe7 309 SUPERFAMILY SSF51621 6 294 3.32E-96 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 MB46_04370 9971d0a85b1e1339fe638ef6cf74dfe7 309 Hamap MF_01939 2-methylisocitrate lyase [prpB]. 9 295 45.227 T 14-10-2018 IPR012695 2-methylisocitrate lyase GO:0019629|GO:0046421 KEGG: 00640+4.1.3.30|MetaCyc: PWY-5747 MB46_04370 9971d0a85b1e1339fe638ef6cf74dfe7 309 Gene3D G3DSA:3.20.20.60 1 298 6.8E-102 T 14-10-2018 MB46_04370 9971d0a85b1e1339fe638ef6cf74dfe7 309 ProSitePatterns PS00161 Isocitrate lyase signature. 124 129 - T 14-10-2018 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824 MB46_04370 9971d0a85b1e1339fe638ef6cf74dfe7 309 TIGRFAM TIGR02317 prpB: methylisocitrate lyase 12 294 2.8E-119 T 14-10-2018 IPR012695 2-methylisocitrate lyase GO:0019629|GO:0046421 KEGG: 00640+4.1.3.30|MetaCyc: PWY-5747 MB46_04370 9971d0a85b1e1339fe638ef6cf74dfe7 309 Pfam PF13714 Phosphoenolpyruvate phosphomutase 16 257 1.2E-53 T 14-10-2018 MB46_03390 f416f2580f25e80341d51b29c6a17732 362 Gene3D G3DSA:1.10.443.10 158 355 3.5E-34 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 MB46_03390 f416f2580f25e80341d51b29c6a17732 362 Gene3D G3DSA:1.10.150.130 44 153 6.3E-15 T 14-10-2018 IPR010998 Integrase/recombinase, N-terminal MB46_03390 f416f2580f25e80341d51b29c6a17732 362 SUPERFAMILY SSF56349 50 345 3.92E-49 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MB46_03390 f416f2580f25e80341d51b29c6a17732 362 Pfam PF00589 Phage integrase family 188 346 2.0E-15 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MB46_04705 d0602a2d4e41812d051eaecbe9e059cf 128 Pfam PF01521 Iron-sulphur cluster biosynthesis 26 125 2.8E-17 T 14-10-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 MB46_04705 d0602a2d4e41812d051eaecbe9e059cf 128 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 110 127 - T 14-10-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 MB46_04705 d0602a2d4e41812d051eaecbe9e059cf 128 Gene3D G3DSA:2.60.300.12 23 128 1.3E-28 T 14-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 MB46_04705 d0602a2d4e41812d051eaecbe9e059cf 128 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 25 128 5.2E-34 T 14-10-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 MB46_04705 d0602a2d4e41812d051eaecbe9e059cf 128 SUPERFAMILY SSF89360 24 117 3.73E-27 T 14-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 MB46_08540 a37f6a5de41fd33eb86c85fd2564a232 302 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 9 92 7.4E-28 T 14-10-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 MB46_08540 a37f6a5de41fd33eb86c85fd2564a232 302 SUPERFAMILY SSF51735 110 264 1.78E-24 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_08540 a37f6a5de41fd33eb86c85fd2564a232 302 Gene3D G3DSA:3.40.50.10860 8 264 1.9E-70 T 14-10-2018 MB46_08540 a37f6a5de41fd33eb86c85fd2564a232 302 SUPERFAMILY SSF53223 5 109 2.24E-29 T 14-10-2018 MB46_08540 a37f6a5de41fd33eb86c85fd2564a232 302 Gene3D G3DSA:3.40.50.720 110 255 1.9E-70 T 14-10-2018 MB46_04105 ddb3e1385787b92adc9e869357c6e8ed 338 Gene3D G3DSA:3.40.50.720 18 327 4.3E-51 T 14-10-2018 MB46_04105 ddb3e1385787b92adc9e869357c6e8ed 338 Gene3D G3DSA:3.30.360.10 162 310 4.3E-51 T 14-10-2018 MB46_04105 ddb3e1385787b92adc9e869357c6e8ed 338 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 22 141 1.2E-6 T 14-10-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 MB46_04105 ddb3e1385787b92adc9e869357c6e8ed 338 Pfam PF00742 Homoserine dehydrogenase 157 327 5.4E-28 T 14-10-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 MB46_04105 ddb3e1385787b92adc9e869357c6e8ed 338 SUPERFAMILY SSF51735 14 160 4.0E-9 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_04105 ddb3e1385787b92adc9e869357c6e8ed 338 SUPERFAMILY SSF55347 152 310 3.07E-25 T 14-10-2018 MB46_04105 ddb3e1385787b92adc9e869357c6e8ed 338 PIRSF PIRSF036497 13 335 2.4E-67 T 14-10-2018 IPR022697 Homoserine dehydrogenase lacking ACT domain GO:0004412 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 MB46_16640 801990ef93ac385b7f68c11fb4f702f6 208 SUPERFAMILY SSF55729 17 188 2.05E-38 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase MB46_16640 801990ef93ac385b7f68c11fb4f702f6 208 Gene3D G3DSA:3.40.630.30 9 205 3.7E-39 T 14-10-2018 MB46_16640 801990ef93ac385b7f68c11fb4f702f6 208 Pfam PF13302 Acetyltransferase (GNAT) domain 24 164 2.0E-22 T 14-10-2018 IPR000182 GNAT domain MB46_05910 e7018aca58f5e1420826db2f7111e623 210 Gene3D G3DSA:3.40.430.10 2 190 8.9E-43 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 MB46_05910 e7018aca58f5e1420826db2f7111e623 210 SUPERFAMILY SSF53597 1 191 1.28E-28 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 MB46_05910 e7018aca58f5e1420826db2f7111e623 210 Pfam PF01872 RibD C-terminal domain 2 186 6.9E-27 T 14-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 MB46_12170 6d0ce0e4b2d30f3984aba239d91c5653 329 SUPERFAMILY SSF51679 4 320 2.62E-75 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 MB46_12170 6d0ce0e4b2d30f3984aba239d91c5653 329 Gene3D G3DSA:3.20.20.30 1 328 5.0E-90 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 MB46_12170 6d0ce0e4b2d30f3984aba239d91c5653 329 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 5 320 1.1E-119 T 14-10-2018 IPR019949 Luciferase family oxidoreductase, group 1 MB46_12170 6d0ce0e4b2d30f3984aba239d91c5653 329 Pfam PF00296 Luciferase-like monooxygenase 13 293 3.2E-36 T 14-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MB46_07985 5c6152824d82e51570c8b8732957a0df 359 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 1 215 2.9E-62 T 14-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 MB46_07985 5c6152824d82e51570c8b8732957a0df 359 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 4 321 2.3E-101 T 14-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 MB46_07985 5c6152824d82e51570c8b8732957a0df 359 PIRSF PIRSF000267 1 335 2.9E-115 T 14-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 MB46_05580 a64040068b1b62dff07c76fa0273f01c 102 SUPERFAMILY SSF54909 1 95 9.58E-26 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel MB46_05580 a64040068b1b62dff07c76fa0273f01c 102 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 75 1.2E-10 T 14-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain MB46_05580 a64040068b1b62dff07c76fa0273f01c 102 Gene3D G3DSA:3.30.70.100 1 95 2.9E-34 T 14-10-2018 MB46_19080 873716ce0753f020ada2228c8336e553 474 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 4 471 6.6E-133 T 14-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 MB46_19080 873716ce0753f020ada2228c8336e553 474 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 3 473 35.096 T 14-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 MB46_19080 873716ce0753f020ada2228c8336e553 474 SUPERFAMILY SSF52374 9 315 7.78E-83 T 14-10-2018 MB46_19080 873716ce0753f020ada2228c8336e553 474 SUPERFAMILY SSF47323 347 472 1.07E-30 T 14-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 MB46_19080 873716ce0753f020ada2228c8336e553 474 SMART SM00840 351 421 2.2E-14 T 14-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 MB46_19080 873716ce0753f020ada2228c8336e553 474 Pfam PF09190 DALR domain 351 405 9.1E-12 T 14-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 MB46_19080 873716ce0753f020ada2228c8336e553 474 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 62 71 1.1E-24 T 14-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 MB46_19080 873716ce0753f020ada2228c8336e553 474 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 227 248 1.1E-24 T 14-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 MB46_19080 873716ce0753f020ada2228c8336e553 474 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 196 214 1.1E-24 T 14-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 MB46_19080 873716ce0753f020ada2228c8336e553 474 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 26 37 1.1E-24 T 14-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 MB46_19080 873716ce0753f020ada2228c8336e553 474 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 16 316 6.8E-114 T 14-10-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 MB46_19080 873716ce0753f020ada2228c8336e553 474 Gene3D G3DSA:1.20.120.640 311 473 1.9E-35 T 14-10-2018 MB46_19080 873716ce0753f020ada2228c8336e553 474 Gene3D G3DSA:3.40.50.620 1 309 3.2E-116 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MB46_14195 9d8dd659bd389d1a059a084a5da7ff27 251 SUPERFAMILY SSF52540 14 225 6.1E-63 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_14195 9d8dd659bd389d1a059a084a5da7ff27 251 Pfam PF00005 ABC transporter 30 163 1.2E-29 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_14195 9d8dd659bd389d1a059a084a5da7ff27 251 SMART SM00382 39 213 2.3E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_14195 9d8dd659bd389d1a059a084a5da7ff27 251 Gene3D G3DSA:3.40.50.300 12 249 3.1E-62 T 14-10-2018 MB46_14195 9d8dd659bd389d1a059a084a5da7ff27 251 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_16235 61d6ea057f4bf536369e10de49374a97 267 Pfam PF12401 Protein of unknown function (DUF2662) 4 117 2.1E-35 T 14-10-2018 IPR022128 Domain of unknown function DUF3662 MB46_16235 61d6ea057f4bf536369e10de49374a97 267 Pfam PF16697 Inner membrane component of T3SS, cytoplasmic domain 176 256 6.1E-17 T 14-10-2018 IPR032030 YscD, cytoplasmic domain MB46_16235 61d6ea057f4bf536369e10de49374a97 267 Gene3D G3DSA:2.60.200.20 141 260 8.1E-25 T 14-10-2018 MB46_16235 61d6ea057f4bf536369e10de49374a97 267 SUPERFAMILY SSF49879 134 258 1.65E-24 T 14-10-2018 IPR008984 SMAD/FHA domain superfamily GO:0005515 MB46_16235 61d6ea057f4bf536369e10de49374a97 267 Gene3D G3DSA:3.30.2320.60 1 125 8.1E-35 T 14-10-2018 MB46_16235 61d6ea057f4bf536369e10de49374a97 267 SMART SM00240 185 235 2.0E-13 T 14-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 MB46_05410 eb17808333e1caac6603bea4ca006200 271 Gene3D G3DSA:3.60.20.10 49 271 3.8E-79 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MB46_05410 eb17808333e1caac6603bea4ca006200 271 Pfam PF00227 Proteasome subunit 47 226 1.8E-31 T 14-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 MB46_05410 eb17808333e1caac6603bea4ca006200 271 Hamap MF_02113_B Proteasome subunit beta [prcB]. 4 270 45.992 T 14-10-2018 IPR022483 Peptidase T1A, proteasome beta-subunit, actinobacteria GO:0004298|GO:0005839|GO:0010498 MB46_05410 eb17808333e1caac6603bea4ca006200 271 SUPERFAMILY SSF56235 37 257 1.49E-53 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MB46_05410 eb17808333e1caac6603bea4ca006200 271 TIGRFAM TIGR03690 20S_bact_beta: proteasome, beta subunit 45 265 3.2E-110 T 14-10-2018 IPR022483 Peptidase T1A, proteasome beta-subunit, actinobacteria GO:0004298|GO:0005839|GO:0010498 MB46_14430 d2240f73f372fd6fd03a3d5b896eea36 291 Pfam PF05138 Phenylacetic acid catabolic protein 43 291 7.6E-87 T 14-10-2018 IPR007814 1,2-phenylacetyl-CoA epoxidase, subunit A/C GO:0010124 MB46_14430 d2240f73f372fd6fd03a3d5b896eea36 291 Gene3D G3DSA:1.20.1260.10 38 291 8.7E-94 T 14-10-2018 IPR012347 Ferritin-like MB46_14430 d2240f73f372fd6fd03a3d5b896eea36 291 SUPERFAMILY SSF47240 50 285 4.6E-73 T 14-10-2018 IPR009078 Ferritin-like superfamily MB46_14430 d2240f73f372fd6fd03a3d5b896eea36 291 PIRSF PIRSF037834 40 291 4.1E-93 T 14-10-2018 IPR011882 1,2-phenylacetyl-CoA epoxidase, subunit C GO:0010124 MB46_14430 d2240f73f372fd6fd03a3d5b896eea36 291 TIGRFAM TIGR02158 PA_CoA_Oxy3: phenylacetate-CoA oxygenase, PaaI subunit 57 291 2.8E-89 T 14-10-2018 IPR011882 1,2-phenylacetyl-CoA epoxidase, subunit C GO:0010124 MB46_04830 8d8d54f31f7a5c0a1104f0bbfb5d5e3f 206 Gene3D G3DSA:3.90.870.10 1 206 5.7E-58 T 14-10-2018 MB46_04830 8d8d54f31f7a5c0a1104f0bbfb5d5e3f 206 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 7 201 6.5E-55 T 14-10-2018 IPR006070 YrdC-like domain GO:0003725 MB46_04830 8d8d54f31f7a5c0a1104f0bbfb5d5e3f 206 SUPERFAMILY SSF55821 1 204 3.97E-59 T 14-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily MB46_04830 8d8d54f31f7a5c0a1104f0bbfb5d5e3f 206 Pfam PF01300 Telomere recombination 23 198 5.7E-43 T 14-10-2018 IPR006070 YrdC-like domain GO:0003725 MB46_17625 f0a949c9e7dda8d80e249dbbf15e3a27 469 SUPERFAMILY SSF55347 155 356 2.18E-28 T 14-10-2018 MB46_17625 f0a949c9e7dda8d80e249dbbf15e3a27 469 SUPERFAMILY SSF51735 14 181 1.12E-38 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_17625 f0a949c9e7dda8d80e249dbbf15e3a27 469 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 21 150 9.2E-18 T 14-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 MB46_17625 f0a949c9e7dda8d80e249dbbf15e3a27 469 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 162 240 1.4E-18 T 14-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 MB46_17625 f0a949c9e7dda8d80e249dbbf15e3a27 469 Gene3D G3DSA:3.40.50.720 15 152 1.4E-25 T 14-10-2018 MB46_15740 ce7a2a622ab437c413b80cdfec5bf6ed 509 Pfam PF13183 4Fe-4S dicluster domain 327 395 4.2E-9 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MB46_15740 ce7a2a622ab437c413b80cdfec5bf6ed 509 TIGRFAM TIGR00273 TIGR00273: iron-sulfur cluster-binding protein 35 476 1.9E-136 T 14-10-2018 IPR004452 4Fe-4S binding protein GO:0019516 MB46_15740 ce7a2a622ab437c413b80cdfec5bf6ed 509 Pfam PF11870 Domain of unknown function (DUF3390) 417 491 5.7E-7 T 14-10-2018 IPR024569 4Fe-4S binding protein, C-terminal MB46_15740 ce7a2a622ab437c413b80cdfec5bf6ed 509 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 329 340 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MB46_15740 ce7a2a622ab437c413b80cdfec5bf6ed 509 Gene3D G3DSA:3.40.50.10420 143 297 7.3E-8 T 14-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily MB46_15740 ce7a2a622ab437c413b80cdfec5bf6ed 509 SUPERFAMILY SSF100950 80 311 3.6E-35 T 14-10-2018 IPR037171 NagB/RpiA transferase-like MB46_15740 ce7a2a622ab437c413b80cdfec5bf6ed 509 Pfam PF02589 LUD domain 86 296 1.6E-45 T 14-10-2018 IPR003741 LUD domain MB46_15740 ce7a2a622ab437c413b80cdfec5bf6ed 509 SUPERFAMILY SSF54862 308 413 5.44E-14 T 14-10-2018 MB46_12455 921bd8c376d1bd79ad3ab00adf81d928 224 SUPERFAMILY SSF82153 71 222 3.79E-35 T 14-10-2018 IPR036378 FAS1 domain superfamily MB46_12455 921bd8c376d1bd79ad3ab00adf81d928 224 Pfam PF02469 Fasciclin domain 111 221 1.3E-27 T 14-10-2018 IPR000782 FAS1 domain MB46_12455 921bd8c376d1bd79ad3ab00adf81d928 224 SMART SM00554 127 222 1.3E-28 T 14-10-2018 IPR000782 FAS1 domain MB46_12455 921bd8c376d1bd79ad3ab00adf81d928 224 Gene3D G3DSA:2.30.180.10 61 223 1.7E-53 T 14-10-2018 IPR036378 FAS1 domain superfamily MB46_02280 4a383f3cf98395fa2db2e24054562c3b 263 SUPERFAMILY SSF56281 20 261 7.31E-42 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MB46_02280 4a383f3cf98395fa2db2e24054562c3b 263 Gene3D G3DSA:3.60.15.10 3 194 1.9E-40 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MB46_02280 4a383f3cf98395fa2db2e24054562c3b 263 Pfam PF00753 Metallo-beta-lactamase superfamily 24 174 2.0E-12 T 14-10-2018 IPR001279 Metallo-beta-lactamase MB46_02280 4a383f3cf98395fa2db2e24054562c3b 263 SMART SM00849 27 189 3.9E-23 T 14-10-2018 IPR001279 Metallo-beta-lactamase MB46_05365 8c113257c6bbe5755f154311b81fdc4d 278 Pfam PF02673 Bacitracin resistance protein BacA 6 266 2.2E-82 T 14-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 MB46_05365 8c113257c6bbe5755f154311b81fdc4d 278 TIGRFAM TIGR00753 undec_PP_bacA: undecaprenyl-diphosphatase UppP 6 264 8.2E-80 T 14-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 MB46_05365 8c113257c6bbe5755f154311b81fdc4d 278 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 1 271 17.801 T 14-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 MB46_00265 459ea71a39ff6ebde6a50b4c374a2698 445 SUPERFAMILY SSF51445 11 335 3.51E-61 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily MB46_00265 459ea71a39ff6ebde6a50b4c374a2698 445 PRINTS PR00740 Glycosyl hydrolase family 27 signature 103 124 4.2E-10 T 14-10-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 MB46_00265 459ea71a39ff6ebde6a50b4c374a2698 445 PRINTS PR00740 Glycosyl hydrolase family 27 signature 9 28 4.2E-10 T 14-10-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 MB46_00265 459ea71a39ff6ebde6a50b4c374a2698 445 PRINTS PR00740 Glycosyl hydrolase family 27 signature 297 318 4.2E-10 T 14-10-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 MB46_00265 459ea71a39ff6ebde6a50b4c374a2698 445 PRINTS PR00740 Glycosyl hydrolase family 27 signature 197 215 4.2E-10 T 14-10-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 MB46_00265 459ea71a39ff6ebde6a50b4c374a2698 445 Pfam PF16499 Alpha galactosidase A 160 330 7.9E-16 T 14-10-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 MB46_00265 459ea71a39ff6ebde6a50b4c374a2698 445 Gene3D G3DSA:3.20.20.70 1 338 3.3E-120 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MB46_00265 459ea71a39ff6ebde6a50b4c374a2698 445 Gene3D G3DSA:2.60.40.1180 353 444 2.0E-9 T 14-10-2018 IPR013780 Glycosyl hydrolase, all-beta MB46_08595 a0c877021004100ee8426974b17e808f 374 Pfam PF01032 FecCD transport family 47 369 2.2E-85 T 14-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 MB46_08595 a0c877021004100ee8426974b17e808f 374 Gene3D G3DSA:1.10.3470.10 32 372 1.8E-96 T 14-10-2018 IPR037294 ABC transporter, BtuC-like MB46_08595 a0c877021004100ee8426974b17e808f 374 SUPERFAMILY SSF81345 31 369 4.32E-76 T 14-10-2018 IPR037294 ABC transporter, BtuC-like MB46_13070 7dca3abf0906460557c5f6b4361ed37a 334 SUPERFAMILY SSF81345 26 329 2.09E-63 T 14-10-2018 IPR037294 ABC transporter, BtuC-like MB46_13070 7dca3abf0906460557c5f6b4361ed37a 334 Gene3D G3DSA:1.10.3470.10 16 332 7.4E-61 T 14-10-2018 IPR037294 ABC transporter, BtuC-like MB46_13070 7dca3abf0906460557c5f6b4361ed37a 334 Pfam PF01032 FecCD transport family 30 329 2.9E-60 T 14-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 MB46_17605 e47e3656abc8939f065124b687a0e8cf 470 Pfam PF00324 Amino acid permease 15 440 3.2E-114 T 14-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 MB46_17605 e47e3656abc8939f065124b687a0e8cf 470 PIRSF PIRSF006060 1 465 1.2E-83 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 MB46_17605 e47e3656abc8939f065124b687a0e8cf 470 ProSitePatterns PS00218 Amino acid permeases signature. 40 70 - T 14-10-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 MB46_17605 e47e3656abc8939f065124b687a0e8cf 470 Gene3D G3DSA:1.20.1740.10 5 462 1.7E-65 T 14-10-2018 MB46_00230 8e854f2efa60826186161440ef15321c 312 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 96 303 1.5E-11 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_00230 8e854f2efa60826186161440ef15321c 312 Gene3D G3DSA:1.10.3720.10 22 303 2.9E-66 T 14-10-2018 IPR035906 MetI-like superfamily MB46_00230 8e854f2efa60826186161440ef15321c 312 SUPERFAMILY SSF161098 29 312 1.64E-54 T 14-10-2018 IPR035906 MetI-like superfamily MB46_03640 ff630ad026154b870e975b89362a6889 442 Gene3D G3DSA:2.30.42.10 183 277 8.9E-18 T 14-10-2018 MB46_03640 ff630ad026154b870e975b89362a6889 442 Pfam PF02163 Peptidase family M50 13 399 3.4E-45 T 14-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 MB46_03640 ff630ad026154b870e975b89362a6889 442 SUPERFAMILY SSF50156 129 241 1.08E-15 T 14-10-2018 IPR036034 PDZ superfamily GO:0005515 MB46_03640 ff630ad026154b870e975b89362a6889 442 Pfam PF13180 PDZ domain 185 240 2.9E-8 T 14-10-2018 IPR001478 PDZ domain GO:0005515 MB46_13345 2cd6ce1d5312c1f6ce91f6da9d647681 158 SUPERFAMILY SSF52080 18 156 2.62E-41 T 14-10-2018 IPR036227 Ribosomal L18e/L15P superfamily MB46_13345 2cd6ce1d5312c1f6ce91f6da9d647681 158 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 40 155 1.5E-32 T 14-10-2018 IPR021131 Ribosomal protein L18e/L15P MB46_13345 2cd6ce1d5312c1f6ce91f6da9d647681 158 ProSitePatterns PS00475 Ribosomal protein L15 signature. 122 152 - T 14-10-2018 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MB46_13345 2cd6ce1d5312c1f6ce91f6da9d647681 158 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 17 158 18.822 T 14-10-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 MB46_13345 2cd6ce1d5312c1f6ce91f6da9d647681 158 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 17 155 3.2E-45 T 14-10-2018 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_13345 2cd6ce1d5312c1f6ce91f6da9d647681 158 Gene3D G3DSA:3.100.10.10 79 158 1.5E-23 T 14-10-2018 MB46_16225 22593aac41cb498899e595139cb315f4 545 SMART SM00331 14 240 1.5E-29 T 14-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MB46_16225 22593aac41cb498899e595139cb315f4 545 SMART SM00332 5 238 1.2E-14 T 14-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MB46_16225 22593aac41cb498899e595139cb315f4 545 SUPERFAMILY SSF81606 8 239 5.89E-59 T 14-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MB46_16225 22593aac41cb498899e595139cb315f4 545 Pfam PF13672 Protein phosphatase 2C 21 203 3.5E-12 T 14-10-2018 MB46_16225 22593aac41cb498899e595139cb315f4 545 Gene3D G3DSA:3.60.40.10 5 241 1.0E-58 T 14-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MB46_01225 bee1f2d6ff9e40ccf34d6cae8a6c11cc 138 Gene3D G3DSA:3.40.50.2300 5 133 1.1E-36 T 14-10-2018 MB46_01225 bee1f2d6ff9e40ccf34d6cae8a6c11cc 138 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 7 130 2.7E-14 T 14-10-2018 IPR023485 Phosphotyrosine protein phosphatase I MB46_01225 bee1f2d6ff9e40ccf34d6cae8a6c11cc 138 SMART SM00226 5 133 1.2E-20 T 14-10-2018 IPR023485 Phosphotyrosine protein phosphatase I MB46_01225 bee1f2d6ff9e40ccf34d6cae8a6c11cc 138 SUPERFAMILY SSF52788 4 130 5.89E-27 T 14-10-2018 IPR036196 Phosphotyrosine protein phosphatase I superfamily MB46_11585 fbf6d04d887e11ad8a6f6f6fa08dc403 541 SUPERFAMILY SSF52540 258 517 1.67E-23 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_11585 fbf6d04d887e11ad8a6f6f6fa08dc403 541 Gene3D G3DSA:3.40.50.300 257 519 6.4E-38 T 14-10-2018 MB46_11585 fbf6d04d887e11ad8a6f6f6fa08dc403 541 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 262 492 2.2E-7 T 14-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain MB46_04870 4fc1e0b20ccb063833ce1a854d4a53c6 302 SUPERFAMILY SSF51658 2 289 6.28E-47 T 14-10-2018 IPR036237 Xylose isomerase-like superfamily MB46_04870 4fc1e0b20ccb063833ce1a854d4a53c6 302 Pfam PF01261 Xylose isomerase-like TIM barrel 40 242 2.4E-19 T 14-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain MB46_04870 4fc1e0b20ccb063833ce1a854d4a53c6 302 Gene3D G3DSA:3.20.20.150 2 293 3.0E-59 T 14-10-2018 MB46_13040 645168fbda54de67de6a20cc21a0924c 98 ProSitePatterns PS00681 Chaperonins cpn10 signature. 5 29 - T 14-10-2018 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 MB46_13040 645168fbda54de67de6a20cc21a0924c 98 Hamap MF_00580 10 kDa chaperonin [groS]. 4 97 25.649 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 MB46_13040 645168fbda54de67de6a20cc21a0924c 98 SMART SM00883 4 96 3.3E-52 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 MB46_13040 645168fbda54de67de6a20cc21a0924c 98 Gene3D G3DSA:2.30.33.40 2 98 3.7E-37 T 14-10-2018 IPR037124 GroES chaperonin superfamily GO:0005737|GO:0006457 MB46_13040 645168fbda54de67de6a20cc21a0924c 98 SUPERFAMILY SSF50129 3 96 4.1E-33 T 14-10-2018 IPR011032 GroES-like superfamily MB46_13040 645168fbda54de67de6a20cc21a0924c 98 PRINTS PR00297 10kDa chaperonin signature 27 48 2.8E-31 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 MB46_13040 645168fbda54de67de6a20cc21a0924c 98 PRINTS PR00297 10kDa chaperonin signature 83 96 2.8E-31 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 MB46_13040 645168fbda54de67de6a20cc21a0924c 98 PRINTS PR00297 10kDa chaperonin signature 62 74 2.8E-31 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 MB46_13040 645168fbda54de67de6a20cc21a0924c 98 PRINTS PR00297 10kDa chaperonin signature 5 20 2.8E-31 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 MB46_13040 645168fbda54de67de6a20cc21a0924c 98 Pfam PF00166 Chaperonin 10 Kd subunit 5 96 2.1E-33 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 MB46_03155 db5f65b7f1a6e8314646274f501089dc 429 TIGRFAM TIGR01413 Dyp_perox_fam: Dyp-type peroxidase family 69 415 7.5E-86 T 14-10-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 MB46_03155 db5f65b7f1a6e8314646274f501089dc 429 SUPERFAMILY SSF54909 64 416 8.76E-86 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel MB46_03155 db5f65b7f1a6e8314646274f501089dc 429 TIGRFAM TIGR01412 tat_substr_1: Tat-translocated enzyme 9 428 7.2E-133 T 14-10-2018 IPR006313 Deferrochelatase/peroxidase EfeB GO:0004601|GO:0015684|GO:0020037|GO:0033212 MB46_03155 db5f65b7f1a6e8314646274f501089dc 429 Pfam PF04261 Dyp-type peroxidase family 69 415 5.5E-98 T 14-10-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 MB46_08070 60f36f7f41393888a373b3fb154a42d6 574 SUPERFAMILY SSF56112 20 269 1.11E-43 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily MB46_08070 60f36f7f41393888a373b3fb154a42d6 574 Gene3D G3DSA:1.10.510.10 19 284 1.1E-41 T 14-10-2018 MB46_08070 60f36f7f41393888a373b3fb154a42d6 574 Pfam PF00069 Protein kinase domain 23 222 2.6E-25 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 MB46_04620 35219a2d920a1b2677ac37415e5b1dd5 258 Gene3D G3DSA:2.40.240.20 1 73 3.1E-20 T 14-10-2018 MB46_04620 35219a2d920a1b2677ac37415e5b1dd5 258 SUPERFAMILY SSF88697 12 73 1.79E-10 T 14-10-2018 IPR015947 PUA-like superfamily MB46_04620 35219a2d920a1b2677ac37415e5b1dd5 258 SUPERFAMILY SSF75217 79 257 8.37E-42 T 14-10-2018 IPR029028 Alpha/beta knot methyltransferases MB46_04620 35219a2d920a1b2677ac37415e5b1dd5 258 PIRSF PIRSF015601 7 257 1.2E-44 T 14-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 MB46_04620 35219a2d920a1b2677ac37415e5b1dd5 258 Pfam PF04452 RNA methyltransferase 24 251 4.5E-54 T 14-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 MB46_04620 35219a2d920a1b2677ac37415e5b1dd5 258 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 21 253 5.6E-32 T 14-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 MB46_04620 35219a2d920a1b2677ac37415e5b1dd5 258 Gene3D G3DSA:3.40.1280.10 79 258 5.1E-49 T 14-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal MB46_19720 0d3d0b44f423a3dd71eae53df1c629f7 399 Pfam PF00665 Integrase core domain 236 343 1.0E-10 T 14-10-2018 IPR001584 Integrase, catalytic core GO:0015074 MB46_19720 0d3d0b44f423a3dd71eae53df1c629f7 399 ProSitePatterns PS01043 Transposases, IS30 family, signature. 330 346 - T 14-10-2018 IPR001598 Transposase, IS30, conserved site GO:0003677|GO:0004803|GO:0006313 MB46_19720 0d3d0b44f423a3dd71eae53df1c629f7 399 Pfam PF13936 Helix-turn-helix domain 67 106 3.5E-12 T 14-10-2018 IPR025246 Transposase IS30-like HTH domain MB46_19720 0d3d0b44f423a3dd71eae53df1c629f7 399 SUPERFAMILY SSF53098 236 383 2.09E-22 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily MB46_02745 55105257b3c504d3589acf33aedc790d 894 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 595 656 2.4E-13 T 14-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MB46_02745 55105257b3c504d3589acf33aedc790d 894 Gene3D G3DSA:3.30.413.10 666 819 3.0E-33 T 14-10-2018 MB46_02745 55105257b3c504d3589acf33aedc790d 894 SUPERFAMILY SSF51905 20 336 3.18E-28 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_02745 55105257b3c504d3589acf33aedc790d 894 Gene3D G3DSA:1.10.10.1100 444 505 5.0E-6 T 14-10-2018 MB46_02745 55105257b3c504d3589acf33aedc790d 894 SUPERFAMILY SSF55124 548 676 4.25E-25 T 14-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MB46_02745 55105257b3c504d3589acf33aedc790d 894 Gene3D G3DSA:3.50.50.60 22 334 2.4E-63 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_02745 55105257b3c504d3589acf33aedc790d 894 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 714 730 - T 14-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MB46_02745 55105257b3c504d3589acf33aedc790d 894 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 303 310 4.9E-11 T 14-10-2018 MB46_02745 55105257b3c504d3589acf33aedc790d 894 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 168 193 4.9E-11 T 14-10-2018 MB46_02745 55105257b3c504d3589acf33aedc790d 894 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 20 42 4.9E-11 T 14-10-2018 MB46_02745 55105257b3c504d3589acf33aedc790d 894 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 256 270 4.9E-11 T 14-10-2018 MB46_02745 55105257b3c504d3589acf33aedc790d 894 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 667 789 1.3E-16 T 14-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MB46_02745 55105257b3c504d3589acf33aedc790d 894 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 255 271 5.8E-22 T 14-10-2018 MB46_02745 55105257b3c504d3589acf33aedc790d 894 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 168 186 5.8E-22 T 14-10-2018 MB46_02745 55105257b3c504d3589acf33aedc790d 894 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 288 310 5.8E-22 T 14-10-2018 MB46_02745 55105257b3c504d3589acf33aedc790d 894 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 118 136 5.8E-22 T 14-10-2018 MB46_02745 55105257b3c504d3589acf33aedc790d 894 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 21 40 5.8E-22 T 14-10-2018 MB46_02745 55105257b3c504d3589acf33aedc790d 894 PRINTS PR00397 Sirohaem Fe-binding site signature 671 689 4.0E-6 T 14-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MB46_02745 55105257b3c504d3589acf33aedc790d 894 PRINTS PR00397 Sirohaem Fe-binding site signature 714 732 4.0E-6 T 14-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MB46_02745 55105257b3c504d3589acf33aedc790d 894 PIRSF PIRSF037149 14 871 0.0 T 14-10-2018 IPR017121 Nitrite reductase [NAD(P)H], large subunit GO:0042128 MB46_02745 55105257b3c504d3589acf33aedc790d 894 SUPERFAMILY SSF56014 668 842 3.01E-47 T 14-10-2018 MB46_02745 55105257b3c504d3589acf33aedc790d 894 Pfam PF04324 BFD-like [2Fe-2S] binding domain 444 499 4.1E-9 T 14-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain MB46_02745 55105257b3c504d3589acf33aedc790d 894 TIGRFAM TIGR02374 nitri_red_nirB: nitrite reductase [NAD(P)H], large subunit 21 836 6.9E-261 T 14-10-2018 IPR012744 Nitrite reductase [NAD(P)H] large subunit, NirB GO:0008942|GO:0042128|GO:0050660|GO:0050661|GO:0055114 MB46_02745 55105257b3c504d3589acf33aedc790d 894 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 20 310 1.5E-45 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MB46_02745 55105257b3c504d3589acf33aedc790d 894 Gene3D G3DSA:3.50.50.60 131 262 2.4E-63 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_14365 4536f8c26f05c141d075eb30b01c0133 356 Pfam PF02780 Transketolase, C-terminal domain 223 344 2.7E-36 T 14-10-2018 IPR033248 Transketolase, C-terminal domain MB46_14365 4536f8c26f05c141d075eb30b01c0133 356 Pfam PF02779 Transketolase, pyrimidine binding domain 18 191 2.0E-42 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain MB46_14365 4536f8c26f05c141d075eb30b01c0133 356 Gene3D G3DSA:3.40.50.920 220 352 1.1E-42 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 MB46_14365 4536f8c26f05c141d075eb30b01c0133 356 SMART SM00861 18 193 1.6E-61 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain MB46_14365 4536f8c26f05c141d075eb30b01c0133 356 SUPERFAMILY SSF52922 221 350 1.2E-36 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 MB46_14365 4536f8c26f05c141d075eb30b01c0133 356 Gene3D G3DSA:3.40.50.970 15 212 1.8E-73 T 14-10-2018 MB46_14365 4536f8c26f05c141d075eb30b01c0133 356 SUPERFAMILY SSF52518 18 196 3.49E-65 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold MB46_13140 2d51af2626014f97095bb9e1a807b010 178 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 22 158 9.2E-27 T 14-10-2018 IPR006464 N-acetyltransferase RimI/Ard1 GO:0006474|GO:0016407 MB46_13140 2d51af2626014f97095bb9e1a807b010 178 SUPERFAMILY SSF55729 12 162 1.2E-29 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase MB46_13140 2d51af2626014f97095bb9e1a807b010 178 Gene3D G3DSA:3.40.630.30 11 174 1.5E-35 T 14-10-2018 MB46_13140 2d51af2626014f97095bb9e1a807b010 178 Pfam PF00583 Acetyltransferase (GNAT) family 45 139 9.3E-14 T 14-10-2018 IPR000182 GNAT domain MB46_14115 a0bc55eccaea694e3738fbedd2d9acaf 472 SUPERFAMILY SSF51971 9 333 6.36E-58 T 14-10-2018 MB46_14115 a0bc55eccaea694e3738fbedd2d9acaf 472 PRINTS PR00419 Adrenodoxin reductase family signature 11 33 8.7E-17 T 14-10-2018 MB46_14115 a0bc55eccaea694e3738fbedd2d9acaf 472 PRINTS PR00419 Adrenodoxin reductase family signature 156 170 8.7E-17 T 14-10-2018 MB46_14115 a0bc55eccaea694e3738fbedd2d9acaf 472 PRINTS PR00419 Adrenodoxin reductase family signature 85 95 8.7E-17 T 14-10-2018 MB46_14115 a0bc55eccaea694e3738fbedd2d9acaf 472 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 10 179 4.8E-12 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MB46_14115 a0bc55eccaea694e3738fbedd2d9acaf 472 Gene3D G3DSA:3.40.50.720 12 467 1.4E-137 T 14-10-2018 MB46_14115 a0bc55eccaea694e3738fbedd2d9acaf 472 Gene3D G3DSA:3.50.50.60 54 333 1.4E-137 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_14115 a0bc55eccaea694e3738fbedd2d9acaf 472 PIRSF PIRSF000362 4 472 6.6E-158 T 14-10-2018 IPR021163 Ferredoxin-NADP+ reductase, adrenodoxin-type GO:0016491|GO:0055114 Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 MB46_08050 86d9530c2bbc6c8e5dd97b88a518338f 460 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 44 54 - T 14-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 MB46_08050 86d9530c2bbc6c8e5dd97b88a518338f 460 SUPERFAMILY SSF51905 8 330 7.58E-57 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_08050 86d9530c2bbc6c8e5dd97b88a518338f 460 PIRSF PIRSF000350 1 454 2.6E-70 T 14-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 MB46_08050 86d9530c2bbc6c8e5dd97b88a518338f 460 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 341 449 9.4E-23 T 14-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 MB46_08050 86d9530c2bbc6c8e5dd97b88a518338f 460 SUPERFAMILY SSF55424 340 459 5.5E-30 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 MB46_08050 86d9530c2bbc6c8e5dd97b88a518338f 460 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 9 459 8.4E-133 T 14-10-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 MB46_08050 86d9530c2bbc6c8e5dd97b88a518338f 460 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 12 31 1.4E-34 T 14-10-2018 MB46_08050 86d9530c2bbc6c8e5dd97b88a518338f 460 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 136 154 1.4E-34 T 14-10-2018 MB46_08050 86d9530c2bbc6c8e5dd97b88a518338f 460 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 258 274 1.4E-34 T 14-10-2018 MB46_08050 86d9530c2bbc6c8e5dd97b88a518338f 460 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 286 308 1.4E-34 T 14-10-2018 MB46_08050 86d9530c2bbc6c8e5dd97b88a518338f 460 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 174 192 1.4E-34 T 14-10-2018 MB46_08050 86d9530c2bbc6c8e5dd97b88a518338f 460 Gene3D G3DSA:3.50.50.60 10 326 6.6E-103 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_08050 86d9530c2bbc6c8e5dd97b88a518338f 460 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 174 199 3.0E-63 T 14-10-2018 MB46_08050 86d9530c2bbc6c8e5dd97b88a518338f 460 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 301 308 3.0E-63 T 14-10-2018 MB46_08050 86d9530c2bbc6c8e5dd97b88a518338f 460 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 43 58 3.0E-63 T 14-10-2018 MB46_08050 86d9530c2bbc6c8e5dd97b88a518338f 460 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 402 417 3.0E-63 T 14-10-2018 MB46_08050 86d9530c2bbc6c8e5dd97b88a518338f 460 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 139 148 3.0E-63 T 14-10-2018 MB46_08050 86d9530c2bbc6c8e5dd97b88a518338f 460 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 424 444 3.0E-63 T 14-10-2018 MB46_08050 86d9530c2bbc6c8e5dd97b88a518338f 460 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 11 33 3.0E-63 T 14-10-2018 MB46_08050 86d9530c2bbc6c8e5dd97b88a518338f 460 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 337 358 3.0E-63 T 14-10-2018 MB46_08050 86d9530c2bbc6c8e5dd97b88a518338f 460 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 259 273 3.0E-63 T 14-10-2018 MB46_08050 86d9530c2bbc6c8e5dd97b88a518338f 460 Gene3D G3DSA:3.30.390.30 340 459 6.8E-33 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 MB46_08050 86d9530c2bbc6c8e5dd97b88a518338f 460 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 10 321 8.3E-63 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MB46_08050 86d9530c2bbc6c8e5dd97b88a518338f 460 Gene3D G3DSA:3.50.50.60 148 265 6.6E-103 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_06320 73747eedb7819b4cb9d07c9010b52a72 561 ProSitePatterns PS00211 ABC transporters family signature. 447 461 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_06320 73747eedb7819b4cb9d07c9010b52a72 561 Pfam PF00005 ABC transporter 26 181 1.2E-26 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_06320 73747eedb7819b4cb9d07c9010b52a72 561 SMART SM00382 330 524 4.9E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_06320 73747eedb7819b4cb9d07c9010b52a72 561 SMART SM00382 34 231 2.1E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_06320 73747eedb7819b4cb9d07c9010b52a72 561 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 233 263 0.0055 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MB46_06320 73747eedb7819b4cb9d07c9010b52a72 561 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 526 557 0.021 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MB46_06320 73747eedb7819b4cb9d07c9010b52a72 561 SUPERFAMILY SSF52540 4 252 9.76E-60 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_06320 73747eedb7819b4cb9d07c9010b52a72 561 Pfam PF00005 ABC transporter 321 474 9.7E-33 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_06320 73747eedb7819b4cb9d07c9010b52a72 561 SUPERFAMILY SSF52540 299 545 9.37E-66 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_06320 73747eedb7819b4cb9d07c9010b52a72 561 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_06320 73747eedb7819b4cb9d07c9010b52a72 561 Gene3D G3DSA:3.40.50.300 298 560 5.9E-77 T 14-10-2018 MB46_06320 73747eedb7819b4cb9d07c9010b52a72 561 Gene3D G3DSA:3.40.50.300 2 297 6.0E-77 T 14-10-2018 MB46_01480 4e23ee9d15c3d573c8bc905a154546ed 302 Gene3D G3DSA:3.40.50.150 21 302 6.9E-72 T 14-10-2018 MB46_01480 4e23ee9d15c3d573c8bc905a154546ed 302 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 46 52 - T 14-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 MB46_01480 4e23ee9d15c3d573c8bc905a154546ed 302 Pfam PF01555 DNA methylase 44 282 5.3E-46 T 14-10-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 MB46_01480 4e23ee9d15c3d573c8bc905a154546ed 302 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 42 56 2.6E-24 T 14-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 MB46_01480 4e23ee9d15c3d573c8bc905a154546ed 302 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 227 244 2.6E-24 T 14-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 MB46_01480 4e23ee9d15c3d573c8bc905a154546ed 302 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 269 289 2.6E-24 T 14-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 MB46_01480 4e23ee9d15c3d573c8bc905a154546ed 302 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 246 264 2.6E-24 T 14-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 MB46_01480 4e23ee9d15c3d573c8bc905a154546ed 302 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 105 125 2.6E-24 T 14-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 MB46_01480 4e23ee9d15c3d573c8bc905a154546ed 302 SUPERFAMILY SSF53335 21 289 1.19E-65 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MB46_02785 a735e7ff1c970d65e38dae3b45e1789e 469 ProSitePatterns PS00216 Sugar transport proteins signature 1. 332 349 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MB46_02785 a735e7ff1c970d65e38dae3b45e1789e 469 ProSitePatterns PS00217 Sugar transport proteins signature 2. 134 159 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MB46_02785 a735e7ff1c970d65e38dae3b45e1789e 469 Gene3D G3DSA:1.20.1250.20 18 467 1.4E-60 T 14-10-2018 MB46_02785 a735e7ff1c970d65e38dae3b45e1789e 469 Pfam PF00083 Sugar (and other) transporter 22 226 5.5E-24 T 14-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 MB46_02785 a735e7ff1c970d65e38dae3b45e1789e 469 Pfam PF00083 Sugar (and other) transporter 308 460 9.8E-12 T 14-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 MB46_02785 a735e7ff1c970d65e38dae3b45e1789e 469 SUPERFAMILY SSF103473 10 462 3.14E-58 T 14-10-2018 IPR036259 MFS transporter superfamily MB46_11010 996aa5eb45f075cfed5919b41fd33916 1321 Pfam PF00271 Helicase conserved C-terminal domain 243 366 2.2E-9 T 14-10-2018 IPR001650 Helicase, C-terminal MB46_11010 996aa5eb45f075cfed5919b41fd33916 1321 Gene3D G3DSA:1.20.120.1080 413 512 5.9E-16 T 14-10-2018 MB46_11010 996aa5eb45f075cfed5919b41fd33916 1321 Gene3D G3DSA:3.40.50.300 5 190 2.5E-75 T 14-10-2018 MB46_11010 996aa5eb45f075cfed5919b41fd33916 1321 SMART SM00490 266 367 5.9E-11 T 14-10-2018 IPR001650 Helicase, C-terminal MB46_11010 996aa5eb45f075cfed5919b41fd33916 1321 SMART SM00847 431 521 1.6E-31 T 14-10-2018 IPR007502 Helicase-associated domain GO:0004386 MB46_11010 996aa5eb45f075cfed5919b41fd33916 1321 SUPERFAMILY SSF52540 8 529 7.1E-101 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_11010 996aa5eb45f075cfed5919b41fd33916 1321 SMART SM00487 9 197 6.4E-25 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MB46_11010 996aa5eb45f075cfed5919b41fd33916 1321 ProSitePatterns PS00690 DEAH-box subfamily ATP-dependent helicases signature. 126 135 - T 14-10-2018 IPR002464 DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site MB46_11010 996aa5eb45f075cfed5919b41fd33916 1321 Pfam PF04408 Helicase associated domain (HA2) 434 512 2.4E-16 T 14-10-2018 IPR007502 Helicase-associated domain GO:0004386 MB46_11010 996aa5eb45f075cfed5919b41fd33916 1321 TIGRFAM TIGR01967 DEAH_box_HrpA: RNA helicase HrpA 4 981 0.0 T 14-10-2018 IPR010222 RNA helicase HrpA GO:0004004 MB46_11010 996aa5eb45f075cfed5919b41fd33916 1321 SMART SM00382 26 347 5.8E-5 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_11010 996aa5eb45f075cfed5919b41fd33916 1321 Pfam PF07717 Oligonucleotide/oligosaccharide-binding (OB)-fold 588 664 2.4E-18 T 14-10-2018 IPR011709 Domain of unknown function DUF1605 MB46_11010 996aa5eb45f075cfed5919b41fd33916 1321 Gene3D G3DSA:3.40.50.300 191 385 2.6E-53 T 14-10-2018 MB46_11010 996aa5eb45f075cfed5919b41fd33916 1321 Pfam PF00270 DEAD/DEAH box helicase 20 167 1.5E-5 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MB46_11010 996aa5eb45f075cfed5919b41fd33916 1321 Pfam PF11898 Domain of unknown function (DUF3418) 678 1317 9.4E-218 T 14-10-2018 IPR024590 RNA helicase HrpA, C-terminal MB46_08450 f16b7d1818440dfdc828bce35afbf1b0 452 Pfam PF02441 Flavoprotein 2 168 1.4E-34 T 14-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 MB46_08450 f16b7d1818440dfdc828bce35afbf1b0 452 SUPERFAMILY SSF102645 220 449 1.83E-64 T 14-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 MB46_08450 f16b7d1818440dfdc828bce35afbf1b0 452 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 224 419 9.7E-64 T 14-10-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 MB46_08450 f16b7d1818440dfdc828bce35afbf1b0 452 SUPERFAMILY SSF52507 2 171 7.59E-51 T 14-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 MB46_08450 f16b7d1818440dfdc828bce35afbf1b0 452 Gene3D G3DSA:3.40.50.10300 216 451 1.5E-77 T 14-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 MB46_08450 f16b7d1818440dfdc828bce35afbf1b0 452 Gene3D G3DSA:3.40.50.1950 1 181 7.8E-45 T 14-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 MB46_13325 989eb5cb3daef65ec66972dd6ea4f1d4 253 SUPERFAMILY SSF51695 2 244 6.8E-62 T 14-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 MB46_13325 989eb5cb3daef65ec66972dd6ea4f1d4 253 Gene3D G3DSA:3.20.20.190 1 247 5.3E-63 T 14-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 MB46_13325 989eb5cb3daef65ec66972dd6ea4f1d4 253 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 6 238 8.8E-34 T 14-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 MB46_01320 409dd55ad7a7ac7cb336248852f6b69d 245 Gene3D G3DSA:1.10.357.10 24 240 3.3E-19 T 14-10-2018 MB46_01320 409dd55ad7a7ac7cb336248852f6b69d 245 SUPERFAMILY SSF46689 32 101 1.33E-11 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MB46_01320 409dd55ad7a7ac7cb336248852f6b69d 245 Pfam PF00440 Bacterial regulatory proteins, tetR family 42 86 2.5E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MB46_10510 52d997d01791c7093a8e51473521909f 150 SMART SM00347 30 133 1.2E-12 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MB46_10510 52d997d01791c7093a8e51473521909f 150 Gene3D G3DSA:1.10.10.10 7 148 2.0E-26 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_10510 52d997d01791c7093a8e51473521909f 150 ProSitePatterns PS01117 MarR-type HTH domain signature. 71 105 - T 14-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site MB46_10510 52d997d01791c7093a8e51473521909f 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 56 72 3.8E-13 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MB46_10510 52d997d01791c7093a8e51473521909f 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 73 88 3.8E-13 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MB46_10510 52d997d01791c7093a8e51473521909f 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 123 143 3.8E-13 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MB46_10510 52d997d01791c7093a8e51473521909f 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 92 108 3.8E-13 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MB46_10510 52d997d01791c7093a8e51473521909f 150 SUPERFAMILY SSF46785 20 146 1.09E-24 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_10510 52d997d01791c7093a8e51473521909f 150 Pfam PF12802 MarR family 40 96 8.4E-12 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MB46_16115 c14a24655aa805c161306c4a0eb33bd1 410 TIGRFAM TIGR00611 recf: DNA replication and repair protein RecF 1 398 2.6E-109 T 14-10-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 MB46_16115 c14a24655aa805c161306c4a0eb33bd1 410 Gene3D G3DSA:1.20.1050.90 120 351 3.4E-90 T 14-10-2018 MB46_16115 c14a24655aa805c161306c4a0eb33bd1 410 Hamap MF_00365 DNA replication and repair protein RecF [recF]. 1 410 85.708 T 14-10-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 MB46_16115 c14a24655aa805c161306c4a0eb33bd1 410 ProSitePatterns PS00618 RecF protein signature 2. 352 370 - T 14-10-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 MB46_16115 c14a24655aa805c161306c4a0eb33bd1 410 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 384 3.0E-19 T 14-10-2018 IPR003395 RecF/RecN/SMC, N-terminal MB46_16115 c14a24655aa805c161306c4a0eb33bd1 410 ProSitePatterns PS00617 RecF protein signature 1. 117 137 - T 14-10-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 MB46_16115 c14a24655aa805c161306c4a0eb33bd1 410 SUPERFAMILY SSF52540 1 376 7.93E-42 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_16115 c14a24655aa805c161306c4a0eb33bd1 410 Gene3D G3DSA:3.40.50.300 6 384 3.4E-90 T 14-10-2018 MB46_01260 d6e36d0d333318ddd94cdd64347cbb5e 473 PRINTS PR00149 Fumarate lyase superfamily signature 189 207 6.9E-29 T 14-10-2018 IPR000362 Fumarate lyase family MB46_01260 d6e36d0d333318ddd94cdd64347cbb5e 473 PRINTS PR00149 Fumarate lyase superfamily signature 280 307 6.9E-29 T 14-10-2018 IPR000362 Fumarate lyase family MB46_01260 d6e36d0d333318ddd94cdd64347cbb5e 473 PRINTS PR00149 Fumarate lyase superfamily signature 326 342 6.9E-29 T 14-10-2018 IPR000362 Fumarate lyase family MB46_01260 d6e36d0d333318ddd94cdd64347cbb5e 473 PRINTS PR00149 Fumarate lyase superfamily signature 144 162 6.9E-29 T 14-10-2018 IPR000362 Fumarate lyase family MB46_01260 d6e36d0d333318ddd94cdd64347cbb5e 473 Gene3D G3DSA:1.10.275.10 10 148 6.0E-59 T 14-10-2018 IPR024083 Fumarase/histidase, N-terminal MB46_01260 d6e36d0d333318ddd94cdd64347cbb5e 473 Gene3D G3DSA:1.10.40.30 417 468 1.1E-18 T 14-10-2018 MB46_01260 d6e36d0d333318ddd94cdd64347cbb5e 473 ProSitePatterns PS00163 Fumarate lyases signature. 326 335 - T 14-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 MB46_01260 d6e36d0d333318ddd94cdd64347cbb5e 473 Pfam PF00206 Lyase 22 351 2.2E-95 T 14-10-2018 IPR022761 Fumarate lyase, N-terminal MB46_01260 d6e36d0d333318ddd94cdd64347cbb5e 473 Pfam PF10415 Fumarase C C-terminus 417 469 7.2E-18 T 14-10-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 MB46_01260 d6e36d0d333318ddd94cdd64347cbb5e 473 SUPERFAMILY SSF48557 12 468 2.06E-144 T 14-10-2018 IPR008948 L-Aspartase-like GO:0003824 MB46_01260 d6e36d0d333318ddd94cdd64347cbb5e 473 TIGRFAM TIGR00839 aspA: aspartate ammonia-lyase 13 470 3.6E-206 T 14-10-2018 IPR004708 Aspartate ammonia-lyase GO:0006531|GO:0008797 KEGG: 00250+4.3.1.1 MB46_01260 d6e36d0d333318ddd94cdd64347cbb5e 473 Gene3D G3DSA:1.20.200.10 149 416 8.5E-108 T 14-10-2018 MB46_11990 1e62c74fb380c4e3581e40e2a576a188 1088 Gene3D G3DSA:3.40.50.300 383 481 5.0E-7 T 14-10-2018 MB46_11990 1e62c74fb380c4e3581e40e2a576a188 1088 Pfam PF13245 AAA domain 23 278 3.2E-10 T 14-10-2018 MB46_11990 1e62c74fb380c4e3581e40e2a576a188 1088 Pfam PF12705 PD-(D/E)XK nuclease superfamily 825 1078 3.6E-27 T 14-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type MB46_11990 1e62c74fb380c4e3581e40e2a576a188 1088 Gene3D G3DSA:3.40.50.300 581 743 8.5E-14 T 14-10-2018 MB46_11990 1e62c74fb380c4e3581e40e2a576a188 1088 Pfam PF13361 UvrD-like helicase C-terminal domain 582 722 3.5E-6 T 14-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 MB46_11990 1e62c74fb380c4e3581e40e2a576a188 1088 Gene3D G3DSA:3.40.50.300 20 302 1.0E-30 T 14-10-2018 MB46_11990 1e62c74fb380c4e3581e40e2a576a188 1088 SUPERFAMILY SSF52540 18 735 3.39E-62 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_11990 1e62c74fb380c4e3581e40e2a576a188 1088 Gene3D G3DSA:1.10.10.160 125 224 1.0E-30 T 14-10-2018 IPR013986 DExx box DNA helicase domain superfamily MB46_04255 3ad93350bd6a3973646dc5888b06aa2e 274 SMART SM00363 2 68 9.5E-7 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MB46_04255 3ad93350bd6a3973646dc5888b06aa2e 274 SUPERFAMILY SSF53335 56 194 3.32E-18 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MB46_04255 3ad93350bd6a3973646dc5888b06aa2e 274 Gene3D G3DSA:3.10.290.10 1 61 1.2E-15 T 14-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 MB46_04255 3ad93350bd6a3973646dc5888b06aa2e 274 SUPERFAMILY SSF55174 3 59 7.07E-9 T 14-10-2018 MB46_04255 3ad93350bd6a3973646dc5888b06aa2e 274 TIGRFAM TIGR00478 tly: TlyA family rRNA methyltransferase/putative hemolysin 3 236 2.4E-58 T 14-10-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 MB46_04255 3ad93350bd6a3973646dc5888b06aa2e 274 PIRSF PIRSF005578 1 260 4.1E-84 T 14-10-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 MB46_04255 3ad93350bd6a3973646dc5888b06aa2e 274 Pfam PF01479 S4 domain 3 46 6.1E-8 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MB46_04255 3ad93350bd6a3973646dc5888b06aa2e 274 Pfam PF01728 FtsJ-like methyltransferase 59 237 1.6E-17 T 14-10-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 MB46_04255 3ad93350bd6a3973646dc5888b06aa2e 274 Gene3D G3DSA:3.40.50.150 62 266 2.2E-66 T 14-10-2018 MB46_11930 a11a8c81bf337b7987946b0aff976a77 125 Pfam PF09851 Short C-terminal domain 97 124 4.2E-7 T 14-10-2018 IPR018649 SHOCT domain MB46_02855 c4273aaaebea92efc1d0e55ca41e8275 779 TIGRFAM TIGR02965 xanthine_xdhB: xanthine dehydrogenase, molybdopterin binding subunit 14 772 4.5E-269 T 14-10-2018 IPR014309 Xanthine dehydrogenase, molybdopterin binding subunit GO:0030151 KEGG: 00230+1.17.1.4+1.17.3.2|KEGG: 00232+1.17.3.2|KEGG: 00983+1.17.3.2|MetaCyc: PWY-5497|MetaCyc: PWY-5695|MetaCyc: PWY-6538|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-6999 MB46_02855 c4273aaaebea92efc1d0e55ca41e8275 779 Gene3D G3DSA:3.30.365.10 181 275 4.9E-263 T 14-10-2018 MB46_02855 c4273aaaebea92efc1d0e55ca41e8275 779 Gene3D G3DSA:3.30.365.10 134 766 4.9E-263 T 14-10-2018 MB46_02855 c4273aaaebea92efc1d0e55ca41e8275 779 Gene3D G3DSA:3.30.365.10 451 600 4.9E-263 T 14-10-2018 MB46_02855 c4273aaaebea92efc1d0e55ca41e8275 779 SMART SM01008 27 133 2.0E-36 T 14-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead MB46_02855 c4273aaaebea92efc1d0e55ca41e8275 779 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 154 703 2.8E-190 T 14-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 MB46_02855 c4273aaaebea92efc1d0e55ca41e8275 779 SUPERFAMILY SSF54665 7 133 4.71E-36 T 14-10-2018 IPR036856 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily MB46_02855 c4273aaaebea92efc1d0e55ca41e8275 779 Gene3D G3DSA:3.90.1170.50 13 133 4.9E-263 T 14-10-2018 MB46_02855 c4273aaaebea92efc1d0e55ca41e8275 779 SUPERFAMILY SSF56003 133 772 2.22E-187 T 14-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 MB46_02855 c4273aaaebea92efc1d0e55ca41e8275 779 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 27 133 1.4E-21 T 14-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead MB46_02855 c4273aaaebea92efc1d0e55ca41e8275 779 Gene3D G3DSA:3.30.365.10 147 398 4.9E-263 T 14-10-2018 MB46_17215 01e7579477ba85dadc9a8193b359e6f4 229 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 8 227 1.7E-55 T 14-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 MB46_17215 01e7579477ba85dadc9a8193b359e6f4 229 SUPERFAMILY SSF53335 6 214 4.03E-37 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MB46_17215 01e7579477ba85dadc9a8193b359e6f4 229 Pfam PF01209 ubiE/COQ5 methyltransferase family 4 222 3.0E-47 T 14-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 MB46_17215 01e7579477ba85dadc9a8193b359e6f4 229 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 2 227 28.489 T 14-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 MB46_17215 01e7579477ba85dadc9a8193b359e6f4 229 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 136 150 - T 14-10-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 MB46_17215 01e7579477ba85dadc9a8193b359e6f4 229 Gene3D G3DSA:3.40.50.150 14 228 2.9E-51 T 14-10-2018 MB46_04520 efb13053640877bf335748ce985a4769 363 Pfam PF00534 Glycosyl transferases group 1 193 325 9.3E-14 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 MB46_04520 efb13053640877bf335748ce985a4769 363 SUPERFAMILY SSF53756 26 361 1.47E-43 T 14-10-2018 MB46_04520 efb13053640877bf335748ce985a4769 363 Gene3D G3DSA:3.40.50.2000 179 342 9.2E-31 T 14-10-2018 MB46_04520 efb13053640877bf335748ce985a4769 363 Pfam PF13439 Glycosyltransferase Family 4 76 177 7.4E-7 T 14-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 MB46_04520 efb13053640877bf335748ce985a4769 363 Gene3D G3DSA:3.40.50.2000 101 356 9.2E-31 T 14-10-2018 MB46_17425 013958d2db51656eedb3930f1f2f2a51 781 Pfam PF00271 Helicase conserved C-terminal domain 296 406 8.3E-11 T 14-10-2018 IPR001650 Helicase, C-terminal MB46_17425 013958d2db51656eedb3930f1f2f2a51 781 Gene3D G3DSA:3.40.50.300 279 437 5.6E-20 T 14-10-2018 MB46_17425 013958d2db51656eedb3930f1f2f2a51 781 Pfam PF00270 DEAD/DEAH box helicase 60 237 1.5E-17 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MB46_17425 013958d2db51656eedb3930f1f2f2a51 781 Pfam PF09369 Domain of unknown function (DUF1998) 667 746 8.2E-21 T 14-10-2018 IPR018973 DEAD/DEAH-box helicase, putative MB46_17425 013958d2db51656eedb3930f1f2f2a51 781 SMART SM00490 328 406 5.7E-14 T 14-10-2018 IPR001650 Helicase, C-terminal MB46_17425 013958d2db51656eedb3930f1f2f2a51 781 SMART SM00487 52 266 5.5E-21 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MB46_17425 013958d2db51656eedb3930f1f2f2a51 781 Gene3D G3DSA:3.40.50.300 38 256 2.7E-34 T 14-10-2018 MB46_17425 013958d2db51656eedb3930f1f2f2a51 781 TIGRFAM TIGR03817 DECH_helic: helicase/secretion neighborhood putative DEAH-box helicase 20 773 0.0 T 14-10-2018 IPR022307 DEAD/DEAH-box helicase, putative, actinobacteria MB46_17425 013958d2db51656eedb3930f1f2f2a51 781 SUPERFAMILY SSF52540 69 417 1.05E-37 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_15485 e9852a824af9195bc43ca80c9c98844c 212 Gene3D G3DSA:1.10.286.10 21 76 3.9E-22 T 14-10-2018 MB46_15485 e9852a824af9195bc43ca80c9c98844c 212 ProSitePatterns PS00859 GTP cyclohydrolase I signature 1. 88 104 - T 14-10-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 MB46_15485 e9852a824af9195bc43ca80c9c98844c 212 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 28 210 41.24 T 14-10-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 MB46_15485 e9852a824af9195bc43ca80c9c98844c 212 SUPERFAMILY SSF55620 22 209 1.85E-75 T 14-10-2018 MB46_15485 e9852a824af9195bc43ca80c9c98844c 212 ProSitePatterns PS00860 GTP cyclohydrolase I signature 2. 138 148 - T 14-10-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 MB46_15485 e9852a824af9195bc43ca80c9c98844c 212 Pfam PF01227 GTP cyclohydrolase I 32 209 2.6E-76 T 14-10-2018 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 MB46_15485 e9852a824af9195bc43ca80c9c98844c 212 Gene3D G3DSA:3.30.1130.10 79 210 5.0E-57 T 14-10-2018 MB46_15485 e9852a824af9195bc43ca80c9c98844c 212 TIGRFAM TIGR00063 folE: GTP cyclohydrolase I 32 209 1.8E-71 T 14-10-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 MB46_19910 46f062a639bd282d4258a50cf2d8128b 97 Pfam PF00462 Glutaredoxin 4 62 9.6E-11 T 14-10-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 MB46_19910 46f062a639bd282d4258a50cf2d8128b 97 Gene3D G3DSA:3.40.30.10 3 81 4.7E-23 T 14-10-2018 MB46_19910 46f062a639bd282d4258a50cf2d8128b 97 SUPERFAMILY SSF52833 4 71 3.96E-15 T 14-10-2018 IPR036249 Thioredoxin-like superfamily MB46_14605 35fca6d3e9e7674276ba21b02753edde 108 Pfam PF14012 Protein of unknown function (DUF4229) 5 63 6.4E-10 T 14-10-2018 IPR025323 Protein of unknown function DUF4229 MB46_17400 a4004ad3b73d0d7c84e47adafa0e5556 436 Pfam PF00437 Type II/IV secretion system protein 75 347 9.4E-63 T 14-10-2018 IPR001482 Type II/IV secretion system protein MB46_17400 a4004ad3b73d0d7c84e47adafa0e5556 436 SUPERFAMILY SSF52540 63 360 3.52E-45 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_17400 a4004ad3b73d0d7c84e47adafa0e5556 436 TIGRFAM TIGR03819 heli_sec_ATPase: helicase/secretion neighborhood ATPase 24 360 1.2E-135 T 14-10-2018 IPR022399 Helicase/secretion neighbourhood ATPase MB46_17400 a4004ad3b73d0d7c84e47adafa0e5556 436 Gene3D G3DSA:3.30.450.90 70 172 8.0E-23 T 14-10-2018 MB46_17400 a4004ad3b73d0d7c84e47adafa0e5556 436 Gene3D G3DSA:3.40.50.300 173 369 1.1E-49 T 14-10-2018 MB46_03495 6a7cb852b15fcb5bdb068adb0b15d8e0 275 SUPERFAMILY SSF54713 57 274 2.86E-41 T 14-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 MB46_03495 6a7cb852b15fcb5bdb068adb0b15d8e0 275 ProSitePatterns PS01126 Elongation factor Ts signature 1. 12 27 - T 14-10-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MB46_03495 6a7cb852b15fcb5bdb068adb0b15d8e0 275 SUPERFAMILY SSF46934 5 55 6.43E-15 T 14-10-2018 IPR009060 UBA-like superfamily GO:0005515 MB46_03495 6a7cb852b15fcb5bdb068adb0b15d8e0 275 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 1 274 3.9E-79 T 14-10-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MB46_03495 6a7cb852b15fcb5bdb068adb0b15d8e0 275 Gene3D G3DSA:1.10.8.10 1 55 1.5E-21 T 14-10-2018 MB46_03495 6a7cb852b15fcb5bdb068adb0b15d8e0 275 Gene3D G3DSA:3.30.479.20 162 274 1.9E-36 T 14-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 MB46_03495 6a7cb852b15fcb5bdb068adb0b15d8e0 275 Gene3D G3DSA:1.10.286.20 194 240 1.9E-36 T 14-10-2018 MB46_03495 6a7cb852b15fcb5bdb068adb0b15d8e0 275 Hamap MF_00050 Elongation factor Ts [tsf]. 1 275 63.303 T 14-10-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MB46_03495 6a7cb852b15fcb5bdb068adb0b15d8e0 275 Gene3D G3DSA:3.30.479.20 57 147 1.3E-21 T 14-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 MB46_03495 6a7cb852b15fcb5bdb068adb0b15d8e0 275 Pfam PF00889 Elongation factor TS 71 274 2.2E-60 T 14-10-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0006414 Reactome: R-HSA-5389840 MB46_13475 0b9fd2bca7d269c9fa364768c1b80c7b 1300 Pfam PF04997 RNA polymerase Rpb1, domain 1 9 417 9.8E-79 T 14-10-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MB46_13475 0b9fd2bca7d269c9fa364768c1b80c7b 1300 Pfam PF04998 RNA polymerase Rpb1, domain 5 829 1195 5.9E-60 T 14-10-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MB46_13475 0b9fd2bca7d269c9fa364768c1b80c7b 1300 Pfam PF00623 RNA polymerase Rpb1, domain 2 482 560 1.9E-27 T 14-10-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MB46_13475 0b9fd2bca7d269c9fa364768c1b80c7b 1300 Pfam PF00623 RNA polymerase Rpb1, domain 2 419 462 2.7E-8 T 14-10-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MB46_13475 0b9fd2bca7d269c9fa364768c1b80c7b 1300 Gene3D G3DSA:1.10.274.100 565 718 9.9E-37 T 14-10-2018 MB46_13475 0b9fd2bca7d269c9fa364768c1b80c7b 1300 Gene3D G3DSA:1.10.40.90 449 491 6.5E-23 T 14-10-2018 MB46_13475 0b9fd2bca7d269c9fa364768c1b80c7b 1300 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 10 1246 0.0 T 14-10-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MB46_13475 0b9fd2bca7d269c9fa364768c1b80c7b 1300 Gene3D G3DSA:1.10.150.390 1196 1259 4.5E-28 T 14-10-2018 MB46_13475 0b9fd2bca7d269c9fa364768c1b80c7b 1300 Gene3D G3DSA:1.10.1790.20 1016 1194 1.6E-65 T 14-10-2018 MB46_13475 0b9fd2bca7d269c9fa364768c1b80c7b 1300 Gene3D G3DSA:1.10.132.30 719 853 2.8E-51 T 14-10-2018 IPR038120 RNA polymerase Rpb1, funnel domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MB46_13475 0b9fd2bca7d269c9fa364768c1b80c7b 1300 Pfam PF05000 RNA polymerase Rpb1, domain 4 758 817 7.6E-10 T 14-10-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MB46_13475 0b9fd2bca7d269c9fa364768c1b80c7b 1300 Pfam PF04983 RNA polymerase Rpb1, domain 3 564 722 6.8E-22 T 14-10-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MB46_13475 0b9fd2bca7d269c9fa364768c1b80c7b 1300 Gene3D G3DSA:2.40.50.100 1032 1095 1.6E-65 T 14-10-2018 MB46_13475 0b9fd2bca7d269c9fa364768c1b80c7b 1300 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 1 1257 17.508 T 14-10-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MB46_13475 0b9fd2bca7d269c9fa364768c1b80c7b 1300 SMART SM00663 310 589 7.0E-174 T 14-10-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MB46_13475 0b9fd2bca7d269c9fa364768c1b80c7b 1300 SUPERFAMILY SSF64484 9 1247 0.0 T 14-10-2018 MB46_07845 1f08dc1beda84f9dca9285f081793224 407 PIRSF PIRSF000429 4 397 2.0E-118 T 14-10-2018 IPR002155 Thiolase GO:0016747 MB46_07845 1f08dc1beda84f9dca9285f081793224 407 Pfam PF00108 Thiolase, N-terminal domain 10 262 1.3E-54 T 14-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 MB46_07845 1f08dc1beda84f9dca9285f081793224 407 Gene3D G3DSA:3.40.47.10 10 276 1.8E-117 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 MB46_07845 1f08dc1beda84f9dca9285f081793224 407 SUPERFAMILY SSF53901 7 268 3.3E-57 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 MB46_07845 1f08dc1beda84f9dca9285f081793224 407 Gene3D G3DSA:3.40.47.10 139 389 1.8E-117 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 MB46_07845 1f08dc1beda84f9dca9285f081793224 407 SUPERFAMILY SSF53901 274 394 9.74E-37 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 MB46_07845 1f08dc1beda84f9dca9285f081793224 407 Pfam PF02803 Thiolase, C-terminal domain 272 394 2.1E-35 T 14-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 MB46_07845 1f08dc1beda84f9dca9285f081793224 407 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 13 394 5.3E-123 T 14-10-2018 IPR002155 Thiolase GO:0016747 MB46_07845 1f08dc1beda84f9dca9285f081793224 407 ProSitePatterns PS00737 Thiolases signature 2. 341 357 - T 14-10-2018 IPR020613 Thiolase, conserved site GO:0016747 MB46_01900 59ac40096ac6a396133a10a0fa7ff2c6 185 Gene3D G3DSA:3.90.1140.10 18 181 2.3E-30 T 14-10-2018 MB46_01900 59ac40096ac6a396133a10a0fa7ff2c6 185 Pfam PF13563 2'-5' RNA ligase superfamily 25 168 1.4E-23 T 14-10-2018 MB46_01900 59ac40096ac6a396133a10a0fa7ff2c6 185 SUPERFAMILY SSF55144 18 172 8.89E-25 T 14-10-2018 IPR009097 Cyclic phosphodiesterase MB46_05625 38cfd31f41ac6e06c31d279eb75fb2d4 279 Gene3D G3DSA:2.40.128.110 118 279 4.2E-25 T 14-10-2018 IPR036761 Lipid/polyisoprenoid-binding, YceI-like superfamily MB46_05625 38cfd31f41ac6e06c31d279eb75fb2d4 279 Pfam PF04264 YceI-like domain 121 275 1.1E-18 T 14-10-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like MB46_05625 38cfd31f41ac6e06c31d279eb75fb2d4 279 SUPERFAMILY SSF101874 116 277 1.44E-22 T 14-10-2018 IPR036761 Lipid/polyisoprenoid-binding, YceI-like superfamily MB46_05625 38cfd31f41ac6e06c31d279eb75fb2d4 279 SMART SM00867 115 278 9.4E-14 T 14-10-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like MB46_10850 b92669b79d26fa16b0bfbf2edb6b7501 545 Gene3D G3DSA:2.40.30.20 4 97 4.2E-24 T 14-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 MB46_10850 b92669b79d26fa16b0bfbf2edb6b7501 545 SUPERFAMILY SSF47917 385 511 4.97E-45 T 14-10-2018 MB46_10850 b92669b79d26fa16b0bfbf2edb6b7501 545 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 4 512 47.706 T 14-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MB46_10850 b92669b79d26fa16b0bfbf2edb6b7501 545 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 6 511 1.5E-236 T 14-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MB46_10850 b92669b79d26fa16b0bfbf2edb6b7501 545 SUPERFAMILY SSF50615 26 98 2.75E-22 T 14-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 MB46_10850 b92669b79d26fa16b0bfbf2edb6b7501 545 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 31 96 9.8E-12 T 14-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 MB46_10850 b92669b79d26fa16b0bfbf2edb6b7501 545 Gene3D G3DSA:1.20.150.20 384 513 7.2E-48 T 14-10-2018 IPR038376 ATP synthase, alpha subunit, C-terminal domain superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MB46_10850 b92669b79d26fa16b0bfbf2edb6b7501 545 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 367 376 - T 14-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 MB46_10850 b92669b79d26fa16b0bfbf2edb6b7501 545 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 383 507 4.5E-45 T 14-10-2018 IPR000793 ATP synthase, alpha subunit, C-terminal GO:0015986 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MB46_10850 b92669b79d26fa16b0bfbf2edb6b7501 545 SUPERFAMILY SSF52540 100 382 2.08E-94 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_10850 b92669b79d26fa16b0bfbf2edb6b7501 545 Gene3D G3DSA:3.40.50.300 98 383 2.8E-117 T 14-10-2018 MB46_10850 b92669b79d26fa16b0bfbf2edb6b7501 545 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 153 376 1.5E-66 T 14-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 MB46_10925 ade71a262a5a57c2d5e8f26c985e0ad0 357 Pfam PF00472 RF-1 domain 213 320 1.5E-36 T 14-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 MB46_10925 ade71a262a5a57c2d5e8f26c985e0ad0 357 Gene3D G3DSA:1.20.58.410 4 95 3.8E-9 T 14-10-2018 MB46_10925 ade71a262a5a57c2d5e8f26c985e0ad0 357 Gene3D G3DSA:3.30.70.1660 104 341 8.2E-91 T 14-10-2018 MB46_10925 ade71a262a5a57c2d5e8f26c985e0ad0 357 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 1 356 37.049 T 14-10-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 MB46_10925 ade71a262a5a57c2d5e8f26c985e0ad0 357 SMART SM00937 63 177 7.8E-53 T 14-10-2018 IPR005139 Peptide chain release factor GO:0006415 MB46_10925 ade71a262a5a57c2d5e8f26c985e0ad0 357 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 227 243 - T 14-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 MB46_10925 ade71a262a5a57c2d5e8f26c985e0ad0 357 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 2 354 1.9E-142 T 14-10-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 MB46_10925 ade71a262a5a57c2d5e8f26c985e0ad0 357 SUPERFAMILY SSF75620 8 352 1.57E-122 T 14-10-2018 MB46_10925 ade71a262a5a57c2d5e8f26c985e0ad0 357 Pfam PF03462 PCRF domain 10 202 1.6E-65 T 14-10-2018 IPR005139 Peptide chain release factor GO:0006415 MB46_10925 ade71a262a5a57c2d5e8f26c985e0ad0 357 Gene3D G3DSA:3.30.160.20 209 296 8.2E-91 T 14-10-2018 MB46_16570 fb1753269889ae6610cd10f58df74dbf 324 Gene3D G3DSA:3.40.50.970 1 200 1.9E-75 T 14-10-2018 MB46_16570 fb1753269889ae6610cd10f58df74dbf 324 Pfam PF02780 Transketolase, C-terminal domain 194 313 2.9E-38 T 14-10-2018 IPR033248 Transketolase, C-terminal domain MB46_16570 fb1753269889ae6610cd10f58df74dbf 324 SMART SM00861 4 179 2.1E-65 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain MB46_16570 fb1753269889ae6610cd10f58df74dbf 324 Pfam PF02779 Transketolase, pyrimidine binding domain 3 177 5.6E-42 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain MB46_16570 fb1753269889ae6610cd10f58df74dbf 324 SUPERFAMILY SSF52518 3 185 8.34E-65 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold MB46_16570 fb1753269889ae6610cd10f58df74dbf 324 Gene3D G3DSA:3.40.50.920 201 320 2.5E-42 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 MB46_16570 fb1753269889ae6610cd10f58df74dbf 324 SUPERFAMILY SSF52922 194 321 9.03E-38 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 MB46_04975 81d4bf4faff837aaf2c59c984fee319d 324 Pfam PF00248 Aldo/keto reductase family 17 300 2.5E-54 T 14-10-2018 IPR023210 NADP-dependent oxidoreductase domain MB46_04975 81d4bf4faff837aaf2c59c984fee319d 324 SUPERFAMILY SSF51430 16 316 9.82E-69 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily MB46_04975 81d4bf4faff837aaf2c59c984fee319d 324 Gene3D G3DSA:3.20.20.100 6 324 1.4E-83 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily MB46_04975 81d4bf4faff837aaf2c59c984fee319d 324 PRINTS PR00069 Aldo-keto reductase signature 117 135 6.3E-7 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MB46_04975 81d4bf4faff837aaf2c59c984fee319d 324 PRINTS PR00069 Aldo-keto reductase signature 148 165 6.3E-7 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MB46_08510 d63904532350e63a7d184d71c04a95d7 148 Pfam PF01029 NusB family 17 140 1.3E-33 T 14-10-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 MB46_08510 d63904532350e63a7d184d71c04a95d7 148 Hamap MF_00073 Transcription antitermination protein NusB [nusB]. 14 144 21.423 T 14-10-2018 IPR011605 NusB antitermination factor GO:0006353 MB46_08510 d63904532350e63a7d184d71c04a95d7 148 SUPERFAMILY SSF48013 16 139 1.31E-36 T 14-10-2018 IPR035926 NusB-like superfamily MB46_08510 d63904532350e63a7d184d71c04a95d7 148 Gene3D G3DSA:1.10.940.10 8 139 2.4E-40 T 14-10-2018 IPR035926 NusB-like superfamily MB46_08510 d63904532350e63a7d184d71c04a95d7 148 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 16 140 3.8E-36 T 14-10-2018 IPR011605 NusB antitermination factor GO:0006353 MB46_05100 d027abf1ae2ff78c18e507309cc65ae1 373 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 17 360 7.5E-80 T 14-10-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 MB46_05100 d027abf1ae2ff78c18e507309cc65ae1 373 TIGRFAM TIGR00876 tal_mycobact: transaldolase 13 360 1.7E-122 T 14-10-2018 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 MB46_05100 d027abf1ae2ff78c18e507309cc65ae1 373 Hamap MF_00493 Transaldolase [tal]. 1 372 149.893 T 14-10-2018 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 MB46_05100 d027abf1ae2ff78c18e507309cc65ae1 373 Gene3D G3DSA:3.20.20.70 5 366 8.1E-150 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MB46_05100 d027abf1ae2ff78c18e507309cc65ae1 373 PIRSF PIRSF036915 1 372 1.7E-159 T 14-10-2018 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 MB46_05100 d027abf1ae2ff78c18e507309cc65ae1 373 ProSitePatterns PS01054 Transaldolase signature 1. 43 51 - T 14-10-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 MB46_05100 d027abf1ae2ff78c18e507309cc65ae1 373 SUPERFAMILY SSF51569 7 362 2.69E-75 T 14-10-2018 MB46_00760 3d25dfc3f06c99b70aa06e45b1ad5f62 295 Pfam PF13377 Periplasmic binding protein-like domain 134 291 5.1E-21 T 14-10-2018 MB46_00760 3d25dfc3f06c99b70aa06e45b1ad5f62 295 SUPERFAMILY SSF53822 32 278 5.78E-42 T 14-10-2018 IPR028082 Periplasmic binding protein-like I MB46_00760 3d25dfc3f06c99b70aa06e45b1ad5f62 295 Gene3D G3DSA:3.40.50.2300 125 252 5.0E-45 T 14-10-2018 MB46_00760 3d25dfc3f06c99b70aa06e45b1ad5f62 295 Gene3D G3DSA:3.40.50.2300 43 273 5.0E-45 T 14-10-2018 MB46_00595 2a3c3610bfaa28b95c27d16a7fc646d5 184 Pfam PF01965 DJ-1/PfpI family 8 181 1.5E-28 T 14-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 MB46_00595 2a3c3610bfaa28b95c27d16a7fc646d5 184 Gene3D G3DSA:3.40.50.880 1 184 2.1E-32 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like MB46_00595 2a3c3610bfaa28b95c27d16a7fc646d5 184 SUPERFAMILY SSF52317 7 182 1.25E-27 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like MB46_02415 91081c7ec3604780903c503822770cd2 387 Pfam PF06737 Transglycosylase-like domain 310 382 2.1E-29 T 14-10-2018 IPR010618 Transglycosylase-like MB46_02415 91081c7ec3604780903c503822770cd2 387 Pfam PF03990 Domain of unknown function (DUF348) 152 189 6.8E-9 T 14-10-2018 IPR007137 Resuscitation-promoting factor, domain of unknown function DUF348 MB46_02415 91081c7ec3604780903c503822770cd2 387 Pfam PF03990 Domain of unknown function (DUF348) 41 80 4.0E-7 T 14-10-2018 IPR007137 Resuscitation-promoting factor, domain of unknown function DUF348 MB46_02415 91081c7ec3604780903c503822770cd2 387 SMART SM01208 206 284 2.1E-18 T 14-10-2018 IPR011098 G5 domain MB46_02415 91081c7ec3604780903c503822770cd2 387 Pfam PF07501 G5 domain 211 283 5.4E-15 T 14-10-2018 IPR011098 G5 domain MB46_02415 91081c7ec3604780903c503822770cd2 387 SUPERFAMILY SSF53955 307 383 4.12E-28 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily MB46_02415 91081c7ec3604780903c503822770cd2 387 Gene3D G3DSA:2.20.230.10 190 283 8.8E-15 T 14-10-2018 MB46_02415 91081c7ec3604780903c503822770cd2 387 Gene3D G3DSA:1.10.530.10 310 387 3.9E-30 T 14-10-2018 MB46_17190 fd246dbcb321351defdf9011e2a75143 402 Pfam PF07730 Histidine kinase 213 279 1.5E-12 T 14-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 MB46_17190 fd246dbcb321351defdf9011e2a75143 402 Gene3D G3DSA:3.30.565.10 278 398 3.8E-23 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MB46_17190 fd246dbcb321351defdf9011e2a75143 402 SUPERFAMILY SSF55874 279 382 3.44E-6 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MB46_08375 9aa55e84d3788fe43614daf696a22fc4 169 Pfam PF02577 Bifunctional nuclease 6 128 1.6E-40 T 14-10-2018 IPR003729 Bifunctional nuclease domain GO:0004518 MB46_08375 9aa55e84d3788fe43614daf696a22fc4 169 SUPERFAMILY SSF103256 1 135 4.84E-41 T 14-10-2018 IPR036104 Bifunctional nuclease superfamily GO:0004518 MB46_08375 9aa55e84d3788fe43614daf696a22fc4 169 Gene3D G3DSA:3.10.690.10 1 139 2.8E-42 T 14-10-2018 IPR036104 Bifunctional nuclease superfamily GO:0004518 MB46_08315 ac3e35b18fa634a44888f90011a30e7a 479 Gene3D G3DSA:3.10.350.10 178 229 9.3E-14 T 14-10-2018 IPR036779 LysM domain superfamily MB46_08315 ac3e35b18fa634a44888f90011a30e7a 479 SUPERFAMILY SSF54106 247 291 4.05E-8 T 14-10-2018 MB46_08315 ac3e35b18fa634a44888f90011a30e7a 479 Pfam PF01464 Transglycosylase SLT domain 361 455 6.0E-17 T 14-10-2018 IPR008258 Transglycosylase SLT domain 1 MB46_08315 ac3e35b18fa634a44888f90011a30e7a 479 SMART SM00257 119 163 1.5E-10 T 14-10-2018 IPR018392 LysM domain MB46_08315 ac3e35b18fa634a44888f90011a30e7a 479 SMART SM00257 180 224 3.2E-11 T 14-10-2018 IPR018392 LysM domain MB46_08315 ac3e35b18fa634a44888f90011a30e7a 479 SMART SM00257 247 291 4.8E-10 T 14-10-2018 IPR018392 LysM domain MB46_08315 ac3e35b18fa634a44888f90011a30e7a 479 Gene3D G3DSA:3.10.350.10 104 177 5.1E-14 T 14-10-2018 IPR036779 LysM domain superfamily MB46_08315 ac3e35b18fa634a44888f90011a30e7a 479 Gene3D G3DSA:3.10.350.10 231 300 1.7E-13 T 14-10-2018 IPR036779 LysM domain superfamily MB46_08315 ac3e35b18fa634a44888f90011a30e7a 479 Pfam PF01476 LysM domain 248 291 2.5E-12 T 14-10-2018 IPR018392 LysM domain MB46_08315 ac3e35b18fa634a44888f90011a30e7a 479 Pfam PF01476 LysM domain 181 223 8.0E-12 T 14-10-2018 IPR018392 LysM domain MB46_08315 ac3e35b18fa634a44888f90011a30e7a 479 Pfam PF01476 LysM domain 120 162 8.4E-11 T 14-10-2018 IPR018392 LysM domain MB46_08315 ac3e35b18fa634a44888f90011a30e7a 479 SUPERFAMILY SSF54106 118 162 7.46E-8 T 14-10-2018 MB46_08315 ac3e35b18fa634a44888f90011a30e7a 479 SUPERFAMILY SSF53955 344 474 1.28E-23 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily MB46_08315 ac3e35b18fa634a44888f90011a30e7a 479 SUPERFAMILY SSF54106 180 223 4.97E-9 T 14-10-2018 MB46_08315 ac3e35b18fa634a44888f90011a30e7a 479 Gene3D G3DSA:1.10.530.10 339 473 1.5E-22 T 14-10-2018 MB46_13730 c84e43a07086d7b54754f7c101bdae53 146 Gene3D G3DSA:3.10.129.10 3 146 2.8E-42 T 14-10-2018 MB46_13730 c84e43a07086d7b54754f7c101bdae53 146 SUPERFAMILY SSF54637 2 143 5.97E-28 T 14-10-2018 IPR029069 HotDog domain superfamily MB46_13730 c84e43a07086d7b54754f7c101bdae53 146 PRINTS PR01483 Fatty acid synthase signature 48 69 5.8E-8 T 14-10-2018 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 MB46_13730 c84e43a07086d7b54754f7c101bdae53 146 PRINTS PR01483 Fatty acid synthase signature 26 48 5.8E-8 T 14-10-2018 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 MB46_13730 c84e43a07086d7b54754f7c101bdae53 146 Pfam PF01575 MaoC like domain 14 97 5.8E-24 T 14-10-2018 IPR002539 MaoC-like dehydratase domain MB46_04380 b0a6ddba6b58e0d1b8034ed58f2ee9b8 211 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 25 39 2.7E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MB46_04380 b0a6ddba6b58e0d1b8034ed58f2ee9b8 211 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 39 55 2.7E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MB46_04380 b0a6ddba6b58e0d1b8034ed58f2ee9b8 211 Gene3D G3DSA:1.20.120.530 70 211 2.7E-22 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MB46_04380 b0a6ddba6b58e0d1b8034ed58f2ee9b8 211 Pfam PF00392 Bacterial regulatory proteins, gntR family 4 65 1.5E-16 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MB46_04380 b0a6ddba6b58e0d1b8034ed58f2ee9b8 211 SUPERFAMILY SSF48008 71 208 3.4E-18 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MB46_04380 b0a6ddba6b58e0d1b8034ed58f2ee9b8 211 SUPERFAMILY SSF46785 4 91 5.28E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_04380 b0a6ddba6b58e0d1b8034ed58f2ee9b8 211 SMART SM00345 7 65 1.7E-13 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MB46_04380 b0a6ddba6b58e0d1b8034ed58f2ee9b8 211 Pfam PF07729 FCD domain 75 200 1.6E-18 T 14-10-2018 IPR011711 GntR, C-terminal MB46_04380 b0a6ddba6b58e0d1b8034ed58f2ee9b8 211 Gene3D G3DSA:1.10.10.10 1 67 1.9E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_04380 b0a6ddba6b58e0d1b8034ed58f2ee9b8 211 SMART SM00895 75 201 1.1E-10 T 14-10-2018 IPR011711 GntR, C-terminal MB46_04180 7bdefb8a96cf94a5b37ae9092dfeda92 63 SUPERFAMILY SSF55331 2 60 4.97E-16 T 14-10-2018 IPR014347 Tautomerase/MIF superfamily MB46_04180 7bdefb8a96cf94a5b37ae9092dfeda92 63 Gene3D G3DSA:3.30.429.10 1 63 9.2E-20 T 14-10-2018 IPR014347 Tautomerase/MIF superfamily MB46_04180 7bdefb8a96cf94a5b37ae9092dfeda92 63 Pfam PF01361 Tautomerase enzyme 2 59 1.1E-14 T 14-10-2018 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 MB46_13250 4fd3e0a2c00867b504ce588d2a4ed8bb 135 TIGRFAM TIGR00220 mscL: large conductance mechanosensitive channel protein 1 127 3.1E-32 T 14-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 MB46_13250 4fd3e0a2c00867b504ce588d2a4ed8bb 135 SUPERFAMILY SSF81330 10 123 1.09E-29 T 14-10-2018 IPR036019 Gated mechanosensitive channel MB46_13250 4fd3e0a2c00867b504ce588d2a4ed8bb 135 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 76 84 1.0E-8 T 14-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 MB46_13250 4fd3e0a2c00867b504ce588d2a4ed8bb 135 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 4 18 1.0E-8 T 14-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 MB46_13250 4fd3e0a2c00867b504ce588d2a4ed8bb 135 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 86 95 1.0E-8 T 14-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 MB46_13250 4fd3e0a2c00867b504ce588d2a4ed8bb 135 ProSitePatterns PS01327 Large-conductance mechanosensitive channels mscL family signature. 11 24 - T 14-10-2018 IPR019823 Large-conductance mechanosensitive channel, conserved site MB46_13250 4fd3e0a2c00867b504ce588d2a4ed8bb 135 Gene3D G3DSA:1.10.1200.120 1 129 1.9E-38 T 14-10-2018 IPR036019 Gated mechanosensitive channel MB46_13250 4fd3e0a2c00867b504ce588d2a4ed8bb 135 Pfam PF01741 Large-conductance mechanosensitive channel, MscL 1 127 4.7E-38 T 14-10-2018 IPR037673 Large-conductance mechanosensitive channel/anditomin synthesis protein L MB46_13250 4fd3e0a2c00867b504ce588d2a4ed8bb 135 Hamap MF_00115 Large-conductance mechanosensitive channel [mscL]. 1 128 22.122 T 14-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 MB46_13505 6e964d782eb553fd8eb30681f0f4d74b 366 SUPERFAMILY SSF55729 182 359 5.23E-7 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase MB46_13505 6e964d782eb553fd8eb30681f0f4d74b 366 Gene3D G3DSA:3.40.630.30 5 365 2.5E-77 T 14-10-2018 MB46_13505 6e964d782eb553fd8eb30681f0f4d74b 366 SUPERFAMILY SSF55729 20 134 2.7E-12 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase MB46_13505 6e964d782eb553fd8eb30681f0f4d74b 366 Pfam PF00583 Acetyltransferase (GNAT) family 49 133 6.3E-7 T 14-10-2018 IPR000182 GNAT domain MB46_02075 e38b0f9fc42662e58dc188000041d1d6 412 Gene3D G3DSA:3.30.70.260 336 405 1.6E-6 T 14-10-2018 MB46_02075 e38b0f9fc42662e58dc188000041d1d6 412 Gene3D G3DSA:3.40.50.1100 57 153 2.8E-115 T 14-10-2018 MB46_02075 e38b0f9fc42662e58dc188000041d1d6 412 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 23 313 8.1E-82 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme MB46_02075 e38b0f9fc42662e58dc188000041d1d6 412 SUPERFAMILY SSF55021 337 403 4.28E-7 T 14-10-2018 MB46_02075 e38b0f9fc42662e58dc188000041d1d6 412 TIGRFAM TIGR01127 ilvA_1Cterm: threonine ammonia-lyase 28 407 1.9E-139 T 14-10-2018 IPR005789 Threonine dehydratase, catabolic GO:0004794|GO:0006567 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 MB46_02075 e38b0f9fc42662e58dc188000041d1d6 412 Pfam PF01842 ACT domain 337 403 8.5E-7 T 14-10-2018 IPR002912 ACT domain MB46_02075 e38b0f9fc42662e58dc188000041d1d6 412 Gene3D G3DSA:3.40.50.1100 14 317 2.8E-115 T 14-10-2018 MB46_02075 e38b0f9fc42662e58dc188000041d1d6 412 SUPERFAMILY SSF53686 10 320 3.4E-95 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme MB46_02235 30ae29b4820c1083fa4785d975dc7f00 384 SUPERFAMILY SSF56059 102 303 3.71E-58 T 14-10-2018 MB46_02235 30ae29b4820c1083fa4785d975dc7f00 384 SUPERFAMILY SSF52440 4 97 1.87E-23 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily MB46_02235 30ae29b4820c1083fa4785d975dc7f00 384 Gene3D G3DSA:3.30.470.20 106 360 9.0E-86 T 14-10-2018 MB46_02235 30ae29b4820c1083fa4785d975dc7f00 384 Pfam PF02222 ATP-grasp domain 111 283 8.2E-49 T 14-10-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type MB46_02235 30ae29b4820c1083fa4785d975dc7f00 384 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 5 363 38.785 T 14-10-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 MB46_02235 30ae29b4820c1083fa4785d975dc7f00 384 Gene3D G3DSA:3.30.1490.20 117 181 9.0E-86 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 MB46_02235 30ae29b4820c1083fa4785d975dc7f00 384 Gene3D G3DSA:3.40.50.20 2 105 6.8E-30 T 14-10-2018 MB46_02235 30ae29b4820c1083fa4785d975dc7f00 384 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 6 367 7.1E-107 T 14-10-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 MB46_02235 30ae29b4820c1083fa4785d975dc7f00 384 SUPERFAMILY SSF51246 311 371 2.9E-12 T 14-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 MB46_03720 e9e0bd09691ab7589a0612b82737411f 597 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 96 488 9.3E-39 T 14-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 MB46_03720 e9e0bd09691ab7589a0612b82737411f 597 SUPERFAMILY SSF55826 257 409 3.66E-7 T 14-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 MB46_03720 e9e0bd09691ab7589a0612b82737411f 597 Gene3D G3DSA:3.30.930.10 13 494 6.2E-206 T 14-10-2018 MB46_03720 e9e0bd09691ab7589a0612b82737411f 597 SUPERFAMILY SSF52954 492 595 4.25E-25 T 14-10-2018 MB46_03720 e9e0bd09691ab7589a0612b82737411f 597 Gene3D G3DSA:3.40.50.800 6 580 6.2E-206 T 14-10-2018 IPR036621 Anticodon-binding domain superfamily MB46_03720 e9e0bd09691ab7589a0612b82737411f 597 SUPERFAMILY SSF55681 12 507 3.21E-87 T 14-10-2018 MB46_03720 e9e0bd09691ab7589a0612b82737411f 597 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 3 594 7.5E-160 T 14-10-2018 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 MB46_03720 e9e0bd09691ab7589a0612b82737411f 597 PRINTS PR01046 Prolyl-tRNA synthetase signature 146 157 4.5E-15 T 14-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 MB46_03720 e9e0bd09691ab7589a0612b82737411f 597 PRINTS PR01046 Prolyl-tRNA synthetase signature 70 88 4.5E-15 T 14-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 MB46_03720 e9e0bd09691ab7589a0612b82737411f 597 PRINTS PR01046 Prolyl-tRNA synthetase signature 136 144 4.5E-15 T 14-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 MB46_03720 e9e0bd09691ab7589a0612b82737411f 597 PRINTS PR01046 Prolyl-tRNA synthetase signature 106 117 4.5E-15 T 14-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 MB46_03720 e9e0bd09691ab7589a0612b82737411f 597 Pfam PF04073 Aminoacyl-tRNA editing domain 258 408 7.1E-19 T 14-10-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 MB46_03720 e9e0bd09691ab7589a0612b82737411f 597 Pfam PF03129 Anticodon binding domain 504 595 2.4E-14 T 14-10-2018 IPR004154 Anticodon-binding MB46_03720 e9e0bd09691ab7589a0612b82737411f 597 Gene3D G3DSA:3.90.960.10 241 418 6.2E-206 T 14-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 MB46_03720 e9e0bd09691ab7589a0612b82737411f 597 Hamap MF_01569 Proline--tRNA ligase [proS]. 3 597 36.291 T 14-10-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 MB46_18885 38240cc6cf430c9796ffc98859e2edcf 386 SUPERFAMILY SSF48317 146 264 2.09E-22 T 14-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily MB46_18885 38240cc6cf430c9796ffc98859e2edcf 386 Gene3D G3DSA:1.20.144.10 70 269 1.1E-53 T 14-10-2018 MB46_18885 38240cc6cf430c9796ffc98859e2edcf 386 Pfam PF01569 PAP2 superfamily 148 246 1.2E-9 T 14-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MB46_18885 38240cc6cf430c9796ffc98859e2edcf 386 ProSitePatterns PS01157 Class A bacterial acid phosphatases signature. 184 191 - T 14-10-2018 IPR018296 Acid phosphatase, class A, bacterial, conserved site GO:0003993|GO:0030288 KEGG: 00730+3.1.3.2|KEGG: 00740+3.1.3.2|MetaCyc: PWY-6348 MB46_03185 db68a561d0e237c0968feb9ae5d64edb 212 Gene3D G3DSA:3.10.180.10 1 149 2.2E-8 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MB46_03185 db68a561d0e237c0968feb9ae5d64edb 212 Pfam PF13468 Glyoxalase-like domain 3 174 2.2E-34 T 14-10-2018 IPR025870 Glyoxalase-like domain MB46_00635 41ad743fb5839e509e3bb4b2a7280554 510 SUPERFAMILY SSF49503 68 193 1.16E-32 T 14-10-2018 IPR008972 Cupredoxin MB46_00635 41ad743fb5839e509e3bb4b2a7280554 510 SUPERFAMILY SSF49503 384 491 7.25E-29 T 14-10-2018 IPR008972 Cupredoxin MB46_00635 41ad743fb5839e509e3bb4b2a7280554 510 ProSitePatterns PS00080 Multicopper oxidases signature 2. 475 486 - T 14-10-2018 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 MB46_00635 41ad743fb5839e509e3bb4b2a7280554 510 Gene3D G3DSA:2.60.40.420 197 346 3.8E-39 T 14-10-2018 IPR008972 Cupredoxin MB46_00635 41ad743fb5839e509e3bb4b2a7280554 510 Pfam PF07732 Multicopper oxidase 94 194 9.9E-29 T 14-10-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 MB46_00635 41ad743fb5839e509e3bb4b2a7280554 510 SUPERFAMILY SSF49503 199 316 5.12E-21 T 14-10-2018 IPR008972 Cupredoxin MB46_00635 41ad743fb5839e509e3bb4b2a7280554 510 Gene3D G3DSA:2.60.40.420 372 499 3.0E-38 T 14-10-2018 IPR008972 Cupredoxin MB46_00635 41ad743fb5839e509e3bb4b2a7280554 510 Gene3D G3DSA:2.60.40.420 55 196 1.2E-43 T 14-10-2018 IPR008972 Cupredoxin MB46_00635 41ad743fb5839e509e3bb4b2a7280554 510 Pfam PF07731 Multicopper oxidase 382 493 4.4E-24 T 14-10-2018 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 MB46_18410 24db492af7e1f67ed514affedd64376f 392 Gene3D G3DSA:1.20.140.10 239 391 8.0E-35 T 14-10-2018 MB46_18410 24db492af7e1f67ed514affedd64376f 392 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 22 120 1.1E-15 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MB46_18410 24db492af7e1f67ed514affedd64376f 392 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 243 385 2.0E-24 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MB46_18410 24db492af7e1f67ed514affedd64376f 392 Gene3D G3DSA:1.10.540.10 2 122 5.2E-21 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 MB46_18410 24db492af7e1f67ed514affedd64376f 392 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 127 224 2.6E-19 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MB46_18410 24db492af7e1f67ed514affedd64376f 392 SUPERFAMILY SSF56645 7 235 5.76E-52 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 MB46_18410 24db492af7e1f67ed514affedd64376f 392 SUPERFAMILY SSF47203 241 388 1.93E-35 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 MB46_18410 24db492af7e1f67ed514affedd64376f 392 Gene3D G3DSA:2.40.110.10 126 235 3.4E-28 T 14-10-2018 MB46_02295 75602adf8de9d1292c1ae552686f8a5a 325 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 152 320 4.1E-17 T 14-10-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type MB46_02295 75602adf8de9d1292c1ae552686f8a5a 325 TIGRFAM TIGR03086 TIGR03086: TIGR03086 family protein 153 320 7.4E-33 T 14-10-2018 IPR017520 Conserved hypothetical protein CHP03086 MB46_02295 75602adf8de9d1292c1ae552686f8a5a 325 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 11 128 9.6E-27 T 14-10-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like MB46_02295 75602adf8de9d1292c1ae552686f8a5a 325 SUPERFAMILY SSF109854 152 267 6.41E-10 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes MB46_02295 75602adf8de9d1292c1ae552686f8a5a 325 Gene3D G3DSA:3.30.530.20 1 141 1.1E-35 T 14-10-2018 IPR023393 START-like domain superfamily MB46_02295 75602adf8de9d1292c1ae552686f8a5a 325 SUPERFAMILY SSF55961 1 137 2.89E-30 T 14-10-2018 MB46_02710 91f2055ac4f46f6b24c29ce50670eb3d 237 SUPERFAMILY SSF55781 16 152 1.92E-13 T 14-10-2018 MB46_02710 91f2055ac4f46f6b24c29ce50670eb3d 237 Pfam PF03861 ANTAR domain 167 218 3.2E-9 T 14-10-2018 IPR005561 ANTAR domain GO:0003723 MB46_02710 91f2055ac4f46f6b24c29ce50670eb3d 237 Pfam PF13185 GAF domain 44 144 2.9E-8 T 14-10-2018 IPR003018 GAF domain GO:0005515 MB46_02710 91f2055ac4f46f6b24c29ce50670eb3d 237 Gene3D G3DSA:3.30.450.40 9 152 7.0E-12 T 14-10-2018 IPR029016 GAF-like domain superfamily MB46_02710 91f2055ac4f46f6b24c29ce50670eb3d 237 SUPERFAMILY SSF52172 162 218 8.95E-5 T 14-10-2018 IPR011006 CheY-like superfamily MB46_02710 91f2055ac4f46f6b24c29ce50670eb3d 237 SMART SM01012 163 218 3.3E-11 T 14-10-2018 IPR005561 ANTAR domain GO:0003723 MB46_14735 4068945bc4978dbf86203daf8840dfed 155 Pfam PF00578 AhpC/TSA family 8 135 1.2E-38 T 14-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 MB46_14735 4068945bc4978dbf86203daf8840dfed 155 SUPERFAMILY SSF52833 3 150 1.43E-47 T 14-10-2018 IPR036249 Thioredoxin-like superfamily MB46_14735 4068945bc4978dbf86203daf8840dfed 155 Gene3D G3DSA:3.40.30.10 3 154 4.2E-46 T 14-10-2018 MB46_14735 4068945bc4978dbf86203daf8840dfed 155 PIRSF PIRSF000239 2 152 1.5E-19 T 14-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 MB46_11850 3145a2e8aa9ff059d099c98547124aca 347 Pfam PF03459 TOBE domain 287 343 3.2E-9 T 14-10-2018 IPR005116 Transport-associated OB, type 1 MB46_11850 3145a2e8aa9ff059d099c98547124aca 347 Gene3D G3DSA:2.40.50.100 286 344 1.1E-6 T 14-10-2018 MB46_11850 3145a2e8aa9ff059d099c98547124aca 347 SUPERFAMILY SSF50331 235 345 7.23E-15 T 14-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal MB46_11850 3145a2e8aa9ff059d099c98547124aca 347 SMART SM00382 22 210 5.1E-18 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_11850 3145a2e8aa9ff059d099c98547124aca 347 Pfam PF00005 ABC transporter 15 163 8.0E-33 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_11850 3145a2e8aa9ff059d099c98547124aca 347 SUPERFAMILY SSF52540 13 234 3.29E-60 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_11850 3145a2e8aa9ff059d099c98547124aca 347 Gene3D G3DSA:3.40.50.300 7 236 1.2E-63 T 14-10-2018 MB46_03900 50c5b1ca6886c160820e8ac5ba6b5bbb 146 SMART SM00530 42 97 8.1E-8 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MB46_03900 50c5b1ca6886c160820e8ac5ba6b5bbb 146 Pfam PF13560 Helix-turn-helix domain 38 95 7.5E-11 T 14-10-2018 MB46_03900 50c5b1ca6886c160820e8ac5ba6b5bbb 146 SUPERFAMILY SSF47413 32 101 1.24E-12 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MB46_03900 50c5b1ca6886c160820e8ac5ba6b5bbb 146 Gene3D G3DSA:1.10.260.40 33 108 2.5E-15 T 14-10-2018 MB46_00900 f1b53ebfe8833729effc0ac6a08b8dda 218 SUPERFAMILY SSF52141 3 214 2.83E-71 T 14-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MB46_00900 f1b53ebfe8833729effc0ac6a08b8dda 218 Pfam PF03167 Uracil DNA glycosylase superfamily 50 202 8.7E-18 T 14-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MB46_00900 f1b53ebfe8833729effc0ac6a08b8dda 218 Hamap MF_00148 Uracil-DNA glycosylase [ung]. 2 214 34.657 T 14-10-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MB46_00900 f1b53ebfe8833729effc0ac6a08b8dda 218 TIGRFAM TIGR00628 ung: uracil-DNA glycosylase 4 206 6.3E-60 T 14-10-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MB46_00900 f1b53ebfe8833729effc0ac6a08b8dda 218 Gene3D G3DSA:3.40.470.10 1 216 5.2E-82 T 14-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MB46_00900 f1b53ebfe8833729effc0ac6a08b8dda 218 SMART SM00987 44 203 9.9E-28 T 14-10-2018 MB46_00900 f1b53ebfe8833729effc0ac6a08b8dda 218 ProSitePatterns PS00130 Uracil-DNA glycosylase signature. 52 61 - T 14-10-2018 IPR018085 Uracil-DNA glycosylase, active site GO:0006281|GO:0016799 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MB46_00900 f1b53ebfe8833729effc0ac6a08b8dda 218 SMART SM00986 44 203 9.9E-28 T 14-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MB46_14535 5ee94f8ed5793f5c3489fef876552dcb 311 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 304 1.0E-11 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_14535 5ee94f8ed5793f5c3489fef876552dcb 311 Gene3D G3DSA:1.10.3720.10 24 302 6.4E-60 T 14-10-2018 IPR035906 MetI-like superfamily MB46_14535 5ee94f8ed5793f5c3489fef876552dcb 311 SUPERFAMILY SSF161098 32 311 5.89E-52 T 14-10-2018 IPR035906 MetI-like superfamily MB46_06485 66bd57cf065fed44f5bd05aadb914a57 263 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MB46_06485 66bd57cf065fed44f5bd05aadb914a57 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 2.8E-23 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_06485 66bd57cf065fed44f5bd05aadb914a57 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 2.8E-23 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_06485 66bd57cf065fed44f5bd05aadb914a57 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 2.8E-23 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_06485 66bd57cf065fed44f5bd05aadb914a57 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 2.8E-23 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_06485 66bd57cf065fed44f5bd05aadb914a57 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 2.8E-23 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_06485 66bd57cf065fed44f5bd05aadb914a57 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 242 2.8E-23 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_06485 66bd57cf065fed44f5bd05aadb914a57 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 4.1E-5 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_06485 66bd57cf065fed44f5bd05aadb914a57 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 4.1E-5 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_06485 66bd57cf065fed44f5bd05aadb914a57 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 4.1E-5 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_06485 66bd57cf065fed44f5bd05aadb914a57 263 SUPERFAMILY SSF51735 1 259 4.5E-57 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_06485 66bd57cf065fed44f5bd05aadb914a57 263 Pfam PF00106 short chain dehydrogenase 8 195 3.3E-39 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_06485 66bd57cf065fed44f5bd05aadb914a57 263 Gene3D G3DSA:3.40.50.720 2 262 9.6E-62 T 14-10-2018 MB46_08975 32e3cd880379aef95f3b4948410223ea 1056 SUPERFAMILY SSF50249 430 513 2.29E-16 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold MB46_08975 32e3cd880379aef95f3b4948410223ea 1056 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 405 805 7.2E-150 T 14-10-2018 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 MB46_08975 32e3cd880379aef95f3b4948410223ea 1056 SMART SM00316 428 507 1.8E-7 T 14-10-2018 IPR022967 RNA-binding domain, S1 MB46_08975 32e3cd880379aef95f3b4948410223ea 1056 Gene3D G3DSA:2.40.50.140 421 513 7.6E-28 T 14-10-2018 MB46_08975 32e3cd880379aef95f3b4948410223ea 1056 Pfam PF10150 Ribonuclease E/G family 509 780 2.2E-103 T 14-10-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 MB46_01465 152b15a33876138d13e600d186e3c1ec 352 Pfam PF00145 C-5 cytosine-specific DNA methylase 1 345 2.1E-49 T 14-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 MB46_01465 152b15a33876138d13e600d186e3c1ec 352 ProSitePatterns PS00094 C-5 cytosine-specific DNA methylases active site. 74 86 - T 14-10-2018 IPR018117 DNA methylase, C-5 cytosine-specific, active site KEGG: 00270+2.1.1.37|Reactome: R-HSA-212300|Reactome: R-HSA-4655427|Reactome: R-HSA-5334118 MB46_01465 152b15a33876138d13e600d186e3c1ec 352 Gene3D G3DSA:3.90.120.10 155 335 8.3E-70 T 14-10-2018 MB46_01465 152b15a33876138d13e600d186e3c1ec 352 SUPERFAMILY SSF53335 1 346 7.95E-69 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MB46_01465 152b15a33876138d13e600d186e3c1ec 352 Gene3D G3DSA:3.40.50.150 1 338 8.3E-70 T 14-10-2018 MB46_01465 152b15a33876138d13e600d186e3c1ec 352 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 112 126 3.4E-8 T 14-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 MB46_01465 152b15a33876138d13e600d186e3c1ec 352 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 159 172 3.4E-8 T 14-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 MB46_01465 152b15a33876138d13e600d186e3c1ec 352 TIGRFAM TIGR00675 dcm: DNA (cytosine-5-)-methyltransferase 1 341 1.2E-42 T 14-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 MB46_09885 fd6ee1c0aebcda5fe7f4998e1407556b 252 Pfam PF12697 Alpha/beta hydrolase family 22 240 3.9E-17 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MB46_09885 fd6ee1c0aebcda5fe7f4998e1407556b 252 SUPERFAMILY SSF53474 1 250 4.05E-54 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_09885 fd6ee1c0aebcda5fe7f4998e1407556b 252 PRINTS PR00111 Alpha/beta hydrolase fold signature 103 116 9.4E-10 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MB46_09885 fd6ee1c0aebcda5fe7f4998e1407556b 252 PRINTS PR00111 Alpha/beta hydrolase fold signature 196 210 9.4E-10 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MB46_09885 fd6ee1c0aebcda5fe7f4998e1407556b 252 PRINTS PR00111 Alpha/beta hydrolase fold signature 45 60 9.4E-10 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MB46_09885 fd6ee1c0aebcda5fe7f4998e1407556b 252 PRINTS PR00111 Alpha/beta hydrolase fold signature 89 102 9.4E-10 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MB46_09885 fd6ee1c0aebcda5fe7f4998e1407556b 252 Gene3D G3DSA:3.40.50.1820 1 252 4.1E-52 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_08020 9be7a96f1f804da30b7c43c3b492942b 971 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 909 923 1.0E-10 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_08020 9be7a96f1f804da30b7c43c3b492942b 971 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 923 939 1.0E-10 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_08020 9be7a96f1f804da30b7c43c3b492942b 971 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 939 951 1.0E-10 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_08020 9be7a96f1f804da30b7c43c3b492942b 971 SUPERFAMILY SSF46894 909 966 6.12E-19 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MB46_08020 9be7a96f1f804da30b7c43c3b492942b 971 SMART SM00421 906 963 9.1E-26 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_08020 9be7a96f1f804da30b7c43c3b492942b 971 Pfam PF00196 Bacterial regulatory proteins, luxR family 910 963 1.1E-21 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_08020 9be7a96f1f804da30b7c43c3b492942b 971 Gene3D G3DSA:1.10.10.10 890 968 4.2E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_08020 9be7a96f1f804da30b7c43c3b492942b 971 ProSitePatterns PS00622 LuxR-type HTH domain signature. 923 950 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_08020 9be7a96f1f804da30b7c43c3b492942b 971 SUPERFAMILY SSF52540 22 240 1.85E-9 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_08020 9be7a96f1f804da30b7c43c3b492942b 971 Gene3D G3DSA:3.40.50.300 13 202 1.0E-6 T 14-10-2018 MB46_08020 9be7a96f1f804da30b7c43c3b492942b 971 Pfam PF13191 AAA ATPase domain 25 188 2.7E-24 T 14-10-2018 MB46_08020 9be7a96f1f804da30b7c43c3b492942b 971 SUPERFAMILY SSF48452 508 713 5.22E-9 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MB46_09815 831162b8c7d647888c5894637f682dd8 754 SMART SM00487 281 482 4.8E-27 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MB46_09815 831162b8c7d647888c5894637f682dd8 754 Pfam PF00271 Helicase conserved C-terminal domain 566 642 9.6E-16 T 14-10-2018 IPR001650 Helicase, C-terminal MB46_09815 831162b8c7d647888c5894637f682dd8 754 SUPERFAMILY SSF50249 17 179 1.66E-17 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold MB46_09815 831162b8c7d647888c5894637f682dd8 754 Pfam PF00270 DEAD/DEAH box helicase 308 458 5.5E-16 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MB46_09815 831162b8c7d647888c5894637f682dd8 754 Gene3D G3DSA:3.40.50.300 223 472 1.0E-77 T 14-10-2018 MB46_09815 831162b8c7d647888c5894637f682dd8 754 Gene3D G3DSA:3.40.50.300 485 683 4.1E-48 T 14-10-2018 MB46_09815 831162b8c7d647888c5894637f682dd8 754 Pfam PF17191 RecG wedge domain 26 149 7.2E-7 T 14-10-2018 IPR033454 RecG, wedge domain MB46_09815 831162b8c7d647888c5894637f682dd8 754 SUPERFAMILY SSF52540 306 695 1.43E-40 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_09815 831162b8c7d647888c5894637f682dd8 754 SMART SM00490 556 642 4.8E-19 T 14-10-2018 IPR001650 Helicase, C-terminal MB46_09815 831162b8c7d647888c5894637f682dd8 754 SUPERFAMILY SSF52540 201 475 2.48E-51 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_09815 831162b8c7d647888c5894637f682dd8 754 Gene3D G3DSA:2.40.50.140 57 156 1.1E-11 T 14-10-2018 MB46_19575 d502eae4c0cbd63cb81ae14b42636893 499 Pfam PF12846 AAA-like domain 138 333 6.1E-7 T 14-10-2018 MB46_19575 d502eae4c0cbd63cb81ae14b42636893 499 SUPERFAMILY SSF52540 94 490 1.92E-32 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_19575 d502eae4c0cbd63cb81ae14b42636893 499 Gene3D G3DSA:3.40.50.300 104 224 8.0E-9 T 14-10-2018 MB46_19575 d502eae4c0cbd63cb81ae14b42636893 499 Gene3D G3DSA:3.40.50.300 300 494 9.3E-20 T 14-10-2018 MB46_02970 0b70a7a9de52ce28ca9a21a31b0a1544 763 SUPERFAMILY SSF50249 346 425 2.4E-25 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold MB46_02970 0b70a7a9de52ce28ca9a21a31b0a1544 763 Gene3D G3DSA:3.40.50.10190 667 753 2.6E-26 T 14-10-2018 IPR036420 BRCT domain superfamily MB46_02970 0b70a7a9de52ce28ca9a21a31b0a1544 763 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 39 495 4.1E-171 T 14-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 MB46_02970 0b70a7a9de52ce28ca9a21a31b0a1544 763 SUPERFAMILY SSF47781 566 668 3.11E-23 T 14-10-2018 IPR010994 RuvA domain 2-like MB46_02970 0b70a7a9de52ce28ca9a21a31b0a1544 763 Gene3D G3DSA:2.40.50.140 348 437 9.9E-31 T 14-10-2018 MB46_02970 0b70a7a9de52ce28ca9a21a31b0a1544 763 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 680 750 4.0E-11 T 14-10-2018 IPR001357 BRCT domain MB46_02970 0b70a7a9de52ce28ca9a21a31b0a1544 763 SMART SM00292 677 754 1.2E-13 T 14-10-2018 IPR001357 BRCT domain MB46_02970 0b70a7a9de52ce28ca9a21a31b0a1544 763 Gene3D G3DSA:1.10.287.610 23 95 1.9E-22 T 14-10-2018 MB46_02970 0b70a7a9de52ce28ca9a21a31b0a1544 763 SMART SM00532 31 481 7.1E-239 T 14-10-2018 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 MB46_02970 0b70a7a9de52ce28ca9a21a31b0a1544 763 Gene3D G3DSA:1.10.150.20 584 666 4.0E-23 T 14-10-2018 MB46_02970 0b70a7a9de52ce28ca9a21a31b0a1544 763 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 351 425 8.1E-30 T 14-10-2018 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 MB46_02970 0b70a7a9de52ce28ca9a21a31b0a1544 763 SUPERFAMILY SSF56091 29 345 1.28E-110 T 14-10-2018 MB46_02970 0b70a7a9de52ce28ca9a21a31b0a1544 763 Pfam PF12826 Helix-hairpin-helix motif 590 658 1.3E-15 T 14-10-2018 MB46_02970 0b70a7a9de52ce28ca9a21a31b0a1544 763 Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain 439 466 1.6E-7 T 14-10-2018 IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type GO:0003911|GO:0006260|GO:0006281 MB46_02970 0b70a7a9de52ce28ca9a21a31b0a1544 763 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 32 347 2.4E-118 T 14-10-2018 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 MB46_02970 0b70a7a9de52ce28ca9a21a31b0a1544 763 Gene3D G3DSA:3.30.470.90 96 347 2.4E-98 T 14-10-2018 MB46_02970 0b70a7a9de52ce28ca9a21a31b0a1544 763 PIRSF PIRSF001604 24 755 3.8E-218 T 14-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 MB46_02970 0b70a7a9de52ce28ca9a21a31b0a1544 763 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 360 375 - T 14-10-2018 IPR033136 NAD-dependent DNA ligase, conserved site MB46_02970 0b70a7a9de52ce28ca9a21a31b0a1544 763 SUPERFAMILY SSF52113 679 754 7.85E-18 T 14-10-2018 IPR036420 BRCT domain superfamily MB46_02970 0b70a7a9de52ce28ca9a21a31b0a1544 763 SUPERFAMILY SSF47781 435 495 4.67E-11 T 14-10-2018 IPR010994 RuvA domain 2-like MB46_02970 0b70a7a9de52ce28ca9a21a31b0a1544 763 Hamap MF_01588 DNA ligase [ligA]. 30 751 48.005 T 14-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 MB46_02970 0b70a7a9de52ce28ca9a21a31b0a1544 763 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 145 174 - T 14-10-2018 IPR018239 NAD-dependent DNA ligase, active site MB46_19075 99138573afcaaa8c134f84038169fc69 173 TIGRFAM TIGR00151 ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 5 158 1.1E-41 T 14-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 MB46_19075 99138573afcaaa8c134f84038169fc69 173 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 4 159 29.979 T 14-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 MB46_19075 99138573afcaaa8c134f84038169fc69 173 Pfam PF02542 YgbB family 5 157 8.0E-44 T 14-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 MB46_19075 99138573afcaaa8c134f84038169fc69 173 ProSitePatterns PS01350 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. 41 56 - T 14-10-2018 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site GO:0008685 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 MB46_19075 99138573afcaaa8c134f84038169fc69 173 Gene3D G3DSA:3.30.1330.50 1 165 6.7E-55 T 14-10-2018 IPR036571 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 MB46_19075 99138573afcaaa8c134f84038169fc69 173 SUPERFAMILY SSF69765 2 159 4.84E-48 T 14-10-2018 IPR036571 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 MB46_01385 a76a4029efb44c476296dec97a3fc623 512 Pfam PF00005 ABC transporter 281 436 1.0E-15 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_01385 a76a4029efb44c476296dec97a3fc623 512 SUPERFAMILY SSF52540 249 497 2.01E-41 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_01385 a76a4029efb44c476296dec97a3fc623 512 Gene3D G3DSA:3.40.50.300 1 241 1.3E-52 T 14-10-2018 MB46_01385 a76a4029efb44c476296dec97a3fc623 512 Gene3D G3DSA:3.40.50.300 259 511 1.8E-39 T 14-10-2018 MB46_01385 a76a4029efb44c476296dec97a3fc623 512 SUPERFAMILY SSF52540 8 222 1.74E-52 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_01385 a76a4029efb44c476296dec97a3fc623 512 ProSitePatterns PS00211 ABC transporters family signature. 409 423 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_01385 a76a4029efb44c476296dec97a3fc623 512 SMART SM00382 30 220 1.2E-8 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_01385 a76a4029efb44c476296dec97a3fc623 512 SMART SM00382 289 484 4.7E-4 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_01385 a76a4029efb44c476296dec97a3fc623 512 Pfam PF00005 ABC transporter 21 172 4.8E-29 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_16820 e7a6c0a29bccd9c58a84d5d3784d79b8 258 SUPERFAMILY SSF52266 5 196 8.99E-34 T 14-10-2018 MB46_16820 e7a6c0a29bccd9c58a84d5d3784d79b8 258 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 9 183 4.4E-20 T 14-10-2018 IPR013830 SGNH hydrolase-type esterase domain MB46_16820 e7a6c0a29bccd9c58a84d5d3784d79b8 258 Gene3D G3DSA:3.40.50.1110 1 197 2.1E-27 T 14-10-2018 IPR036514 SGNH hydrolase superfamily MB46_13685 d7b709ab454418b411101c712ddfe433 334 Pfam PF06013 Proteins of 100 residues with WXG 7 87 2.0E-8 T 14-10-2018 IPR010310 Type VII secretion system ESAT-6-like MB46_13685 d7b709ab454418b411101c712ddfe433 334 SUPERFAMILY SSF140453 4 88 5.49E-8 T 14-10-2018 IPR036689 ESAT-6-like superfamily MB46_13685 d7b709ab454418b411101c712ddfe433 334 Gene3D G3DSA:1.10.287.1060 1 94 1.0E-12 T 14-10-2018 MB46_02290 5bb44f59c9c814d045170f783cd62800 111 Pfam PF01022 Bacterial regulatory protein, arsR family 13 56 2.7E-10 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MB46_02290 5bb44f59c9c814d045170f783cd62800 111 SUPERFAMILY SSF46785 3 99 6.82E-24 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_02290 5bb44f59c9c814d045170f783cd62800 111 Gene3D G3DSA:1.10.10.10 4 104 6.4E-27 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_02290 5bb44f59c9c814d045170f783cd62800 111 SMART SM00418 5 82 1.3E-20 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MB46_02290 5bb44f59c9c814d045170f783cd62800 111 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 7 22 7.8E-10 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MB46_02290 5bb44f59c9c814d045170f783cd62800 111 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 54 69 7.8E-10 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MB46_02290 5bb44f59c9c814d045170f783cd62800 111 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 39 54 7.8E-10 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MB46_19065 22c3ee2b0fe70899aeb541d10dbeb73e 160 Pfam PF02559 CarD-like/TRCF domain 3 111 8.5E-18 T 14-10-2018 IPR003711 CarD-like/TRCF domain MB46_19065 22c3ee2b0fe70899aeb541d10dbeb73e 160 SMART SM01058 2 112 3.4E-31 T 14-10-2018 IPR003711 CarD-like/TRCF domain MB46_19065 22c3ee2b0fe70899aeb541d10dbeb73e 160 Gene3D G3DSA:2.30.30.840 1 60 1.5E-23 T 14-10-2018 MB46_19065 22c3ee2b0fe70899aeb541d10dbeb73e 160 Gene3D G3DSA:1.20.58.1290 61 160 1.4E-36 T 14-10-2018 MB46_19065 22c3ee2b0fe70899aeb541d10dbeb73e 160 SUPERFAMILY SSF141259 3 66 2.35E-13 T 14-10-2018 IPR036101 CarD-like/TRCF domain superfamily MB46_17645 adecda3693b072cdc6606a3ef68e7a22 483 Gene3D G3DSA:3.40.309.10 229 414 4.1E-189 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 MB46_17645 adecda3693b072cdc6606a3ef68e7a22 483 SUPERFAMILY SSF53720 5 476 5.11E-77 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 MB46_17645 adecda3693b072cdc6606a3ef68e7a22 483 Pfam PF00171 Aldehyde dehydrogenase family 6 419 2.3E-37 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 MB46_17645 adecda3693b072cdc6606a3ef68e7a22 483 Gene3D G3DSA:3.40.605.10 8 478 4.1E-189 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 MB46_04230 b7376a81b2ec1a1702d1cca448c0dea8 430 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 42 86 5.1E-7 T 14-10-2018 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger MB46_04230 b7376a81b2ec1a1702d1cca448c0dea8 430 Pfam PF01610 Transposase 183 419 1.2E-49 T 14-10-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain MB46_11315 ad28964dd8600c8f8e2f34bac19e69e2 475 SUPERFAMILY SSF51261 316 475 6.28E-40 T 14-10-2018 IPR011055 Duplicated hybrid motif MB46_11315 ad28964dd8600c8f8e2f34bac19e69e2 475 Pfam PF01551 Peptidase family M23 370 471 4.2E-27 T 14-10-2018 IPR016047 Peptidase M23 MB46_11315 ad28964dd8600c8f8e2f34bac19e69e2 475 Gene3D G3DSA:2.70.70.10 327 475 2.6E-41 T 14-10-2018 IPR011055 Duplicated hybrid motif MB46_07885 6e252ed43f625be033694f25ef66338a 815 SUPERFAMILY SSF81660 319 415 3.92E-5 T 14-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 MB46_07885 6e252ed43f625be033694f25ef66338a 815 Gene3D G3DSA:2.70.150.20 100 205 1.4E-23 T 14-10-2018 MB46_07885 6e252ed43f625be033694f25ef66338a 815 Gene3D G3DSA:1.20.1110.10 206 338 1.1E-12 T 14-10-2018 MB46_07885 6e252ed43f625be033694f25ef66338a 815 Pfam PF00702 haloacid dehalogenase-like hydrolase 314 575 3.8E-27 T 14-10-2018 MB46_07885 6e252ed43f625be033694f25ef66338a 815 Pfam PF00122 E1-E2 ATPase 108 296 4.6E-37 T 14-10-2018 MB46_07885 6e252ed43f625be033694f25ef66338a 815 SUPERFAMILY SSF56784 315 664 2.06E-38 T 14-10-2018 IPR036412 HAD-like superfamily MB46_07885 6e252ed43f625be033694f25ef66338a 815 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 317 331 1.6E-24 T 14-10-2018 MB46_07885 6e252ed43f625be033694f25ef66338a 815 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 158 172 1.6E-24 T 14-10-2018 MB46_07885 6e252ed43f625be033694f25ef66338a 815 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 584 596 1.6E-24 T 14-10-2018 MB46_07885 6e252ed43f625be033694f25ef66338a 815 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 561 580 1.6E-24 T 14-10-2018 MB46_07885 6e252ed43f625be033694f25ef66338a 815 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 483 493 1.6E-24 T 14-10-2018 MB46_07885 6e252ed43f625be033694f25ef66338a 815 Gene3D G3DSA:3.40.50.1000 443 621 1.3E-39 T 14-10-2018 IPR023214 HAD superfamily MB46_07885 6e252ed43f625be033694f25ef66338a 815 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 319 325 - T 14-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 MB46_07885 6e252ed43f625be033694f25ef66338a 815 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 536 649 2.5E-25 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MB46_07885 6e252ed43f625be033694f25ef66338a 815 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 82 506 4.1E-39 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MB46_07885 6e252ed43f625be033694f25ef66338a 815 SUPERFAMILY SSF81653 111 203 1.31E-21 T 14-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 MB46_07885 6e252ed43f625be033694f25ef66338a 815 SUPERFAMILY SSF81665 19 804 6.8E-60 T 14-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 MB46_07885 6e252ed43f625be033694f25ef66338a 815 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 561 577 4.2E-6 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MB46_07885 6e252ed43f625be033694f25ef66338a 815 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 418 436 4.2E-6 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MB46_15010 7c836fab7ad2320ded1f625189afeb20 273 Hamap MF_00193 NH(3)-dependent NAD(+) synthetase [nadE]. 19 267 49.657 T 14-10-2018 IPR022926 NH(3)-dependent NAD(+) synthetase GO:0008795|GO:0009435 KEGG: 00760+6.3.1.5 MB46_15010 7c836fab7ad2320ded1f625189afeb20 273 TIGRFAM TIGR00552 nadE: NAD+ synthetase 18 273 1.6E-73 T 14-10-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 MB46_15010 7c836fab7ad2320ded1f625189afeb20 273 Pfam PF02540 NAD synthase 24 264 2.4E-70 T 14-10-2018 IPR022310 NAD/GMP synthase MB46_15010 7c836fab7ad2320ded1f625189afeb20 273 SUPERFAMILY SSF52402 4 272 1.6E-80 T 14-10-2018 MB46_15010 7c836fab7ad2320ded1f625189afeb20 273 Gene3D G3DSA:3.40.50.620 1 273 6.7E-85 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MB46_11640 e0921f537c263c4e754e1b8adc7161f7 657 SUPERFAMILY SSF158472 290 341 9.02E-9 T 14-10-2018 MB46_11640 e0921f537c263c4e754e1b8adc7161f7 657 PRINTS PR00344 Bacterial sensor protein C-terminal signature 536 554 1.7E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MB46_11640 e0921f537c263c4e754e1b8adc7161f7 657 PRINTS PR00344 Bacterial sensor protein C-terminal signature 519 529 1.7E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MB46_11640 e0921f537c263c4e754e1b8adc7161f7 657 PRINTS PR00344 Bacterial sensor protein C-terminal signature 501 515 1.7E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MB46_11640 e0921f537c263c4e754e1b8adc7161f7 657 PRINTS PR00344 Bacterial sensor protein C-terminal signature 560 573 1.7E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MB46_11640 e0921f537c263c4e754e1b8adc7161f7 657 Pfam PF00512 His Kinase A (phospho-acceptor) domain 350 417 1.8E-13 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MB46_11640 e0921f537c263c4e754e1b8adc7161f7 657 SUPERFAMILY SSF55874 407 574 2.36E-36 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MB46_11640 e0921f537c263c4e754e1b8adc7161f7 657 Pfam PF00672 HAMP domain 290 339 3.0E-9 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MB46_11640 e0921f537c263c4e754e1b8adc7161f7 657 Gene3D G3DSA:1.20.1480.50 256 344 6.2E-13 T 14-10-2018 MB46_11640 e0921f537c263c4e754e1b8adc7161f7 657 Gene3D G3DSA:3.30.565.10 423 579 5.6E-31 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MB46_11640 e0921f537c263c4e754e1b8adc7161f7 657 Gene3D G3DSA:1.10.287.130 345 422 1.8E-16 T 14-10-2018 MB46_11640 e0921f537c263c4e754e1b8adc7161f7 657 SMART SM00387 465 576 9.0E-29 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MB46_11640 e0921f537c263c4e754e1b8adc7161f7 657 SUPERFAMILY SSF47384 333 417 1.69E-15 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MB46_11640 e0921f537c263c4e754e1b8adc7161f7 657 SMART SM00388 350 417 2.3E-16 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MB46_11640 e0921f537c263c4e754e1b8adc7161f7 657 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 466 575 3.6E-19 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MB46_11640 e0921f537c263c4e754e1b8adc7161f7 657 SMART SM00304 290 342 7.7E-13 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MB46_15630 1cb5a2abbc6e92ffb1185ff20f630fbc 371 Gene3D G3DSA:3.40.50.10350 1 358 3.9E-114 T 14-10-2018 IPR018197 Glycerate kinase, restriction-enzyme-like fold MB46_15630 1cb5a2abbc6e92ffb1185ff20f630fbc 371 Gene3D G3DSA:3.90.1510.10 42 274 3.9E-114 T 14-10-2018 IPR018193 Glycerate kinase, flavodoxin-like fold GO:0008887|GO:0031388 MB46_15630 1cb5a2abbc6e92ffb1185ff20f630fbc 371 PIRSF PIRSF006078 1 370 1.7E-124 T 14-10-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 MB46_15630 1cb5a2abbc6e92ffb1185ff20f630fbc 371 TIGRFAM TIGR00045 TIGR00045: glycerate kinase 2 360 2.0E-108 T 14-10-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 MB46_15630 1cb5a2abbc6e92ffb1185ff20f630fbc 371 SUPERFAMILY SSF110738 1 366 2.48E-105 T 14-10-2018 IPR036129 Glycerate kinase superfamily GO:0008887|GO:0031388 MB46_15630 1cb5a2abbc6e92ffb1185ff20f630fbc 371 Pfam PF02595 Glycerate kinase family 3 365 7.4E-117 T 14-10-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 MB46_11125 d616e7640a08c7aabeb95758cbe00612 409 Pfam PF13378 Enolase C-terminal domain-like 200 384 7.2E-43 T 14-10-2018 IPR029065 Enolase C-terminal domain-like MB46_11125 d616e7640a08c7aabeb95758cbe00612 409 Gene3D G3DSA:3.30.390.10 6 406 3.1E-162 T 14-10-2018 IPR029017 Enolase-like, N-terminal MB46_11125 d616e7640a08c7aabeb95758cbe00612 409 SUPERFAMILY SSF51604 98 393 1.09E-72 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily MB46_11125 d616e7640a08c7aabeb95758cbe00612 409 SMART SM00922 129 264 5.6E-18 T 14-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal MB46_11125 d616e7640a08c7aabeb95758cbe00612 409 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 85 110 - T 14-10-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 MB46_11125 d616e7640a08c7aabeb95758cbe00612 409 Gene3D G3DSA:3.20.20.120 105 374 3.1E-162 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily MB46_11125 d616e7640a08c7aabeb95758cbe00612 409 SUPERFAMILY SSF54826 2 112 4.5E-34 T 14-10-2018 MB46_11125 d616e7640a08c7aabeb95758cbe00612 409 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 11 110 4.7E-33 T 14-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain MB46_18920 2995db0db8f1f09ad71113f51a025fce 223 SMART SM00345 7 66 2.2E-18 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MB46_18920 2995db0db8f1f09ad71113f51a025fce 223 Gene3D G3DSA:1.20.120.530 88 223 1.0E-30 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MB46_18920 2995db0db8f1f09ad71113f51a025fce 223 SUPERFAMILY SSF48008 88 222 1.44E-28 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MB46_18920 2995db0db8f1f09ad71113f51a025fce 223 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 56 2.8E-6 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MB46_18920 2995db0db8f1f09ad71113f51a025fce 223 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 26 40 2.8E-6 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MB46_18920 2995db0db8f1f09ad71113f51a025fce 223 SMART SM00895 92 214 6.5E-24 T 14-10-2018 IPR011711 GntR, C-terminal MB46_18920 2995db0db8f1f09ad71113f51a025fce 223 Gene3D G3DSA:1.10.10.10 2 70 4.6E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_18920 2995db0db8f1f09ad71113f51a025fce 223 SUPERFAMILY SSF46785 4 70 3.88E-17 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_18920 2995db0db8f1f09ad71113f51a025fce 223 Pfam PF00392 Bacterial regulatory proteins, gntR family 5 66 2.3E-18 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MB46_18920 2995db0db8f1f09ad71113f51a025fce 223 Pfam PF07729 FCD domain 92 212 6.6E-27 T 14-10-2018 IPR011711 GntR, C-terminal MB46_03040 5190b7ead24adf7c0afeabeef7a69c2d 512 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 17 488 1.6E-178 T 14-10-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 MB46_03040 5190b7ead24adf7c0afeabeef7a69c2d 512 Gene3D G3DSA:3.90.1300.10 6 495 4.6E-176 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 MB46_03040 5190b7ead24adf7c0afeabeef7a69c2d 512 Pfam PF01425 Amidase 27 477 1.6E-147 T 14-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 MB46_03040 5190b7ead24adf7c0afeabeef7a69c2d 512 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 14 489 87.507 T 14-10-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 MB46_03040 5190b7ead24adf7c0afeabeef7a69c2d 512 SUPERFAMILY SSF75304 5 489 6.02E-150 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 MB46_03040 5190b7ead24adf7c0afeabeef7a69c2d 512 ProSitePatterns PS00571 Amidases signature. 158 189 - T 14-10-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 MB46_13845 444eb460f9ab2627604b4f066254a8be 845 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 717 837 2.9E-16 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MB46_13845 444eb460f9ab2627604b4f066254a8be 845 Pfam PF13493 Domain of unknown function (DUF4118) 382 482 1.4E-21 T 14-10-2018 IPR025201 Sensor protein KdpD, transmembrane domain MB46_13845 444eb460f9ab2627604b4f066254a8be 845 SUPERFAMILY SSF52402 233 358 9.57E-10 T 14-10-2018 MB46_13845 444eb460f9ab2627604b4f066254a8be 845 SMART SM00388 608 676 2.4E-14 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MB46_13845 444eb460f9ab2627604b4f066254a8be 845 Gene3D G3DSA:1.10.287.130 599 675 9.1E-15 T 14-10-2018 MB46_13845 444eb460f9ab2627604b4f066254a8be 845 Pfam PF00512 His Kinase A (phospho-acceptor) domain 611 675 2.2E-13 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MB46_13845 444eb460f9ab2627604b4f066254a8be 845 Gene3D G3DSA:3.40.50.300 1 210 2.0E-92 T 14-10-2018 MB46_13845 444eb460f9ab2627604b4f066254a8be 845 SUPERFAMILY SSF47384 598 675 5.69E-15 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MB46_13845 444eb460f9ab2627604b4f066254a8be 845 Gene3D G3DSA:3.30.565.10 688 840 1.2E-24 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MB46_13845 444eb460f9ab2627604b4f066254a8be 845 Gene3D G3DSA:1.20.120.620 373 475 6.4E-16 T 14-10-2018 IPR038318 KdpD, transmembrane domain superfamily MB46_13845 444eb460f9ab2627604b4f066254a8be 845 Pfam PF02702 Osmosensitive K+ channel His kinase sensor domain 3 211 4.1E-91 T 14-10-2018 IPR003852 Signal transduction histidine kinase, osmosensitive K+ channel sensor, N-terminal GO:0000155|GO:0000160|GO:0004673|GO:0016020 MB46_13845 444eb460f9ab2627604b4f066254a8be 845 Pfam PF00582 Universal stress protein family 231 347 1.2E-7 T 14-10-2018 IPR006016 UspA MB46_13845 444eb460f9ab2627604b4f066254a8be 845 PRINTS PR00344 Bacterial sensor protein C-terminal signature 822 835 1.1E-9 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MB46_13845 444eb460f9ab2627604b4f066254a8be 845 PRINTS PR00344 Bacterial sensor protein C-terminal signature 798 816 1.1E-9 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MB46_13845 444eb460f9ab2627604b4f066254a8be 845 PRINTS PR00344 Bacterial sensor protein C-terminal signature 761 775 1.1E-9 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MB46_13845 444eb460f9ab2627604b4f066254a8be 845 PRINTS PR00344 Bacterial sensor protein C-terminal signature 779 789 1.1E-9 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MB46_13845 444eb460f9ab2627604b4f066254a8be 845 Gene3D G3DSA:3.40.50.620 218 355 2.4E-7 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MB46_13845 444eb460f9ab2627604b4f066254a8be 845 SMART SM00387 716 838 7.8E-24 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MB46_13845 444eb460f9ab2627604b4f066254a8be 845 SUPERFAMILY SSF55874 666 836 5.37E-28 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MB46_03750 46ff81a72814d514b9e38bc4dc5b64a2 323 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 1 322 25.287 T 14-10-2018 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 MB46_03750 46ff81a72814d514b9e38bc4dc5b64a2 323 SUPERFAMILY SSF54814 177 254 1.53E-26 T 14-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 MB46_03750 46ff81a72814d514b9e38bc4dc5b64a2 323 Pfam PF13184 NusA-like KH domain 207 275 4.7E-25 T 14-10-2018 IPR025249 KH domain, NusA-like GO:0003723 MB46_03750 46ff81a72814d514b9e38bc4dc5b64a2 323 Gene3D G3DSA:3.30.300.20 176 254 8.9E-31 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta MB46_03750 46ff81a72814d514b9e38bc4dc5b64a2 323 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 73 319 8.5E-98 T 14-10-2018 IPR010213 Transcription termination factor NusA GO:0003723 MB46_03750 46ff81a72814d514b9e38bc4dc5b64a2 323 SMART SM00316 110 175 0.0017 T 14-10-2018 IPR022967 RNA-binding domain, S1 MB46_03750 46ff81a72814d514b9e38bc4dc5b64a2 323 SUPERFAMILY SSF69705 2 99 4.05E-28 T 14-10-2018 IPR036555 NusA, N-terminal domain superfamily GO:0003700|GO:0031554 MB46_03750 46ff81a72814d514b9e38bc4dc5b64a2 323 Gene3D G3DSA:3.30.1480.10 1 99 1.1E-33 T 14-10-2018 IPR036555 NusA, N-terminal domain superfamily GO:0003700|GO:0031554 MB46_03750 46ff81a72814d514b9e38bc4dc5b64a2 323 Gene3D G3DSA:2.40.50.140 105 175 1.1E-25 T 14-10-2018 MB46_03750 46ff81a72814d514b9e38bc4dc5b64a2 323 SUPERFAMILY SSF54814 256 319 5.49E-17 T 14-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 MB46_03750 46ff81a72814d514b9e38bc4dc5b64a2 323 Pfam PF08529 NusA N-terminal domain 6 59 2.3E-8 T 14-10-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 MB46_03750 46ff81a72814d514b9e38bc4dc5b64a2 323 Pfam PF08529 NusA N-terminal domain 66 100 9.4E-7 T 14-10-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 MB46_03750 46ff81a72814d514b9e38bc4dc5b64a2 323 Gene3D G3DSA:3.30.300.20 255 322 5.2E-29 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta MB46_03750 46ff81a72814d514b9e38bc4dc5b64a2 323 SUPERFAMILY SSF50249 109 176 8.38E-15 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold MB46_16125 80f19afa15f6c593b44438c99825504a 697 SUPERFAMILY SSF55874 35 240 8.51E-68 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MB46_16125 80f19afa15f6c593b44438c99825504a 697 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 33 697 86.676 T 14-10-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MB46_16125 80f19afa15f6c593b44438c99825504a 697 Gene3D G3DSA:3.40.50.670 455 697 2.7E-95 T 14-10-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MB46_16125 80f19afa15f6c593b44438c99825504a 697 Gene3D G3DSA:3.30.230.10 272 454 1.3E-70 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MB46_16125 80f19afa15f6c593b44438c99825504a 697 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 36 697 4.8E-282 T 14-10-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MB46_16125 80f19afa15f6c593b44438c99825504a 697 Gene3D G3DSA:3.30.565.10 33 244 2.1E-81 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MB46_16125 80f19afa15f6c593b44438c99825504a 697 ProSitePatterns PS00177 DNA topoisomerase II signature. 479 487 - T 14-10-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MB46_16125 80f19afa15f6c593b44438c99825504a 697 Pfam PF01751 Toprim domain 476 586 2.6E-14 T 14-10-2018 IPR006171 TOPRIM domain MB46_16125 80f19afa15f6c593b44438c99825504a 697 PRINTS PR00418 DNA topoisomerase II family signature 543 559 3.2E-66 T 14-10-2018 MB46_16125 80f19afa15f6c593b44438c99825504a 697 PRINTS PR00418 DNA topoisomerase II family signature 629 645 3.2E-66 T 14-10-2018 MB46_16125 80f19afa15f6c593b44438c99825504a 697 PRINTS PR00418 DNA topoisomerase II family signature 143 157 3.2E-66 T 14-10-2018 MB46_16125 80f19afa15f6c593b44438c99825504a 697 PRINTS PR00418 DNA topoisomerase II family signature 561 578 3.2E-66 T 14-10-2018 MB46_16125 80f19afa15f6c593b44438c99825504a 697 PRINTS PR00418 DNA topoisomerase II family signature 100 113 3.2E-66 T 14-10-2018 MB46_16125 80f19afa15f6c593b44438c99825504a 697 PRINTS PR00418 DNA topoisomerase II family signature 581 593 3.2E-66 T 14-10-2018 MB46_16125 80f19afa15f6c593b44438c99825504a 697 PRINTS PR00418 DNA topoisomerase II family signature 477 491 3.2E-66 T 14-10-2018 MB46_16125 80f19afa15f6c593b44438c99825504a 697 PRINTS PR00418 DNA topoisomerase II family signature 325 338 3.2E-66 T 14-10-2018 MB46_16125 80f19afa15f6c593b44438c99825504a 697 PRINTS PR00418 DNA topoisomerase II family signature 65 80 3.2E-66 T 14-10-2018 MB46_16125 80f19afa15f6c593b44438c99825504a 697 SMART SM00433 65 690 0.0 T 14-10-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MB46_16125 80f19afa15f6c593b44438c99825504a 697 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 628 686 4.9E-28 T 14-10-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 MB46_16125 80f19afa15f6c593b44438c99825504a 697 SMART SM00387 61 206 1.7E-24 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MB46_16125 80f19afa15f6c593b44438c99825504a 697 SUPERFAMILY SSF56719 451 692 1.67E-81 T 14-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 MB46_16125 80f19afa15f6c593b44438c99825504a 697 PRINTS PR01159 DNA gyrase subunit B signature 369 385 1.3E-68 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MB46_16125 80f19afa15f6c593b44438c99825504a 697 PRINTS PR01159 DNA gyrase subunit B signature 36 46 1.3E-68 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MB46_16125 80f19afa15f6c593b44438c99825504a 697 PRINTS PR01159 DNA gyrase subunit B signature 226 239 1.3E-68 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MB46_16125 80f19afa15f6c593b44438c99825504a 697 PRINTS PR01159 DNA gyrase subunit B signature 211 226 1.3E-68 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MB46_16125 80f19afa15f6c593b44438c99825504a 697 PRINTS PR01159 DNA gyrase subunit B signature 417 431 1.3E-68 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MB46_16125 80f19afa15f6c593b44438c99825504a 697 PRINTS PR01159 DNA gyrase subunit B signature 299 317 1.3E-68 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MB46_16125 80f19afa15f6c593b44438c99825504a 697 PRINTS PR01159 DNA gyrase subunit B signature 527 536 1.3E-68 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MB46_16125 80f19afa15f6c593b44438c99825504a 697 PRINTS PR01159 DNA gyrase subunit B signature 650 662 1.3E-68 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MB46_16125 80f19afa15f6c593b44438c99825504a 697 PRINTS PR01159 DNA gyrase subunit B signature 273 295 1.3E-68 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MB46_16125 80f19afa15f6c593b44438c99825504a 697 PRINTS PR01159 DNA gyrase subunit B signature 431 451 1.3E-68 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MB46_16125 80f19afa15f6c593b44438c99825504a 697 PRINTS PR01159 DNA gyrase subunit B signature 666 682 1.3E-68 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MB46_16125 80f19afa15f6c593b44438c99825504a 697 SUPERFAMILY SSF54211 274 447 1.84E-54 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MB46_16125 80f19afa15f6c593b44438c99825504a 697 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 63 205 1.2E-20 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MB46_16125 80f19afa15f6c593b44438c99825504a 697 Pfam PF00204 DNA gyrase B 274 447 1.0E-61 T 14-10-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MB46_11575 316a9b4616d8c6d66a9bd45f7a6708ea 492 SUPERFAMILY SSF55785 178 286 4.19E-8 T 14-10-2018 IPR035965 PAS domain superfamily MB46_11575 316a9b4616d8c6d66a9bd45f7a6708ea 492 Pfam PF07568 Histidine kinase 295 359 4.5E-20 T 14-10-2018 IPR011495 Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain MB46_11575 316a9b4616d8c6d66a9bd45f7a6708ea 492 Pfam PF12282 Signal transduction histidine kinase 5 148 2.7E-48 T 14-10-2018 IPR022066 Signal transduction histidine kinase, N-terminal MB46_11575 316a9b4616d8c6d66a9bd45f7a6708ea 492 PRINTS PR00344 Bacterial sensor protein C-terminal signature 474 487 9.4E-5 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MB46_11575 316a9b4616d8c6d66a9bd45f7a6708ea 492 PRINTS PR00344 Bacterial sensor protein C-terminal signature 449 467 9.4E-5 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MB46_11575 316a9b4616d8c6d66a9bd45f7a6708ea 492 PRINTS PR00344 Bacterial sensor protein C-terminal signature 433 447 9.4E-5 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MB46_11575 316a9b4616d8c6d66a9bd45f7a6708ea 492 Gene3D G3DSA:3.30.450.280 1 133 2.6E-42 T 14-10-2018 IPR038424 Signal transduction histidine kinase, N-terminal domain superfamily MB46_11575 316a9b4616d8c6d66a9bd45f7a6708ea 492 SMART SM00387 389 490 1.9E-7 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MB46_11575 316a9b4616d8c6d66a9bd45f7a6708ea 492 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 393 486 2.5E-10 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MB46_11575 316a9b4616d8c6d66a9bd45f7a6708ea 492 SUPERFAMILY SSF55874 352 485 7.99E-17 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MB46_11575 316a9b4616d8c6d66a9bd45f7a6708ea 492 Gene3D G3DSA:3.30.565.10 355 488 2.1E-22 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MB46_11575 316a9b4616d8c6d66a9bd45f7a6708ea 492 Gene3D G3DSA:3.30.450.20 134 281 4.0E-45 T 14-10-2018 MB46_11575 316a9b4616d8c6d66a9bd45f7a6708ea 492 Pfam PF08448 PAS fold 176 281 7.3E-9 T 14-10-2018 IPR013656 PAS fold-4 MB46_04265 a8464f3d1978d492db8f1e1be44075d7 575 Gene3D G3DSA:3.40.50.300 278 569 3.8E-54 T 14-10-2018 MB46_04265 a8464f3d1978d492db8f1e1be44075d7 575 TIGRFAM TIGR00634 recN: DNA repair protein RecN 1 568 3.9E-156 T 14-10-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 MB46_04265 a8464f3d1978d492db8f1e1be44075d7 575 Gene3D G3DSA:3.40.50.300 1 209 2.4E-32 T 14-10-2018 MB46_04265 a8464f3d1978d492db8f1e1be44075d7 575 PIRSF PIRSF003128 1 573 4.5E-151 T 14-10-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 MB46_04265 a8464f3d1978d492db8f1e1be44075d7 575 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 520 2.9E-14 T 14-10-2018 IPR003395 RecF/RecN/SMC, N-terminal MB46_04265 a8464f3d1978d492db8f1e1be44075d7 575 SUPERFAMILY SSF52540 1 223 6.5E-50 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_04265 a8464f3d1978d492db8f1e1be44075d7 575 SUPERFAMILY SSF52540 3 519 6.97E-22 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_09865 cf54e779d840de80ee893d59927f0285 274 SUPERFAMILY SSF46689 225 269 8.06E-6 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MB46_09865 cf54e779d840de80ee893d59927f0285 274 SMART SM00342 189 271 1.5E-19 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MB46_09865 cf54e779d840de80ee893d59927f0285 274 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 223 267 - T 14-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 MB46_09865 cf54e779d840de80ee893d59927f0285 274 Pfam PF02311 AraC-like ligand binding domain 52 104 1.7E-6 T 14-10-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 MB46_09865 cf54e779d840de80ee893d59927f0285 274 Gene3D G3DSA:1.10.10.60 174 273 9.5E-19 T 14-10-2018 MB46_09865 cf54e779d840de80ee893d59927f0285 274 Gene3D G3DSA:2.60.120.10 26 117 7.0E-8 T 14-10-2018 IPR014710 RmlC-like jelly roll fold MB46_09865 cf54e779d840de80ee893d59927f0285 274 SUPERFAMILY SSF51182 12 203 3.02E-13 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily MB46_09865 cf54e779d840de80ee893d59927f0285 274 Pfam PF12833 Helix-turn-helix domain 195 268 1.4E-18 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MB46_13790 dbec7793b325d440eaf2849fcda147d6 447 TIGRFAM TIGR03860 FMN_nitrolo: FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family 10 427 1.7E-176 T 14-10-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 MB46_13790 dbec7793b325d440eaf2849fcda147d6 447 Pfam PF00296 Luciferase-like monooxygenase 22 383 1.5E-63 T 14-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MB46_13790 dbec7793b325d440eaf2849fcda147d6 447 SUPERFAMILY SSF51679 5 433 4.58E-135 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 MB46_13790 dbec7793b325d440eaf2849fcda147d6 447 PIRSF PIRSF000337 4 442 1.5E-163 T 14-10-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 MB46_13790 dbec7793b325d440eaf2849fcda147d6 447 Gene3D G3DSA:3.20.20.30 1 446 6.3E-162 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 MB46_11000 26744cc817d3bc38369405bab9b44276 167 SMART SM00347 43 146 2.9E-17 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MB46_11000 26744cc817d3bc38369405bab9b44276 167 PRINTS PR00598 Bacterial regulatory protein MarR family signature 87 102 6.8E-7 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MB46_11000 26744cc817d3bc38369405bab9b44276 167 PRINTS PR00598 Bacterial regulatory protein MarR family signature 136 156 6.8E-7 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MB46_11000 26744cc817d3bc38369405bab9b44276 167 PRINTS PR00598 Bacterial regulatory protein MarR family signature 106 122 6.8E-7 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MB46_11000 26744cc817d3bc38369405bab9b44276 167 Pfam PF12802 MarR family 49 110 3.2E-10 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MB46_11000 26744cc817d3bc38369405bab9b44276 167 Gene3D G3DSA:1.10.10.10 1 160 1.7E-36 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_11000 26744cc817d3bc38369405bab9b44276 167 SUPERFAMILY SSF46785 10 159 1.53E-32 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_02080 2cd453fa62285a44f9faf47468690304 440 Gene3D G3DSA:2.60.40.10 282 356 6.5E-7 T 14-10-2018 IPR013783 Immunoglobulin-like fold MB46_02080 2cd453fa62285a44f9faf47468690304 440 Gene3D G3DSA:2.60.40.10 12 92 1.7E-5 T 14-10-2018 IPR013783 Immunoglobulin-like fold MB46_07635 e163feed706a14e17a9af1f15fedcb95 481 SUPERFAMILY SSF53686 42 432 7.6E-140 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme MB46_07635 e163feed706a14e17a9af1f15fedcb95 481 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 44 430 1.9E-182 T 14-10-2018 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 MB46_07635 e163feed706a14e17a9af1f15fedcb95 481 Gene3D G3DSA:3.40.50.1100 46 242 1.3E-181 T 14-10-2018 MB46_07635 e163feed706a14e17a9af1f15fedcb95 481 PIRSF PIRSF001413 30 437 1.7E-157 T 14-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 MB46_07635 e163feed706a14e17a9af1f15fedcb95 481 Gene3D G3DSA:3.40.50.1100 90 426 1.3E-181 T 14-10-2018 MB46_07635 e163feed706a14e17a9af1f15fedcb95 481 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 34 433 50.451 T 14-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 MB46_07635 e163feed706a14e17a9af1f15fedcb95 481 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 117 131 - T 14-10-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 MB46_07635 e163feed706a14e17a9af1f15fedcb95 481 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 90 416 1.8E-46 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme MB46_03005 fa562d8d0a3ab67b91c3f21f8f7088b5 380 Gene3D G3DSA:1.10.10.10 1 64 7.0E-12 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_03005 fa562d8d0a3ab67b91c3f21f8f7088b5 380 Gene3D G3DSA:3.30.420.40 67 201 3.1E-26 T 14-10-2018 MB46_03005 fa562d8d0a3ab67b91c3f21f8f7088b5 380 Gene3D G3DSA:3.30.420.40 202 344 2.3E-25 T 14-10-2018 MB46_03005 fa562d8d0a3ab67b91c3f21f8f7088b5 380 SUPERFAMILY SSF53067 69 370 2.22E-37 T 14-10-2018 MB46_03005 fa562d8d0a3ab67b91c3f21f8f7088b5 380 SUPERFAMILY SSF46785 3 64 1.26E-7 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_03005 fa562d8d0a3ab67b91c3f21f8f7088b5 380 Pfam PF00480 ROK family 72 366 7.5E-31 T 14-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 MB46_13990 d7caac782060da788179e4816536e2e4 252 Gene3D G3DSA:3.40.50.720 4 251 4.5E-71 T 14-10-2018 MB46_13990 d7caac782060da788179e4816536e2e4 252 SUPERFAMILY SSF51735 11 250 2.79E-74 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_13990 d7caac782060da788179e4816536e2e4 252 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 19 250 4.1E-60 T 14-10-2018 MB46_13990 d7caac782060da788179e4816536e2e4 252 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MB46_13990 d7caac782060da788179e4816536e2e4 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 4.5E-43 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_13990 d7caac782060da788179e4816536e2e4 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 4.5E-43 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_13990 d7caac782060da788179e4816536e2e4 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 213 233 4.5E-43 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_13990 d7caac782060da788179e4816536e2e4 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 14 31 4.5E-43 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_13990 d7caac782060da788179e4816536e2e4 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 4.5E-43 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_13990 d7caac782060da788179e4816536e2e4 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 4.5E-43 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_13990 d7caac782060da788179e4816536e2e4 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 7.6E-13 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_13990 d7caac782060da788179e4816536e2e4 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 7.6E-13 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_13990 d7caac782060da788179e4816536e2e4 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 7.6E-13 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_09125 099aa06631538333f20570bc9fec2124 163 SUPERFAMILY SSF54637 6 140 9.64E-27 T 14-10-2018 IPR029069 HotDog domain superfamily MB46_09125 099aa06631538333f20570bc9fec2124 163 Pfam PF13279 Thioesterase-like superfamily 12 126 7.6E-8 T 14-10-2018 MB46_09125 099aa06631538333f20570bc9fec2124 163 Gene3D G3DSA:3.10.129.10 6 143 1.9E-34 T 14-10-2018 MB46_09500 b9ff34ef9e1cd947be49fec86dc33586 311 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 15 311 55.067 T 14-10-2018 IPR023009 Tyrosine recombinase XerC/XerD MB46_09500 b9ff34ef9e1cd947be49fec86dc33586 311 Gene3D G3DSA:1.10.150.130 13 119 2.5E-20 T 14-10-2018 IPR010998 Integrase/recombinase, N-terminal MB46_09500 b9ff34ef9e1cd947be49fec86dc33586 311 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 18 99 4.8E-20 T 14-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 MB46_09500 b9ff34ef9e1cd947be49fec86dc33586 311 SUPERFAMILY SSF56349 17 302 1.41E-50 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MB46_09500 b9ff34ef9e1cd947be49fec86dc33586 311 Pfam PF00589 Phage integrase family 122 296 1.1E-42 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MB46_09500 b9ff34ef9e1cd947be49fec86dc33586 311 Gene3D G3DSA:1.10.443.10 122 305 6.3E-58 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 MB46_10755 e14c21563f356d409816aacb57e5b4e2 205 SUPERFAMILY SSF52499 3 203 3.92E-46 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 MB46_10755 e14c21563f356d409816aacb57e5b4e2 205 Gene3D G3DSA:3.40.50.850 2 205 5.1E-62 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 MB46_10755 e14c21563f356d409816aacb57e5b4e2 205 Pfam PF00857 Isochorismatase family 4 203 2.4E-31 T 14-10-2018 IPR000868 Isochorismatase-like GO:0003824 MB46_11250 b7c07cf104a8908be6877eb5338da96e 271 SUPERFAMILY SSF56655 8 266 3.01E-75 T 14-10-2018 MB46_11250 b7c07cf104a8908be6877eb5338da96e 271 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 85 98 - T 14-10-2018 IPR020583 Inositol monophosphatase, metal-binding site MB46_11250 b7c07cf104a8908be6877eb5338da96e 271 Gene3D G3DSA:3.40.190.80 150 263 6.9E-23 T 14-10-2018 MB46_11250 b7c07cf104a8908be6877eb5338da96e 271 TIGRFAM TIGR02067 his_9_HisN: histidinol-phosphatase 12 263 1.1E-91 T 14-10-2018 IPR011809 Histidinol-phosphate phosphatase, putative, inositol monophosphatase GO:0004401 KEGG: 00340+3.1.3.15 MB46_11250 b7c07cf104a8908be6877eb5338da96e 271 PRINTS PR00377 Inositol monophosphatase superfamily signature 44 64 8.8E-20 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MB46_11250 b7c07cf104a8908be6877eb5338da96e 271 PRINTS PR00377 Inositol monophosphatase superfamily signature 139 162 8.8E-20 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MB46_11250 b7c07cf104a8908be6877eb5338da96e 271 PRINTS PR00377 Inositol monophosphatase superfamily signature 85 101 8.8E-20 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MB46_11250 b7c07cf104a8908be6877eb5338da96e 271 PRINTS PR00377 Inositol monophosphatase superfamily signature 214 238 8.8E-20 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MB46_11250 b7c07cf104a8908be6877eb5338da96e 271 PRINTS PR00377 Inositol monophosphatase superfamily signature 66 82 8.8E-20 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MB46_11250 b7c07cf104a8908be6877eb5338da96e 271 Pfam PF00459 Inositol monophosphatase family 18 253 1.9E-48 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MB46_11250 b7c07cf104a8908be6877eb5338da96e 271 Gene3D G3DSA:3.30.540.10 2 142 2.1E-40 T 14-10-2018 MB46_11525 e40bd6183d14010ba73e4b9ceca18d1a 367 Pfam PF00534 Glycosyl transferases group 1 181 328 2.9E-20 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 MB46_11525 e40bd6183d14010ba73e4b9ceca18d1a 367 Gene3D G3DSA:3.40.50.2000 187 334 4.4E-26 T 14-10-2018 MB46_11525 e40bd6183d14010ba73e4b9ceca18d1a 367 Pfam PF13439 Glycosyltransferase Family 4 29 173 5.6E-13 T 14-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 MB46_11525 e40bd6183d14010ba73e4b9ceca18d1a 367 SUPERFAMILY SSF53756 2 331 4.5E-49 T 14-10-2018 MB46_11525 e40bd6183d14010ba73e4b9ceca18d1a 367 Gene3D G3DSA:3.40.50.2000 2 186 5.1E-17 T 14-10-2018 MB46_04765 fcbb0c7c7cfd095183cecb20a0ded833 130 Pfam PF11255 Protein of unknown function (DUF3054) 17 119 1.2E-28 T 14-10-2018 IPR021414 Protein of unknown function DUF3054 MB46_12600 b9e1fe242fc4bfc219fbff95ef757a2a 214 Gene3D G3DSA:3.40.430.10 2 210 2.2E-33 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 MB46_12600 b9e1fe242fc4bfc219fbff95ef757a2a 214 Pfam PF01872 RibD C-terminal domain 9 184 7.1E-13 T 14-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 MB46_12600 b9e1fe242fc4bfc219fbff95ef757a2a 214 SUPERFAMILY SSF53597 55 192 1.24E-19 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 MB46_18930 0c531b03bd26755ed131086264e075ee 705 Gene3D G3DSA:3.40.50.1820 15 662 2.1E-124 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_18930 0c531b03bd26755ed131086264e075ee 705 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 475 493 4.1E-42 T 14-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 MB46_18930 0c531b03bd26755ed131086264e075ee 705 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 634 656 4.1E-42 T 14-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 MB46_18930 0c531b03bd26755ed131086264e075ee 705 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 530 549 4.1E-42 T 14-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 MB46_18930 0c531b03bd26755ed131086264e075ee 705 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 560 580 4.1E-42 T 14-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 MB46_18930 0c531b03bd26755ed131086264e075ee 705 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 615 630 4.1E-42 T 14-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 MB46_18930 0c531b03bd26755ed131086264e075ee 705 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 502 526 4.1E-42 T 14-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 MB46_18930 0c531b03bd26755ed131086264e075ee 705 SUPERFAMILY SSF53474 443 701 6.06E-49 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_18930 0c531b03bd26755ed131086264e075ee 705 Pfam PF02897 Prolyl oligopeptidase, N-terminal beta-propeller domain 15 218 2.3E-16 T 14-10-2018 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 MB46_18930 0c531b03bd26755ed131086264e075ee 705 Pfam PF00326 Prolyl oligopeptidase family 499 703 1.5E-43 T 14-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 MB46_18930 0c531b03bd26755ed131086264e075ee 705 SUPERFAMILY SSF50993 15 410 7.06E-38 T 14-10-2018 MB46_18930 0c531b03bd26755ed131086264e075ee 705 Gene3D G3DSA:2.130.10.120 64 435 2.1E-124 T 14-10-2018 MB46_05240 79d63e7b0c5696b62e5faa1cd4d10c6f 268 SUPERFAMILY SSF55315 3 105 1.01E-15 T 14-10-2018 IPR029064 50S ribosomal protein L30e-like MB46_05240 79d63e7b0c5696b62e5faa1cd4d10c6f 268 Gene3D G3DSA:3.40.1280.10 109 267 3.8E-47 T 14-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal MB46_05240 79d63e7b0c5696b62e5faa1cd4d10c6f 268 SUPERFAMILY SSF75217 114 265 3.2E-37 T 14-10-2018 IPR029028 Alpha/beta knot methyltransferases MB46_05240 79d63e7b0c5696b62e5faa1cd4d10c6f 268 Pfam PF00588 SpoU rRNA Methylase family 120 261 7.3E-32 T 14-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 MB46_10210 d3c92951e849b2bdf21990e7a8f3897a 389 Gene3D G3DSA:3.30.420.40 206 364 6.0E-75 T 14-10-2018 MB46_10210 d3c92951e849b2bdf21990e7a8f3897a 389 Gene3D G3DSA:3.30.420.40 87 374 6.0E-75 T 14-10-2018 MB46_10210 d3c92951e849b2bdf21990e7a8f3897a 389 SUPERFAMILY SSF53067 81 381 4.54E-54 T 14-10-2018 MB46_10210 d3c92951e849b2bdf21990e7a8f3897a 389 Pfam PF00480 ROK family 86 378 4.5E-53 T 14-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 MB46_10210 d3c92951e849b2bdf21990e7a8f3897a 389 SUPERFAMILY SSF46785 16 73 1.16E-10 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_10210 d3c92951e849b2bdf21990e7a8f3897a 389 Gene3D G3DSA:1.10.10.10 13 75 1.9E-12 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_10210 d3c92951e849b2bdf21990e7a8f3897a 389 Pfam PF13412 Winged helix-turn-helix DNA-binding 27 56 6.1E-5 T 14-10-2018 MB46_18020 eead9af55e02a5ea7c2102e390c627b7 312 SUPERFAMILY SSF52833 149 311 5.07E-25 T 14-10-2018 IPR036249 Thioredoxin-like superfamily MB46_18020 eead9af55e02a5ea7c2102e390c627b7 312 SMART SM00422 1 69 1.6E-18 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MB46_18020 eead9af55e02a5ea7c2102e390c627b7 312 Gene3D G3DSA:3.40.30.10 153 312 1.6E-22 T 14-10-2018 MB46_18020 eead9af55e02a5ea7c2102e390c627b7 312 Pfam PF13411 MerR HTH family regulatory protein 1 60 4.1E-14 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MB46_18020 eead9af55e02a5ea7c2102e390c627b7 312 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 5.3E-6 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MB46_18020 eead9af55e02a5ea7c2102e390c627b7 312 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 5.3E-6 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MB46_18020 eead9af55e02a5ea7c2102e390c627b7 312 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 5.3E-6 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MB46_18020 eead9af55e02a5ea7c2102e390c627b7 312 Gene3D G3DSA:1.10.1660.10 1 124 2.8E-24 T 14-10-2018 MB46_18020 eead9af55e02a5ea7c2102e390c627b7 312 SUPERFAMILY SSF46955 1 112 4.03E-21 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily MB46_18020 eead9af55e02a5ea7c2102e390c627b7 312 Pfam PF08534 Redoxin 151 306 5.8E-17 T 14-10-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 MB46_12895 f1f0686a7b2f07b4d194ac9641a3761e 490 Gene3D G3DSA:3.50.50.60 3 333 7.2E-121 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_12895 f1f0686a7b2f07b4d194ac9641a3761e 490 Gene3D G3DSA:3.30.70.2450 173 259 7.2E-121 T 14-10-2018 MB46_12895 f1f0686a7b2f07b4d194ac9641a3761e 490 Gene3D G3DSA:3.40.30.120 381 475 1.2E-23 T 14-10-2018 MB46_12895 f1f0686a7b2f07b4d194ac9641a3761e 490 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 321 337 2.1E-43 T 14-10-2018 MB46_12895 f1f0686a7b2f07b4d194ac9641a3761e 490 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 144 159 2.1E-43 T 14-10-2018 MB46_12895 f1f0686a7b2f07b4d194ac9641a3761e 490 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 285 301 2.1E-43 T 14-10-2018 MB46_12895 f1f0686a7b2f07b4d194ac9641a3761e 490 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 303 321 2.1E-43 T 14-10-2018 MB46_12895 f1f0686a7b2f07b4d194ac9641a3761e 490 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 270 285 2.1E-43 T 14-10-2018 MB46_12895 f1f0686a7b2f07b4d194ac9641a3761e 490 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 2.1E-43 T 14-10-2018 MB46_12895 f1f0686a7b2f07b4d194ac9641a3761e 490 SUPERFAMILY SSF51905 2 353 4.75E-67 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_12895 f1f0686a7b2f07b4d194ac9641a3761e 490 Pfam PF01494 FAD binding domain 3 334 2.2E-86 T 14-10-2018 IPR002938 FAD-binding domain GO:0071949 MB46_14835 46a131eb1a3ddcb9db4484cb9cbd6ce5 292 PIRSF PIRSF000103 1 292 1.3E-79 T 14-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 MB46_14835 46a131eb1a3ddcb9db4484cb9cbd6ce5 292 SUPERFAMILY SSF51735 2 163 7.06E-46 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_14835 46a131eb1a3ddcb9db4484cb9cbd6ce5 292 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 3 162 7.6E-49 T 14-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 MB46_14835 46a131eb1a3ddcb9db4484cb9cbd6ce5 292 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 6 19 - T 14-10-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 MB46_14835 46a131eb1a3ddcb9db4484cb9cbd6ce5 292 TIGRFAM TIGR01505 tartro_sem_red: 2-hydroxy-3-oxopropionate reductase 4 290 1.9E-110 T 14-10-2018 IPR006398 2-hydroxy-3-oxopropionate reductase GO:0008679|GO:0046487|GO:0055114 KEGG: 00630+1.1.1.60 MB46_14835 46a131eb1a3ddcb9db4484cb9cbd6ce5 292 Gene3D G3DSA:3.40.50.720 1 162 3.7E-53 T 14-10-2018 MB46_14835 46a131eb1a3ddcb9db4484cb9cbd6ce5 292 SUPERFAMILY SSF48179 163 290 4.31E-36 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MB46_14835 46a131eb1a3ddcb9db4484cb9cbd6ce5 292 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 165 283 9.9E-38 T 14-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 MB46_14835 46a131eb1a3ddcb9db4484cb9cbd6ce5 292 Gene3D G3DSA:1.10.1040.10 163 291 6.3E-39 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MB46_17630 4d0767ccf5a7b9c7cfab9b769b589c04 311 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 241 1.0E-30 T 14-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 MB46_17630 4d0767ccf5a7b9c7cfab9b769b589c04 311 SUPERFAMILY SSF51735 1 301 2.25E-51 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_17630 4d0767ccf5a7b9c7cfab9b769b589c04 311 Gene3D G3DSA:3.40.50.720 1 306 1.3E-50 T 14-10-2018 MB46_08120 9e8aba3cfb721fe6cf9799d82d9657c6 250 PIRSF PIRSF039085 8 250 8.1E-117 T 14-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 MB46_08120 9e8aba3cfb721fe6cf9799d82d9657c6 250 SMART SM00382 36 223 6.8E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_08120 9e8aba3cfb721fe6cf9799d82d9657c6 250 Gene3D G3DSA:3.40.50.300 11 250 1.2E-82 T 14-10-2018 MB46_08120 9e8aba3cfb721fe6cf9799d82d9657c6 250 SUPERFAMILY SSF52540 12 245 3.34E-79 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_08120 9e8aba3cfb721fe6cf9799d82d9657c6 250 Pfam PF00005 ABC transporter 27 175 6.2E-35 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_08120 9e8aba3cfb721fe6cf9799d82d9657c6 250 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_04375 6dfe45ae5282510f24d16885a19c47ad 506 Pfam PF03972 MmgE/PrpD family 21 476 4.6E-128 T 14-10-2018 IPR005656 MmgE/PrpD GO:0016829 MB46_04375 6dfe45ae5282510f24d16885a19c47ad 506 Gene3D G3DSA:1.10.4100.10 46 470 7.1E-69 T 14-10-2018 MB46_04375 6dfe45ae5282510f24d16885a19c47ad 506 Gene3D G3DSA:3.30.1330.120 286 435 7.1E-69 T 14-10-2018 MB46_04375 6dfe45ae5282510f24d16885a19c47ad 506 SUPERFAMILY SSF103378 19 487 5.36E-125 T 14-10-2018 IPR036148 MmgE/PrpD superfamily GO:0016829 MB46_07680 05ac35667e14db6966cd54ee01f87419 87 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 1 87 17.981 T 14-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 MB46_07680 05ac35667e14db6966cd54ee01f87419 87 Gene3D G3DSA:1.10.287.1080 1 87 1.1E-21 T 14-10-2018 MB46_07680 05ac35667e14db6966cd54ee01f87419 87 SUPERFAMILY SSF101386 2 87 8.07E-21 T 14-10-2018 MB46_07680 05ac35667e14db6966cd54ee01f87419 87 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 2 86 2.2E-8 T 14-10-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 MB46_07680 05ac35667e14db6966cd54ee01f87419 87 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 5 87 4.7E-23 T 14-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 MB46_11555 1ea67faccc80805bb80360725243b35d 394 TIGRFAM TIGR00031 UDP-GALP_mutase: UDP-galactopyranose mutase 4 377 8.5E-99 T 14-10-2018 IPR004379 UDP-galactopyranose mutase GO:0008767 KEGG: 00052+5.4.99.9|KEGG: 00520+5.4.99.9|MetaCyc: PWY-6397|MetaCyc: PWY-7328|MetaCyc: PWY-7622 MB46_11555 1ea67faccc80805bb80360725243b35d 394 Pfam PF13450 NAD(P)-binding Rossmann-like domain 7 76 4.7E-17 T 14-10-2018 MB46_11555 1ea67faccc80805bb80360725243b35d 394 Gene3D G3DSA:3.40.50.720 282 387 3.2E-16 T 14-10-2018 MB46_11555 1ea67faccc80805bb80360725243b35d 394 Gene3D G3DSA:3.40.50.720 1 98 1.2E-31 T 14-10-2018 MB46_11555 1ea67faccc80805bb80360725243b35d 394 SUPERFAMILY SSF54373 255 326 6.08E-22 T 14-10-2018 MB46_11555 1ea67faccc80805bb80360725243b35d 394 Pfam PF03275 UDP-galactopyranose mutase 151 359 2.6E-82 T 14-10-2018 IPR015899 UDP-galactopyranose mutase, C-terminal GO:0008767 KEGG: 00052+5.4.99.9|KEGG: 00520+5.4.99.9|MetaCyc: PWY-6397|MetaCyc: PWY-7328|MetaCyc: PWY-7622 MB46_11555 1ea67faccc80805bb80360725243b35d 394 SUPERFAMILY SSF51971 4 374 1.05E-44 T 14-10-2018 MB46_11555 1ea67faccc80805bb80360725243b35d 394 Gene3D G3DSA:3.40.50.720 153 267 1.4E-26 T 14-10-2018 MB46_10515 12a2bff735782e304eae5f5214fea11f 699 Pfam PF02720 Domain of unknown function (DUF222) 481 593 7.5E-9 T 14-10-2018 IPR003870 Domain of unknown function DUF222 MB46_10515 12a2bff735782e304eae5f5214fea11f 699 Pfam PF02720 Domain of unknown function (DUF222) 82 304 1.4E-15 T 14-10-2018 IPR003870 Domain of unknown function DUF222 MB46_10515 12a2bff735782e304eae5f5214fea11f 699 SMART SM00507 584 636 5.6E-10 T 14-10-2018 IPR003615 HNH nuclease MB46_10515 12a2bff735782e304eae5f5214fea11f 699 Pfam PF01844 HNH endonuclease 608 640 1.4E-6 T 14-10-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 MB46_12835 728be67f9a7293902deec0be8831cb70 319 Gene3D G3DSA:2.70.98.10 11 317 9.8E-69 T 14-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 MB46_12835 728be67f9a7293902deec0be8831cb70 319 Pfam PF01263 Aldose 1-epimerase 13 313 4.2E-41 T 14-10-2018 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 MB46_12835 728be67f9a7293902deec0be8831cb70 319 SUPERFAMILY SSF74650 12 316 1.88E-58 T 14-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 MB46_19015 6a35e5d91e98be7b4764382ddbfac4a1 216 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 10 205 3.7E-53 T 14-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 MB46_19015 6a35e5d91e98be7b4764382ddbfac4a1 216 Gene3D G3DSA:3.40.50.300 6 214 2.4E-65 T 14-10-2018 MB46_19015 6a35e5d91e98be7b4764382ddbfac4a1 216 Hamap MF_00165 Thymidylate kinase [tmk]. 11 213 29.715 T 14-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 MB46_19015 6a35e5d91e98be7b4764382ddbfac4a1 216 Pfam PF02223 Thymidylate kinase 15 205 2.4E-50 T 14-10-2018 IPR039430 Thymidylate kinase-like domain KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 MB46_19015 6a35e5d91e98be7b4764382ddbfac4a1 216 ProSitePatterns PS01331 Thymidylate kinase signature. 100 112 - T 14-10-2018 IPR018095 Thymidylate kinase, conserved site GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 MB46_19015 6a35e5d91e98be7b4764382ddbfac4a1 216 SUPERFAMILY SSF52540 9 209 3.88E-52 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_03215 bbe40369996de73fed575e8de56b0f38 217 Gene3D G3DSA:3.40.50.1820 1 212 7.3E-38 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_03215 bbe40369996de73fed575e8de56b0f38 217 Pfam PF02230 Phospholipase/Carboxylesterase 14 207 6.0E-13 T 14-10-2018 IPR003140 Phospholipase/carboxylesterase/thioesterase GO:0016787 MB46_03215 bbe40369996de73fed575e8de56b0f38 217 SUPERFAMILY SSF53474 7 206 1.32E-38 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_02915 bc784e86767c6b82c9fc00b779e73c5b 2036 SUPERFAMILY SSF49265 1659 1745 1.32E-8 T 14-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 MB46_02915 bc784e86767c6b82c9fc00b779e73c5b 2036 Pfam PF00041 Fibronectin type III domain 1572 1636 1.9E-7 T 14-10-2018 IPR003961 Fibronectin type III GO:0005515 MB46_02915 bc784e86767c6b82c9fc00b779e73c5b 2036 Pfam PF00041 Fibronectin type III domain 1480 1549 2.7E-8 T 14-10-2018 IPR003961 Fibronectin type III GO:0005515 MB46_02915 bc784e86767c6b82c9fc00b779e73c5b 2036 Gene3D G3DSA:2.60.40.10 1657 1745 4.0E-8 T 14-10-2018 IPR013783 Immunoglobulin-like fold MB46_02915 bc784e86767c6b82c9fc00b779e73c5b 2036 Gene3D G3DSA:2.60.40.10 1460 1558 1.4E-19 T 14-10-2018 IPR013783 Immunoglobulin-like fold MB46_02915 bc784e86767c6b82c9fc00b779e73c5b 2036 SMART SM00060 1561 1640 0.0034 T 14-10-2018 IPR003961 Fibronectin type III GO:0005515 MB46_02915 bc784e86767c6b82c9fc00b779e73c5b 2036 SMART SM00060 1472 1546 5.1E-11 T 14-10-2018 IPR003961 Fibronectin type III GO:0005515 MB46_02915 bc784e86767c6b82c9fc00b779e73c5b 2036 SMART SM00060 1659 1738 0.24 T 14-10-2018 IPR003961 Fibronectin type III GO:0005515 MB46_02915 bc784e86767c6b82c9fc00b779e73c5b 2036 Gene3D G3DSA:2.60.40.10 1559 1650 3.2E-10 T 14-10-2018 IPR013783 Immunoglobulin-like fold MB46_02915 bc784e86767c6b82c9fc00b779e73c5b 2036 SUPERFAMILY SSF49265 1471 1644 1.85E-28 T 14-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 MB46_17860 a951890d1186e4add13c5bbe0465e341 184 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 8 98 9.8E-10 T 14-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 MB46_17860 a951890d1186e4add13c5bbe0465e341 184 SUPERFAMILY SSF50475 7 130 2.48E-11 T 14-10-2018 MB46_17860 a951890d1186e4add13c5bbe0465e341 184 Gene3D G3DSA:2.30.110.10 3 130 1.4E-20 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 MB46_15560 6b3e4aef24a4cf912d7fca635d48473c 64 Pfam PF06348 Protein of unknown function (DUF1059) 15 54 2.2E-4 T 14-10-2018 IPR009409 Protein of unknown function DUF1059 MB46_13355 d0ee663a671c06a66ac78ff88facc781 237 ProSitePatterns PS00585 Ribosomal protein S5 signature. 87 119 - T 14-10-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site MB46_13355 d0ee663a671c06a66ac78ff88facc781 237 SUPERFAMILY SSF54768 67 135 2.62E-22 T 14-10-2018 MB46_13355 d0ee663a671c06a66ac78ff88facc781 237 Gene3D G3DSA:3.30.230.10 133 225 3.1E-33 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MB46_13355 d0ee663a671c06a66ac78ff88facc781 237 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 44 222 33.841 T 14-10-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 MB46_13355 d0ee663a671c06a66ac78ff88facc781 237 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 68 221 2.6E-65 T 14-10-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 MB46_13355 d0ee663a671c06a66ac78ff88facc781 237 SUPERFAMILY SSF54211 139 217 9.1E-24 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MB46_13355 d0ee663a671c06a66ac78ff88facc781 237 Pfam PF00333 Ribosomal protein S5, N-terminal domain 71 134 4.5E-28 T 14-10-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 MB46_13355 d0ee663a671c06a66ac78ff88facc781 237 Gene3D G3DSA:3.30.160.20 62 131 2.6E-29 T 14-10-2018 MB46_13355 d0ee663a671c06a66ac78ff88facc781 237 Pfam PF03719 Ribosomal protein S5, C-terminal domain 146 216 1.2E-26 T 14-10-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 MB46_04525 3fd5c46b91bb2ef4d584635001e03110 317 PRINTS PR00412 Epoxide hydrolase signature 127 140 1.9E-5 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MB46_04525 3fd5c46b91bb2ef4d584635001e03110 317 PRINTS PR00412 Epoxide hydrolase signature 63 81 1.9E-5 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MB46_04525 3fd5c46b91bb2ef4d584635001e03110 317 PRINTS PR00412 Epoxide hydrolase signature 255 271 1.9E-5 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MB46_04525 3fd5c46b91bb2ef4d584635001e03110 317 PRINTS PR00412 Epoxide hydrolase signature 288 310 1.9E-5 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MB46_04525 3fd5c46b91bb2ef4d584635001e03110 317 Pfam PF12146 Serine aminopeptidase, S33 54 299 3.2E-17 T 14-10-2018 IPR022742 Serine aminopeptidase, S33 MB46_04525 3fd5c46b91bb2ef4d584635001e03110 317 PRINTS PR00111 Alpha/beta hydrolase fold signature 127 140 5.7E-9 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MB46_04525 3fd5c46b91bb2ef4d584635001e03110 317 PRINTS PR00111 Alpha/beta hydrolase fold signature 257 271 5.7E-9 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MB46_04525 3fd5c46b91bb2ef4d584635001e03110 317 PRINTS PR00111 Alpha/beta hydrolase fold signature 81 96 5.7E-9 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MB46_04525 3fd5c46b91bb2ef4d584635001e03110 317 Gene3D G3DSA:3.40.50.1820 24 314 1.1E-46 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_04525 3fd5c46b91bb2ef4d584635001e03110 317 SUPERFAMILY SSF53474 34 313 2.1E-47 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_14405 02aa3ca210a5faa4c50cad016f068bf7 560 Gene3D G3DSA:3.40.462.40 91 506 2.4E-133 T 14-10-2018 MB46_14405 02aa3ca210a5faa4c50cad016f068bf7 560 Gene3D G3DSA:1.10.45.10 511 550 8.0E-8 T 14-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 MB46_14405 02aa3ca210a5faa4c50cad016f068bf7 560 SUPERFAMILY SSF55103 292 554 9.32E-36 T 14-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 MB46_14405 02aa3ca210a5faa4c50cad016f068bf7 560 SUPERFAMILY SSF56176 57 289 6.54E-47 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 MB46_14405 02aa3ca210a5faa4c50cad016f068bf7 560 Gene3D G3DSA:3.30.465.40 78 288 2.4E-133 T 14-10-2018 MB46_14405 02aa3ca210a5faa4c50cad016f068bf7 560 Pfam PF01565 FAD binding domain 110 247 2.7E-32 T 14-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 MB46_14405 02aa3ca210a5faa4c50cad016f068bf7 560 Pfam PF02913 FAD linked oxidases, C-terminal domain 289 549 1.6E-36 T 14-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 MB46_09420 da0b1c9d1db5ddad71c47a32f675f7af 354 Gene3D G3DSA:3.40.50.720 135 321 1.7E-81 T 14-10-2018 MB46_09420 da0b1c9d1db5ddad71c47a32f675f7af 354 Gene3D G3DSA:3.40.50.720 60 346 1.7E-81 T 14-10-2018 MB46_09420 da0b1c9d1db5ddad71c47a32f675f7af 354 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 144 316 3.5E-47 T 14-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 MB46_09420 da0b1c9d1db5ddad71c47a32f675f7af 354 SUPERFAMILY SSF51735 137 317 3.3E-47 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_09420 da0b1c9d1db5ddad71c47a32f675f7af 354 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 256 272 - T 14-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site MB46_05095 55c45027ada6259094fe42313acdf420 545 SUPERFAMILY SSF53697 22 374 4.7E-68 T 14-10-2018 MB46_05095 55c45027ada6259094fe42313acdf420 545 PRINTS PR00662 Glucose-6-phosphate isomerase signature 260 281 7.6E-7 T 14-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MB46_05095 55c45027ada6259094fe42313acdf420 545 PRINTS PR00662 Glucose-6-phosphate isomerase signature 83 102 7.6E-7 T 14-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MB46_05095 55c45027ada6259094fe42313acdf420 545 PRINTS PR00662 Glucose-6-phosphate isomerase signature 187 205 7.6E-7 T 14-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MB46_05095 55c45027ada6259094fe42313acdf420 545 Gene3D G3DSA:3.40.50.10490 326 376 2.4E-10 T 14-10-2018 MB46_05095 55c45027ada6259094fe42313acdf420 545 Pfam PF00342 Phosphoglucose isomerase 79 224 6.9E-5 T 14-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MB46_05095 55c45027ada6259094fe42313acdf420 545 Gene3D G3DSA:3.40.50.10490 46 212 1.9E-35 T 14-10-2018 MB46_02495 d6b02606d9aec80928f504ad303fdff3 335 SUPERFAMILY SSF51735 1 317 2.25E-78 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_02495 d6b02606d9aec80928f504ad303fdff3 335 Pfam PF16363 GDP-mannose 4,6 dehydratase 5 310 9.4E-54 T 14-10-2018 IPR016040 NAD(P)-binding domain MB46_02495 d6b02606d9aec80928f504ad303fdff3 335 Gene3D G3DSA:3.40.50.720 1 323 1.2E-88 T 14-10-2018 MB46_05245 1f1bd74b403e86e0c212b5c28f2e0b27 152 SUPERFAMILY SSF52833 3 151 2.2E-40 T 14-10-2018 IPR036249 Thioredoxin-like superfamily MB46_05245 1f1bd74b403e86e0c212b5c28f2e0b27 152 Gene3D G3DSA:3.40.30.10 1 152 3.6E-41 T 14-10-2018 MB46_05245 1f1bd74b403e86e0c212b5c28f2e0b27 152 Pfam PF00578 AhpC/TSA family 5 129 1.2E-31 T 14-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 MB46_05245 1f1bd74b403e86e0c212b5c28f2e0b27 152 PIRSF PIRSF000239 1 152 8.9E-19 T 14-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 MB46_16395 06af782cd16c3a4129fe2dcf03d73f28 75 SUPERFAMILY SSF55008 3 71 2.36E-14 T 14-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 MB46_16395 06af782cd16c3a4129fe2dcf03d73f28 75 ProSitePatterns PS01047 Heavy-metal-associated domain. 9 38 - T 14-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 MB46_16395 06af782cd16c3a4129fe2dcf03d73f28 75 Pfam PF00403 Heavy-metal-associated domain 6 68 5.4E-14 T 14-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 MB46_16395 06af782cd16c3a4129fe2dcf03d73f28 75 Gene3D G3DSA:3.30.70.100 1 70 2.1E-18 T 14-10-2018 MB46_09225 656eeb73b63619e5ea87ab169958a77c 436 Gene3D G3DSA:1.20.1250.20 24 404 9.9E-29 T 14-10-2018 MB46_09225 656eeb73b63619e5ea87ab169958a77c 436 SUPERFAMILY SSF103473 28 408 7.98E-32 T 14-10-2018 IPR036259 MFS transporter superfamily MB46_09225 656eeb73b63619e5ea87ab169958a77c 436 Pfam PF07690 Major Facilitator Superfamily 36 330 1.8E-14 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MB46_09455 5119417a1e64b8440295b031fe9db066 144 Pfam PF00578 AhpC/TSA family 2 121 2.9E-30 T 14-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 MB46_09455 5119417a1e64b8440295b031fe9db066 144 Gene3D G3DSA:3.40.30.10 1 144 5.9E-38 T 14-10-2018 MB46_09455 5119417a1e64b8440295b031fe9db066 144 SUPERFAMILY SSF52833 1 144 1.03E-36 T 14-10-2018 IPR036249 Thioredoxin-like superfamily MB46_02425 edde236adb71cfb08fc02a87c134392a 340 SUPERFAMILY SSF55060 205 329 2.63E-24 T 14-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily MB46_02425 edde236adb71cfb08fc02a87c134392a 340 Gene3D G3DSA:3.30.230.10 24 201 1.6E-51 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MB46_02425 edde236adb71cfb08fc02a87c134392a 340 PIRSF PIRSF010376 31 337 1.4E-68 T 14-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 MB46_02425 edde236adb71cfb08fc02a87c134392a 340 Gene3D G3DSA:3.30.70.890 204 340 2.3E-37 T 14-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily MB46_02425 edde236adb71cfb08fc02a87c134392a 340 SUPERFAMILY SSF54211 32 198 7.59E-37 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MB46_02425 edde236adb71cfb08fc02a87c134392a 340 Hamap MF_00061 Putative 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 33 329 28.261 T 14-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 MB46_02425 edde236adb71cfb08fc02a87c134392a 340 Pfam PF00288 GHMP kinases N terminal domain 128 186 3.4E-10 T 14-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 MB46_02425 edde236adb71cfb08fc02a87c134392a 340 Pfam PF08544 GHMP kinases C terminal 248 323 5.3E-9 T 14-10-2018 IPR013750 GHMP kinase, C-terminal domain MB46_02425 edde236adb71cfb08fc02a87c134392a 340 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 32 313 8.5E-47 T 14-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 MB46_14410 774043f554f7c3a4c7b73ca8b334837e 277 Pfam PF00106 short chain dehydrogenase 12 205 1.0E-46 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_14410 774043f554f7c3a4c7b73ca8b334837e 277 SUPERFAMILY SSF51735 7 267 1.14E-59 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_14410 774043f554f7c3a4c7b73ca8b334837e 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 181 6.4E-21 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_14410 774043f554f7c3a4c7b73ca8b334837e 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 87 98 6.4E-21 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_14410 774043f554f7c3a4c7b73ca8b334837e 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 186 203 6.4E-21 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_14410 774043f554f7c3a4c7b73ca8b334837e 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 6.4E-21 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_14410 774043f554f7c3a4c7b73ca8b334837e 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 136 152 6.4E-21 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_14410 774043f554f7c3a4c7b73ca8b334837e 277 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 87 98 4.3E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_14410 774043f554f7c3a4c7b73ca8b334837e 277 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 162 181 4.3E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_14410 774043f554f7c3a4c7b73ca8b334837e 277 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 142 150 4.3E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_14410 774043f554f7c3a4c7b73ca8b334837e 277 Gene3D G3DSA:3.40.50.720 2 248 1.8E-63 T 14-10-2018 MB46_14410 774043f554f7c3a4c7b73ca8b334837e 277 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 149 177 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MB46_10715 f37b02f4f291094cba145e46496ee522 206 Gene3D G3DSA:3.90.950.10 1 204 7.3E-69 T 14-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like MB46_10715 f37b02f4f291094cba145e46496ee522 206 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 4 197 1.1E-48 T 14-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 MB46_10715 f37b02f4f291094cba145e46496ee522 206 SUPERFAMILY SSF52972 3 201 1.6E-62 T 14-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like MB46_10715 f37b02f4f291094cba145e46496ee522 206 Hamap MF_01405 dITP/XTP pyrophosphatase. 3 202 43.078 T 14-10-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 KEGG: 00230+3.6.1.66 MB46_10715 f37b02f4f291094cba145e46496ee522 206 Pfam PF01725 Ham1 family 5 197 2.3E-54 T 14-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 MB46_03605 9da4c893b59958db658dd0a043d930da 257 ProSitePatterns PS01273 Coenzyme A transferases signature 1. 18 33 - T 14-10-2018 IPR004163 Coenzyme A transferase binding site GO:0008410 Reactome: R-HSA-77108 MB46_03605 9da4c893b59958db658dd0a043d930da 257 Pfam PF01144 Coenzyme A transferase 9 234 1.0E-74 T 14-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 MB46_03605 9da4c893b59958db658dd0a043d930da 257 Gene3D G3DSA:3.40.1080.10 1 234 1.5E-97 T 14-10-2018 MB46_03605 9da4c893b59958db658dd0a043d930da 257 SMART SM00882 6 235 2.5E-86 T 14-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 MB46_03605 9da4c893b59958db658dd0a043d930da 257 SUPERFAMILY SSF100950 2 239 5.58E-86 T 14-10-2018 IPR037171 NagB/RpiA transferase-like MB46_18795 73a040c84e9545ff57f32e5a423fb1c7 250 Pfam PF00392 Bacterial regulatory proteins, gntR family 24 80 4.6E-15 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MB46_18795 73a040c84e9545ff57f32e5a423fb1c7 250 Gene3D G3DSA:1.20.120.530 105 243 2.6E-22 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MB46_18795 73a040c84e9545ff57f32e5a423fb1c7 250 SUPERFAMILY SSF48008 107 238 7.85E-25 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MB46_18795 73a040c84e9545ff57f32e5a423fb1c7 250 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 54 70 1.7E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MB46_18795 73a040c84e9545ff57f32e5a423fb1c7 250 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 54 1.7E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MB46_18795 73a040c84e9545ff57f32e5a423fb1c7 250 SMART SM00345 21 80 1.2E-12 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MB46_18795 73a040c84e9545ff57f32e5a423fb1c7 250 SMART SM00895 109 231 7.6E-18 T 14-10-2018 IPR011711 GntR, C-terminal MB46_18795 73a040c84e9545ff57f32e5a423fb1c7 250 Gene3D G3DSA:1.10.10.10 11 85 5.5E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_18795 73a040c84e9545ff57f32e5a423fb1c7 250 SUPERFAMILY SSF46785 19 89 1.86E-17 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_18795 73a040c84e9545ff57f32e5a423fb1c7 250 Pfam PF07729 FCD domain 109 230 1.7E-21 T 14-10-2018 IPR011711 GntR, C-terminal MB46_17440 8f1786fdb48fcd8a08a2e0ebb4b28484 372 SUPERFAMILY SSF54991 260 369 6.02E-8 T 14-10-2018 IPR036690 Ferrodoxin-fold anticodon-binding domain superfamily KEGG: 00970+6.1.1.20 MB46_17440 8f1786fdb48fcd8a08a2e0ebb4b28484 372 SUPERFAMILY SSF55681 48 253 2.24E-24 T 14-10-2018 MB46_17440 8f1786fdb48fcd8a08a2e0ebb4b28484 372 SMART SM00896 264 370 6.1E-6 T 14-10-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 MB46_17440 8f1786fdb48fcd8a08a2e0ebb4b28484 372 Gene3D G3DSA:3.30.930.10 9 257 5.5E-45 T 14-10-2018 MB46_17440 8f1786fdb48fcd8a08a2e0ebb4b28484 372 Pfam PF01409 tRNA synthetases class II core domain (F) 80 253 3.8E-29 T 14-10-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 MB46_17440 8f1786fdb48fcd8a08a2e0ebb4b28484 372 Pfam PF03147 Ferredoxin-fold anticodon binding domain 264 365 1.2E-6 T 14-10-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 MB46_17440 8f1786fdb48fcd8a08a2e0ebb4b28484 372 Gene3D G3DSA:3.30.70.380 266 370 4.3E-6 T 14-10-2018 IPR036690 Ferrodoxin-fold anticodon-binding domain superfamily KEGG: 00970+6.1.1.20 MB46_13095 841d19952ca5fb50b213f44e792cacf9 344 SUPERFAMILY SSF50129 6 143 2.22E-30 T 14-10-2018 IPR011032 GroES-like superfamily MB46_13095 841d19952ca5fb50b213f44e792cacf9 344 Gene3D G3DSA:3.40.50.720 128 305 2.0E-116 T 14-10-2018 MB46_13095 841d19952ca5fb50b213f44e792cacf9 344 SUPERFAMILY SSF51735 125 302 3.16E-47 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_13095 841d19952ca5fb50b213f44e792cacf9 344 Gene3D G3DSA:3.90.180.10 21 333 2.0E-116 T 14-10-2018 MB46_13095 841d19952ca5fb50b213f44e792cacf9 344 Pfam PF00107 Zinc-binding dehydrogenase 160 292 2.5E-21 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 MB46_13095 841d19952ca5fb50b213f44e792cacf9 344 SMART SM00829 20 334 1.2E-7 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MB46_13095 841d19952ca5fb50b213f44e792cacf9 344 Pfam PF16884 N-terminal domain of oxidoreductase 8 112 1.9E-33 T 14-10-2018 MB46_17445 b3aa6cf30acffb9986e122539d958793 553 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 257 263 - T 14-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 MB46_17445 b3aa6cf30acffb9986e122539d958793 553 Pfam PF05175 Methyltransferase small domain 159 264 3.0E-8 T 14-10-2018 IPR007848 Methyltransferase small domain GO:0008168 MB46_17445 b3aa6cf30acffb9986e122539d958793 553 Gene3D G3DSA:3.40.50.150 136 341 1.0E-27 T 14-10-2018 MB46_17445 b3aa6cf30acffb9986e122539d958793 553 SUPERFAMILY SSF53335 173 310 2.41E-23 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MB46_16420 5c88a7aaf45a5b75dc8ef0088a9866c0 561 PIRSF PIRSF000732 1 555 4.1E-142 T 14-10-2018 IPR024692 Phosphotransferase system, enzyme I GO:0008965|GO:0009401 MB46_16420 5c88a7aaf45a5b75dc8ef0088a9866c0 561 Gene3D G3DSA:3.50.30.10 6 230 6.5E-47 T 14-10-2018 MB46_16420 5c88a7aaf45a5b75dc8ef0088a9866c0 561 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 484 496 1.2E-17 T 14-10-2018 MB46_16420 5c88a7aaf45a5b75dc8ef0088a9866c0 561 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 429 444 1.2E-17 T 14-10-2018 MB46_16420 5c88a7aaf45a5b75dc8ef0088a9866c0 561 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 446 461 1.2E-17 T 14-10-2018 MB46_16420 5c88a7aaf45a5b75dc8ef0088a9866c0 561 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 285 304 1.2E-17 T 14-10-2018 MB46_16420 5c88a7aaf45a5b75dc8ef0088a9866c0 561 SUPERFAMILY SSF52009 123 236 3.4E-26 T 14-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 MB46_16420 5c88a7aaf45a5b75dc8ef0088a9866c0 561 Pfam PF05524 PEP-utilising enzyme, N-terminal 6 124 5.4E-18 T 14-10-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 MB46_16420 5c88a7aaf45a5b75dc8ef0088a9866c0 561 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 254 523 1.3E-73 T 14-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 MB46_16420 5c88a7aaf45a5b75dc8ef0088a9866c0 561 Gene3D G3DSA:3.20.20.60 244 555 1.9E-90 T 14-10-2018 MB46_16420 5c88a7aaf45a5b75dc8ef0088a9866c0 561 SUPERFAMILY SSF47831 38 141 1.83E-18 T 14-10-2018 IPR036618 PtsI, HPr-binding domain superfamily GO:0009401 MB46_16420 5c88a7aaf45a5b75dc8ef0088a9866c0 561 SUPERFAMILY SSF51621 245 526 2.88E-78 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 MB46_16420 5c88a7aaf45a5b75dc8ef0088a9866c0 561 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 55 544 7.8E-105 T 14-10-2018 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 MB46_16420 5c88a7aaf45a5b75dc8ef0088a9866c0 561 Gene3D G3DSA:1.10.274.10 23 144 6.5E-47 T 14-10-2018 IPR036618 PtsI, HPr-binding domain superfamily GO:0009401 MB46_16420 5c88a7aaf45a5b75dc8ef0088a9866c0 561 Pfam PF00391 PEP-utilising enzyme, mobile domain 153 222 2.3E-18 T 14-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 MB46_16090 350a14c8b7a62db5adddad7e8b3f75f0 316 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 38 262 1.3E-58 T 14-10-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_16090 350a14c8b7a62db5adddad7e8b3f75f0 316 Pfam PF02096 60Kd inner membrane protein 39 262 2.0E-54 T 14-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 MB46_15425 283b815e5ffc91ff1225eb03f817a861 328 Pfam PF00356 Bacterial regulatory proteins, lacI family 2 43 3.1E-9 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MB46_15425 283b815e5ffc91ff1225eb03f817a861 328 SMART SM00354 2 68 1.5E-7 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MB46_15425 283b815e5ffc91ff1225eb03f817a861 328 Gene3D G3DSA:1.10.260.40 1 51 9.7E-12 T 14-10-2018 MB46_15425 283b815e5ffc91ff1225eb03f817a861 328 SUPERFAMILY SSF47413 2 56 3.75E-8 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MB46_15425 283b815e5ffc91ff1225eb03f817a861 328 Pfam PF13377 Periplasmic binding protein-like domain 161 322 2.2E-35 T 14-10-2018 MB46_15425 283b815e5ffc91ff1225eb03f817a861 328 Gene3D G3DSA:3.40.50.2300 52 299 3.0E-53 T 14-10-2018 MB46_15425 283b815e5ffc91ff1225eb03f817a861 328 SUPERFAMILY SSF53822 59 324 1.01E-48 T 14-10-2018 IPR028082 Periplasmic binding protein-like I MB46_15425 283b815e5ffc91ff1225eb03f817a861 328 Gene3D G3DSA:3.40.50.2300 153 282 3.0E-53 T 14-10-2018 MB46_18615 78de8d51531cac508c4d89f9049ce4f9 381 SUPERFAMILY SSF103473 2 363 4.05E-34 T 14-10-2018 IPR036259 MFS transporter superfamily MB46_18615 78de8d51531cac508c4d89f9049ce4f9 381 Pfam PF07690 Major Facilitator Superfamily 2 228 4.9E-13 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MB46_18615 78de8d51531cac508c4d89f9049ce4f9 381 Gene3D G3DSA:1.20.1250.20 1 367 1.8E-32 T 14-10-2018 MB46_00225 64932a7252ef491c00c2814eb80a29ed 297 SUPERFAMILY SSF161098 60 281 1.44E-50 T 14-10-2018 IPR035906 MetI-like superfamily MB46_00225 64932a7252ef491c00c2814eb80a29ed 297 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 86 291 1.1E-18 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_00225 64932a7252ef491c00c2814eb80a29ed 297 Gene3D G3DSA:1.10.3720.10 50 296 1.4E-59 T 14-10-2018 IPR035906 MetI-like superfamily MB46_09080 38e78a1d569e580fbb4b64f14b01de59 348 SMART SM00898 2 155 5.0E-17 T 14-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 MB46_09080 38e78a1d569e580fbb4b64f14b01de59 348 SUPERFAMILY SSF57716 292 330 7.98E-12 T 14-10-2018 MB46_09080 38e78a1d569e580fbb4b64f14b01de59 348 SMART SM01232 169 262 6.2E-23 T 14-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 MB46_09080 38e78a1d569e580fbb4b64f14b01de59 348 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 85 6.4E-6 T 14-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 MB46_09080 38e78a1d569e580fbb4b64f14b01de59 348 SUPERFAMILY SSF81624 2 170 1.73E-20 T 14-10-2018 IPR035937 MutM-like, N-terminal MB46_09080 38e78a1d569e580fbb4b64f14b01de59 348 Pfam PF06827 Zinc finger found in FPG and IleRS 302 330 4.1E-9 T 14-10-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 MB46_09080 38e78a1d569e580fbb4b64f14b01de59 348 Gene3D G3DSA:3.20.190.10 2 89 4.3E-11 T 14-10-2018 IPR035937 MutM-like, N-terminal MB46_09080 38e78a1d569e580fbb4b64f14b01de59 348 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 169 257 8.4E-17 T 14-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 MB46_09080 38e78a1d569e580fbb4b64f14b01de59 348 Gene3D G3DSA:1.10.8.50 171 331 1.3E-34 T 14-10-2018 MB46_09080 38e78a1d569e580fbb4b64f14b01de59 348 SUPERFAMILY SSF46946 168 252 1.46E-20 T 14-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 MB46_09045 bac03001362d5a508e7699fdcdef5cc4 428 SMART SM01086 320 414 2.8E-34 T 14-10-2018 IPR019489 Clp ATPase, C-terminal MB46_09045 bac03001362d5a508e7699fdcdef5cc4 428 Gene3D G3DSA:3.30.50.30 2 50 2.3E-24 T 14-10-2018 IPR038366 Zinc finger, ClpX C4-type superfamily MB46_09045 bac03001362d5a508e7699fdcdef5cc4 428 SMART SM00994 10 49 5.0E-24 T 14-10-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 MB46_09045 bac03001362d5a508e7699fdcdef5cc4 428 SUPERFAMILY SSF52540 60 405 2.78E-74 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_09045 bac03001362d5a508e7699fdcdef5cc4 428 Pfam PF06689 ClpX C4-type zinc finger 12 48 6.5E-21 T 14-10-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 MB46_09045 bac03001362d5a508e7699fdcdef5cc4 428 Gene3D G3DSA:1.10.8.60 319 426 5.4E-37 T 14-10-2018 MB46_09045 bac03001362d5a508e7699fdcdef5cc4 428 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 320 397 1.1E-16 T 14-10-2018 IPR019489 Clp ATPase, C-terminal MB46_09045 bac03001362d5a508e7699fdcdef5cc4 428 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 2 418 51.526 T 14-10-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 MB46_09045 bac03001362d5a508e7699fdcdef5cc4 428 Gene3D G3DSA:3.40.50.300 54 317 2.8E-104 T 14-10-2018 MB46_09045 bac03001362d5a508e7699fdcdef5cc4 428 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 8 415 4.5E-194 T 14-10-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 MB46_09045 bac03001362d5a508e7699fdcdef5cc4 428 Pfam PF07724 AAA domain (Cdc48 subfamily) 119 314 1.4E-49 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MB46_09045 bac03001362d5a508e7699fdcdef5cc4 428 SMART SM00382 118 336 6.4E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_09045 bac03001362d5a508e7699fdcdef5cc4 428 SUPERFAMILY SSF57716 11 46 1.25E-11 T 14-10-2018 MB46_08745 0fceaff38e50090bf8b47f44bbf2ac0c 145 SUPERFAMILY SSF54593 4 138 8.11E-27 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MB46_08745 0fceaff38e50090bf8b47f44bbf2ac0c 145 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 129 4.0E-9 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MB46_08745 0fceaff38e50090bf8b47f44bbf2ac0c 145 Gene3D G3DSA:3.10.180.10 2 145 7.9E-50 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MB46_05395 1bbe06996ea089aaed0575566a6d5645 576 Gene3D G3DSA:1.10.8.60 406 450 6.5E-59 T 14-10-2018 MB46_05395 1bbe06996ea089aaed0575566a6d5645 576 TIGRFAM TIGR03689 pup_AAA: proteasome ATPase 29 553 1.1E-249 T 14-10-2018 IPR022482 Proteasome ATPase GO:0000502|GO:0010498|GO:0016887|GO:0019941 MB46_05395 1bbe06996ea089aaed0575566a6d5645 576 Hamap MF_02112 Proteasome-associated ATPase [mpa]. 31 554 50.312 T 14-10-2018 IPR022482 Proteasome ATPase GO:0000502|GO:0010498|GO:0016887|GO:0019941 MB46_05395 1bbe06996ea089aaed0575566a6d5645 576 Pfam PF16450 Proteasomal ATPase OB/ID domain 89 214 8.3E-42 T 14-10-2018 IPR032501 Proteasomal ATPase, OB/ID domain MB46_05395 1bbe06996ea089aaed0575566a6d5645 576 ProSitePatterns PS00674 AAA-protein family signature. 375 393 - T 14-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 MB46_05395 1bbe06996ea089aaed0575566a6d5645 576 Gene3D G3DSA:2.40.50.140 89 143 1.6E-13 T 14-10-2018 MB46_05395 1bbe06996ea089aaed0575566a6d5645 576 Gene3D G3DSA:2.40.50.140 144 216 3.8E-21 T 14-10-2018 MB46_05395 1bbe06996ea089aaed0575566a6d5645 576 SUPERFAMILY SSF52540 215 526 1.54E-50 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_05395 1bbe06996ea089aaed0575566a6d5645 576 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 257 405 2.4E-46 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MB46_05395 1bbe06996ea089aaed0575566a6d5645 576 Gene3D G3DSA:3.40.50.300 218 405 6.5E-59 T 14-10-2018 MB46_05395 1bbe06996ea089aaed0575566a6d5645 576 SMART SM00382 253 407 4.8E-21 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_16370 9b92f04887295c90a03117f33f88a566 331 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 128 321 3.6E-15 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_16370 9b92f04887295c90a03117f33f88a566 331 Gene3D G3DSA:1.10.3720.10 71 324 1.4E-61 T 14-10-2018 IPR035906 MetI-like superfamily MB46_16370 9b92f04887295c90a03117f33f88a566 331 SUPERFAMILY SSF161098 75 314 4.84E-53 T 14-10-2018 IPR035906 MetI-like superfamily MB46_16325 0c4bdb5c074e9152abcd3c55194050c3 316 SUPERFAMILY SSF103481 195 284 4.18E-15 T 14-10-2018 MB46_16325 0c4bdb5c074e9152abcd3c55194050c3 316 SUPERFAMILY SSF103481 43 144 7.59E-8 T 14-10-2018 MB46_16325 0c4bdb5c074e9152abcd3c55194050c3 316 Pfam PF00892 EamA-like transporter family 11 141 3.2E-14 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MB46_16325 0c4bdb5c074e9152abcd3c55194050c3 316 Pfam PF00892 EamA-like transporter family 151 284 1.3E-19 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MB46_09270 5fc6e45e38a563386df57f0856c91ad7 194 Pfam PF00440 Bacterial regulatory proteins, tetR family 9 51 1.0E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MB46_09270 5fc6e45e38a563386df57f0856c91ad7 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 52 1.9E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MB46_09270 5fc6e45e38a563386df57f0856c91ad7 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 8 21 1.9E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MB46_09270 5fc6e45e38a563386df57f0856c91ad7 194 SUPERFAMILY SSF46689 2 54 5.34E-14 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MB46_09270 5fc6e45e38a563386df57f0856c91ad7 194 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 79 151 1.6E-7 T 14-10-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 MB46_09270 5fc6e45e38a563386df57f0856c91ad7 194 SUPERFAMILY SSF48498 78 187 6.67E-17 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily MB46_09270 5fc6e45e38a563386df57f0856c91ad7 194 PRINTS PR00400 Tetracycline repressor protein signature 131 150 5.0E-11 T 14-10-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 MB46_09270 5fc6e45e38a563386df57f0856c91ad7 194 PRINTS PR00400 Tetracycline repressor protein signature 20 43 5.0E-11 T 14-10-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 MB46_09270 5fc6e45e38a563386df57f0856c91ad7 194 PRINTS PR00400 Tetracycline repressor protein signature 75 94 5.0E-11 T 14-10-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 MB46_09270 5fc6e45e38a563386df57f0856c91ad7 194 Gene3D G3DSA:1.10.357.10 66 188 1.5E-18 T 14-10-2018 MB46_09270 5fc6e45e38a563386df57f0856c91ad7 194 ProSitePatterns PS01081 TetR-type HTH domain signature. 20 51 - T 14-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site MB46_09270 5fc6e45e38a563386df57f0856c91ad7 194 Gene3D G3DSA:1.10.10.60 2 61 4.2E-24 T 14-10-2018 MB46_03245 c72e7e4fe6179fd6ca39d69457d19535 429 Pfam PF07907 YibE/F-like protein 165 400 6.7E-68 T 14-10-2018 IPR012507 YibE/F-like MB46_00185 414b6b1031787b23e8018b3f765d84c3 283 Gene3D G3DSA:3.40.50.720 1 282 5.3E-74 T 14-10-2018 MB46_00185 414b6b1031787b23e8018b3f765d84c3 283 SUPERFAMILY SSF51735 1 274 6.7E-24 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_00185 414b6b1031787b23e8018b3f765d84c3 283 Pfam PF01370 NAD dependent epimerase/dehydratase family 19 172 9.1E-7 T 14-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 MB46_11705 459b4e350b0127984c33069588a445e8 544 SUPERFAMILY SSF53850 43 530 9.95E-93 T 14-10-2018 MB46_11705 459b4e350b0127984c33069588a445e8 544 Gene3D G3DSA:3.10.105.10 282 517 1.2E-91 T 14-10-2018 MB46_11705 459b4e350b0127984c33069588a445e8 544 Gene3D G3DSA:3.90.76.10 53 204 1.2E-91 T 14-10-2018 MB46_11705 459b4e350b0127984c33069588a445e8 544 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 86 465 1.0E-69 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain MB46_11705 459b4e350b0127984c33069588a445e8 544 PIRSF PIRSF002741 2 538 2.0E-59 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 MB46_11705 459b4e350b0127984c33069588a445e8 544 Gene3D G3DSA:3.40.190.10 205 526 1.2E-91 T 14-10-2018 MB46_00850 333a322ec1ea05eaa639fb14b95c1e89 507 Gene3D G3DSA:3.40.190.10 145 236 1.8E-66 T 14-10-2018 MB46_00850 333a322ec1ea05eaa639fb14b95c1e89 507 SUPERFAMILY SSF53850 16 278 1.46E-66 T 14-10-2018 MB46_00850 333a322ec1ea05eaa639fb14b95c1e89 507 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 328 503 2.4E-20 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_00850 333a322ec1ea05eaa639fb14b95c1e89 507 SMART SM00062 58 278 9.1E-64 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MB46_00850 333a322ec1ea05eaa639fb14b95c1e89 507 Gene3D G3DSA:3.40.190.10 59 275 1.8E-66 T 14-10-2018 MB46_00850 333a322ec1ea05eaa639fb14b95c1e89 507 SMART SM00079 58 277 5.5E-4 T 14-10-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 MB46_00850 333a322ec1ea05eaa639fb14b95c1e89 507 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 303 398 7.7E-31 T 14-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 MB46_00850 333a322ec1ea05eaa639fb14b95c1e89 507 Gene3D G3DSA:1.10.3720.10 292 505 8.7E-55 T 14-10-2018 IPR035906 MetI-like superfamily MB46_00850 333a322ec1ea05eaa639fb14b95c1e89 507 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 59 276 6.0E-64 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MB46_00850 333a322ec1ea05eaa639fb14b95c1e89 507 SUPERFAMILY SSF161098 303 495 4.71E-46 T 14-10-2018 IPR035906 MetI-like superfamily MB46_17240 81eab12766ccb154399f1342c92d7c16 382 Gene3D G3DSA:3.90.650.10 180 366 1.6E-55 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily MB46_17240 81eab12766ccb154399f1342c92d7c16 382 Pfam PF02769 AIR synthase related protein, C-terminal domain 184 353 2.1E-27 T 14-10-2018 IPR010918 PurM-like, C-terminal domain MB46_17240 81eab12766ccb154399f1342c92d7c16 382 SUPERFAMILY SSF55326 13 177 1.64E-44 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily MB46_17240 81eab12766ccb154399f1342c92d7c16 382 SUPERFAMILY SSF56042 180 351 1.79E-51 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily MB46_17240 81eab12766ccb154399f1342c92d7c16 382 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 13 377 40.443 T 14-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MB46_17240 81eab12766ccb154399f1342c92d7c16 382 Pfam PF00586 AIR synthase related protein, N-terminal domain 68 172 4.0E-15 T 14-10-2018 IPR016188 PurM-like, N-terminal domain MB46_17240 81eab12766ccb154399f1342c92d7c16 382 Gene3D G3DSA:3.30.1330.10 12 177 4.7E-59 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily MB46_17240 81eab12766ccb154399f1342c92d7c16 382 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 13 350 9.8E-122 T 14-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MB46_19815 31986be2c1b38a5a0fcc45c73a6f93c0 144 Gene3D G3DSA:2.10.109.10 29 142 4.3E-38 T 14-10-2018 MB46_19815 31986be2c1b38a5a0fcc45c73a6f93c0 144 SUPERFAMILY SSF51306 19 136 1.57E-32 T 14-10-2018 IPR036286 LexA/Signal peptidase-like superfamily MB46_19815 31986be2c1b38a5a0fcc45c73a6f93c0 144 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 67 78 1.5E-9 T 14-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 MB46_19815 31986be2c1b38a5a0fcc45c73a6f93c0 144 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 56 66 1.5E-9 T 14-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 MB46_19815 31986be2c1b38a5a0fcc45c73a6f93c0 144 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 95 107 1.5E-9 T 14-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 MB46_19815 31986be2c1b38a5a0fcc45c73a6f93c0 144 Pfam PF00717 Peptidase S24-like 59 125 5.0E-16 T 14-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C MB46_10485 ae162e225b58140eb4c7477c383bd0b8 546 Gene3D G3DSA:3.90.76.10 50 222 9.9E-113 T 14-10-2018 MB46_10485 ae162e225b58140eb4c7477c383bd0b8 546 SUPERFAMILY SSF53850 35 541 3.26E-100 T 14-10-2018 MB46_10485 ae162e225b58140eb4c7477c383bd0b8 546 Gene3D G3DSA:3.10.105.10 302 517 9.9E-113 T 14-10-2018 MB46_10485 ae162e225b58140eb4c7477c383bd0b8 546 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 80 464 2.8E-66 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain MB46_10485 ae162e225b58140eb4c7477c383bd0b8 546 PIRSF PIRSF002741 1 541 4.5E-78 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 MB46_10485 ae162e225b58140eb4c7477c383bd0b8 546 Gene3D G3DSA:3.40.190.10 223 530 9.9E-113 T 14-10-2018 MB46_13265 8b733c76356ebafa7af37a592d603718 147 SUPERFAMILY SSF52161 4 144 6.28E-57 T 14-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 MB46_13265 8b733c76356ebafa7af37a592d603718 147 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 15 146 26.812 T 14-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 MB46_13265 8b733c76356ebafa7af37a592d603718 147 PIRSF PIRSF002181 2 147 2.2E-45 T 14-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 MB46_13265 8b733c76356ebafa7af37a592d603718 147 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 6 141 1.9E-58 T 14-10-2018 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_13265 8b733c76356ebafa7af37a592d603718 147 Pfam PF00572 Ribosomal protein L13 14 138 5.0E-54 T 14-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 MB46_13265 8b733c76356ebafa7af37a592d603718 147 Gene3D G3DSA:3.90.1180.10 1 142 1.2E-58 T 14-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 MB46_12270 18d0992e9e619ecd3a3b265a72c0521c 492 PIRSF PIRSF006060 5 483 1.4E-74 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 MB46_12270 18d0992e9e619ecd3a3b265a72c0521c 492 ProSitePatterns PS00218 Amino acid permeases signature. 49 79 - T 14-10-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 MB46_12270 18d0992e9e619ecd3a3b265a72c0521c 492 Gene3D G3DSA:1.20.1740.10 15 478 5.2E-66 T 14-10-2018 MB46_12270 18d0992e9e619ecd3a3b265a72c0521c 492 Pfam PF00324 Amino acid permease 24 458 4.9E-111 T 14-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 MB46_19030 968e05d5f93a6f5fffb2c03717dc21ea 292 PIRSF PIRSF016184 4 292 8.2E-61 T 14-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 MB46_19030 968e05d5f93a6f5fffb2c03717dc21ea 292 Gene3D G3DSA:3.10.310.10 11 288 5.5E-67 T 14-10-2018 MB46_19030 968e05d5f93a6f5fffb2c03717dc21ea 292 Pfam PF02567 Phenazine biosynthesis-like protein 13 291 8.7E-56 T 14-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 MB46_19030 968e05d5f93a6f5fffb2c03717dc21ea 292 SUPERFAMILY SSF54506 9 291 7.57E-52 T 14-10-2018 MB46_19030 968e05d5f93a6f5fffb2c03717dc21ea 292 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 7 291 3.7E-55 T 14-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 MB46_19030 968e05d5f93a6f5fffb2c03717dc21ea 292 Gene3D G3DSA:3.10.310.10 126 287 5.5E-67 T 14-10-2018 MB46_01205 02d25e646edc298bc5636495a44343df 116 SMART SM00418 34 114 2.0E-26 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MB46_01205 02d25e646edc298bc5636495a44343df 116 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 58 69 1.3E-20 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MB46_01205 02d25e646edc298bc5636495a44343df 116 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 36 51 1.3E-20 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MB46_01205 02d25e646edc298bc5636495a44343df 116 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 86 101 1.3E-20 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MB46_01205 02d25e646edc298bc5636495a44343df 116 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 71 86 1.3E-20 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MB46_01205 02d25e646edc298bc5636495a44343df 116 Pfam PF01022 Bacterial regulatory protein, arsR family 41 89 1.9E-14 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MB46_01205 02d25e646edc298bc5636495a44343df 116 Gene3D G3DSA:1.10.10.10 16 115 3.9E-29 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_01205 02d25e646edc298bc5636495a44343df 116 SUPERFAMILY SSF46785 23 113 4.85E-26 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_12525 e75a932e22eef71d6493f0170b6c7574 285 Gene3D G3DSA:3.40.50.10320 12 284 5.5E-77 T 14-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 MB46_12525 e75a932e22eef71d6493f0170b6c7574 285 Pfam PF02585 GlcNAc-PI de-N-acetylase 17 194 1.3E-24 T 14-10-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 MB46_12525 e75a932e22eef71d6493f0170b6c7574 285 SUPERFAMILY SSF102588 15 259 1.7E-51 T 14-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 MB46_02205 83ebd9c0a72a697bf320adc29cf96017 345 Gene3D G3DSA:3.40.190.90 146 307 6.5E-126 T 14-10-2018 MB46_02205 83ebd9c0a72a697bf320adc29cf96017 345 Pfam PF03320 Bacterial fructose-1,6-bisphosphatase, glpX-encoded 26 333 3.8E-136 T 14-10-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 MB46_02205 83ebd9c0a72a697bf320adc29cf96017 345 PIRSF PIRSF004532 24 343 5.7E-139 T 14-10-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 MB46_02205 83ebd9c0a72a697bf320adc29cf96017 345 SUPERFAMILY SSF56655 24 335 2.82E-109 T 14-10-2018 MB46_02205 83ebd9c0a72a697bf320adc29cf96017 345 Gene3D G3DSA:3.30.540.10 30 333 6.5E-126 T 14-10-2018 MB46_02205 83ebd9c0a72a697bf320adc29cf96017 345 TIGRFAM TIGR00330 glpX: fructose-1,6-bisphosphatase, class II 26 337 1.2E-111 T 14-10-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 MB46_10030 07547d427ca90a198263ac6f6f33af0a 169 Pfam PF04542 Sigma-70 region 2 13 77 4.7E-9 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 MB46_10030 07547d427ca90a198263ac6f6f33af0a 169 Pfam PF08281 Sigma-70, region 4 104 153 9.9E-15 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MB46_10030 07547d427ca90a198263ac6f6f33af0a 169 Gene3D G3DSA:1.10.1740.10 1 73 9.9E-10 T 14-10-2018 MB46_10030 07547d427ca90a198263ac6f6f33af0a 169 SUPERFAMILY SSF88946 6 85 8.63E-12 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 MB46_10030 07547d427ca90a198263ac6f6f33af0a 169 SUPERFAMILY SSF88659 102 159 1.21E-13 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like MB46_10030 07547d427ca90a198263ac6f6f33af0a 169 Gene3D G3DSA:1.10.10.10 102 162 1.1E-16 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_10030 07547d427ca90a198263ac6f6f33af0a 169 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 11 159 2.5E-20 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 MB46_10635 d21052ac81524a008c5bf86cbd60a0ae 464 Pfam PF00324 Amino acid permease 27 448 4.2E-95 T 14-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 MB46_10635 d21052ac81524a008c5bf86cbd60a0ae 464 PIRSF PIRSF006060 7 460 2.4E-73 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 MB46_10635 d21052ac81524a008c5bf86cbd60a0ae 464 ProSitePatterns PS00218 Amino acid permeases signature. 51 81 - T 14-10-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 MB46_10635 d21052ac81524a008c5bf86cbd60a0ae 464 Gene3D G3DSA:1.20.1740.10 20 464 1.4E-74 T 14-10-2018 MB46_04805 314aff0036ae2d29022163cdd68f3895 310 Gene3D G3DSA:3.40.50.1100 13 306 1.1E-84 T 14-10-2018 MB46_04805 314aff0036ae2d29022163cdd68f3895 310 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 15 302 1.2E-66 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme MB46_04805 314aff0036ae2d29022163cdd68f3895 310 Gene3D G3DSA:3.40.50.1100 48 147 1.1E-84 T 14-10-2018 MB46_04805 314aff0036ae2d29022163cdd68f3895 310 SUPERFAMILY SSF53686 4 306 6.42E-74 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme MB46_13400 8c201c6dfeff2a2aaf97554b6623cf26 138 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 134 38.724 T 14-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_13400 8c201c6dfeff2a2aaf97554b6623cf26 138 Gene3D G3DSA:3.90.1170.10 1 137 4.3E-49 T 14-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 MB46_13400 8c201c6dfeff2a2aaf97554b6623cf26 138 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 126 7.9E-56 T 14-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_13400 8c201c6dfeff2a2aaf97554b6623cf26 138 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 59 70 - T 14-10-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MB46_13400 8c201c6dfeff2a2aaf97554b6623cf26 138 Pfam PF00252 Ribosomal protein L16p/L10e 4 132 9.7E-47 T 14-10-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 MB46_13400 8c201c6dfeff2a2aaf97554b6623cf26 138 SUPERFAMILY SSF54686 1 136 1.31E-54 T 14-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 MB46_13400 8c201c6dfeff2a2aaf97554b6623cf26 138 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 82 93 - T 14-10-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MB46_13400 8c201c6dfeff2a2aaf97554b6623cf26 138 PRINTS PR00060 Ribosomal protein L16 signature 42 53 1.7E-39 T 14-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_13400 8c201c6dfeff2a2aaf97554b6623cf26 138 PRINTS PR00060 Ribosomal protein L16 signature 58 87 1.7E-39 T 14-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_13400 8c201c6dfeff2a2aaf97554b6623cf26 138 PRINTS PR00060 Ribosomal protein L16 signature 24 36 1.7E-39 T 14-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_13400 8c201c6dfeff2a2aaf97554b6623cf26 138 PRINTS PR00060 Ribosomal protein L16 signature 88 117 1.7E-39 T 14-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_14280 72fe7ebbeb520d26d1c71cc044630aab 214 Pfam PF03458 UPF0126 domain 8 81 2.5E-20 T 14-10-2018 IPR005115 Uncharacterised domain UPF0126 MB46_14280 72fe7ebbeb520d26d1c71cc044630aab 214 Pfam PF03458 UPF0126 domain 94 168 7.6E-21 T 14-10-2018 IPR005115 Uncharacterised domain UPF0126 MB46_07460 256713f4d90978392c68e17ce18ffef9 246 Pfam PF07702 UTRA domain 90 229 2.5E-34 T 14-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 MB46_07460 256713f4d90978392c68e17ce18ffef9 246 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 43 59 6.0E-9 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MB46_07460 256713f4d90978392c68e17ce18ffef9 246 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 29 43 6.0E-9 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MB46_07460 256713f4d90978392c68e17ce18ffef9 246 Gene3D G3DSA:1.10.10.10 3 70 1.5E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_07460 256713f4d90978392c68e17ce18ffef9 246 SUPERFAMILY SSF46785 3 77 1.01E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_07460 256713f4d90978392c68e17ce18ffef9 246 SMART SM00345 11 69 5.9E-18 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MB46_07460 256713f4d90978392c68e17ce18ffef9 246 Gene3D G3DSA:3.40.1410.10 71 239 2.0E-44 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily MB46_07460 256713f4d90978392c68e17ce18ffef9 246 SUPERFAMILY SSF64288 58 237 1.4E-45 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily MB46_07460 256713f4d90978392c68e17ce18ffef9 246 Pfam PF00392 Bacterial regulatory proteins, gntR family 22 69 4.8E-17 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MB46_07460 256713f4d90978392c68e17ce18ffef9 246 SMART SM00866 90 230 6.4E-32 T 14-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 MB46_18980 a6134300d5192609fad3adcb532f7c30 532 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 64 256 1.4E-9 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_18980 a6134300d5192609fad3adcb532f7c30 532 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 351 527 1.5E-16 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_18980 a6134300d5192609fad3adcb532f7c30 532 Gene3D G3DSA:1.10.3720.10 32 268 1.6E-44 T 14-10-2018 IPR035906 MetI-like superfamily MB46_18980 a6134300d5192609fad3adcb532f7c30 532 Gene3D G3DSA:1.10.3720.10 288 530 2.9E-31 T 14-10-2018 IPR035906 MetI-like superfamily MB46_18980 a6134300d5192609fad3adcb532f7c30 532 SUPERFAMILY SSF161098 294 523 6.76E-33 T 14-10-2018 IPR035906 MetI-like superfamily MB46_18980 a6134300d5192609fad3adcb532f7c30 532 SUPERFAMILY SSF161098 28 260 3.16E-39 T 14-10-2018 IPR035906 MetI-like superfamily MB46_12565 1b4e8c39cd78b883b79236644d1dd738 263 Gene3D G3DSA:3.40.50.10320 1 244 6.7E-33 T 14-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 MB46_12565 1b4e8c39cd78b883b79236644d1dd738 263 SUPERFAMILY SSF102588 5 236 6.41E-38 T 14-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 MB46_12565 1b4e8c39cd78b883b79236644d1dd738 263 Pfam PF02585 GlcNAc-PI de-N-acetylase 9 141 3.2E-22 T 14-10-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 MB46_09235 d4c08a9e173bf8481e3e30115391e3d5 344 Pfam PF00296 Luciferase-like monooxygenase 19 297 1.6E-46 T 14-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MB46_09235 d4c08a9e173bf8481e3e30115391e3d5 344 SUPERFAMILY SSF51679 10 335 6.54E-71 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 MB46_09235 d4c08a9e173bf8481e3e30115391e3d5 344 Gene3D G3DSA:3.20.20.30 4 343 1.3E-74 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 MB46_05885 63657850ed213522c4c85fbab4be0e30 763 Gene3D G3DSA:1.50.10.10 322 673 1.7E-115 T 14-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 MB46_05885 63657850ed213522c4c85fbab4be0e30 763 Pfam PF03636 Glycosyl hydrolase family 65, N-terminal domain 20 274 5.4E-41 T 14-10-2018 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 MB46_05885 63657850ed213522c4c85fbab4be0e30 763 Gene3D G3DSA:2.70.98.40 8 278 4.3E-40 T 14-10-2018 IPR037018 Glycoside hydrolase family 65, N-terminal domain superfamily MB46_05885 63657850ed213522c4c85fbab4be0e30 763 Pfam PF03632 Glycosyl hydrolase family 65 central catalytic domain 328 684 1.2E-113 T 14-10-2018 IPR005195 Glycoside hydrolase, family 65, central catalytic GO:0003824|GO:0005975 MB46_05885 63657850ed213522c4c85fbab4be0e30 763 Pfam PF03633 Glycosyl hydrolase family 65, C-terminal domain 692 741 1.2E-10 T 14-10-2018 IPR005194 Glycoside hydrolase family 65, C-terminal MB46_05885 63657850ed213522c4c85fbab4be0e30 763 SUPERFAMILY SSF74650 9 274 2.17E-47 T 14-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 MB46_05885 63657850ed213522c4c85fbab4be0e30 763 Gene3D G3DSA:2.60.420.10 674 753 2.3E-18 T 14-10-2018 MB46_05885 63657850ed213522c4c85fbab4be0e30 763 SUPERFAMILY SSF48208 287 739 2.18E-108 T 14-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 MB46_05885 63657850ed213522c4c85fbab4be0e30 763 PIRSF PIRSF036289 5 755 1.4E-170 T 14-10-2018 IPR017045 Maltose phosphorylase/glycosyl hydrolase/vacuolar acid trehalase MB46_07230 0562679ee8d436a0cb17e6e5bcfe0d2c 77 Gene3D G3DSA:1.10.1470.10 4 67 1.8E-7 T 14-10-2018 IPR036629 YjbJ superfamily MB46_07230 0562679ee8d436a0cb17e6e5bcfe0d2c 77 Pfam PF05532 CsbD-like 5 56 8.6E-15 T 14-10-2018 IPR008462 CsbD-like domain MB46_07230 0562679ee8d436a0cb17e6e5bcfe0d2c 77 SUPERFAMILY SSF69047 5 64 1.22E-10 T 14-10-2018 IPR036629 YjbJ superfamily MB46_05290 36a7de2afe282d81e84b92cdc05b9f4f 667 Pfam PF01844 HNH endonuclease 576 608 6.6E-6 T 14-10-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 MB46_05290 36a7de2afe282d81e84b92cdc05b9f4f 667 Pfam PF02720 Domain of unknown function (DUF222) 449 561 7.6E-9 T 14-10-2018 IPR003870 Domain of unknown function DUF222 MB46_05290 36a7de2afe282d81e84b92cdc05b9f4f 667 Pfam PF02720 Domain of unknown function (DUF222) 75 289 6.6E-15 T 14-10-2018 IPR003870 Domain of unknown function DUF222 MB46_05290 36a7de2afe282d81e84b92cdc05b9f4f 667 SMART SM00507 552 604 1.5E-9 T 14-10-2018 IPR003615 HNH nuclease MB46_10055 25b2b5daab4f45edd199b1e6511bd423 360 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 17 347 9.0E-91 T 14-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 MB46_10055 25b2b5daab4f45edd199b1e6511bd423 360 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 254 273 - T 14-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 MB46_10055 25b2b5daab4f45edd199b1e6511bd423 360 SUPERFAMILY SSF53659 13 360 3.46E-110 T 14-10-2018 MB46_10055 25b2b5daab4f45edd199b1e6511bd423 360 Gene3D G3DSA:3.40.718.10 14 360 1.6E-124 T 14-10-2018 MB46_10055 25b2b5daab4f45edd199b1e6511bd423 360 Hamap MF_01035 3-isopropylmalate dehydrogenase [leuB]. 15 360 56.475 T 14-10-2018 IPR023698 3-isopropylmalate dehydrogenase GO:0003862|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 MB46_10055 25b2b5daab4f45edd199b1e6511bd423 360 SMART SM01329 16 356 1.9E-160 T 14-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 MB46_17495 8cca931eac91a0b2f0fa3a20cb4bc7b3 186 Gene3D G3DSA:1.10.1740.10 5 77 1.1E-15 T 14-10-2018 MB46_17495 8cca931eac91a0b2f0fa3a20cb4bc7b3 186 SUPERFAMILY SSF88659 114 177 5.42E-11 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like MB46_17495 8cca931eac91a0b2f0fa3a20cb4bc7b3 186 Pfam PF08281 Sigma-70, region 4 121 170 2.2E-9 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MB46_17495 8cca931eac91a0b2f0fa3a20cb4bc7b3 186 Gene3D G3DSA:1.10.10.10 116 178 8.2E-13 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_17495 8cca931eac91a0b2f0fa3a20cb4bc7b3 186 SUPERFAMILY SSF88946 11 92 5.89E-18 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 MB46_17495 8cca931eac91a0b2f0fa3a20cb4bc7b3 186 Pfam PF04542 Sigma-70 region 2 15 81 1.2E-12 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 MB46_17495 8cca931eac91a0b2f0fa3a20cb4bc7b3 186 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 12 175 5.7E-17 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 MB46_09790 198ed1d32c78456595d739ffdbce88d6 334 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 148 189 1.6E-4 T 14-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 MB46_09790 198ed1d32c78456595d739ffdbce88d6 334 Gene3D G3DSA:3.30.360.10 124 309 8.6E-59 T 14-10-2018 MB46_09790 198ed1d32c78456595d739ffdbce88d6 334 SUPERFAMILY SSF51735 4 136 2.76E-34 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_09790 198ed1d32c78456595d739ffdbce88d6 334 Gene3D G3DSA:3.40.50.720 4 290 8.6E-59 T 14-10-2018 MB46_09790 198ed1d32c78456595d739ffdbce88d6 334 SUPERFAMILY SSF55347 124 277 3.92E-14 T 14-10-2018 MB46_09790 198ed1d32c78456595d739ffdbce88d6 334 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 4 114 2.6E-22 T 14-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 MB46_09780 1046cc8ceeff595ce83b07fb5197e570 411 Gene3D G3DSA:3.40.640.10 63 301 2.4E-128 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MB46_09780 1046cc8ceeff595ce83b07fb5197e570 411 Pfam PF00155 Aminotransferase class I and II 51 403 2.4E-53 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MB46_09780 1046cc8ceeff595ce83b07fb5197e570 411 SUPERFAMILY SSF53383 33 407 1.1E-97 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MB46_09780 1046cc8ceeff595ce83b07fb5197e570 411 Gene3D G3DSA:3.90.1150.10 40 403 2.4E-128 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MB46_01095 bc39b5b96747a0cc94050eaef6f2623f 152 SUPERFAMILY SSF46785 12 128 1.67E-25 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_01095 bc39b5b96747a0cc94050eaef6f2623f 152 SMART SM00347 32 134 5.7E-12 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MB46_01095 bc39b5b96747a0cc94050eaef6f2623f 152 Pfam PF12802 MarR family 39 98 1.6E-11 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MB46_01095 bc39b5b96747a0cc94050eaef6f2623f 152 Gene3D G3DSA:1.10.10.10 9 149 2.9E-29 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_01095 bc39b5b96747a0cc94050eaef6f2623f 152 PRINTS PR00598 Bacterial regulatory protein MarR family signature 75 90 3.9E-5 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MB46_01095 bc39b5b96747a0cc94050eaef6f2623f 152 PRINTS PR00598 Bacterial regulatory protein MarR family signature 94 110 3.9E-5 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MB46_18765 78c1890ac19bc8e25cb2a9612364375c 310 Gene3D G3DSA:3.30.420.40 128 297 1.2E-77 T 14-10-2018 MB46_18765 78c1890ac19bc8e25cb2a9612364375c 310 Gene3D G3DSA:3.30.420.40 6 304 1.2E-77 T 14-10-2018 MB46_18765 78c1890ac19bc8e25cb2a9612364375c 310 Pfam PF00480 ROK family 5 307 1.4E-53 T 14-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 MB46_18765 78c1890ac19bc8e25cb2a9612364375c 310 SUPERFAMILY SSF53067 1 308 1.6E-53 T 14-10-2018 MB46_15725 c67462c6f618bb21ea4e9687caf7e6c1 180 Pfam PF04978 Protein of unknown function (DUF664) 15 164 9.4E-40 T 14-10-2018 IPR007061 Protein of unknown function DUF664 MB46_15725 c67462c6f618bb21ea4e9687caf7e6c1 180 Gene3D G3DSA:1.20.120.450 2 165 2.5E-32 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes MB46_15725 c67462c6f618bb21ea4e9687caf7e6c1 180 SUPERFAMILY SSF109854 9 163 1.47E-28 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes MB46_14760 09f3158dea30f4a1b433f68b81fb2de7 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 70 81 6.4E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_14760 09f3158dea30f4a1b433f68b81fb2de7 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 120 136 6.4E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_14760 09f3158dea30f4a1b433f68b81fb2de7 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 146 165 6.4E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_14760 09f3158dea30f4a1b433f68b81fb2de7 243 Pfam PF00106 short chain dehydrogenase 1 186 3.1E-43 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_14760 09f3158dea30f4a1b433f68b81fb2de7 243 SUPERFAMILY SSF51735 2 238 6.75E-54 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_14760 09f3158dea30f4a1b433f68b81fb2de7 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 126 134 2.3E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_14760 09f3158dea30f4a1b433f68b81fb2de7 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 70 81 2.3E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_14760 09f3158dea30f4a1b433f68b81fb2de7 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 146 165 2.3E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_14760 09f3158dea30f4a1b433f68b81fb2de7 243 Gene3D G3DSA:3.40.50.720 1 243 6.1E-58 T 14-10-2018 MB46_16670 be13336a2cf41fc19cffacd4b2720399 645 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 167 270 3.5E-19 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MB46_16670 be13336a2cf41fc19cffacd4b2720399 645 SUPERFAMILY SSF56645 74 295 1.57E-55 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 MB46_16670 be13336a2cf41fc19cffacd4b2720399 645 Gene3D G3DSA:1.10.540.10 51 165 1.9E-126 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 MB46_16670 be13336a2cf41fc19cffacd4b2720399 645 Gene3D G3DSA:1.20.140.10 495 606 5.7E-14 T 14-10-2018 MB46_16670 be13336a2cf41fc19cffacd4b2720399 645 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 282 440 3.1E-30 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MB46_16670 be13336a2cf41fc19cffacd4b2720399 645 SUPERFAMILY SSF47203 282 441 1.06E-34 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 MB46_16670 be13336a2cf41fc19cffacd4b2720399 645 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 55 163 3.7E-19 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MB46_16670 be13336a2cf41fc19cffacd4b2720399 645 Gene3D G3DSA:2.40.110.10 166 281 1.9E-126 T 14-10-2018 MB46_16670 be13336a2cf41fc19cffacd4b2720399 645 Gene3D G3DSA:1.20.140.10 282 438 1.9E-126 T 14-10-2018 MB46_15945 90f90798ae8573747a1cb8a186fdf02a 300 Gene3D G3DSA:1.10.3720.10 23 293 1.5E-50 T 14-10-2018 IPR035906 MetI-like superfamily MB46_15945 90f90798ae8573747a1cb8a186fdf02a 300 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 92 291 8.9E-16 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_15945 90f90798ae8573747a1cb8a186fdf02a 300 SUPERFAMILY SSF161098 22 290 2.99E-52 T 14-10-2018 IPR035906 MetI-like superfamily MB46_16310 e138b423d50dc34674ab0a8891844e45 149 SUPERFAMILY SSF55653 60 148 2.22E-22 T 14-10-2018 IPR036791 Ribosomal protein L9, C-terminal domain superfamily MB46_16310 e138b423d50dc34674ab0a8891844e45 149 SUPERFAMILY SSF55658 3 57 3.49E-16 T 14-10-2018 IPR009027 Ribosomal protein L9/RNase H1, N-terminal MB46_16310 e138b423d50dc34674ab0a8891844e45 149 Gene3D G3DSA:3.10.430.100 62 149 1.3E-23 T 14-10-2018 IPR036791 Ribosomal protein L9, C-terminal domain superfamily MB46_16310 e138b423d50dc34674ab0a8891844e45 149 ProSitePatterns PS00651 Ribosomal protein L9 signature. 14 41 - T 14-10-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_16310 e138b423d50dc34674ab0a8891844e45 149 Pfam PF01281 Ribosomal protein L9, N-terminal domain 3 47 6.0E-18 T 14-10-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_16310 e138b423d50dc34674ab0a8891844e45 149 TIGRFAM TIGR00158 L9: ribosomal protein bL9 3 148 5.9E-37 T 14-10-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 MB46_16310 e138b423d50dc34674ab0a8891844e45 149 Pfam PF03948 Ribosomal protein L9, C-terminal domain 64 148 8.9E-25 T 14-10-2018 IPR020069 Ribosomal protein L9, C-terminal MB46_16310 e138b423d50dc34674ab0a8891844e45 149 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 2 149 23.418 T 14-10-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 MB46_16310 e138b423d50dc34674ab0a8891844e45 149 Gene3D G3DSA:3.40.5.10 2 52 1.7E-17 T 14-10-2018 IPR036935 Ribosomal protein L9, N-terminal domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_16935 8c3ad10031b145fdd36d1f5a452d9ee5 992 Pfam PF13244 Domain of unknown function (DUF4040) 620 683 3.5E-18 T 14-10-2018 IPR025383 Domain of unknown function DUF4040 MB46_16935 8c3ad10031b145fdd36d1f5a452d9ee5 992 Pfam PF00361 Proton-conducting membrane transporter 127 406 7.5E-65 T 14-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MB46_16935 8c3ad10031b145fdd36d1f5a452d9ee5 992 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 312 324 5.3E-33 T 14-10-2018 MB46_16935 8c3ad10031b145fdd36d1f5a452d9ee5 992 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 104 124 5.3E-33 T 14-10-2018 MB46_16935 8c3ad10031b145fdd36d1f5a452d9ee5 992 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 222 243 5.3E-33 T 14-10-2018 MB46_16935 8c3ad10031b145fdd36d1f5a452d9ee5 992 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 151 172 5.3E-33 T 14-10-2018 MB46_16935 8c3ad10031b145fdd36d1f5a452d9ee5 992 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 75 100 5.3E-33 T 14-10-2018 MB46_16935 8c3ad10031b145fdd36d1f5a452d9ee5 992 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 244 270 5.3E-33 T 14-10-2018 MB46_16935 8c3ad10031b145fdd36d1f5a452d9ee5 992 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 835 957 2.2E-27 T 14-10-2018 IPR007182 Na+/H+ antiporter MnhB subunit-related protein MB46_16935 8c3ad10031b145fdd36d1f5a452d9ee5 992 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 61 109 1.2E-7 T 14-10-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MB46_10605 6c30af8e00c6ec125d5ee1e0d5bef137 242 Gene3D G3DSA:1.10.10.10 157 234 4.6E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_10605 6c30af8e00c6ec125d5ee1e0d5bef137 242 SUPERFAMILY SSF55811 46 160 7.7E-27 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 MB46_10605 6c30af8e00c6ec125d5ee1e0d5bef137 242 Pfam PF00293 NUDIX domain 46 145 3.2E-8 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MB46_10605 6c30af8e00c6ec125d5ee1e0d5bef137 242 Gene3D G3DSA:3.90.79.10 10 153 5.9E-31 T 14-10-2018 MB46_10605 6c30af8e00c6ec125d5ee1e0d5bef137 242 SUPERFAMILY SSF46785 165 229 6.71E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_04710 e654ac787ee80bf0d88d09f859942173 290 Gene3D G3DSA:1.10.287.90 44 125 7.1E-13 T 14-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MB46_04710 e654ac787ee80bf0d88d09f859942173 290 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 200 248 - T 14-10-2018 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MB46_04710 e654ac787ee80bf0d88d09f859942173 290 PRINTS PR01166 Cytochrome c oxidase subunit II signature 219 236 2.6E-11 T 14-10-2018 MB46_04710 e654ac787ee80bf0d88d09f859942173 290 PRINTS PR01166 Cytochrome c oxidase subunit II signature 237 254 2.6E-11 T 14-10-2018 MB46_04710 e654ac787ee80bf0d88d09f859942173 290 PRINTS PR01166 Cytochrome c oxidase subunit II signature 199 219 2.6E-11 T 14-10-2018 MB46_04710 e654ac787ee80bf0d88d09f859942173 290 PRINTS PR01166 Cytochrome c oxidase subunit II signature 132 151 2.6E-11 T 14-10-2018 MB46_04710 e654ac787ee80bf0d88d09f859942173 290 PRINTS PR01166 Cytochrome c oxidase subunit II signature 97 109 2.6E-11 T 14-10-2018 MB46_04710 e654ac787ee80bf0d88d09f859942173 290 SUPERFAMILY SSF81464 26 120 1.59E-16 T 14-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MB46_04710 e654ac787ee80bf0d88d09f859942173 290 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 137 254 2.5E-16 T 14-10-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MB46_04710 e654ac787ee80bf0d88d09f859942173 290 SUPERFAMILY SSF49503 130 273 8.47E-38 T 14-10-2018 IPR008972 Cupredoxin MB46_04710 e654ac787ee80bf0d88d09f859942173 290 Gene3D G3DSA:2.60.40.420 126 288 1.9E-40 T 14-10-2018 IPR008972 Cupredoxin MB46_04710 e654ac787ee80bf0d88d09f859942173 290 TIGRFAM TIGR02866 CoxB: cytochrome c oxidase, subunit II 51 264 3.5E-47 T 14-10-2018 IPR014222 Cytochrome c oxidase, subunit II GO:0016021|GO:0016491 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MB46_16780 5c396e777f44b7db39298a7192c7f9ec 382 SUPERFAMILY SSF47203 230 380 2.26E-45 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 MB46_16780 5c396e777f44b7db39298a7192c7f9ec 382 Gene3D G3DSA:1.20.140.10 240 382 8.3E-44 T 14-10-2018 MB46_16780 5c396e777f44b7db39298a7192c7f9ec 382 Gene3D G3DSA:2.40.110.10 122 239 1.7E-40 T 14-10-2018 MB46_16780 5c396e777f44b7db39298a7192c7f9ec 382 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 118 9.2E-28 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MB46_16780 5c396e777f44b7db39298a7192c7f9ec 382 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 123 220 1.8E-26 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MB46_16780 5c396e777f44b7db39298a7192c7f9ec 382 Gene3D G3DSA:1.10.540.10 1 119 2.2E-30 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 MB46_16780 5c396e777f44b7db39298a7192c7f9ec 382 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 240 380 1.7E-39 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MB46_16780 5c396e777f44b7db39298a7192c7f9ec 382 SUPERFAMILY SSF56645 5 244 2.23E-75 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 MB46_16780 5c396e777f44b7db39298a7192c7f9ec 382 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 339 358 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 MB46_16985 56147f0c2f115e94b110256822c5c21f 469 Gene3D G3DSA:3.40.190.10 37 464 4.0E-64 T 14-10-2018 MB46_16985 56147f0c2f115e94b110256822c5c21f 469 Pfam PF01547 Bacterial extracellular solute-binding protein 62 377 1.1E-26 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein MB46_16985 56147f0c2f115e94b110256822c5c21f 469 SUPERFAMILY SSF53850 45 464 1.43E-57 T 14-10-2018 MB46_07045 386f173f2e331ae61b2a31560d568725 321 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 284 299 9.0E-6 T 14-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 MB46_07045 386f173f2e331ae61b2a31560d568725 321 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 299 315 9.0E-6 T 14-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 MB46_07045 386f173f2e331ae61b2a31560d568725 321 SMART SM00342 230 315 5.2E-25 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MB46_07045 386f173f2e331ae61b2a31560d568725 321 Pfam PF14525 AraC-binding-like domain 22 196 1.1E-39 T 14-10-2018 IPR035418 Transcription regulator HTH, AraC- type, ligand binding domain-like MB46_07045 386f173f2e331ae61b2a31560d568725 321 Gene3D G3DSA:1.10.10.60 210 321 4.6E-29 T 14-10-2018 MB46_07045 386f173f2e331ae61b2a31560d568725 321 Pfam PF12833 Helix-turn-helix domain 237 315 2.3E-23 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MB46_07045 386f173f2e331ae61b2a31560d568725 321 SUPERFAMILY SSF46689 265 315 5.38E-9 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MB46_18105 f5197e9063f517d2c54417321ea0ca54 334 Gene3D G3DSA:3.90.25.10 189 320 3.1E-86 T 14-10-2018 MB46_18105 f5197e9063f517d2c54417321ea0ca54 334 SUPERFAMILY SSF51735 8 324 4.35E-84 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_18105 f5197e9063f517d2c54417321ea0ca54 334 Pfam PF16363 GDP-mannose 4,6 dehydratase 16 314 1.2E-66 T 14-10-2018 IPR016040 NAD(P)-binding domain MB46_18105 f5197e9063f517d2c54417321ea0ca54 334 Gene3D G3DSA:3.40.50.720 16 310 3.1E-86 T 14-10-2018 MB46_03400 e590fefac873d2cb0b3af30b1c9a649e 70 Pfam PF12728 Helix-turn-helix domain 15 64 1.2E-8 T 14-10-2018 MB46_03400 e590fefac873d2cb0b3af30b1c9a649e 70 SUPERFAMILY SSF46955 15 64 6.23E-7 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily MB46_11030 568093ed8f611ce1b584093c6d9f8e16 142 Pfam PF01230 HIT domain 11 100 4.3E-19 T 14-10-2018 IPR001310 Histidine triad (HIT) protein MB46_11030 568093ed8f611ce1b584093c6d9f8e16 142 PRINTS PR00332 Histidine triad family signature 4 20 1.2E-11 T 14-10-2018 IPR001310 Histidine triad (HIT) protein MB46_11030 568093ed8f611ce1b584093c6d9f8e16 142 PRINTS PR00332 Histidine triad family signature 25 43 1.2E-11 T 14-10-2018 IPR001310 Histidine triad (HIT) protein MB46_11030 568093ed8f611ce1b584093c6d9f8e16 142 PRINTS PR00332 Histidine triad family signature 87 97 1.2E-11 T 14-10-2018 IPR001310 Histidine triad (HIT) protein MB46_11030 568093ed8f611ce1b584093c6d9f8e16 142 SUPERFAMILY SSF54197 3 131 6.5E-30 T 14-10-2018 IPR036265 HIT-like superfamily MB46_11030 568093ed8f611ce1b584093c6d9f8e16 142 Gene3D G3DSA:3.30.428.10 2 133 2.8E-32 T 14-10-2018 IPR036265 HIT-like superfamily MB46_02155 48a47335bfe47765a2b3badeff6a40b7 154 Gene3D G3DSA:1.10.10.10 9 87 1.0E-15 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_02155 48a47335bfe47765a2b3badeff6a40b7 154 Gene3D G3DSA:3.30.1490.190 90 146 1.3E-11 T 14-10-2018 MB46_02155 48a47335bfe47765a2b3badeff6a40b7 154 Pfam PF01475 Ferric uptake regulator family 17 108 3.2E-19 T 14-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 MB46_02155 48a47335bfe47765a2b3badeff6a40b7 154 SUPERFAMILY SSF46785 10 138 1.13E-28 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_10060 4b2fac1fc49fd6c30d81da2065f5d176 459 Pfam PF03441 FAD binding domain of DNA photolyase 275 431 2.4E-66 T 14-10-2018 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-400253 MB46_10060 4b2fac1fc49fd6c30d81da2065f5d176 459 Gene3D G3DSA:1.10.579.10 293 459 5.0E-64 T 14-10-2018 MB46_10060 4b2fac1fc49fd6c30d81da2065f5d176 459 SUPERFAMILY SSF48173 190 458 3.53E-95 T 14-10-2018 IPR036134 Cryptochrome/DNA photolyase, FAD-binding domain-like superfamily Reactome: R-HSA-400253 MB46_10060 4b2fac1fc49fd6c30d81da2065f5d176 459 PRINTS PR00147 DNA photolyase signature 139 155 1.8E-21 T 14-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 MB46_10060 4b2fac1fc49fd6c30d81da2065f5d176 459 PRINTS PR00147 DNA photolyase signature 389 403 1.8E-21 T 14-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 MB46_10060 4b2fac1fc49fd6c30d81da2065f5d176 459 PRINTS PR00147 DNA photolyase signature 350 368 1.8E-21 T 14-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 MB46_10060 4b2fac1fc49fd6c30d81da2065f5d176 459 PRINTS PR00147 DNA photolyase signature 330 346 1.8E-21 T 14-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 MB46_10060 4b2fac1fc49fd6c30d81da2065f5d176 459 ProSitePatterns PS00691 DNA photolyases class 1 signature 2. 350 369 - T 14-10-2018 IPR018394 Cryptochrome/DNA photolyase class 1, conserved site, C-terminal MB46_10060 4b2fac1fc49fd6c30d81da2065f5d176 459 Gene3D G3DSA:3.40.50.620 5 204 3.5E-88 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MB46_10060 4b2fac1fc49fd6c30d81da2065f5d176 459 Gene3D G3DSA:1.25.40.80 128 289 3.5E-88 T 14-10-2018 MB46_10060 4b2fac1fc49fd6c30d81da2065f5d176 459 SUPERFAMILY SSF52425 3 166 7.19E-53 T 14-10-2018 IPR036155 Cryptochrome/photolyase, N-terminal domain superfamily Reactome: R-HSA-400253 MB46_10060 4b2fac1fc49fd6c30d81da2065f5d176 459 Pfam PF00875 DNA photolyase 4 165 1.7E-48 T 14-10-2018 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-400253 MB46_18515 897bcf1d87a184459164c3a8f189134a 119 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 110 4.8E-6 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MB46_18515 897bcf1d87a184459164c3a8f189134a 119 SUPERFAMILY SSF54593 1 116 3.71E-18 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MB46_18515 897bcf1d87a184459164c3a8f189134a 119 Gene3D G3DSA:3.10.180.10 3 118 2.4E-28 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MB46_00770 c33ff5e6b9186c6f7087a114470ae36a 476 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 17 31 - T 14-10-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site MB46_00770 c33ff5e6b9186c6f7087a114470ae36a 476 SUPERFAMILY SSF51445 9 468 1.67E-156 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily MB46_00770 c33ff5e6b9186c6f7087a114470ae36a 476 Gene3D G3DSA:3.20.20.80 11 476 3.2E-155 T 14-10-2018 MB46_00770 c33ff5e6b9186c6f7087a114470ae36a 476 PRINTS PR00131 Glycosyl hydrolase family 1 signature 391 402 1.6E-15 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 MB46_00770 c33ff5e6b9186c6f7087a114470ae36a 476 PRINTS PR00131 Glycosyl hydrolase family 1 signature 367 375 1.6E-15 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 MB46_00770 c33ff5e6b9186c6f7087a114470ae36a 476 PRINTS PR00131 Glycosyl hydrolase family 1 signature 437 449 1.6E-15 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 MB46_00770 c33ff5e6b9186c6f7087a114470ae36a 476 PRINTS PR00131 Glycosyl hydrolase family 1 signature 412 429 1.6E-15 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 MB46_00770 c33ff5e6b9186c6f7087a114470ae36a 476 PRINTS PR00131 Glycosyl hydrolase family 1 signature 302 316 1.6E-15 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 MB46_00770 c33ff5e6b9186c6f7087a114470ae36a 476 Pfam PF00232 Glycosyl hydrolase family 1 11 472 1.5E-143 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 MB46_00770 c33ff5e6b9186c6f7087a114470ae36a 476 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 367 375 - T 14-10-2018 IPR018120 Glycoside hydrolase family 1, active site MB46_02610 487c1171ec41eca754550f2907b66cfb 159 Pfam PF04892 VanZ like family 14 130 1.1E-17 T 14-10-2018 IPR006976 VanZ-like MB46_10750 7c984fd8a518a3876d4645c3cf04d8c3 434 SUPERFAMILY SSF54675 1 128 1.92E-40 T 14-10-2018 MB46_10750 7c984fd8a518a3876d4645c3cf04d8c3 434 PIRSF PIRSF000484 1 433 5.2E-91 T 14-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 MB46_10750 7c984fd8a518a3876d4645c3cf04d8c3 434 Gene3D G3DSA:3.20.20.70 142 301 3.6E-101 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MB46_10750 7c984fd8a518a3876d4645c3cf04d8c3 434 SUPERFAMILY SSF51690 130 427 2.06E-78 T 14-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 MB46_10750 7c984fd8a518a3876d4645c3cf04d8c3 434 Gene3D G3DSA:3.20.140.10 1 365 3.6E-101 T 14-10-2018 MB46_10750 7c984fd8a518a3876d4645c3cf04d8c3 434 TIGRFAM TIGR01513 NAPRTase_put: nicotinate phosphoribosyltransferase 1 372 5.6E-119 T 14-10-2018 IPR006405 Nicotinate phosphoribosyltransferase pncB-type GO:0004516|GO:0019358 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264|Reactome: R-HSA-6798695 MB46_17535 ab1bf0c1e4f73b4423bc361a740de770 428 Gene3D G3DSA:3.40.190.10 148 415 1.1E-111 T 14-10-2018 MB46_17535 ab1bf0c1e4f73b4423bc361a740de770 428 SUPERFAMILY SSF53850 22 425 1.66E-50 T 14-10-2018 MB46_17535 ab1bf0c1e4f73b4423bc361a740de770 428 Pfam PF13416 Bacterial extracellular solute-binding protein 59 349 5.7E-22 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein MB46_17535 ab1bf0c1e4f73b4423bc361a740de770 428 Gene3D G3DSA:3.40.190.10 43 371 1.1E-111 T 14-10-2018 MB46_05550 d52bab51104b9cf54dac5b9f909c2a8f 184 Pfam PF13302 Acetyltransferase (GNAT) domain 8 146 3.9E-33 T 14-10-2018 IPR000182 GNAT domain MB46_05550 d52bab51104b9cf54dac5b9f909c2a8f 184 SUPERFAMILY SSF55729 7 171 2.2E-45 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase MB46_05550 d52bab51104b9cf54dac5b9f909c2a8f 184 Gene3D G3DSA:3.40.630.30 4 181 1.8E-49 T 14-10-2018 MB46_14740 45f6a76302e7487bbb049b72cd9e94e5 165 TIGRFAM TIGR03180 UraD_2: OHCU decarboxylase 6 162 1.8E-53 T 14-10-2018 IPR017595 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase, type 2 MB46_14740 45f6a76302e7487bbb049b72cd9e94e5 165 Pfam PF09349 OHCU decarboxylase 10 160 4.4E-34 T 14-10-2018 IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 MB46_14740 45f6a76302e7487bbb049b72cd9e94e5 165 Gene3D G3DSA:1.10.3330.10 1 164 1.2E-47 T 14-10-2018 IPR036778 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase superfamily KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 MB46_14740 45f6a76302e7487bbb049b72cd9e94e5 165 SUPERFAMILY SSF158694 3 162 1.44E-40 T 14-10-2018 IPR036778 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase superfamily KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 MB46_08055 350c55cbe4d93a38905b654ee9e8cf67 575 SUPERFAMILY SSF47005 264 306 1.14E-11 T 14-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 MB46_08055 350c55cbe4d93a38905b654ee9e8cf67 575 Pfam PF00364 Biotin-requiring enzyme 4 76 7.5E-21 T 14-10-2018 IPR000089 Biotin/lipoyl attachment MB46_08055 350c55cbe4d93a38905b654ee9e8cf67 575 Pfam PF00364 Biotin-requiring enzyme 129 201 1.9E-19 T 14-10-2018 IPR000089 Biotin/lipoyl attachment MB46_08055 350c55cbe4d93a38905b654ee9e8cf67 575 Gene3D G3DSA:3.30.559.10 318 572 2.9E-81 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 MB46_08055 350c55cbe4d93a38905b654ee9e8cf67 575 SUPERFAMILY SSF51230 3 92 2.22E-26 T 14-10-2018 IPR011053 Single hybrid motif MB46_08055 350c55cbe4d93a38905b654ee9e8cf67 575 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 339 566 3.1E-75 T 14-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 MB46_08055 350c55cbe4d93a38905b654ee9e8cf67 575 Gene3D G3DSA:2.40.50.100 1 102 6.6E-27 T 14-10-2018 MB46_08055 350c55cbe4d93a38905b654ee9e8cf67 575 Gene3D G3DSA:2.40.50.100 122 225 2.9E-25 T 14-10-2018 MB46_08055 350c55cbe4d93a38905b654ee9e8cf67 575 Pfam PF02817 e3 binding domain 270 302 1.2E-13 T 14-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 MB46_08055 350c55cbe4d93a38905b654ee9e8cf67 575 SUPERFAMILY SSF52777 331 566 5.34E-76 T 14-10-2018 MB46_08055 350c55cbe4d93a38905b654ee9e8cf67 575 SUPERFAMILY SSF51230 127 221 2.62E-26 T 14-10-2018 IPR011053 Single hybrid motif MB46_08055 350c55cbe4d93a38905b654ee9e8cf67 575 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 152 181 - T 14-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 MB46_08055 350c55cbe4d93a38905b654ee9e8cf67 575 Gene3D G3DSA:4.10.320.10 264 308 1.6E-15 T 14-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 MB46_08055 350c55cbe4d93a38905b654ee9e8cf67 575 TIGRFAM TIGR02927 SucB_Actino: 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase 1 575 7.7E-252 T 14-10-2018 IPR014276 2-oxoglutarate dehydrogenase, E2 component KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00620+2.3.1.12 MB46_08055 350c55cbe4d93a38905b654ee9e8cf67 575 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 14-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 MB46_05130 474082ac18bb585bb28ee724db018e03 267 Gene3D G3DSA:1.10.10.10 15 120 8.0E-11 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_05130 474082ac18bb585bb28ee724db018e03 267 SUPERFAMILY SSF46785 18 208 1.4E-24 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_05130 474082ac18bb585bb28ee724db018e03 267 Pfam PF12840 Helix-turn-helix domain 18 64 3.1E-6 T 14-10-2018 MB46_13625 f833a72dbdb968090d0a1f2023fe0b1a 430 Gene3D G3DSA:3.40.190.10 36 426 1.1E-83 T 14-10-2018 MB46_13625 f833a72dbdb968090d0a1f2023fe0b1a 430 SUPERFAMILY SSF53850 20 428 4.94E-58 T 14-10-2018 MB46_13625 f833a72dbdb968090d0a1f2023fe0b1a 430 Pfam PF13416 Bacterial extracellular solute-binding protein 61 354 2.7E-31 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein MB46_10155 e2dd8926aff4237b964150e607f924f6 829 Pfam PF12704 MacB-like periplasmic core domain 19 228 5.8E-10 T 14-10-2018 IPR025857 MacB-like periplasmic core domain MB46_10155 e2dd8926aff4237b964150e607f924f6 829 Pfam PF02687 FtsX-like permease family 730 822 6.3E-13 T 14-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 MB46_10155 e2dd8926aff4237b964150e607f924f6 829 Pfam PF02687 FtsX-like permease family 290 380 8.6E-13 T 14-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 MB46_13120 0e41fb1e0a38d800875b507b60d5e2eb 320 SUPERFAMILY SSF161098 33 317 3.46E-44 T 14-10-2018 IPR035906 MetI-like superfamily MB46_13120 0e41fb1e0a38d800875b507b60d5e2eb 320 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 128 318 7.4E-14 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_13120 0e41fb1e0a38d800875b507b60d5e2eb 320 Gene3D G3DSA:1.10.3720.10 79 320 1.2E-51 T 14-10-2018 IPR035906 MetI-like superfamily MB46_04330 4f0af09a50b8155dcc045754f063403f 270 SUPERFAMILY SSF55781 83 261 2.16E-53 T 14-10-2018 MB46_04330 4f0af09a50b8155dcc045754f063403f 270 SUPERFAMILY SSF46785 15 91 2.73E-11 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_04330 4f0af09a50b8155dcc045754f063403f 270 SMART SM00346 14 107 2.3E-20 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 MB46_04330 4f0af09a50b8155dcc045754f063403f 270 Gene3D G3DSA:3.30.450.40 89 268 1.5E-62 T 14-10-2018 IPR029016 GAF-like domain superfamily MB46_04330 4f0af09a50b8155dcc045754f063403f 270 Pfam PF01614 Bacterial transcriptional regulator 134 258 1.8E-37 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal MB46_04330 4f0af09a50b8155dcc045754f063403f 270 Gene3D G3DSA:1.10.10.10 12 88 3.2E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_04330 4f0af09a50b8155dcc045754f063403f 270 Pfam PF09339 IclR helix-turn-helix domain 16 69 1.3E-9 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 MB46_07800 3d51476b0a7479370b1e6f8f51932dad 165 PIRSF PIRSF006181 5 164 3.4E-49 T 14-10-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC MB46_07800 3d51476b0a7479370b1e6f8f51932dad 165 Gene3D G3DSA:3.90.960.10 3 162 2.2E-56 T 14-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 MB46_07800 3d51476b0a7479370b1e6f8f51932dad 165 Pfam PF04073 Aminoacyl-tRNA editing domain 37 151 5.2E-26 T 14-10-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 MB46_07800 3d51476b0a7479370b1e6f8f51932dad 165 TIGRFAM TIGR00011 YbaK_EbsC: Cys-tRNA(Pro) deacylase 10 160 2.0E-52 T 14-10-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC MB46_07800 3d51476b0a7479370b1e6f8f51932dad 165 SUPERFAMILY SSF55826 10 160 3.4E-40 T 14-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 MB46_08865 93aa9be8191fd7c98e40592968def6b9 328 Gene3D G3DSA:3.40.50.410 91 290 8.3E-28 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily MB46_08865 93aa9be8191fd7c98e40592968def6b9 328 Pfam PF00092 von Willebrand factor type A domain 94 283 3.4E-9 T 14-10-2018 IPR002035 von Willebrand factor, type A MB46_08865 93aa9be8191fd7c98e40592968def6b9 328 SMART SM00327 92 290 9.2E-7 T 14-10-2018 IPR002035 von Willebrand factor, type A MB46_08865 93aa9be8191fd7c98e40592968def6b9 328 SUPERFAMILY SSF53300 89 287 2.23E-21 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily MB46_15160 de19a1b9484a351f29b5567c33490dc7 675 Pfam PF00664 ABC transporter transmembrane region 68 377 2.7E-61 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 MB46_15160 de19a1b9484a351f29b5567c33490dc7 675 SUPERFAMILY SSF90123 50 408 1.11E-83 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MB46_15160 de19a1b9484a351f29b5567c33490dc7 675 SUPERFAMILY SSF52540 413 660 1.6E-89 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_15160 de19a1b9484a351f29b5567c33490dc7 675 Pfam PF00005 ABC transporter 441 589 3.8E-33 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_15160 de19a1b9484a351f29b5567c33490dc7 675 Gene3D G3DSA:3.40.50.300 420 670 7.6E-91 T 14-10-2018 MB46_15160 de19a1b9484a351f29b5567c33490dc7 675 ProSitePatterns PS00211 ABC transporters family signature. 561 575 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_15160 de19a1b9484a351f29b5567c33490dc7 675 SMART SM00382 449 621 3.2E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_00545 594ae140e46eeebda2412f5252f94c49 333 Gene3D G3DSA:3.20.20.330 4 315 7.5E-112 T 14-10-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 MB46_00545 594ae140e46eeebda2412f5252f94c49 333 SUPERFAMILY SSF82282 12 319 2.75E-87 T 14-10-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 MB46_00545 594ae140e46eeebda2412f5252f94c49 333 Pfam PF02574 Homocysteine S-methyltransferase 19 315 3.3E-78 T 14-10-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 MB46_00545 594ae140e46eeebda2412f5252f94c49 333 PIRSF PIRSF037505 278 330 0.056 T 14-10-2018 IPR017226 Betaine-homocysteine S-methyltransferase, BHMT GO:0005737|GO:0008270|GO:0009086|GO:0047150 Reactome: R-HSA-1614635 MB46_00545 594ae140e46eeebda2412f5252f94c49 333 PIRSF PIRSF037505 4 246 7.6E-6 T 14-10-2018 IPR017226 Betaine-homocysteine S-methyltransferase, BHMT GO:0005737|GO:0008270|GO:0009086|GO:0047150 Reactome: R-HSA-1614635 MB46_02135 27e700054c668b8afd69476c41129983 443 Pfam PF02562 PhoH-like protein 234 438 1.4E-53 T 14-10-2018 IPR003714 PhoH-like protein GO:0005524 MB46_02135 27e700054c668b8afd69476c41129983 443 Pfam PF13638 PIN domain 19 157 2.6E-28 T 14-10-2018 IPR002716 PIN domain MB46_02135 27e700054c668b8afd69476c41129983 443 Gene3D G3DSA:3.40.50.1010 14 160 4.7E-17 T 14-10-2018 MB46_02135 27e700054c668b8afd69476c41129983 443 SMART SM00670 17 144 5.8E-12 T 14-10-2018 IPR002716 PIN domain MB46_02135 27e700054c668b8afd69476c41129983 443 SUPERFAMILY SSF88723 18 158 4.51E-7 T 14-10-2018 IPR029060 PIN-like domain superfamily MB46_02135 27e700054c668b8afd69476c41129983 443 Gene3D G3DSA:3.40.50.300 232 439 1.0E-51 T 14-10-2018 MB46_02135 27e700054c668b8afd69476c41129983 443 SUPERFAMILY SSF52540 232 394 5.41E-19 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_10610 409dd4e76d937f99bf00d4c9e73a726f 295 SUPERFAMILY SSF63380 14 146 7.49E-12 T 14-10-2018 IPR017938 Riboflavin synthase-like beta-barrel MB46_10610 409dd4e76d937f99bf00d4c9e73a726f 295 Gene3D G3DSA:3.40.50.80 159 295 7.2E-22 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain MB46_10610 409dd4e76d937f99bf00d4c9e73a726f 295 Gene3D G3DSA:2.40.30.10 10 149 2.9E-34 T 14-10-2018 MB46_10610 409dd4e76d937f99bf00d4c9e73a726f 295 Pfam PF08021 Siderophore-interacting FAD-binding domain 26 149 5.9E-34 T 14-10-2018 IPR013113 FAD-binding 9, siderophore-interacting MB46_10610 409dd4e76d937f99bf00d4c9e73a726f 295 Pfam PF04954 Siderophore-interacting protein 165 290 2.9E-23 T 14-10-2018 IPR007037 Siderophore-interacting protein, C-terminal domain MB46_06035 39867fb91c4bf6139a29d2488935ad36 374 SUPERFAMILY SSF55347 134 294 5.4E-30 T 14-10-2018 MB46_06035 39867fb91c4bf6139a29d2488935ad36 374 Gene3D G3DSA:3.40.50.720 5 132 1.9E-28 T 14-10-2018 MB46_06035 39867fb91c4bf6139a29d2488935ad36 374 Gene3D G3DSA:3.30.360.10 133 349 2.9E-33 T 14-10-2018 MB46_06035 39867fb91c4bf6139a29d2488935ad36 374 SUPERFAMILY SSF51735 7 157 1.13E-38 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_06035 39867fb91c4bf6139a29d2488935ad36 374 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 8 123 3.4E-18 T 14-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 MB46_17910 4371db234edc3e1360af4179ece4acda 120 Pfam PF03551 Transcriptional regulator PadR-like family 16 89 3.4E-23 T 14-10-2018 IPR005149 Transcription regulator PadR, N-terminal MB46_17910 4371db234edc3e1360af4179ece4acda 120 SUPERFAMILY SSF46785 15 104 1.19E-25 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_17910 4371db234edc3e1360af4179ece4acda 120 Gene3D G3DSA:1.10.10.10 3 115 1.5E-28 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_07870 7972b977b88e4fc5d6c2eaa6c15d37e2 186 Gene3D G3DSA:2.40.380.10 51 178 7.7E-8 T 14-10-2018 IPR035930 FomD-like superfamily MB46_07870 7972b977b88e4fc5d6c2eaa6c15d37e2 186 Pfam PF04167 Protein of unknown function (DUF402) 64 134 3.3E-9 T 14-10-2018 IPR007295 Domain of unknown function DUF402 MB46_07870 7972b977b88e4fc5d6c2eaa6c15d37e2 186 SUPERFAMILY SSF159234 12 172 5.1E-10 T 14-10-2018 IPR035930 FomD-like superfamily MB46_08530 cdce3321c67bd82f31268d4910fa6f3e 189 PRINTS PR01100 Shikimate kinase family signature 18 33 4.0E-17 T 14-10-2018 MB46_08530 cdce3321c67bd82f31268d4910fa6f3e 189 PRINTS PR01100 Shikimate kinase family signature 110 127 4.0E-17 T 14-10-2018 MB46_08530 cdce3321c67bd82f31268d4910fa6f3e 189 PRINTS PR01100 Shikimate kinase family signature 42 55 4.0E-17 T 14-10-2018 MB46_08530 cdce3321c67bd82f31268d4910fa6f3e 189 PRINTS PR01100 Shikimate kinase family signature 90 99 4.0E-17 T 14-10-2018 MB46_08530 cdce3321c67bd82f31268d4910fa6f3e 189 PRINTS PR01100 Shikimate kinase family signature 69 77 4.0E-17 T 14-10-2018 MB46_08530 cdce3321c67bd82f31268d4910fa6f3e 189 ProSitePatterns PS01128 Shikimate kinase signature. 70 98 - T 14-10-2018 IPR023000 Shikimate kinase, conserved site KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 MB46_08530 cdce3321c67bd82f31268d4910fa6f3e 189 Gene3D G3DSA:3.40.50.300 16 189 4.2E-45 T 14-10-2018 MB46_08530 cdce3321c67bd82f31268d4910fa6f3e 189 Pfam PF01202 Shikimate kinase 24 180 1.2E-34 T 14-10-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 MB46_08530 cdce3321c67bd82f31268d4910fa6f3e 189 Hamap MF_00109 Shikimate kinase [aroK]. 15 181 23.104 T 14-10-2018 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 MB46_08530 cdce3321c67bd82f31268d4910fa6f3e 189 SUPERFAMILY SSF52540 14 182 5.34E-22 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_00930 04e0758b407f320abaa92cca89c5164e 97 SUPERFAMILY SSF140453 3 94 1.7E-19 T 14-10-2018 IPR036689 ESAT-6-like superfamily MB46_00930 04e0758b407f320abaa92cca89c5164e 97 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 3 91 7.0E-18 T 14-10-2018 IPR010310 Type VII secretion system ESAT-6-like MB46_00930 04e0758b407f320abaa92cca89c5164e 97 Gene3D G3DSA:1.10.287.1060 1 83 1.2E-17 T 14-10-2018 MB46_00930 04e0758b407f320abaa92cca89c5164e 97 Pfam PF06013 Proteins of 100 residues with WXG 3 87 2.0E-15 T 14-10-2018 IPR010310 Type VII secretion system ESAT-6-like MB46_10200 a29e094217a81c1eb010286291ffcc40 303 Gene3D G3DSA:1.10.3720.10 58 300 2.3E-72 T 14-10-2018 IPR035906 MetI-like superfamily MB46_10200 a29e094217a81c1eb010286291ffcc40 303 SUPERFAMILY SSF160964 21 53 7.32E-5 T 14-10-2018 MB46_10200 a29e094217a81c1eb010286291ffcc40 303 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 94 297 1.1E-21 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_10200 a29e094217a81c1eb010286291ffcc40 303 SUPERFAMILY SSF161098 62 288 6.02E-63 T 14-10-2018 IPR035906 MetI-like superfamily MB46_18130 b419bb11d0511eec5c015a780df3de50 101 Gene3D G3DSA:1.10.10.10 5 100 2.1E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_18130 b419bb11d0511eec5c015a780df3de50 101 Pfam PF13601 Winged helix DNA-binding domain 18 95 4.5E-16 T 14-10-2018 IPR027395 Winged helix DNA-binding domain MB46_18130 b419bb11d0511eec5c015a780df3de50 101 SUPERFAMILY SSF46785 10 98 1.92E-10 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_18130 b419bb11d0511eec5c015a780df3de50 101 SMART SM00418 9 99 0.0083 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MB46_17565 a4716afe17cf0865cdea07e1a89bfb8b 840 SUPERFAMILY SSF69318 147 715 9.81E-25 T 14-10-2018 MB46_17565 a4716afe17cf0865cdea07e1a89bfb8b 840 Gene3D G3DSA:2.60.40.10 37 133 1.7E-27 T 14-10-2018 IPR013783 Immunoglobulin-like fold MB46_03845 bff8df99080aab8c84a89c8a38b7c401 169 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 12 158 7.0E-58 T 14-10-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MB46_03845 bff8df99080aab8c84a89c8a38b7c401 169 Hamap MF_01224_B Cyclic pyranopterin monophosphate synthase [moaC]. 10 164 35.305 T 14-10-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MB46_03845 bff8df99080aab8c84a89c8a38b7c401 169 SUPERFAMILY SSF55040 19 161 1.15E-55 T 14-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MB46_03845 bff8df99080aab8c84a89c8a38b7c401 169 Pfam PF01967 MoaC family 23 156 6.4E-52 T 14-10-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MB46_03845 bff8df99080aab8c84a89c8a38b7c401 169 Gene3D G3DSA:3.30.70.640 10 165 9.3E-63 T 14-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MB46_15390 0785ee4c6d6092bba3402fcc449051e6 333 Gene3D G3DSA:3.30.1180.20 185 333 8.3E-51 T 14-10-2018 MB46_15390 0785ee4c6d6092bba3402fcc449051e6 333 TIGRFAM TIGR02363 dhaK1: dihydroxyacetone kinase, DhaK subunit 1 329 9.9E-149 T 14-10-2018 IPR012736 Dihydroxyacetone kinase DhaK, subunit 1 KEGG: 00561+2.7.1.121 MB46_15390 0785ee4c6d6092bba3402fcc449051e6 333 Pfam PF02733 Dak1 domain 17 328 6.4E-131 T 14-10-2018 IPR004006 DhaK domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 MB46_15390 0785ee4c6d6092bba3402fcc449051e6 333 SUPERFAMILY SSF82549 11 332 6.8E-122 T 14-10-2018 MB46_15390 0785ee4c6d6092bba3402fcc449051e6 333 Gene3D G3DSA:3.40.50.10440 11 184 1.2E-64 T 14-10-2018 MB46_15505 15131e93a590e2ed420c07b0da794b43 385 TIGRFAM TIGR03883 DUF2342_F420: uncharacterized protein, coenzyme F420 biosynthesis associated 19 383 2.3E-126 T 14-10-2018 IPR022454 Conserved hypothetical protein CHP03883, F420 biosynthesis associated MB46_15505 15131e93a590e2ed420c07b0da794b43 385 SUPERFAMILY SSF55486 18 383 1.17E-94 T 14-10-2018 MB46_15505 15131e93a590e2ed420c07b0da794b43 385 TIGRFAM TIGR03624 TIGR03624: putative hydrolase 19 383 1.5E-109 T 14-10-2018 IPR018766 Zinicin-like metallopeptidase type 2 MB46_15505 15131e93a590e2ed420c07b0da794b43 385 Gene3D G3DSA:1.20.150.30 18 152 1.3E-31 T 14-10-2018 MB46_15505 15131e93a590e2ed420c07b0da794b43 385 Pfam PF10103 Zincin-like metallopeptidase 19 380 5.9E-108 T 14-10-2018 IPR018766 Zinicin-like metallopeptidase type 2 MB46_19845 3f23bd3b9793010eb93be15915b83f0f 153 SMART SM00347 28 128 2.2E-21 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MB46_19845 3f23bd3b9793010eb93be15915b83f0f 153 ProSitePatterns PS01117 MarR-type HTH domain signature. 68 101 - T 14-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site MB46_19845 3f23bd3b9793010eb93be15915b83f0f 153 Pfam PF01047 MarR family 35 93 3.1E-14 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MB46_19845 3f23bd3b9793010eb93be15915b83f0f 153 Gene3D G3DSA:1.10.10.10 1 145 4.0E-31 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_19845 3f23bd3b9793010eb93be15915b83f0f 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 52 68 7.1E-11 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MB46_19845 3f23bd3b9793010eb93be15915b83f0f 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 69 84 7.1E-11 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MB46_19845 3f23bd3b9793010eb93be15915b83f0f 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 88 104 7.1E-11 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MB46_19845 3f23bd3b9793010eb93be15915b83f0f 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 118 138 7.1E-11 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MB46_19845 3f23bd3b9793010eb93be15915b83f0f 153 SUPERFAMILY SSF46785 12 143 3.7E-30 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_01650 e34f63dc66ea6d63f38f6efb00f989b7 344 Gene3D G3DSA:1.10.3720.10 108 338 1.1E-22 T 14-10-2018 IPR035906 MetI-like superfamily MB46_01650 e34f63dc66ea6d63f38f6efb00f989b7 344 SUPERFAMILY SSF161098 114 325 6.28E-18 T 14-10-2018 IPR035906 MetI-like superfamily MB46_01650 e34f63dc66ea6d63f38f6efb00f989b7 344 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 135 342 2.1E-42 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_17205 ee635bfa4c563a66c04ee0e069ecbc5e 141 Gene3D G3DSA:3.10.400.10 2 141 1.4E-39 T 14-10-2018 MB46_17205 ee635bfa4c563a66c04ee0e069ecbc5e 141 SUPERFAMILY SSF88697 9 138 3.23E-30 T 14-10-2018 IPR015947 PUA-like superfamily MB46_17205 ee635bfa4c563a66c04ee0e069ecbc5e 141 SMART SM01022 12 138 2.6E-26 T 14-10-2018 IPR007374 ASCH domain MB46_17205 ee635bfa4c563a66c04ee0e069ecbc5e 141 Pfam PF04266 ASCH domain 19 138 1.3E-15 T 14-10-2018 IPR007374 ASCH domain MB46_17205 ee635bfa4c563a66c04ee0e069ecbc5e 141 PIRSF PIRSF021320 2 141 3.0E-39 T 14-10-2018 IPR009326 Protein of unknown function DUF984 MB46_11270 8bdfc5c2d456225d4d44c70ecb68d951 251 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 68 137 5.4E-31 T 14-10-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 MB46_11270 8bdfc5c2d456225d4d44c70ecb68d951 251 SMART SM00899 148 226 9.8E-11 T 14-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 MB46_11270 8bdfc5c2d456225d4d44c70ecb68d951 251 SUPERFAMILY SSF47979 68 139 6.67E-26 T 14-10-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 MB46_11270 8bdfc5c2d456225d4d44c70ecb68d951 251 SUPERFAMILY SSF50037 151 203 6.87E-5 T 14-10-2018 IPR008988 Transcriptional repressor, C-terminal MB46_11270 8bdfc5c2d456225d4d44c70ecb68d951 251 Gene3D G3DSA:1.10.10.10 4 140 3.1E-52 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_11270 8bdfc5c2d456225d4d44c70ecb68d951 251 Pfam PF04023 FeoA domain 149 223 9.2E-13 T 14-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 MB46_11270 8bdfc5c2d456225d4d44c70ecb68d951 251 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 8 63 1.8E-17 T 14-10-2018 IPR022687 DTXR-type HTH domain GO:0003677 MB46_11270 8bdfc5c2d456225d4d44c70ecb68d951 251 SMART SM00529 29 128 9.9E-42 T 14-10-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 MB46_11270 8bdfc5c2d456225d4d44c70ecb68d951 251 SUPERFAMILY SSF46785 8 67 2.19E-13 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_12355 7b8d80b5d063582c9a095838043d8506 524 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 432 444 - T 14-10-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site MB46_12355 7b8d80b5d063582c9a095838043d8506 524 SUPERFAMILY SSF53092 57 252 1.67E-25 T 14-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal MB46_12355 7b8d80b5d063582c9a095838043d8506 524 SMART SM01011 54 198 2.0E-34 T 14-10-2018 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 MB46_12355 7b8d80b5d063582c9a095838043d8506 524 Pfam PF00557 Metallopeptidase family M24 258 496 6.5E-46 T 14-10-2018 IPR000994 Peptidase M24 MB46_12355 7b8d80b5d063582c9a095838043d8506 524 Gene3D G3DSA:3.40.350.10 56 237 3.2E-16 T 14-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal MB46_12355 7b8d80b5d063582c9a095838043d8506 524 Gene3D G3DSA:3.90.230.10 252 523 2.6E-72 T 14-10-2018 MB46_12355 7b8d80b5d063582c9a095838043d8506 524 Pfam PF05195 Aminopeptidase P, N-terminal domain 61 192 4.4E-19 T 14-10-2018 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 MB46_12355 7b8d80b5d063582c9a095838043d8506 524 SUPERFAMILY SSF55920 253 520 1.57E-60 T 14-10-2018 IPR036005 Creatinase/aminopeptidase-like MB46_10355 3fef5bf73274c873e2108616b1f0a92f 451 Gene3D G3DSA:3.40.50.300 2 181 3.5E-12 T 14-10-2018 MB46_07165 e294791e6cda9db249625bfca811404a 312 SUPERFAMILY SSF55729 202 302 4.97E-13 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase MB46_07165 e294791e6cda9db249625bfca811404a 312 Gene3D G3DSA:3.40.630.30 2 310 3.8E-17 T 14-10-2018 MB46_05025 8aa2a76c49e8f770886894e933e902c7 226 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 177 8.2E-18 T 14-10-2018 MB46_05025 8aa2a76c49e8f770886894e933e902c7 226 Gene3D G3DSA:3.40.50.1000 64 197 3.9E-46 T 14-10-2018 IPR023214 HAD superfamily MB46_05025 8aa2a76c49e8f770886894e933e902c7 226 SUPERFAMILY SSF56784 6 207 1.23E-36 T 14-10-2018 IPR036412 HAD-like superfamily MB46_05025 8aa2a76c49e8f770886894e933e902c7 226 Gene3D G3DSA:1.10.150.240 1 63 3.9E-46 T 14-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 MB46_14560 ea71caee8ec6eb6c36b3751d77afa5bc 187 Pfam PF01872 RibD C-terminal domain 3 178 5.9E-21 T 14-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 MB46_14560 ea71caee8ec6eb6c36b3751d77afa5bc 187 SUPERFAMILY SSF53597 1 184 5.47E-29 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 MB46_14560 ea71caee8ec6eb6c36b3751d77afa5bc 187 Gene3D G3DSA:3.40.430.10 2 182 2.1E-35 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 MB46_17280 73fca14dc0b5cff4d0612152292c32a4 430 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 417 40.593 T 14-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MB46_17280 73fca14dc0b5cff4d0612152292c32a4 430 SUPERFAMILY SSF51246 321 416 9.94E-27 T 14-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 MB46_17280 73fca14dc0b5cff4d0612152292c32a4 430 SUPERFAMILY SSF56059 102 311 1.36E-55 T 14-10-2018 MB46_17280 73fca14dc0b5cff4d0612152292c32a4 430 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 281 288 - T 14-10-2018 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MB46_17280 73fca14dc0b5cff4d0612152292c32a4 430 Gene3D G3DSA:3.30.470.20 183 319 4.5E-53 T 14-10-2018 MB46_17280 73fca14dc0b5cff4d0612152292c32a4 430 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 323 414 1.1E-25 T 14-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MB46_17280 73fca14dc0b5cff4d0612152292c32a4 430 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 2 100 8.4E-30 T 14-10-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MB46_17280 73fca14dc0b5cff4d0612152292c32a4 430 SMART SM01209 101 287 5.3E-115 T 14-10-2018 MB46_17280 73fca14dc0b5cff4d0612152292c32a4 430 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 2 417 1.4E-147 T 14-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MB46_17280 73fca14dc0b5cff4d0612152292c32a4 430 SUPERFAMILY SSF52440 2 100 2.45E-30 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily MB46_17280 73fca14dc0b5cff4d0612152292c32a4 430 Gene3D G3DSA:3.30.1490.20 121 182 3.0E-17 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 MB46_17280 73fca14dc0b5cff4d0612152292c32a4 430 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 101 287 2.3E-67 T 14-10-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MB46_17280 73fca14dc0b5cff4d0612152292c32a4 430 Gene3D G3DSA:3.90.600.10 322 427 9.5E-30 T 14-10-2018 IPR037123 Phosphoribosylglycinamide synthetase, C-domain superfamily GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MB46_17280 73fca14dc0b5cff4d0612152292c32a4 430 Gene3D G3DSA:3.40.50.20 1 93 3.8E-30 T 14-10-2018 MB46_17280 73fca14dc0b5cff4d0612152292c32a4 430 SMART SM01210 322 417 2.0E-44 T 14-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MB46_00935 e4958566bb18f6a7866e57db45cf3912 498 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 370 484 3.2E-24 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MB46_00935 e4958566bb18f6a7866e57db45cf3912 498 SMART SM00304 195 248 2.5E-10 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MB46_00935 e4958566bb18f6a7866e57db45cf3912 498 Gene3D G3DSA:3.30.565.10 324 487 6.8E-37 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MB46_00935 e4958566bb18f6a7866e57db45cf3912 498 SUPERFAMILY SSF47384 242 323 1.29E-17 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MB46_00935 e4958566bb18f6a7866e57db45cf3912 498 Pfam PF00512 His Kinase A (phospho-acceptor) domain 257 322 1.9E-16 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MB46_00935 e4958566bb18f6a7866e57db45cf3912 498 Gene3D G3DSA:1.20.1480.50 162 251 1.4E-9 T 14-10-2018 MB46_00935 e4958566bb18f6a7866e57db45cf3912 498 SMART SM00387 370 486 8.6E-38 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MB46_00935 e4958566bb18f6a7866e57db45cf3912 498 SMART SM00388 256 323 6.7E-17 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MB46_00935 e4958566bb18f6a7866e57db45cf3912 498 SUPERFAMILY SSF158472 198 245 1.19E-7 T 14-10-2018 MB46_00935 e4958566bb18f6a7866e57db45cf3912 498 Pfam PF00672 HAMP domain 199 245 4.5E-9 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MB46_00935 e4958566bb18f6a7866e57db45cf3912 498 SUPERFAMILY SSF55874 312 486 9.43E-39 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MB46_00935 e4958566bb18f6a7866e57db45cf3912 498 Gene3D G3DSA:1.10.287.130 252 323 7.8E-22 T 14-10-2018 MB46_00935 e4958566bb18f6a7866e57db45cf3912 498 PRINTS PR00344 Bacterial sensor protein C-terminal signature 470 483 1.1E-16 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MB46_00935 e4958566bb18f6a7866e57db45cf3912 498 PRINTS PR00344 Bacterial sensor protein C-terminal signature 429 439 1.1E-16 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MB46_00935 e4958566bb18f6a7866e57db45cf3912 498 PRINTS PR00344 Bacterial sensor protein C-terminal signature 446 464 1.1E-16 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MB46_00935 e4958566bb18f6a7866e57db45cf3912 498 PRINTS PR00344 Bacterial sensor protein C-terminal signature 411 425 1.1E-16 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MB46_05420 a996620ae3f642235a2bdf31ba9d941f 457 Pfam PF03136 Pup-ligase protein 4 423 4.8E-158 T 14-10-2018 IPR004347 Pup ligase/deamidase GO:0010498|GO:0019941 MetaCyc: PWY-7893 MB46_05420 a996620ae3f642235a2bdf31ba9d941f 457 Hamap MF_02111 Pup--protein ligase [pafA]. 1 453 50.135 T 14-10-2018 IPR022279 Pup--protein ligase GO:0010498|GO:0016879|GO:0019941 MetaCyc: PWY-7893 MB46_05420 a996620ae3f642235a2bdf31ba9d941f 457 TIGRFAM TIGR03686 pupylate_PafA: Pup--protein ligase 3 453 1.4E-225 T 14-10-2018 IPR022279 Pup--protein ligase GO:0010498|GO:0016879|GO:0019941 MetaCyc: PWY-7893 MB46_05420 a996620ae3f642235a2bdf31ba9d941f 457 PIRSF PIRSF018077 1 455 3.0E-172 T 14-10-2018 IPR004347 Pup ligase/deamidase GO:0010498|GO:0019941 MetaCyc: PWY-7893 MB46_00890 ca2f27bd5e32398b4ea7d83183a01175 475 Pfam PF12821 Threonine/Serine exporter, ThrE 327 453 1.0E-9 T 14-10-2018 IPR024528 Threonine/Serine exporter, ThrE MB46_00890 ca2f27bd5e32398b4ea7d83183a01175 475 Pfam PF06738 Putative threonine/serine exporter 62 301 2.2E-51 T 14-10-2018 IPR010619 Putative threonine/serine exporter MB46_06380 bddf6cee3a3011e1cc5066641cce9207 329 Gene3D G3DSA:3.40.1090.10 25 102 1.5E-5 T 14-10-2018 MB46_06380 bddf6cee3a3011e1cc5066641cce9207 329 Gene3D G3DSA:3.40.1090.10 172 240 2.8E-6 T 14-10-2018 MB46_06380 bddf6cee3a3011e1cc5066641cce9207 329 SUPERFAMILY SSF52151 40 244 7.06E-21 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase MB46_14705 5781dcc288aab7478f8ab64b2fc3dc89 324 Gene3D G3DSA:3.40.50.300 20 251 8.6E-61 T 14-10-2018 MB46_14705 5781dcc288aab7478f8ab64b2fc3dc89 324 Pfam PF00005 ABC transporter 41 181 8.0E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_14705 5781dcc288aab7478f8ab64b2fc3dc89 324 SUPERFAMILY SSF52540 23 243 1.57E-57 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_14705 5781dcc288aab7478f8ab64b2fc3dc89 324 SMART SM00382 47 230 1.5E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_02580 98b4da48ed3ef76d379a1b55eddd1626 342 Pfam PF16363 GDP-mannose 4,6 dehydratase 6 316 6.0E-136 T 14-10-2018 IPR016040 NAD(P)-binding domain MB46_02580 98b4da48ed3ef76d379a1b55eddd1626 342 Hamap MF_00955 GDP-mannose 4,6-dehydratase [gmd]. 3 326 55.401 T 14-10-2018 IPR006368 GDP-mannose 4,6-dehydratase GO:0008446|GO:0019673 KEGG: 00051+4.2.1.47|KEGG: 00520+4.2.1.47|MetaCyc: PWY-5738|MetaCyc: PWY-5739|MetaCyc: PWY-5740|MetaCyc: PWY-66|MetaCyc: PWY-7573|Reactome: R-HSA-6787639 MB46_02580 98b4da48ed3ef76d379a1b55eddd1626 342 TIGRFAM TIGR01472 gmd: GDP-mannose 4,6-dehydratase 3 323 5.2E-153 T 14-10-2018 IPR006368 GDP-mannose 4,6-dehydratase GO:0008446|GO:0019673 KEGG: 00051+4.2.1.47|KEGG: 00520+4.2.1.47|MetaCyc: PWY-5738|MetaCyc: PWY-5739|MetaCyc: PWY-5740|MetaCyc: PWY-66|MetaCyc: PWY-7573|Reactome: R-HSA-6787639 MB46_02580 98b4da48ed3ef76d379a1b55eddd1626 342 Gene3D G3DSA:3.40.50.720 5 306 8.6E-142 T 14-10-2018 MB46_02580 98b4da48ed3ef76d379a1b55eddd1626 342 Gene3D G3DSA:3.90.25.10 190 318 8.6E-142 T 14-10-2018 MB46_02580 98b4da48ed3ef76d379a1b55eddd1626 342 SUPERFAMILY SSF51735 3 322 3.46E-75 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_18555 3d54f14796219fd6a4ab578b24ee7621 245 SUPERFAMILY SSF52172 19 197 1.05E-40 T 14-10-2018 IPR011006 CheY-like superfamily MB46_18555 3d54f14796219fd6a4ab578b24ee7621 245 SMART SM00448 21 132 1.2E-41 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MB46_18555 3d54f14796219fd6a4ab578b24ee7621 245 Gene3D G3DSA:1.10.10.10 145 244 4.4E-32 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_18555 3d54f14796219fd6a4ab578b24ee7621 245 Pfam PF00486 Transcriptional regulatory protein, C terminal 169 240 5.3E-25 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MB46_18555 3d54f14796219fd6a4ab578b24ee7621 245 Pfam PF00072 Response regulator receiver domain 24 131 3.7E-28 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MB46_18555 3d54f14796219fd6a4ab578b24ee7621 245 SMART SM00862 167 241 2.1E-25 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MB46_18555 3d54f14796219fd6a4ab578b24ee7621 245 Gene3D G3DSA:3.40.50.2300 11 143 2.2E-36 T 14-10-2018 MB46_14275 64bf1669c73eb13ac7c0f84f97d8761f 313 Pfam PF00005 ABC transporter 24 163 7.0E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_14275 64bf1669c73eb13ac7c0f84f97d8761f 313 Pfam PF13732 Domain of unknown function (DUF4162) 217 296 7.1E-11 T 14-10-2018 IPR025302 Domain of unknown function DUF4162 MB46_14275 64bf1669c73eb13ac7c0f84f97d8761f 313 SMART SM00382 32 211 4.9E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_14275 64bf1669c73eb13ac7c0f84f97d8761f 313 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_14275 64bf1669c73eb13ac7c0f84f97d8761f 313 Gene3D G3DSA:3.40.50.300 1 236 2.8E-64 T 14-10-2018 MB46_14275 64bf1669c73eb13ac7c0f84f97d8761f 313 SUPERFAMILY SSF52540 6 227 1.08E-59 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_04135 aac38da998c50fea2c8b81e6807897c6 348 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 5 134 8.5E-26 T 14-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 MB46_04135 aac38da998c50fea2c8b81e6807897c6 348 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 3 342 39.103 T 14-10-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 MB46_04135 aac38da998c50fea2c8b81e6807897c6 348 SMART SM00859 4 136 3.0E-43 T 14-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 MB46_04135 aac38da998c50fea2c8b81e6807897c6 348 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 141 157 - T 14-10-2018 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 MB46_04135 aac38da998c50fea2c8b81e6807897c6 348 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 164 319 6.6E-20 T 14-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 MB46_04135 aac38da998c50fea2c8b81e6807897c6 348 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 4 348 3.5E-113 T 14-10-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 MB46_04135 aac38da998c50fea2c8b81e6807897c6 348 Gene3D G3DSA:3.40.50.720 5 334 7.8E-117 T 14-10-2018 MB46_04135 aac38da998c50fea2c8b81e6807897c6 348 Gene3D G3DSA:3.30.360.10 150 321 7.8E-117 T 14-10-2018 MB46_04135 aac38da998c50fea2c8b81e6807897c6 348 SUPERFAMILY SSF55347 146 316 2.49E-46 T 14-10-2018 MB46_04135 aac38da998c50fea2c8b81e6807897c6 348 SUPERFAMILY SSF51735 3 174 3.48E-46 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_05455 00456e35150e6fa5c64f94fbbbd96ecf 977 Gene3D G3DSA:3.40.50.300 11 211 1.0E-61 T 14-10-2018 MB46_05455 00456e35150e6fa5c64f94fbbbd96ecf 977 Gene3D G3DSA:1.10.3380.30 769 970 4.2E-13 T 14-10-2018 MB46_05455 00456e35150e6fa5c64f94fbbbd96ecf 977 SMART SM01142 803 975 1.1E-58 T 14-10-2018 IPR012961 ATP-dependent RNA helicase Ski2, C-terminal MB46_05455 00456e35150e6fa5c64f94fbbbd96ecf 977 SMART SM00490 396 488 2.5E-11 T 14-10-2018 IPR001650 Helicase, C-terminal MB46_05455 00456e35150e6fa5c64f94fbbbd96ecf 977 Pfam PF13234 rRNA-processing arch domain 544 646 4.1E-5 T 14-10-2018 IPR025696 rRNA-processing arch domain MB46_05455 00456e35150e6fa5c64f94fbbbd96ecf 977 SUPERFAMILY SSF52540 48 502 2.05E-41 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_05455 00456e35150e6fa5c64f94fbbbd96ecf 977 SMART SM00487 34 216 2.3E-31 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MB46_05455 00456e35150e6fa5c64f94fbbbd96ecf 977 Pfam PF00270 DEAD/DEAH box helicase 40 187 3.6E-19 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MB46_05455 00456e35150e6fa5c64f94fbbbd96ecf 977 Pfam PF08148 DSHCT (NUC185) domain 807 970 6.2E-35 T 14-10-2018 IPR012961 ATP-dependent RNA helicase Ski2, C-terminal MB46_03810 7ce527272451fba5657a37abd9b26b00 746 Pfam PF00013 KH domain 590 647 7.3E-11 T 14-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 MB46_03810 7ce527272451fba5657a37abd9b26b00 746 SUPERFAMILY SSF54211 325 497 4.61E-44 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MB46_03810 7ce527272451fba5657a37abd9b26b00 746 SUPERFAMILY SSF55666 153 265 6.25E-24 T 14-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MB46_03810 7ce527272451fba5657a37abd9b26b00 746 Pfam PF01138 3' exoribonuclease family, domain 1 21 152 2.9E-14 T 14-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MB46_03810 7ce527272451fba5657a37abd9b26b00 746 Pfam PF01138 3' exoribonuclease family, domain 1 353 485 3.3E-16 T 14-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MB46_03810 7ce527272451fba5657a37abd9b26b00 746 TIGRFAM TIGR02696 pppGpp_PNP: guanosine pentaphosphate synthetase I/polyribonucleotide nucleotidyltransferase 5 726 0.0 T 14-10-2018 IPR014069 Guanosine pentaphosphate synthetase I/polyribonucleotide nucleotidyltransferase GO:0004654|GO:0005737|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 MB46_03810 7ce527272451fba5657a37abd9b26b00 746 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 274 348 6.2E-16 T 14-10-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 MB46_03810 7ce527272451fba5657a37abd9b26b00 746 SUPERFAMILY SSF54791 587 673 1.75E-18 T 14-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 MB46_03810 7ce527272451fba5657a37abd9b26b00 746 SUPERFAMILY SSF46915 270 350 2.59E-17 T 14-10-2018 IPR036456 Polyribonucleotide nucleotidyltransferase, RNA-binding domain superfamily GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 MB46_03810 7ce527272451fba5657a37abd9b26b00 746 SMART SM00316 654 728 1.2E-18 T 14-10-2018 IPR022967 RNA-binding domain, S1 MB46_03810 7ce527272451fba5657a37abd9b26b00 746 Gene3D G3DSA:3.30.230.70 266 582 4.1E-103 T 14-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MB46_03810 7ce527272451fba5657a37abd9b26b00 746 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 10 731 26.876 T 14-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 MB46_03810 7ce527272451fba5657a37abd9b26b00 746 SUPERFAMILY SSF50249 653 726 1.43E-14 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold MB46_03810 7ce527272451fba5657a37abd9b26b00 746 PIRSF PIRSF005499 8 746 8.6E-280 T 14-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 MB46_03810 7ce527272451fba5657a37abd9b26b00 746 SUPERFAMILY SSF54211 6 152 2.94E-44 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MB46_03810 7ce527272451fba5657a37abd9b26b00 746 SUPERFAMILY SSF55666 479 577 1.78E-22 T 14-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MB46_03810 7ce527272451fba5657a37abd9b26b00 746 Pfam PF00575 S1 RNA binding domain 653 726 1.0E-13 T 14-10-2018 IPR003029 S1 domain GO:0003676 MB46_03810 7ce527272451fba5657a37abd9b26b00 746 Gene3D G3DSA:3.30.230.70 5 255 2.2E-81 T 14-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MB46_03810 7ce527272451fba5657a37abd9b26b00 746 SMART SM00322 584 649 3.6E-11 T 14-10-2018 IPR004087 K Homology domain GO:0003676 MB46_03810 7ce527272451fba5657a37abd9b26b00 746 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 18 726 1.8E-257 T 14-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 MB46_03810 7ce527272451fba5657a37abd9b26b00 746 Gene3D G3DSA:2.40.50.140 583 710 1.3E-49 T 14-10-2018 MB46_13945 58d614fcb902340d0b499462f542df00 274 Pfam PF00005 ABC transporter 43 181 3.9E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_13945 58d614fcb902340d0b499462f542df00 274 SUPERFAMILY SSF52540 25 230 7.55E-63 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_13945 58d614fcb902340d0b499462f542df00 274 SMART SM00382 52 230 4.8E-18 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_13945 58d614fcb902340d0b499462f542df00 274 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_13945 58d614fcb902340d0b499462f542df00 274 Gene3D G3DSA:3.40.50.300 23 240 1.1E-61 T 14-10-2018 MB46_17410 14bec752ea19048e71129a04b0fd2a6f 141 Pfam PF00482 Type II secretion system (T2SS), protein F 8 128 8.8E-8 T 14-10-2018 IPR018076 Type II secretion system F domain MB46_06275 c28b3d9e3d87d981e74b2adf12d19780 372 SMART SM01002 149 297 1.5E-86 T 14-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain MB46_06275 c28b3d9e3d87d981e74b2adf12d19780 372 Gene3D G3DSA:3.40.50.720 3 353 6.6E-138 T 14-10-2018 MB46_06275 c28b3d9e3d87d981e74b2adf12d19780 372 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 141 352 2.9E-80 T 14-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain MB46_06275 c28b3d9e3d87d981e74b2adf12d19780 372 ProSitePatterns PS00837 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 2. 173 198 - T 14-10-2018 IPR008143 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 GO:0016491|GO:0055114 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1|Reactome: R-HSA-71403 MB46_06275 c28b3d9e3d87d981e74b2adf12d19780 372 SMART SM01003 4 137 6.6E-72 T 14-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal MB46_06275 c28b3d9e3d87d981e74b2adf12d19780 372 SUPERFAMILY SSF52283 1 360 6.63E-63 T 14-10-2018 MB46_06275 c28b3d9e3d87d981e74b2adf12d19780 372 Gene3D G3DSA:3.40.50.720 130 305 6.6E-138 T 14-10-2018 MB46_06275 c28b3d9e3d87d981e74b2adf12d19780 372 TIGRFAM TIGR00518 alaDH: alanine dehydrogenase 1 362 4.8E-169 T 14-10-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 MB46_06275 c28b3d9e3d87d981e74b2adf12d19780 372 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 5 137 2.6E-45 T 14-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal MB46_06275 c28b3d9e3d87d981e74b2adf12d19780 372 PIRSF PIRSF000183 1 371 1.9E-166 T 14-10-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 MB46_06275 c28b3d9e3d87d981e74b2adf12d19780 372 SUPERFAMILY SSF51735 137 303 3.38E-48 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_11905 5d3203b259aa008e31f221713fd5bbb7 405 Pfam PF02803 Thiolase, C-terminal domain 283 404 3.3E-46 T 14-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 MB46_11905 5d3203b259aa008e31f221713fd5bbb7 405 PIRSF PIRSF000429 2 405 1.9E-108 T 14-10-2018 IPR002155 Thiolase GO:0016747 MB46_11905 5d3203b259aa008e31f221713fd5bbb7 405 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 9 403 2.5E-132 T 14-10-2018 IPR002155 Thiolase GO:0016747 MB46_11905 5d3203b259aa008e31f221713fd5bbb7 405 Gene3D G3DSA:3.40.47.10 9 302 8.4E-146 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 MB46_11905 5d3203b259aa008e31f221713fd5bbb7 405 ProSitePatterns PS00737 Thiolases signature 2. 351 367 - T 14-10-2018 IPR020613 Thiolase, conserved site GO:0016747 MB46_11905 5d3203b259aa008e31f221713fd5bbb7 405 SUPERFAMILY SSF53901 283 404 4.68E-43 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 MB46_11905 5d3203b259aa008e31f221713fd5bbb7 405 Pfam PF00108 Thiolase, N-terminal domain 8 273 2.0E-45 T 14-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 MB46_11905 5d3203b259aa008e31f221713fd5bbb7 405 Gene3D G3DSA:3.40.47.10 128 400 8.4E-146 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 MB46_11905 5d3203b259aa008e31f221713fd5bbb7 405 ProSitePatterns PS00099 Thiolases active site. 386 399 - T 14-10-2018 IPR020610 Thiolase, active site GO:0016747 MB46_11905 5d3203b259aa008e31f221713fd5bbb7 405 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 90 108 - T 14-10-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0016747 MB46_11905 5d3203b259aa008e31f221713fd5bbb7 405 SUPERFAMILY SSF53901 5 276 7.95E-63 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 MB46_18740 e01e2ed777208ab8ae7f222b0129d300 278 Gene3D G3DSA:1.10.10.10 168 270 1.5E-27 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_18740 e01e2ed777208ab8ae7f222b0129d300 278 SUPERFAMILY SSF46894 174 263 3.83E-24 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MB46_18740 e01e2ed777208ab8ae7f222b0129d300 278 Pfam PF00486 Transcriptional regulatory protein, C terminal 189 262 6.8E-21 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MB46_18740 e01e2ed777208ab8ae7f222b0129d300 278 SMART SM00862 188 262 4.5E-22 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MB46_01070 d773a964c0ded6cef9b1b00b9c9e1c87 853 TIGRFAM TIGR01073 pcrA: ATP-dependent DNA helicase PcrA 80 849 1.0E-293 T 14-10-2018 IPR005751 ATP-dependent DNA helicase PcrA GO:0004003|GO:0005737|GO:0006268 MB46_01070 d773a964c0ded6cef9b1b00b9c9e1c87 853 Pfam PF00580 UvrD/REP helicase N-terminal domain 84 355 3.7E-78 T 14-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 MB46_01070 d773a964c0ded6cef9b1b00b9c9e1c87 853 Gene3D G3DSA:3.40.50.300 364 732 1.5E-126 T 14-10-2018 MB46_01070 d773a964c0ded6cef9b1b00b9c9e1c87 853 Pfam PF13361 UvrD-like helicase C-terminal domain 361 714 1.1E-66 T 14-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 MB46_01070 d773a964c0ded6cef9b1b00b9c9e1c87 853 SUPERFAMILY SSF52540 80 741 9.52E-178 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_01070 d773a964c0ded6cef9b1b00b9c9e1c87 853 Gene3D G3DSA:1.10.486.10 467 645 1.5E-126 T 14-10-2018 MB46_01070 d773a964c0ded6cef9b1b00b9c9e1c87 853 Gene3D G3DSA:3.40.50.300 84 358 2.9E-98 T 14-10-2018 MB46_01070 d773a964c0ded6cef9b1b00b9c9e1c87 853 Gene3D G3DSA:1.10.10.160 188 264 2.9E-98 T 14-10-2018 IPR013986 DExx box DNA helicase domain superfamily MB46_05830 8a07bee4b8a3b4f2b760472f2900d9ae 281 Hamap MF_01384 Urease accessory protein UreD [ureD]. 10 267 27.602 T 14-10-2018 IPR002669 Urease accessory protein UreD GO:0006807|GO:0016151 MB46_05830 8a07bee4b8a3b4f2b760472f2900d9ae 281 Pfam PF01774 UreD urease accessory protein 53 256 1.8E-49 T 14-10-2018 IPR002669 Urease accessory protein UreD GO:0006807|GO:0016151 MB46_14890 4e0a8882dcc6bce18bc301530f04c012 176 PIRSF PIRSF010260 1 175 4.4E-34 T 14-10-2018 IPR014457 Uncharacterised conserved protein UCP010260 MB46_14890 4e0a8882dcc6bce18bc301530f04c012 176 Pfam PF09348 Domain of unknown function (DUF1990) 12 167 1.5E-37 T 14-10-2018 IPR018960 Domain of unknown function DUF1990 MB46_02345 23971dd76316b462f25111b014cf8424 327 Pfam PF13400 Putative Flp pilus-assembly TadE/G-like 23 67 8.7E-14 T 14-10-2018 IPR028087 Putative Flp pilus-assembly TadG-like, N-terminal MB46_14590 9de0f2fa349d6dccbd79c42197762123 380 SUPERFAMILY SSF56801 39 375 3.4E-70 T 14-10-2018 MB46_14590 9de0f2fa349d6dccbd79c42197762123 380 Gene3D G3DSA:3.40.50.12780 22 276 2.1E-47 T 14-10-2018 MB46_14590 9de0f2fa349d6dccbd79c42197762123 380 ProSitePatterns PS00455 Putative AMP-binding domain signature. 50 61 - T 14-10-2018 IPR020845 AMP-binding, conserved site MB46_14590 9de0f2fa349d6dccbd79c42197762123 380 Gene3D G3DSA:3.30.300.30 278 372 6.2E-18 T 14-10-2018 MB46_14590 9de0f2fa349d6dccbd79c42197762123 380 Pfam PF00501 AMP-binding enzyme 42 283 1.8E-36 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 MB46_14590 9de0f2fa349d6dccbd79c42197762123 380 Pfam PF13193 AMP-binding enzyme C-terminal domain 297 363 3.7E-12 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain MB46_04900 7c788e29a221085b22f5c1981dd31891 574 Pfam PF13193 AMP-binding enzyme C-terminal domain 485 560 7.7E-13 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain MB46_04900 7c788e29a221085b22f5c1981dd31891 574 Gene3D G3DSA:3.40.50.12780 29 471 8.2E-113 T 14-10-2018 MB46_04900 7c788e29a221085b22f5c1981dd31891 574 SUPERFAMILY SSF56801 34 572 1.96E-147 T 14-10-2018 MB46_04900 7c788e29a221085b22f5c1981dd31891 574 ProSitePatterns PS00455 Putative AMP-binding domain signature. 226 237 - T 14-10-2018 IPR020845 AMP-binding, conserved site MB46_04900 7c788e29a221085b22f5c1981dd31891 574 Pfam PF00501 AMP-binding enzyme 44 476 8.3E-101 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 MB46_04900 7c788e29a221085b22f5c1981dd31891 574 Gene3D G3DSA:3.30.300.30 472 571 1.4E-25 T 14-10-2018 MB46_11785 30ffe3f874e982d9e9f784bb737a7791 263 SUPERFAMILY SSF52402 1 258 2.58E-60 T 14-10-2018 MB46_11785 30ffe3f874e982d9e9f784bb737a7791 263 Pfam PF01012 Electron transfer flavoprotein domain 29 211 2.6E-38 T 14-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 MB46_11785 30ffe3f874e982d9e9f784bb737a7791 263 PIRSF PIRSF000090 1 263 2.0E-68 T 14-10-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 MB46_11785 30ffe3f874e982d9e9f784bb737a7791 263 Gene3D G3DSA:3.40.50.620 1 263 1.4E-71 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MB46_11785 30ffe3f874e982d9e9f784bb737a7791 263 SMART SM00893 23 216 4.8E-43 T 14-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 MB46_02255 9ee6fea24ea5beca5b2f1e5ef4ead756 1142 SUPERFAMILY SSF53448 1 302 2.53E-32 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MB46_02255 9ee6fea24ea5beca5b2f1e5ef4ead756 1142 Pfam PF13641 Glycosyltransferase like family 2 83 252 3.1E-11 T 14-10-2018 MB46_01235 50f84b0dc96e8f3a0693355be526d4e1 297 Pfam PF08338 Domain of unknown function (DUF1731) 242 291 1.6E-12 T 14-10-2018 IPR013549 Domain of unknown function DUF1731 MB46_01235 50f84b0dc96e8f3a0693355be526d4e1 297 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 208 4.7E-15 T 14-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 MB46_01235 50f84b0dc96e8f3a0693355be526d4e1 297 SUPERFAMILY SSF51735 3 282 2.24E-34 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_01235 50f84b0dc96e8f3a0693355be526d4e1 297 TIGRFAM TIGR01777 yfcH: TIGR01777 family protein 4 288 2.8E-64 T 14-10-2018 IPR010099 Epimerase family protein SDR39U1 MB46_01235 50f84b0dc96e8f3a0693355be526d4e1 297 Gene3D G3DSA:3.40.50.720 2 282 2.4E-62 T 14-10-2018 MB46_01760 7afb7d0c99dd2f575f1b51409ea5e973 514 Pfam PF00005 ABC transporter 284 439 1.6E-19 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_01760 7afb7d0c99dd2f575f1b51409ea5e973 514 Gene3D G3DSA:3.40.50.300 265 514 4.4E-39 T 14-10-2018 MB46_01760 7afb7d0c99dd2f575f1b51409ea5e973 514 SMART SM00382 292 490 1.5E-6 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_01760 7afb7d0c99dd2f575f1b51409ea5e973 514 SMART SM00382 33 223 1.3E-6 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_01760 7afb7d0c99dd2f575f1b51409ea5e973 514 Gene3D G3DSA:3.40.50.300 4 237 9.2E-50 T 14-10-2018 MB46_01760 7afb7d0c99dd2f575f1b51409ea5e973 514 ProSitePatterns PS00211 ABC transporters family signature. 412 426 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_01760 7afb7d0c99dd2f575f1b51409ea5e973 514 SUPERFAMILY SSF52540 252 496 9.02E-43 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_01760 7afb7d0c99dd2f575f1b51409ea5e973 514 SUPERFAMILY SSF52540 7 229 9.43E-51 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_01760 7afb7d0c99dd2f575f1b51409ea5e973 514 Pfam PF00005 ABC transporter 24 175 1.4E-25 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_12740 eae49875bc09bd6ab038423971637da7 331 SUPERFAMILY SSF56327 160 327 2.16E-58 T 14-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 MB46_12740 eae49875bc09bd6ab038423971637da7 331 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 160 327 1.0E-30 T 14-10-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 MB46_12740 eae49875bc09bd6ab038423971637da7 331 Gene3D G3DSA:3.40.50.720 2 158 3.1E-50 T 14-10-2018 MB46_12740 eae49875bc09bd6ab038423971637da7 331 Gene3D G3DSA:3.90.110.10 159 329 3.1E-61 T 14-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 MB46_12740 eae49875bc09bd6ab038423971637da7 331 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 10 151 3.5E-29 T 14-10-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 MB46_12740 eae49875bc09bd6ab038423971637da7 331 PIRSF PIRSF000102 6 329 3.6E-58 T 14-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 MB46_12740 eae49875bc09bd6ab038423971637da7 331 Hamap MF_01517 Malate dehydrogenase [mdh]. 5 329 54.839 T 14-10-2018 IPR010945 Malate dehydrogenase, type 2 GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 MB46_12740 eae49875bc09bd6ab038423971637da7 331 TIGRFAM TIGR01759 MalateDH-SF1: malate dehydrogenase 7 325 5.8E-138 T 14-10-2018 IPR010945 Malate dehydrogenase, type 2 GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 MB46_12740 eae49875bc09bd6ab038423971637da7 331 SUPERFAMILY SSF51735 8 159 2.31E-39 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_12740 eae49875bc09bd6ab038423971637da7 331 ProSitePatterns PS00068 Malate dehydrogenase active site signature. 159 171 - T 14-10-2018 IPR001252 Malate dehydrogenase, active site GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383|Reactome: R-HSA-70263 MB46_05285 120e24dc1732bbe14ef875c6f8f14d63 400 Pfam PF13439 Glycosyltransferase Family 4 15 182 4.6E-28 T 14-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 MB46_05285 120e24dc1732bbe14ef875c6f8f14d63 400 Pfam PF00534 Glycosyl transferases group 1 191 375 2.6E-28 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 MB46_05285 120e24dc1732bbe14ef875c6f8f14d63 400 Gene3D G3DSA:3.40.50.2000 179 376 4.1E-78 T 14-10-2018 MB46_05285 120e24dc1732bbe14ef875c6f8f14d63 400 SUPERFAMILY SSF53756 9 397 8.85E-83 T 14-10-2018 MB46_05285 120e24dc1732bbe14ef875c6f8f14d63 400 TIGRFAM TIGR02149 glgA_Coryne: glycogen synthase, Corynebacterium family 2 397 1.0E-170 T 14-10-2018 IPR011875 Alpha-maltose-1-phosphate synthase GO:0009250|GO:0016740 KEGG: 00500+2.4.1.342|MetaCyc: PWY-7900 MB46_05285 120e24dc1732bbe14ef875c6f8f14d63 400 Gene3D G3DSA:3.40.50.2000 6 393 4.1E-78 T 14-10-2018 MB46_17770 a45ea16b432c1e9f610340f06f60900d 220 SUPERFAMILY SSF53254 5 204 6.24E-33 T 14-10-2018 IPR029033 Histidine phosphatase superfamily MB46_17770 a45ea16b432c1e9f610340f06f60900d 220 Gene3D G3DSA:3.40.50.1240 1 207 4.2E-25 T 14-10-2018 IPR029033 Histidine phosphatase superfamily MB46_17770 a45ea16b432c1e9f610340f06f60900d 220 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 6 199 4.1E-27 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MB46_17770 a45ea16b432c1e9f610340f06f60900d 220 SMART SM00855 5 165 1.9E-14 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MB46_16815 c12708b49484df43b20648a105a24b3c 452 SUPERFAMILY SSF103473 15 448 1.44E-48 T 14-10-2018 IPR036259 MFS transporter superfamily MB46_16815 c12708b49484df43b20648a105a24b3c 452 Pfam PF07690 Major Facilitator Superfamily 20 406 5.9E-39 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MB46_08920 019db9889c68c31e745d1daacd7f2ba3 255 PIRSF PIRSF000709 15 196 8.0E-12 T 14-10-2018 MB46_08920 019db9889c68c31e745d1daacd7f2ba3 255 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 20 209 2.0E-47 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MB46_08920 019db9889c68c31e745d1daacd7f2ba3 255 Gene3D G3DSA:3.40.50.1240 17 236 5.7E-55 T 14-10-2018 IPR029033 Histidine phosphatase superfamily MB46_08920 019db9889c68c31e745d1daacd7f2ba3 255 SUPERFAMILY SSF53254 18 208 3.43E-48 T 14-10-2018 IPR029033 Histidine phosphatase superfamily MB46_08920 019db9889c68c31e745d1daacd7f2ba3 255 SMART SM00855 19 180 2.7E-17 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MB46_05145 d9c63b39c9d8156a25c8c4e9b07a1fe2 118 Pfam PF00355 Rieske [2Fe-2S] domain 10 95 4.2E-18 T 14-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MB46_05145 d9c63b39c9d8156a25c8c4e9b07a1fe2 118 SUPERFAMILY SSF50022 8 109 2.23E-27 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 MB46_05145 d9c63b39c9d8156a25c8c4e9b07a1fe2 118 Gene3D G3DSA:2.102.10.10 2 113 3.2E-31 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 MB46_14660 5e19074a1dcfbcee2b7c5252a315c2bc 295 Gene3D G3DSA:3.40.50.1000 10 238 7.2E-6 T 14-10-2018 IPR023214 HAD superfamily MB46_14660 5e19074a1dcfbcee2b7c5252a315c2bc 295 SUPERFAMILY SSF56784 9 279 3.08E-9 T 14-10-2018 IPR036412 HAD-like superfamily MB46_14660 5e19074a1dcfbcee2b7c5252a315c2bc 295 Gene3D G3DSA:3.30.1240.10 102 198 7.2E-6 T 14-10-2018 MB46_12875 d7570b0f0ec88cf87980c42bc0b31820 156 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 11 131 1.1E-40 T 14-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 MB46_12875 d7570b0f0ec88cf87980c42bc0b31820 156 Gene3D G3DSA:2.70.70.10 2 154 5.3E-50 T 14-10-2018 IPR011055 Duplicated hybrid motif MB46_12875 d7570b0f0ec88cf87980c42bc0b31820 156 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 10 134 1.9E-45 T 14-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 MB46_12875 d7570b0f0ec88cf87980c42bc0b31820 156 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 73 85 - T 14-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 MB46_12875 d7570b0f0ec88cf87980c42bc0b31820 156 SUPERFAMILY SSF51261 3 143 2.27E-46 T 14-10-2018 IPR011055 Duplicated hybrid motif MB46_00955 af8b3c7cb456daf9dd60e291dc64472d 545 Pfam PF04851 Type III restriction enzyme, res subunit 183 328 8.6E-12 T 14-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 MB46_00955 af8b3c7cb456daf9dd60e291dc64472d 545 SMART SM00487 180 355 2.8E-21 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MB46_00955 af8b3c7cb456daf9dd60e291dc64472d 545 Gene3D G3DSA:3.40.50.300 356 545 3.2E-49 T 14-10-2018 MB46_00955 af8b3c7cb456daf9dd60e291dc64472d 545 SUPERFAMILY SSF52540 178 347 2.75E-31 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_00955 af8b3c7cb456daf9dd60e291dc64472d 545 Pfam PF16203 ERCC3/RAD25/XPB C-terminal helicase 355 541 1.3E-47 T 14-10-2018 IPR032438 ERCC3/RAD25/XPB helicase, C-terminal domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 MB46_00955 af8b3c7cb456daf9dd60e291dc64472d 545 Gene3D G3DSA:3.40.50.300 172 355 2.7E-35 T 14-10-2018 MB46_00955 af8b3c7cb456daf9dd60e291dc64472d 545 SMART SM00490 425 502 1.1E-12 T 14-10-2018 IPR001650 Helicase, C-terminal MB46_00955 af8b3c7cb456daf9dd60e291dc64472d 545 SUPERFAMILY SSF52540 292 513 1.32E-28 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_00955 af8b3c7cb456daf9dd60e291dc64472d 545 Pfam PF13625 Helicase conserved C-terminal domain 6 134 1.2E-42 T 14-10-2018 IPR032830 Helicase XPB/Ssl2, N-terminal domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 MB46_00955 af8b3c7cb456daf9dd60e291dc64472d 545 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 412 434 2.1E-28 T 14-10-2018 MB46_00955 af8b3c7cb456daf9dd60e291dc64472d 545 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 458 476 2.1E-28 T 14-10-2018 MB46_00955 af8b3c7cb456daf9dd60e291dc64472d 545 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 358 380 2.1E-28 T 14-10-2018 MB46_00955 af8b3c7cb456daf9dd60e291dc64472d 545 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 293 313 2.1E-28 T 14-10-2018 MB46_00955 af8b3c7cb456daf9dd60e291dc64472d 545 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 165 191 2.1E-28 T 14-10-2018 MB46_00955 af8b3c7cb456daf9dd60e291dc64472d 545 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 477 502 2.1E-28 T 14-10-2018 MB46_14915 e590cb6c4a689110792b6a5fe1a363ff 170 Pfam PF14435 SUKH-4 immunity protein 29 128 3.9E-7 T 14-10-2018 IPR025851 SUKH-4 immunity protein MB46_14440 9c4dc42bd9985a25587edc558741f214 340 Gene3D G3DSA:1.20.1260.10 31 340 6.5E-126 T 14-10-2018 IPR012347 Ferritin-like MB46_14440 9c4dc42bd9985a25587edc558741f214 340 Pfam PF05138 Phenylacetic acid catabolic protein 48 322 1.7E-95 T 14-10-2018 IPR007814 1,2-phenylacetyl-CoA epoxidase, subunit A/C GO:0010124 MB46_14440 9c4dc42bd9985a25587edc558741f214 340 TIGRFAM TIGR02156 PA_CoA_Oxy1: phenylacetate-CoA oxygenase, PaaG subunit 38 326 2.8E-146 T 14-10-2018 IPR011881 1,2-phenylacetyl-CoA epoxidase, subunit A GO:0010124|GO:0097266 KEGG: 00360+1.14.13.149 MB46_14440 9c4dc42bd9985a25587edc558741f214 340 SUPERFAMILY SSF47240 58 299 3.45E-75 T 14-10-2018 IPR009078 Ferritin-like superfamily MB46_18260 870686d916ab2001dad5fa2f60d7760a 316 SUPERFAMILY SSF82171 7 298 6.67E-39 T 14-10-2018 MB46_18260 870686d916ab2001dad5fa2f60d7760a 316 Pfam PF07676 WD40-like Beta Propeller Repeat 35 53 0.038 T 14-10-2018 IPR011659 WD40-like Beta Propeller MB46_18260 870686d916ab2001dad5fa2f60d7760a 316 Pfam PF07676 WD40-like Beta Propeller Repeat 276 290 0.074 T 14-10-2018 IPR011659 WD40-like Beta Propeller MB46_18260 870686d916ab2001dad5fa2f60d7760a 316 Pfam PF07676 WD40-like Beta Propeller Repeat 163 195 3.2E-6 T 14-10-2018 IPR011659 WD40-like Beta Propeller MB46_18260 870686d916ab2001dad5fa2f60d7760a 316 Pfam PF07676 WD40-like Beta Propeller Repeat 225 239 0.022 T 14-10-2018 IPR011659 WD40-like Beta Propeller MB46_18260 870686d916ab2001dad5fa2f60d7760a 316 Gene3D G3DSA:2.120.10.30 8 293 7.8E-79 T 14-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like MB46_03070 1bd0ef85ebaf9371701e13f66114694b 312 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 305 2.1E-16 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_03070 1bd0ef85ebaf9371701e13f66114694b 312 Gene3D G3DSA:1.10.3720.10 27 303 4.8E-61 T 14-10-2018 IPR035906 MetI-like superfamily MB46_03070 1bd0ef85ebaf9371701e13f66114694b 312 SUPERFAMILY SSF161098 34 312 6.41E-53 T 14-10-2018 IPR035906 MetI-like superfamily MB46_19580 21d4aeeaf2663c58407592e5b7938745 604 SUPERFAMILY SSF52540 153 572 7.96E-33 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_19580 21d4aeeaf2663c58407592e5b7938745 604 Gene3D G3DSA:3.40.50.300 360 575 2.5E-32 T 14-10-2018 MB46_19580 21d4aeeaf2663c58407592e5b7938745 604 Pfam PF12696 TraM recognition site of TraD and TraG 428 544 8.0E-25 T 14-10-2018 IPR032689 TraD/TraG, TraM recognition site MB46_12490 0038d6a3573e417eed2a32c046be61a1 208 SUPERFAMILY SSF48498 96 206 1.22E-14 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily MB46_12490 0038d6a3573e417eed2a32c046be61a1 208 ProSitePatterns PS01081 TetR-type HTH domain signature. 26 57 - T 14-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site MB46_12490 0038d6a3573e417eed2a32c046be61a1 208 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 98 206 7.3E-15 T 14-10-2018 IPR039538 BetI-type transcriptional repressor, C-terminal MB46_12490 0038d6a3573e417eed2a32c046be61a1 208 Gene3D G3DSA:1.10.357.10 5 208 1.8E-40 T 14-10-2018 MB46_12490 0038d6a3573e417eed2a32c046be61a1 208 SUPERFAMILY SSF46689 6 70 2.26E-11 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MB46_12490 0038d6a3573e417eed2a32c046be61a1 208 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 58 4.0E-5 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MB46_11505 631ffa0c6556fc441b466590142dda65 389 Pfam PF13692 Glycosyl transferases group 1 206 349 1.2E-11 T 14-10-2018 MB46_11505 631ffa0c6556fc441b466590142dda65 389 Gene3D G3DSA:3.40.50.2000 204 361 7.0E-18 T 14-10-2018 MB46_11505 631ffa0c6556fc441b466590142dda65 389 Pfam PF13579 Glycosyl transferase 4-like domain 23 188 5.7E-14 T 14-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 MB46_11505 631ffa0c6556fc441b466590142dda65 389 SUPERFAMILY SSF53756 8 356 1.47E-36 T 14-10-2018 MB46_11505 631ffa0c6556fc441b466590142dda65 389 Gene3D G3DSA:3.40.50.2000 4 203 1.8E-17 T 14-10-2018 MB46_04725 1af367cdbef7cee44f891d9d33494b79 95 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 1 75 9.7E-18 T 14-10-2018 IPR000032 Phosphocarrier protein HPr-like MB46_04725 1af367cdbef7cee44f891d9d33494b79 95 Pfam PF00381 PTS HPr component phosphorylation site 3 88 2.4E-19 T 14-10-2018 IPR000032 Phosphocarrier protein HPr-like MB46_04725 1af367cdbef7cee44f891d9d33494b79 95 Gene3D G3DSA:3.30.1340.10 1 91 1.6E-17 T 14-10-2018 IPR035895 HPr-like superfamily MB46_04725 1af367cdbef7cee44f891d9d33494b79 95 SUPERFAMILY SSF55594 1 91 2.75E-16 T 14-10-2018 IPR035895 HPr-like superfamily MB46_04725 1af367cdbef7cee44f891d9d33494b79 95 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 13 20 - T 14-10-2018 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site MB46_04725 1af367cdbef7cee44f891d9d33494b79 95 PRINTS PR00107 Phosphocarrier protein signature 39 54 3.1E-6 T 14-10-2018 IPR000032 Phosphocarrier protein HPr-like MB46_04725 1af367cdbef7cee44f891d9d33494b79 95 PRINTS PR00107 Phosphocarrier protein signature 13 29 3.1E-6 T 14-10-2018 IPR000032 Phosphocarrier protein HPr-like MB46_04725 1af367cdbef7cee44f891d9d33494b79 95 PRINTS PR00107 Phosphocarrier protein signature 54 71 3.1E-6 T 14-10-2018 IPR000032 Phosphocarrier protein HPr-like MB46_10825 48e225f0d629b51ee8ae34007fbd3d4f 445 SUPERFAMILY SSF53474 188 440 1.33E-28 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_10825 48e225f0d629b51ee8ae34007fbd3d4f 445 Pfam PF00756 Putative esterase 203 437 1.1E-16 T 14-10-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 MB46_10825 48e225f0d629b51ee8ae34007fbd3d4f 445 Gene3D G3DSA:3.40.50.1820 169 441 1.7E-39 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_08040 78249571a9c4bfbfcdaebb14959d05e9 313 Pfam PF09754 PAC2 family 37 253 2.4E-38 T 14-10-2018 IPR019151 Proteasome assembly chaperone 2 MB46_08040 78249571a9c4bfbfcdaebb14959d05e9 313 Gene3D G3DSA:3.40.50.10900 10 233 8.2E-69 T 14-10-2018 IPR038389 Proteasome assembly chaperone 2 superfamily MB46_08040 78249571a9c4bfbfcdaebb14959d05e9 313 SUPERFAMILY SSF159659 22 275 2.35E-78 T 14-10-2018 MB46_08040 78249571a9c4bfbfcdaebb14959d05e9 313 Gene3D G3DSA:1.10.287.100 235 276 8.5E-13 T 14-10-2018 MB46_08040 78249571a9c4bfbfcdaebb14959d05e9 313 PIRSF PIRSF028754 14 312 1.0E-85 T 14-10-2018 IPR008492 Protein of unknown function DUF774 MB46_07830 a81e425bb18afe4610a88298548bf57a 356 SUPERFAMILY SSF53383 18 353 9.33E-92 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MB46_07830 a81e425bb18afe4610a88298548bf57a 356 Gene3D G3DSA:3.90.1150.10 22 347 5.0E-128 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MB46_07830 a81e425bb18afe4610a88298548bf57a 356 Gene3D G3DSA:3.40.640.10 29 266 5.0E-128 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MB46_07830 a81e425bb18afe4610a88298548bf57a 356 Pfam PF01212 Beta-eliminating lyase 20 302 1.8E-56 T 14-10-2018 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 MB46_04995 e32b28dc6fb2c49017ee68f82d515402 276 Gene3D G3DSA:1.10.150.290 152 257 8.0E-80 T 14-10-2018 IPR023149 Trans-aconitate 2-methyltransferase, C-terminal GO:0030798 MB46_04995 e32b28dc6fb2c49017ee68f82d515402 276 Pfam PF13649 Methyltransferase domain 39 143 2.8E-14 T 14-10-2018 MB46_04995 e32b28dc6fb2c49017ee68f82d515402 276 SUPERFAMILY SSF53335 27 260 2.76E-28 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MB46_04995 e32b28dc6fb2c49017ee68f82d515402 276 Gene3D G3DSA:3.40.50.150 13 272 8.0E-80 T 14-10-2018 MB46_16150 60bd4509a50701203ddb3e47d8eff2f9 292 Pfam PF00892 EamA-like transporter family 144 278 4.6E-12 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MB46_16150 60bd4509a50701203ddb3e47d8eff2f9 292 Pfam PF00892 EamA-like transporter family 4 132 7.7E-7 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MB46_16150 60bd4509a50701203ddb3e47d8eff2f9 292 SUPERFAMILY SSF103481 33 134 1.96E-7 T 14-10-2018 MB46_16150 60bd4509a50701203ddb3e47d8eff2f9 292 SUPERFAMILY SSF103481 183 282 1.27E-11 T 14-10-2018 MB46_09475 f04e01d7fa8fb497aa1ff12be59c0ea9 317 SUPERFAMILY SSF55048 132 184 8.76E-12 T 14-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding MB46_09475 f04e01d7fa8fb497aa1ff12be59c0ea9 317 Gene3D G3DSA:3.40.366.10 3 283 4.3E-79 T 14-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 MB46_09475 f04e01d7fa8fb497aa1ff12be59c0ea9 317 SUPERFAMILY SSF52151 2 309 1.12E-63 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase MB46_09475 f04e01d7fa8fb497aa1ff12be59c0ea9 317 Pfam PF00698 Acyl transferase domain 5 285 1.9E-15 T 14-10-2018 IPR014043 Acyl transferase MB46_09475 f04e01d7fa8fb497aa1ff12be59c0ea9 317 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 5 316 1.7E-16 T 14-10-2018 IPR020801 Polyketide synthase, acyl transferase domain MB46_09475 f04e01d7fa8fb497aa1ff12be59c0ea9 317 Gene3D G3DSA:3.30.70.250 130 193 4.3E-79 T 14-10-2018 MB46_18285 2747e4f1070ea534cc6763c117508618 486 Gene3D G3DSA:1.10.260.40 17 96 2.4E-17 T 14-10-2018 MB46_18285 2747e4f1070ea534cc6763c117508618 486 Pfam PF01381 Helix-turn-helix 23 75 8.0E-12 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MB46_18285 2747e4f1070ea534cc6763c117508618 486 SUPERFAMILY SSF47413 15 82 4.83E-16 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MB46_18285 2747e4f1070ea534cc6763c117508618 486 SMART SM00530 21 76 1.9E-15 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MB46_18285 2747e4f1070ea534cc6763c117508618 486 Pfam PF06114 IrrE N-terminal-like domain 211 310 1.0E-7 T 14-10-2018 IPR010359 IrrE N-terminal-like domain MB46_14055 dd29ab045a4ca4afe39511d6f3da129c 390 Gene3D G3DSA:3.40.640.10 47 298 3.0E-55 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MB46_14055 dd29ab045a4ca4afe39511d6f3da129c 390 SUPERFAMILY SSF53383 33 386 1.17E-48 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MB46_14055 dd29ab045a4ca4afe39511d6f3da129c 390 Pfam PF00266 Aminotransferase class-V 77 365 1.4E-20 T 14-10-2018 IPR000192 Aminotransferase class V domain MB46_14055 dd29ab045a4ca4afe39511d6f3da129c 390 Gene3D G3DSA:3.90.1150.10 34 379 3.0E-55 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MB46_08250 2dc535d627c0287b5d306b61bcfa76b4 517 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 143 166 - T 14-10-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 MB46_08250 2dc535d627c0287b5d306b61bcfa76b4 517 SUPERFAMILY SSF51984 22 123 9.94E-13 T 14-10-2018 MB46_08250 2dc535d627c0287b5d306b61bcfa76b4 517 Gene3D G3DSA:3.90.190.20 352 502 6.9E-36 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MB46_08250 2dc535d627c0287b5d306b61bcfa76b4 517 SUPERFAMILY SSF53623 139 348 3.14E-45 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 MB46_08250 2dc535d627c0287b5d306b61bcfa76b4 517 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 27 504 1.6E-116 T 14-10-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MB46_08250 2dc535d627c0287b5d306b61bcfa76b4 517 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 26 506 31.546 T 14-10-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MB46_08250 2dc535d627c0287b5d306b61bcfa76b4 517 Pfam PF08245 Mur ligase middle domain 145 330 4.5E-23 T 14-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 MB46_08250 2dc535d627c0287b5d306b61bcfa76b4 517 SUPERFAMILY SSF53244 352 506 4.44E-36 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MB46_08250 2dc535d627c0287b5d306b61bcfa76b4 517 Pfam PF02875 Mur ligase family, glutamate ligase domain 353 422 3.0E-10 T 14-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 MB46_08250 2dc535d627c0287b5d306b61bcfa76b4 517 Gene3D G3DSA:3.40.1190.10 123 350 8.5E-49 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 MB46_08250 2dc535d627c0287b5d306b61bcfa76b4 517 Gene3D G3DSA:3.40.50.720 21 121 4.6E-14 T 14-10-2018 MB46_13465 886f144584b135bda54172a7563a505b 156 Gene3D G3DSA:1.10.455.10 2 156 5.9E-58 T 14-10-2018 IPR036823 Ribosomal protein S7 domain superfamily MB46_13465 886f144584b135bda54172a7563a505b 156 PIRSF PIRSF002122 6 156 3.0E-55 T 14-10-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 MB46_13465 886f144584b135bda54172a7563a505b 156 Pfam PF00177 Ribosomal protein S7p/S5e 1 149 1.4E-60 T 14-10-2018 IPR023798 Ribosomal protein S7 domain MB46_13465 886f144584b135bda54172a7563a505b 156 SUPERFAMILY SSF47973 1 149 1.83E-57 T 14-10-2018 IPR036823 Ribosomal protein S7 domain superfamily MB46_13465 886f144584b135bda54172a7563a505b 156 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 14-10-2018 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MB46_13465 886f144584b135bda54172a7563a505b 156 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 156 34.613 T 14-10-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 MB46_13465 886f144584b135bda54172a7563a505b 156 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 156 2.5E-65 T 14-10-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 MB46_07685 0f5b6cea89a3b3296fd8e429ce9ce7c4 162 Gene3D G3DSA:3.40.50.960 7 161 9.3E-57 T 14-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MB46_07685 0f5b6cea89a3b3296fd8e429ce9ce7c4 162 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 22 154 3.9E-51 T 14-10-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MB46_07685 0f5b6cea89a3b3296fd8e429ce9ce7c4 162 SUPERFAMILY SSF52121 15 160 2.09E-52 T 14-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MB46_07685 0f5b6cea89a3b3296fd8e429ce9ce7c4 162 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 17 160 27.75 T 14-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MB46_07685 0f5b6cea89a3b3296fd8e429ce9ce7c4 162 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 22 155 1.6E-40 T 14-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MB46_01150 09eb436b64822d81f36d02daf3e0024d 195 Gene3D G3DSA:2.60.120.10 97 193 8.5E-15 T 14-10-2018 IPR014710 RmlC-like jelly roll fold MB46_01150 09eb436b64822d81f36d02daf3e0024d 195 Pfam PF07883 Cupin domain 136 184 8.2E-11 T 14-10-2018 IPR013096 Cupin 2, conserved barrel MB46_01150 09eb436b64822d81f36d02daf3e0024d 195 SUPERFAMILY SSF51182 58 188 1.64E-18 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily MB46_01150 09eb436b64822d81f36d02daf3e0024d 195 SMART SM00530 18 73 3.7E-11 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MB46_01150 09eb436b64822d81f36d02daf3e0024d 195 SUPERFAMILY SSF47413 13 79 4.22E-15 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MB46_01150 09eb436b64822d81f36d02daf3e0024d 195 Pfam PF01381 Helix-turn-helix 19 73 7.3E-10 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MB46_01150 09eb436b64822d81f36d02daf3e0024d 195 Gene3D G3DSA:1.10.260.40 13 86 1.8E-15 T 14-10-2018 MB46_08220 3c5bca37211ac18dd39c91eb300700de 265 Pfam PF02578 Multi-copper polyphenol oxidoreductase laccase 20 247 9.9E-50 T 14-10-2018 IPR003730 Multi-copper polyphenol oxidoreductase MB46_08220 3c5bca37211ac18dd39c91eb300700de 265 Gene3D G3DSA:3.60.140.10 4 250 1.2E-53 T 14-10-2018 IPR038371 Multi-copper polyphenol oxidoreductase superfamily MB46_08220 3c5bca37211ac18dd39c91eb300700de 265 SUPERFAMILY SSF64438 7 248 1.28E-42 T 14-10-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic MB46_09295 926ba79e064c20efb53407bc947325da 167 Pfam PF00582 Universal stress protein family 11 157 2.0E-13 T 14-10-2018 IPR006016 UspA MB46_09295 926ba79e064c20efb53407bc947325da 167 Gene3D G3DSA:3.40.50.620 16 159 3.1E-14 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MB46_09295 926ba79e064c20efb53407bc947325da 167 SUPERFAMILY SSF52402 18 157 4.86E-14 T 14-10-2018 MB46_13635 5c73b81e2f5287b22d68a383a8466dca 305 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 117 299 9.9E-15 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_13635 5c73b81e2f5287b22d68a383a8466dca 305 Gene3D G3DSA:1.10.3720.10 29 297 3.0E-68 T 14-10-2018 IPR035906 MetI-like superfamily MB46_13635 5c73b81e2f5287b22d68a383a8466dca 305 SUPERFAMILY SSF161098 35 305 1.78E-71 T 14-10-2018 IPR035906 MetI-like superfamily MB46_10960 4085c28824b52cb5006962e33b4bbad1 423 Pfam PF07690 Major Facilitator Superfamily 25 366 2.0E-19 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MB46_10960 4085c28824b52cb5006962e33b4bbad1 423 Gene3D G3DSA:1.20.1250.20 225 413 4.6E-18 T 14-10-2018 MB46_10960 4085c28824b52cb5006962e33b4bbad1 423 Gene3D G3DSA:1.20.1250.20 2 194 1.6E-10 T 14-10-2018 MB46_10960 4085c28824b52cb5006962e33b4bbad1 423 SUPERFAMILY SSF103473 5 410 2.35E-40 T 14-10-2018 IPR036259 MFS transporter superfamily MB46_19100 d7a84fa762da72614f0d263a1cffa116 668 Hamap MF_02124 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase [glgE]. 2 668 43.156 T 14-10-2018 IPR026585 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase GO:0016757 KEGG: 00500+2.4.99.16|MetaCyc: PWY-7900 MB46_19100 d7a84fa762da72614f0d263a1cffa116 668 Pfam PF11896 Domain of unknown function (DUF3416) 4 193 1.4E-50 T 14-10-2018 IPR021828 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase, domain N/S GO:0004553 KEGG: 00500+2.4.99.16|MetaCyc: PWY-7900 MB46_19100 d7a84fa762da72614f0d263a1cffa116 668 SMART SM00642 199 536 3.3E-4 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MB46_19100 d7a84fa762da72614f0d263a1cffa116 668 Gene3D G3DSA:3.20.20.80 194 566 1.5E-157 T 14-10-2018 MB46_19100 d7a84fa762da72614f0d263a1cffa116 668 Gene3D G3DSA:2.60.40.10 5 193 1.9E-54 T 14-10-2018 IPR013783 Immunoglobulin-like fold MB46_19100 d7a84fa762da72614f0d263a1cffa116 668 Gene3D G3DSA:2.60.40.1180 567 668 3.6E-25 T 14-10-2018 IPR013780 Glycosyl hydrolase, all-beta MB46_19100 d7a84fa762da72614f0d263a1cffa116 668 SUPERFAMILY SSF51445 188 561 1.01E-80 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily MB46_19100 d7a84fa762da72614f0d263a1cffa116 668 Gene3D G3DSA:1.20.58.280 94 174 1.9E-54 T 14-10-2018 MB46_14615 3f46c192ed75aadb2ae4295ebefdfb3b 202 SUPERFAMILY SSF46689 13 66 6.48E-8 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MB46_14615 3f46c192ed75aadb2ae4295ebefdfb3b 202 Gene3D G3DSA:1.10.357.10 5 190 2.8E-13 T 14-10-2018 MB46_14615 3f46c192ed75aadb2ae4295ebefdfb3b 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 65 2.2E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MB46_10660 0285819dc4ae93ba2a281a50ee2eb531 312 PRINTS PR00783 Major intrinsic protein family signature 18 37 1.7E-32 T 14-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 MB46_10660 0285819dc4ae93ba2a281a50ee2eb531 312 PRINTS PR00783 Major intrinsic protein family signature 90 109 1.7E-32 T 14-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 MB46_10660 0285819dc4ae93ba2a281a50ee2eb531 312 PRINTS PR00783 Major intrinsic protein family signature 220 240 1.7E-32 T 14-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 MB46_10660 0285819dc4ae93ba2a281a50ee2eb531 312 PRINTS PR00783 Major intrinsic protein family signature 53 77 1.7E-32 T 14-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 MB46_10660 0285819dc4ae93ba2a281a50ee2eb531 312 PRINTS PR00783 Major intrinsic protein family signature 151 169 1.7E-32 T 14-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 MB46_10660 0285819dc4ae93ba2a281a50ee2eb531 312 PRINTS PR00783 Major intrinsic protein family signature 181 203 1.7E-32 T 14-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 MB46_10660 0285819dc4ae93ba2a281a50ee2eb531 312 SUPERFAMILY SSF81338 19 241 1.31E-42 T 14-10-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 MB46_10660 0285819dc4ae93ba2a281a50ee2eb531 312 Gene3D G3DSA:1.20.1080.10 11 243 9.0E-50 T 14-10-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 MB46_10660 0285819dc4ae93ba2a281a50ee2eb531 312 Pfam PF00230 Major intrinsic protein 20 237 2.2E-28 T 14-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 MB46_00305 9cf0ba451447713e5e2d59c9854c19ff 337 SUPERFAMILY SSF51735 3 154 2.36E-37 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_00305 9cf0ba451447713e5e2d59c9854c19ff 337 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 5 125 1.7E-22 T 14-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 MB46_00305 9cf0ba451447713e5e2d59c9854c19ff 337 Gene3D G3DSA:3.40.50.720 6 315 5.9E-91 T 14-10-2018 MB46_00305 9cf0ba451447713e5e2d59c9854c19ff 337 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 141 238 3.0E-5 T 14-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 MB46_00305 9cf0ba451447713e5e2d59c9854c19ff 337 SUPERFAMILY SSF55347 137 298 1.28E-12 T 14-10-2018 MB46_00305 9cf0ba451447713e5e2d59c9854c19ff 337 Hamap MF_01671 Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase [iolG]. 3 337 46.137 T 14-10-2018 IPR023794 Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase GO:0019310|GO:0050112|GO:0055114 KEGG: 00521+1.1.1.18|KEGG: 00562+1.1.1.18|MetaCyc: PWY-5940|MetaCyc: PWY-7237|MetaCyc: PWY-7241 MB46_00305 9cf0ba451447713e5e2d59c9854c19ff 337 Gene3D G3DSA:3.30.360.10 145 267 5.9E-91 T 14-10-2018 MB46_14170 6d15ccc2fb7d3dc006d95a96f470f6c8 395 Pfam PF07690 Major Facilitator Superfamily 29 353 2.7E-13 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MB46_14170 6d15ccc2fb7d3dc006d95a96f470f6c8 395 Gene3D G3DSA:1.20.1250.20 10 194 6.5E-11 T 14-10-2018 MB46_14170 6d15ccc2fb7d3dc006d95a96f470f6c8 395 Gene3D G3DSA:1.20.1250.20 207 394 9.6E-12 T 14-10-2018 MB46_14170 6d15ccc2fb7d3dc006d95a96f470f6c8 395 SUPERFAMILY SSF103473 5 387 4.71E-30 T 14-10-2018 IPR036259 MFS transporter superfamily MB46_06790 57a5f3705598806e2f5d414c507a86a1 547 SUPERFAMILY SSF55874 422 540 1.7E-12 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MB46_06790 57a5f3705598806e2f5d414c507a86a1 547 Gene3D G3DSA:3.30.450.40 41 108 6.6E-11 T 14-10-2018 IPR029016 GAF-like domain superfamily MB46_06790 57a5f3705598806e2f5d414c507a86a1 547 Pfam PF07730 Histidine kinase 347 410 1.9E-11 T 14-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 MB46_06790 57a5f3705598806e2f5d414c507a86a1 547 Gene3D G3DSA:3.30.450.40 199 346 1.9E-6 T 14-10-2018 IPR029016 GAF-like domain superfamily MB46_06790 57a5f3705598806e2f5d414c507a86a1 547 Gene3D G3DSA:3.30.450.40 109 174 6.0E-21 T 14-10-2018 IPR029016 GAF-like domain superfamily MB46_06790 57a5f3705598806e2f5d414c507a86a1 547 SUPERFAMILY SSF55781 28 186 3.93E-24 T 14-10-2018 MB46_06790 57a5f3705598806e2f5d414c507a86a1 547 SUPERFAMILY SSF55781 200 339 8.24E-5 T 14-10-2018 MB46_06790 57a5f3705598806e2f5d414c507a86a1 547 Gene3D G3DSA:3.30.565.10 418 538 2.6E-24 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MB46_06790 57a5f3705598806e2f5d414c507a86a1 547 Pfam PF13492 GAF domain 47 166 7.3E-7 T 14-10-2018 IPR003018 GAF domain GO:0005515 MB46_06790 57a5f3705598806e2f5d414c507a86a1 547 SMART SM00065 46 175 5.2E-6 T 14-10-2018 IPR003018 GAF domain GO:0005515 MB46_00320 e33fb07533dde47bc7071cf9bfd26d7d 297 PIRSF PIRSF036628 12 286 1.6E-84 T 14-10-2018 IPR024203 5-deoxy-glucuronate isomerase, IolB GO:0008880|GO:0019310 KEGG: 00562+5.3.1.30 MB46_00320 e33fb07533dde47bc7071cf9bfd26d7d 297 TIGRFAM TIGR04378 myo_inos_iolB: 5-deoxy-glucuronate isomerase 30 281 7.7E-81 T 14-10-2018 IPR024203 5-deoxy-glucuronate isomerase, IolB GO:0008880|GO:0019310 KEGG: 00562+5.3.1.30 MB46_00320 e33fb07533dde47bc7071cf9bfd26d7d 297 Pfam PF04962 KduI/IolB family 26 280 1.6E-88 T 14-10-2018 IPR021120 KduI/IolB isomerase GO:0016861 KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 MB46_00320 e33fb07533dde47bc7071cf9bfd26d7d 297 Gene3D G3DSA:2.60.120.10 131 280 1.0E-78 T 14-10-2018 IPR014710 RmlC-like jelly roll fold MB46_00320 e33fb07533dde47bc7071cf9bfd26d7d 297 SUPERFAMILY SSF51182 22 262 1.76E-55 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily MB46_00320 e33fb07533dde47bc7071cf9bfd26d7d 297 Gene3D G3DSA:2.60.120.10 30 130 1.0E-78 T 14-10-2018 IPR014710 RmlC-like jelly roll fold MB46_06660 124d34e45d459318bc21ef616e733c3c 319 Gene3D G3DSA:1.10.10.10 1 61 2.0E-9 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_06660 124d34e45d459318bc21ef616e733c3c 319 Pfam PF13280 WYL domain 150 311 5.1E-24 T 14-10-2018 IPR026881 WYL domain MB46_06660 124d34e45d459318bc21ef616e733c3c 319 SUPERFAMILY SSF46785 2 56 1.96E-8 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_06660 124d34e45d459318bc21ef616e733c3c 319 Pfam PF08279 HTH domain 6 57 5.1E-11 T 14-10-2018 IPR013196 Helix-turn-helix, type 11 MB46_10900 c7addd79eb15519272454e0fed560fd3 322 Pfam PF00535 Glycosyl transferase family 2 12 147 1.1E-19 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MB46_10900 c7addd79eb15519272454e0fed560fd3 322 Gene3D G3DSA:3.90.550.10 5 231 3.0E-24 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MB46_10900 c7addd79eb15519272454e0fed560fd3 322 SUPERFAMILY SSF53448 11 243 3.28E-31 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MB46_04875 01ef3f5091fb996639a82947b4624979 387 SUPERFAMILY SSF50952 61 371 1.15E-41 T 14-10-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 MB46_04875 01ef3f5091fb996639a82947b4624979 387 Pfam PF07995 Glucose / Sorbosone dehydrogenase 66 371 3.8E-68 T 14-10-2018 IPR012938 Glucose/Sorbosone dehydrogenase MB46_04875 01ef3f5091fb996639a82947b4624979 387 Gene3D G3DSA:2.120.10.30 39 386 8.2E-117 T 14-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like MB46_04720 1beb64d1433d02ee124975e05403e5b4 133 PIRSF PIRSF017385 1 133 1.2E-46 T 14-10-2018 IPR021050 Cytochrome c oxidase subunit IV, actinobacteria GO:0004129|GO:0016021|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 MB46_04720 1beb64d1433d02ee124975e05403e5b4 133 Pfam PF12270 Cytochrome c oxidase subunit IV 2 132 3.3E-52 T 14-10-2018 IPR021050 Cytochrome c oxidase subunit IV, actinobacteria GO:0004129|GO:0016021|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 MB46_08655 cc51daafb1399fe32d9de13c36756a51 589 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 11 508 36.91 T 14-10-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 MB46_08655 cc51daafb1399fe32d9de13c36756a51 589 Pfam PF02355 Protein export membrane protein 322 489 4.8E-8 T 14-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial MB46_08655 cc51daafb1399fe32d9de13c36756a51 589 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 271 486 2.4E-52 T 14-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial MB46_08655 cc51daafb1399fe32d9de13c36756a51 589 Gene3D G3DSA:1.20.1640.10 317 504 3.2E-7 T 14-10-2018 MB46_08655 cc51daafb1399fe32d9de13c36756a51 589 SUPERFAMILY SSF82866 300 500 4.84E-29 T 14-10-2018 MB46_08655 cc51daafb1399fe32d9de13c36756a51 589 Gene3D G3DSA:3.30.70.3400 43 130 2.7E-18 T 14-10-2018 MB46_08655 cc51daafb1399fe32d9de13c36756a51 589 Gene3D G3DSA:3.30.1360.200 173 316 3.6E-20 T 14-10-2018 MB46_08655 cc51daafb1399fe32d9de13c36756a51 589 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 43 492 9.0E-96 T 14-10-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 MB46_09400 78c030c6518a4bce1a8817b1eda00b3f 483 SUPERFAMILY SSF48179 181 474 4.76E-114 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MB46_09400 78c030c6518a4bce1a8817b1eda00b3f 483 SUPERFAMILY SSF51735 8 181 1.25E-53 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_09400 78c030c6518a4bce1a8817b1eda00b3f 483 SMART SM01350 183 471 2.2E-190 T 14-10-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 MB46_09400 78c030c6518a4bce1a8817b1eda00b3f 483 TIGRFAM TIGR00873 gnd: 6-phosphogluconate dehydrogenase (decarboxylating) 9 471 1.3E-203 T 14-10-2018 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 MB46_09400 78c030c6518a4bce1a8817b1eda00b3f 483 Gene3D G3DSA:1.10.1040.10 185 438 9.5E-98 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MB46_09400 78c030c6518a4bce1a8817b1eda00b3f 483 ProSitePatterns PS00461 6-phosphogluconate dehydrogenase signature. 258 270 - T 14-10-2018 IPR006184 6-phosphogluconate-binding site GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 MB46_09400 78c030c6518a4bce1a8817b1eda00b3f 483 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 9 176 2.2E-49 T 14-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 MB46_09400 78c030c6518a4bce1a8817b1eda00b3f 483 PIRSF PIRSF000109 2 479 4.4E-201 T 14-10-2018 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 MB46_09400 78c030c6518a4bce1a8817b1eda00b3f 483 Gene3D G3DSA:1.20.5.320 439 473 3.0E-15 T 14-10-2018 MB46_09400 78c030c6518a4bce1a8817b1eda00b3f 483 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 183 470 7.3E-121 T 14-10-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 MB46_09400 78c030c6518a4bce1a8817b1eda00b3f 483 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 8 31 2.5E-81 T 14-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 MB46_09400 78c030c6518a4bce1a8817b1eda00b3f 483 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 254 281 2.5E-81 T 14-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 MB46_09400 78c030c6518a4bce1a8817b1eda00b3f 483 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 172 200 2.5E-81 T 14-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 MB46_09400 78c030c6518a4bce1a8817b1eda00b3f 483 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 360 382 2.5E-81 T 14-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 MB46_09400 78c030c6518a4bce1a8817b1eda00b3f 483 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 124 149 2.5E-81 T 14-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 MB46_09400 78c030c6518a4bce1a8817b1eda00b3f 483 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 71 100 2.5E-81 T 14-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 MB46_09400 78c030c6518a4bce1a8817b1eda00b3f 483 Gene3D G3DSA:3.40.50.720 3 184 1.1E-54 T 14-10-2018 MB46_09115 d4ad6979d14e187248e3a8e209c032e3 144 SUPERFAMILY SSF46458 23 143 1.46E-31 T 14-10-2018 IPR009050 Globin-like superfamily MB46_09115 d4ad6979d14e187248e3a8e209c032e3 144 Pfam PF01152 Bacterial-like globin 24 140 2.0E-30 T 14-10-2018 IPR001486 Truncated hemoglobin GO:0019825 MB46_09115 d4ad6979d14e187248e3a8e209c032e3 144 Gene3D G3DSA:1.10.490.10 21 144 4.5E-44 T 14-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 MB46_18495 4cb529b524bc05e6783388d26d5f031b 159 Pfam PF00583 Acetyltransferase (GNAT) family 67 135 1.8E-11 T 14-10-2018 IPR000182 GNAT domain MB46_18495 4cb529b524bc05e6783388d26d5f031b 159 Gene3D G3DSA:3.40.630.30 11 151 8.7E-19 T 14-10-2018 MB46_18495 4cb529b524bc05e6783388d26d5f031b 159 SUPERFAMILY SSF55729 36 155 4.53E-20 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase MB46_00845 9b39427f9f17aa970ace4b2835270377 243 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_00845 9b39427f9f17aa970ace4b2835270377 243 SMART SM00382 28 215 5.4E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_00845 9b39427f9f17aa970ace4b2835270377 243 Pfam PF00005 ABC transporter 19 167 4.4E-36 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_00845 9b39427f9f17aa970ace4b2835270377 243 PIRSF PIRSF039085 1 243 1.1E-105 T 14-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 MB46_00845 9b39427f9f17aa970ace4b2835270377 243 Gene3D G3DSA:3.40.50.300 3 243 5.5E-76 T 14-10-2018 MB46_00845 9b39427f9f17aa970ace4b2835270377 243 SUPERFAMILY SSF52540 3 230 7.14E-78 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_14450 5ec5e85bc182d47ff4c1778b9c88b362 436 Pfam PF14535 AMP-binding enzyme C-terminal domain 342 435 1.4E-23 T 14-10-2018 IPR028154 AMP-dependent ligase, C-terminal MB46_14450 5ec5e85bc182d47ff4c1778b9c88b362 436 PIRSF PIRSF006444 5 436 3.4E-193 T 14-10-2018 IPR011880 Phenylacetate-CoA ligase GO:0010124|GO:0047475 KEGG: 00360+6.2.1.30|MetaCyc: PWY-1341|MetaCyc: PWY-6318|MetaCyc: PWY-7716 MB46_14450 5ec5e85bc182d47ff4c1778b9c88b362 436 SUPERFAMILY SSF56801 27 392 4.06E-59 T 14-10-2018 MB46_14450 5ec5e85bc182d47ff4c1778b9c88b362 436 Pfam PF00501 AMP-binding enzyme 89 295 5.5E-12 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 MB46_14450 5ec5e85bc182d47ff4c1778b9c88b362 436 TIGRFAM TIGR02155 PA_CoA_ligase: phenylacetate-CoA ligase 18 435 2.8E-198 T 14-10-2018 IPR011880 Phenylacetate-CoA ligase GO:0010124|GO:0047475 KEGG: 00360+6.2.1.30|MetaCyc: PWY-1341|MetaCyc: PWY-6318|MetaCyc: PWY-7716 MB46_14450 5ec5e85bc182d47ff4c1778b9c88b362 436 Gene3D G3DSA:3.30.300.30 334 436 1.1E-29 T 14-10-2018 MB46_14450 5ec5e85bc182d47ff4c1778b9c88b362 436 Gene3D G3DSA:3.40.50.12780 4 333 1.5E-129 T 14-10-2018 MB46_03480 ef0702d64f768bcbb1ccb16d0ceecc20 398 Gene3D G3DSA:1.10.540.10 10 136 5.0E-25 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 MB46_03480 ef0702d64f768bcbb1ccb16d0ceecc20 398 Gene3D G3DSA:2.40.110.10 138 242 1.4E-29 T 14-10-2018 MB46_03480 ef0702d64f768bcbb1ccb16d0ceecc20 398 Gene3D G3DSA:1.20.140.10 246 397 1.4E-35 T 14-10-2018 MB46_03480 ef0702d64f768bcbb1ccb16d0ceecc20 398 SUPERFAMILY SSF56645 19 242 1.96E-60 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 MB46_03480 ef0702d64f768bcbb1ccb16d0ceecc20 398 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 248 391 1.3E-23 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MB46_03480 ef0702d64f768bcbb1ccb16d0ceecc20 398 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 139 232 2.5E-21 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MB46_03480 ef0702d64f768bcbb1ccb16d0ceecc20 398 SUPERFAMILY SSF47203 246 394 5.32E-36 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 MB46_03480 ef0702d64f768bcbb1ccb16d0ceecc20 398 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 141 153 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 MB46_03480 ef0702d64f768bcbb1ccb16d0ceecc20 398 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 28 132 5.0E-18 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MB46_14025 8699759e2f6740cd6a62ea817c718cc0 162 Pfam PF04461 Protein of unknown function (DUF520) 6 162 1.5E-56 T 14-10-2018 IPR007551 Protein of unknown function DUF520 MB46_14025 8699759e2f6740cd6a62ea817c718cc0 162 SUPERFAMILY SSF89963 91 162 3.66E-21 T 14-10-2018 IPR036183 YajQ-like superfamily MB46_14025 8699759e2f6740cd6a62ea817c718cc0 162 Gene3D G3DSA:3.30.70.990 12 100 3.3E-54 T 14-10-2018 IPR035570 UPF0234, N-terminal MB46_14025 8699759e2f6740cd6a62ea817c718cc0 162 Hamap MF_00632 UPF0234 protein YajQ [yajQ]. 4 162 23.051 T 14-10-2018 IPR007551 Protein of unknown function DUF520 MB46_14025 8699759e2f6740cd6a62ea817c718cc0 162 SUPERFAMILY SSF89963 6 89 9.16E-27 T 14-10-2018 IPR036183 YajQ-like superfamily MB46_14025 8699759e2f6740cd6a62ea817c718cc0 162 Gene3D G3DSA:3.30.70.860 6 162 3.3E-54 T 14-10-2018 IPR035571 UPF0234-like, C-terminal MB46_01855 4be87d29fa891f207ab49cac293746e1 359 Gene3D G3DSA:1.10.390.10 193 358 4.3E-59 T 14-10-2018 IPR027268 Peptidase M4/M1, CTD superfamily MB46_01855 4be87d29fa891f207ab49cac293746e1 359 Pfam PF01447 Thermolysin metallopeptidase, catalytic domain 103 188 1.4E-27 T 14-10-2018 IPR013856 Peptidase M4 domain GO:0004222 MB46_01855 4be87d29fa891f207ab49cac293746e1 359 SUPERFAMILY SSF55486 88 357 5.13E-76 T 14-10-2018 MB46_01855 4be87d29fa891f207ab49cac293746e1 359 Pfam PF02868 Thermolysin metallopeptidase, alpha-helical domain 191 357 8.8E-52 T 14-10-2018 IPR001570 Peptidase M4, C-terminal GO:0004222 MB46_01855 4be87d29fa891f207ab49cac293746e1 359 Gene3D G3DSA:3.10.170.10 5 192 3.9E-53 T 14-10-2018 MB46_01855 4be87d29fa891f207ab49cac293746e1 359 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 281 297 1.3E-27 T 14-10-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 MB46_01855 4be87d29fa891f207ab49cac293746e1 359 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 200 211 1.3E-27 T 14-10-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 MB46_01855 4be87d29fa891f207ab49cac293746e1 359 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 141 161 1.3E-27 T 14-10-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 MB46_01855 4be87d29fa891f207ab49cac293746e1 359 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 179 195 1.3E-27 T 14-10-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 MB46_08280 41cd0068fd9a01e5749830b8388abeb1 332 PIRSF PIRSF004486 9 327 5.2E-100 T 14-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 MB46_08280 41cd0068fd9a01e5749830b8388abeb1 332 SUPERFAMILY SSF53335 14 326 1.21E-36 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MB46_08280 41cd0068fd9a01e5749830b8388abeb1 332 SUPERFAMILY SSF81799 130 231 4.97E-35 T 14-10-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily GO:0008168 MB46_08280 41cd0068fd9a01e5749830b8388abeb1 332 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 12 325 7.7E-96 T 14-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 MB46_08280 41cd0068fd9a01e5749830b8388abeb1 332 Gene3D G3DSA:1.10.150.170 128 233 1.3E-94 T 14-10-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily GO:0008168 MB46_08280 41cd0068fd9a01e5749830b8388abeb1 332 Gene3D G3DSA:3.40.50.150 14 322 1.3E-94 T 14-10-2018 MB46_08280 41cd0068fd9a01e5749830b8388abeb1 332 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 14 326 36.301 T 14-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 MB46_08280 41cd0068fd9a01e5749830b8388abeb1 332 Pfam PF01795 MraW methylase family 13 326 4.2E-112 T 14-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 MB46_00405 935fbde217767f4b1d332e8543add86d 278 SMART SM00382 41 229 1.4E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_00405 935fbde217767f4b1d332e8543add86d 278 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_00405 935fbde217767f4b1d332e8543add86d 278 Gene3D G3DSA:3.40.50.300 17 264 6.2E-65 T 14-10-2018 MB46_00405 935fbde217767f4b1d332e8543add86d 278 SUPERFAMILY SSF52540 11 243 5.12E-59 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_00405 935fbde217767f4b1d332e8543add86d 278 Pfam PF00005 ABC transporter 34 180 7.5E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_08740 4d366336d6ae295bf70b8ffc33d084c2 168 Gene3D G3DSA:3.40.630.30 4 165 7.9E-19 T 14-10-2018 MB46_08740 4d366336d6ae295bf70b8ffc33d084c2 168 SUPERFAMILY SSF55729 23 163 1.05E-16 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase MB46_08740 4d366336d6ae295bf70b8ffc33d084c2 168 Pfam PF08445 FR47-like protein 101 160 3.7E-7 T 14-10-2018 IPR013653 FR47-like GO:0016747 MB46_11630 155cf4ec343575e0f202d78864896d70 305 Pfam PF00156 Phosphoribosyl transferase domain 201 283 7.7E-10 T 14-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 MB46_11630 155cf4ec343575e0f202d78864896d70 305 Gene3D G3DSA:3.40.50.2020 109 297 4.6E-14 T 14-10-2018 MB46_11630 155cf4ec343575e0f202d78864896d70 305 SUPERFAMILY SSF53271 133 278 9.69E-17 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like MB46_04280 d375ead7cea8cf3e88711940a0af5cda 328 SUPERFAMILY SSF47823 23 120 1.82E-12 T 14-10-2018 MB46_04280 d375ead7cea8cf3e88711940a0af5cda 328 SUPERFAMILY SSF56349 129 324 8.83E-54 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MB46_04280 d375ead7cea8cf3e88711940a0af5cda 328 Gene3D G3DSA:1.10.443.10 133 320 1.2E-60 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 MB46_04280 d375ead7cea8cf3e88711940a0af5cda 328 TIGRFAM TIGR02225 recomb_XerD: tyrosine recombinase XerD 26 326 1.4E-100 T 14-10-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 MB46_04280 d375ead7cea8cf3e88711940a0af5cda 328 Hamap MF_01807 Tyrosine recombinase XerD [xerD]. 20 326 54.126 T 14-10-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 MB46_04280 d375ead7cea8cf3e88711940a0af5cda 328 Gene3D G3DSA:1.10.150.130 21 121 3.2E-13 T 14-10-2018 IPR010998 Integrase/recombinase, N-terminal MB46_04280 d375ead7cea8cf3e88711940a0af5cda 328 Pfam PF00589 Phage integrase family 136 311 4.6E-44 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MB46_04280 d375ead7cea8cf3e88711940a0af5cda 328 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 24 111 1.1E-12 T 14-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 MB46_04280 d375ead7cea8cf3e88711940a0af5cda 328 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 22 326 53.263 T 14-10-2018 IPR023009 Tyrosine recombinase XerC/XerD MB46_02040 0d88f3d3008adc5adc5eff9f189cf565 281 PIRSF PIRSF009160 1 281 9.2E-71 T 14-10-2018 IPR010539 Protein of unknown function UCP009160 MB46_02040 0d88f3d3008adc5adc5eff9f189cf565 281 Pfam PF12811 Bax inhibitor 1 like 25 278 2.6E-82 T 14-10-2018 IPR010539 Protein of unknown function UCP009160 MB46_02145 3bf98366403e78581ee1bdb1194bab60 169 Pfam PF01478 Type IV leader peptidase family 25 135 1.5E-15 T 14-10-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 MB46_02145 3bf98366403e78581ee1bdb1194bab60 169 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 33 50 6.5E-5 T 14-10-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial MB46_02145 3bf98366403e78581ee1bdb1194bab60 169 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 101 112 6.5E-5 T 14-10-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial MB46_02145 3bf98366403e78581ee1bdb1194bab60 169 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 90 100 6.5E-5 T 14-10-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial MB46_17695 0fe1df0e3dc2f7400e7bf9f43716fb05 379 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 21 136 7.2E-24 T 14-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 MB46_17695 0fe1df0e3dc2f7400e7bf9f43716fb05 379 SUPERFAMILY SSF55347 146 285 2.78E-26 T 14-10-2018 MB46_17695 0fe1df0e3dc2f7400e7bf9f43716fb05 379 Gene3D G3DSA:3.30.360.10 144 347 3.1E-77 T 14-10-2018 MB46_17695 0fe1df0e3dc2f7400e7bf9f43716fb05 379 Gene3D G3DSA:3.40.50.720 23 326 3.1E-77 T 14-10-2018 MB46_17695 0fe1df0e3dc2f7400e7bf9f43716fb05 379 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 152 258 3.9E-8 T 14-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 MB46_17695 0fe1df0e3dc2f7400e7bf9f43716fb05 379 SUPERFAMILY SSF51735 16 173 7.17E-42 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_13105 538a02914df08934746168eb706ca575 192 SUPERFAMILY SSF46689 3 69 9.23E-15 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MB46_13105 538a02914df08934746168eb706ca575 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 2.0E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MB46_13105 538a02914df08934746168eb706ca575 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 2.0E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MB46_13105 538a02914df08934746168eb706ca575 192 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 58 3.6E-13 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MB46_13105 538a02914df08934746168eb706ca575 192 Gene3D G3DSA:1.10.357.10 5 188 2.2E-27 T 14-10-2018 MB46_13125 d7603e38d52d15bad288b263502fbc1f 302 Gene3D G3DSA:1.10.3720.10 18 293 5.4E-51 T 14-10-2018 IPR035906 MetI-like superfamily MB46_13125 d7603e38d52d15bad288b263502fbc1f 302 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 116 277 1.3E-11 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_13125 d7603e38d52d15bad288b263502fbc1f 302 SUPERFAMILY SSF161098 25 302 3.92E-53 T 14-10-2018 IPR035906 MetI-like superfamily MB46_00395 76ac428f174bc46b8cecf6f70d3f2e57 362 Pfam PF01032 FecCD transport family 46 356 2.5E-86 T 14-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 MB46_00395 76ac428f174bc46b8cecf6f70d3f2e57 362 Gene3D G3DSA:1.10.3470.10 32 361 6.2E-89 T 14-10-2018 IPR037294 ABC transporter, BtuC-like MB46_00395 76ac428f174bc46b8cecf6f70d3f2e57 362 SUPERFAMILY SSF81345 31 356 3.53E-75 T 14-10-2018 IPR037294 ABC transporter, BtuC-like MB46_04470 7663bd3cd9d5d2092ccb82c8fd050dba 220 SUPERFAMILY SSF69593 13 192 3.4E-31 T 14-10-2018 MB46_04470 7663bd3cd9d5d2092ccb82c8fd050dba 220 Pfam PF01553 Acyltransferase 18 137 2.9E-16 T 14-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 MB46_04470 7663bd3cd9d5d2092ccb82c8fd050dba 220 SMART SM00563 31 140 2.1E-19 T 14-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 MB46_05150 9a2a03f7100db42dd18e0bfd527dd078 255 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 4 246 4.5E-100 T 14-10-2018 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524 MB46_05150 9a2a03f7100db42dd18e0bfd527dd078 255 SUPERFAMILY SSF52540 4 234 4.17E-39 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_05150 9a2a03f7100db42dd18e0bfd527dd078 255 SMART SM00382 32 226 0.0041 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_05150 9a2a03f7100db42dd18e0bfd527dd078 255 Gene3D G3DSA:3.40.50.300 1 247 4.6E-51 T 14-10-2018 MB46_05150 9a2a03f7100db42dd18e0bfd527dd078 255 Pfam PF00005 ABC transporter 23 174 1.5E-21 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_16320 8c8b8cda6459d1b5672495c225e45202 459 Pfam PF03796 DnaB-like helicase C terminal domain 196 450 5.8E-106 T 14-10-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 MB46_16320 8c8b8cda6459d1b5672495c225e45202 459 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 21 452 1.0E-166 T 14-10-2018 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 MB46_16320 8c8b8cda6459d1b5672495c225e45202 459 Gene3D G3DSA:3.40.50.300 179 456 5.3E-104 T 14-10-2018 MB46_16320 8c8b8cda6459d1b5672495c225e45202 459 SUPERFAMILY SSF48024 19 130 6.67E-36 T 14-10-2018 IPR036185 DNA helicase, DnaB-like, N-terminal domain superfamily GO:0003678|GO:0005524|GO:0006260 MB46_16320 8c8b8cda6459d1b5672495c225e45202 459 SUPERFAMILY SSF52540 194 442 4.28E-52 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_16320 8c8b8cda6459d1b5672495c225e45202 459 Pfam PF00772 DnaB-like helicase N terminal domain 21 121 1.0E-33 T 14-10-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 MB46_16320 8c8b8cda6459d1b5672495c225e45202 459 Gene3D G3DSA:1.10.860.10 16 177 5.0E-59 T 14-10-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal MB46_07140 bcd9a818e4f1de3c4e425f1b0835cb72 221 SUPERFAMILY SSF52172 1 108 5.12E-19 T 14-10-2018 IPR011006 CheY-like superfamily MB46_07140 bcd9a818e4f1de3c4e425f1b0835cb72 221 SMART SM00421 149 212 4.1E-10 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_07140 bcd9a818e4f1de3c4e425f1b0835cb72 221 Pfam PF00196 Bacterial regulatory proteins, luxR family 151 196 4.3E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_07140 bcd9a818e4f1de3c4e425f1b0835cb72 221 Pfam PF00072 Response regulator receiver domain 3 112 5.2E-18 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MB46_07140 bcd9a818e4f1de3c4e425f1b0835cb72 221 Gene3D G3DSA:3.40.50.12740 1 214 1.1E-42 T 14-10-2018 MB46_07140 bcd9a818e4f1de3c4e425f1b0835cb72 221 SUPERFAMILY SSF46894 137 197 2.62E-12 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MB46_07140 bcd9a818e4f1de3c4e425f1b0835cb72 221 SMART SM00448 1 120 8.7E-8 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MB46_07140 bcd9a818e4f1de3c4e425f1b0835cb72 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 152 166 5.1E-8 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_07140 bcd9a818e4f1de3c4e425f1b0835cb72 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 166 182 5.1E-8 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_07140 bcd9a818e4f1de3c4e425f1b0835cb72 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 182 194 5.1E-8 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_11835 fe382ab0c162f5b4192c35052e1e469a 136 SUPERFAMILY SSF50331 10 127 7.53E-17 T 14-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal MB46_11835 fe382ab0c162f5b4192c35052e1e469a 136 Pfam PF03459 TOBE domain 65 127 7.0E-9 T 14-10-2018 IPR005116 Transport-associated OB, type 1 MB46_11835 fe382ab0c162f5b4192c35052e1e469a 136 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 4 34 4.9E-8 T 14-10-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 MB46_11835 fe382ab0c162f5b4192c35052e1e469a 136 Pfam PF12728 Helix-turn-helix domain 4 53 2.7E-9 T 14-10-2018 MB46_11835 fe382ab0c162f5b4192c35052e1e469a 136 Gene3D G3DSA:1.10.1660.10 4 59 9.2E-8 T 14-10-2018 MB46_11835 fe382ab0c162f5b4192c35052e1e469a 136 Gene3D G3DSA:2.40.50.100 64 128 2.7E-16 T 14-10-2018 MB46_19475 bbba23c9d9c7e90aacc9638529676fae 222 SUPERFAMILY SSF88659 127 182 3.55E-9 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like MB46_19475 bbba23c9d9c7e90aacc9638529676fae 222 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 32 182 4.3E-19 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 MB46_19475 bbba23c9d9c7e90aacc9638529676fae 222 Gene3D G3DSA:1.10.1740.10 15 101 6.6E-15 T 14-10-2018 MB46_19475 bbba23c9d9c7e90aacc9638529676fae 222 Pfam PF04542 Sigma-70 region 2 36 97 1.4E-10 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 MB46_19475 bbba23c9d9c7e90aacc9638529676fae 222 SUPERFAMILY SSF88946 17 110 1.73E-19 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 MB46_19475 bbba23c9d9c7e90aacc9638529676fae 222 Gene3D G3DSA:1.10.10.10 106 186 1.9E-9 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_03795 fd1f55099e700be0fb7db4d87e9d589e 392 SUPERFAMILY SSF55729 12 183 5.22E-24 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase MB46_03795 fd1f55099e700be0fb7db4d87e9d589e 392 Gene3D G3DSA:3.40.630.30 7 198 1.9E-25 T 14-10-2018 MB46_03795 fd1f55099e700be0fb7db4d87e9d589e 392 SUPERFAMILY SSF55729 202 372 1.22E-32 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase MB46_03795 fd1f55099e700be0fb7db4d87e9d589e 392 Pfam PF13302 Acetyltransferase (GNAT) domain 19 162 4.0E-15 T 14-10-2018 IPR000182 GNAT domain MB46_03795 fd1f55099e700be0fb7db4d87e9d589e 392 Pfam PF13302 Acetyltransferase (GNAT) domain 212 349 1.7E-15 T 14-10-2018 IPR000182 GNAT domain MB46_03795 fd1f55099e700be0fb7db4d87e9d589e 392 Gene3D G3DSA:3.40.630.30 199 384 8.9E-34 T 14-10-2018 MB46_19395 5f22fa2d1109d61a4dc738ec784f2df3 1519 Gene3D G3DSA:1.50.10.100 515 748 5.2E-25 T 14-10-2018 IPR008929 Chondroitin AC/alginate lyase Reactome: R-HSA-2022923 MB46_19395 5f22fa2d1109d61a4dc738ec784f2df3 1519 Gene3D G3DSA:2.60.120.260 184 338 2.8E-19 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily MB46_19395 5f22fa2d1109d61a4dc738ec784f2df3 1519 Gene3D G3DSA:2.60.120.260 34 183 1.3E-17 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily MB46_19395 5f22fa2d1109d61a4dc738ec784f2df3 1519 Gene3D G3DSA:2.60.40.10 339 442 1.5E-6 T 14-10-2018 IPR013783 Immunoglobulin-like fold MB46_19395 5f22fa2d1109d61a4dc738ec784f2df3 1519 SUPERFAMILY SSF48230 570 724 3.02E-7 T 14-10-2018 IPR008929 Chondroitin AC/alginate lyase Reactome: R-HSA-2022923 MB46_10560 d402aedddfb16217729246212ce4a1ad 336 SUPERFAMILY SSF56300 3 260 1.49E-38 T 14-10-2018 MB46_10560 d402aedddfb16217729246212ce4a1ad 336 Pfam PF00149 Calcineurin-like phosphoesterase 4 213 1.6E-10 T 14-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 MB46_10560 d402aedddfb16217729246212ce4a1ad 336 Gene3D G3DSA:3.60.21.10 1 278 1.7E-66 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like MB46_02755 4dc237538252fea93a404102d2ae3c7c 618 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 124 206 6.5E-27 T 14-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MB46_02755 4dc237538252fea93a404102d2ae3c7c 618 SUPERFAMILY SSF53738 254 356 1.73E-20 T 14-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MB46_02755 4dc237538252fea93a404102d2ae3c7c 618 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 371 492 1.6E-12 T 14-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MB46_02755 4dc237538252fea93a404102d2ae3c7c 618 Gene3D G3DSA:3.40.120.10 253 367 8.4E-22 T 14-10-2018 MB46_02755 4dc237538252fea93a404102d2ae3c7c 618 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 178 192 2.6E-6 T 14-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MB46_02755 4dc237538252fea93a404102d2ae3c7c 618 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 274 293 2.6E-6 T 14-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MB46_02755 4dc237538252fea93a404102d2ae3c7c 618 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 341 356 2.6E-6 T 14-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MB46_02755 4dc237538252fea93a404102d2ae3c7c 618 SUPERFAMILY SSF53738 349 497 2.35E-24 T 14-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MB46_02755 4dc237538252fea93a404102d2ae3c7c 618 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 179 188 - T 14-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MB46_02755 4dc237538252fea93a404102d2ae3c7c 618 Gene3D G3DSA:3.40.120.10 368 498 1.1E-24 T 14-10-2018 MB46_02755 4dc237538252fea93a404102d2ae3c7c 618 SUPERFAMILY SSF53738 52 266 5.89E-35 T 14-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MB46_02755 4dc237538252fea93a404102d2ae3c7c 618 SUPERFAMILY SSF55957 501 586 2.22E-15 T 14-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MB46_02755 4dc237538252fea93a404102d2ae3c7c 618 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 256 356 3.0E-24 T 14-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MB46_02755 4dc237538252fea93a404102d2ae3c7c 618 Gene3D G3DSA:3.30.310.50 503 601 5.4E-8 T 14-10-2018 MB46_02755 4dc237538252fea93a404102d2ae3c7c 618 Gene3D G3DSA:3.40.120.10 54 224 4.1E-38 T 14-10-2018 MB46_02755 4dc237538252fea93a404102d2ae3c7c 618 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 505 580 4.0E-10 T 14-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MB46_05010 777c7ce0b495aab8d441479425a38f94 646 SUPERFAMILY SSF52540 392 634 3.33E-89 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_05010 777c7ce0b495aab8d441479425a38f94 646 SUPERFAMILY SSF90123 25 381 1.22E-79 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MB46_05010 777c7ce0b495aab8d441479425a38f94 646 Gene3D G3DSA:3.40.50.300 396 639 1.5E-87 T 14-10-2018 MB46_05010 777c7ce0b495aab8d441479425a38f94 646 ProSitePatterns PS00211 ABC transporters family signature. 536 550 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_05010 777c7ce0b495aab8d441479425a38f94 646 Pfam PF00664 ABC transporter transmembrane region 45 353 4.3E-55 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 MB46_05010 777c7ce0b495aab8d441479425a38f94 646 SMART SM00382 424 610 3.8E-17 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_05010 777c7ce0b495aab8d441479425a38f94 646 Pfam PF00005 ABC transporter 416 564 3.6E-31 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_09940 066adbc480a2ec289bd0e471cc40fe9a 490 SUPERFAMILY SSF53732 12 484 4.84E-157 T 14-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 MB46_09940 066adbc480a2ec289bd0e471cc40fe9a 490 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 12 482 58.624 T 14-10-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 MB46_09940 066adbc480a2ec289bd0e471cc40fe9a 490 ProSitePatterns PS00450 Aconitase family signature 1. 355 371 - T 14-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 MB46_09940 066adbc480a2ec289bd0e471cc40fe9a 490 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 13 475 3.2E-220 T 14-10-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 MB46_09940 066adbc480a2ec289bd0e471cc40fe9a 490 Pfam PF00330 Aconitase family (aconitate hydratase) 18 473 2.2E-152 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MB46_09940 066adbc480a2ec289bd0e471cc40fe9a 490 Gene3D G3DSA:3.30.499.20 15 302 5.9E-96 T 14-10-2018 MB46_09940 066adbc480a2ec289bd0e471cc40fe9a 490 ProSitePatterns PS01244 Aconitase family signature 2. 415 428 - T 14-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 MB46_09940 066adbc480a2ec289bd0e471cc40fe9a 490 Gene3D G3DSA:3.30.499.10 342 489 4.0E-47 T 14-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 MB46_09940 066adbc480a2ec289bd0e471cc40fe9a 490 PRINTS PR00415 Aconitase family signature 98 111 2.9E-45 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MB46_09940 066adbc480a2ec289bd0e471cc40fe9a 490 PRINTS PR00415 Aconitase family signature 149 164 2.9E-45 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MB46_09940 066adbc480a2ec289bd0e471cc40fe9a 490 PRINTS PR00415 Aconitase family signature 211 224 2.9E-45 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MB46_09940 066adbc480a2ec289bd0e471cc40fe9a 490 PRINTS PR00415 Aconitase family signature 359 370 2.9E-45 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MB46_09940 066adbc480a2ec289bd0e471cc40fe9a 490 PRINTS PR00415 Aconitase family signature 225 238 2.9E-45 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MB46_09940 066adbc480a2ec289bd0e471cc40fe9a 490 PRINTS PR00415 Aconitase family signature 302 316 2.9E-45 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MB46_09940 066adbc480a2ec289bd0e471cc40fe9a 490 PRINTS PR00415 Aconitase family signature 135 148 2.9E-45 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MB46_09940 066adbc480a2ec289bd0e471cc40fe9a 490 PRINTS PR00415 Aconitase family signature 124 132 2.9E-45 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MB46_09940 066adbc480a2ec289bd0e471cc40fe9a 490 PRINTS PR00415 Aconitase family signature 415 428 2.9E-45 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MB46_05575 f0b732291d07e682bdc405117eba9522 313 SUPERFAMILY SSF46689 211 257 6.61E-6 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MB46_05575 f0b732291d07e682bdc405117eba9522 313 Pfam PF12852 Cupin 2 190 1.3E-38 T 14-10-2018 IPR032783 AraC-type transcription regulator, ligand-binding domain MB46_05575 f0b732291d07e682bdc405117eba9522 313 SUPERFAMILY SSF46689 259 309 3.18E-11 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MB46_05575 f0b732291d07e682bdc405117eba9522 313 Pfam PF12833 Helix-turn-helix domain 230 308 2.5E-19 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MB46_05575 f0b732291d07e682bdc405117eba9522 313 Gene3D G3DSA:1.10.10.60 207 312 4.2E-25 T 14-10-2018 MB46_05575 f0b732291d07e682bdc405117eba9522 313 SMART SM00342 223 306 4.6E-29 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MB46_12335 db052fcb5169ddfff0753cb2d810fa62 490 SMART SM00955 53 374 7.4E-47 T 14-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 MB46_12335 db052fcb5169ddfff0753cb2d810fa62 490 SUPERFAMILY SSF50249 23 416 3.66E-81 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold MB46_12335 db052fcb5169ddfff0753cb2d810fa62 490 Pfam PF00773 RNB domain 55 365 4.3E-40 T 14-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 MB46_13650 f9ad9ee218ad30c9846b90fe4e20c14d 747 SUPERFAMILY SSF56024 557 735 1.03E-62 T 14-10-2018 MB46_13650 f9ad9ee218ad30c9846b90fe4e20c14d 747 PIRSF PIRSF015589 31 746 3.1E-271 T 14-10-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 MB46_13650 f9ad9ee218ad30c9846b90fe4e20c14d 747 Gene3D G3DSA:3.30.870.10 374 556 5.1E-73 T 14-10-2018 MB46_13650 f9ad9ee218ad30c9846b90fe4e20c14d 747 Pfam PF13089 Polyphosphate kinase N-terminal domain 55 161 7.0E-36 T 14-10-2018 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 MB46_13650 f9ad9ee218ad30c9846b90fe4e20c14d 747 Gene3D G3DSA:3.30.1840.10 47 364 6.9E-110 T 14-10-2018 IPR036830 Polyphosphate kinase middle domain superfamily KEGG: 00190+2.7.4.1 MB46_13650 f9ad9ee218ad30c9846b90fe4e20c14d 747 SUPERFAMILY SSF56024 382 551 7.85E-56 T 14-10-2018 MB46_13650 f9ad9ee218ad30c9846b90fe4e20c14d 747 TIGRFAM TIGR03705 poly_P_kin: polyphosphate kinase 1 54 724 1.2E-247 T 14-10-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 MB46_13650 f9ad9ee218ad30c9846b90fe4e20c14d 747 Gene3D G3DSA:3.30.870.10 557 737 5.0E-60 T 14-10-2018 MB46_13650 f9ad9ee218ad30c9846b90fe4e20c14d 747 Pfam PF13090 Polyphosphate kinase C-terminal domain 386 731 8.9E-150 T 14-10-2018 IPR025200 Polyphosphate kinase C-terminal domain KEGG: 00190+2.7.4.1 MB46_13650 f9ad9ee218ad30c9846b90fe4e20c14d 747 SUPERFAMILY SSF140356 52 155 2.49E-35 T 14-10-2018 IPR036832 Polyphosphate kinase N-terminal domain superfamily KEGG: 00190+2.7.4.1 MB46_13650 f9ad9ee218ad30c9846b90fe4e20c14d 747 SUPERFAMILY SSF143724 158 364 1.1E-62 T 14-10-2018 MB46_13650 f9ad9ee218ad30c9846b90fe4e20c14d 747 Hamap MF_00347 Polyphosphate kinase [ppk]. 52 740 28.328 T 14-10-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 MB46_13650 f9ad9ee218ad30c9846b90fe4e20c14d 747 Pfam PF02503 Polyphosphate kinase middle domain 173 370 1.2E-61 T 14-10-2018 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 MB46_01640 adbbd438a4e6ce462ab8082f0eb1698b 572 SUPERFAMILY SSF52540 299 541 4.14E-65 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_01640 adbbd438a4e6ce462ab8082f0eb1698b 572 Gene3D G3DSA:3.40.50.300 296 565 2.7E-79 T 14-10-2018 MB46_01640 adbbd438a4e6ce462ab8082f0eb1698b 572 Gene3D G3DSA:3.40.50.300 3 294 6.2E-80 T 14-10-2018 MB46_01640 adbbd438a4e6ce462ab8082f0eb1698b 572 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 521 553 5.7E-5 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MB46_01640 adbbd438a4e6ce462ab8082f0eb1698b 572 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 240 272 4.6E-6 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MB46_01640 adbbd438a4e6ce462ab8082f0eb1698b 572 ProSitePatterns PS00211 ABC transporters family signature. 442 456 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_01640 adbbd438a4e6ce462ab8082f0eb1698b 572 ProSitePatterns PS00211 ABC transporters family signature. 161 175 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_01640 adbbd438a4e6ce462ab8082f0eb1698b 572 Pfam PF00005 ABC transporter 320 470 7.4E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_01640 adbbd438a4e6ce462ab8082f0eb1698b 572 SMART SM00382 36 238 4.1E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_01640 adbbd438a4e6ce462ab8082f0eb1698b 572 SMART SM00382 328 519 1.1E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_01640 adbbd438a4e6ce462ab8082f0eb1698b 572 SUPERFAMILY SSF52540 5 260 2.43E-59 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_01640 adbbd438a4e6ce462ab8082f0eb1698b 572 Pfam PF00005 ABC transporter 28 188 5.5E-25 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_09025 b3be8a7589109943d91264d943496798 273 Gene3D G3DSA:3.40.50.1110 2 195 7.6E-26 T 14-10-2018 IPR036514 SGNH hydrolase superfamily MB46_09025 b3be8a7589109943d91264d943496798 273 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 11 184 2.1E-22 T 14-10-2018 IPR013830 SGNH hydrolase-type esterase domain MB46_09025 b3be8a7589109943d91264d943496798 273 SUPERFAMILY SSF52266 5 194 1.31E-33 T 14-10-2018 MB46_12585 e85fd64fd4f132ed62cf8b1781b702d4 291 Gene3D G3DSA:3.40.50.1820 36 284 4.0E-53 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_12585 e85fd64fd4f132ed62cf8b1781b702d4 291 SUPERFAMILY SSF53474 16 273 1.04E-37 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_12585 e85fd64fd4f132ed62cf8b1781b702d4 291 Pfam PF07859 alpha/beta hydrolase fold 65 262 3.7E-32 T 14-10-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0016787 MB46_12585 e85fd64fd4f132ed62cf8b1781b702d4 291 ProSitePatterns PS01174 Lipolytic enzymes "G-D-X-G" family, putative serine active site. 130 142 - T 14-10-2018 IPR033140 Lipase, GDXG, putative serine active site MB46_18470 d6c3a27741e1d70eedcb32e935647a6a 172 Gene3D G3DSA:1.10.10.10 83 171 5.0E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_18470 d6c3a27741e1d70eedcb32e935647a6a 172 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 13 167 2.0E-30 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 MB46_18470 d6c3a27741e1d70eedcb32e935647a6a 172 Pfam PF08281 Sigma-70, region 4 111 164 1.3E-15 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MB46_18470 d6c3a27741e1d70eedcb32e935647a6a 172 Gene3D G3DSA:1.10.1740.10 1 82 1.1E-21 T 14-10-2018 MB46_18470 d6c3a27741e1d70eedcb32e935647a6a 172 SUPERFAMILY SSF88659 109 169 3.92E-15 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like MB46_18470 d6c3a27741e1d70eedcb32e935647a6a 172 Pfam PF04542 Sigma-70 region 2 17 83 5.6E-14 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 MB46_18470 d6c3a27741e1d70eedcb32e935647a6a 172 SUPERFAMILY SSF88946 2 98 6.44E-25 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 MB46_18470 d6c3a27741e1d70eedcb32e935647a6a 172 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 39 70 - T 14-10-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MB46_00085 898cb150557ff35f0d02170836761f63 266 Pfam PF02358 Trehalose-phosphatase 29 235 1.6E-29 T 14-10-2018 IPR003337 Trehalose-phosphatase GO:0003824|GO:0005992 MB46_00085 898cb150557ff35f0d02170836761f63 266 SUPERFAMILY SSF56784 26 255 1.53E-36 T 14-10-2018 IPR036412 HAD-like superfamily MB46_00085 898cb150557ff35f0d02170836761f63 266 Gene3D G3DSA:3.40.50.1000 27 241 2.1E-47 T 14-10-2018 IPR023214 HAD superfamily MB46_00085 898cb150557ff35f0d02170836761f63 266 Gene3D G3DSA:3.30.70.1020 109 185 2.1E-47 T 14-10-2018 MB46_00085 898cb150557ff35f0d02170836761f63 266 TIGRFAM TIGR00685 T6PP: trehalose-phosphatase 27 255 9.2E-31 T 14-10-2018 IPR003337 Trehalose-phosphatase GO:0003824|GO:0005992 MB46_00085 898cb150557ff35f0d02170836761f63 266 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 26 221 2.1E-12 T 14-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 MB46_19450 d75331e07aac37d13d12d0c1f83e7c8c 1134 Gene3D G3DSA:2.60.40.10 982 1091 8.4E-9 T 14-10-2018 IPR013783 Immunoglobulin-like fold MB46_19450 d75331e07aac37d13d12d0c1f83e7c8c 1134 Gene3D G3DSA:2.60.40.740 540 665 1.5E-6 T 14-10-2018 MB46_19450 d75331e07aac37d13d12d0c1f83e7c8c 1134 Pfam PF01345 Domain of unknown function DUF11 542 647 8.3E-7 T 14-10-2018 IPR001434 Domain of unknown function DUF11 MB46_19450 d75331e07aac37d13d12d0c1f83e7c8c 1134 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 868 897 1.6E-5 T 14-10-2018 IPR001434 Domain of unknown function DUF11 MB46_04435 e7f274b84655108d81c79b775c478f8b 248 Gene3D G3DSA:3.40.50.300 14 242 3.2E-51 T 14-10-2018 MB46_04435 e7f274b84655108d81c79b775c478f8b 248 Pfam PF00005 ABC transporter 41 178 1.2E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_04435 e7f274b84655108d81c79b775c478f8b 248 SMART SM00382 47 229 4.7E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_04435 e7f274b84655108d81c79b775c478f8b 248 SUPERFAMILY SSF52540 22 229 2.85E-45 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_04435 e7f274b84655108d81c79b775c478f8b 248 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_09785 bb957ffd82211bc82ea826d5c355b0f9 219 Pfam PF05430 S-adenosyl-L-methionine-dependent methyltransferase 77 138 2.0E-4 T 14-10-2018 IPR008471 MnmC-like methyltransferase GO:0016645|GO:0055114 MetaCyc: PWY-7892 MB46_09785 bb957ffd82211bc82ea826d5c355b0f9 219 Gene3D G3DSA:3.40.50.150 1 219 5.0E-47 T 14-10-2018 MB46_09785 bb957ffd82211bc82ea826d5c355b0f9 219 SUPERFAMILY SSF53335 12 195 3.04E-25 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MB46_04990 7caa1fb05d9716006f970cd99efcd421 845 SUPERFAMILY SSF52540 47 380 1.92E-42 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_04990 7caa1fb05d9716006f970cd99efcd421 845 Gene3D G3DSA:3.40.50.300 216 388 1.4E-38 T 14-10-2018 MB46_04990 7caa1fb05d9716006f970cd99efcd421 845 Pfam PF00270 DEAD/DEAH box helicase 37 184 4.5E-12 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MB46_04990 7caa1fb05d9716006f970cd99efcd421 845 SMART SM00490 277 367 2.2E-12 T 14-10-2018 IPR001650 Helicase, C-terminal MB46_04990 7caa1fb05d9716006f970cd99efcd421 845 Pfam PF00271 Helicase conserved C-terminal domain 288 367 1.0E-5 T 14-10-2018 IPR001650 Helicase, C-terminal MB46_04990 7caa1fb05d9716006f970cd99efcd421 845 SMART SM00487 31 214 7.9E-23 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MB46_04990 7caa1fb05d9716006f970cd99efcd421 845 Gene3D G3DSA:3.40.50.300 30 208 6.5E-39 T 14-10-2018 MB46_04990 7caa1fb05d9716006f970cd99efcd421 845 Pfam PF12029 Domain of unknown function (DUF3516) 378 838 9.8E-202 T 14-10-2018 IPR021904 Protein of unknown function DUF3516 MB46_08515 bbb4a4b0496b96ccfd861851c3735735 187 SUPERFAMILY SSF50249 129 185 3.26E-16 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold MB46_08515 bbb4a4b0496b96ccfd861851c3735735 187 Gene3D G3DSA:2.30.30.30 1 62 4.5E-28 T 14-10-2018 IPR014722 Ribosomal protein L2, domain 2 MB46_08515 bbb4a4b0496b96ccfd861851c3735735 187 SMART SM01185 67 121 1.2E-25 T 14-10-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 MB46_08515 bbb4a4b0496b96ccfd861851c3735735 187 Hamap MF_00141 Elongation factor P [efp]. 1 185 47.444 T 14-10-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 MB46_08515 bbb4a4b0496b96ccfd861851c3735735 187 Pfam PF09285 Elongation factor P, C-terminal 129 184 1.5E-23 T 14-10-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 MB46_08515 bbb4a4b0496b96ccfd861851c3735735 187 SUPERFAMILY SSF50104 2 63 4.06E-20 T 14-10-2018 IPR008991 Translation protein SH3-like domain superfamily MB46_08515 bbb4a4b0496b96ccfd861851c3735735 187 SMART SM00841 129 184 1.9E-29 T 14-10-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 MB46_08515 bbb4a4b0496b96ccfd861851c3735735 187 TIGRFAM TIGR00038 efp: translation elongation factor P 3 185 6.5E-76 T 14-10-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 MB46_08515 bbb4a4b0496b96ccfd861851c3735735 187 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 3 59 2.0E-26 T 14-10-2018 IPR013185 Translation elongation factor, KOW-like MB46_08515 bbb4a4b0496b96ccfd861851c3735735 187 Gene3D G3DSA:2.40.50.140 64 127 1.2E-23 T 14-10-2018 MB46_08515 bbb4a4b0496b96ccfd861851c3735735 187 PIRSF PIRSF005901 1 186 4.6E-65 T 14-10-2018 IPR020599 Translation elongation factor P/YeiP MB46_08515 bbb4a4b0496b96ccfd861851c3735735 187 Pfam PF01132 Elongation factor P (EF-P) OB domain 69 121 4.6E-21 T 14-10-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 MB46_08515 bbb4a4b0496b96ccfd861851c3735735 187 SUPERFAMILY SSF50249 65 126 3.47E-17 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold MB46_08515 bbb4a4b0496b96ccfd861851c3735735 187 Gene3D G3DSA:2.40.50.140 128 186 8.8E-24 T 14-10-2018 MB46_18415 541c2b5c02c2e05baf76ad119f419bb2 267 Pfam PF07920 Protein of unknown function (DUF1684) 128 264 8.3E-31 T 14-10-2018 IPR012467 Protein of unknown function DUF1684 MB46_08495 85e268f71ef3a3637d48049b2f139a8e 349 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 2 316 2.3E-84 T 14-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MB46_08495 85e268f71ef3a3637d48049b2f139a8e 349 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 1 318 39.396 T 14-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MB46_08495 85e268f71ef3a3637d48049b2f139a8e 349 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 2 146 7.6E-43 T 14-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 MB46_08495 85e268f71ef3a3637d48049b2f139a8e 349 SUPERFAMILY SSF53671 1 317 8.9E-87 T 14-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 MB46_08495 85e268f71ef3a3637d48049b2f139a8e 349 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 164 315 1.1E-16 T 14-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 MB46_08495 85e268f71ef3a3637d48049b2f139a8e 349 Gene3D G3DSA:3.40.50.1370 134 295 2.0E-86 T 14-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 MB46_08495 85e268f71ef3a3637d48049b2f139a8e 349 Gene3D G3DSA:3.40.50.1370 7 310 2.0E-86 T 14-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 MB46_08495 85e268f71ef3a3637d48049b2f139a8e 349 PRINTS PR00101 Aspartate carbamoyltransferase signature 273 278 5.6E-29 T 14-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MB46_08495 85e268f71ef3a3637d48049b2f139a8e 349 PRINTS PR00101 Aspartate carbamoyltransferase signature 297 311 5.6E-29 T 14-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MB46_08495 85e268f71ef3a3637d48049b2f139a8e 349 PRINTS PR00101 Aspartate carbamoyltransferase signature 38 60 5.6E-29 T 14-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MB46_08495 85e268f71ef3a3637d48049b2f139a8e 349 PRINTS PR00101 Aspartate carbamoyltransferase signature 228 237 5.6E-29 T 14-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MB46_08495 85e268f71ef3a3637d48049b2f139a8e 349 PRINTS PR00101 Aspartate carbamoyltransferase signature 76 85 5.6E-29 T 14-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MB46_08495 85e268f71ef3a3637d48049b2f139a8e 349 PRINTS PR00101 Aspartate carbamoyltransferase signature 133 150 5.6E-29 T 14-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MB46_08495 85e268f71ef3a3637d48049b2f139a8e 349 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 48 55 - T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MB46_08495 85e268f71ef3a3637d48049b2f139a8e 349 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 281 304 4.0E-20 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MB46_08495 85e268f71ef3a3637d48049b2f139a8e 349 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 48 67 4.0E-20 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MB46_08495 85e268f71ef3a3637d48049b2f139a8e 349 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 134 145 4.0E-20 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MB46_08495 85e268f71ef3a3637d48049b2f139a8e 349 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 269 278 4.0E-20 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MB46_11635 c58972b9eaf30f65a2a94f7dcb15e563 570 SMART SM00909 205 298 1.1E-8 T 14-10-2018 IPR019606 GerMN domain MB46_11635 c58972b9eaf30f65a2a94f7dcb15e563 570 SUPERFAMILY SSF50969 341 496 2.63E-8 T 14-10-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like MB46_11635 c58972b9eaf30f65a2a94f7dcb15e563 570 Pfam PF10646 Sporulation and spore germination 180 294 3.8E-13 T 14-10-2018 IPR019606 GerMN domain MB46_11635 c58972b9eaf30f65a2a94f7dcb15e563 570 Pfam PF10647 Lipoprotein LpqB beta-propeller domain 323 564 8.4E-33 T 14-10-2018 IPR018910 Lipoprotein LpqB, beta-propeller domain, C-terminal MB46_02725 ef10e98c6db4bcc1adc49416a3d3e1ab 235 SUPERFAMILY SSF51569 14 227 1.99E-78 T 14-10-2018 MB46_02725 ef10e98c6db4bcc1adc49416a3d3e1ab 235 TIGRFAM TIGR00126 deoC: deoxyribose-phosphate aldolase 16 226 2.0E-80 T 14-10-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 MB46_02725 ef10e98c6db4bcc1adc49416a3d3e1ab 235 Gene3D G3DSA:3.20.20.70 1 232 1.4E-91 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MB46_02725 ef10e98c6db4bcc1adc49416a3d3e1ab 235 Pfam PF01791 DeoC/LacD family aldolase 22 222 1.6E-19 T 14-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 MB46_02725 ef10e98c6db4bcc1adc49416a3d3e1ab 235 SMART SM01133 15 228 1.9E-94 T 14-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 MB46_02725 ef10e98c6db4bcc1adc49416a3d3e1ab 235 Hamap MF_00114 Deoxyribose-phosphate aldolase [deoC]. 14 230 35.201 T 14-10-2018 IPR028581 Deoxyribose-phosphate aldolase type I GO:0004139 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180 MB46_02725 ef10e98c6db4bcc1adc49416a3d3e1ab 235 PIRSF PIRSF001357 10 233 1.4E-73 T 14-10-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 MB46_05070 f951e8d69dcf1bd59161720d393de0d5 271 Pfam PF00121 Triosephosphate isomerase 14 261 7.6E-82 T 14-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MB46_05070 f951e8d69dcf1bd59161720d393de0d5 271 SUPERFAMILY SSF51351 11 264 3.01E-83 T 14-10-2018 IPR035990 Triosephosphate isomerase superfamily GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MB46_05070 f951e8d69dcf1bd59161720d393de0d5 271 ProSitePatterns PS00171 Triosephosphate isomerase active site. 180 190 - T 14-10-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MB46_05070 f951e8d69dcf1bd59161720d393de0d5 271 Gene3D G3DSA:3.20.20.70 9 270 1.0E-95 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MB46_05070 f951e8d69dcf1bd59161720d393de0d5 271 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 14 255 4.9E-50 T 14-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MB46_05070 f951e8d69dcf1bd59161720d393de0d5 271 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 11 264 56.229 T 14-10-2018 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MB46_03065 753f197203899fe47048d0598fdbfb56 339 Gene3D G3DSA:1.10.3720.10 86 332 2.1E-54 T 14-10-2018 IPR035906 MetI-like superfamily MB46_03065 753f197203899fe47048d0598fdbfb56 339 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 132 294 2.3E-13 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_03065 753f197203899fe47048d0598fdbfb56 339 SUPERFAMILY SSF161098 90 317 2.49E-46 T 14-10-2018 IPR035906 MetI-like superfamily MB46_04565 392e9c1eb2226d42e96772a01457af88 158 Pfam PF12836 Helix-hairpin-helix motif 95 154 5.8E-21 T 14-10-2018 MB46_04565 392e9c1eb2226d42e96772a01457af88 158 Pfam PF10531 SLBB domain 15 69 5.3E-13 T 14-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MB46_04565 392e9c1eb2226d42e96772a01457af88 158 Gene3D G3DSA:1.10.150.280 90 158 2.9E-21 T 14-10-2018 MB46_04565 392e9c1eb2226d42e96772a01457af88 158 Gene3D G3DSA:3.10.560.10 6 82 1.2E-8 T 14-10-2018 MB46_04565 392e9c1eb2226d42e96772a01457af88 158 SUPERFAMILY SSF47781 83 158 2.22E-27 T 14-10-2018 IPR010994 RuvA domain 2-like MB46_10745 4ca61079747134803c8ec288224cda53 101 Gene3D G3DSA:3.30.1390.10 3 97 7.2E-17 T 14-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like MB46_10745 4ca61079747134803c8ec288224cda53 101 Pfam PF02617 ATP-dependent Clp protease adaptor protein ClpS 24 92 8.8E-19 T 14-10-2018 IPR003769 Adaptor protein ClpS, core GO:0030163 Reactome: R-HSA-983168 MB46_10745 4ca61079747134803c8ec288224cda53 101 SUPERFAMILY SSF54736 21 95 4.55E-22 T 14-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like MB46_10745 4ca61079747134803c8ec288224cda53 101 Hamap MF_00302 ATP-dependent Clp protease adapter protein ClpS [clpS]. 5 98 15.266 T 14-10-2018 IPR022935 ATP-dependent Clp protease adaptor protein ClpS MB46_18835 65fcba76aaaa25ef0aab3da69e5f642a 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 73 84 1.5E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_18835 65fcba76aaaa25ef0aab3da69e5f642a 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 126 134 1.5E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_18835 65fcba76aaaa25ef0aab3da69e5f642a 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 146 165 1.5E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_18835 65fcba76aaaa25ef0aab3da69e5f642a 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 3.7E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_18835 65fcba76aaaa25ef0aab3da69e5f642a 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 206 226 3.7E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_18835 65fcba76aaaa25ef0aab3da69e5f642a 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 73 84 3.7E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_18835 65fcba76aaaa25ef0aab3da69e5f642a 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 146 165 3.7E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_18835 65fcba76aaaa25ef0aab3da69e5f642a 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 120 136 3.7E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_18835 65fcba76aaaa25ef0aab3da69e5f642a 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 184 3.7E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_18835 65fcba76aaaa25ef0aab3da69e5f642a 252 Gene3D G3DSA:3.40.50.720 2 247 3.2E-72 T 14-10-2018 MB46_18835 65fcba76aaaa25ef0aab3da69e5f642a 252 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 133 161 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MB46_18835 65fcba76aaaa25ef0aab3da69e5f642a 252 SUPERFAMILY SSF51735 9 244 2.36E-71 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_18835 65fcba76aaaa25ef0aab3da69e5f642a 252 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 242 2.0E-56 T 14-10-2018 MB46_17745 b4f939ea9f10a0c6f973ade926b97e37 85 SUPERFAMILY SSF52833 3 81 4.08E-16 T 14-10-2018 IPR036249 Thioredoxin-like superfamily MB46_17745 b4f939ea9f10a0c6f973ade926b97e37 85 Gene3D G3DSA:3.40.30.10 3 79 8.6E-21 T 14-10-2018 MB46_17745 b4f939ea9f10a0c6f973ade926b97e37 85 Pfam PF05768 Glutaredoxin-like domain (DUF836) 6 75 4.9E-15 T 14-10-2018 IPR008554 Glutaredoxin-like MB46_16205 b75d7d4fc6c990c133f5d61ce85d1a03 627 Gene3D G3DSA:1.10.510.10 101 288 9.8E-50 T 14-10-2018 MB46_16205 b75d7d4fc6c990c133f5d61ce85d1a03 627 SUPERFAMILY SSF56112 4 279 4.26E-74 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily MB46_16205 b75d7d4fc6c990c133f5d61ce85d1a03 627 SMART SM00740 454 522 3.0E-4 T 14-10-2018 IPR005543 PASTA domain MB46_16205 b75d7d4fc6c990c133f5d61ce85d1a03 627 SMART SM00740 536 595 0.4 T 14-10-2018 IPR005543 PASTA domain MB46_16205 b75d7d4fc6c990c133f5d61ce85d1a03 627 SMART SM00740 388 453 7.8E-9 T 14-10-2018 IPR005543 PASTA domain MB46_16205 b75d7d4fc6c990c133f5d61ce85d1a03 627 Pfam PF03793 PASTA domain 461 522 9.9E-7 T 14-10-2018 IPR005543 PASTA domain MB46_16205 b75d7d4fc6c990c133f5d61ce85d1a03 627 Pfam PF03793 PASTA domain 394 453 2.0E-10 T 14-10-2018 IPR005543 PASTA domain MB46_16205 b75d7d4fc6c990c133f5d61ce85d1a03 627 SMART SM00220 11 282 6.6E-63 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 MB46_16205 b75d7d4fc6c990c133f5d61ce85d1a03 627 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 138 150 - T 14-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 MB46_16205 b75d7d4fc6c990c133f5d61ce85d1a03 627 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 17 40 - T 14-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 MB46_16205 b75d7d4fc6c990c133f5d61ce85d1a03 627 Pfam PF00069 Protein kinase domain 11 273 3.5E-51 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 MB46_16205 b75d7d4fc6c990c133f5d61ce85d1a03 627 Gene3D G3DSA:3.30.10.20 389 454 3.1E-13 T 14-10-2018 MB46_16205 b75d7d4fc6c990c133f5d61ce85d1a03 627 Gene3D G3DSA:3.30.10.20 456 524 8.5E-10 T 14-10-2018 MB46_16205 b75d7d4fc6c990c133f5d61ce85d1a03 627 Gene3D G3DSA:3.30.200.20 1 99 1.1E-34 T 14-10-2018 MB46_05265 394df6602d183aedd78289443e858c6a 156 Gene3D G3DSA:3.40.630.30 1 149 4.2E-30 T 14-10-2018 MB46_05265 394df6602d183aedd78289443e858c6a 156 SUPERFAMILY SSF55729 1 138 4.9E-20 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase MB46_05265 394df6602d183aedd78289443e858c6a 156 Pfam PF00583 Acetyltransferase (GNAT) family 44 132 4.7E-11 T 14-10-2018 IPR000182 GNAT domain MB46_01455 17824283d31a4147804686a3a37076b1 1069 Gene3D G3DSA:2.60.120.260 151 275 5.8E-13 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily MB46_01455 17824283d31a4147804686a3a37076b1 1069 Gene3D G3DSA:2.70.98.50 425 598 7.6E-174 T 14-10-2018 MB46_01455 17824283d31a4147804686a3a37076b1 1069 Gene3D G3DSA:2.70.98.50 46 143 1.1E-17 T 14-10-2018 MB46_01455 17824283d31a4147804686a3a37076b1 1069 Gene3D G3DSA:1.50.10.10 608 1033 7.6E-174 T 14-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 MB46_01455 17824283d31a4147804686a3a37076b1 1069 SUPERFAMILY SSF48208 564 1036 5.55E-75 T 14-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 MB46_01455 17824283d31a4147804686a3a37076b1 1069 Pfam PF00754 F5/8 type C domain 155 249 6.6E-8 T 14-10-2018 IPR000421 Coagulation factor 5/8 C-terminal domain MB46_01455 17824283d31a4147804686a3a37076b1 1069 Pfam PF00754 F5/8 type C domain 299 391 6.8E-8 T 14-10-2018 IPR000421 Coagulation factor 5/8 C-terminal domain MB46_01455 17824283d31a4147804686a3a37076b1 1069 SUPERFAMILY SSF49785 155 256 1.35E-11 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily MB46_01455 17824283d31a4147804686a3a37076b1 1069 Pfam PF14498 Glycosyl hydrolase family 65, N-terminal domain 55 105 3.1E-18 T 14-10-2018 IPR027414 Glycosyl hydrolase family 95, N-terminal domain KEGG: 00511+3.2.1.51|MetaCyc: PWY-6807 MB46_01455 17824283d31a4147804686a3a37076b1 1069 Pfam PF14498 Glycosyl hydrolase family 65, N-terminal domain 407 553 1.8E-22 T 14-10-2018 IPR027414 Glycosyl hydrolase family 95, N-terminal domain KEGG: 00511+3.2.1.51|MetaCyc: PWY-6807 MB46_01455 17824283d31a4147804686a3a37076b1 1069 SUPERFAMILY SSF49785 284 418 4.89E-10 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily MB46_01455 17824283d31a4147804686a3a37076b1 1069 Gene3D G3DSA:2.60.40.1180 599 1048 7.6E-174 T 14-10-2018 IPR013780 Glycosyl hydrolase, all-beta MB46_03950 7327d604ead1495ef6923d96bf6e9f69 675 Gene3D G3DSA:3.40.50.300 24 307 8.3E-40 T 14-10-2018 MB46_03950 7327d604ead1495ef6923d96bf6e9f69 675 SMART SM00491 513 642 2.0E-39 T 14-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 MB46_03950 7327d604ead1495ef6923d96bf6e9f69 675 Gene3D G3DSA:3.40.50.300 480 670 1.0E-32 T 14-10-2018 MB46_03950 7327d604ead1495ef6923d96bf6e9f69 675 Pfam PF00270 DEAD/DEAH box helicase 35 89 3.1E-6 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MB46_03950 7327d604ead1495ef6923d96bf6e9f69 675 SMART SM00487 21 331 0.0014 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MB46_03950 7327d604ead1495ef6923d96bf6e9f69 675 Pfam PF13307 Helicase C-terminal domain 496 655 1.6E-32 T 14-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 MB46_03950 7327d604ead1495ef6923d96bf6e9f69 675 SUPERFAMILY SSF52540 37 635 3.77E-23 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_08305 6ab8e77e0d2bf201881437e352e9754b 375 SUPERFAMILY SSF48576 22 374 1.06E-68 T 14-10-2018 IPR008949 Isoprenoid synthase domain superfamily MB46_08305 6ab8e77e0d2bf201881437e352e9754b 375 Gene3D G3DSA:1.10.600.10 5 375 9.2E-104 T 14-10-2018 IPR008949 Isoprenoid synthase domain superfamily MB46_08305 6ab8e77e0d2bf201881437e352e9754b 375 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 98 112 - T 14-10-2018 IPR033749 Polyprenyl synthetase, conserved site MB46_08305 6ab8e77e0d2bf201881437e352e9754b 375 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 253 265 - T 14-10-2018 IPR033749 Polyprenyl synthetase, conserved site MB46_08305 6ab8e77e0d2bf201881437e352e9754b 375 Pfam PF00348 Polyprenyl synthetase 49 325 2.6E-51 T 14-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 MB46_04100 f33c60382df1761d298004844d306fe9 234 SUPERFAMILY SSF56214 127 230 8.11E-12 T 14-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 MB46_04100 f33c60382df1761d298004844d306fe9 234 Gene3D G3DSA:3.90.470.20 25 141 1.0E-12 T 14-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 MB46_04100 f33c60382df1761d298004844d306fe9 234 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 127 199 2.6E-7 T 14-10-2018 IPR008278 4'-phosphopantetheinyl transferase domain GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 MB46_04100 f33c60382df1761d298004844d306fe9 234 SUPERFAMILY SSF56214 28 117 1.44E-6 T 14-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 MB46_02410 f7205e3fd2c9a8c95544f314365d2bd7 297 SUPERFAMILY SSF51556 38 293 3.19E-66 T 14-10-2018 IPR032466 Metal-dependent hydrolase MB46_02410 f7205e3fd2c9a8c95544f314365d2bd7 297 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 38 292 1.7E-63 T 14-10-2018 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 MB46_02410 f7205e3fd2c9a8c95544f314365d2bd7 297 Gene3D G3DSA:3.20.20.140 33 294 1.6E-66 T 14-10-2018 MB46_02410 f7205e3fd2c9a8c95544f314365d2bd7 297 PIRSF PIRSF005902 4 297 8.1E-66 T 14-10-2018 IPR001130 TatD family GO:0016788 MB46_02410 f7205e3fd2c9a8c95544f314365d2bd7 297 Pfam PF01026 TatD related DNase 39 292 2.3E-58 T 14-10-2018 IPR001130 TatD family GO:0016788 MB46_18305 f8681323a870ed1dc5d092aa19841cd2 923 Gene3D G3DSA:3.40.50.300 585 769 1.6E-38 T 14-10-2018 MB46_18305 f8681323a870ed1dc5d092aa19841cd2 923 Pfam PF13087 AAA domain 575 740 2.8E-27 T 14-10-2018 MB46_18305 f8681323a870ed1dc5d092aa19841cd2 923 SUPERFAMILY SSF52540 187 759 9.39E-50 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_18305 f8681323a870ed1dc5d092aa19841cd2 923 Pfam PF13086 AAA domain 190 537 4.9E-21 T 14-10-2018 MB46_18305 f8681323a870ed1dc5d092aa19841cd2 923 Pfam PF10881 Protein of unknown function (DUF2726) 800 919 3.6E-11 T 14-10-2018 IPR024402 Domain of unknown function DUF2726 MB46_04000 1f5d1481496430086b99352df5669e8e 355 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 1 154 8.8E-54 T 14-10-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 MB46_04000 1f5d1481496430086b99352df5669e8e 355 Gene3D G3DSA:3.30.110.10 61 156 1.0E-32 T 14-10-2018 IPR036788 Translation initiation factor 3 (IF-3), C-terminal domain superfamily GO:0006413 Reactome: R-HSA-5368286 MB46_04000 1f5d1481496430086b99352df5669e8e 355 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 1 61 6.9E-24 T 14-10-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 MB46_04000 1f5d1481496430086b99352df5669e8e 355 Gene3D G3DSA:3.10.20.80 1 60 1.3E-24 T 14-10-2018 IPR036787 Translation initiation factor 3 (IF-3), N-terminal domain superfamily GO:0003743|GO:0006413 Reactome: R-HSA-5368286 MB46_04000 1f5d1481496430086b99352df5669e8e 355 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 1 155 24.152 T 14-10-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 MB46_04000 1f5d1481496430086b99352df5669e8e 355 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 69 152 2.7E-31 T 14-10-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 MB46_04000 1f5d1481496430086b99352df5669e8e 355 SUPERFAMILY SSF55200 68 156 1.1E-28 T 14-10-2018 IPR036788 Translation initiation factor 3 (IF-3), C-terminal domain superfamily GO:0006413 Reactome: R-HSA-5368286 MB46_04000 1f5d1481496430086b99352df5669e8e 355 SUPERFAMILY SSF54364 1 63 3.01E-22 T 14-10-2018 IPR036787 Translation initiation factor 3 (IF-3), N-terminal domain superfamily GO:0003743|GO:0006413 Reactome: R-HSA-5368286 MB46_13600 5691335d9a2d7653088fd7b8b6643e20 232 SUPERFAMILY SSF46894 123 220 2.17E-31 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MB46_13600 5691335d9a2d7653088fd7b8b6643e20 232 Gene3D G3DSA:1.10.10.10 119 228 1.2E-36 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_13600 5691335d9a2d7653088fd7b8b6643e20 232 SMART SM00862 145 219 2.0E-29 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MB46_13600 5691335d9a2d7653088fd7b8b6643e20 232 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 219 4.8E-29 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MB46_13600 5691335d9a2d7653088fd7b8b6643e20 232 Gene3D G3DSA:3.40.50.2300 1 118 4.0E-40 T 14-10-2018 MB46_10040 5f525a0e8c959b712c0d328a1af8c800 370 SUPERFAMILY SSF56752 7 366 1.83E-110 T 14-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 MB46_10040 5f525a0e8c959b712c0d328a1af8c800 370 ProSitePatterns PS00770 Aminotransferases class-IV signature. 245 275 - T 14-10-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824 Reactome: R-HSA-70895 MB46_10040 5f525a0e8c959b712c0d328a1af8c800 370 Gene3D G3DSA:3.20.10.10 183 352 4.4E-129 T 14-10-2018 MB46_10040 5f525a0e8c959b712c0d328a1af8c800 370 Gene3D G3DSA:3.30.470.10 33 365 4.4E-129 T 14-10-2018 MB46_10040 5f525a0e8c959b712c0d328a1af8c800 370 PIRSF PIRSF006468 7 370 1.5E-127 T 14-10-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 MB46_10040 5f525a0e8c959b712c0d328a1af8c800 370 TIGRFAM TIGR01123 ilvE_II: branched-chain amino acid aminotransferase 56 368 3.2E-132 T 14-10-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 MB46_10040 5f525a0e8c959b712c0d328a1af8c800 370 Pfam PF01063 Amino-transferase class IV 82 325 4.4E-38 T 14-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 MB46_11085 d18b6af9bcea349ebc851c720ad650ba 306 Gene3D G3DSA:3.40.50.1980 38 183 3.4E-29 T 14-10-2018 MB46_11085 d18b6af9bcea349ebc851c720ad650ba 306 SUPERFAMILY SSF53807 35 301 3.29E-50 T 14-10-2018 MB46_11085 d18b6af9bcea349ebc851c720ad650ba 306 Pfam PF01297 Zinc-uptake complex component A periplasmic 40 298 5.8E-38 T 14-10-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 MB46_19275 0d9955f65081c2bae83ff6d7183358ae 185 Pfam PF00436 Single-strand binding protein family 6 106 7.7E-31 T 14-10-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 MB46_19275 0d9955f65081c2bae83ff6d7183358ae 185 SUPERFAMILY SSF50249 6 185 3.92E-47 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold MB46_19275 0d9955f65081c2bae83ff6d7183358ae 185 Gene3D G3DSA:2.40.50.140 1 120 4.9E-43 T 14-10-2018 MB46_19275 0d9955f65081c2bae83ff6d7183358ae 185 Hamap MF_00984 Single-stranded DNA-binding protein. 4 113 31.771 T 14-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 MB46_19275 0d9955f65081c2bae83ff6d7183358ae 185 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 5 134 5.8E-33 T 14-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 MB46_05320 43f7f093973949a8c71734bd650d9fe8 458 Gene3D G3DSA:3.40.50.720 36 212 1.2E-41 T 14-10-2018 MB46_05320 43f7f093973949a8c71734bd650d9fe8 458 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 219 395 1.2E-5 T 14-10-2018 MB46_05320 43f7f093973949a8c71734bd650d9fe8 458 SUPERFAMILY SSF51735 214 454 7.27E-59 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_05320 43f7f093973949a8c71734bd650d9fe8 458 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 364 383 5.6E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_05320 43f7f093973949a8c71734bd650d9fe8 458 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 291 302 5.6E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_05320 43f7f093973949a8c71734bd650d9fe8 458 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 344 352 5.6E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_05320 43f7f093973949a8c71734bd650d9fe8 458 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 351 379 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MB46_05320 43f7f093973949a8c71734bd650d9fe8 458 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 291 302 1.2E-31 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_05320 43f7f093973949a8c71734bd650d9fe8 458 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 418 438 1.2E-31 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_05320 43f7f093973949a8c71734bd650d9fe8 458 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 220 237 1.2E-31 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_05320 43f7f093973949a8c71734bd650d9fe8 458 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 364 383 1.2E-31 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_05320 43f7f093973949a8c71734bd650d9fe8 458 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 385 402 1.2E-31 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_05320 43f7f093973949a8c71734bd650d9fe8 458 Gene3D G3DSA:3.40.50.720 213 457 3.5E-66 T 14-10-2018 MB46_05320 43f7f093973949a8c71734bd650d9fe8 458 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 225 451 3.8E-50 T 14-10-2018 MB46_16425 2b1c0824a073ba7b91b37daf91175ad0 240 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 59 3.9E-12 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MB46_16425 2b1c0824a073ba7b91b37daf91175ad0 240 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 57 3.5E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MB46_16425 2b1c0824a073ba7b91b37daf91175ad0 240 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 13 26 3.5E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MB46_16425 2b1c0824a073ba7b91b37daf91175ad0 240 SUPERFAMILY SSF48498 80 163 5.48E-6 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily MB46_16425 2b1c0824a073ba7b91b37daf91175ad0 240 Pfam PF13305 WHG domain 86 163 4.0E-7 T 14-10-2018 IPR025996 WHG domain MB46_16425 2b1c0824a073ba7b91b37daf91175ad0 240 SUPERFAMILY SSF46689 10 80 1.4E-13 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MB46_16425 2b1c0824a073ba7b91b37daf91175ad0 240 Gene3D G3DSA:1.10.357.10 5 188 2.7E-26 T 14-10-2018 MB46_04655 8f717ada35a7ff7dacb4948469d8e43f 668 Pfam PF05649 Peptidase family M13 31 410 1.1E-91 T 14-10-2018 IPR008753 Peptidase M13, N-terminal domain GO:0006508 MB46_04655 8f717ada35a7ff7dacb4948469d8e43f 668 SUPERFAMILY SSF55486 15 668 2.56E-199 T 14-10-2018 MB46_04655 8f717ada35a7ff7dacb4948469d8e43f 668 Pfam PF01431 Peptidase family M13 462 664 2.6E-70 T 14-10-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 MB46_04655 8f717ada35a7ff7dacb4948469d8e43f 668 Gene3D G3DSA:1.10.1380.10 57 449 1.3E-231 T 14-10-2018 MB46_04655 8f717ada35a7ff7dacb4948469d8e43f 668 Gene3D G3DSA:3.40.390.10 26 668 1.3E-231 T 14-10-2018 IPR024079 Metallopeptidase, catalytic domain superfamily GO:0008237 MB46_04655 8f717ada35a7ff7dacb4948469d8e43f 668 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 566 577 4.4E-22 T 14-10-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 MB46_04655 8f717ada35a7ff7dacb4948469d8e43f 668 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 454 466 4.4E-22 T 14-10-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 MB46_04655 8f717ada35a7ff7dacb4948469d8e43f 668 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 493 509 4.4E-22 T 14-10-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 MB46_04655 8f717ada35a7ff7dacb4948469d8e43f 668 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 472 484 4.4E-22 T 14-10-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 MB46_15985 056a6dbb144a692d366a89bb9d5392eb 430 PIRSF PIRSF037434 2 424 2.4E-122 T 14-10-2018 IPR017205 Signal transduction histidine kinase, ChrS MB46_15985 056a6dbb144a692d366a89bb9d5392eb 430 SMART SM00387 318 419 5.0E-4 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MB46_15985 056a6dbb144a692d366a89bb9d5392eb 430 Gene3D G3DSA:3.30.565.10 279 418 4.1E-27 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MB46_15985 056a6dbb144a692d366a89bb9d5392eb 430 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 337 418 1.2E-7 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MB46_15985 056a6dbb144a692d366a89bb9d5392eb 430 PRINTS PR00344 Bacterial sensor protein C-terminal signature 403 416 7.4E-9 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MB46_15985 056a6dbb144a692d366a89bb9d5392eb 430 PRINTS PR00344 Bacterial sensor protein C-terminal signature 354 368 7.4E-9 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MB46_15985 056a6dbb144a692d366a89bb9d5392eb 430 PRINTS PR00344 Bacterial sensor protein C-terminal signature 379 397 7.4E-9 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MB46_15985 056a6dbb144a692d366a89bb9d5392eb 430 Pfam PF07730 Histidine kinase 207 274 7.1E-15 T 14-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 MB46_15985 056a6dbb144a692d366a89bb9d5392eb 430 SUPERFAMILY SSF55874 296 417 1.15E-19 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MB46_15980 1435e5e36e01d79ba90a64e8531f46d4 216 SUPERFAMILY SSF46894 140 212 5.44E-21 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MB46_15980 1435e5e36e01d79ba90a64e8531f46d4 216 SMART SM00421 149 206 3.1E-22 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_15980 1435e5e36e01d79ba90a64e8531f46d4 216 Pfam PF00072 Response regulator receiver domain 6 124 5.0E-26 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MB46_15980 1435e5e36e01d79ba90a64e8531f46d4 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 182 194 6.6E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_15980 1435e5e36e01d79ba90a64e8531f46d4 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 152 166 6.6E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_15980 1435e5e36e01d79ba90a64e8531f46d4 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 166 182 6.6E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_15980 1435e5e36e01d79ba90a64e8531f46d4 216 SUPERFAMILY SSF52172 1 141 9.82E-31 T 14-10-2018 IPR011006 CheY-like superfamily MB46_15980 1435e5e36e01d79ba90a64e8531f46d4 216 Gene3D G3DSA:3.40.50.12740 4 212 3.3E-63 T 14-10-2018 MB46_15980 1435e5e36e01d79ba90a64e8531f46d4 216 Pfam PF00196 Bacterial regulatory proteins, luxR family 151 206 4.0E-20 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_15980 1435e5e36e01d79ba90a64e8531f46d4 216 ProSitePatterns PS00622 LuxR-type HTH domain signature. 166 193 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_15980 1435e5e36e01d79ba90a64e8531f46d4 216 SMART SM00448 4 123 8.2E-32 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MB46_10615 d7b66dc4e5c8d02407dd87cad0ee0cff 316 Gene3D G3DSA:3.40.50.1980 153 315 3.4E-24 T 14-10-2018 MB46_10615 d7b66dc4e5c8d02407dd87cad0ee0cff 316 SUPERFAMILY SSF53807 49 306 5.49E-51 T 14-10-2018 MB46_10615 d7b66dc4e5c8d02407dd87cad0ee0cff 316 Pfam PF01497 Periplasmic binding protein 65 269 4.4E-26 T 14-10-2018 IPR002491 ABC transporter periplasmic binding domain MB46_10615 d7b66dc4e5c8d02407dd87cad0ee0cff 316 Gene3D G3DSA:3.40.50.1980 41 150 3.4E-31 T 14-10-2018 MB46_19360 3d92f138e52fea9eff3af9451f83e014 140 SUPERFAMILY SSF54593 1 130 8.8E-18 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MB46_19360 3d92f138e52fea9eff3af9451f83e014 140 Gene3D G3DSA:3.10.180.10 1 138 1.7E-25 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MB46_10905 c4576242b655a24b907efb60206ee285 332 Pfam PF01370 NAD dependent epimerase/dehydratase family 10 194 2.6E-17 T 14-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 MB46_10905 c4576242b655a24b907efb60206ee285 332 SUPERFAMILY SSF51735 9 260 1.13E-24 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_10905 c4576242b655a24b907efb60206ee285 332 Gene3D G3DSA:3.40.50.720 2 269 1.4E-24 T 14-10-2018 MB46_08075 664e3837ab12f4311a592e33b30dcc0a 227 TIGRFAM TIGR00214 lipB: lipoyl(octanoyl) transferase 38 189 3.8E-36 T 14-10-2018 IPR000544 Octanoyltransferase GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 MB46_08075 664e3837ab12f4311a592e33b30dcc0a 227 Hamap MF_00013 Octanoyltransferase [lipB]. 2 213 31.161 T 14-10-2018 IPR000544 Octanoyltransferase GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 MB46_08075 664e3837ab12f4311a592e33b30dcc0a 227 SUPERFAMILY SSF55681 11 210 9.94E-58 T 14-10-2018 MB46_08075 664e3837ab12f4311a592e33b30dcc0a 227 PIRSF PIRSF016262 3 222 3.5E-58 T 14-10-2018 IPR000544 Octanoyltransferase GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 MB46_08075 664e3837ab12f4311a592e33b30dcc0a 227 ProSitePatterns PS01313 Lipoate-protein ligase B signature. 72 87 - T 14-10-2018 IPR020605 Octanoyltransferase, conserved site GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 MB46_08075 664e3837ab12f4311a592e33b30dcc0a 227 Pfam PF03099 Biotin/lipoate A/B protein ligase family 63 163 8.7E-10 T 14-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 MB46_08075 664e3837ab12f4311a592e33b30dcc0a 227 ProDom PD006086 LIGASE LIPOATE-PROTEIN B TRANSFERASE ACYLTRANSFERASE LIPOYLTRANSFERASE LIPOYL-ACYL-CARRIER 2.3.1.- PROTEIN-PROTEIN- N-LIPOYLTRANSFERASE 77 128 4.0E-11 T 14-10-2018 MB46_08075 664e3837ab12f4311a592e33b30dcc0a 227 Gene3D G3DSA:3.30.930.10 3 210 2.0E-68 T 14-10-2018 MB46_17500 efb3871150a443c0f63231fc7918e6af 169 SUPERFAMILY SSF46767 78 159 5.36E-31 T 14-10-2018 IPR036217 Methylated DNA-protein cysteine methyltransferase, DNA binding domain Reactome: R-HSA-5657655 MB46_17500 efb3871150a443c0f63231fc7918e6af 169 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 129 135 - T 14-10-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 MB46_17500 efb3871150a443c0f63231fc7918e6af 169 SUPERFAMILY SSF53155 3 84 9.42E-18 T 14-10-2018 IPR036631 Methylated DNA-protein cysteine methyltransferase domain superfamily GO:0003908|GO:0006281 Reactome: R-HSA-5657655 MB46_17500 efb3871150a443c0f63231fc7918e6af 169 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 80 158 6.8E-33 T 14-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 MB46_17500 efb3871150a443c0f63231fc7918e6af 169 Gene3D G3DSA:1.10.10.10 77 160 1.6E-35 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_17500 efb3871150a443c0f63231fc7918e6af 169 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 6 159 40.793 T 14-10-2018 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 MB46_17500 efb3871150a443c0f63231fc7918e6af 169 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 80 158 1.3E-32 T 14-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 MB46_17500 efb3871150a443c0f63231fc7918e6af 169 Gene3D G3DSA:3.30.160.70 1 74 1.8E-17 T 14-10-2018 MB46_10010 35e3a6a1d88fc5829290b5f6b25c9dca 399 Gene3D G3DSA:3.30.565.10 248 386 7.4E-21 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MB46_10010 35e3a6a1d88fc5829290b5f6b25c9dca 399 SUPERFAMILY SSF55874 280 381 1.83E-5 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MB46_10010 35e3a6a1d88fc5829290b5f6b25c9dca 399 Pfam PF07730 Histidine kinase 173 236 2.3E-14 T 14-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 MB46_14965 50b2c4ef81537545230043d913c83860 188 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 20 181 3.3E-36 T 14-10-2018 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MB46_14965 50b2c4ef81537545230043d913c83860 188 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 188 24.026 T 14-10-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MB46_14965 50b2c4ef81537545230043d913c83860 188 Gene3D G3DSA:3.40.50.2020 2 188 7.2E-45 T 14-10-2018 MB46_14965 50b2c4ef81537545230043d913c83860 188 Pfam PF00156 Phosphoribosyl transferase domain 98 167 4.8E-8 T 14-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 MB46_14965 50b2c4ef81537545230043d913c83860 188 SUPERFAMILY SSF53271 11 184 1.06E-32 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like MB46_14825 a7a0d24f794eeff798ce8f1093fb16ee 462 SUPERFAMILY SSF52540 213 432 2.26E-30 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_14825 a7a0d24f794eeff798ce8f1093fb16ee 462 SMART SM00382 248 375 4.9E-8 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_14825 a7a0d24f794eeff798ce8f1093fb16ee 462 Gene3D G3DSA:3.40.50.300 203 374 2.8E-28 T 14-10-2018 MB46_14825 a7a0d24f794eeff798ce8f1093fb16ee 462 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 252 372 1.4E-16 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MB46_16455 0551edbe9aa67e623b31e0415f593add 439 Gene3D G3DSA:3.40.190.10 40 395 8.5E-138 T 14-10-2018 MB46_16455 0551edbe9aa67e623b31e0415f593add 439 Gene3D G3DSA:3.40.190.10 139 424 8.5E-138 T 14-10-2018 MB46_16455 0551edbe9aa67e623b31e0415f593add 439 SUPERFAMILY SSF53850 12 429 1.76E-74 T 14-10-2018 MB46_16455 0551edbe9aa67e623b31e0415f593add 439 Pfam PF01547 Bacterial extracellular solute-binding protein 38 326 1.5E-46 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein MB46_09920 d4ce29b0f920f15bf8f9e27f12a0224d 345 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 192 330 3.2E-45 T 14-10-2018 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 MB46_09920 d4ce29b0f920f15bf8f9e27f12a0224d 345 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 210 234 1.7E-47 T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 MB46_09920 d4ce29b0f920f15bf8f9e27f12a0224d 345 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 68 95 1.7E-47 T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 MB46_09920 d4ce29b0f920f15bf8f9e27f12a0224d 345 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 250 267 1.7E-47 T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 MB46_09920 d4ce29b0f920f15bf8f9e27f12a0224d 345 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 185 209 1.7E-47 T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 MB46_09920 d4ce29b0f920f15bf8f9e27f12a0224d 345 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 14 31 1.7E-47 T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 MB46_09920 d4ce29b0f920f15bf8f9e27f12a0224d 345 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 145 165 1.7E-47 T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 MB46_09920 d4ce29b0f920f15bf8f9e27f12a0224d 345 Gene3D G3DSA:1.10.1040.10 202 344 2.1E-43 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MB46_09920 d4ce29b0f920f15bf8f9e27f12a0224d 345 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 11 172 2.4E-51 T 14-10-2018 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 MB46_09920 d4ce29b0f920f15bf8f9e27f12a0224d 345 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 10 334 34.819 T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 MB46_09920 d4ce29b0f920f15bf8f9e27f12a0224d 345 Gene3D G3DSA:3.40.50.720 4 199 2.6E-62 T 14-10-2018 MB46_09920 d4ce29b0f920f15bf8f9e27f12a0224d 345 PIRSF PIRSF000114 5 344 5.1E-99 T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 MB46_09920 d4ce29b0f920f15bf8f9e27f12a0224d 345 SUPERFAMILY SSF48179 191 343 1.19E-49 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MB46_09920 d4ce29b0f920f15bf8f9e27f12a0224d 345 SUPERFAMILY SSF51735 10 192 9.24E-49 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_09920 d4ce29b0f920f15bf8f9e27f12a0224d 345 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 200 221 - T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 MB46_04290 b9d9b85713c045b2569de87d7523cbab 134 Gene3D G3DSA:3.30.1330.40 1 133 1.6E-36 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 MB46_04290 b9d9b85713c045b2569de87d7523cbab 134 SUPERFAMILY SSF55298 4 133 5.81E-33 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 MB46_04290 b9d9b85713c045b2569de87d7523cbab 134 Pfam PF01042 Endoribonuclease L-PSP 9 132 1.9E-27 T 14-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 MB46_03135 b677962284ee4feb514e7fc1184b8151 292 SUPERFAMILY SSF53067 14 289 3.47E-39 T 14-10-2018 MB46_03135 b677962284ee4feb514e7fc1184b8151 292 Gene3D G3DSA:3.30.420.40 118 274 1.8E-55 T 14-10-2018 MB46_03135 b677962284ee4feb514e7fc1184b8151 292 Gene3D G3DSA:3.30.420.40 13 281 1.8E-55 T 14-10-2018 MB46_03135 b677962284ee4feb514e7fc1184b8151 292 Pfam PF00480 ROK family 16 282 1.5E-35 T 14-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 MB46_09180 f742028e73dfc6fd8639e4681c44c1ca 331 Gene3D G3DSA:3.40.50.720 123 299 2.6E-101 T 14-10-2018 MB46_09180 f742028e73dfc6fd8639e4681c44c1ca 331 SUPERFAMILY SSF50129 1 148 1.26E-36 T 14-10-2018 IPR011032 GroES-like superfamily MB46_09180 f742028e73dfc6fd8639e4681c44c1ca 331 Gene3D G3DSA:3.90.180.10 14 328 2.6E-101 T 14-10-2018 MB46_09180 f742028e73dfc6fd8639e4681c44c1ca 331 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 89 9.6E-11 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MB46_09180 f742028e73dfc6fd8639e4681c44c1ca 331 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 143 164 - T 14-10-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 MB46_09180 f742028e73dfc6fd8639e4681c44c1ca 331 SUPERFAMILY SSF51735 115 295 2.84E-41 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_09180 f742028e73dfc6fd8639e4681c44c1ca 331 Pfam PF13602 Zinc-binding dehydrogenase 185 328 2.6E-32 T 14-10-2018 MB46_09180 f742028e73dfc6fd8639e4681c44c1ca 331 SMART SM00829 10 328 2.9E-43 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MB46_00220 1b94b54873ecf100267fc8b3fa3b5d2f 556 SUPERFAMILY SSF53850 30 552 6.79E-70 T 14-10-2018 MB46_00220 1b94b54873ecf100267fc8b3fa3b5d2f 556 Pfam PF13416 Bacterial extracellular solute-binding protein 84 399 5.6E-20 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein MB46_00220 1b94b54873ecf100267fc8b3fa3b5d2f 556 Gene3D G3DSA:3.40.190.10 185 551 3.3E-86 T 14-10-2018 MB46_00220 1b94b54873ecf100267fc8b3fa3b5d2f 556 Gene3D G3DSA:3.40.190.10 86 463 3.3E-86 T 14-10-2018 MB46_11800 c0a8030aeb1851b682c2d0c2b32f3bc9 556 SUPERFAMILY SSF50156 447 552 9.99E-20 T 14-10-2018 IPR036034 PDZ superfamily GO:0005515 MB46_11800 c0a8030aeb1851b682c2d0c2b32f3bc9 556 Pfam PF13180 PDZ domain 464 552 1.7E-17 T 14-10-2018 IPR001478 PDZ domain GO:0005515 MB46_11800 c0a8030aeb1851b682c2d0c2b32f3bc9 556 Gene3D G3DSA:2.30.42.10 462 556 1.4E-24 T 14-10-2018 MB46_11800 c0a8030aeb1851b682c2d0c2b32f3bc9 556 Gene3D G3DSA:2.40.10.10 305 461 2.2E-41 T 14-10-2018 MB46_11800 c0a8030aeb1851b682c2d0c2b32f3bc9 556 Gene3D G3DSA:2.40.10.10 208 304 2.9E-26 T 14-10-2018 MB46_11800 c0a8030aeb1851b682c2d0c2b32f3bc9 556 Pfam PF13365 Trypsin-like peptidase domain 240 417 2.3E-30 T 14-10-2018 MB46_11800 c0a8030aeb1851b682c2d0c2b32f3bc9 556 SUPERFAMILY SSF50494 214 459 4.18E-51 T 14-10-2018 IPR009003 Peptidase S1, PA clan MB46_11800 c0a8030aeb1851b682c2d0c2b32f3bc9 556 PRINTS PR00834 HtrA/DegQ protease family signature 501 513 9.9E-30 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MB46_11800 c0a8030aeb1851b682c2d0c2b32f3bc9 556 PRINTS PR00834 HtrA/DegQ protease family signature 410 427 9.9E-30 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MB46_11800 c0a8030aeb1851b682c2d0c2b32f3bc9 556 PRINTS PR00834 HtrA/DegQ protease family signature 249 261 9.9E-30 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MB46_11800 c0a8030aeb1851b682c2d0c2b32f3bc9 556 PRINTS PR00834 HtrA/DegQ protease family signature 275 295 9.9E-30 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MB46_11800 c0a8030aeb1851b682c2d0c2b32f3bc9 556 PRINTS PR00834 HtrA/DegQ protease family signature 388 405 9.9E-30 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MB46_11800 c0a8030aeb1851b682c2d0c2b32f3bc9 556 SMART SM00228 464 543 1.7E-11 T 14-10-2018 IPR001478 PDZ domain GO:0005515 MB46_04140 897e9bb0483d1a5993ffcd3736ae256f 389 Gene3D G3DSA:3.10.20.340 264 389 6.5E-38 T 14-10-2018 MB46_04140 897e9bb0483d1a5993ffcd3736ae256f 389 ProDom PD004193 ACETYLTRANSFERASE ORNITHINE ARGININE BIOSYNTHESIS ARGJ GLUTAMATE N-ACETYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIFUNCTIONAL 17 387 1.0E-155 T 14-10-2018 MB46_04140 897e9bb0483d1a5993ffcd3736ae256f 389 TIGRFAM TIGR00120 ArgJ: glutamate N-acetyltransferase/amino-acid acetyltransferase 2 388 5.4E-106 T 14-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 MB46_04140 897e9bb0483d1a5993ffcd3736ae256f 389 Hamap MF_01106 Arginine biosynthesis bifunctional protein ArgJ [argJ]. 1 389 135.026 T 14-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 MB46_04140 897e9bb0483d1a5993ffcd3736ae256f 389 SUPERFAMILY SSF56266 6 385 1.16E-125 T 14-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 MB46_04140 897e9bb0483d1a5993ffcd3736ae256f 389 Pfam PF01960 ArgJ family 11 389 3.7E-130 T 14-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 MB46_04140 897e9bb0483d1a5993ffcd3736ae256f 389 Gene3D G3DSA:3.60.70.12 1 184 1.2E-63 T 14-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 MB46_04140 897e9bb0483d1a5993ffcd3736ae256f 389 Gene3D G3DSA:3.30.2330.10 185 263 1.2E-24 T 14-10-2018 MB46_16355 5f058944f209ef66ae65faa6e7303df4 323 Pfam PF01380 SIS domain 144 271 4.6E-16 T 14-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 MB46_16355 5f058944f209ef66ae65faa6e7303df4 323 SUPERFAMILY SSF53697 117 277 1.83E-33 T 14-10-2018 MB46_16355 5f058944f209ef66ae65faa6e7303df4 323 Pfam PF01418 Helix-turn-helix domain, rpiR family 15 87 3.5E-14 T 14-10-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 MB46_16355 5f058944f209ef66ae65faa6e7303df4 323 Gene3D G3DSA:3.40.50.10490 111 296 8.7E-37 T 14-10-2018 MB46_16355 5f058944f209ef66ae65faa6e7303df4 323 SUPERFAMILY SSF46689 15 88 9.85E-17 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MB46_16355 5f058944f209ef66ae65faa6e7303df4 323 Gene3D G3DSA:1.10.10.10 10 93 1.0E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_07310 8aaac709424dc8812c1419edf6f64141 243 SUPERFAMILY SSF48371 30 227 2.02E-9 T 14-10-2018 IPR016024 Armadillo-type fold MB46_18320 0b06024998f5bc9d592d434a539587b0 602 Gene3D G3DSA:2.60.40.10 237 334 1.7E-10 T 14-10-2018 IPR013783 Immunoglobulin-like fold MB46_18320 0b06024998f5bc9d592d434a539587b0 602 Gene3D G3DSA:2.60.40.10 47 145 4.3E-13 T 14-10-2018 IPR013783 Immunoglobulin-like fold MB46_18320 0b06024998f5bc9d592d434a539587b0 602 Gene3D G3DSA:2.60.40.10 335 429 2.2E-6 T 14-10-2018 IPR013783 Immunoglobulin-like fold MB46_18320 0b06024998f5bc9d592d434a539587b0 602 Pfam PF13750 Bacterial Ig-like domain (group 3) 293 357 0.0056 T 14-10-2018 IPR022038 Bacterial Ig-like domain MB46_17610 5e7c0e722c23985e28f9e99fae7bd1fb 776 PRINTS PR00742 Glycosyl hydrolase family 35 signature 110 129 5.0E-17 T 14-10-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 MB46_17610 5e7c0e722c23985e28f9e99fae7bd1fb 776 PRINTS PR00742 Glycosyl hydrolase family 35 signature 164 179 5.0E-17 T 14-10-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 MB46_17610 5e7c0e722c23985e28f9e99fae7bd1fb 776 PRINTS PR00742 Glycosyl hydrolase family 35 signature 313 328 5.0E-17 T 14-10-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 MB46_17610 5e7c0e722c23985e28f9e99fae7bd1fb 776 PRINTS PR00742 Glycosyl hydrolase family 35 signature 55 73 5.0E-17 T 14-10-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 MB46_17610 5e7c0e722c23985e28f9e99fae7bd1fb 776 PRINTS PR00742 Glycosyl hydrolase family 35 signature 335 351 5.0E-17 T 14-10-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 MB46_17610 5e7c0e722c23985e28f9e99fae7bd1fb 776 PRINTS PR00742 Glycosyl hydrolase family 35 signature 34 51 5.0E-17 T 14-10-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 MB46_17610 5e7c0e722c23985e28f9e99fae7bd1fb 776 Gene3D G3DSA:3.20.20.80 21 380 7.8E-97 T 14-10-2018 MB46_17610 5e7c0e722c23985e28f9e99fae7bd1fb 776 Gene3D G3DSA:2.102.20.10 395 552 2.2E-5 T 14-10-2018 IPR037110 Beta-galactosidase, domain 2 superfamily KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 MB46_17610 5e7c0e722c23985e28f9e99fae7bd1fb 776 SUPERFAMILY SSF51445 25 370 8.97E-59 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily MB46_17610 5e7c0e722c23985e28f9e99fae7bd1fb 776 Pfam PF01301 Glycosyl hydrolases family 35 31 371 1.3E-51 T 14-10-2018 IPR031330 Glycoside hydrolase 35, catalytic domain KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 MB46_17610 5e7c0e722c23985e28f9e99fae7bd1fb 776 Pfam PF10435 Beta-galactosidase, domain 2 404 511 1.2E-5 T 14-10-2018 IPR018954 Beta-galactosidase, domain 2 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 MB46_01910 40d1dcb624f833cb0aa66d1095c686c5 296 Gene3D G3DSA:3.40.960.10 190 296 1.3E-12 T 14-10-2018 MB46_01910 40d1dcb624f833cb0aa66d1095c686c5 296 SUPERFAMILY SSF52980 180 286 2.9E-7 T 14-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 MB46_01800 d8d65bb9006e9d40e6f63eefd6409e2a 328 Gene3D G3DSA:3.20.20.100 1 325 2.7E-73 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily MB46_01800 d8d65bb9006e9d40e6f63eefd6409e2a 328 SUPERFAMILY SSF51430 1 316 2.49E-71 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily MB46_01800 d8d65bb9006e9d40e6f63eefd6409e2a 328 Pfam PF00248 Aldo/keto reductase family 16 304 4.6E-57 T 14-10-2018 IPR023210 NADP-dependent oxidoreductase domain MB46_03060 7d959da0571091f13b6f5cec8a805c97 785 SMART SM00710 359 381 130.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat MB46_03060 7d959da0571091f13b6f5cec8a805c97 785 SMART SM00710 534 558 390.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat MB46_03060 7d959da0571091f13b6f5cec8a805c97 785 SMART SM00710 303 338 9600.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat MB46_03060 7d959da0571091f13b6f5cec8a805c97 785 SMART SM00710 478 500 880.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat MB46_03060 7d959da0571091f13b6f5cec8a805c97 785 SMART SM00710 501 523 4200.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat MB46_03060 7d959da0571091f13b6f5cec8a805c97 785 Gene3D G3DSA:2.160.20.10 435 660 9.9E-11 T 14-10-2018 IPR012334 Pectin lyase fold MB46_03060 7d959da0571091f13b6f5cec8a805c97 785 SUPERFAMILY SSF51126 51 606 6.71E-33 T 14-10-2018 IPR011050 Pectin lyase fold/virulence factor MB46_00445 92b57cf3ef0c7cb4bce818d5307b601f 489 ProSitePatterns PS00609 Glycosyl hydrolases family 32 active site. 14 27 - T 14-10-2018 IPR018053 Glycoside hydrolase, family 32, active site GO:0004553|GO:0005975 KEGG: 00052+3.2.1.26|KEGG: 00500+3.2.1.26 MB46_00445 92b57cf3ef0c7cb4bce818d5307b601f 489 Gene3D G3DSA:2.115.10.20 8 321 1.4E-113 T 14-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily MB46_00445 92b57cf3ef0c7cb4bce818d5307b601f 489 Pfam PF00251 Glycosyl hydrolases family 32 N-terminal domain 14 320 5.6E-87 T 14-10-2018 IPR013148 Glycosyl hydrolase family 32, N-terminal MB46_00445 92b57cf3ef0c7cb4bce818d5307b601f 489 SUPERFAMILY SSF75005 9 320 2.04E-95 T 14-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily MB46_00445 92b57cf3ef0c7cb4bce818d5307b601f 489 SMART SM00640 14 436 6.8E-99 T 14-10-2018 IPR001362 Glycoside hydrolase, family 32 GO:0004553|GO:0005975 MB46_00445 92b57cf3ef0c7cb4bce818d5307b601f 489 SUPERFAMILY SSF49899 350 459 4.43E-6 T 14-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily MB46_00445 92b57cf3ef0c7cb4bce818d5307b601f 489 Pfam PF08244 Glycosyl hydrolases family 32 C terminal 353 444 9.2E-6 T 14-10-2018 IPR013189 Glycosyl hydrolase family 32, C-terminal MB46_00445 92b57cf3ef0c7cb4bce818d5307b601f 489 Gene3D G3DSA:2.60.120.560 338 471 7.2E-10 T 14-10-2018 MB46_13840 600a0d9ea5cc83a171bc2933aa298d69 224 Gene3D G3DSA:3.40.50.2300 1 121 2.6E-36 T 14-10-2018 MB46_13840 600a0d9ea5cc83a171bc2933aa298d69 224 Gene3D G3DSA:1.10.10.10 122 223 2.6E-29 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_13840 600a0d9ea5cc83a171bc2933aa298d69 224 Pfam PF00072 Response regulator receiver domain 4 112 1.3E-28 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MB46_13840 600a0d9ea5cc83a171bc2933aa298d69 224 SMART SM00862 146 222 8.0E-24 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MB46_13840 600a0d9ea5cc83a171bc2933aa298d69 224 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 222 1.9E-22 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MB46_13840 600a0d9ea5cc83a171bc2933aa298d69 224 SUPERFAMILY SSF52172 1 175 1.18E-41 T 14-10-2018 IPR011006 CheY-like superfamily MB46_13840 600a0d9ea5cc83a171bc2933aa298d69 224 SMART SM00448 2 112 5.7E-42 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MB46_13775 e859f839b28b0a50e7e0450fd92f6be3 297 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_13775 e859f839b28b0a50e7e0450fd92f6be3 297 Pfam PF00005 ABC transporter 38 178 2.5E-31 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_13775 e859f839b28b0a50e7e0450fd92f6be3 297 Gene3D G3DSA:3.40.50.300 24 281 4.0E-64 T 14-10-2018 MB46_13775 e859f839b28b0a50e7e0450fd92f6be3 297 SUPERFAMILY SSF52540 34 230 1.82E-69 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_13775 e859f839b28b0a50e7e0450fd92f6be3 297 SMART SM00382 47 240 4.4E-18 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_10005 a395d812f667e629b3b62d09b75556bd 217 Pfam PF00072 Response regulator receiver domain 6 118 1.7E-28 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MB46_10005 a395d812f667e629b3b62d09b75556bd 217 ProSitePatterns PS00622 LuxR-type HTH domain signature. 172 199 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_10005 a395d812f667e629b3b62d09b75556bd 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 188 200 5.9E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_10005 a395d812f667e629b3b62d09b75556bd 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 172 188 5.9E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_10005 a395d812f667e629b3b62d09b75556bd 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 158 172 5.9E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_10005 a395d812f667e629b3b62d09b75556bd 217 SMART SM00421 155 212 2.8E-21 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_10005 a395d812f667e629b3b62d09b75556bd 217 Pfam PF00196 Bacterial regulatory proteins, luxR family 157 211 4.1E-18 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_10005 a395d812f667e629b3b62d09b75556bd 217 Gene3D G3DSA:3.40.50.12740 4 216 4.1E-67 T 14-10-2018 MB46_10005 a395d812f667e629b3b62d09b75556bd 217 SUPERFAMILY SSF52172 3 135 5.41E-34 T 14-10-2018 IPR011006 CheY-like superfamily MB46_10005 a395d812f667e629b3b62d09b75556bd 217 SUPERFAMILY SSF46894 151 214 1.84E-18 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MB46_10005 a395d812f667e629b3b62d09b75556bd 217 SMART SM00448 4 117 9.2E-32 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MB46_01730 3ffd5debaff8d5aebdae3d0e3265c0bb 237 PIRSF PIRSF039137 1 237 3.2E-110 T 14-10-2018 IPR030660 High-affinity branched-chain amino acid transport ATP-binding protein GO:0015658|GO:0015803 MB46_01730 3ffd5debaff8d5aebdae3d0e3265c0bb 237 SMART SM00382 28 215 2.8E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_01730 3ffd5debaff8d5aebdae3d0e3265c0bb 237 SUPERFAMILY SSF52540 3 233 4.49E-59 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_01730 3ffd5debaff8d5aebdae3d0e3265c0bb 237 Gene3D G3DSA:3.40.50.300 1 237 4.2E-65 T 14-10-2018 MB46_01730 3ffd5debaff8d5aebdae3d0e3265c0bb 237 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_01730 3ffd5debaff8d5aebdae3d0e3265c0bb 237 Pfam PF00005 ABC transporter 20 164 2.1E-29 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_19745 2e7ac3812a6e7d010e7cf7374c253b08 342 SUPERFAMILY SSF52540 34 166 4.28E-15 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_19745 2e7ac3812a6e7d010e7cf7374c253b08 342 Gene3D G3DSA:3.40.50.300 2 157 1.8E-19 T 14-10-2018 MB46_19745 2e7ac3812a6e7d010e7cf7374c253b08 342 Pfam PF03969 AFG1-like ATPase 44 336 1.2E-83 T 14-10-2018 IPR005654 ATPase, AFG1-like GO:0005524 MB46_00695 4cad123c72c8cbf3b196c48c6c2d10b4 263 SUPERFAMILY SSF51621 2 239 5.08E-49 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 MB46_00695 4cad123c72c8cbf3b196c48c6c2d10b4 263 Gene3D G3DSA:3.20.20.60 1 256 1.1E-62 T 14-10-2018 MB46_00695 4cad123c72c8cbf3b196c48c6c2d10b4 263 Pfam PF13714 Phosphoenolpyruvate phosphomutase 4 233 3.0E-68 T 14-10-2018 MB46_03945 c95e64abaa35712dc5c91ab9a9b9004a 519 Gene3D G3DSA:3.40.50.11060 109 231 6.5E-41 T 14-10-2018 MB46_03945 c95e64abaa35712dc5c91ab9a9b9004a 519 Pfam PF16360 GTP-binding GTPase Middle Region 206 292 1.2E-28 T 14-10-2018 IPR032305 GTP-binding protein, middle domain MB46_03945 c95e64abaa35712dc5c91ab9a9b9004a 519 Pfam PF01926 50S ribosome-binding GTPase 300 418 1.5E-19 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 MB46_03945 c95e64abaa35712dc5c91ab9a9b9004a 519 Hamap MF_00900 GTPase HflX [hflX]. 119 488 47.977 T 14-10-2018 IPR016496 GTPase HflX GO:0005525 MB46_03945 c95e64abaa35712dc5c91ab9a9b9004a 519 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 101 458 6.7E-132 T 14-10-2018 IPR016496 GTPase HflX GO:0005525 MB46_03945 c95e64abaa35712dc5c91ab9a9b9004a 519 Pfam PF13167 GTP-binding GTPase N-terminal 116 204 2.2E-32 T 14-10-2018 IPR025121 GTPase HflX, N-terminal MB46_03945 c95e64abaa35712dc5c91ab9a9b9004a 519 PIRSF PIRSF006809 92 519 7.2E-153 T 14-10-2018 IPR016496 GTPase HflX GO:0005525 MB46_03945 c95e64abaa35712dc5c91ab9a9b9004a 519 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 300 320 8.1E-7 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 MB46_03945 c95e64abaa35712dc5c91ab9a9b9004a 519 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 367 385 8.1E-7 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 MB46_03945 c95e64abaa35712dc5c91ab9a9b9004a 519 SUPERFAMILY SSF52540 291 461 5.91E-42 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_03945 c95e64abaa35712dc5c91ab9a9b9004a 519 Gene3D G3DSA:3.40.50.300 297 462 3.8E-42 T 14-10-2018 MB46_18405 797b6216441664c88ebfa2acbabcbf1e 259 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 200 0.0072 T 14-10-2018 MB46_18405 797b6216441664c88ebfa2acbabcbf1e 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 3.8E-30 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_18405 797b6216441664c88ebfa2acbabcbf1e 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 139 155 3.8E-30 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_18405 797b6216441664c88ebfa2acbabcbf1e 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 3.8E-30 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_18405 797b6216441664c88ebfa2acbabcbf1e 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 184 3.8E-30 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_18405 797b6216441664c88ebfa2acbabcbf1e 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 186 203 3.8E-30 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_18405 797b6216441664c88ebfa2acbabcbf1e 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 220 240 3.8E-30 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_18405 797b6216441664c88ebfa2acbabcbf1e 259 SUPERFAMILY SSF51735 6 256 8.7E-59 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_18405 797b6216441664c88ebfa2acbabcbf1e 259 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 152 180 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MB46_18405 797b6216441664c88ebfa2acbabcbf1e 259 Gene3D G3DSA:3.40.50.720 5 259 1.9E-72 T 14-10-2018 MB46_18405 797b6216441664c88ebfa2acbabcbf1e 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 165 184 3.9E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_18405 797b6216441664c88ebfa2acbabcbf1e 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 145 153 3.9E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_18405 797b6216441664c88ebfa2acbabcbf1e 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 3.9E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_18405 797b6216441664c88ebfa2acbabcbf1e 259 Pfam PF00106 short chain dehydrogenase 9 206 1.3E-46 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_12960 40ec0ad2f7814eddf335193b3ea92360 1397 Gene3D G3DSA:3.40.50.300 919 1109 8.5E-7 T 14-10-2018 MB46_12960 40ec0ad2f7814eddf335193b3ea92360 1397 Gene3D G3DSA:3.40.50.300 235 572 4.0E-9 T 14-10-2018 MB46_12960 40ec0ad2f7814eddf335193b3ea92360 1397 SUPERFAMILY SSF52540 290 1102 1.24E-19 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_16165 ad0a83051318f51b675a99bbf16468ca 289 SUPERFAMILY SSF144091 75 256 1.57E-45 T 14-10-2018 MB46_16165 ad0a83051318f51b675a99bbf16468ca 289 Pfam PF01694 Rhomboid family 114 249 1.0E-34 T 14-10-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 MB46_16165 ad0a83051318f51b675a99bbf16468ca 289 Gene3D G3DSA:1.20.1540.10 72 261 7.5E-46 T 14-10-2018 IPR035952 Rhomboid-like superfamily MB46_16165 ad0a83051318f51b675a99bbf16468ca 289 SUPERFAMILY SSF57845 10 43 3.66E-5 T 14-10-2018 MB46_11985 ceae21b3031b1b960ac052c07497a0a4 1166 Gene3D G3DSA:3.40.50.300 251 388 3.7E-32 T 14-10-2018 MB46_11985 ceae21b3031b1b960ac052c07497a0a4 1166 Pfam PF13361 UvrD-like helicase C-terminal domain 400 830 2.0E-30 T 14-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 MB46_11985 ceae21b3031b1b960ac052c07497a0a4 1166 SUPERFAMILY SSF52980 1003 1133 1.02E-5 T 14-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 MB46_11985 ceae21b3031b1b960ac052c07497a0a4 1166 Pfam PF00580 UvrD/REP helicase N-terminal domain 40 349 1.0E-51 T 14-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 MB46_11985 ceae21b3031b1b960ac052c07497a0a4 1166 SUPERFAMILY SSF52540 38 852 1.76E-115 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_11985 ceae21b3031b1b960ac052c07497a0a4 1166 Gene3D G3DSA:3.40.50.300 36 216 9.4E-34 T 14-10-2018 MB46_11985 ceae21b3031b1b960ac052c07497a0a4 1166 Pfam PF12705 PD-(D/E)XK nuclease superfamily 1000 1143 3.4E-11 T 14-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type MB46_11985 ceae21b3031b1b960ac052c07497a0a4 1166 Gene3D G3DSA:3.40.50.300 440 542 2.1E-18 T 14-10-2018 MB46_11985 ceae21b3031b1b960ac052c07497a0a4 1166 Gene3D G3DSA:3.90.320.10 1039 1145 1.0E-5 T 14-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal MB46_13275 569a782d13115049c7d3e2bfe96cfdb0 164 SUPERFAMILY SSF64263 1 117 3.4E-42 T 14-10-2018 IPR036373 Ribosomal protein L17 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_13275 569a782d13115049c7d3e2bfe96cfdb0 164 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 5 116 24.473 T 14-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_13275 569a782d13115049c7d3e2bfe96cfdb0 164 Pfam PF01196 Ribosomal protein L17 20 116 1.6E-32 T 14-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_13275 569a782d13115049c7d3e2bfe96cfdb0 164 Gene3D G3DSA:3.90.1030.10 1 116 2.7E-39 T 14-10-2018 IPR036373 Ribosomal protein L17 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_13275 569a782d13115049c7d3e2bfe96cfdb0 164 TIGRFAM TIGR00059 L17: ribosomal protein bL17 9 116 2.6E-35 T 14-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_13275 569a782d13115049c7d3e2bfe96cfdb0 164 ProSitePatterns PS01167 Ribosomal protein L17 signature. 34 56 - T 14-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_16800 f25829c27986734ce5e631433d2c5b78 322 Gene3D G3DSA:3.40.50.620 2 182 2.8E-22 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MB46_16800 f25829c27986734ce5e631433d2c5b78 322 PIRSF PIRSF000089 1 322 7.1E-87 T 14-10-2018 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 MB46_16800 f25829c27986734ce5e631433d2c5b78 322 SUPERFAMILY SSF52402 3 167 3.84E-24 T 14-10-2018 MB46_16800 f25829c27986734ce5e631433d2c5b78 322 ProSitePatterns PS00696 Electron transfer flavoprotein alpha-subunit signature. 262 288 - T 14-10-2018 IPR018206 Electron transfer flavoprotein subunit alpha, conserved site Reactome: R-HSA-611105 MB46_16800 f25829c27986734ce5e631433d2c5b78 322 SMART SM00893 4 186 7.1E-8 T 14-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 MB46_16800 f25829c27986734ce5e631433d2c5b78 322 SUPERFAMILY SSF52467 199 317 3.74E-47 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily MB46_16800 f25829c27986734ce5e631433d2c5b78 322 Gene3D G3DSA:3.40.50.1220 192 322 3.2E-56 T 14-10-2018 MB46_16800 f25829c27986734ce5e631433d2c5b78 322 Pfam PF01012 Electron transfer flavoprotein domain 5 191 1.9E-17 T 14-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 MB46_16800 f25829c27986734ce5e631433d2c5b78 322 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 200 280 5.8E-35 T 14-10-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 MB46_11540 fa0f18bc851679fae2be05293d629b4a 242 SUPERFAMILY SSF52540 40 238 3.42E-42 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_11540 fa0f18bc851679fae2be05293d629b4a 242 Pfam PF00005 ABC transporter 44 175 1.2E-16 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_11540 fa0f18bc851679fae2be05293d629b4a 242 SMART SM00382 53 225 3.4E-7 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_11540 fa0f18bc851679fae2be05293d629b4a 242 Gene3D G3DSA:3.40.50.300 4 241 6.5E-39 T 14-10-2018 MB46_05275 1481f8023e58f17c862e25dd4ea32422 479 SUPERFAMILY SSF51735 137 427 1.32E-29 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_05275 1481f8023e58f17c862e25dd4ea32422 479 Gene3D G3DSA:3.40.50.720 315 457 1.5E-15 T 14-10-2018 MB46_05275 1481f8023e58f17c862e25dd4ea32422 479 Gene3D G3DSA:3.40.50.720 129 252 1.5E-16 T 14-10-2018 MB46_05275 1481f8023e58f17c862e25dd4ea32422 479 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 327 424 1.4E-6 T 14-10-2018 MB46_05275 1481f8023e58f17c862e25dd4ea32422 479 Pfam PF00106 short chain dehydrogenase 141 231 8.1E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_05890 357ddec7a8bbabe2191f22fff5bbcf00 123 SUPERFAMILY SSF54593 7 122 6.6E-20 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MB46_05890 357ddec7a8bbabe2191f22fff5bbcf00 123 Gene3D G3DSA:3.10.180.10 6 123 4.5E-15 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MB46_05890 357ddec7a8bbabe2191f22fff5bbcf00 123 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 8 116 1.1E-7 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MB46_01275 0653046a19b03831e8257959058bed09 350 SUPERFAMILY SSF53474 68 325 3.77E-8 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_19705 32c5554fecc54888af311aebfb6dbfff 140 Gene3D G3DSA:3.10.180.10 8 138 7.3E-23 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MB46_19705 32c5554fecc54888af311aebfb6dbfff 140 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 16 125 1.6E-11 T 14-10-2018 MB46_19705 32c5554fecc54888af311aebfb6dbfff 140 SUPERFAMILY SSF54593 13 139 2.02E-11 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MB46_11195 8060dfddd42b77cc5f35d6661aed2598 499 Gene3D G3DSA:3.20.20.70 5 496 5.1E-130 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MB46_11195 8060dfddd42b77cc5f35d6661aed2598 499 SMART SM01240 9 495 7.8E-175 T 14-10-2018 MB46_11195 8060dfddd42b77cc5f35d6661aed2598 499 PIRSF PIRSF000130 1 499 5.9E-133 T 14-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 MB46_11195 8060dfddd42b77cc5f35d6661aed2598 499 SUPERFAMILY SSF51412 10 494 6.54E-91 T 14-10-2018 MB46_11195 8060dfddd42b77cc5f35d6661aed2598 499 SUPERFAMILY SSF54631 97 222 9.21E-10 T 14-10-2018 MB46_11195 8060dfddd42b77cc5f35d6661aed2598 499 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 11 494 5.1E-98 T 14-10-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 MB46_01500 36ab5d405ac646449a01edc3c0c994fb 332 Gene3D G3DSA:2.60.120.10 246 329 1.8E-10 T 14-10-2018 IPR014710 RmlC-like jelly roll fold MB46_01500 36ab5d405ac646449a01edc3c0c994fb 332 SUPERFAMILY SSF51182 11 330 1.48E-44 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily MB46_01500 36ab5d405ac646449a01edc3c0c994fb 332 Gene3D G3DSA:2.60.120.10 6 214 1.4E-35 T 14-10-2018 IPR014710 RmlC-like jelly roll fold MB46_05345 6bb322ac944d9d83fea77f15fe716635 385 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 242 364 4.6E-16 T 14-10-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain MB46_05345 6bb322ac944d9d83fea77f15fe716635 385 SUPERFAMILY SSF56645 13 218 1.28E-34 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 MB46_05345 6bb322ac944d9d83fea77f15fe716635 385 Gene3D G3DSA:1.10.540.10 5 115 1.1E-16 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 MB46_05345 6bb322ac944d9d83fea77f15fe716635 385 PIRSF PIRSF016578 2 385 9.5E-35 T 14-10-2018 MB46_05345 6bb322ac944d9d83fea77f15fe716635 385 Gene3D G3DSA:1.20.140.10 228 379 4.2E-28 T 14-10-2018 MB46_05345 6bb322ac944d9d83fea77f15fe716635 385 SUPERFAMILY SSF47203 231 381 6.6E-21 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 MB46_05345 6bb322ac944d9d83fea77f15fe716635 385 Gene3D G3DSA:2.40.110.10 116 220 6.5E-21 T 14-10-2018 MB46_04890 59fb6d20e4429ceced929f42b3a5ccb4 509 Gene3D G3DSA:3.30.750.24 409 505 3.5E-27 T 14-10-2018 IPR036513 STAS domain superfamily MB46_04890 59fb6d20e4429ceced929f42b3a5ccb4 509 SUPERFAMILY SSF52091 424 496 1.82E-11 T 14-10-2018 IPR036513 STAS domain superfamily MB46_04890 59fb6d20e4429ceced929f42b3a5ccb4 509 Pfam PF00916 Sulfate permease family 34 164 3.5E-22 T 14-10-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 MB46_04890 59fb6d20e4429ceced929f42b3a5ccb4 509 Pfam PF00916 Sulfate permease family 171 378 1.6E-25 T 14-10-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 MB46_04890 59fb6d20e4429ceced929f42b3a5ccb4 509 Pfam PF01740 STAS domain 428 497 4.5E-6 T 14-10-2018 IPR002645 STAS domain MB46_03160 d092f92ab6db44cf4983d80932f9c074 411 Pfam PF09375 Imelysin 167 402 5.6E-33 T 14-10-2018 IPR018976 Imelysin-like domain MB46_03160 d092f92ab6db44cf4983d80932f9c074 411 Gene3D G3DSA:1.20.1420.20 159 410 7.8E-77 T 14-10-2018 IPR038352 Imelysin-like domain superfamily MB46_18715 ff4f014d9c16d3a064a4a13ae74f7704 212 Hamap MF_01218_B Uracil phosphoribosyltransferase [upp]. 2 211 42.289 T 14-10-2018 IPR034332 Uracil phosphoribosyltransferase, bacterial-type KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 MB46_18715 ff4f014d9c16d3a064a4a13ae74f7704 212 SUPERFAMILY SSF53271 3 209 1.31E-62 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like MB46_18715 ff4f014d9c16d3a064a4a13ae74f7704 212 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 4 210 1.6E-73 T 14-10-2018 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 MB46_18715 ff4f014d9c16d3a064a4a13ae74f7704 212 Gene3D G3DSA:3.40.50.2020 1 210 1.1E-72 T 14-10-2018 MB46_18715 ff4f014d9c16d3a064a4a13ae74f7704 212 Pfam PF14681 Uracil phosphoribosyltransferase 5 209 4.5E-63 T 14-10-2018 MB46_11970 40d7cc38c6caa93f1d4c1e90d84202b1 703 Gene3D G3DSA:1.10.486.10 398 418 1.2E-25 T 14-10-2018 MB46_11970 40d7cc38c6caa93f1d4c1e90d84202b1 703 Gene3D G3DSA:1.10.150.80 632 703 2.3E-20 T 14-10-2018 MB46_11970 40d7cc38c6caa93f1d4c1e90d84202b1 703 SMART SM00341 630 702 2.4E-8 T 14-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 MB46_11970 40d7cc38c6caa93f1d4c1e90d84202b1 703 Gene3D G3DSA:3.40.50.300 288 396 1.2E-25 T 14-10-2018 MB46_11970 40d7cc38c6caa93f1d4c1e90d84202b1 703 Gene3D G3DSA:3.40.50.300 489 576 1.4E-33 T 14-10-2018 MB46_11970 40d7cc38c6caa93f1d4c1e90d84202b1 703 Gene3D G3DSA:1.10.486.10 419 488 1.4E-33 T 14-10-2018 MB46_11970 40d7cc38c6caa93f1d4c1e90d84202b1 703 Gene3D G3DSA:3.40.50.300 14 279 2.4E-70 T 14-10-2018 MB46_11970 40d7cc38c6caa93f1d4c1e90d84202b1 703 Gene3D G3DSA:1.10.10.160 112 195 2.4E-70 T 14-10-2018 IPR013986 DExx box DNA helicase domain superfamily MB46_11970 40d7cc38c6caa93f1d4c1e90d84202b1 703 SUPERFAMILY SSF47819 624 702 3.92E-21 T 14-10-2018 IPR010997 HRDC-like superfamily GO:0000166|GO:0003824|GO:0044237 MB46_11970 40d7cc38c6caa93f1d4c1e90d84202b1 703 Pfam PF13245 AAA domain 20 262 6.3E-34 T 14-10-2018 MB46_11970 40d7cc38c6caa93f1d4c1e90d84202b1 703 Pfam PF13361 UvrD-like helicase C-terminal domain 446 559 1.4E-21 T 14-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 MB46_11970 40d7cc38c6caa93f1d4c1e90d84202b1 703 Pfam PF13361 UvrD-like helicase C-terminal domain 284 426 1.8E-17 T 14-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 MB46_11970 40d7cc38c6caa93f1d4c1e90d84202b1 703 Pfam PF00570 HRDC domain 634 700 9.0E-21 T 14-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 MB46_11970 40d7cc38c6caa93f1d4c1e90d84202b1 703 SUPERFAMILY SSF52540 8 580 1.57E-119 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_06475 197a6a00e1e8c7864506d94c91d0a0a7 243 Pfam PF03932 CutC family 1 206 4.9E-51 T 14-10-2018 IPR023648 Copper homeostasis CutC domain GO:0005507|GO:0055070 Reactome: R-HSA-936837 MB46_06475 197a6a00e1e8c7864506d94c91d0a0a7 243 SUPERFAMILY SSF110395 1 233 6.41E-51 T 14-10-2018 IPR036822 Copper homeostasis (CutC) domain superfamily GO:0005507|GO:0055070 Reactome: R-HSA-936837 MB46_06475 197a6a00e1e8c7864506d94c91d0a0a7 243 Hamap MF_00795 Copper homeostasis protein CutC [cutC]. 1 208 25.912 T 14-10-2018 IPR005627 Copper homeostasis protein CutC GO:0005507|GO:0055070 Reactome: R-HSA-936837 MB46_06475 197a6a00e1e8c7864506d94c91d0a0a7 243 Gene3D G3DSA:3.20.20.380 1 238 3.9E-65 T 14-10-2018 IPR036822 Copper homeostasis (CutC) domain superfamily GO:0005507|GO:0055070 Reactome: R-HSA-936837 MB46_17735 42b59ce951b0e13a93aec32b819da320 78 Gene3D G3DSA:1.10.1660.10 10 61 8.6E-13 T 14-10-2018 MB46_17735 42b59ce951b0e13a93aec32b819da320 78 SUPERFAMILY SSF46955 12 60 1.04E-6 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily MB46_17735 42b59ce951b0e13a93aec32b819da320 78 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 12 59 3.3E-21 T 14-10-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 MB46_17735 42b59ce951b0e13a93aec32b819da320 78 Pfam PF12728 Helix-turn-helix domain 12 60 3.7E-17 T 14-10-2018 MB46_19885 5da58dd430b311c99ab1436302fb42a5 668 SUPERFAMILY SSF53300 1 178 1.21E-6 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily MB46_19885 5da58dd430b311c99ab1436302fb42a5 668 Gene3D G3DSA:3.40.50.410 1 227 1.6E-8 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily MB46_19885 5da58dd430b311c99ab1436302fb42a5 668 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 251 279 9.1E-4 T 14-10-2018 IPR001434 Domain of unknown function DUF11 MB46_19885 5da58dd430b311c99ab1436302fb42a5 668 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 498 531 3.8E-4 T 14-10-2018 IPR001434 Domain of unknown function DUF11 MB46_19885 5da58dd430b311c99ab1436302fb42a5 668 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 379 405 7.6E-5 T 14-10-2018 IPR001434 Domain of unknown function DUF11 MB46_09825 002b1839c8ee603de9b255bd61316924 338 Gene3D G3DSA:3.30.1330.10 1 154 2.9E-38 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily MB46_09825 002b1839c8ee603de9b255bd61316924 338 TIGRFAM TIGR01379 thiL: thiamine-phosphate kinase 10 336 6.6E-65 T 14-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 MB46_09825 002b1839c8ee603de9b255bd61316924 338 SUPERFAMILY SSF55326 7 152 6.28E-25 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily MB46_09825 002b1839c8ee603de9b255bd61316924 338 SUPERFAMILY SSF56042 157 306 8.16E-23 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily MB46_09825 002b1839c8ee603de9b255bd61316924 338 Pfam PF00586 AIR synthase related protein, N-terminal domain 33 151 1.2E-16 T 14-10-2018 IPR016188 PurM-like, N-terminal domain MB46_09825 002b1839c8ee603de9b255bd61316924 338 Pfam PF02769 AIR synthase related protein, C-terminal domain 164 259 1.0E-5 T 14-10-2018 IPR010918 PurM-like, C-terminal domain MB46_09825 002b1839c8ee603de9b255bd61316924 338 Gene3D G3DSA:3.90.650.10 159 336 1.3E-41 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily MB46_09825 002b1839c8ee603de9b255bd61316924 338 Hamap MF_02128 Thiamine-monophosphate kinase [thiL]. 8 336 23.533 T 14-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 MB46_09825 002b1839c8ee603de9b255bd61316924 338 PIRSF PIRSF005303 3 336 8.7E-68 T 14-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 MB46_17065 321debaf3bfc7f81afe36ed953ac9764 274 SUPERFAMILY SSF53335 11 220 1.69E-40 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MB46_17065 321debaf3bfc7f81afe36ed953ac9764 274 Gene3D G3DSA:3.40.50.150 9 252 1.8E-39 T 14-10-2018 MB46_17065 321debaf3bfc7f81afe36ed953ac9764 274 Pfam PF13847 Methyltransferase domain 43 178 1.4E-27 T 14-10-2018 IPR025714 Methyltransferase domain MB46_15790 dae386c69081781efd5602abd874ff3a 397 Pfam PF05816 Toxic anion resistance protein (TelA) 64 390 1.7E-89 T 14-10-2018 IPR008863 Toxic anion resistance MB46_06825 f105304cd44134fd0258e115158483ff 377 SUPERFAMILY SSF51182 29 368 4.75E-104 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily MB46_06825 f105304cd44134fd0258e115158483ff 377 Pfam PF07883 Cupin domain 117 181 1.8E-19 T 14-10-2018 IPR013096 Cupin 2, conserved barrel MB46_06825 f105304cd44134fd0258e115158483ff 377 Gene3D G3DSA:2.60.120.10 25 376 1.0E-114 T 14-10-2018 IPR014710 RmlC-like jelly roll fold MB46_05915 60d96daa7ebdc2a079f069e1061f8699 140 Gene3D G3DSA:3.30.160.20 3 137 1.4E-27 T 14-10-2018 MB46_05915 60d96daa7ebdc2a079f069e1061f8699 140 Pfam PF00472 RF-1 domain 9 133 8.9E-21 T 14-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 MB46_05915 60d96daa7ebdc2a079f069e1061f8699 140 SUPERFAMILY SSF75620 8 94 1.49E-11 T 14-10-2018 MB46_11945 8063383454c195f8f6bf72f5b9d3b1be 977 Hamap MF_01600 UPF0182 protein . 1 888 18.63 T 14-10-2018 IPR005372 Uncharacterised protein family UPF0182 GO:0016021 MB46_11945 8063383454c195f8f6bf72f5b9d3b1be 977 Pfam PF03699 Uncharacterised protein family (UPF0182) 3 811 5.5E-281 T 14-10-2018 IPR005372 Uncharacterised protein family UPF0182 GO:0016021 MB46_17330 ef70cb54bcdc970999d7b141df43c979 225 PRINTS PR00103 cAMP-dependent protein kinase signature 32 46 2.5E-5 T 14-10-2018 MB46_17330 ef70cb54bcdc970999d7b141df43c979 225 PRINTS PR00103 cAMP-dependent protein kinase signature 77 86 2.5E-5 T 14-10-2018 MB46_17330 ef70cb54bcdc970999d7b141df43c979 225 PRINTS PR00103 cAMP-dependent protein kinase signature 89 100 2.5E-5 T 14-10-2018 MB46_17330 ef70cb54bcdc970999d7b141df43c979 225 SMART SM00100 11 129 4.2E-29 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain MB46_17330 ef70cb54bcdc970999d7b141df43c979 225 Gene3D G3DSA:2.60.120.10 2 147 1.8E-50 T 14-10-2018 IPR014710 RmlC-like jelly roll fold MB46_17330 ef70cb54bcdc970999d7b141df43c979 225 SMART SM00419 168 216 2.0E-13 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 MB46_17330 ef70cb54bcdc970999d7b141df43c979 225 Pfam PF00027 Cyclic nucleotide-binding domain 30 116 7.4E-25 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain MB46_17330 ef70cb54bcdc970999d7b141df43c979 225 Pfam PF13545 Crp-like helix-turn-helix domain 149 222 4.6E-17 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 MB46_17330 ef70cb54bcdc970999d7b141df43c979 225 SUPERFAMILY SSF51206 5 143 1.31E-38 T 14-10-2018 IPR018490 Cyclic nucleotide-binding-like MB46_17330 ef70cb54bcdc970999d7b141df43c979 225 Gene3D G3DSA:1.10.10.10 148 225 4.2E-30 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_17330 ef70cb54bcdc970999d7b141df43c979 225 SUPERFAMILY SSF46785 146 223 1.59E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_12620 1e2284e2db604c11079a53e55963263d 230 SUPERFAMILY SSF53254 1 201 1.52E-43 T 14-10-2018 IPR029033 Histidine phosphatase superfamily MB46_12620 1e2284e2db604c11079a53e55963263d 230 Gene3D G3DSA:3.40.50.1240 1 207 3.0E-44 T 14-10-2018 IPR029033 Histidine phosphatase superfamily MB46_12620 1e2284e2db604c11079a53e55963263d 230 TIGRFAM TIGR03848 MSMEG_4193: probable phosphomutase, MSMEG_4193 family 3 208 8.4E-93 T 14-10-2018 IPR022492 Phosphomutase MSMEG4193, putative MB46_12620 1e2284e2db604c11079a53e55963263d 230 SMART SM00855 3 163 2.6E-19 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MB46_12620 1e2284e2db604c11079a53e55963263d 230 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 201 1.7E-44 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MB46_14285 6a14e4b14c3c626d80591ce441d6bae6 143 SUPERFAMILY SSF160631 4 133 1.7E-6 T 14-10-2018 MB46_12850 da8404fca9307378b55da03c246a6c48 293 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 2 57 2.6E-21 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MB46_12850 da8404fca9307378b55da03c246a6c48 293 SUPERFAMILY SSF46785 2 77 1.4E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_12850 da8404fca9307378b55da03c246a6c48 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 45 1.3E-10 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MB46_12850 da8404fca9307378b55da03c246a6c48 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 24 34 1.3E-10 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MB46_12850 da8404fca9307378b55da03c246a6c48 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 13 24 1.3E-10 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MB46_12850 da8404fca9307378b55da03c246a6c48 293 Gene3D G3DSA:1.10.10.10 1 77 1.3E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_12850 da8404fca9307378b55da03c246a6c48 293 Pfam PF03466 LysR substrate binding domain 90 287 9.7E-21 T 14-10-2018 IPR005119 LysR, substrate-binding MB46_12850 da8404fca9307378b55da03c246a6c48 293 Gene3D G3DSA:3.40.190.10 158 262 6.5E-33 T 14-10-2018 MB46_12850 da8404fca9307378b55da03c246a6c48 293 SUPERFAMILY SSF53850 90 286 3.44E-20 T 14-10-2018 MB46_12850 da8404fca9307378b55da03c246a6c48 293 Gene3D G3DSA:3.40.190.10 93 285 6.5E-33 T 14-10-2018 MB46_03195 0a83d7c15085101e6cebc6cc847c162f 440 Gene3D G3DSA:3.90.1150.10 301 440 7.5E-48 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MB46_03195 0a83d7c15085101e6cebc6cc847c162f 440 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 201 215 - T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 MB46_03195 0a83d7c15085101e6cebc6cc847c162f 440 SUPERFAMILY SSF53383 5 432 4.73E-113 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MB46_03195 0a83d7c15085101e6cebc6cc847c162f 440 Gene3D G3DSA:3.40.640.10 6 297 9.3E-99 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MB46_03195 0a83d7c15085101e6cebc6cc847c162f 440 PIRSF PIRSF001434 1 436 3.3E-126 T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 MB46_03195 0a83d7c15085101e6cebc6cc847c162f 440 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 8 432 1.0E-133 T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 MB46_03195 0a83d7c15085101e6cebc6cc847c162f 440 TIGRFAM TIGR01326 OAH_OAS_sulfhy: O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase 7 432 4.3E-190 T 14-10-2018 IPR006235 O-acetylhomoserine/O-acetylserine sulfhydrylase GO:0006520|GO:0016765 MB46_07340 16ba3bb4d79abb9e229f92cce8ce4de2 607 SUPERFAMILY SSF116726 316 398 4.05E-6 T 14-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 MB46_07340 16ba3bb4d79abb9e229f92cce8ce4de2 607 Pfam PF03600 Citrate transporter 16 353 1.4E-25 T 14-10-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 MB46_07340 16ba3bb4d79abb9e229f92cce8ce4de2 607 SUPERFAMILY SSF116726 224 294 8.11E-6 T 14-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 MB46_07340 16ba3bb4d79abb9e229f92cce8ce4de2 607 Pfam PF03600 Citrate transporter 426 599 9.6E-21 T 14-10-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 MB46_13850 9bed71d27d5b3c5d6355e3d44748ce41 198 Hamap MF_00276 Potassium-transporting ATPase KdpC subunit [kdpC]. 5 189 29.896 T 14-10-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 MB46_13850 9bed71d27d5b3c5d6355e3d44748ce41 198 TIGRFAM TIGR00681 kdpC: K+-transporting ATPase, C subunit 6 187 4.5E-48 T 14-10-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 MB46_13850 9bed71d27d5b3c5d6355e3d44748ce41 198 PIRSF PIRSF001296 4 193 6.9E-60 T 14-10-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 MB46_13850 9bed71d27d5b3c5d6355e3d44748ce41 198 Pfam PF02669 K+-transporting ATPase, c chain 10 187 9.1E-61 T 14-10-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 MB46_00755 4d58dfd3699cd74a80867901706a5383 821 SUPERFAMILY SSF51445 291 635 9.66E-89 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily MB46_00755 4d58dfd3699cd74a80867901706a5383 821 Gene3D G3DSA:3.20.20.80 294 633 1.7E-102 T 14-10-2018 MB46_00755 4d58dfd3699cd74a80867901706a5383 821 Gene3D G3DSA:2.60.120.260 15 190 3.3E-55 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily MB46_00755 4d58dfd3699cd74a80867901706a5383 821 SUPERFAMILY SSF49303 191 294 1.35E-12 T 14-10-2018 IPR036156 Beta-Galactosidase/glucuronidase domain superfamily MB46_00755 4d58dfd3699cd74a80867901706a5383 821 Gene3D G3DSA:2.60.40.10 196 293 1.0E-8 T 14-10-2018 IPR013783 Immunoglobulin-like fold MB46_00755 4d58dfd3699cd74a80867901706a5383 821 SUPERFAMILY SSF49785 28 188 1.84E-44 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily MB46_03170 9b251d1278b6a9794776d86b5d62b586 217 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 1 196 2.2E-31 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MB46_03170 9b251d1278b6a9794776d86b5d62b586 217 SMART SM00855 1 158 5.9E-15 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MB46_03170 9b251d1278b6a9794776d86b5d62b586 217 SUPERFAMILY SSF53254 1 194 1.29E-36 T 14-10-2018 IPR029033 Histidine phosphatase superfamily MB46_03170 9b251d1278b6a9794776d86b5d62b586 217 Gene3D G3DSA:3.40.50.1240 1 199 1.6E-41 T 14-10-2018 IPR029033 Histidine phosphatase superfamily MB46_01040 95795af9b6d65ac9b673637750dc38b7 630 SUPERFAMILY SSF90123 30 348 5.49E-69 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MB46_01040 95795af9b6d65ac9b673637750dc38b7 630 Gene3D G3DSA:3.40.50.300 355 619 9.5E-84 T 14-10-2018 MB46_01040 95795af9b6d65ac9b673637750dc38b7 630 ProSitePatterns PS00211 ABC transporters family signature. 518 532 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_01040 95795af9b6d65ac9b673637750dc38b7 630 Pfam PF00664 ABC transporter transmembrane region 44 314 8.3E-40 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 MB46_01040 95795af9b6d65ac9b673637750dc38b7 630 Gene3D G3DSA:1.20.1560.10 13 347 1.8E-75 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MB46_01040 95795af9b6d65ac9b673637750dc38b7 630 SUPERFAMILY SSF52540 358 617 1.2E-83 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_01040 95795af9b6d65ac9b673637750dc38b7 630 SMART SM00382 406 592 2.2E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_01040 95795af9b6d65ac9b673637750dc38b7 630 Pfam PF00005 ABC transporter 397 546 1.4E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_06585 a9b0f60b8198bfa8a5011ff71a0927be 490 Gene3D G3DSA:1.20.1720.10 22 232 3.0E-36 T 14-10-2018 MB46_06585 a9b0f60b8198bfa8a5011ff71a0927be 490 Gene3D G3DSA:1.20.1250.20 280 469 2.8E-18 T 14-10-2018 MB46_06585 a9b0f60b8198bfa8a5011ff71a0927be 490 Pfam PF07690 Major Facilitator Superfamily 28 419 2.0E-45 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MB46_06585 a9b0f60b8198bfa8a5011ff71a0927be 490 SUPERFAMILY SSF103473 17 459 1.57E-57 T 14-10-2018 IPR036259 MFS transporter superfamily MB46_00070 8a967df2adcb37957783c4d78400266c 455 Pfam PF13224 Domain of unknown function (DUF4032) 261 422 2.7E-68 T 14-10-2018 IPR025111 Domain of unknown function DUF4032 MB46_00070 8a967df2adcb37957783c4d78400266c 455 SUPERFAMILY SSF56112 69 225 6.85E-9 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily MB46_01345 ad3c31df30414ff5b847d80da88e0a2f 327 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 116 326 1.8E-33 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_01345 ad3c31df30414ff5b847d80da88e0a2f 327 Gene3D G3DSA:1.10.3720.10 87 321 1.7E-15 T 14-10-2018 IPR035906 MetI-like superfamily MB46_01345 ad3c31df30414ff5b847d80da88e0a2f 327 SUPERFAMILY SSF161098 97 309 3.14E-14 T 14-10-2018 IPR035906 MetI-like superfamily MB46_11950 6341c9085a4cf056f760df5354a862cd 364 Gene3D G3DSA:3.30.230.10 190 354 7.4E-23 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MB46_11950 6341c9085a4cf056f760df5354a862cd 364 SUPERFAMILY SSF54211 200 348 1.9E-21 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MB46_11950 6341c9085a4cf056f760df5354a862cd 364 SUPERFAMILY SSF50156 147 224 1.19E-9 T 14-10-2018 IPR036034 PDZ superfamily GO:0005515 MB46_11950 6341c9085a4cf056f760df5354a862cd 364 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 256 343 5.4E-8 T 14-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 MB46_09100 511513d4d81574e5cbe40d9cdf6ff9b2 849 Pfam PF01433 Peptidase family M1 domain 209 442 5.4E-63 T 14-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 MB46_09100 511513d4d81574e5cbe40d9cdf6ff9b2 849 Gene3D G3DSA:1.10.390.60 200 464 2.3E-72 T 14-10-2018 MB46_09100 511513d4d81574e5cbe40d9cdf6ff9b2 849 Gene3D G3DSA:2.60.40.1730 15 194 3.2E-27 T 14-10-2018 MB46_09100 511513d4d81574e5cbe40d9cdf6ff9b2 849 TIGRFAM TIGR02412 pepN_strep_liv: aminopeptidase N 2 846 0.0 T 14-10-2018 IPR012778 Peptidase M1, aminopeptidase GO:0004177|GO:0006508 KEGG: 00480+3.4.11.2 MB46_09100 511513d4d81574e5cbe40d9cdf6ff9b2 849 SUPERFAMILY SSF63737 2 193 5.23E-41 T 14-10-2018 MB46_09100 511513d4d81574e5cbe40d9cdf6ff9b2 849 Pfam PF11838 ERAP1-like C-terminal domain 529 840 1.1E-49 T 14-10-2018 IPR024571 ERAP1-like C-terminal domain MB46_09100 511513d4d81574e5cbe40d9cdf6ff9b2 849 SUPERFAMILY SSF55486 205 452 9.38E-77 T 14-10-2018 MB46_09100 511513d4d81574e5cbe40d9cdf6ff9b2 849 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 176 191 1.4E-20 T 14-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 MB46_09100 511513d4d81574e5cbe40d9cdf6ff9b2 849 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 313 325 1.4E-20 T 14-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 MB46_09100 511513d4d81574e5cbe40d9cdf6ff9b2 849 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 260 270 1.4E-20 T 14-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 MB46_09100 511513d4d81574e5cbe40d9cdf6ff9b2 849 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 128 143 1.4E-20 T 14-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 MB46_09100 511513d4d81574e5cbe40d9cdf6ff9b2 849 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 294 309 1.4E-20 T 14-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 MB46_14120 a3a6b8858fce1ae159244374a0f2b24f 286 Pfam PF00892 EamA-like transporter family 13 123 4.4E-11 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MB46_14120 a3a6b8858fce1ae159244374a0f2b24f 286 SUPERFAMILY SSF103481 176 265 4.18E-7 T 14-10-2018 MB46_14120 a3a6b8858fce1ae159244374a0f2b24f 286 TIGRFAM TIGR00688 rarD: protein RarD 2 241 6.1E-53 T 14-10-2018 IPR004626 RarD protein GO:0005887 MB46_14120 a3a6b8858fce1ae159244374a0f2b24f 286 SUPERFAMILY SSF103481 25 125 2.62E-12 T 14-10-2018 MB46_11115 fb356e51b8d6978ea87607699910fc17 581 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 30 350 3.3E-58 T 14-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 MB46_11115 fb356e51b8d6978ea87607699910fc17 581 SUPERFAMILY SSF51445 11 390 2.74E-81 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily MB46_11115 fb356e51b8d6978ea87607699910fc17 581 Gene3D G3DSA:3.20.20.300 16 366 8.9E-80 T 14-10-2018 IPR036962 Glycoside hydrolase, family 3, N-terminal domain superfamily GO:0004553|GO:0005975 MB46_11115 fb356e51b8d6978ea87607699910fc17 581 Gene3D G3DSA:3.40.50.1700 377 571 3.2E-15 T 14-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 MB46_13035 4a72c7b97807c0b0f2388e3b78b10543 535 SUPERFAMILY SSF48592 6 521 3.51E-70 T 14-10-2018 IPR027413 GroEL-like equatorial domain superfamily MB46_13035 4a72c7b97807c0b0f2388e3b78b10543 535 Gene3D G3DSA:1.10.560.10 7 521 1.4E-215 T 14-10-2018 IPR027413 GroEL-like equatorial domain superfamily MB46_13035 4a72c7b97807c0b0f2388e3b78b10543 535 SUPERFAMILY SSF54849 141 200 1.3E-20 T 14-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily MB46_13035 4a72c7b97807c0b0f2388e3b78b10543 535 Gene3D G3DSA:3.50.7.10 189 369 1.4E-215 T 14-10-2018 IPR027409 GroEL-like apical domain superfamily MB46_13035 4a72c7b97807c0b0f2388e3b78b10543 535 TIGRFAM TIGR02348 GroEL: chaperonin GroL 2 526 8.4E-236 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MB46_13035 4a72c7b97807c0b0f2388e3b78b10543 535 SUPERFAMILY SSF52029 182 373 1.02E-78 T 14-10-2018 IPR027409 GroEL-like apical domain superfamily MB46_13035 4a72c7b97807c0b0f2388e3b78b10543 535 Hamap MF_00600 60 kDa chaperonin [groL]. 1 533 39.305 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MB46_13035 4a72c7b97807c0b0f2388e3b78b10543 535 Pfam PF00118 TCP-1/cpn60 chaperonin family 22 524 5.5E-91 T 14-10-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 MB46_13035 4a72c7b97807c0b0f2388e3b78b10543 535 Gene3D G3DSA:3.30.260.10 135 407 1.4E-215 T 14-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily MB46_13035 4a72c7b97807c0b0f2388e3b78b10543 535 PRINTS PR00298 60kDa chaperonin signature 26 52 4.6E-70 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MB46_13035 4a72c7b97807c0b0f2388e3b78b10543 535 PRINTS PR00298 60kDa chaperonin signature 395 416 4.6E-70 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MB46_13035 4a72c7b97807c0b0f2388e3b78b10543 535 PRINTS PR00298 60kDa chaperonin signature 82 109 4.6E-70 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MB46_13035 4a72c7b97807c0b0f2388e3b78b10543 535 PRINTS PR00298 60kDa chaperonin signature 265 288 4.6E-70 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MB46_13035 4a72c7b97807c0b0f2388e3b78b10543 535 PRINTS PR00298 60kDa chaperonin signature 347 372 4.6E-70 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MB46_05965 0cfb8ff053ac7e89305a33bcac797a0f 190 Pfam PF01613 Flavin reductase like domain 31 183 4.8E-29 T 14-10-2018 IPR002563 Flavin reductase like domain GO:0010181 MB46_05965 0cfb8ff053ac7e89305a33bcac797a0f 190 Gene3D G3DSA:2.30.110.10 14 188 1.1E-39 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 MB46_05965 0cfb8ff053ac7e89305a33bcac797a0f 190 SUPERFAMILY SSF50475 23 183 4.17E-37 T 14-10-2018 MB46_05965 0cfb8ff053ac7e89305a33bcac797a0f 190 SMART SM00903 31 182 3.9E-35 T 14-10-2018 IPR002563 Flavin reductase like domain GO:0010181 MB46_05405 e87cdb3ef878a8fc0c098e64f8e2c4c5 66 TIGRFAM TIGR03687 pupylate_cterm: ubiquitin-like protein Pup 35 66 3.4E-22 T 14-10-2018 IPR008515 Ubiquitin-like, Pup MB46_05405 e87cdb3ef878a8fc0c098e64f8e2c4c5 66 Hamap MF_02106 Prokaryotic ubiquitin-like protein Pup [pup]. 1 66 16.65 T 14-10-2018 IPR008515 Ubiquitin-like, Pup MB46_05405 e87cdb3ef878a8fc0c098e64f8e2c4c5 66 Pfam PF05639 Pup-like protein 3 66 3.2E-22 T 14-10-2018 IPR008515 Ubiquitin-like, Pup MB46_16775 5631e6f3b4ab84d57bf3f15d581fdfaf 403 SUPERFAMILY SSF89796 7 396 1.27E-119 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily MB46_16775 5631e6f3b4ab84d57bf3f15d581fdfaf 403 Gene3D G3DSA:3.40.50.10540 9 389 1.5E-115 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily MB46_16775 5631e6f3b4ab84d57bf3f15d581fdfaf 403 Gene3D G3DSA:3.30.1540.10 232 324 1.5E-115 T 14-10-2018 MB46_16775 5631e6f3b4ab84d57bf3f15d581fdfaf 403 Pfam PF02515 CoA-transferase family III 10 372 1.4E-117 T 14-10-2018 IPR003673 CoA-transferase family III GO:0003824 MB46_04625 2c14d03828175310c7165a7c9c1e0892 307 SMART SM00909 87 184 1.1E-5 T 14-10-2018 IPR019606 GerMN domain MB46_04625 2c14d03828175310c7165a7c9c1e0892 307 Pfam PF10646 Sporulation and spore germination 60 178 1.4E-6 T 14-10-2018 IPR019606 GerMN domain MB46_07005 6948cb32b7a0891bcab56f720243bcac 257 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 15 28 4.6E-6 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MB46_07005 6948cb32b7a0891bcab56f720243bcac 257 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 4 15 4.6E-6 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MB46_07005 6948cb32b7a0891bcab56f720243bcac 257 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 39 59 4.6E-6 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MB46_07005 6948cb32b7a0891bcab56f720243bcac 257 SMART SM00422 3 72 7.5E-15 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MB46_07005 6948cb32b7a0891bcab56f720243bcac 257 Pfam PF13411 MerR HTH family regulatory protein 4 66 3.5E-13 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MB46_07005 6948cb32b7a0891bcab56f720243bcac 257 SUPERFAMILY SSF46955 4 105 2.27E-21 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily MB46_19165 83a4a91187d25036b36249538d8dbdf1 344 Pfam PF05655 Pseudomonas avirulence D protein (AvrD) 11 332 1.3E-64 T 14-10-2018 IPR008799 Pseudomonas avirulence D MB46_19965 83a4a91187d25036b36249538d8dbdf1 344 Pfam PF05655 Pseudomonas avirulence D protein (AvrD) 11 332 1.3E-64 T 14-10-2018 IPR008799 Pseudomonas avirulence D MB46_00665 c28e38c0af5e8fbee24f79d77ee2f66e 310 SUPERFAMILY SSF111331 10 305 4.36E-58 T 14-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily MB46_00665 c28e38c0af5e8fbee24f79d77ee2f66e 310 Gene3D G3DSA:3.40.50.10330 4 141 6.5E-26 T 14-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 MB46_00665 c28e38c0af5e8fbee24f79d77ee2f66e 310 Pfam PF00781 Diacylglycerol kinase catalytic domain 26 132 2.2E-18 T 14-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 MB46_00665 c28e38c0af5e8fbee24f79d77ee2f66e 310 Gene3D G3DSA:2.60.200.40 142 298 4.2E-36 T 14-10-2018 MB46_14415 6d848d8cef0055f15ae4774fbe1c2c62 260 Pfam PF00378 Enoyl-CoA hydratase/isomerase 7 259 2.5E-38 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 MB46_14415 6d848d8cef0055f15ae4774fbe1c2c62 260 SUPERFAMILY SSF52096 4 259 2.95E-58 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MB46_14415 6d848d8cef0055f15ae4774fbe1c2c62 260 Gene3D G3DSA:1.10.12.10 201 260 9.2E-14 T 14-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal MB46_14415 6d848d8cef0055f15ae4774fbe1c2c62 260 Gene3D G3DSA:3.90.226.10 1 199 3.1E-48 T 14-10-2018 MB46_00795 0ce2ffc29dfb5e166fccb8324b1257e6 374 SUPERFAMILY SSF50129 11 200 1.62E-54 T 14-10-2018 IPR011032 GroES-like superfamily MB46_00795 0ce2ffc29dfb5e166fccb8324b1257e6 374 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 35 157 1.9E-25 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MB46_00795 0ce2ffc29dfb5e166fccb8324b1257e6 374 Pfam PF00107 Zinc-binding dehydrogenase 204 324 6.5E-20 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 MB46_00795 0ce2ffc29dfb5e166fccb8324b1257e6 374 Gene3D G3DSA:3.90.180.10 19 367 2.1E-109 T 14-10-2018 MB46_00795 0ce2ffc29dfb5e166fccb8324b1257e6 374 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 67 81 - T 14-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 MB46_00795 0ce2ffc29dfb5e166fccb8324b1257e6 374 Gene3D G3DSA:3.40.50.720 181 315 2.1E-109 T 14-10-2018 MB46_00795 0ce2ffc29dfb5e166fccb8324b1257e6 374 SUPERFAMILY SSF51735 166 337 2.63E-35 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_00795 0ce2ffc29dfb5e166fccb8324b1257e6 374 SMART SM00829 17 366 1.3E-4 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MB46_13290 359d47ae5288ce5f85b9f81f444fb7d5 125 SUPERFAMILY SSF46946 2 122 1.83E-44 T 14-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 MB46_13290 359d47ae5288ce5f85b9f81f444fb7d5 125 PIRSF PIRSF002134 1 125 5.0E-43 T 14-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MB46_13290 359d47ae5288ce5f85b9f81f444fb7d5 125 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 115 5.3E-51 T 14-10-2018 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 MB46_13290 359d47ae5288ce5f85b9f81f444fb7d5 125 Pfam PF00416 Ribosomal protein S13/S18 3 109 2.7E-31 T 14-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MB46_13290 359d47ae5288ce5f85b9f81f444fb7d5 125 ProSitePatterns PS00646 Ribosomal protein S13 signature. 88 101 - T 14-10-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MB46_13290 359d47ae5288ce5f85b9f81f444fb7d5 125 Gene3D G3DSA:4.10.910.10 73 125 7.7E-24 T 14-10-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MB46_13290 359d47ae5288ce5f85b9f81f444fb7d5 125 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 119 26.224 T 14-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MB46_13290 359d47ae5288ce5f85b9f81f444fb7d5 125 Gene3D G3DSA:1.10.8.50 1 72 6.6E-31 T 14-10-2018 MB46_15195 cf64bfaed180a510a71267f8752b838e 283 Gene3D G3DSA:3.40.50.150 20 283 5.7E-70 T 14-10-2018 MB46_15195 cf64bfaed180a510a71267f8752b838e 283 SUPERFAMILY SSF53335 41 244 1.77E-26 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MB46_16785 79da96914a0e9a9dbd1dd26bb805863d 255 SUPERFAMILY SSF51735 4 250 3.36E-55 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_16785 79da96914a0e9a9dbd1dd26bb805863d 255 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 147 175 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MB46_16785 79da96914a0e9a9dbd1dd26bb805863d 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 4.2E-23 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_16785 79da96914a0e9a9dbd1dd26bb805863d 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 4.2E-23 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_16785 79da96914a0e9a9dbd1dd26bb805863d 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 4.2E-23 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_16785 79da96914a0e9a9dbd1dd26bb805863d 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 4.2E-23 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_16785 79da96914a0e9a9dbd1dd26bb805863d 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 4.2E-23 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_16785 79da96914a0e9a9dbd1dd26bb805863d 255 Pfam PF00106 short chain dehydrogenase 9 201 1.6E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_16785 79da96914a0e9a9dbd1dd26bb805863d 255 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 191 0.0042 T 14-10-2018 MB46_16785 79da96914a0e9a9dbd1dd26bb805863d 255 Gene3D G3DSA:3.40.50.720 1 255 5.8E-63 T 14-10-2018 MB46_15375 992bb399ed5f2f6b30cca0b666fc3521 302 SUPERFAMILY SSF48150 3 217 1.57E-66 T 14-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 MB46_15375 992bb399ed5f2f6b30cca0b666fc3521 302 ProSitePatterns PS01155 Endonuclease III family signature. 96 125 - T 14-10-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 MB46_15375 992bb399ed5f2f6b30cca0b666fc3521 302 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 187 203 - T 14-10-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 MB46_15375 992bb399ed5f2f6b30cca0b666fc3521 302 SMART SM00478 33 185 1.6E-41 T 14-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 MB46_15375 992bb399ed5f2f6b30cca0b666fc3521 302 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 29 158 2.0E-16 T 14-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 MB46_15375 992bb399ed5f2f6b30cca0b666fc3521 302 SMART SM00525 186 206 1.8E-4 T 14-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 MB46_15375 992bb399ed5f2f6b30cca0b666fc3521 302 Pfam PF00633 Helix-hairpin-helix motif 94 122 1.5E-8 T 14-10-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 MB46_15375 992bb399ed5f2f6b30cca0b666fc3521 302 Pfam PF10576 Iron-sulfur binding domain of endonuclease III 187 203 2.7E-5 T 14-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 MB46_15375 992bb399ed5f2f6b30cca0b666fc3521 302 Gene3D G3DSA:1.10.1670.10 4 206 5.5E-71 T 14-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 MB46_15375 992bb399ed5f2f6b30cca0b666fc3521 302 Gene3D G3DSA:1.10.340.30 15 126 5.5E-71 T 14-10-2018 MB46_09320 f4d10f0e0bcf82b43824b4ff605d8cea 426 Pfam PF09594 Glycosyltransferase family 87 77 317 4.6E-12 T 14-10-2018 IPR018584 Glycosyltransferase family 87 GO:0016758 MB46_00515 6a404809484ac8bbe026079bee50a3ad 479 ProSitePatterns PS00218 Amino acid permeases signature. 56 87 - T 14-10-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 MB46_00515 6a404809484ac8bbe026079bee50a3ad 479 PIRSF PIRSF006060 7 479 2.5E-76 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 MB46_00515 6a404809484ac8bbe026079bee50a3ad 479 Pfam PF00324 Amino acid permease 31 468 1.5E-114 T 14-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 MB46_00515 6a404809484ac8bbe026079bee50a3ad 479 Gene3D G3DSA:1.20.1740.10 23 479 1.6E-63 T 14-10-2018 MB46_02905 fe666fe0d2e0d0429441441e75ed23f2 968 Pfam PF00196 Bacterial regulatory proteins, luxR family 909 963 1.8E-16 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_02905 fe666fe0d2e0d0429441441e75ed23f2 968 SUPERFAMILY SSF46894 899 965 3.23E-18 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MB46_02905 fe666fe0d2e0d0429441441e75ed23f2 968 Pfam PF13191 AAA ATPase domain 13 160 9.9E-16 T 14-10-2018 MB46_02905 fe666fe0d2e0d0429441441e75ed23f2 968 Gene3D G3DSA:1.25.40.10 522 886 1.9E-5 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MB46_02905 fe666fe0d2e0d0429441441e75ed23f2 968 ProSitePatterns PS00622 LuxR-type HTH domain signature. 923 950 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_02905 fe666fe0d2e0d0429441441e75ed23f2 968 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 909 923 1.3E-10 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_02905 fe666fe0d2e0d0429441441e75ed23f2 968 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 923 939 1.3E-10 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_02905 fe666fe0d2e0d0429441441e75ed23f2 968 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 939 951 1.3E-10 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_02905 fe666fe0d2e0d0429441441e75ed23f2 968 SMART SM00421 906 963 7.0E-23 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_02905 fe666fe0d2e0d0429441441e75ed23f2 968 Gene3D G3DSA:1.10.10.10 887 966 6.0E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_02905 fe666fe0d2e0d0429441441e75ed23f2 968 SUPERFAMILY SSF52540 11 194 2.13E-8 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_02905 fe666fe0d2e0d0429441441e75ed23f2 968 Gene3D G3DSA:3.40.50.300 4 174 5.3E-6 T 14-10-2018 MB46_08905 3db48803fc83449cc05fc9f61c8a3fb9 253 Gene3D G3DSA:1.10.10.10 11 85 9.6E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_08905 3db48803fc83449cc05fc9f61c8a3fb9 253 SUPERFAMILY SSF46785 11 85 7.75E-13 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_08905 3db48803fc83449cc05fc9f61c8a3fb9 253 SUPERFAMILY SSF48008 104 238 2.88E-22 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MB46_08905 3db48803fc83449cc05fc9f61c8a3fb9 253 SMART SM00345 18 81 2.9E-8 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MB46_08905 3db48803fc83449cc05fc9f61c8a3fb9 253 SMART SM00895 106 233 2.7E-14 T 14-10-2018 IPR011711 GntR, C-terminal MB46_08905 3db48803fc83449cc05fc9f61c8a3fb9 253 Pfam PF07729 FCD domain 106 232 1.3E-18 T 14-10-2018 IPR011711 GntR, C-terminal MB46_08905 3db48803fc83449cc05fc9f61c8a3fb9 253 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 74 7.6E-12 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MB46_08905 3db48803fc83449cc05fc9f61c8a3fb9 253 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 37 51 7.6E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MB46_08905 3db48803fc83449cc05fc9f61c8a3fb9 253 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 51 67 7.6E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MB46_08905 3db48803fc83449cc05fc9f61c8a3fb9 253 Gene3D G3DSA:1.20.120.530 87 241 1.7E-30 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MB46_09840 16e28f6c217d6140c5c3aa37fe43e588 287 Gene3D G3DSA:1.10.260.40 27 93 1.6E-9 T 14-10-2018 MB46_09840 16e28f6c217d6140c5c3aa37fe43e588 287 SUPERFAMILY SSF47413 32 79 1.36E-9 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MB46_09840 16e28f6c217d6140c5c3aa37fe43e588 287 SMART SM00530 11 83 1.7E-8 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MB46_09840 16e28f6c217d6140c5c3aa37fe43e588 287 Pfam PF13560 Helix-turn-helix domain 7 86 1.3E-13 T 14-10-2018 MB46_06105 1ababc57e2a70fa6473a540f87954df4 600 SUPERFAMILY SSF52540 8 255 7.29E-61 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_06105 1ababc57e2a70fa6473a540f87954df4 600 Gene3D G3DSA:3.40.50.300 6 316 3.0E-79 T 14-10-2018 MB46_06105 1ababc57e2a70fa6473a540f87954df4 600 Gene3D G3DSA:3.40.50.300 326 598 3.0E-88 T 14-10-2018 MB46_06105 1ababc57e2a70fa6473a540f87954df4 600 ProSitePatterns PS00211 ABC transporters family signature. 479 493 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_06105 1ababc57e2a70fa6473a540f87954df4 600 Pfam PF00005 ABC transporter 25 184 3.6E-27 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_06105 1ababc57e2a70fa6473a540f87954df4 600 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 558 588 8.5E-6 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MB46_06105 1ababc57e2a70fa6473a540f87954df4 600 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 236 268 7.1E-5 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MB46_06105 1ababc57e2a70fa6473a540f87954df4 600 Pfam PF00005 ABC transporter 354 506 2.5E-31 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_06105 1ababc57e2a70fa6473a540f87954df4 600 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_06105 1ababc57e2a70fa6473a540f87954df4 600 SUPERFAMILY SSF52540 328 578 3.76E-73 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_06105 1ababc57e2a70fa6473a540f87954df4 600 SMART SM00382 33 234 1.1E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_06105 1ababc57e2a70fa6473a540f87954df4 600 SMART SM00382 363 556 1.3E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_12580 b370cdbd5f23b0e932cec4e36018f60f 346 SUPERFAMILY SSF51679 14 334 3.01E-53 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 MB46_12580 b370cdbd5f23b0e932cec4e36018f60f 346 Gene3D G3DSA:3.20.20.30 16 337 1.4E-50 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 MB46_12580 b370cdbd5f23b0e932cec4e36018f60f 346 Pfam PF00296 Luciferase-like monooxygenase 27 302 8.0E-29 T 14-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MB46_12060 c1e5ef716c6a85b69b577bfd99f4e1f9 450 SUPERFAMILY SSF69742 4 158 4.97E-29 T 14-10-2018 IPR036343 Glutamyl-tRNA reductase, N-terminal domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 MB46_12060 c1e5ef716c6a85b69b577bfd99f4e1f9 450 Gene3D G3DSA:3.40.50.720 163 328 4.6E-26 T 14-10-2018 MB46_12060 c1e5ef716c6a85b69b577bfd99f4e1f9 450 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 2 429 18.957 T 14-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 MB46_12060 c1e5ef716c6a85b69b577bfd99f4e1f9 450 ProSitePatterns PS00747 Glutamyl-tRNA reductase signature. 100 123 - T 14-10-2018 IPR018214 Glutamyl-tRNA reductase, conserved site GO:0008883|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 MB46_12060 c1e5ef716c6a85b69b577bfd99f4e1f9 450 Pfam PF00745 Glutamyl-tRNAGlu reductase, dimerisation domain 332 429 4.2E-16 T 14-10-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 MB46_12060 c1e5ef716c6a85b69b577bfd99f4e1f9 450 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 8 157 6.6E-31 T 14-10-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 MB46_12060 c1e5ef716c6a85b69b577bfd99f4e1f9 450 Gene3D G3DSA:3.30.460.30 2 159 7.6E-36 T 14-10-2018 IPR036343 Glutamyl-tRNA reductase, N-terminal domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 MB46_12060 c1e5ef716c6a85b69b577bfd99f4e1f9 450 SUPERFAMILY SSF69075 331 429 5.1E-11 T 14-10-2018 IPR036453 Glutamyl tRNA-reductase dimerization domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 MB46_12060 c1e5ef716c6a85b69b577bfd99f4e1f9 450 PIRSF PIRSF000445 1 440 3.4E-88 T 14-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 MB46_12060 c1e5ef716c6a85b69b577bfd99f4e1f9 450 SUPERFAMILY SSF51735 186 362 3.1E-9 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_12060 c1e5ef716c6a85b69b577bfd99f4e1f9 450 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 195 319 8.8E-7 T 14-10-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase MB46_01080 9720a68ecd5830da615ceaa29a60e3c7 389 Hamap MF_00558 Succinate--CoA ligase [ADP-forming] subunit beta [sucC]. 1 386 38.798 T 14-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 MB46_01080 9720a68ecd5830da615ceaa29a60e3c7 389 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 249 273 - T 14-10-2018 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MB46_01080 9720a68ecd5830da615ceaa29a60e3c7 389 Pfam PF00549 CoA-ligase 256 374 3.9E-14 T 14-10-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MB46_01080 9720a68ecd5830da615ceaa29a60e3c7 389 SUPERFAMILY SSF56059 3 227 4.42E-65 T 14-10-2018 MB46_01080 9720a68ecd5830da615ceaa29a60e3c7 389 Gene3D G3DSA:3.30.1490.20 21 96 3.2E-78 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 MB46_01080 9720a68ecd5830da615ceaa29a60e3c7 389 SUPERFAMILY SSF52210 231 385 6.28E-42 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MB46_01080 9720a68ecd5830da615ceaa29a60e3c7 389 Gene3D G3DSA:3.30.470.20 2 226 3.2E-78 T 14-10-2018 MB46_01080 9720a68ecd5830da615ceaa29a60e3c7 389 Pfam PF08442 ATP-grasp domain 2 194 2.1E-68 T 14-10-2018 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 MB46_01080 9720a68ecd5830da615ceaa29a60e3c7 389 PIRSF PIRSF001554 1 388 3.5E-137 T 14-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 MB46_01080 9720a68ecd5830da615ceaa29a60e3c7 389 Gene3D G3DSA:3.40.50.261 232 388 1.2E-47 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MB46_01080 9720a68ecd5830da615ceaa29a60e3c7 389 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 2 385 1.2E-125 T 14-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 MB46_14680 955c62f274d1f7b73604d416fc3ed854 1015 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 213 335 5.1E-13 T 14-10-2018 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 MB46_14680 955c62f274d1f7b73604d416fc3ed854 1015 SUPERFAMILY SSF48019 221 336 7.4E-19 T 14-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 MB46_14680 955c62f274d1f7b73604d416fc3ed854 1015 Pfam PF13177 DNA polymerase III, delta subunit 3 150 2.2E-35 T 14-10-2018 MB46_14680 955c62f274d1f7b73604d416fc3ed854 1015 SUPERFAMILY SSF52540 6 195 4.61E-52 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_14680 955c62f274d1f7b73604d416fc3ed854 1015 SMART SM00382 9 157 3.0E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_14680 955c62f274d1f7b73604d416fc3ed854 1015 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 2 331 4.7E-104 T 14-10-2018 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 MB46_14680 955c62f274d1f7b73604d416fc3ed854 1015 Gene3D G3DSA:3.40.50.300 2 151 1.9E-84 T 14-10-2018 MB46_14680 955c62f274d1f7b73604d416fc3ed854 1015 Gene3D G3DSA:1.20.272.10 217 338 7.6E-5 T 14-10-2018 MB46_14680 955c62f274d1f7b73604d416fc3ed854 1015 Gene3D G3DSA:1.10.8.60 152 202 1.9E-84 T 14-10-2018 MB46_13270 6dcf5e8d51feda579986d21b4d039a78 300 Pfam PF01416 tRNA pseudouridine synthase 174 276 1.3E-20 T 14-10-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 MB46_13270 6dcf5e8d51feda579986d21b4d039a78 300 PIRSF PIRSF001430 14 291 6.5E-65 T 14-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 MB46_13270 6dcf5e8d51feda579986d21b4d039a78 300 Gene3D G3DSA:3.30.70.580 12 135 2.3E-29 T 14-10-2018 MB46_13270 6dcf5e8d51feda579986d21b4d039a78 300 Gene3D G3DSA:3.30.70.660 136 278 1.1E-34 T 14-10-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0003723|GO:0009982 MB46_13270 6dcf5e8d51feda579986d21b4d039a78 300 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 14 275 29.743 T 14-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 MB46_13270 6dcf5e8d51feda579986d21b4d039a78 300 SUPERFAMILY SSF55120 14 285 8.34E-64 T 14-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 MB46_18460 4d9f29049a8aa6c9cbb6a36c99bba1cf 64 Pfam PF05532 CsbD-like 5 57 9.6E-15 T 14-10-2018 IPR008462 CsbD-like domain MB46_18460 4d9f29049a8aa6c9cbb6a36c99bba1cf 64 SUPERFAMILY SSF69047 4 63 3.92E-7 T 14-10-2018 IPR036629 YjbJ superfamily MB46_09440 c54c7c39956e7cee6c18535483c80995 300 Gene3D G3DSA:3.40.50.10190 190 298 3.7E-15 T 14-10-2018 IPR036420 BRCT domain superfamily MB46_09440 c54c7c39956e7cee6c18535483c80995 300 SMART SM00479 5 171 1.3E-4 T 14-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III MB46_09440 c54c7c39956e7cee6c18535483c80995 300 SUPERFAMILY SSF52113 212 298 8.5E-9 T 14-10-2018 IPR036420 BRCT domain superfamily MB46_09440 c54c7c39956e7cee6c18535483c80995 300 SUPERFAMILY SSF53098 4 168 5.25E-30 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily MB46_09440 c54c7c39956e7cee6c18535483c80995 300 Pfam PF00929 Exonuclease 9 161 8.4E-7 T 14-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III MB46_09440 c54c7c39956e7cee6c18535483c80995 300 Gene3D G3DSA:3.30.420.10 4 173 9.1E-27 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 MB46_05835 6f8ab55695cb03a04f725210f9912825 205 Hamap MF_01389 Urease accessory protein UreG [ureG]. 2 200 44.347 T 14-10-2018 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 MB46_05835 6f8ab55695cb03a04f725210f9912825 205 SUPERFAMILY SSF52540 3 195 3.09E-31 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_05835 6f8ab55695cb03a04f725210f9912825 205 Gene3D G3DSA:3.40.50.300 4 200 4.7E-46 T 14-10-2018 MB46_05835 6f8ab55695cb03a04f725210f9912825 205 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 6 170 2.2E-35 T 14-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain MB46_05835 6f8ab55695cb03a04f725210f9912825 205 PIRSF PIRSF005624 2 203 2.6E-45 T 14-10-2018 IPR012202 [NiFe]-hydrogenase/urease maturation factor, Ni2-binding GTPase GO:0003924|GO:0016151 MB46_05835 6f8ab55695cb03a04f725210f9912825 205 TIGRFAM TIGR00101 ureG: urease accessory protein UreG 4 199 2.3E-91 T 14-10-2018 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 MB46_02380 5f3e9811c52276ceda9440e9aa3c42ed 570 Pfam PF16192 C-terminal four TMM region of protein-O-mannosyltransferase 379 569 1.0E-17 T 14-10-2018 IPR032421 Protein O-mannosyl-transferase, C-terminal four TM domain KEGG: 00514+2.4.1.109|KEGG: 00515+2.4.1.109|MetaCyc: PWY-7921|MetaCyc: PWY-7922|MetaCyc: PWY-7979|Reactome: R-HSA-5173105 MB46_02380 5f3e9811c52276ceda9440e9aa3c42ed 570 Pfam PF02366 Dolichyl-phosphate-mannose-protein mannosyltransferase 81 232 8.7E-11 T 14-10-2018 IPR003342 Glycosyl transferase family 39/83 GO:0000030|GO:0006493|GO:0016020 Reactome: R-HSA-5173105 MB46_16980 e2291b93f6acfc3581c4efb321d53524 265 Pfam PF02361 Cobalt transport protein 13 221 1.8E-18 T 14-10-2018 IPR003339 ABC/ECF transporter, transmembrane component MB46_12790 1202494a5a3077bf038fad390efb3f2c 744 SUPERFAMILY SSF82866 508 719 2.88E-27 T 14-10-2018 MB46_12790 1202494a5a3077bf038fad390efb3f2c 744 Gene3D G3DSA:1.20.1640.10 170 361 1.3E-14 T 14-10-2018 MB46_12790 1202494a5a3077bf038fad390efb3f2c 744 Gene3D G3DSA:1.20.1640.10 554 707 1.5E-6 T 14-10-2018 MB46_12790 1202494a5a3077bf038fad390efb3f2c 744 Pfam PF03176 MMPL family 458 720 2.2E-51 T 14-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 MB46_12790 1202494a5a3077bf038fad390efb3f2c 744 Pfam PF03176 MMPL family 49 398 6.0E-64 T 14-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 MB46_12790 1202494a5a3077bf038fad390efb3f2c 744 Gene3D G3DSA:3.30.70.1440 500 553 1.5E-6 T 14-10-2018 MB46_12790 1202494a5a3077bf038fad390efb3f2c 744 SUPERFAMILY SSF82866 143 344 1.22E-31 T 14-10-2018 MB46_12235 45b5309eefb325c83008a969d94269cd 256 SUPERFAMILY SSF51730 5 249 1.16E-43 T 14-10-2018 IPR029041 FAD-linked oxidoreductase-like MB46_12235 45b5309eefb325c83008a969d94269cd 256 Gene3D G3DSA:3.20.20.220 6 254 4.9E-33 T 14-10-2018 MB46_12235 45b5309eefb325c83008a969d94269cd 256 Pfam PF02219 Methylenetetrahydrofolate reductase 43 181 2.1E-17 T 14-10-2018 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 MB46_12555 cdfdaeeb7c663a229e23bcd2f2f023fd 604 PIRSF PIRSF002741 5 220 1.8E-12 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 MB46_12555 cdfdaeeb7c663a229e23bcd2f2f023fd 604 PIRSF PIRSF002741 247 603 4.2E-28 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 MB46_12555 cdfdaeeb7c663a229e23bcd2f2f023fd 604 SUPERFAMILY SSF53850 39 599 7.06E-57 T 14-10-2018 MB46_12555 cdfdaeeb7c663a229e23bcd2f2f023fd 604 Gene3D G3DSA:3.40.190.10 13 348 7.6E-32 T 14-10-2018 MB46_12555 cdfdaeeb7c663a229e23bcd2f2f023fd 604 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 99 513 7.2E-37 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain MB46_12555 cdfdaeeb7c663a229e23bcd2f2f023fd 604 Gene3D G3DSA:3.10.105.10 352 571 1.2E-26 T 14-10-2018 MB46_14530 8bb611e2c7422d2cecdebd3aa520977d 330 Gene3D G3DSA:1.10.3720.10 80 323 2.0E-58 T 14-10-2018 IPR035906 MetI-like superfamily MB46_14530 8bb611e2c7422d2cecdebd3aa520977d 330 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 116 267 3.0E-14 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_14530 8bb611e2c7422d2cecdebd3aa520977d 330 SUPERFAMILY SSF161098 84 311 8.11E-51 T 14-10-2018 IPR035906 MetI-like superfamily MB46_17050 cd26d41e14aaf8d3873a97bba51c54bf 694 Gene3D G3DSA:3.60.120.10 225 691 8.1E-133 T 14-10-2018 IPR005801 ADC synthase GO:0009058 MB46_17050 cd26d41e14aaf8d3873a97bba51c54bf 694 PRINTS PR00095 Anthranilate synthase component I signature 617 631 8.2E-14 T 14-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MB46_17050 cd26d41e14aaf8d3873a97bba51c54bf 694 PRINTS PR00095 Anthranilate synthase component I signature 632 646 8.2E-14 T 14-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MB46_17050 cd26d41e14aaf8d3873a97bba51c54bf 694 PRINTS PR00095 Anthranilate synthase component I signature 523 536 8.2E-14 T 14-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MB46_17050 cd26d41e14aaf8d3873a97bba51c54bf 694 PRINTS PR00095 Anthranilate synthase component I signature 537 550 8.2E-14 T 14-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MB46_17050 cd26d41e14aaf8d3873a97bba51c54bf 694 TIGRFAM TIGR00553 pabB: aminodeoxychorismate synthase, component I 316 681 1.0E-99 T 14-10-2018 IPR005802 Para-aminobenzoate synthase, component I GO:0009396 KEGG: 00790+2.6.1.85|MetaCyc: PWY-6543 MB46_17050 cd26d41e14aaf8d3873a97bba51c54bf 694 SUPERFAMILY SSF52540 4 164 1.84E-16 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_17050 cd26d41e14aaf8d3873a97bba51c54bf 694 Pfam PF04715 Anthranilate synthase component I, N terminal region 217 361 2.4E-10 T 14-10-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MB46_17050 cd26d41e14aaf8d3873a97bba51c54bf 694 Pfam PF00425 chorismate binding enzyme 419 680 2.9E-86 T 14-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal MB46_17050 cd26d41e14aaf8d3873a97bba51c54bf 694 SUPERFAMILY SSF56322 212 689 2.09E-110 T 14-10-2018 IPR005801 ADC synthase GO:0009058 MB46_17050 cd26d41e14aaf8d3873a97bba51c54bf 694 Gene3D G3DSA:3.40.50.300 2 168 2.6E-28 T 14-10-2018 MB46_00640 88e9c6946b3ba85c32c036d53431f441 549 Pfam PF00916 Sulfate permease family 26 386 3.2E-73 T 14-10-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 MB46_00640 88e9c6946b3ba85c32c036d53431f441 549 Gene3D G3DSA:3.30.750.24 419 546 1.8E-24 T 14-10-2018 IPR036513 STAS domain superfamily MB46_00640 88e9c6946b3ba85c32c036d53431f441 549 Pfam PF01740 STAS domain 431 517 7.4E-16 T 14-10-2018 IPR002645 STAS domain MB46_00640 88e9c6946b3ba85c32c036d53431f441 549 SUPERFAMILY SSF52091 434 536 2.75E-15 T 14-10-2018 IPR036513 STAS domain superfamily MB46_03330 06bd2811bedc8f40b32a65e94b0b95b6 346 SUPERFAMILY SSF50129 7 157 3.14E-12 T 14-10-2018 IPR011032 GroES-like superfamily MB46_03330 06bd2811bedc8f40b32a65e94b0b95b6 346 SUPERFAMILY SSF51735 126 268 3.22E-15 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_03330 06bd2811bedc8f40b32a65e94b0b95b6 346 Gene3D G3DSA:3.90.180.10 7 320 2.8E-23 T 14-10-2018 MB46_03500 fefeeb693e7c6b9a2c4ea2a4b8fac4fb 251 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 21 250 5.7E-90 T 14-10-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 MB46_03500 fefeeb693e7c6b9a2c4ea2a4b8fac4fb 251 Pfam PF00696 Amino acid kinase family 22 228 3.4E-28 T 14-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 MB46_03500 fefeeb693e7c6b9a2c4ea2a4b8fac4fb 251 Hamap MF_01220_B Uridylate kinase [pyrH]. 18 250 42.167 T 14-10-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 MB46_03500 fefeeb693e7c6b9a2c4ea2a4b8fac4fb 251 Gene3D G3DSA:3.40.1160.10 14 251 1.3E-72 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily MB46_03500 fefeeb693e7c6b9a2c4ea2a4b8fac4fb 251 PIRSF PIRSF005650 16 251 1.0E-87 T 14-10-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 MB46_03500 fefeeb693e7c6b9a2c4ea2a4b8fac4fb 251 SUPERFAMILY SSF53633 19 251 3.14E-68 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily MB46_12655 87233e256819216452d527a673fe4281 361 Gene3D G3DSA:3.40.50.11270 44 128 1.1E-106 T 14-10-2018 MB46_12655 87233e256819216452d527a673fe4281 361 Gene3D G3DSA:3.40.1010.20 39 311 1.1E-106 T 14-10-2018 MB46_12655 87233e256819216452d527a673fe4281 361 Pfam PF02401 LytB protein 35 312 7.0E-88 T 14-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 MB46_12655 87233e256819216452d527a673fe4281 361 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 35 313 4.1E-97 T 14-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 MB46_12655 87233e256819216452d527a673fe4281 361 Gene3D G3DSA:3.40.1010.20 129 225 1.1E-106 T 14-10-2018 MB46_12655 87233e256819216452d527a673fe4281 361 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 33 316 36.11 T 14-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 MB46_01770 3dbf8f3ec42f4b9dba7b6b0375b6fe4b 172 Gene3D G3DSA:2.160.10.10 3 171 1.3E-57 T 14-10-2018 MB46_01770 3dbf8f3ec42f4b9dba7b6b0375b6fe4b 172 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 89 122 1.8E-7 T 14-10-2018 IPR001451 Hexapeptide repeat MB46_01770 3dbf8f3ec42f4b9dba7b6b0375b6fe4b 172 SUPERFAMILY SSF51161 6 167 1.18E-44 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily MB46_08135 2511bf7dae0b7a0fb06abd9cc5026297 1020 Gene3D G3DSA:3.30.460.100 621 860 1.5E-52 T 14-10-2018 MB46_08135 2511bf7dae0b7a0fb06abd9cc5026297 1020 Gene3D G3DSA:3.30.460.100 90 347 4.2E-59 T 14-10-2018 MB46_08135 2511bf7dae0b7a0fb06abd9cc5026297 1020 SUPERFAMILY SSF81593 869 1019 1.26E-34 T 14-10-2018 MB46_08135 2511bf7dae0b7a0fb06abd9cc5026297 1020 Pfam PF08335 GlnD PII-uridylyltransferase 363 507 2.6E-33 T 14-10-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 MB46_08135 2511bf7dae0b7a0fb06abd9cc5026297 1020 Pfam PF08335 GlnD PII-uridylyltransferase 877 1018 9.5E-21 T 14-10-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 MB46_08135 2511bf7dae0b7a0fb06abd9cc5026297 1020 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 612 854 1.2E-42 T 14-10-2018 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 MB46_08135 2511bf7dae0b7a0fb06abd9cc5026297 1020 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 81 342 1.5E-43 T 14-10-2018 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 MB46_08135 2511bf7dae0b7a0fb06abd9cc5026297 1020 SUPERFAMILY SSF81301 57 349 3.6E-54 T 14-10-2018 MB46_08135 2511bf7dae0b7a0fb06abd9cc5026297 1020 Gene3D G3DSA:1.20.120.330 355 509 5.0E-42 T 14-10-2018 MB46_08135 2511bf7dae0b7a0fb06abd9cc5026297 1020 Gene3D G3DSA:1.20.120.330 864 1019 4.9E-37 T 14-10-2018 MB46_08135 2511bf7dae0b7a0fb06abd9cc5026297 1020 SUPERFAMILY SSF81593 355 508 1.18E-36 T 14-10-2018 MB46_08135 2511bf7dae0b7a0fb06abd9cc5026297 1020 SUPERFAMILY SSF81301 584 864 7.85E-58 T 14-10-2018 MB46_09880 39aecead3002606c67a673d3a8269fdb 690 Gene3D G3DSA:1.10.3470.10 366 690 5.4E-87 T 14-10-2018 IPR037294 ABC transporter, BtuC-like MB46_09880 39aecead3002606c67a673d3a8269fdb 690 Gene3D G3DSA:1.10.3470.10 15 352 5.3E-72 T 14-10-2018 IPR037294 ABC transporter, BtuC-like MB46_09880 39aecead3002606c67a673d3a8269fdb 690 SUPERFAMILY SSF81345 365 687 5.75E-74 T 14-10-2018 IPR037294 ABC transporter, BtuC-like MB46_09880 39aecead3002606c67a673d3a8269fdb 690 SUPERFAMILY SSF81345 19 347 3.66E-51 T 14-10-2018 IPR037294 ABC transporter, BtuC-like MB46_09880 39aecead3002606c67a673d3a8269fdb 690 Pfam PF01032 FecCD transport family 380 687 1.4E-82 T 14-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 MB46_09880 39aecead3002606c67a673d3a8269fdb 690 Pfam PF01032 FecCD transport family 28 347 3.5E-63 T 14-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 MB46_10720 e182b2e4055eb994ef4d018744debc94 246 Pfam PF03725 3' exoribonuclease family, domain 2 166 230 3.2E-10 T 14-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MB46_10720 e182b2e4055eb994ef4d018744debc94 246 ProSitePatterns PS01277 Ribonuclease PH signature. 122 135 - T 14-10-2018 IPR018336 Ribonuclease PH, conserved site MB46_10720 e182b2e4055eb994ef4d018744debc94 246 Pfam PF01138 3' exoribonuclease family, domain 1 16 146 1.4E-23 T 14-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MB46_10720 e182b2e4055eb994ef4d018744debc94 246 SUPERFAMILY SSF55666 161 244 1.57E-23 T 14-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MB46_10720 e182b2e4055eb994ef4d018744debc94 246 Gene3D G3DSA:3.30.230.70 16 246 2.0E-59 T 14-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MB46_10720 e182b2e4055eb994ef4d018744debc94 246 SUPERFAMILY SSF54211 5 188 7.59E-46 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MB46_10720 e182b2e4055eb994ef4d018744debc94 246 Hamap MF_00564 Ribonuclease PH [rph]. 17 245 42.975 T 14-10-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 MB46_10720 e182b2e4055eb994ef4d018744debc94 246 TIGRFAM TIGR01966 RNasePH: ribonuclease PH 8 244 3.6E-111 T 14-10-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 MB46_12030 764703ff2afdbacb64bf062c478830bf 322 Gene3D G3DSA:3.40.50.10090 54 189 7.6E-21 T 14-10-2018 MB46_12030 764703ff2afdbacb64bf062c478830bf 322 SUPERFAMILY SSF69618 20 314 5.67E-40 T 14-10-2018 IPR036108 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase superfamily GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MB46_12030 764703ff2afdbacb64bf062c478830bf 322 Pfam PF02602 Uroporphyrinogen-III synthase HemD 33 310 7.9E-44 T 14-10-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MB46_12030 764703ff2afdbacb64bf062c478830bf 322 Gene3D G3DSA:3.40.50.10090 226 318 1.5E-10 T 14-10-2018 MB46_04635 3a952e727ce3f479294a237fb08f497c 157 Gene3D G3DSA:3.40.390.30 1 153 1.2E-37 T 14-10-2018 IPR023091 Metalloprotease catalytic domain superfamily, predicted GO:0004222 MB46_04635 3a952e727ce3f479294a237fb08f497c 157 ProSitePatterns PS01306 Uncharacterized protein family UPF0054 signature. 116 126 - T 14-10-2018 IPR020549 Endoribonuclease YbeY, conserved site MB46_04635 3a952e727ce3f479294a237fb08f497c 157 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 36 145 2.4E-31 T 14-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 MB46_04635 3a952e727ce3f479294a237fb08f497c 157 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 2 151 21.86 T 14-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 MB46_04635 3a952e727ce3f479294a237fb08f497c 157 Pfam PF02130 Uncharacterized protein family UPF0054 15 145 1.1E-37 T 14-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 MB46_04635 3a952e727ce3f479294a237fb08f497c 157 SUPERFAMILY SSF55486 3 145 5.37E-38 T 14-10-2018 MB46_12045 99cdf6a8c9a68e05529050bfcfd96083 231 Pfam PF06778 Chlorite dismutase 35 221 5.1E-65 T 14-10-2018 IPR010644 Putative heme-dependent peroxidase/Chlorite dismutase MB46_12045 99cdf6a8c9a68e05529050bfcfd96083 231 SUPERFAMILY SSF54909 9 230 1.53E-67 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel MB46_12045 99cdf6a8c9a68e05529050bfcfd96083 231 Gene3D G3DSA:3.30.70.1100 114 231 1.1E-35 T 14-10-2018 MB46_03935 07a158aae934fb9d6fa46a2fce5c97b4 305 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 11 305 25.787 T 14-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 MB46_03935 07a158aae934fb9d6fa46a2fce5c97b4 305 Gene3D G3DSA:3.10.310.10 10 154 1.6E-42 T 14-10-2018 MB46_03935 07a158aae934fb9d6fa46a2fce5c97b4 305 SUPERFAMILY SSF54506 11 148 2.27E-33 T 14-10-2018 MB46_03935 07a158aae934fb9d6fa46a2fce5c97b4 305 ProSitePatterns PS01326 Diaminopimelate epimerase signature. 85 99 - T 14-10-2018 IPR018510 Diaminopimelate epimerase, active site GO:0005737|GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 MB46_03935 07a158aae934fb9d6fa46a2fce5c97b4 305 Gene3D G3DSA:3.10.310.10 155 284 2.4E-32 T 14-10-2018 MB46_03935 07a158aae934fb9d6fa46a2fce5c97b4 305 SUPERFAMILY SSF54506 169 303 1.82E-27 T 14-10-2018 MB46_03935 07a158aae934fb9d6fa46a2fce5c97b4 305 Pfam PF01678 Diaminopimelate epimerase 174 279 2.3E-15 T 14-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 MB46_03935 07a158aae934fb9d6fa46a2fce5c97b4 305 Pfam PF01678 Diaminopimelate epimerase 13 144 9.4E-29 T 14-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 MB46_03935 07a158aae934fb9d6fa46a2fce5c97b4 305 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 11 304 3.0E-56 T 14-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 MB46_16895 52d86eaf53b307f178cad35f68a07d88 387 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 168 366 5.1E-12 T 14-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain MB46_16895 52d86eaf53b307f178cad35f68a07d88 387 Gene3D G3DSA:3.40.50.720 15 366 7.3E-51 T 14-10-2018 MB46_16895 52d86eaf53b307f178cad35f68a07d88 387 SUPERFAMILY SSF51735 164 319 1.5E-15 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_16895 52d86eaf53b307f178cad35f68a07d88 387 SMART SM01003 11 148 7.0E-21 T 14-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal MB46_16895 52d86eaf53b307f178cad35f68a07d88 387 Gene3D G3DSA:3.40.50.720 141 321 7.3E-51 T 14-10-2018 MB46_16895 52d86eaf53b307f178cad35f68a07d88 387 SMART SM01002 151 313 1.1E-6 T 14-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain MB46_16895 52d86eaf53b307f178cad35f68a07d88 387 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 17 129 1.4E-12 T 14-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal MB46_16895 52d86eaf53b307f178cad35f68a07d88 387 SUPERFAMILY SSF52283 12 184 6.29E-29 T 14-10-2018 MB46_01630 81e2b6f77973af636cf314a80a999025 349 SUPERFAMILY SSF56601 3 345 3.66E-67 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like MB46_01630 81e2b6f77973af636cf314a80a999025 349 Pfam PF00144 Beta-lactamase 8 329 3.9E-52 T 14-10-2018 IPR001466 Beta-lactamase-related MB46_01630 81e2b6f77973af636cf314a80a999025 349 Gene3D G3DSA:3.40.710.10 1 348 4.4E-77 T 14-10-2018 MB46_10940 9eea4e989fc565109e72d52aaf2f336b 367 PIRSF PIRSF038945 1 365 1.6E-152 T 14-10-2018 IPR026260 Threonine synthase, bacterial/archaeal GO:0004795|GO:0009088 KEGG: 00260+4.2.3.1|KEGG: 00750+4.2.3.1 MB46_10940 9eea4e989fc565109e72d52aaf2f336b 367 SUPERFAMILY SSF53686 6 345 9.43E-102 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme MB46_10940 9eea4e989fc565109e72d52aaf2f336b 367 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 53 66 - T 14-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 MB46_10940 9eea4e989fc565109e72d52aaf2f336b 367 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 25 329 5.6E-71 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme MB46_10940 9eea4e989fc565109e72d52aaf2f336b 367 TIGRFAM TIGR00260 thrC: threonine synthase 10 336 7.1E-88 T 14-10-2018 IPR004450 Threonine synthase-like MB46_10940 9eea4e989fc565109e72d52aaf2f336b 367 Gene3D G3DSA:3.40.50.1100 12 335 7.3E-115 T 14-10-2018 MB46_10940 9eea4e989fc565109e72d52aaf2f336b 367 Gene3D G3DSA:3.40.50.1100 61 157 7.3E-115 T 14-10-2018 MB46_17290 d60687b12f0d9c9a1e276ed0fe7ad0e7 410 SMART SM00530 8 62 3.2E-8 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MB46_17290 d60687b12f0d9c9a1e276ed0fe7ad0e7 410 SUPERFAMILY SSF48452 82 218 1.36E-7 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MB46_17290 d60687b12f0d9c9a1e276ed0fe7ad0e7 410 SUPERFAMILY SSF47413 4 60 6.81E-10 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MB46_17290 d60687b12f0d9c9a1e276ed0fe7ad0e7 410 Pfam PF13560 Helix-turn-helix domain 5 65 9.7E-8 T 14-10-2018 MB46_17290 d60687b12f0d9c9a1e276ed0fe7ad0e7 410 Gene3D G3DSA:1.25.40.10 63 409 6.1E-11 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MB46_17290 d60687b12f0d9c9a1e276ed0fe7ad0e7 410 Gene3D G3DSA:1.10.260.40 3 62 1.8E-10 T 14-10-2018 MB46_02165 cdf8b5f1c2bd4b833c875eca0c4f3b90 571 Gene3D G3DSA:3.30.450.20 39 186 1.3E-39 T 14-10-2018 MB46_02165 cdf8b5f1c2bd4b833c875eca0c4f3b90 571 SUPERFAMILY SSF103190 41 181 1.18E-22 T 14-10-2018 IPR029151 Periplasmic sensor-like domain superfamily MB46_02165 cdf8b5f1c2bd4b833c875eca0c4f3b90 571 Pfam PF17203 Single cache domain 3 45 182 2.3E-18 T 14-10-2018 IPR033463 Single cache domain 3 MB46_02165 cdf8b5f1c2bd4b833c875eca0c4f3b90 571 Gene3D G3DSA:3.30.450.20 217 334 1.9E-10 T 14-10-2018 MB46_02165 cdf8b5f1c2bd4b833c875eca0c4f3b90 571 Gene3D G3DSA:3.30.565.10 404 560 2.4E-19 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MB46_02165 cdf8b5f1c2bd4b833c875eca0c4f3b90 571 SMART SM00387 438 561 3.8E-19 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MB46_02165 cdf8b5f1c2bd4b833c875eca0c4f3b90 571 PRINTS PR00344 Bacterial sensor protein C-terminal signature 483 497 1.5E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MB46_02165 cdf8b5f1c2bd4b833c875eca0c4f3b90 571 PRINTS PR00344 Bacterial sensor protein C-terminal signature 545 558 1.5E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MB46_02165 cdf8b5f1c2bd4b833c875eca0c4f3b90 571 PRINTS PR00344 Bacterial sensor protein C-terminal signature 500 510 1.5E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MB46_02165 cdf8b5f1c2bd4b833c875eca0c4f3b90 571 PRINTS PR00344 Bacterial sensor protein C-terminal signature 518 536 1.5E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MB46_02165 cdf8b5f1c2bd4b833c875eca0c4f3b90 571 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 439 558 6.2E-13 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MB46_02165 cdf8b5f1c2bd4b833c875eca0c4f3b90 571 SUPERFAMILY SSF55874 407 558 8.66E-21 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MB46_02165 cdf8b5f1c2bd4b833c875eca0c4f3b90 571 Pfam PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain 343 387 2.8E-10 T 14-10-2018 IPR039506 SpoOB, alpha-helical domain MB46_17140 7e674c8848de0ce29f394ba19cda3998 571 Gene3D G3DSA:3.40.50.300 1 213 4.8E-64 T 14-10-2018 MB46_17140 7e674c8848de0ce29f394ba19cda3998 571 SUPERFAMILY SSF52540 78 356 1.49E-60 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_17140 7e674c8848de0ce29f394ba19cda3998 571 SMART SM00490 260 341 1.2E-25 T 14-10-2018 IPR001650 Helicase, C-terminal MB46_17140 7e674c8848de0ce29f394ba19cda3998 571 Pfam PF00271 Helicase conserved C-terminal domain 241 341 1.9E-22 T 14-10-2018 IPR001650 Helicase, C-terminal MB46_17140 7e674c8848de0ce29f394ba19cda3998 571 SMART SM00487 21 225 1.0E-46 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MB46_17140 7e674c8848de0ce29f394ba19cda3998 571 Gene3D G3DSA:3.40.50.300 219 404 1.7E-40 T 14-10-2018 MB46_17140 7e674c8848de0ce29f394ba19cda3998 571 Pfam PF00270 DEAD/DEAH box helicase 26 198 2.0E-43 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MB46_09250 13a04fcc866c78f35966991d62b52a83 355 SUPERFAMILY SSF48264 2 350 1.22E-37 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 MB46_09250 13a04fcc866c78f35966991d62b52a83 355 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 296 305 - T 14-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 MB46_09250 13a04fcc866c78f35966991d62b52a83 355 PRINTS PR00359 B-class P450 signature 303 314 1.0E-6 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MB46_09250 13a04fcc866c78f35966991d62b52a83 355 PRINTS PR00359 B-class P450 signature 105 121 1.0E-6 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MB46_09250 13a04fcc866c78f35966991d62b52a83 355 PRINTS PR00359 B-class P450 signature 294 303 1.0E-6 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MB46_09250 13a04fcc866c78f35966991d62b52a83 355 Gene3D G3DSA:1.10.630.10 1 354 7.0E-46 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 MB46_14910 f9a9e2fe498a39fc9d499925965ecc42 138 SUPERFAMILY SSF51735 6 138 8.82E-35 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_14910 f9a9e2fe498a39fc9d499925965ecc42 138 SMART SM00881 14 107 3.7E-15 T 14-10-2018 IPR003781 CoA-binding GO:0048037 MB46_14910 f9a9e2fe498a39fc9d499925965ecc42 138 Pfam PF13380 CoA binding domain 19 132 3.6E-32 T 14-10-2018 IPR003781 CoA-binding GO:0048037 MB46_14910 f9a9e2fe498a39fc9d499925965ecc42 138 Gene3D G3DSA:3.40.50.720 2 137 5.8E-33 T 14-10-2018 MB46_17155 90e7171478ac6b54fc3a2d3cad6ef345 199 Gene3D G3DSA:2.60.120.10 10 109 5.5E-38 T 14-10-2018 IPR014710 RmlC-like jelly roll fold MB46_17155 90e7171478ac6b54fc3a2d3cad6ef345 199 SUPERFAMILY SSF51182 2 151 2.49E-42 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily MB46_17155 90e7171478ac6b54fc3a2d3cad6ef345 199 Pfam PF05962 HutD 8 188 5.6E-47 T 14-10-2018 IPR010282 Uncharacterised protein family HutD/Ves MB46_17155 90e7171478ac6b54fc3a2d3cad6ef345 199 Gene3D G3DSA:2.60.120.10 5 142 5.5E-38 T 14-10-2018 IPR014710 RmlC-like jelly roll fold MB46_19230 a1ed517c8b4b854a3467ba1bf1fdae2a 340 Gene3D G3DSA:3.40.1350.10 194 308 2.8E-7 T 14-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 MB46_19230 a1ed517c8b4b854a3467ba1bf1fdae2a 340 Pfam PF06250 Protein of unknown function (DUF1016) 18 319 5.9E-103 T 14-10-2018 IPR009362 Protein of unknown function DUF1016 MB46_15675 d744b0792b103de316af1379dbe9ee2a 339 Pfam PF05544 Proline racemase 12 336 6.8E-79 T 14-10-2018 IPR008794 Proline racemase family MB46_15675 d744b0792b103de316af1379dbe9ee2a 339 Gene3D G3DSA:3.10.310.10 149 315 2.2E-103 T 14-10-2018 MB46_15675 d744b0792b103de316af1379dbe9ee2a 339 Gene3D G3DSA:3.10.310.10 8 338 2.2E-103 T 14-10-2018 MB46_15675 d744b0792b103de316af1379dbe9ee2a 339 PIRSF PIRSF029792 4 339 2.0E-82 T 14-10-2018 IPR008794 Proline racemase family MB46_15675 d744b0792b103de316af1379dbe9ee2a 339 SUPERFAMILY SSF54506 8 336 2.22E-81 T 14-10-2018 MB46_15190 8671a9e0e653c2833aeb4c1b5f57a7b6 480 PIRSF PIRSF006060 2 460 3.3E-71 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 MB46_15190 8671a9e0e653c2833aeb4c1b5f57a7b6 480 Pfam PF00324 Amino acid permease 16 451 4.7E-106 T 14-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 MB46_15190 8671a9e0e653c2833aeb4c1b5f57a7b6 480 Gene3D G3DSA:1.20.1740.10 8 463 1.6E-66 T 14-10-2018 MB46_15190 8671a9e0e653c2833aeb4c1b5f57a7b6 480 ProSitePatterns PS00218 Amino acid permeases signature. 41 71 - T 14-10-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 MB46_01810 6dfb8b5b693c5997445b49d331fa7b69 269 Hamap MF_01830 Putative hydro-lyase . 16 268 51.217 T 14-10-2018 IPR016938 Uncharacterised protein family UPF0317 MB46_01810 6dfb8b5b693c5997445b49d331fa7b69 269 Gene3D G3DSA:3.40.1640.10 25 256 1.5E-89 T 14-10-2018 MB46_01810 6dfb8b5b693c5997445b49d331fa7b69 269 SUPERFAMILY SSF160920 14 261 1.24E-108 T 14-10-2018 IPR038021 Putative hydro-lyase MB46_01810 6dfb8b5b693c5997445b49d331fa7b69 269 PIRSF PIRSF029755 5 269 4.4E-114 T 14-10-2018 IPR016938 Uncharacterised protein family UPF0317 MB46_01810 6dfb8b5b693c5997445b49d331fa7b69 269 Gene3D G3DSA:3.30.2040.10 128 240 1.5E-89 T 14-10-2018 MB46_01810 6dfb8b5b693c5997445b49d331fa7b69 269 Pfam PF07286 Protein of unknown function (DUF1445) 118 260 1.2E-63 T 14-10-2018 IPR009906 D-glutamate cyclase MB46_01980 2c63918d91ad0dd511f93e94eec3ba23 402 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 9 356 2.2E-70 T 14-10-2018 IPR006330 Adenosine/adenine deaminase GO:0019239 Reactome: R-HSA-74217 MB46_01980 2c63918d91ad0dd511f93e94eec3ba23 402 Pfam PF00962 Adenosine/AMP deaminase 9 356 9.8E-73 T 14-10-2018 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Reactome: R-HSA-74217 MB46_01980 2c63918d91ad0dd511f93e94eec3ba23 402 Gene3D G3DSA:3.20.20.140 5 376 1.3E-101 T 14-10-2018 MB46_01980 2c63918d91ad0dd511f93e94eec3ba23 402 SUPERFAMILY SSF51556 7 361 3.89E-71 T 14-10-2018 IPR032466 Metal-dependent hydrolase MB46_02510 6e97433a74a9bd6251230da615bc60b2 365 SUPERFAMILY SSF51445 51 329 1.39E-15 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily MB46_02510 6e97433a74a9bd6251230da615bc60b2 365 Gene3D G3DSA:3.20.20.80 42 362 1.0E-82 T 14-10-2018 MB46_00540 22fe8910dcb0c4eea2cdaade50d7b22d 149 Gene3D G3DSA:3.30.70.120 5 133 7.9E-9 T 14-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal MB46_11580 b97c778052440183f21de7fecd7c46ba 1624 SUPERFAMILY SSF51735 962 1297 3.28E-23 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_11580 b97c778052440183f21de7fecd7c46ba 1624 PIRSF PIRSF036761 5 1624 0.0 T 14-10-2018 IPR007780 NAD-glutamate dehydrogenase, bacteria GO:0004352|GO:0019551 KEGG: 00220+1.4.1.2|KEGG: 00250+1.4.1.2|KEGG: 00430+1.4.1.2|KEGG: 00910+1.4.1.2|MetaCyc: PWY-5022|MetaCyc: PWY-6728|MetaCyc: PWY-7126 MB46_11580 b97c778052440183f21de7fecd7c46ba 1624 Pfam PF05088 Bacterial NAD-glutamate dehydrogenase 71 1619 0.0 T 14-10-2018 IPR028971 NAD-glutamate dehydrogenase GO:0004352|GO:0019551 KEGG: 00220+1.4.1.2|KEGG: 00250+1.4.1.2|KEGG: 00430+1.4.1.2|KEGG: 00910+1.4.1.2|MetaCyc: PWY-5022|MetaCyc: PWY-6728|MetaCyc: PWY-7126 MB46_11580 b97c778052440183f21de7fecd7c46ba 1624 SUPERFAMILY SSF53223 775 957 3.02E-22 T 14-10-2018 MB46_17680 b1ba5e7b7b1b3b4d284504b6ed1d53c9 379 Pfam PF05448 Acetyl xylan esterase (AXE1) 223 267 1.1E-5 T 14-10-2018 IPR008391 Acetyl xylan esterase MB46_17680 b1ba5e7b7b1b3b4d284504b6ed1d53c9 379 SUPERFAMILY SSF53474 41 374 1.01E-15 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_18235 a4a63f618ddba3094e7e1f3b65aed33a 432 Gene3D G3DSA:3.40.190.10 56 384 2.1E-79 T 14-10-2018 MB46_18235 a4a63f618ddba3094e7e1f3b65aed33a 432 SUPERFAMILY SSF53850 18 430 8.16E-74 T 14-10-2018 MB46_18235 a4a63f618ddba3094e7e1f3b65aed33a 432 Gene3D G3DSA:3.40.190.10 154 413 2.1E-79 T 14-10-2018 MB46_18235 a4a63f618ddba3094e7e1f3b65aed33a 432 Pfam PF01547 Bacterial extracellular solute-binding protein 58 341 4.8E-52 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein MB46_12000 d773b2adad5075d1b137d7735e96483d 228 Gene3D G3DSA:3.30.420.10 8 186 7.8E-36 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 MB46_12000 d773b2adad5075d1b137d7735e96483d 228 SUPERFAMILY SSF53098 4 181 4.29E-40 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily MB46_12000 d773b2adad5075d1b137d7735e96483d 228 Pfam PF00929 Exonuclease 11 173 3.9E-13 T 14-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III MB46_12000 d773b2adad5075d1b137d7735e96483d 228 SMART SM00479 8 183 3.4E-21 T 14-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III MB46_00370 92d455b08f8f57db5831ed5101ea533e 578 SUPERFAMILY SSF90123 43 344 1.26E-43 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MB46_00370 92d455b08f8f57db5831ed5101ea533e 578 Pfam PF00005 ABC transporter 404 521 5.0E-8 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_00370 92d455b08f8f57db5831ed5101ea533e 578 SUPERFAMILY SSF52540 404 563 8.95E-27 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_00370 92d455b08f8f57db5831ed5101ea533e 578 ProSitePatterns PS00211 ABC transporters family signature. 493 507 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_00370 92d455b08f8f57db5831ed5101ea533e 578 Pfam PF00664 ABC transporter transmembrane region 48 311 3.7E-20 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 MB46_00370 92d455b08f8f57db5831ed5101ea533e 578 Gene3D G3DSA:1.20.1560.10 37 347 2.0E-40 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MB46_00370 92d455b08f8f57db5831ed5101ea533e 578 Gene3D G3DSA:3.40.50.300 384 571 1.6E-31 T 14-10-2018 MB46_05760 6595c19d114fb09066f23f6452627e21 86 Gene3D G3DSA:2.40.50.580 6 81 1.6E-23 T 14-10-2018 MB46_05760 6595c19d114fb09066f23f6452627e21 86 Pfam PF03749 Sugar fermentation stimulation protein 18 77 2.7E-16 T 14-10-2018 IPR005224 Sugar fermentation stimulation protein MB46_11750 07483346022ab9db68ead91b15af5512 257 Gene3D G3DSA:3.40.430.10 12 255 1.9E-54 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 MB46_11750 07483346022ab9db68ead91b15af5512 257 SUPERFAMILY SSF53597 32 254 3.93E-34 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 MB46_11750 07483346022ab9db68ead91b15af5512 257 Pfam PF01872 RibD C-terminal domain 34 241 1.5E-24 T 14-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 MB46_08200 a1bb615fa51857122063d71618c9a862 227 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 3 37 1.5E-14 T 14-10-2018 IPR019933 DivIVA domain MB46_08200 a1bb615fa51857122063d71618c9a862 227 Pfam PF05103 DivIVA protein 3 54 2.3E-12 T 14-10-2018 IPR007793 DivIVA family MB46_05450 396ddaee4be4eb2e589a804c38760c8c 266 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 1 237 13.302 T 14-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 MB46_05450 396ddaee4be4eb2e589a804c38760c8c 266 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 3 225 2.4E-47 T 14-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 MB46_05450 396ddaee4be4eb2e589a804c38760c8c 266 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 100 126 3.1E-27 T 14-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 MB46_05450 396ddaee4be4eb2e589a804c38760c8c 266 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 2 29 3.1E-27 T 14-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 MB46_05450 396ddaee4be4eb2e589a804c38760c8c 266 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 152 180 3.1E-27 T 14-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 MB46_05450 396ddaee4be4eb2e589a804c38760c8c 266 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 82 100 3.1E-27 T 14-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 MB46_05450 396ddaee4be4eb2e589a804c38760c8c 266 Pfam PF00902 Sec-independent protein translocase protein (TatC) 6 220 4.0E-50 T 14-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 MB46_02585 dcad0e0b3dad537003df3cee784c538c 436 SUPERFAMILY SSF53756 18 416 3.87E-38 T 14-10-2018 MB46_02585 dcad0e0b3dad537003df3cee784c538c 436 Gene3D G3DSA:3.40.50.2000 229 400 3.2E-18 T 14-10-2018 MB46_02585 dcad0e0b3dad537003df3cee784c538c 436 Pfam PF00534 Glycosyl transferases group 1 229 396 3.3E-9 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 MB46_02585 dcad0e0b3dad537003df3cee784c538c 436 Pfam PF13579 Glycosyl transferase 4-like domain 32 215 7.7E-19 T 14-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 MB46_02585 dcad0e0b3dad537003df3cee784c538c 436 Gene3D G3DSA:3.40.50.2000 7 228 3.8E-13 T 14-10-2018 MB46_00345 4177ec2aafaccefc3389600603c94217 262 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 70 255 5.9E-26 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_00345 4177ec2aafaccefc3389600603c94217 262 SUPERFAMILY SSF161098 1 262 5.23E-73 T 14-10-2018 IPR035906 MetI-like superfamily MB46_00345 4177ec2aafaccefc3389600603c94217 262 Gene3D G3DSA:1.10.3720.10 1 250 6.9E-67 T 14-10-2018 IPR035906 MetI-like superfamily MB46_19300 70ddae566189274b63f57ed4d2b3e2bc 224 SUPERFAMILY SSF143081 4 221 6.02E-51 T 14-10-2018 IPR036590 SOS response associated peptidase-like MB46_19300 70ddae566189274b63f57ed4d2b3e2bc 224 Gene3D G3DSA:3.90.1680.10 3 222 7.3E-53 T 14-10-2018 IPR036590 SOS response associated peptidase-like MB46_19300 70ddae566189274b63f57ed4d2b3e2bc 224 Pfam PF02586 SOS response associated peptidase (SRAP) 13 209 3.0E-50 T 14-10-2018 IPR003738 SOS response associated peptidase (SRAP) MB46_07475 09301164c0c7d2d86c153645c670c6cf 182 Gene3D G3DSA:3.40.630.30 2 180 1.9E-37 T 14-10-2018 MB46_07475 09301164c0c7d2d86c153645c670c6cf 182 Pfam PF13302 Acetyltransferase (GNAT) domain 8 149 1.4E-23 T 14-10-2018 IPR000182 GNAT domain MB46_07475 09301164c0c7d2d86c153645c670c6cf 182 SUPERFAMILY SSF55729 4 173 6.51E-34 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase MB46_05555 12671ec5fe62ec3729e81070115c8c88 124 Gene3D G3DSA:3.10.180.10 4 122 6.1E-20 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MB46_05555 12671ec5fe62ec3729e81070115c8c88 124 SUPERFAMILY SSF54593 1 123 4.42E-10 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MB46_18660 8e04f4ffcf68fba3b19600519dfd6c35 908 SUPERFAMILY SSF53335 267 686 1.97E-45 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MB46_18660 8e04f4ffcf68fba3b19600519dfd6c35 908 Gene3D G3DSA:3.40.50.150 338 611 3.2E-32 T 14-10-2018 MB46_18660 8e04f4ffcf68fba3b19600519dfd6c35 908 Pfam PF01420 Type I restriction modification DNA specificity domain 712 846 3.2E-9 T 14-10-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 MB46_18660 8e04f4ffcf68fba3b19600519dfd6c35 908 Pfam PF02384 N-6 DNA Methylase 365 493 1.7E-9 T 14-10-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 MB46_09715 46d0f19cce0d7a9455a63ef9283308d1 318 Gene3D G3DSA:1.10.3720.10 56 294 3.4E-50 T 14-10-2018 IPR035906 MetI-like superfamily MB46_09715 46d0f19cce0d7a9455a63ef9283308d1 318 SUPERFAMILY SSF161098 70 280 7.59E-40 T 14-10-2018 IPR035906 MetI-like superfamily MB46_09715 46d0f19cce0d7a9455a63ef9283308d1 318 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 69 183 1.7E-15 T 14-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 MB46_09715 46d0f19cce0d7a9455a63ef9283308d1 318 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 88 287 1.1E-19 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_10945 97777ea678c7d15f1775fdfe0457f678 432 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 181 203 - T 14-10-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 MB46_10945 97777ea678c7d15f1775fdfe0457f678 432 PIRSF PIRSF000098 1 432 7.4E-155 T 14-10-2018 IPR016204 Homoserine dehydrogenase GO:0004412|GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 MB46_10945 97777ea678c7d15f1775fdfe0457f678 432 SUPERFAMILY SSF55347 135 300 2.94E-54 T 14-10-2018 MB46_10945 97777ea678c7d15f1775fdfe0457f678 432 Gene3D G3DSA:3.30.70.260 341 420 5.4E-143 T 14-10-2018 MB46_10945 97777ea678c7d15f1775fdfe0457f678 432 SUPERFAMILY SSF55021 344 424 3.27E-11 T 14-10-2018 MB46_10945 97777ea678c7d15f1775fdfe0457f678 432 Gene3D G3DSA:3.30.360.10 134 340 5.4E-143 T 14-10-2018 MB46_10945 97777ea678c7d15f1775fdfe0457f678 432 Gene3D G3DSA:3.40.50.720 4 332 5.4E-143 T 14-10-2018 MB46_10945 97777ea678c7d15f1775fdfe0457f678 432 SUPERFAMILY SSF51735 2 156 3.95E-29 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_10945 97777ea678c7d15f1775fdfe0457f678 432 Pfam PF01842 ACT domain 348 417 1.4E-12 T 14-10-2018 IPR002912 ACT domain MB46_10945 97777ea678c7d15f1775fdfe0457f678 432 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 10 127 1.6E-18 T 14-10-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 MB46_10945 97777ea678c7d15f1775fdfe0457f678 432 Pfam PF00742 Homoserine dehydrogenase 135 313 6.3E-68 T 14-10-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 MB46_09890 95c7ffeb215a4e0fcce698108911137b 381 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 23 366 1.6E-114 T 14-10-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 MB46_09890 95c7ffeb215a4e0fcce698108911137b 381 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 4 366 1.2E-140 T 14-10-2018 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 MB46_09890 95c7ffeb215a4e0fcce698108911137b 381 SUPERFAMILY SSF53756 4 371 3.84E-124 T 14-10-2018 MB46_09890 95c7ffeb215a4e0fcce698108911137b 381 Gene3D G3DSA:3.40.50.2000 4 362 1.7E-135 T 14-10-2018 MB46_09890 95c7ffeb215a4e0fcce698108911137b 381 Gene3D G3DSA:3.40.50.2000 190 352 1.7E-135 T 14-10-2018 MB46_07205 0f5065c9cf36e1a06af4a60681f1aae7 70 SUPERFAMILY SSF160113 3 55 6.8E-7 T 14-10-2018 IPR036913 YegP-like superfamily MB46_09345 8c3e5f2b2b5ca4c2b83fd9a930b4ee26 481 PRINTS PR00171 Sugar transporter signature 112 131 7.1E-25 T 14-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 MB46_09345 8c3e5f2b2b5ca4c2b83fd9a930b4ee26 481 PRINTS PR00171 Sugar transporter signature 29 39 7.1E-25 T 14-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 MB46_09345 8c3e5f2b2b5ca4c2b83fd9a930b4ee26 481 PRINTS PR00171 Sugar transporter signature 279 289 7.1E-25 T 14-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 MB46_09345 8c3e5f2b2b5ca4c2b83fd9a930b4ee26 481 PRINTS PR00171 Sugar transporter signature 375 396 7.1E-25 T 14-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 MB46_09345 8c3e5f2b2b5ca4c2b83fd9a930b4ee26 481 PRINTS PR00171 Sugar transporter signature 398 410 7.1E-25 T 14-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 MB46_09345 8c3e5f2b2b5ca4c2b83fd9a930b4ee26 481 Gene3D G3DSA:1.20.1250.20 15 475 2.4E-120 T 14-10-2018 MB46_09345 8c3e5f2b2b5ca4c2b83fd9a930b4ee26 481 ProSitePatterns PS00216 Sugar transport proteins signature 1. 323 340 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MB46_09345 8c3e5f2b2b5ca4c2b83fd9a930b4ee26 481 Pfam PF00083 Sugar (and other) transporter 22 473 1.4E-110 T 14-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 MB46_09345 8c3e5f2b2b5ca4c2b83fd9a930b4ee26 481 SUPERFAMILY SSF103473 23 470 7.85E-67 T 14-10-2018 IPR036259 MFS transporter superfamily MB46_09345 8c3e5f2b2b5ca4c2b83fd9a930b4ee26 481 ProSitePatterns PS00217 Sugar transport proteins signature 2. 117 142 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MB46_09345 8c3e5f2b2b5ca4c2b83fd9a930b4ee26 481 TIGRFAM TIGR00879 SP: MFS transporter, sugar porter (SP) family 17 468 7.8E-106 T 14-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 MB46_07250 f7d46756cf8fd77870f70ac9d55e1373 328 Pfam PF01028 Eukaryotic DNA topoisomerase I, catalytic core 84 282 8.2E-22 T 14-10-2018 IPR013500 DNA topoisomerase I, catalytic core, eukaryotic-type GO:0003677|GO:0003917|GO:0006265 MB46_07250 f7d46756cf8fd77870f70ac9d55e1373 328 Gene3D G3DSA:1.10.132.120 92 315 1.9E-56 T 14-10-2018 MB46_07250 f7d46756cf8fd77870f70ac9d55e1373 328 SUPERFAMILY SSF55869 24 85 3.92E-18 T 14-10-2018 IPR035447 DNA topoisomerase I, N-terminal MB46_07250 f7d46756cf8fd77870f70ac9d55e1373 328 PRINTS PR00416 Eukaryotic DNA topoisomerase I signature 124 143 3.6E-9 T 14-10-2018 IPR001631 DNA topoisomerase I GO:0003677|GO:0003917|GO:0006265 MB46_07250 f7d46756cf8fd77870f70ac9d55e1373 328 PRINTS PR00416 Eukaryotic DNA topoisomerase I signature 147 161 3.6E-9 T 14-10-2018 IPR001631 DNA topoisomerase I GO:0003677|GO:0003917|GO:0006265 MB46_07250 f7d46756cf8fd77870f70ac9d55e1373 328 PRINTS PR00416 Eukaryotic DNA topoisomerase I signature 237 251 3.6E-9 T 14-10-2018 IPR001631 DNA topoisomerase I GO:0003677|GO:0003917|GO:0006265 MB46_07250 f7d46756cf8fd77870f70ac9d55e1373 328 PRINTS PR00416 Eukaryotic DNA topoisomerase I signature 286 297 3.6E-9 T 14-10-2018 IPR001631 DNA topoisomerase I GO:0003677|GO:0003917|GO:0006265 MB46_07250 f7d46756cf8fd77870f70ac9d55e1373 328 Gene3D G3DSA:3.90.15.10 115 238 1.9E-56 T 14-10-2018 IPR014711 DNA topoisomerase I, catalytic core, alpha-helical subdomain, eukaryotic-type GO:0003677|GO:0003917|GO:0006265 MB46_07250 f7d46756cf8fd77870f70ac9d55e1373 328 Gene3D G3DSA:3.30.66.10 9 90 5.1E-30 T 14-10-2018 IPR035447 DNA topoisomerase I, N-terminal MB46_07250 f7d46756cf8fd77870f70ac9d55e1373 328 SUPERFAMILY SSF56349 80 306 4.12E-45 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MB46_11420 a76d69504938901ad868d16a31ce30ea 308 SUPERFAMILY SSF53448 10 213 2.76E-28 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MB46_11420 a76d69504938901ad868d16a31ce30ea 308 Pfam PF00535 Glycosyl transferase family 2 12 125 4.2E-15 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MB46_11420 a76d69504938901ad868d16a31ce30ea 308 Gene3D G3DSA:3.90.550.10 6 211 8.8E-22 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MB46_00430 5ca54f84fbb55d11bd151c87971ba7cd 293 Gene3D G3DSA:1.10.3720.10 47 292 5.8E-64 T 14-10-2018 IPR035906 MetI-like superfamily MB46_00430 5ca54f84fbb55d11bd151c87971ba7cd 293 SUPERFAMILY SSF161098 51 279 3.92E-54 T 14-10-2018 IPR035906 MetI-like superfamily MB46_00430 5ca54f84fbb55d11bd151c87971ba7cd 293 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 97 289 2.3E-18 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_16805 699527d02d4084fb16217db01093fbf8 309 SUPERFAMILY SSF81342 66 272 3.06E-19 T 14-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 MB46_16805 699527d02d4084fb16217db01093fbf8 309 Pfam PF01292 Prokaryotic cytochrome b561 68 264 5.8E-13 T 14-10-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 MB46_16805 699527d02d4084fb16217db01093fbf8 309 Gene3D G3DSA:1.20.950.20 66 258 1.3E-5 T 14-10-2018 MB46_18780 735d852ecc498b40e2562b28c1b67910 678 SUPERFAMILY SSF161098 76 263 3.4E-22 T 14-10-2018 IPR035906 MetI-like superfamily MB46_18780 735d852ecc498b40e2562b28c1b67910 678 SMART SM00382 377 572 2.3E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_18780 735d852ecc498b40e2562b28c1b67910 678 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 574 630 1.1E-6 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MB46_18780 735d852ecc498b40e2562b28c1b67910 678 ProSitePatterns PS00211 ABC transporters family signature. 495 509 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_18780 735d852ecc498b40e2562b28c1b67910 678 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 20 52 2.0E-6 T 14-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain MB46_18780 735d852ecc498b40e2562b28c1b67910 678 Gene3D G3DSA:1.10.3720.10 71 277 2.3E-17 T 14-10-2018 IPR035906 MetI-like superfamily MB46_18780 735d852ecc498b40e2562b28c1b67910 678 Gene3D G3DSA:3.40.50.300 346 675 1.1E-82 T 14-10-2018 MB46_18780 735d852ecc498b40e2562b28c1b67910 678 SUPERFAMILY SSF52540 348 593 1.07E-56 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_18780 735d852ecc498b40e2562b28c1b67910 678 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 99 272 2.2E-22 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_18780 735d852ecc498b40e2562b28c1b67910 678 Pfam PF00005 ABC transporter 369 522 2.4E-25 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_16160 a7707343fd50147dcdbcc6aa3d5470f0 180 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 10 176 4.0E-41 T 14-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 MB46_16160 a7707343fd50147dcdbcc6aa3d5470f0 180 SUPERFAMILY SSF50891 8 177 4.09E-56 T 14-10-2018 IPR029000 Cyclophilin-like domain superfamily MB46_16160 a7707343fd50147dcdbcc6aa3d5470f0 180 PIRSF PIRSF001467 2 179 4.9E-52 T 14-10-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 MB46_16160 a7707343fd50147dcdbcc6aa3d5470f0 180 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 58 75 - T 14-10-2018 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 MB46_16160 a7707343fd50147dcdbcc6aa3d5470f0 180 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 107 122 1.4E-22 T 14-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 MB46_16160 a7707343fd50147dcdbcc6aa3d5470f0 180 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 135 150 1.4E-22 T 14-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 MB46_16160 a7707343fd50147dcdbcc6aa3d5470f0 180 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 63 75 1.4E-22 T 14-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 MB46_16160 a7707343fd50147dcdbcc6aa3d5470f0 180 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 122 134 1.4E-22 T 14-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 MB46_16160 a7707343fd50147dcdbcc6aa3d5470f0 180 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 22 37 1.4E-22 T 14-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 MB46_16160 a7707343fd50147dcdbcc6aa3d5470f0 180 Gene3D G3DSA:2.40.100.10 4 178 6.4E-64 T 14-10-2018 IPR029000 Cyclophilin-like domain superfamily MB46_01935 73693ffe8f26640f81e35bf3a6806780 381 SUPERFAMILY SSF159283 319 373 6.28E-12 T 14-10-2018 MB46_01935 73693ffe8f26640f81e35bf3a6806780 381 Pfam PF00483 Nucleotidyl transferase 22 306 4.2E-42 T 14-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 MB46_01935 73693ffe8f26640f81e35bf3a6806780 381 Gene3D G3DSA:3.90.550.10 20 375 1.9E-103 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MB46_01935 73693ffe8f26640f81e35bf3a6806780 381 SUPERFAMILY SSF53448 20 302 5.32E-52 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MB46_14815 0fb87359ef5eb3b5ba8dd383dabf727e 423 SUPERFAMILY SSF51621 90 337 2.3E-13 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 MB46_14815 0fb87359ef5eb3b5ba8dd383dabf727e 423 Gene3D G3DSA:3.20.20.60 92 321 1.7E-12 T 14-10-2018 MB46_17690 932daab732249c6f2e5dd6cb9c64eba6 428 Pfam PF13416 Bacterial extracellular solute-binding protein 54 353 1.3E-31 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein MB46_17690 932daab732249c6f2e5dd6cb9c64eba6 428 Gene3D G3DSA:3.40.190.10 145 421 7.5E-116 T 14-10-2018 MB46_17690 932daab732249c6f2e5dd6cb9c64eba6 428 SUPERFAMILY SSF53850 34 424 2.69E-53 T 14-10-2018 MB46_17690 932daab732249c6f2e5dd6cb9c64eba6 428 Gene3D G3DSA:3.40.190.10 38 373 7.5E-116 T 14-10-2018 MB46_10760 583c416f3e079fe684bc1ff8d1a506ff 589 SUPERFAMILY SSF52540 24 184 1.21E-22 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_10760 583c416f3e079fe684bc1ff8d1a506ff 589 Gene3D G3DSA:3.40.50.300 18 194 1.1E-19 T 14-10-2018 MB46_10760 583c416f3e079fe684bc1ff8d1a506ff 589 Pfam PF04851 Type III restriction enzyme, res subunit 26 179 6.0E-15 T 14-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 MB46_10760 583c416f3e079fe684bc1ff8d1a506ff 589 Gene3D G3DSA:3.40.50.300 207 414 7.9E-15 T 14-10-2018 MB46_10760 583c416f3e079fe684bc1ff8d1a506ff 589 SUPERFAMILY SSF52540 141 392 1.1E-16 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_10760 583c416f3e079fe684bc1ff8d1a506ff 589 SMART SM00487 23 201 5.3E-9 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MB46_04440 e6f2ef399dde0c93815f8e3bd7c19a89 293 Pfam PF13614 AAA domain 39 215 2.4E-63 T 14-10-2018 IPR025669 AAA domain MB46_04440 e6f2ef399dde0c93815f8e3bd7c19a89 293 SUPERFAMILY SSF52540 38 288 5.47E-66 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_04440 e6f2ef399dde0c93815f8e3bd7c19a89 293 Gene3D G3DSA:3.40.50.300 33 290 1.5E-82 T 14-10-2018 MB46_09285 0d687d70879ae0f0fb00e71ad596f320 307 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 46 258 4.6E-39 T 14-10-2018 IPR018713 Domain of unknown function DUF2236 MB46_13575 38809837a4ff8a0d5c0c1683ef37ecc6 501 Gene3D G3DSA:1.20.1250.20 261 486 2.0E-20 T 14-10-2018 MB46_13575 38809837a4ff8a0d5c0c1683ef37ecc6 501 Pfam PF07690 Major Facilitator Superfamily 14 410 3.2E-57 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MB46_13575 38809837a4ff8a0d5c0c1683ef37ecc6 501 SUPERFAMILY SSF103473 7 476 1.7E-69 T 14-10-2018 IPR036259 MFS transporter superfamily MB46_13575 38809837a4ff8a0d5c0c1683ef37ecc6 501 Gene3D G3DSA:1.20.1720.10 11 219 6.3E-54 T 14-10-2018 MB46_13575 38809837a4ff8a0d5c0c1683ef37ecc6 501 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 11 425 7.5E-94 T 14-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 MB46_19895 67d2bfbf3f30eaa7396f105410028e3d 200 Gene3D G3DSA:2.40.260.10 18 181 8.9E-15 T 14-10-2018 IPR023365 Sortase domain superfamily MB46_19895 67d2bfbf3f30eaa7396f105410028e3d 200 SUPERFAMILY SSF63817 56 177 5.3E-10 T 14-10-2018 IPR023365 Sortase domain superfamily MB46_19895 67d2bfbf3f30eaa7396f105410028e3d 200 Pfam PF04203 Sortase family 58 176 4.5E-9 T 14-10-2018 IPR005754 Sortase family MB46_04475 3c0084d23780d650951a17c4071a474c 518 Gene3D G3DSA:3.40.50.300 255 426 1.5E-40 T 14-10-2018 MB46_04475 3c0084d23780d650951a17c4071a474c 518 Pfam PF01926 50S ribosome-binding GTPase 83 197 4.0E-26 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 MB46_04475 3c0084d23780d650951a17c4071a474c 518 Pfam PF01926 50S ribosome-binding GTPase 257 375 7.0E-21 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 MB46_04475 3c0084d23780d650951a17c4071a474c 518 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 81 509 5.5E-155 T 14-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 MB46_04475 3c0084d23780d650951a17c4071a474c 518 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 256 414 3.6E-22 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MB46_04475 3c0084d23780d650951a17c4071a474c 518 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 80 200 1.2E-25 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MB46_04475 3c0084d23780d650951a17c4071a474c 518 SMART SM00382 79 243 0.0011 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_04475 3c0084d23780d650951a17c4071a474c 518 SMART SM00382 254 397 0.2 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_04475 3c0084d23780d650951a17c4071a474c 518 Hamap MF_00195 GTPase Der [der]. 80 512 35.184 T 14-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 MB46_04475 3c0084d23780d650951a17c4071a474c 518 SUPERFAMILY SSF52540 82 244 1.41E-43 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_04475 3c0084d23780d650951a17c4071a474c 518 Gene3D G3DSA:3.30.300.20 431 512 3.2E-24 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta MB46_04475 3c0084d23780d650951a17c4071a474c 518 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 431 509 2.4E-23 T 14-10-2018 IPR032859 GTPase Der, C-terminal KH-domain-like MB46_04475 3c0084d23780d650951a17c4071a474c 518 Gene3D G3DSA:3.40.50.300 79 239 2.0E-45 T 14-10-2018 MB46_04475 3c0084d23780d650951a17c4071a474c 518 PIRSF PIRSF006485 79 517 4.2E-156 T 14-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 MB46_04475 3c0084d23780d650951a17c4071a474c 518 SUPERFAMILY SSF52540 215 512 1.16E-60 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_04475 3c0084d23780d650951a17c4071a474c 518 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 258 278 3.2E-6 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 MB46_04475 3c0084d23780d650951a17c4071a474c 518 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 307 322 3.2E-6 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 MB46_02225 9afb21b9d757399bd16c6ca4c36a9207 537 Gene3D G3DSA:1.10.260.150 174 454 4.9E-54 T 14-10-2018 MB46_02225 9afb21b9d757399bd16c6ca4c36a9207 537 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 200 381 3.5E-22 T 14-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain MB46_02225 9afb21b9d757399bd16c6ca4c36a9207 537 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 200 381 1.5E-20 T 14-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain MB46_12280 ec86cb4263f2061e44cc7124a9a441e6 327 Pfam PF03466 LysR substrate binding domain 99 305 3.7E-45 T 14-10-2018 IPR005119 LysR, substrate-binding MB46_12280 ec86cb4263f2061e44cc7124a9a441e6 327 Gene3D G3DSA:3.40.190.290 100 311 1.2E-47 T 14-10-2018 MB46_12280 ec86cb4263f2061e44cc7124a9a441e6 327 SUPERFAMILY SSF46785 14 90 7.05E-14 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_12280 ec86cb4263f2061e44cc7124a9a441e6 327 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 17 70 1.5E-12 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MB46_12280 ec86cb4263f2061e44cc7124a9a441e6 327 Gene3D G3DSA:1.10.10.10 6 93 5.8E-15 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_12280 ec86cb4263f2061e44cc7124a9a441e6 327 SUPERFAMILY SSF53850 100 309 5.01E-43 T 14-10-2018 MB46_16725 a7265149a5798c0706a4f9a965a73f12 351 Pfam PF01497 Periplasmic binding protein 67 314 5.3E-26 T 14-10-2018 IPR002491 ABC transporter periplasmic binding domain MB46_16725 a7265149a5798c0706a4f9a965a73f12 351 SUPERFAMILY SSF53807 49 344 7.46E-44 T 14-10-2018 MB46_16725 a7265149a5798c0706a4f9a965a73f12 351 Gene3D G3DSA:3.40.50.1980 43 188 3.7E-37 T 14-10-2018 MB46_16725 a7265149a5798c0706a4f9a965a73f12 351 Gene3D G3DSA:3.40.50.1980 190 351 3.0E-51 T 14-10-2018 MB46_16835 72894d3d85bf63345e4fe03c6a14d5b5 55 SUPERFAMILY SSF57829 3 55 3.24E-18 T 14-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 MB46_16835 72894d3d85bf63345e4fe03c6a14d5b5 55 ProSitePatterns PS00582 Ribosomal protein L33 signature. 23 42 - T 14-10-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MB46_16835 72894d3d85bf63345e4fe03c6a14d5b5 55 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 4 55 1.1E-21 T 14-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_16835 72894d3d85bf63345e4fe03c6a14d5b5 55 Pfam PF00471 Ribosomal protein L33 10 55 1.6E-17 T 14-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_16835 72894d3d85bf63345e4fe03c6a14d5b5 55 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 2 55 14.569 T 14-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_16835 72894d3d85bf63345e4fe03c6a14d5b5 55 Gene3D G3DSA:2.20.28.120 2 55 1.7E-25 T 14-10-2018 IPR038584 Ribosomal protein L33 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_08270 7a3ada0e9b3a66a60af32642b6ad79d5 582 Gene3D G3DSA:3.40.710.10 290 482 2.9E-88 T 14-10-2018 MB46_08270 7a3ada0e9b3a66a60af32642b6ad79d5 582 Pfam PF03717 Penicillin-binding Protein dimerisation domain 44 211 2.8E-13 T 14-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 MB46_08270 7a3ada0e9b3a66a60af32642b6ad79d5 582 Gene3D G3DSA:3.90.1310.30 37 228 3.4E-35 T 14-10-2018 MB46_08270 7a3ada0e9b3a66a60af32642b6ad79d5 582 Pfam PF00905 Penicillin binding protein transpeptidase domain 255 546 7.2E-60 T 14-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 MB46_08270 7a3ada0e9b3a66a60af32642b6ad79d5 582 SUPERFAMILY SSF56519 41 228 1.23E-32 T 14-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 MB46_08270 7a3ada0e9b3a66a60af32642b6ad79d5 582 SUPERFAMILY SSF56601 182 576 1.8E-78 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like MB46_08270 7a3ada0e9b3a66a60af32642b6ad79d5 582 Gene3D G3DSA:3.30.450.330 230 563 2.9E-88 T 14-10-2018 MB46_13395 9570370665312ffad0a292f2a1d0dee5 107 TIGRFAM TIGR00012 L29: ribosomal protein uL29 19 67 1.2E-17 T 14-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MB46_13395 9570370665312ffad0a292f2a1d0dee5 107 SUPERFAMILY SSF46561 11 70 1.96E-19 T 14-10-2018 IPR036049 Ribosomal protein L29/L35 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MB46_13395 9570370665312ffad0a292f2a1d0dee5 107 Pfam PF00831 Ribosomal L29 protein 13 67 1.0E-21 T 14-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MB46_13395 9570370665312ffad0a292f2a1d0dee5 107 Gene3D G3DSA:1.10.287.310 9 72 6.3E-22 T 14-10-2018 MB46_13395 9570370665312ffad0a292f2a1d0dee5 107 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 8 67 15.199 T 14-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MB46_12675 77837d59ccb9153803994c7d51161287 286 Gene3D G3DSA:3.40.50.1820 18 255 2.1E-20 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_12675 77837d59ccb9153803994c7d51161287 286 Pfam PF02230 Phospholipase/Carboxylesterase 109 173 1.7E-7 T 14-10-2018 IPR003140 Phospholipase/carboxylesterase/thioesterase GO:0016787 MB46_12675 77837d59ccb9153803994c7d51161287 286 SUPERFAMILY SSF53474 33 252 2.81E-20 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_01170 10ee621378d23233046278967a5e8740 610 Gene3D G3DSA:3.30.565.10 2 204 1.0E-45 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MB46_01170 10ee621378d23233046278967a5e8740 610 SUPERFAMILY SSF110942 537 588 2.75E-5 T 14-10-2018 IPR037196 HSP90, C-terminal domain MB46_01170 10ee621378d23233046278967a5e8740 610 SUPERFAMILY SSF55874 7 200 3.87E-39 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MB46_01170 10ee621378d23233046278967a5e8740 610 PIRSF PIRSF002583 2 207 3.4E-48 T 14-10-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 MB46_01170 10ee621378d23233046278967a5e8740 610 PIRSF PIRSF002583 243 610 2.2E-33 T 14-10-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 MB46_01170 10ee621378d23233046278967a5e8740 610 Gene3D G3DSA:3.30.230.80 264 373 1.9E-9 T 14-10-2018 MB46_01170 10ee621378d23233046278967a5e8740 610 PRINTS PR00775 90kDa heat shock protein signature 162 179 1.0E-16 T 14-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal MB46_01170 10ee621378d23233046278967a5e8740 610 PRINTS PR00775 90kDa heat shock protein signature 29 51 1.0E-16 T 14-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal MB46_01170 10ee621378d23233046278967a5e8740 610 PRINTS PR00775 90kDa heat shock protein signature 180 198 1.0E-16 T 14-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal MB46_01170 10ee621378d23233046278967a5e8740 610 PRINTS PR00775 90kDa heat shock protein signature 111 133 1.0E-16 T 14-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal MB46_01170 10ee621378d23233046278967a5e8740 610 PRINTS PR00775 90kDa heat shock protein signature 8 28 1.0E-16 T 14-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal MB46_01170 10ee621378d23233046278967a5e8740 610 SUPERFAMILY SSF54211 242 443 1.82E-25 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MB46_18750 6530412937cbc03b84d84828660a35ff 678 TIGRFAM TIGR03062 pip_yhgE_Cterm: YhgE/Pip C-terminal domain 461 665 1.5E-65 T 14-10-2018 IPR017501 Phage infection protein, YhgE, C-terminal MB46_18750 6530412937cbc03b84d84828660a35ff 678 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 187 212 3.5E-5 T 14-10-2018 IPR023908 xxxLxxG heptad repeat MB46_18750 6530412937cbc03b84d84828660a35ff 678 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 403 425 1.5E-4 T 14-10-2018 IPR023908 xxxLxxG heptad repeat MB46_18750 6530412937cbc03b84d84828660a35ff 678 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 412 437 2.5E-4 T 14-10-2018 IPR023908 xxxLxxG heptad repeat MB46_18750 6530412937cbc03b84d84828660a35ff 678 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 373 397 8.7E-5 T 14-10-2018 IPR023908 xxxLxxG heptad repeat MB46_18750 6530412937cbc03b84d84828660a35ff 678 TIGRFAM TIGR03061 pip_yhgE_Nterm: YhgE/Pip N-terminal domain 9 174 1.4E-50 T 14-10-2018 IPR017500 Phage infection protein, YhgE, N-terminal MB46_18750 6530412937cbc03b84d84828660a35ff 678 Pfam PF12698 ABC-2 family transporter protein 450 658 5.3E-18 T 14-10-2018 MB46_18750 6530412937cbc03b84d84828660a35ff 678 Pfam PF12051 Protein of unknown function (DUF3533) 24 183 1.5E-8 T 14-10-2018 IPR022703 Domain of unknown function DUF3533 MB46_01200 f49ee0447d674f6a06b983639eba2b5c 158 Pfam PF00583 Acetyltransferase (GNAT) family 33 127 1.1E-11 T 14-10-2018 IPR000182 GNAT domain MB46_01200 f49ee0447d674f6a06b983639eba2b5c 158 SUPERFAMILY SSF55729 4 157 1.17E-23 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase MB46_01200 f49ee0447d674f6a06b983639eba2b5c 158 Gene3D G3DSA:3.40.630.30 1 158 6.2E-36 T 14-10-2018 MB46_11890 b63fe7a28a5dad1ac20f5b940a0adf72 178 SUPERFAMILY SSF46785 31 163 2.93E-25 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_11890 b63fe7a28a5dad1ac20f5b940a0adf72 178 SMART SM00347 50 151 8.6E-19 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MB46_11890 b63fe7a28a5dad1ac20f5b940a0adf72 178 Pfam PF01047 MarR family 76 116 1.2E-8 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MB46_11890 b63fe7a28a5dad1ac20f5b940a0adf72 178 Gene3D G3DSA:1.10.10.10 26 170 3.3E-31 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_17670 1b61c8d21d9e496de128e09168253360 435 Gene3D G3DSA:3.40.190.10 41 377 5.7E-117 T 14-10-2018 MB46_17670 1b61c8d21d9e496de128e09168253360 435 Gene3D G3DSA:3.40.190.10 147 426 5.7E-117 T 14-10-2018 MB46_17670 1b61c8d21d9e496de128e09168253360 435 Pfam PF01547 Bacterial extracellular solute-binding protein 56 338 2.2E-30 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein MB46_17670 1b61c8d21d9e496de128e09168253360 435 SUPERFAMILY SSF53850 25 430 8.69E-58 T 14-10-2018 MB46_01090 2bf47bd66d50112065a95f1923cc1b66 456 Gene3D G3DSA:3.50.50.60 2 104 6.6E-9 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_01090 2bf47bd66d50112065a95f1923cc1b66 456 Pfam PF13450 NAD(P)-binding Rossmann-like domain 11 47 1.1E-5 T 14-10-2018 MB46_01090 2bf47bd66d50112065a95f1923cc1b66 456 SUPERFAMILY SSF51905 8 226 4.44E-13 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_02625 cc3a842741c9ad2c48c0d063736d6eb6 441 TIGRFAM TIGR00773 NhaA: Na+/H+ antiporter NhaA 34 411 1.0E-92 T 14-10-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 MB46_02625 cc3a842741c9ad2c48c0d063736d6eb6 441 Pfam PF06965 Na+/H+ antiporter 1 32 412 3.3E-128 T 14-10-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 MB46_02625 cc3a842741c9ad2c48c0d063736d6eb6 441 Hamap MF_01844 Na(+)/H(+) antiporter NhaA [nhaA]. 30 418 20.403 T 14-10-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 MB46_02625 cc3a842741c9ad2c48c0d063736d6eb6 441 Gene3D G3DSA:1.20.1530.10 27 420 5.6E-135 T 14-10-2018 IPR023171 Na/H antiporter domain superfamily MB46_02790 fc12ff8b921f6afc1094e9db2945ac89 602 Pfam PF00289 Biotin carboxylase, N-terminal domain 15 123 5.5E-43 T 14-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MB46_02790 fc12ff8b921f6afc1094e9db2945ac89 602 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 299 306 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MB46_02790 fc12ff8b921f6afc1094e9db2945ac89 602 SUPERFAMILY SSF51246 342 461 1.1E-35 T 14-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 MB46_02790 fc12ff8b921f6afc1094e9db2945ac89 602 Gene3D G3DSA:2.40.50.100 529 602 8.5E-22 T 14-10-2018 MB46_02790 fc12ff8b921f6afc1094e9db2945ac89 602 Gene3D G3DSA:3.30.470.130 4 463 2.9E-173 T 14-10-2018 MB46_02790 fc12ff8b921f6afc1094e9db2945ac89 602 SUPERFAMILY SSF52440 11 126 1.08E-45 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily MB46_02790 fc12ff8b921f6afc1094e9db2945ac89 602 SUPERFAMILY SSF51230 528 601 3.99E-21 T 14-10-2018 IPR011053 Single hybrid motif MB46_02790 fc12ff8b921f6afc1094e9db2945ac89 602 SUPERFAMILY SSF56059 96 341 1.18E-58 T 14-10-2018 MB46_02790 fc12ff8b921f6afc1094e9db2945ac89 602 Pfam PF00364 Biotin-requiring enzyme 535 600 1.5E-17 T 14-10-2018 IPR000089 Biotin/lipoyl attachment MB46_02790 fc12ff8b921f6afc1094e9db2945ac89 602 Pfam PF02785 Biotin carboxylase C-terminal domain 347 458 3.0E-35 T 14-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MB46_02790 fc12ff8b921f6afc1094e9db2945ac89 602 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 557 574 - T 14-10-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MB46_02790 fc12ff8b921f6afc1094e9db2945ac89 602 SMART SM00878 347 458 3.7E-56 T 14-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MB46_02790 fc12ff8b921f6afc1094e9db2945ac89 602 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 334 2.7E-74 T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MB46_06080 a333184f69cea4b28caef226b09d5295 301 Gene3D G3DSA:1.10.260.40 13 84 1.7E-5 T 14-10-2018 MB46_06080 a333184f69cea4b28caef226b09d5295 301 Pfam PF13560 Helix-turn-helix domain 12 85 6.1E-13 T 14-10-2018 MB46_06080 a333184f69cea4b28caef226b09d5295 301 Gene3D G3DSA:3.30.450.180 110 281 7.5E-16 T 14-10-2018 MB46_06080 a333184f69cea4b28caef226b09d5295 301 SUPERFAMILY SSF47413 29 80 1.23E-6 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MB46_06080 a333184f69cea4b28caef226b09d5295 301 SMART SM00530 10 82 1.1E-4 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MB46_00925 f4e0d7e2a37f4fc974ecf916c4b51394 334 Hamap MF_00042 Ribonuclease H [rnhA]. 1 147 25.262 T 14-10-2018 IPR022892 Ribonuclease HI GO:0004523 MB46_00925 f4e0d7e2a37f4fc974ecf916c4b51394 334 Gene3D G3DSA:3.30.420.10 1 151 4.2E-44 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 MB46_00925 f4e0d7e2a37f4fc974ecf916c4b51394 334 Pfam PF00075 RNase H 6 138 1.1E-26 T 14-10-2018 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 MB46_00925 f4e0d7e2a37f4fc974ecf916c4b51394 334 Pfam PF14534 Domain of unknown function (DUF4440) 229 325 1.8E-12 T 14-10-2018 IPR027843 Domain of unknown function DUF4440 MB46_00925 f4e0d7e2a37f4fc974ecf916c4b51394 334 SUPERFAMILY SSF54427 222 331 2.07E-16 T 14-10-2018 IPR032710 NTF2-like domain superfamily MB46_00925 f4e0d7e2a37f4fc974ecf916c4b51394 334 Gene3D G3DSA:3.10.450.50 219 332 1.6E-12 T 14-10-2018 MB46_00925 f4e0d7e2a37f4fc974ecf916c4b51394 334 SUPERFAMILY SSF53098 3 140 2.15E-39 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily MB46_03295 a0af0922636757e8bbb01d3b730a7bec 424 SMART SM00471 60 226 5.5E-13 T 14-10-2018 IPR003607 HD/PDEase domain MB46_03295 a0af0922636757e8bbb01d3b730a7bec 424 SUPERFAMILY SSF109604 24 411 5.71E-57 T 14-10-2018 MB46_03295 a0af0922636757e8bbb01d3b730a7bec 424 TIGRFAM TIGR01353 dGTP_triPase: putative dGTPase 27 417 4.4E-84 T 14-10-2018 IPR006261 dNTP triphosphohydrolase GO:0016793 MB46_03295 a0af0922636757e8bbb01d3b730a7bec 424 Pfam PF13286 Phosphohydrolase-associated domain 323 415 1.0E-20 T 14-10-2018 IPR026875 Phosphohydrolase-associated domain MB46_03295 a0af0922636757e8bbb01d3b730a7bec 424 Pfam PF01966 HD domain 64 215 6.0E-19 T 14-10-2018 IPR006674 HD domain MB46_03295 a0af0922636757e8bbb01d3b730a7bec 424 Gene3D G3DSA:1.10.3210.10 4 418 5.0E-91 T 14-10-2018 MB46_03295 a0af0922636757e8bbb01d3b730a7bec 424 Hamap MF_01212 Deoxyguanosinetriphosphate triphosphohydrolase-like protein. 3 417 30.095 T 14-10-2018 IPR023023 dNTP triphosphohydrolase, type 2 GO:0016793 MB46_11040 64babfa803487eaca71ed3a1e22e231e 281 SUPERFAMILY SSF52821 4 148 7.2E-38 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily MB46_11040 64babfa803487eaca71ed3a1e22e231e 281 Pfam PF00581 Rhodanese-like domain 160 264 2.2E-10 T 14-10-2018 IPR001763 Rhodanese-like domain MB46_11040 64babfa803487eaca71ed3a1e22e231e 281 Pfam PF00581 Rhodanese-like domain 9 127 1.3E-18 T 14-10-2018 IPR001763 Rhodanese-like domain MB46_11040 64babfa803487eaca71ed3a1e22e231e 281 SUPERFAMILY SSF52821 154 274 1.7E-31 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily MB46_11040 64babfa803487eaca71ed3a1e22e231e 281 ProSitePatterns PS00380 Rhodanese signature 1. 38 49 - T 14-10-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350|MetaCyc: PWY-7927|Reactome: R-HSA-1614558 MB46_11040 64babfa803487eaca71ed3a1e22e231e 281 Gene3D G3DSA:3.40.250.10 152 279 1.8E-32 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily MB46_11040 64babfa803487eaca71ed3a1e22e231e 281 Gene3D G3DSA:3.40.250.10 1 148 6.3E-44 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily MB46_11040 64babfa803487eaca71ed3a1e22e231e 281 SMART SM00450 5 131 1.3E-25 T 14-10-2018 IPR001763 Rhodanese-like domain MB46_11040 64babfa803487eaca71ed3a1e22e231e 281 SMART SM00450 150 268 2.2E-12 T 14-10-2018 IPR001763 Rhodanese-like domain MB46_03010 55b28e1350a33ef9be4ad9c67a2e8e1c 451 SUPERFAMILY SSF89796 18 176 6.28E-23 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily MB46_03010 55b28e1350a33ef9be4ad9c67a2e8e1c 451 SUPERFAMILY SSF89796 195 390 1.96E-53 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily MB46_03010 55b28e1350a33ef9be4ad9c67a2e8e1c 451 Pfam PF02515 CoA-transferase family III 197 391 3.3E-44 T 14-10-2018 IPR003673 CoA-transferase family III GO:0003824 MB46_03010 55b28e1350a33ef9be4ad9c67a2e8e1c 451 Gene3D G3DSA:3.40.50.10540 192 410 2.6E-52 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily MB46_15060 e99559a71b021b89532450fd6412bf0d 429 Gene3D G3DSA:3.40.190.10 161 420 2.7E-94 T 14-10-2018 MB46_15060 e99559a71b021b89532450fd6412bf0d 429 Gene3D G3DSA:3.40.190.10 66 381 2.7E-94 T 14-10-2018 MB46_15060 e99559a71b021b89532450fd6412bf0d 429 Pfam PF01547 Bacterial extracellular solute-binding protein 62 344 5.3E-35 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein MB46_15060 e99559a71b021b89532450fd6412bf0d 429 SUPERFAMILY SSF53850 53 423 5.69E-86 T 14-10-2018 MB46_15830 6583cf3ab2811d7b7ebcfa98821ac970 367 Pfam PF07510 Protein of unknown function (DUF1524) 128 267 7.1E-20 T 14-10-2018 IPR011089 Domain of unknown function DUF1524 MB46_15830 6583cf3ab2811d7b7ebcfa98821ac970 367 Pfam PF05901 Excalibur calcium-binding domain 332 367 5.9E-12 T 14-10-2018 IPR008613 Excalibur calcium-binding domain MB46_15830 6583cf3ab2811d7b7ebcfa98821ac970 367 SMART SM00894 331 367 4.4E-18 T 14-10-2018 IPR008613 Excalibur calcium-binding domain MB46_16825 c81a0799c856afab89d07fcea063f522 238 SUPERFAMILY SSF51735 4 198 3.02E-31 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_16825 c81a0799c856afab89d07fcea063f522 238 Gene3D G3DSA:3.40.50.720 1 197 2.1E-45 T 14-10-2018 MB46_16825 c81a0799c856afab89d07fcea063f522 238 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 4 91 8.5E-19 T 14-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal MB46_00815 548d2ab261926fe0d56881b609116c77 250 SUPERFAMILY SSF51735 9 249 3.71E-67 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_00815 548d2ab261926fe0d56881b609116c77 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 146 165 9.8E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_00815 548d2ab261926fe0d56881b609116c77 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 73 84 9.8E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_00815 548d2ab261926fe0d56881b609116c77 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 184 9.8E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_00815 548d2ab261926fe0d56881b609116c77 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 232 9.8E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_00815 548d2ab261926fe0d56881b609116c77 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 9.8E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_00815 548d2ab261926fe0d56881b609116c77 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 120 136 9.8E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_00815 548d2ab261926fe0d56881b609116c77 250 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 248 8.1E-47 T 14-10-2018 MB46_00815 548d2ab261926fe0d56881b609116c77 250 Gene3D G3DSA:3.40.50.720 4 250 1.9E-71 T 14-10-2018 MB46_00815 548d2ab261926fe0d56881b609116c77 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 146 165 1.1E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_00815 548d2ab261926fe0d56881b609116c77 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 126 134 1.1E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_00815 548d2ab261926fe0d56881b609116c77 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 73 84 1.1E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_00815 548d2ab261926fe0d56881b609116c77 250 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 133 161 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MB46_15525 1fe07735c54b8e4e6dc054f239f709a7 369 SUPERFAMILY SSF53448 3 219 1.31E-14 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MB46_15525 1fe07735c54b8e4e6dc054f239f709a7 369 Pfam PF04138 GtrA-like protein 221 335 1.6E-11 T 14-10-2018 IPR007267 GtrA-like protein GO:0000271|GO:0016021 MB46_15525 1fe07735c54b8e4e6dc054f239f709a7 369 Gene3D G3DSA:3.90.550.10 1 227 1.2E-19 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MB46_15525 1fe07735c54b8e4e6dc054f239f709a7 369 Pfam PF00535 Glycosyl transferase family 2 3 129 6.9E-10 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MB46_01535 343fc76d94f2398b19071ed77bf9b98c 306 Gene3D G3DSA:3.50.50.60 3 290 1.7E-90 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_01535 343fc76d94f2398b19071ed77bf9b98c 306 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 276 1.7E-25 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MB46_01535 343fc76d94f2398b19071ed77bf9b98c 306 SUPERFAMILY SSF51905 1 290 6.48E-36 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_01535 343fc76d94f2398b19071ed77bf9b98c 306 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 3 25 5.2E-18 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MB46_01535 343fc76d94f2398b19071ed77bf9b98c 306 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 258 276 5.2E-18 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MB46_01535 343fc76d94f2398b19071ed77bf9b98c 306 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 100 108 5.2E-18 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MB46_01535 343fc76d94f2398b19071ed77bf9b98c 306 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 122 134 5.2E-18 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MB46_01535 343fc76d94f2398b19071ed77bf9b98c 306 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 137 161 5.2E-18 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MB46_01535 343fc76d94f2398b19071ed77bf9b98c 306 Gene3D G3DSA:3.50.50.60 113 224 1.7E-90 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_01535 343fc76d94f2398b19071ed77bf9b98c 306 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 6.8E-17 T 14-10-2018 MB46_01535 343fc76d94f2398b19071ed77bf9b98c 306 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 141 159 6.8E-17 T 14-10-2018 MB46_01535 343fc76d94f2398b19071ed77bf9b98c 306 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 99 117 6.8E-17 T 14-10-2018 MB46_01535 343fc76d94f2398b19071ed77bf9b98c 306 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 248 270 6.8E-17 T 14-10-2018 MB46_07070 62b65bcc5dbe45152d14108275badefe 234 Gene3D G3DSA:1.10.10.10 2 76 1.2E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_07070 62b65bcc5dbe45152d14108275badefe 234 Pfam PF07729 FCD domain 88 209 2.4E-24 T 14-10-2018 IPR011711 GntR, C-terminal MB46_07070 62b65bcc5dbe45152d14108275badefe 234 Gene3D G3DSA:1.20.120.530 81 224 4.9E-23 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MB46_07070 62b65bcc5dbe45152d14108275badefe 234 SUPERFAMILY SSF48008 88 216 1.12E-19 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MB46_07070 62b65bcc5dbe45152d14108275badefe 234 SUPERFAMILY SSF46785 9 79 9.37E-17 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_07070 62b65bcc5dbe45152d14108275badefe 234 SMART SM00345 17 75 2.9E-9 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MB46_07070 62b65bcc5dbe45152d14108275badefe 234 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 75 6.6E-15 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MB46_07070 62b65bcc5dbe45152d14108275badefe 234 SMART SM00895 85 211 3.8E-9 T 14-10-2018 IPR011711 GntR, C-terminal MB46_11185 62b400dabfb11e41382b76a8e8409f08 282 SUPERFAMILY SSF51658 26 254 1.66E-35 T 14-10-2018 IPR036237 Xylose isomerase-like superfamily MB46_11185 62b400dabfb11e41382b76a8e8409f08 282 Pfam PF01261 Xylose isomerase-like TIM barrel 30 223 7.5E-25 T 14-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain MB46_11185 62b400dabfb11e41382b76a8e8409f08 282 Gene3D G3DSA:3.20.20.150 22 272 2.8E-44 T 14-10-2018 MB46_06305 e2fce6323e3b699d64485cd02530be89 132 Gene3D G3DSA:3.90.15.10 82 124 9.0E-6 T 14-10-2018 IPR014711 DNA topoisomerase I, catalytic core, alpha-helical subdomain, eukaryotic-type GO:0003677|GO:0003917|GO:0006265 MB46_06305 e2fce6323e3b699d64485cd02530be89 132 SUPERFAMILY SSF55869 43 76 2.62E-10 T 14-10-2018 IPR035447 DNA topoisomerase I, N-terminal MB46_06305 e2fce6323e3b699d64485cd02530be89 132 SUPERFAMILY SSF56349 71 117 2.94E-6 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MB46_06305 e2fce6323e3b699d64485cd02530be89 132 Gene3D G3DSA:3.30.66.10 41 81 5.0E-13 T 14-10-2018 IPR035447 DNA topoisomerase I, N-terminal MB46_19415 71856f42a86232ea40b7bb2a68d0355d 308 SUPERFAMILY SSF63817 112 251 4.45E-42 T 14-10-2018 IPR023365 Sortase domain superfamily MB46_19415 71856f42a86232ea40b7bb2a68d0355d 308 Pfam PF04203 Sortase family 125 250 2.1E-22 T 14-10-2018 IPR005754 Sortase family MB46_19415 71856f42a86232ea40b7bb2a68d0355d 308 TIGRFAM TIGR01076 sortase_fam: sortase 123 252 7.6E-45 T 14-10-2018 IPR005754 Sortase family MB46_19415 71856f42a86232ea40b7bb2a68d0355d 308 Gene3D G3DSA:2.40.260.10 47 260 3.0E-60 T 14-10-2018 IPR023365 Sortase domain superfamily MB46_11720 1902fee0c0a8a6a4840230f8e492c177 406 Pfam PF00266 Aminotransferase class-V 3 377 6.4E-59 T 14-10-2018 IPR000192 Aminotransferase class V domain MB46_11720 1902fee0c0a8a6a4840230f8e492c177 406 PIRSF PIRSF005572 1 391 8.2E-110 T 14-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 MB46_11720 1902fee0c0a8a6a4840230f8e492c177 406 Gene3D G3DSA:3.40.640.10 14 262 8.9E-132 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MB46_11720 1902fee0c0a8a6a4840230f8e492c177 406 SUPERFAMILY SSF53383 3 384 2.93E-90 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MB46_11720 1902fee0c0a8a6a4840230f8e492c177 406 Gene3D G3DSA:3.90.1150.10 4 379 8.9E-132 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MB46_15930 3075b5a5fd03fa5feb4844fc86807a56 393 TIGRFAM TIGR03364 HpnW_proposed: FAD dependent oxidoreductase TIGR03364 11 377 1.3E-118 T 14-10-2018 IPR017741 FAD-dependent oxidoreductase, HpnW MB46_15930 3075b5a5fd03fa5feb4844fc86807a56 393 SUPERFAMILY SSF51905 10 383 6.99E-30 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_15930 3075b5a5fd03fa5feb4844fc86807a56 393 Pfam PF01266 FAD dependent oxidoreductase 12 380 1.3E-27 T 14-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 MB46_09935 8483f20454099cf708fb864e314e476a 199 SUPERFAMILY SSF52016 1 188 2.94E-51 T 14-10-2018 MB46_09935 8483f20454099cf708fb864e314e476a 199 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 1 180 1.2E-54 T 14-10-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 MB46_09935 8483f20454099cf708fb864e314e476a 199 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 1 191 37.482 T 14-10-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 MB46_09935 8483f20454099cf708fb864e314e476a 199 Gene3D G3DSA:3.20.19.10 1 168 4.9E-65 T 14-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 MB46_09935 8483f20454099cf708fb864e314e476a 199 Pfam PF00694 Aconitase C-terminal domain 1 116 6.7E-25 T 14-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 MB46_04585 160ae09a755d8c723b90bbea8ae7dfe8 183 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 75 173 1.9E-8 T 14-10-2018 IPR003477 mRNA interferase PemK-like GO:0003677 MB46_04585 160ae09a755d8c723b90bbea8ae7dfe8 183 SUPERFAMILY SSF50118 73 173 8.72E-8 T 14-10-2018 MB46_00610 18f9876345164573d122629d2d264be2 408 SUPERFAMILY SSF50969 55 403 3.14E-15 T 14-10-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like MB46_00610 18f9876345164573d122629d2d264be2 408 Gene3D G3DSA:2.130.10.10 221 404 2.5E-8 T 14-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 MB46_04070 9bf328e63aee96c0ded6f6f4fabaf93a 163 Pfam PF10517 Electron transfer DM13 54 160 4.3E-10 T 14-10-2018 IPR019545 DM13 domain MB46_11855 54bc4a813b4ac5569d89ae7933a59ec6 330 Pfam PF12697 Alpha/beta hydrolase family 81 308 6.6E-10 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MB46_11855 54bc4a813b4ac5569d89ae7933a59ec6 330 Gene3D G3DSA:3.40.50.1820 62 325 1.3E-35 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_11855 54bc4a813b4ac5569d89ae7933a59ec6 330 SUPERFAMILY SSF53474 60 324 5.59E-28 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_12845 dd9d29e3ee65705cd85e00559e8fb51d 419 Gene3D G3DSA:1.20.1250.20 28 410 4.4E-31 T 14-10-2018 MB46_12845 dd9d29e3ee65705cd85e00559e8fb51d 419 Pfam PF07690 Major Facilitator Superfamily 31 366 4.6E-22 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MB46_12845 dd9d29e3ee65705cd85e00559e8fb51d 419 SUPERFAMILY SSF103473 29 411 8.11E-31 T 14-10-2018 IPR036259 MFS transporter superfamily MB46_03970 38d4782f5d58feb995862ae4a03ca1db 206 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 39 186 2.3E-57 T 14-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 MB46_03970 38d4782f5d58feb995862ae4a03ca1db 206 Gene3D G3DSA:3.30.230.40 1 97 1.5E-34 T 14-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 MB46_03970 38d4782f5d58feb995862ae4a03ca1db 206 Gene3D G3DSA:3.30.230.40 98 206 8.0E-35 T 14-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 MB46_03970 38d4782f5d58feb995862ae4a03ca1db 206 SUPERFAMILY SSF54211 10 93 3.79E-31 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MB46_03970 38d4782f5d58feb995862ae4a03ca1db 206 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 168 180 - T 14-10-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 MB46_03970 38d4782f5d58feb995862ae4a03ca1db 206 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 10 206 40.231 T 14-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 MB46_03970 38d4782f5d58feb995862ae4a03ca1db 206 SUPERFAMILY SSF54211 95 191 8.85E-28 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MB46_03970 38d4782f5d58feb995862ae4a03ca1db 206 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 69 82 - T 14-10-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 MB46_14630 217bb4dd2a4ae1117ba50083f02d31c8 398 Gene3D G3DSA:1.20.1250.20 1 176 1.3E-14 T 14-10-2018 MB46_14630 217bb4dd2a4ae1117ba50083f02d31c8 398 SUPERFAMILY SSF103473 7 387 2.49E-40 T 14-10-2018 IPR036259 MFS transporter superfamily MB46_14630 217bb4dd2a4ae1117ba50083f02d31c8 398 Gene3D G3DSA:1.20.1250.20 208 393 1.5E-15 T 14-10-2018 MB46_14630 217bb4dd2a4ae1117ba50083f02d31c8 398 Pfam PF07690 Major Facilitator Superfamily 7 353 1.2E-21 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MB46_06210 4947b7308fc56c2fb72bfd0418bd5ad5 445 Gene3D G3DSA:3.40.190.10 160 432 1.3E-48 T 14-10-2018 MB46_06210 4947b7308fc56c2fb72bfd0418bd5ad5 445 Pfam PF13416 Bacterial extracellular solute-binding protein 78 376 8.2E-19 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein MB46_06210 4947b7308fc56c2fb72bfd0418bd5ad5 445 Gene3D G3DSA:3.40.190.10 78 372 1.3E-48 T 14-10-2018 MB46_06210 4947b7308fc56c2fb72bfd0418bd5ad5 445 SUPERFAMILY SSF53850 47 437 7.03E-43 T 14-10-2018 MB46_00865 6f8167a619a96610e4c17489e931dd66 209 ProSitePatterns PS01081 TetR-type HTH domain signature. 32 63 - T 14-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site MB46_00865 6f8167a619a96610e4c17489e931dd66 209 SUPERFAMILY SSF46689 7 63 5.67E-12 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MB46_00865 6f8167a619a96610e4c17489e931dd66 209 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 61 1.2E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MB46_00865 6f8167a619a96610e4c17489e931dd66 209 Gene3D G3DSA:1.10.357.10 5 207 8.3E-28 T 14-10-2018 MB46_02125 b633a4c48f326134896728892b767390 215 Pfam PF03006 Haemolysin-III related 8 206 1.9E-35 T 14-10-2018 IPR004254 AdipoR/Haemolysin-III-related GO:0016021 MB46_17700 516b2ab2865d88283b5912227f192fe8 322 Pfam PF14100 Methane oxygenase PmoA 25 306 3.6E-73 T 14-10-2018 IPR029475 Methane oxygenase PmoA MB46_00670 49a6a54280425d7c5708c1178f922d0f 359 Pfam PF09949 Uncharacterized conserved protein (DUF2183) 218 313 5.4E-28 T 14-10-2018 IPR019236 Domain of unknown function DUF2183 MB46_03625 85a111e240dff2f2a6915502ce2c765d 191 Pfam PF03358 NADPH-dependent FMN reductase 2 140 4.2E-28 T 14-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 MB46_03625 85a111e240dff2f2a6915502ce2c765d 191 SUPERFAMILY SSF52218 1 146 8.89E-31 T 14-10-2018 IPR029039 Flavoprotein-like superfamily MB46_03625 85a111e240dff2f2a6915502ce2c765d 191 Gene3D G3DSA:3.40.50.360 1 190 1.2E-39 T 14-10-2018 IPR029039 Flavoprotein-like superfamily MB46_01340 e6f6ca8d7c76e6424ccb47f9516166d9 604 SUPERFAMILY SSF50249 217 308 3.62E-7 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold MB46_01340 e6f6ca8d7c76e6424ccb47f9516166d9 604 Gene3D G3DSA:2.40.50.140 226 305 2.3E-5 T 14-10-2018 MB46_06025 ae2aa52f9d81fc438ee69c8443e8cb98 400 SUPERFAMILY SSF55347 143 319 1.96E-33 T 14-10-2018 MB46_06025 ae2aa52f9d81fc438ee69c8443e8cb98 400 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 8 128 5.6E-26 T 14-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 MB46_06025 ae2aa52f9d81fc438ee69c8443e8cb98 400 Gene3D G3DSA:3.40.50.720 3 141 7.1E-41 T 14-10-2018 MB46_06025 ae2aa52f9d81fc438ee69c8443e8cb98 400 Gene3D G3DSA:3.30.360.10 143 394 9.3E-69 T 14-10-2018 MB46_06025 ae2aa52f9d81fc438ee69c8443e8cb98 400 SUPERFAMILY SSF51735 7 169 4.35E-45 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_06025 ae2aa52f9d81fc438ee69c8443e8cb98 400 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 149 219 2.5E-10 T 14-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 MB46_03370 b0e050a8e4954356ed2af6a112472c44 299 Pfam PF05653 Magnesium transporter NIPA 4 168 8.7E-10 T 14-10-2018 IPR008521 Magnesium transporter NIPA GO:0015095|GO:0015693|GO:0016021 Reactome: R-HSA-5223345 MB46_18955 ab1ec5d66e1799ba2b6ce01ab0f54beb 755 Pfam PF02554 Carbon starvation protein CstA 67 444 7.3E-162 T 14-10-2018 IPR003706 CstA, N-terminal domain GO:0009267|GO:0016020 MB46_18955 ab1ec5d66e1799ba2b6ce01ab0f54beb 755 Pfam PF13722 5TM C-terminal transporter carbon starvation CstA 502 630 4.8E-32 T 14-10-2018 IPR025299 CstA, C-terminal domain MB46_16605 b730ecdf88fceadaba6b238741882743 128 SUPERFAMILY SSF46955 70 120 3.39E-7 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily MB46_16605 b730ecdf88fceadaba6b238741882743 128 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 70 118 6.9E-10 T 14-10-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 MB46_16605 b730ecdf88fceadaba6b238741882743 128 Pfam PF12728 Helix-turn-helix domain 70 119 2.4E-12 T 14-10-2018 MB46_05075 e785bd3f6b2378fcc7881b23614608c4 84 Pfam PF03840 Preprotein translocase SecG subunit 8 76 2.2E-16 T 14-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 MB46_05075 e785bd3f6b2378fcc7881b23614608c4 84 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 6 76 3.6E-17 T 14-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 MB46_05075 e785bd3f6b2378fcc7881b23614608c4 84 PRINTS PR01651 Protein-export SecG membrane protein signature 6 26 3.4E-5 T 14-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 MB46_05075 e785bd3f6b2378fcc7881b23614608c4 84 PRINTS PR01651 Protein-export SecG membrane protein signature 26 40 3.4E-5 T 14-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 MB46_05075 e785bd3f6b2378fcc7881b23614608c4 84 PRINTS PR01651 Protein-export SecG membrane protein signature 57 79 3.4E-5 T 14-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 MB46_02335 9a4a58c86374176be4d1c17af7846492 399 Gene3D G3DSA:3.40.50.300 142 380 1.1E-52 T 14-10-2018 MB46_02335 9a4a58c86374176be4d1c17af7846492 399 SUPERFAMILY SSF52540 144 380 1.21E-40 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_02335 9a4a58c86374176be4d1c17af7846492 399 Pfam PF13614 AAA domain 144 299 5.0E-16 T 14-10-2018 IPR025669 AAA domain MB46_08700 34e1be43d659c084072daa5d2c7f0ac4 185 Gene3D G3DSA:3.40.630.30 4 174 1.2E-16 T 14-10-2018 MB46_08700 34e1be43d659c084072daa5d2c7f0ac4 185 SUPERFAMILY SSF55729 71 181 6.75E-19 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase MB46_08700 34e1be43d659c084072daa5d2c7f0ac4 185 Pfam PF00583 Acetyltransferase (GNAT) family 83 168 6.8E-12 T 14-10-2018 IPR000182 GNAT domain MB46_19545 ec0e62d7c77b47bdd9ff9bfa0cdae23b 281 Pfam PF04542 Sigma-70 region 2 19 79 3.0E-12 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 MB46_19545 ec0e62d7c77b47bdd9ff9bfa0cdae23b 281 Gene3D G3DSA:1.10.1740.10 10 79 5.0E-10 T 14-10-2018 MB46_19545 ec0e62d7c77b47bdd9ff9bfa0cdae23b 281 SUPERFAMILY SSF88946 20 79 3.14E-10 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 MB46_07660 08914730bee998d17d51e8c04cb92f49 138 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 75 124 3.0E-21 T 14-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 MB46_07660 08914730bee998d17d51e8c04cb92f49 138 Gene3D G3DSA:3.10.20.400 20 116 2.4E-38 T 14-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 MB46_07660 08914730bee998d17d51e8c04cb92f49 138 SUPERFAMILY SSF141734 28 127 3.66E-44 T 14-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 MB46_07660 08914730bee998d17d51e8c04cb92f49 138 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 26 129 29.805 T 14-10-2018 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 MB46_07660 08914730bee998d17d51e8c04cb92f49 138 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 52 124 7.0E-33 T 14-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 MB46_16280 467109007e169074adcd8682ee35bcc8 1098 Pfam PF13558 Putative exonuclease SbcCD, C subunit 958 1044 6.2E-14 T 14-10-2018 MB46_16280 467109007e169074adcd8682ee35bcc8 1098 SUPERFAMILY SSF52540 19 1053 9.18E-6 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_16280 467109007e169074adcd8682ee35bcc8 1098 Gene3D G3DSA:3.40.1140.10 16 117 4.8E-5 T 14-10-2018 MB46_16280 467109007e169074adcd8682ee35bcc8 1098 Pfam PF13555 P-loop containing region of AAA domain 20 77 2.9E-17 T 14-10-2018 MB46_06815 e1253d1ec372f5e2e08e3b4dd388cff4 421 ProSitePatterns PS00217 Sugar transport proteins signature 2. 118 143 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MB46_06815 e1253d1ec372f5e2e08e3b4dd388cff4 421 Gene3D G3DSA:1.20.1250.20 17 412 1.6E-60 T 14-10-2018 MB46_06815 e1253d1ec372f5e2e08e3b4dd388cff4 421 Pfam PF07690 Major Facilitator Superfamily 30 362 1.8E-37 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MB46_06815 e1253d1ec372f5e2e08e3b4dd388cff4 421 ProSitePatterns PS00216 Sugar transport proteins signature 1. 76 93 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MB46_06815 e1253d1ec372f5e2e08e3b4dd388cff4 421 SUPERFAMILY SSF103473 5 399 8.63E-68 T 14-10-2018 IPR036259 MFS transporter superfamily MB46_08750 e9311ba69c2786d92dcd469fc930e1bd 235 Gene3D G3DSA:3.90.1680.10 1 233 1.3E-62 T 14-10-2018 IPR036590 SOS response associated peptidase-like MB46_08750 e9311ba69c2786d92dcd469fc930e1bd 235 Pfam PF02586 SOS response associated peptidase (SRAP) 7 222 5.6E-58 T 14-10-2018 IPR003738 SOS response associated peptidase (SRAP) MB46_08750 e9311ba69c2786d92dcd469fc930e1bd 235 SUPERFAMILY SSF143081 17 233 2.75E-57 T 14-10-2018 IPR036590 SOS response associated peptidase-like MB46_13090 8d7fa85637c843ec232cd12f066ea4a8 380 SUPERFAMILY SSF55931 3 377 2.75E-109 T 14-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 MB46_13090 8d7fa85637c843ec232cd12f066ea4a8 380 TIGRFAM TIGR02050 gshA_cyan_rel: carboxylate-amine ligase, YbdK family 12 305 4.3E-101 T 14-10-2018 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 MB46_13090 8d7fa85637c843ec232cd12f066ea4a8 380 Hamap MF_01609 Glutamate--cysteine ligase [gshA]. 1 380 97.217 T 14-10-2018 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 MB46_13090 8d7fa85637c843ec232cd12f066ea4a8 380 Gene3D G3DSA:3.30.590.20 2 380 1.0E-103 T 14-10-2018 MB46_13090 8d7fa85637c843ec232cd12f066ea4a8 380 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 13 299 1.3E-65 T 14-10-2018 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 MB46_16885 f9ac057566193f333ac8c07592b94e65 446 SUPERFAMILY SSF103473 38 422 1.57E-45 T 14-10-2018 IPR036259 MFS transporter superfamily MB46_16885 f9ac057566193f333ac8c07592b94e65 446 Pfam PF05977 Transmembrane secretion effector 30 420 9.3E-47 T 14-10-2018 IPR010290 Transmembrane secretion effector MB46_16885 f9ac057566193f333ac8c07592b94e65 446 Gene3D G3DSA:1.20.1250.20 34 419 6.0E-38 T 14-10-2018 MB46_06220 7589a38998d54fc4ce02670987f0049e 299 SUPERFAMILY SSF161098 30 299 3.14E-64 T 14-10-2018 IPR035906 MetI-like superfamily MB46_06220 7589a38998d54fc4ce02670987f0049e 299 Gene3D G3DSA:1.10.3720.10 28 289 1.6E-57 T 14-10-2018 IPR035906 MetI-like superfamily MB46_06220 7589a38998d54fc4ce02670987f0049e 299 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 115 283 1.5E-14 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_17795 b8821da2a6fe71fef8ed95aa64d7fd1a 466 Pfam PF00743 Flavin-binding monooxygenase-like 4 231 8.8E-29 T 14-10-2018 IPR020946 Flavin monooxygenase-like GO:0004499|GO:0050660|GO:0050661|GO:0055114 MB46_17795 b8821da2a6fe71fef8ed95aa64d7fd1a 466 Pfam PF00743 Flavin-binding monooxygenase-like 244 379 3.1E-9 T 14-10-2018 IPR020946 Flavin monooxygenase-like GO:0004499|GO:0050660|GO:0050661|GO:0055114 MB46_17795 b8821da2a6fe71fef8ed95aa64d7fd1a 466 Gene3D G3DSA:3.50.50.60 173 272 4.6E-159 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_17795 b8821da2a6fe71fef8ed95aa64d7fd1a 466 SUPERFAMILY SSF51905 252 387 1.12E-9 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_17795 b8821da2a6fe71fef8ed95aa64d7fd1a 466 SUPERFAMILY SSF51905 1 237 1.26E-43 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_17795 b8821da2a6fe71fef8ed95aa64d7fd1a 466 PIRSF PIRSF000332 1 236 5.8E-31 T 14-10-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 MB46_17795 b8821da2a6fe71fef8ed95aa64d7fd1a 466 PIRSF PIRSF000332 240 402 9.2E-12 T 14-10-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 MB46_17795 b8821da2a6fe71fef8ed95aa64d7fd1a 466 Gene3D G3DSA:3.50.50.60 4 415 4.6E-159 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_01635 bb5879f47c0816c5cd94833ccda2e93d 305 PIRSF PIRSF028757 6 304 3.7E-56 T 14-10-2018 IPR003507 Peptidase family S66 MB46_01635 bb5879f47c0816c5cd94833ccda2e93d 305 SUPERFAMILY SSF52317 5 163 7.78E-36 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like MB46_01635 bb5879f47c0816c5cd94833ccda2e93d 305 Pfam PF02016 LD-carboxypeptidase 16 294 1.0E-57 T 14-10-2018 IPR003507 Peptidase family S66 MB46_01635 bb5879f47c0816c5cd94833ccda2e93d 305 Gene3D G3DSA:3.40.50.10740 6 164 4.0E-42 T 14-10-2018 IPR027478 Murein tetrapeptide carboxypeptidase, N-terminal MB46_01635 bb5879f47c0816c5cd94833ccda2e93d 305 SUPERFAMILY SSF141986 156 298 9.68E-28 T 14-10-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain superfamily MB46_01635 bb5879f47c0816c5cd94833ccda2e93d 305 Gene3D G3DSA:3.50.30.60 170 299 9.0E-31 T 14-10-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain superfamily MB46_15225 1462072cb73bd4798c1639379ecde3a4 615 Gene3D G3DSA:1.50.10.10 222 603 1.9E-88 T 14-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 MB46_15225 1462072cb73bd4798c1639379ecde3a4 615 Pfam PF00723 Glycosyl hydrolases family 15 546 587 1.2E-5 T 14-10-2018 IPR011613 GH15-like domain Reactome: R-HSA-70221 MB46_15225 1462072cb73bd4798c1639379ecde3a4 615 Pfam PF00723 Glycosyl hydrolases family 15 225 535 3.0E-48 T 14-10-2018 IPR011613 GH15-like domain Reactome: R-HSA-70221 MB46_15225 1462072cb73bd4798c1639379ecde3a4 615 SUPERFAMILY SSF48208 196 593 4.42E-98 T 14-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 MB46_01990 ef47668f11c45956827a8a1f974cc166 163 Pfam PF16571 FBP C-terminal treble-clef zinc-finger 8 161 7.6E-58 T 14-10-2018 IPR032330 Elongation factor G-binding protein, C-terminal treble-clef zinc-finger MB46_17060 11ffe5d58e6eadb810d7c99370b1e555 206 Pfam PF01810 LysE type translocator 15 205 5.3E-36 T 14-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 MB46_17060 11ffe5d58e6eadb810d7c99370b1e555 206 PIRSF PIRSF006324 1 206 1.1E-53 T 14-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 MB46_15925 ecb757a03a6febe9fdf60e95fcb650ef 250 Gene3D G3DSA:1.10.10.10 2 75 7.5E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_15925 ecb757a03a6febe9fdf60e95fcb650ef 250 Pfam PF00392 Bacterial regulatory proteins, gntR family 7 63 2.5E-12 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MB46_15925 ecb757a03a6febe9fdf60e95fcb650ef 250 Gene3D G3DSA:3.40.1410.10 76 234 1.3E-37 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily MB46_15925 ecb757a03a6febe9fdf60e95fcb650ef 250 SUPERFAMILY SSF64288 56 231 1.88E-38 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily MB46_15925 ecb757a03a6febe9fdf60e95fcb650ef 250 Pfam PF07702 UTRA domain 90 225 1.8E-31 T 14-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 MB46_15925 ecb757a03a6febe9fdf60e95fcb650ef 250 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 28 42 1.8E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MB46_15925 ecb757a03a6febe9fdf60e95fcb650ef 250 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 42 58 1.8E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MB46_15925 ecb757a03a6febe9fdf60e95fcb650ef 250 SMART SM00866 89 228 2.6E-29 T 14-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 MB46_15925 ecb757a03a6febe9fdf60e95fcb650ef 250 SUPERFAMILY SSF46785 5 70 5.21E-14 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_15925 ecb757a03a6febe9fdf60e95fcb650ef 250 SMART SM00345 9 68 4.6E-10 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MB46_16015 6eca40d71b6278a595d349f97c0a265b 207 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 20 206 2.0E-47 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MB46_16015 6eca40d71b6278a595d349f97c0a265b 207 SMART SM00855 19 168 9.5E-23 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MB46_16015 6eca40d71b6278a595d349f97c0a265b 207 Gene3D G3DSA:3.40.50.1240 16 207 2.3E-50 T 14-10-2018 IPR029033 Histidine phosphatase superfamily MB46_16015 6eca40d71b6278a595d349f97c0a265b 207 PIRSF PIRSF000709 131 192 3.5 T 14-10-2018 MB46_16015 6eca40d71b6278a595d349f97c0a265b 207 PIRSF PIRSF000709 18 117 4.8E-4 T 14-10-2018 MB46_16015 6eca40d71b6278a595d349f97c0a265b 207 SUPERFAMILY SSF53254 19 204 2.78E-47 T 14-10-2018 IPR029033 Histidine phosphatase superfamily MB46_01115 14499f0e435d870ec7f513469f4b8a04 370 Pfam PF03641 Possible lysine decarboxylase 248 366 1.2E-6 T 14-10-2018 IPR031100 LOG family MB46_01115 14499f0e435d870ec7f513469f4b8a04 370 SUPERFAMILY SSF102405 146 368 1.37E-25 T 14-10-2018 MB46_06155 45f0a6003dc615e30890be672663ddb7 260 Pfam PF13460 NAD(P)H-binding 18 197 6.3E-35 T 14-10-2018 IPR016040 NAD(P)-binding domain MB46_06155 45f0a6003dc615e30890be672663ddb7 260 Gene3D G3DSA:3.40.50.720 11 219 1.7E-43 T 14-10-2018 MB46_06155 45f0a6003dc615e30890be672663ddb7 260 SUPERFAMILY SSF51735 12 209 3.5E-33 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_11050 dc665914925f07be0b77eb0c2bd48a1b 218 Pfam PF13483 Beta-lactamase superfamily domain 3 173 2.2E-14 T 14-10-2018 MB46_11050 dc665914925f07be0b77eb0c2bd48a1b 218 SMART SM00849 7 175 0.0072 T 14-10-2018 IPR001279 Metallo-beta-lactamase MB46_11050 dc665914925f07be0b77eb0c2bd48a1b 218 SUPERFAMILY SSF56281 4 184 1.31E-17 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MB46_11050 dc665914925f07be0b77eb0c2bd48a1b 218 Gene3D G3DSA:3.60.15.10 1 192 3.2E-23 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MB46_07020 80f748c440ad02aae4edf8ced118e8a7 311 Gene3D G3DSA:1.10.10.10 1 86 1.4E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_07020 80f748c440ad02aae4edf8ced118e8a7 311 Pfam PF03466 LysR substrate binding domain 91 297 3.4E-38 T 14-10-2018 IPR005119 LysR, substrate-binding MB46_07020 80f748c440ad02aae4edf8ced118e8a7 311 Gene3D G3DSA:3.40.190.10 95 293 2.6E-51 T 14-10-2018 MB46_07020 80f748c440ad02aae4edf8ced118e8a7 311 SUPERFAMILY SSF53850 90 299 5.61E-40 T 14-10-2018 MB46_07020 80f748c440ad02aae4edf8ced118e8a7 311 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 66 1.2E-14 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MB46_07020 80f748c440ad02aae4edf8ced118e8a7 311 SUPERFAMILY SSF46785 4 115 2.35E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_07020 80f748c440ad02aae4edf8ced118e8a7 311 Gene3D G3DSA:3.40.190.10 165 271 2.6E-51 T 14-10-2018 MB46_01925 6f2c0ef2ddf39d38f3e95d53f53d82e2 155 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 11 128 1.9E-16 T 14-10-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MB46_01925 6f2c0ef2ddf39d38f3e95d53f53d82e2 155 Gene3D G3DSA:1.20.1300.10 22 137 4.4E-23 T 14-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MB46_01925 6f2c0ef2ddf39d38f3e95d53f53d82e2 155 SUPERFAMILY SSF81343 12 141 5.45E-35 T 14-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MB46_11680 442f35246273017f2602e25804be5463 372 Gene3D G3DSA:3.20.20.210 85 369 1.2E-18 T 14-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 MB46_11680 442f35246273017f2602e25804be5463 372 SUPERFAMILY SSF51726 94 366 4.45E-15 T 14-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 MB46_02895 6ef7e9f6f8f6be512ad740c14b34d7ba 199 Pfam PF03703 Bacterial PH domain 85 144 1.8E-10 T 14-10-2018 IPR005182 Domain of unknown function DUF304 MB46_18895 12cca3fa5f184039c9a66d117aeb9e6c 295 SUPERFAMILY SSF161098 57 283 9.81E-61 T 14-10-2018 IPR035906 MetI-like superfamily MB46_18895 12cca3fa5f184039c9a66d117aeb9e6c 295 Gene3D G3DSA:1.10.3720.10 53 294 2.4E-70 T 14-10-2018 IPR035906 MetI-like superfamily MB46_18895 12cca3fa5f184039c9a66d117aeb9e6c 295 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 95 292 1.9E-18 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_12075 c02c607707ced11bbe54b63dde8c3c48 327 Pfam PF00005 ABC transporter 21 169 2.7E-36 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_12075 c02c607707ced11bbe54b63dde8c3c48 327 Pfam PF09383 NIL domain 252 324 1.2E-17 T 14-10-2018 IPR018449 NIL domain MB46_12075 c02c607707ced11bbe54b63dde8c3c48 327 SUPERFAMILY SSF55021 247 326 2.86E-17 T 14-10-2018 MB46_12075 c02c607707ced11bbe54b63dde8c3c48 327 SMART SM00382 30 224 1.1E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_12075 c02c607707ced11bbe54b63dde8c3c48 327 SMART SM00930 250 325 1.2E-18 T 14-10-2018 IPR018449 NIL domain MB46_12075 c02c607707ced11bbe54b63dde8c3c48 327 Gene3D G3DSA:3.30.70.260 243 327 1.2E-20 T 14-10-2018 MB46_12075 c02c607707ced11bbe54b63dde8c3c48 327 Gene3D G3DSA:3.40.50.300 1 240 5.2E-78 T 14-10-2018 MB46_12075 c02c607707ced11bbe54b63dde8c3c48 327 SUPERFAMILY SSF52540 1 234 1.39E-80 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_12075 c02c607707ced11bbe54b63dde8c3c48 327 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_09140 4a3796e6379238a70e126ec7e6fcbd54 560 Gene3D G3DSA:3.40.50.300 285 558 2.0E-62 T 14-10-2018 MB46_09140 4a3796e6379238a70e126ec7e6fcbd54 560 Pfam PF12848 ABC transporter 229 298 2.8E-13 T 14-10-2018 IPR032781 ABC-transporter extension domain MB46_09140 4a3796e6379238a70e126ec7e6fcbd54 560 SMART SM00382 30 242 2.4E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_09140 4a3796e6379238a70e126ec7e6fcbd54 560 SMART SM00382 348 518 4.0E-7 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_09140 4a3796e6379238a70e126ec7e6fcbd54 560 ProSitePatterns PS00211 ABC transporters family signature. 162 176 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_09140 4a3796e6379238a70e126ec7e6fcbd54 560 Gene3D G3DSA:3.40.50.300 2 284 2.6E-77 T 14-10-2018 MB46_09140 4a3796e6379238a70e126ec7e6fcbd54 560 Pfam PF00005 ABC transporter 21 190 6.5E-27 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_09140 4a3796e6379238a70e126ec7e6fcbd54 560 SUPERFAMILY SSF52540 305 509 1.15E-42 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_09140 4a3796e6379238a70e126ec7e6fcbd54 560 SUPERFAMILY SSF52540 10 243 1.24E-48 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_09140 4a3796e6379238a70e126ec7e6fcbd54 560 ProSitePatterns PS00211 ABC transporters family signature. 445 459 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_09140 4a3796e6379238a70e126ec7e6fcbd54 560 Pfam PF00005 ABC transporter 340 473 8.3E-18 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_09140 4a3796e6379238a70e126ec7e6fcbd54 560 TIGRFAM TIGR03719 ABC_ABC_ChvD: ATP-binding cassette protein, ChvD family 3 557 3.9E-273 T 14-10-2018 IPR022374 Energy-dependent translational throttle protein EttA GO:0045900 MB46_05745 4a8da62144a4957c8c2c07c30fe4ab63 393 PIRSF PIRSF005962 1 392 5.6E-101 T 14-10-2018 IPR017439 Amidohydrolase GO:0016787 MB46_05745 4a8da62144a4957c8c2c07c30fe4ab63 393 Gene3D G3DSA:3.40.630.10 5 347 1.8E-117 T 14-10-2018 MB46_05745 4a8da62144a4957c8c2c07c30fe4ab63 393 Pfam PF07687 Peptidase dimerisation domain 174 269 1.8E-12 T 14-10-2018 IPR011650 Peptidase M20, dimerisation domain MB46_05745 4a8da62144a4957c8c2c07c30fe4ab63 393 SUPERFAMILY SSF53187 4 391 2.29E-74 T 14-10-2018 MB46_05745 4a8da62144a4957c8c2c07c30fe4ab63 393 Pfam PF01546 Peptidase family M20/M25/M40 60 342 8.4E-23 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 MB46_05745 4a8da62144a4957c8c2c07c30fe4ab63 393 SUPERFAMILY SSF55031 173 273 2.49E-26 T 14-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain MB46_05745 4a8da62144a4957c8c2c07c30fe4ab63 393 Gene3D G3DSA:3.30.70.360 170 285 1.8E-117 T 14-10-2018 MB46_05745 4a8da62144a4957c8c2c07c30fe4ab63 393 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 5 329 1.0E-84 T 14-10-2018 IPR017439 Amidohydrolase GO:0016787 MB46_02985 f55244214c988bc86155b26ed643891d 557 Gene3D G3DSA:3.90.400.10 120 192 1.0E-138 T 14-10-2018 MB46_02985 f55244214c988bc86155b26ed643891d 557 SMART SM00642 28 437 1.5E-113 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MB46_02985 f55244214c988bc86155b26ed643891d 557 SUPERFAMILY SSF51445 18 493 6.35E-115 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily MB46_02985 f55244214c988bc86155b26ed643891d 557 Gene3D G3DSA:3.20.20.80 20 491 1.0E-138 T 14-10-2018 MB46_02985 f55244214c988bc86155b26ed643891d 557 Pfam PF00128 Alpha amylase, catalytic domain 43 409 6.1E-76 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MB46_00180 c30d639845cbe7fc7c2fa299d1eb61e4 141 SUPERFAMILY SSF55729 15 122 4.82E-18 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase MB46_00180 c30d639845cbe7fc7c2fa299d1eb61e4 141 Pfam PF13673 Acetyltransferase (GNAT) domain 33 122 1.2E-11 T 14-10-2018 IPR000182 GNAT domain MB46_00180 c30d639845cbe7fc7c2fa299d1eb61e4 141 Gene3D G3DSA:3.40.630.30 6 129 3.9E-28 T 14-10-2018 MB46_02320 6b89b1d516cb8336176f4d0c0128ae99 296 Pfam PF00482 Type II secretion system (T2SS), protein F 156 281 4.4E-20 T 14-10-2018 IPR018076 Type II secretion system F domain MB46_02705 39434168c82d468991b9f3ecd8a463c3 239 SUPERFAMILY SSF52172 166 231 3.13E-5 T 14-10-2018 IPR011006 CheY-like superfamily MB46_02705 39434168c82d468991b9f3ecd8a463c3 239 SMART SM01012 176 231 4.5E-17 T 14-10-2018 IPR005561 ANTAR domain GO:0003723 MB46_02705 39434168c82d468991b9f3ecd8a463c3 239 SMART SM00065 26 174 2.7E-11 T 14-10-2018 IPR003018 GAF domain GO:0005515 MB46_02705 39434168c82d468991b9f3ecd8a463c3 239 Pfam PF13185 GAF domain 26 162 1.4E-16 T 14-10-2018 IPR003018 GAF domain GO:0005515 MB46_02705 39434168c82d468991b9f3ecd8a463c3 239 Gene3D G3DSA:3.30.450.40 3 175 1.1E-28 T 14-10-2018 IPR029016 GAF-like domain superfamily MB46_02705 39434168c82d468991b9f3ecd8a463c3 239 Gene3D G3DSA:1.10.10.10 178 236 2.2E-8 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_02705 39434168c82d468991b9f3ecd8a463c3 239 PIRSF PIRSF036625 4 239 1.1E-56 T 14-10-2018 IPR012074 GAF-ANTAR transcription anti-termination regulator, putative MB46_02705 39434168c82d468991b9f3ecd8a463c3 239 Pfam PF03861 ANTAR domain 178 231 4.1E-14 T 14-10-2018 IPR005561 ANTAR domain GO:0003723 MB46_02705 39434168c82d468991b9f3ecd8a463c3 239 SUPERFAMILY SSF55781 29 172 1.61E-24 T 14-10-2018 MB46_12110 81cfca75792565e30cc021fdf785af2c 266 SUPERFAMILY SSF110399 9 251 2.09E-77 T 14-10-2018 MB46_12110 81cfca75792565e30cc021fdf785af2c 266 Pfam PF05690 Thiazole biosynthesis protein ThiG 13 258 7.7E-98 T 14-10-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 MB46_12110 81cfca75792565e30cc021fdf785af2c 266 Hamap MF_00443 Thiazole synthase [thiG]. 10 265 39.513 T 14-10-2018 IPR008867 Thiazole synthase GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 MB46_12110 81cfca75792565e30cc021fdf785af2c 266 Gene3D G3DSA:3.20.20.70 1 264 3.3E-102 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MB46_03115 a7326f7c45ca83d3e3d4a905bbce2023 214 PIRSF PIRSF006324 1 212 3.1E-41 T 14-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 MB46_03115 a7326f7c45ca83d3e3d4a905bbce2023 214 Pfam PF01810 LysE type translocator 15 210 7.3E-27 T 14-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 MB46_15215 cd944a7ec7363e93a77d0c3ce92c98dc 103 Pfam PF05437 Branched-chain amino acid transport protein (AzlD) 3 98 1.0E-7 T 14-10-2018 IPR008407 Branched-chain amino acid transport, AzlD MB46_05250 a8d42161b5d4f3253dfb8aeba9b21bd6 84 SUPERFAMILY SSF143800 2 81 5.1E-22 T 14-10-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_05250 a8d42161b5d4f3253dfb8aeba9b21bd6 84 Hamap MF_00502 50S ribosomal protein L31 type B [rpmE2]. 1 81 25.43 T 14-10-2018 IPR027493 Ribosomal protein L31 type B GO:0003735|GO:0005622|GO:0005840|GO:0006412 MB46_05250 a8d42161b5d4f3253dfb8aeba9b21bd6 84 Gene3D G3DSA:2.30.170.50 1 84 9.2E-27 T 14-10-2018 MB46_05250 a8d42161b5d4f3253dfb8aeba9b21bd6 84 Pfam PF01197 Ribosomal protein L31 2 79 1.0E-28 T 14-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MB46_05250 a8d42161b5d4f3253dfb8aeba9b21bd6 84 PRINTS PR01249 Ribosomal protein L31 signature 45 60 8.6E-19 T 14-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MB46_05250 a8d42161b5d4f3253dfb8aeba9b21bd6 84 PRINTS PR01249 Ribosomal protein L31 signature 60 78 8.6E-19 T 14-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MB46_05250 a8d42161b5d4f3253dfb8aeba9b21bd6 84 PRINTS PR01249 Ribosomal protein L31 signature 2 19 8.6E-19 T 14-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MB46_05250 a8d42161b5d4f3253dfb8aeba9b21bd6 84 ProSitePatterns PS01143 Ribosomal protein L31 signature. 49 70 - T 14-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MB46_05250 a8d42161b5d4f3253dfb8aeba9b21bd6 84 TIGRFAM TIGR00105 L31: ribosomal protein bL31 2 80 1.6E-21 T 14-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MB46_06150 92d325de31608f177442edd80b499464 338 SUPERFAMILY SSF51430 1 315 1.57E-101 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily MB46_06150 92d325de31608f177442edd80b499464 338 Pfam PF00248 Aldo/keto reductase family 15 313 3.2E-77 T 14-10-2018 IPR023210 NADP-dependent oxidoreductase domain MB46_06150 92d325de31608f177442edd80b499464 338 Gene3D G3DSA:3.20.20.100 1 326 7.7E-119 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily MB46_06150 92d325de31608f177442edd80b499464 338 PRINTS PR00069 Aldo-keto reductase signature 105 123 9.3E-9 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MB46_06150 92d325de31608f177442edd80b499464 338 PRINTS PR00069 Aldo-keto reductase signature 136 153 9.3E-9 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MB46_06150 92d325de31608f177442edd80b499464 338 PRINTS PR00069 Aldo-keto reductase signature 41 65 9.3E-9 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MB46_18845 e17e075706516217f6963ba0ac340626 445 SMART SM00922 199 295 5.7E-27 T 14-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal MB46_18845 e17e075706516217f6963ba0ac340626 445 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 245 276 - T 14-10-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 MB46_18845 e17e075706516217f6963ba0ac340626 445 Gene3D G3DSA:3.30.390.10 1 131 8.8E-53 T 14-10-2018 IPR029017 Enolase-like, N-terminal MB46_18845 e17e075706516217f6963ba0ac340626 445 Gene3D G3DSA:3.20.20.120 132 434 4.3E-109 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily MB46_18845 e17e075706516217f6963ba0ac340626 445 SUPERFAMILY SSF54826 3 139 7.41E-40 T 14-10-2018 MB46_18845 e17e075706516217f6963ba0ac340626 445 Pfam PF13378 Enolase C-terminal domain-like 203 415 4.7E-61 T 14-10-2018 IPR029065 Enolase C-terminal domain-like MB46_18845 e17e075706516217f6963ba0ac340626 445 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 42 136 7.0E-9 T 14-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain MB46_18845 e17e075706516217f6963ba0ac340626 445 SUPERFAMILY SSF51604 184 430 5.11E-68 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily MB46_14845 94e6f5f9aea3595224bd618cc1d14a7d 385 Pfam PF02595 Glycerate kinase family 3 370 4.0E-125 T 14-10-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 MB46_14845 94e6f5f9aea3595224bd618cc1d14a7d 385 SUPERFAMILY SSF110738 1 369 2.22E-115 T 14-10-2018 IPR036129 Glycerate kinase superfamily GO:0008887|GO:0031388 MB46_14845 94e6f5f9aea3595224bd618cc1d14a7d 385 PIRSF PIRSF006078 1 378 2.3E-122 T 14-10-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 MB46_14845 94e6f5f9aea3595224bd618cc1d14a7d 385 TIGRFAM TIGR00045 TIGR00045: glycerate kinase 2 369 3.6E-116 T 14-10-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 MB46_14845 94e6f5f9aea3595224bd618cc1d14a7d 385 Gene3D G3DSA:3.40.50.10350 1 362 4.1E-123 T 14-10-2018 IPR018197 Glycerate kinase, restriction-enzyme-like fold MB46_14845 94e6f5f9aea3595224bd618cc1d14a7d 385 Gene3D G3DSA:3.90.1510.10 42 276 4.1E-123 T 14-10-2018 IPR018193 Glycerate kinase, flavodoxin-like fold GO:0008887|GO:0031388 MB46_05585 524832aea6803a6ec67f62f1131bb94a 184 SUPERFAMILY SSF52499 4 142 2.88E-42 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 MB46_05585 524832aea6803a6ec67f62f1131bb94a 184 Gene3D G3DSA:3.40.50.850 7 166 2.4E-42 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 MB46_05585 524832aea6803a6ec67f62f1131bb94a 184 Pfam PF00857 Isochorismatase family 10 145 2.5E-36 T 14-10-2018 IPR000868 Isochorismatase-like GO:0003824 MB46_18700 155dd9a787ed124d119a8d02073ef5c0 393 Pfam PF06224 Winged helix DNA-binding domain 41 338 3.6E-25 T 14-10-2018 IPR009351 Protein of unknown function DUF1006 MB46_16610 9a80cf6ca29b141a3d211e4022a962fb 341 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 138 236 2.8E-10 T 14-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 MB46_16610 9a80cf6ca29b141a3d211e4022a962fb 341 SUPERFAMILY SSF55347 133 289 1.8E-23 T 14-10-2018 MB46_16610 9a80cf6ca29b141a3d211e4022a962fb 341 Gene3D G3DSA:3.30.360.10 130 334 1.3E-104 T 14-10-2018 MB46_16610 9a80cf6ca29b141a3d211e4022a962fb 341 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 5 123 3.2E-17 T 14-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 MB46_16610 9a80cf6ca29b141a3d211e4022a962fb 341 Gene3D G3DSA:3.40.50.720 5 320 1.3E-104 T 14-10-2018 MB46_16610 9a80cf6ca29b141a3d211e4022a962fb 341 SUPERFAMILY SSF51735 3 158 6.12E-35 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_15050 3d8fa1c57ceaf296a678232d3ea16ee2 296 Gene3D G3DSA:1.10.3720.10 16 284 1.0E-64 T 14-10-2018 IPR035906 MetI-like superfamily MB46_15050 3d8fa1c57ceaf296a678232d3ea16ee2 296 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 105 289 7.1E-22 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_15050 3d8fa1c57ceaf296a678232d3ea16ee2 296 SUPERFAMILY SSF161098 22 296 9.35E-73 T 14-10-2018 IPR035906 MetI-like superfamily MB46_09975 9dc33c0eb07907d115a8b93c5a2d0ce2 248 Gene3D G3DSA:1.20.120.1600 31 117 3.6E-35 T 14-10-2018 MB46_09975 9dc33c0eb07907d115a8b93c5a2d0ce2 248 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 180 200 2.8E-8 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MB46_09975 9dc33c0eb07907d115a8b93c5a2d0ce2 248 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 132 145 2.8E-8 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MB46_09975 9dc33c0eb07907d115a8b93c5a2d0ce2 248 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 17 28 2.8E-8 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MB46_09975 9dc33c0eb07907d115a8b93c5a2d0ce2 248 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 162 178 2.8E-8 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MB46_09975 9dc33c0eb07907d115a8b93c5a2d0ce2 248 Gene3D G3DSA:3.40.50.1000 20 226 3.6E-35 T 14-10-2018 IPR023214 HAD superfamily MB46_09975 9dc33c0eb07907d115a8b93c5a2d0ce2 248 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 102 213 2.6E-10 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MB46_09975 9dc33c0eb07907d115a8b93c5a2d0ce2 248 Pfam PF13419 Haloacid dehalogenase-like hydrolase 20 218 2.1E-17 T 14-10-2018 MB46_09975 9dc33c0eb07907d115a8b93c5a2d0ce2 248 SUPERFAMILY SSF56784 17 246 7.97E-37 T 14-10-2018 IPR036412 HAD-like superfamily MB46_07965 cdcbaabeb9b0023e69993e1c364d9068 172 Gene3D G3DSA:1.20.120.450 36 172 1.4E-16 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes MB46_07965 cdcbaabeb9b0023e69993e1c364d9068 172 SUPERFAMILY SSF109854 17 170 2.29E-19 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes MB46_04190 064caa5d4717ca3b2ed63268888980de 222 Hamap MF_00527 Putative 3-methyladenine DNA glycosylase. 9 201 30.199 T 14-10-2018 IPR003180 Methylpurine-DNA glycosylase GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 MB46_04190 064caa5d4717ca3b2ed63268888980de 222 TIGRFAM TIGR00567 3mg: DNA-3-methyladenine glycosylase 9 201 4.1E-50 T 14-10-2018 IPR003180 Methylpurine-DNA glycosylase GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 MB46_04190 064caa5d4717ca3b2ed63268888980de 222 Gene3D G3DSA:3.10.300.10 6 208 8.9E-59 T 14-10-2018 IPR036995 Methylpurine-DNA glycosylase superfamily GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 MB46_04190 064caa5d4717ca3b2ed63268888980de 222 Pfam PF02245 Methylpurine-DNA glycosylase (MPG) 12 198 7.1E-58 T 14-10-2018 IPR003180 Methylpurine-DNA glycosylase GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 MB46_04190 064caa5d4717ca3b2ed63268888980de 222 SUPERFAMILY SSF50486 8 207 5.49E-55 T 14-10-2018 IPR011034 Formyl transferase-like, C-terminal domain superfamily GO:0003824 MB46_04315 738d35dd17a0d3e6a8340b92b4d8f296 211 Pfam PF01081 KDPG and KHG aldolase 9 200 1.6E-46 T 14-10-2018 IPR000887 KDPG/KHG aldolase GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 MB46_04315 738d35dd17a0d3e6a8340b92b4d8f296 211 SUPERFAMILY SSF51569 3 209 2.56E-57 T 14-10-2018 MB46_04315 738d35dd17a0d3e6a8340b92b4d8f296 211 TIGRFAM TIGR01182 eda: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 9 205 2.3E-57 T 14-10-2018 IPR000887 KDPG/KHG aldolase GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 MB46_04315 738d35dd17a0d3e6a8340b92b4d8f296 211 Gene3D G3DSA:3.20.20.70 1 211 8.1E-67 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MB46_01035 187239f888b9afe78ecafb5d36907cd3 270 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 71 84 - T 14-10-2018 IPR018313 Solute-binding protein family 3, conserved site MB46_01035 187239f888b9afe78ecafb5d36907cd3 270 Gene3D G3DSA:3.40.190.10 46 258 4.4E-66 T 14-10-2018 MB46_01035 187239f888b9afe78ecafb5d36907cd3 270 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 48 266 3.9E-57 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MB46_01035 187239f888b9afe78ecafb5d36907cd3 270 Gene3D G3DSA:3.40.190.10 131 228 4.4E-66 T 14-10-2018 MB46_01035 187239f888b9afe78ecafb5d36907cd3 270 SMART SM00062 47 267 4.9E-70 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MB46_01035 187239f888b9afe78ecafb5d36907cd3 270 SUPERFAMILY SSF53850 6 267 1.02E-59 T 14-10-2018 MB46_09505 8de37d2d41492510af99a28ecd9e786d 431 Gene3D G3DSA:3.40.50.450 23 354 2.4E-85 T 14-10-2018 MB46_09505 8de37d2d41492510af99a28ecd9e786d 431 Pfam PF02481 DNA recombination-mediator protein A 107 341 5.7E-66 T 14-10-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 MB46_09505 8de37d2d41492510af99a28ecd9e786d 431 SUPERFAMILY SSF102405 132 350 3.14E-30 T 14-10-2018 MB46_04295 7b479a803dbf72a2996a600a94cd7d62 253 Gene3D G3DSA:3.30.450.40 71 252 1.7E-53 T 14-10-2018 IPR029016 GAF-like domain superfamily MB46_04295 7b479a803dbf72a2996a600a94cd7d62 253 Gene3D G3DSA:1.10.10.10 2 70 2.7E-16 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_04295 7b479a803dbf72a2996a600a94cd7d62 253 SUPERFAMILY SSF46785 3 73 2.69E-13 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_04295 7b479a803dbf72a2996a600a94cd7d62 253 Pfam PF01614 Bacterial transcriptional regulator 117 241 2.1E-30 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal MB46_04295 7b479a803dbf72a2996a600a94cd7d62 253 SMART SM00346 2 89 6.2E-23 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 MB46_04295 7b479a803dbf72a2996a600a94cd7d62 253 SUPERFAMILY SSF55781 64 246 1.52E-48 T 14-10-2018 MB46_04295 7b479a803dbf72a2996a600a94cd7d62 253 Pfam PF09339 IclR helix-turn-helix domain 4 52 8.4E-8 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 MB46_04450 eddcad5a0a51b4a8a57497e72e851ff3 215 SUPERFAMILY SSF46785 115 187 9.14E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_04450 eddcad5a0a51b4a8a57497e72e851ff3 215 SUPERFAMILY SSF46785 26 110 8.71E-14 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_04450 eddcad5a0a51b4a8a57497e72e851ff3 215 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 29 198 5.9E-28 T 14-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 MB46_04450 eddcad5a0a51b4a8a57497e72e851ff3 215 Gene3D G3DSA:1.10.10.10 17 113 3.3E-28 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_04450 eddcad5a0a51b4a8a57497e72e851ff3 215 Gene3D G3DSA:1.10.10.10 114 207 9.6E-32 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_04450 eddcad5a0a51b4a8a57497e72e851ff3 215 Pfam PF04079 Segregation and condensation complex subunit ScpB 31 197 5.7E-54 T 14-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 MB46_04450 eddcad5a0a51b4a8a57497e72e851ff3 215 PIRSF PIRSF019345 12 214 4.8E-47 T 14-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 MB46_03960 9e153451bcefa37b7475506f1ae42d2d 106 Gene3D G3DSA:3.10.350.10 52 103 8.1E-11 T 14-10-2018 IPR036779 LysM domain superfamily MB46_03960 9e153451bcefa37b7475506f1ae42d2d 106 SMART SM00257 54 103 1.5E-6 T 14-10-2018 IPR018392 LysM domain MB46_03960 9e153451bcefa37b7475506f1ae42d2d 106 SUPERFAMILY SSF54106 56 104 2.22E-5 T 14-10-2018 MB46_03960 9e153451bcefa37b7475506f1ae42d2d 106 Pfam PF01476 LysM domain 56 103 9.0E-7 T 14-10-2018 IPR018392 LysM domain MB46_05635 fda8947bd22f64065f6915eae7e8b677 269 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 1 261 8.0E-26 T 14-10-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase MB46_01185 999f038b10d5e7abede98332a1d725b1 282 Pfam PF13460 NAD(P)H-binding 10 183 1.8E-25 T 14-10-2018 IPR016040 NAD(P)-binding domain MB46_01185 999f038b10d5e7abede98332a1d725b1 282 Gene3D G3DSA:3.90.25.10 138 267 7.5E-76 T 14-10-2018 MB46_01185 999f038b10d5e7abede98332a1d725b1 282 Gene3D G3DSA:3.40.50.720 7 266 7.5E-76 T 14-10-2018 MB46_01185 999f038b10d5e7abede98332a1d725b1 282 SUPERFAMILY SSF51735 3 250 6.46E-53 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_08620 bebb4d35e5e3f97832b706d18beb28fa 593 Hamap MF_00044 Aspartate--tRNA(Asp/Asn) ligase [aspS]. 2 583 31.753 T 14-10-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 MB46_08620 bebb4d35e5e3f97832b706d18beb28fa 593 Pfam PF02938 GAD domain 309 389 7.8E-16 T 14-10-2018 IPR029351 GAD domain Reactome: R-HSA-379726 MB46_08620 bebb4d35e5e3f97832b706d18beb28fa 593 Gene3D G3DSA:2.40.50.140 1 102 1.4E-31 T 14-10-2018 MB46_08620 bebb4d35e5e3f97832b706d18beb28fa 593 Gene3D G3DSA:3.30.930.10 114 579 3.8E-177 T 14-10-2018 MB46_08620 bebb4d35e5e3f97832b706d18beb28fa 593 Gene3D G3DSA:3.30.1360.30 269 408 3.8E-177 T 14-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 MB46_08620 bebb4d35e5e3f97832b706d18beb28fa 593 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 3 579 5.0E-205 T 14-10-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 MB46_08620 bebb4d35e5e3f97832b706d18beb28fa 593 PRINTS PR01042 Aspartyl-tRNA synthetase signature 188 200 5.7E-25 T 14-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 MB46_08620 bebb4d35e5e3f97832b706d18beb28fa 593 PRINTS PR01042 Aspartyl-tRNA synthetase signature 517 531 5.7E-25 T 14-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 MB46_08620 bebb4d35e5e3f97832b706d18beb28fa 593 PRINTS PR01042 Aspartyl-tRNA synthetase signature 473 489 5.7E-25 T 14-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 MB46_08620 bebb4d35e5e3f97832b706d18beb28fa 593 PRINTS PR01042 Aspartyl-tRNA synthetase signature 205 218 5.7E-25 T 14-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 MB46_08620 bebb4d35e5e3f97832b706d18beb28fa 593 SUPERFAMILY SSF55681 109 582 3.32E-95 T 14-10-2018 MB46_08620 bebb4d35e5e3f97832b706d18beb28fa 593 Pfam PF00152 tRNA synthetases class II (D, K and N) 116 556 9.0E-97 T 14-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 MB46_08620 bebb4d35e5e3f97832b706d18beb28fa 593 SUPERFAMILY SSF50249 2 101 9.33E-29 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold MB46_08620 bebb4d35e5e3f97832b706d18beb28fa 593 Pfam PF01336 OB-fold nucleic acid binding domain 19 98 5.2E-14 T 14-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 MB46_08620 bebb4d35e5e3f97832b706d18beb28fa 593 SUPERFAMILY SSF55261 286 408 8.99E-36 T 14-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 MB46_15040 84f69db1afc7429cfa4fe76eec52642f 344 Gene3D G3DSA:3.40.50.2300 167 299 7.2E-70 T 14-10-2018 MB46_15040 84f69db1afc7429cfa4fe76eec52642f 344 ProSitePatterns PS00356 LacI-type HTH domain signature. 12 30 - T 14-10-2018 MB46_15040 84f69db1afc7429cfa4fe76eec52642f 344 Pfam PF13377 Periplasmic binding protein-like domain 175 339 5.4E-36 T 14-10-2018 MB46_15040 84f69db1afc7429cfa4fe76eec52642f 344 Gene3D G3DSA:1.10.260.40 3 63 2.3E-22 T 14-10-2018 MB46_15040 84f69db1afc7429cfa4fe76eec52642f 344 Pfam PF00356 Bacterial regulatory proteins, lacI family 11 56 2.3E-16 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MB46_15040 84f69db1afc7429cfa4fe76eec52642f 344 SMART SM00354 9 79 1.5E-26 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MB46_15040 84f69db1afc7429cfa4fe76eec52642f 344 SUPERFAMILY SSF53822 68 340 8.64E-63 T 14-10-2018 IPR028082 Periplasmic binding protein-like I MB46_15040 84f69db1afc7429cfa4fe76eec52642f 344 Gene3D G3DSA:3.40.50.2300 64 315 7.2E-70 T 14-10-2018 MB46_15040 84f69db1afc7429cfa4fe76eec52642f 344 SUPERFAMILY SSF47413 8 67 4.88E-17 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MB46_09020 0ffda8b1decf87d931d24a2274fbbd7e 873 PRINTS PR00986 Valyl-tRNA synthetase signature 53 64 1.1E-19 T 14-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 MB46_09020 0ffda8b1decf87d931d24a2274fbbd7e 873 PRINTS PR00986 Valyl-tRNA synthetase signature 546 564 1.1E-19 T 14-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 MB46_09020 0ffda8b1decf87d931d24a2274fbbd7e 873 PRINTS PR00986 Valyl-tRNA synthetase signature 266 283 1.1E-19 T 14-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 MB46_09020 0ffda8b1decf87d931d24a2274fbbd7e 873 PRINTS PR00986 Valyl-tRNA synthetase signature 395 408 1.1E-19 T 14-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 MB46_09020 0ffda8b1decf87d931d24a2274fbbd7e 873 PRINTS PR00986 Valyl-tRNA synthetase signature 515 536 1.1E-19 T 14-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 MB46_09020 0ffda8b1decf87d931d24a2274fbbd7e 873 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 32 631 3.3E-94 T 14-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 MB46_09020 0ffda8b1decf87d931d24a2274fbbd7e 873 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 60 71 - T 14-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 MB46_09020 0ffda8b1decf87d931d24a2274fbbd7e 873 Gene3D G3DSA:3.40.50.620 38 595 2.9E-189 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MB46_09020 0ffda8b1decf87d931d24a2274fbbd7e 873 SUPERFAMILY SSF50677 228 381 1.14E-30 T 14-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 MB46_09020 0ffda8b1decf87d931d24a2274fbbd7e 873 Pfam PF08264 Anticodon-binding domain of tRNA 677 816 1.6E-28 T 14-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 MB46_09020 0ffda8b1decf87d931d24a2274fbbd7e 873 Hamap MF_02005 Valine--tRNA ligase [valS]. 18 850 26.874 T 14-10-2018 IPR022874 Valine-tRNA ligase, type 2 GO:0004832 KEGG: 00970+6.1.1.9 MB46_09020 0ffda8b1decf87d931d24a2274fbbd7e 873 Gene3D G3DSA:1.10.730.10 27 806 2.9E-189 T 14-10-2018 MB46_09020 0ffda8b1decf87d931d24a2274fbbd7e 873 SUPERFAMILY SSF47323 646 856 3.74E-37 T 14-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 MB46_09020 0ffda8b1decf87d931d24a2274fbbd7e 873 Gene3D G3DSA:3.90.740.10 212 391 2.9E-189 T 14-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 MB46_09020 0ffda8b1decf87d931d24a2274fbbd7e 873 SUPERFAMILY SSF52374 25 635 2.09E-103 T 14-10-2018 MB46_19045 eb1006480a732a95c92b634888d6df07 220 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 4 211 7.9E-46 T 14-10-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 MB46_19045 eb1006480a732a95c92b634888d6df07 220 Gene3D G3DSA:1.20.58.220 1 213 1.1E-48 T 14-10-2018 IPR038078 PhoU-like domain superfamily MB46_19045 eb1006480a732a95c92b634888d6df07 220 Pfam PF01895 PhoU domain 17 103 8.7E-17 T 14-10-2018 IPR026022 PhoU domain MB46_19045 eb1006480a732a95c92b634888d6df07 220 Pfam PF01895 PhoU domain 134 203 8.3E-6 T 14-10-2018 IPR026022 PhoU domain MB46_19045 eb1006480a732a95c92b634888d6df07 220 SUPERFAMILY SSF109755 2 214 3.03E-48 T 14-10-2018 MB46_19045 eb1006480a732a95c92b634888d6df07 220 PIRSF PIRSF003107 1 216 8.5E-45 T 14-10-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 MB46_00560 f1bc58814a887efbd2d122183ba0f5f5 237 SUPERFAMILY SSF51735 1 205 3.36E-45 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_00560 f1bc58814a887efbd2d122183ba0f5f5 237 Gene3D G3DSA:3.40.50.720 1 227 1.3E-46 T 14-10-2018 MB46_00560 f1bc58814a887efbd2d122183ba0f5f5 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 142 161 2.2E-15 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_00560 f1bc58814a887efbd2d122183ba0f5f5 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 70 81 2.2E-15 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_00560 f1bc58814a887efbd2d122183ba0f5f5 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 180 2.2E-15 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_00560 f1bc58814a887efbd2d122183ba0f5f5 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 2.2E-15 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_00560 f1bc58814a887efbd2d122183ba0f5f5 237 Pfam PF00106 short chain dehydrogenase 8 186 2.2E-33 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_00560 f1bc58814a887efbd2d122183ba0f5f5 237 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 70 81 9.1E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_00560 f1bc58814a887efbd2d122183ba0f5f5 237 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 142 161 9.1E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_00560 f1bc58814a887efbd2d122183ba0f5f5 237 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 124 132 9.1E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_11770 6037052b1ba91361a2a18192d97d3b26 157 Pfam PF00588 SpoU rRNA Methylase family 3 141 7.7E-30 T 14-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 MB46_11770 6037052b1ba91361a2a18192d97d3b26 157 Hamap MF_01885 tRNA (cytidine(34)-2'-O)-methyltransferase [trmL]. 2 151 30.93 T 14-10-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 MB46_11770 6037052b1ba91361a2a18192d97d3b26 157 SUPERFAMILY SSF75217 3 152 3.53E-40 T 14-10-2018 IPR029028 Alpha/beta knot methyltransferases MB46_11770 6037052b1ba91361a2a18192d97d3b26 157 Gene3D G3DSA:3.40.1280.10 1 157 3.7E-56 T 14-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal MB46_11770 6037052b1ba91361a2a18192d97d3b26 157 PIRSF PIRSF029256 1 154 9.7E-57 T 14-10-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 MB46_09730 61a15818826807d7c7e5a9d15468a9f9 1209 SMART SM00968 510 636 6.8E-17 T 14-10-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 MB46_09730 61a15818826807d7c7e5a9d15468a9f9 1209 SUPERFAMILY SSF52540 2 1195 1.7E-67 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_09730 61a15818826807d7c7e5a9d15468a9f9 1209 Gene3D G3DSA:3.40.50.300 964 1209 1.3E-43 T 14-10-2018 MB46_09730 61a15818826807d7c7e5a9d15468a9f9 1209 Gene3D G3DSA:3.40.50.300 1 268 5.1E-53 T 14-10-2018 MB46_09730 61a15818826807d7c7e5a9d15468a9f9 1209 Hamap MF_01894 Chromosome partition protein Smc [smc]. 1 1204 21.832 T 14-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 MB46_09730 61a15818826807d7c7e5a9d15468a9f9 1209 PIRSF PIRSF005719 1 1209 4.7E-234 T 14-10-2018 IPR024704 Structural maintenance of chromosomes protein MB46_09730 61a15818826807d7c7e5a9d15468a9f9 1209 SUPERFAMILY SSF75553 465 678 1.7E-19 T 14-10-2018 IPR036277 SMCs flexible hinge superfamily GO:0005515|GO:0005524|GO:0005694|GO:0051276 MB46_09730 61a15818826807d7c7e5a9d15468a9f9 1209 TIGRFAM TIGR02168 SMC_prok_B: chromosome segregation protein SMC 3 1202 4.0E-263 T 14-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 MB46_09730 61a15818826807d7c7e5a9d15468a9f9 1209 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 1195 1.7E-69 T 14-10-2018 IPR003395 RecF/RecN/SMC, N-terminal MB46_09730 61a15818826807d7c7e5a9d15468a9f9 1209 Gene3D G3DSA:1.20.1060.20 476 580 1.4E-6 T 14-10-2018 MB46_09730 61a15818826807d7c7e5a9d15468a9f9 1209 Pfam PF06470 SMC proteins Flexible Hinge Domain 511 635 1.0E-15 T 14-10-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 MB46_13720 343d2915f860b5215c04ea2c5c080352 361 Gene3D G3DSA:3.30.43.10 1 71 4.7E-19 T 14-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 MB46_13720 343d2915f860b5215c04ea2c5c080352 361 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 219 357 1.4E-34 T 14-10-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MB46_13720 343d2915f860b5215c04ea2c5c080352 361 Pfam PF01565 FAD binding domain 23 147 1.5E-20 T 14-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 MB46_13720 343d2915f860b5215c04ea2c5c080352 361 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 9 353 2.6E-46 T 14-10-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MB46_13720 343d2915f860b5215c04ea2c5c080352 361 Gene3D G3DSA:3.90.78.10 236 360 2.6E-33 T 14-10-2018 IPR036635 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain superfamily GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MB46_13720 343d2915f860b5215c04ea2c5c080352 361 Gene3D G3DSA:3.30.465.10 75 230 5.1E-39 T 14-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 MB46_13720 343d2915f860b5215c04ea2c5c080352 361 SUPERFAMILY SSF56176 7 189 2.2E-33 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 MB46_13720 343d2915f860b5215c04ea2c5c080352 361 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 361 73.341 T 14-10-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MB46_13720 343d2915f860b5215c04ea2c5c080352 361 SUPERFAMILY SSF56194 218 359 1.44E-28 T 14-10-2018 IPR036635 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain superfamily GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MB46_14260 e01418aa453d544e562d2c60f4dfd40c 231 SUPERFAMILY SSF53800 7 223 4.58E-22 T 14-10-2018 MB46_14260 e01418aa453d544e562d2c60f4dfd40c 231 Pfam PF01903 CbiX 12 109 1.2E-13 T 14-10-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 MB46_14260 e01418aa453d544e562d2c60f4dfd40c 231 Pfam PF01903 CbiX 126 192 3.3E-7 T 14-10-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 MB46_14260 e01418aa453d544e562d2c60f4dfd40c 231 Gene3D G3DSA:3.40.50.1400 118 227 1.3E-13 T 14-10-2018 MB46_14260 e01418aa453d544e562d2c60f4dfd40c 231 Gene3D G3DSA:3.40.50.1400 4 117 2.0E-22 T 14-10-2018 MB46_06250 b4790410315196690eb87ce9c87a427a 349 Gene3D G3DSA:3.40.50.720 12 115 1.3E-11 T 14-10-2018 MB46_06250 b4790410315196690eb87ce9c87a427a 349 SUPERFAMILY SSF51735 13 136 7.64E-9 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_11515 3bec04f35d6f25e8fab67216b17eec91 363 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 13 355 1.7E-116 T 14-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase MB46_11515 3bec04f35d6f25e8fab67216b17eec91 363 Gene3D G3DSA:3.90.1150.10 246 361 1.1E-29 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MB46_11515 3bec04f35d6f25e8fab67216b17eec91 363 PIRSF PIRSF000390 1 363 6.1E-101 T 14-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase MB46_11515 3bec04f35d6f25e8fab67216b17eec91 363 Gene3D G3DSA:3.40.640.10 1 243 4.2E-87 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MB46_11515 3bec04f35d6f25e8fab67216b17eec91 363 SUPERFAMILY SSF53383 5 360 2.11E-100 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MB46_01830 6c677e7e3c4a9cdb3e5324314d0d5f66 252 SUPERFAMILY SSF88713 4 251 2.08E-95 T 14-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 MB46_01830 6c677e7e3c4a9cdb3e5324314d0d5f66 252 Pfam PF03746 LamB/YcsF family 4 241 2.0E-99 T 14-10-2018 IPR005501 UPF0271 family, LamB/YcsF/PxpA KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 MB46_01830 6c677e7e3c4a9cdb3e5324314d0d5f66 252 Gene3D G3DSA:3.20.20.370 3 251 1.8E-100 T 14-10-2018 MB46_01830 6c677e7e3c4a9cdb3e5324314d0d5f66 252 Hamap MF_00691 UPF0271 protein YbgL [ybgL]. 2 246 42.809 T 14-10-2018 IPR005501 UPF0271 family, LamB/YcsF/PxpA KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 MB46_15815 ff0f278a7e9089bbe9a161694082d42d 490 Pfam PF15609 Phosphoribosyl transferase 35 270 1.6E-61 T 14-10-2018 MB46_15815 ff0f278a7e9089bbe9a161694082d42d 490 SUPERFAMILY SSF53271 116 243 1.07E-8 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like MB46_15815 ff0f278a7e9089bbe9a161694082d42d 490 Gene3D G3DSA:3.40.50.2020 104 267 1.1E-7 T 14-10-2018 MB46_15815 ff0f278a7e9089bbe9a161694082d42d 490 Pfam PF12500 TRSP domain C terminus to PRTase_2 319 440 6.7E-23 T 14-10-2018 IPR022537 TRSP domain MB46_15815 ff0f278a7e9089bbe9a161694082d42d 490 PIRSF PIRSF020967 10 78 5.8E-10 T 14-10-2018 IPR011214 Uncharacterised conserved protein UCP020967 MB46_15815 ff0f278a7e9089bbe9a161694082d42d 490 PIRSF PIRSF020967 116 449 5.2E-20 T 14-10-2018 IPR011214 Uncharacterised conserved protein UCP020967 MB46_13305 c497fccdc62a26de1169bcb3f4d428b3 322 Pfam PF03576 Peptidase family S58 11 307 5.2E-62 T 14-10-2018 IPR005321 Peptidase S58, DmpA MB46_13305 c497fccdc62a26de1169bcb3f4d428b3 322 Gene3D G3DSA:3.60.70.12 7 320 1.6E-109 T 14-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 MB46_13305 c497fccdc62a26de1169bcb3f4d428b3 322 SUPERFAMILY SSF56266 10 305 2.46E-66 T 14-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 MB46_10065 3207436342f16da9228ca679a6332768 284 Pfam PF01040 UbiA prenyltransferase family 18 263 9.0E-32 T 14-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 MB46_04390 598fbdb04e1aae0d80efb415e5dec6d4 427 SUPERFAMILY SSF118215 9 395 1.83E-70 T 14-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 MB46_04390 598fbdb04e1aae0d80efb415e5dec6d4 427 Gene3D G3DSA:1.10.3860.10 1 399 2.2E-50 T 14-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 MB46_04390 598fbdb04e1aae0d80efb415e5dec6d4 427 Pfam PF00375 Sodium:dicarboxylate symporter family 9 394 2.4E-68 T 14-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 MB46_05090 bb10c5f752ae2dde714c5dbe719f73e0 514 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 216 512 2.5E-109 T 14-10-2018 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MB46_05090 bb10c5f752ae2dde714c5dbe719f73e0 514 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 353 379 9.3E-48 T 14-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MB46_05090 bb10c5f752ae2dde714c5dbe719f73e0 514 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 246 263 9.3E-48 T 14-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MB46_05090 bb10c5f752ae2dde714c5dbe719f73e0 514 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 170 183 9.3E-48 T 14-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MB46_05090 bb10c5f752ae2dde714c5dbe719f73e0 514 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 264 280 9.3E-48 T 14-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MB46_05090 bb10c5f752ae2dde714c5dbe719f73e0 514 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 194 222 9.3E-48 T 14-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MB46_05090 bb10c5f752ae2dde714c5dbe719f73e0 514 Gene3D G3DSA:3.30.360.10 203 513 1.2E-118 T 14-10-2018 MB46_05090 bb10c5f752ae2dde714c5dbe719f73e0 514 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 31 214 2.4E-60 T 14-10-2018 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MB46_05090 bb10c5f752ae2dde714c5dbe719f73e0 514 SUPERFAMILY SSF51735 18 217 1.02E-58 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_05090 bb10c5f752ae2dde714c5dbe719f73e0 514 SUPERFAMILY SSF55347 204 512 6.54E-113 T 14-10-2018 MB46_05090 bb10c5f752ae2dde714c5dbe719f73e0 514 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 27 513 85.908 T 14-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MB46_05090 bb10c5f752ae2dde714c5dbe719f73e0 514 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 28 513 6.0E-194 T 14-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MB46_05090 bb10c5f752ae2dde714c5dbe719f73e0 514 ProSitePatterns PS00069 Glucose-6-phosphate dehydrogenase active site. 204 210 - T 14-10-2018 IPR019796 Glucose-6-phosphate dehydrogenase, active site GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MB46_05090 bb10c5f752ae2dde714c5dbe719f73e0 514 PIRSF PIRSF000110 4 514 4.9E-174 T 14-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MB46_05090 bb10c5f752ae2dde714c5dbe719f73e0 514 Gene3D G3DSA:3.40.50.720 25 202 3.3E-51 T 14-10-2018 MB46_00095 3daea541fbd4d11248678c5cfb717796 299 SUPERFAMILY SSF52833 133 294 5.93E-27 T 14-10-2018 IPR036249 Thioredoxin-like superfamily MB46_00095 3daea541fbd4d11248678c5cfb717796 299 Pfam PF13462 Thioredoxin 135 294 3.5E-21 T 14-10-2018 IPR012336 Thioredoxin-like fold MB46_00095 3daea541fbd4d11248678c5cfb717796 299 Gene3D G3DSA:3.40.30.10 95 299 6.6E-50 T 14-10-2018 MB46_14180 6724bc5bc0e5639fbbeffb9fd4cac2ae 486 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 21 383 2.6E-12 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MB46_14180 6724bc5bc0e5639fbbeffb9fd4cac2ae 486 Gene3D G3DSA:3.40.50.720 22 476 9.7E-140 T 14-10-2018 MB46_14180 6724bc5bc0e5639fbbeffb9fd4cac2ae 486 Gene3D G3DSA:3.50.50.60 63 344 9.7E-140 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_14180 6724bc5bc0e5639fbbeffb9fd4cac2ae 486 PIRSF PIRSF000362 14 482 1.2E-160 T 14-10-2018 IPR021163 Ferredoxin-NADP+ reductase, adrenodoxin-type GO:0016491|GO:0055114 Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 MB46_14180 6724bc5bc0e5639fbbeffb9fd4cac2ae 486 SUPERFAMILY SSF51971 19 344 2.0E-59 T 14-10-2018 MB46_14180 6724bc5bc0e5639fbbeffb9fd4cac2ae 486 PRINTS PR00419 Adrenodoxin reductase family signature 165 179 8.7E-16 T 14-10-2018 MB46_14180 6724bc5bc0e5639fbbeffb9fd4cac2ae 486 PRINTS PR00419 Adrenodoxin reductase family signature 94 104 8.7E-16 T 14-10-2018 MB46_14180 6724bc5bc0e5639fbbeffb9fd4cac2ae 486 PRINTS PR00419 Adrenodoxin reductase family signature 21 43 8.7E-16 T 14-10-2018 MB46_16575 f7d8e4790ca16b93a29e891ad9d989f2 452 Gene3D G3DSA:2.40.50.100 2 101 3.4E-24 T 14-10-2018 MB46_16575 f7d8e4790ca16b93a29e891ad9d989f2 452 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 226 451 5.7E-74 T 14-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 MB46_16575 f7d8e4790ca16b93a29e891ad9d989f2 452 SUPERFAMILY SSF51230 5 96 2.62E-25 T 14-10-2018 IPR011053 Single hybrid motif MB46_16575 f7d8e4790ca16b93a29e891ad9d989f2 452 Pfam PF02817 e3 binding domain 160 195 2.8E-10 T 14-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 MB46_16575 f7d8e4790ca16b93a29e891ad9d989f2 452 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 29 58 - T 14-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 MB46_16575 f7d8e4790ca16b93a29e891ad9d989f2 452 SUPERFAMILY SSF47005 154 199 1.57E-10 T 14-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 MB46_16575 f7d8e4790ca16b93a29e891ad9d989f2 452 Gene3D G3DSA:4.10.320.10 152 206 1.3E-12 T 14-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 MB46_16575 f7d8e4790ca16b93a29e891ad9d989f2 452 Gene3D G3DSA:3.30.559.10 213 449 1.9E-77 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 MB46_16575 f7d8e4790ca16b93a29e891ad9d989f2 452 Pfam PF00364 Biotin-requiring enzyme 7 78 1.4E-20 T 14-10-2018 IPR000089 Biotin/lipoyl attachment MB46_16575 f7d8e4790ca16b93a29e891ad9d989f2 452 SUPERFAMILY SSF52777 217 451 3.25E-75 T 14-10-2018 MB46_19190 75f842f040e7d2650ee0900a1624964c 135 SUPERFAMILY SSF46785 18 128 5.56E-29 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_19190 75f842f040e7d2650ee0900a1624964c 135 Pfam PF01638 HxlR-like helix-turn-helix 32 118 5.1E-26 T 14-10-2018 IPR002577 Helix-turn-helix, HxlR type MB46_19190 75f842f040e7d2650ee0900a1624964c 135 Gene3D G3DSA:1.10.10.10 3 130 1.7E-37 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_19990 75f842f040e7d2650ee0900a1624964c 135 SUPERFAMILY SSF46785 18 128 5.56E-29 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_19990 75f842f040e7d2650ee0900a1624964c 135 Pfam PF01638 HxlR-like helix-turn-helix 32 118 5.1E-26 T 14-10-2018 IPR002577 Helix-turn-helix, HxlR type MB46_19990 75f842f040e7d2650ee0900a1624964c 135 Gene3D G3DSA:1.10.10.10 3 130 1.7E-37 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_10550 ec9e58b1a1450662b85fd5779f02f0d6 260 TIGRFAM TIGR01097 PhnE: phosphonate ABC transporter, permease protein PhnE 14 259 1.3E-75 T 14-10-2018 IPR005769 ABC transporter, permease PhnE/PtxC GO:0005887|GO:0015604|GO:0015716 MB46_10550 ec9e58b1a1450662b85fd5779f02f0d6 260 SUPERFAMILY SSF161098 66 249 8.9E-34 T 14-10-2018 IPR035906 MetI-like superfamily MB46_10550 ec9e58b1a1450662b85fd5779f02f0d6 260 Gene3D G3DSA:1.10.3720.10 64 259 5.3E-30 T 14-10-2018 IPR035906 MetI-like superfamily MB46_10550 ec9e58b1a1450662b85fd5779f02f0d6 260 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 89 257 1.5E-15 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_03335 392a44be0059e52416c99e377b8fe988 132 SUPERFAMILY SSF55620 1 129 2.5E-25 T 14-10-2018 MB46_03335 392a44be0059e52416c99e377b8fe988 132 Gene3D G3DSA:3.30.479.10 1 132 1.8E-25 T 14-10-2018 IPR038418 6-pyruvoyl tetrahydropterin synthase/QueD superfamily Reactome: R-HSA-1474151 MB46_03335 392a44be0059e52416c99e377b8fe988 132 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 4 130 2.1E-19 T 14-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 MB46_14635 ececdbaf4a3e4cdad8c969569fe68e9a 68 SMART SM00530 9 64 1.2E-9 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MB46_14635 ececdbaf4a3e4cdad8c969569fe68e9a 68 Gene3D G3DSA:1.10.260.40 1 68 2.6E-15 T 14-10-2018 MB46_14635 ececdbaf4a3e4cdad8c969569fe68e9a 68 Pfam PF13560 Helix-turn-helix domain 5 61 1.1E-11 T 14-10-2018 MB46_14635 ececdbaf4a3e4cdad8c969569fe68e9a 68 SUPERFAMILY SSF47413 4 66 6.66E-14 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MB46_13540 172eb40c4784f33605db7b35c789ce9b 410 Gene3D G3DSA:3.40.640.10 75 297 2.3E-129 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MB46_13540 172eb40c4784f33605db7b35c789ce9b 410 SUPERFAMILY SSF53383 15 407 8.25E-112 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MB46_13540 172eb40c4784f33605db7b35c789ce9b 410 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 247 260 - T 14-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 MB46_13540 172eb40c4784f33605db7b35c789ce9b 410 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 210 233 5.9E-11 T 14-10-2018 MB46_13540 172eb40c4784f33605db7b35c789ce9b 410 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 127 148 5.9E-11 T 14-10-2018 MB46_13540 172eb40c4784f33605db7b35c789ce9b 410 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 174 198 5.9E-11 T 14-10-2018 MB46_13540 172eb40c4784f33605db7b35c789ce9b 410 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 241 265 5.9E-11 T 14-10-2018 MB46_13540 172eb40c4784f33605db7b35c789ce9b 410 Gene3D G3DSA:3.90.1150.10 37 402 2.3E-129 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MB46_13540 172eb40c4784f33605db7b35c789ce9b 410 Pfam PF00155 Aminotransferase class I and II 43 394 2.0E-67 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MB46_15615 043081dd749cfc831bad1677ede4376d 309 Gene3D G3DSA:1.20.1510.10 19 213 1.2E-37 T 14-10-2018 IPR027469 Cation efflux transmembrane domain superfamily MB46_15615 043081dd749cfc831bad1677ede4376d 309 SUPERFAMILY SSF161111 19 214 4.71E-50 T 14-10-2018 IPR027469 Cation efflux transmembrane domain superfamily MB46_15615 043081dd749cfc831bad1677ede4376d 309 Pfam PF01545 Cation efflux family 24 213 1.8E-36 T 14-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 MB46_15615 043081dd749cfc831bad1677ede4376d 309 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 21 298 9.6E-68 T 14-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 MB46_15615 043081dd749cfc831bad1677ede4376d 309 SUPERFAMILY SSF160240 218 296 1.96E-5 T 14-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 MB46_05210 736c1736d4969eee5548264d035bd3f7 117 Pfam PF11298 Protein of unknown function (DUF3099) 1 52 5.5E-16 T 14-10-2018 IPR021449 Protein of unknown function DUF3099 MB46_13205 39d0c557d02038c12c6b4cc2931734da 316 Pfam PF04480 Protein of unknown function (DUF559) 242 299 8.1E-6 T 14-10-2018 IPR007569 Protein of unknown function DUF559 MB46_13205 39d0c557d02038c12c6b4cc2931734da 316 Gene3D G3DSA:3.40.960.10 219 302 3.2E-11 T 14-10-2018 MB46_13205 39d0c557d02038c12c6b4cc2931734da 316 SUPERFAMILY SSF52980 198 303 1.72E-7 T 14-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 MB46_15640 edbcffa430734c4c30d243e253a1e3f4 269 Gene3D G3DSA:3.30.1240.10 82 188 2.5E-53 T 14-10-2018 MB46_15640 edbcffa430734c4c30d243e253a1e3f4 269 SUPERFAMILY SSF56784 2 263 2.36E-53 T 14-10-2018 IPR036412 HAD-like superfamily MB46_15640 edbcffa430734c4c30d243e253a1e3f4 269 Pfam PF08282 haloacid dehalogenase-like hydrolase 4 259 7.8E-47 T 14-10-2018 MB46_15640 edbcffa430734c4c30d243e253a1e3f4 269 Gene3D G3DSA:3.40.50.1000 2 260 2.5E-53 T 14-10-2018 IPR023214 HAD superfamily MB46_15640 edbcffa430734c4c30d243e253a1e3f4 269 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 3 230 1.7E-19 T 14-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 MB46_10810 b0c221f1a6af8ca5cd2e717c0c182bb6 414 Pfam PF01979 Amidohydrolase family 71 403 4.6E-15 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 MB46_10810 b0c221f1a6af8ca5cd2e717c0c182bb6 414 Gene3D G3DSA:3.20.20.140 75 378 1.3E-104 T 14-10-2018 MB46_10810 b0c221f1a6af8ca5cd2e717c0c182bb6 414 SUPERFAMILY SSF51556 74 384 3.34E-75 T 14-10-2018 IPR032466 Metal-dependent hydrolase MB46_10810 b0c221f1a6af8ca5cd2e717c0c182bb6 414 SUPERFAMILY SSF51338 13 412 3.05E-8 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 MB46_10810 b0c221f1a6af8ca5cd2e717c0c182bb6 414 PIRSF PIRSF038994 13 414 5.5E-86 T 14-10-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 MB46_10810 b0c221f1a6af8ca5cd2e717c0c182bb6 414 Gene3D G3DSA:2.30.40.10 18 410 1.3E-104 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 MB46_01175 aec360eed28fb27f53d5cea31e7346c0 962 SUPERFAMILY SSF48452 682 820 5.48E-9 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MB46_01175 aec360eed28fb27f53d5cea31e7346c0 962 SUPERFAMILY SSF48452 577 703 1.9E-5 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MB46_01175 aec360eed28fb27f53d5cea31e7346c0 962 SUPERFAMILY SSF48452 756 945 2.38E-8 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MB46_01175 aec360eed28fb27f53d5cea31e7346c0 962 Gene3D G3DSA:1.25.40.10 824 953 8.1E-7 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MB46_01175 aec360eed28fb27f53d5cea31e7346c0 962 Gene3D G3DSA:1.25.40.10 716 823 4.1E-5 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MB46_17150 697a937a915f1f98a4d38ff112ce5643 279 Pfam PF02567 Phenazine biosynthesis-like protein 10 260 1.7E-51 T 14-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 MB46_17150 697a937a915f1f98a4d38ff112ce5643 279 PIRSF PIRSF016184 2 279 8.6E-70 T 14-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 MB46_17150 697a937a915f1f98a4d38ff112ce5643 279 SUPERFAMILY SSF54506 5 278 9.25E-69 T 14-10-2018 MB46_17150 697a937a915f1f98a4d38ff112ce5643 279 Gene3D G3DSA:3.10.310.10 127 271 3.6E-78 T 14-10-2018 MB46_17150 697a937a915f1f98a4d38ff112ce5643 279 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 8 261 4.4E-51 T 14-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 MB46_17150 697a937a915f1f98a4d38ff112ce5643 279 Gene3D G3DSA:3.10.310.10 10 272 3.6E-78 T 14-10-2018 MB46_17775 b414ed87cabf06475c1c42eae6bafe14 195 Pfam PF00578 AhpC/TSA family 59 173 3.8E-18 T 14-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 MB46_17775 b414ed87cabf06475c1c42eae6bafe14 195 Gene3D G3DSA:3.40.30.10 35 195 1.2E-29 T 14-10-2018 MB46_17775 b414ed87cabf06475c1c42eae6bafe14 195 SUPERFAMILY SSF52833 3 191 1.34E-29 T 14-10-2018 IPR036249 Thioredoxin-like superfamily MB46_07085 ba21d6ceafce6568b58c89a7e8541c03 261 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 86 259 3.3E-7 T 14-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 MB46_07085 ba21d6ceafce6568b58c89a7e8541c03 261 TIGRFAM TIGR02312 HpaH: 2-oxo-hepta-3-ene-1,7-dioic acid hydratase 1 260 4.8E-110 T 14-10-2018 IPR012690 2-oxo-hepta-4-ene-1,7-dioic acid hydratase GO:0018817|GO:0019439 MB46_07085 ba21d6ceafce6568b58c89a7e8541c03 261 Gene3D G3DSA:3.90.850.10 1 260 3.1E-77 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 MB46_07085 ba21d6ceafce6568b58c89a7e8541c03 261 SUPERFAMILY SSF56529 2 260 4.43E-75 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 MB46_13725 c7d7dc4deae98c375859a6b3f4c21556 446 Pfam PF07690 Major Facilitator Superfamily 292 430 5.0E-9 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MB46_13725 c7d7dc4deae98c375859a6b3f4c21556 446 Gene3D G3DSA:1.20.1250.20 246 432 1.1E-21 T 14-10-2018 MB46_13725 c7d7dc4deae98c375859a6b3f4c21556 446 Gene3D G3DSA:1.20.1250.20 11 184 3.6E-11 T 14-10-2018 MB46_13725 c7d7dc4deae98c375859a6b3f4c21556 446 SUPERFAMILY SSF103473 13 434 2.09E-34 T 14-10-2018 IPR036259 MFS transporter superfamily MB46_12340 785ce20ca5459fd9cdf5e62ce1bde9af 564 Pfam PF00270 DEAD/DEAH box helicase 60 232 2.7E-45 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MB46_12340 785ce20ca5459fd9cdf5e62ce1bde9af 564 SUPERFAMILY SSF52540 115 398 3.94E-72 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_12340 785ce20ca5459fd9cdf5e62ce1bde9af 564 Gene3D G3DSA:3.40.50.300 258 428 2.1E-46 T 14-10-2018 MB46_12340 785ce20ca5459fd9cdf5e62ce1bde9af 564 Pfam PF00271 Helicase conserved C-terminal domain 273 382 5.8E-29 T 14-10-2018 IPR001650 Helicase, C-terminal MB46_12340 785ce20ca5459fd9cdf5e62ce1bde9af 564 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 193 201 - T 14-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site MB46_12340 785ce20ca5459fd9cdf5e62ce1bde9af 564 Gene3D G3DSA:3.40.50.300 5 250 2.6E-70 T 14-10-2018 MB46_12340 785ce20ca5459fd9cdf5e62ce1bde9af 564 SMART SM00490 301 382 7.4E-30 T 14-10-2018 IPR001650 Helicase, C-terminal MB46_12340 785ce20ca5459fd9cdf5e62ce1bde9af 564 SMART SM00487 55 265 3.3E-52 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MB46_02645 e08bf20c0550a43c10bd85e99373c365 203 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 124 135 4.2E-5 T 14-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 MB46_02645 e08bf20c0550a43c10bd85e99373c365 203 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 64 79 4.2E-5 T 14-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 MB46_02645 e08bf20c0550a43c10bd85e99373c365 203 TIGRFAM TIGR02228 sigpep_I_arch: signal peptidase I 39 173 2.8E-26 T 14-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 MB46_14035 561357b5a39053a45cf854b0407b747d 222 Gene3D G3DSA:3.40.50.12740 3 218 1.9E-71 T 14-10-2018 MB46_14035 561357b5a39053a45cf854b0407b747d 222 SMART SM00421 155 212 4.6E-25 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_14035 561357b5a39053a45cf854b0407b747d 222 SMART SM00448 3 119 5.8E-33 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MB46_14035 561357b5a39053a45cf854b0407b747d 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 188 200 4.8E-14 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_14035 561357b5a39053a45cf854b0407b747d 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 158 172 4.8E-14 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_14035 561357b5a39053a45cf854b0407b747d 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 172 188 4.8E-14 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_14035 561357b5a39053a45cf854b0407b747d 222 Pfam PF00072 Response regulator receiver domain 5 120 4.3E-27 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MB46_14035 561357b5a39053a45cf854b0407b747d 222 SUPERFAMILY SSF46894 138 219 6.8E-23 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MB46_14035 561357b5a39053a45cf854b0407b747d 222 SUPERFAMILY SSF52172 1 138 2.13E-34 T 14-10-2018 IPR011006 CheY-like superfamily MB46_14035 561357b5a39053a45cf854b0407b747d 222 Pfam PF00196 Bacterial regulatory proteins, luxR family 158 212 4.6E-19 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_04640 89483d67057993df38772528665e84ca 444 Pfam PF03471 Transporter associated domain 339 412 1.6E-14 T 14-10-2018 IPR005170 Transporter-associated domain MB46_04640 89483d67057993df38772528665e84ca 444 Pfam PF01595 Domain of unknown function DUF21 11 184 5.6E-20 T 14-10-2018 IPR002550 CNNM, transmembrane domain MB46_04640 89483d67057993df38772528665e84ca 444 Gene3D G3DSA:3.30.465.10 329 414 1.8E-21 T 14-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 MB46_04640 89483d67057993df38772528665e84ca 444 Gene3D G3DSA:3.10.580.10 178 328 2.4E-55 T 14-10-2018 MB46_04640 89483d67057993df38772528665e84ca 444 SUPERFAMILY SSF56176 335 423 4.36E-17 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 MB46_04640 89483d67057993df38772528665e84ca 444 Pfam PF00571 CBS domain 273 322 8.0E-6 T 14-10-2018 IPR000644 CBS domain MB46_04640 89483d67057993df38772528665e84ca 444 Pfam PF00571 CBS domain 202 257 6.3E-8 T 14-10-2018 IPR000644 CBS domain MB46_04640 89483d67057993df38772528665e84ca 444 SUPERFAMILY SSF54631 187 325 3.54E-32 T 14-10-2018 MB46_04640 89483d67057993df38772528665e84ca 444 SMART SM01091 337 417 5.6E-20 T 14-10-2018 IPR005170 Transporter-associated domain MB46_04640 89483d67057993df38772528665e84ca 444 SMART SM00116 274 322 15.0 T 14-10-2018 IPR000644 CBS domain MB46_04640 89483d67057993df38772528665e84ca 444 SMART SM00116 208 257 3.8E-6 T 14-10-2018 IPR000644 CBS domain MB46_05930 b8c3a0df1df43fe8f26e445b683132be 420 SUPERFAMILY SSF55031 192 292 1.96E-29 T 14-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain MB46_05930 b8c3a0df1df43fe8f26e445b683132be 420 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 23 347 6.1E-85 T 14-10-2018 IPR017439 Amidohydrolase GO:0016787 MB46_05930 b8c3a0df1df43fe8f26e445b683132be 420 Pfam PF01546 Peptidase family M20/M25/M40 81 363 5.1E-22 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 MB46_05930 b8c3a0df1df43fe8f26e445b683132be 420 SUPERFAMILY SSF53187 14 411 2.78E-71 T 14-10-2018 MB46_05930 b8c3a0df1df43fe8f26e445b683132be 420 PIRSF PIRSF005962 9 387 1.7E-99 T 14-10-2018 IPR017439 Amidohydrolase GO:0016787 MB46_05930 b8c3a0df1df43fe8f26e445b683132be 420 Gene3D G3DSA:3.30.70.360 189 305 3.4E-116 T 14-10-2018 MB46_05930 b8c3a0df1df43fe8f26e445b683132be 420 Pfam PF07687 Peptidase dimerisation domain 193 288 6.2E-14 T 14-10-2018 IPR011650 Peptidase M20, dimerisation domain MB46_05930 b8c3a0df1df43fe8f26e445b683132be 420 Gene3D G3DSA:3.40.630.10 24 378 3.4E-116 T 14-10-2018 MB46_04195 d06226c819f87df8988f5d04087af39d 187 Gene3D G3DSA:3.40.630.30 1 173 1.5E-37 T 14-10-2018 MB46_04195 d06226c819f87df8988f5d04087af39d 187 SUPERFAMILY SSF55729 8 141 3.16E-29 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase MB46_04195 d06226c819f87df8988f5d04087af39d 187 Pfam PF13302 Acetyltransferase (GNAT) domain 12 115 1.5E-15 T 14-10-2018 IPR000182 GNAT domain MB46_14765 504453a13e9389182c959d4ad703b4c8 248 Gene3D G3DSA:3.40.50.12500 1 238 1.2E-79 T 14-10-2018 MB46_09680 0066100426a854c91dcbb1d6aaf1fe64 401 PIRSF PIRSF000337 275 364 3.6E-18 T 14-10-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 MB46_09680 0066100426a854c91dcbb1d6aaf1fe64 401 PIRSF PIRSF000337 16 290 5.5E-37 T 14-10-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 MB46_09680 0066100426a854c91dcbb1d6aaf1fe64 401 Gene3D G3DSA:3.20.20.30 8 368 1.6E-58 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 MB46_09680 0066100426a854c91dcbb1d6aaf1fe64 401 Pfam PF00296 Luciferase-like monooxygenase 29 279 8.0E-19 T 14-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MB46_09680 0066100426a854c91dcbb1d6aaf1fe64 401 SUPERFAMILY SSF51679 15 359 1.16E-47 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 MB46_06560 be82e3a49aca871c994bc7556f4bf0f9 320 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 111 314 1.7E-16 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_06560 be82e3a49aca871c994bc7556f4bf0f9 320 SUPERFAMILY SSF161098 76 304 7.06E-51 T 14-10-2018 IPR035906 MetI-like superfamily MB46_06560 be82e3a49aca871c994bc7556f4bf0f9 320 Gene3D G3DSA:1.10.3720.10 72 320 4.1E-63 T 14-10-2018 IPR035906 MetI-like superfamily MB46_11510 511ac12b3c2d76439d3e8caca701781c 331 SUPERFAMILY SSF51735 4 144 2.05E-36 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_11510 511ac12b3c2d76439d3e8caca701781c 331 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 131 198 1.7E-6 T 14-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 MB46_11510 511ac12b3c2d76439d3e8caca701781c 331 SUPERFAMILY SSF55347 123 248 1.41E-21 T 14-10-2018 MB46_11510 511ac12b3c2d76439d3e8caca701781c 331 Gene3D G3DSA:3.40.50.720 1 128 1.5E-28 T 14-10-2018 MB46_11510 511ac12b3c2d76439d3e8caca701781c 331 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 4 118 2.2E-17 T 14-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 MB46_11510 511ac12b3c2d76439d3e8caca701781c 331 Gene3D G3DSA:3.30.360.10 129 328 1.5E-29 T 14-10-2018 MB46_00235 d6ade731565d1ba00cd38daf651917da 787 SUPERFAMILY SSF51445 16 403 4.95E-95 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily MB46_00235 d6ade731565d1ba00cd38daf651917da 787 SMART SM01217 676 745 1.6E-22 T 14-10-2018 IPR026891 Fibronectin type III-like domain MB46_00235 d6ade731565d1ba00cd38daf651917da 787 Pfam PF14310 Fibronectin type III-like domain 676 745 3.3E-16 T 14-10-2018 IPR026891 Fibronectin type III-like domain MB46_00235 d6ade731565d1ba00cd38daf651917da 787 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 404 639 1.4E-48 T 14-10-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 MB46_00235 d6ade731565d1ba00cd38daf651917da 787 Gene3D G3DSA:3.40.50.1700 389 640 3.9E-61 T 14-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 MB46_00235 d6ade731565d1ba00cd38daf651917da 787 Gene3D G3DSA:2.60.40.10 646 761 6.2E-23 T 14-10-2018 IPR013783 Immunoglobulin-like fold MB46_00235 d6ade731565d1ba00cd38daf651917da 787 PRINTS PR00133 Glycosyl hydrolase family 3 signature 137 156 4.4E-18 T 14-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 MB46_00235 d6ade731565d1ba00cd38daf651917da 787 PRINTS PR00133 Glycosyl hydrolase family 3 signature 214 230 4.4E-18 T 14-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 MB46_00235 d6ade731565d1ba00cd38daf651917da 787 PRINTS PR00133 Glycosyl hydrolase family 3 signature 285 303 4.4E-18 T 14-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 MB46_00235 d6ade731565d1ba00cd38daf651917da 787 PRINTS PR00133 Glycosyl hydrolase family 3 signature 183 199 4.4E-18 T 14-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 MB46_00235 d6ade731565d1ba00cd38daf651917da 787 PRINTS PR00133 Glycosyl hydrolase family 3 signature 114 130 4.4E-18 T 14-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 MB46_00235 d6ade731565d1ba00cd38daf651917da 787 Gene3D G3DSA:3.20.20.300 25 384 2.7E-98 T 14-10-2018 IPR036962 Glycoside hydrolase, family 3, N-terminal domain superfamily GO:0004553|GO:0005975 MB46_00235 d6ade731565d1ba00cd38daf651917da 787 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 37 364 8.5E-66 T 14-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 MB46_00235 d6ade731565d1ba00cd38daf651917da 787 SUPERFAMILY SSF52279 404 639 3.53E-43 T 14-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 MB46_14685 d2e24dc4183cb76ebdf60d22b7aeae04 199 Pfam PF13662 Toprim domain 80 170 1.2E-24 T 14-10-2018 IPR006171 TOPRIM domain MB46_14685 d2e24dc4183cb76ebdf60d22b7aeae04 199 SMART SM00493 79 164 1.1E-13 T 14-10-2018 IPR006171 TOPRIM domain MB46_14685 d2e24dc4183cb76ebdf60d22b7aeae04 199 Gene3D G3DSA:1.10.8.420 4 52 1.0E-20 T 14-10-2018 MB46_14685 d2e24dc4183cb76ebdf60d22b7aeae04 199 SUPERFAMILY SSF111304 2 196 3.79E-74 T 14-10-2018 IPR023627 Recombination protein RecR MB46_14685 d2e24dc4183cb76ebdf60d22b7aeae04 199 TIGRFAM TIGR00615 recR: recombination protein RecR 2 195 2.5E-84 T 14-10-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 MB46_14685 d2e24dc4183cb76ebdf60d22b7aeae04 199 Hamap MF_00017 Recombination protein RecR [recR]. 1 197 103.937 T 14-10-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 MB46_14685 d2e24dc4183cb76ebdf60d22b7aeae04 199 Gene3D G3DSA:3.40.1360.10 76 197 7.0E-48 T 14-10-2018 MB46_14685 d2e24dc4183cb76ebdf60d22b7aeae04 199 Pfam PF02132 RecR protein 38 77 3.2E-16 T 14-10-2018 IPR023628 Recombination protein RecR, C4-type zinc finger MB46_14685 d2e24dc4183cb76ebdf60d22b7aeae04 199 ProSitePatterns PS01300 RecR protein signature. 56 77 - T 14-10-2018 IPR015967 Recombination protein RecR, conserved site GO:0006281|GO:0006310 MB46_02740 f81bf7111efb1ce400a51db5e2eb07f6 258 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 88 121 - T 14-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 MB46_02740 f81bf7111efb1ce400a51db5e2eb07f6 258 SUPERFAMILY SSF53790 4 248 4.32E-62 T 14-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 MB46_02740 f81bf7111efb1ce400a51db5e2eb07f6 258 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 9 217 4.3E-40 T 14-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 MB46_02740 f81bf7111efb1ce400a51db5e2eb07f6 258 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 8 238 8.2E-72 T 14-10-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0008168|GO:0019354 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 MB46_02740 f81bf7111efb1ce400a51db5e2eb07f6 258 Gene3D G3DSA:3.40.1010.10 6 123 2.9E-37 T 14-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 MB46_02740 f81bf7111efb1ce400a51db5e2eb07f6 258 Gene3D G3DSA:3.30.950.10 130 249 1.2E-32 T 14-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 MB46_00355 b62fae6a234b3d59f0e814d9bf43ab61 439 SUPERFAMILY SSF53850 59 433 8.4E-68 T 14-10-2018 MB46_00355 b62fae6a234b3d59f0e814d9bf43ab61 439 Pfam PF13416 Bacterial extracellular solute-binding protein 66 379 9.6E-30 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein MB46_00355 b62fae6a234b3d59f0e814d9bf43ab61 439 Gene3D G3DSA:3.40.190.10 68 392 4.3E-87 T 14-10-2018 MB46_00355 b62fae6a234b3d59f0e814d9bf43ab61 439 Gene3D G3DSA:3.40.190.10 162 431 4.3E-87 T 14-10-2018 MB46_05000 a703a9eff9817ae314391870bb94a322 232 Gene3D G3DSA:3.40.50.10320 1 231 3.1E-74 T 14-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 MB46_05000 a703a9eff9817ae314391870bb94a322 232 SUPERFAMILY SSF102588 13 214 3.92E-40 T 14-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 MB46_05000 a703a9eff9817ae314391870bb94a322 232 Pfam PF02585 GlcNAc-PI de-N-acetylase 15 143 2.0E-26 T 14-10-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 MB46_07240 4045822b7b59486468782dd367c6e023 86 Pfam PF14019 Protein of unknown function (DUF4235) 6 75 1.5E-17 T 14-10-2018 IPR025329 Protein of unknown function DUF4235 MB46_08240 db347708c0b19e48125f0043d485961c 369 Gene3D G3DSA:3.40.50.2000 12 357 2.8E-91 T 14-10-2018 MB46_08240 db347708c0b19e48125f0043d485961c 369 Gene3D G3DSA:3.40.50.2000 168 351 2.8E-91 T 14-10-2018 MB46_08240 db347708c0b19e48125f0043d485961c 369 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 11 367 29.986 T 14-10-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0050511 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MB46_08240 db347708c0b19e48125f0043d485961c 369 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 11 149 1.0E-32 T 14-10-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MB46_08240 db347708c0b19e48125f0043d485961c 369 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 196 357 1.6E-28 T 14-10-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 MB46_08240 db347708c0b19e48125f0043d485961c 369 SUPERFAMILY SSF53756 11 365 1.69E-90 T 14-10-2018 MB46_08240 db347708c0b19e48125f0043d485961c 369 TIGRFAM TIGR01133 murG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 10 360 1.2E-76 T 14-10-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0050511 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MB46_12590 b220a12d3109eec1d381d3904ca3c582 129 SUPERFAMILY SSF52038 1 68 1.29E-6 T 14-10-2018 IPR035905 Barstar-like superfamily MB46_19695 4c835cd4b2c9386ed35baf334e9d88c2 227 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 35 200 6.9E-22 T 14-10-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type MB46_19695 4c835cd4b2c9386ed35baf334e9d88c2 227 SUPERFAMILY SSF109854 32 174 1.24E-32 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes MB46_19695 4c835cd4b2c9386ed35baf334e9d88c2 227 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 35 171 8.0E-20 T 14-10-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 MB46_19695 4c835cd4b2c9386ed35baf334e9d88c2 227 Gene3D G3DSA:1.20.120.450 23 176 1.2E-36 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes MB46_18965 6de703cc69d4b8945a841793402b7139 217 Pfam PF10759 Protein of unknown function (DUF2587) 42 193 3.9E-69 T 14-10-2018 IPR019695 Bacterial proteasome activator GO:0061136 MB46_13570 66056758fc962362d024b692a4b6f768 243 SUPERFAMILY SSF55729 110 228 1.17E-10 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase MB46_13570 66056758fc962362d024b692a4b6f768 243 Gene3D G3DSA:3.40.630.30 45 231 7.8E-9 T 14-10-2018 MB46_08785 bb135df4d36eb14c5ba268934a5321b9 542 Pfam PF00501 AMP-binding enzyme 27 441 8.2E-110 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 MB46_08785 bb135df4d36eb14c5ba268934a5321b9 542 Gene3D G3DSA:3.40.50.12780 12 437 3.9E-121 T 14-10-2018 MB46_08785 bb135df4d36eb14c5ba268934a5321b9 542 ProSitePatterns PS00455 Putative AMP-binding domain signature. 190 201 - T 14-10-2018 IPR020845 AMP-binding, conserved site MB46_08785 bb135df4d36eb14c5ba268934a5321b9 542 SUPERFAMILY SSF56801 17 536 4.58E-157 T 14-10-2018 MB46_08785 bb135df4d36eb14c5ba268934a5321b9 542 Gene3D G3DSA:3.30.300.30 438 539 5.8E-30 T 14-10-2018 MB46_08785 bb135df4d36eb14c5ba268934a5321b9 542 Pfam PF13193 AMP-binding enzyme C-terminal domain 450 526 4.8E-16 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain MB46_03915 bd4ef82cad76b39f3e7a0f72965b73d3 175 Gene3D G3DSA:1.10.10.10 66 111 1.1E-11 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_03915 bd4ef82cad76b39f3e7a0f72965b73d3 175 Hamap MF_01114 Regulatory protein RecX [recX]. 7 171 13.712 T 14-10-2018 IPR003783 Regulatory protein RecX GO:0006282 MB46_03915 bd4ef82cad76b39f3e7a0f72965b73d3 175 Pfam PF02631 RecX family 42 166 5.6E-28 T 14-10-2018 IPR003783 Regulatory protein RecX GO:0006282 MB46_10950 f0e916a1f557beccb210c681dcbe2d8b 483 SUPERFAMILY SSF51419 57 337 5.72E-64 T 14-10-2018 IPR029066 PLP-binding barrel MB46_10950 f0e916a1f557beccb210c681dcbe2d8b 483 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 46 481 36.16 T 14-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MB46_10950 f0e916a1f557beccb210c681dcbe2d8b 483 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 69 336 2.1E-53 T 14-10-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 MB46_10950 f0e916a1f557beccb210c681dcbe2d8b 483 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 276 289 - T 14-10-2018 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site MB46_10950 f0e916a1f557beccb210c681dcbe2d8b 483 SUPERFAMILY SSF50621 310 480 4.19E-45 T 14-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 MB46_10950 f0e916a1f557beccb210c681dcbe2d8b 483 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 94 112 - T 14-10-2018 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site MB46_10950 f0e916a1f557beccb210c681dcbe2d8b 483 Gene3D G3DSA:3.20.20.10 65 336 1.4E-154 T 14-10-2018 IPR029066 PLP-binding barrel MB46_10950 f0e916a1f557beccb210c681dcbe2d8b 483 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 326 345 1.2E-12 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 MB46_10950 f0e916a1f557beccb210c681dcbe2d8b 483 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 94 112 1.2E-12 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 MB46_10950 f0e916a1f557beccb210c681dcbe2d8b 483 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 114 126 1.2E-12 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 MB46_10950 f0e916a1f557beccb210c681dcbe2d8b 483 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 438 451 1.2E-12 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 MB46_10950 f0e916a1f557beccb210c681dcbe2d8b 483 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 237 250 1.2E-12 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 MB46_10950 f0e916a1f557beccb210c681dcbe2d8b 483 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 37 480 7.1E-126 T 14-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MB46_10950 f0e916a1f557beccb210c681dcbe2d8b 483 Gene3D G3DSA:2.40.37.10 44 477 1.4E-154 T 14-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 MB46_10950 f0e916a1f557beccb210c681dcbe2d8b 483 PRINTS PR01181 Diaminopimelate decarboxylase signature 448 470 9.2E-23 T 14-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MB46_10950 f0e916a1f557beccb210c681dcbe2d8b 483 PRINTS PR01181 Diaminopimelate decarboxylase signature 365 383 9.2E-23 T 14-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MB46_10950 f0e916a1f557beccb210c681dcbe2d8b 483 PRINTS PR01181 Diaminopimelate decarboxylase signature 112 129 9.2E-23 T 14-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MB46_10950 f0e916a1f557beccb210c681dcbe2d8b 483 PRINTS PR01181 Diaminopimelate decarboxylase signature 201 210 9.2E-23 T 14-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MB46_10950 f0e916a1f557beccb210c681dcbe2d8b 483 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 360 438 1.4E-14 T 14-10-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 MB46_01625 b769d7b4b0da9b9d7626758c8bf52df0 279 Pfam PF13354 Beta-lactamase enzyme family 27 235 4.1E-32 T 14-10-2018 MB46_01625 b769d7b4b0da9b9d7626758c8bf52df0 279 SUPERFAMILY SSF56601 18 235 1.17E-32 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like MB46_01625 b769d7b4b0da9b9d7626758c8bf52df0 279 Gene3D G3DSA:3.40.710.10 8 276 9.2E-51 T 14-10-2018 MB46_10160 1988d755ff33adb28ec88f591646096f 334 Gene3D G3DSA:3.40.960.10 232 329 3.6E-5 T 14-10-2018 MB46_10160 1988d755ff33adb28ec88f591646096f 334 Pfam PF13338 Transcriptional regulator, AbiEi antitoxin 11 40 1.4E-5 T 14-10-2018 IPR025159 Transcriptional regulator, AbiEi antitoxin MB46_03095 c8587f51708a048c12a21e9727ebf305 349 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 133 1.9E-30 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MB46_03095 c8587f51708a048c12a21e9727ebf305 349 Gene3D G3DSA:3.40.50.720 154 287 8.3E-97 T 14-10-2018 MB46_03095 c8587f51708a048c12a21e9727ebf305 349 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 14-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 MB46_03095 c8587f51708a048c12a21e9727ebf305 349 SUPERFAMILY SSF50129 1 174 6.92E-49 T 14-10-2018 IPR011032 GroES-like superfamily MB46_03095 c8587f51708a048c12a21e9727ebf305 349 SUPERFAMILY SSF51735 143 302 3.07E-32 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_03095 c8587f51708a048c12a21e9727ebf305 349 Gene3D G3DSA:3.90.180.10 21 332 8.3E-97 T 14-10-2018 MB46_03095 c8587f51708a048c12a21e9727ebf305 349 Pfam PF00107 Zinc-binding dehydrogenase 175 302 2.4E-24 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 MB46_17275 53fce74130d56c4fe6362592b1af98a3 323 SUPERFAMILY SSF51730 48 306 1.02E-43 T 14-10-2018 IPR029041 FAD-linked oxidoreductase-like MB46_17275 53fce74130d56c4fe6362592b1af98a3 323 Gene3D G3DSA:3.20.20.530 30 312 1.6E-60 T 14-10-2018 MB46_17275 53fce74130d56c4fe6362592b1af98a3 323 Pfam PF01619 Proline dehydrogenase 59 289 1.2E-20 T 14-10-2018 IPR002872 Proline dehydrogenase domain KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922|Reactome: R-HSA-70688 MB46_09575 ca72e15ea624cd31d4b3138a8f86a433 213 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 26 186 21.736 T 14-10-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 MB46_09575 ca72e15ea624cd31d4b3138a8f86a433 213 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 27 186 8.1E-37 T 14-10-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 MB46_09575 ca72e15ea624cd31d4b3138a8f86a433 213 Gene3D G3DSA:2.40.30.60 26 110 1.1E-19 T 14-10-2018 IPR036976 RimM, N-terminal domain superfamily GO:0006364 MB46_09575 ca72e15ea624cd31d4b3138a8f86a433 213 SUPERFAMILY SSF50447 27 109 9.54E-18 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily MB46_09575 ca72e15ea624cd31d4b3138a8f86a433 213 Pfam PF01782 RimM N-terminal domain 28 109 1.4E-20 T 14-10-2018 IPR002676 RimM, N-terminal GO:0006364 MB46_09575 ca72e15ea624cd31d4b3138a8f86a433 213 Gene3D G3DSA:2.30.30.240 113 191 1.5E-8 T 14-10-2018 MB46_09575 ca72e15ea624cd31d4b3138a8f86a433 213 SUPERFAMILY SSF50346 117 186 4.71E-14 T 14-10-2018 IPR011033 PRC-barrel-like superfamily MB46_01645 f1519c04c22cd3841ae3cd6cf924cd32 307 Gene3D G3DSA:1.10.3720.10 91 301 4.6E-22 T 14-10-2018 IPR035906 MetI-like superfamily MB46_01645 f1519c04c22cd3841ae3cd6cf924cd32 307 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 29 79 6.0E-10 T 14-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain MB46_01645 f1519c04c22cd3841ae3cd6cf924cd32 307 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 120 305 3.7E-24 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_01645 f1519c04c22cd3841ae3cd6cf924cd32 307 SUPERFAMILY SSF161098 98 288 4.58E-28 T 14-10-2018 IPR035906 MetI-like superfamily MB46_03860 cf9291fe97d451ca58c7e08973ad5ad8 252 PIRSF PIRSF000161 3 251 1.8E-63 T 14-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MB46_03860 cf9291fe97d451ca58c7e08973ad5ad8 252 SUPERFAMILY SSF51735 3 136 5.54E-35 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_03860 cf9291fe97d451ca58c7e08973ad5ad8 252 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 112 239 1.4E-28 T 14-10-2018 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MB46_03860 cf9291fe97d451ca58c7e08973ad5ad8 252 Gene3D G3DSA:3.30.360.10 110 218 3.9E-79 T 14-10-2018 MB46_03860 cf9291fe97d451ca58c7e08973ad5ad8 252 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 5 249 28.454 T 14-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MB46_03860 cf9291fe97d451ca58c7e08973ad5ad8 252 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 6 109 1.2E-24 T 14-10-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MB46_03860 cf9291fe97d451ca58c7e08973ad5ad8 252 SUPERFAMILY SSF55347 110 219 1.02E-37 T 14-10-2018 MB46_03860 cf9291fe97d451ca58c7e08973ad5ad8 252 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 43 238 3.5E-52 T 14-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MB46_03860 cf9291fe97d451ca58c7e08973ad5ad8 252 Gene3D G3DSA:3.40.50.720 7 238 3.9E-79 T 14-10-2018 MB46_03860 cf9291fe97d451ca58c7e08973ad5ad8 252 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 131 148 - T 14-10-2018 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MB46_11255 7ad1468f9b53b3c1a428aa47131f116d 470 SUPERFAMILY SSF53383 35 428 8.47E-74 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MB46_11255 7ad1468f9b53b3c1a428aa47131f116d 470 Gene3D G3DSA:3.90.1150.10 35 420 1.5E-98 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MB46_11255 7ad1468f9b53b3c1a428aa47131f116d 470 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 232 251 - T 14-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site MB46_11255 7ad1468f9b53b3c1a428aa47131f116d 470 Gene3D G3DSA:3.40.640.10 55 316 1.5E-98 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MB46_11255 7ad1468f9b53b3c1a428aa47131f116d 470 Pfam PF00266 Aminotransferase class-V 38 419 3.6E-80 T 14-10-2018 IPR000192 Aminotransferase class V domain MB46_00650 22b7cf5a9f3b59b4c5c72159f1e9537f 677 SUPERFAMILY SSF50939 57 419 7.29E-85 T 14-10-2018 IPR036278 Sialidase superfamily KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 MB46_00650 22b7cf5a9f3b59b4c5c72159f1e9537f 677 Pfam PF13088 BNR repeat-like domain 96 398 9.5E-23 T 14-10-2018 IPR011040 Sialidase KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 MB46_00650 22b7cf5a9f3b59b4c5c72159f1e9537f 677 Gene3D G3DSA:2.120.10.10 44 426 2.8E-113 T 14-10-2018 MB46_19435 271484fd8ae28e66a6b8979024f801a5 232 SUPERFAMILY SSF89392 11 222 7.45E-19 T 14-10-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX MB46_19435 271484fd8ae28e66a6b8979024f801a5 232 Pfam PF07161 LppX_LprAFG lipoprotein 11 221 4.1E-8 T 14-10-2018 IPR009830 LppX/LprAFG lipoprotein family MB46_19435 271484fd8ae28e66a6b8979024f801a5 232 Gene3D G3DSA:2.50.20.20 3 222 7.6E-11 T 14-10-2018 MB46_10845 9f9dcb3e8407cbb92895dda04537ff6d 297 Pfam PF00231 ATP synthase 5 294 7.1E-83 T 14-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MB46_10845 9f9dcb3e8407cbb92895dda04537ff6d 297 SUPERFAMILY SSF52943 3 294 6.93E-78 T 14-10-2018 IPR035968 ATP synthase, F1 complex, gamma subunit superfamily GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MB46_10845 9f9dcb3e8407cbb92895dda04537ff6d 297 ProSitePatterns PS00153 ATP synthase gamma subunit signature. 280 293 - T 14-10-2018 IPR023632 ATP synthase, F1 complex, gamma subunit conserved site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MB46_10845 9f9dcb3e8407cbb92895dda04537ff6d 297 Hamap MF_00815 ATP synthase gamma chain [atpG]. 2 294 32.23 T 14-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MB46_10845 9f9dcb3e8407cbb92895dda04537ff6d 297 Gene3D G3DSA:1.10.287.80 9 290 1.8E-86 T 14-10-2018 MB46_10845 9f9dcb3e8407cbb92895dda04537ff6d 297 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 3 294 1.3E-87 T 14-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MB46_10845 9f9dcb3e8407cbb92895dda04537ff6d 297 Gene3D G3DSA:3.40.1380.10 61 213 1.8E-86 T 14-10-2018 MB46_10845 9f9dcb3e8407cbb92895dda04537ff6d 297 PRINTS PR00126 ATP synthase gamma subunit signature 74 93 9.3E-31 T 14-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MB46_10845 9f9dcb3e8407cbb92895dda04537ff6d 297 PRINTS PR00126 ATP synthase gamma subunit signature 272 293 9.3E-31 T 14-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MB46_10845 9f9dcb3e8407cbb92895dda04537ff6d 297 PRINTS PR00126 ATP synthase gamma subunit signature 241 260 9.3E-31 T 14-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MB46_10845 9f9dcb3e8407cbb92895dda04537ff6d 297 PRINTS PR00126 ATP synthase gamma subunit signature 171 188 9.3E-31 T 14-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MB46_11810 46366c9c9ea48c643d7cf99cdbe4001e 258 Pfam PF04012 PspA/IM30 family 5 235 1.7E-40 T 14-10-2018 IPR007157 PspA/IM30 MB46_01290 7e7cb0de807a26bed1b84801cdce9f14 580 Gene3D G3DSA:3.40.50.10440 12 180 1.5E-50 T 14-10-2018 MB46_01290 7e7cb0de807a26bed1b84801cdce9f14 580 Pfam PF02734 DAK2 domain 390 565 1.9E-45 T 14-10-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 MB46_01290 7e7cb0de807a26bed1b84801cdce9f14 580 Pfam PF02733 Dak1 domain 18 326 3.8E-105 T 14-10-2018 IPR004006 DhaK domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 MB46_01290 7e7cb0de807a26bed1b84801cdce9f14 580 TIGRFAM TIGR02365 dha_L_ycgS: dihydroxyacetone kinase, L subunit 368 565 2.1E-41 T 14-10-2018 IPR012737 Dihydroxyacetone kinase, subunit L GO:0016772 KEGG: 00561+2.7.1.121 MB46_01290 7e7cb0de807a26bed1b84801cdce9f14 580 Gene3D G3DSA:3.30.1180.20 183 331 1.8E-42 T 14-10-2018 MB46_01290 7e7cb0de807a26bed1b84801cdce9f14 580 SMART SM01120 389 567 6.1E-56 T 14-10-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 MB46_01290 7e7cb0de807a26bed1b84801cdce9f14 580 SUPERFAMILY SSF82549 11 329 4.71E-104 T 14-10-2018 MB46_01290 7e7cb0de807a26bed1b84801cdce9f14 580 SUPERFAMILY SSF101473 366 566 8.5E-44 T 14-10-2018 IPR036117 DhaL domain superfamily GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 MB46_01290 7e7cb0de807a26bed1b84801cdce9f14 580 Gene3D G3DSA:1.25.40.340 361 571 8.4E-51 T 14-10-2018 IPR036117 DhaL domain superfamily GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 MB46_08570 2a0dc897ac8fa88db9b0ae371bcabdc5 208 Gene3D G3DSA:3.10.290.10 94 193 5.9E-62 T 14-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 MB46_08570 2a0dc897ac8fa88db9b0ae371bcabdc5 208 Gene3D G3DSA:1.10.1050.10 11 208 5.9E-62 T 14-10-2018 MB46_08570 2a0dc897ac8fa88db9b0ae371bcabdc5 208 SUPERFAMILY SSF55174 12 208 7.85E-52 T 14-10-2018 MB46_08570 2a0dc897ac8fa88db9b0ae371bcabdc5 208 ProSitePatterns PS00632 Ribosomal protein S4 signature. 93 117 - T 14-10-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MB46_08570 2a0dc897ac8fa88db9b0ae371bcabdc5 208 SMART SM00363 95 155 1.4E-12 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MB46_08570 2a0dc897ac8fa88db9b0ae371bcabdc5 208 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 9 94 2.1E-21 T 14-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 MB46_08570 2a0dc897ac8fa88db9b0ae371bcabdc5 208 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 10 208 2.9E-63 T 14-10-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 MB46_08570 2a0dc897ac8fa88db9b0ae371bcabdc5 208 Pfam PF01479 S4 domain 96 142 1.6E-14 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MB46_08570 2a0dc897ac8fa88db9b0ae371bcabdc5 208 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 6 208 30.853 T 14-10-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 MB46_08570 2a0dc897ac8fa88db9b0ae371bcabdc5 208 SMART SM01390 8 94 3.2E-34 T 14-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 MB46_18440 87bf7d68b1ad4bbbd17ee3219fc91a84 63 Pfam PF10031 Small integral membrane protein (DUF2273) 4 44 4.5E-10 T 14-10-2018 IPR018730 Protein of unknown function DUF2273 MB46_06065 e998ca94030d9a7c97fdafba39efab43 351 Gene3D G3DSA:1.10.3470.10 24 350 8.3E-89 T 14-10-2018 IPR037294 ABC transporter, BtuC-like MB46_06065 e998ca94030d9a7c97fdafba39efab43 351 Pfam PF01032 FecCD transport family 36 345 2.9E-86 T 14-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 MB46_06065 e998ca94030d9a7c97fdafba39efab43 351 SUPERFAMILY SSF81345 25 345 2.22E-77 T 14-10-2018 IPR037294 ABC transporter, BtuC-like MB46_03695 a3a0aeb3bb524c9130340a82b35b299b 176 Pfam PF10400 Virulence activator alpha C-term 91 175 1.9E-21 T 14-10-2018 IPR018309 Transcription regulator PadR, C-terminal MB46_03695 a3a0aeb3bb524c9130340a82b35b299b 176 SUPERFAMILY SSF46785 3 175 1.44E-34 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_03695 a3a0aeb3bb524c9130340a82b35b299b 176 Gene3D G3DSA:1.10.10.10 1 84 8.0E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_03695 a3a0aeb3bb524c9130340a82b35b299b 176 Pfam PF03551 Transcriptional regulator PadR-like family 7 78 2.1E-8 T 14-10-2018 IPR005149 Transcription regulator PadR, N-terminal MB46_09585 5f2a799655e90904987168f2bc626d6a 135 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 2 77 23.817 T 14-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_09585 5f2a799655e90904987168f2bc626d6a 135 Pfam PF00886 Ribosomal protein S16 9 67 1.1E-23 T 14-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_09585 5f2a799655e90904987168f2bc626d6a 135 SUPERFAMILY SSF54565 2 94 2.22E-34 T 14-10-2018 IPR023803 Ribosomal protein S16 domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_09585 5f2a799655e90904987168f2bc626d6a 135 TIGRFAM TIGR00002 S16: ribosomal protein bS16 3 79 4.6E-32 T 14-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_09585 5f2a799655e90904987168f2bc626d6a 135 ProSitePatterns PS00732 Ribosomal protein S16 signature. 3 12 - T 14-10-2018 IPR020592 Ribosomal protein S16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MB46_09585 5f2a799655e90904987168f2bc626d6a 135 Gene3D G3DSA:3.30.1320.10 1 135 4.6E-31 T 14-10-2018 IPR023803 Ribosomal protein S16 domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_10410 360a6c05127ee0b505ff59de4aca02c7 832 SUPERFAMILY SSF48371 380 561 5.67E-5 T 14-10-2018 IPR016024 Armadillo-type fold MB46_10410 360a6c05127ee0b505ff59de4aca02c7 832 TIGRFAM TIGR01760 tape_meas_TP901: phage tail tape measure protein, TP901 family, core region 68 270 3.4E-13 T 14-10-2018 IPR010090 Phage tail tape measure protein MB46_10410 360a6c05127ee0b505ff59de4aca02c7 832 Pfam PF10145 Phage-related minor tail protein 81 178 1.3E-9 T 14-10-2018 IPR010090 Phage tail tape measure protein MB46_04335 4afb91020947e6979d4050d95f8c3dec 533 Gene3D G3DSA:3.30.379.10 1 124 5.0E-31 T 14-10-2018 IPR029018 Beta-hexosaminidase-like, domain 2 MB46_04335 4afb91020947e6979d4050d95f8c3dec 533 Gene3D G3DSA:3.20.20.80 127 471 1.7E-138 T 14-10-2018 MB46_04335 4afb91020947e6979d4050d95f8c3dec 533 SUPERFAMILY SSF51445 128 484 3.07E-117 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily MB46_04335 4afb91020947e6979d4050d95f8c3dec 533 PIRSF PIRSF001093 54 515 3.0E-74 T 14-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 MB46_04335 4afb91020947e6979d4050d95f8c3dec 533 Pfam PF02838 Glycosyl hydrolase family 20, domain 2 3 124 2.4E-19 T 14-10-2018 IPR015882 Beta-hexosaminidase, bacterial type, N-terminal MB46_04335 4afb91020947e6979d4050d95f8c3dec 533 PRINTS PR00738 Glycosyl hydrolase family 20 signature 222 239 7.0E-44 T 14-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 MB46_04335 4afb91020947e6979d4050d95f8c3dec 533 PRINTS PR00738 Glycosyl hydrolase family 20 signature 435 451 7.0E-44 T 14-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 MB46_04335 4afb91020947e6979d4050d95f8c3dec 533 PRINTS PR00738 Glycosyl hydrolase family 20 signature 80 100 7.0E-44 T 14-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 MB46_04335 4afb91020947e6979d4050d95f8c3dec 533 PRINTS PR00738 Glycosyl hydrolase family 20 signature 453 470 7.0E-44 T 14-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 MB46_04335 4afb91020947e6979d4050d95f8c3dec 533 PRINTS PR00738 Glycosyl hydrolase family 20 signature 122 139 7.0E-44 T 14-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 MB46_04335 4afb91020947e6979d4050d95f8c3dec 533 PRINTS PR00738 Glycosyl hydrolase family 20 signature 151 172 7.0E-44 T 14-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 MB46_04335 4afb91020947e6979d4050d95f8c3dec 533 PRINTS PR00738 Glycosyl hydrolase family 20 signature 291 304 7.0E-44 T 14-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 MB46_04335 4afb91020947e6979d4050d95f8c3dec 533 Pfam PF00728 Glycosyl hydrolase family 20, catalytic domain 128 471 5.0E-109 T 14-10-2018 IPR015883 Glycoside hydrolase family 20, catalytic domain GO:0004553|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883 MB46_04335 4afb91020947e6979d4050d95f8c3dec 533 SUPERFAMILY SSF55545 2 127 8.77E-21 T 14-10-2018 IPR029018 Beta-hexosaminidase-like, domain 2 MB46_04005 fddf14abfa8fa0bbc1d27066e1dfc6d7 64 Pfam PF01632 Ribosomal protein L35 2 62 9.5E-25 T 14-10-2018 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_04005 fddf14abfa8fa0bbc1d27066e1dfc6d7 64 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 17.984 T 14-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 MB46_04005 fddf14abfa8fa0bbc1d27066e1dfc6d7 64 Gene3D G3DSA:2.40.50.530 1 63 6.4E-24 T 14-10-2018 MB46_04005 fddf14abfa8fa0bbc1d27066e1dfc6d7 64 SUPERFAMILY SSF143034 2 63 3.66E-23 T 14-10-2018 IPR037229 Ribosomal protein L35 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_04005 fddf14abfa8fa0bbc1d27066e1dfc6d7 64 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 62 1.2E-24 T 14-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 MB46_04005 fddf14abfa8fa0bbc1d27066e1dfc6d7 64 ProSitePatterns PS00936 Ribosomal protein L35 signature. 5 31 - T 14-10-2018 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MB46_04005 fddf14abfa8fa0bbc1d27066e1dfc6d7 64 PRINTS PR00064 Ribosomal protein L35 signature 36 54 1.4E-16 T 14-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 MB46_04005 fddf14abfa8fa0bbc1d27066e1dfc6d7 64 PRINTS PR00064 Ribosomal protein L35 signature 3 20 1.4E-16 T 14-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 MB46_04005 fddf14abfa8fa0bbc1d27066e1dfc6d7 64 PRINTS PR00064 Ribosomal protein L35 signature 21 35 1.4E-16 T 14-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 MB46_06530 175a1819dcd67e240b2dbcc6802eceab 427 Pfam PF01546 Peptidase family M20/M25/M40 83 410 2.0E-27 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 MB46_06530 175a1819dcd67e240b2dbcc6802eceab 427 Gene3D G3DSA:3.40.630.10 20 407 3.8E-119 T 14-10-2018 MB46_06530 175a1819dcd67e240b2dbcc6802eceab 427 TIGRFAM TIGR01879 hydantase: amidase, hydantoinase/carbamoylase family 15 411 1.3E-83 T 14-10-2018 IPR010158 Amidase, carbamoylase-type GO:0016813 MB46_06530 175a1819dcd67e240b2dbcc6802eceab 427 SUPERFAMILY SSF53187 12 413 8.12E-70 T 14-10-2018 MB46_06530 175a1819dcd67e240b2dbcc6802eceab 427 SUPERFAMILY SSF55031 217 329 1.06E-19 T 14-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain MB46_06530 175a1819dcd67e240b2dbcc6802eceab 427 PIRSF PIRSF001235 8 416 1.8E-108 T 14-10-2018 IPR010158 Amidase, carbamoylase-type GO:0016813 MB46_06530 175a1819dcd67e240b2dbcc6802eceab 427 Gene3D G3DSA:3.30.70.360 217 331 3.8E-119 T 14-10-2018 MB46_13430 2bebf70f4fa2f79075b21ea746929a29 278 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 6 191 4.3E-68 T 14-10-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_13430 2bebf70f4fa2f79075b21ea746929a29 278 SUPERFAMILY SSF52166 6 193 7.46E-69 T 14-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 MB46_13430 2bebf70f4fa2f79075b21ea746929a29 278 Gene3D G3DSA:3.40.1370.10 2 198 6.1E-67 T 14-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 MB46_13430 2bebf70f4fa2f79075b21ea746929a29 278 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 2 197 31.008 T 14-10-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_13430 2bebf70f4fa2f79075b21ea746929a29 278 Pfam PF00573 Ribosomal protein L4/L1 family 6 191 2.8E-60 T 14-10-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 MB46_00980 42386b4565fb4b7e6f74569dfd2b6a3b 375 Gene3D G3DSA:3.90.1150.10 271 375 5.9E-36 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MB46_00980 42386b4565fb4b7e6f74569dfd2b6a3b 375 TIGRFAM TIGR01366 serC_3: putative phosphoserine aminotransferase 15 374 1.7E-184 T 14-10-2018 IPR006272 Phosphoserine aminotransferase, Mycobacterial-type GO:0004648|GO:0006564|GO:0009058 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52 MB46_00980 42386b4565fb4b7e6f74569dfd2b6a3b 375 PIRSF PIRSF000525 6 375 3.8E-73 T 14-10-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 MB46_00980 42386b4565fb4b7e6f74569dfd2b6a3b 375 Pfam PF00266 Aminotransferase class-V 148 334 1.4E-12 T 14-10-2018 IPR000192 Aminotransferase class V domain MB46_00980 42386b4565fb4b7e6f74569dfd2b6a3b 375 SUPERFAMILY SSF53383 20 373 6.03E-69 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MB46_00980 42386b4565fb4b7e6f74569dfd2b6a3b 375 Gene3D G3DSA:3.40.640.10 30 269 1.4E-51 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MB46_12625 dfc5f0a2d8f9e5d9aa789a795ea8ab5c 188 TIGRFAM TIGR03847 TIGR03847: conserved hypothetical protein 4 185 3.5E-70 T 14-10-2018 IPR021441 Protein of unknown function DUF3090 MB46_12625 dfc5f0a2d8f9e5d9aa789a795ea8ab5c 188 Pfam PF11290 Protein of unknown function (DUF3090) 6 183 8.7E-62 T 14-10-2018 IPR021441 Protein of unknown function DUF3090 MB46_13365 5f3e60def607576362447909f9f9f010 178 PRINTS PR00059 Ribosomal protein L6 signature 141 162 4.9E-32 T 14-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 MB46_13365 5f3e60def607576362447909f9f9f010 178 PRINTS PR00059 Ribosomal protein L6 signature 99 115 4.9E-32 T 14-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 MB46_13365 5f3e60def607576362447909f9f9f010 178 PRINTS PR00059 Ribosomal protein L6 signature 71 96 4.9E-32 T 14-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 MB46_13365 5f3e60def607576362447909f9f9f010 178 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 176 5.1E-73 T 14-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 MB46_13365 5f3e60def607576362447909f9f9f010 178 Pfam PF00347 Ribosomal protein L6 11 82 7.9E-18 T 14-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MB46_13365 5f3e60def607576362447909f9f9f010 178 Pfam PF00347 Ribosomal protein L6 90 164 2.5E-18 T 14-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MB46_13365 5f3e60def607576362447909f9f9f010 178 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 176 37.625 T 14-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 MB46_13365 5f3e60def607576362447909f9f9f010 178 Gene3D G3DSA:3.90.930.12 83 178 2.6E-39 T 14-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MB46_13365 5f3e60def607576362447909f9f9f010 178 SUPERFAMILY SSF56053 83 176 2.49E-35 T 14-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MB46_13365 5f3e60def607576362447909f9f9f010 178 Gene3D G3DSA:3.90.930.12 1 82 8.9E-30 T 14-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MB46_13365 5f3e60def607576362447909f9f9f010 178 SUPERFAMILY SSF56053 1 82 6.94E-26 T 14-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MB46_13365 5f3e60def607576362447909f9f9f010 178 PIRSF PIRSF002162 1 177 6.7E-48 T 14-10-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MB46_13365 5f3e60def607576362447909f9f9f010 178 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 154 162 - T 14-10-2018 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MB46_09485 3720df28e684facee737ae36999db076 81 Gene3D G3DSA:1.10.1200.10 2 79 2.8E-23 T 14-10-2018 IPR036736 ACP-like superfamily MB46_09485 3720df28e684facee737ae36999db076 81 SUPERFAMILY SSF47336 3 79 2.88E-19 T 14-10-2018 IPR036736 ACP-like superfamily MB46_09485 3720df28e684facee737ae36999db076 81 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 37 77 2.0E-14 T 14-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 MB46_09485 3720df28e684facee737ae36999db076 81 Pfam PF00550 Phosphopantetheine attachment site 11 76 5.9E-13 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain MB46_09485 3720df28e684facee737ae36999db076 81 Hamap MF_01217 Acyl carrier protein [acpP]. 6 80 16.564 T 14-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 MB46_12230 78c5660c5c5b6f14c28449ef09da942b 131 SUPERFAMILY SSF51306 12 128 2.79E-23 T 14-10-2018 IPR036286 LexA/Signal peptidase-like superfamily MB46_12230 78c5660c5c5b6f14c28449ef09da942b 131 Pfam PF00717 Peptidase S24-like 45 96 1.6E-10 T 14-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C MB46_12230 78c5660c5c5b6f14c28449ef09da942b 131 Gene3D G3DSA:2.10.109.10 15 131 8.7E-33 T 14-10-2018 MB46_12230 78c5660c5c5b6f14c28449ef09da942b 131 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 81 93 2.9E-7 T 14-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 MB46_12230 78c5660c5c5b6f14c28449ef09da942b 131 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 53 64 2.9E-7 T 14-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 MB46_12230 78c5660c5c5b6f14c28449ef09da942b 131 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 42 52 2.9E-7 T 14-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 MB46_00830 5a3da32d34d32bc1226ac77af8ad2f8f 497 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 256 263 - T 14-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 MB46_00830 5a3da32d34d32bc1226ac77af8ad2f8f 497 Gene3D G3DSA:3.40.605.10 17 485 3.4E-154 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 MB46_00830 5a3da32d34d32bc1226ac77af8ad2f8f 497 Pfam PF00171 Aldehyde dehydrogenase family 26 487 2.6E-150 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 MB46_00830 5a3da32d34d32bc1226ac77af8ad2f8f 497 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 285 296 - T 14-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 MB46_00830 5a3da32d34d32bc1226ac77af8ad2f8f 497 SUPERFAMILY SSF53720 6 490 1.44E-145 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 MB46_00830 5a3da32d34d32bc1226ac77af8ad2f8f 497 Gene3D G3DSA:3.40.309.10 261 456 3.4E-154 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 MB46_14585 89951bb01538520bbc99526d647edf0b 318 Gene3D G3DSA:3.90.226.10 12 257 1.1E-80 T 14-10-2018 MB46_14585 89951bb01538520bbc99526d647edf0b 318 TIGRFAM TIGR01929 menB: naphthoate synthase 51 314 7.6E-117 T 14-10-2018 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837 MB46_14585 89951bb01538520bbc99526d647edf0b 318 Pfam PF00378 Enoyl-CoA hydratase/isomerase 53 312 7.2E-51 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 MB46_14585 89951bb01538520bbc99526d647edf0b 318 SUPERFAMILY SSF52096 51 314 1.37E-70 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MB46_14585 89951bb01538520bbc99526d647edf0b 318 Gene3D G3DSA:1.10.12.10 258 306 1.2E-27 T 14-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal MB46_14585 89951bb01538520bbc99526d647edf0b 318 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 155 175 - T 14-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 MB46_14585 89951bb01538520bbc99526d647edf0b 318 Hamap MF_01934 1,4-dihydroxy-2-naphthoyl-CoA synthase [menB]. 20 317 52.581 T 14-10-2018 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837 MB46_14045 c3f1f430d77f92ba7756b5ae06d2d592 238 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 5 14 - T 14-10-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824 MB46_14045 c3f1f430d77f92ba7756b5ae06d2d592 238 PIRSF PIRSF000709 2 157 8.7E-6 T 14-10-2018 MB46_14045 c3f1f430d77f92ba7756b5ae06d2d592 238 Gene3D G3DSA:3.40.50.1240 1 189 9.1E-33 T 14-10-2018 IPR029033 Histidine phosphatase superfamily MB46_14045 c3f1f430d77f92ba7756b5ae06d2d592 238 SUPERFAMILY SSF53254 2 198 1.8E-35 T 14-10-2018 IPR029033 Histidine phosphatase superfamily MB46_14045 c3f1f430d77f92ba7756b5ae06d2d592 238 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 3 186 2.8E-36 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MB46_14045 c3f1f430d77f92ba7756b5ae06d2d592 238 SMART SM00855 2 154 2.3E-15 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MB46_05340 a23c93e0ce738b435443166ed91cfc55 434 PIRSF PIRSF036696 259 434 1.0E-7 T 14-10-2018 MB46_05340 a23c93e0ce738b435443166ed91cfc55 434 PIRSF PIRSF036696 31 237 2.4E-29 T 14-10-2018 MB46_05340 a23c93e0ce738b435443166ed91cfc55 434 Gene3D G3DSA:3.40.630.10 3 200 6.3E-48 T 14-10-2018 MB46_05340 a23c93e0ce738b435443166ed91cfc55 434 Pfam PF01546 Peptidase family M20/M25/M40 79 431 3.5E-32 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 MB46_05340 a23c93e0ce738b435443166ed91cfc55 434 SUPERFAMILY SSF55031 197 330 6.43E-12 T 14-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain MB46_05340 a23c93e0ce738b435443166ed91cfc55 434 Pfam PF07687 Peptidase dimerisation domain 194 330 2.6E-17 T 14-10-2018 IPR011650 Peptidase M20, dimerisation domain MB46_05340 a23c93e0ce738b435443166ed91cfc55 434 SUPERFAMILY SSF53187 7 433 3.55E-50 T 14-10-2018 MB46_15760 45a40be6a22bae63d54142c2084b612e 335 Hamap MF_01962 Adenine deaminase. 8 316 74.958 T 14-10-2018 IPR028892 Adenine deaminase type 2 GO:0000034|GO:0006146 KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 MB46_15760 45a40be6a22bae63d54142c2084b612e 335 Gene3D G3DSA:3.20.20.140 4 334 2.5E-100 T 14-10-2018 MB46_15760 45a40be6a22bae63d54142c2084b612e 335 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 8 326 1.5E-109 T 14-10-2018 IPR006330 Adenosine/adenine deaminase GO:0019239 Reactome: R-HSA-74217 MB46_15760 45a40be6a22bae63d54142c2084b612e 335 SUPERFAMILY SSF51556 7 322 1.15E-75 T 14-10-2018 IPR032466 Metal-dependent hydrolase MB46_15760 45a40be6a22bae63d54142c2084b612e 335 Pfam PF00962 Adenosine/AMP deaminase 8 323 5.7E-74 T 14-10-2018 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Reactome: R-HSA-74217 MB46_15760 45a40be6a22bae63d54142c2084b612e 335 ProSitePatterns PS00485 Adenosine and AMP deaminase signature. 271 277 - T 14-10-2018 IPR006650 Adenosine/AMP deaminase active site GO:0009168|GO:0019239 Reactome: R-HSA-74217 MB46_13675 6b3af0fe8f966b75454942b1472f355f 272 ProSitePatterns PS00091 Thymidylate synthase active site. 129 157 - T 14-10-2018 IPR020940 Thymidylate synthase, active site GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MB46_13675 6b3af0fe8f966b75454942b1472f355f 272 Gene3D G3DSA:3.30.572.10 5 272 9.8E-127 T 14-10-2018 IPR036926 Thymidylate synthase/dCMP hydroxymethylase superfamily KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MB46_13675 6b3af0fe8f966b75454942b1472f355f 272 Pfam PF00303 Thymidylate synthase 6 272 3.9E-122 T 14-10-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MB46_13675 6b3af0fe8f966b75454942b1472f355f 272 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 88 272 1.3E-83 T 14-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MB46_13675 6b3af0fe8f966b75454942b1472f355f 272 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 7 87 2.6E-36 T 14-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MB46_13675 6b3af0fe8f966b75454942b1472f355f 272 Hamap MF_00008 Thymidylate synthase [thyA]. 4 272 39.107 T 14-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MB46_13675 6b3af0fe8f966b75454942b1472f355f 272 PRINTS PR00108 Thymidylate synthase family signature 144 159 3.8E-46 T 14-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MB46_13675 6b3af0fe8f966b75454942b1472f355f 272 PRINTS PR00108 Thymidylate synthase family signature 205 222 3.8E-46 T 14-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MB46_13675 6b3af0fe8f966b75454942b1472f355f 272 PRINTS PR00108 Thymidylate synthase family signature 118 137 3.8E-46 T 14-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MB46_13675 6b3af0fe8f966b75454942b1472f355f 272 PRINTS PR00108 Thymidylate synthase family signature 167 193 3.8E-46 T 14-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MB46_13675 6b3af0fe8f966b75454942b1472f355f 272 PRINTS PR00108 Thymidylate synthase family signature 45 66 3.8E-46 T 14-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MB46_13675 6b3af0fe8f966b75454942b1472f355f 272 SUPERFAMILY SSF55831 6 272 2.09E-123 T 14-10-2018 IPR036926 Thymidylate synthase/dCMP hydroxymethylase superfamily KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MB46_15810 17c24c6f184aa021c507d6d88143f744 406 Gene3D G3DSA:3.20.20.60 283 398 1.2E-6 T 14-10-2018 MB46_15810 17c24c6f184aa021c507d6d88143f744 406 SUPERFAMILY SSF51621 37 336 6.59E-22 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 MB46_15810 17c24c6f184aa021c507d6d88143f744 406 Pfam PF15617 C-C_Bond_Lyase of the TIM-Barrel fold 31 390 3.4E-115 T 14-10-2018 IPR039480 C-C bond lyase-like MB46_15810 17c24c6f184aa021c507d6d88143f744 406 Gene3D G3DSA:3.20.20.60 38 247 3.3E-9 T 14-10-2018 MB46_08455 c52018ab4ab0d16dc1dedd95ad2b79a7 85 Gene3D G3DSA:3.90.940.10 8 85 2.9E-18 T 14-10-2018 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 MB46_08455 c52018ab4ab0d16dc1dedd95ad2b79a7 85 SUPERFAMILY SSF63562 8 83 4.19E-23 T 14-10-2018 IPR036161 RPB6/omega subunit-like superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 MB46_08455 c52018ab4ab0d16dc1dedd95ad2b79a7 85 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 8 80 12.771 T 14-10-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MB46_08455 c52018ab4ab0d16dc1dedd95ad2b79a7 85 Pfam PF01192 RNA polymerase Rpb6 16 77 1.0E-10 T 14-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 MB46_08455 c52018ab4ab0d16dc1dedd95ad2b79a7 85 SMART SM01409 15 79 6.7E-10 T 14-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 MB46_08455 c52018ab4ab0d16dc1dedd95ad2b79a7 85 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 9 77 6.4E-18 T 14-10-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MB46_14880 b22a5e7a0c827a259230e19fa2939669 250 SUPERFAMILY SSF52317 20 243 6.64E-63 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like MB46_14880 b22a5e7a0c827a259230e19fa2939669 250 SMART SM01211 21 246 2.9E-111 T 14-10-2018 MB46_14880 b22a5e7a0c827a259230e19fa2939669 250 Gene3D G3DSA:3.40.50.880 22 246 1.6E-55 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like MB46_14880 b22a5e7a0c827a259230e19fa2939669 250 PIRSF PIRSF001586 20 248 7.2E-78 T 14-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 MB46_14880 b22a5e7a0c827a259230e19fa2939669 250 TIGRFAM TIGR01737 FGAM_synth_I: phosphoribosylformylglycinamidine synthase I 23 244 1.1E-73 T 14-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 MB46_14880 b22a5e7a0c827a259230e19fa2939669 250 Hamap MF_00421 Phosphoribosylformylglycinamidine synthase subunit PurQ [purQ]. 22 244 36.468 T 14-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 MB46_14880 b22a5e7a0c827a259230e19fa2939669 250 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 23 228 3.4E-32 T 14-10-2018 MB46_03805 cdd59c3e1229655f67a469b30f1a49dc 89 Pfam PF00312 Ribosomal protein S15 8 88 3.4E-36 T 14-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MB46_03805 cdd59c3e1229655f67a469b30f1a49dc 89 SMART SM01387 8 88 2.2E-51 T 14-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MB46_03805 cdd59c3e1229655f67a469b30f1a49dc 89 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 7 89 3.4E-37 T 14-10-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_03805 cdd59c3e1229655f67a469b30f1a49dc 89 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 11 88 3.0E-21 T 14-10-2018 MB46_03805 cdd59c3e1229655f67a469b30f1a49dc 89 SUPERFAMILY SSF47060 3 89 1.35E-34 T 14-10-2018 IPR009068 S15/NS1, RNA-binding MB46_03805 cdd59c3e1229655f67a469b30f1a49dc 89 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 3 89 21.952 T 14-10-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_03805 cdd59c3e1229655f67a469b30f1a49dc 89 Gene3D G3DSA:1.10.287.10 1 89 3.8E-34 T 14-10-2018 MB46_03805 cdd59c3e1229655f67a469b30f1a49dc 89 ProSitePatterns PS00362 Ribosomal protein S15 signature. 39 69 - T 14-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MB46_14645 0b949eb551f8efeb251b2fd56ef9eed4 208 SUPERFAMILY SSF46689 12 82 1.15E-14 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MB46_14645 0b949eb551f8efeb251b2fd56ef9eed4 208 Gene3D G3DSA:1.10.357.10 10 203 8.9E-26 T 14-10-2018 MB46_14645 0b949eb551f8efeb251b2fd56ef9eed4 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 2.4E-5 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MB46_14645 0b949eb551f8efeb251b2fd56ef9eed4 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 2.4E-5 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MB46_14645 0b949eb551f8efeb251b2fd56ef9eed4 208 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 65 3.7E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MB46_00685 1c74bfb0c005d0f78c86f1f466e253c1 481 Gene3D G3DSA:1.20.1250.20 197 456 1.2E-15 T 14-10-2018 MB46_00685 1c74bfb0c005d0f78c86f1f466e253c1 481 Gene3D G3DSA:1.20.1250.20 8 196 1.1E-33 T 14-10-2018 MB46_00685 1c74bfb0c005d0f78c86f1f466e253c1 481 SUPERFAMILY SSF103473 11 462 6.28E-52 T 14-10-2018 IPR036259 MFS transporter superfamily MB46_00685 1c74bfb0c005d0f78c86f1f466e253c1 481 Pfam PF07690 Major Facilitator Superfamily 20 410 3.7E-36 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MB46_04715 9f2844a3bf3e31110eb4ba2ed1dea58d 567 SUPERFAMILY SSF81442 26 538 3.14E-176 T 14-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MB46_04715 9f2844a3bf3e31110eb4ba2ed1dea58d 567 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 30 535 3.8E-211 T 14-10-2018 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005886|GO:0015990|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 MB46_04715 9f2844a3bf3e31110eb4ba2ed1dea58d 567 PRINTS PR01165 Cytochrome c oxidase subunit I signature 304 319 5.8E-100 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MB46_04715 9f2844a3bf3e31110eb4ba2ed1dea58d 567 PRINTS PR01165 Cytochrome c oxidase subunit I signature 179 197 5.8E-100 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MB46_04715 9f2844a3bf3e31110eb4ba2ed1dea58d 567 PRINTS PR01165 Cytochrome c oxidase subunit I signature 237 258 5.8E-100 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MB46_04715 9f2844a3bf3e31110eb4ba2ed1dea58d 567 PRINTS PR01165 Cytochrome c oxidase subunit I signature 104 128 5.8E-100 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MB46_04715 9f2844a3bf3e31110eb4ba2ed1dea58d 567 PRINTS PR01165 Cytochrome c oxidase subunit I signature 147 159 5.8E-100 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MB46_04715 9f2844a3bf3e31110eb4ba2ed1dea58d 567 PRINTS PR01165 Cytochrome c oxidase subunit I signature 29 54 5.8E-100 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MB46_04715 9f2844a3bf3e31110eb4ba2ed1dea58d 567 PRINTS PR01165 Cytochrome c oxidase subunit I signature 258 279 5.8E-100 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MB46_04715 9f2844a3bf3e31110eb4ba2ed1dea58d 567 PRINTS PR01165 Cytochrome c oxidase subunit I signature 361 379 5.8E-100 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MB46_04715 9f2844a3bf3e31110eb4ba2ed1dea58d 567 PRINTS PR01165 Cytochrome c oxidase subunit I signature 208 227 5.8E-100 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MB46_04715 9f2844a3bf3e31110eb4ba2ed1dea58d 567 PRINTS PR01165 Cytochrome c oxidase subunit I signature 326 347 5.8E-100 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MB46_04715 9f2844a3bf3e31110eb4ba2ed1dea58d 567 PRINTS PR01165 Cytochrome c oxidase subunit I signature 439 460 5.8E-100 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MB46_04715 9f2844a3bf3e31110eb4ba2ed1dea58d 567 PRINTS PR01165 Cytochrome c oxidase subunit I signature 389 408 5.8E-100 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MB46_04715 9f2844a3bf3e31110eb4ba2ed1dea58d 567 PRINTS PR01165 Cytochrome c oxidase subunit I signature 77 100 5.8E-100 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MB46_04715 9f2844a3bf3e31110eb4ba2ed1dea58d 567 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 39 483 7.0E-150 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MB46_04715 9f2844a3bf3e31110eb4ba2ed1dea58d 567 Gene3D G3DSA:1.20.210.10 18 544 3.5E-205 T 14-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MB46_04715 9f2844a3bf3e31110eb4ba2ed1dea58d 567 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 260 314 - T 14-10-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MB46_06270 935734d73701cc7b561dbc9e8cf14ab6 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 11 27 4.2E-11 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 MB46_06270 935734d73701cc7b561dbc9e8cf14ab6 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 27 38 4.2E-11 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 MB46_06270 935734d73701cc7b561dbc9e8cf14ab6 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 38 57 4.2E-11 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 MB46_06270 935734d73701cc7b561dbc9e8cf14ab6 158 SUPERFAMILY SSF54909 73 153 4.96E-15 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel MB46_06270 935734d73701cc7b561dbc9e8cf14ab6 158 SUPERFAMILY SSF46785 11 70 1.22E-13 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_06270 935734d73701cc7b561dbc9e8cf14ab6 158 SMART SM00344 11 120 1.3E-32 T 14-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 MB46_06270 935734d73701cc7b561dbc9e8cf14ab6 158 Pfam PF13412 Winged helix-turn-helix DNA-binding 11 58 1.6E-14 T 14-10-2018 MB46_06270 935734d73701cc7b561dbc9e8cf14ab6 158 Gene3D G3DSA:1.10.10.10 14 63 3.1E-18 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_06270 935734d73701cc7b561dbc9e8cf14ab6 158 Pfam PF01037 Lrp/AsnC ligand binding domain 77 150 4.9E-18 T 14-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain MB46_06270 935734d73701cc7b561dbc9e8cf14ab6 158 Gene3D G3DSA:3.30.70.920 64 147 1.1E-23 T 14-10-2018 MB46_09595 5580183dd8422c99bc8e5a501e47ab0f 294 ProSitePatterns PS00934 Glyoxalase I signature 1. 177 198 - T 14-10-2018 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 MB46_09595 5580183dd8422c99bc8e5a501e47ab0f 294 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 175 268 6.4E-9 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MB46_09595 5580183dd8422c99bc8e5a501e47ab0f 294 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 15 127 1.1E-4 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MB46_09595 5580183dd8422c99bc8e5a501e47ab0f 294 Gene3D G3DSA:3.10.180.10 12 137 6.9E-20 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MB46_09595 5580183dd8422c99bc8e5a501e47ab0f 294 Gene3D G3DSA:3.10.180.10 173 294 4.8E-24 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MB46_09595 5580183dd8422c99bc8e5a501e47ab0f 294 SUPERFAMILY SSF54593 14 274 1.91E-29 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MB46_13965 40edc405bd31d7251b584a96d919d635 299 Gene3D G3DSA:3.40.50.1360 39 293 6.3E-47 T 14-10-2018 MB46_13965 40edc405bd31d7251b584a96d919d635 299 SUPERFAMILY SSF88659 1 33 1.66E-5 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like MB46_13965 40edc405bd31d7251b584a96d919d635 299 SUPERFAMILY SSF100950 50 292 5.27E-39 T 14-10-2018 IPR037171 NagB/RpiA transferase-like MB46_13965 40edc405bd31d7251b584a96d919d635 299 Pfam PF04198 Putative sugar-binding domain 48 291 3.6E-35 T 14-10-2018 IPR007324 Sugar-binding domain, putative GO:0030246 MB46_13965 40edc405bd31d7251b584a96d919d635 299 Gene3D G3DSA:1.10.10.60 1 38 1.4E-15 T 14-10-2018 MB46_12145 c2e60e7e835b51f32ee339378b851255 230 Gene3D G3DSA:1.10.357.10 1 228 2.2E-79 T 14-10-2018 MB46_12145 c2e60e7e835b51f32ee339378b851255 230 SUPERFAMILY SSF46689 5 80 1.08E-13 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MB46_12145 c2e60e7e835b51f32ee339378b851255 230 SUPERFAMILY SSF48498 90 223 8.0E-26 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily MB46_12145 c2e60e7e835b51f32ee339378b851255 230 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 60 7.6E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MB46_13955 06b250a7591b99228274edb80a1dd0ca 317 Gene3D G3DSA:1.10.340.30 128 246 9.2E-17 T 14-10-2018 MB46_13955 06b250a7591b99228274edb80a1dd0ca 317 SUPERFAMILY SSF48150 114 301 2.2E-28 T 14-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 MB46_00190 fcc95b3697327f052ec06ec9d474cf5e 360 Pfam PF01594 AI-2E family transporter 27 346 1.5E-54 T 14-10-2018 IPR002549 Transmembrane protein TqsA-like MB46_16075 5a3a3043a10d0ca8835faab73efb7bb8 273 Gene3D G3DSA:3.40.50.300 8 272 6.7E-72 T 14-10-2018 MB46_16075 5a3a3043a10d0ca8835faab73efb7bb8 273 SUPERFAMILY SSF52540 11 270 5.48E-59 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_16075 5a3a3043a10d0ca8835faab73efb7bb8 273 Pfam PF13614 AAA domain 11 194 2.9E-54 T 14-10-2018 IPR025669 AAA domain MB46_12760 325fff27263c3ec71a3cf510bd2214c8 314 SMART SM00382 42 228 2.5E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_12760 325fff27263c3ec71a3cf510bd2214c8 314 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_12760 325fff27263c3ec71a3cf510bd2214c8 314 SUPERFAMILY SSF52540 17 232 3.26E-50 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_12760 325fff27263c3ec71a3cf510bd2214c8 314 Gene3D G3DSA:3.40.50.300 8 244 1.4E-53 T 14-10-2018 MB46_12760 325fff27263c3ec71a3cf510bd2214c8 314 Pfam PF00005 ABC transporter 33 172 1.8E-24 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_10830 1500b47d8928df6ec51adc78161a6448 143 Pfam PF10739 Protein of unknown function (DUF2550) 16 136 9.4E-33 T 14-10-2018 IPR019675 Protein of unknown function DUF2550 MB46_10895 3b91eac1d3a62b5ead355c516de96fa5 299 Pfam PF00535 Glycosyl transferase family 2 10 130 2.4E-11 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MB46_10895 3b91eac1d3a62b5ead355c516de96fa5 299 SUPERFAMILY SSF53448 3 244 6.83E-30 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MB46_10895 3b91eac1d3a62b5ead355c516de96fa5 299 Gene3D G3DSA:3.90.550.10 1 214 2.6E-19 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MB46_00450 932401a98e4c0440897c3f68bc45df33 519 Pfam PF08244 Glycosyl hydrolases family 32 C terminal 377 513 1.3E-20 T 14-10-2018 IPR013189 Glycosyl hydrolase family 32, C-terminal MB46_00450 932401a98e4c0440897c3f68bc45df33 519 SMART SM00640 42 479 1.8E-99 T 14-10-2018 IPR001362 Glycoside hydrolase, family 32 GO:0004553|GO:0005975 MB46_00450 932401a98e4c0440897c3f68bc45df33 519 SUPERFAMILY SSF75005 37 351 7.53E-57 T 14-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily MB46_00450 932401a98e4c0440897c3f68bc45df33 519 Gene3D G3DSA:2.60.120.560 365 519 6.4E-46 T 14-10-2018 MB46_00450 932401a98e4c0440897c3f68bc45df33 519 SUPERFAMILY SSF49899 361 516 2.61E-28 T 14-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily MB46_00450 932401a98e4c0440897c3f68bc45df33 519 Gene3D G3DSA:2.115.10.20 39 364 4.4E-94 T 14-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily MB46_00450 932401a98e4c0440897c3f68bc45df33 519 Pfam PF00251 Glycosyl hydrolases family 32 N-terminal domain 42 358 3.4E-58 T 14-10-2018 IPR013148 Glycosyl hydrolase family 32, N-terminal MB46_06935 906560e9483a9df8e2ebed5804bbc1ac 305 Gene3D G3DSA:1.10.10.10 1 87 5.5E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_06935 906560e9483a9df8e2ebed5804bbc1ac 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 5.7E-18 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MB46_06935 906560e9483a9df8e2ebed5804bbc1ac 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.4E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MB46_06935 906560e9483a9df8e2ebed5804bbc1ac 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.4E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MB46_06935 906560e9483a9df8e2ebed5804bbc1ac 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.4E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MB46_06935 906560e9483a9df8e2ebed5804bbc1ac 305 SUPERFAMILY SSF46785 1 79 1.2E-17 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_06935 906560e9483a9df8e2ebed5804bbc1ac 305 SUPERFAMILY SSF53850 89 288 4.44E-24 T 14-10-2018 MB46_06935 906560e9483a9df8e2ebed5804bbc1ac 305 Gene3D G3DSA:3.40.190.10 93 286 2.7E-40 T 14-10-2018 MB46_06935 906560e9483a9df8e2ebed5804bbc1ac 305 Gene3D G3DSA:3.40.190.10 161 266 2.7E-40 T 14-10-2018 MB46_06935 906560e9483a9df8e2ebed5804bbc1ac 305 Pfam PF03466 LysR substrate binding domain 87 288 5.9E-25 T 14-10-2018 IPR005119 LysR, substrate-binding MB46_18205 412b2efe785e53cf4490801334c76864 333 Pfam PF07582 AP endonuclease family 2 C terminus 274 328 3.5E-22 T 14-10-2018 IPR011418 AP endonuclease, family 2, C-terminal MB46_18205 412b2efe785e53cf4490801334c76864 333 SUPERFAMILY SSF51658 8 315 2.09E-57 T 14-10-2018 IPR036237 Xylose isomerase-like superfamily MB46_18205 412b2efe785e53cf4490801334c76864 333 Gene3D G3DSA:3.20.20.150 2 322 1.6E-99 T 14-10-2018 MB46_18205 412b2efe785e53cf4490801334c76864 333 Pfam PF01261 Xylose isomerase-like TIM barrel 22 272 4.1E-38 T 14-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain MB46_07670 1a4cd75bf48f0cf1ec9b034567c8493b 256 Pfam PF00977 Histidine biosynthesis protein 6 236 1.2E-83 T 14-10-2018 IPR006062 Histidine biosynthesis GO:0000105 MB46_07670 1a4cd75bf48f0cf1ec9b034567c8493b 256 Gene3D G3DSA:3.20.20.70 1 256 2.0E-97 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MB46_07670 1a4cd75bf48f0cf1ec9b034567c8493b 256 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 2 256 44.728 T 14-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 MB46_07670 1a4cd75bf48f0cf1ec9b034567c8493b 256 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 3 256 1.6E-105 T 14-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 MB46_07670 1a4cd75bf48f0cf1ec9b034567c8493b 256 SUPERFAMILY SSF51366 4 256 2.04E-76 T 14-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 MB46_14555 c5b918a89e466ccabc709de68d2bb37b 804 Gene3D G3DSA:2.70.98.50 33 329 3.0E-176 T 14-10-2018 MB46_14555 c5b918a89e466ccabc709de68d2bb37b 804 Pfam PF14498 Glycosyl hydrolase family 65, N-terminal domain 20 283 1.3E-44 T 14-10-2018 IPR027414 Glycosyl hydrolase family 95, N-terminal domain KEGG: 00511+3.2.1.51|MetaCyc: PWY-6807 MB46_14555 c5b918a89e466ccabc709de68d2bb37b 804 PIRSF PIRSF007663 2 798 9.0E-205 T 14-10-2018 IPR016518 Alpha-L-fucosidase GO:0004560 KEGG: 00511+3.2.1.51|MetaCyc: PWY-6807 MB46_14555 c5b918a89e466ccabc709de68d2bb37b 804 Gene3D G3DSA:1.50.10.10 31 763 3.0E-176 T 14-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 MB46_14555 c5b918a89e466ccabc709de68d2bb37b 804 Gene3D G3DSA:2.60.40.1180 330 766 3.0E-176 T 14-10-2018 IPR013780 Glycosyl hydrolase, all-beta MB46_14555 c5b918a89e466ccabc709de68d2bb37b 804 SUPERFAMILY SSF48208 297 757 8.84E-67 T 14-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 MB46_02925 0468cf2040b0044d9ab3f09f4b18cffc 443 Pfam PF01882 Protein of unknown function DUF58 249 329 8.7E-24 T 14-10-2018 IPR002881 Domain of unknown function DUF58 MB46_00155 9c0db969e1884fde4bec450b8cd3f166 318 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 24 59 9.8E-6 T 14-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain MB46_00155 9c0db969e1884fde4bec450b8cd3f166 318 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 107 291 1.2E-18 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_00155 9c0db969e1884fde4bec450b8cd3f166 318 Gene3D G3DSA:1.10.3720.10 79 287 7.3E-15 T 14-10-2018 IPR035906 MetI-like superfamily MB46_00155 9c0db969e1884fde4bec450b8cd3f166 318 SUPERFAMILY SSF161098 87 268 1.83E-17 T 14-10-2018 IPR035906 MetI-like superfamily MB46_08385 db6b804496e6e52452463d687af2abc9 151 Gene3D G3DSA:2.60.200.20 32 146 8.6E-31 T 14-10-2018 MB46_08385 db6b804496e6e52452463d687af2abc9 151 Pfam PF16697 Inner membrane component of T3SS, cytoplasmic domain 56 140 5.2E-17 T 14-10-2018 IPR032030 YscD, cytoplasmic domain MB46_08385 db6b804496e6e52452463d687af2abc9 151 SUPERFAMILY SSF49879 19 149 3.06E-29 T 14-10-2018 IPR008984 SMAD/FHA domain superfamily GO:0005515 MB46_08385 db6b804496e6e52452463d687af2abc9 151 SMART SM00240 70 120 7.9E-12 T 14-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 MB46_05595 64a84251620c8809e9870a300e73a962 135 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 75 4.8E-14 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MB46_05595 64a84251620c8809e9870a300e73a962 135 SUPERFAMILY SSF46785 4 90 1.08E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_05595 64a84251620c8809e9870a300e73a962 135 SMART SM00345 16 75 1.2E-13 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MB46_05595 64a84251620c8809e9870a300e73a962 135 Gene3D G3DSA:1.10.10.10 8 123 8.7E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_10100 b730f43058433fa579ed4dbbb5ef0bbf 491 SUPERFAMILY SSF55961 341 482 8.24E-5 T 14-10-2018 MB46_10100 b730f43058433fa579ed4dbbb5ef0bbf 491 Pfam PF13460 NAD(P)H-binding 8 124 4.3E-16 T 14-10-2018 IPR016040 NAD(P)-binding domain MB46_10100 b730f43058433fa579ed4dbbb5ef0bbf 491 Pfam PF11066 Protein of unknown function (DUF2867) 333 479 1.7E-35 T 14-10-2018 IPR021295 Protein of unknown function DUF2867 MB46_10100 b730f43058433fa579ed4dbbb5ef0bbf 491 Gene3D G3DSA:3.40.50.720 3 281 5.0E-38 T 14-10-2018 MB46_10100 b730f43058433fa579ed4dbbb5ef0bbf 491 SUPERFAMILY SSF51735 1 274 2.2E-43 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_11120 c879676b2f696935614fce7ec786ebf3 158 SUPERFAMILY SSF52540 1 150 9.91E-22 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_11120 c879676b2f696935614fce7ec786ebf3 158 TIGRFAM TIGR01313 therm_gnt_kin: carbohydrate kinase, thermoresistant glucokinase family 1 150 2.4E-55 T 14-10-2018 IPR006001 Carbohydrate kinase, thermoresistant glucokinase GO:0005975|GO:0016301 KEGG: 00030+2.7.1.12|MetaCyc: PWY-5530 MB46_11120 c879676b2f696935614fce7ec786ebf3 158 Pfam PF01202 Shikimate kinase 4 150 1.4E-15 T 14-10-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 MB46_11120 c879676b2f696935614fce7ec786ebf3 158 Gene3D G3DSA:3.40.50.300 1 158 4.6E-59 T 14-10-2018 MB46_03075 15f7bc2f0aee68fa47220d1628504246 561 Gene3D G3DSA:3.40.190.10 103 534 1.4E-24 T 14-10-2018 MB46_03075 15f7bc2f0aee68fa47220d1628504246 561 SUPERFAMILY SSF53850 114 545 1.0E-39 T 14-10-2018 MB46_05840 b642861d60a99ffc31fc0a4a32d13a08 228 Hamap MF_01385 Urease accessory protein UreF [ureF]. 7 228 27.603 T 14-10-2018 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 MB46_05840 b642861d60a99ffc31fc0a4a32d13a08 228 Gene3D G3DSA:1.10.4190.10 5 205 4.7E-59 T 14-10-2018 IPR038277 UreF domain superfamily MB46_05840 b642861d60a99ffc31fc0a4a32d13a08 228 Pfam PF01730 UreF 39 185 3.5E-30 T 14-10-2018 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 MB46_05840 b642861d60a99ffc31fc0a4a32d13a08 228 PIRSF PIRSF009467 5 228 2.5E-67 T 14-10-2018 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 MB46_08365 325c61984095e7a5ff9837b6cb5548cd 278 Gene3D G3DSA:3.40.50.300 1 275 3.7E-45 T 14-10-2018 MB46_08365 325c61984095e7a5ff9837b6cb5548cd 278 Pfam PF13614 AAA domain 2 190 2.4E-22 T 14-10-2018 IPR025669 AAA domain MB46_08365 325c61984095e7a5ff9837b6cb5548cd 278 SUPERFAMILY SSF52540 2 267 1.57E-33 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_07395 a862a024979b46dbe028216f57d155ae 520 SUPERFAMILY SSF49401 34 147 1.62E-16 T 14-10-2018 IPR008966 Adhesion domain superfamily MB46_07395 a862a024979b46dbe028216f57d155ae 520 Gene3D G3DSA:2.60.40.1280 17 159 7.9E-19 T 14-10-2018 IPR011252 Fibrogen-binding domain 1 GO:0007155 MB46_05610 70319acea11ae25dcf45bc7803c89241 282 Pfam PF13649 Methyltransferase domain 54 150 8.3E-16 T 14-10-2018 MB46_05610 70319acea11ae25dcf45bc7803c89241 282 SUPERFAMILY SSF53335 35 243 8.05E-32 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MB46_05610 70319acea11ae25dcf45bc7803c89241 282 Gene3D G3DSA:3.40.50.150 3 250 7.3E-33 T 14-10-2018 MB46_12310 83694d1b12f7345f894ea954fb809336 310 Gene3D G3DSA:1.10.3720.10 59 293 1.2E-58 T 14-10-2018 IPR035906 MetI-like superfamily MB46_12310 83694d1b12f7345f894ea954fb809336 310 SUPERFAMILY SSF161098 70 291 6.93E-46 T 14-10-2018 IPR035906 MetI-like superfamily MB46_12310 83694d1b12f7345f894ea954fb809336 310 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 90 290 4.4E-26 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_12310 83694d1b12f7345f894ea954fb809336 310 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 69 134 3.5E-17 T 14-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 MB46_10975 1645a47dce0a9659c155998ff89635d6 459 Pfam PF00232 Glycosyl hydrolase family 1 8 454 1.7E-147 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 MB46_10975 1645a47dce0a9659c155998ff89635d6 459 Gene3D G3DSA:3.20.20.80 2 457 1.8E-164 T 14-10-2018 MB46_10975 1645a47dce0a9659c155998ff89635d6 459 TIGRFAM TIGR03356 BGL: beta-galactosidase 9 447 1.0E-169 T 14-10-2018 IPR017736 Glycoside hydrolase, family 1, beta-glucosidase GO:0008422|GO:0030245 KEGG: 00460+3.2.1.21|KEGG: 00500+3.2.1.21|KEGG: 00940+3.2.1.21|MetaCyc: PWY-3121|MetaCyc: PWY-5176|MetaCyc: PWY-6002|MetaCyc: PWY-6788|MetaCyc: PWY-7091|MetaCyc: PWY-7092|MetaCyc: PWY-7913 MB46_10975 1645a47dce0a9659c155998ff89635d6 459 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 359 367 - T 14-10-2018 IPR018120 Glycoside hydrolase family 1, active site MB46_10975 1645a47dce0a9659c155998ff89635d6 459 PRINTS PR00131 Glycosyl hydrolase family 1 signature 425 437 1.4E-19 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 MB46_10975 1645a47dce0a9659c155998ff89635d6 459 PRINTS PR00131 Glycosyl hydrolase family 1 signature 380 391 1.4E-19 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 MB46_10975 1645a47dce0a9659c155998ff89635d6 459 PRINTS PR00131 Glycosyl hydrolase family 1 signature 283 297 1.4E-19 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 MB46_10975 1645a47dce0a9659c155998ff89635d6 459 PRINTS PR00131 Glycosyl hydrolase family 1 signature 401 418 1.4E-19 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 MB46_10975 1645a47dce0a9659c155998ff89635d6 459 PRINTS PR00131 Glycosyl hydrolase family 1 signature 359 367 1.4E-19 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 MB46_10975 1645a47dce0a9659c155998ff89635d6 459 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 13 27 - T 14-10-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site MB46_10975 1645a47dce0a9659c155998ff89635d6 459 SUPERFAMILY SSF51445 9 454 4.86E-155 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily MB46_01005 406d442e07deedd9750642f2951593c5 419 SUPERFAMILY SSF53218 199 344 2.88E-25 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily MB46_01005 406d442e07deedd9750642f2951593c5 419 Gene3D G3DSA:3.90.105.10 51 196 8.9E-75 T 14-10-2018 MB46_01005 406d442e07deedd9750642f2951593c5 419 SUPERFAMILY SSF63882 31 196 9.81E-33 T 14-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MB46_01005 406d442e07deedd9750642f2951593c5 419 Pfam PF03453 MoeA N-terminal region (domain I and II) 32 185 5.2E-32 T 14-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MB46_01005 406d442e07deedd9750642f2951593c5 419 Gene3D G3DSA:2.170.190.11 73 162 8.9E-75 T 14-10-2018 MB46_01005 406d442e07deedd9750642f2951593c5 419 Pfam PF00994 Probable molybdopterin binding domain 203 339 2.3E-17 T 14-10-2018 IPR001453 MoaB/Mog domain MB46_01005 406d442e07deedd9750642f2951593c5 419 Gene3D G3DSA:3.40.980.10 197 341 8.9E-75 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily MB46_01005 406d442e07deedd9750642f2951593c5 419 SMART SM00852 201 340 1.1E-19 T 14-10-2018 IPR001453 MoaB/Mog domain MB46_01530 966c1ce0e70954209806346407d5b0b8 343 Pfam PF04587 ADP-specific Phosphofructokinase/Glucokinase conserved region 5 263 2.5E-27 T 14-10-2018 IPR007666 ADP-specific phosphofructokinase/glucokinase GO:0005975|GO:0016773 Reactome: R-HSA-70171 MB46_01530 966c1ce0e70954209806346407d5b0b8 343 Gene3D G3DSA:3.40.1190.20 89 323 5.1E-27 T 14-10-2018 IPR029056 Ribokinase-like MB46_01530 966c1ce0e70954209806346407d5b0b8 343 Gene3D G3DSA:3.30.1110.20 13 170 5.1E-27 T 14-10-2018 MB46_01530 966c1ce0e70954209806346407d5b0b8 343 SUPERFAMILY SSF53613 6 328 3.43E-25 T 14-10-2018 IPR029056 Ribokinase-like MB46_13985 161d9b3590ee5ffe8477336dbf6edde8 152 Gene3D G3DSA:3.40.1400.10 5 152 1.1E-47 T 14-10-2018 IPR036569 Sugar-phosphate isomerase, RpiB/LacA/LacB superfamily GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 MB46_13985 161d9b3590ee5ffe8477336dbf6edde8 152 TIGRFAM TIGR02133 RPI_actino: ribose 5-phosphate isomerase 5 151 3.1E-59 T 14-10-2018 IPR011860 Ribose 5-phosphate isomerase GO:0004751 MB46_13985 161d9b3590ee5ffe8477336dbf6edde8 152 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 7 151 2.6E-33 T 14-10-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 MB46_13985 161d9b3590ee5ffe8477336dbf6edde8 152 PIRSF PIRSF005384 5 152 8.0E-45 T 14-10-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 MB46_13985 161d9b3590ee5ffe8477336dbf6edde8 152 SUPERFAMILY SSF89623 2 151 1.06E-47 T 14-10-2018 IPR036569 Sugar-phosphate isomerase, RpiB/LacA/LacB superfamily GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 MB46_13985 161d9b3590ee5ffe8477336dbf6edde8 152 Pfam PF02502 Ribose/Galactose Isomerase 7 145 5.8E-45 T 14-10-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 MB46_03435 8ee774cef6f0e272224e43204cd8915b 139 Gene3D G3DSA:1.10.1660.10 78 131 1.9E-7 T 14-10-2018 MB46_03435 8ee774cef6f0e272224e43204cd8915b 139 Pfam PF12728 Helix-turn-helix domain 82 126 1.6E-8 T 14-10-2018 MB46_03435 8ee774cef6f0e272224e43204cd8915b 139 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 82 125 8.6E-8 T 14-10-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 MB46_10180 5094d6702fe27735759438e52f3971fc 454 PIRSF PIRSF001092 11 420 9.0E-106 T 14-10-2018 IPR016286 Alpha-L-fucosidase, metazoa-type GO:0004560|GO:0006004 KEGG: 00511+3.2.1.51|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 MB46_10180 5094d6702fe27735759438e52f3971fc 454 Pfam PF01120 Alpha-L-fucosidase 18 359 5.6E-93 T 14-10-2018 IPR000933 Glycoside hydrolase, family 29 GO:0004560|GO:0005975 KEGG: 00511+3.2.1.51|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 MB46_10180 5094d6702fe27735759438e52f3971fc 454 SMART SM00812 11 405 5.6E-140 T 14-10-2018 IPR000933 Glycoside hydrolase, family 29 GO:0004560|GO:0005975 KEGG: 00511+3.2.1.51|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 MB46_10180 5094d6702fe27735759438e52f3971fc 454 Gene3D G3DSA:3.20.20.80 8 362 2.0E-123 T 14-10-2018 MB46_10180 5094d6702fe27735759438e52f3971fc 454 PRINTS PR00741 Glycosyl hydrolase family 29 signature 215 231 5.9E-30 T 14-10-2018 IPR016286 Alpha-L-fucosidase, metazoa-type GO:0004560|GO:0006004 KEGG: 00511+3.2.1.51|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 MB46_10180 5094d6702fe27735759438e52f3971fc 454 PRINTS PR00741 Glycosyl hydrolase family 29 signature 85 100 5.9E-30 T 14-10-2018 IPR016286 Alpha-L-fucosidase, metazoa-type GO:0004560|GO:0006004 KEGG: 00511+3.2.1.51|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 MB46_10180 5094d6702fe27735759438e52f3971fc 454 PRINTS PR00741 Glycosyl hydrolase family 29 signature 124 140 5.9E-30 T 14-10-2018 IPR016286 Alpha-L-fucosidase, metazoa-type GO:0004560|GO:0006004 KEGG: 00511+3.2.1.51|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 MB46_10180 5094d6702fe27735759438e52f3971fc 454 PRINTS PR00741 Glycosyl hydrolase family 29 signature 345 367 5.9E-30 T 14-10-2018 IPR016286 Alpha-L-fucosidase, metazoa-type GO:0004560|GO:0006004 KEGG: 00511+3.2.1.51|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 MB46_10180 5094d6702fe27735759438e52f3971fc 454 PRINTS PR00741 Glycosyl hydrolase family 29 signature 243 264 5.9E-30 T 14-10-2018 IPR016286 Alpha-L-fucosidase, metazoa-type GO:0004560|GO:0006004 KEGG: 00511+3.2.1.51|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 MB46_10180 5094d6702fe27735759438e52f3971fc 454 PRINTS PR00741 Glycosyl hydrolase family 29 signature 312 333 5.9E-30 T 14-10-2018 IPR016286 Alpha-L-fucosidase, metazoa-type GO:0004560|GO:0006004 KEGG: 00511+3.2.1.51|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 MB46_10180 5094d6702fe27735759438e52f3971fc 454 SUPERFAMILY SSF51445 15 362 5.69E-103 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily MB46_14150 bc5daaa78a8d7baf27751caba8aa02de 476 Gene3D G3DSA:3.40.309.10 252 440 2.7E-158 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 MB46_14150 bc5daaa78a8d7baf27751caba8aa02de 476 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 275 286 - T 14-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 MB46_14150 bc5daaa78a8d7baf27751caba8aa02de 476 Gene3D G3DSA:3.40.605.10 9 468 2.7E-158 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 MB46_14150 bc5daaa78a8d7baf27751caba8aa02de 476 Pfam PF00171 Aldehyde dehydrogenase family 20 470 5.3E-151 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 MB46_14150 bc5daaa78a8d7baf27751caba8aa02de 476 SUPERFAMILY SSF53720 3 473 1.96E-149 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 MB46_14150 bc5daaa78a8d7baf27751caba8aa02de 476 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 247 254 - T 14-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 MB46_09040 333250039941deecfea2fadfc19ee55d 208 Gene3D G3DSA:3.40.30.10 3 208 6.1E-75 T 14-10-2018 MB46_09040 333250039941deecfea2fadfc19ee55d 208 SUPERFAMILY SSF52833 11 168 1.64E-18 T 14-10-2018 IPR036249 Thioredoxin-like superfamily MB46_09040 333250039941deecfea2fadfc19ee55d 208 Pfam PF01323 DSBA-like thioredoxin domain 13 166 7.7E-7 T 14-10-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590|Reactome: R-HSA-9033241 MB46_07120 c8c737a903922ea6cded1a2c5b9db7fc 437 Gene3D G3DSA:1.20.272.10 230 334 1.6E-46 T 14-10-2018 MB46_07120 c8c737a903922ea6cded1a2c5b9db7fc 437 Pfam PF12002 MgsA AAA+ ATPase C terminal 257 422 3.2E-66 T 14-10-2018 IPR021886 MgsA AAA+ ATPase C-terminal MB46_07120 c8c737a903922ea6cded1a2c5b9db7fc 437 Gene3D G3DSA:3.40.50.300 6 165 8.0E-43 T 14-10-2018 MB46_07120 c8c737a903922ea6cded1a2c5b9db7fc 437 Gene3D G3DSA:1.10.3710.10 335 433 2.0E-28 T 14-10-2018 MB46_07120 c8c737a903922ea6cded1a2c5b9db7fc 437 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 54 162 9.5E-15 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MB46_07120 c8c737a903922ea6cded1a2c5b9db7fc 437 SUPERFAMILY SSF48019 242 426 1.56E-72 T 14-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 MB46_07120 c8c737a903922ea6cded1a2c5b9db7fc 437 SMART SM00382 50 166 3.8E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_07120 c8c737a903922ea6cded1a2c5b9db7fc 437 SUPERFAMILY SSF52540 11 218 3.28E-42 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_07120 c8c737a903922ea6cded1a2c5b9db7fc 437 Pfam PF16193 AAA C-terminal domain 185 256 9.3E-20 T 14-10-2018 IPR032423 AAA C-terminal domain MB46_18000 7a50f7bb2b308d62e3402a52e2b650c4 189 Pfam PF01872 RibD C-terminal domain 6 175 5.0E-11 T 14-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 MB46_18000 7a50f7bb2b308d62e3402a52e2b650c4 189 SUPERFAMILY SSF53597 2 186 1.83E-24 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 MB46_18000 7a50f7bb2b308d62e3402a52e2b650c4 189 Gene3D G3DSA:3.40.430.10 2 182 1.7E-33 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 MB46_08830 4371f4022ca7db05c25306082cd0bb75 198 SUPERFAMILY SSF51161 18 196 2.77E-49 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily MB46_08830 4371f4022ca7db05c25306082cd0bb75 198 Pfam PF12464 Maltose acetyltransferase 20 71 6.1E-8 T 14-10-2018 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 MB46_08830 4371f4022ca7db05c25306082cd0bb75 198 SMART SM01266 18 72 2.1E-9 T 14-10-2018 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 MB46_08830 4371f4022ca7db05c25306082cd0bb75 198 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 144 178 6.1E-10 T 14-10-2018 IPR001451 Hexapeptide repeat MB46_08830 4371f4022ca7db05c25306082cd0bb75 198 Gene3D G3DSA:2.160.10.10 15 198 3.1E-61 T 14-10-2018 MB46_08830 4371f4022ca7db05c25306082cd0bb75 198 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 152 180 - T 14-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 MB46_11955 df081412ca8e153d728dfc1be8ac8ff7 472 TIGRFAM TIGR03624 TIGR03624: putative hydrolase 71 421 5.4E-109 T 14-10-2018 IPR018766 Zinicin-like metallopeptidase type 2 MB46_11955 df081412ca8e153d728dfc1be8ac8ff7 472 Pfam PF10103 Zincin-like metallopeptidase 71 418 4.5E-114 T 14-10-2018 IPR018766 Zinicin-like metallopeptidase type 2 MB46_11955 df081412ca8e153d728dfc1be8ac8ff7 472 Gene3D G3DSA:1.20.150.30 71 206 4.8E-9 T 14-10-2018 MB46_11955 df081412ca8e153d728dfc1be8ac8ff7 472 SUPERFAMILY SSF55486 70 421 1.61E-105 T 14-10-2018 MB46_17415 7c1ecf30e33b6a66519a868658fe9a46 115 Pfam PF14029 Protein of unknown function (DUF4244) 67 114 1.4E-21 T 14-10-2018 IPR025338 Protein of unknown function DUF4244 MB46_05160 74894a78bf32b82b95d959fd24b4b11b 301 SUPERFAMILY SSF55486 142 288 4.89E-7 T 14-10-2018 MB46_05160 74894a78bf32b82b95d959fd24b4b11b 301 Pfam PF04228 Putative neutral zinc metallopeptidase 12 296 3.1E-75 T 14-10-2018 IPR007343 Uncharacterised protein family, zinc metallopeptidase putative MB46_06860 21e96fb741a2443ae846b4e7443ce0d5 289 Pfam PF07848 PaaX-like protein 17 82 2.9E-8 T 14-10-2018 IPR012906 PaaX-like, N-terminal MB46_06860 21e96fb741a2443ae846b4e7443ce0d5 289 PIRSF PIRSF020623 2 288 5.8E-67 T 14-10-2018 IPR011965 Phenylacetic acid degradation operon negative regulatory protein PaaX GO:0006351 MB46_06860 21e96fb741a2443ae846b4e7443ce0d5 289 Pfam PF08223 PaaX-like protein C-terminal domain 179 271 1.6E-18 T 14-10-2018 IPR013225 PaaX-like, C-terminal MB46_06860 21e96fb741a2443ae846b4e7443ce0d5 289 Gene3D G3DSA:1.10.10.10 14 95 5.6E-15 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_03615 301f09a44e1bba8f588cacda4f59abe3 159 SUPERFAMILY SSF54637 7 157 2.56E-43 T 14-10-2018 IPR029069 HotDog domain superfamily MB46_03615 301f09a44e1bba8f588cacda4f59abe3 159 Pfam PF01575 MaoC like domain 18 133 1.4E-22 T 14-10-2018 IPR002539 MaoC-like dehydratase domain MB46_03615 301f09a44e1bba8f588cacda4f59abe3 159 Gene3D G3DSA:3.10.129.10 3 157 2.6E-45 T 14-10-2018 MB46_04540 8bb708aed95fff53243c0ef112476fbe 571 SUPERFAMILY SSF51905 10 361 5.18E-24 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_04540 8bb708aed95fff53243c0ef112476fbe 571 Gene3D G3DSA:3.50.50.60 12 408 4.9E-102 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_04540 8bb708aed95fff53243c0ef112476fbe 571 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 423 546 4.1E-17 T 14-10-2018 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 MB46_04540 8bb708aed95fff53243c0ef112476fbe 571 Gene3D G3DSA:1.10.8.870 441 567 2.3E-16 T 14-10-2018 IPR038299 Alpha-glycerophosphate oxidase, C-terminal domain superfamily KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 MB46_04540 8bb708aed95fff53243c0ef112476fbe 571 Gene3D G3DSA:3.30.9.10 88 360 4.9E-102 T 14-10-2018 MB46_04540 8bb708aed95fff53243c0ef112476fbe 571 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 84 96 1.9E-19 T 14-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 MB46_04540 8bb708aed95fff53243c0ef112476fbe 571 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 353 359 1.9E-19 T 14-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 MB46_04540 8bb708aed95fff53243c0ef112476fbe 571 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 23 33 1.9E-19 T 14-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 MB46_04540 8bb708aed95fff53243c0ef112476fbe 571 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 39 51 1.9E-19 T 14-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 MB46_04540 8bb708aed95fff53243c0ef112476fbe 571 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 10 22 1.9E-19 T 14-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 MB46_04540 8bb708aed95fff53243c0ef112476fbe 571 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 390 402 1.9E-19 T 14-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 MB46_04540 8bb708aed95fff53243c0ef112476fbe 571 Pfam PF01266 FAD dependent oxidoreductase 11 362 1.2E-42 T 14-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 MB46_05535 3cb4edf8337d6f21b971aaa56631d7c6 163 Gene3D G3DSA:1.10.10.10 6 152 1.0E-30 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_05535 3cb4edf8337d6f21b971aaa56631d7c6 163 Pfam PF01047 MarR family 39 98 9.2E-10 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MB46_05535 3cb4edf8337d6f21b971aaa56631d7c6 163 SMART SM00347 32 135 7.3E-10 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MB46_05535 3cb4edf8337d6f21b971aaa56631d7c6 163 SUPERFAMILY SSF46785 8 150 2.7E-23 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_18890 2d7c9a75d3437ceb0c7cc14fa6bc3521 435 SUPERFAMILY SSF53850 32 432 5.64E-51 T 14-10-2018 MB46_18890 2d7c9a75d3437ceb0c7cc14fa6bc3521 435 Pfam PF13416 Bacterial extracellular solute-binding protein 61 363 1.7E-37 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein MB46_18890 2d7c9a75d3437ceb0c7cc14fa6bc3521 435 Gene3D G3DSA:3.40.190.10 32 432 1.7E-58 T 14-10-2018 MB46_13380 bc576eac06dd1962a9fd9460adfa8241 120 SUPERFAMILY SSF50104 3 99 2.17E-26 T 14-10-2018 IPR008991 Translation protein SH3-like domain superfamily MB46_13380 bc576eac06dd1962a9fd9460adfa8241 120 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 45 118 3.2E-22 T 14-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_13380 bc576eac06dd1962a9fd9460adfa8241 120 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 1 118 5.0E-30 T 14-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_13380 bc576eac06dd1962a9fd9460adfa8241 120 Gene3D G3DSA:2.30.30.30 1 118 6.3E-33 T 14-10-2018 IPR014722 Ribosomal protein L2, domain 2 MB46_13380 bc576eac06dd1962a9fd9460adfa8241 120 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 2 113 21.772 T 14-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_11965 e5c1e1bf9f30cc4d08fa7dd2beef0675 387 SUPERFAMILY SSF69572 144 321 6.67E-17 T 14-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 MB46_11965 e5c1e1bf9f30cc4d08fa7dd2beef0675 387 Pfam PF00899 ThiF family 147 371 7.1E-12 T 14-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 MB46_11965 e5c1e1bf9f30cc4d08fa7dd2beef0675 387 TIGRFAM TIGR03882 cyclo_dehyd_2: bacteriocin biosynthesis cyclodehydratase domain 258 369 6.0E-10 T 14-10-2018 IPR022291 Bacteriocin biosynthesis, cyclodehydratase domain MB46_11965 e5c1e1bf9f30cc4d08fa7dd2beef0675 387 Gene3D G3DSA:3.40.50.720 132 372 9.4E-22 T 14-10-2018 MB46_15735 1235044c696a6f226f29be2a293dbfd9 204 Gene3D G3DSA:3.40.50.10420 27 203 1.1E-56 T 14-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily MB46_15735 1235044c696a6f226f29be2a293dbfd9 204 Pfam PF02589 LUD domain 34 203 8.0E-22 T 14-10-2018 IPR003741 LUD domain MB46_15735 1235044c696a6f226f29be2a293dbfd9 204 SUPERFAMILY SSF100950 28 203 8.37E-36 T 14-10-2018 IPR037171 NagB/RpiA transferase-like MB46_09550 1f8d20939f9b87eda2b8c30c767bcecf 222 Pfam PF01351 Ribonuclease HII 23 220 1.9E-29 T 14-10-2018 IPR024567 Ribonuclease HII/HIII domain MB46_09550 1f8d20939f9b87eda2b8c30c767bcecf 222 SUPERFAMILY SSF53098 11 220 1.08E-51 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily MB46_09550 1f8d20939f9b87eda2b8c30c767bcecf 222 Gene3D G3DSA:3.30.420.10 6 222 6.3E-62 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 MB46_13190 c933c9079106d853b60b2d09a3d360e3 309 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 102 297 3.7E-15 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_13190 c933c9079106d853b60b2d09a3d360e3 309 Gene3D G3DSA:1.10.3720.10 66 307 1.5E-61 T 14-10-2018 IPR035906 MetI-like superfamily MB46_13190 c933c9079106d853b60b2d09a3d360e3 309 SUPERFAMILY SSF161098 71 296 3.01E-53 T 14-10-2018 IPR035906 MetI-like superfamily MB46_17575 e2923defef86b0627bda71c6286966cc 699 SUPERFAMILY SSF48208 290 691 1.87E-34 T 14-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 MB46_11840 2e26b7de29d5c0022e6b8180465286ed 269 Pfam PF13531 Bacterial extracellular solute-binding protein 49 266 3.3E-42 T 14-10-2018 MB46_11840 2e26b7de29d5c0022e6b8180465286ed 269 PIRSF PIRSF004846 1 269 7.2E-63 T 14-10-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689 MB46_11840 2e26b7de29d5c0022e6b8180465286ed 269 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 54 263 1.1E-38 T 14-10-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689 MB46_11840 2e26b7de29d5c0022e6b8180465286ed 269 SUPERFAMILY SSF53850 48 267 7.35E-53 T 14-10-2018 MB46_11840 2e26b7de29d5c0022e6b8180465286ed 269 Gene3D G3DSA:3.40.190.10 127 227 8.5E-61 T 14-10-2018 MB46_11840 2e26b7de29d5c0022e6b8180465286ed 269 Gene3D G3DSA:3.40.190.10 50 266 8.5E-61 T 14-10-2018 MB46_06535 16e252237c19247c844babfdbd7c1355 421 Pfam PF00155 Aminotransferase class I and II 73 407 3.1E-34 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MB46_06535 16e252237c19247c844babfdbd7c1355 421 Gene3D G3DSA:3.90.1150.10 38 411 1.0E-120 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MB46_06535 16e252237c19247c844babfdbd7c1355 421 Gene3D G3DSA:3.40.640.10 82 306 1.0E-120 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MB46_06535 16e252237c19247c844babfdbd7c1355 421 SUPERFAMILY SSF53383 34 411 7.74E-97 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MB46_02845 c7f53cb95d3ad6ef9223f360790bae61 209 Gene3D G3DSA:1.10.10.60 17 65 6.6E-16 T 14-10-2018 MB46_02845 c7f53cb95d3ad6ef9223f360790bae61 209 SUPERFAMILY SSF46689 16 89 3.64E-15 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MB46_02845 c7f53cb95d3ad6ef9223f360790bae61 209 Pfam PF00440 Bacterial regulatory proteins, tetR family 29 67 7.4E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MB46_02845 c7f53cb95d3ad6ef9223f360790bae61 209 Gene3D G3DSA:1.10.357.10 67 203 1.2E-11 T 14-10-2018 MB46_01375 00a76c36983dfe41c7154bb769264f49 336 SUPERFAMILY SSF47413 7 64 1.61E-18 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MB46_01375 00a76c36983dfe41c7154bb769264f49 336 Pfam PF13377 Periplasmic binding protein-like domain 173 330 1.5E-35 T 14-10-2018 MB46_01375 00a76c36983dfe41c7154bb769264f49 336 Gene3D G3DSA:1.10.260.40 1 63 3.3E-24 T 14-10-2018 MB46_01375 00a76c36983dfe41c7154bb769264f49 336 SUPERFAMILY SSF53822 65 333 1.45E-59 T 14-10-2018 IPR028082 Periplasmic binding protein-like I MB46_01375 00a76c36983dfe41c7154bb769264f49 336 ProSitePatterns PS00356 LacI-type HTH domain signature. 9 27 - T 14-10-2018 MB46_01375 00a76c36983dfe41c7154bb769264f49 336 SMART SM00354 6 76 2.3E-29 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MB46_01375 00a76c36983dfe41c7154bb769264f49 336 Gene3D G3DSA:3.40.50.2300 83 321 1.8E-70 T 14-10-2018 MB46_01375 00a76c36983dfe41c7154bb769264f49 336 Gene3D G3DSA:3.40.50.2300 164 324 1.8E-70 T 14-10-2018 MB46_01375 00a76c36983dfe41c7154bb769264f49 336 Pfam PF00356 Bacterial regulatory proteins, lacI family 9 53 1.6E-19 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MB46_11220 5ca3392e8815a7ba974a3a85c7d44938 145 Gene3D G3DSA:1.10.490.10 5 130 1.2E-34 T 14-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 MB46_11220 5ca3392e8815a7ba974a3a85c7d44938 145 SUPERFAMILY SSF46458 7 128 1.01E-20 T 14-10-2018 IPR009050 Globin-like superfamily MB46_05655 0b7cbf18e3533162b1027d69f60756e0 265 SUPERFAMILY SSF52540 9 236 1.2E-68 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_05655 0b7cbf18e3533162b1027d69f60756e0 265 Gene3D G3DSA:3.40.50.300 7 246 9.6E-63 T 14-10-2018 MB46_05655 0b7cbf18e3533162b1027d69f60756e0 265 Pfam PF00005 ABC transporter 29 168 1.8E-31 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_05655 0b7cbf18e3533162b1027d69f60756e0 265 SMART SM00382 38 219 6.0E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_05415 397662b9a895a4e379af0cec390e5cd2 248 Gene3D G3DSA:3.60.20.10 1 248 1.8E-58 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MB46_05415 397662b9a895a4e379af0cec390e5cd2 248 Hamap MF_00289_B Proteasome subunit alpha [prcA]. 1 242 45.143 T 14-10-2018 IPR022296 Proteasome, alpha subunit, bacterial GO:0004298|GO:0019773|GO:0051603 MB46_05415 397662b9a895a4e379af0cec390e5cd2 248 TIGRFAM TIGR03691 20S_bact_alpha: proteasome, alpha subunit 1 236 2.2E-105 T 14-10-2018 IPR022296 Proteasome, alpha subunit, bacterial GO:0004298|GO:0019773|GO:0051603 MB46_05415 397662b9a895a4e379af0cec390e5cd2 248 SUPERFAMILY SSF56235 10 235 1.78E-38 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MB46_05415 397662b9a895a4e379af0cec390e5cd2 248 Pfam PF00227 Proteasome subunit 25 191 3.8E-24 T 14-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 MB46_19005 fc6319dc4e59b93b4082d49ff73e4a17 513 SUPERFAMILY SSF53474 85 484 8.54E-21 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_19005 fc6319dc4e59b93b4082d49ff73e4a17 513 Pfam PF00561 alpha/beta hydrolase fold 105 486 1.5E-30 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MB46_05720 2b8a0111e34923bb1894334a0c5d92ca 339 SUPERFAMILY SSF51735 113 300 4.83E-43 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_05720 2b8a0111e34923bb1894334a0c5d92ca 339 Gene3D G3DSA:3.40.50.720 16 319 4.1E-89 T 14-10-2018 MB46_05720 2b8a0111e34923bb1894334a0c5d92ca 339 SUPERFAMILY SSF52283 42 141 8.72E-15 T 14-10-2018 MB46_05720 2b8a0111e34923bb1894334a0c5d92ca 339 Gene3D G3DSA:3.40.50.720 112 298 4.1E-89 T 14-10-2018 MB46_05720 2b8a0111e34923bb1894334a0c5d92ca 339 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 51 329 2.8E-9 T 14-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 MB46_05720 2b8a0111e34923bb1894334a0c5d92ca 339 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 122 299 2.1E-42 T 14-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 MB46_06355 6c80a1ac3a44163eef19a37361499b13 325 Gene3D G3DSA:1.10.3720.10 106 319 1.4E-11 T 14-10-2018 IPR035906 MetI-like superfamily MB46_06355 6c80a1ac3a44163eef19a37361499b13 325 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 134 322 2.6E-25 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_06355 6c80a1ac3a44163eef19a37361499b13 325 SUPERFAMILY SSF161098 111 306 1.31E-11 T 14-10-2018 IPR035906 MetI-like superfamily MB46_01555 894b61a03141301ec788d9df9cadcd2f 548 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 187 199 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 MB46_01555 894b61a03141301ec788d9df9cadcd2f 548 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 288 442 3.5E-28 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MB46_01555 894b61a03141301ec788d9df9cadcd2f 548 Gene3D G3DSA:1.20.140.10 289 454 7.4E-35 T 14-10-2018 MB46_01555 894b61a03141301ec788d9df9cadcd2f 548 SUPERFAMILY SSF47203 286 442 1.05E-37 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 MB46_01555 894b61a03141301ec788d9df9cadcd2f 548 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 185 278 8.1E-16 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MB46_01555 894b61a03141301ec788d9df9cadcd2f 548 Gene3D G3DSA:2.40.110.20 137 288 6.8E-52 T 14-10-2018 MB46_01555 894b61a03141301ec788d9df9cadcd2f 548 SUPERFAMILY SSF56645 82 297 3.4E-37 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 MB46_13760 2e60c61516b92b82c8bce3cf1eb62203 290 SUPERFAMILY SSF51621 22 240 2.3E-49 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 MB46_13760 2e60c61516b92b82c8bce3cf1eb62203 290 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 25 226 1.1E-25 T 14-10-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 MB46_13760 2e60c61516b92b82c8bce3cf1eb62203 290 PIRSF PIRSF015582 7 289 5.3E-60 T 14-10-2018 IPR011206 Citrate lyase beta subunit-like MB46_13760 2e60c61516b92b82c8bce3cf1eb62203 290 Gene3D G3DSA:3.20.20.60 14 287 1.1E-58 T 14-10-2018 MB46_05765 840a02f3070d0b28f78930e2debad781 279 Gene3D G3DSA:3.60.15.10 3 228 1.2E-41 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MB46_05765 840a02f3070d0b28f78930e2debad781 279 SUPERFAMILY SSF56281 4 253 3.92E-42 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MB46_05765 840a02f3070d0b28f78930e2debad781 279 SMART SM00849 19 210 2.4E-16 T 14-10-2018 IPR001279 Metallo-beta-lactamase MB46_05765 840a02f3070d0b28f78930e2debad781 279 Pfam PF00753 Metallo-beta-lactamase superfamily 21 210 6.3E-14 T 14-10-2018 IPR001279 Metallo-beta-lactamase MB46_08765 39b5648f3a15e06af1b3551ebda51558 206 SUPERFAMILY SSF56281 10 198 3.25E-45 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MB46_08765 39b5648f3a15e06af1b3551ebda51558 206 Pfam PF00753 Metallo-beta-lactamase superfamily 25 188 8.1E-22 T 14-10-2018 IPR001279 Metallo-beta-lactamase MB46_08765 39b5648f3a15e06af1b3551ebda51558 206 SMART SM00849 24 188 2.1E-34 T 14-10-2018 IPR001279 Metallo-beta-lactamase MB46_08765 39b5648f3a15e06af1b3551ebda51558 206 Gene3D G3DSA:3.60.15.10 20 204 1.3E-45 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MB46_03580 a789c6cced00ba5b3f3d0de93d9634b5 122 Pfam PF03779 SPW repeat 60 104 5.2E-12 T 14-10-2018 IPR005530 SPW repeat MB46_12930 01a348e1e91dd5240e8be10f78f9883b 204 Pfam PF13302 Acetyltransferase (GNAT) domain 16 164 8.1E-18 T 14-10-2018 IPR000182 GNAT domain MB46_12930 01a348e1e91dd5240e8be10f78f9883b 204 Gene3D G3DSA:3.40.630.30 3 197 8.6E-40 T 14-10-2018 MB46_12930 01a348e1e91dd5240e8be10f78f9883b 204 SUPERFAMILY SSF55729 8 188 5.51E-35 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase MB46_06235 e5a02643d73d8f718a35f3ddcd94cbe0 277 SMART SM00382 35 216 3.6E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_06235 e5a02643d73d8f718a35f3ddcd94cbe0 277 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_06235 e5a02643d73d8f718a35f3ddcd94cbe0 277 Pfam PF00005 ABC transporter 26 167 4.7E-26 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_06235 e5a02643d73d8f718a35f3ddcd94cbe0 277 SUPERFAMILY SSF52540 9 228 1.6E-58 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_06235 e5a02643d73d8f718a35f3ddcd94cbe0 277 Gene3D G3DSA:3.40.50.300 1 236 6.1E-63 T 14-10-2018 MB46_02825 568c2f0fbb07e35c9764e59e5134cb0b 507 Pfam PF00171 Aldehyde dehydrogenase family 28 494 7.1E-163 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 MB46_02825 568c2f0fbb07e35c9764e59e5134cb0b 507 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 262 269 - T 14-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 MB46_02825 568c2f0fbb07e35c9764e59e5134cb0b 507 Gene3D G3DSA:3.40.605.10 24 493 1.9E-160 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 MB46_02825 568c2f0fbb07e35c9764e59e5134cb0b 507 Gene3D G3DSA:3.40.309.10 267 465 1.9E-160 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 MB46_02825 568c2f0fbb07e35c9764e59e5134cb0b 507 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 295 306 - T 14-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 MB46_02825 568c2f0fbb07e35c9764e59e5134cb0b 507 SUPERFAMILY SSF53720 16 499 2.75E-161 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 MB46_04445 b2d1496dec4e3fae959dc6dc09d491b6 279 Pfam PF02616 Segregation and condensation protein ScpA 16 255 3.4E-46 T 14-10-2018 IPR003768 Segregation and condensation protein A MB46_01765 97321ebd9c6bb38b016726c16c69c139 401 Pfam PF12802 MarR family 30 81 3.2E-7 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MB46_01765 97321ebd9c6bb38b016726c16c69c139 401 Pfam PF00480 ROK family 96 392 2.2E-60 T 14-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 MB46_01765 97321ebd9c6bb38b016726c16c69c139 401 Gene3D G3DSA:3.30.420.40 219 378 8.4E-86 T 14-10-2018 MB46_01765 97321ebd9c6bb38b016726c16c69c139 401 SUPERFAMILY SSF46785 25 82 2.5E-11 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_01765 97321ebd9c6bb38b016726c16c69c139 401 Gene3D G3DSA:3.30.420.40 101 388 8.4E-86 T 14-10-2018 MB46_01765 97321ebd9c6bb38b016726c16c69c139 401 Gene3D G3DSA:1.10.10.10 13 88 5.7E-14 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_01765 97321ebd9c6bb38b016726c16c69c139 401 SUPERFAMILY SSF53067 96 394 5.37E-55 T 14-10-2018 MB46_01765 97321ebd9c6bb38b016726c16c69c139 401 ProSitePatterns PS01125 ROK family signature. 229 256 - T 14-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 MB46_10545 6ddf94dd2c51402925bd238a12365721 269 Gene3D G3DSA:3.40.50.300 7 260 1.3E-61 T 14-10-2018 MB46_10545 6ddf94dd2c51402925bd238a12365721 269 SMART SM00382 33 234 3.6E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_10545 6ddf94dd2c51402925bd238a12365721 269 Pfam PF00005 ABC transporter 24 185 2.5E-35 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_10545 6ddf94dd2c51402925bd238a12365721 269 TIGRFAM TIGR02315 ABC_phnC: phosphonate ABC transporter, ATP-binding protein 8 254 1.1E-95 T 14-10-2018 IPR012693 ABC transporter, phosphonate import, PhnC GO:0005524|GO:0015416|GO:0015716|GO:0016020 MB46_10545 6ddf94dd2c51402925bd238a12365721 269 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_10545 6ddf94dd2c51402925bd238a12365721 269 SUPERFAMILY SSF52540 8 243 1.1E-58 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_14640 5b9a5bb270e734d9a0afb253e5a27400 420 TIGRFAM TIGR03071 couple_hipA: HipA N-terminal domain 12 113 1.5E-15 T 14-10-2018 IPR017508 HipA, N-terminal subdomain 1 MB46_14640 5b9a5bb270e734d9a0afb253e5a27400 420 Pfam PF13657 HipA N-terminal domain 15 112 2.2E-11 T 14-10-2018 IPR017508 HipA, N-terminal subdomain 1 MB46_14640 5b9a5bb270e734d9a0afb253e5a27400 420 Pfam PF07804 HipA-like C-terminal domain 150 388 3.8E-35 T 14-10-2018 IPR012893 HipA-like, C-terminal MB46_17025 c5d41af0d91d52c1fed2966b2cfe7ee8 86 Pfam PF08410 Domain of unknown function (DUF1737) 9 55 3.9E-20 T 14-10-2018 IPR013619 Domain of unknown function DUF1737 MB46_09415 d303c941cb506494f0f3f5834a8dea84 312 Gene3D G3DSA:3.40.50.720 22 190 5.7E-42 T 14-10-2018 MB46_09415 d303c941cb506494f0f3f5834a8dea84 312 Gene3D G3DSA:1.10.1040.10 191 312 6.0E-33 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MB46_09415 d303c941cb506494f0f3f5834a8dea84 312 PIRSF PIRSF000103 15 312 1.1E-61 T 14-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 MB46_09415 d303c941cb506494f0f3f5834a8dea84 312 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 188 302 1.1E-27 T 14-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 MB46_09415 d303c941cb506494f0f3f5834a8dea84 312 SUPERFAMILY SSF48179 187 307 1.7E-32 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MB46_09415 d303c941cb506494f0f3f5834a8dea84 312 SUPERFAMILY SSF51735 23 186 3.51E-34 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_09415 d303c941cb506494f0f3f5834a8dea84 312 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 25 38 - T 14-10-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 MB46_09415 d303c941cb506494f0f3f5834a8dea84 312 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 23 182 2.2E-38 T 14-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 MB46_12575 5a606cb0da3cd9d2ee5f0383bc6e4273 295 Pfam PF05661 Protein of unknown function (DUF808) 7 278 7.8E-97 T 14-10-2018 IPR008526 Inner membrane protein YedI MB46_12575 5a606cb0da3cd9d2ee5f0383bc6e4273 295 PIRSF PIRSF016660 3 291 7.6E-93 T 14-10-2018 IPR008526 Inner membrane protein YedI MB46_06215 93d3fc47dc637a246b269a2f921b6b81 313 Gene3D G3DSA:1.10.3720.10 69 309 7.2E-70 T 14-10-2018 IPR035906 MetI-like superfamily MB46_06215 93d3fc47dc637a246b269a2f921b6b81 313 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 105 307 2.6E-16 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_06215 93d3fc47dc637a246b269a2f921b6b81 313 SUPERFAMILY SSF161098 73 300 8.76E-62 T 14-10-2018 IPR035906 MetI-like superfamily MB46_17125 d3c82052e93497fdaa3846a8bcf0a6ad 1168 Pfam PF08455 Bacterial SNF2 helicase associated 385 645 1.8E-8 T 14-10-2018 IPR013663 Helicase, SWF/SNF/SWI type, bacterial MB46_17125 d3c82052e93497fdaa3846a8bcf0a6ad 1168 Gene3D G3DSA:3.40.50.300 928 1126 1.2E-72 T 14-10-2018 MB46_17125 d3c82052e93497fdaa3846a8bcf0a6ad 1168 Pfam PF00176 SNF2 family N-terminal domain 702 982 7.1E-53 T 14-10-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 MB46_17125 d3c82052e93497fdaa3846a8bcf0a6ad 1168 Gene3D G3DSA:3.40.50.10810 685 922 5.4E-59 T 14-10-2018 IPR038718 SNF2-like, N-terminal domain superfamily MB46_17125 d3c82052e93497fdaa3846a8bcf0a6ad 1168 SUPERFAMILY SSF52540 656 921 2.6E-50 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_17125 d3c82052e93497fdaa3846a8bcf0a6ad 1168 Pfam PF00271 Helicase conserved C-terminal domain 1003 1112 3.5E-15 T 14-10-2018 IPR001650 Helicase, C-terminal MB46_17125 d3c82052e93497fdaa3846a8bcf0a6ad 1168 SUPERFAMILY SSF52540 922 1167 1.23E-57 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_17125 d3c82052e93497fdaa3846a8bcf0a6ad 1168 SMART SM00487 680 893 1.2E-21 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MB46_17125 d3c82052e93497fdaa3846a8bcf0a6ad 1168 SMART SM00490 1032 1112 1.6E-19 T 14-10-2018 IPR001650 Helicase, C-terminal MB46_17125 d3c82052e93497fdaa3846a8bcf0a6ad 1168 Gene3D G3DSA:1.20.120.850 943 1161 1.2E-72 T 14-10-2018 MB46_01565 f3a4e4739a7aede55a05b1c7d4f048a2 286 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 8 211 5.6E-19 T 14-10-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 MB46_12595 47972a045d093165e4c088ef1915f405 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 110 129 7.6E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_12595 47972a045d093165e4c088ef1915f405 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 37 48 7.6E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_12595 47972a045d093165e4c088ef1915f405 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 100 7.6E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_12595 47972a045d093165e4c088ef1915f405 241 Pfam PF00106 short chain dehydrogenase 9 150 2.8E-31 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_12595 47972a045d093165e4c088ef1915f405 241 SUPERFAMILY SSF51735 3 205 5.5E-39 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_12595 47972a045d093165e4c088ef1915f405 241 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 37 48 2.7E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_12595 47972a045d093165e4c088ef1915f405 241 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 110 129 2.7E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_12595 47972a045d093165e4c088ef1915f405 241 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 90 98 2.7E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_12595 47972a045d093165e4c088ef1915f405 241 Gene3D G3DSA:3.40.50.720 1 233 2.4E-43 T 14-10-2018 MB46_01965 10f460ae898be48906e75a23a49762f5 138 TIGRFAM TIGR01354 cyt_deam_tetra: cytidine deaminase 11 128 2.8E-37 T 14-10-2018 IPR006262 Cytidine deaminase, homotetrameric GO:0004126|GO:0008270|GO:0009972 KEGG: 00240+3.5.4.5|KEGG: 00983+3.5.4.5|MetaCyc: PWY-6556|MetaCyc: PWY-7181|MetaCyc: PWY-7193|MetaCyc: PWY-7199|Reactome: R-HSA-6798695|Reactome: R-HSA-73614 MB46_01965 10f460ae898be48906e75a23a49762f5 138 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 14 103 5.3E-11 T 14-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain MB46_01965 10f460ae898be48906e75a23a49762f5 138 Gene3D G3DSA:3.40.140.10 1 132 1.8E-47 T 14-10-2018 MB46_01965 10f460ae898be48906e75a23a49762f5 138 SUPERFAMILY SSF53927 2 129 4.12E-40 T 14-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 MB46_08175 054610e92158fd46169355326012cf17 455 Gene3D G3DSA:3.40.50.1980 46 257 4.8E-104 T 14-10-2018 MB46_08175 054610e92158fd46169355326012cf17 455 Gene3D G3DSA:3.40.50.1980 259 376 4.8E-104 T 14-10-2018 MB46_08175 054610e92158fd46169355326012cf17 455 SUPERFAMILY SSF53720 38 453 4.02E-68 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 MB46_08175 054610e92158fd46169355326012cf17 455 Pfam PF00815 Histidinol dehydrogenase 38 454 1.4E-149 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MB46_08175 054610e92158fd46169355326012cf17 455 PIRSF PIRSF000099 15 455 3.5E-139 T 14-10-2018 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MB46_08175 054610e92158fd46169355326012cf17 455 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 48 453 6.7E-137 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MB46_08175 054610e92158fd46169355326012cf17 455 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 19 454 38.0 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MB46_08175 054610e92158fd46169355326012cf17 455 PRINTS PR00083 Histidinol dehydrogenase signature 186 212 2.8E-68 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MB46_08175 054610e92158fd46169355326012cf17 455 PRINTS PR00083 Histidinol dehydrogenase signature 149 175 2.8E-68 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MB46_08175 054610e92158fd46169355326012cf17 455 PRINTS PR00083 Histidinol dehydrogenase signature 347 372 2.8E-68 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MB46_08175 054610e92158fd46169355326012cf17 455 PRINTS PR00083 Histidinol dehydrogenase signature 48 72 2.8E-68 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MB46_08175 054610e92158fd46169355326012cf17 455 PRINTS PR00083 Histidinol dehydrogenase signature 255 276 2.8E-68 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MB46_08175 054610e92158fd46169355326012cf17 455 PRINTS PR00083 Histidinol dehydrogenase signature 277 296 2.8E-68 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MB46_08175 054610e92158fd46169355326012cf17 455 PRINTS PR00083 Histidinol dehydrogenase signature 388 406 2.8E-68 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MB46_13550 27d10eefa3aba5586699e816d179bbad 430 Pfam PF04024 PspC domain 4 58 2.6E-13 T 14-10-2018 IPR007168 Phage shock protein, PspC, N-terminal MB46_13550 27d10eefa3aba5586699e816d179bbad 430 Gene3D G3DSA:3.30.565.10 311 421 4.4E-13 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MB46_13550 27d10eefa3aba5586699e816d179bbad 430 SUPERFAMILY SSF55874 335 420 9.72E-10 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MB46_13280 5dcde44e089c137cc242789198f1f399 336 Gene3D G3DSA:1.10.150.20 224 329 9.6E-28 T 14-10-2018 MB46_13280 5dcde44e089c137cc242789198f1f399 336 SUPERFAMILY SSF55257 15 220 3.27E-24 T 14-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MB46_13280 5dcde44e089c137cc242789198f1f399 336 Gene3D G3DSA:3.30.1360.10 14 216 1.8E-81 T 14-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MB46_13280 5dcde44e089c137cc242789198f1f399 336 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 59 150 2.5E-23 T 14-10-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MB46_13280 5dcde44e089c137cc242789198f1f399 336 SUPERFAMILY SSF56553 48 169 6.28E-42 T 14-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MB46_13280 5dcde44e089c137cc242789198f1f399 336 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 24 218 3.8E-19 T 14-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MB46_13280 5dcde44e089c137cc242789198f1f399 336 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 246 302 1.4E-25 T 14-10-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MB46_13280 5dcde44e089c137cc242789198f1f399 336 SMART SM00662 18 225 3.9E-89 T 14-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MB46_13280 5dcde44e089c137cc242789198f1f399 336 SUPERFAMILY SSF47789 248 316 2.35E-23 T 14-10-2018 MB46_13280 5dcde44e089c137cc242789198f1f399 336 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 19 310 1.9E-113 T 14-10-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MB46_13280 5dcde44e089c137cc242789198f1f399 336 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 3 311 33.798 T 14-10-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MB46_13280 5dcde44e089c137cc242789198f1f399 336 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 250 313 2.0E-29 T 14-10-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MB46_13280 5dcde44e089c137cc242789198f1f399 336 Gene3D G3DSA:2.170.120.12 48 168 1.8E-81 T 14-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MB46_09775 c2bfd8659b1952595a3335625ffd4138 171 Gene3D G3DSA:3.40.50.620 1 157 1.5E-49 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MB46_09775 c2bfd8659b1952595a3335625ffd4138 171 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 3 154 9.4E-51 T 14-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 MB46_09775 c2bfd8659b1952595a3335625ffd4138 171 Pfam PF01467 Cytidylyltransferase-like 6 133 1.3E-16 T 14-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 MB46_09775 c2bfd8659b1952595a3335625ffd4138 171 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 20 41 2.0E-36 T 14-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 MB46_09775 c2bfd8659b1952595a3335625ffd4138 171 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 49 73 2.0E-36 T 14-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 MB46_09775 c2bfd8659b1952595a3335625ffd4138 171 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 112 134 2.0E-36 T 14-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 MB46_09775 c2bfd8659b1952595a3335625ffd4138 171 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 86 102 2.0E-36 T 14-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 MB46_09775 c2bfd8659b1952595a3335625ffd4138 171 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 2 20 2.0E-36 T 14-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 MB46_09775 c2bfd8659b1952595a3335625ffd4138 171 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 2 158 29.892 T 14-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 MB46_09775 c2bfd8659b1952595a3335625ffd4138 171 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 3 55 3.2E-16 T 14-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 MB46_09775 c2bfd8659b1952595a3335625ffd4138 171 SUPERFAMILY SSF52374 1 153 1.1E-40 T 14-10-2018 MB46_18360 466b43e84256ea20b2a723c5671679d4 237 Pfam PF02592 Putative vitamin uptake transporter 60 222 2.1E-39 T 14-10-2018 IPR003744 Queuosine precursor transporter GO:1990397 MB46_18360 466b43e84256ea20b2a723c5671679d4 237 Hamap MF_02088 Probable queuosine precursor transporter. 27 236 14.807 T 14-10-2018 IPR003744 Queuosine precursor transporter GO:1990397 MB46_18360 466b43e84256ea20b2a723c5671679d4 237 TIGRFAM TIGR00697 TIGR00697: conserved hypothetical integral membrane protein 33 225 4.5E-25 T 14-10-2018 IPR003744 Queuosine precursor transporter GO:1990397 MB46_19670 6cf5e79578a0515ac17aa415e925aa77 126 SUPERFAMILY SSF52172 7 121 5.83E-32 T 14-10-2018 IPR011006 CheY-like superfamily MB46_19670 6cf5e79578a0515ac17aa415e925aa77 126 Gene3D G3DSA:3.40.50.12740 7 125 1.2E-30 T 14-10-2018 MB46_19670 6cf5e79578a0515ac17aa415e925aa77 126 SMART SM00448 5 115 2.7E-30 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MB46_19670 6cf5e79578a0515ac17aa415e925aa77 126 Pfam PF00072 Response regulator receiver domain 8 114 2.7E-21 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MB46_14810 a0c3e0b4db22540f1753a3181762f8d4 535 PIRSF PIRSF001363 1 535 2.3E-225 T 14-10-2018 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 MB46_14810 a0c3e0b4db22540f1753a3181762f8d4 535 TIGRFAM TIGR01344 malate_syn_A: malate synthase A 20 533 5.5E-226 T 14-10-2018 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 MB46_14810 a0c3e0b4db22540f1753a3181762f8d4 535 Pfam PF01274 Malate synthase 16 533 1.7E-185 T 14-10-2018 IPR001465 Malate synthase GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 MB46_14810 a0c3e0b4db22540f1753a3181762f8d4 535 SUPERFAMILY SSF51645 15 533 2.49E-171 T 14-10-2018 IPR011076 Malate synthase-like superfamily GO:0003824 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 MB46_14810 a0c3e0b4db22540f1753a3181762f8d4 535 Gene3D G3DSA:3.20.20.360 1 411 5.4E-178 T 14-10-2018 MB46_14810 a0c3e0b4db22540f1753a3181762f8d4 535 ProSitePatterns PS00510 Malate synthase signature. 265 280 - T 14-10-2018 IPR019830 Malate synthase, conserved site GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 MB46_14810 a0c3e0b4db22540f1753a3181762f8d4 535 Gene3D G3DSA:1.20.1220.12 415 534 6.6E-40 T 14-10-2018 MB46_06705 65b69808f5272a3305e975d827dff480 465 Pfam PF14333 Domain of unknown function (DUF4389) 399 450 1.4E-9 T 14-10-2018 IPR025498 Protein of unknown function DUF4389 MB46_06705 65b69808f5272a3305e975d827dff480 465 Pfam PF14333 Domain of unknown function (DUF4389) 261 332 2.3E-10 T 14-10-2018 IPR025498 Protein of unknown function DUF4389 MB46_04905 441057ee8013bcb5f96f1d67aa11b44e 125 SUPERFAMILY SSF54593 9 125 2.55E-19 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MB46_04905 441057ee8013bcb5f96f1d67aa11b44e 125 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 12 120 1.9E-8 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MB46_04905 441057ee8013bcb5f96f1d67aa11b44e 125 Gene3D G3DSA:3.10.180.10 3 125 1.2E-23 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MB46_12290 6bc22bb661f1daf05ec06bcebe103bb0 472 Pfam PF07690 Major Facilitator Superfamily 24 250 2.8E-30 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MB46_12290 6bc22bb661f1daf05ec06bcebe103bb0 472 Pfam PF07690 Major Facilitator Superfamily 284 452 8.5E-10 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MB46_12290 6bc22bb661f1daf05ec06bcebe103bb0 472 Gene3D G3DSA:1.20.1250.20 261 464 3.7E-15 T 14-10-2018 MB46_12290 6bc22bb661f1daf05ec06bcebe103bb0 472 SUPERFAMILY SSF103473 11 463 4.84E-55 T 14-10-2018 IPR036259 MFS transporter superfamily MB46_12290 6bc22bb661f1daf05ec06bcebe103bb0 472 Gene3D G3DSA:1.20.1720.10 18 209 2.2E-48 T 14-10-2018 MB46_06255 17a3dfa56bbde0c4ce70c7a3f678adc7 201 Gene3D G3DSA:1.10.357.10 3 194 1.1E-27 T 14-10-2018 MB46_06255 17a3dfa56bbde0c4ce70c7a3f678adc7 201 SUPERFAMILY SSF46689 5 73 1.69E-14 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MB46_06255 17a3dfa56bbde0c4ce70c7a3f678adc7 201 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 101 176 2.1E-9 T 14-10-2018 IPR039538 BetI-type transcriptional repressor, C-terminal MB46_06255 17a3dfa56bbde0c4ce70c7a3f678adc7 201 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 59 9.9E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MB46_06255 17a3dfa56bbde0c4ce70c7a3f678adc7 201 SUPERFAMILY SSF48498 102 185 2.06E-6 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily MB46_05670 195764c0a114062c98137ab94f425f5e 189 SUPERFAMILY SSF52218 5 174 4.53E-42 T 14-10-2018 IPR029039 Flavoprotein-like superfamily MB46_05670 195764c0a114062c98137ab94f425f5e 189 Pfam PF03358 NADPH-dependent FMN reductase 5 148 3.5E-32 T 14-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 MB46_05670 195764c0a114062c98137ab94f425f5e 189 Gene3D G3DSA:3.40.50.360 4 184 2.8E-43 T 14-10-2018 IPR029039 Flavoprotein-like superfamily MB46_07490 bdd4a9b6a6958c2aceec7b38d0847f55 63 SUPERFAMILY SSF47413 2 61 2.76E-17 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MB46_07490 bdd4a9b6a6958c2aceec7b38d0847f55 63 SMART SM00530 4 59 3.1E-15 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MB46_07490 bdd4a9b6a6958c2aceec7b38d0847f55 63 Gene3D G3DSA:1.10.260.40 1 63 3.3E-25 T 14-10-2018 MB46_07490 bdd4a9b6a6958c2aceec7b38d0847f55 63 Pfam PF01381 Helix-turn-helix 5 57 2.3E-16 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MB46_14475 17afc38799d7da4bfa59407d03d26072 408 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 11 406 1.4E-134 T 14-10-2018 IPR002155 Thiolase GO:0016747 MB46_14475 17afc38799d7da4bfa59407d03d26072 408 PIRSF PIRSF000429 3 408 5.9E-127 T 14-10-2018 IPR002155 Thiolase GO:0016747 MB46_14475 17afc38799d7da4bfa59407d03d26072 408 Gene3D G3DSA:3.40.47.10 144 405 4.9E-145 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 MB46_14475 17afc38799d7da4bfa59407d03d26072 408 Pfam PF02803 Thiolase, C-terminal domain 285 406 6.8E-38 T 14-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 MB46_14475 17afc38799d7da4bfa59407d03d26072 408 SUPERFAMILY SSF53901 8 284 2.88E-81 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 MB46_14475 17afc38799d7da4bfa59407d03d26072 408 SUPERFAMILY SSF53901 286 406 7.88E-34 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 MB46_14475 17afc38799d7da4bfa59407d03d26072 408 ProSitePatterns PS00099 Thiolases active site. 389 402 - T 14-10-2018 IPR020610 Thiolase, active site GO:0016747 MB46_14475 17afc38799d7da4bfa59407d03d26072 408 Gene3D G3DSA:3.40.47.10 11 290 4.9E-145 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 MB46_14475 17afc38799d7da4bfa59407d03d26072 408 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 89 107 - T 14-10-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0016747 MB46_14475 17afc38799d7da4bfa59407d03d26072 408 ProSitePatterns PS00737 Thiolases signature 2. 353 369 - T 14-10-2018 IPR020613 Thiolase, conserved site GO:0016747 MB46_14475 17afc38799d7da4bfa59407d03d26072 408 Pfam PF00108 Thiolase, N-terminal domain 10 276 2.0E-77 T 14-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 MB46_00455 c8cd966ba27679cf178e47535238774a 294 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 2 140 1.6E-17 T 14-10-2018 IPR028973 PhnB-like MB46_00455 c8cd966ba27679cf178e47535238774a 294 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 154 266 7.7E-29 T 14-10-2018 IPR028973 PhnB-like MB46_00455 c8cd966ba27679cf178e47535238774a 294 SUPERFAMILY SSF54593 1 141 9.57E-20 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MB46_00455 c8cd966ba27679cf178e47535238774a 294 Gene3D G3DSA:3.10.180.70 1 151 2.2E-31 T 14-10-2018 MB46_00455 c8cd966ba27679cf178e47535238774a 294 Gene3D G3DSA:3.10.180.70 152 294 5.2E-41 T 14-10-2018 MB46_00455 c8cd966ba27679cf178e47535238774a 294 SUPERFAMILY SSF54593 165 294 3.09E-26 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MB46_17730 685b5eb53e5ab09becffc8485747afa9 370 PIRSF PIRSF001361 3 370 4.1E-150 T 14-10-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 MB46_17730 685b5eb53e5ab09becffc8485747afa9 370 Pfam PF00793 DAHP synthetase I family 53 357 7.3E-92 T 14-10-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 MB46_17730 685b5eb53e5ab09becffc8485747afa9 370 SUPERFAMILY SSF51569 16 366 5.13E-119 T 14-10-2018 MB46_17730 685b5eb53e5ab09becffc8485747afa9 370 Gene3D G3DSA:3.20.20.70 10 369 2.9E-147 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MB46_17730 685b5eb53e5ab09becffc8485747afa9 370 TIGRFAM TIGR00034 aroFGH: 3-deoxy-7-phosphoheptulonate synthase 16 368 2.1E-141 T 14-10-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 MB46_15015 4b0d09b134d2e3c0d90be64d7a678a42 296 Gene3D G3DSA:3.40.190.10 41 292 3.8E-75 T 14-10-2018 MB46_15015 4b0d09b134d2e3c0d90be64d7a678a42 296 SUPERFAMILY SSF53850 35 294 7.03E-61 T 14-10-2018 MB46_15015 4b0d09b134d2e3c0d90be64d7a678a42 296 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 37 284 2.1E-50 T 14-10-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0022857|GO:0043190|GO:0055085 MB46_15015 4b0d09b134d2e3c0d90be64d7a678a42 296 Gene3D G3DSA:3.40.190.100 120 228 3.8E-75 T 14-10-2018 MB46_08815 78eda8e5075017d957afbd78a905b301 83 SUPERFAMILY SSF52833 1 72 8.51E-19 T 14-10-2018 IPR036249 Thioredoxin-like superfamily MB46_08815 78eda8e5075017d957afbd78a905b301 83 Pfam PF00462 Glutaredoxin 3 61 9.2E-14 T 14-10-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 MB46_08815 78eda8e5075017d957afbd78a905b301 83 TIGRFAM TIGR02194 GlrX_NrdH: glutaredoxin-like protein NrdH 3 73 6.2E-33 T 14-10-2018 IPR011909 Glutaredoxin-like protein NrdH GO:0045454 MB46_08815 78eda8e5075017d957afbd78a905b301 83 Gene3D G3DSA:3.40.30.10 1 80 7.7E-29 T 14-10-2018 MB46_09570 e5792ffc0df635ba73717c4449abdf31 265 Gene3D G3DSA:3.40.1280.10 1 179 2.1E-65 T 14-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal MB46_09570 e5792ffc0df635ba73717c4449abdf31 265 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 1 234 1.9E-77 T 14-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 MB46_09570 e5792ffc0df635ba73717c4449abdf31 265 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 22 228 7.5E-64 T 14-10-2018 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 MB46_09570 e5792ffc0df635ba73717c4449abdf31 265 PIRSF PIRSF000386 1 254 1.4E-91 T 14-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 MB46_09570 e5792ffc0df635ba73717c4449abdf31 265 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 265 100.923 T 14-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 MB46_09570 e5792ffc0df635ba73717c4449abdf31 265 Gene3D G3DSA:1.10.1270.20 180 255 7.6E-27 T 14-10-2018 IPR023148 tRNA (guanine-N1-)-methyltransferase, C-terminal GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 MB46_09570 e5792ffc0df635ba73717c4449abdf31 265 SUPERFAMILY SSF75217 1 241 2.42E-89 T 14-10-2018 IPR029028 Alpha/beta knot methyltransferases MB46_09190 fa944370ddf86b4ea7c5517615c12b34 158 Gene3D G3DSA:1.10.10.10 7 156 4.5E-30 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_09190 fa944370ddf86b4ea7c5517615c12b34 158 SMART SM00347 33 136 3.3E-6 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MB46_09190 fa944370ddf86b4ea7c5517615c12b34 158 SUPERFAMILY SSF46785 4 149 6.45E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_09190 fa944370ddf86b4ea7c5517615c12b34 158 Pfam PF01047 MarR family 44 98 1.8E-7 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MB46_11710 0effa693d9a0fce941763c8329527a3a 155 SUPERFAMILY SSF109854 28 89 1.01E-6 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes MB46_04340 1c62775034069614417db4e4cf2996bc 281 SUPERFAMILY SSF161098 7 281 1.96E-64 T 14-10-2018 IPR035906 MetI-like superfamily MB46_04340 1c62775034069614417db4e4cf2996bc 281 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 85 270 2.7E-19 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_04340 1c62775034069614417db4e4cf2996bc 281 Gene3D G3DSA:1.10.3720.10 4 269 5.8E-60 T 14-10-2018 IPR035906 MetI-like superfamily MB46_07430 0194a1acc5c77e6f9ee9182e7b366dce 611 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 30 181 2.1E-16 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 MB46_07430 0194a1acc5c77e6f9ee9182e7b366dce 611 SUPERFAMILY SSF88659 130 181 3.36E-9 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like MB46_07430 0194a1acc5c77e6f9ee9182e7b366dce 611 Gene3D G3DSA:2.60.40.10 442 518 4.3E-5 T 14-10-2018 IPR013783 Immunoglobulin-like fold MB46_07430 0194a1acc5c77e6f9ee9182e7b366dce 611 Gene3D G3DSA:1.10.1740.10 9 126 5.7E-16 T 14-10-2018 MB46_07430 0194a1acc5c77e6f9ee9182e7b366dce 611 Pfam PF08281 Sigma-70, region 4 131 177 1.1E-6 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MB46_07430 0194a1acc5c77e6f9ee9182e7b366dce 611 SUPERFAMILY SSF88946 13 115 1.18E-16 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 MB46_07430 0194a1acc5c77e6f9ee9182e7b366dce 611 Gene3D G3DSA:1.10.10.10 129 186 4.0E-9 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_07430 0194a1acc5c77e6f9ee9182e7b366dce 611 Pfam PF04542 Sigma-70 region 2 35 90 1.7E-7 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 MB46_10245 b6b0ea0c9243287d6c8364373c6d5271 377 SUPERFAMILY SSF56349 74 354 1.1E-43 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MB46_10245 b6b0ea0c9243287d6c8364373c6d5271 377 Pfam PF00589 Phage integrase family 203 357 1.2E-13 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MB46_10245 b6b0ea0c9243287d6c8364373c6d5271 377 Gene3D G3DSA:1.10.443.10 175 367 8.9E-30 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 MB46_10245 b6b0ea0c9243287d6c8364373c6d5271 377 Gene3D G3DSA:1.10.150.130 70 173 1.9E-17 T 14-10-2018 IPR010998 Integrase/recombinase, N-terminal MB46_05505 a0c41483f86dc9d3d3174e26080062dc 181 Gene3D G3DSA:3.40.630.30 1 170 4.9E-41 T 14-10-2018 MB46_05505 a0c41483f86dc9d3d3174e26080062dc 181 Pfam PF13302 Acetyltransferase (GNAT) domain 9 156 2.1E-28 T 14-10-2018 IPR000182 GNAT domain MB46_05505 a0c41483f86dc9d3d3174e26080062dc 181 SUPERFAMILY SSF55729 2 166 6.67E-36 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase MB46_00715 e9ed6f9a15837a6df3dbaf4b331b6706 202 Gene3D G3DSA:3.40.50.1110 1 202 6.3E-59 T 14-10-2018 IPR036514 SGNH hydrolase superfamily MB46_00715 e9ed6f9a15837a6df3dbaf4b331b6706 202 SUPERFAMILY SSF52266 6 200 1.53E-35 T 14-10-2018 MB46_00715 e9ed6f9a15837a6df3dbaf4b331b6706 202 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 11 190 2.0E-20 T 14-10-2018 IPR013830 SGNH hydrolase-type esterase domain MB46_02950 147cbe6248b6847f123dbe5a194c3392 594 SUPERFAMILY SSF56112 14 323 5.66E-58 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily MB46_02950 147cbe6248b6847f123dbe5a194c3392 594 SMART SM00220 16 273 5.6E-46 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 MB46_02950 147cbe6248b6847f123dbe5a194c3392 594 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 135 147 - T 14-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 MB46_02950 147cbe6248b6847f123dbe5a194c3392 594 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 22 45 - T 14-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 MB46_02950 147cbe6248b6847f123dbe5a194c3392 594 Pfam PF00069 Protein kinase domain 16 232 2.9E-40 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 MB46_02950 147cbe6248b6847f123dbe5a194c3392 594 Gene3D G3DSA:1.10.510.10 11 319 7.8E-57 T 14-10-2018 MB46_18815 43ab2c60a6211914fc2250d250619e9d 149 Pfam PF02082 Transcriptional regulator 2 82 4.4E-15 T 14-10-2018 IPR000944 Transcription regulator Rrf2-type MB46_18815 43ab2c60a6211914fc2250d250619e9d 149 Gene3D G3DSA:1.10.10.10 1 140 3.8E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_18815 43ab2c60a6211914fc2250d250619e9d 149 SUPERFAMILY SSF46785 2 133 1.86E-25 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_18815 43ab2c60a6211914fc2250d250619e9d 149 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 49 67 - T 14-10-2018 IPR030489 Transcription regulator Rrf2-type, conserved site MB46_09990 6f137955480b77361aadc32769d8e633 161 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 22 159 4.3E-21 T 14-10-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like MB46_09990 6f137955480b77361aadc32769d8e633 161 Gene3D G3DSA:3.30.530.20 2 161 1.0E-43 T 14-10-2018 IPR023393 START-like domain superfamily MB46_09990 6f137955480b77361aadc32769d8e633 161 SUPERFAMILY SSF55961 11 160 4.12E-34 T 14-10-2018 MB46_11830 d6980d8b89075308173e4148419e0f3d 327 Pfam PF13460 NAD(P)H-binding 11 162 2.6E-10 T 14-10-2018 IPR016040 NAD(P)-binding domain MB46_11830 d6980d8b89075308173e4148419e0f3d 327 Gene3D G3DSA:3.40.50.720 2 315 4.0E-36 T 14-10-2018 MB46_11830 d6980d8b89075308173e4148419e0f3d 327 SUPERFAMILY SSF51735 3 308 7.45E-39 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_11825 a5048af2767c1b092b2e4a8688cebf74 323 Gene3D G3DSA:3.20.20.100 1 323 7.9E-103 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily MB46_11825 a5048af2767c1b092b2e4a8688cebf74 323 Pfam PF00248 Aldo/keto reductase family 16 310 2.8E-66 T 14-10-2018 IPR023210 NADP-dependent oxidoreductase domain MB46_11825 a5048af2767c1b092b2e4a8688cebf74 323 SUPERFAMILY SSF51430 1 313 7.2E-90 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily MB46_14220 9a455d21f764245b374892de7a5279d1 246 SUPERFAMILY SSF46785 174 238 3.81E-9 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_14220 9a455d21f764245b374892de7a5279d1 246 Gene3D G3DSA:3.90.79.10 24 167 3.5E-42 T 14-10-2018 MB46_14220 9a455d21f764245b374892de7a5279d1 246 ProSitePatterns PS00893 Nudix box signature. 61 82 - T 14-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 MB46_14220 9a455d21f764245b374892de7a5279d1 246 Pfam PF00293 NUDIX domain 31 159 3.4E-18 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MB46_14220 9a455d21f764245b374892de7a5279d1 246 Gene3D G3DSA:1.10.10.10 168 238 3.6E-16 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_14220 9a455d21f764245b374892de7a5279d1 246 SUPERFAMILY SSF55811 13 171 1.35E-28 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 MB46_06650 11fbd2520ccb819d27e930fbbe4d93c3 257 SUPERFAMILY SSF52317 1 221 7.45E-67 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like MB46_06650 11fbd2520ccb819d27e930fbbe4d93c3 257 Gene3D G3DSA:3.40.50.880 1 222 6.4E-71 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like MB46_06650 11fbd2520ccb819d27e930fbbe4d93c3 257 Pfam PF01965 DJ-1/PfpI family 24 213 5.0E-16 T 14-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 MB46_19650 31850de90558d3a08b291b8e0f4ee0b5 109 Pfam PF06305 Lipopolysaccharide assembly protein A domain 54 108 1.1E-5 T 14-10-2018 IPR010445 Lipopolysaccharide assembly protein A domain GO:0005887 MB46_19820 c8bb4d39a97218b971534a3eca1bd8db 423 Pfam PF00817 impB/mucB/samB family 7 150 6.1E-31 T 14-10-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 MB46_19820 c8bb4d39a97218b971534a3eca1bd8db 423 SUPERFAMILY SSF56672 4 239 8.63E-62 T 14-10-2018 MB46_19820 c8bb4d39a97218b971534a3eca1bd8db 423 Gene3D G3DSA:2.30.40.20 12 75 1.2E-39 T 14-10-2018 MB46_19820 c8bb4d39a97218b971534a3eca1bd8db 423 Gene3D G3DSA:3.30.70.270 4 156 1.2E-39 T 14-10-2018 MB46_19820 c8bb4d39a97218b971534a3eca1bd8db 423 Pfam PF11799 impB/mucB/samB family C-terminal domain 247 354 8.1E-7 T 14-10-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 MB46_19820 c8bb4d39a97218b971534a3eca1bd8db 423 Gene3D G3DSA:1.10.150.20 173 230 1.6E-7 T 14-10-2018 MB46_19820 c8bb4d39a97218b971534a3eca1bd8db 423 Pfam PF13438 Domain of unknown function (DUF4113) 372 419 9.9E-17 T 14-10-2018 IPR025188 Domain of unknown function DUF4113 MB46_00475 f5fe8926dc41f07e1b769bd368af86b6 328 Pfam PF00248 Aldo/keto reductase family 15 305 5.1E-71 T 14-10-2018 IPR023210 NADP-dependent oxidoreductase domain MB46_00475 f5fe8926dc41f07e1b769bd368af86b6 328 SUPERFAMILY SSF51430 3 307 1.26E-93 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily MB46_00475 f5fe8926dc41f07e1b769bd368af86b6 328 Gene3D G3DSA:3.20.20.100 2 327 2.6E-108 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily MB46_04580 1d2d3a01b70aaf20fce592b83c633074 86 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 85 15.795 T 14-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 MB46_04580 1d2d3a01b70aaf20fce592b83c633074 86 Gene3D G3DSA:1.20.58.110 1 86 3.0E-27 T 14-10-2018 IPR036510 Ribosomal protein S20 superfamily GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 MB46_04580 1d2d3a01b70aaf20fce592b83c633074 86 Pfam PF01649 Ribosomal protein S20 2 84 1.2E-24 T 14-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 MB46_04580 1d2d3a01b70aaf20fce592b83c633074 86 TIGRFAM TIGR00029 S20: ribosomal protein bS20 2 85 3.6E-22 T 14-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 MB46_04580 1d2d3a01b70aaf20fce592b83c633074 86 SUPERFAMILY SSF46992 3 86 2.49E-26 T 14-10-2018 IPR036510 Ribosomal protein S20 superfamily GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 MB46_04580 1d2d3a01b70aaf20fce592b83c633074 86 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 14 86 7.0E-6 T 14-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 MB46_13350 007b9879472b839ca811298b04b872a5 70 ProSitePatterns PS00634 Ribosomal protein L30 signature. 32 64 - T 14-10-2018 IPR018038 Ribosomal protein L30, conserved site MB46_13350 007b9879472b839ca811298b04b872a5 70 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 14 68 2.1E-18 T 14-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_13350 007b9879472b839ca811298b04b872a5 70 Gene3D G3DSA:3.30.1390.20 11 68 6.5E-20 T 14-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily MB46_13350 007b9879472b839ca811298b04b872a5 70 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 11 68 16.587 T 14-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_13350 007b9879472b839ca811298b04b872a5 70 PIRSF PIRSF002211 9 70 6.8E-24 T 14-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_13350 007b9879472b839ca811298b04b872a5 70 SUPERFAMILY SSF55129 14 68 1.26E-16 T 14-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily MB46_13350 007b9879472b839ca811298b04b872a5 70 Pfam PF00327 Ribosomal protein L30p/L7e 15 64 5.9E-14 T 14-10-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain MB46_05870 eb86d5fbbb5644e378cf084e218699bc 355 SUPERFAMILY SSF51395 2 353 1.74E-108 T 14-10-2018 MB46_05870 eb86d5fbbb5644e378cf084e218699bc 355 Gene3D G3DSA:3.20.20.70 1 355 2.3E-119 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MB46_05870 eb86d5fbbb5644e378cf084e218699bc 355 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 2 332 1.3E-71 T 14-10-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 MB46_11260 39bd4ccdbde06e1e37f6da0c44a17302 256 SUPERFAMILY SSF53335 20 239 2.37E-29 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MB46_11260 39bd4ccdbde06e1e37f6da0c44a17302 256 Gene3D G3DSA:3.40.50.150 24 236 2.1E-36 T 14-10-2018 MB46_11260 39bd4ccdbde06e1e37f6da0c44a17302 256 Pfam PF08241 Methyltransferase domain 55 143 7.5E-19 T 14-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 MB46_19905 04682e5faab6b949e9b177b3d2ff5986 493 Gene3D G3DSA:3.40.50.1110 281 493 1.8E-19 T 14-10-2018 IPR036514 SGNH hydrolase superfamily MB46_19905 04682e5faab6b949e9b177b3d2ff5986 493 SUPERFAMILY SSF52266 310 492 2.9E-21 T 14-10-2018 MB46_19905 04682e5faab6b949e9b177b3d2ff5986 493 Pfam PF08310 LGFP repeat 57 111 1.1E-8 T 14-10-2018 IPR013207 LGFP MB46_19905 04682e5faab6b949e9b177b3d2ff5986 493 Pfam PF08310 LGFP repeat 113 164 5.2E-14 T 14-10-2018 IPR013207 LGFP MB46_19905 04682e5faab6b949e9b177b3d2ff5986 493 Pfam PF08310 LGFP repeat 166 219 3.4E-16 T 14-10-2018 IPR013207 LGFP MB46_19905 04682e5faab6b949e9b177b3d2ff5986 493 Pfam PF08310 LGFP repeat 221 265 1.1E-6 T 14-10-2018 IPR013207 LGFP MB46_19905 04682e5faab6b949e9b177b3d2ff5986 493 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 316 479 1.2E-14 T 14-10-2018 IPR013830 SGNH hydrolase-type esterase domain MB46_15400 658c98be9720291f83dac7273135d2d0 317 SUPERFAMILY SSF52980 234 309 6.43E-5 T 14-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 MB46_15400 658c98be9720291f83dac7273135d2d0 317 Gene3D G3DSA:3.40.960.10 205 310 2.2E-12 T 14-10-2018 MB46_17820 6f394693d5299c37d66511e476161f3f 172 SMART SM00347 35 135 5.5E-7 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MB46_17820 6f394693d5299c37d66511e476161f3f 172 PRINTS PR00598 Bacterial regulatory protein MarR family signature 95 111 6.0E-10 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MB46_17820 6f394693d5299c37d66511e476161f3f 172 PRINTS PR00598 Bacterial regulatory protein MarR family signature 59 75 6.0E-10 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MB46_17820 6f394693d5299c37d66511e476161f3f 172 PRINTS PR00598 Bacterial regulatory protein MarR family signature 76 91 6.0E-10 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MB46_17820 6f394693d5299c37d66511e476161f3f 172 PRINTS PR00598 Bacterial regulatory protein MarR family signature 125 145 6.0E-10 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MB46_17820 6f394693d5299c37d66511e476161f3f 172 Gene3D G3DSA:1.10.10.10 12 149 8.4E-27 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_17820 6f394693d5299c37d66511e476161f3f 172 SUPERFAMILY SSF46785 17 145 1.56E-25 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_17820 6f394693d5299c37d66511e476161f3f 172 Pfam PF12802 MarR family 48 99 2.8E-9 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MB46_02660 28f3687244c4a29a91a8655b03b46f67 264 Pfam PF00072 Response regulator receiver domain 3 110 3.9E-25 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MB46_02660 28f3687244c4a29a91a8655b03b46f67 264 SUPERFAMILY SSF52172 3 119 1.71E-36 T 14-10-2018 IPR011006 CheY-like superfamily MB46_02660 28f3687244c4a29a91a8655b03b46f67 264 SMART SM00448 3 110 2.8E-37 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MB46_02660 28f3687244c4a29a91a8655b03b46f67 264 Pfam PF00486 Transcriptional regulatory protein, C terminal 179 262 2.6E-22 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MB46_02660 28f3687244c4a29a91a8655b03b46f67 264 Gene3D G3DSA:3.40.50.2300 2 120 2.1E-34 T 14-10-2018 MB46_02660 28f3687244c4a29a91a8655b03b46f67 264 Gene3D G3DSA:1.10.10.10 156 264 2.5E-33 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_02660 28f3687244c4a29a91a8655b03b46f67 264 SUPERFAMILY SSF46894 164 263 1.19E-22 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MB46_02660 28f3687244c4a29a91a8655b03b46f67 264 SMART SM00862 179 262 5.4E-24 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MB46_16030 86549f2853d35fbdcad8147574d27c98 611 Pfam PF03023 MviN-like protein 98 545 4.7E-63 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ MB46_16030 86549f2853d35fbdcad8147574d27c98 611 PRINTS PR01806 Virulence factor MviN signature 97 116 8.6E-14 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ MB46_16030 86549f2853d35fbdcad8147574d27c98 611 PRINTS PR01806 Virulence factor MviN signature 216 237 8.6E-14 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ MB46_16030 86549f2853d35fbdcad8147574d27c98 611 PRINTS PR01806 Virulence factor MviN signature 343 369 8.6E-14 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ MB46_16030 86549f2853d35fbdcad8147574d27c98 611 PRINTS PR01806 Virulence factor MviN signature 438 457 8.6E-14 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ MB46_16030 86549f2853d35fbdcad8147574d27c98 611 PRINTS PR01806 Virulence factor MviN signature 116 132 8.6E-14 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ MB46_16030 86549f2853d35fbdcad8147574d27c98 611 PRINTS PR01806 Virulence factor MviN signature 192 216 8.6E-14 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ MB46_06230 431ae7e067a9be7d678cc75ed97f4eea 254 Pfam PF01061 ABC-2 type transporter 11 217 1.1E-21 T 14-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 MB46_06230 431ae7e067a9be7d678cc75ed97f4eea 254 PIRSF PIRSF006648 1 254 9.9E-66 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 MB46_05155 f7e4d76b8ead094c07fdd17642f8859b 116 Gene3D G3DSA:3.30.300.130 11 111 2.2E-29 T 14-10-2018 IPR034904 Fe-S cluster assembly domain superfamily MB46_05155 f7e4d76b8ead094c07fdd17642f8859b 116 Pfam PF01883 Iron-sulfur cluster assembly protein 19 80 5.5E-17 T 14-10-2018 IPR002744 MIP18 family-like MB46_05155 f7e4d76b8ead094c07fdd17642f8859b 116 SUPERFAMILY SSF117916 18 110 1.6E-26 T 14-10-2018 IPR034904 Fe-S cluster assembly domain superfamily MB46_06900 63eec8e429158781517aba27a40ff2f9 361 SUPERFAMILY SSF52540 5 247 3.77E-81 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_06900 63eec8e429158781517aba27a40ff2f9 361 SUPERFAMILY SSF55021 278 341 2.75E-8 T 14-10-2018 MB46_06900 63eec8e429158781517aba27a40ff2f9 361 SMART SM00930 269 344 1.6E-6 T 14-10-2018 IPR018449 NIL domain MB46_06900 63eec8e429158781517aba27a40ff2f9 361 Pfam PF09383 NIL domain 279 335 1.5E-6 T 14-10-2018 IPR018449 NIL domain MB46_06900 63eec8e429158781517aba27a40ff2f9 361 SMART SM00382 37 225 1.2E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_06900 63eec8e429158781517aba27a40ff2f9 361 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_06900 63eec8e429158781517aba27a40ff2f9 361 Gene3D G3DSA:3.40.50.300 1 288 5.0E-86 T 14-10-2018 MB46_06900 63eec8e429158781517aba27a40ff2f9 361 Pfam PF00005 ABC transporter 29 176 9.1E-36 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_17105 303380b3771ffcb3be1240f66aa94f73 430 Gene3D G3DSA:3.40.190.10 40 429 5.7E-56 T 14-10-2018 MB46_17105 303380b3771ffcb3be1240f66aa94f73 430 Pfam PF13416 Bacterial extracellular solute-binding protein 62 356 5.4E-30 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein MB46_17105 303380b3771ffcb3be1240f66aa94f73 430 SUPERFAMILY SSF53850 20 428 1.95E-53 T 14-10-2018 MB46_17335 381d71eaf638791f842c02d9e00b1d2b 394 SUPERFAMILY SSF50494 191 376 7.83E-36 T 14-10-2018 IPR009003 Peptidase S1, PA clan MB46_17335 381d71eaf638791f842c02d9e00b1d2b 394 Pfam PF13365 Trypsin-like peptidase domain 216 352 3.2E-21 T 14-10-2018 MB46_17335 381d71eaf638791f842c02d9e00b1d2b 394 PRINTS PR00834 HtrA/DegQ protease family signature 224 236 1.7E-8 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MB46_17335 381d71eaf638791f842c02d9e00b1d2b 394 PRINTS PR00834 HtrA/DegQ protease family signature 245 265 1.7E-8 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MB46_17335 381d71eaf638791f842c02d9e00b1d2b 394 PRINTS PR00834 HtrA/DegQ protease family signature 323 340 1.7E-8 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MB46_17335 381d71eaf638791f842c02d9e00b1d2b 394 PRINTS PR00834 HtrA/DegQ protease family signature 345 362 1.7E-8 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MB46_17335 381d71eaf638791f842c02d9e00b1d2b 394 Pfam PF02674 Colicin V production protein 7 146 1.6E-14 T 14-10-2018 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 MB46_17335 381d71eaf638791f842c02d9e00b1d2b 394 Gene3D G3DSA:2.40.10.10 185 275 3.5E-20 T 14-10-2018 MB46_17335 381d71eaf638791f842c02d9e00b1d2b 394 Gene3D G3DSA:2.40.10.10 278 379 7.1E-20 T 14-10-2018 MB46_09410 eb52e21eeeffc710d2d59979b085c11d 256 Gene3D G3DSA:3.40.50.720 1 255 2.5E-73 T 14-10-2018 MB46_09410 eb52e21eeeffc710d2d59979b085c11d 256 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 253 4.2E-56 T 14-10-2018 MB46_09410 eb52e21eeeffc710d2d59979b085c11d 256 SUPERFAMILY SSF51735 4 254 6.8E-74 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_09410 eb52e21eeeffc710d2d59979b085c11d 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 160 179 2.0E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_09410 eb52e21eeeffc710d2d59979b085c11d 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 148 2.0E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_09410 eb52e21eeeffc710d2d59979b085c11d 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 87 98 2.0E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_09410 eb52e21eeeffc710d2d59979b085c11d 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 2.1E-40 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_09410 eb52e21eeeffc710d2d59979b085c11d 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 2.1E-40 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_09410 eb52e21eeeffc710d2d59979b085c11d 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 2.1E-40 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_09410 eb52e21eeeffc710d2d59979b085c11d 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 87 98 2.1E-40 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_09410 eb52e21eeeffc710d2d59979b085c11d 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 2.1E-40 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_09410 eb52e21eeeffc710d2d59979b085c11d 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 2.1E-40 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_09410 eb52e21eeeffc710d2d59979b085c11d 256 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 10 191 0.0084 T 14-10-2018 MB46_15150 77797b3bc15dba81c0b4095d46e3f973 484 Pfam PF00860 Permease family 29 413 4.4E-27 T 14-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 MB46_08255 d0692495efce7e0e09ac6be92d961a14 370 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 19 359 2.5E-87 T 14-10-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MB46_08255 d0692495efce7e0e09ac6be92d961a14 370 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 3 363 22.103 T 14-10-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MB46_08255 d0692495efce7e0e09ac6be92d961a14 370 Pfam PF00953 Glycosyl transferase family 4 88 288 6.9E-33 T 14-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 MB46_08255 d0692495efce7e0e09ac6be92d961a14 370 Pfam PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 46 58 6.3E-5 T 14-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MB46_08255 d0692495efce7e0e09ac6be92d961a14 370 ProSitePatterns PS01348 MraY family signature 2. 188 199 - T 14-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MB46_11865 89fb18cf3284060ca3ffdd944e0220de 258 Gene3D G3DSA:3.90.226.10 3 200 2.5E-73 T 14-10-2018 MB46_11865 89fb18cf3284060ca3ffdd944e0220de 258 Gene3D G3DSA:1.10.12.10 201 257 2.2E-23 T 14-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal MB46_11865 89fb18cf3284060ca3ffdd944e0220de 258 Pfam PF00378 Enoyl-CoA hydratase/isomerase 12 257 1.4E-76 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 MB46_11865 89fb18cf3284060ca3ffdd944e0220de 258 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 99 119 - T 14-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 MB46_11865 89fb18cf3284060ca3ffdd944e0220de 258 SUPERFAMILY SSF52096 2 258 1.23E-85 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MB46_12325 8f86e2355d198902ec0b7f99c1adf593 166 Pfam PF13671 AAA domain 4 122 1.9E-11 T 14-10-2018 MB46_12325 8f86e2355d198902ec0b7f99c1adf593 166 SUPERFAMILY SSF52540 4 161 7.86E-14 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_12325 8f86e2355d198902ec0b7f99c1adf593 166 Gene3D G3DSA:3.40.50.300 2 166 4.1E-25 T 14-10-2018 MB46_08840 f56461213dfce821e1379b59115cc5b9 468 PIRSF PIRSF036492 1 467 4.8E-173 T 14-10-2018 IPR012394 Aldehyde dehydrogenase NAD(P)-dependent GO:0006081|GO:0055114 MB46_08840 f56461213dfce821e1379b59115cc5b9 468 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 205 212 - T 14-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 MB46_08840 f56461213dfce821e1379b59115cc5b9 468 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 233 244 - T 14-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 MB46_08840 f56461213dfce821e1379b59115cc5b9 468 Pfam PF00171 Aldehyde dehydrogenase family 2 430 1.1E-82 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 MB46_08840 f56461213dfce821e1379b59115cc5b9 468 SUPERFAMILY SSF53720 1 437 6.81E-118 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 MB46_08840 f56461213dfce821e1379b59115cc5b9 468 Gene3D G3DSA:3.40.605.10 9 430 4.3E-161 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 MB46_08840 f56461213dfce821e1379b59115cc5b9 468 Gene3D G3DSA:3.40.309.10 209 410 4.3E-161 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 MB46_05945 99ed61031af4f8446dacfb6ec255a245 164 SMART SM00881 19 113 2.9E-19 T 14-10-2018 IPR003781 CoA-binding GO:0048037 MB46_05945 99ed61031af4f8446dacfb6ec255a245 164 Pfam PF13380 CoA binding domain 25 139 4.3E-40 T 14-10-2018 IPR003781 CoA-binding GO:0048037 MB46_05945 99ed61031af4f8446dacfb6ec255a245 164 Gene3D G3DSA:3.40.50.720 12 147 8.6E-41 T 14-10-2018 MB46_05945 99ed61031af4f8446dacfb6ec255a245 164 SUPERFAMILY SSF51735 14 142 1.01E-39 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_17590 8cd3e1fde61a5584a3267b6eb90911f6 388 TIGRFAM TIGR02635 RhaI_grampos: L-rhamnose isomerase 9 378 8.9E-193 T 14-10-2018 IPR013457 Rhamnose isomerase-related MB46_17590 8cd3e1fde61a5584a3267b6eb90911f6 388 Gene3D G3DSA:3.20.20.150 2 380 1.0E-127 T 14-10-2018 MB46_17590 8cd3e1fde61a5584a3267b6eb90911f6 388 SUPERFAMILY SSF51658 25 358 2.61E-94 T 14-10-2018 IPR036237 Xylose isomerase-like superfamily MB46_17590 8cd3e1fde61a5584a3267b6eb90911f6 388 Pfam PF06134 L-rhamnose isomerase (RhaA) 92 336 1.4E-5 T 14-10-2018 IPR009308 Rhamnose isomerase GO:0008740|GO:0019299|GO:0030145 KEGG: 00051+5.3.1.14 MB46_17590 8cd3e1fde61a5584a3267b6eb90911f6 388 ProDom PD042532 ISOMERASE L-RHAMNOSE METAL-BINDING METABOLISM RHAMNOSE MANGANESE ENZYME KINASE 3D-STRUCTURE RHAA/RHAB 105 276 9.0E-5 T 14-10-2018 MB46_16460 223918994a444851bc3ea228453427fd 317 Gene3D G3DSA:3.40.50.1360 64 307 7.1E-56 T 14-10-2018 MB46_16460 223918994a444851bc3ea228453427fd 317 Gene3D G3DSA:1.10.10.60 3 53 4.1E-14 T 14-10-2018 MB46_16460 223918994a444851bc3ea228453427fd 317 SUPERFAMILY SSF100950 68 306 1.93E-47 T 14-10-2018 IPR037171 NagB/RpiA transferase-like MB46_16460 223918994a444851bc3ea228453427fd 317 Pfam PF04198 Putative sugar-binding domain 68 305 4.5E-47 T 14-10-2018 IPR007324 Sugar-binding domain, putative GO:0030246 MB46_16375 544e2cd6321b00f5a9701e92cf121178 297 SUPERFAMILY SSF161098 25 297 2.99E-70 T 14-10-2018 IPR035906 MetI-like superfamily MB46_16375 544e2cd6321b00f5a9701e92cf121178 297 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 106 284 4.9E-22 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_16375 544e2cd6321b00f5a9701e92cf121178 297 Gene3D G3DSA:1.10.3720.10 17 288 1.3E-64 T 14-10-2018 IPR035906 MetI-like superfamily MB46_07190 686d69c3692e09db93bcde61d41a7006 398 SUPERFAMILY SSF103473 14 389 3.01E-49 T 14-10-2018 IPR036259 MFS transporter superfamily MB46_07190 686d69c3692e09db93bcde61d41a7006 398 Pfam PF07690 Major Facilitator Superfamily 29 335 2.8E-32 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MB46_07190 686d69c3692e09db93bcde61d41a7006 398 Gene3D G3DSA:1.20.1250.20 22 393 7.5E-45 T 14-10-2018 MB46_10080 450a7a4fa60560e3b392c2e809f6a07e 542 TIGRFAM TIGR02734 crtI_fam: phytoene desaturase 10 523 7.4E-162 T 14-10-2018 IPR014105 Carotenoid/retinoid oxidoreductase GO:0016117|GO:0055114 MB46_10080 450a7a4fa60560e3b392c2e809f6a07e 542 SUPERFAMILY SSF51905 6 507 5.4E-53 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_10080 450a7a4fa60560e3b392c2e809f6a07e 542 Gene3D G3DSA:3.50.50.60 7 93 3.3E-18 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_10080 450a7a4fa60560e3b392c2e809f6a07e 542 Pfam PF01593 Flavin containing amine oxidoreductase 16 504 3.9E-25 T 14-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 MB46_10080 450a7a4fa60560e3b392c2e809f6a07e 542 Gene3D G3DSA:3.50.50.60 208 326 7.3E-12 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_04170 496276fa852df71aec62980a44e6402c 471 PRINTS PR00149 Fumarate lyase superfamily signature 110 128 3.4E-23 T 14-10-2018 IPR000362 Fumarate lyase family MB46_04170 496276fa852df71aec62980a44e6402c 471 PRINTS PR00149 Fumarate lyase superfamily signature 155 173 3.4E-23 T 14-10-2018 IPR000362 Fumarate lyase family MB46_04170 496276fa852df71aec62980a44e6402c 471 PRINTS PR00149 Fumarate lyase superfamily signature 239 266 3.4E-23 T 14-10-2018 IPR000362 Fumarate lyase family MB46_04170 496276fa852df71aec62980a44e6402c 471 PRINTS PR00149 Fumarate lyase superfamily signature 283 299 3.4E-23 T 14-10-2018 IPR000362 Fumarate lyase family MB46_04170 496276fa852df71aec62980a44e6402c 471 SUPERFAMILY SSF48557 13 465 1.34E-129 T 14-10-2018 IPR008948 L-Aspartase-like GO:0003824 MB46_04170 496276fa852df71aec62980a44e6402c 471 Gene3D G3DSA:1.10.275.10 32 237 2.0E-162 T 14-10-2018 IPR024083 Fumarase/histidase, N-terminal MB46_04170 496276fa852df71aec62980a44e6402c 471 Pfam PF14698 Argininosuccinate lyase C-terminal 371 438 1.5E-20 T 14-10-2018 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MB46_04170 496276fa852df71aec62980a44e6402c 471 PRINTS PR00145 Argininosuccinate lyase family signature 283 299 1.6E-50 T 14-10-2018 MB46_04170 496276fa852df71aec62980a44e6402c 471 PRINTS PR00145 Argininosuccinate lyase family signature 109 131 1.6E-50 T 14-10-2018 MB46_04170 496276fa852df71aec62980a44e6402c 471 PRINTS PR00145 Argininosuccinate lyase family signature 318 337 1.6E-50 T 14-10-2018 MB46_04170 496276fa852df71aec62980a44e6402c 471 PRINTS PR00145 Argininosuccinate lyase family signature 150 170 1.6E-50 T 14-10-2018 MB46_04170 496276fa852df71aec62980a44e6402c 471 PRINTS PR00145 Argininosuccinate lyase family signature 201 217 1.6E-50 T 14-10-2018 MB46_04170 496276fa852df71aec62980a44e6402c 471 PRINTS PR00145 Argininosuccinate lyase family signature 239 263 1.6E-50 T 14-10-2018 MB46_04170 496276fa852df71aec62980a44e6402c 471 TIGRFAM TIGR00838 argH: argininosuccinate lyase 10 461 1.1E-173 T 14-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MB46_04170 496276fa852df71aec62980a44e6402c 471 Pfam PF00206 Lyase 19 308 4.3E-58 T 14-10-2018 IPR022761 Fumarate lyase, N-terminal MB46_04170 496276fa852df71aec62980a44e6402c 471 ProSitePatterns PS00163 Fumarate lyases signature. 283 292 - T 14-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 MB46_04170 496276fa852df71aec62980a44e6402c 471 Gene3D G3DSA:1.20.200.10 127 454 2.0E-162 T 14-10-2018 MB46_04170 496276fa852df71aec62980a44e6402c 471 Hamap MF_00006 Argininosuccinate lyase [argH]. 9 461 38.78 T 14-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MB46_04170 496276fa852df71aec62980a44e6402c 471 Gene3D G3DSA:1.10.40.30 368 440 2.0E-162 T 14-10-2018 MB46_17420 39d582fb53e885455dbcb3869af07e18 121 TIGRFAM TIGR03816 tadE_like_DECH: helicase/secretion neighborhood TadE-like protein 5 111 2.2E-23 T 14-10-2018 IPR021202 Apoptosis inhibitor Rv3654c-like MB46_16085 8f9eb474cfa09f3660b78de9b0fb8c56 175 Pfam PF01424 R3H domain 116 172 1.7E-15 T 14-10-2018 IPR001374 R3H domain GO:0003676 MB46_16085 8f9eb474cfa09f3660b78de9b0fb8c56 175 SUPERFAMILY SSF82708 129 172 5.1E-11 T 14-10-2018 IPR036867 R3H domain superfamily GO:0003676 MB46_16085 8f9eb474cfa09f3660b78de9b0fb8c56 175 Gene3D G3DSA:3.30.300.20 25 110 3.9E-15 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta MB46_16085 8f9eb474cfa09f3660b78de9b0fb8c56 175 Gene3D G3DSA:3.30.1370.50 111 175 4.0E-17 T 14-10-2018 IPR036867 R3H domain superfamily GO:0003676 MB46_16085 8f9eb474cfa09f3660b78de9b0fb8c56 175 SMART SM00393 96 174 3.8E-22 T 14-10-2018 IPR001374 R3H domain GO:0003676 MB46_10865 ceb76b79e7a6347bf5b2634835b7404d 71 PRINTS PR00124 ATP synthase C subunit signature 28 43 5.6E-17 T 14-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MB46_10865 ceb76b79e7a6347bf5b2634835b7404d 71 PRINTS PR00124 ATP synthase C subunit signature 45 70 5.6E-17 T 14-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MB46_10865 ceb76b79e7a6347bf5b2634835b7404d 71 PRINTS PR00124 ATP synthase C subunit signature 7 26 5.6E-17 T 14-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MB46_10865 ceb76b79e7a6347bf5b2634835b7404d 71 ProSitePatterns PS00605 ATP synthase c subunit signature. 35 56 - T 14-10-2018 IPR020537 ATP synthase, F0 complex, subunit C, DCCD-binding site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MB46_10865 ceb76b79e7a6347bf5b2634835b7404d 71 SUPERFAMILY SSF81333 8 69 6.15E-16 T 14-10-2018 IPR035921 F/V-ATP synthase subunit C superfamily MB46_10865 ceb76b79e7a6347bf5b2634835b7404d 71 Gene3D G3DSA:1.20.20.10 2 70 7.5E-19 T 14-10-2018 IPR038662 F1F0 ATP synthase subunit C superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MB46_10865 ceb76b79e7a6347bf5b2634835b7404d 71 Hamap MF_01396 ATP synthase subunit c [atpH]. 5 70 14.118 T 14-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MB46_10865 ceb76b79e7a6347bf5b2634835b7404d 71 Pfam PF00137 ATP synthase subunit C 12 68 2.4E-12 T 14-10-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 MB46_16830 28dcb4e9bd47407c3c4d71c6b3db6775 78 Pfam PF00830 Ribosomal L28 family 4 60 5.1E-22 T 14-10-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_16830 28dcb4e9bd47407c3c4d71c6b3db6775 78 Gene3D G3DSA:2.30.170.40 3 78 6.5E-26 T 14-10-2018 IPR037147 Ribosomal protein L28/L24 superfamily GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_16830 28dcb4e9bd47407c3c4d71c6b3db6775 78 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 58 8.0E-23 T 14-10-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MB46_16830 28dcb4e9bd47407c3c4d71c6b3db6775 78 SUPERFAMILY SSF143800 2 77 1.29E-24 T 14-10-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_16830 28dcb4e9bd47407c3c4d71c6b3db6775 78 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 67 18.216 T 14-10-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MB46_07290 659cf5394e6ec536cf365f9e4d947e74 58 Pfam PF05532 CsbD-like 5 57 5.7E-16 T 14-10-2018 IPR008462 CsbD-like domain MB46_07290 659cf5394e6ec536cf365f9e4d947e74 58 SUPERFAMILY SSF69047 5 57 6.93E-7 T 14-10-2018 IPR036629 YjbJ superfamily MB46_11045 4b587dcef05db159ea6987ff7f165a42 361 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 37 321 4.4E-48 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme MB46_11045 4b587dcef05db159ea6987ff7f165a42 361 Gene3D G3DSA:3.40.50.1100 32 327 2.2E-64 T 14-10-2018 MB46_11045 4b587dcef05db159ea6987ff7f165a42 361 Gene3D G3DSA:3.40.50.1100 56 162 2.2E-64 T 14-10-2018 MB46_11045 4b587dcef05db159ea6987ff7f165a42 361 SUPERFAMILY SSF53686 29 340 1.31E-67 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme MB46_16745 f11bdc37097805281a692f106b8777c9 266 Gene3D G3DSA:3.40.50.80 113 266 1.6E-32 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain MB46_16745 f11bdc37097805281a692f106b8777c9 266 Gene3D G3DSA:2.40.30.10 1 104 5.3E-20 T 14-10-2018 MB46_16745 f11bdc37097805281a692f106b8777c9 266 Pfam PF04954 Siderophore-interacting protein 118 262 2.8E-39 T 14-10-2018 IPR007037 Siderophore-interacting protein, C-terminal domain MB46_16745 f11bdc37097805281a692f106b8777c9 266 Pfam PF08021 Siderophore-interacting FAD-binding domain 2 103 3.7E-22 T 14-10-2018 IPR013113 FAD-binding 9, siderophore-interacting MB46_01285 07c1258e62bdbc6845f4629526713c02 335 Pfam PF01261 Xylose isomerase-like TIM barrel 39 250 1.8E-20 T 14-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain MB46_01285 07c1258e62bdbc6845f4629526713c02 335 SUPERFAMILY SSF51658 35 287 4.7E-34 T 14-10-2018 IPR036237 Xylose isomerase-like superfamily MB46_01285 07c1258e62bdbc6845f4629526713c02 335 Gene3D G3DSA:3.20.20.150 2 306 3.2E-79 T 14-10-2018 MB46_17315 3f1decd58a6084cf324e24e09d432927 740 SUPERFAMILY SSF56601 246 706 2.38E-66 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like MB46_17315 3f1decd58a6084cf324e24e09d432927 740 Gene3D G3DSA:3.40.710.10 305 712 1.7E-73 T 14-10-2018 MB46_17315 3f1decd58a6084cf324e24e09d432927 740 SUPERFAMILY SSF53955 67 288 2.39E-66 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily MB46_17315 3f1decd58a6084cf324e24e09d432927 740 Pfam PF00912 Transglycosylase 77 264 3.9E-56 T 14-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MB46_17315 3f1decd58a6084cf324e24e09d432927 740 Pfam PF00905 Penicillin binding protein transpeptidase domain 369 644 1.0E-11 T 14-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 MB46_17315 3f1decd58a6084cf324e24e09d432927 740 Gene3D G3DSA:1.10.3810.10 71 281 3.4E-70 T 14-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MB46_14655 1d550c917b301b4f1a2c26eec87b640f 99 PIRSF PIRSF006909 1 99 6.4E-49 T 14-10-2018 IPR014447 Uncharacterised conserved protein UCP006909 MB46_02115 9ab2950f5ad7c556bcea975f9cec3ed0 248 SMART SM00382 41 232 3.1E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_02115 9ab2950f5ad7c556bcea975f9cec3ed0 248 Pfam PF00005 ABC transporter 32 181 9.0E-31 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_02115 9ab2950f5ad7c556bcea975f9cec3ed0 248 Gene3D G3DSA:3.40.50.300 11 245 7.9E-61 T 14-10-2018 MB46_02115 9ab2950f5ad7c556bcea975f9cec3ed0 248 SUPERFAMILY SSF52540 25 235 1.24E-62 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_02115 9ab2950f5ad7c556bcea975f9cec3ed0 248 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_14350 89772b98bee28dcedface226c6e85dd7 398 Gene3D G3DSA:1.20.1250.20 210 397 1.7E-19 T 14-10-2018 MB46_14350 89772b98bee28dcedface226c6e85dd7 398 Gene3D G3DSA:1.20.1250.20 10 200 1.7E-23 T 14-10-2018 MB46_14350 89772b98bee28dcedface226c6e85dd7 398 Pfam PF07690 Major Facilitator Superfamily 24 356 2.0E-34 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MB46_14350 89772b98bee28dcedface226c6e85dd7 398 SUPERFAMILY SSF103473 13 396 6.8E-51 T 14-10-2018 IPR036259 MFS transporter superfamily MB46_14245 845c3649fc74255e59f4decb8f35e25d 309 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 39 263 8.2E-50 T 14-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 MB46_14245 845c3649fc74255e59f4decb8f35e25d 309 PIRSF PIRSF002936 10 309 5.2E-133 T 14-10-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 MB46_14245 845c3649fc74255e59f4decb8f35e25d 309 TIGRFAM TIGR02039 CysD: sulfate adenylyltransferase, small subunit 18 309 5.0E-134 T 14-10-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 MB46_14245 845c3649fc74255e59f4decb8f35e25d 309 SUPERFAMILY SSF52402 14 217 1.07E-66 T 14-10-2018 MB46_14245 845c3649fc74255e59f4decb8f35e25d 309 Gene3D G3DSA:3.40.50.620 17 219 6.0E-59 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MB46_17835 3ccfbefca9f238e7f015601e01f5bc4c 322 Gene3D G3DSA:1.10.3720.10 80 321 8.5E-71 T 14-10-2018 IPR035906 MetI-like superfamily MB46_17835 3ccfbefca9f238e7f015601e01f5bc4c 322 SUPERFAMILY SSF161098 84 311 7.33E-62 T 14-10-2018 IPR035906 MetI-like superfamily MB46_17835 3ccfbefca9f238e7f015601e01f5bc4c 322 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 116 317 1.3E-18 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_03920 1bec06157f33559a617524dc699cab82 439 SUPERFAMILY SSF53955 367 432 8.75E-8 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily MB46_16735 64ef59c24d2670465633e3efc06fec15 320 Gene3D G3DSA:1.10.3470.10 1 319 6.2E-77 T 14-10-2018 IPR037294 ABC transporter, BtuC-like MB46_16735 64ef59c24d2670465633e3efc06fec15 320 Pfam PF01032 FecCD transport family 9 311 1.7E-68 T 14-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 MB46_16735 64ef59c24d2670465633e3efc06fec15 320 SUPERFAMILY SSF81345 4 311 2.22E-57 T 14-10-2018 IPR037294 ABC transporter, BtuC-like MB46_04920 d27ee4bdc2ac1a6840921a409eb57831 334 Pfam PF02678 Pirin 41 140 1.9E-29 T 14-10-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 MB46_04920 d27ee4bdc2ac1a6840921a409eb57831 334 Gene3D G3DSA:2.60.120.10 35 266 1.3E-64 T 14-10-2018 IPR014710 RmlC-like jelly roll fold MB46_04920 d27ee4bdc2ac1a6840921a409eb57831 334 PIRSF PIRSF006232 20 302 1.4E-75 T 14-10-2018 IPR012093 Pirin Reactome: R-HSA-8935690 MB46_04920 d27ee4bdc2ac1a6840921a409eb57831 334 Pfam PF05726 Pirin C-terminal cupin domain 192 289 4.1E-19 T 14-10-2018 IPR008778 Pirin, C-terminal domain Reactome: R-HSA-8935690 MB46_04920 d27ee4bdc2ac1a6840921a409eb57831 334 SUPERFAMILY SSF51182 40 290 1.6E-68 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily MB46_11055 35ba894e68de5e8d1bd36dc5bd786a83 130 SUPERFAMILY SSF46785 3 126 6.35E-32 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_11055 35ba894e68de5e8d1bd36dc5bd786a83 130 Gene3D G3DSA:3.30.1490.190 80 130 1.3E-24 T 14-10-2018 MB46_11055 35ba894e68de5e8d1bd36dc5bd786a83 130 Pfam PF01475 Ferric uptake regulator family 4 121 6.0E-31 T 14-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 MB46_11055 35ba894e68de5e8d1bd36dc5bd786a83 130 Gene3D G3DSA:1.10.10.10 1 79 1.7E-26 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_18230 ff83f8c8756bac7503edc0a47e1562dc 351 SUPERFAMILY SSF53822 60 331 7.07E-41 T 14-10-2018 IPR028082 Periplasmic binding protein-like I MB46_18230 ff83f8c8756bac7503edc0a47e1562dc 351 Gene3D G3DSA:3.40.50.2300 176 307 1.3E-50 T 14-10-2018 MB46_18230 ff83f8c8756bac7503edc0a47e1562dc 351 Gene3D G3DSA:1.10.260.40 2 56 3.1E-17 T 14-10-2018 MB46_18230 ff83f8c8756bac7503edc0a47e1562dc 351 Gene3D G3DSA:3.40.50.2300 57 323 1.3E-50 T 14-10-2018 MB46_18230 ff83f8c8756bac7503edc0a47e1562dc 351 SUPERFAMILY SSF47413 3 61 1.85E-14 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MB46_18230 ff83f8c8756bac7503edc0a47e1562dc 351 Pfam PF13377 Periplasmic binding protein-like domain 184 337 1.4E-27 T 14-10-2018 MB46_18230 ff83f8c8756bac7503edc0a47e1562dc 351 SMART SM00354 3 73 6.7E-17 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MB46_18230 ff83f8c8756bac7503edc0a47e1562dc 351 Pfam PF00356 Bacterial regulatory proteins, lacI family 5 50 1.4E-9 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MB46_01165 1695ca71db13bc83e54ce6d6a10eb2f4 559 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 204 335 3.7E-30 T 14-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 MB46_01165 1695ca71db13bc83e54ce6d6a10eb2f4 559 SUPERFAMILY SSF52518 380 548 3.04E-38 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold MB46_01165 1695ca71db13bc83e54ce6d6a10eb2f4 559 Gene3D G3DSA:3.40.50.970 7 189 3.4E-49 T 14-10-2018 MB46_01165 1695ca71db13bc83e54ce6d6a10eb2f4 559 SUPERFAMILY SSF52467 168 350 1.25E-34 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily MB46_01165 1695ca71db13bc83e54ce6d6a10eb2f4 559 Gene3D G3DSA:3.40.50.970 375 551 2.3E-41 T 14-10-2018 MB46_01165 1695ca71db13bc83e54ce6d6a10eb2f4 559 SUPERFAMILY SSF52518 12 186 7.36E-41 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold MB46_01165 1695ca71db13bc83e54ce6d6a10eb2f4 559 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 14 182 2.2E-48 T 14-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 MB46_01165 1695ca71db13bc83e54ce6d6a10eb2f4 559 Gene3D G3DSA:3.40.50.1220 200 372 2.4E-41 T 14-10-2018 MB46_01165 1695ca71db13bc83e54ce6d6a10eb2f4 559 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 403 545 1.1E-28 T 14-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 MB46_00245 d75ac3bda464e0f504dd287e7c908532 520 Gene3D G3DSA:2.115.10.20 12 318 5.6E-87 T 14-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily MB46_00245 d75ac3bda464e0f504dd287e7c908532 520 Gene3D G3DSA:2.60.120.200 332 519 8.6E-12 T 14-10-2018 MB46_00245 d75ac3bda464e0f504dd287e7c908532 520 SUPERFAMILY SSF49899 351 516 3.68E-9 T 14-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily MB46_00245 d75ac3bda464e0f504dd287e7c908532 520 Pfam PF04616 Glycosyl hydrolases family 43 13 304 1.0E-76 T 14-10-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 MB46_00245 d75ac3bda464e0f504dd287e7c908532 520 SUPERFAMILY SSF75005 13 312 1.28E-83 T 14-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily MB46_18115 30c395966b41b39b0f454a266cf39cf0 267 Gene3D G3DSA:3.30.530.20 17 159 3.0E-6 T 14-10-2018 IPR023393 START-like domain superfamily MB46_18115 30c395966b41b39b0f454a266cf39cf0 267 SUPERFAMILY SSF55961 15 163 1.16E-11 T 14-10-2018 MB46_16715 f1ca3d4e657b29f23196d533a8b82290 211 SUPERFAMILY SSF51735 3 192 2.18E-33 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_16715 f1ca3d4e657b29f23196d533a8b82290 211 Gene3D G3DSA:3.40.50.720 1 195 1.2E-46 T 14-10-2018 MB46_16715 f1ca3d4e657b29f23196d533a8b82290 211 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 3 93 1.1E-19 T 14-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal MB46_05325 189bae09f319e275b65cdf6512044a2b 301 Gene3D G3DSA:3.10.129.10 38 301 1.0E-63 T 14-10-2018 MB46_05325 189bae09f319e275b65cdf6512044a2b 301 SUPERFAMILY SSF54637 188 278 2.8E-17 T 14-10-2018 IPR029069 HotDog domain superfamily MB46_05325 189bae09f319e275b65cdf6512044a2b 301 Pfam PF01575 MaoC like domain 176 270 7.2E-15 T 14-10-2018 IPR002539 MaoC-like dehydratase domain MB46_05325 189bae09f319e275b65cdf6512044a2b 301 PRINTS PR01483 Fatty acid synthase signature 215 236 1.2E-6 T 14-10-2018 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 MB46_05325 189bae09f319e275b65cdf6512044a2b 301 PRINTS PR01483 Fatty acid synthase signature 193 215 1.2E-6 T 14-10-2018 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 MB46_05325 189bae09f319e275b65cdf6512044a2b 301 SUPERFAMILY SSF54637 57 163 1.31E-7 T 14-10-2018 IPR029069 HotDog domain superfamily MB46_14820 1ab433a7eaecf25d1f445c2b4066cfe0 271 Pfam PF07883 Cupin domain 193 258 6.2E-8 T 14-10-2018 IPR013096 Cupin 2, conserved barrel MB46_14820 1ab433a7eaecf25d1f445c2b4066cfe0 271 Pfam PF07883 Cupin domain 71 140 1.6E-7 T 14-10-2018 IPR013096 Cupin 2, conserved barrel MB46_14820 1ab433a7eaecf25d1f445c2b4066cfe0 271 Gene3D G3DSA:2.60.120.10 39 163 2.7E-98 T 14-10-2018 IPR014710 RmlC-like jelly roll fold MB46_14820 1ab433a7eaecf25d1f445c2b4066cfe0 271 Gene3D G3DSA:2.60.120.10 26 266 2.7E-98 T 14-10-2018 IPR014710 RmlC-like jelly roll fold MB46_14820 1ab433a7eaecf25d1f445c2b4066cfe0 271 TIGRFAM TIGR03214 ura-cupin: putative allantoin catabolism protein 5 270 2.6E-115 T 14-10-2018 IPR017627 Conserved hypothetical protein CHP03214, putative allantoin-urate catabolism protein KEGG: 00230+3.5.3.26|MetaCyc: PWY-5692|MetaCyc: PWY-5698 MB46_14820 1ab433a7eaecf25d1f445c2b4066cfe0 271 SUPERFAMILY SSF51182 19 269 1.3E-75 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily MB46_06400 5e2e19a6245e440f734b968a831f1068 70 Gene3D G3DSA:3.90.820.10 1 70 1.1E-30 T 14-10-2018 MB46_06400 5e2e19a6245e440f734b968a831f1068 70 SUPERFAMILY SSF160582 2 67 4.97E-27 T 14-10-2018 IPR038020 MbtH-like domain superfamily MB46_06400 5e2e19a6245e440f734b968a831f1068 70 SMART SM00923 3 53 2.2E-26 T 14-10-2018 IPR005153 MbtH-like domain MB46_06400 5e2e19a6245e440f734b968a831f1068 70 Pfam PF03621 MbtH-like protein 2 52 8.2E-26 T 14-10-2018 IPR005153 MbtH-like domain MB46_12155 858d67ae4d73b2e6fbf60503bb2e4da2 166 Pfam PF12802 MarR family 54 111 2.2E-12 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MB46_12155 858d67ae4d73b2e6fbf60503bb2e4da2 166 SUPERFAMILY SSF46785 17 159 7.94E-29 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_12155 858d67ae4d73b2e6fbf60503bb2e4da2 166 SMART SM00347 47 148 7.6E-17 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MB46_12155 858d67ae4d73b2e6fbf60503bb2e4da2 166 PRINTS PR00598 Bacterial regulatory protein MarR family signature 138 158 8.8E-12 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MB46_12155 858d67ae4d73b2e6fbf60503bb2e4da2 166 PRINTS PR00598 Bacterial regulatory protein MarR family signature 89 104 8.8E-12 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MB46_12155 858d67ae4d73b2e6fbf60503bb2e4da2 166 PRINTS PR00598 Bacterial regulatory protein MarR family signature 108 124 8.8E-12 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MB46_12155 858d67ae4d73b2e6fbf60503bb2e4da2 166 Gene3D G3DSA:1.10.10.10 3 163 8.0E-32 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_09845 ec482f296f936417ccdbbb08b77c59b4 230 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MB46_09845 ec482f296f936417ccdbbb08b77c59b4 230 SUPERFAMILY SSF51735 3 226 5.15E-47 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_09845 ec482f296f936417ccdbbb08b77c59b4 230 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 71 82 5.6E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_09845 ec482f296f936417ccdbbb08b77c59b4 230 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 5.6E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_09845 ec482f296f936417ccdbbb08b77c59b4 230 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 125 133 5.6E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_09845 ec482f296f936417ccdbbb08b77c59b4 230 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 5.3E-22 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_09845 ec482f296f936417ccdbbb08b77c59b4 230 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 71 82 5.3E-22 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_09845 ec482f296f936417ccdbbb08b77c59b4 230 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 5.3E-22 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_09845 ec482f296f936417ccdbbb08b77c59b4 230 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 119 135 5.3E-22 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_09845 ec482f296f936417ccdbbb08b77c59b4 230 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 5.3E-22 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_09845 ec482f296f936417ccdbbb08b77c59b4 230 Pfam PF00106 short chain dehydrogenase 3 195 6.1E-34 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_09845 ec482f296f936417ccdbbb08b77c59b4 230 Gene3D G3DSA:3.40.50.720 2 230 4.4E-57 T 14-10-2018 MB46_16750 9403c68f22f0cb08747ce792fa175af5 137 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 5 129 1.5E-10 T 14-10-2018 IPR028973 PhnB-like MB46_16750 9403c68f22f0cb08747ce792fa175af5 137 SUPERFAMILY SSF54593 4 132 4.51E-28 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MB46_16750 9403c68f22f0cb08747ce792fa175af5 137 Gene3D G3DSA:3.10.180.10 9 136 3.6E-37 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MB46_12990 a5895861076defca26adc29a4859e355 359 Pfam PF14399 Butirosin biosynthesis protein H, N-terminal 16 151 2.8E-12 T 14-10-2018 IPR026935 Butirosin biosynthesis protein H, N-terminal KEGG: 00524+2.3.2.19|MetaCyc: PWY-7019 MB46_12990 a5895861076defca26adc29a4859e355 359 Pfam PF16169 Domain of unknown function (DUF4872) 163 351 2.0E-16 T 14-10-2018 IPR032369 Domain of unknown function DUF4872 MB46_12260 39a0a959e73f059d036d76a6c76333b0 373 Gene3D G3DSA:3.30.70.1400 52 138 7.0E-89 T 14-10-2018 MB46_12260 39a0a959e73f059d036d76a6c76333b0 373 Gene3D G3DSA:3.30.1360.120 6 240 7.0E-89 T 14-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 MB46_12260 39a0a959e73f059d036d76a6c76333b0 373 SUPERFAMILY SSF101790 292 372 4.09E-24 T 14-10-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal MB46_12260 39a0a959e73f059d036d76a6c76333b0 373 Hamap MF_00259 Aminomethyltransferase [gcvT]. 2 371 41.829 T 14-10-2018 IPR022903 Glycine cleavage system T protein, bacteria GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 MB46_12260 39a0a959e73f059d036d76a6c76333b0 373 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 271 365 5.7E-24 T 14-10-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 MB46_12260 39a0a959e73f059d036d76a6c76333b0 373 PIRSF PIRSF006487 1 373 6.4E-95 T 14-10-2018 IPR028896 Aminomethyltransferase-like KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 MB46_12260 39a0a959e73f059d036d76a6c76333b0 373 Gene3D G3DSA:2.40.30.110 289 371 8.6E-30 T 14-10-2018 MB46_12260 39a0a959e73f059d036d76a6c76333b0 373 Pfam PF01571 Aminomethyltransferase folate-binding domain 8 261 1.6E-91 T 14-10-2018 IPR006222 Aminomethyltransferase, folate-binding domain MB46_12260 39a0a959e73f059d036d76a6c76333b0 373 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 5 371 1.4E-107 T 14-10-2018 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 MB46_12260 39a0a959e73f059d036d76a6c76333b0 373 Gene3D G3DSA:4.10.1250.10 242 283 2.8E-10 T 14-10-2018 MB46_12260 39a0a959e73f059d036d76a6c76333b0 373 SUPERFAMILY SSF103025 5 285 2.04E-92 T 14-10-2018 MB46_07090 153db94e292587cb2b29bcbe37bc1f94 245 SUPERFAMILY SSF51621 1 235 2.39E-78 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 MB46_07090 153db94e292587cb2b29bcbe37bc1f94 245 Gene3D G3DSA:3.20.20.60 1 240 8.2E-87 T 14-10-2018 MB46_07090 153db94e292587cb2b29bcbe37bc1f94 245 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 1 223 4.1E-56 T 14-10-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 MB46_02670 06fced32305200e3fc8ca06f405858ce 235 TIGRFAM TIGR04088 cognate_SipW: SipW-cognate class signal peptide 20 46 2.0E-4 T 14-10-2018 IPR023833 Signal peptide, camelysin MB46_14050 83f6e66604659a0fbb6f93390d890cc0 162 Gene3D G3DSA:3.40.630.30 5 162 7.5E-45 T 14-10-2018 MB46_14050 83f6e66604659a0fbb6f93390d890cc0 162 SUPERFAMILY SSF55729 3 158 2.03E-28 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase MB46_14050 83f6e66604659a0fbb6f93390d890cc0 162 Pfam PF00583 Acetyltransferase (GNAT) family 26 134 7.2E-21 T 14-10-2018 IPR000182 GNAT domain MB46_14210 52cbf8553517e79b75597f9bd81169eb 168 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 33 144 2.5E-6 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MB46_14210 52cbf8553517e79b75597f9bd81169eb 168 SUPERFAMILY SSF54593 26 163 2.82E-26 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MB46_14210 52cbf8553517e79b75597f9bd81169eb 168 Gene3D G3DSA:3.10.180.10 24 158 1.2E-25 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MB46_16955 e2bf72a60de5efc762b77bacad6ffa19 88 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 31 81 1.2E-9 T 14-10-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 MB46_07345 518362120eeac74e6c4d9bfba52d19b7 497 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 179 485 2.0E-106 T 14-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 MB46_07345 518362120eeac74e6c4d9bfba52d19b7 497 Gene3D G3DSA:3.40.220.10 14 168 1.7E-15 T 14-10-2018 MB46_07345 518362120eeac74e6c4d9bfba52d19b7 497 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 341 348 - T 14-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 MB46_07345 518362120eeac74e6c4d9bfba52d19b7 497 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 4 493 30.245 T 14-10-2018 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 MB46_07345 518362120eeac74e6c4d9bfba52d19b7 497 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 49 137 1.1E-7 T 14-10-2018 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 MB46_07345 518362120eeac74e6c4d9bfba52d19b7 497 PRINTS PR00481 Cytosol aminopeptidase signature 255 272 4.6E-43 T 14-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 MB46_07345 518362120eeac74e6c4d9bfba52d19b7 497 PRINTS PR00481 Cytosol aminopeptidase signature 337 357 4.6E-43 T 14-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 MB46_07345 518362120eeac74e6c4d9bfba52d19b7 497 PRINTS PR00481 Cytosol aminopeptidase signature 278 299 4.6E-43 T 14-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 MB46_07345 518362120eeac74e6c4d9bfba52d19b7 497 PRINTS PR00481 Cytosol aminopeptidase signature 365 380 4.6E-43 T 14-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 MB46_07345 518362120eeac74e6c4d9bfba52d19b7 497 PRINTS PR00481 Cytosol aminopeptidase signature 315 336 4.6E-43 T 14-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 MB46_07345 518362120eeac74e6c4d9bfba52d19b7 497 Gene3D G3DSA:3.40.630.10 169 490 3.3E-113 T 14-10-2018 MB46_07345 518362120eeac74e6c4d9bfba52d19b7 497 SUPERFAMILY SSF52949 14 175 3.65E-11 T 14-10-2018 MB46_07345 518362120eeac74e6c4d9bfba52d19b7 497 SUPERFAMILY SSF53187 173 491 1.73E-100 T 14-10-2018 MB46_08630 c8eb607394c6ba7554c8698c3e962d37 233 Gene3D G3DSA:2.40.100.10 74 233 1.9E-26 T 14-10-2018 IPR029000 Cyclophilin-like domain superfamily MB46_08630 c8eb607394c6ba7554c8698c3e962d37 233 SUPERFAMILY SSF50891 84 230 7.45E-25 T 14-10-2018 IPR029000 Cyclophilin-like domain superfamily MB46_08630 c8eb607394c6ba7554c8698c3e962d37 233 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 82 230 1.6E-19 T 14-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 MB46_07525 2ab9b08912795d110e1e8ba4eaa6a6f4 409 Pfam PF02371 Transposase IS116/IS110/IS902 family 284 366 2.3E-19 T 14-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 MB46_07525 2ab9b08912795d110e1e8ba4eaa6a6f4 409 Pfam PF01548 Transposase 22 176 3.6E-43 T 14-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 MB46_08610 e59e813d19672f24902c546dde191ac0 462 Gene3D G3DSA:3.30.465.10 111 447 1.2E-113 T 14-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 MB46_08610 e59e813d19672f24902c546dde191ac0 462 Gene3D G3DSA:3.30.43.10 19 95 3.8E-23 T 14-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 MB46_08610 e59e813d19672f24902c546dde191ac0 462 ProSitePatterns PS00862 Oxygen oxidoreductases covalent FAD-binding site. 44 77 - T 14-10-2018 IPR006093 Oxygen oxidoreductase covalent FAD-binding site GO:0016491|GO:0055114 MB46_08610 e59e813d19672f24902c546dde191ac0 462 SUPERFAMILY SSF55103 190 453 2.58E-6 T 14-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 MB46_08610 e59e813d19672f24902c546dde191ac0 462 Pfam PF08031 Berberine and berberine like 416 459 2.2E-13 T 14-10-2018 IPR012951 Berberine/berberine-like GO:0016491|GO:0050660|GO:0055114 MB46_08610 e59e813d19672f24902c546dde191ac0 462 Pfam PF01565 FAD binding domain 44 178 8.4E-29 T 14-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 MB46_08610 e59e813d19672f24902c546dde191ac0 462 SUPERFAMILY SSF56176 17 210 7.01E-52 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 MB46_08610 e59e813d19672f24902c546dde191ac0 462 Gene3D G3DSA:3.40.462.20 210 420 1.2E-113 T 14-10-2018 MB46_01775 29c29d66ceb22350897e3b2f76196607 265 Pfam PF00795 Carbon-nitrogen hydrolase 2 245 5.7E-39 T 14-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 MB46_01775 29c29d66ceb22350897e3b2f76196607 265 SUPERFAMILY SSF56317 1 261 1.83E-61 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily MB46_01775 29c29d66ceb22350897e3b2f76196607 265 Gene3D G3DSA:3.60.110.10 1 262 1.0E-79 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily MB46_16620 b78b7554f00ac021d91e1969d037247c 233 Gene3D G3DSA:1.20.910.10 15 232 2.0E-60 T 14-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 MB46_16620 b78b7554f00ac021d91e1969d037247c 233 Pfam PF01126 Heme oxygenase 16 220 3.3E-49 T 14-10-2018 IPR016053 Haem oxygenase-like GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|MetaCyc: PWY-5874|Reactome: R-HSA-189483|Reactome: R-HSA-917937 MB46_16620 b78b7554f00ac021d91e1969d037247c 233 PIRSF PIRSF000343 3 233 5.0E-58 T 14-10-2018 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|MetaCyc: PWY-5874|Reactome: R-HSA-189483|Reactome: R-HSA-917937 MB46_16620 b78b7554f00ac021d91e1969d037247c 233 PRINTS PR00088 Haem oxygenase signature 176 197 7.6E-19 T 14-10-2018 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|MetaCyc: PWY-5874|Reactome: R-HSA-189483|Reactome: R-HSA-917937 MB46_16620 b78b7554f00ac021d91e1969d037247c 233 PRINTS PR00088 Haem oxygenase signature 51 76 7.6E-19 T 14-10-2018 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|MetaCyc: PWY-5874|Reactome: R-HSA-189483|Reactome: R-HSA-917937 MB46_16620 b78b7554f00ac021d91e1969d037247c 233 PRINTS PR00088 Haem oxygenase signature 16 41 7.6E-19 T 14-10-2018 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|MetaCyc: PWY-5874|Reactome: R-HSA-189483|Reactome: R-HSA-917937 MB46_16620 b78b7554f00ac021d91e1969d037247c 233 PRINTS PR00088 Haem oxygenase signature 134 155 7.6E-19 T 14-10-2018 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|MetaCyc: PWY-5874|Reactome: R-HSA-189483|Reactome: R-HSA-917937 MB46_16620 b78b7554f00ac021d91e1969d037247c 233 PRINTS PR00088 Haem oxygenase signature 208 226 7.6E-19 T 14-10-2018 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|MetaCyc: PWY-5874|Reactome: R-HSA-189483|Reactome: R-HSA-917937 MB46_16620 b78b7554f00ac021d91e1969d037247c 233 SUPERFAMILY SSF48613 17 224 6.97E-48 T 14-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 MB46_12870 9279c44c49c80f93d86c3218b0abcc10 189 Pfam PF00874 PRD domain 94 179 7.3E-11 T 14-10-2018 IPR011608 PRD domain GO:0006355 MB46_12870 9279c44c49c80f93d86c3218b0abcc10 189 Pfam PF00874 PRD domain 5 70 2.4E-11 T 14-10-2018 IPR011608 PRD domain GO:0006355 MB46_12870 9279c44c49c80f93d86c3218b0abcc10 189 Gene3D G3DSA:1.10.1790.10 77 185 6.8E-21 T 14-10-2018 MB46_12870 9279c44c49c80f93d86c3218b0abcc10 189 SUPERFAMILY SSF63520 81 179 4.05E-16 T 14-10-2018 IPR036634 PRD domain superfamily GO:0006355 MB46_12870 9279c44c49c80f93d86c3218b0abcc10 189 SUPERFAMILY SSF63520 3 73 3.01E-15 T 14-10-2018 IPR036634 PRD domain superfamily GO:0006355 MB46_12870 9279c44c49c80f93d86c3218b0abcc10 189 Gene3D G3DSA:1.10.1790.10 1 74 4.6E-17 T 14-10-2018 MB46_17490 30e17a5453a68ca1bd78559b0d36c77d 203 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 121 200 1.4E-27 T 14-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 MB46_17490 30e17a5453a68ca1bd78559b0d36c77d 203 Pfam PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain 42 113 8.0E-8 T 14-10-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 MB46_17490 30e17a5453a68ca1bd78559b0d36c77d 203 Gene3D G3DSA:3.30.160.70 39 116 2.9E-18 T 14-10-2018 MB46_17490 30e17a5453a68ca1bd78559b0d36c77d 203 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 123 200 8.3E-25 T 14-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 MB46_17490 30e17a5453a68ca1bd78559b0d36c77d 203 SUPERFAMILY SSF46767 121 200 7.46E-25 T 14-10-2018 IPR036217 Methylated DNA-protein cysteine methyltransferase, DNA binding domain Reactome: R-HSA-5657655 MB46_17490 30e17a5453a68ca1bd78559b0d36c77d 203 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 171 177 - T 14-10-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 MB46_17490 30e17a5453a68ca1bd78559b0d36c77d 203 Gene3D G3DSA:1.10.10.10 119 203 6.2E-28 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_17490 30e17a5453a68ca1bd78559b0d36c77d 203 SUPERFAMILY SSF53155 41 117 6.08E-18 T 14-10-2018 IPR036631 Methylated DNA-protein cysteine methyltransferase domain superfamily GO:0003908|GO:0006281 Reactome: R-HSA-5657655 MB46_17490 30e17a5453a68ca1bd78559b0d36c77d 203 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 44 201 35.562 T 14-10-2018 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 MB46_07195 8e5be781b23bc29d966eac6c67b9592a 199 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 58 4.2E-12 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MB46_07195 8e5be781b23bc29d966eac6c67b9592a 199 SUPERFAMILY SSF46689 4 72 1.08E-14 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MB46_07195 8e5be781b23bc29d966eac6c67b9592a 199 SUPERFAMILY SSF48498 81 195 3.42E-19 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily MB46_07195 8e5be781b23bc29d966eac6c67b9592a 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 13 26 2.9E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MB46_07195 8e5be781b23bc29d966eac6c67b9592a 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 57 2.9E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MB46_07195 8e5be781b23bc29d966eac6c67b9592a 199 ProSitePatterns PS01081 TetR-type HTH domain signature. 25 55 - T 14-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site MB46_07195 8e5be781b23bc29d966eac6c67b9592a 199 Gene3D G3DSA:1.10.10.60 1 67 9.6E-25 T 14-10-2018 MB46_07195 8e5be781b23bc29d966eac6c67b9592a 199 Gene3D G3DSA:1.10.357.10 76 197 1.8E-19 T 14-10-2018 MB46_02560 751de4da9762fc0e059790e53c9954b0 437 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 1 417 6.4E-125 T 14-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 MB46_02560 751de4da9762fc0e059790e53c9954b0 437 SUPERFAMILY SSF48179 202 300 2.38E-27 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MB46_02560 751de4da9762fc0e059790e53c9954b0 437 PIRSF PIRSF500134 1 437 9.2E-148 T 14-10-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 MB46_02560 751de4da9762fc0e059790e53c9954b0 437 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 321 421 5.6E-27 T 14-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 MB46_02560 751de4da9762fc0e059790e53c9954b0 437 Gene3D G3DSA:1.20.5.100 202 231 1.2E-12 T 14-10-2018 MB46_02560 751de4da9762fc0e059790e53c9954b0 437 PIRSF PIRSF000124 1 436 1.0E-118 T 14-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 MB46_02560 751de4da9762fc0e059790e53c9954b0 437 Gene3D G3DSA:3.40.50.720 1 198 1.2E-65 T 14-10-2018 MB46_02560 751de4da9762fc0e059790e53c9954b0 437 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 203 296 1.2E-31 T 14-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 MB46_02560 751de4da9762fc0e059790e53c9954b0 437 SUPERFAMILY SSF52413 313 431 3.4E-32 T 14-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 MB46_02560 751de4da9762fc0e059790e53c9954b0 437 SMART SM00984 320 421 6.4E-40 T 14-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 MB46_02560 751de4da9762fc0e059790e53c9954b0 437 Gene3D G3DSA:3.40.50.720 233 437 1.1E-63 T 14-10-2018 MB46_02560 751de4da9762fc0e059790e53c9954b0 437 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 1 175 2.7E-57 T 14-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 MB46_02560 751de4da9762fc0e059790e53c9954b0 437 SUPERFAMILY SSF51735 1 187 2.24E-47 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_09200 67eaf1482e7f6ecb861782ffb3d2e0ff 265 PIRSF PIRSF006157 3 265 1.4E-79 T 14-10-2018 IPR014436 Extradiol aromatic ring-opening dioxygenase, DODA-type GO:0008270|GO:0016701|GO:0055114 MB46_09200 67eaf1482e7f6ecb861782ffb3d2e0ff 265 SUPERFAMILY SSF53213 9 258 8.37E-76 T 14-10-2018 MB46_09200 67eaf1482e7f6ecb861782ffb3d2e0ff 265 Gene3D G3DSA:3.40.830.10 2 253 4.3E-73 T 14-10-2018 MB46_09200 67eaf1482e7f6ecb861782ffb3d2e0ff 265 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 27 240 9.7E-39 T 14-10-2018 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 MB46_02575 13fd0977260de41a7c5cebc318f45df9 322 Hamap MF_00956 GDP-L-fucose synthase [fcl]. 13 315 47.831 T 14-10-2018 IPR028614 GDP-L-fucose synthase/GDP-L-colitose synthase GO:0009226|GO:0016491 KEGG: 00051+1.1.1.271|KEGG: 00520+1.1.1.271|MetaCyc: PWY-66|Reactome: R-HSA-6787639 MB46_02575 13fd0977260de41a7c5cebc318f45df9 322 SUPERFAMILY SSF51735 14 317 7.74E-68 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_02575 13fd0977260de41a7c5cebc318f45df9 322 Pfam PF01370 NAD dependent epimerase/dehydratase family 17 247 3.0E-71 T 14-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 MB46_02575 13fd0977260de41a7c5cebc318f45df9 322 Gene3D G3DSA:3.40.50.720 17 304 3.3E-100 T 14-10-2018 MB46_02575 13fd0977260de41a7c5cebc318f45df9 322 Gene3D G3DSA:3.90.25.10 178 313 3.3E-100 T 14-10-2018 MB46_19070 2497eeb0f8ab8183e537fd2e8862f2b1 259 TIGRFAM TIGR00453 ispD: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 11 248 7.4E-58 T 14-10-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 MB46_19070 2497eeb0f8ab8183e537fd2e8862f2b1 259 Gene3D G3DSA:3.90.550.10 2 250 2.3E-64 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MB46_19070 2497eeb0f8ab8183e537fd2e8862f2b1 259 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 10 248 4.3E-54 T 14-10-2018 IPR034683 Cytidylyltransferase IspD/TarI GO:0070567 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 MB46_19070 2497eeb0f8ab8183e537fd2e8862f2b1 259 ProSitePatterns PS01295 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. 111 118 - T 14-10-2018 IPR018294 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site GO:0003824|GO:0008299 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 MB46_19070 2497eeb0f8ab8183e537fd2e8862f2b1 259 SUPERFAMILY SSF53448 9 248 1.08E-47 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MB46_19070 2497eeb0f8ab8183e537fd2e8862f2b1 259 Hamap MF_00108 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [ispD]. 8 248 35.81 T 14-10-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 MB46_12860 34099a0fb9950635408a5050be97e8b4 291 Gene3D G3DSA:3.40.1190.20 2 290 7.7E-54 T 14-10-2018 IPR029056 Ribokinase-like MB46_12860 34099a0fb9950635408a5050be97e8b4 291 Pfam PF00294 pfkB family carbohydrate kinase 5 288 6.5E-36 T 14-10-2018 IPR011611 Carbohydrate kinase PfkB MB46_12860 34099a0fb9950635408a5050be97e8b4 291 SUPERFAMILY SSF53613 4 289 4.83E-51 T 14-10-2018 IPR029056 Ribokinase-like MB46_06160 8db126bd8fd346bd9480f8ac58b0d552 291 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 122 139 - T 14-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 MB46_06160 8db126bd8fd346bd9480f8ac58b0d552 291 Pfam PF00248 Aldo/keto reductase family 22 266 9.7E-43 T 14-10-2018 IPR023210 NADP-dependent oxidoreductase domain MB46_06160 8db126bd8fd346bd9480f8ac58b0d552 291 PRINTS PR00069 Aldo-keto reductase signature 202 226 2.3E-44 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MB46_06160 8db126bd8fd346bd9480f8ac58b0d552 291 PRINTS PR00069 Aldo-keto reductase signature 33 57 2.3E-44 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MB46_06160 8db126bd8fd346bd9480f8ac58b0d552 291 PRINTS PR00069 Aldo-keto reductase signature 89 107 2.3E-44 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MB46_06160 8db126bd8fd346bd9480f8ac58b0d552 291 PRINTS PR00069 Aldo-keto reductase signature 156 185 2.3E-44 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MB46_06160 8db126bd8fd346bd9480f8ac58b0d552 291 PRINTS PR00069 Aldo-keto reductase signature 122 139 2.3E-44 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MB46_06160 8db126bd8fd346bd9480f8ac58b0d552 291 PIRSF PIRSF000097 1 277 5.5E-80 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MB46_06160 8db126bd8fd346bd9480f8ac58b0d552 291 SUPERFAMILY SSF51430 3 272 1.7E-82 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily MB46_06160 8db126bd8fd346bd9480f8ac58b0d552 291 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 37 54 - T 14-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 MB46_06160 8db126bd8fd346bd9480f8ac58b0d552 291 Gene3D G3DSA:3.20.20.100 1 278 6.5E-102 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily MB46_04865 df2539dd1a0d0ed6d0e47d921089b2ef 407 SUPERFAMILY SSF51569 58 344 1.22E-7 T 14-10-2018 MB46_04865 df2539dd1a0d0ed6d0e47d921089b2ef 407 Pfam PF06187 Protein of unknown function (DUF993) 6 397 1.1E-172 T 14-10-2018 IPR009334 Protein of unknown function DUF993 MB46_04865 df2539dd1a0d0ed6d0e47d921089b2ef 407 Gene3D G3DSA:3.20.20.500 1 393 1.6E-165 T 14-10-2018 MB46_16410 eb78b63920a5ef7d30197c7f36984038 96 Pfam PF02597 ThiS family 7 96 3.9E-12 T 14-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 MB46_16410 eb78b63920a5ef7d30197c7f36984038 96 Gene3D G3DSA:3.10.20.30 4 96 1.2E-23 T 14-10-2018 IPR012675 Beta-grasp domain superfamily MB46_16410 eb78b63920a5ef7d30197c7f36984038 96 SUPERFAMILY SSF54285 4 96 3.92E-16 T 14-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp MB46_00990 13421642c22521e7a1d1e0786b26e065 269 Pfam PF01551 Peptidase family M23 170 265 1.9E-31 T 14-10-2018 IPR016047 Peptidase M23 MB46_00990 13421642c22521e7a1d1e0786b26e065 269 Gene3D G3DSA:2.70.70.10 120 269 3.2E-46 T 14-10-2018 IPR011055 Duplicated hybrid motif MB46_00990 13421642c22521e7a1d1e0786b26e065 269 SUPERFAMILY SSF51261 131 269 3.92E-52 T 14-10-2018 IPR011055 Duplicated hybrid motif MB46_12065 847a98771f901e691f7c967d735a5826 328 Gene3D G3DSA:3.40.50.720 23 326 2.0E-70 T 14-10-2018 MB46_12065 847a98771f901e691f7c967d735a5826 328 Pfam PF00106 short chain dehydrogenase 37 235 1.1E-24 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_12065 847a98771f901e691f7c967d735a5826 328 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 37 54 4.8E-14 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_12065 847a98771f901e691f7c967d735a5826 328 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 229 4.8E-14 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_12065 847a98771f901e691f7c967d735a5826 328 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 169 4.8E-14 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_12065 847a98771f901e691f7c967d735a5826 328 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 109 120 4.8E-14 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_12065 847a98771f901e691f7c967d735a5826 328 SUPERFAMILY SSF51735 33 286 7.41E-47 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_02435 0452ad6ea9f1780b9df1a185536bf45a 274 Gene3D G3DSA:3.40.960.10 144 271 3.2E-5 T 14-10-2018 MB46_05030 41ecc3dafe53a90bb5accc3ca4b9c6d2 222 SMART SM00563 35 154 1.0E-30 T 14-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 MB46_05030 41ecc3dafe53a90bb5accc3ca4b9c6d2 222 SUPERFAMILY SSF69593 15 216 2.88E-43 T 14-10-2018 MB46_05030 41ecc3dafe53a90bb5accc3ca4b9c6d2 222 Pfam PF01553 Acyltransferase 21 151 3.1E-23 T 14-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 MB46_10630 ebd196fb22341f28921fb5c6e52f00b7 274 Pfam PF00005 ABC transporter 33 180 4.9E-29 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_10630 ebd196fb22341f28921fb5c6e52f00b7 274 Gene3D G3DSA:3.40.50.300 11 263 4.0E-62 T 14-10-2018 MB46_10630 ebd196fb22341f28921fb5c6e52f00b7 274 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_10630 ebd196fb22341f28921fb5c6e52f00b7 274 SMART SM00382 41 229 4.6E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_10630 ebd196fb22341f28921fb5c6e52f00b7 274 SUPERFAMILY SSF52540 9 243 1.25E-56 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_08775 f344201ba0bc90efffe42a7e7e7ef8a6 279 SUPERFAMILY SSF54637 159 274 6.92E-8 T 14-10-2018 IPR029069 HotDog domain superfamily MB46_08775 f344201ba0bc90efffe42a7e7e7ef8a6 279 Gene3D G3DSA:3.10.129.90 24 273 3.9E-16 T 14-10-2018 MB46_08775 f344201ba0bc90efffe42a7e7e7ef8a6 279 Pfam PF13622 Thioesterase-like superfamily 38 271 8.9E-35 T 14-10-2018 MB46_16080 6806443625f1218fafffa11ac2bf11d8 212 SUPERFAMILY SSF53335 18 190 1.91E-25 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MB46_16080 6806443625f1218fafffa11ac2bf11d8 212 Gene3D G3DSA:3.40.50.150 3 212 4.0E-51 T 14-10-2018 MB46_16080 6806443625f1218fafffa11ac2bf11d8 212 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 25 184 1.1E-38 T 14-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 MB46_16080 6806443625f1218fafffa11ac2bf11d8 212 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 12 191 22.739 T 14-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 MB46_16080 6806443625f1218fafffa11ac2bf11d8 212 Pfam PF02527 rRNA small subunit methyltransferase G 21 193 5.7E-49 T 14-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 MB46_13135 a6dbbb80f1c9225d470d1e69679f0c5b 363 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 6 358 59.154 T 14-10-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 MB46_13135 a6dbbb80f1c9225d470d1e69679f0c5b 363 Pfam PF00814 Glycoprotease family 28 332 4.3E-90 T 14-10-2018 IPR000905 Gcp-like domain MB46_13135 a6dbbb80f1c9225d470d1e69679f0c5b 363 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 143 155 2.2E-29 T 14-10-2018 IPR017861 Kae1/TsaD family MB46_13135 a6dbbb80f1c9225d470d1e69679f0c5b 363 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 9 22 2.2E-29 T 14-10-2018 IPR017861 Kae1/TsaD family MB46_13135 a6dbbb80f1c9225d470d1e69679f0c5b 363 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 167 188 2.2E-29 T 14-10-2018 IPR017861 Kae1/TsaD family MB46_13135 a6dbbb80f1c9225d470d1e69679f0c5b 363 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 289 298 2.2E-29 T 14-10-2018 IPR017861 Kae1/TsaD family MB46_13135 a6dbbb80f1c9225d470d1e69679f0c5b 363 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 9 332 1.4E-96 T 14-10-2018 IPR017861 Kae1/TsaD family MB46_13135 a6dbbb80f1c9225d470d1e69679f0c5b 363 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 8 338 1.4E-121 T 14-10-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 MB46_13135 a6dbbb80f1c9225d470d1e69679f0c5b 363 SUPERFAMILY SSF53067 7 334 4.96E-36 T 14-10-2018 MB46_13135 a6dbbb80f1c9225d470d1e69679f0c5b 363 Gene3D G3DSA:3.30.420.40 141 319 2.3E-110 T 14-10-2018 MB46_13135 a6dbbb80f1c9225d470d1e69679f0c5b 363 Gene3D G3DSA:3.30.420.40 8 339 2.3E-110 T 14-10-2018 MB46_14855 a2626980b2a4267487a0eb08d67d547f 120 SUPERFAMILY SSF51230 4 84 1.24E-25 T 14-10-2018 IPR011053 Single hybrid motif MB46_14855 a2626980b2a4267487a0eb08d67d547f 120 Gene3D G3DSA:2.40.50.100 2 86 8.9E-26 T 14-10-2018 MB46_14855 a2626980b2a4267487a0eb08d67d547f 120 Pfam PF00364 Biotin-requiring enzyme 5 76 2.8E-20 T 14-10-2018 IPR000089 Biotin/lipoyl attachment MB46_14855 a2626980b2a4267487a0eb08d67d547f 120 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 14-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 MB46_02370 80324d4fa33be9d35f0ffe53bc5a50db 288 Gene3D G3DSA:3.40.50.1110 23 212 6.1E-27 T 14-10-2018 IPR036514 SGNH hydrolase superfamily MB46_02370 80324d4fa33be9d35f0ffe53bc5a50db 288 SUPERFAMILY SSF52266 20 210 8.49E-36 T 14-10-2018 MB46_02370 80324d4fa33be9d35f0ffe53bc5a50db 288 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 27 201 3.6E-23 T 14-10-2018 IPR013830 SGNH hydrolase-type esterase domain MB46_09425 0254daff38367a088fe17dd8a89374a8 452 Gene3D G3DSA:1.20.1250.20 26 451 2.5E-57 T 14-10-2018 MB46_09425 0254daff38367a088fe17dd8a89374a8 452 Pfam PF00083 Sugar (and other) transporter 30 237 3.8E-25 T 14-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 MB46_09425 0254daff38367a088fe17dd8a89374a8 452 ProSitePatterns PS00217 Sugar transport proteins signature 2. 139 164 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MB46_09425 0254daff38367a088fe17dd8a89374a8 452 SUPERFAMILY SSF103473 20 446 3.92E-54 T 14-10-2018 IPR036259 MFS transporter superfamily MB46_16540 31ef9d614b60641143a50f72cf03b985 480 Pfam PF08328 Adenylosuccinate lyase C-terminal 348 468 1.1E-43 T 14-10-2018 IPR013539 Adenylosuccinate lyase PurB, C-terminal GO:0004018|GO:0006188 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234 MB46_16540 31ef9d614b60641143a50f72cf03b985 480 SUPERFAMILY SSF48557 29 477 5.03E-90 T 14-10-2018 IPR008948 L-Aspartase-like GO:0003824 MB46_16540 31ef9d614b60641143a50f72cf03b985 480 Gene3D G3DSA:1.20.200.10 135 469 1.1E-137 T 14-10-2018 MB46_16540 31ef9d614b60641143a50f72cf03b985 480 Gene3D G3DSA:1.10.275.10 10 134 2.2E-34 T 14-10-2018 IPR024083 Fumarase/histidase, N-terminal MB46_16540 31ef9d614b60641143a50f72cf03b985 480 ProSitePatterns PS00163 Fumarate lyases signature. 311 320 - T 14-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 MB46_16540 31ef9d614b60641143a50f72cf03b985 480 PRINTS PR00149 Fumarate lyase superfamily signature 311 327 3.0E-16 T 14-10-2018 IPR000362 Fumarate lyase family MB46_16540 31ef9d614b60641143a50f72cf03b985 480 PRINTS PR00149 Fumarate lyase superfamily signature 134 152 3.0E-16 T 14-10-2018 IPR000362 Fumarate lyase family MB46_16540 31ef9d614b60641143a50f72cf03b985 480 PRINTS PR00149 Fumarate lyase superfamily signature 180 198 3.0E-16 T 14-10-2018 IPR000362 Fumarate lyase family MB46_16540 31ef9d614b60641143a50f72cf03b985 480 PRINTS PR00149 Fumarate lyase superfamily signature 268 295 3.0E-16 T 14-10-2018 IPR000362 Fumarate lyase family MB46_16540 31ef9d614b60641143a50f72cf03b985 480 Pfam PF00206 Lyase 32 327 2.1E-49 T 14-10-2018 IPR022761 Fumarate lyase, N-terminal MB46_16540 31ef9d614b60641143a50f72cf03b985 480 Gene3D G3DSA:1.10.40.30 399 468 1.1E-137 T 14-10-2018 MB46_04320 6fc2a6ab3057a34ca5bb243be778d254 464 TIGRFAM TIGR00791 gntP: transporter, gluconate:H+ symporter (GntP) family 16 462 1.2E-111 T 14-10-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 MB46_04320 6fc2a6ab3057a34ca5bb243be778d254 464 PIRSF PIRSF002746 10 464 2.8E-146 T 14-10-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 MB46_04320 6fc2a6ab3057a34ca5bb243be778d254 464 Pfam PF02447 GntP family permease 16 463 3.8E-124 T 14-10-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 MB46_08855 c6a5ac5d8cceec1063c4dd02f9768060 251 SUPERFAMILY SSF48452 80 156 1.71E-5 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MB46_08855 c6a5ac5d8cceec1063c4dd02f9768060 251 Gene3D G3DSA:1.25.40.10 77 190 1.8E-6 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MB46_16290 f07ba129c6d4f8f17dfa3c2f266bc1a5 485 Pfam PF11855 Protein of unknown function (DUF3375) 16 479 2.7E-97 T 14-10-2018 IPR021804 Protein of unknown function DUF3375 MB46_18525 e2efbb3f80a0a9afe2cc61bed6946fdc 1606 SMART SM00490 350 436 2.9E-13 T 14-10-2018 IPR001650 Helicase, C-terminal MB46_18525 e2efbb3f80a0a9afe2cc61bed6946fdc 1606 SUPERFAMILY SSF52540 31 439 2.78E-45 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_18525 e2efbb3f80a0a9afe2cc61bed6946fdc 1606 Gene3D G3DSA:3.40.50.300 2 240 1.4E-52 T 14-10-2018 MB46_18525 e2efbb3f80a0a9afe2cc61bed6946fdc 1606 Pfam PF00271 Helicase conserved C-terminal domain 370 436 1.3E-11 T 14-10-2018 IPR001650 Helicase, C-terminal MB46_18525 e2efbb3f80a0a9afe2cc61bed6946fdc 1606 Gene3D G3DSA:3.40.50.300 277 454 1.2E-25 T 14-10-2018 MB46_18525 e2efbb3f80a0a9afe2cc61bed6946fdc 1606 SMART SM00487 15 248 1.8E-30 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MB46_18525 e2efbb3f80a0a9afe2cc61bed6946fdc 1606 Pfam PF08494 DEAD/H associated 707 895 7.0E-76 T 14-10-2018 IPR013701 DEAD/H associated GO:0005524|GO:0016818 MB46_18525 e2efbb3f80a0a9afe2cc61bed6946fdc 1606 Pfam PF06224 Winged helix DNA-binding domain 953 1140 9.4E-8 T 14-10-2018 IPR009351 Protein of unknown function DUF1006 MB46_18525 e2efbb3f80a0a9afe2cc61bed6946fdc 1606 Pfam PF00270 DEAD/DEAH box helicase 20 221 9.5E-24 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MB46_12755 bf2b320d2411a98eee5666e3d95f896e 222 SUPERFAMILY SSF46689 9 79 2.51E-15 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MB46_12755 bf2b320d2411a98eee5666e3d95f896e 222 ProSitePatterns PS01081 TetR-type HTH domain signature. 26 55 - T 14-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site MB46_12755 bf2b320d2411a98eee5666e3d95f896e 222 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 2.2E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MB46_12755 bf2b320d2411a98eee5666e3d95f896e 222 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 57 2.2E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MB46_12755 bf2b320d2411a98eee5666e3d95f896e 222 Gene3D G3DSA:1.10.357.10 4 216 1.1E-57 T 14-10-2018 MB46_12755 bf2b320d2411a98eee5666e3d95f896e 222 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 58 8.2E-12 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MB46_11645 a89ff5987b06c36a7bcc8fa30e710f50 224 Pfam PF00072 Response regulator receiver domain 5 114 1.9E-30 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MB46_11645 a89ff5987b06c36a7bcc8fa30e710f50 224 SMART SM00448 3 113 1.8E-46 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MB46_11645 a89ff5987b06c36a7bcc8fa30e710f50 224 Gene3D G3DSA:3.40.50.2300 1 121 2.6E-40 T 14-10-2018 MB46_11645 a89ff5987b06c36a7bcc8fa30e710f50 224 Gene3D G3DSA:1.10.10.10 123 224 1.6E-36 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_11645 a89ff5987b06c36a7bcc8fa30e710f50 224 SMART SM00862 146 222 2.0E-22 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MB46_11645 a89ff5987b06c36a7bcc8fa30e710f50 224 SUPERFAMILY SSF52172 3 176 8.97E-44 T 14-10-2018 IPR011006 CheY-like superfamily MB46_11645 a89ff5987b06c36a7bcc8fa30e710f50 224 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 221 1.2E-25 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MB46_12135 1e947ec0afab7cf163c2d0dad52eb776 507 TIGRFAM TIGR02121 Na_Pro_sym: sodium/proline symporter 8 492 3.4E-197 T 14-10-2018 IPR011851 Sodium/proline symporter GO:0005298|GO:0006814|GO:0015824|GO:0016021|GO:0031402 MB46_12135 1e947ec0afab7cf163c2d0dad52eb776 507 Pfam PF00474 Sodium:solute symporter family 35 439 4.0E-101 T 14-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 MB46_12135 1e947ec0afab7cf163c2d0dad52eb776 507 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 35 439 6.5E-88 T 14-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 MB46_12135 1e947ec0afab7cf163c2d0dad52eb776 507 Gene3D G3DSA:1.20.1730.10 11 504 6.1E-93 T 14-10-2018 IPR038377 Sodium/glucose symporter superfamily MB46_11765 df3831bf9ae613afb24b7f24031ce3ce 320 Gene3D G3DSA:1.10.287.110 2 77 3.7E-21 T 14-10-2018 IPR036869 Chaperone J-domain superfamily MB46_11765 df3831bf9ae613afb24b7f24031ce3ce 320 ProSitePatterns PS00636 Nt-dnaJ domain signature. 45 64 - T 14-10-2018 IPR018253 DnaJ domain, conserved site MB46_11765 df3831bf9ae613afb24b7f24031ce3ce 320 SMART SM00271 6 60 1.6E-17 T 14-10-2018 IPR001623 DnaJ domain MB46_11765 df3831bf9ae613afb24b7f24031ce3ce 320 PRINTS PR00625 DnaJ domain signature 40 60 6.0E-9 T 14-10-2018 IPR001623 DnaJ domain MB46_11765 df3831bf9ae613afb24b7f24031ce3ce 320 PRINTS PR00625 DnaJ domain signature 9 27 6.0E-9 T 14-10-2018 IPR001623 DnaJ domain MB46_11765 df3831bf9ae613afb24b7f24031ce3ce 320 Pfam PF00226 DnaJ domain 7 65 1.6E-17 T 14-10-2018 IPR001623 DnaJ domain MB46_11765 df3831bf9ae613afb24b7f24031ce3ce 320 SUPERFAMILY SSF46565 5 72 4.58E-23 T 14-10-2018 IPR036869 Chaperone J-domain superfamily MB46_09510 c68f2c157295956f762d3167978a09bd 517 SUPERFAMILY SSF52540 199 511 5.97E-37 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_09510 c68f2c157295956f762d3167978a09bd 517 Gene3D G3DSA:3.30.230.10 2 166 5.0E-10 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MB46_09510 c68f2c157295956f762d3167978a09bd 517 Pfam PF01078 Magnesium chelatase, subunit ChlI 201 407 1.8E-87 T 14-10-2018 IPR000523 Magnesium chelatase ChlI domain MB46_09510 c68f2c157295956f762d3167978a09bd 517 TIGRFAM TIGR00368 TIGR00368: Mg chelatase-like protein 10 496 1.0E-137 T 14-10-2018 IPR004482 Mg chelatase-related protein MB46_09510 c68f2c157295956f762d3167978a09bd 517 SMART SM00382 221 405 1.5E-7 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_09510 c68f2c157295956f762d3167978a09bd 517 Pfam PF13335 Magnesium chelatase, subunit ChlI C-terminal 416 511 1.1E-21 T 14-10-2018 IPR025158 Mg chelatase-related protein, C-terminal domain MB46_09510 c68f2c157295956f762d3167978a09bd 517 Pfam PF13541 Subunit ChlI of Mg-chelatase 21 141 8.4E-34 T 14-10-2018 MB46_09510 c68f2c157295956f762d3167978a09bd 517 Gene3D G3DSA:3.40.50.300 201 514 4.2E-40 T 14-10-2018 MB46_09510 c68f2c157295956f762d3167978a09bd 517 SUPERFAMILY SSF54211 2 162 1.37E-28 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MB46_17285 b579b32fa8881f64dc59bcd1404232cc 327 Pfam PF01259 SAICAR synthetase 17 295 3.2E-94 T 14-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MB46_17285 b579b32fa8881f64dc59bcd1404232cc 327 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 14 323 23.544 T 14-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MB46_17285 b579b32fa8881f64dc59bcd1404232cc 327 SUPERFAMILY SSF56104 10 326 1.5E-91 T 14-10-2018 MB46_17285 b579b32fa8881f64dc59bcd1404232cc 327 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 16 323 1.5E-64 T 14-10-2018 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 MB46_17285 b579b32fa8881f64dc59bcd1404232cc 327 Gene3D G3DSA:3.30.470.20 130 275 3.0E-55 T 14-10-2018 MB46_15960 e71f527df8c4d916342586a7a6c7a224 436 Pfam PF13796 Putative sensor 30 216 2.9E-28 T 14-10-2018 IPR025828 Putative sensor domain MB46_15960 e71f527df8c4d916342586a7a6c7a224 436 SUPERFAMILY SSF55874 317 434 2.56E-10 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MB46_15960 e71f527df8c4d916342586a7a6c7a224 436 Pfam PF07730 Histidine kinase 247 310 1.7E-12 T 14-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 MB46_15960 e71f527df8c4d916342586a7a6c7a224 436 Gene3D G3DSA:3.30.565.10 312 435 1.1E-20 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MB46_05330 9720cf820140ffb0f1e1ef9aa10877aa 259 ProDom PD120223 SCO3432 GENE ML2604 GP79 GP77 CGL2230 MB0190 36 223 2.0E-6 T 14-10-2018 MB46_05330 9720cf820140ffb0f1e1ef9aa10877aa 259 Pfam PF10979 Protein of unknown function (DUF2786) 20 57 1.9E-13 T 14-10-2018 IPR024498 Domain of unknown function DUF2786 MB46_00420 af870f090ceda20eeac2d6df48f35552 490 Pfam PF00251 Glycosyl hydrolases family 32 N-terminal domain 9 288 7.2E-27 T 14-10-2018 IPR013148 Glycosyl hydrolase family 32, N-terminal MB46_00420 af870f090ceda20eeac2d6df48f35552 490 Gene3D G3DSA:2.115.10.20 2 313 6.8E-52 T 14-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily MB46_00420 af870f090ceda20eeac2d6df48f35552 490 Gene3D G3DSA:2.60.120.560 314 468 2.2E-11 T 14-10-2018 MB46_00420 af870f090ceda20eeac2d6df48f35552 490 SUPERFAMILY SSF75005 8 295 3.28E-52 T 14-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily MB46_00420 af870f090ceda20eeac2d6df48f35552 490 Pfam PF08244 Glycosyl hydrolases family 32 C terminal 331 468 1.3E-7 T 14-10-2018 IPR013189 Glycosyl hydrolase family 32, C-terminal MB46_00420 af870f090ceda20eeac2d6df48f35552 490 SMART SM00640 19 428 1.5E-9 T 14-10-2018 IPR001362 Glycoside hydrolase, family 32 GO:0004553|GO:0005975 MB46_12880 1ca2773ebe36ccb28c1da2f0cd24d524 515 Gene3D G3DSA:3.30.1360.60 434 512 2.9E-25 T 14-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 MB46_12880 1ca2773ebe36ccb28c1da2f0cd24d524 515 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 436 497 1.3E-16 T 14-10-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 MB46_12880 1ca2773ebe36ccb28c1da2f0cd24d524 515 Pfam PF00367 phosphotransferase system, EIIB 441 473 1.4E-13 T 14-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 MB46_12880 1ca2773ebe36ccb28c1da2f0cd24d524 515 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 451 468 - T 14-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 MB46_12880 1ca2773ebe36ccb28c1da2f0cd24d524 515 SUPERFAMILY SSF55604 439 512 2.62E-19 T 14-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 MB46_12880 1ca2773ebe36ccb28c1da2f0cd24d524 515 Pfam PF02378 Phosphotransferase system, EIIC 9 332 1.0E-74 T 14-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 MB46_18080 c4e03e7c2b65503764073a61d3cd973d 168 Gene3D G3DSA:3.30.720.110 78 139 4.4E-9 T 14-10-2018 MB46_18080 c4e03e7c2b65503764073a61d3cd973d 168 SUPERFAMILY SSF54593 14 128 6.85E-20 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MB46_18080 c4e03e7c2b65503764073a61d3cd973d 168 Gene3D G3DSA:3.30.720.120 12 77 1.2E-5 T 14-10-2018 MB46_00500 2302c643dff6c06c185000c149631844 470 PRINTS PR00149 Fumarate lyase superfamily signature 271 298 3.6E-26 T 14-10-2018 IPR000362 Fumarate lyase family MB46_00500 2302c643dff6c06c185000c149631844 470 PRINTS PR00149 Fumarate lyase superfamily signature 180 198 3.6E-26 T 14-10-2018 IPR000362 Fumarate lyase family MB46_00500 2302c643dff6c06c185000c149631844 470 PRINTS PR00149 Fumarate lyase superfamily signature 135 153 3.6E-26 T 14-10-2018 IPR000362 Fumarate lyase family MB46_00500 2302c643dff6c06c185000c149631844 470 PRINTS PR00149 Fumarate lyase superfamily signature 317 333 3.6E-26 T 14-10-2018 IPR000362 Fumarate lyase family MB46_00500 2302c643dff6c06c185000c149631844 470 Gene3D G3DSA:1.20.200.10 140 407 1.8E-101 T 14-10-2018 MB46_00500 2302c643dff6c06c185000c149631844 470 SUPERFAMILY SSF48557 3 454 3.39E-131 T 14-10-2018 IPR008948 L-Aspartase-like GO:0003824 MB46_00500 2302c643dff6c06c185000c149631844 470 Pfam PF00206 Lyase 11 342 1.4E-89 T 14-10-2018 IPR022761 Fumarate lyase, N-terminal MB46_00500 2302c643dff6c06c185000c149631844 470 Gene3D G3DSA:1.10.40.30 408 455 8.5E-12 T 14-10-2018 MB46_00500 2302c643dff6c06c185000c149631844 470 Gene3D G3DSA:1.10.275.10 1 139 9.5E-55 T 14-10-2018 IPR024083 Fumarase/histidase, N-terminal MB46_00500 2302c643dff6c06c185000c149631844 470 ProSitePatterns PS00163 Fumarate lyases signature. 317 326 - T 14-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 MB46_00500 2302c643dff6c06c185000c149631844 470 Pfam PF10415 Fumarase C C-terminus 408 451 5.4E-11 T 14-10-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 MB46_04815 806a6d113b2c9e02222e6e2fd009ad09 107 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 74 5.2E-15 T 14-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain MB46_04815 806a6d113b2c9e02222e6e2fd009ad09 107 SUPERFAMILY SSF54909 1 93 4.22E-24 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel MB46_04815 806a6d113b2c9e02222e6e2fd009ad09 107 Gene3D G3DSA:3.30.70.100 1 94 5.1E-20 T 14-10-2018 MB46_06070 ef9cc7fa38bfb1e7a366bc2e5f73ac74 352 SUPERFAMILY SSF81345 22 347 1.96E-71 T 14-10-2018 IPR037294 ABC transporter, BtuC-like MB46_06070 ef9cc7fa38bfb1e7a366bc2e5f73ac74 352 Gene3D G3DSA:1.10.3470.10 26 351 2.2E-87 T 14-10-2018 IPR037294 ABC transporter, BtuC-like MB46_06070 ef9cc7fa38bfb1e7a366bc2e5f73ac74 352 Pfam PF01032 FecCD transport family 42 347 3.6E-82 T 14-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 MB46_13735 96e28954797f00e75bce083a136fa75b 149 Gene3D G3DSA:3.10.129.10 2 149 1.5E-37 T 14-10-2018 MB46_13735 96e28954797f00e75bce083a136fa75b 149 Hamap MF_00799 UPF0336 protein . 1 148 29.546 T 14-10-2018 IPR016709 Uncharacterised protein family UPF0336 MB46_13735 96e28954797f00e75bce083a136fa75b 149 PIRSF PIRSF018072 1 149 3.1E-54 T 14-10-2018 IPR016709 Uncharacterised protein family UPF0336 MB46_13735 96e28954797f00e75bce083a136fa75b 149 Pfam PF13452 N-terminal half of MaoC dehydratase 16 137 6.4E-29 T 14-10-2018 IPR039569 N-terminal of MaoC-like dehydratase Reactome: R-HSA-193368|Reactome: R-HSA-2046106|Reactome: R-HSA-389887|Reactome: R-HSA-390247|Reactome: R-HSA-9033241|Reactome: R-HSA-9033500 MB46_13735 96e28954797f00e75bce083a136fa75b 149 SUPERFAMILY SSF54637 9 148 1.12E-35 T 14-10-2018 IPR029069 HotDog domain superfamily MB46_14960 9d215c2f6a468ff3e91dfb0b813ccacc 210 Gene3D G3DSA:3.40.50.300 1 153 6.7E-22 T 14-10-2018 MB46_14960 9d215c2f6a468ff3e91dfb0b813ccacc 210 PIRSF PIRSF035805 1 206 6.6E-45 T 14-10-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 MB46_14960 9d215c2f6a468ff3e91dfb0b813ccacc 210 SUPERFAMILY SSF52540 2 153 2.78E-30 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_14960 9d215c2f6a468ff3e91dfb0b813ccacc 210 Pfam PF00265 Thymidine kinase 3 198 1.0E-32 T 14-10-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 MB46_14960 9d215c2f6a468ff3e91dfb0b813ccacc 210 SUPERFAMILY SSF57716 154 205 8.08E-10 T 14-10-2018 MB46_04740 e4e3f17f35fadf816e3811fdc0febb44 342 Pfam PF00355 Rieske [2Fe-2S] domain 260 315 2.2E-11 T 14-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MB46_04740 e4e3f17f35fadf816e3811fdc0febb44 342 Gene3D G3DSA:2.102.10.10 186 339 3.1E-42 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 MB46_04740 e4e3f17f35fadf816e3811fdc0febb44 342 SUPERFAMILY SSF50022 162 341 8.67E-32 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 MB46_15520 21e4ab7b61b71a35be996bcf2f56fee2 338 Pfam PF09992 Phosphodiester glycosidase 156 336 2.1E-37 T 14-10-2018 IPR018711 Phosphodiester glycosidase MB46_10795 fce881137794430a0668c5f3b60c04e0 402 Pfam PF01594 AI-2E family transporter 78 391 5.7E-59 T 14-10-2018 IPR002549 Transmembrane protein TqsA-like MB46_13645 1bb3880d404fcc216b364174acb91b84 323 Hamap MF_01698 Mycothiol acetyltransferase [mshD]. 12 320 34.058 T 14-10-2018 IPR017813 Mycothiol acetyltransferase GO:0016747 MB46_13645 1bb3880d404fcc216b364174acb91b84 323 Pfam PF00583 Acetyltransferase (GNAT) family 70 143 7.8E-5 T 14-10-2018 IPR000182 GNAT domain MB46_13645 1bb3880d404fcc216b364174acb91b84 323 Pfam PF00583 Acetyltransferase (GNAT) family 213 309 1.1E-14 T 14-10-2018 IPR000182 GNAT domain MB46_13645 1bb3880d404fcc216b364174acb91b84 323 PIRSF PIRSF021524 6 323 1.4E-114 T 14-10-2018 IPR017813 Mycothiol acetyltransferase GO:0016747 MB46_13645 1bb3880d404fcc216b364174acb91b84 323 SUPERFAMILY SSF55729 92 317 1.06E-39 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase MB46_13645 1bb3880d404fcc216b364174acb91b84 323 Gene3D G3DSA:3.40.630.30 16 321 2.3E-84 T 14-10-2018 MB46_13645 1bb3880d404fcc216b364174acb91b84 323 TIGRFAM TIGR03448 mycothiol_MshD: mycothiol synthase 21 318 6.1E-100 T 14-10-2018 IPR017813 Mycothiol acetyltransferase GO:0016747 MB46_06735 6a2ca85dd282235eff1d31e0a1bc2fdc 160 Gene3D G3DSA:2.30.110.10 8 145 3.6E-38 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 MB46_06735 6a2ca85dd282235eff1d31e0a1bc2fdc 160 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 19 137 1.7E-25 T 14-10-2018 IPR024747 Pyridoxamine 5'-phosphate oxidase-related MB46_06735 6a2ca85dd282235eff1d31e0a1bc2fdc 160 SUPERFAMILY SSF50475 13 139 5.79E-28 T 14-10-2018 MB46_15665 ce0fba1c83d7a8d421355ce52885d64d 228 Pfam PF00072 Response regulator receiver domain 19 131 2.9E-27 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MB46_15665 ce0fba1c83d7a8d421355ce52885d64d 228 SMART SM00421 164 221 4.3E-20 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_15665 ce0fba1c83d7a8d421355ce52885d64d 228 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 197 209 4.0E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_15665 ce0fba1c83d7a8d421355ce52885d64d 228 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 197 4.0E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_15665 ce0fba1c83d7a8d421355ce52885d64d 228 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 181 4.0E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_15665 ce0fba1c83d7a8d421355ce52885d64d 228 SMART SM00448 17 130 2.1E-26 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MB46_15665 ce0fba1c83d7a8d421355ce52885d64d 228 SUPERFAMILY SSF52172 16 146 7.26E-32 T 14-10-2018 IPR011006 CheY-like superfamily MB46_15665 ce0fba1c83d7a8d421355ce52885d64d 228 Pfam PF00196 Bacterial regulatory proteins, luxR family 167 220 9.9E-17 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_15665 ce0fba1c83d7a8d421355ce52885d64d 228 SUPERFAMILY SSF46894 157 227 3.33E-20 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MB46_15665 ce0fba1c83d7a8d421355ce52885d64d 228 Gene3D G3DSA:3.40.50.12740 17 227 1.0E-63 T 14-10-2018 MB46_15665 ce0fba1c83d7a8d421355ce52885d64d 228 ProSitePatterns PS00622 LuxR-type HTH domain signature. 181 208 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_12425 df9d59a56b7b54f92824260711b626e8 232 SUPERFAMILY SSF102405 16 217 8.55E-62 T 14-10-2018 MB46_12425 df9d59a56b7b54f92824260711b626e8 232 Gene3D G3DSA:3.40.50.450 23 221 6.5E-66 T 14-10-2018 MB46_12425 df9d59a56b7b54f92824260711b626e8 232 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 46 218 9.1E-41 T 14-10-2018 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG MB46_12425 df9d59a56b7b54f92824260711b626e8 232 Pfam PF03641 Possible lysine decarboxylase 88 216 8.0E-33 T 14-10-2018 IPR031100 LOG family MB46_12810 c8930588474e51933a216b121e7d236d 373 Pfam PF07690 Major Facilitator Superfamily 2 330 6.1E-38 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MB46_12810 c8930588474e51933a216b121e7d236d 373 SUPERFAMILY SSF103473 2 366 4.45E-44 T 14-10-2018 IPR036259 MFS transporter superfamily MB46_12810 c8930588474e51933a216b121e7d236d 373 Gene3D G3DSA:1.20.1250.20 1 368 2.6E-42 T 14-10-2018 MB46_03225 cb942c1d6244c584123adbb08fd66cd3 350 SUPERFAMILY SSF50974 64 340 5.23E-27 T 14-10-2018 IPR011045 Nitrous oxide reductase, N-terminal Reactome: R-HSA-114608 MB46_03225 cb942c1d6244c584123adbb08fd66cd3 350 Pfam PF10282 Lactonase, 7-bladed beta-propeller 7 348 1.2E-53 T 14-10-2018 IPR019405 Lactonase, 7-bladed beta propeller MB46_03225 cb942c1d6244c584123adbb08fd66cd3 350 Gene3D G3DSA:2.130.10.10 5 350 4.5E-68 T 14-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 MB46_03930 15dfd45195aac6a333a637a06ed260a1 310 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 10 302 27.029 T 14-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 MB46_03930 15dfd45195aac6a333a637a06ed260a1 310 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 10 289 2.2E-81 T 14-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 MB46_03930 15dfd45195aac6a333a637a06ed260a1 310 Pfam PF01715 IPP transferase 43 283 1.1E-73 T 14-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 MB46_03930 15dfd45195aac6a333a637a06ed260a1 310 SUPERFAMILY SSF52540 11 154 1.87E-18 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_03930 15dfd45195aac6a333a637a06ed260a1 310 Gene3D G3DSA:3.40.50.300 14 286 1.9E-89 T 14-10-2018 MB46_03930 15dfd45195aac6a333a637a06ed260a1 310 Gene3D G3DSA:1.10.20.140 117 185 1.9E-89 T 14-10-2018 MB46_11015 d70e16c5571b1842bbdf18a16eb9fff7 341 SUPERFAMILY SSF55486 154 316 6.85E-11 T 14-10-2018 MB46_11015 d70e16c5571b1842bbdf18a16eb9fff7 341 Gene3D G3DSA:3.40.390.10 158 335 2.4E-8 T 14-10-2018 IPR024079 Metallopeptidase, catalytic domain superfamily GO:0008237 MB46_11015 d70e16c5571b1842bbdf18a16eb9fff7 341 Pfam PF00413 Matrixin 289 330 7.6E-6 T 14-10-2018 IPR001818 Peptidase M10, metallopeptidase GO:0004222|GO:0006508|GO:0008270|GO:0031012 MB46_12710 9a730dd7f60ce4ba066ff72389d6f2e9 343 Pfam PF03060 Nitronate monooxygenase 3 336 4.8E-65 T 14-10-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 MB46_12710 9a730dd7f60ce4ba066ff72389d6f2e9 343 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 209 229 - T 14-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 MB46_12710 9a730dd7f60ce4ba066ff72389d6f2e9 343 Gene3D G3DSA:3.20.20.70 1 343 1.1E-87 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MB46_12710 9a730dd7f60ce4ba066ff72389d6f2e9 343 SUPERFAMILY SSF51412 4 320 1.98E-43 T 14-10-2018 MB46_18170 1c921ad5add80f70900171f611ab55ee 335 Gene3D G3DSA:3.40.50.1100 66 164 4.7E-109 T 14-10-2018 MB46_18170 1c921ad5add80f70900171f611ab55ee 335 SUPERFAMILY SSF53686 5 333 2.19E-92 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme MB46_18170 1c921ad5add80f70900171f611ab55ee 335 Gene3D G3DSA:3.40.50.1100 8 327 4.7E-109 T 14-10-2018 MB46_18170 1c921ad5add80f70900171f611ab55ee 335 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 13 320 7.8E-42 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme MB46_18170 1c921ad5add80f70900171f611ab55ee 335 PIRSF PIRSF006278 1 335 2.3E-115 T 14-10-2018 IPR027278 1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase MB46_18170 1c921ad5add80f70900171f611ab55ee 335 TIGRFAM TIGR01274 ACC_deam: 1-aminocyclopropane-1-carboxylate deaminase 3 335 6.5E-168 T 14-10-2018 IPR005965 1-aminocyclopropane-1-carboxylate deaminase GO:0008660|GO:0009310|GO:0030170 KEGG: 00270+3.5.99.7 MB46_02270 89dc4c81c246c8d8ced7c8214d8e7e02 135 Pfam PF12005 Protein of unknown function (DUF3499) 5 131 3.4E-45 T 14-10-2018 IPR021888 Protein of unknown function DUF3499 MB46_13925 badd6770ab10df526cc203f9401dadf1 316 Gene3D G3DSA:3.40.190.290 92 307 5.4E-31 T 14-10-2018 MB46_13925 badd6770ab10df526cc203f9401dadf1 316 Pfam PF03466 LysR substrate binding domain 90 299 1.4E-30 T 14-10-2018 IPR005119 LysR, substrate-binding MB46_13925 badd6770ab10df526cc203f9401dadf1 316 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 1.6E-11 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MB46_13925 badd6770ab10df526cc203f9401dadf1 316 Gene3D G3DSA:1.10.10.10 1 91 1.2E-15 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_13925 badd6770ab10df526cc203f9401dadf1 316 SUPERFAMILY SSF46785 2 111 1.06E-14 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_13925 badd6770ab10df526cc203f9401dadf1 316 SUPERFAMILY SSF53850 90 302 1.46E-25 T 14-10-2018 MB46_03035 bbc049fbc594dc9a187eeee8007597be 98 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 21 91 3.5E-14 T 14-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 MB46_03035 bbc049fbc594dc9a187eeee8007597be 98 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 4 96 5.7E-22 T 14-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 MB46_03035 bbc049fbc594dc9a187eeee8007597be 98 SUPERFAMILY SSF141000 4 94 6.41E-25 T 14-10-2018 IPR036113 Glu-tRNAGln amidotransferase superfamily, subunit C GO:0006450 MB46_03035 bbc049fbc594dc9a187eeee8007597be 98 Gene3D G3DSA:1.10.20.60 2 94 1.2E-20 T 14-10-2018 MB46_03035 bbc049fbc594dc9a187eeee8007597be 98 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 3 96 20.62 T 14-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 MB46_17300 8bbb70a4aeec700d3ce146b0d8381e99 121 Gene3D G3DSA:2.20.25.10 1 43 7.8E-20 T 14-10-2018 MB46_17300 8bbb70a4aeec700d3ce146b0d8381e99 121 TIGRFAM TIGR00686 phnA: putative alkylphosphonate utilization operon protein PhnA 5 120 6.0E-35 T 14-10-2018 IPR004624 PhnA protein MB46_17300 8bbb70a4aeec700d3ce146b0d8381e99 121 SUPERFAMILY SSF57783 4 38 3.23E-13 T 14-10-2018 MB46_17300 8bbb70a4aeec700d3ce146b0d8381e99 121 SUPERFAMILY SSF82057 47 121 2.2E-22 T 14-10-2018 MB46_17300 8bbb70a4aeec700d3ce146b0d8381e99 121 Pfam PF03831 PhnA domain 52 121 1.5E-27 T 14-10-2018 IPR013988 PhnA protein, C-terminal MB46_17300 8bbb70a4aeec700d3ce146b0d8381e99 121 Gene3D G3DSA:2.30.30.40 49 121 2.5E-28 T 14-10-2018 MB46_17300 8bbb70a4aeec700d3ce146b0d8381e99 121 Pfam PF08274 PhnA Zinc-Ribbon 4 33 4.1E-15 T 14-10-2018 IPR013987 PhnA protein, N-terminal MB46_01955 34a45c9242c8f52345d64d065b8c922c 416 Pfam PF02653 Branched-chain amino acid transport system / permease component 119 396 1.2E-42 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 MB46_07910 bae09fc081ca9f867a49604c2cd048e1 256 PIRSF PIRSF010219 44 256 1.0E-69 T 14-10-2018 IPR016566 Uncharacterised conserved protein UCP010219 MB46_07910 bae09fc081ca9f867a49604c2cd048e1 256 Pfam PF11361 Protein of unknown function (DUF3159) 68 249 1.3E-64 T 14-10-2018 IPR016566 Uncharacterised conserved protein UCP010219 MB46_09945 d3aa4ed947c07e48b3f60310cd81fba3 238 Gene3D G3DSA:1.10.10.10 6 74 2.4E-14 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_09945 d3aa4ed947c07e48b3f60310cd81fba3 238 Pfam PF09339 IclR helix-turn-helix domain 10 57 3.6E-12 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 MB46_09945 d3aa4ed947c07e48b3f60310cd81fba3 238 SUPERFAMILY SSF55781 62 234 7.19E-34 T 14-10-2018 MB46_09945 d3aa4ed947c07e48b3f60310cd81fba3 238 Gene3D G3DSA:3.30.450.40 75 229 3.8E-34 T 14-10-2018 IPR029016 GAF-like domain superfamily MB46_09945 d3aa4ed947c07e48b3f60310cd81fba3 238 Pfam PF01614 Bacterial transcriptional regulator 125 230 7.3E-16 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal MB46_09945 d3aa4ed947c07e48b3f60310cd81fba3 238 SMART SM00346 7 93 8.1E-19 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 MB46_09945 d3aa4ed947c07e48b3f60310cd81fba3 238 SUPERFAMILY SSF46785 7 75 1.15E-11 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_17800 91a8250824f8e05ef7417ffa8fdb16ad 545 SUPERFAMILY SSF52540 5 247 2.19E-37 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_17800 91a8250824f8e05ef7417ffa8fdb16ad 545 Pfam PF00005 ABC transporter 21 187 1.0E-21 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_17800 91a8250824f8e05ef7417ffa8fdb16ad 545 SMART SM00382 374 541 4.1E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_17800 91a8250824f8e05ef7417ffa8fdb16ad 545 SMART SM00382 29 232 3.4E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_17800 91a8250824f8e05ef7417ffa8fdb16ad 545 Gene3D G3DSA:3.40.50.300 341 544 2.4E-40 T 14-10-2018 MB46_17800 91a8250824f8e05ef7417ffa8fdb16ad 545 Gene3D G3DSA:3.40.50.300 11 323 1.8E-50 T 14-10-2018 MB46_17800 91a8250824f8e05ef7417ffa8fdb16ad 545 SUPERFAMILY SSF52540 347 543 7.96E-38 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_17800 91a8250824f8e05ef7417ffa8fdb16ad 545 Pfam PF00005 ABC transporter 367 495 3.1E-20 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_19530 0f46f0b53eda00504c68576d60c656fb 108 Gene3D G3DSA:1.10.10.10 24 106 6.2E-10 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_19530 0f46f0b53eda00504c68576d60c656fb 108 SUPERFAMILY SSF46785 27 96 9.4E-11 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_19530 0f46f0b53eda00504c68576d60c656fb 108 Pfam PF12840 Helix-turn-helix domain 26 73 4.0E-7 T 14-10-2018 MB46_01135 9d0ff514ec63cb37115621c79e77caec 124 SUPERFAMILY SSF54593 5 123 6.31E-20 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MB46_01135 9d0ff514ec63cb37115621c79e77caec 124 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 118 2.2E-4 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MB46_01135 9d0ff514ec63cb37115621c79e77caec 124 Gene3D G3DSA:3.10.180.10 3 122 2.4E-21 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MB46_14565 f0cd16dc8a9d88205125940f3023f75a 231 SUPERFAMILY SSF52799 10 160 4.1E-27 T 14-10-2018 IPR029021 Protein-tyrosine phosphatase-like MB46_14565 f0cd16dc8a9d88205125940f3023f75a 231 Pfam PF13350 Tyrosine phosphatase family 18 207 2.1E-26 T 14-10-2018 IPR026893 Tyrosine/serine-protein phosphatase IphP-type MB46_14565 f0cd16dc8a9d88205125940f3023f75a 231 ProSitePatterns PS00383 Tyrosine specific protein phosphatases active site. 130 140 - T 14-10-2018 IPR016130 Protein-tyrosine phosphatase, active site GO:0004725|GO:0016311 MB46_14565 f0cd16dc8a9d88205125940f3023f75a 231 Gene3D G3DSA:3.90.190.10 9 230 3.6E-30 T 14-10-2018 IPR029021 Protein-tyrosine phosphatase-like MB46_10820 ec4e98dd3dc81fb49c0d99e67110b650 825 Pfam PF09924 Uncharacterised conserved protein (DUF2156) 498 791 1.5E-93 T 14-10-2018 IPR024320 Phosphatidylglycerol lysyltransferase, C-terminal MB46_10820 ec4e98dd3dc81fb49c0d99e67110b650 825 SUPERFAMILY SSF144091 20 209 1.57E-5 T 14-10-2018 MB46_18855 5239b40f8130c95abb98ebf216d86868 104 Gene3D G3DSA:3.30.70.100 1 95 2.5E-19 T 14-10-2018 MB46_18855 5239b40f8130c95abb98ebf216d86868 104 SUPERFAMILY SSF54909 3 103 1.02E-23 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel MB46_18855 5239b40f8130c95abb98ebf216d86868 104 Pfam PF05336 L-rhamnose mutarotase 4 101 6.7E-20 T 14-10-2018 IPR008000 Rhamnose/fucose mutarotase GO:0005737|GO:0016857 MB46_13890 df29345f926c9ff385b72f7b12068add 147 SUPERFAMILY SSF55961 1 143 2.93E-12 T 14-10-2018 MB46_13890 df29345f926c9ff385b72f7b12068add 147 Gene3D G3DSA:3.30.530.20 1 145 2.2E-10 T 14-10-2018 IPR023393 START-like domain superfamily MB46_07690 d8c49dc8c3af268bd00e65c76680ac2b 224 SUPERFAMILY SSF142695 14 185 1.09E-51 T 14-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 MB46_07690 d8c49dc8c3af268bd00e65c76680ac2b 224 Pfam PF00925 GTP cyclohydrolase II 14 183 2.1E-58 T 14-10-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 MB46_07690 d8c49dc8c3af268bd00e65c76680ac2b 224 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 6 209 36.433 T 14-10-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 MB46_07690 d8c49dc8c3af268bd00e65c76680ac2b 224 Gene3D G3DSA:3.40.50.10990 11 186 1.4E-62 T 14-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 MB46_08860 3ebc0d09be351db3836d051cc5971fcc 309 SMART SM00327 40 223 2.3E-4 T 14-10-2018 IPR002035 von Willebrand factor, type A MB46_08860 3ebc0d09be351db3836d051cc5971fcc 309 Gene3D G3DSA:3.40.50.410 34 254 1.7E-26 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily MB46_08860 3ebc0d09be351db3836d051cc5971fcc 309 Pfam PF13519 von Willebrand factor type A domain 44 158 2.6E-9 T 14-10-2018 IPR002035 von Willebrand factor, type A MB46_08860 3ebc0d09be351db3836d051cc5971fcc 309 SUPERFAMILY SSF53300 40 228 1.15E-12 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily MB46_18565 03b2d4a281facf831f2c26ecc5b55d4f 660 SUPERFAMILY SSF52540 297 470 7.05E-7 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_05390 2f915cbe0302112b489dde9ace511770 365 Pfam PF08704 tRNA methyltransferase complex GCD14 subunit 101 266 2.8E-19 T 14-10-2018 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 MetaCyc: PWY-6829 MB46_05390 2f915cbe0302112b489dde9ace511770 365 Gene3D G3DSA:3.40.50.150 96 295 2.1E-53 T 14-10-2018 MB46_05390 2f915cbe0302112b489dde9ace511770 365 Pfam PF14801 tRNA methyltransferase complex GCD14 subunit N-term 31 81 3.0E-25 T 14-10-2018 MB46_05390 2f915cbe0302112b489dde9ace511770 365 SUPERFAMILY SSF53335 33 290 4.13E-63 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MB46_05390 2f915cbe0302112b489dde9ace511770 365 Gene3D G3DSA:3.10.330.20 28 94 5.6E-22 T 14-10-2018 MB46_10370 96fff54d0b438f8b6ca994c83438ee48 404 Pfam PF05065 Phage capsid family 124 394 2.0E-59 T 14-10-2018 IPR024455 Phage capsid MB46_10370 96fff54d0b438f8b6ca994c83438ee48 404 TIGRFAM TIGR01554 major_cap_HK97: phage major capsid protein, HK97 family 10 399 1.2E-82 T 14-10-2018 IPR024455 Phage capsid MB46_10370 96fff54d0b438f8b6ca994c83438ee48 404 Gene3D G3DSA:3.30.2320.10 253 352 3.1E-20 T 14-10-2018 MB46_10370 96fff54d0b438f8b6ca994c83438ee48 404 Gene3D G3DSA:3.30.2400.10 167 384 3.1E-20 T 14-10-2018 MB46_10370 96fff54d0b438f8b6ca994c83438ee48 404 SUPERFAMILY SSF56563 116 397 1.7E-58 T 14-10-2018 MB46_05975 079b8cdafbecf84a2215ce81985b3f47 371 SUPERFAMILY SSF54373 214 318 6.28E-13 T 14-10-2018 MB46_05975 079b8cdafbecf84a2215ce81985b3f47 371 Gene3D G3DSA:3.30.9.10 88 319 1.3E-96 T 14-10-2018 MB46_05975 079b8cdafbecf84a2215ce81985b3f47 371 SUPERFAMILY SSF51905 5 364 1.55E-33 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_05975 079b8cdafbecf84a2215ce81985b3f47 371 Gene3D G3DSA:3.50.50.60 6 356 1.3E-96 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_05975 079b8cdafbecf84a2215ce81985b3f47 371 Pfam PF01266 FAD dependent oxidoreductase 6 354 3.0E-47 T 14-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 MB46_14830 fa01cee127588c898c9daf60b85f2c55 263 Gene3D G3DSA:3.20.20.150 1 259 2.3E-57 T 14-10-2018 MB46_14830 fa01cee127588c898c9daf60b85f2c55 263 SUPERFAMILY SSF51658 1 249 8.84E-52 T 14-10-2018 IPR036237 Xylose isomerase-like superfamily MB46_14830 fa01cee127588c898c9daf60b85f2c55 263 Pfam PF01261 Xylose isomerase-like TIM barrel 21 221 6.1E-25 T 14-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain MB46_14830 fa01cee127588c898c9daf60b85f2c55 263 PIRSF PIRSF006241 1 260 7.3E-62 T 14-10-2018 IPR026040 Hydroxypyruvate isomerase-like MB46_10585 24a1aa9e126178515be419b3add20a27 393 Gene3D G3DSA:3.40.640.10 13 266 2.6E-126 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MB46_10585 24a1aa9e126178515be419b3add20a27 393 Gene3D G3DSA:3.90.1150.10 3 373 2.6E-126 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MB46_10585 24a1aa9e126178515be419b3add20a27 393 Pfam PF00266 Aminotransferase class-V 2 372 1.1E-63 T 14-10-2018 IPR000192 Aminotransferase class V domain MB46_10585 24a1aa9e126178515be419b3add20a27 393 SUPERFAMILY SSF53383 1 384 2.04E-89 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MB46_10585 24a1aa9e126178515be419b3add20a27 393 PIRSF PIRSF005572 1 389 7.0E-112 T 14-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 MB46_10585 24a1aa9e126178515be419b3add20a27 393 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 203 222 - T 14-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site MB46_01790 71998c0e45177c0f2c3e06b6443b4d9e 525 Gene3D G3DSA:1.20.1740.10 55 506 6.7E-116 T 14-10-2018 MB46_01790 71998c0e45177c0f2c3e06b6443b4d9e 525 Pfam PF13520 Amino acid permease 59 463 4.6E-59 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 MB46_01790 71998c0e45177c0f2c3e06b6443b4d9e 525 PIRSF PIRSF006060 38 503 3.9E-92 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 MB46_06725 6c6a0fe80851cee80aac3c0120a8e223 230 Gene3D G3DSA:3.40.50.12740 17 222 1.0E-56 T 14-10-2018 MB46_06725 6c6a0fe80851cee80aac3c0120a8e223 230 ProSitePatterns PS00622 LuxR-type HTH domain signature. 178 205 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_06725 6c6a0fe80851cee80aac3c0120a8e223 230 SMART SM00421 161 218 6.3E-20 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_06725 6c6a0fe80851cee80aac3c0120a8e223 230 SUPERFAMILY SSF52172 16 188 2.28E-27 T 14-10-2018 IPR011006 CheY-like superfamily MB46_06725 6c6a0fe80851cee80aac3c0120a8e223 230 SMART SM00448 17 129 1.2E-25 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MB46_06725 6c6a0fe80851cee80aac3c0120a8e223 230 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 178 4.8E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_06725 6c6a0fe80851cee80aac3c0120a8e223 230 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 178 194 4.8E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_06725 6c6a0fe80851cee80aac3c0120a8e223 230 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 194 206 4.8E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_06725 6c6a0fe80851cee80aac3c0120a8e223 230 Pfam PF00196 Bacterial regulatory proteins, luxR family 163 217 1.8E-14 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_06725 6c6a0fe80851cee80aac3c0120a8e223 230 Pfam PF00072 Response regulator receiver domain 19 129 1.5E-23 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MB46_08650 7b227e91d8874963a1f38664bbcb1135 335 Pfam PF02355 Protein export membrane protein 112 307 7.6E-46 T 14-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial MB46_08650 7b227e91d8874963a1f38664bbcb1135 335 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 47 298 3.3E-52 T 14-10-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 MB46_08650 7b227e91d8874963a1f38664bbcb1135 335 Gene3D G3DSA:1.20.1640.10 128 321 1.3E-9 T 14-10-2018 MB46_08650 7b227e91d8874963a1f38664bbcb1135 335 Pfam PF07549 SecD/SecF GG Motif 47 62 4.7E-5 T 14-10-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site MB46_08650 7b227e91d8874963a1f38664bbcb1135 335 PRINTS PR01755 Bacterial translocase SecF protein signature 206 224 1.4E-17 T 14-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial MB46_08650 7b227e91d8874963a1f38664bbcb1135 335 PRINTS PR01755 Bacterial translocase SecF protein signature 241 256 1.4E-17 T 14-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial MB46_08650 7b227e91d8874963a1f38664bbcb1135 335 PRINTS PR01755 Bacterial translocase SecF protein signature 46 61 1.4E-17 T 14-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial MB46_08650 7b227e91d8874963a1f38664bbcb1135 335 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 18 309 23.193 T 14-10-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 MB46_08650 7b227e91d8874963a1f38664bbcb1135 335 SUPERFAMILY SSF82866 95 309 1.83E-32 T 14-10-2018 MB46_13935 3651498920ab5519b51426e060778031 273 SUPERFAMILY SSF161098 75 258 2.62E-29 T 14-10-2018 IPR035906 MetI-like superfamily MB46_13935 3651498920ab5519b51426e060778031 273 Gene3D G3DSA:1.10.3720.10 75 264 1.5E-20 T 14-10-2018 IPR035906 MetI-like superfamily MB46_13935 3651498920ab5519b51426e060778031 273 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 99 265 4.0E-21 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_16315 e00c45a59c84c495d4fd52b87acbe03b 148 Pfam PF08818 Domain of unknown function (DU1801) 27 129 2.8E-10 T 14-10-2018 IPR014922 Domain of unknown function DUF1801 MB46_16195 b02be03d056c9c47e65dd1fae79f93ca 265 Pfam PF04203 Sortase family 110 239 5.3E-24 T 14-10-2018 IPR005754 Sortase family MB46_16195 b02be03d056c9c47e65dd1fae79f93ca 265 Gene3D G3DSA:2.40.260.10 53 257 1.5E-42 T 14-10-2018 IPR023365 Sortase domain superfamily MB46_16195 b02be03d056c9c47e65dd1fae79f93ca 265 SUPERFAMILY SSF63817 99 244 5.36E-24 T 14-10-2018 IPR023365 Sortase domain superfamily MB46_10070 ea0bd6e574c69b270ad284389571b453 102 TIGRFAM TIGR03462 CarR_dom_SF: lycopene cyclase domain 8 93 1.1E-14 T 14-10-2018 IPR017825 Lycopene cyclase domain GO:0016872 KEGG: 00906+2.5.1.32+5.5.1.19|MetaCyc: PWY-5943|MetaCyc: PWY-5947|MetaCyc: PWY-6279|MetaCyc: PWY-7591|MetaCyc: PWY-7938|MetaCyc: PWY-7939|MetaCyc: PWY-7947 MB46_02695 5a5a16661d864aa7b200291f10205ec0 166 Pfam PF10698 Protein of unknown function (DUF2505) 6 162 3.5E-33 T 14-10-2018 IPR019639 Protein of unknown function DUF2505 MB46_13185 889129b4f35d746dd3d2164603817f5a 427 SUPERFAMILY SSF53850 24 405 8.89E-60 T 14-10-2018 MB46_13185 889129b4f35d746dd3d2164603817f5a 427 Gene3D G3DSA:3.40.190.10 48 364 9.3E-89 T 14-10-2018 MB46_13185 889129b4f35d746dd3d2164603817f5a 427 Gene3D G3DSA:3.40.190.10 148 382 9.3E-89 T 14-10-2018 MB46_13185 889129b4f35d746dd3d2164603817f5a 427 Pfam PF13416 Bacterial extracellular solute-binding protein 51 360 2.7E-33 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein MB46_13185 889129b4f35d746dd3d2164603817f5a 427 ProSitePatterns PS01037 Bacterial extracellular solute-binding proteins, family 1 signature. 142 159 - T 14-10-2018 IPR006061 Solute-binding family 1, conserved site GO:0055085 MB46_11485 ea45bc0b1d279ca451d5d384e921b697 119 Pfam PF10066 Uncharacterized conserved protein (DUF2304) 5 109 3.1E-20 T 14-10-2018 IPR019277 Protein of unknown function DUF2304 MB46_07930 4642cfc89ade2dbcb0e1e1d630684ed2 165 Pfam PF11292 Protein of unknown function (DUF3093) 17 154 3.5E-44 T 14-10-2018 IPR021443 Protein of unknown function DUF3093 MB46_00615 2624d90304c99c61157663f0fc5384fe 303 SUPERFAMILY SSF53807 25 302 2.89E-70 T 14-10-2018 MB46_00615 2624d90304c99c61157663f0fc5384fe 303 Gene3D G3DSA:3.40.50.1980 179 302 1.0E-35 T 14-10-2018 MB46_00615 2624d90304c99c61157663f0fc5384fe 303 PRINTS PR00690 Adhesin family signature 185 206 4.0E-23 T 14-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 MB46_00615 2624d90304c99c61157663f0fc5384fe 303 PRINTS PR00690 Adhesin family signature 59 72 4.0E-23 T 14-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 MB46_00615 2624d90304c99c61157663f0fc5384fe 303 PRINTS PR00690 Adhesin family signature 267 286 4.0E-23 T 14-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 MB46_00615 2624d90304c99c61157663f0fc5384fe 303 PRINTS PR00690 Adhesin family signature 72 89 4.0E-23 T 14-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 MB46_00615 2624d90304c99c61157663f0fc5384fe 303 PRINTS PR00690 Adhesin family signature 28 46 4.0E-23 T 14-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 MB46_00615 2624d90304c99c61157663f0fc5384fe 303 PRINTS PR00690 Adhesin family signature 240 258 4.0E-23 T 14-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 MB46_00615 2624d90304c99c61157663f0fc5384fe 303 Pfam PF01297 Zinc-uptake complex component A periplasmic 31 299 2.8E-68 T 14-10-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 MB46_00615 2624d90304c99c61157663f0fc5384fe 303 Gene3D G3DSA:3.40.50.1980 30 178 9.0E-35 T 14-10-2018 MB46_00615 2624d90304c99c61157663f0fc5384fe 303 PRINTS PR00691 Adhesin B signature 72 91 1.3E-19 T 14-10-2018 IPR006129 Adhesin B GO:0007155 MB46_00615 2624d90304c99c61157663f0fc5384fe 303 PRINTS PR00691 Adhesin B signature 236 253 1.3E-19 T 14-10-2018 IPR006129 Adhesin B GO:0007155 MB46_00615 2624d90304c99c61157663f0fc5384fe 303 PRINTS PR00691 Adhesin B signature 280 298 1.3E-19 T 14-10-2018 IPR006129 Adhesin B GO:0007155 MB46_00615 2624d90304c99c61157663f0fc5384fe 303 PRINTS PR00691 Adhesin B signature 28 49 1.3E-19 T 14-10-2018 IPR006129 Adhesin B GO:0007155 MB46_00615 2624d90304c99c61157663f0fc5384fe 303 PRINTS PR00691 Adhesin B signature 185 202 1.3E-19 T 14-10-2018 IPR006129 Adhesin B GO:0007155 MB46_00615 2624d90304c99c61157663f0fc5384fe 303 PRINTS PR00691 Adhesin B signature 53 71 1.3E-19 T 14-10-2018 IPR006129 Adhesin B GO:0007155 MB46_03360 f21b8ae2649bd3c08f7fee89d19e1eef 279 Pfam PF07332 Putative Actinobacterial Holin-X, holin superfamily III 27 140 5.2E-20 T 14-10-2018 IPR009937 Putative Actinobacterial Holin-X, holin superfamily III MB46_01560 d5fb2dabb7d23236a0185626fb9e46aa 297 Pfam PF12146 Serine aminopeptidase, S33 37 257 2.1E-14 T 14-10-2018 IPR022742 Serine aminopeptidase, S33 MB46_01560 d5fb2dabb7d23236a0185626fb9e46aa 297 SUPERFAMILY SSF53474 12 293 1.22E-31 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_01560 d5fb2dabb7d23236a0185626fb9e46aa 297 Gene3D G3DSA:3.40.50.1820 2 295 3.7E-27 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_01560 d5fb2dabb7d23236a0185626fb9e46aa 297 PIRSF PIRSF037442 4 297 1.6E-78 T 14-10-2018 IPR017208 Uncharacterised conserved protein UCP037442, alpha/beta hydrolase, RSp0795 MB46_03080 da3bc75e7270d13e7fa133b77cb02a97 332 SUPERFAMILY SSF53822 76 328 1.12E-32 T 14-10-2018 IPR028082 Periplasmic binding protein-like I MB46_03080 da3bc75e7270d13e7fa133b77cb02a97 332 Gene3D G3DSA:3.40.50.2300 63 160 1.1E-33 T 14-10-2018 MB46_03080 da3bc75e7270d13e7fa133b77cb02a97 332 Gene3D G3DSA:3.40.50.2300 161 289 1.1E-33 T 14-10-2018 MB46_03080 da3bc75e7270d13e7fa133b77cb02a97 332 Gene3D G3DSA:1.10.260.40 2 62 4.2E-19 T 14-10-2018 MB46_03080 da3bc75e7270d13e7fa133b77cb02a97 332 SUPERFAMILY SSF47413 3 67 4.03E-14 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MB46_03080 da3bc75e7270d13e7fa133b77cb02a97 332 Pfam PF00356 Bacterial regulatory proteins, lacI family 5 55 1.6E-14 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MB46_03080 da3bc75e7270d13e7fa133b77cb02a97 332 SMART SM00354 3 78 3.1E-17 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MB46_03080 da3bc75e7270d13e7fa133b77cb02a97 332 Pfam PF13377 Periplasmic binding protein-like domain 176 327 3.9E-20 T 14-10-2018 MB46_19700 d71767b68c00e8a203a10a0ba1529142 168 Gene3D G3DSA:3.40.630.30 1 168 2.5E-39 T 14-10-2018 MB46_19700 d71767b68c00e8a203a10a0ba1529142 168 SUPERFAMILY SSF55729 2 164 9.55E-38 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase MB46_19700 d71767b68c00e8a203a10a0ba1529142 168 Pfam PF13302 Acetyltransferase (GNAT) domain 2 141 1.1E-16 T 14-10-2018 IPR000182 GNAT domain MB46_01065 275abf6d8498891f90ed197a7441255d 283 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 91 104 - T 14-10-2018 IPR020583 Inositol monophosphatase, metal-binding site MB46_01065 275abf6d8498891f90ed197a7441255d 283 Pfam PF00459 Inositol monophosphatase family 15 250 6.7E-35 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MB46_01065 275abf6d8498891f90ed197a7441255d 283 Gene3D G3DSA:3.40.190.80 168 277 5.7E-12 T 14-10-2018 MB46_01065 275abf6d8498891f90ed197a7441255d 283 Gene3D G3DSA:3.30.540.10 6 162 3.6E-29 T 14-10-2018 MB46_01065 275abf6d8498891f90ed197a7441255d 283 SUPERFAMILY SSF56655 13 274 3.66E-48 T 14-10-2018 MB46_01065 275abf6d8498891f90ed197a7441255d 283 PRINTS PR00377 Inositol monophosphatase superfamily signature 229 253 4.3E-24 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MB46_01065 275abf6d8498891f90ed197a7441255d 283 PRINTS PR00377 Inositol monophosphatase superfamily signature 152 175 4.3E-24 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MB46_01065 275abf6d8498891f90ed197a7441255d 283 PRINTS PR00377 Inositol monophosphatase superfamily signature 49 69 4.3E-24 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MB46_01065 275abf6d8498891f90ed197a7441255d 283 PRINTS PR00377 Inositol monophosphatase superfamily signature 91 107 4.3E-24 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MB46_01065 275abf6d8498891f90ed197a7441255d 283 PRINTS PR00377 Inositol monophosphatase superfamily signature 71 87 4.3E-24 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MB46_01065 275abf6d8498891f90ed197a7441255d 283 PRINTS PR00377 Inositol monophosphatase superfamily signature 198 219 4.3E-24 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MB46_00365 f82458260f066db8ee9ebf5fa9391841 608 SUPERFAMILY SSF52540 362 600 1.55E-58 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_00365 f82458260f066db8ee9ebf5fa9391841 608 Pfam PF00005 ABC transporter 383 531 4.4E-20 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_00365 f82458260f066db8ee9ebf5fa9391841 608 SMART SM00382 391 577 1.0E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_00365 f82458260f066db8ee9ebf5fa9391841 608 SUPERFAMILY SSF90123 33 338 1.27E-55 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MB46_00365 f82458260f066db8ee9ebf5fa9391841 608 Pfam PF00664 ABC transporter transmembrane region 45 313 3.4E-31 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 MB46_00365 f82458260f066db8ee9ebf5fa9391841 608 Gene3D G3DSA:1.20.1560.10 15 341 7.1E-54 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MB46_00365 f82458260f066db8ee9ebf5fa9391841 608 Gene3D G3DSA:3.40.50.300 361 606 2.8E-59 T 14-10-2018 MB46_15695 9fb88370eb447d8a39e8c18ef0207a3c 509 PIRSF PIRSF006060 7 496 2.5E-57 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 MB46_15695 9fb88370eb447d8a39e8c18ef0207a3c 509 Gene3D G3DSA:1.20.1740.10 20 459 3.3E-46 T 14-10-2018 MB46_15695 9fb88370eb447d8a39e8c18ef0207a3c 509 Pfam PF13520 Amino acid permease 31 470 9.7E-30 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 MB46_10685 dcb9243a17fb731e6f1a7d6d89cc34bc 135 SUPERFAMILY SSF142906 17 119 2.62E-8 T 14-10-2018 IPR038056 YjbR-like superfamily MB46_10685 dcb9243a17fb731e6f1a7d6d89cc34bc 135 Pfam PF04237 YjbR 22 113 3.2E-13 T 14-10-2018 IPR007351 Uncharacterised protein YjbR MB46_08520 896bcb08b0413d5ea713311348d90426 166 Gene3D G3DSA:1.25.40.10 18 165 1.4E-8 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MB46_08520 896bcb08b0413d5ea713311348d90426 166 SUPERFAMILY SSF48452 47 142 1.26E-6 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MB46_15715 ba47cec676367130f22a802ceb0a2c3e 141 Pfam PF07681 DoxX 9 89 7.6E-5 T 14-10-2018 IPR032808 DoxX family MB46_00285 5ba3cb46b1dfad06655ebbacf90b0d99 311 SUPERFAMILY SSF51569 40 290 2.67E-33 T 14-10-2018 MB46_00285 5ba3cb46b1dfad06655ebbacf90b0d99 311 Gene3D G3DSA:3.20.20.70 12 309 1.1E-80 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MB46_12470 56a3a1b25afa1981e83b7212589462f9 510 Pfam PF00174 Oxidoreductase molybdopterin binding domain 236 388 2.5E-37 T 14-10-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 MB46_12470 56a3a1b25afa1981e83b7212589462f9 510 SUPERFAMILY SSF81296 399 509 5.18E-19 T 14-10-2018 IPR014756 Immunoglobulin E-set MB46_12470 56a3a1b25afa1981e83b7212589462f9 510 Gene3D G3DSA:2.60.40.650 404 510 9.7E-22 T 14-10-2018 MB46_12470 56a3a1b25afa1981e83b7212589462f9 510 SUPERFAMILY SSF56524 214 405 2.62E-54 T 14-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 MB46_12470 56a3a1b25afa1981e83b7212589462f9 510 Gene3D G3DSA:3.90.420.10 182 403 1.3E-48 T 14-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 MB46_15280 5cbc6704435a1ad23d41338180815bdc 534 Gene3D G3DSA:1.20.1250.20 53 484 1.5E-65 T 14-10-2018 MB46_15280 5cbc6704435a1ad23d41338180815bdc 534 Pfam PF00083 Sugar (and other) transporter 59 477 9.5E-38 T 14-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 MB46_15280 5cbc6704435a1ad23d41338180815bdc 534 ProSitePatterns PS00216 Sugar transport proteins signature 1. 345 362 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MB46_15280 5cbc6704435a1ad23d41338180815bdc 534 ProSitePatterns PS00217 Sugar transport proteins signature 2. 164 189 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MB46_15280 5cbc6704435a1ad23d41338180815bdc 534 SUPERFAMILY SSF103473 49 477 7.32E-71 T 14-10-2018 IPR036259 MFS transporter superfamily MB46_14995 41ede177add35cb7acf592cbc69deb6b 311 SUPERFAMILY SSF160964 24 58 3.53E-6 T 14-10-2018 MB46_14995 41ede177add35cb7acf592cbc69deb6b 311 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 104 300 2.3E-17 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_14995 41ede177add35cb7acf592cbc69deb6b 311 Gene3D G3DSA:1.10.3720.10 68 310 1.0E-65 T 14-10-2018 IPR035906 MetI-like superfamily MB46_14995 41ede177add35cb7acf592cbc69deb6b 311 SUPERFAMILY SSF161098 72 301 2.75E-56 T 14-10-2018 IPR035906 MetI-like superfamily MB46_18790 09774fe63232375174be0650c23f2c62 540 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 108 130 - T 14-10-2018 IPR023765 Solute-binding protein family 5, conserved site MB46_18790 09774fe63232375174be0650c23f2c62 540 Gene3D G3DSA:3.90.76.10 71 215 4.4E-101 T 14-10-2018 MB46_18790 09774fe63232375174be0650c23f2c62 540 Gene3D G3DSA:3.40.190.10 216 522 4.4E-101 T 14-10-2018 MB46_18790 09774fe63232375174be0650c23f2c62 540 Gene3D G3DSA:3.10.105.10 292 512 4.4E-101 T 14-10-2018 MB46_18790 09774fe63232375174be0650c23f2c62 540 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 103 436 6.2E-75 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain MB46_18790 09774fe63232375174be0650c23f2c62 540 SUPERFAMILY SSF53850 67 535 2.53E-102 T 14-10-2018 MB46_18790 09774fe63232375174be0650c23f2c62 540 PIRSF PIRSF002741 15 533 1.2E-80 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 MB46_05120 d4547a07627d5dca45e21a45a8a33de1 256 Pfam PF01061 ABC-2 type transporter 25 224 1.3E-11 T 14-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 MB46_05120 d4547a07627d5dca45e21a45a8a33de1 256 PIRSF PIRSF006648 4 255 1.1E-19 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 MB46_05750 4295574ac44d905c32e8a1952faa5f37 124 SUPERFAMILY SSF159888 4 113 3.66E-18 T 14-10-2018 MB46_05750 4295574ac44d905c32e8a1952faa5f37 124 Gene3D G3DSA:1.10.10.810 2 113 3.3E-12 T 14-10-2018 MB46_08440 373f5560db8dfc2450e9719d7a8d1d6f 698 Gene3D G3DSA:3.40.50.300 206 355 4.1E-24 T 14-10-2018 MB46_08440 373f5560db8dfc2450e9719d7a8d1d6f 698 Hamap MF_00983 Probable primosomal protein N' [priA]. 34 697 19.316 T 14-10-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 MB46_08440 373f5560db8dfc2450e9719d7a8d1d6f 698 Gene3D G3DSA:1.10.8.630 27 137 3.2E-17 T 14-10-2018 MB46_13085 f2a61262a5ceb27854bfe2d31186caf3 264 Gene3D G3DSA:3.40.50.720 96 263 9.9E-38 T 14-10-2018 MB46_13085 f2a61262a5ceb27854bfe2d31186caf3 264 Gene3D G3DSA:3.40.50.10860 1 95 1.3E-28 T 14-10-2018 MB46_13085 f2a61262a5ceb27854bfe2d31186caf3 264 SUPERFAMILY SSF53223 2 97 5.53E-24 T 14-10-2018 MB46_13085 f2a61262a5ceb27854bfe2d31186caf3 264 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 115 158 1.0E-5 T 14-10-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase MB46_13085 f2a61262a5ceb27854bfe2d31186caf3 264 SUPERFAMILY SSF51735 98 257 1.27E-32 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_13085 f2a61262a5ceb27854bfe2d31186caf3 264 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 17 85 6.8E-15 T 14-10-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 MB46_19740 b84be012fbc724162dd430e69fc0061d 208 SUPERFAMILY SSF46689 2 67 1.03E-9 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MB46_19740 b84be012fbc724162dd430e69fc0061d 208 Pfam PF00440 Bacterial regulatory proteins, tetR family 6 51 1.1E-5 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MB46_19740 b84be012fbc724162dd430e69fc0061d 208 Gene3D G3DSA:1.10.357.10 1 182 3.4E-33 T 14-10-2018 MB46_06055 96328ab83bfd9e3ef2e8dbd356a13fee 644 Pfam PF02720 Domain of unknown function (DUF222) 13 226 1.1E-19 T 14-10-2018 IPR003870 Domain of unknown function DUF222 MB46_06055 96328ab83bfd9e3ef2e8dbd356a13fee 644 Pfam PF01844 HNH endonuclease 465 505 3.1E-5 T 14-10-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 MB46_06055 96328ab83bfd9e3ef2e8dbd356a13fee 644 SMART SM00507 449 501 8.2E-7 T 14-10-2018 IPR003615 HNH nuclease MB46_18785 78d54beb851a70973fbffc1455a639ca 301 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 100 299 7.3E-40 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_18785 78d54beb851a70973fbffc1455a639ca 301 Gene3D G3DSA:1.10.3720.10 71 293 1.4E-24 T 14-10-2018 IPR035906 MetI-like superfamily MB46_18785 78d54beb851a70973fbffc1455a639ca 301 SUPERFAMILY SSF161098 76 285 4.06E-22 T 14-10-2018 IPR035906 MetI-like superfamily MB46_17855 23f19e29f0d214259cbc16a513ccd2c9 177 SUPERFAMILY SSF55729 5 167 3.06E-22 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase MB46_17855 23f19e29f0d214259cbc16a513ccd2c9 177 Pfam PF00583 Acetyltransferase (GNAT) family 44 145 1.3E-10 T 14-10-2018 IPR000182 GNAT domain MB46_17855 23f19e29f0d214259cbc16a513ccd2c9 177 Gene3D G3DSA:3.40.630.30 1 166 2.1E-23 T 14-10-2018 MB46_19775 88f51c9907e7bca15e3b69f8bd21de34 302 Pfam PF05621 Bacterial TniB protein 27 278 1.3E-101 T 14-10-2018 IPR008868 Bacterial TniB MB46_19775 88f51c9907e7bca15e3b69f8bd21de34 302 Gene3D G3DSA:3.40.50.300 18 211 1.9E-17 T 14-10-2018 MB46_19775 88f51c9907e7bca15e3b69f8bd21de34 302 SUPERFAMILY SSF52540 32 280 9.94E-18 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_19095 b017e85f5e6d38230e4842fdc665d82c 874 Pfam PF00343 Carbohydrate phosphorylase 125 170 2.4E-6 T 14-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 MB46_19095 b017e85f5e6d38230e4842fdc665d82c 874 Pfam PF00343 Carbohydrate phosphorylase 275 627 7.7E-20 T 14-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 MB46_19095 b017e85f5e6d38230e4842fdc665d82c 874 Gene3D G3DSA:3.40.50.2000 243 431 3.5E-10 T 14-10-2018 MB46_19095 b017e85f5e6d38230e4842fdc665d82c 874 Gene3D G3DSA:3.40.50.2000 457 667 8.6E-40 T 14-10-2018 MB46_19095 b017e85f5e6d38230e4842fdc665d82c 874 PIRSF PIRSF000460 1 815 3.2E-245 T 14-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 MB46_19095 b017e85f5e6d38230e4842fdc665d82c 874 TIGRFAM TIGR02094 more_P_ylases: alpha-glucan phosphorylases 107 729 2.9E-226 T 14-10-2018 IPR011834 Alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238 MB46_19095 b017e85f5e6d38230e4842fdc665d82c 874 SUPERFAMILY SSF53756 4 762 1.36E-191 T 14-10-2018 MB46_19095 b017e85f5e6d38230e4842fdc665d82c 874 Pfam PF11897 Protein of unknown function (DUF3417) 13 120 7.6E-33 T 14-10-2018 IPR024517 Glycogen phosphorylase, domain of unknown function DUF3417 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238 MB46_19095 b017e85f5e6d38230e4842fdc665d82c 874 Gene3D G3DSA:3.40.50.2000 116 195 3.9E-12 T 14-10-2018 MB46_10275 136db70abf2bd59567971d33f0e589f5 62 Pfam PF12728 Helix-turn-helix domain 9 60 7.2E-10 T 14-10-2018 MB46_10275 136db70abf2bd59567971d33f0e589f5 62 SUPERFAMILY SSF46955 8 60 5.31E-12 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily MB46_11845 5ce0641306544544e3a693d8cccda06f 283 SUPERFAMILY SSF161098 19 266 2.09E-50 T 14-10-2018 IPR035906 MetI-like superfamily MB46_11845 5ce0641306544544e3a693d8cccda06f 283 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 80 261 7.6E-17 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_11845 5ce0641306544544e3a693d8cccda06f 283 Gene3D G3DSA:1.10.3720.10 20 269 9.0E-64 T 14-10-2018 IPR035906 MetI-like superfamily MB46_11845 5ce0641306544544e3a693d8cccda06f 283 TIGRFAM TIGR02141 modB_ABC: molybdate ABC transporter, permease protein 63 263 5.2E-66 T 14-10-2018 IPR011867 Molybdate ABC transporter, permease protein GO:0015098|GO:0015689|GO:0016021 MB46_11845 5ce0641306544544e3a693d8cccda06f 283 TIGRFAM TIGR01581 Mo_ABC_porter: NifC-like ABC-type porter 40 260 6.3E-81 T 14-10-2018 IPR006469 NifC-like ABC-type porter GO:0005215|GO:0016020|GO:0055085 MB46_12435 9cd00fff582f3a4c79ea810c06e8f5c5 279 Gene3D G3DSA:3.40.190.10 136 227 1.5E-68 T 14-10-2018 MB46_12435 9cd00fff582f3a4c79ea810c06e8f5c5 279 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 46 260 4.7E-47 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MB46_12435 9cd00fff582f3a4c79ea810c06e8f5c5 279 SUPERFAMILY SSF53850 34 252 8.8E-56 T 14-10-2018 MB46_12435 9cd00fff582f3a4c79ea810c06e8f5c5 279 SMART SM00062 45 267 5.3E-60 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MB46_12435 9cd00fff582f3a4c79ea810c06e8f5c5 279 Gene3D G3DSA:3.40.190.10 38 260 1.5E-68 T 14-10-2018 MB46_02195 c1cd0d0f45b8b9282b1af6ecf3a4066e 213 SUPERFAMILY SSF53056 9 205 9.03E-54 T 14-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 MB46_02195 c1cd0d0f45b8b9282b1af6ecf3a4066e 213 SMART SM00947 46 206 3.6E-50 T 14-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 MB46_02195 c1cd0d0f45b8b9282b1af6ecf3a4066e 213 Pfam PF00484 Carbonic anhydrase 53 201 7.2E-38 T 14-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 MB46_02195 c1cd0d0f45b8b9282b1af6ecf3a4066e 213 ProSitePatterns PS00704 Prokaryotic-type carbonic anhydrases signature 1. 58 65 - T 14-10-2018 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 MB46_02195 c1cd0d0f45b8b9282b1af6ecf3a4066e 213 Gene3D G3DSA:3.40.1050.10 4 211 9.4E-70 T 14-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 MB46_12350 40104e620dc0174c4693430677fd1744 282 Pfam PF02811 PHP domain 4 68 5.7E-9 T 14-10-2018 IPR004013 PHP domain GO:0003824 MB46_12350 40104e620dc0174c4693430677fd1744 282 SUPERFAMILY SSF89550 2 257 4.9E-43 T 14-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 MB46_12350 40104e620dc0174c4693430677fd1744 282 Gene3D G3DSA:1.10.150.650 99 168 1.4E-29 T 14-10-2018 MB46_12350 40104e620dc0174c4693430677fd1744 282 SMART SM00481 3 68 1.3E-16 T 14-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal MB46_04820 1caf5280fcaee0b789ae796c721112d7 876 Gene3D G3DSA:3.40.50.300 28 203 4.9E-51 T 14-10-2018 MB46_04820 1caf5280fcaee0b789ae796c721112d7 876 Pfam PF08482 ATP-dependent helicase C-terminal 728 863 4.5E-49 T 14-10-2018 IPR013689 ATP-dependent RNA helicase HrpB, C-terminal MB46_04820 1caf5280fcaee0b789ae796c721112d7 876 SMART SM00847 426 518 4.2E-12 T 14-10-2018 IPR007502 Helicase-associated domain GO:0004386 MB46_04820 1caf5280fcaee0b789ae796c721112d7 876 PIRSF PIRSF005496 16 876 3.0E-258 T 14-10-2018 MB46_04820 1caf5280fcaee0b789ae796c721112d7 876 ProSitePatterns PS00690 DEAH-box subfamily ATP-dependent helicases signature. 138 147 - T 14-10-2018 IPR002464 DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site MB46_04820 1caf5280fcaee0b789ae796c721112d7 876 SUPERFAMILY SSF52540 39 375 2.45E-42 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_04820 1caf5280fcaee0b789ae796c721112d7 876 Pfam PF00271 Helicase conserved C-terminal domain 248 366 6.8E-11 T 14-10-2018 IPR001650 Helicase, C-terminal MB46_04820 1caf5280fcaee0b789ae796c721112d7 876 Pfam PF00270 DEAD/DEAH box helicase 35 179 1.3E-8 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MB46_04820 1caf5280fcaee0b789ae796c721112d7 876 Gene3D G3DSA:3.40.50.300 206 383 1.2E-36 T 14-10-2018 MB46_04820 1caf5280fcaee0b789ae796c721112d7 876 Gene3D G3DSA:1.20.120.1080 413 496 2.3E-12 T 14-10-2018 MB46_04820 1caf5280fcaee0b789ae796c721112d7 876 TIGRFAM TIGR01970 DEAH_box_HrpB: ATP-dependent helicase HrpB 23 875 3.2E-204 T 14-10-2018 IPR010225 ATP-dependent helicase HrpB GO:0008026 MB46_04820 1caf5280fcaee0b789ae796c721112d7 876 SMART SM00490 264 366 1.6E-13 T 14-10-2018 IPR001650 Helicase, C-terminal MB46_04820 1caf5280fcaee0b789ae796c721112d7 876 SMART SM00487 4 211 1.3E-15 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MB46_04820 1caf5280fcaee0b789ae796c721112d7 876 Pfam PF04408 Helicase associated domain (HA2) 427 483 1.1E-9 T 14-10-2018 IPR007502 Helicase-associated domain GO:0004386 MB46_13110 c98dad7873e1a6ba878c1b8403187043 202 Gene3D G3DSA:1.10.357.10 15 199 7.7E-39 T 14-10-2018 MB46_13110 c98dad7873e1a6ba878c1b8403187043 202 SUPERFAMILY SSF48498 86 195 3.34E-20 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily MB46_13110 c98dad7873e1a6ba878c1b8403187043 202 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 108 196 8.5E-11 T 14-10-2018 IPR039538 BetI-type transcriptional repressor, C-terminal MB46_13110 c98dad7873e1a6ba878c1b8403187043 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 71 1.1E-14 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MB46_13110 c98dad7873e1a6ba878c1b8403187043 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 46 69 8.3E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MB46_13110 c98dad7873e1a6ba878c1b8403187043 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 25 38 8.3E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MB46_13110 c98dad7873e1a6ba878c1b8403187043 202 SUPERFAMILY SSF46689 12 76 3.44E-16 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MB46_13705 06bcf6b8243771aea12499f5d28282c2 373 Pfam PF06224 Winged helix DNA-binding domain 33 370 1.1E-57 T 14-10-2018 IPR009351 Protein of unknown function DUF1006 MB46_19035 f1efef878f86f4988a6830cecd20369c 288 Gene3D G3DSA:3.40.50.150 3 207 2.5E-7 T 14-10-2018 MB46_19035 f1efef878f86f4988a6830cecd20369c 288 SUPERFAMILY SSF53335 33 188 3.09E-10 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MB46_14250 731e3905222249cc3c9ceed9b4180694 237 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 49 212 4.7E-38 T 14-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 MB46_14250 731e3905222249cc3c9ceed9b4180694 237 SUPERFAMILY SSF52402 27 201 5.72E-38 T 14-10-2018 MB46_14250 731e3905222249cc3c9ceed9b4180694 237 PIRSF PIRSF000857 2 237 1.0E-82 T 14-10-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 MB46_14250 731e3905222249cc3c9ceed9b4180694 237 TIGRFAM TIGR00434 cysH: phosophoadenylyl-sulfate reductase 29 236 6.1E-55 T 14-10-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 MB46_14250 731e3905222249cc3c9ceed9b4180694 237 Gene3D G3DSA:3.40.50.620 7 237 1.1E-62 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MB46_14355 bd0e56588a8dc11b2d66f72701bc7198 232 Pfam PF00753 Metallo-beta-lactamase superfamily 23 212 2.0E-15 T 14-10-2018 IPR001279 Metallo-beta-lactamase MB46_14355 bd0e56588a8dc11b2d66f72701bc7198 232 Gene3D G3DSA:3.60.15.10 2 231 1.9E-40 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MB46_14355 bd0e56588a8dc11b2d66f72701bc7198 232 SMART SM00849 23 212 4.3E-16 T 14-10-2018 IPR001279 Metallo-beta-lactamase MB46_14355 bd0e56588a8dc11b2d66f72701bc7198 232 SUPERFAMILY SSF56281 2 230 1.11E-37 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MB46_04600 6a02b363c9ca17581bd07565a86fb3b9 131 Pfam PF09685 Domain of unknown function (DUF4870) 22 128 1.1E-16 T 14-10-2018 IPR019109 Protein of unknown function DUF4870 MB46_13115 984e60f62085ea3065d44379753c036c 447 SUPERFAMILY SSF53850 23 431 5.43E-52 T 14-10-2018 MB46_13115 984e60f62085ea3065d44379753c036c 447 Gene3D G3DSA:3.40.190.10 157 419 2.7E-93 T 14-10-2018 MB46_13115 984e60f62085ea3065d44379753c036c 447 Pfam PF10518 TAT (twin-arginine translocation) pathway signal sequence 3 27 3.7E-5 T 14-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal MB46_13115 984e60f62085ea3065d44379753c036c 447 Pfam PF01547 Bacterial extracellular solute-binding protein 60 341 4.3E-30 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein MB46_13115 984e60f62085ea3065d44379753c036c 447 Gene3D G3DSA:3.40.190.10 64 363 2.7E-93 T 14-10-2018 MB46_08545 1ef1d680cfa8237e150dca1e43e58e3b 450 Hamap MF_02065 Endolytic murein transglycosylase [mltG]. 106 440 24.085 T 14-10-2018 IPR003770 Endolytic murein transglycosylase MB46_08545 1ef1d680cfa8237e150dca1e43e58e3b 450 Gene3D G3DSA:1.10.8.1150 143 214 2.2E-6 T 14-10-2018 MB46_08545 1ef1d680cfa8237e150dca1e43e58e3b 450 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 133 442 3.6E-33 T 14-10-2018 IPR003770 Endolytic murein transglycosylase MB46_08545 1ef1d680cfa8237e150dca1e43e58e3b 450 Pfam PF02618 YceG-like family 149 437 1.1E-52 T 14-10-2018 IPR003770 Endolytic murein transglycosylase MB46_09480 93c5680a744dbfd378e0975d8cea8299 353 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 13 352 58.842 T 14-10-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 MB46_09480 93c5680a744dbfd378e0975d8cea8299 353 Gene3D G3DSA:3.40.47.10 3 180 1.6E-66 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 MB46_09480 93c5680a744dbfd378e0975d8cea8299 353 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 262 351 6.0E-25 T 14-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 MB46_09480 93c5680a744dbfd378e0975d8cea8299 353 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 118 195 1.3E-25 T 14-10-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 MB46_09480 93c5680a744dbfd378e0975d8cea8299 353 Gene3D G3DSA:3.40.47.10 181 353 5.6E-46 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 MB46_09480 93c5680a744dbfd378e0975d8cea8299 353 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 15 351 2.1E-96 T 14-10-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 MB46_09480 93c5680a744dbfd378e0975d8cea8299 353 SUPERFAMILY SSF53901 14 352 5.34E-58 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 MB46_06450 5e2715a7258efb42e9420ecab4fedbc1 585 SMART SM00382 339 540 1.4E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_06450 5e2715a7258efb42e9420ecab4fedbc1 585 SUPERFAMILY SSF161098 71 256 6.05E-17 T 14-10-2018 IPR035906 MetI-like superfamily MB46_06450 5e2715a7258efb42e9420ecab4fedbc1 585 Gene3D G3DSA:3.40.50.300 308 583 1.8E-80 T 14-10-2018 MB46_06450 5e2715a7258efb42e9420ecab4fedbc1 585 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 94 274 1.8E-14 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_06450 5e2715a7258efb42e9420ecab4fedbc1 585 SUPERFAMILY SSF52540 310 559 7.59E-62 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_06450 5e2715a7258efb42e9420ecab4fedbc1 585 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 540 572 2.9E-6 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MB46_06450 5e2715a7258efb42e9420ecab4fedbc1 585 Pfam PF00005 ABC transporter 331 488 5.4E-23 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_06450 5e2715a7258efb42e9420ecab4fedbc1 585 ProSitePatterns PS00211 ABC transporters family signature. 461 475 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_06450 5e2715a7258efb42e9420ecab4fedbc1 585 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 6 44 5.2E-5 T 14-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain MB46_06450 5e2715a7258efb42e9420ecab4fedbc1 585 Gene3D G3DSA:1.10.3720.10 66 276 6.9E-14 T 14-10-2018 IPR035906 MetI-like superfamily MB46_18935 5448c12bfea2e2aba32f8d1470c9d931 646 SUPERFAMILY SSF51905 5 243 7.25E-10 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_18935 5448c12bfea2e2aba32f8d1470c9d931 646 Pfam PF13454 FAD-NAD(P)-binding 7 186 7.6E-44 T 14-10-2018 IPR038732 FAD-dependent urate hydroxylase HpyO, FAD/NAD(P)-binding domain MB46_18935 5448c12bfea2e2aba32f8d1470c9d931 646 Gene3D G3DSA:3.50.50.60 109 265 5.0E-6 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_17165 5df2a220f02ea9ccc6fe4f0d314adf74 133 Pfam PF03733 Inner membrane component domain 4 54 2.5E-19 T 14-10-2018 IPR005185 Inner membrane component domain MB46_17165 5df2a220f02ea9ccc6fe4f0d314adf74 133 Pfam PF03733 Inner membrane component domain 69 119 1.5E-14 T 14-10-2018 IPR005185 Inner membrane component domain MB46_17165 5df2a220f02ea9ccc6fe4f0d314adf74 133 PIRSF PIRSF028777 1 130 3.3E-50 T 14-10-2018 IPR031308 Uncharacterised conserved protein UCP028777 MB46_11265 f9b086e8584629b6fbbdd6473fecdcb1 416 TIGRFAM TIGR01197 nramp: metal ion transporter, metal ion (Mn2+/Fe2+) transporter (Nramp) family 18 380 5.2E-84 T 14-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 MB46_11265 f9b086e8584629b6fbbdd6473fecdcb1 416 PRINTS PR00447 Natural resistance-associated macrophage protein signature 199 222 2.0E-28 T 14-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 MB46_11265 f9b086e8584629b6fbbdd6473fecdcb1 416 PRINTS PR00447 Natural resistance-associated macrophage protein signature 96 122 2.0E-28 T 14-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 MB46_11265 f9b086e8584629b6fbbdd6473fecdcb1 416 PRINTS PR00447 Natural resistance-associated macrophage protein signature 150 171 2.0E-28 T 14-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 MB46_11265 f9b086e8584629b6fbbdd6473fecdcb1 416 PRINTS PR00447 Natural resistance-associated macrophage protein signature 356 375 2.0E-28 T 14-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 MB46_11265 f9b086e8584629b6fbbdd6473fecdcb1 416 PRINTS PR00447 Natural resistance-associated macrophage protein signature 124 143 2.0E-28 T 14-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 MB46_11265 f9b086e8584629b6fbbdd6473fecdcb1 416 Pfam PF01566 Natural resistance-associated macrophage protein 37 385 1.8E-108 T 14-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 MB46_14325 82adf390c8c7c3655fa2453305c13b87 267 Gene3D G3DSA:3.40.50.300 16 266 1.1E-73 T 14-10-2018 MB46_14325 82adf390c8c7c3655fa2453305c13b87 267 Pfam PF00005 ABC transporter 34 192 3.7E-33 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_14325 82adf390c8c7c3655fa2453305c13b87 267 PIRSF PIRSF039085 15 267 5.9E-120 T 14-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 MB46_14325 82adf390c8c7c3655fa2453305c13b87 267 SMART SM00382 43 248 7.6E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_14325 82adf390c8c7c3655fa2453305c13b87 267 ProSitePatterns PS00211 ABC transporters family signature. 164 178 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_14325 82adf390c8c7c3655fa2453305c13b87 267 SUPERFAMILY SSF52540 18 262 3.84E-78 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_01665 bb952a17e070b31d1313e27c2014a9e2 515 SUPERFAMILY SSF56601 6 369 1.4E-57 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like MB46_01665 bb952a17e070b31d1313e27c2014a9e2 515 Gene3D G3DSA:3.40.710.10 3 369 4.1E-66 T 14-10-2018 MB46_01665 bb952a17e070b31d1313e27c2014a9e2 515 Pfam PF00144 Beta-lactamase 10 366 2.4E-47 T 14-10-2018 IPR001466 Beta-lactamase-related MB46_07050 c6761c29493e736faabdc14425b7334a 469 Gene3D G3DSA:3.40.309.10 249 439 1.7E-157 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 MB46_07050 c6761c29493e736faabdc14425b7334a 469 SUPERFAMILY SSF53720 14 461 1.57E-144 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 MB46_07050 c6761c29493e736faabdc14425b7334a 469 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 270 281 - T 14-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 MB46_07050 c6761c29493e736faabdc14425b7334a 469 Gene3D G3DSA:3.40.605.10 17 461 1.7E-157 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 MB46_07050 c6761c29493e736faabdc14425b7334a 469 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 242 249 - T 14-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 MB46_07050 c6761c29493e736faabdc14425b7334a 469 Pfam PF00171 Aldehyde dehydrogenase family 17 460 5.9E-142 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 MB46_01890 4caab5b09598633f8146e944d234010a 280 Gene3D G3DSA:3.60.10.10 8 280 1.1E-62 T 14-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily MB46_01890 4caab5b09598633f8146e944d234010a 280 SUPERFAMILY SSF56219 10 279 1.7E-62 T 14-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily MB46_01890 4caab5b09598633f8146e944d234010a 280 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 10 278 4.6E-54 T 14-10-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 MB46_01890 4caab5b09598633f8146e944d234010a 280 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 13 271 1.5E-13 T 14-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase MB46_19750 44c1bd793e734d09c55faf834488662c 199 SUPERFAMILY SSF53335 5 182 2.13E-32 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MB46_19750 44c1bd793e734d09c55faf834488662c 199 Pfam PF13649 Methyltransferase domain 46 136 3.6E-17 T 14-10-2018 MB46_19750 44c1bd793e734d09c55faf834488662c 199 Gene3D G3DSA:3.40.50.150 3 198 8.3E-53 T 14-10-2018 MB46_06960 b2676483ade87425e84fa37b234c86e0 418 SMART SM00155 163 190 0.084 T 14-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 MB46_06960 b2676483ade87425e84fa37b234c86e0 418 SMART SM00155 331 358 8.7 T 14-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 MB46_06960 b2676483ade87425e84fa37b234c86e0 418 Pfam PF13091 PLD-like domain 259 383 2.5E-29 T 14-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 MB46_06960 b2676483ade87425e84fa37b234c86e0 418 Pfam PF13091 PLD-like domain 81 205 5.7E-10 T 14-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 MB46_06960 b2676483ade87425e84fa37b234c86e0 418 PIRSF PIRSF000850 321 406 110.0 T 14-10-2018 MB46_06960 b2676483ade87425e84fa37b234c86e0 418 PIRSF PIRSF000850 57 130 4.6E-5 T 14-10-2018 MB46_06960 b2676483ade87425e84fa37b234c86e0 418 PIRSF PIRSF000850 250 311 15.0 T 14-10-2018 MB46_06960 b2676483ade87425e84fa37b234c86e0 418 Gene3D G3DSA:3.30.870.10 249 388 5.4E-30 T 14-10-2018 MB46_06960 b2676483ade87425e84fa37b234c86e0 418 SUPERFAMILY SSF56024 61 228 1.1E-36 T 14-10-2018 MB46_06960 b2676483ade87425e84fa37b234c86e0 418 SUPERFAMILY SSF56024 227 404 2.69E-42 T 14-10-2018 MB46_06960 b2676483ade87425e84fa37b234c86e0 418 Gene3D G3DSA:3.30.870.10 58 238 3.0E-35 T 14-10-2018 MB46_10540 9e0256b70d5fedfc27735cbf07034684 341 TIGRFAM TIGR01098 3A0109s03R: phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein 40 301 7.2E-40 T 14-10-2018 IPR005770 Phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein GO:0043190|GO:0055085 MB46_10540 9e0256b70d5fedfc27735cbf07034684 341 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 62 326 3.0E-50 T 14-10-2018 MB46_10540 9e0256b70d5fedfc27735cbf07034684 341 SUPERFAMILY SSF53850 57 325 1.8E-22 T 14-10-2018 MB46_10540 9e0256b70d5fedfc27735cbf07034684 341 Gene3D G3DSA:3.40.190.10 143 276 5.1E-41 T 14-10-2018 MB46_10540 9e0256b70d5fedfc27735cbf07034684 341 Gene3D G3DSA:3.40.190.10 62 307 5.1E-41 T 14-10-2018 MB46_04040 37b8c1f9e47c7f5dcf48b95b66122c1b 499 Gene3D G3DSA:3.40.50.12780 2 396 2.4E-124 T 14-10-2018 MB46_04040 37b8c1f9e47c7f5dcf48b95b66122c1b 499 Pfam PF00501 AMP-binding enzyme 11 399 1.9E-106 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 MB46_04040 37b8c1f9e47c7f5dcf48b95b66122c1b 499 Gene3D G3DSA:3.30.300.310 397 498 1.1E-31 T 14-10-2018 MB46_04040 37b8c1f9e47c7f5dcf48b95b66122c1b 499 ProSitePatterns PS00455 Putative AMP-binding domain signature. 155 166 - T 14-10-2018 IPR020845 AMP-binding, conserved site MB46_04040 37b8c1f9e47c7f5dcf48b95b66122c1b 499 SUPERFAMILY SSF56801 3 496 1.57E-157 T 14-10-2018 MB46_04040 37b8c1f9e47c7f5dcf48b95b66122c1b 499 Pfam PF13193 AMP-binding enzyme C-terminal domain 409 490 2.5E-21 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain MB46_09130 de15835dfe8954e24451beff5c9e35f9 301 Pfam PF13622 Thioesterase-like superfamily 45 292 4.8E-57 T 14-10-2018 MB46_09130 de15835dfe8954e24451beff5c9e35f9 301 Gene3D G3DSA:3.10.129.90 8 294 1.4E-97 T 14-10-2018 MB46_09130 de15835dfe8954e24451beff5c9e35f9 301 SUPERFAMILY SSF54637 27 126 1.99E-31 T 14-10-2018 IPR029069 HotDog domain superfamily MB46_09130 de15835dfe8954e24451beff5c9e35f9 301 SUPERFAMILY SSF54637 128 295 1.46E-49 T 14-10-2018 IPR029069 HotDog domain superfamily MB46_09930 6ac68e32d3abc69600035cf7892fd4ca 445 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 8 428 1.9E-57 T 14-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 MB46_09930 6ac68e32d3abc69600035cf7892fd4ca 445 SUPERFAMILY SSF55205 5 437 8.83E-109 T 14-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 MB46_09930 6ac68e32d3abc69600035cf7892fd4ca 445 Gene3D G3DSA:3.65.10.10 22 235 9.4E-137 T 14-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 MB46_09930 6ac68e32d3abc69600035cf7892fd4ca 445 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 2 438 34.738 T 14-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MB46_09930 6ac68e32d3abc69600035cf7892fd4ca 445 Gene3D G3DSA:3.65.10.10 7 434 9.4E-137 T 14-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 MB46_09930 6ac68e32d3abc69600035cf7892fd4ca 445 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 4 434 5.2E-129 T 14-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MB46_17660 a934eee108c59f21cbce300f0355d94a 433 Gene3D G3DSA:3.40.190.10 147 426 1.5E-119 T 14-10-2018 MB46_17660 a934eee108c59f21cbce300f0355d94a 433 Pfam PF13416 Bacterial extracellular solute-binding protein 58 360 3.5E-27 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein MB46_17660 a934eee108c59f21cbce300f0355d94a 433 SUPERFAMILY SSF53850 24 431 2.92E-55 T 14-10-2018 MB46_17660 a934eee108c59f21cbce300f0355d94a 433 Gene3D G3DSA:3.40.190.10 41 378 1.5E-119 T 14-10-2018 MB46_16695 26b413018a20fc13c1e3cf99f1eb147b 249 Gene3D G3DSA:1.10.3720.10 36 227 4.0E-25 T 14-10-2018 IPR035906 MetI-like superfamily MB46_16695 26b413018a20fc13c1e3cf99f1eb147b 249 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 56 226 6.9E-18 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_16695 26b413018a20fc13c1e3cf99f1eb147b 249 SUPERFAMILY SSF161098 38 217 2.35E-29 T 14-10-2018 IPR035906 MetI-like superfamily MB46_15355 3e821045d8da85c8100d8180c2b473cb 245 Gene3D G3DSA:3.10.180.10 129 245 2.2E-25 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MB46_15355 3e821045d8da85c8100d8180c2b473cb 245 Gene3D G3DSA:3.10.180.10 1 128 6.5E-19 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MB46_15355 3e821045d8da85c8100d8180c2b473cb 245 SUPERFAMILY SSF54593 2 125 7.61E-12 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MB46_15355 3e821045d8da85c8100d8180c2b473cb 245 SUPERFAMILY SSF54593 132 244 6.91E-13 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MB46_19020 7b83af8c90748fd57c44196d5cca9b74 392 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 15 385 3.6E-99 T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 MB46_19020 7b83af8c90748fd57c44196d5cca9b74 392 PIRSF PIRSF001434 1 389 1.3E-113 T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 MB46_19020 7b83af8c90748fd57c44196d5cca9b74 392 Gene3D G3DSA:3.40.640.10 10 261 2.2E-66 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MB46_19020 7b83af8c90748fd57c44196d5cca9b74 392 SUPERFAMILY SSF53383 22 387 2.04E-88 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MB46_19020 7b83af8c90748fd57c44196d5cca9b74 392 Gene3D G3DSA:3.90.1150.10 262 392 1.4E-39 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MB46_12125 38254516d98c8273441ed2f3235a0c23 226 SUPERFAMILY SSF51391 18 221 1.57E-54 T 14-10-2018 IPR036206 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 MB46_12125 38254516d98c8273441ed2f3235a0c23 226 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 21 223 23.118 T 14-10-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 MB46_12125 38254516d98c8273441ed2f3235a0c23 226 Gene3D G3DSA:3.20.20.70 16 223 3.0E-59 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MB46_12125 38254516d98c8273441ed2f3235a0c23 226 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 23 218 4.4E-54 T 14-10-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 MB46_12125 38254516d98c8273441ed2f3235a0c23 226 Pfam PF02581 Thiamine monophosphate synthase 24 205 1.3E-46 T 14-10-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 MB46_09330 defc6afc67528609d83d97b96e86e0d5 198 Hamap MF_00045 Oligoribonuclease [orn]. 3 182 36.919 T 14-10-2018 IPR022894 Oligoribonuclease GO:0000175 MB46_09330 defc6afc67528609d83d97b96e86e0d5 198 SMART SM00479 7 181 8.9E-25 T 14-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III MB46_09330 defc6afc67528609d83d97b96e86e0d5 198 Pfam PF00929 Exonuclease 9 171 1.0E-25 T 14-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III MB46_09330 defc6afc67528609d83d97b96e86e0d5 198 SUPERFAMILY SSF53098 5 180 3.73E-39 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily MB46_09330 defc6afc67528609d83d97b96e86e0d5 198 Gene3D G3DSA:3.30.420.10 2 183 8.6E-67 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 MB46_15140 4a8e2debe78dc08fba5a95e4c5c64ea6 221 Gene3D G3DSA:3.50.50.60 28 165 5.3E-9 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_15140 4a8e2debe78dc08fba5a95e4c5c64ea6 221 SUPERFAMILY SSF51905 35 161 1.87E-13 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_01400 599175cca9383dc5e7fa3672d132ec27 396 SUPERFAMILY SSF51658 5 395 3.73E-108 T 14-10-2018 IPR036237 Xylose isomerase-like superfamily MB46_01400 599175cca9383dc5e7fa3672d132ec27 396 Hamap MF_00455 Xylose isomerase [xylA]. 1 392 34.562 T 14-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 MB46_01400 599175cca9383dc5e7fa3672d132ec27 396 PRINTS PR00688 Xylose isomerase signature 129 150 3.3E-65 T 14-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 MB46_01400 599175cca9383dc5e7fa3672d132ec27 396 PRINTS PR00688 Xylose isomerase signature 178 202 3.3E-65 T 14-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 MB46_01400 599175cca9383dc5e7fa3672d132ec27 396 PRINTS PR00688 Xylose isomerase signature 220 247 3.3E-65 T 14-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 MB46_01400 599175cca9383dc5e7fa3672d132ec27 396 PRINTS PR00688 Xylose isomerase signature 45 67 3.3E-65 T 14-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 MB46_01400 599175cca9383dc5e7fa3672d132ec27 396 PRINTS PR00688 Xylose isomerase signature 287 298 3.3E-65 T 14-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 MB46_01400 599175cca9383dc5e7fa3672d132ec27 396 PRINTS PR00688 Xylose isomerase signature 82 102 3.3E-65 T 14-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 MB46_01400 599175cca9383dc5e7fa3672d132ec27 396 PRINTS PR00688 Xylose isomerase signature 156 175 3.3E-65 T 14-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 MB46_01400 599175cca9383dc5e7fa3672d132ec27 396 PRINTS PR00688 Xylose isomerase signature 248 259 3.3E-65 T 14-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 MB46_01400 599175cca9383dc5e7fa3672d132ec27 396 PRINTS PR00688 Xylose isomerase signature 105 124 3.3E-65 T 14-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 MB46_01400 599175cca9383dc5e7fa3672d132ec27 396 TIGRFAM TIGR02631 xylA_Arthro: xylose isomerase 3 393 1.2E-201 T 14-10-2018 IPR013453 Xylose isomerase, actinobacteria GO:0009045|GO:0042732 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 MB46_01400 599175cca9383dc5e7fa3672d132ec27 396 Pfam PF01261 Xylose isomerase-like TIM barrel 42 265 9.8E-26 T 14-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain MB46_01400 599175cca9383dc5e7fa3672d132ec27 396 Gene3D G3DSA:3.20.20.150 2 396 6.3E-137 T 14-10-2018 MB46_19735 5f5aa3bbe58e8f0a5e7448327e885a1e 148 SUPERFAMILY SSF54593 10 133 1.14E-16 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MB46_19735 5f5aa3bbe58e8f0a5e7448327e885a1e 148 Gene3D G3DSA:3.10.180.10 4 143 4.7E-52 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MB46_14975 672294515234960cd1ec2a524a20a8f1 325 Gene3D G3DSA:3.40.1190.20 4 320 1.9E-82 T 14-10-2018 IPR029056 Ribokinase-like MB46_14975 672294515234960cd1ec2a524a20a8f1 325 Pfam PF00294 pfkB family carbohydrate kinase 8 307 1.4E-50 T 14-10-2018 IPR011611 Carbohydrate kinase PfkB MB46_14975 672294515234960cd1ec2a524a20a8f1 325 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 260 273 - T 14-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 MB46_14975 672294515234960cd1ec2a524a20a8f1 325 SUPERFAMILY SSF53613 1 312 8.73E-69 T 14-10-2018 IPR029056 Ribokinase-like MB46_17705 455536468e958013db0ef0263161a8ca 258 SUPERFAMILY SSF51182 11 101 2.55E-13 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily MB46_17705 455536468e958013db0ef0263161a8ca 258 Gene3D G3DSA:2.60.120.10 4 113 9.2E-12 T 14-10-2018 IPR014710 RmlC-like jelly roll fold MB46_17705 455536468e958013db0ef0263161a8ca 258 Pfam PF07883 Cupin domain 38 99 7.1E-9 T 14-10-2018 IPR013096 Cupin 2, conserved barrel MB46_13620 08932bbd44bb7a503539e9fe8662d072 677 Pfam PF10022 Uncharacterized protein conserved in bacteria (DUF2264) 23 370 2.4E-105 T 14-10-2018 IPR016624 Uncharacterised conserved protein UCP014753 MB46_03280 2b81692b467d8ce09bf2d332162db429 782 TIGRFAM TIGR03061 pip_yhgE_Nterm: YhgE/Pip N-terminal domain 10 171 8.3E-53 T 14-10-2018 IPR017500 Phage infection protein, YhgE, N-terminal MB46_03280 2b81692b467d8ce09bf2d332162db429 782 Pfam PF12698 ABC-2 family transporter protein 560 762 3.2E-8 T 14-10-2018 MB46_03280 2b81692b467d8ce09bf2d332162db429 782 Pfam PF12698 ABC-2 family transporter protein 25 148 5.0E-8 T 14-10-2018 MB46_03280 2b81692b467d8ce09bf2d332162db429 782 TIGRFAM TIGR03062 pip_yhgE_Cterm: YhgE/Pip C-terminal domain 563 769 2.0E-59 T 14-10-2018 IPR017501 Phage infection protein, YhgE, C-terminal MB46_03280 2b81692b467d8ce09bf2d332162db429 782 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 246 272 8.0E-5 T 14-10-2018 IPR023908 xxxLxxG heptad repeat MB46_03280 2b81692b467d8ce09bf2d332162db429 782 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 239 265 1.8E-4 T 14-10-2018 IPR023908 xxxLxxG heptad repeat MB46_03280 2b81692b467d8ce09bf2d332162db429 782 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 406 430 5.2E-6 T 14-10-2018 IPR023908 xxxLxxG heptad repeat MB46_03280 2b81692b467d8ce09bf2d332162db429 782 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 431 458 3.0E-4 T 14-10-2018 IPR023908 xxxLxxG heptad repeat MB46_03280 2b81692b467d8ce09bf2d332162db429 782 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 424 451 6.2E-6 T 14-10-2018 IPR023908 xxxLxxG heptad repeat MB46_03280 2b81692b467d8ce09bf2d332162db429 782 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 219 244 2.6E-5 T 14-10-2018 IPR023908 xxxLxxG heptad repeat MB46_08895 c07d4d233e55a5eaf06ec58529f50bb0 375 Pfam PF05175 Methyltransferase small domain 199 368 2.0E-46 T 14-10-2018 IPR007848 Methyltransferase small domain GO:0008168 MB46_08895 c07d4d233e55a5eaf06ec58529f50bb0 375 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 301 307 - T 14-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 MB46_08895 c07d4d233e55a5eaf06ec58529f50bb0 375 Gene3D G3DSA:3.40.50.150 5 179 1.5E-47 T 14-10-2018 MB46_08895 c07d4d233e55a5eaf06ec58529f50bb0 375 SUPERFAMILY SSF53335 196 351 4.97E-30 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MB46_08895 c07d4d233e55a5eaf06ec58529f50bb0 375 Gene3D G3DSA:3.40.50.150 193 372 2.5E-50 T 14-10-2018 MB46_00735 ce6e859f40c25871b384b395b81c874f 329 SUPERFAMILY SSF161098 97 309 5.23E-13 T 14-10-2018 IPR035906 MetI-like superfamily MB46_00735 ce6e859f40c25871b384b395b81c874f 329 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 120 326 7.3E-42 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_00735 ce6e859f40c25871b384b395b81c874f 329 Gene3D G3DSA:1.10.3720.10 91 321 5.0E-17 T 14-10-2018 IPR035906 MetI-like superfamily MB46_04495 546c0672e9906757c857eabfcf97d17a 214 Pfam PF00589 Phage integrase family 99 214 5.0E-7 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MB46_04495 546c0672e9906757c857eabfcf97d17a 214 Gene3D G3DSA:1.10.443.10 90 214 6.5E-10 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 MB46_04495 546c0672e9906757c857eabfcf97d17a 214 SUPERFAMILY SSF56349 28 213 9.42E-16 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MB46_03020 4b6c7c0a4186c4da96bdac70120205ad 165 Gene3D G3DSA:3.40.630.30 1 165 3.6E-26 T 14-10-2018 MB46_03020 4b6c7c0a4186c4da96bdac70120205ad 165 SUPERFAMILY SSF55729 1 164 1.89E-29 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase MB46_03020 4b6c7c0a4186c4da96bdac70120205ad 165 Pfam PF00583 Acetyltransferase (GNAT) family 48 141 2.3E-12 T 14-10-2018 IPR000182 GNAT domain MB46_05820 cfa511e1bb57e6f6ef0d29114c369c44 124 Pfam PF03793 PASTA domain 46 112 1.2E-5 T 14-10-2018 IPR005543 PASTA domain MB46_05820 cfa511e1bb57e6f6ef0d29114c369c44 124 Gene3D G3DSA:3.30.10.20 42 113 1.1E-6 T 14-10-2018 MB46_16565 c3cf1a49d4bdf5bb207b664b96f600a7 381 Gene3D G3DSA:3.40.50.970 2 357 2.4E-107 T 14-10-2018 MB46_16565 c3cf1a49d4bdf5bb207b664b96f600a7 381 TIGRFAM TIGR03181 PDH_E1_alph_x: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 11 358 2.3E-126 T 14-10-2018 IPR017596 Pyruvate dehydrogenase E1 component subunit alpha/BCKADH E1-alpha KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 MB46_16565 c3cf1a49d4bdf5bb207b664b96f600a7 381 SUPERFAMILY SSF52518 29 361 6.25E-90 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold MB46_16565 c3cf1a49d4bdf5bb207b664b96f600a7 381 Pfam PF00676 Dehydrogenase E1 component 44 314 4.4E-71 T 14-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 MB46_02945 4eae2458e7a576715c83dcd5192356f0 653 Pfam PF00498 FHA domain 560 642 1.1E-6 T 14-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 MB46_02945 4eae2458e7a576715c83dcd5192356f0 653 SUPERFAMILY SSF49879 554 644 8.29E-10 T 14-10-2018 IPR008984 SMAD/FHA domain superfamily GO:0005515 MB46_02945 4eae2458e7a576715c83dcd5192356f0 653 Gene3D G3DSA:2.60.200.20 543 650 1.1E-11 T 14-10-2018 MB46_17455 89417c79bc4b1150e3c7df32c3b823a0 328 SUPERFAMILY SSF53067 2 125 4.75E-25 T 14-10-2018 MB46_17455 89417c79bc4b1150e3c7df32c3b823a0 328 SUPERFAMILY SSF53067 130 307 2.59E-33 T 14-10-2018 MB46_17455 89417c79bc4b1150e3c7df32c3b823a0 328 Gene3D G3DSA:3.30.420.150 108 293 3.6E-67 T 14-10-2018 MB46_17455 89417c79bc4b1150e3c7df32c3b823a0 328 Pfam PF02541 Ppx/GppA phosphatase family 30 305 2.4E-60 T 14-10-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 MB46_17455 89417c79bc4b1150e3c7df32c3b823a0 328 Gene3D G3DSA:3.30.420.40 5 300 3.6E-67 T 14-10-2018 MB46_16665 aa49f9fbdb1198d31ea6814a649906e4 141 PRINTS PR01438 Universal stress protein signature 116 138 1.1E-11 T 14-10-2018 IPR006015 Universal stress protein A MB46_16665 aa49f9fbdb1198d31ea6814a649906e4 141 PRINTS PR01438 Universal stress protein signature 99 111 1.1E-11 T 14-10-2018 IPR006015 Universal stress protein A MB46_16665 aa49f9fbdb1198d31ea6814a649906e4 141 PRINTS PR01438 Universal stress protein signature 2 20 1.1E-11 T 14-10-2018 IPR006015 Universal stress protein A MB46_16665 aa49f9fbdb1198d31ea6814a649906e4 141 Gene3D G3DSA:3.40.50.620 1 139 1.1E-28 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MB46_16665 aa49f9fbdb1198d31ea6814a649906e4 141 Pfam PF00582 Universal stress protein family 1 138 3.2E-27 T 14-10-2018 IPR006016 UspA MB46_16665 aa49f9fbdb1198d31ea6814a649906e4 141 SUPERFAMILY SSF52402 5 139 8.37E-28 T 14-10-2018 MB46_03825 c243dffc5b42b6e56349f60ccc143c39 362 SMART SM00421 296 353 1.4E-7 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_03825 c243dffc5b42b6e56349f60ccc143c39 362 Pfam PF00196 Bacterial regulatory proteins, luxR family 299 353 2.8E-8 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_03825 c243dffc5b42b6e56349f60ccc143c39 362 SUPERFAMILY SSF46894 287 354 2.28E-11 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MB46_03825 c243dffc5b42b6e56349f60ccc143c39 362 Gene3D G3DSA:1.10.10.10 241 359 3.4E-13 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_13025 6377f63e7a3e00c216d3971d4eb91b6c 688 SUPERFAMILY SSF52266 472 679 2.01E-5 T 14-10-2018 MB46_13025 6377f63e7a3e00c216d3971d4eb91b6c 688 Pfam PF01757 Acyltransferase family 29 357 1.1E-11 T 14-10-2018 IPR002656 Acyltransferase 3 GO:0016747 MB46_03465 eb3d820d23058603132a45cfb71a3399 126 Pfam PF05305 Protein of unknown function (DUF732) 36 121 3.9E-9 T 14-10-2018 IPR007969 Domain of unknown function DUF732 MB46_14105 ddc1e74ade9a199eb18eb31928b109fa 579 Pfam PF13490 Putative zinc-finger 198 231 9.4E-6 T 14-10-2018 IPR027383 Putative zinc-finger MB46_14105 ddc1e74ade9a199eb18eb31928b109fa 579 SUPERFAMILY SSF88946 13 117 4.45E-14 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 MB46_14105 ddc1e74ade9a199eb18eb31928b109fa 579 SUPERFAMILY SSF88659 123 184 1.05E-7 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like MB46_14105 ddc1e74ade9a199eb18eb31928b109fa 579 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 31 185 1.1E-14 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 MB46_14105 ddc1e74ade9a199eb18eb31928b109fa 579 Pfam PF04542 Sigma-70 region 2 35 94 2.2E-8 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 MB46_14105 ddc1e74ade9a199eb18eb31928b109fa 579 Gene3D G3DSA:1.10.1740.10 10 125 6.5E-13 T 14-10-2018 MB46_14105 ddc1e74ade9a199eb18eb31928b109fa 579 Gene3D G3DSA:1.10.10.10 134 188 3.0E-6 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_16445 b6aaae3bde74b13539a1c4967decd659 295 SUPERFAMILY SSF161098 26 295 1.5E-57 T 14-10-2018 IPR035906 MetI-like superfamily MB46_16445 b6aaae3bde74b13539a1c4967decd659 295 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 110 287 1.1E-15 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_16445 b6aaae3bde74b13539a1c4967decd659 295 Gene3D G3DSA:1.10.3720.10 19 287 1.3E-46 T 14-10-2018 IPR035906 MetI-like superfamily MB46_12700 795b282b1660f5dc8b17e03098939a35 340 Pfam PF13377 Periplasmic binding protein-like domain 175 333 9.6E-36 T 14-10-2018 MB46_12700 795b282b1660f5dc8b17e03098939a35 340 Gene3D G3DSA:1.10.260.40 2 62 1.7E-22 T 14-10-2018 MB46_12700 795b282b1660f5dc8b17e03098939a35 340 Gene3D G3DSA:3.40.50.2300 167 293 4.5E-67 T 14-10-2018 MB46_12700 795b282b1660f5dc8b17e03098939a35 340 ProSitePatterns PS00356 LacI-type HTH domain signature. 12 30 - T 14-10-2018 MB46_12700 795b282b1660f5dc8b17e03098939a35 340 SUPERFAMILY SSF53822 68 338 6.89E-58 T 14-10-2018 IPR028082 Periplasmic binding protein-like I MB46_12700 795b282b1660f5dc8b17e03098939a35 340 Gene3D G3DSA:3.40.50.2300 63 310 4.5E-67 T 14-10-2018 MB46_12700 795b282b1660f5dc8b17e03098939a35 340 SMART SM00354 9 79 1.4E-27 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MB46_12700 795b282b1660f5dc8b17e03098939a35 340 SUPERFAMILY SSF47413 10 67 3.94E-18 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MB46_12700 795b282b1660f5dc8b17e03098939a35 340 Pfam PF00356 Bacterial regulatory proteins, lacI family 11 56 2.7E-18 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MB46_18375 994f916500b56c7b3ea40769cd5aca69 157 Gene3D G3DSA:1.10.10.10 4 131 3.8E-16 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_18375 994f916500b56c7b3ea40769cd5aca69 157 SUPERFAMILY SSF46785 21 134 7.86E-16 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_18375 994f916500b56c7b3ea40769cd5aca69 157 Pfam PF09339 IclR helix-turn-helix domain 38 72 1.1E-7 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 MB46_00375 2cca2056638048ded1a8e07f58eb444c 243 SUPERFAMILY SSF63380 51 104 1.09E-7 T 14-10-2018 IPR017938 Riboflavin synthase-like beta-barrel MB46_00375 2cca2056638048ded1a8e07f58eb444c 243 Pfam PF04954 Siderophore-interacting protein 117 232 3.0E-29 T 14-10-2018 IPR007037 Siderophore-interacting protein, C-terminal domain MB46_00375 2cca2056638048ded1a8e07f58eb444c 243 Gene3D G3DSA:2.40.30.10 1 105 5.1E-20 T 14-10-2018 MB46_00375 2cca2056638048ded1a8e07f58eb444c 243 Pfam PF08021 Siderophore-interacting FAD-binding domain 1 101 6.7E-17 T 14-10-2018 IPR013113 FAD-binding 9, siderophore-interacting MB46_00375 2cca2056638048ded1a8e07f58eb444c 243 Gene3D G3DSA:3.40.50.80 111 242 7.7E-33 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain MB46_11090 7e9442e3055f79dc63424b9f61dc4995 352 Gene3D G3DSA:3.10.580.10 199 343 9.8E-30 T 14-10-2018 MB46_11090 7e9442e3055f79dc63424b9f61dc4995 352 Pfam PF01595 Domain of unknown function DUF21 10 200 5.0E-39 T 14-10-2018 IPR002550 CNNM, transmembrane domain MB46_11090 7e9442e3055f79dc63424b9f61dc4995 352 SUPERFAMILY SSF54631 204 338 3.54E-22 T 14-10-2018 MB46_10885 22f971683d9993d597d978529daff118 346 Pfam PF00953 Glycosyl transferase family 4 83 227 6.5E-24 T 14-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 MB46_00035 b7caad71caa52f5e8f61493050e2ee7c 343 SUPERFAMILY SSF53822 62 340 1.85E-55 T 14-10-2018 IPR028082 Periplasmic binding protein-like I MB46_00035 b7caad71caa52f5e8f61493050e2ee7c 343 SUPERFAMILY SSF47413 3 59 8.13E-13 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MB46_00035 b7caad71caa52f5e8f61493050e2ee7c 343 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 46 7.2E-11 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MB46_00035 b7caad71caa52f5e8f61493050e2ee7c 343 Gene3D G3DSA:3.40.50.2300 55 308 2.3E-65 T 14-10-2018 MB46_00035 b7caad71caa52f5e8f61493050e2ee7c 343 Gene3D G3DSA:3.40.50.2300 159 291 2.3E-65 T 14-10-2018 MB46_00035 b7caad71caa52f5e8f61493050e2ee7c 343 SMART SM00354 1 71 7.1E-18 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MB46_00035 b7caad71caa52f5e8f61493050e2ee7c 343 Pfam PF13377 Periplasmic binding protein-like domain 167 337 3.3E-31 T 14-10-2018 MB46_00035 b7caad71caa52f5e8f61493050e2ee7c 343 Gene3D G3DSA:1.10.260.40 2 54 4.8E-15 T 14-10-2018 MB46_07695 7fdf1db556c86bd4e6631042806ddb8f 212 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 9 204 9.8E-71 T 14-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MB46_07695 7fdf1db556c86bd4e6631042806ddb8f 212 SUPERFAMILY SSF55821 7 207 3.66E-77 T 14-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily MB46_07695 7fdf1db556c86bd4e6631042806ddb8f 212 Gene3D G3DSA:3.90.870.10 2 212 4.7E-85 T 14-10-2018 MB46_07695 7fdf1db556c86bd4e6631042806ddb8f 212 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 14 203 3.3E-80 T 14-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MB46_19870 6ffd97cbb169e62ce47458602de2a579 255 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 216 249 4.2E-4 T 14-10-2018 MB46_12320 3f3a8e51b4461b37e7d36b1032102d7a 127 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 4 124 3.1E-32 T 14-10-2018 IPR006056 RidA family Reactome: R-HSA-8849175 MB46_12320 3f3a8e51b4461b37e7d36b1032102d7a 127 Pfam PF01042 Endoribonuclease L-PSP 9 124 3.2E-30 T 14-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 MB46_12320 3f3a8e51b4461b37e7d36b1032102d7a 127 SUPERFAMILY SSF55298 1 126 1.15E-37 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 MB46_12320 3f3a8e51b4461b37e7d36b1032102d7a 127 Gene3D G3DSA:3.30.1330.40 1 126 6.4E-40 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 MB46_09635 b8bc6f47ad7a1297692d2851c3b63f19 221 SUPERFAMILY SSF46894 155 220 2.99E-15 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MB46_09635 b8bc6f47ad7a1297692d2851c3b63f19 221 SMART SM00421 158 215 3.3E-14 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_09635 b8bc6f47ad7a1297692d2851c3b63f19 221 Pfam PF00072 Response regulator receiver domain 26 92 6.2E-5 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MB46_09635 b8bc6f47ad7a1297692d2851c3b63f19 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 161 175 1.0E-8 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_09635 b8bc6f47ad7a1297692d2851c3b63f19 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 175 191 1.0E-8 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_09635 b8bc6f47ad7a1297692d2851c3b63f19 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 191 203 1.0E-8 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_09635 b8bc6f47ad7a1297692d2851c3b63f19 221 SUPERFAMILY SSF52172 7 144 1.61E-11 T 14-10-2018 IPR011006 CheY-like superfamily MB46_09635 b8bc6f47ad7a1297692d2851c3b63f19 221 Pfam PF00196 Bacterial regulatory proteins, luxR family 161 214 2.9E-14 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_09635 b8bc6f47ad7a1297692d2851c3b63f19 221 Gene3D G3DSA:3.40.50.12740 14 221 1.1E-27 T 14-10-2018 MB46_00535 8bff27520920ff3d567ff9d58b83fd32 250 SUPERFAMILY SSF102198 20 249 2.75E-50 T 14-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 MB46_00535 8bff27520920ff3d567ff9d58b83fd32 250 Pfam PF04199 Putative cyclase 24 189 3.8E-31 T 14-10-2018 IPR007325 Kynurenine formamidase/cyclase-like GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 MB46_00535 8bff27520920ff3d567ff9d58b83fd32 250 Gene3D G3DSA:3.50.30.50 13 250 7.2E-61 T 14-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 MB46_02015 75433076726aea2d2444d5d4029d8a07 327 SUPERFAMILY SSF53067 144 323 2.8E-36 T 14-10-2018 MB46_02015 75433076726aea2d2444d5d4029d8a07 327 Gene3D G3DSA:3.30.420.150 141 327 5.7E-58 T 14-10-2018 MB46_02015 75433076726aea2d2444d5d4029d8a07 327 SUPERFAMILY SSF53067 2 139 9.5E-31 T 14-10-2018 MB46_02015 75433076726aea2d2444d5d4029d8a07 327 Gene3D G3DSA:3.30.420.40 1 138 7.4E-42 T 14-10-2018 MB46_02015 75433076726aea2d2444d5d4029d8a07 327 Pfam PF02541 Ppx/GppA phosphatase family 36 298 4.2E-63 T 14-10-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 MB46_14060 4222c4afc4d08c897e916e507bf32bc2 289 Gene3D G3DSA:3.30.2010.10 66 156 2.9E-27 T 14-10-2018 MB46_14060 4222c4afc4d08c897e916e507bf32bc2 289 Hamap MF_00188 Protease HtpX [htpX]. 7 283 26.056 T 14-10-2018 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 MB46_14060 4222c4afc4d08c897e916e507bf32bc2 289 Pfam PF01435 Peptidase family M48 73 283 2.9E-34 T 14-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 MB46_10490 e472364c83e4d6a97f8663bab67ac9f1 499 SUPERFAMILY SSF51905 8 276 9.84E-24 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_10490 e472364c83e4d6a97f8663bab67ac9f1 499 Hamap MF_00212 Probable malate:quinone oxidoreductase [mqo]. 6 494 51.835 T 14-10-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 MB46_10490 e472364c83e4d6a97f8663bab67ac9f1 499 TIGRFAM TIGR01320 mal_quin_oxido: malate dehydrogenase (acceptor) 10 490 3.4E-228 T 14-10-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 MB46_10490 e472364c83e4d6a97f8663bab67ac9f1 499 Pfam PF06039 Malate:quinone oxidoreductase (Mqo) 9 494 1.5E-231 T 14-10-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 MB46_10490 e472364c83e4d6a97f8663bab67ac9f1 499 Gene3D G3DSA:3.50.50.60 12 259 9.5E-11 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_10490 e472364c83e4d6a97f8663bab67ac9f1 499 Gene3D G3DSA:3.30.9.10 115 180 9.5E-11 T 14-10-2018 MB46_12120 50b90b00e18dda5a11b99ef0b5d3ea23 422 SUPERFAMILY SSF51905 11 405 7.12E-34 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_12120 50b90b00e18dda5a11b99ef0b5d3ea23 422 Gene3D G3DSA:3.50.50.60 13 382 2.7E-75 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_12120 50b90b00e18dda5a11b99ef0b5d3ea23 422 SUPERFAMILY SSF54373 245 337 4.71E-13 T 14-10-2018 MB46_12120 50b90b00e18dda5a11b99ef0b5d3ea23 422 Pfam PF01266 FAD dependent oxidoreductase 13 380 9.5E-48 T 14-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 MB46_12120 50b90b00e18dda5a11b99ef0b5d3ea23 422 TIGRFAM TIGR02352 thiamin_ThiO: glycine oxidase ThiO 13 383 1.4E-85 T 14-10-2018 IPR012727 Glycine oxidase ThiO GO:0016491|GO:0050660 KEGG: 00730+1.4.3.19|MetaCyc: PWY-7396|MetaCyc: PWY-7806 MB46_12120 50b90b00e18dda5a11b99ef0b5d3ea23 422 Gene3D G3DSA:3.30.9.10 96 337 2.7E-75 T 14-10-2018 MB46_06360 c371c0f62dfbb49204d742e000bf986a 297 Gene3D G3DSA:1.10.3720.10 90 292 1.9E-18 T 14-10-2018 IPR035906 MetI-like superfamily MB46_06360 c371c0f62dfbb49204d742e000bf986a 297 SUPERFAMILY SSF161098 93 281 7.98E-25 T 14-10-2018 IPR035906 MetI-like superfamily MB46_06360 c371c0f62dfbb49204d742e000bf986a 297 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 118 289 2.2E-24 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_02110 a576119c4d370f11015730e71b2c8fb1 354 Gene3D G3DSA:2.40.420.20 260 332 2.7E-14 T 14-10-2018 MB46_02110 a576119c4d370f11015730e71b2c8fb1 354 SUPERFAMILY SSF111369 60 156 3.53E-5 T 14-10-2018 MB46_08035 5d6e6b9e0f79ee237724cfb5e41e038b 452 Gene3D G3DSA:1.20.1250.20 2 415 3.7E-44 T 14-10-2018 MB46_08035 5d6e6b9e0f79ee237724cfb5e41e038b 452 Pfam PF07690 Major Facilitator Superfamily 15 359 3.9E-31 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MB46_08035 5d6e6b9e0f79ee237724cfb5e41e038b 452 SUPERFAMILY SSF103473 3 413 1.07E-50 T 14-10-2018 IPR036259 MFS transporter superfamily MB46_06555 f98be0708202b9513625482577549781 295 SUPERFAMILY SSF161098 9 294 5.05E-52 T 14-10-2018 IPR035906 MetI-like superfamily MB46_06555 f98be0708202b9513625482577549781 295 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 94 286 4.3E-15 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_06555 f98be0708202b9513625482577549781 295 Gene3D G3DSA:1.10.3720.10 3 286 1.6E-67 T 14-10-2018 IPR035906 MetI-like superfamily MB46_04915 29b413a1f7d471b625330ce564fb8a2b 356 SUPERFAMILY SSF51679 27 350 1.96E-74 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 MB46_04915 29b413a1f7d471b625330ce564fb8a2b 356 Pfam PF00296 Luciferase-like monooxygenase 25 314 1.6E-46 T 14-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MB46_04915 29b413a1f7d471b625330ce564fb8a2b 356 Gene3D G3DSA:3.20.20.30 8 355 3.7E-84 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 MB46_04915 29b413a1f7d471b625330ce564fb8a2b 356 TIGRFAM TIGR03858 LLM_2I7G: probable oxidoreductase, LLM family 16 350 4.7E-156 T 14-10-2018 IPR022290 Conserved hypothetical protein CHP03858, luciferase-like monooxygenase, putative MB46_19430 08593471b8bf09d06c995928b77e4911 611 SUPERFAMILY SSF88946 13 115 2.75E-16 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 MB46_19430 08593471b8bf09d06c995928b77e4911 611 Gene3D G3DSA:1.10.10.10 129 186 4.0E-9 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_19430 08593471b8bf09d06c995928b77e4911 611 Pfam PF08281 Sigma-70, region 4 131 177 1.1E-6 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MB46_19430 08593471b8bf09d06c995928b77e4911 611 SUPERFAMILY SSF88659 130 181 3.36E-9 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like MB46_19430 08593471b8bf09d06c995928b77e4911 611 Gene3D G3DSA:2.60.40.10 442 516 8.2E-6 T 14-10-2018 IPR013783 Immunoglobulin-like fold MB46_19430 08593471b8bf09d06c995928b77e4911 611 Pfam PF04542 Sigma-70 region 2 36 90 3.7E-7 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 MB46_19430 08593471b8bf09d06c995928b77e4911 611 Gene3D G3DSA:1.10.1740.10 9 126 1.5E-15 T 14-10-2018 MB46_19430 08593471b8bf09d06c995928b77e4911 611 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 30 181 7.0E-16 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 MB46_01545 5cfb58e9891df1068f7191ec2e696060 235 SUPERFAMILY SSF53474 3 219 3.62E-24 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_01545 5cfb58e9891df1068f7191ec2e696060 235 Gene3D G3DSA:3.40.50.1820 1 224 2.0E-38 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_01545 5cfb58e9891df1068f7191ec2e696060 235 Pfam PF12697 Alpha/beta hydrolase family 4 216 1.8E-17 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MB46_05730 0d80a94c5feefed19cbbb954cd05fbe6 309 Gene3D G3DSA:1.10.3720.10 67 308 1.1E-49 T 14-10-2018 IPR035906 MetI-like superfamily MB46_05730 0d80a94c5feefed19cbbb954cd05fbe6 309 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 81 302 6.3E-13 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_05730 0d80a94c5feefed19cbbb954cd05fbe6 309 SUPERFAMILY SSF161098 20 305 3.01E-39 T 14-10-2018 IPR035906 MetI-like superfamily MB46_03485 e4961ef939df714618c1632129147063 190 Pfam PF01551 Peptidase family M23 75 173 1.2E-12 T 14-10-2018 IPR016047 Peptidase M23 MB46_03485 e4961ef939df714618c1632129147063 190 SUPERFAMILY SSF51261 39 177 1.33E-16 T 14-10-2018 IPR011055 Duplicated hybrid motif MB46_03485 e4961ef939df714618c1632129147063 190 Gene3D G3DSA:2.70.70.10 38 178 1.9E-17 T 14-10-2018 IPR011055 Duplicated hybrid motif MB46_12295 aa3deecdd701500b1217920d925fbe5f 548 Pfam PF13556 PucR C-terminal helix-turn-helix domain 484 540 4.1E-20 T 14-10-2018 IPR025736 PucR C-terminal helix-turn-helix domain MB46_12295 aa3deecdd701500b1217920d925fbe5f 548 Gene3D G3DSA:1.10.10.2840 409 546 1.9E-19 T 14-10-2018 MB46_16615 1f946ae26e11a119c5df3899b167ec1d 424 Gene3D G3DSA:1.20.1250.20 26 213 9.5E-18 T 14-10-2018 MB46_16615 1f946ae26e11a119c5df3899b167ec1d 424 Gene3D G3DSA:1.20.1250.20 238 422 5.3E-24 T 14-10-2018 MB46_16615 1f946ae26e11a119c5df3899b167ec1d 424 SUPERFAMILY SSF103473 22 420 2.75E-47 T 14-10-2018 IPR036259 MFS transporter superfamily MB46_16615 1f946ae26e11a119c5df3899b167ec1d 424 Pfam PF07690 Major Facilitator Superfamily 60 294 2.8E-18 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MB46_07485 414d2b05b23d6f6dd3ae486367fcff66 94 SUPERFAMILY SSF54909 1 86 8.67E-22 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel MB46_07485 414d2b05b23d6f6dd3ae486367fcff66 94 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 76 5.3E-17 T 14-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain MB46_07485 414d2b05b23d6f6dd3ae486367fcff66 94 Gene3D G3DSA:3.30.70.100 1 92 1.1E-22 T 14-10-2018 MB46_12400 e9bf5c7198246a2f316d3c04e4106301 210 Pfam PF01596 O-methyltransferase 22 209 2.3E-22 T 14-10-2018 IPR002935 O-methyltransferase, family 3 GO:0008171 MB46_12400 e9bf5c7198246a2f316d3c04e4106301 210 SUPERFAMILY SSF53335 26 210 5.42E-31 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MB46_12400 e9bf5c7198246a2f316d3c04e4106301 210 Gene3D G3DSA:3.40.50.150 3 210 1.7E-55 T 14-10-2018 MB46_06415 fbb1be59def69d9c0b267d2c48aef81d 250 SUPERFAMILY SSF56214 11 112 8.89E-7 T 14-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 MB46_06415 fbb1be59def69d9c0b267d2c48aef81d 250 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 122 185 5.0E-6 T 14-10-2018 IPR008278 4'-phosphopantetheinyl transferase domain GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 MB46_06415 fbb1be59def69d9c0b267d2c48aef81d 250 SUPERFAMILY SSF56214 121 192 1.12E-8 T 14-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 MB46_06415 fbb1be59def69d9c0b267d2c48aef81d 250 Gene3D G3DSA:3.90.470.20 16 135 1.8E-13 T 14-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 MB46_06145 f1c32d8973e17ada7e8adefa0b28519f 301 Gene3D G3DSA:3.30.450.180 109 288 1.1E-15 T 14-10-2018 MB46_06145 f1c32d8973e17ada7e8adefa0b28519f 301 Pfam PF13560 Helix-turn-helix domain 32 86 2.4E-16 T 14-10-2018 MB46_06145 f1c32d8973e17ada7e8adefa0b28519f 301 Gene3D G3DSA:1.10.260.40 23 99 3.4E-8 T 14-10-2018 MB46_06145 f1c32d8973e17ada7e8adefa0b28519f 301 SMART SM00530 6 83 5.5E-5 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MB46_06145 f1c32d8973e17ada7e8adefa0b28519f 301 SUPERFAMILY SSF47413 32 80 3.26E-8 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MB46_18180 3845faf4a8382021c276146589a32dc3 581 Pfam PF00664 ABC transporter transmembrane region 35 300 2.0E-37 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 MB46_18180 3845faf4a8382021c276146589a32dc3 581 SUPERFAMILY SSF52540 339 577 1.36E-65 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_18180 3845faf4a8382021c276146589a32dc3 581 Pfam PF00005 ABC transporter 358 507 9.9E-26 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_18180 3845faf4a8382021c276146589a32dc3 581 Gene3D G3DSA:1.20.1560.10 4 331 8.0E-63 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MB46_18180 3845faf4a8382021c276146589a32dc3 581 SMART SM00382 367 553 1.4E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_18180 3845faf4a8382021c276146589a32dc3 581 SUPERFAMILY SSF90123 19 327 3.53E-61 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MB46_18180 3845faf4a8382021c276146589a32dc3 581 Gene3D G3DSA:3.40.50.300 338 581 9.6E-70 T 14-10-2018 MB46_13160 b10ebbdec87f5fb7ccc7459b2086b95d 408 Pfam PF00534 Glycosyl transferases group 1 204 374 2.6E-36 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 MB46_13160 b10ebbdec87f5fb7ccc7459b2086b95d 408 TIGRFAM TIGR03449 mycothiol_MshA: D-inositol-3-phosphate glycosyltransferase 1 398 6.4E-141 T 14-10-2018 IPR017814 Mycothiol biosynthesis protein, MshA GO:0008375|GO:0010125 MB46_13160 b10ebbdec87f5fb7ccc7459b2086b95d 408 SUPERFAMILY SSF53756 16 391 6.0E-79 T 14-10-2018 MB46_13160 b10ebbdec87f5fb7ccc7459b2086b95d 408 Gene3D G3DSA:3.40.50.2000 1 392 4.3E-119 T 14-10-2018 MB46_13160 b10ebbdec87f5fb7ccc7459b2086b95d 408 Gene3D G3DSA:3.40.50.2000 194 378 4.3E-119 T 14-10-2018 MB46_13160 b10ebbdec87f5fb7ccc7459b2086b95d 408 Pfam PF13439 Glycosyltransferase Family 4 17 197 4.1E-29 T 14-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 MB46_10130 3057742052708866c7b7b3f456f7b014 393 Gene3D G3DSA:3.90.1150.10 18 377 2.9E-48 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MB46_10130 3057742052708866c7b7b3f456f7b014 393 Gene3D G3DSA:3.40.640.10 31 280 2.9E-48 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MB46_10130 3057742052708866c7b7b3f456f7b014 393 Pfam PF00266 Aminotransferase class-V 58 299 7.1E-21 T 14-10-2018 IPR000192 Aminotransferase class V domain MB46_10130 3057742052708866c7b7b3f456f7b014 393 SUPERFAMILY SSF53383 9 380 2.28E-51 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MB46_17710 7ecedf8d190815387d7ef608291f90d0 314 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 91 302 8.0E-13 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_17710 7ecedf8d190815387d7ef608291f90d0 314 SUPERFAMILY SSF161098 73 300 7.19E-57 T 14-10-2018 IPR035906 MetI-like superfamily MB46_17710 7ecedf8d190815387d7ef608291f90d0 314 SUPERFAMILY SSF160964 30 83 1.7E-6 T 14-10-2018 MB46_17710 7ecedf8d190815387d7ef608291f90d0 314 Gene3D G3DSA:1.10.3720.10 69 309 1.1E-67 T 14-10-2018 IPR035906 MetI-like superfamily MB46_08195 c44e3a0e92f3d7f19d18c3c6da320685 188 TIGRFAM TIGR00077 lspA: signal peptidase II 23 166 2.6E-29 T 14-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 MB46_08195 c44e3a0e92f3d7f19d18c3c6da320685 188 Pfam PF01252 Signal peptidase (SPase) II 29 164 4.8E-32 T 14-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 MB46_08195 c44e3a0e92f3d7f19d18c3c6da320685 188 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 19 171 14.802 T 14-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 MB46_08195 c44e3a0e92f3d7f19d18c3c6da320685 188 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 146 162 2.6E-14 T 14-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 MB46_08195 c44e3a0e92f3d7f19d18c3c6da320685 188 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 66 74 2.6E-14 T 14-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 MB46_08195 c44e3a0e92f3d7f19d18c3c6da320685 188 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 108 123 2.6E-14 T 14-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 MB46_08195 c44e3a0e92f3d7f19d18c3c6da320685 188 ProSitePatterns PS00855 Signal peptidases II signature. 111 123 - T 14-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 MB46_00460 09b1b0be8b2631e669304f5dfbe0e3e9 385 Gene3D G3DSA:1.20.1250.20 1 373 2.5E-31 T 14-10-2018 MB46_00460 09b1b0be8b2631e669304f5dfbe0e3e9 385 SUPERFAMILY SSF103473 4 374 1.29E-34 T 14-10-2018 IPR036259 MFS transporter superfamily MB46_00460 09b1b0be8b2631e669304f5dfbe0e3e9 385 Pfam PF07690 Major Facilitator Superfamily 3 211 7.0E-16 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MB46_03965 f0f4c5bb9a3644e23b60989035ca42e6 365 Pfam PF00155 Aminotransferase class I and II 31 355 8.2E-55 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MB46_03965 f0f4c5bb9a3644e23b60989035ca42e6 365 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 11 363 52.108 T 14-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 MB46_03965 f0f4c5bb9a3644e23b60989035ca42e6 365 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 226 235 - T 14-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 MB46_03965 f0f4c5bb9a3644e23b60989035ca42e6 365 SUPERFAMILY SSF53383 31 362 4.17E-71 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MB46_03965 f0f4c5bb9a3644e23b60989035ca42e6 365 Gene3D G3DSA:3.90.1150.10 16 356 6.5E-115 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MB46_03965 f0f4c5bb9a3644e23b60989035ca42e6 365 Gene3D G3DSA:3.40.640.10 53 276 6.5E-115 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MB46_03965 f0f4c5bb9a3644e23b60989035ca42e6 365 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 13 361 6.8E-91 T 14-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 MB46_16380 e50ba8009ea29beb049d03f7a300a67e 190 Gene3D G3DSA:1.10.3300.10 2 188 3.6E-50 T 14-10-2018 IPR023286 ABATE domain superfamily MB46_16380 e50ba8009ea29beb049d03f7a300a67e 190 SUPERFAMILY SSF160904 2 185 1.27E-46 T 14-10-2018 MB46_16380 e50ba8009ea29beb049d03f7a300a67e 190 Pfam PF07336 Putative stress-induced transcription regulator 14 138 7.0E-15 T 14-10-2018 IPR010852 Putative stress-induced transcription regulator MB46_16380 e50ba8009ea29beb049d03f7a300a67e 190 Pfam PF11706 CGNR zinc finger 143 186 4.8E-18 T 14-10-2018 IPR021005 Zinc finger, CGNR MB46_18560 587dfe33f72cb4a026132a39490caabf 370 SUPERFAMILY SSF56349 71 354 6.08E-49 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MB46_18560 587dfe33f72cb4a026132a39490caabf 370 Pfam PF00589 Phage integrase family 175 349 2.3E-20 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MB46_18560 587dfe33f72cb4a026132a39490caabf 370 Gene3D G3DSA:1.10.443.10 172 362 1.3E-36 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 MB46_18560 587dfe33f72cb4a026132a39490caabf 370 Gene3D G3DSA:1.10.150.130 59 171 6.7E-18 T 14-10-2018 IPR010998 Integrase/recombinase, N-terminal MB46_09495 846636a96a00c705dbfb479281ac0821 167 Pfam PF11343 Protein of unknown function (DUF3145) 9 164 2.7E-69 T 14-10-2018 IPR021491 Protein of unknown function DUF3145 MB46_17560 15fa52bbb47f3e1bb8272c5d2314904b 224 SUPERFAMILY SSF52266 1 210 3.33E-46 T 14-10-2018 MB46_17560 15fa52bbb47f3e1bb8272c5d2314904b 224 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 6 195 2.5E-19 T 14-10-2018 IPR013830 SGNH hydrolase-type esterase domain MB46_17560 15fa52bbb47f3e1bb8272c5d2314904b 224 Gene3D G3DSA:3.40.50.1110 1 222 4.6E-57 T 14-10-2018 IPR036514 SGNH hydrolase superfamily MB46_11775 7e243a66617dd30431209ef4fbf94600 267 SUPERFAMILY SSF53335 20 209 1.03E-33 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MB46_11775 7e243a66617dd30431209ef4fbf94600 267 Pfam PF13649 Methyltransferase domain 44 139 3.5E-16 T 14-10-2018 MB46_11775 7e243a66617dd30431209ef4fbf94600 267 Gene3D G3DSA:3.40.50.150 9 251 8.7E-32 T 14-10-2018 MB46_16770 74df33423cf5f0173a34222a45ceb4df 431 SUPERFAMILY SSF103473 1 410 2.62E-58 T 14-10-2018 IPR036259 MFS transporter superfamily MB46_16770 74df33423cf5f0173a34222a45ceb4df 431 Gene3D G3DSA:1.20.1250.20 1 180 1.0E-29 T 14-10-2018 MB46_16770 74df33423cf5f0173a34222a45ceb4df 431 Gene3D G3DSA:1.20.1250.20 206 412 6.8E-19 T 14-10-2018 MB46_16770 74df33423cf5f0173a34222a45ceb4df 431 Pfam PF07690 Major Facilitator Superfamily 3 334 4.2E-34 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MB46_15700 9fe3c317d890dd4ff1e1d18e3977177a 293 PRINTS PR01438 Universal stress protein signature 116 138 1.6E-5 T 14-10-2018 IPR006015 Universal stress protein A MB46_15700 9fe3c317d890dd4ff1e1d18e3977177a 293 PRINTS PR01438 Universal stress protein signature 98 110 1.6E-5 T 14-10-2018 IPR006015 Universal stress protein A MB46_15700 9fe3c317d890dd4ff1e1d18e3977177a 293 SUPERFAMILY SSF52402 2 141 2.93E-22 T 14-10-2018 MB46_15700 9fe3c317d890dd4ff1e1d18e3977177a 293 Gene3D G3DSA:3.40.50.620 1 139 1.7E-20 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MB46_15700 9fe3c317d890dd4ff1e1d18e3977177a 293 Gene3D G3DSA:3.40.50.620 140 280 6.3E-12 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MB46_15700 9fe3c317d890dd4ff1e1d18e3977177a 293 Pfam PF00582 Universal stress protein family 4 137 2.8E-15 T 14-10-2018 IPR006016 UspA MB46_15700 9fe3c317d890dd4ff1e1d18e3977177a 293 Pfam PF00582 Universal stress protein family 157 281 1.9E-8 T 14-10-2018 IPR006016 UspA MB46_15700 9fe3c317d890dd4ff1e1d18e3977177a 293 SUPERFAMILY SSF52402 151 285 8.04E-12 T 14-10-2018 MB46_06240 93c76e9053f5420cbfc33477f9d4d84e 118 SUPERFAMILY SSF158560 4 113 1.16E-28 T 14-10-2018 MB46_06240 93c76e9053f5420cbfc33477f9d4d84e 118 Pfam PF06304 Protein of unknown function (DUF1048) 12 113 3.2E-26 T 14-10-2018 IPR008316 Uncharacterised conserved protein UCP029876 MB46_06240 93c76e9053f5420cbfc33477f9d4d84e 118 Gene3D G3DSA:1.10.1900.10 2 115 1.2E-37 T 14-10-2018 MB46_05380 fa3cc1f09a4d1cc62a478b56359bc16d 220 Gene3D G3DSA:3.40.50.1000 2 182 3.0E-44 T 14-10-2018 IPR023214 HAD superfamily MB46_05380 fa3cc1f09a4d1cc62a478b56359bc16d 220 Pfam PF13419 Haloacid dehalogenase-like hydrolase 1 179 3.9E-20 T 14-10-2018 MB46_05380 fa3cc1f09a4d1cc62a478b56359bc16d 220 SUPERFAMILY SSF56784 1 182 8.85E-38 T 14-10-2018 IPR036412 HAD-like superfamily MB46_05380 fa3cc1f09a4d1cc62a478b56359bc16d 220 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 67 178 4.1E-9 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MB46_05380 fa3cc1f09a4d1cc62a478b56359bc16d 220 Gene3D G3DSA:1.10.150.240 7 75 3.0E-44 T 14-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 MB46_04630 e73695ce4edbf884dbc81edea294e068 357 Gene3D G3DSA:3.40.50.300 133 339 1.4E-76 T 14-10-2018 MB46_04630 e73695ce4edbf884dbc81edea294e068 357 Pfam PF02562 PhoH-like protein 136 338 2.5E-94 T 14-10-2018 IPR003714 PhoH-like protein GO:0005524 MB46_04630 e73695ce4edbf884dbc81edea294e068 357 SUPERFAMILY SSF52540 122 303 4.75E-41 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_14580 19185f18fa6a1466678c47c424d39edf 144 SUPERFAMILY SSF54593 6 143 1.88E-9 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MB46_14690 58da01646bc73a22f79835a4dde92405 276 Gene3D G3DSA:3.30.450.180 108 276 2.1E-15 T 14-10-2018 MB46_14690 58da01646bc73a22f79835a4dde92405 276 Pfam PF13560 Helix-turn-helix domain 8 83 1.8E-13 T 14-10-2018 MB46_16400 c4653af3ddc5488659a7fcb91a3b20b0 104 Pfam PF02583 Metal-sensitive transcriptional repressor 13 99 1.6E-31 T 14-10-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 MB46_16400 c4653af3ddc5488659a7fcb91a3b20b0 104 Gene3D G3DSA:1.20.58.1000 10 104 5.0E-32 T 14-10-2018 IPR038390 Metal-sensitive transcriptional repressor superfamily MB46_09255 b987d04519e36963ae8c4650a0b8feae 405 Gene3D G3DSA:3.90.1150.10 49 373 1.7E-109 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MB46_09255 b987d04519e36963ae8c4650a0b8feae 405 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 241 250 - T 14-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 MB46_09255 b987d04519e36963ae8c4650a0b8feae 405 Gene3D G3DSA:3.40.640.10 63 292 1.7E-109 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MB46_09255 b987d04519e36963ae8c4650a0b8feae 405 Pfam PF00155 Aminotransferase class I and II 47 379 6.5E-54 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MB46_09255 b987d04519e36963ae8c4650a0b8feae 405 SUPERFAMILY SSF53383 42 387 6.8E-84 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MB46_18400 c141dc1ad036c6f60346c42cb8ce35d3 360 Pfam PF03663 Glycosyl hydrolase family 76 74 312 1.3E-15 T 14-10-2018 IPR005198 Glycoside hydrolase, family 76 MB46_18400 c141dc1ad036c6f60346c42cb8ce35d3 360 Gene3D G3DSA:1.50.10.20 49 360 1.1E-61 T 14-10-2018 MB46_18400 c141dc1ad036c6f60346c42cb8ce35d3 360 SUPERFAMILY SSF48208 64 323 1.64E-19 T 14-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 MB46_17460 cd0d584bbd2a8cad4039ec6b2c6c9874 275 Gene3D G3DSA:3.20.20.150 6 272 1.8E-42 T 14-10-2018 MB46_17460 cd0d584bbd2a8cad4039ec6b2c6c9874 275 Pfam PF01261 Xylose isomerase-like TIM barrel 34 221 7.0E-20 T 14-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain MB46_17460 cd0d584bbd2a8cad4039ec6b2c6c9874 275 SUPERFAMILY SSF51658 16 266 1.44E-41 T 14-10-2018 IPR036237 Xylose isomerase-like superfamily MB46_08720 e789bc94321de2dc472f0283c5ce859a 187 Gene3D G3DSA:3.30.428.10 16 187 1.0E-53 T 14-10-2018 IPR036265 HIT-like superfamily MB46_08720 e789bc94321de2dc472f0283c5ce859a 187 SUPERFAMILY SSF54197 25 175 1.28E-40 T 14-10-2018 IPR036265 HIT-like superfamily MB46_08720 e789bc94321de2dc472f0283c5ce859a 187 Pfam PF01230 HIT domain 59 151 1.7E-14 T 14-10-2018 IPR001310 Histidine triad (HIT) protein MB46_07545 cf17e5fcef95c9984c2433897c60b5f4 542 Pfam PF03806 AbgT putative transporter family 7 540 3.0E-139 T 14-10-2018 IPR004697 p-Aminobenzoyl-glutamate transport protein AbgT GO:0015558|GO:1902604 MB46_06665 4959a5f8ba6d2f39c03dd4a0efc77d90 79 Gene3D G3DSA:3.40.50.720 5 78 1.6E-10 T 14-10-2018 MB46_06665 4959a5f8ba6d2f39c03dd4a0efc77d90 79 SUPERFAMILY SSF51735 10 66 3.92E-9 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_16685 78a723494f5a874d12e1a55d288fbde0 486 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 434 449 2.1E-44 T 14-10-2018 MB46_16685 78a723494f5a874d12e1a55d288fbde0 486 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 456 476 2.1E-44 T 14-10-2018 MB46_16685 78a723494f5a874d12e1a55d288fbde0 486 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 279 293 2.1E-44 T 14-10-2018 MB46_16685 78a723494f5a874d12e1a55d288fbde0 486 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 368 389 2.1E-44 T 14-10-2018 MB46_16685 78a723494f5a874d12e1a55d288fbde0 486 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 40 55 2.1E-44 T 14-10-2018 MB46_16685 78a723494f5a874d12e1a55d288fbde0 486 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 8 30 2.1E-44 T 14-10-2018 MB46_16685 78a723494f5a874d12e1a55d288fbde0 486 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 143 152 2.1E-44 T 14-10-2018 MB46_16685 78a723494f5a874d12e1a55d288fbde0 486 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 179 204 2.1E-44 T 14-10-2018 MB46_16685 78a723494f5a874d12e1a55d288fbde0 486 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 321 328 2.1E-44 T 14-10-2018 MB46_16685 78a723494f5a874d12e1a55d288fbde0 486 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 336 2.6E-40 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MB46_16685 78a723494f5a874d12e1a55d288fbde0 486 SUPERFAMILY SSF51905 4 351 7.2E-40 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_16685 78a723494f5a874d12e1a55d288fbde0 486 SUPERFAMILY SSF55424 370 484 1.19E-28 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 MB46_16685 78a723494f5a874d12e1a55d288fbde0 486 Gene3D G3DSA:3.50.50.60 159 292 1.2E-78 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_16685 78a723494f5a874d12e1a55d288fbde0 486 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 179 197 4.4E-11 T 14-10-2018 MB46_16685 78a723494f5a874d12e1a55d288fbde0 486 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 4.4E-11 T 14-10-2018 MB46_16685 78a723494f5a874d12e1a55d288fbde0 486 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 278 294 4.4E-11 T 14-10-2018 MB46_16685 78a723494f5a874d12e1a55d288fbde0 486 Gene3D G3DSA:3.50.50.60 8 348 1.2E-78 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_16685 78a723494f5a874d12e1a55d288fbde0 486 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 372 481 3.5E-26 T 14-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 MB46_16685 78a723494f5a874d12e1a55d288fbde0 486 PIRSF PIRSF000350 1 485 8.7E-74 T 14-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 MB46_16685 78a723494f5a874d12e1a55d288fbde0 486 Gene3D G3DSA:3.30.390.30 371 486 5.9E-30 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 MB46_14235 b2742bc309be7362e4429adcf6e6a95d 143 Gene3D G3DSA:3.10.180.10 1 142 4.0E-52 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MB46_14235 b2742bc309be7362e4429adcf6e6a95d 143 SUPERFAMILY SSF54593 1 131 6.74E-22 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MB46_14235 b2742bc309be7362e4429adcf6e6a95d 143 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 124 1.9E-4 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MB46_03000 6f80f9e42fcf4b6cc5ac1c877a35db62 418 Pfam PF01547 Bacterial extracellular solute-binding protein 42 334 5.7E-27 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein MB46_03000 6f80f9e42fcf4b6cc5ac1c877a35db62 418 Gene3D G3DSA:3.40.190.10 45 360 1.1E-76 T 14-10-2018 MB46_03000 6f80f9e42fcf4b6cc5ac1c877a35db62 418 Gene3D G3DSA:3.40.190.10 142 379 1.1E-76 T 14-10-2018 MB46_03000 6f80f9e42fcf4b6cc5ac1c877a35db62 418 SUPERFAMILY SSF53850 21 408 1.48E-44 T 14-10-2018 MB46_13330 54338a0b6d9a1ccc3f6afbfdef4d02ce 277 PRINTS PR00599 Methionine aminopeptidase-1 signature 202 214 5.9E-19 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 MB46_13330 54338a0b6d9a1ccc3f6afbfdef4d02ce 277 PRINTS PR00599 Methionine aminopeptidase-1 signature 73 86 5.9E-19 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 MB46_13330 54338a0b6d9a1ccc3f6afbfdef4d02ce 277 PRINTS PR00599 Methionine aminopeptidase-1 signature 95 111 5.9E-19 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 MB46_13330 54338a0b6d9a1ccc3f6afbfdef4d02ce 277 PRINTS PR00599 Methionine aminopeptidase-1 signature 171 183 5.9E-19 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 MB46_13330 54338a0b6d9a1ccc3f6afbfdef4d02ce 277 SUPERFAMILY SSF55920 8 260 8.37E-66 T 14-10-2018 IPR036005 Creatinase/aminopeptidase-like MB46_13330 54338a0b6d9a1ccc3f6afbfdef4d02ce 277 Gene3D G3DSA:3.90.230.10 2 266 4.2E-84 T 14-10-2018 MB46_13330 54338a0b6d9a1ccc3f6afbfdef4d02ce 277 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 11 259 4.0E-73 T 14-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 MB46_13330 54338a0b6d9a1ccc3f6afbfdef4d02ce 277 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 177 195 - T 14-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 MB46_13330 54338a0b6d9a1ccc3f6afbfdef4d02ce 277 Hamap MF_01974 Methionine aminopeptidase [map]. 8 260 33.997 T 14-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 MB46_13330 54338a0b6d9a1ccc3f6afbfdef4d02ce 277 Pfam PF00557 Metallopeptidase family M24 18 248 2.9E-42 T 14-10-2018 IPR000994 Peptidase M24 MB46_18840 90cb506add1a0a5c0eed8100a746b042 299 Gene3D G3DSA:3.90.850.10 74 292 1.4E-74 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 MB46_18840 90cb506add1a0a5c0eed8100a746b042 299 SUPERFAMILY SSF56529 68 283 1.44E-69 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 MB46_18840 90cb506add1a0a5c0eed8100a746b042 299 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 79 283 1.1E-64 T 14-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 MB46_08325 2950a7770f649554529bd4ce19077ba8 465 SUPERFAMILY SSF51569 24 462 4.15E-192 T 14-10-2018 MB46_08325 2950a7770f649554529bd4ce19077ba8 465 TIGRFAM TIGR01358 DAHP_synth_II: 3-deoxy-7-phosphoheptulonate synthase 28 463 1.8E-205 T 14-10-2018 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 MB46_08325 2950a7770f649554529bd4ce19077ba8 465 Pfam PF01474 Class-II DAHP synthetase family 28 458 8.3E-196 T 14-10-2018 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 MB46_08325 2950a7770f649554529bd4ce19077ba8 465 Gene3D G3DSA:3.20.20.70 207 463 1.0E-103 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MB46_03175 d7cd24bab39acfcf8f49c808bd8397ff 466 SUPERFAMILY SSF53383 5 457 2.32E-108 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MB46_03175 d7cd24bab39acfcf8f49c808bd8397ff 466 Gene3D G3DSA:3.90.1150.170 39 443 3.0E-90 T 14-10-2018 MB46_03175 d7cd24bab39acfcf8f49c808bd8397ff 466 Gene3D G3DSA:3.40.640.10 102 344 3.0E-90 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MB46_03175 d7cd24bab39acfcf8f49c808bd8397ff 466 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 45 398 1.7E-40 T 14-10-2018 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 MB46_06225 8f9d066a576ba3762a0ec2a9cf378eea 696 Gene3D G3DSA:3.40.50.880 403 625 1.8E-47 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like MB46_06225 8f9d066a576ba3762a0ec2a9cf378eea 696 Pfam PF08532 Beta-galactosidase trimerisation domain 405 617 4.2E-25 T 14-10-2018 IPR013738 Beta-galactosidase trimerisation GO:0004565|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 MB46_06225 8f9d066a576ba3762a0ec2a9cf378eea 696 Gene3D G3DSA:3.20.20.80 1 399 7.7E-110 T 14-10-2018 MB46_06225 8f9d066a576ba3762a0ec2a9cf378eea 696 Pfam PF02449 Beta-galactosidase 14 391 3.6E-79 T 14-10-2018 IPR013529 Glycoside hydrolase, family 42, N-terminal GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 MB46_06225 8f9d066a576ba3762a0ec2a9cf378eea 696 SUPERFAMILY SSF51445 9 395 7.81E-70 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily MB46_06225 8f9d066a576ba3762a0ec2a9cf378eea 696 SUPERFAMILY SSF52317 403 619 2.29E-24 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like MB46_04300 c75dbf457b96264522200fe70046e1b8 339 Pfam PF00294 pfkB family carbohydrate kinase 1 303 1.1E-44 T 14-10-2018 IPR011611 Carbohydrate kinase PfkB MB46_04300 c75dbf457b96264522200fe70046e1b8 339 SUPERFAMILY SSF53613 1 309 4.21E-63 T 14-10-2018 IPR029056 Ribokinase-like MB46_04300 c75dbf457b96264522200fe70046e1b8 339 Gene3D G3DSA:3.40.1190.20 1 315 3.1E-76 T 14-10-2018 IPR029056 Ribokinase-like MB46_09260 d13af681d916e764450096cbc551569a 456 Pfam PF00202 Aminotransferase class-III 64 442 6.9E-107 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MB46_09260 d13af681d916e764450096cbc551569a 456 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 271 308 - T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MB46_09260 d13af681d916e764450096cbc551569a 456 Gene3D G3DSA:3.90.1150.10 26 442 4.8E-146 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MB46_09260 d13af681d916e764450096cbc551569a 456 Gene3D G3DSA:3.40.640.10 81 359 4.8E-146 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MB46_09260 d13af681d916e764450096cbc551569a 456 TIGRFAM TIGR00508 bioA: adenosylmethionine-8-amino-7-oxononanoate transaminase 30 449 1.4E-152 T 14-10-2018 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 MB46_09260 d13af681d916e764450096cbc551569a 456 SUPERFAMILY SSF53383 40 447 2.24E-100 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MB46_04760 21225f9fd5f8d612a1ea686d3ef2de33 93 Gene3D G3DSA:3.30.70.920 3 78 3.3E-19 T 14-10-2018 MB46_04760 21225f9fd5f8d612a1ea686d3ef2de33 93 SUPERFAMILY SSF54909 2 78 4.29E-17 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel MB46_04760 21225f9fd5f8d612a1ea686d3ef2de33 93 Pfam PF01037 Lrp/AsnC ligand binding domain 6 76 4.0E-14 T 14-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain MB46_11425 b5f9e67740346f79397f3e672411f0dd 252 SUPERFAMILY SSF53448 8 229 1.85E-29 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MB46_11425 b5f9e67740346f79397f3e672411f0dd 252 Gene3D G3DSA:3.90.550.10 2 248 2.2E-36 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MB46_11425 b5f9e67740346f79397f3e672411f0dd 252 Pfam PF00535 Glycosyl transferase family 2 11 137 2.7E-21 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MB46_10500 0fe9dbd59e23eaeef566f60aba2a89b9 490 SUPERFAMILY SSF103473 24 486 7.59E-37 T 14-10-2018 IPR036259 MFS transporter superfamily MB46_10500 0fe9dbd59e23eaeef566f60aba2a89b9 490 Gene3D G3DSA:1.20.1720.10 22 240 4.4E-18 T 14-10-2018 MB46_10500 0fe9dbd59e23eaeef566f60aba2a89b9 490 Pfam PF07690 Major Facilitator Superfamily 28 263 1.6E-10 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MB46_10500 0fe9dbd59e23eaeef566f60aba2a89b9 490 Gene3D G3DSA:1.20.1250.20 277 483 9.0E-14 T 14-10-2018 MB46_15890 ef26a175a6afd63191597e06b836c4e6 237 SUPERFAMILY SSF52172 15 201 2.41E-36 T 14-10-2018 IPR011006 CheY-like superfamily MB46_15890 ef26a175a6afd63191597e06b836c4e6 237 Gene3D G3DSA:3.40.50.12740 16 230 1.0E-73 T 14-10-2018 MB46_15890 ef26a175a6afd63191597e06b836c4e6 237 SMART SM00448 16 129 2.4E-35 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MB46_15890 ef26a175a6afd63191597e06b836c4e6 237 ProSitePatterns PS00622 LuxR-type HTH domain signature. 184 211 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_15890 ef26a175a6afd63191597e06b836c4e6 237 Pfam PF00196 Bacterial regulatory proteins, luxR family 170 224 5.1E-20 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_15890 ef26a175a6afd63191597e06b836c4e6 237 Pfam PF00072 Response regulator receiver domain 18 130 4.7E-30 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MB46_15890 ef26a175a6afd63191597e06b836c4e6 237 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 200 212 7.0E-14 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_15890 ef26a175a6afd63191597e06b836c4e6 237 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 184 200 7.0E-14 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_15890 ef26a175a6afd63191597e06b836c4e6 237 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 170 184 7.0E-14 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_15890 ef26a175a6afd63191597e06b836c4e6 237 SMART SM00421 167 224 3.8E-25 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MB46_14510 3cd090812fdb685788b32a2b86480730 332 Gene3D G3DSA:3.40.50.720 1 261 2.4E-22 T 14-10-2018 MB46_14510 3cd090812fdb685788b32a2b86480730 332 SUPERFAMILY SSF51735 3 255 3.34E-22 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_14510 3cd090812fdb685788b32a2b86480730 332 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 201 2.4E-5 T 14-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 MB46_16435 840334647654a1ff8ba9f056ac798050 380 Pfam PF08125 Mannitol dehydrogenase C-terminal domain 150 363 8.3E-49 T 14-10-2018 IPR013118 Mannitol dehydrogenase, C-terminal GO:0016491|GO:0050662|GO:0055114 MB46_16435 840334647654a1ff8ba9f056ac798050 380 Hamap MF_00196 Mannitol-1-phosphate 5-dehydrogenase [mtlD]. 1 375 35.758 T 14-10-2018 IPR023028 Mannitol-1-phosphate 5-dehydrogenase GO:0008926|GO:0019594|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 MB46_16435 840334647654a1ff8ba9f056ac798050 380 SUPERFAMILY SSF51735 1 200 5.42E-40 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_16435 840334647654a1ff8ba9f056ac798050 380 PRINTS PR00084 Mannitol dehydrogenase signature 149 162 2.9E-14 T 14-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 MB46_16435 840334647654a1ff8ba9f056ac798050 380 PRINTS PR00084 Mannitol dehydrogenase signature 3 13 2.9E-14 T 14-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 MB46_16435 840334647654a1ff8ba9f056ac798050 380 PRINTS PR00084 Mannitol dehydrogenase signature 167 182 2.9E-14 T 14-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 MB46_16435 840334647654a1ff8ba9f056ac798050 380 PRINTS PR00084 Mannitol dehydrogenase signature 114 127 2.9E-14 T 14-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 MB46_16435 840334647654a1ff8ba9f056ac798050 380 Pfam PF01232 Mannitol dehydrogenase Rossmann domain 1 122 7.9E-22 T 14-10-2018 IPR013131 Mannitol dehydrogenase, N-terminal GO:0016491|GO:0055114 MB46_16435 840334647654a1ff8ba9f056ac798050 380 Gene3D G3DSA:3.40.50.720 1 202 2.5E-68 T 14-10-2018 MB46_16435 840334647654a1ff8ba9f056ac798050 380 Gene3D G3DSA:1.10.1040.10 204 377 6.5E-57 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MB46_16435 840334647654a1ff8ba9f056ac798050 380 SUPERFAMILY SSF48179 201 373 6.8E-42 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MB46_13425 966009b7c8e211f1c42059e419e35539 101 SUPERFAMILY SSF54189 7 92 4.68E-29 T 14-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 MB46_13425 966009b7c8e211f1c42059e419e35539 101 Pfam PF00276 Ribosomal protein L23 11 91 1.4E-28 T 14-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 MB46_13425 966009b7c8e211f1c42059e419e35539 101 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 10 98 20.628 T 14-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 MB46_13425 966009b7c8e211f1c42059e419e35539 101 Gene3D G3DSA:3.30.70.330 6 98 7.5E-29 T 14-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily MB46_15920 c822f1b9cab24ee3a9a09220b26be393 229 Gene3D G3DSA:3.40.50.1000 2 199 6.3E-38 T 14-10-2018 IPR023214 HAD superfamily MB46_15920 c822f1b9cab24ee3a9a09220b26be393 229 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 190 3.4E-15 T 14-10-2018 MB46_15920 c822f1b9cab24ee3a9a09220b26be393 229 Gene3D G3DSA:1.10.150.240 19 86 6.3E-38 T 14-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 MB46_15920 c822f1b9cab24ee3a9a09220b26be393 229 TIGRFAM TIGR03351 PhnX-like: phosphonatase-like hydrolase 2 223 1.4E-78 T 14-10-2018 IPR022468 Phosphonatase-like hydrolase MB46_15920 c822f1b9cab24ee3a9a09220b26be393 229 SUPERFAMILY SSF56784 1 222 1.54E-41 T 14-10-2018 IPR036412 HAD-like superfamily MB46_18725 ec74612894283cca181eeadd9ad4cbe8 257 SUPERFAMILY SSF53955 180 250 5.63E-8 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily MB46_04985 7baf9344bb812c66ea481d376ec6fbed 172 Gene3D G3DSA:3.40.630.30 3 166 1.3E-48 T 14-10-2018 MB46_04985 7baf9344bb812c66ea481d376ec6fbed 172 Pfam PF00583 Acetyltransferase (GNAT) family 58 138 4.5E-17 T 14-10-2018 IPR000182 GNAT domain MB46_04985 7baf9344bb812c66ea481d376ec6fbed 172 SUPERFAMILY SSF55729 4 153 8.58E-34 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase MB46_17790 7b217f946c82ef180db250bea0b04664 357 Pfam PF01578 Cytochrome C assembly protein 138 350 5.4E-43 T 14-10-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 MB46_17790 7b217f946c82ef180db250bea0b04664 357 TIGRFAM TIGR03144 cytochr_II_ccsB: cytochrome c-type biogenesis protein CcsB 115 353 6.6E-72 T 14-10-2018 IPR017562 Cytochrome c-type biogenesis protein CcsA GO:0017004 MB46_00820 fa7cc2bcfc22f78ef6099852e85abe9a 302 Gene3D G3DSA:3.40.190.290 96 292 2.5E-27 T 14-10-2018 MB46_00820 fa7cc2bcfc22f78ef6099852e85abe9a 302 Gene3D G3DSA:1.10.10.10 10 88 1.8E-12 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_00820 fa7cc2bcfc22f78ef6099852e85abe9a 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 11 68 3.0E-11 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MB46_00820 fa7cc2bcfc22f78ef6099852e85abe9a 302 Pfam PF03466 LysR substrate binding domain 96 291 9.9E-26 T 14-10-2018 IPR005119 LysR, substrate-binding MB46_00820 fa7cc2bcfc22f78ef6099852e85abe9a 302 SUPERFAMILY SSF46785 5 116 1.68E-13 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_00820 fa7cc2bcfc22f78ef6099852e85abe9a 302 SUPERFAMILY SSF53850 95 295 4.71E-31 T 14-10-2018 MB46_02030 d3277221e54d24de6868a89210476b37 166 Pfam PF00583 Acetyltransferase (GNAT) family 18 122 3.8E-11 T 14-10-2018 IPR000182 GNAT domain MB46_02030 d3277221e54d24de6868a89210476b37 166 Gene3D G3DSA:3.40.630.30 1 166 1.4E-43 T 14-10-2018 MB46_02030 d3277221e54d24de6868a89210476b37 166 SUPERFAMILY SSF55729 1 133 4.56E-26 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase MB46_17200 b3c458e8bddc3fed5daba85d91c435e2 219 Gene3D G3DSA:2.160.20.100 22 218 8.3E-20 T 14-10-2018 MB46_17200 b3c458e8bddc3fed5daba85d91c435e2 219 SUPERFAMILY SSF141571 31 188 3.79E-21 T 14-10-2018 MB46_17200 b3c458e8bddc3fed5daba85d91c435e2 219 Pfam PF00805 Pentapeptide repeats (8 copies) 39 76 2.4E-5 T 14-10-2018 IPR001646 Pentapeptide repeat MB46_09380 0ebe30c35f29e749264f305ae1273040 316 Gene3D G3DSA:3.40.1390.30 139 269 2.4E-65 T 14-10-2018 MB46_09380 0ebe30c35f29e749264f305ae1273040 316 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 45 287 1.5E-66 T 14-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 MB46_09380 0ebe30c35f29e749264f305ae1273040 316 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 44 307 1.4E-46 T 14-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 MB46_09380 0ebe30c35f29e749264f305ae1273040 316 Gene3D G3DSA:3.40.1390.30 48 279 2.4E-65 T 14-10-2018 MB46_09380 0ebe30c35f29e749264f305ae1273040 316 SUPERFAMILY SSF102705 42 310 8.89E-79 T 14-10-2018 IPR036069 GTP cyclohydrolase 1 type 2/Nif3 superfamily MB46_14625 84bcd53adc91fd26df07ca2f93222c0c 480 Pfam PF17173 Domain of unknown function (DUF5129) 32 370 4.9E-124 T 14-10-2018 IPR033435 Domain of unknown function DUF5129 MB46_08410 850d92785c83dd39e4f23a35032dfd3b 125 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 8 118 4.9E-21 T 14-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 MB46_08410 850d92785c83dd39e4f23a35032dfd3b 125 TIGRFAM TIGR00494 crcB: protein CrcB 8 121 1.4E-29 T 14-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 MB46_08410 850d92785c83dd39e4f23a35032dfd3b 125 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 6 123 18.724 T 14-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 MB46_10525 dbc2ab52d9f7e6f9988ddf7d9727361b 148 Gene3D G3DSA:2.60.40.10 15 107 2.2E-5 T 14-10-2018 IPR013783 Immunoglobulin-like fold MB46_08420 3a0295786f85c537b413a5915957a491 216 SUPERFAMILY SSF55136 125 196 2.79E-10 T 14-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily MB46_08420 3a0295786f85c537b413a5915957a491 216 Pfam PF06445 GyrI-like small molecule binding domain 20 200 2.6E-28 T 14-10-2018 IPR029442 GyrI-like small molecule binding domain MB46_08420 3a0295786f85c537b413a5915957a491 216 PIRSF PIRSF031644 1 205 7.7E-64 T 14-10-2018 IPR008319 Uncharacterised conserved protein UCP031644 MB46_08420 3a0295786f85c537b413a5915957a491 216 Gene3D G3DSA:3.20.80.10 1 203 5.4E-76 T 14-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily MB46_17810 5ba77f5352256d5de83a552222a22e5d 221 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 5 93 3.0E-15 T 14-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal MB46_17810 5ba77f5352256d5de83a552222a22e5d 221 SUPERFAMILY SSF51735 5 198 8.75E-30 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_17810 5ba77f5352256d5de83a552222a22e5d 221 Gene3D G3DSA:3.40.50.720 1 198 4.9E-46 T 14-10-2018 MB46_02635 9c91a33096d2079b930f9d826dd4450f 179 TIGRFAM TIGR04088 cognate_SipW: SipW-cognate class signal peptide 13 44 5.8E-6 T 14-10-2018 IPR023833 Signal peptide, camelysin MB46_02635 9c91a33096d2079b930f9d826dd4450f 179 TIGRFAM TIGR04089 exp_by_SipW_III: alternate signal-mediated exported protein, RER_14450 family 1 170 4.4E-38 T 14-10-2018 IPR024006 Conserved hypothetical protein CHP04089 MB46_01410 8cf65fb46ba941286367c18c49694050 103 Gene3D G3DSA:3.30.70.100 1 103 1.3E-34 T 14-10-2018 MB46_01410 8cf65fb46ba941286367c18c49694050 103 SUPERFAMILY SSF54909 4 96 3.43E-22 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel MB46_01410 8cf65fb46ba941286367c18c49694050 103 Pfam PF08803 Putative mono-oxygenase ydhR 6 98 5.1E-31 T 14-10-2018 IPR014910 Putative monooxygenase YdhR MB46_14190 b8b8f7639d5645ad4287e657dd015418 298 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 276 1.7E-15 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_14190 b8b8f7639d5645ad4287e657dd015418 298 SUPERFAMILY SSF161098 90 275 1.16E-30 T 14-10-2018 IPR035906 MetI-like superfamily MB46_14190 b8b8f7639d5645ad4287e657dd015418 298 Gene3D G3DSA:1.10.3720.10 90 286 6.4E-28 T 14-10-2018 IPR035906 MetI-like superfamily MB46_04910 09a6e6239f3dbb9ee5895bb6c15a6182 414 Gene3D G3DSA:3.90.1150.10 22 398 3.3E-134 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MB46_04910 09a6e6239f3dbb9ee5895bb6c15a6182 414 SUPERFAMILY SSF53383 4 399 1.45E-95 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MB46_04910 09a6e6239f3dbb9ee5895bb6c15a6182 414 Gene3D G3DSA:3.40.640.10 53 294 3.3E-134 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MB46_04910 09a6e6239f3dbb9ee5895bb6c15a6182 414 Pfam PF00155 Aminotransferase class I and II 59 395 4.5E-52 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MB46_18505 43c7f21b0a77c3b1a535556b4aaed73f 180 Gene3D G3DSA:3.40.630.30 2 176 4.5E-23 T 14-10-2018 MB46_18505 43c7f21b0a77c3b1a535556b4aaed73f 180 Pfam PF13302 Acetyltransferase (GNAT) domain 5 135 6.2E-13 T 14-10-2018 IPR000182 GNAT domain MB46_18505 43c7f21b0a77c3b1a535556b4aaed73f 180 SUPERFAMILY SSF55729 1 166 3.36E-19 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase MB46_15885 ece2f1ee98dd7f4c364f6c4d8c6d3886 258 Gene3D G3DSA:1.20.1080.10 3 242 1.9E-77 T 14-10-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 MB46_15885 ece2f1ee98dd7f4c364f6c4d8c6d3886 258 ProSitePatterns PS00221 MIP family signature. 73 81 - T 14-10-2018 IPR022357 Major intrinsic protein, conserved site Reactome: R-HSA-432047 MB46_15885 ece2f1ee98dd7f4c364f6c4d8c6d3886 258 PRINTS PR00783 Major intrinsic protein family signature 149 167 2.9E-51 T 14-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 MB46_15885 ece2f1ee98dd7f4c364f6c4d8c6d3886 258 PRINTS PR00783 Major intrinsic protein family signature 55 79 2.9E-51 T 14-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 MB46_15885 ece2f1ee98dd7f4c364f6c4d8c6d3886 258 PRINTS PR00783 Major intrinsic protein family signature 218 238 2.9E-51 T 14-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 MB46_15885 ece2f1ee98dd7f4c364f6c4d8c6d3886 258 PRINTS PR00783 Major intrinsic protein family signature 7 26 2.9E-51 T 14-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 MB46_15885 ece2f1ee98dd7f4c364f6c4d8c6d3886 258 PRINTS PR00783 Major intrinsic protein family signature 92 111 2.9E-51 T 14-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 MB46_15885 ece2f1ee98dd7f4c364f6c4d8c6d3886 258 PRINTS PR00783 Major intrinsic protein family signature 179 201 2.9E-51 T 14-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 MB46_15885 ece2f1ee98dd7f4c364f6c4d8c6d3886 258 Pfam PF00230 Major intrinsic protein 5 235 3.3E-50 T 14-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 MB46_15885 ece2f1ee98dd7f4c364f6c4d8c6d3886 258 TIGRFAM TIGR00861 MIP: MIP family channel proteins 11 235 4.4E-57 T 14-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 MB46_15885 ece2f1ee98dd7f4c364f6c4d8c6d3886 258 SUPERFAMILY SSF81338 7 240 5.23E-61 T 14-10-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 MB46_13375 5a3023d4417f862388457dc39ec824f4 194 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 13 191 42.98 T 14-10-2018 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 MB46_13375 5a3023d4417f862388457dc39ec824f4 194 Gene3D G3DSA:3.30.1440.10 11 191 1.7E-77 T 14-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MB46_13375 5a3023d4417f862388457dc39ec824f4 194 Pfam PF00281 Ribosomal protein L5 36 92 2.1E-27 T 14-10-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MB46_13375 5a3023d4417f862388457dc39ec824f4 194 PIRSF PIRSF002161 9 194 3.1E-62 T 14-10-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MB46_13375 5a3023d4417f862388457dc39ec824f4 194 SUPERFAMILY SSF55282 15 190 1.86E-74 T 14-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MB46_13375 5a3023d4417f862388457dc39ec824f4 194 Pfam PF00673 ribosomal L5P family C-terminus 96 189 4.7E-39 T 14-10-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MB46_18420 7686f3093f7960bfaa5165883a606186 189 SUPERFAMILY SSF55961 26 172 7.33E-28 T 14-10-2018 MB46_18420 7686f3093f7960bfaa5165883a606186 189 Gene3D G3DSA:3.30.530.20 11 184 3.6E-30 T 14-10-2018 IPR023393 START-like domain superfamily MB46_18420 7686f3093f7960bfaa5165883a606186 189 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 43 161 7.6E-14 T 14-10-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like MB46_13630 9c2f3a5edc7961222d4fd74a17667153 301 SUPERFAMILY SSF161098 63 290 3.53E-65 T 14-10-2018 IPR035906 MetI-like superfamily MB46_13630 9c2f3a5edc7961222d4fd74a17667153 301 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 99 299 7.3E-17 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_13630 9c2f3a5edc7961222d4fd74a17667153 301 Gene3D G3DSA:1.10.3720.10 59 301 2.1E-78 T 14-10-2018 IPR035906 MetI-like superfamily MB46_12345 82c9b0d78a64f05b79530f879abc2533 563 Gene3D G3DSA:1.20.1730.10 32 460 5.4E-50 T 14-10-2018 IPR038377 Sodium/glucose symporter superfamily MB46_12345 82c9b0d78a64f05b79530f879abc2533 563 Pfam PF00474 Sodium:solute symporter family 44 426 8.5E-30 T 14-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 MB46_15800 0ea8d73032d2971484ceb44e9a9b1ced 179 Pfam PF02342 TerD domain 3 175 3.9E-47 T 14-10-2018 IPR003325 TerD domain MB46_15800 0ea8d73032d2971484ceb44e9a9b1ced 179 Gene3D G3DSA:2.60.60.30 14 174 1.7E-45 T 14-10-2018 MB46_08310 6aeb5c4c9ec8843e595ca6d934984db7 119 Gene3D G3DSA:1.10.1660.10 9 56 4.6E-7 T 14-10-2018 MB46_19760 09c2c53b0e253d3c17a81e434c2ee639 151 SUPERFAMILY SSF55729 3 121 1.66E-16 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase MB46_19760 09c2c53b0e253d3c17a81e434c2ee639 151 Gene3D G3DSA:3.40.630.30 5 137 4.5E-17 T 14-10-2018 MB46_19760 09c2c53b0e253d3c17a81e434c2ee639 151 Pfam PF00583 Acetyltransferase (GNAT) family 54 114 1.8E-9 T 14-10-2018 IPR000182 GNAT domain MB46_00150 e7589d2c76b2faaa67b4016af16dbfa3 325 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 117 323 8.3E-42 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_00150 e7589d2c76b2faaa67b4016af16dbfa3 325 Gene3D G3DSA:1.10.3720.10 90 319 1.2E-18 T 14-10-2018 IPR035906 MetI-like superfamily MB46_00150 e7589d2c76b2faaa67b4016af16dbfa3 325 SUPERFAMILY SSF161098 95 311 1.47E-15 T 14-10-2018 IPR035906 MetI-like superfamily MB46_00350 32c0fd0f573dc374ca0ee36f0b97c1ea 321 Gene3D G3DSA:1.10.3720.10 1 277 2.9E-62 T 14-10-2018 IPR035906 MetI-like superfamily MB46_00350 32c0fd0f573dc374ca0ee36f0b97c1ea 321 SUPERFAMILY SSF161098 51 273 7.59E-54 T 14-10-2018 IPR035906 MetI-like superfamily MB46_00350 32c0fd0f573dc374ca0ee36f0b97c1ea 321 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 86 275 5.8E-19 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_06245 450c7a7379cc037f729e20ddad8f52c9 116 Pfam PF03551 Transcriptional regulator PadR-like family 17 89 1.4E-19 T 14-10-2018 IPR005149 Transcription regulator PadR, N-terminal MB46_06245 450c7a7379cc037f729e20ddad8f52c9 116 Gene3D G3DSA:1.10.10.10 2 115 4.3E-34 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_06245 450c7a7379cc037f729e20ddad8f52c9 116 SUPERFAMILY SSF46785 6 104 7.27E-22 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_18600 d477d5a8ff8f1e439ce3b441c734a0c9 262 SUPERFAMILY SSF55729 84 254 3.66E-20 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase MB46_18600 d477d5a8ff8f1e439ce3b441c734a0c9 262 Gene3D G3DSA:3.40.630.30 11 256 1.4E-31 T 14-10-2018 MB46_02120 df5cdebbbf4d7f7acb58a25cebbf75c6 401 Pfam PF02687 FtsX-like permease family 302 392 7.3E-8 T 14-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 MB46_02120 df5cdebbbf4d7f7acb58a25cebbf75c6 401 Pfam PF12704 MacB-like periplasmic core domain 23 243 3.6E-9 T 14-10-2018 IPR025857 MacB-like periplasmic core domain MB46_06295 9f2ef4ce6c8bf2caef73e74b068f08a3 343 Gene3D G3DSA:3.40.50.1100 56 160 1.2E-77 T 14-10-2018 MB46_06295 9f2ef4ce6c8bf2caef73e74b068f08a3 343 SUPERFAMILY SSF53686 23 323 7.6E-67 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme MB46_06295 9f2ef4ce6c8bf2caef73e74b068f08a3 343 Gene3D G3DSA:3.40.50.1100 25 312 1.2E-77 T 14-10-2018 MB46_06295 9f2ef4ce6c8bf2caef73e74b068f08a3 343 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 24 304 1.7E-45 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme MB46_09365 f8e3974f8dec42ba046c221417ba3f7b 476 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 119 452 2.9E-111 T 14-10-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MB46_09365 f8e3974f8dec42ba046c221417ba3f7b 476 SMART SM00846 117 278 2.7E-53 T 14-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MB46_09365 f8e3974f8dec42ba046c221417ba3f7b 476 SUPERFAMILY SSF51735 118 294 5.62E-44 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_09365 f8e3974f8dec42ba046c221417ba3f7b 476 Gene3D G3DSA:3.40.50.720 119 453 2.2E-113 T 14-10-2018 MB46_09365 f8e3974f8dec42ba046c221417ba3f7b 476 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 283 440 7.7E-49 T 14-10-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MB46_09365 f8e3974f8dec42ba046c221417ba3f7b 476 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 299 315 3.0E-17 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MB46_09365 f8e3974f8dec42ba046c221417ba3f7b 476 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 397 412 3.0E-17 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MB46_09365 f8e3974f8dec42ba046c221417ba3f7b 476 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 272 290 3.0E-17 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MB46_09365 f8e3974f8dec42ba046c221417ba3f7b 476 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 355 372 3.0E-17 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MB46_09365 f8e3974f8dec42ba046c221417ba3f7b 476 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 236 249 3.0E-17 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MB46_09365 f8e3974f8dec42ba046c221417ba3f7b 476 SUPERFAMILY SSF55347 278 441 3.57E-55 T 14-10-2018 MB46_09365 f8e3974f8dec42ba046c221417ba3f7b 476 Gene3D G3DSA:3.30.360.10 277 442 2.2E-113 T 14-10-2018 MB46_09365 f8e3974f8dec42ba046c221417ba3f7b 476 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 118 228 3.4E-20 T 14-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MB46_09365 f8e3974f8dec42ba046c221417ba3f7b 476 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 276 283 - T 14-10-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MB46_02815 2cdd4197c63a9c587fb7ea2f5c6c2669 138 Pfam PF05610 Protein of unknown function (DUF779) 31 129 8.9E-46 T 14-10-2018 IPR008497 Protein of unknown function DUF779 MB46_02815 2cdd4197c63a9c587fb7ea2f5c6c2669 138 PIRSF PIRSF009151 8 136 1.4E-52 T 14-10-2018 IPR008497 Protein of unknown function DUF779 MB46_06510 1a0661641537fe1ec5d7c6bf6f36da76 441 Gene3D G3DSA:1.20.1250.20 21 437 1.3E-52 T 14-10-2018 MB46_06510 1a0661641537fe1ec5d7c6bf6f36da76 441 ProSitePatterns PS00217 Sugar transport proteins signature 2. 135 160 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MB46_06510 1a0661641537fe1ec5d7c6bf6f36da76 441 Pfam PF00083 Sugar (and other) transporter 25 236 8.2E-20 T 14-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 MB46_06510 1a0661641537fe1ec5d7c6bf6f36da76 441 SUPERFAMILY SSF103473 11 429 1.7E-52 T 14-10-2018 IPR036259 MFS transporter superfamily MB46_11035 473ec00851731bfa7962aad563bd3e41 349 Pfam PF00107 Zinc-binding dehydrogenase 187 310 4.0E-20 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 MB46_11035 473ec00851731bfa7962aad563bd3e41 349 SMART SM00829 11 344 3.6E-6 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MB46_11035 473ec00851731bfa7962aad563bd3e41 349 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 14-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 MB46_11035 473ec00851731bfa7962aad563bd3e41 349 SUPERFAMILY SSF50129 10 172 4.87E-50 T 14-10-2018 IPR011032 GroES-like superfamily MB46_11035 473ec00851731bfa7962aad563bd3e41 349 Gene3D G3DSA:3.40.50.720 161 316 5.4E-130 T 14-10-2018 MB46_11035 473ec00851731bfa7962aad563bd3e41 349 Gene3D G3DSA:3.90.180.10 14 344 5.4E-130 T 14-10-2018 MB46_11035 473ec00851731bfa7962aad563bd3e41 349 SUPERFAMILY SSF51735 150 314 1.38E-40 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_11035 473ec00851731bfa7962aad563bd3e41 349 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 145 2.0E-27 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MB46_11035 473ec00851731bfa7962aad563bd3e41 349 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 180 208 - T 14-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 MB46_14460 c10b6a787e6333139b20aba18a5f846e 709 SUPERFAMILY SSF53720 6 521 4.84E-70 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 MB46_14460 c10b6a787e6333139b20aba18a5f846e 709 Pfam PF00171 Aldehyde dehydrogenase family 22 513 2.2E-54 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 MB46_14460 c10b6a787e6333139b20aba18a5f846e 709 Gene3D G3DSA:3.40.605.10 19 506 6.3E-134 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 MB46_14460 c10b6a787e6333139b20aba18a5f846e 709 Pfam PF01575 MaoC like domain 578 666 7.8E-18 T 14-10-2018 IPR002539 MaoC-like dehydratase domain MB46_14460 c10b6a787e6333139b20aba18a5f846e 709 Gene3D G3DSA:3.40.309.10 267 494 6.3E-134 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 MB46_14460 c10b6a787e6333139b20aba18a5f846e 709 SUPERFAMILY SSF54637 558 705 1.65E-31 T 14-10-2018 IPR029069 HotDog domain superfamily MB46_14460 c10b6a787e6333139b20aba18a5f846e 709 TIGRFAM TIGR02278 PaaN-DH: phenylacetic acid degradation protein paaN 10 703 0.0 T 14-10-2018 IPR011966 Phenylacetic acid degradation protein PaaN KEGG: 00360+3.3.2.12+1.2.1.91 MB46_14460 c10b6a787e6333139b20aba18a5f846e 709 Gene3D G3DSA:3.10.129.10 561 707 2.3E-35 T 14-10-2018 MB46_15435 35633a9ab79d115972b01e8c469f9b79 472 Pfam PF07690 Major Facilitator Superfamily 25 300 6.0E-28 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MB46_15435 35633a9ab79d115972b01e8c469f9b79 472 SUPERFAMILY SSF103473 17 466 1.83E-46 T 14-10-2018 IPR036259 MFS transporter superfamily MB46_15435 35633a9ab79d115972b01e8c469f9b79 472 Gene3D G3DSA:1.20.1250.20 268 471 2.3E-10 T 14-10-2018 MB46_15435 35633a9ab79d115972b01e8c469f9b79 472 Gene3D G3DSA:1.20.1250.20 12 267 6.6E-34 T 14-10-2018 MB46_17355 4309f4dfc9984f0263940005fb6cd356 324 SUPERFAMILY SSF161098 85 311 4.32E-49 T 14-10-2018 IPR035906 MetI-like superfamily MB46_17355 4309f4dfc9984f0263940005fb6cd356 324 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 117 312 2.5E-16 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_17355 4309f4dfc9984f0263940005fb6cd356 324 Gene3D G3DSA:1.10.3720.10 83 323 4.1E-56 T 14-10-2018 IPR035906 MetI-like superfamily MB46_15285 59c8bb660a0a801ad44dd35a14d7bf71 253 Pfam PF00106 short chain dehydrogenase 5 191 6.8E-35 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_15285 59c8bb660a0a801ad44dd35a14d7bf71 253 Gene3D G3DSA:3.40.50.720 1 249 2.7E-51 T 14-10-2018 MB46_15285 59c8bb660a0a801ad44dd35a14d7bf71 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 8.2E-25 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_15285 59c8bb660a0a801ad44dd35a14d7bf71 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 8.2E-25 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_15285 59c8bb660a0a801ad44dd35a14d7bf71 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 8.2E-25 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_15285 59c8bb660a0a801ad44dd35a14d7bf71 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 8.2E-25 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_15285 59c8bb660a0a801ad44dd35a14d7bf71 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 8.2E-25 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_15285 59c8bb660a0a801ad44dd35a14d7bf71 253 PIRSF PIRSF000126 1 249 2.5E-56 T 14-10-2018 MB46_15285 59c8bb660a0a801ad44dd35a14d7bf71 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 1.0E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_15285 59c8bb660a0a801ad44dd35a14d7bf71 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 1.0E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_15285 59c8bb660a0a801ad44dd35a14d7bf71 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 1.0E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_15285 59c8bb660a0a801ad44dd35a14d7bf71 253 SUPERFAMILY SSF51735 2 226 2.76E-48 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_15480 7273f67251793b7812e3fe072a81609a 319 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 39 54 - T 14-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MB46_15480 7273f67251793b7812e3fe072a81609a 319 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 73 86 - T 14-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MB46_15480 7273f67251793b7812e3fe072a81609a 319 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 39 297 2.2E-87 T 14-10-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 MB46_15480 7273f67251793b7812e3fe072a81609a 319 SUPERFAMILY SSF51717 31 299 6.67E-89 T 14-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MB46_15480 7273f67251793b7812e3fe072a81609a 319 Gene3D G3DSA:3.20.20.20 13 307 2.3E-103 T 14-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MB46_15480 7273f67251793b7812e3fe072a81609a 319 Pfam PF00809 Pterin binding enzyme 40 284 2.0E-79 T 14-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MB46_05215 419628508adfad924c0df077c570686f 244 SUPERFAMILY SSF51735 10 240 2.96E-78 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_05215 419628508adfad924c0df077c570686f 244 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 21 240 2.0E-56 T 14-10-2018 MB46_05215 419628508adfad924c0df077c570686f 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 2.0E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_05215 419628508adfad924c0df077c570686f 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 138 2.0E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_05215 419628508adfad924c0df077c570686f 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 77 88 2.0E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_05215 419628508adfad924c0df077c570686f 244 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 12 186 1.2E-7 T 14-10-2018 MB46_05215 419628508adfad924c0df077c570686f 244 Gene3D G3DSA:3.40.50.720 3 244 1.4E-81 T 14-10-2018 MB46_05215 419628508adfad924c0df077c570686f 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 3.3E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_05215 419628508adfad924c0df077c570686f 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 204 224 3.3E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_05215 419628508adfad924c0df077c570686f 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 3.3E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_05215 419628508adfad924c0df077c570686f 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 3.3E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_05215 419628508adfad924c0df077c570686f 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 3.3E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_05215 419628508adfad924c0df077c570686f 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 3.3E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_14620 b28921b0ed0f2ea25561b82c698eeada 161 Pfam PF07883 Cupin domain 47 107 1.6E-12 T 14-10-2018 IPR013096 Cupin 2, conserved barrel MB46_14620 b28921b0ed0f2ea25561b82c698eeada 161 SUPERFAMILY SSF51182 10 129 7.36E-20 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily MB46_14620 b28921b0ed0f2ea25561b82c698eeada 161 Gene3D G3DSA:2.60.120.10 2 153 2.0E-27 T 14-10-2018 IPR014710 RmlC-like jelly roll fold MB46_04355 8e77b942c62c703feed65909f5eb544f 170 SUPERFAMILY SSF55811 6 138 1.35E-22 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 MB46_04355 8e77b942c62c703feed65909f5eb544f 170 Gene3D G3DSA:3.90.79.10 2 157 9.2E-37 T 14-10-2018 MB46_04355 8e77b942c62c703feed65909f5eb544f 170 Pfam PF00293 NUDIX domain 6 132 2.9E-10 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MB46_04355 8e77b942c62c703feed65909f5eb544f 170 PRINTS PR01403 7,8-dihydro-8-oxoguanine triphosphatase signature 107 125 2.4E-9 T 14-10-2018 IPR003563 7,8-dihydro-8-oxoguanine triphosphatase GO:0006281|GO:0008413 MetaCyc: PWY-6502|Reactome: R-HSA-2393930 MB46_04355 8e77b942c62c703feed65909f5eb544f 170 PRINTS PR01403 7,8-dihydro-8-oxoguanine triphosphatase signature 23 39 2.4E-9 T 14-10-2018 IPR003563 7,8-dihydro-8-oxoguanine triphosphatase GO:0006281|GO:0008413 MetaCyc: PWY-6502|Reactome: R-HSA-2393930 MB46_04355 8e77b942c62c703feed65909f5eb544f 170 PRINTS PR01403 7,8-dihydro-8-oxoguanine triphosphatase signature 65 86 2.4E-9 T 14-10-2018 IPR003563 7,8-dihydro-8-oxoguanine triphosphatase GO:0006281|GO:0008413 MetaCyc: PWY-6502|Reactome: R-HSA-2393930 MB46_04355 8e77b942c62c703feed65909f5eb544f 170 PRINTS PR01403 7,8-dihydro-8-oxoguanine triphosphatase signature 126 144 2.4E-9 T 14-10-2018 IPR003563 7,8-dihydro-8-oxoguanine triphosphatase GO:0006281|GO:0008413 MetaCyc: PWY-6502|Reactome: R-HSA-2393930 MB46_15465 68863415ece891e4088e8a32da0a5d0b 167 Pfam PF11377 Protein of unknown function (DUF3180) 9 145 2.0E-33 T 14-10-2018 IPR021517 Protein of unknown function DUF3180 MB46_12130 5cf8f6e098cbc6f4f2bd887e2087b123 689 SUPERFAMILY SSF52540 18 219 7.59E-11 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_12130 5cf8f6e098cbc6f4f2bd887e2087b123 689 Pfam PF07693 KAP family P-loop domain 25 296 1.3E-36 T 14-10-2018 IPR011646 KAP family P-loop domain MB46_13680 2542673d5895d98121cbc554ff3e8c98 191 PRINTS PR00070 Dihydrofolate reductase signature 40 48 8.5E-16 T 14-10-2018 MB46_13680 2542673d5895d98121cbc554ff3e8c98 191 PRINTS PR00070 Dihydrofolate reductase signature 53 64 8.5E-16 T 14-10-2018 MB46_13680 2542673d5895d98121cbc554ff3e8c98 191 PRINTS PR00070 Dihydrofolate reductase signature 114 128 8.5E-16 T 14-10-2018 MB46_13680 2542673d5895d98121cbc554ff3e8c98 191 PRINTS PR00070 Dihydrofolate reductase signature 26 36 8.5E-16 T 14-10-2018 MB46_13680 2542673d5895d98121cbc554ff3e8c98 191 Gene3D G3DSA:3.40.430.10 10 189 3.9E-53 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 MB46_13680 2542673d5895d98121cbc554ff3e8c98 191 Pfam PF00186 Dihydrofolate reductase 15 182 6.3E-47 T 14-10-2018 IPR001796 Dihydrofolate reductase domain GO:0004146|GO:0046654|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 MB46_13680 2542673d5895d98121cbc554ff3e8c98 191 PIRSF PIRSF000194 10 185 8.8E-50 T 14-10-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0046654|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614 MB46_13680 2542673d5895d98121cbc554ff3e8c98 191 SUPERFAMILY SSF53597 15 183 6.41E-50 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 MB46_17765 da286fdbe63ed1bfd23cdd63a6e0f4b4 185 Gene3D G3DSA:2.40.128.110 15 185 1.5E-50 T 14-10-2018 IPR036761 Lipid/polyisoprenoid-binding, YceI-like superfamily MB46_17765 da286fdbe63ed1bfd23cdd63a6e0f4b4 185 Pfam PF04264 YceI-like domain 16 181 2.1E-44 T 14-10-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like MB46_17765 da286fdbe63ed1bfd23cdd63a6e0f4b4 185 SUPERFAMILY SSF101874 14 184 4.32E-52 T 14-10-2018 IPR036761 Lipid/polyisoprenoid-binding, YceI-like superfamily MB46_17765 da286fdbe63ed1bfd23cdd63a6e0f4b4 185 SMART SM00867 15 182 7.5E-66 T 14-10-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like MB46_00780 89c9ea6a18089b286599289aca3ba38b 281 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 12 247 8.5E-18 T 14-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 MB46_00780 89c9ea6a18089b286599289aca3ba38b 281 Gene3D G3DSA:3.40.50.1000 12 274 1.6E-40 T 14-10-2018 IPR023214 HAD superfamily MB46_00780 89c9ea6a18089b286599289aca3ba38b 281 SUPERFAMILY SSF56784 7 278 1.68E-37 T 14-10-2018 IPR036412 HAD-like superfamily MB46_00780 89c9ea6a18089b286599289aca3ba38b 281 Gene3D G3DSA:3.30.1240.10 87 204 1.6E-40 T 14-10-2018 MB46_00780 89c9ea6a18089b286599289aca3ba38b 281 Pfam PF08282 haloacid dehalogenase-like hydrolase 13 274 1.2E-33 T 14-10-2018 MB46_03975 83d5b9e532eb003fef10a04ff84b8127 233 Pfam PF00117 Glutamine amidotransferase class-I 17 216 5.4E-19 T 14-10-2018 IPR017926 Glutamine amidotransferase MB46_03975 83d5b9e532eb003fef10a04ff84b8127 233 PIRSF PIRSF000495 13 222 1.2E-61 T 14-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 MB46_03975 83d5b9e532eb003fef10a04ff84b8127 233 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 15 218 3.5E-59 T 14-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 MB46_03975 83d5b9e532eb003fef10a04ff84b8127 233 Gene3D G3DSA:3.40.50.880 10 231 2.1E-67 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like MB46_03975 83d5b9e532eb003fef10a04ff84b8127 233 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 14 219 31.875 T 14-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 MB46_03975 83d5b9e532eb003fef10a04ff84b8127 233 SUPERFAMILY SSF52317 14 218 2.36E-52 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like MB46_05955 1ffccaa80833425953c5a9ad8795f054 392 TIGRFAM TIGR04021 LLM_DMSO2_sfnG: dimethyl sulfone monooxygenase SfnG 15 367 8.0E-186 T 14-10-2018 IPR024014 FMNH(2)-dependent dimethylsulfone monooxygenase SfnG KEGG: 00920+1.14.14.35|MetaCyc: PWY-6059 MB46_05955 1ffccaa80833425953c5a9ad8795f054 392 Gene3D G3DSA:3.20.20.30 12 370 8.1E-99 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 MB46_05955 1ffccaa80833425953c5a9ad8795f054 392 SUPERFAMILY SSF51679 14 365 1.57E-83 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 MB46_05955 1ffccaa80833425953c5a9ad8795f054 392 Pfam PF00296 Luciferase-like monooxygenase 16 338 4.6E-72 T 14-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MB46_15330 b3be748d9ebfdf1f2b4fedda6f75cf76 315 Gene3D G3DSA:1.10.3720.10 66 310 1.1E-30 T 14-10-2018 IPR035906 MetI-like superfamily MB46_15330 b3be748d9ebfdf1f2b4fedda6f75cf76 315 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 92 305 9.1E-16 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_15330 b3be748d9ebfdf1f2b4fedda6f75cf76 315 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 22 308 3.2E-78 T 14-10-2018 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 MB46_15330 b3be748d9ebfdf1f2b4fedda6f75cf76 315 SUPERFAMILY SSF161098 34 304 1.5E-29 T 14-10-2018 IPR035906 MetI-like superfamily MB46_10075 7c56dff5f476467790fee4905050df24 114 TIGRFAM TIGR03462 CarR_dom_SF: lycopene cyclase domain 1 90 3.1E-15 T 14-10-2018 IPR017825 Lycopene cyclase domain GO:0016872 KEGG: 00906+2.5.1.32+5.5.1.19|MetaCyc: PWY-5943|MetaCyc: PWY-5947|MetaCyc: PWY-6279|MetaCyc: PWY-7591|MetaCyc: PWY-7938|MetaCyc: PWY-7939|MetaCyc: PWY-7947 MB46_04090 cca7e3d66b35a08c4bd390257a2ec725 321 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 60 71 4.7E-11 T 14-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 MB46_04090 cca7e3d66b35a08c4bd390257a2ec725 321 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 33 41 4.7E-11 T 14-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 MB46_04090 cca7e3d66b35a08c4bd390257a2ec725 321 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 108 122 4.7E-11 T 14-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 MB46_04090 cca7e3d66b35a08c4bd390257a2ec725 321 Pfam PF00561 alpha/beta hydrolase fold 32 184 1.5E-23 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MB46_04090 cca7e3d66b35a08c4bd390257a2ec725 321 PIRSF PIRSF006431 1 314 3.5E-92 T 14-10-2018 IPR005944 Proline iminopeptidase GO:0004177|GO:0005737|GO:0006508 KEGG: 00330+3.4.11.5 MB46_04090 cca7e3d66b35a08c4bd390257a2ec725 321 Gene3D G3DSA:3.40.50.1820 2 312 1.0E-73 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_04090 cca7e3d66b35a08c4bd390257a2ec725 321 SUPERFAMILY SSF53474 12 299 2.45E-45 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_08245 3fe30ca6dd111dfc8a1f9e0f11504198 403 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 353 377 - T 14-10-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MB46_08245 3fe30ca6dd111dfc8a1f9e0f11504198 403 Pfam PF01098 Cell cycle protein 46 394 5.5E-84 T 14-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MB46_16500 c1a499afc4278b78a9768a09e08d918f 336 Pfam PF02698 DUF218 domain 159 303 3.4E-27 T 14-10-2018 IPR003848 Domain of unknown function DUF218 MB46_07640 047b509230aa5b2acb87bdfd5aba351f 257 Pfam PF00218 Indole-3-glycerol phosphate synthase 3 245 1.9E-76 T 14-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 MB46_07640 047b509230aa5b2acb87bdfd5aba351f 257 Gene3D G3DSA:3.20.20.70 1 257 1.7E-92 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MB46_07640 047b509230aa5b2acb87bdfd5aba351f 257 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 42 60 - T 14-10-2018 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48 MB46_07640 047b509230aa5b2acb87bdfd5aba351f 257 SUPERFAMILY SSF51366 4 247 5.46E-73 T 14-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 MB46_04675 5b9ed77816955d1570371157928cf90b 341 Gene3D G3DSA:3.40.50.1820 47 338 7.2E-38 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_04675 5b9ed77816955d1570371157928cf90b 341 SUPERFAMILY SSF53474 55 339 5.9E-31 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_04675 5b9ed77816955d1570371157928cf90b 341 Pfam PF12146 Serine aminopeptidase, S33 64 277 4.3E-17 T 14-10-2018 IPR022742 Serine aminopeptidase, S33 MB46_02830 9fed077f8e2bfe2dcd71e4696a565faa 151 Gene3D G3DSA:1.10.3210.10 3 150 1.4E-21 T 14-10-2018 MB46_02830 9fed077f8e2bfe2dcd71e4696a565faa 151 SMART SM00471 26 130 1.1E-5 T 14-10-2018 IPR003607 HD/PDEase domain MB46_02830 9fed077f8e2bfe2dcd71e4696a565faa 151 Pfam PF13328 HD domain 11 97 4.1E-7 T 14-10-2018 IPR003607 HD/PDEase domain MB46_02830 9fed077f8e2bfe2dcd71e4696a565faa 151 SUPERFAMILY SSF109604 5 138 3.49E-23 T 14-10-2018 MB46_05800 12c0e6281662735f0ca0466a2c45cc92 310 Gene3D G3DSA:3.40.190.10 60 259 2.9E-45 T 14-10-2018 MB46_05800 12c0e6281662735f0ca0466a2c45cc92 310 SMART SM00062 51 274 0.0097 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MB46_05800 12c0e6281662735f0ca0466a2c45cc92 310 SUPERFAMILY SSF53850 50 297 2.25E-35 T 14-10-2018 MB46_05800 12c0e6281662735f0ca0466a2c45cc92 310 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 54 281 2.2E-47 T 14-10-2018 MB46_05800 12c0e6281662735f0ca0466a2c45cc92 310 Gene3D G3DSA:3.40.190.10 137 236 2.9E-45 T 14-10-2018 MB46_05800 12c0e6281662735f0ca0466a2c45cc92 310 TIGRFAM TIGR01098 3A0109s03R: phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein 15 260 1.9E-47 T 14-10-2018 IPR005770 Phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein GO:0043190|GO:0055085 MB46_04460 89bae3f21c2dbc7af94d18d043ff0403 367 SUPERFAMILY SSF48179 177 264 2.72E-22 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MB46_04460 89bae3f21c2dbc7af94d18d043ff0403 367 Gene3D G3DSA:1.10.3660.10 180 284 8.8E-23 T 14-10-2018 MB46_04460 89bae3f21c2dbc7af94d18d043ff0403 367 Pfam PF02153 Prephenate dehydrogenase 23 265 9.9E-50 T 14-10-2018 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 MB46_04460 89bae3f21c2dbc7af94d18d043ff0403 367 SUPERFAMILY SSF55021 294 346 1.15E-5 T 14-10-2018 MB46_04460 89bae3f21c2dbc7af94d18d043ff0403 367 Gene3D G3DSA:3.40.50.720 9 179 3.3E-37 T 14-10-2018 MB46_04460 89bae3f21c2dbc7af94d18d043ff0403 367 SUPERFAMILY SSF51735 10 173 3.74E-26 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_06455 44f0e3f8c10f422d815abaa486d98e8a 313 Gene3D G3DSA:1.10.3720.10 85 305 2.3E-22 T 14-10-2018 IPR035906 MetI-like superfamily MB46_06455 44f0e3f8c10f422d815abaa486d98e8a 313 SUPERFAMILY SSF161098 91 296 1.57E-16 T 14-10-2018 IPR035906 MetI-like superfamily MB46_06455 44f0e3f8c10f422d815abaa486d98e8a 313 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 311 3.1E-32 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_00910 429ca35b6bca25e4b91e23dee03daa2b 198 Gene3D G3DSA:3.30.70.2390 111 194 5.0E-9 T 14-10-2018 MB46_00910 429ca35b6bca25e4b91e23dee03daa2b 198 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 113 195 2.7E-11 T 14-10-2018 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain MB46_07890 25e0b9e3ea2ce903a6d61775b9d3087b 482 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 321 472 1.0E-11 T 14-10-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 MB46_07890 25e0b9e3ea2ce903a6d61775b9d3087b 482 Gene3D G3DSA:2.40.50.140 5 86 1.6E-16 T 14-10-2018 MB46_07890 25e0b9e3ea2ce903a6d61775b9d3087b 482 SUPERFAMILY SSF50249 16 75 1.09E-10 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold MB46_07890 25e0b9e3ea2ce903a6d61775b9d3087b 482 Gene3D G3DSA:3.40.1350.30 160 294 3.6E-56 T 14-10-2018 MB46_07890 25e0b9e3ea2ce903a6d61775b9d3087b 482 Gene3D G3DSA:3.40.50.150 99 469 3.6E-56 T 14-10-2018 MB46_07890 25e0b9e3ea2ce903a6d61775b9d3087b 482 SUPERFAMILY SSF53335 95 474 2.48E-39 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MB46_07330 f0ab1e38d1641d390acb8d9a29b3ef65 336 Gene3D G3DSA:3.40.50.720 142 284 2.5E-101 T 14-10-2018 MB46_07330 f0ab1e38d1641d390acb8d9a29b3ef65 336 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 126 2.1E-7 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MB46_07330 f0ab1e38d1641d390acb8d9a29b3ef65 336 Gene3D G3DSA:3.90.180.10 17 327 2.5E-101 T 14-10-2018 MB46_07330 f0ab1e38d1641d390acb8d9a29b3ef65 336 SUPERFAMILY SSF51735 137 313 1.04E-47 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_07330 f0ab1e38d1641d390acb8d9a29b3ef65 336 SMART SM00829 10 333 9.2E-29 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MB46_07330 f0ab1e38d1641d390acb8d9a29b3ef65 336 Pfam PF00107 Zinc-binding dehydrogenase 171 298 2.8E-32 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 MB46_07330 f0ab1e38d1641d390acb8d9a29b3ef65 336 SUPERFAMILY SSF50129 1 165 7.41E-34 T 14-10-2018 IPR011032 GroES-like superfamily MB46_04395 bc706b1294d169b0d910569fb5817df8 607 Pfam PF06276 Ferric iron reductase FhuF-like transporter 427 583 4.1E-40 T 14-10-2018 IPR022770 Ferric iron reductase FhuF domain MB46_04395 bc706b1294d169b0d910569fb5817df8 607 Pfam PF04183 IucA / IucC family 156 405 7.3E-74 T 14-10-2018 IPR007310 Aerobactin siderophore biosynthesis, IucA/IucC, N-terminal GO:0019290 MB46_04395 bc706b1294d169b0d910569fb5817df8 607 Gene3D G3DSA:1.10.510.40 394 601 2.6E-71 T 14-10-2018 MB46_04395 bc706b1294d169b0d910569fb5817df8 607 Gene3D G3DSA:1.10.274.90 2 134 4.0E-45 T 14-10-2018 MB46_03430 2af9cb012351ff7dfe47736274b44d6d 163 Gene3D G3DSA:1.10.10.60 65 104 3.9E-5 T 14-10-2018 MB46_09835 375e7e9539078d99dde0154773d8e54e 262 SUPERFAMILY SSF55729 73 258 2.06E-22 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase MB46_09835 375e7e9539078d99dde0154773d8e54e 262 Gene3D G3DSA:3.40.630.30 8 258 1.4E-35 T 14-10-2018 MB46_09835 375e7e9539078d99dde0154773d8e54e 262 Pfam PF00583 Acetyltransferase (GNAT) family 152 246 7.8E-5 T 14-10-2018 IPR000182 GNAT domain MB46_02400 a3e6cb79b6ce7904f9f15f3dc0f2fe84 447 Pfam PF01882 Protein of unknown function DUF58 199 299 2.2E-19 T 14-10-2018 IPR002881 Domain of unknown function DUF58 MB46_15550 a57d0235b84c257aa1bb3f3ef36909b1 478 Gene3D G3DSA:3.40.710.10 273 474 4.6E-45 T 14-10-2018 MB46_15550 a57d0235b84c257aa1bb3f3ef36909b1 478 SUPERFAMILY SSF56601 89 476 8.2E-53 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like MB46_15550 a57d0235b84c257aa1bb3f3ef36909b1 478 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 366 380 1.2E-17 T 14-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 MB46_15550 a57d0235b84c257aa1bb3f3ef36909b1 478 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 112 131 1.2E-17 T 14-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 MB46_15550 a57d0235b84c257aa1bb3f3ef36909b1 478 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 294 316 1.2E-17 T 14-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 MB46_15550 a57d0235b84c257aa1bb3f3ef36909b1 478 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 433 446 1.2E-17 T 14-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 MB46_15550 a57d0235b84c257aa1bb3f3ef36909b1 478 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 351 365 1.2E-17 T 14-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 MB46_15550 a57d0235b84c257aa1bb3f3ef36909b1 478 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 246 475 1.3E-40 T 14-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 MB46_15550 a57d0235b84c257aa1bb3f3ef36909b1 478 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 78 241 5.1E-23 T 14-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 MB46_15550 a57d0235b84c257aa1bb3f3ef36909b1 478 Gene3D G3DSA:3.40.710.10 73 211 1.7E-9 T 14-10-2018 MB46_01615 db8b67406f78ec43a365fbbd7bbde227 450 ProSitePatterns PS00217 Sugar transport proteins signature 2. 123 148 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MB46_01615 db8b67406f78ec43a365fbbd7bbde227 450 Pfam PF07690 Major Facilitator Superfamily 33 406 7.0E-46 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MB46_01615 db8b67406f78ec43a365fbbd7bbde227 450 SUPERFAMILY SSF103473 16 450 7.85E-78 T 14-10-2018 IPR036259 MFS transporter superfamily MB46_01615 db8b67406f78ec43a365fbbd7bbde227 450 Gene3D G3DSA:1.20.1250.20 23 450 8.3E-86 T 14-10-2018 MB46_01615 db8b67406f78ec43a365fbbd7bbde227 450 ProSitePatterns PS00216 Sugar transport proteins signature 1. 319 336 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MB46_09385 81bdc677b27b5c0d051e8478d370fa19 174 Gene3D G3DSA:3.30.1060.10 1 163 2.3E-58 T 14-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 MB46_09385 81bdc677b27b5c0d051e8478d370fa19 174 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 1 158 32.422 T 14-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 MB46_09385 81bdc677b27b5c0d051e8478d370fa19 174 Pfam PF01625 Peptide methionine sulfoxide reductase 4 154 3.7E-54 T 14-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 MB46_09385 81bdc677b27b5c0d051e8478d370fa19 174 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 3 153 1.6E-52 T 14-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 MB46_09385 81bdc677b27b5c0d051e8478d370fa19 174 SUPERFAMILY SSF55068 1 164 6.28E-64 T 14-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 MB46_15765 c2641762bd6e7c30a7d2c1d1aeb58cb0 368 Pfam PF13588 Type I restriction enzyme R protein N terminus (HSDR_N) 194 260 4.1E-6 T 14-10-2018 IPR029464 Type I restriction enzyme R protein, N-terminal domain MB46_09960 5920617ff43ef62413d3df33465fdad5 581 SUPERFAMILY SSF52540 52 250 4.54E-17 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_09960 5920617ff43ef62413d3df33465fdad5 581 Pfam PF00350 Dynamin family 61 195 9.2E-10 T 14-10-2018 IPR022812 Dynamin superfamily MB46_09960 5920617ff43ef62413d3df33465fdad5 581 Gene3D G3DSA:3.40.50.300 55 250 7.5E-12 T 14-10-2018 MB46_02665 8c79a24302bc0b760094d71e05ae0d39 628 Pfam PF01522 Polysaccharide deacetylase 51 171 5.7E-15 T 14-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 MB46_02665 8c79a24302bc0b760094d71e05ae0d39 628 Gene3D G3DSA:3.20.20.370 47 279 2.2E-23 T 14-10-2018 MB46_02665 8c79a24302bc0b760094d71e05ae0d39 628 Gene3D G3DSA:2.60.120.260 338 498 4.7E-12 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily MB46_02665 8c79a24302bc0b760094d71e05ae0d39 628 SUPERFAMILY SSF88713 53 276 3.61E-24 T 14-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 MB46_07725 1f5d1d465aea3fdc0ac4a63cc4148c39 306 Gene3D G3DSA:3.10.25.10 205 302 1.9E-20 T 14-10-2018 IPR037022 Formyl transferase, C-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MB46_07725 1f5d1d465aea3fdc0ac4a63cc4148c39 306 Gene3D G3DSA:3.40.50.170 1 203 8.0E-62 T 14-10-2018 MB46_07725 1f5d1d465aea3fdc0ac4a63cc4148c39 306 SUPERFAMILY SSF53328 1 195 3.66E-52 T 14-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MB46_07725 1f5d1d465aea3fdc0ac4a63cc4148c39 306 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 1 300 30.543 T 14-10-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 MB46_07725 1f5d1d465aea3fdc0ac4a63cc4148c39 306 SUPERFAMILY SSF50486 203 303 1.43E-22 T 14-10-2018 IPR011034 Formyl transferase-like, C-terminal domain superfamily GO:0003824 MB46_07725 1f5d1d465aea3fdc0ac4a63cc4148c39 306 Pfam PF02911 Formyl transferase, C-terminal domain 201 297 2.2E-20 T 14-10-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MB46_07725 1f5d1d465aea3fdc0ac4a63cc4148c39 306 Pfam PF00551 Formyl transferase 2 178 1.2E-30 T 14-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MB46_11700 2f3f50f6e20c0d1d5d2ef6d956e361a5 363 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 138 363 8.4E-42 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_11700 2f3f50f6e20c0d1d5d2ef6d956e361a5 363 SUPERFAMILY SSF161098 115 346 1.83E-16 T 14-10-2018 IPR035906 MetI-like superfamily MB46_12210 1c7b4037944cd6e625e60a1568341b86 658 Pfam PF02720 Domain of unknown function (DUF222) 10 226 1.2E-18 T 14-10-2018 IPR003870 Domain of unknown function DUF222 MB46_12210 1c7b4037944cd6e625e60a1568341b86 658 Pfam PF01844 HNH endonuclease 479 519 4.1E-5 T 14-10-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 MB46_12210 1c7b4037944cd6e625e60a1568341b86 658 SMART SM00507 463 515 1.4E-6 T 14-10-2018 IPR003615 HNH nuclease MB46_19620 e9333efbd424e98afeb26e3869e5f859 390 Pfam PF06772 Bacterial low temperature requirement A protein (LtrA) 14 375 6.5E-90 T 14-10-2018 IPR010640 Low temperature requirement A MB46_11590 95ae3833d8f568dcafc21a7fa00c5da4 213 SMART SM00858 47 110 0.0042 T 14-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 MB46_06850 36d695590b6f283d2539f3ac4b97f80b 292 Pfam PF13460 NAD(P)H-binding 7 184 2.2E-21 T 14-10-2018 IPR016040 NAD(P)-binding domain MB46_06850 36d695590b6f283d2539f3ac4b97f80b 292 Gene3D G3DSA:3.90.25.10 139 270 3.1E-83 T 14-10-2018 MB46_06850 36d695590b6f283d2539f3ac4b97f80b 292 Gene3D G3DSA:3.40.50.720 4 269 3.1E-83 T 14-10-2018 MB46_06850 36d695590b6f283d2539f3ac4b97f80b 292 SUPERFAMILY SSF51735 2 256 1.52E-57 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_05825 a8096f9b769fdea15dd069edb2fa6d5c 346 Pfam PF03824 High-affinity nickel-transport protein 52 336 2.9E-47 T 14-10-2018 IPR011541 Nickel/cobalt transporter, high-affinity GO:0015099|GO:0016021|GO:0035444|GO:0046872 MB46_08100 77cadd8f22e9f5d65b42f8821895cf55 61 Pfam PF05532 CsbD-like 5 57 1.0E-17 T 14-10-2018 IPR008462 CsbD-like domain MB46_08100 77cadd8f22e9f5d65b42f8821895cf55 61 Gene3D G3DSA:1.10.1470.10 4 61 2.1E-7 T 14-10-2018 IPR036629 YjbJ superfamily MB46_08100 77cadd8f22e9f5d65b42f8821895cf55 61 SUPERFAMILY SSF69047 5 60 2.35E-10 T 14-10-2018 IPR036629 YjbJ superfamily MB46_13175 f88e9c28084203c2a0746569f801753d 366 Gene3D G3DSA:1.10.10.10 5 62 3.7E-12 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_13175 f88e9c28084203c2a0746569f801753d 366 SUPERFAMILY SSF53067 69 361 2.43E-38 T 14-10-2018 MB46_13175 f88e9c28084203c2a0746569f801753d 366 SUPERFAMILY SSF46785 4 61 7.94E-11 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_13175 f88e9c28084203c2a0746569f801753d 366 Pfam PF00480 ROK family 70 358 7.7E-38 T 14-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 MB46_13175 f88e9c28084203c2a0746569f801753d 366 Gene3D G3DSA:3.30.420.40 73 186 6.9E-56 T 14-10-2018 MB46_13175 f88e9c28084203c2a0746569f801753d 366 Gene3D G3DSA:3.30.420.40 187 313 6.9E-56 T 14-10-2018 MB46_01045 f35b9e0d8de78e5d990b443c4f0c49e1 138 Gene3D G3DSA:3.90.79.10 2 132 6.4E-20 T 14-10-2018 MB46_01045 f35b9e0d8de78e5d990b443c4f0c49e1 138 Pfam PF00293 NUDIX domain 9 119 3.1E-16 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MB46_01045 f35b9e0d8de78e5d990b443c4f0c49e1 138 SUPERFAMILY SSF55811 6 121 7.85E-21 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 MB46_07225 0de65c80f68864a1f542d0aa49a14c8e 224 SUPERFAMILY SSF49503 16 86 2.44E-5 T 14-10-2018 IPR008972 Cupredoxin MB46_11535 1bd5e471a64175c2cdc1ddb30228b299 692 Pfam PF01757 Acyltransferase family 14 349 1.3E-21 T 14-10-2018 IPR002656 Acyltransferase 3 GO:0016747 MB46_06500 53c5da4f737479f9806938318b8ec332 458 Gene3D G3DSA:1.20.1250.20 19 447 6.1E-70 T 14-10-2018 MB46_06500 53c5da4f737479f9806938318b8ec332 458 Pfam PF07690 Major Facilitator Superfamily 65 385 4.9E-32 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MB46_06500 53c5da4f737479f9806938318b8ec332 458 SUPERFAMILY SSF103473 20 432 5.49E-67 T 14-10-2018 IPR036259 MFS transporter superfamily MB46_04980 413654e58269a0aa8daf0dac7198ad62 431 SUPERFAMILY SSF53474 25 275 2.01E-30 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_04980 413654e58269a0aa8daf0dac7198ad62 431 Pfam PF00561 alpha/beta hydrolase fold 55 200 2.0E-17 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MB46_04980 413654e58269a0aa8daf0dac7198ad62 431 Gene3D G3DSA:3.40.50.1820 35 429 2.3E-22 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_04980 413654e58269a0aa8daf0dac7198ad62 431 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 57 65 2.1E-9 T 14-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 MB46_04980 413654e58269a0aa8daf0dac7198ad62 431 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 145 159 2.1E-9 T 14-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 MB46_04980 413654e58269a0aa8daf0dac7198ad62 431 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 87 98 2.1E-9 T 14-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 MB46_02540 04671339dd23b87c8a9e43a99348a43f 440 Pfam PF00266 Aminotransferase class-V 40 422 6.6E-135 T 14-10-2018 IPR000192 Aminotransferase class V domain MB46_02540 04671339dd23b87c8a9e43a99348a43f 440 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 243 262 - T 14-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site MB46_02540 04671339dd23b87c8a9e43a99348a43f 440 Gene3D G3DSA:3.90.1150.10 23 424 5.9E-167 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MB46_02540 04671339dd23b87c8a9e43a99348a43f 440 TIGRFAM TIGR01979 sufS: cysteine desulfurase, SufS family 22 433 3.0E-168 T 14-10-2018 IPR010970 Cysteine desulfurase, SufS GO:0006534|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 MB46_02540 04671339dd23b87c8a9e43a99348a43f 440 SUPERFAMILY SSF53383 20 429 4.44E-119 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MB46_02540 04671339dd23b87c8a9e43a99348a43f 440 Gene3D G3DSA:3.40.640.10 51 322 5.9E-167 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MB46_05165 1caa4a76e8602ad08206b8534ea11c98 496 Pfam PF00501 AMP-binding enzyme 113 374 4.8E-30 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 MB46_05165 1caa4a76e8602ad08206b8534ea11c98 496 Gene3D G3DSA:3.40.50.12780 3 371 1.5E-48 T 14-10-2018 MB46_05165 1caa4a76e8602ad08206b8534ea11c98 496 Gene3D G3DSA:3.30.300.30 372 495 1.4E-14 T 14-10-2018 MB46_05165 1caa4a76e8602ad08206b8534ea11c98 496 SUPERFAMILY SSF56801 4 487 3.66E-70 T 14-10-2018 MB46_05165 1caa4a76e8602ad08206b8534ea11c98 496 ProSitePatterns PS00455 Putative AMP-binding domain signature. 114 125 - T 14-10-2018 IPR020845 AMP-binding, conserved site MB46_06875 d2e2e8d500ff30938a583335da558a76 264 Gene3D G3DSA:3.40.50.1820 2 258 6.8E-35 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_06875 d2e2e8d500ff30938a583335da558a76 264 SUPERFAMILY SSF53474 5 253 6.13E-30 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_06875 d2e2e8d500ff30938a583335da558a76 264 Pfam PF00326 Prolyl oligopeptidase family 87 251 3.2E-8 T 14-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 MB46_00530 91618e0bbe9da406e240ab12a36c30df 254 Pfam PF01614 Bacterial transcriptional regulator 125 237 3.3E-25 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal MB46_00530 91618e0bbe9da406e240ab12a36c30df 254 SUPERFAMILY SSF55781 87 251 2.68E-35 T 14-10-2018 MB46_00530 91618e0bbe9da406e240ab12a36c30df 254 Gene3D G3DSA:3.30.450.40 80 253 1.2E-38 T 14-10-2018 IPR029016 GAF-like domain superfamily MB46_00530 91618e0bbe9da406e240ab12a36c30df 254 Gene3D G3DSA:1.10.10.10 3 76 3.6E-5 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_18395 d388c76c88c1cd348ce623c83d02d633 195 Pfam PF13376 Bacteriocin-protection, YdeI or OmpD-Associated 127 185 1.0E-16 T 14-10-2018 MB46_02455 86f776111e273fb20813344c9e13059a 249 Gene3D G3DSA:3.40.960.10 145 245 5.6E-8 T 14-10-2018 MB46_00840 d57774b00464b3109e6a572decf52ee0 261 Pfam PF00378 Enoyl-CoA hydratase/isomerase 7 254 2.9E-39 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 MB46_00840 d57774b00464b3109e6a572decf52ee0 261 Gene3D G3DSA:3.90.226.10 1 199 1.9E-61 T 14-10-2018 MB46_00840 d57774b00464b3109e6a572decf52ee0 261 SUPERFAMILY SSF52096 2 254 2.49E-66 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MB46_00840 d57774b00464b3109e6a572decf52ee0 261 Gene3D G3DSA:1.10.12.10 200 258 2.4E-11 T 14-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal MB46_08465 390f813b5574b7a989661c8d1243e3ee 106 Gene3D G3DSA:1.10.8.50 1 106 2.4E-34 T 14-10-2018 MB46_08465 390f813b5574b7a989661c8d1243e3ee 106 SUPERFAMILY SSF46946 60 104 8.75E-7 T 14-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 MB46_18735 35564b1356981995f946dfa7429dd054 424 SUPERFAMILY SSF103473 15 404 3.4E-49 T 14-10-2018 IPR036259 MFS transporter superfamily MB46_18735 35564b1356981995f946dfa7429dd054 424 Gene3D G3DSA:1.20.1250.20 14 397 5.8E-42 T 14-10-2018 MB46_18735 35564b1356981995f946dfa7429dd054 424 Pfam PF05977 Transmembrane secretion effector 14 394 4.2E-56 T 14-10-2018 IPR010290 Transmembrane secretion effector MB46_14870 70284aeb3830f6751bbad17f4f120709 884 Pfam PF13088 BNR repeat-like domain 253 421 1.8E-13 T 14-10-2018 IPR011040 Sialidase KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 MB46_14870 70284aeb3830f6751bbad17f4f120709 884 SUPERFAMILY SSF50939 67 443 3.92E-75 T 14-10-2018 IPR036278 Sialidase superfamily KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 MB46_14870 70284aeb3830f6751bbad17f4f120709 884 Gene3D G3DSA:2.60.40.10 448 547 4.7E-5 T 14-10-2018 IPR013783 Immunoglobulin-like fold MB46_14870 70284aeb3830f6751bbad17f4f120709 884 Pfam PF10633 NPCBM-associated, NEW3 domain of alpha-galactosidase 459 531 1.1E-10 T 14-10-2018 IPR018905 Alpha-galactosidase, NEW3 domain MB46_14870 70284aeb3830f6751bbad17f4f120709 884 Gene3D G3DSA:2.120.10.10 45 447 7.8E-116 T 14-10-2018 MB46_03540 53c7fb5d724c1a91cdcf70acac15874e 122 Pfam PF04341 Protein of unknown function, DUF485 19 106 2.2E-34 T 14-10-2018 IPR007436 Protein of unknown function DUF485 MB46_17510 e4fe37e74ead87b6aff82cdfa9476b4c 468 Pfam PF02386 Cation transport protein 45 448 7.1E-54 T 14-10-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 MB46_04415 1c5d2b1aea6d14bd0366d4d964d6cdf1 231 SUPERFAMILY SSF52172 5 143 3.13E-27 T 14-10-2018 IPR011006 CheY-like superfamily MB46_04415 1c5d2b1aea6d14bd0366d4d964d6cdf1 231 PIRSF PIRSF006171 5 231 2.7E-62 T 14-10-2018 IPR024187 Signal transduction response regulator, citrate/malate metabolism GO:0000160|GO:0003700 MB46_04415 1c5d2b1aea6d14bd0366d4d964d6cdf1 231 Gene3D G3DSA:3.40.50.2300 5 151 1.7E-23 T 14-10-2018 MB46_04415 1c5d2b1aea6d14bd0366d4d964d6cdf1 231 Pfam PF00072 Response regulator receiver domain 9 123 1.4E-17 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MB46_04415 1c5d2b1aea6d14bd0366d4d964d6cdf1 231 SMART SM00448 7 123 2.7E-17 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MB46_18865 e44550addc3fd65fec96815ff86b8ad1 278 SUPERFAMILY SSF51556 3 276 1.91E-54 T 14-10-2018 IPR032466 Metal-dependent hydrolase MB46_18865 e44550addc3fd65fec96815ff86b8ad1 278 Gene3D G3DSA:3.20.20.140 2 278 1.7E-73 T 14-10-2018 MB46_18865 e44550addc3fd65fec96815ff86b8ad1 278 Pfam PF04909 Amidohydrolase 5 276 2.9E-35 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 MB46_14770 d8c4fd3e1c45099c75169f7bb8f78b7a 501 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 38 466 6.6E-84 T 14-10-2018 IPR001248 Purine-cytosine permease GO:0016020|GO:0022857|GO:0055085 MB46_14770 d8c4fd3e1c45099c75169f7bb8f78b7a 501 Gene3D G3DSA:1.10.4160.10 20 495 1.1E-105 T 14-10-2018 IPR038271 Purine-cytosine permease superfamily MB46_06140 450e9f0d62de7c4822bdfd41e4fde400 517 Gene3D G3DSA:1.10.10.2840 380 513 1.1E-9 T 14-10-2018 MB46_06140 450e9f0d62de7c4822bdfd41e4fde400 517 Pfam PF07905 Purine catabolism regulatory protein-like family 1 97 3.8E-24 T 14-10-2018 IPR012914 Purine catabolism PurC-like domain MB46_06140 450e9f0d62de7c4822bdfd41e4fde400 517 Pfam PF13556 PucR C-terminal helix-turn-helix domain 450 507 9.3E-14 T 14-10-2018 IPR025736 PucR C-terminal helix-turn-helix domain MB46_00110 cc06e9f31e167602835644e9690d17d3 71 SUPERFAMILY SSF46955 18 68 3.3E-8 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily MB46_00110 cc06e9f31e167602835644e9690d17d3 71 Pfam PF12728 Helix-turn-helix domain 18 68 6.5E-14 T 14-10-2018 MB46_00110 cc06e9f31e167602835644e9690d17d3 71 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 18 67 1.5E-11 T 14-10-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 MB46_11350 74eabba7d255e0c72551de8b12817661 124 Pfam PF07811 TadE-like protein 7 49 7.9E-8 T 14-10-2018 IPR012495 TadE-like MB46_10710 4cb7292582fa6edf6361b5356a30c83a 224 Pfam PF09335 SNARE associated Golgi protein 51 178 9.7E-23 T 14-10-2018 IPR032816 SNARE associated Golgi protein MB46_01975 25ce4f756eb06a001b89c50af5298641 298 Pfam PF09335 SNARE associated Golgi protein 40 164 1.3E-17 T 14-10-2018 IPR032816 SNARE associated Golgi protein MB46_18975 21a38df22288c5f4bc586ac5e02eed27 354 SUPERFAMILY SSF53850 48 341 4.21E-72 T 14-10-2018 MB46_18975 21a38df22288c5f4bc586ac5e02eed27 354 Pfam PF13343 Bacterial extracellular solute-binding protein 97 335 7.6E-29 T 14-10-2018 MB46_18975 21a38df22288c5f4bc586ac5e02eed27 354 Gene3D G3DSA:3.40.190.10 144 332 9.3E-105 T 14-10-2018 MB46_18975 21a38df22288c5f4bc586ac5e02eed27 354 PIRSF PIRSF002825 6 354 6.5E-81 T 14-10-2018 IPR026045 Ferric binding protein MB46_18975 21a38df22288c5f4bc586ac5e02eed27 354 Gene3D G3DSA:3.40.190.10 51 324 9.3E-105 T 14-10-2018 MB46_06715 a1e189aa6f13ef1a5aac8aff5321fdb5 156 Gene3D G3DSA:2.30.110.10 3 143 1.4E-37 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 MB46_06715 a1e189aa6f13ef1a5aac8aff5321fdb5 156 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 14 134 1.7E-25 T 14-10-2018 IPR024747 Pyridoxamine 5'-phosphate oxidase-related MB46_06715 a1e189aa6f13ef1a5aac8aff5321fdb5 156 SUPERFAMILY SSF50475 10 135 2.84E-27 T 14-10-2018 MB46_09820 f35fd913e45c0d3108aeb6c96bf455da 312 SUPERFAMILY SSF101473 4 192 3.4E-28 T 14-10-2018 IPR036117 DhaL domain superfamily GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 MB46_09820 f35fd913e45c0d3108aeb6c96bf455da 312 Pfam PF02734 DAK2 domain 20 189 4.7E-26 T 14-10-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 MB46_09820 f35fd913e45c0d3108aeb6c96bf455da 312 Gene3D G3DSA:1.25.40.340 1 194 7.2E-9 T 14-10-2018 IPR036117 DhaL domain superfamily GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 MB46_09820 f35fd913e45c0d3108aeb6c96bf455da 312 SMART SM01120 20 191 4.3E-32 T 14-10-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 MB46_12250 cc99f49dcf9da6b2df8dfe0888d14c38 444 PIRSF PIRSF000412 7 441 8.3E-155 T 14-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 MB46_12250 cc99f49dcf9da6b2df8dfe0888d14c38 444 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 240 256 - T 14-10-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 MB46_12250 cc99f49dcf9da6b2df8dfe0888d14c38 444 Pfam PF00464 Serine hydroxymethyltransferase 27 408 8.5E-163 T 14-10-2018 IPR039429 Serine hydroxymethyltransferase-like domain KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 MB46_12250 cc99f49dcf9da6b2df8dfe0888d14c38 444 SUPERFAMILY SSF53383 24 438 1.18E-166 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MB46_12250 cc99f49dcf9da6b2df8dfe0888d14c38 444 Gene3D G3DSA:3.40.640.10 55 306 1.1E-173 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MB46_12250 cc99f49dcf9da6b2df8dfe0888d14c38 444 Gene3D G3DSA:3.90.1150.10 29 413 1.1E-173 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MB46_12250 cc99f49dcf9da6b2df8dfe0888d14c38 444 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 25 438 49.741 T 14-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 MB46_13195 ca644e098da3844c4c987145264e4c07 284 Gene3D G3DSA:1.10.3720.10 9 272 8.9E-54 T 14-10-2018 IPR035906 MetI-like superfamily MB46_13195 ca644e098da3844c4c987145264e4c07 284 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 100 276 7.5E-22 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_13195 ca644e098da3844c4c987145264e4c07 284 SUPERFAMILY SSF161098 13 284 5.98E-62 T 14-10-2018 IPR035906 MetI-like superfamily MB46_18580 0ac77f2742e63949b07e2bb680dfc792 374 Pfam PF14022 Protein of unknown function (DUF4238) 42 321 1.0E-32 T 14-10-2018 IPR025332 Protein of unknown function DUF4238 MB46_04045 cf10332c783d719ab64f52809e4a65b6 212 Pfam PF04402 Protein of unknown function (DUF541) 8 209 2.1E-37 T 14-10-2018 IPR007497 Protein of unknown function DUF541 MB46_04045 cf10332c783d719ab64f52809e4a65b6 212 Gene3D G3DSA:3.30.110.170 10 209 5.6E-47 T 14-10-2018 MB46_04045 cf10332c783d719ab64f52809e4a65b6 212 Gene3D G3DSA:3.30.70.2970 20 129 5.6E-47 T 14-10-2018 MB46_06805 ad0baee4d607a87bbe2601bf115a816b 78 Pfam PF00239 Resolvase, N terminal domain 11 47 2.2E-5 T 14-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 MB46_06805 ad0baee4d607a87bbe2601bf115a816b 78 Gene3D G3DSA:3.40.50.1390 4 51 5.6E-6 T 14-10-2018 MB46_06805 ad0baee4d607a87bbe2601bf115a816b 78 SUPERFAMILY SSF53041 10 77 2.22E-9 T 14-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 MB46_13800 c2903653b8cb1a4c05360766efacfb07 221 SUPERFAMILY SSF51735 1 210 4.45E-33 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_13800 c2903653b8cb1a4c05360766efacfb07 221 Gene3D G3DSA:3.40.50.720 3 221 5.4E-40 T 14-10-2018 MB46_13800 c2903653b8cb1a4c05360766efacfb07 221 Pfam PF13460 NAD(P)H-binding 8 199 3.2E-40 T 14-10-2018 IPR016040 NAD(P)-binding domain MB46_17885 eac332a1608b19ace82ec505a0c4c792 80 Pfam PF08818 Domain of unknown function (DU1801) 18 68 1.2E-6 T 14-10-2018 IPR014922 Domain of unknown function DUF1801 MB46_17885 eac332a1608b19ace82ec505a0c4c792 80 SUPERFAMILY SSF159888 2 70 6.41E-9 T 14-10-2018 MB46_08550 89dde5e1239c982e4cc523a36658939c 196 Pfam PF03652 Holliday junction resolvase 10 147 1.1E-36 T 14-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 MB46_08550 89dde5e1239c982e4cc523a36658939c 196 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 12 146 1.6E-25 T 14-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 MB46_08550 89dde5e1239c982e4cc523a36658939c 196 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 9 150 19.743 T 14-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 MB46_08550 89dde5e1239c982e4cc523a36658939c 196 SUPERFAMILY SSF53098 10 149 1.4E-30 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily MB46_08550 89dde5e1239c982e4cc523a36658939c 196 SMART SM00732 9 115 5.8E-18 T 14-10-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 MB46_08550 89dde5e1239c982e4cc523a36658939c 196 Gene3D G3DSA:3.30.420.140 10 158 3.3E-41 T 14-10-2018 IPR037027 YqgF/RNase H-like domain superfamily GO:0006139 MB46_06430 1f3b56c53b3d0d353b2d484a94df7e59 671 Pfam PF08310 LGFP repeat 126 178 1.9E-10 T 14-10-2018 IPR013207 LGFP MB46_06430 1f3b56c53b3d0d353b2d484a94df7e59 671 Pfam PF08310 LGFP repeat 284 336 5.8E-8 T 14-10-2018 IPR013207 LGFP MB46_06430 1f3b56c53b3d0d353b2d484a94df7e59 671 Pfam PF08310 LGFP repeat 180 230 1.1E-12 T 14-10-2018 IPR013207 LGFP MB46_06430 1f3b56c53b3d0d353b2d484a94df7e59 671 Pfam PF08310 LGFP repeat 80 124 6.0E-10 T 14-10-2018 IPR013207 LGFP MB46_06430 1f3b56c53b3d0d353b2d484a94df7e59 671 Pfam PF08310 LGFP repeat 232 281 1.4E-9 T 14-10-2018 IPR013207 LGFP MB46_06430 1f3b56c53b3d0d353b2d484a94df7e59 671 SUPERFAMILY SSF52266 425 606 5.07E-16 T 14-10-2018 MB46_06430 1f3b56c53b3d0d353b2d484a94df7e59 671 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 433 591 8.6E-14 T 14-10-2018 IPR013830 SGNH hydrolase-type esterase domain MB46_06430 1f3b56c53b3d0d353b2d484a94df7e59 671 Gene3D G3DSA:3.40.50.1110 406 610 1.4E-15 T 14-10-2018 IPR036514 SGNH hydrolase superfamily MB46_17785 b97674ec56d14e909cd7620cc8a1d1ca 569 Pfam PF05140 ResB-like family 42 525 1.3E-123 T 14-10-2018 IPR007816 ResB-like domain MB46_06490 979e27751522b2939297398e40c13d38 204 Pfam PF03737 Aldolase/RraA 30 164 3.0E-33 T 14-10-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein MB46_06490 979e27751522b2939297398e40c13d38 204 Gene3D G3DSA:3.50.30.100 1 186 2.0E-44 T 14-10-2018 MB46_06490 979e27751522b2939297398e40c13d38 204 SUPERFAMILY SSF89562 11 171 7.59E-39 T 14-10-2018 IPR036704 Ribonuclease E inhibitor RraA/RraA-like superfamily MB46_12165 29eadf20b11c7bfde27900686d42aa61 120 Gene3D G3DSA:3.10.180.10 2 120 1.8E-29 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MB46_12165 29eadf20b11c7bfde27900686d42aa61 120 SUPERFAMILY SSF54593 1 119 4.03E-18 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MB46_01985 b8e8c98f42aaca9a6d152c85dfc24418 216 Gene3D G3DSA:1.10.287.1080 1 125 9.9E-37 T 14-10-2018 MB46_01985 b8e8c98f42aaca9a6d152c85dfc24418 216 Gene3D G3DSA:1.10.287.1080 137 216 3.6E-13 T 14-10-2018 MB46_01985 b8e8c98f42aaca9a6d152c85dfc24418 216 SUPERFAMILY SSF101386 3 95 5.98E-18 T 14-10-2018 MB46_01985 b8e8c98f42aaca9a6d152c85dfc24418 216 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 22 94 1.8E-24 T 14-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core MB46_06845 5b4b4def064c6e409c243170cc98f14e 124 SUPERFAMILY SSF46785 16 120 9.89E-31 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_06845 5b4b4def064c6e409c243170cc98f14e 124 Pfam PF01638 HxlR-like helix-turn-helix 32 119 3.9E-28 T 14-10-2018 IPR002577 Helix-turn-helix, HxlR type MB46_06845 5b4b4def064c6e409c243170cc98f14e 124 Gene3D G3DSA:1.10.10.10 12 124 2.4E-38 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_18165 f6c7ccffacfa199a993bc16597a6cc1a 217 Pfam PF00392 Bacterial regulatory proteins, gntR family 16 77 1.3E-18 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MB46_18165 f6c7ccffacfa199a993bc16597a6cc1a 217 Pfam PF07729 FCD domain 90 206 1.5E-14 T 14-10-2018 IPR011711 GntR, C-terminal MB46_18165 f6c7ccffacfa199a993bc16597a6cc1a 217 SUPERFAMILY SSF46785 15 100 2.65E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_18165 f6c7ccffacfa199a993bc16597a6cc1a 217 SUPERFAMILY SSF48008 95 207 3.14E-14 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MB46_18165 f6c7ccffacfa199a993bc16597a6cc1a 217 Gene3D G3DSA:1.20.120.530 85 209 5.1E-16 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MB46_18165 f6c7ccffacfa199a993bc16597a6cc1a 217 SMART SM00345 19 77 6.4E-19 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MB46_18165 f6c7ccffacfa199a993bc16597a6cc1a 217 SMART SM00895 87 210 8.2E-8 T 14-10-2018 IPR011711 GntR, C-terminal MB46_18165 f6c7ccffacfa199a993bc16597a6cc1a 217 Gene3D G3DSA:1.10.10.10 12 78 4.8E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_02375 4e5a5ea7c7a0be17f09f77ef2bfc39e9 368 TIGRFAM TIGR01906 integ_TIGR01906: integral membrane protein TIGR01906 143 344 8.9E-27 T 14-10-2018 IPR010178 Integral membrane protein 1906 MB46_02375 4e5a5ea7c7a0be17f09f77ef2bfc39e9 368 Pfam PF07314 Protein of unknown function (DUF1461) 145 325 1.2E-28 T 14-10-2018 IPR010178 Integral membrane protein 1906 MB46_06290 ffe99d7a6ff186ac7796120d4577fcff 547 SUPERFAMILY SSF51905 2 210 6.73E-7 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_06290 ffe99d7a6ff186ac7796120d4577fcff 547 Pfam PF13454 FAD-NAD(P)-binding 5 154 1.0E-23 T 14-10-2018 IPR038732 FAD-dependent urate hydroxylase HpyO, FAD/NAD(P)-binding domain MB46_06290 ffe99d7a6ff186ac7796120d4577fcff 547 Gene3D G3DSA:3.50.50.60 1 171 2.8E-6 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_11245 ef644c44e367d048854e05486278e3ce 372 Pfam PF03193 RsgA GTPase 100 292 4.0E-36 T 14-10-2018 IPR010914 RsgA GTPase domain GO:0003924|GO:0005525 MB46_11245 ef644c44e367d048854e05486278e3ce 372 Gene3D G3DSA:3.40.50.300 103 292 1.8E-37 T 14-10-2018 MB46_11245 ef644c44e367d048854e05486278e3ce 372 SUPERFAMILY SSF52540 118 309 8.44E-32 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_11245 ef644c44e367d048854e05486278e3ce 372 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 77 329 3.1E-31 T 14-10-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 MB46_12970 3d7efbd2024eae51b5f9542199d3c90c 161 Pfam PF12823 Domain of unknown function (DUF3817) 27 145 4.2E-26 T 14-10-2018 IPR023845 Domain of unknown function DUF3817, transmembrane MB46_12970 3d7efbd2024eae51b5f9542199d3c90c 161 TIGRFAM TIGR03954 integ_memb_HG: integral membrane protein 91 143 4.1E-14 T 14-10-2018 IPR023845 Domain of unknown function DUF3817, transmembrane MB46_15000 f2c4daace4ee4036724ddeb948794a07 428 SUPERFAMILY SSF53850 21 423 1.33E-74 T 14-10-2018 MB46_15000 f2c4daace4ee4036724ddeb948794a07 428 Gene3D G3DSA:3.40.190.10 149 412 1.3E-86 T 14-10-2018 MB46_15000 f2c4daace4ee4036724ddeb948794a07 428 Gene3D G3DSA:3.40.190.10 48 376 1.3E-86 T 14-10-2018 MB46_15000 f2c4daace4ee4036724ddeb948794a07 428 Pfam PF01547 Bacterial extracellular solute-binding protein 44 335 3.3E-38 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein MB46_15565 756412055a33e40fe668d52391855d9c 281 Gene3D G3DSA:3.30.1240.10 109 207 2.3E-49 T 14-10-2018 MB46_15565 756412055a33e40fe668d52391855d9c 281 Pfam PF08282 haloacid dehalogenase-like hydrolase 24 274 2.1E-42 T 14-10-2018 MB46_15565 756412055a33e40fe668d52391855d9c 281 ProSitePatterns PS01229 Hypothetical cof family signature 2. 231 253 - T 14-10-2018 MB46_15565 756412055a33e40fe668d52391855d9c 281 Gene3D G3DSA:3.40.50.1000 23 273 2.3E-49 T 14-10-2018 IPR023214 HAD superfamily MB46_15565 756412055a33e40fe668d52391855d9c 281 SUPERFAMILY SSF56784 19 280 2.58E-50 T 14-10-2018 IPR036412 HAD-like superfamily MB46_01595 4718276ce30bd7fb7b2e4636f3bcaf35 207 Pfam PF09335 SNARE associated Golgi protein 33 157 6.7E-14 T 14-10-2018 IPR032816 SNARE associated Golgi protein MB46_15625 c0507f4ea407569bf891769c8f63464e 439 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 30 406 1.5E-91 T 14-10-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 MB46_15625 c0507f4ea407569bf891769c8f63464e 439 Pfam PF00860 Permease family 34 388 6.8E-76 T 14-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 MB46_07115 787f3a8af5eb1a4a64f8331be0c11aba 119 Pfam PF04237 YjbR 18 109 1.4E-17 T 14-10-2018 IPR007351 Uncharacterised protein YjbR MB46_07115 787f3a8af5eb1a4a64f8331be0c11aba 119 SUPERFAMILY SSF142906 11 117 2.09E-21 T 14-10-2018 IPR038056 YjbR-like superfamily MB46_07115 787f3a8af5eb1a4a64f8331be0c11aba 119 Gene3D G3DSA:3.90.1150.30 3 119 1.6E-23 T 14-10-2018 IPR038056 YjbR-like superfamily MB46_08230 acb1806359d019dbafbd52121b82f660 262 Pfam PF03799 Cell division protein FtsQ 129 232 1.8E-9 T 14-10-2018 IPR005548 Cell division protein FtsQ/DivIB MB46_00340 92cc9444c3c61728240981bf4fa7a39b 549 Gene3D G3DSA:3.90.400.10 117 194 4.2E-134 T 14-10-2018 MB46_00340 92cc9444c3c61728240981bf4fa7a39b 549 Gene3D G3DSA:3.20.20.80 17 470 4.2E-134 T 14-10-2018 MB46_00340 92cc9444c3c61728240981bf4fa7a39b 549 SMART SM00642 25 407 2.5E-102 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MB46_00340 92cc9444c3c61728240981bf4fa7a39b 549 Pfam PF00128 Alpha amylase, catalytic domain 40 384 2.6E-74 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MB46_00340 92cc9444c3c61728240981bf4fa7a39b 549 SUPERFAMILY SSF51445 16 472 9.51E-114 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily MB46_10445 a2f8f934dcbaedf4a3a0a4025cd04009 292 Gene3D G3DSA:2.70.70.10 1 160 5.2E-33 T 14-10-2018 IPR011055 Duplicated hybrid motif MB46_10445 a2f8f934dcbaedf4a3a0a4025cd04009 292 SUPERFAMILY SSF51261 6 149 5.75E-27 T 14-10-2018 IPR011055 Duplicated hybrid motif MB46_10445 a2f8f934dcbaedf4a3a0a4025cd04009 292 Pfam PF01551 Peptidase family M23 30 132 2.2E-20 T 14-10-2018 IPR016047 Peptidase M23 MB46_14145 8278c39a71c613b7615b55c67aaffcb3 454 Gene3D G3DSA:3.90.1150.10 22 447 1.2E-167 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MB46_14145 8278c39a71c613b7615b55c67aaffcb3 454 Pfam PF00202 Aminotransferase class-III 44 451 1.4E-125 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MB46_14145 8278c39a71c613b7615b55c67aaffcb3 454 TIGRFAM TIGR00700 GABAtrnsam: 4-aminobutyrate transaminase 31 452 9.5E-178 T 14-10-2018 IPR004632 4-aminobutyrate aminotransferase, bacterial GO:0003867|GO:0009448 MB46_14145 8278c39a71c613b7615b55c67aaffcb3 454 PIRSF PIRSF000521 2 150 3.8E-6 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MB46_14145 8278c39a71c613b7615b55c67aaffcb3 454 PIRSF PIRSF000521 146 454 8.4E-36 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MB46_14145 8278c39a71c613b7615b55c67aaffcb3 454 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 260 297 - T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MB46_14145 8278c39a71c613b7615b55c67aaffcb3 454 SUPERFAMILY SSF53383 40 452 4.87E-122 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MB46_14145 8278c39a71c613b7615b55c67aaffcb3 454 Gene3D G3DSA:3.40.640.10 80 343 1.2E-167 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MB46_11280 7956ed2dcbfecea1426c38353178a883 547 SUPERFAMILY SSF56801 39 543 1.96E-130 T 14-10-2018 MB46_11280 7956ed2dcbfecea1426c38353178a883 547 Gene3D G3DSA:3.30.300.310 441 545 8.0E-29 T 14-10-2018 MB46_11280 7956ed2dcbfecea1426c38353178a883 547 Gene3D G3DSA:3.40.50.12780 16 440 6.4E-95 T 14-10-2018 MB46_11280 7956ed2dcbfecea1426c38353178a883 547 Pfam PF13193 AMP-binding enzyme C-terminal domain 454 531 1.1E-23 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain MB46_11280 7956ed2dcbfecea1426c38353178a883 547 Pfam PF00501 AMP-binding enzyme 27 444 4.1E-77 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 MB46_17180 6e5281fd9b6f39759c84e60381a87e37 541 Pfam PF13088 BNR repeat-like domain 52 331 5.0E-21 T 14-10-2018 IPR011040 Sialidase KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 MB46_17180 6e5281fd9b6f39759c84e60381a87e37 541 Gene3D G3DSA:2.120.10.10 3 356 5.2E-98 T 14-10-2018 MB46_17180 6e5281fd9b6f39759c84e60381a87e37 541 SUPERFAMILY SSF50939 9 353 7.85E-81 T 14-10-2018 IPR036278 Sialidase superfamily KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 MB46_05650 6543b8f5f8f0818da9080d15fe4be372 261 SUPERFAMILY SSF161098 61 247 1.22E-33 T 14-10-2018 IPR035906 MetI-like superfamily MB46_05650 6543b8f5f8f0818da9080d15fe4be372 261 Gene3D G3DSA:1.10.3720.10 61 255 2.5E-25 T 14-10-2018 IPR035906 MetI-like superfamily MB46_05650 6543b8f5f8f0818da9080d15fe4be372 261 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 85 254 2.6E-23 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_10640 4de73de6bf33d076e723775f1725697c 273 SUPERFAMILY SSF53474 22 261 9.55E-33 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_10640 4de73de6bf33d076e723775f1725697c 273 Pfam PF00561 alpha/beta hydrolase fold 37 169 1.1E-19 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MB46_10640 4de73de6bf33d076e723775f1725697c 273 Gene3D G3DSA:3.40.50.1820 3 270 4.5E-32 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_14850 b7f6a566cd53510bd52c4799cb819518 463 Gene3D G3DSA:3.20.20.140 6 441 3.2E-139 T 14-10-2018 MB46_14850 b7f6a566cd53510bd52c4799cb819518 463 TIGRFAM TIGR03178 allantoinase: allantoinase 15 444 5.4E-168 T 14-10-2018 IPR017593 Allantoinase GO:0000256|GO:0004038|GO:0008270|GO:0050897 KEGG: 00230+3.5.2.5|MetaCyc: PWY-5697|MetaCyc: PWY-5698 MB46_14850 b7f6a566cd53510bd52c4799cb819518 463 SUPERFAMILY SSF51338 14 441 4.32E-19 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 MB46_14850 b7f6a566cd53510bd52c4799cb819518 463 ProSitePatterns PS00482 Dihydroorotase signature 1. 71 79 - T 14-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MB46_14850 b7f6a566cd53510bd52c4799cb819518 463 Pfam PF01979 Amidohydrolase family 64 440 5.0E-37 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 MB46_14850 b7f6a566cd53510bd52c4799cb819518 463 SUPERFAMILY SSF51556 68 386 3.89E-100 T 14-10-2018 IPR032466 Metal-dependent hydrolase MB46_17100 bd378711acd89042ce96a2e5d51457c2 431 SUPERFAMILY SSF51445 7 331 1.24E-28 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily MB46_17100 bd378711acd89042ce96a2e5d51457c2 431 Gene3D G3DSA:3.20.20.80 7 311 1.3E-23 T 14-10-2018 MB46_15780 40c518a8113216554e89bc5e0c60edef 193 Gene3D G3DSA:2.60.60.30 20 187 2.7E-73 T 14-10-2018 MB46_15780 40c518a8113216554e89bc5e0c60edef 193 Pfam PF02342 TerD domain 4 188 2.6E-79 T 14-10-2018 IPR003325 TerD domain MB46_06710 0321307b12a1efbbca9443bfcffdd666 547 Pfam PF03109 ABC1 family 104 222 2.9E-34 T 14-10-2018 IPR004147 UbiB domain MB46_06710 0321307b12a1efbbca9443bfcffdd666 547 SUPERFAMILY SSF56112 87 418 1.88E-27 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily MB46_01660 136fad02dbb3782f923060d881de29f0 437 Pfam PF07687 Peptidase dimerisation domain 194 323 7.5E-11 T 14-10-2018 IPR011650 Peptidase M20, dimerisation domain MB46_01660 136fad02dbb3782f923060d881de29f0 437 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 72 81 - T 14-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 MB46_01660 136fad02dbb3782f923060d881de29f0 437 Pfam PF01546 Peptidase family M20/M25/M40 73 434 1.0E-34 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 MB46_01660 136fad02dbb3782f923060d881de29f0 437 SUPERFAMILY SSF55031 197 326 5.23E-9 T 14-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain MB46_01660 136fad02dbb3782f923060d881de29f0 437 SUPERFAMILY SSF53187 2 435 4.37E-52 T 14-10-2018 MB46_01660 136fad02dbb3782f923060d881de29f0 437 Gene3D G3DSA:3.40.630.10 1 200 1.1E-47 T 14-10-2018 MB46_05630 14d1f12fc5ae859888dfb1e72c70a8e0 83 SUPERFAMILY SSF47789 26 77 1.2E-6 T 14-10-2018 MB46_05630 14d1f12fc5ae859888dfb1e72c70a8e0 83 Gene3D G3DSA:1.10.150.20 25 78 4.2E-7 T 14-10-2018 MB46_16625 16b6488b12c5335ccb05da3489ab67dc 473 Pfam PF09852 Predicted membrane protein (DUF2079) 57 438 5.7E-59 T 14-10-2018 IPR018650 Sulfolobus virus STSV1, Orf64 MB46_15250 d55fe2700b9d3bdb7ddc451b10514da1 689 SUPERFAMILY SSF63829 361 611 2.09E-7 T 14-10-2018 MB46_15250 d55fe2700b9d3bdb7ddc451b10514da1 689 Pfam PF05787 Bacterial protein of unknown function (DUF839) 101 648 2.8E-162 T 14-10-2018 IPR008557 Protein of unknown function DUF839 MB46_11465 47f99e5b8a66b89af5defc311180d5c9 390 Gene3D G3DSA:3.40.50.2000 203 355 2.8E-32 T 14-10-2018 MB46_11465 47f99e5b8a66b89af5defc311180d5c9 390 SUPERFAMILY SSF53756 21 384 2.34E-55 T 14-10-2018 MB46_11465 47f99e5b8a66b89af5defc311180d5c9 390 Pfam PF13439 Glycosyltransferase Family 4 23 191 2.4E-15 T 14-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 MB46_11465 47f99e5b8a66b89af5defc311180d5c9 390 Pfam PF00534 Glycosyl transferases group 1 203 345 1.3E-27 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 MB46_11465 47f99e5b8a66b89af5defc311180d5c9 390 Gene3D G3DSA:3.40.50.2000 19 202 3.1E-16 T 14-10-2018 MB46_14955 95d1699bc81d60f101bb7a0fc4abfd4f 169 SUPERFAMILY SSF55729 2 164 4.18E-36 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase MB46_14955 95d1699bc81d60f101bb7a0fc4abfd4f 169 Pfam PF13302 Acetyltransferase (GNAT) domain 2 139 1.3E-14 T 14-10-2018 IPR000182 GNAT domain MB46_14955 95d1699bc81d60f101bb7a0fc4abfd4f 169 Gene3D G3DSA:3.40.630.30 1 166 4.2E-38 T 14-10-2018 MB46_18385 329718028c39a6d34e90130620dcfa1c 179 Pfam PF16262 Domain of unknown function (DUF4916) 9 176 1.0E-80 T 14-10-2018 IPR032582 Protein of unknown function DUF4916 MB46_18385 329718028c39a6d34e90130620dcfa1c 179 Gene3D G3DSA:3.90.79.10 22 178 1.1E-42 T 14-10-2018 MB46_18385 329718028c39a6d34e90130620dcfa1c 179 SUPERFAMILY SSF55811 47 153 1.72E-6 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 MB46_17325 a5e62bdb4eeca7013a1b147fed834097 314 SUPERFAMILY SSF55811 30 229 3.17E-10 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 MB46_17325 a5e62bdb4eeca7013a1b147fed834097 314 Gene3D G3DSA:3.90.79.10 38 268 6.3E-41 T 14-10-2018 MB46_16945 6d74e3b98c729ac9456aae9c91370e2d 542 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 325 344 3.5E-15 T 14-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MB46_16945 6d74e3b98c729ac9456aae9c91370e2d 542 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 239 263 3.5E-15 T 14-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MB46_16945 6d74e3b98c729ac9456aae9c91370e2d 542 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 138 157 3.5E-15 T 14-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MB46_16945 6d74e3b98c729ac9456aae9c91370e2d 542 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 168 192 3.5E-15 T 14-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MB46_16945 6d74e3b98c729ac9456aae9c91370e2d 542 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 377 403 3.5E-15 T 14-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MB46_16945 6d74e3b98c729ac9456aae9c91370e2d 542 Pfam PF00361 Proton-conducting membrane transporter 132 417 3.3E-65 T 14-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MB46_16300 4d652dab14a287bb55cbeb6788e4aa64 202 Pfam PF00436 Single-strand binding protein family 6 106 9.7E-31 T 14-10-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 MB46_16300 4d652dab14a287bb55cbeb6788e4aa64 202 Gene3D G3DSA:2.40.50.140 1 120 6.1E-43 T 14-10-2018 MB46_16300 4d652dab14a287bb55cbeb6788e4aa64 202 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 5 166 1.4E-32 T 14-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 MB46_16300 4d652dab14a287bb55cbeb6788e4aa64 202 Hamap MF_00984 Single-stranded DNA-binding protein. 4 113 31.771 T 14-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 MB46_16300 4d652dab14a287bb55cbeb6788e4aa64 202 SUPERFAMILY SSF50249 6 202 8.81E-43 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold MB46_10045 b2e74b7af64fe4f7b08787d4571f0031 203 Gene3D G3DSA:1.10.10.60 6 58 1.7E-9 T 14-10-2018 MB46_10045 b2e74b7af64fe4f7b08787d4571f0031 203 SUPERFAMILY SSF48498 77 197 1.19E-22 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily MB46_10045 b2e74b7af64fe4f7b08787d4571f0031 203 Gene3D G3DSA:1.10.357.10 61 197 1.2E-31 T 14-10-2018 MB46_10045 b2e74b7af64fe4f7b08787d4571f0031 203 Pfam PF16859 Bacterial transcriptional repressor C-terminal 77 187 4.3E-28 T 14-10-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MB46_15745 dd490f69cac3fe773875c471441c29aa 265 Pfam PF02754 Cysteine-rich domain 140 224 6.5E-14 T 14-10-2018 IPR004017 Cysteine-rich domain MB46_15745 dd490f69cac3fe773875c471441c29aa 265 Pfam PF02754 Cysteine-rich domain 3 85 8.0E-16 T 14-10-2018 IPR004017 Cysteine-rich domain MB46_16645 2eea99aeafdf8664d578f68b34af0088 152 Pfam PF13279 Thioesterase-like superfamily 10 124 1.4E-9 T 14-10-2018 MB46_16645 2eea99aeafdf8664d578f68b34af0088 152 SUPERFAMILY SSF54637 5 141 3.73E-19 T 14-10-2018 IPR029069 HotDog domain superfamily MB46_16645 2eea99aeafdf8664d578f68b34af0088 152 Gene3D G3DSA:3.10.129.10 2 144 7.0E-26 T 14-10-2018 MB46_04025 6c6fdcccf3cc890c0e82937f06e439ab 141 Gene3D G3DSA:3.90.79.10 2 139 3.0E-26 T 14-10-2018 MB46_04025 6c6fdcccf3cc890c0e82937f06e439ab 141 ProSitePatterns PS00893 Nudix box signature. 42 63 - T 14-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 MB46_04025 6c6fdcccf3cc890c0e82937f06e439ab 141 Pfam PF00293 NUDIX domain 18 114 1.6E-14 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MB46_04025 6c6fdcccf3cc890c0e82937f06e439ab 141 SUPERFAMILY SSF55811 7 138 7.58E-23 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 MB46_04025 6c6fdcccf3cc890c0e82937f06e439ab 141 PRINTS PR00502 NUDIX hydrolase family signature 51 66 3.0E-7 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 MB46_04025 6c6fdcccf3cc890c0e82937f06e439ab 141 PRINTS PR00502 NUDIX hydrolase family signature 37 51 3.0E-7 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 MB46_10985 e4485009519ccb7c7bd702f90bfbd399 609 Pfam PF01844 HNH endonuclease 530 572 3.2E-6 T 14-10-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 MB46_10985 e4485009519ccb7c7bd702f90bfbd399 609 Gene3D G3DSA:3.30.40.60 501 587 1.3E-5 T 14-10-2018 MB46_10985 e4485009519ccb7c7bd702f90bfbd399 609 SMART SM00507 518 568 1.7E-8 T 14-10-2018 IPR003615 HNH nuclease MB46_10985 e4485009519ccb7c7bd702f90bfbd399 609 Pfam PF02720 Domain of unknown function (DUF222) 200 477 3.3E-13 T 14-10-2018 IPR003870 Domain of unknown function DUF222 MB46_19685 93a17d742375b1c8448db8291e3ddb62 268 Pfam PF12695 Alpha/beta hydrolase family 91 253 5.4E-39 T 14-10-2018 IPR029059 Alpha/beta hydrolase fold-5 MB46_19685 93a17d742375b1c8448db8291e3ddb62 268 SUPERFAMILY SSF53474 80 240 4.82E-14 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_19685 93a17d742375b1c8448db8291e3ddb62 268 Gene3D G3DSA:3.40.50.1820 129 238 2.2E-12 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_19500 f8ace4c6b5a46d1f38809e8640f36e71 285 Pfam PF03457 Helicase associated domain 153 214 1.2E-14 T 14-10-2018 IPR005114 Helicase-associated MB46_19500 f8ace4c6b5a46d1f38809e8640f36e71 285 Pfam PF03457 Helicase associated domain 221 282 4.3E-14 T 14-10-2018 IPR005114 Helicase-associated MB46_19500 f8ace4c6b5a46d1f38809e8640f36e71 285 Pfam PF03457 Helicase associated domain 17 78 2.8E-14 T 14-10-2018 IPR005114 Helicase-associated MB46_19500 f8ace4c6b5a46d1f38809e8640f36e71 285 Pfam PF03457 Helicase associated domain 85 146 2.9E-17 T 14-10-2018 IPR005114 Helicase-associated MB46_17950 f0fb3d562390ae5002bc0eb348fac486 120 Gene3D G3DSA:1.10.10.810 2 115 2.7E-30 T 14-10-2018 MB46_17950 f0fb3d562390ae5002bc0eb348fac486 120 Pfam PF08818 Domain of unknown function (DU1801) 20 109 1.2E-13 T 14-10-2018 IPR014922 Domain of unknown function DUF1801 MB46_17950 f0fb3d562390ae5002bc0eb348fac486 120 SUPERFAMILY SSF159888 6 116 3.27E-31 T 14-10-2018 MB46_04850 776e355047722417545e0c2427e73926 674 Pfam PF02720 Domain of unknown function (DUF222) 100 297 6.3E-14 T 14-10-2018 IPR003870 Domain of unknown function DUF222 MB46_04850 776e355047722417545e0c2427e73926 674 Pfam PF01844 HNH endonuclease 515 554 7.3E-5 T 14-10-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 MB46_04850 776e355047722417545e0c2427e73926 674 SMART SM00507 499 551 3.9E-6 T 14-10-2018 IPR003615 HNH nuclease MB46_03855 7706af89ce1f8254646245e2f7799e31 160 SUPERFAMILY SSF54690 12 146 9.02E-37 T 14-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 MB46_03855 7706af89ce1f8254646245e2f7799e31 160 Gene3D G3DSA:3.90.1170.40 2 146 8.2E-47 T 14-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 MB46_03855 7706af89ce1f8254646245e2f7799e31 160 Pfam PF02391 MoaE protein 13 126 5.5E-32 T 14-10-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 MB46_11895 e815cd51d98c51faa41565e3c8bf1fef 287 Gene3D G3DSA:3.90.226.10 6 226 5.7E-58 T 14-10-2018 MB46_11895 e815cd51d98c51faa41565e3c8bf1fef 287 Gene3D G3DSA:1.10.12.10 227 280 2.4E-17 T 14-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal MB46_11895 e815cd51d98c51faa41565e3c8bf1fef 287 SUPERFAMILY SSF52096 19 274 6.94E-66 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MB46_11895 e815cd51d98c51faa41565e3c8bf1fef 287 Pfam PF00378 Enoyl-CoA hydratase/isomerase 24 268 3.8E-40 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 MB46_11895 e815cd51d98c51faa41565e3c8bf1fef 287 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 125 145 - T 14-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 MB46_06675 e3e05a2dfcb4715aa7f645fdf7c827a5 271 Pfam PF03618 Kinase/pyrophosphorylase 8 264 1.8E-66 T 14-10-2018 IPR005177 Bifunctional kinase-pyrophosphorylase GO:0005524|GO:0016772 MB46_06675 e3e05a2dfcb4715aa7f645fdf7c827a5 271 Hamap MF_01062 Phosphoenolpyruvate synthase regulatory protein [ppsR]. 5 271 66.483 T 14-10-2018 IPR026530 Phosphoenolpyruvate synthase regulatory protein MB46_10800 463c19a600b3c9a6fa30cb7b1c9b22c3 262 Gene3D G3DSA:3.40.50.1820 20 242 6.5E-27 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_10800 463c19a600b3c9a6fa30cb7b1c9b22c3 262 SUPERFAMILY SSF53474 24 238 3.24E-31 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_06420 3cc4b1419d474d54c95d07e87dd786d5 343 SUPERFAMILY SSF51430 1 320 5.5E-98 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily MB46_06420 3cc4b1419d474d54c95d07e87dd786d5 343 Gene3D G3DSA:3.20.20.100 1 341 3.3E-115 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily MB46_06420 3cc4b1419d474d54c95d07e87dd786d5 343 Pfam PF00248 Aldo/keto reductase family 18 317 1.7E-74 T 14-10-2018 IPR023210 NADP-dependent oxidoreductase domain MB46_14755 bd75215de106ea03cf472d7bf93787b4 499 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 350 370 - T 14-10-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 MB46_14755 bd75215de106ea03cf472d7bf93787b4 499 TIGRFAM TIGR03173 pbuX: xanthine permease 28 435 1.9E-150 T 14-10-2018 IPR017588 Uric acid permease UacT-like GO:0016021|GO:0022857|GO:0055085 MB46_14755 bd75215de106ea03cf472d7bf93787b4 499 Pfam PF00860 Permease family 25 401 1.9E-86 T 14-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 MB46_14755 bd75215de106ea03cf472d7bf93787b4 499 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 24 433 2.1E-100 T 14-10-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 MB46_06895 4ea75a89f58ac03d428535e15bb8996b 219 SUPERFAMILY SSF161098 10 209 8.76E-35 T 14-10-2018 IPR035906 MetI-like superfamily MB46_06895 4ea75a89f58ac03d428535e15bb8996b 219 Gene3D G3DSA:1.10.3720.10 5 219 1.8E-36 T 14-10-2018 IPR035906 MetI-like superfamily MB46_06895 4ea75a89f58ac03d428535e15bb8996b 219 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 37 216 2.1E-12 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_05620 4285ed8a364e6f7f769232fe409f0b86 157 PIRSF PIRSF010260 5 157 5.7E-37 T 14-10-2018 IPR014457 Uncharacterised conserved protein UCP010260 MB46_05620 4285ed8a364e6f7f769232fe409f0b86 157 Pfam PF09348 Domain of unknown function (DUF1990) 19 155 4.6E-35 T 14-10-2018 IPR018960 Domain of unknown function DUF1990 MB46_12200 500b8a854d8e4bec819e981e74cee937 148 SUPERFAMILY SSF55729 6 134 3.72E-20 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase MB46_12200 500b8a854d8e4bec819e981e74cee937 148 Pfam PF13508 Acetyltransferase (GNAT) domain 56 130 1.5E-7 T 14-10-2018 IPR000182 GNAT domain MB46_12200 500b8a854d8e4bec819e981e74cee937 148 Gene3D G3DSA:3.40.630.30 1 139 2.4E-18 T 14-10-2018 MB46_12680 3e3495607821e422b42b534a10d2f4f7 286 PIRSF PIRSF028756 21 284 5.6E-70 T 14-10-2018 IPR016898 Polyphosphate kinase 2 KEGG: 00190+2.7.4.1 MB46_12680 3e3495607821e422b42b534a10d2f4f7 286 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 38 261 2.4E-67 T 14-10-2018 IPR022488 Polyphosphate kinase-2-related MB46_12680 3e3495607821e422b42b534a10d2f4f7 286 SUPERFAMILY SSF52540 81 261 8.07E-15 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_12680 3e3495607821e422b42b534a10d2f4f7 286 Gene3D G3DSA:3.40.50.300 3 284 5.2E-110 T 14-10-2018 MB46_12680 3e3495607821e422b42b534a10d2f4f7 286 TIGRFAM TIGR03709 PPK2_rel_1: polyphosphate:nucleotide phosphotransferase, PPK2 family 18 277 4.0E-103 T 14-10-2018 IPR022300 Polyphosphate:nucleotide phosphotransferase, PPK2 GO:0006797|GO:0016776 KEGG: 00190+2.7.4.1 MB46_03350 9111ed2c697ca701c5c679dca2362284 230 Gene3D G3DSA:3.40.430.10 1 223 1.0E-53 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 MB46_03350 9111ed2c697ca701c5c679dca2362284 230 Pfam PF01872 RibD C-terminal domain 5 209 1.0E-34 T 14-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 MB46_03350 9111ed2c697ca701c5c679dca2362284 230 SUPERFAMILY SSF53597 3 222 1.44E-40 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 MB46_14515 21b249a6ea2535ba7853b1b753b03895 252 Pfam PF13398 Peptidase M50B-like 38 239 1.8E-42 T 14-10-2018 MB46_03680 0b1283fdfd56ae9c21bfe1f2992c4dfe 388 SUPERFAMILY SSF51717 48 219 1.65E-7 T 14-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MB46_03680 0b1283fdfd56ae9c21bfe1f2992c4dfe 388 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 19 361 6.4E-128 T 14-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 MB46_03680 0b1283fdfd56ae9c21bfe1f2992c4dfe 388 PIRSF PIRSF004640 13 374 2.0E-143 T 14-10-2018 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 MB46_03680 0b1283fdfd56ae9c21bfe1f2992c4dfe 388 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 17 368 33.306 T 14-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 MB46_03680 0b1283fdfd56ae9c21bfe1f2992c4dfe 388 Pfam PF04551 GcpE protein 22 362 7.4E-132 T 14-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 MB46_03680 0b1283fdfd56ae9c21bfe1f2992c4dfe 388 Gene3D G3DSA:3.20.20.20 14 272 9.2E-103 T 14-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MB46_03680 0b1283fdfd56ae9c21bfe1f2992c4dfe 388 Gene3D G3DSA:3.30.413.10 273 373 1.5E-36 T 14-10-2018 MB46_03680 0b1283fdfd56ae9c21bfe1f2992c4dfe 388 SUPERFAMILY SSF56014 277 364 3.1E-12 T 14-10-2018 MB46_17840 a7eb355818684e4a640374cf9d37fd01 274 SUPERFAMILY SSF161098 5 274 2.22E-65 T 14-10-2018 IPR035906 MetI-like superfamily MB46_17840 a7eb355818684e4a640374cf9d37fd01 274 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 89 266 1.2E-14 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_17840 a7eb355818684e4a640374cf9d37fd01 274 Gene3D G3DSA:1.10.3720.10 3 262 1.8E-58 T 14-10-2018 IPR035906 MetI-like superfamily MB46_15315 b0e4de516b86db50c00c0b1d7f612f47 330 Pfam PF01384 Phosphate transporter family 14 318 1.2E-57 T 14-10-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 MB46_05385 74c463c499bf9acc714ce940a18470ff 390 PIRSF PIRSF006404 11 388 1.2E-61 T 14-10-2018 IPR016483 Uncharacterised conserved protein UCP006404, peptidase M50/CBS MB46_04535 9e0add9d1604ce8b418e4327acadae4f 336 Gene3D G3DSA:3.40.50.1360 56 321 4.2E-86 T 14-10-2018 MB46_04535 9e0add9d1604ce8b418e4327acadae4f 336 Gene3D G3DSA:1.10.10.60 3 54 7.5E-17 T 14-10-2018 MB46_04535 9e0add9d1604ce8b418e4327acadae4f 336 SUPERFAMILY SSF46689 12 74 5.38E-5 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MB46_04535 9e0add9d1604ce8b418e4327acadae4f 336 Pfam PF04198 Putative sugar-binding domain 64 316 2.2E-59 T 14-10-2018 IPR007324 Sugar-binding domain, putative GO:0030246 MB46_04535 9e0add9d1604ce8b418e4327acadae4f 336 Pfam PF13384 Homeodomain-like domain 9 51 9.6E-6 T 14-10-2018 MB46_04535 9e0add9d1604ce8b418e4327acadae4f 336 SUPERFAMILY SSF100950 64 316 7.91E-63 T 14-10-2018 IPR037171 NagB/RpiA transferase-like MB46_16175 535043a61d14f05f61afcc3048312cd2 164 Gene3D G3DSA:3.40.630.30 23 155 4.6E-14 T 14-10-2018 MB46_16175 535043a61d14f05f61afcc3048312cd2 164 SUPERFAMILY SSF55729 24 158 1.27E-15 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase MB46_16175 535043a61d14f05f61afcc3048312cd2 164 Pfam PF00583 Acetyltransferase (GNAT) family 69 139 1.4E-6 T 14-10-2018 IPR000182 GNAT domain MB46_03025 e303f47b58607130af0db75ce05e87e8 125 SUPERFAMILY SSF55298 4 124 3.93E-29 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 MB46_03025 e303f47b58607130af0db75ce05e87e8 125 Pfam PF01042 Endoribonuclease L-PSP 16 123 3.7E-21 T 14-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 MB46_03025 e303f47b58607130af0db75ce05e87e8 125 Gene3D G3DSA:3.30.1330.40 1 125 6.0E-29 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 MB46_19540 0ae317568ab779f23d8c18b3464d5727 284 Pfam PF08279 HTH domain 229 280 2.3E-5 T 14-10-2018 IPR013196 Helix-turn-helix, type 11 MB46_19540 0ae317568ab779f23d8c18b3464d5727 284 Pfam PF10935 Protein of unknown function (DUF2637) 4 112 1.4E-11 T 14-10-2018 IPR021235 Protein of unknown function DUF2637 MB46_14030 c0da004238f3d3441092463e6f9dd367 258 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 149 251 1.4E-4 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MB46_14030 c0da004238f3d3441092463e6f9dd367 258 Gene3D G3DSA:3.10.180.10 7 127 5.0E-35 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MB46_14030 c0da004238f3d3441092463e6f9dd367 258 Gene3D G3DSA:3.10.180.10 136 258 3.6E-33 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MB46_14030 c0da004238f3d3441092463e6f9dd367 258 SUPERFAMILY SSF54593 11 170 3.36E-24 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MB46_14030 c0da004238f3d3441092463e6f9dd367 258 SUPERFAMILY SSF54593 143 256 1.48E-19 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MB46_14570 6ae29ed482e64f16c9ffabb9f9e87d5c 202 SUPERFAMILY SSF55729 6 183 2.57E-30 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase MB46_14570 6ae29ed482e64f16c9ffabb9f9e87d5c 202 Gene3D G3DSA:3.40.630.30 1 199 2.0E-39 T 14-10-2018 MB46_14570 6ae29ed482e64f16c9ffabb9f9e87d5c 202 Pfam PF13302 Acetyltransferase (GNAT) domain 14 158 2.1E-12 T 14-10-2018 IPR000182 GNAT domain MB46_14065 bd874d668c6244409210dfc04617d14c 426 Pfam PF05977 Transmembrane secretion effector 8 405 4.7E-33 T 14-10-2018 IPR010290 Transmembrane secretion effector MB46_14065 bd874d668c6244409210dfc04617d14c 426 Gene3D G3DSA:1.20.1250.20 12 413 2.2E-32 T 14-10-2018 MB46_14065 bd874d668c6244409210dfc04617d14c 426 SUPERFAMILY SSF103473 15 417 7.46E-38 T 14-10-2018 IPR036259 MFS transporter superfamily MB46_11475 bcfb3e552de9ba92514c7cd5af58d089 354 SUPERFAMILY SSF53756 1 352 1.61E-95 T 14-10-2018 MB46_11475 bcfb3e552de9ba92514c7cd5af58d089 354 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 1 349 4.9E-78 T 14-10-2018 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 MB46_11475 bcfb3e552de9ba92514c7cd5af58d089 354 Gene3D G3DSA:3.40.50.2000 188 331 1.2E-35 T 14-10-2018 MB46_11475 bcfb3e552de9ba92514c7cd5af58d089 354 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 25 348 6.6E-93 T 14-10-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 MB46_11475 bcfb3e552de9ba92514c7cd5af58d089 354 Gene3D G3DSA:3.40.50.2000 1 187 4.7E-70 T 14-10-2018 MB46_02630 dd387243866081fe6ca38709d3e26db8 309 Gene3D G3DSA:3.90.550.10 2 300 1.5E-84 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MB46_02630 dd387243866081fe6ca38709d3e26db8 309 SUPERFAMILY SSF53448 5 276 4.59E-60 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MB46_02630 dd387243866081fe6ca38709d3e26db8 309 Pfam PF00483 Nucleotidyl transferase 9 272 1.4E-26 T 14-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 MB46_02630 dd387243866081fe6ca38709d3e26db8 309 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 7 272 7.6E-104 T 14-10-2018 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343|MetaCyc: PWY-7817 MB46_06920 0cc1504017dcca4d7b56fc3db608149c 275 Gene3D G3DSA:3.10.180.10 1 128 2.9E-32 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MB46_06920 0cc1504017dcca4d7b56fc3db608149c 275 Gene3D G3DSA:3.10.180.10 129 270 5.3E-23 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MB46_06920 0cc1504017dcca4d7b56fc3db608149c 275 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 145 265 1.2E-4 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MB46_06920 0cc1504017dcca4d7b56fc3db608149c 275 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 19 120 5.1E-6 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MB46_06920 0cc1504017dcca4d7b56fc3db608149c 275 SUPERFAMILY SSF54593 19 251 2.66E-30 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MB46_11660 4b5f79279a235496f59e26f86b94f731 418 Pfam PF14258 Domain of unknown function (DUF4350) 68 141 6.4E-10 T 14-10-2018 IPR025646 Domain of unknown function DUF4350 MB46_00605 5913bbacba49e77ae1d6a50abdc34b0f 344 SUPERFAMILY SSF49899 36 250 2.63E-9 T 14-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily MB46_00605 5913bbacba49e77ae1d6a50abdc34b0f 344 Gene3D G3DSA:2.60.120.200 27 253 1.4E-11 T 14-10-2018 MB46_00605 5913bbacba49e77ae1d6a50abdc34b0f 344 Gene3D G3DSA:2.60.40.2700 259 339 8.4E-10 T 14-10-2018 MB46_05255 7b126828bf1045143bbb979490f1dc96 367 Gene3D G3DSA:3.30.390.50 13 106 6.6E-17 T 14-10-2018 MB46_05255 7b126828bf1045143bbb979490f1dc96 367 Gene3D G3DSA:3.30.930.10 121 366 1.2E-55 T 14-10-2018 MB46_05255 7b126828bf1045143bbb979490f1dc96 367 SUPERFAMILY SSF55681 109 364 3.91E-67 T 14-10-2018 MB46_05255 7b126828bf1045143bbb979490f1dc96 367 Pfam PF03099 Biotin/lipoate A/B protein ligase family 175 281 1.4E-7 T 14-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 MB46_16720 7203d488a6a48d4503089bf04315202f 163 Gene3D G3DSA:1.10.10.10 8 159 7.3E-30 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_16720 7203d488a6a48d4503089bf04315202f 163 Pfam PF12802 MarR family 45 99 1.1E-7 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MB46_16720 7203d488a6a48d4503089bf04315202f 163 SUPERFAMILY SSF46785 4 152 1.17E-22 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_16720 7203d488a6a48d4503089bf04315202f 163 SMART SM00347 34 137 5.9E-7 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MB46_17965 dba3a24956360ce22150d686d69bc6f3 141 SMART SM00347 25 125 4.5E-16 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MB46_17965 dba3a24956360ce22150d686d69bc6f3 141 Gene3D G3DSA:1.10.10.10 1 141 1.4E-32 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_17965 dba3a24956360ce22150d686d69bc6f3 141 ProSitePatterns PS01117 MarR-type HTH domain signature. 64 98 - T 14-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site MB46_17965 dba3a24956360ce22150d686d69bc6f3 141 SUPERFAMILY SSF46785 4 140 4.26E-28 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_17965 dba3a24956360ce22150d686d69bc6f3 141 Pfam PF12802 MarR family 31 89 5.2E-11 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MB46_12265 62d4537daab33e4517af265ff738e1ca 959 Hamap MF_00711 Glycine dehydrogenase (decarboxylating) [gcvP]. 4 953 24.038 T 14-10-2018 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 MB46_12265 62d4537daab33e4517af265ff738e1ca 959 SUPERFAMILY SSF53383 473 949 3.63E-89 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MB46_12265 62d4537daab33e4517af265ff738e1ca 959 Gene3D G3DSA:3.90.1150.10 761 898 4.3E-37 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MB46_12265 62d4537daab33e4517af265ff738e1ca 959 TIGRFAM TIGR00461 gcvP: glycine dehydrogenase 13 947 0.0 T 14-10-2018 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 MB46_12265 62d4537daab33e4517af265ff738e1ca 959 Gene3D G3DSA:3.40.640.10 93 354 2.4E-100 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MB46_12265 62d4537daab33e4517af265ff738e1ca 959 Gene3D G3DSA:3.40.640.10 518 748 9.9E-57 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MB46_12265 62d4537daab33e4517af265ff738e1ca 959 SUPERFAMILY SSF53383 20 440 2.11E-92 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MB46_12265 62d4537daab33e4517af265ff738e1ca 959 Pfam PF02347 Glycine cleavage system P-protein 12 440 3.4E-169 T 14-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 MB46_12265 62d4537daab33e4517af265ff738e1ca 959 Pfam PF02347 Glycine cleavage system P-protein 479 743 3.3E-10 T 14-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 MB46_02840 3ce7c6b9ed7deb5ccd979b16054990f6 832 SUPERFAMILY SSF82866 556 793 1.14E-28 T 14-10-2018 MB46_02840 3ce7c6b9ed7deb5ccd979b16054990f6 832 Gene3D G3DSA:1.20.1640.10 212 415 2.2E-7 T 14-10-2018 MB46_02840 3ce7c6b9ed7deb5ccd979b16054990f6 832 PRINTS PR00702 Acriflavin resistance protein family signature 377 400 1.4E-7 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MB46_02840 3ce7c6b9ed7deb5ccd979b16054990f6 832 PRINTS PR00702 Acriflavin resistance protein family signature 249 272 1.4E-7 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MB46_02840 3ce7c6b9ed7deb5ccd979b16054990f6 832 PRINTS PR00702 Acriflavin resistance protein family signature 302 326 1.4E-7 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MB46_02840 3ce7c6b9ed7deb5ccd979b16054990f6 832 Gene3D G3DSA:1.20.1640.10 605 792 3.6E-6 T 14-10-2018 MB46_02840 3ce7c6b9ed7deb5ccd979b16054990f6 832 Pfam PF03176 MMPL family 527 793 2.4E-34 T 14-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 MB46_02840 3ce7c6b9ed7deb5ccd979b16054990f6 832 Pfam PF03176 MMPL family 45 408 1.3E-48 T 14-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 MB46_02840 3ce7c6b9ed7deb5ccd979b16054990f6 832 SUPERFAMILY SSF82866 194 406 1.7E-26 T 14-10-2018 MB46_13780 71e5083595dab41d874a76a287238e69 296 SUPERFAMILY SSF161098 96 276 5.23E-32 T 14-10-2018 IPR035906 MetI-like superfamily MB46_13780 71e5083595dab41d874a76a287238e69 296 Gene3D G3DSA:1.10.3720.10 93 288 2.1E-25 T 14-10-2018 IPR035906 MetI-like superfamily MB46_13780 71e5083595dab41d874a76a287238e69 296 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 118 288 1.9E-22 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_02445 cc5b7d50c85c4f939532307ecfc476dc 462 Gene3D G3DSA:2.160.10.10 243 429 4.3E-50 T 14-10-2018 MB46_02445 cc5b7d50c85c4f939532307ecfc476dc 462 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 385 419 6.3E-6 T 14-10-2018 IPR001451 Hexapeptide repeat MB46_02445 cc5b7d50c85c4f939532307ecfc476dc 462 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 307 336 4.7E-5 T 14-10-2018 IPR001451 Hexapeptide repeat MB46_02445 cc5b7d50c85c4f939532307ecfc476dc 462 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 1 442 1.7E-151 T 14-10-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 MB46_02445 cc5b7d50c85c4f939532307ecfc476dc 462 Pfam PF00483 Nucleotidyl transferase 3 213 8.0E-14 T 14-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 MB46_02445 cc5b7d50c85c4f939532307ecfc476dc 462 SUPERFAMILY SSF53448 1 241 2.93E-44 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MB46_02445 cc5b7d50c85c4f939532307ecfc476dc 462 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 1 442 34.242 T 14-10-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 MB46_02445 cc5b7d50c85c4f939532307ecfc476dc 462 Gene3D G3DSA:3.90.550.10 1 242 4.4E-54 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MB46_02445 cc5b7d50c85c4f939532307ecfc476dc 462 SUPERFAMILY SSF51161 239 428 6.26E-39 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily MB46_13370 ec645e45ddf1cecd4c0339cea4d224b6 132 Gene3D G3DSA:3.30.1370.30 2 72 1.2E-25 T 14-10-2018 MB46_13370 ec645e45ddf1cecd4c0339cea4d224b6 132 ProSitePatterns PS00053 Ribosomal protein S8 signature. 102 119 - T 14-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MB46_13370 ec645e45ddf1cecd4c0339cea4d224b6 132 SUPERFAMILY SSF56047 3 132 4.84E-43 T 14-10-2018 IPR035987 Ribosomal protein S8 superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MB46_13370 ec645e45ddf1cecd4c0339cea4d224b6 132 Gene3D G3DSA:3.30.1490.10 75 132 5.8E-25 T 14-10-2018 MB46_13370 ec645e45ddf1cecd4c0339cea4d224b6 132 Pfam PF00410 Ribosomal protein S8 5 132 4.5E-49 T 14-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MB46_13370 ec645e45ddf1cecd4c0339cea4d224b6 132 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 132 30.419 T 14-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MB46_19490 4905de339789be6cac42b49d7f8505da 259 Pfam PF13614 AAA domain 5 179 7.1E-37 T 14-10-2018 IPR025669 AAA domain MB46_19490 4905de339789be6cac42b49d7f8505da 259 SUPERFAMILY SSF52540 4 249 6.65E-44 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_19490 4905de339789be6cac42b49d7f8505da 259 Gene3D G3DSA:3.40.50.300 2 255 9.1E-54 T 14-10-2018 MB46_19840 247f4c473b0d7b85f408685a7f8671fe 292 Gene3D G3DSA:3.90.25.10 154 283 8.7E-78 T 14-10-2018 MB46_19840 247f4c473b0d7b85f408685a7f8671fe 292 Gene3D G3DSA:3.40.50.720 8 276 8.7E-78 T 14-10-2018 MB46_19840 247f4c473b0d7b85f408685a7f8671fe 292 Pfam PF05368 NmrA-like family 9 236 1.3E-48 T 14-10-2018 IPR008030 NmrA-like domain Reactome: R-HSA-70635 MB46_19840 247f4c473b0d7b85f408685a7f8671fe 292 SUPERFAMILY SSF51735 6 273 2.26E-65 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_03660 50d76d901b19ef2a8a6deea244b22d2e 427 Gene3D G3DSA:3.20.20.70 53 425 1.9E-126 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MB46_03660 50d76d901b19ef2a8a6deea244b22d2e 427 ProSitePatterns PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. 317 323 - T 14-10-2018 IPR008259 FMN-dependent alpha-hydroxy acid dehydrogenase, active site GO:0016491|GO:0055114 Reactome: R-HSA-9033241 MB46_03660 50d76d901b19ef2a8a6deea244b22d2e 427 SUPERFAMILY SSF51395 54 422 4.27E-93 T 14-10-2018 MB46_03660 50d76d901b19ef2a8a6deea244b22d2e 427 Pfam PF01070 FMN-dependent dehydrogenase 62 423 1.1E-125 T 14-10-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 Reactome: R-HSA-9033241 MB46_03660 50d76d901b19ef2a8a6deea244b22d2e 427 PIRSF PIRSF000138 36 426 1.4E-126 T 14-10-2018 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 Reactome: R-HSA-9033241 MB46_05180 31885edda4435f44abd04ec98077570d 235 Gene3D G3DSA:3.40.50.300 12 233 4.3E-55 T 14-10-2018 MB46_05180 31885edda4435f44abd04ec98077570d 235 SMART SM00382 36 216 7.5E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_05180 31885edda4435f44abd04ec98077570d 235 Pfam PF00005 ABC transporter 32 171 1.9E-26 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_05180 31885edda4435f44abd04ec98077570d 235 SUPERFAMILY SSF52540 26 221 6.58E-51 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_06890 abed95f8ef9bd49a5a700e58d0b08946 396 Pfam PF00296 Luciferase-like monooxygenase 17 330 1.6E-58 T 14-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MB46_06890 abed95f8ef9bd49a5a700e58d0b08946 396 SUPERFAMILY SSF51679 15 361 3.53E-66 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 MB46_06890 abed95f8ef9bd49a5a700e58d0b08946 396 Gene3D G3DSA:3.20.20.30 5 366 3.0E-85 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 MB46_16930 32c51b439ce05a82796eef502cf81e20 441 SUPERFAMILY SSF103473 34 433 2.22E-36 T 14-10-2018 IPR036259 MFS transporter superfamily MB46_16930 32c51b439ce05a82796eef502cf81e20 441 Gene3D G3DSA:1.20.1250.20 28 433 4.9E-29 T 14-10-2018 MB46_16930 32c51b439ce05a82796eef502cf81e20 441 Pfam PF11700 Vacuole effluxer Atg22 like 58 433 8.1E-30 T 14-10-2018 IPR024671 Autophagy-related protein 22-like MB46_10680 b40ff81a4cd49af7b08ec2c8671be7f6 159 Pfam PF14340 Domain of unknown function (DUF4395) 11 139 7.7E-36 T 14-10-2018 IPR025508 Domain of unknown function DUF4395 MB46_09630 600c5f08e57fc5371d86986ff5959978 453 SUPERFAMILY SSF111352 2 399 2.48E-118 T 14-10-2018 MB46_09630 600c5f08e57fc5371d86986ff5959978 453 Gene3D G3DSA:1.10.3430.10 1 430 3.4E-140 T 14-10-2018 IPR029020 Ammonium/urea transporter MB46_09630 600c5f08e57fc5371d86986ff5959978 453 Pfam PF00909 Ammonium Transporter Family 7 418 6.5E-127 T 14-10-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 MB46_09630 600c5f08e57fc5371d86986ff5959978 453 TIGRFAM TIGR00836 amt: ammonium transporter 5 418 4.0E-137 T 14-10-2018 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 MB46_09630 600c5f08e57fc5371d86986ff5959978 453 ProSitePatterns PS01219 Ammonium transporters signature. 173 198 - T 14-10-2018 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 MB46_03760 a3954e5e374128f997a95be4c7583f00 145 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 1 110 9.4E-25 T 14-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 MB46_03760 a3954e5e374128f997a95be4c7583f00 145 ProSitePatterns PS01319 Ribosome-binding factor A signature. 75 96 - T 14-10-2018 IPR020053 Ribosome-binding factor A, conserved site GO:0006364 MB46_03760 a3954e5e374128f997a95be4c7583f00 145 SUPERFAMILY SSF89919 1 111 1.96E-29 T 14-10-2018 IPR023799 Ribosome-binding factor A domain superfamily MB46_03760 a3954e5e374128f997a95be4c7583f00 145 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 10 96 5.0E-36 T 14-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 MB46_03760 a3954e5e374128f997a95be4c7583f00 145 Pfam PF02033 Ribosome-binding factor A 6 109 3.9E-26 T 14-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 MB46_03760 a3954e5e374128f997a95be4c7583f00 145 Gene3D G3DSA:3.30.300.20 2 117 7.1E-28 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta MB46_03760 a3954e5e374128f997a95be4c7583f00 145 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 5 109 23.997 T 14-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 MB46_16910 0ab77af7b9c1ee1b2d7b54ee72925250 102 Pfam PF09851 Short C-terminal domain 75 98 1.0E-6 T 14-10-2018 IPR018649 SHOCT domain MB46_05185 94aed2770305a24519f883103370aa7a 192 PIRSF PIRSF016661 4 189 7.4E-38 T 14-10-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 MB46_05185 94aed2770305a24519f883103370aa7a 192 Gene3D G3DSA:1.10.1760.20 3 186 8.3E-48 T 14-10-2018 MB46_05185 94aed2770305a24519f883103370aa7a 192 Pfam PF02632 BioY family 40 180 1.5E-33 T 14-10-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 MB46_19875 7a6c7dfa8b59b91cc5c6c324f2935ca3 586 SUPERFAMILY SSF50969 268 479 1.73E-5 T 14-10-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like MB46_02355 b8fb1be246f4d6887427fa82fb5c190a 60 Pfam PF04964 Flp/Fap pilin component 12 55 2.9E-12 T 14-10-2018 IPR007047 Flp/Fap pilin component MB46_12935 04fc19752366b74d1bcc1ba41a51245c 300 SUPERFAMILY SSF53448 4 276 7.93E-60 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MB46_12935 04fc19752366b74d1bcc1ba41a51245c 300 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 7 272 4.5E-103 T 14-10-2018 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343|MetaCyc: PWY-7817 MB46_12935 04fc19752366b74d1bcc1ba41a51245c 300 Gene3D G3DSA:3.90.550.10 1 300 1.1E-84 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MB46_12935 04fc19752366b74d1bcc1ba41a51245c 300 Pfam PF00483 Nucleotidyl transferase 9 272 2.3E-26 T 14-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 MB46_19525 3124412acf0d13e6b849c68386393dbf 383 SUPERFAMILY SSF53474 125 377 2.59E-34 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_19525 3124412acf0d13e6b849c68386393dbf 383 Gene3D G3DSA:3.40.50.1820 127 382 3.1E-32 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_19525 3124412acf0d13e6b849c68386393dbf 383 Pfam PF12697 Alpha/beta hydrolase family 152 330 2.5E-8 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MB46_04735 0d8349f59ec5b9289520ee36d5d553b3 557 Gene3D G3DSA:1.20.810.10 5 467 3.6E-95 T 14-10-2018 IPR027387 Cytochrome b/b6-like domain superfamily Reactome: R-HSA-611105 MB46_04735 0d8349f59ec5b9289520ee36d5d553b3 557 Pfam PF13631 Cytochrome b(N-terminal)/b6/petB 121 294 1.5E-60 T 14-10-2018 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 MB46_04735 0d8349f59ec5b9289520ee36d5d553b3 557 SUPERFAMILY SSF81342 20 300 6.75E-64 T 14-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 MB46_07855 35d7f93562a795ccbe98f520ea6d678b 150 Gene3D G3DSA:2.102.10.10 46 149 1.3E-24 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 MB46_07855 35d7f93562a795ccbe98f520ea6d678b 150 Pfam PF00355 Rieske [2Fe-2S] domain 54 137 5.9E-17 T 14-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MB46_07855 35d7f93562a795ccbe98f520ea6d678b 150 PRINTS PR00162 Rieske 2Fe-2S subunit signature 109 121 2.0E-7 T 14-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 MB46_07855 35d7f93562a795ccbe98f520ea6d678b 150 PRINTS PR00162 Rieske 2Fe-2S subunit signature 122 134 2.0E-7 T 14-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 MB46_07855 35d7f93562a795ccbe98f520ea6d678b 150 PRINTS PR00162 Rieske 2Fe-2S subunit signature 90 101 2.0E-7 T 14-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 MB46_07855 35d7f93562a795ccbe98f520ea6d678b 150 SUPERFAMILY SSF50022 49 148 6.55E-28 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 MB46_08110 6bff2eb881b7995c41eb5cce54dc63f6 182 SUPERFAMILY SSF55729 45 168 5.41E-14 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase MB46_08110 6bff2eb881b7995c41eb5cce54dc63f6 182 Pfam PF00583 Acetyltransferase (GNAT) family 76 161 7.9E-5 T 14-10-2018 IPR000182 GNAT domain MB46_08110 6bff2eb881b7995c41eb5cce54dc63f6 182 Gene3D G3DSA:3.40.630.30 42 182 9.8E-15 T 14-10-2018 MB46_03765 2c3fbfd551089add124119509fa77f58 371 SUPERFAMILY SSF63825 37 332 3.4E-14 T 14-10-2018 MB46_17255 4badd1803ad7ad174d8fa1e704e5d91e 117 Gene3D G3DSA:3.30.1050.40 1 117 1.1E-41 T 14-10-2018 MB46_16995 7cf172043f3a101831473ecbfaa90851 271 SUPERFAMILY SSF161098 8 268 3.83E-64 T 14-10-2018 IPR035906 MetI-like superfamily MB46_16995 7cf172043f3a101831473ecbfaa90851 271 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 87 261 5.0E-14 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_16995 7cf172043f3a101831473ecbfaa90851 271 Gene3D G3DSA:1.10.3720.10 7 262 1.4E-60 T 14-10-2018 IPR035906 MetI-like superfamily MB46_04570 51986d651d01b063781099b262b3d61f 599 TIGRFAM TIGR00360 ComEC_N-term: ComEC/Rec2-related protein 308 480 1.9E-19 T 14-10-2018 IPR004477 ComEC/Rec2-related protein MB46_04570 51986d651d01b063781099b262b3d61f 599 Pfam PF03772 Competence protein 286 544 1.0E-40 T 14-10-2018 IPR004477 ComEC/Rec2-related protein MB46_04570 51986d651d01b063781099b262b3d61f 599 Pfam PF13567 Domain of unknown function (DUF4131) 89 230 9.5E-7 T 14-10-2018 IPR025405 Domain of unknown function DUF4131 MB46_06030 a8d3a92a1ff08a65c2b74bea9cfa35fe 232 Pfam PF06283 Trehalose utilisation 6 230 1.2E-42 T 14-10-2018 IPR029010 ThuA-like domain MB46_06030 a8d3a92a1ff08a65c2b74bea9cfa35fe 232 SUPERFAMILY SSF52317 6 232 1.49E-40 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like MB46_06030 a8d3a92a1ff08a65c2b74bea9cfa35fe 232 Gene3D G3DSA:3.40.50.880 3 232 2.9E-36 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like MB46_06870 ca057f7e409f395a9134e079ab9db684 289 Gene3D G3DSA:1.20.58.480 26 289 1.2E-90 T 14-10-2018 MB46_06870 ca057f7e409f395a9134e079ab9db684 289 Hamap MF_01972 Tryptophan 2,3-dioxygenase [kynA]. 23 287 37.497 T 14-10-2018 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 MB46_06870 ca057f7e409f395a9134e079ab9db684 289 SUPERFAMILY SSF140959 28 287 7.06E-93 T 14-10-2018 IPR037217 Tryptophan/Indoleamine 2,3-dioxygenase-like GO:0019441|GO:0020037|GO:0046872 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 MB46_06870 ca057f7e409f395a9134e079ab9db684 289 Pfam PF03301 Tryptophan 2,3-dioxygenase 213 285 1.2E-19 T 14-10-2018 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 MB46_06870 ca057f7e409f395a9134e079ab9db684 289 Pfam PF03301 Tryptophan 2,3-dioxygenase 21 158 1.5E-37 T 14-10-2018 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 MB46_06870 ca057f7e409f395a9134e079ab9db684 289 TIGRFAM TIGR03036 trp_2_3_diox: tryptophan 2,3-dioxygenase 22 287 2.3E-118 T 14-10-2018 IPR017485 Tryptophan 2,3-dioxygenase, bacterial GO:0004833|GO:0019441 KEGG: 00380+1.13.11.11 MB46_11745 f6385008e8ec68d6dc87c33c0f666b21 317 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 36 289 2.7E-74 T 14-10-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 MB46_11745 f6385008e8ec68d6dc87c33c0f666b21 317 Pfam PF00809 Pterin binding enzyme 37 275 4.0E-64 T 14-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MB46_11745 f6385008e8ec68d6dc87c33c0f666b21 317 Gene3D G3DSA:3.20.20.20 26 302 2.4E-82 T 14-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MB46_11745 f6385008e8ec68d6dc87c33c0f666b21 317 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 36 51 - T 14-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MB46_11745 f6385008e8ec68d6dc87c33c0f666b21 317 SUPERFAMILY SSF51717 23 294 1.2E-77 T 14-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MB46_02340 e1f53f721c33f8c13b96d8243d27eb49 254 Pfam PF16976 Flp pilus assembly protein RcpC/CpaB 116 232 1.7E-10 T 14-10-2018 IPR031571 Flp pilus assembly protein RcpC/CpaB domain MB46_02340 e1f53f721c33f8c13b96d8243d27eb49 254 SMART SM00858 40 104 0.0013 T 14-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 MB46_08615 241c3e8c43c9d6f7903385b2b9265b97 266 Pfam PF00583 Acetyltransferase (GNAT) family 166 246 1.1E-11 T 14-10-2018 IPR000182 GNAT domain MB46_08615 241c3e8c43c9d6f7903385b2b9265b97 266 SUPERFAMILY SSF55729 64 254 3.55E-24 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase MB46_08615 241c3e8c43c9d6f7903385b2b9265b97 266 Gene3D G3DSA:3.40.630.30 18 259 4.6E-38 T 14-10-2018 MB46_17650 86d18568719750834535cd4b015f3aca 364 Gene3D G3DSA:3.90.230.10 137 347 6.6E-13 T 14-10-2018 MB46_17650 86d18568719750834535cd4b015f3aca 364 SUPERFAMILY SSF55920 138 348 2.62E-17 T 14-10-2018 IPR036005 Creatinase/aminopeptidase-like MB46_08925 f415a8cbd16542b8ca9a9fa73568f932 137 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 4 109 21.249 T 14-10-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS MB46_08925 f415a8cbd16542b8ca9a9fa73568f932 137 Pfam PF02410 Ribosomal silencing factor during starvation 14 108 2.1E-20 T 14-10-2018 MB46_08925 f415a8cbd16542b8ca9a9fa73568f932 137 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 12 108 5.0E-29 T 14-10-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS MB46_08925 f415a8cbd16542b8ca9a9fa73568f932 137 SUPERFAMILY SSF81301 7 118 2.78E-34 T 14-10-2018 MB46_08925 f415a8cbd16542b8ca9a9fa73568f932 137 Gene3D G3DSA:3.30.460.10 1 112 1.8E-35 T 14-10-2018 MB46_10365 13cde5cb40ef0ec0a70f1365c9340112 229 Pfam PF04586 Caudovirus prohead serine protease 13 164 8.2E-40 T 14-10-2018 IPR006433 Prohead protease MB46_10365 13cde5cb40ef0ec0a70f1365c9340112 229 TIGRFAM TIGR01543 proheadase_HK97: phage prohead protease, HK97 family 24 160 4.6E-21 T 14-10-2018 IPR006433 Prohead protease MB46_11020 3856fac0911a9d5083b1db40d3dec3cb 351 Gene3D G3DSA:3.40.50.720 100 350 6.0E-68 T 14-10-2018 MB46_11020 3856fac0911a9d5083b1db40d3dec3cb 351 SUPERFAMILY SSF51735 108 349 1.37E-63 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_11020 3856fac0911a9d5083b1db40d3dec3cb 351 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 256 275 5.5E-7 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_11020 3856fac0911a9d5083b1db40d3dec3cb 351 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 182 193 5.5E-7 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_11020 3856fac0911a9d5083b1db40d3dec3cb 351 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 236 244 5.5E-7 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_11020 3856fac0911a9d5083b1db40d3dec3cb 351 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 193 1.4E-27 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_11020 3856fac0911a9d5083b1db40d3dec3cb 351 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 113 130 1.4E-27 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_11020 3856fac0911a9d5083b1db40d3dec3cb 351 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 256 275 1.4E-27 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_11020 3856fac0911a9d5083b1db40d3dec3cb 351 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 230 246 1.4E-27 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_11020 3856fac0911a9d5083b1db40d3dec3cb 351 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 277 294 1.4E-27 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_11020 3856fac0911a9d5083b1db40d3dec3cb 351 Pfam PF00106 short chain dehydrogenase 112 299 9.9E-53 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_01795 6950690513fe3276895a161068952e92 543 Gene3D G3DSA:1.10.405.40 108 244 6.3E-193 T 14-10-2018 MB46_01795 6950690513fe3276895a161068952e92 543 SUPERFAMILY SSF54373 343 458 2.81E-28 T 14-10-2018 MB46_01795 6950690513fe3276895a161068952e92 543 Pfam PF01593 Flavin containing amine oxidoreductase 39 513 6.2E-45 T 14-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 MB46_01795 6950690513fe3276895a161068952e92 543 Gene3D G3DSA:3.50.50.60 18 528 6.3E-193 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_01795 6950690513fe3276895a161068952e92 543 SUPERFAMILY SSF51905 29 521 1.04E-40 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_01795 6950690513fe3276895a161068952e92 543 Gene3D G3DSA:3.90.660.10 68 464 6.3E-193 T 14-10-2018 MB46_17145 10459af7c0ab4b184ecd5d8fc869855f 375 Gene3D G3DSA:1.20.1530.20 2 373 5.0E-41 T 14-10-2018 IPR038770 Sodium/solute symporter superfamily MB46_17145 10459af7c0ab4b184ecd5d8fc869855f 375 Pfam PF00999 Sodium/hydrogen exchanger family 8 361 2.3E-31 T 14-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 MB46_05220 c93a00854b1062c79dac90ba7b171045 246 SUPERFAMILY SSF51735 1 241 7.09E-37 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_05220 c93a00854b1062c79dac90ba7b171045 246 Pfam PF00106 short chain dehydrogenase 7 191 3.7E-22 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_05220 c93a00854b1062c79dac90ba7b171045 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 1.6E-7 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_05220 c93a00854b1062c79dac90ba7b171045 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 1.6E-7 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_05220 c93a00854b1062c79dac90ba7b171045 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.6E-7 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_05220 c93a00854b1062c79dac90ba7b171045 246 Gene3D G3DSA:3.40.50.720 1 243 3.8E-34 T 14-10-2018 MB46_11370 4454e5e34a265d832806c3fc6b430c1f 407 Pfam PF00437 Type II/IV secretion system protein 72 344 1.3E-54 T 14-10-2018 IPR001482 Type II/IV secretion system protein MB46_11370 4454e5e34a265d832806c3fc6b430c1f 407 Gene3D G3DSA:3.40.50.300 166 381 7.0E-49 T 14-10-2018 MB46_11370 4454e5e34a265d832806c3fc6b430c1f 407 Gene3D G3DSA:3.30.450.380 2 164 2.9E-31 T 14-10-2018 MB46_11370 4454e5e34a265d832806c3fc6b430c1f 407 SUPERFAMILY SSF52540 60 350 4.69E-44 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_11655 f07e8946fa0a540ce3d5bb91cb0aed44 226 Pfam PF13559 Domain of unknown function (DUF4129) 139 207 1.1E-12 T 14-10-2018 IPR025403 Domain of unknown function DUF4129 MB46_00945 a7db94bcecd0e2bed3c2a043a06781ee 313 SUPERFAMILY SSF51658 5 310 8.29E-26 T 14-10-2018 IPR036237 Xylose isomerase-like superfamily MB46_00945 a7db94bcecd0e2bed3c2a043a06781ee 313 Gene3D G3DSA:3.20.20.150 3 299 4.6E-34 T 14-10-2018 MB46_00945 a7db94bcecd0e2bed3c2a043a06781ee 313 Pfam PF01261 Xylose isomerase-like TIM barrel 21 250 3.5E-18 T 14-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain MB46_11885 cab769fc46a493ba44aebf4a899113df 317 SUPERFAMILY SSF81342 74 281 3.45E-17 T 14-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 MB46_11885 cab769fc46a493ba44aebf4a899113df 317 Pfam PF01292 Prokaryotic cytochrome b561 76 272 1.4E-10 T 14-10-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 MB46_11885 cab769fc46a493ba44aebf4a899113df 317 Gene3D G3DSA:1.20.950.20 74 266 9.0E-8 T 14-10-2018 MB46_13445 0b536e58f88aa84dc9fd570aa8a904af 418 Pfam PF07690 Major Facilitator Superfamily 254 410 4.7E-16 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MB46_13445 0b536e58f88aa84dc9fd570aa8a904af 418 SUPERFAMILY SSF103473 19 411 1.07E-37 T 14-10-2018 IPR036259 MFS transporter superfamily MB46_13445 0b536e58f88aa84dc9fd570aa8a904af 418 Gene3D G3DSA:1.20.1250.20 17 207 5.2E-14 T 14-10-2018 MB46_13445 0b536e58f88aa84dc9fd570aa8a904af 418 ProSitePatterns PS00216 Sugar transport proteins signature 1. 292 309 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MB46_13445 0b536e58f88aa84dc9fd570aa8a904af 418 Gene3D G3DSA:1.20.1250.20 234 416 1.7E-19 T 14-10-2018 MB46_01210 1b3b9d0d36f2e908e4e27e197449e02b 364 Gene3D G3DSA:1.20.1530.20 24 362 1.3E-25 T 14-10-2018 IPR038770 Sodium/solute symporter superfamily MB46_01210 1b3b9d0d36f2e908e4e27e197449e02b 364 PIRSF PIRSF005508 12 364 1.2E-135 T 14-10-2018 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 MB46_01210 1b3b9d0d36f2e908e4e27e197449e02b 364 Pfam PF01758 Sodium Bile acid symporter family 70 266 5.0E-59 T 14-10-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 MB46_01210 1b3b9d0d36f2e908e4e27e197449e02b 364 TIGRFAM TIGR00832 acr3: arsenical-resistance protein 25 354 6.1E-128 T 14-10-2018 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 MB46_01865 8af0ebe6a8b40fd9a25e088bc5dd2629 246 Pfam PF00440 Bacterial regulatory proteins, tetR family 38 82 9.0E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MB46_01865 8af0ebe6a8b40fd9a25e088bc5dd2629 246 SUPERFAMILY SSF46689 27 107 1.9E-14 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MB46_01865 8af0ebe6a8b40fd9a25e088bc5dd2629 246 Gene3D G3DSA:1.10.357.10 29 226 2.7E-28 T 14-10-2018 MB46_08810 cd7614704f7496f93ef04c441f9aae30 158 TIGRFAM TIGR00333 nrdI: nrdI protein 23 149 6.9E-45 T 14-10-2018 IPR004465 Ribonucleotide reductase Class Ib, NrdI MB46_08810 cd7614704f7496f93ef04c441f9aae30 158 Pfam PF07972 NrdI Flavodoxin like 23 141 2.6E-44 T 14-10-2018 IPR004465 Ribonucleotide reductase Class Ib, NrdI MB46_08810 cd7614704f7496f93ef04c441f9aae30 158 Hamap MF_00128 Protein NrdI [nrdI]. 21 151 31.848 T 14-10-2018 IPR020852 Ribonucleotide reductase, class Ib, NrdI, bacterial MB46_08810 cd7614704f7496f93ef04c441f9aae30 158 PIRSF PIRSF005087 19 155 4.1E-51 T 14-10-2018 IPR004465 Ribonucleotide reductase Class Ib, NrdI MB46_08810 cd7614704f7496f93ef04c441f9aae30 158 Gene3D G3DSA:3.40.50.360 21 152 5.3E-44 T 14-10-2018 IPR029039 Flavoprotein-like superfamily MB46_08810 cd7614704f7496f93ef04c441f9aae30 158 SUPERFAMILY SSF52218 18 150 2.29E-24 T 14-10-2018 IPR029039 Flavoprotein-like superfamily MB46_05935 031ce9696b0a28d40d272e1bdeb37c3b 735 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 105 553 5.8E-134 T 14-10-2018 IPR000060 BCCT transporter family GO:0016020|GO:0022857|GO:0071705 MB46_05935 031ce9696b0a28d40d272e1bdeb37c3b 735 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 67 553 1.1E-146 T 14-10-2018 IPR000060 BCCT transporter family GO:0016020|GO:0022857|GO:0071705 MB46_00250 12bb6d85186bd22234da888231a49a5d 318 Gene3D G3DSA:2.115.10.20 37 311 4.3E-20 T 14-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily MB46_00250 12bb6d85186bd22234da888231a49a5d 318 SUPERFAMILY SSF75005 53 309 1.28E-23 T 14-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily MB46_03455 5283be7959cc733f7fa7567ef1e015b5 365 Pfam PF04233 Phage Mu protein F like protein 160 253 7.4E-11 T 14-10-2018 IPR006528 Phage head morphogenesis domain MB46_06905 9ba6fbac9b57510ef77084d78f9986f6 292 Pfam PF03180 NLPA lipoprotein 36 266 1.1E-63 T 14-10-2018 IPR004872 Lipoprotein NlpA family MB46_06905 9ba6fbac9b57510ef77084d78f9986f6 292 Gene3D G3DSA:3.40.190.10 113 221 5.3E-75 T 14-10-2018 MB46_06905 9ba6fbac9b57510ef77084d78f9986f6 292 Gene3D G3DSA:3.40.190.10 37 261 5.3E-75 T 14-10-2018 MB46_06905 9ba6fbac9b57510ef77084d78f9986f6 292 SUPERFAMILY SSF53850 35 266 4.22E-59 T 14-10-2018 MB46_10015 03bede81b734647b191bd0effaff0483 258 Gene3D G3DSA:3.90.850.10 36 258 7.6E-81 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 MB46_10015 03bede81b734647b191bd0effaff0483 258 Pfam PF10370 Domain of unknown function (DUF2437) 1 55 8.0E-13 T 14-10-2018 IPR018833 Domain of unknown function DUF2437 MB46_10015 03bede81b734647b191bd0effaff0483 258 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 61 256 2.3E-62 T 14-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 MB46_10015 03bede81b734647b191bd0effaff0483 258 SUPERFAMILY SSF56529 50 256 4.71E-76 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 MB46_06610 0c4b07d807d6d939eec3dbf55b044c08 499 Gene3D G3DSA:3.20.20.370 38 191 2.1E-26 T 14-10-2018 MB46_06610 0c4b07d807d6d939eec3dbf55b044c08 499 Pfam PF00395 S-layer homology domain 376 422 7.6E-8 T 14-10-2018 IPR001119 S-layer homology domain MB46_06610 0c4b07d807d6d939eec3dbf55b044c08 499 Pfam PF00395 S-layer homology domain 310 357 3.0E-6 T 14-10-2018 IPR001119 S-layer homology domain MB46_06610 0c4b07d807d6d939eec3dbf55b044c08 499 Pfam PF00395 S-layer homology domain 439 484 9.1E-7 T 14-10-2018 IPR001119 S-layer homology domain MB46_06610 0c4b07d807d6d939eec3dbf55b044c08 499 Pfam PF01522 Polysaccharide deacetylase 56 177 1.6E-19 T 14-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 MB46_06610 0c4b07d807d6d939eec3dbf55b044c08 499 SUPERFAMILY SSF88713 56 249 1.53E-25 T 14-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 MB46_00880 38421e0710fd60b4eb423f77d6cd53b3 476 Pfam PF02687 FtsX-like permease family 336 467 6.6E-12 T 14-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 MB46_05400 7670e5e576e4b584b63c622d45c42d40 532 PIRSF PIRSF018077 10 524 5.6E-172 T 14-10-2018 IPR004347 Pup ligase/deamidase GO:0010498|GO:0019941 MetaCyc: PWY-7893 MB46_05400 7670e5e576e4b584b63c622d45c42d40 532 Pfam PF03136 Pup-ligase protein 5 481 3.5E-177 T 14-10-2018 IPR004347 Pup ligase/deamidase GO:0010498|GO:0019941 MetaCyc: PWY-7893 MB46_05400 7670e5e576e4b584b63c622d45c42d40 532 TIGRFAM TIGR03688 pupylate_PafA2: proteasome accessory factor PafA2 5 513 1.0E-193 T 14-10-2018 IPR022366 Pup deamidase GO:0008233|GO:0016811 MB46_07510 0711b4aebf3d3f07e7e3488a4e493e04 391 SUPERFAMILY SSF103473 7 383 1.31E-44 T 14-10-2018 IPR036259 MFS transporter superfamily MB46_07510 0711b4aebf3d3f07e7e3488a4e493e04 391 Pfam PF07690 Major Facilitator Superfamily 12 313 6.9E-28 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MB46_07510 0711b4aebf3d3f07e7e3488a4e493e04 391 Gene3D G3DSA:1.20.1250.20 2 377 2.8E-36 T 14-10-2018 MB46_00300 b9b4018298f1cc7f30608a650b4635fc 303 SUPERFAMILY SSF51658 5 276 1.24E-42 T 14-10-2018 IPR036237 Xylose isomerase-like superfamily MB46_00300 b9b4018298f1cc7f30608a650b4635fc 303 Gene3D G3DSA:3.20.20.150 1 295 1.7E-52 T 14-10-2018 MB46_00300 b9b4018298f1cc7f30608a650b4635fc 303 Pfam PF01261 Xylose isomerase-like TIM barrel 32 220 1.0E-22 T 14-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain MB46_02170 29256f0ff3766fc3b52ecb32e40b825c 497 Pfam PF03600 Citrate transporter 13 442 8.7E-47 T 14-10-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 MB46_07000 1c9eaaed23c637454a27f101e880f1ac 224 Pfam PF05719 Golgi phosphoprotein 3 (GPP34) 8 204 1.9E-34 T 14-10-2018 IPR008628 Golgi phosphoprotein 3-like GO:0070273 MB46_07000 1c9eaaed23c637454a27f101e880f1ac 224 Gene3D G3DSA:1.10.3630.10 5 212 6.2E-12 T 14-10-2018 IPR038261 Golgi phosphoprotein 3-like domain superfamily MB46_04800 98874ba8a539841c8cb13a3ac5a66f2c 485 Pfam PF01145 SPFH domain / Band 7 family 59 212 6.6E-14 T 14-10-2018 IPR001107 Band 7 domain MB46_04800 98874ba8a539841c8cb13a3ac5a66f2c 485 SUPERFAMILY SSF117892 66 203 1.31E-24 T 14-10-2018 IPR036013 Band 7/SPFH domain superfamily MB46_04800 98874ba8a539841c8cb13a3ac5a66f2c 485 Gene3D G3DSA:3.30.479.30 74 188 2.3E-29 T 14-10-2018 MB46_04800 98874ba8a539841c8cb13a3ac5a66f2c 485 Pfam PF15975 Flotillin 355 447 8.0E-10 T 14-10-2018 IPR031905 Flotillin, C-terminal domain Reactome: R-HSA-8849932 MB46_19640 dbc20040eafd0d1f3e522365c1bad449 180 Pfam PF13302 Acetyltransferase (GNAT) domain 7 144 7.3E-19 T 14-10-2018 IPR000182 GNAT domain MB46_19640 dbc20040eafd0d1f3e522365c1bad449 180 Gene3D G3DSA:3.40.630.30 1 153 3.0E-26 T 14-10-2018 MB46_19640 dbc20040eafd0d1f3e522365c1bad449 180 SUPERFAMILY SSF55729 2 147 1.92E-24 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase MB46_19285 686cc6eb90baf069474a12d323be13fe 87 Pfam PF00462 Glutaredoxin 3 60 8.5E-11 T 14-10-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 MB46_19285 686cc6eb90baf069474a12d323be13fe 87 SUPERFAMILY SSF52833 1 60 3.29E-12 T 14-10-2018 IPR036249 Thioredoxin-like superfamily MB46_19285 686cc6eb90baf069474a12d323be13fe 87 Gene3D G3DSA:3.40.30.10 1 82 2.3E-20 T 14-10-2018 MB46_10620 fdfd25be4d64de3a60c97c89435f2c56 323 Pfam PF01032 FecCD transport family 7 317 1.5E-90 T 14-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 MB46_10620 fdfd25be4d64de3a60c97c89435f2c56 323 Gene3D G3DSA:1.10.3470.10 1 322 3.6E-92 T 14-10-2018 IPR037294 ABC transporter, BtuC-like MB46_10620 fdfd25be4d64de3a60c97c89435f2c56 323 SUPERFAMILY SSF81345 3 318 2.75E-78 T 14-10-2018 IPR037294 ABC transporter, BtuC-like MB46_13610 a946ed088ff8993bd61434402a1bbb3c 611 Pfam PF07940 Heparinase II/III-like protein 375 539 6.0E-9 T 14-10-2018 IPR012480 Heparinase II/III-like GO:0016829 MB46_13610 a946ed088ff8993bd61434402a1bbb3c 611 Gene3D G3DSA:2.70.98.70 361 506 1.3E-9 T 14-10-2018 MB46_13610 a946ed088ff8993bd61434402a1bbb3c 611 SUPERFAMILY SSF48230 161 323 6.87E-8 T 14-10-2018 IPR008929 Chondroitin AC/alginate lyase Reactome: R-HSA-2022923 MB46_13610 a946ed088ff8993bd61434402a1bbb3c 611 Gene3D G3DSA:1.50.10.100 3 326 1.1E-37 T 14-10-2018 IPR008929 Chondroitin AC/alginate lyase Reactome: R-HSA-2022923 MB46_18200 19e94f400839fe5c2593396f25466249 301 SUPERFAMILY SSF51445 116 295 2.53E-9 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily MB46_14905 630ab4eece19761da9e5f32c9cb8bccd 195 Gene3D G3DSA:3.20.20.370 5 195 2.1E-34 T 14-10-2018 MB46_14905 630ab4eece19761da9e5f32c9cb8bccd 195 Pfam PF01522 Polysaccharide deacetylase 12 132 9.7E-21 T 14-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 MB46_14905 630ab4eece19761da9e5f32c9cb8bccd 195 SUPERFAMILY SSF88713 4 192 1.8E-35 T 14-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 MB46_06190 c09b14ea0942b471cb3fb9f4236ca18c 615 SUPERFAMILY SSF51695 361 586 4.71E-48 T 14-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 MB46_06190 c09b14ea0942b471cb3fb9f4236ca18c 615 Pfam PF10110 Membrane domain of glycerophosphoryl diester phosphodiesterase 26 278 6.1E-15 T 14-10-2018 IPR018476 Glycerophosphoryl diester phosphodiesterase, membrane domain MB46_06190 c09b14ea0942b471cb3fb9f4236ca18c 615 Gene3D G3DSA:3.20.20.190 351 589 6.3E-45 T 14-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 MB46_06190 c09b14ea0942b471cb3fb9f4236ca18c 615 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 365 582 3.8E-21 T 14-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 MB46_02265 7f5ec5412d9956ce82130d1b7e4c6bce 182 Pfam PF06262 Zincin-like metallopeptidase 86 175 1.2E-11 T 14-10-2018 IPR010428 Zincin-like metallopeptidase MB46_02265 7f5ec5412d9956ce82130d1b7e4c6bce 182 SUPERFAMILY SSF55486 61 175 6.23E-21 T 14-10-2018 MB46_02265 7f5ec5412d9956ce82130d1b7e4c6bce 182 Gene3D G3DSA:3.30.2010.20 59 175 3.7E-11 T 14-10-2018 IPR038555 Zincin-like metallopeptidase superfamily MB46_15605 9af3443b693cfbc75b3e8a2f26fdaa87 125 Pfam PF13828 Domain of unknown function (DUF4190) 47 105 1.1E-10 T 14-10-2018 IPR025241 Domain of unknown function DUF4190 MB46_16970 d7e3b09975828446404f3f834dec90f4 210 Pfam PF09819 ABC-type cobalt transport system, permease component 25 145 4.9E-39 T 14-10-2018 IPR017195 ABC-type thiamin-related transport system, permease component 1, predicted MB46_16970 d7e3b09975828446404f3f834dec90f4 210 PIRSF PIRSF037394 15 209 1.1E-54 T 14-10-2018 IPR017195 ABC-type thiamin-related transport system, permease component 1, predicted MB46_17320 a4f5565e07132def7489dfab0602a410 161 SUPERFAMILY SSF55298 11 159 1.19E-55 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 MB46_17320 a4f5565e07132def7489dfab0602a410 161 Pfam PF14588 YjgF/chorismate_mutase-like, putative endoribonuclease 13 159 2.8E-38 T 14-10-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like MB46_17320 a4f5565e07132def7489dfab0602a410 161 Gene3D G3DSA:3.30.1330.40 8 160 3.1E-61 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 MB46_03545 a3b506fb9908d233ea098d01eb9f94e4 538 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 44 456 1.7E-56 T 14-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 MB46_03545 a3b506fb9908d233ea098d01eb9f94e4 538 Pfam PF00474 Sodium:solute symporter family 44 456 2.3E-92 T 14-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 MB46_03545 a3b506fb9908d233ea098d01eb9f94e4 538 Gene3D G3DSA:1.20.1730.10 13 510 1.7E-53 T 14-10-2018 IPR038377 Sodium/glucose symporter superfamily MB46_07515 daa5d3c0550251908cf8c018a839cca4 103 Pfam PF12840 Helix-turn-helix domain 6 80 9.7E-8 T 14-10-2018 MB46_07515 daa5d3c0550251908cf8c018a839cca4 103 SMART SM00418 5 101 3.8E-6 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MB46_07515 daa5d3c0550251908cf8c018a839cca4 103 Gene3D G3DSA:1.10.10.10 2 102 4.6E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_07515 daa5d3c0550251908cf8c018a839cca4 103 SUPERFAMILY SSF46785 5 99 9.73E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_12605 afb6d696e2392c3e56e4faafae8d7dd0 144 SUPERFAMILY SSF159888 40 113 6.28E-8 T 14-10-2018 MB46_09105 185267790fbc08e6e97d1b89753df632 160 Pfam PF02566 OsmC-like protein 53 148 2.9E-13 T 14-10-2018 IPR003718 OsmC/Ohr family MB46_09105 185267790fbc08e6e97d1b89753df632 160 SUPERFAMILY SSF82784 5 150 7.98E-39 T 14-10-2018 IPR036102 OsmC/Ohr superfamily MB46_09105 185267790fbc08e6e97d1b89753df632 160 Gene3D G3DSA:3.30.300.20 1 151 6.7E-45 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta MB46_16990 3d030a16471a0e4d45899811b9c2c671 300 SUPERFAMILY SSF161098 60 287 3.01E-58 T 14-10-2018 IPR035906 MetI-like superfamily MB46_16990 3d030a16471a0e4d45899811b9c2c671 300 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 94 296 2.2E-17 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_16990 3d030a16471a0e4d45899811b9c2c671 300 Gene3D G3DSA:1.10.3720.10 55 299 2.0E-70 T 14-10-2018 IPR035906 MetI-like superfamily MB46_13715 6986330c89f93c9f722e95f5844bce1b 333 Pfam PF13338 Transcriptional regulator, AbiEi antitoxin 9 40 6.5E-6 T 14-10-2018 IPR025159 Transcriptional regulator, AbiEi antitoxin MB46_10730 196aec18b3f0b371459746d4c82f3214 265 Gene3D G3DSA:3.60.15.10 1 265 2.8E-66 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MB46_10730 196aec18b3f0b371459746d4c82f3214 265 SUPERFAMILY SSF56281 1 265 1.18E-46 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MB46_10730 196aec18b3f0b371459746d4c82f3214 265 Pfam PF12706 Beta-lactamase superfamily domain 34 233 1.5E-20 T 14-10-2018 IPR001279 Metallo-beta-lactamase MB46_10730 196aec18b3f0b371459746d4c82f3214 265 SMART SM00849 18 213 0.0069 T 14-10-2018 IPR001279 Metallo-beta-lactamase MB46_06315 5c2de36583b9b101fd89b74bf9e2e19f 301 Gene3D G3DSA:3.40.50.1820 27 286 1.1E-41 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_06315 5c2de36583b9b101fd89b74bf9e2e19f 301 SUPERFAMILY SSF53474 34 282 4.69E-42 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_06315 5c2de36583b9b101fd89b74bf9e2e19f 301 Pfam PF12697 Alpha/beta hydrolase family 45 275 5.6E-18 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MB46_08380 77675f91ae5e9f4ac280c41729d72f4a 243 Gene3D G3DSA:1.10.1660.10 22 243 8.3E-28 T 14-10-2018 MB46_08380 77675f91ae5e9f4ac280c41729d72f4a 243 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 56 76 3.3E-5 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MB46_08380 77675f91ae5e9f4ac280c41729d72f4a 243 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 33 46 3.3E-5 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MB46_08380 77675f91ae5e9f4ac280c41729d72f4a 243 Pfam PF00376 MerR family regulatory protein 17 58 4.0E-14 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MB46_08380 77675f91ae5e9f4ac280c41729d72f4a 243 SUPERFAMILY SSF46955 27 118 1.14E-17 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily MB46_08380 77675f91ae5e9f4ac280c41729d72f4a 243 SMART SM00422 16 90 8.0E-22 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MB46_01715 a0c552f811110c468595db4b3daac5f7 335 Pfam PF02653 Branched-chain amino acid transport system / permease component 32 318 1.4E-48 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 MB46_17040 27217ac8846ad6d500be7c8294a0010a 200 Pfam PF03729 Short repeat of unknown function (DUF308) 148 193 2.0E-5 T 14-10-2018 IPR005325 Protein of unknown function DUF308, membrane MB46_17040 27217ac8846ad6d500be7c8294a0010a 200 Pfam PF03729 Short repeat of unknown function (DUF308) 32 103 1.8E-9 T 14-10-2018 IPR005325 Protein of unknown function DUF308, membrane MB46_17040 27217ac8846ad6d500be7c8294a0010a 200 Pfam PF03729 Short repeat of unknown function (DUF308) 113 160 0.0053 T 14-10-2018 IPR005325 Protein of unknown function DUF308, membrane MB46_00385 80268330d3de4ef6a3da3524a15bf640 358 Pfam PF01497 Periplasmic binding protein 75 295 1.8E-18 T 14-10-2018 IPR002491 ABC transporter periplasmic binding domain MB46_00385 80268330d3de4ef6a3da3524a15bf640 358 SUPERFAMILY SSF53807 55 351 3.41E-38 T 14-10-2018 MB46_00385 80268330d3de4ef6a3da3524a15bf640 358 Gene3D G3DSA:3.40.50.1980 50 193 1.6E-35 T 14-10-2018 MB46_00385 80268330d3de4ef6a3da3524a15bf640 358 Gene3D G3DSA:3.40.50.1980 196 357 2.8E-38 T 14-10-2018 MB46_04275 9438a219801bbb591fe41024bb3f16dc 230 Gene3D G3DSA:3.90.79.10 26 230 8.5E-56 T 14-10-2018 MB46_04275 9438a219801bbb591fe41024bb3f16dc 230 SUPERFAMILY SSF55811 33 204 7.85E-40 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 MB46_04275 9438a219801bbb591fe41024bb3f16dc 230 Pfam PF00293 NUDIX domain 67 184 1.4E-18 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MB46_13555 4dba8954f678228bf1c7d5cb834b345d 442 Pfam PF04024 PspC domain 51 99 2.8E-13 T 14-10-2018 IPR007168 Phage shock protein, PspC, N-terminal MB46_13995 4b7531cf5662813c66ace1fb9435427b 92 Pfam PF03992 Antibiotic biosynthesis monooxygenase 7 74 1.3E-9 T 14-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain MB46_13995 4b7531cf5662813c66ace1fb9435427b 92 SUPERFAMILY SSF54909 1 86 8.26E-13 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel MB46_13995 4b7531cf5662813c66ace1fb9435427b 92 Gene3D G3DSA:3.30.70.100 1 92 1.8E-16 T 14-10-2018 MB46_12015 65ab484ddf4fdd14507ee64359119e56 245 SMART SM00382 33 218 1.6E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_12015 65ab484ddf4fdd14507ee64359119e56 245 PIRSF PIRSF039085 6 245 2.4E-99 T 14-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 MB46_12015 65ab484ddf4fdd14507ee64359119e56 245 Gene3D G3DSA:3.40.50.300 8 245 1.7E-76 T 14-10-2018 MB46_12015 65ab484ddf4fdd14507ee64359119e56 245 SUPERFAMILY SSF52540 10 240 8.87E-75 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_12015 65ab484ddf4fdd14507ee64359119e56 245 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MB46_12015 65ab484ddf4fdd14507ee64359119e56 245 Pfam PF00005 ABC transporter 24 170 2.3E-37 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_03655 b8b1e2d81c01fe9d079631d066128388 516 Pfam PF02435 Levansucrase/Invertase 45 492 1.4E-143 T 14-10-2018 IPR003469 Glycoside hydrolase, family 68 GO:0009758|GO:0050053 MB46_03655 b8b1e2d81c01fe9d079631d066128388 516 SUPERFAMILY SSF75005 39 490 5.67E-70 T 14-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily MB46_03655 b8b1e2d81c01fe9d079631d066128388 516 Gene3D G3DSA:2.115.10.20 24 505 1.6E-206 T 14-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily MB46_00170 f6b159f34a5e9486dd745ce296d309ad 518 Pfam PF08244 Glycosyl hydrolases family 32 C terminal 344 505 2.3E-18 T 14-10-2018 IPR013189 Glycosyl hydrolase family 32, C-terminal MB46_00170 f6b159f34a5e9486dd745ce296d309ad 518 SUPERFAMILY SSF49899 341 507 3.32E-20 T 14-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily MB46_00170 f6b159f34a5e9486dd745ce296d309ad 518 SMART SM00640 30 473 2.6E-112 T 14-10-2018 IPR001362 Glycoside hydrolase, family 32 GO:0004553|GO:0005975 MB46_00170 f6b159f34a5e9486dd745ce296d309ad 518 Pfam PF00251 Glycosyl hydrolases family 32 N-terminal domain 30 339 3.3E-76 T 14-10-2018 IPR013148 Glycosyl hydrolase family 32, N-terminal MB46_00170 f6b159f34a5e9486dd745ce296d309ad 518 Gene3D G3DSA:2.60.120.560 356 515 1.9E-25 T 14-10-2018 MB46_00170 f6b159f34a5e9486dd745ce296d309ad 518 SUPERFAMILY SSF75005 22 342 6.44E-89 T 14-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily MB46_00170 f6b159f34a5e9486dd745ce296d309ad 518 Gene3D G3DSA:2.115.10.20 10 355 1.1E-106 T 14-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily MB46_01130 2fc3c77b77b6d5f7d428c48a256cc789 75 SUPERFAMILY SSF51230 3 75 4.06E-12 T 14-10-2018 IPR011053 Single hybrid motif MB46_01130 2fc3c77b77b6d5f7d428c48a256cc789 75 Pfam PF00364 Biotin-requiring enzyme 2 74 1.1E-12 T 14-10-2018 IPR000089 Biotin/lipoyl attachment MB46_01130 2fc3c77b77b6d5f7d428c48a256cc789 75 Gene3D G3DSA:2.40.50.100 12 75 1.1E-14 T 14-10-2018 MB46_17395 b90ba852cb08126a9e83dd767326b6a3 394 SUPERFAMILY SSF52540 140 347 5.31E-18 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_17395 b90ba852cb08126a9e83dd767326b6a3 394 TIGRFAM TIGR03815 CpaE_hom_Actino: helicase/secretion neighborhood CpaE-like protein 30 370 5.9E-74 T 14-10-2018 IPR022521 Conserved hypothetical protein CHP03815, CpaE-like MB46_17395 b90ba852cb08126a9e83dd767326b6a3 394 Gene3D G3DSA:3.40.50.300 139 353 1.4E-20 T 14-10-2018 MB46_08425 21a55e90ebef568aadf1a92e508f7511 236 Pfam PF07947 YhhN family 36 220 4.2E-24 T 14-10-2018 IPR012506 YhhN-like GO:0016021 MB46_02465 89f54f4178c18f7112dcffc5aae345bd 190 ProSitePatterns PS01195 Peptidyl-tRNA hydrolase signature 1. 17 30 - T 14-10-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 MB46_02465 89f54f4178c18f7112dcffc5aae345bd 190 Pfam PF01195 Peptidyl-tRNA hydrolase 6 189 6.3E-51 T 14-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 MB46_02465 89f54f4178c18f7112dcffc5aae345bd 190 Gene3D G3DSA:3.40.50.1470 1 190 9.3E-64 T 14-10-2018 IPR036416 Peptidyl-tRNA hydrolase superfamily GO:0004045 MetaCyc: PWY-6308 MB46_02465 89f54f4178c18f7112dcffc5aae345bd 190 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 112 122 - T 14-10-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 MB46_02465 89f54f4178c18f7112dcffc5aae345bd 190 SUPERFAMILY SSF53178 4 190 7.72E-60 T 14-10-2018 IPR036416 Peptidyl-tRNA hydrolase superfamily GO:0004045 MetaCyc: PWY-6308 MB46_02465 89f54f4178c18f7112dcffc5aae345bd 190 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 6 190 2.1E-52 T 14-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 MB46_02465 89f54f4178c18f7112dcffc5aae345bd 190 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 4 183 32.388 T 14-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 MB46_09695 6921dab15459aacb2edabd78ae590e87 380 Gene3D G3DSA:3.20.20.30 3 380 7.4E-78 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 MB46_09695 6921dab15459aacb2edabd78ae590e87 380 Pfam PF00296 Luciferase-like monooxygenase 24 325 5.1E-22 T 14-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MB46_09695 6921dab15459aacb2edabd78ae590e87 380 SUPERFAMILY SSF51679 12 371 4.21E-49 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 MB46_01305 3f9d2f663b5a5f2466cf0a190cd6390c 259 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 152 180 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MB46_01305 3f9d2f663b5a5f2466cf0a190cd6390c 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 1.4E-29 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_01305 3f9d2f663b5a5f2466cf0a190cd6390c 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 220 240 1.4E-29 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_01305 3f9d2f663b5a5f2466cf0a190cd6390c 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 184 1.4E-29 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_01305 3f9d2f663b5a5f2466cf0a190cd6390c 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 186 203 1.4E-29 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_01305 3f9d2f663b5a5f2466cf0a190cd6390c 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 137 153 1.4E-29 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_01305 3f9d2f663b5a5f2466cf0a190cd6390c 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 90 101 1.4E-29 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_01305 3f9d2f663b5a5f2466cf0a190cd6390c 259 Gene3D G3DSA:3.40.50.720 5 258 2.3E-70 T 14-10-2018 MB46_01305 3f9d2f663b5a5f2466cf0a190cd6390c 259 SUPERFAMILY SSF51735 11 258 4.42E-72 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_01305 3f9d2f663b5a5f2466cf0a190cd6390c 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 165 184 1.6E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_01305 3f9d2f663b5a5f2466cf0a190cd6390c 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 90 101 1.6E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_01305 3f9d2f663b5a5f2466cf0a190cd6390c 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 143 151 1.6E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MB46_01305 3f9d2f663b5a5f2466cf0a190cd6390c 259 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 256 4.7E-61 T 14-10-2018 MB46_11620 13ae3fd308288cb6aa809addb92b698c 403 Pfam PF06224 Winged helix DNA-binding domain 39 380 3.0E-67 T 14-10-2018 IPR009351 Protein of unknown function DUF1006 MB46_16915 c95aa79c08808038dc5b6be998fa144e 392 Pfam PF00999 Sodium/hydrogen exchanger family 19 369 4.1E-44 T 14-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 MB46_16915 c95aa79c08808038dc5b6be998fa144e 392 Gene3D G3DSA:1.20.1530.20 5 381 7.5E-56 T 14-10-2018 IPR038770 Sodium/solute symporter superfamily MB46_13860 a773dc009286bdb875cfffa0a096accf 551 Pfam PF03814 Potassium-transporting ATPase A subunit 14 549 1.7E-207 T 14-10-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 MB46_13860 a773dc009286bdb875cfffa0a096accf 551 PIRSF PIRSF001294 4 551 2.2E-195 T 14-10-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 MB46_13860 a773dc009286bdb875cfffa0a096accf 551 TIGRFAM TIGR00680 kdpA: K+-transporting ATPase, A subunit 11 549 8.9E-182 T 14-10-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 MB46_13860 a773dc009286bdb875cfffa0a096accf 551 Hamap MF_00275 Potassium-transporting ATPase potassium-binding subunit [kdpA]. 5 551 30.741 T 14-10-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 MB46_18960 2e25fcce2e30ba4b7e4060ee5cce2f4e 66 Pfam PF04328 Selenoprotein, putative 12 66 1.8E-18 T 14-10-2018 IPR007423 Selenoprotein, putative MB46_12160 9816421af654000aa5114715dd6cfd51 492 Pfam PF13515 Fusaric acid resistance protein-like 349 472 1.4E-19 T 14-10-2018 MB46_09580 104ee60b0870314024b255c06d897604 80 SUPERFAMILY SSF54814 16 61 3.14E-7 T 14-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 MB46_09580 104ee60b0870314024b255c06d897604 80 Gene3D G3DSA:3.30.300.20 2 79 3.4E-7 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta MB46_09580 104ee60b0870314024b255c06d897604 80 Hamap MF_00088 UPF0109 protein . 2 74 20.838 T 14-10-2018 IPR020627 Uncharacterised protein family UPF0109 MB46_09580 104ee60b0870314024b255c06d897604 80 Pfam PF13083 KH domain 4 73 4.8E-22 T 14-10-2018 MB46_09515 0407528b8699bc55505c0cd0d632eb57 118 Hamap MF_00048 UPF0102 protein YraN [yraN]. 4 114 20.161 T 14-10-2018 IPR003509 Uncharacterised protein family UPF0102 MB46_09515 0407528b8699bc55505c0cd0d632eb57 118 SUPERFAMILY SSF52980 11 107 3.65E-20 T 14-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 MB46_09515 0407528b8699bc55505c0cd0d632eb57 118 Pfam PF02021 Uncharacterised protein family UPF0102 11 101 1.0E-26 T 14-10-2018 IPR003509 Uncharacterised protein family UPF0102 MB46_09515 0407528b8699bc55505c0cd0d632eb57 118 Gene3D G3DSA:3.40.1350.10 10 117 6.3E-28 T 14-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 MB46_17310 55df59538a09c043eabed546c28e32fe 317 SUPERFAMILY SSF56300 51 272 1.52E-28 T 14-10-2018 MB46_17310 55df59538a09c043eabed546c28e32fe 317 Pfam PF00149 Calcineurin-like phosphoesterase 57 246 8.3E-9 T 14-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 MB46_17310 55df59538a09c043eabed546c28e32fe 317 Gene3D G3DSA:3.60.21.10 56 276 1.5E-14 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like MB46_13150 ce16c4ba5be104674291f32d8bf4bcdd 201 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 10 134 1.8E-29 T 14-10-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 MB46_13150 ce16c4ba5be104674291f32d8bf4bcdd 201 Gene3D G3DSA:3.40.50.300 3 152 4.5E-32 T 14-10-2018 MB46_13150 ce16c4ba5be104674291f32d8bf4bcdd 201 SUPERFAMILY SSF52540 25 115 1.49E-11 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_13150 ce16c4ba5be104674291f32d8bf4bcdd 201 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 13 135 3.5E-22 T 14-10-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 MB46_05435 19661c5fc70083e07bb5a18bdbb13f41 691 Pfam PF13280 WYL domain 163 333 1.7E-24 T 14-10-2018 IPR026881 WYL domain MB46_05435 19661c5fc70083e07bb5a18bdbb13f41 691 Pfam PF13280 WYL domain 502 669 2.5E-20 T 14-10-2018 IPR026881 WYL domain MB46_15145 2ae51a08abfd9b9974365fd5c5719ba4 204 SUPERFAMILY SSF81296 43 136 3.15E-20 T 14-10-2018 IPR014756 Immunoglobulin E-set MB46_15145 2ae51a08abfd9b9974365fd5c5719ba4 204 Gene3D G3DSA:2.60.40.1220 44 144 1.6E-19 T 14-10-2018 MB46_15145 2ae51a08abfd9b9974365fd5c5719ba4 204 Pfam PF04234 CopC domain 44 136 1.9E-19 T 14-10-2018 IPR007348 CopC domain GO:0005507|GO:0042597|GO:0046688 MB46_11730 58ee13a66dcea32b1fbd1d6db98e3508 234 SUPERFAMILY SSF46785 26 206 1.92E-10 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_11730 58ee13a66dcea32b1fbd1d6db98e3508 234 Gene3D G3DSA:1.10.10.10 20 105 3.9E-8 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_07805 5c7407c869c8309371cd7395df243421 405 Pfam PF12697 Alpha/beta hydrolase family 172 334 2.2E-6 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MB46_07805 5c7407c869c8309371cd7395df243421 405 SUPERFAMILY SSF53474 140 397 4.59E-30 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_07805 5c7407c869c8309371cd7395df243421 405 Gene3D G3DSA:3.40.50.1820 132 397 2.9E-26 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_04350 6a8cc0074a75465c6295b70f8a993285 430 Pfam PF13416 Bacterial extracellular solute-binding protein 59 362 5.4E-41 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein MB46_04350 6a8cc0074a75465c6295b70f8a993285 430 SUPERFAMILY SSF53850 34 427 7.25E-76 T 14-10-2018 MB46_04350 6a8cc0074a75465c6295b70f8a993285 430 Gene3D G3DSA:3.40.190.10 58 384 7.5E-81 T 14-10-2018 MB46_04350 6a8cc0074a75465c6295b70f8a993285 430 Gene3D G3DSA:3.40.190.10 156 421 7.5E-81 T 14-10-2018 MB46_00490 47504c1826ef1e5bd138c38e539a27b1 238 SUPERFAMILY SSF56784 13 225 1.1E-46 T 14-10-2018 IPR036412 HAD-like superfamily MB46_00490 47504c1826ef1e5bd138c38e539a27b1 238 Pfam PF13419 Haloacid dehalogenase-like hydrolase 17 198 4.1E-26 T 14-10-2018 MB46_00490 47504c1826ef1e5bd138c38e539a27b1 238 Gene3D G3DSA:3.40.50.1000 17 209 1.4E-55 T 14-10-2018 IPR023214 HAD superfamily MB46_00490 47504c1826ef1e5bd138c38e539a27b1 238 Gene3D G3DSA:1.10.150.240 28 94 1.4E-55 T 14-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 MB46_10555 e8892d8688b1cc5c51fd852f7fa177b5 278 Gene3D G3DSA:1.10.3720.10 72 266 1.3E-26 T 14-10-2018 IPR035906 MetI-like superfamily MB46_10555 e8892d8688b1cc5c51fd852f7fa177b5 278 SUPERFAMILY SSF161098 74 256 1.05E-29 T 14-10-2018 IPR035906 MetI-like superfamily MB46_10555 e8892d8688b1cc5c51fd852f7fa177b5 278 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 108 253 2.3E-9 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_10555 e8892d8688b1cc5c51fd852f7fa177b5 278 TIGRFAM TIGR01097 PhnE: phosphonate ABC transporter, permease protein PhnE 22 266 1.1E-79 T 14-10-2018 IPR005769 ABC transporter, permease PhnE/PtxC GO:0005887|GO:0015604|GO:0015716 MB46_11235 a702e68b1f5e60ea2864e9a953f50006 171 Pfam PF07681 DoxX 6 90 5.5E-12 T 14-10-2018 IPR032808 DoxX family MB46_04695 a52e73a4871cd441dd7858f201302bce 206 Pfam PF11241 Protein of unknown function (DUF3043) 32 203 8.5E-54 T 14-10-2018 IPR021403 Protein of unknown function DUF3043 MB46_19635 4180d0f2ce8136df1450b5c0d1768c93 338 SUPERFAMILY SSF103481 203 300 1.83E-10 T 14-10-2018 MB46_19635 4180d0f2ce8136df1450b5c0d1768c93 338 SUPERFAMILY SSF103481 50 152 6.8E-6 T 14-10-2018 MB46_19635 4180d0f2ce8136df1450b5c0d1768c93 338 Pfam PF00892 EamA-like transporter family 19 150 1.3E-10 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MB46_19635 4180d0f2ce8136df1450b5c0d1768c93 338 Pfam PF00892 EamA-like transporter family 164 296 7.1E-8 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MB46_18075 333ce48929f116b03d750be7fc7f33ad 222 Gene3D G3DSA:1.10.10.60 131 221 3.8E-11 T 14-10-2018 MB46_18075 333ce48929f116b03d750be7fc7f33ad 222 SMART SM00342 134 216 6.8E-4 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MB46_18075 333ce48929f116b03d750be7fc7f33ad 222 Pfam PF12833 Helix-turn-helix domain 144 215 1.7E-9 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MB46_01120 cf2f6ea48f3b202faa1e171da673b268 364 SUPERFAMILY SSF47240 10 127 5.27E-5 T 14-10-2018 IPR009078 Ferritin-like superfamily MB46_01120 cf2f6ea48f3b202faa1e171da673b268 364 Pfam PF01988 VIT family 139 355 2.2E-56 T 14-10-2018 IPR008217 Ccc1 family MB46_11175 286e115cd0db579e99787b9687b570c3 507 Gene3D G3DSA:3.40.190.10 65 488 3.5E-95 T 14-10-2018 MB46_11175 286e115cd0db579e99787b9687b570c3 507 PIRSF PIRSF002741 3 504 1.3E-71 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 MB46_11175 286e115cd0db579e99787b9687b570c3 507 Gene3D G3DSA:3.10.105.10 269 478 3.5E-95 T 14-10-2018 MB46_11175 286e115cd0db579e99787b9687b570c3 507 SUPERFAMILY SSF53850 34 488 7.24E-94 T 14-10-2018 MB46_11175 286e115cd0db579e99787b9687b570c3 507 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 79 416 1.3E-65 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain MB46_00585 4d489bd3f0f1cd69bffdb032be7447da 88 SUPERFAMILY SSF68912 53 85 6.67E-5 T 14-10-2018 IPR036269 Rho termination factor, N-terminal domain superfamily MB46_00585 4d489bd3f0f1cd69bffdb032be7447da 88 Pfam PF07498 Rho termination factor, N-terminal domain 54 83 2.2E-8 T 14-10-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 MB46_06575 3e2c962a16cafa6b3514e10ca0e94871 332 Pfam PF00892 EamA-like transporter family 150 283 2.7E-17 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MB46_06575 3e2c962a16cafa6b3514e10ca0e94871 332 SUPERFAMILY SSF103481 187 286 2.09E-11 T 14-10-2018 MB46_08635 bb6c07c7184d6d8648edd129f0ce2fa8 493 Pfam PF03993 Domain of Unknown Function (DUF349) 254 326 2.3E-17 T 14-10-2018 IPR007139 Protein of unknown function DUF349 MB46_08635 bb6c07c7184d6d8648edd129f0ce2fa8 493 Pfam PF03993 Domain of Unknown Function (DUF349) 187 240 8.9E-7 T 14-10-2018 IPR007139 Protein of unknown function DUF349 MB46_08635 bb6c07c7184d6d8648edd129f0ce2fa8 493 Pfam PF03993 Domain of Unknown Function (DUF349) 330 403 1.1E-20 T 14-10-2018 IPR007139 Protein of unknown function DUF349 MB46_14075 bbfac96ccd8372f914d8df8b861a5122 128 SMART SM00248 47 76 6.5E-5 T 14-10-2018 IPR002110 Ankyrin repeat GO:0005515 MB46_14075 bbfac96ccd8372f914d8df8b861a5122 128 SMART SM00248 80 109 300.0 T 14-10-2018 IPR002110 Ankyrin repeat GO:0005515 MB46_14075 bbfac96ccd8372f914d8df8b861a5122 128 Pfam PF13857 Ankyrin repeats (many copies) 35 85 5.6E-9 T 14-10-2018 MB46_14075 bbfac96ccd8372f914d8df8b861a5122 128 SUPERFAMILY SSF48403 23 112 4.35E-19 T 14-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily MB46_14075 bbfac96ccd8372f914d8df8b861a5122 128 Gene3D G3DSA:1.25.40.20 3 123 2.3E-22 T 14-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily MB46_08850 3bf37baab7537fdbcf4f74bcbc389b52 325 Gene3D G3DSA:3.20.20.220 8 307 1.8E-90 T 14-10-2018 MB46_08850 3bf37baab7537fdbcf4f74bcbc389b52 325 SUPERFAMILY SSF51730 16 302 2.16E-77 T 14-10-2018 IPR029041 FAD-linked oxidoreductase-like MB46_08850 3bf37baab7537fdbcf4f74bcbc389b52 325 Pfam PF02219 Methylenetetrahydrofolate reductase 18 300 2.6E-73 T 14-10-2018 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 MB46_04080 9131bdb9eade090cad04a0591558be37 184 Gene3D G3DSA:1.10.3300.10 5 177 1.2E-32 T 14-10-2018 IPR023286 ABATE domain superfamily MB46_04080 9131bdb9eade090cad04a0591558be37 184 Pfam PF11706 CGNR zinc finger 129 175 9.4E-13 T 14-10-2018 IPR021005 Zinc finger, CGNR MB46_04080 9131bdb9eade090cad04a0591558be37 184 SUPERFAMILY SSF160904 1 175 1.29E-31 T 14-10-2018 MB46_08170 06fa0bb2bad4a19755dfbe5b05ab4e22 156 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 150 73.738 T 14-10-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 MB46_08170 06fa0bb2bad4a19755dfbe5b05ab4e22 156 Pfam PF03477 ATP cone domain 47 132 1.0E-13 T 14-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 MB46_08170 06fa0bb2bad4a19755dfbe5b05ab4e22 156 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 144 9.7E-46 T 14-10-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 MB46_16530 61e004359482179822234686bfd4df16 139 SUPERFAMILY SSF54637 3 115 3.83E-25 T 14-10-2018 IPR029069 HotDog domain superfamily MB46_16530 61e004359482179822234686bfd4df16 139 Gene3D G3DSA:3.10.129.10 2 118 2.4E-21 T 14-10-2018 MB46_16530 61e004359482179822234686bfd4df16 139 Pfam PF03061 Thioesterase superfamily 17 88 1.0E-14 T 14-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 MB46_07580 a72fa6a207432700272714b878ed4a5d 103 Pfam PF01527 Transposase 3 82 1.2E-6 T 14-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 MB46_07580 a72fa6a207432700272714b878ed4a5d 103 SUPERFAMILY SSF46689 1 97 1.91E-15 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MB46_07580 a72fa6a207432700272714b878ed4a5d 103 Gene3D G3DSA:1.10.10.10 1 63 7.1E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_09925 6c0219ac9cc9291830599143da545393 267 SUPERFAMILY SSF69593 17 232 3.01E-45 T 14-10-2018 MB46_09925 6c0219ac9cc9291830599143da545393 267 SMART SM00563 40 158 1.1E-31 T 14-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 MB46_09925 6c0219ac9cc9291830599143da545393 267 Pfam PF01553 Acyltransferase 30 155 5.0E-23 T 14-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 MB46_08935 6b2c26fe5daa1d2e71890ab2161f852c 205 Pfam PF01467 Cytidylyltransferase-like 2 158 5.4E-29 T 14-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 MB46_08935 6b2c26fe5daa1d2e71890ab2161f852c 205 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 1 184 26.0 T 14-10-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 MB46_08935 6b2c26fe5daa1d2e71890ab2161f852c 205 Gene3D G3DSA:3.40.50.620 1 191 4.0E-56 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MB46_08935 6b2c26fe5daa1d2e71890ab2161f852c 205 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 2 61 5.2E-9 T 14-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 MB46_08935 6b2c26fe5daa1d2e71890ab2161f852c 205 SUPERFAMILY SSF52374 1 187 7.51E-48 T 14-10-2018 MB46_08935 6b2c26fe5daa1d2e71890ab2161f852c 205 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 1 183 2.5E-51 T 14-10-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 MB46_14485 e1def342fd89f3c09ea83608e713a951 198 Pfam PF13302 Acetyltransferase (GNAT) domain 12 161 2.5E-27 T 14-10-2018 IPR000182 GNAT domain MB46_14485 e1def342fd89f3c09ea83608e713a951 198 Gene3D G3DSA:3.40.630.30 4 196 1.2E-42 T 14-10-2018 MB46_14485 e1def342fd89f3c09ea83608e713a951 198 SUPERFAMILY SSF55729 5 185 3.73E-42 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase MB46_03285 7a8e93a2208d1060185344350d9070da 249 Pfam PF00005 ABC transporter 30 167 3.0E-6 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_03285 7a8e93a2208d1060185344350d9070da 249 SUPERFAMILY SSF52540 3 197 9.46E-16 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_03285 7a8e93a2208d1060185344350d9070da 249 Gene3D G3DSA:3.40.50.300 1 234 5.1E-16 T 14-10-2018 MB46_12240 dd1872ce1aca63cc93942b9373fa2ba5 338 Pfam PF16881 N-terminal domain of lipoyl synthase of Radical_SAM family 24 60 2.2E-7 T 14-10-2018 IPR031691 Lipoyl synthase, N-terminal KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 MB46_12240 dd1872ce1aca63cc93942b9373fa2ba5 338 SUPERFAMILY SSF102114 43 309 7.72E-57 T 14-10-2018 MB46_12240 dd1872ce1aca63cc93942b9373fa2ba5 338 Pfam PF04055 Radical SAM superfamily 81 235 1.8E-9 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MB46_12240 dd1872ce1aca63cc93942b9373fa2ba5 338 PIRSF PIRSF005963 4 319 1.0E-120 T 14-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 MB46_12240 dd1872ce1aca63cc93942b9373fa2ba5 338 Gene3D G3DSA:3.20.20.70 74 279 2.6E-14 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MB46_12240 dd1872ce1aca63cc93942b9373fa2ba5 338 TIGRFAM TIGR00510 lipA: lipoyl synthase 22 306 2.8E-101 T 14-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 MB46_12240 dd1872ce1aca63cc93942b9373fa2ba5 338 Hamap MF_00206 Lipoyl synthase [lipA]. 1 307 133.149 T 14-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 MB46_12240 dd1872ce1aca63cc93942b9373fa2ba5 338 SMART SM00729 71 277 8.3E-11 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 MB46_03165 a3ea7e42d989648171cd4fd0ea2af6be 528 Pfam PF03239 Iron permease FTR1 family 2 251 3.0E-45 T 14-10-2018 IPR004923 Iron permease FTR1/Fip1/EfeU GO:0005381|GO:0016020|GO:0033573|GO:0034755 MB46_03530 d19bde7832426a8974aaa0750f0371a8 241 Gene3D G3DSA:3.40.50.2300 1 129 6.2E-29 T 14-10-2018 MB46_03530 d19bde7832426a8974aaa0750f0371a8 241 SUPERFAMILY SSF52172 1 122 1.99E-28 T 14-10-2018 IPR011006 CheY-like superfamily MB46_03530 d19bde7832426a8974aaa0750f0371a8 241 SMART SM00850 138 233 1.1E-23 T 14-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 MB46_03530 d19bde7832426a8974aaa0750f0371a8 241 Pfam PF00072 Response regulator receiver domain 4 113 4.2E-21 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MB46_03530 d19bde7832426a8974aaa0750f0371a8 241 Gene3D G3DSA:2.40.50.40 130 197 3.1E-10 T 14-10-2018 MB46_03530 d19bde7832426a8974aaa0750f0371a8 241 Pfam PF04397 LytTr DNA-binding domain 142 232 4.9E-19 T 14-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 MB46_03530 d19bde7832426a8974aaa0750f0371a8 241 SMART SM00448 2 113 4.2E-21 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MB46_07810 f836d20833d5a926472d6ef8200d88fc 163 SUPERFAMILY SSF52402 4 154 5.72E-28 T 14-10-2018 MB46_18610 e2c74dae7af860b19812f57a83e0d2bb 279 Pfam PF00899 ThiF family 46 258 2.6E-48 T 14-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 MB46_18610 e2c74dae7af860b19812f57a83e0d2bb 279 Gene3D G3DSA:3.40.50.720 23 277 2.2E-61 T 14-10-2018 MB46_18610 e2c74dae7af860b19812f57a83e0d2bb 279 SUPERFAMILY SSF69572 13 264 7.85E-61 T 14-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 MB46_01960 4cfc8b50f01fdee6353956d28cc63197 431 Pfam PF02653 Branched-chain amino acid transport system / permease component 135 410 9.6E-38 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 MB46_18380 6810a23762c86497bde7ca663bd66f86 238 SUPERFAMILY SSF55961 5 118 1.14E-10 T 14-10-2018 MB46_18380 6810a23762c86497bde7ca663bd66f86 238 Gene3D G3DSA:3.30.530.20 1 137 3.2E-8 T 14-10-2018 IPR023393 START-like domain superfamily MB46_08205 90941363e97a70305191ab22862138a1 96 Pfam PF02325 YGGT family 10 86 3.2E-10 T 14-10-2018 IPR003425 CCB3/YggT GO:0016020 MB46_07110 06cbe7a0790bf989011793613098d9e4 129 Pfam PF04237 YjbR 16 106 1.7E-24 T 14-10-2018 IPR007351 Uncharacterised protein YjbR MB46_07110 06cbe7a0790bf989011793613098d9e4 129 Gene3D G3DSA:3.90.1150.30 2 123 4.7E-38 T 14-10-2018 IPR038056 YjbR-like superfamily MB46_07110 06cbe7a0790bf989011793613098d9e4 129 SUPERFAMILY SSF142906 9 116 2.49E-33 T 14-10-2018 IPR038056 YjbR-like superfamily MB46_13295 8891d7bbd612ee67cfc204f650d7fa0a 37 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 1 37 2.0E-22 T 14-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_13295 8891d7bbd612ee67cfc204f650d7fa0a 37 ProDom PD002101 RIBOSOMAL L36 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID B SUBUNIT DIRECT SEQUENCING 9 37 2.0E-9 T 14-10-2018 MB46_13295 8891d7bbd612ee67cfc204f650d7fa0a 37 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 37 17.945 T 14-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_13295 8891d7bbd612ee67cfc204f650d7fa0a 37 Pfam PF00444 Ribosomal protein L36 1 37 1.5E-19 T 14-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_13295 8891d7bbd612ee67cfc204f650d7fa0a 37 SUPERFAMILY SSF57840 1 37 1.57E-17 T 14-10-2018 IPR035977 Ribosomal protein L36 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_13295 8891d7bbd612ee67cfc204f650d7fa0a 37 ProSitePatterns PS00828 Ribosomal protein L36 signature. 11 36 - T 14-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_13065 4c37deb1f018421962334323af0a323d 339 SUPERFAMILY SSF81345 18 335 2.22E-49 T 14-10-2018 IPR037294 ABC transporter, BtuC-like MB46_13065 4c37deb1f018421962334323af0a323d 339 Pfam PF01032 FecCD transport family 28 335 9.4E-43 T 14-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 MB46_13065 4c37deb1f018421962334323af0a323d 339 Gene3D G3DSA:1.10.3470.10 18 338 9.4E-48 T 14-10-2018 IPR037294 ABC transporter, BtuC-like MB46_09470 4aea536471e15a490ba9f8aca397b444 419 Gene3D G3DSA:1.10.10.2840 282 408 3.2E-39 T 14-10-2018 MB46_09470 4aea536471e15a490ba9f8aca397b444 419 Pfam PF13556 PucR C-terminal helix-turn-helix domain 345 401 1.8E-17 T 14-10-2018 IPR025736 PucR C-terminal helix-turn-helix domain MB46_06170 5a29381d39f4a9455334501649aa3faf 251 SUPERFAMILY SSF69118 12 247 1.99E-57 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MB46_06170 5a29381d39f4a9455334501649aa3faf 251 Gene3D G3DSA:1.20.1290.10 17 250 1.5E-61 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MB46_06170 5a29381d39f4a9455334501649aa3faf 251 Pfam PF02627 Carboxymuconolactone decarboxylase family 27 106 3.7E-11 T 14-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 MB46_06170 5a29381d39f4a9455334501649aa3faf 251 Pfam PF02627 Carboxymuconolactone decarboxylase family 163 246 1.9E-12 T 14-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 MB46_02420 4beef41673169571655dd2c1543afb67 292 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 60 87 - T 14-10-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 MB46_02420 4beef41673169571655dd2c1543afb67 292 SUPERFAMILY SSF53335 28 287 8.81E-61 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MB46_02420 4beef41673169571655dd2c1543afb67 292 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 28 288 47.016 T 14-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 MB46_02420 4beef41673169571655dd2c1543afb67 292 Gene3D G3DSA:1.10.8.100 225 288 2.7E-16 T 14-10-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 MB46_02420 4beef41673169571655dd2c1543afb67 292 SMART SM00650 44 217 2.2E-61 T 14-10-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 MB46_02420 4beef41673169571655dd2c1543afb67 292 Pfam PF00398 Ribosomal RNA adenine dimethylase 32 255 9.4E-40 T 14-10-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm MB46_02420 4beef41673169571655dd2c1543afb67 292 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 28 285 4.1E-69 T 14-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 MB46_02420 4beef41673169571655dd2c1543afb67 292 Gene3D G3DSA:3.40.50.150 7 221 1.9E-55 T 14-10-2018 MB46_04955 0cbe2e6d578f74070465543ebc33c312 236 SUPERFAMILY SSF54211 16 149 2.31E-34 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MB46_04955 0cbe2e6d578f74070465543ebc33c312 236 Gene3D G3DSA:3.30.230.30 8 152 6.0E-48 T 14-10-2018 IPR036956 Impact, N-terminal domain superfamily MB46_04955 0cbe2e6d578f74070465543ebc33c312 236 Pfam PF01205 Uncharacterized protein family UPF0029 25 143 8.6E-25 T 14-10-2018 IPR001498 Impact, N-terminal MB46_17585 8c4d02a48f60f8d838790496f9bac0ec 119 Gene3D G3DSA:3.30.70.100 1 96 1.2E-24 T 14-10-2018 MB46_17585 8c4d02a48f60f8d838790496f9bac0ec 119 SUPERFAMILY SSF54909 1 104 3.49E-24 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel MB46_17585 8c4d02a48f60f8d838790496f9bac0ec 119 Pfam PF05336 L-rhamnose mutarotase 2 103 1.8E-23 T 14-10-2018 IPR008000 Rhamnose/fucose mutarotase GO:0005737|GO:0016857 MB46_05110 84de401daf673af43a4fc7e45f849dee 323 Gene3D G3DSA:1.10.357.140 40 195 4.3E-20 T 14-10-2018 MB46_05110 84de401daf673af43a4fc7e45f849dee 323 Pfam PF01040 UbiA prenyltransferase family 47 296 2.0E-61 T 14-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 MB46_05110 84de401daf673af43a4fc7e45f849dee 323 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 29 314 2.1E-93 T 14-10-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 MB46_05110 84de401daf673af43a4fc7e45f849dee 323 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 26 316 19.098 T 14-10-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 MB46_05110 84de401daf673af43a4fc7e45f849dee 323 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 86 108 - T 14-10-2018 IPR030470 UbiA prenyltransferase conserved site MB46_02750 bff5e901e58604189302f3b69774568a 124 SUPERFAMILY SSF50022 20 124 2.88E-31 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 MB46_02750 bff5e901e58604189302f3b69774568a 124 Gene3D G3DSA:2.102.10.10 16 124 1.3E-33 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 MB46_02750 bff5e901e58604189302f3b69774568a 124 TIGRFAM TIGR02378 nirD_assim_sml: nitrite reductase [NAD(P)H], small subunit 20 123 1.8E-27 T 14-10-2018 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 MB46_02750 bff5e901e58604189302f3b69774568a 124 Pfam PF13806 Rieske-like [2Fe-2S] domain 20 123 2.4E-33 T 14-10-2018 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 MB46_04110 28355b87a145750fe4244d7d9fec6895 456 SUPERFAMILY SSF63737 19 211 2.88E-37 T 14-10-2018 MB46_04110 28355b87a145750fe4244d7d9fec6895 456 Gene3D G3DSA:1.10.390.60 221 448 2.4E-35 T 14-10-2018 MB46_04110 28355b87a145750fe4244d7d9fec6895 456 Gene3D G3DSA:2.60.40.1730 28 212 2.9E-30 T 14-10-2018 MB46_04110 28355b87a145750fe4244d7d9fec6895 456 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 148 163 7.4E-14 T 14-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 MB46_04110 28355b87a145750fe4244d7d9fec6895 456 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 195 210 7.4E-14 T 14-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 MB46_04110 28355b87a145750fe4244d7d9fec6895 456 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 302 317 7.4E-14 T 14-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 MB46_04110 28355b87a145750fe4244d7d9fec6895 456 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 321 333 7.4E-14 T 14-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 MB46_04110 28355b87a145750fe4244d7d9fec6895 456 SUPERFAMILY SSF55486 226 453 9.23E-50 T 14-10-2018 MB46_04110 28355b87a145750fe4244d7d9fec6895 456 Pfam PF01433 Peptidase family M1 domain 229 425 4.8E-26 T 14-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 MB46_04510 e2b5528a5a1ac764221968f14b39287f 352 Pfam PF01494 FAD binding domain 127 311 1.9E-7 T 14-10-2018 IPR002938 FAD-binding domain GO:0071949 MB46_04510 e2b5528a5a1ac764221968f14b39287f 352 SUPERFAMILY SSF51905 5 325 5.74E-41 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_04510 e2b5528a5a1ac764221968f14b39287f 352 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 250 265 3.0E-10 T 14-10-2018 MB46_04510 e2b5528a5a1ac764221968f14b39287f 352 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 265 281 3.0E-10 T 14-10-2018 MB46_04510 e2b5528a5a1ac764221968f14b39287f 352 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 3.0E-10 T 14-10-2018 MB46_04510 e2b5528a5a1ac764221968f14b39287f 352 Pfam PF13450 NAD(P)-binding Rossmann-like domain 7 36 1.8E-5 T 14-10-2018 MB46_04510 e2b5528a5a1ac764221968f14b39287f 352 Gene3D G3DSA:3.50.50.60 4 332 1.5E-60 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_17360 eadebd123b16385d454c30d1cb92b67e 440 Gene3D G3DSA:3.40.190.10 169 421 4.0E-129 T 14-10-2018 MB46_17360 eadebd123b16385d454c30d1cb92b67e 440 Gene3D G3DSA:3.40.190.10 72 384 4.0E-129 T 14-10-2018 MB46_17360 eadebd123b16385d454c30d1cb92b67e 440 Pfam PF13416 Bacterial extracellular solute-binding protein 76 360 1.0E-27 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein MB46_17360 eadebd123b16385d454c30d1cb92b67e 440 SUPERFAMILY SSF53850 40 436 1.04E-57 T 14-10-2018 MB46_19665 247ee1c43480451b2673acbe55969db5 161 SUPERFAMILY SSF52540 4 160 8.88E-11 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_19665 247ee1c43480451b2673acbe55969db5 161 Gene3D G3DSA:3.40.50.300 2 159 1.0E-20 T 14-10-2018 MB46_14425 f1fd11f196b6d436501eefea57b18a29 176 Pfam PF01883 Iron-sulfur cluster assembly protein 21 74 6.2E-9 T 14-10-2018 IPR002744 MIP18 family-like MB46_14425 f1fd11f196b6d436501eefea57b18a29 176 SUPERFAMILY SSF117916 10 109 1.28E-20 T 14-10-2018 IPR034904 Fe-S cluster assembly domain superfamily MB46_14425 f1fd11f196b6d436501eefea57b18a29 176 Gene3D G3DSA:3.30.300.130 5 111 2.0E-21 T 14-10-2018 IPR034904 Fe-S cluster assembly domain superfamily MB46_14425 f1fd11f196b6d436501eefea57b18a29 176 TIGRFAM TIGR02159 PA_CoA_Oxy4: phenylacetate-CoA oxygenase, PaaJ subunit 22 175 9.7E-55 T 14-10-2018 IPR011883 Phenylacetate-CoA oxygenase, PaaJ subunit MB46_15310 1cd3eee1e3897d236fe93a4bc70d4621 205 Gene3D G3DSA:1.20.58.220 13 205 7.1E-23 T 14-10-2018 IPR038078 PhoU-like domain superfamily MB46_09980 279ac3c1fe10684870b7aef8ef75bea5 499 SUPERFAMILY SSF48163 329 496 1.44E-34 T 14-10-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 MB46_09980 279ac3c1fe10684870b7aef8ef75bea5 499 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 16 495 6.3E-129 T 14-10-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 MB46_09980 279ac3c1fe10684870b7aef8ef75bea5 499 Gene3D G3DSA:3.40.50.620 16 257 3.0E-88 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MB46_09980 279ac3c1fe10684870b7aef8ef75bea5 499 Gene3D G3DSA:3.90.800.10 85 204 3.0E-88 T 14-10-2018 MB46_09980 279ac3c1fe10684870b7aef8ef75bea5 499 Hamap MF_00022 Glutamate--tRNA ligase [gltX]. 15 498 30.025 T 14-10-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 MB46_09980 279ac3c1fe10684870b7aef8ef75bea5 499 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 16 332 7.6E-80 T 14-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 MB46_09980 279ac3c1fe10684870b7aef8ef75bea5 499 SUPERFAMILY SSF52374 16 327 3.75E-96 T 14-10-2018 MB46_09980 279ac3c1fe10684870b7aef8ef75bea5 499 PRINTS PR00987 Glutamyl-tRNA synthetase signature 33 44 1.2E-22 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 MB46_09980 279ac3c1fe10684870b7aef8ef75bea5 499 PRINTS PR00987 Glutamyl-tRNA synthetase signature 48 61 1.2E-22 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 MB46_09980 279ac3c1fe10684870b7aef8ef75bea5 499 PRINTS PR00987 Glutamyl-tRNA synthetase signature 219 227 1.2E-22 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 MB46_09980 279ac3c1fe10684870b7aef8ef75bea5 499 PRINTS PR00987 Glutamyl-tRNA synthetase signature 203 213 1.2E-22 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 MB46_09980 279ac3c1fe10684870b7aef8ef75bea5 499 PRINTS PR00987 Glutamyl-tRNA synthetase signature 19 31 1.2E-22 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 MB46_09980 279ac3c1fe10684870b7aef8ef75bea5 499 Gene3D G3DSA:1.10.1160.10 261 344 1.6E-25 T 14-10-2018 IPR020061 Glutamine-tRNA ligase, alpha-bundle domain superfamily GO:0005524 MB46_09980 279ac3c1fe10684870b7aef8ef75bea5 499 Gene3D G3DSA:1.10.10.350 403 499 1.7E-24 T 14-10-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 MB46_14230 5f08559bcc9093ff70035992fdf89cbb 216 TIGRFAM TIGR01528 NMN_trans_PnuC: nicotinamide mononucleotide transporter PnuC 20 203 1.2E-26 T 14-10-2018 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 MB46_14230 5f08559bcc9093ff70035992fdf89cbb 216 Pfam PF04973 Nicotinamide mononucleotide transporter 20 202 7.9E-55 T 14-10-2018 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 MB46_00660 f65d4764b2d5e0db9c0ff6707fb3896f 265 SMART SM00014 124 238 0.0013 T 14-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MB46_00660 f65d4764b2d5e0db9c0ff6707fb3896f 265 Pfam PF01569 PAP2 superfamily 125 243 1.6E-17 T 14-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MB46_00660 f65d4764b2d5e0db9c0ff6707fb3896f 265 SUPERFAMILY SSF48317 41 240 3.79E-23 T 14-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily MB46_00660 f65d4764b2d5e0db9c0ff6707fb3896f 265 Gene3D G3DSA:1.20.144.10 154 251 6.0E-14 T 14-10-2018 MB46_10625 3502fbb9c605344eafa747e986630ea9 359 SUPERFAMILY SSF81345 30 351 1.83E-61 T 14-10-2018 IPR037294 ABC transporter, BtuC-like MB46_10625 3502fbb9c605344eafa747e986630ea9 359 Gene3D G3DSA:1.10.3470.10 34 358 3.5E-74 T 14-10-2018 IPR037294 ABC transporter, BtuC-like MB46_10625 3502fbb9c605344eafa747e986630ea9 359 Pfam PF01032 FecCD transport family 48 352 3.8E-69 T 14-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 MB46_02995 38cc5643280cd455a259edb6cb337b6a 310 Gene3D G3DSA:1.10.3720.10 70 309 2.1E-56 T 14-10-2018 IPR035906 MetI-like superfamily MB46_02995 38cc5643280cd455a259edb6cb337b6a 310 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 105 297 3.1E-17 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_02995 38cc5643280cd455a259edb6cb337b6a 310 SUPERFAMILY SSF161098 73 298 1.7E-49 T 14-10-2018 IPR035906 MetI-like superfamily MB46_07280 131e44713da6517d71667d92ba4736a5 190 Pfam PF13302 Acetyltransferase (GNAT) domain 7 150 5.2E-23 T 14-10-2018 IPR000182 GNAT domain MB46_07280 131e44713da6517d71667d92ba4736a5 190 SUPERFAMILY SSF55729 2 170 2.13E-33 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase MB46_07280 131e44713da6517d71667d92ba4736a5 190 Gene3D G3DSA:3.40.630.30 1 181 2.9E-34 T 14-10-2018 MB46_01000 6e0e381506413743935aaa98643e9111 324 Pfam PF12804 MobA-like NTP transferase domain 3 171 6.0E-25 T 14-10-2018 IPR025877 MobA-like NTP transferase MB46_01000 6e0e381506413743935aaa98643e9111 324 SUPERFAMILY SSF53448 2 204 5.63E-18 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MB46_01000 6e0e381506413743935aaa98643e9111 324 Gene3D G3DSA:3.90.550.10 1 209 2.5E-33 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MB46_14935 51b61df5b6425cc51ec26dc509bbb226 141 Pfam PF11349 Protein of unknown function (DUF3151) 11 135 1.2E-54 T 14-10-2018 IPR014487 Protein of unknown function DUF3151 MB46_14935 51b61df5b6425cc51ec26dc509bbb226 141 PIRSF PIRSF017349 4 139 5.1E-51 T 14-10-2018 IPR014487 Protein of unknown function DUF3151 MB46_04325 30f36c137925cb302d48128155517a25 322 Gene3D G3DSA:3.40.960.10 219 318 2.3E-10 T 14-10-2018 MB46_04325 30f36c137925cb302d48128155517a25 322 Pfam PF13338 Transcriptional regulator, AbiEi antitoxin 20 54 1.9E-6 T 14-10-2018 IPR025159 Transcriptional regulator, AbiEi antitoxin MB46_00470 4a7ab630ae1a5ff71e7b63f0ad47c790 157 SUPERFAMILY SSF46785 2 126 3.95E-26 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_00470 4a7ab630ae1a5ff71e7b63f0ad47c790 157 Pfam PF01638 HxlR-like helix-turn-helix 16 105 4.7E-17 T 14-10-2018 IPR002577 Helix-turn-helix, HxlR type MB46_00470 4a7ab630ae1a5ff71e7b63f0ad47c790 157 Gene3D G3DSA:1.10.10.10 2 154 2.2E-34 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_03470 1e7d49bd6461c7c7049f98659e6c8e86 1001 TIGRFAM TIGR01760 tape_meas_TP901: phage tail tape measure protein, TP901 family, core region 63 415 2.9E-39 T 14-10-2018 IPR010090 Phage tail tape measure protein MB46_03470 1e7d49bd6461c7c7049f98659e6c8e86 1001 Pfam PF10145 Phage-related minor tail protein 103 296 4.0E-14 T 14-10-2018 IPR010090 Phage tail tape measure protein MB46_07570 4839d7f4dc45e5385a5170c1ae8436b3 102 Gene3D G3DSA:3.40.50.300 1 69 1.4E-10 T 14-10-2018 MB46_07570 4839d7f4dc45e5385a5170c1ae8436b3 102 Pfam PF01695 IstB-like ATP binding protein 2 55 2.5E-14 T 14-10-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 MB46_12650 9e32f88d918b8480f906c234b3100a93 395 Pfam PF02646 RmuC family 82 371 5.7E-84 T 14-10-2018 IPR003798 DNA recombination RmuC MB46_16520 675b9ff4ce31fa7d41914e0f0f837a52 218 Pfam PF01981 Peptidyl-tRNA hydrolase PTH2 128 210 4.4E-9 T 14-10-2018 IPR002833 Peptidyl-tRNA hydrolase, PTH2 GO:0004045 MetaCyc: PWY-6308 MB46_16520 675b9ff4ce31fa7d41914e0f0f837a52 218 Gene3D G3DSA:3.40.1490.10 127 217 2.6E-13 T 14-10-2018 IPR023476 Peptidyl-tRNA hydrolase II domain superfamily MetaCyc: PWY-6308 MB46_16520 675b9ff4ce31fa7d41914e0f0f837a52 218 SUPERFAMILY SSF102462 128 212 1.92E-13 T 14-10-2018 IPR023476 Peptidyl-tRNA hydrolase II domain superfamily MetaCyc: PWY-6308 MB46_13670 a8e2f138b77cb527be143da4b974d55f 136 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 78 4.5E-16 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MB46_13670 a8e2f138b77cb527be143da4b974d55f 136 SMART SM00345 19 78 1.6E-12 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MB46_13670 a8e2f138b77cb527be143da4b974d55f 136 SUPERFAMILY SSF46785 8 82 1.99E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_13670 a8e2f138b77cb527be143da4b974d55f 136 Gene3D G3DSA:1.10.10.10 11 135 1.2E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_17830 981f6f8016e895e65f18e1d775200a02 408 Gene3D G3DSA:3.40.190.10 66 370 2.6E-80 T 14-10-2018 MB46_17830 981f6f8016e895e65f18e1d775200a02 408 Pfam PF13416 Bacterial extracellular solute-binding protein 58 356 5.2E-41 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein MB46_17830 981f6f8016e895e65f18e1d775200a02 408 Gene3D G3DSA:3.40.190.10 150 401 2.6E-80 T 14-10-2018 MB46_17830 981f6f8016e895e65f18e1d775200a02 408 SUPERFAMILY SSF53850 40 407 3.37E-73 T 14-10-2018 MB46_14330 db1524801ddf3e1be2ac34025d0ce74a 293 Pfam PF00775 Dioxygenase 127 202 4.8E-11 T 14-10-2018 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 MB46_14330 db1524801ddf3e1be2ac34025d0ce74a 293 Gene3D G3DSA:2.60.130.10 51 264 1.5E-35 T 14-10-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 MB46_14330 db1524801ddf3e1be2ac34025d0ce74a 293 SUPERFAMILY SSF49482 71 272 2.35E-40 T 14-10-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 MB46_01705 068dbc06845f98c8e380040319e6e784 452 SUPERFAMILY SSF103473 13 431 2.62E-27 T 14-10-2018 IPR036259 MFS transporter superfamily MB46_01705 068dbc06845f98c8e380040319e6e784 452 Gene3D G3DSA:1.20.1250.20 8 393 3.5E-27 T 14-10-2018 MB46_01705 068dbc06845f98c8e380040319e6e784 452 Pfam PF07690 Major Facilitator Superfamily 23 369 1.7E-20 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MB46_03505 274526174e0922a2a9bb4ca9affb06dd 185 Pfam PF01765 Ribosome recycling factor 21 183 1.3E-58 T 14-10-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 MB46_03505 274526174e0922a2a9bb4ca9affb06dd 185 Gene3D G3DSA:3.30.1360.40 31 105 2.3E-64 T 14-10-2018 MB46_03505 274526174e0922a2a9bb4ca9affb06dd 185 SUPERFAMILY SSF55194 3 184 1.28E-65 T 14-10-2018 IPR036191 RRF superfamily Reactome: R-HSA-5419276 MB46_03505 274526174e0922a2a9bb4ca9affb06dd 185 Hamap MF_00040 Ribosome-recycling factor [frr]. 3 185 26.321 T 14-10-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 MB46_03505 274526174e0922a2a9bb4ca9affb06dd 185 TIGRFAM TIGR00496 frr: ribosome recycling factor 10 185 3.8E-63 T 14-10-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 MB46_03505 274526174e0922a2a9bb4ca9affb06dd 185 Gene3D G3DSA:1.10.132.20 12 182 2.3E-64 T 14-10-2018 MB46_01270 b765a3d944117a516c5cd47215e40c0c 228 Pfam PF03358 NADPH-dependent FMN reductase 5 154 5.7E-32 T 14-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 MB46_01270 b765a3d944117a516c5cd47215e40c0c 228 Gene3D G3DSA:3.40.50.360 1 182 2.6E-46 T 14-10-2018 IPR029039 Flavoprotein-like superfamily MB46_01270 b765a3d944117a516c5cd47215e40c0c 228 SUPERFAMILY SSF52218 4 158 1.92E-23 T 14-10-2018 IPR029039 Flavoprotein-like superfamily MB46_01270 b765a3d944117a516c5cd47215e40c0c 228 TIGRFAM TIGR04037 LLM_duo_CE1759: LLM-partnered FMN reductase, CE1759 family 5 222 8.9E-78 T 14-10-2018 IPR023932 Uncharacterised protein family, CE1759 MB46_06800 4ec45a6a690f476cc22e6429a915c6ff 60 Pfam PF06769 YoeB-like toxin of bacterial type II toxin-antitoxin system 8 52 3.1E-10 T 14-10-2018 IPR009614 Toxin YoeB GO:0004519|GO:0006401 MB46_06800 4ec45a6a690f476cc22e6429a915c6ff 60 Gene3D G3DSA:3.30.2310.20 5 57 3.1E-9 T 14-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily MB46_01335 6b51713356eaf0b46b8befe5149574c0 185 TIGRFAM TIGR02150 IPP_isom_1: isopentenyl-diphosphate delta-isomerase 10 169 4.0E-43 T 14-10-2018 IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 GO:0004452|GO:0008299 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922|Reactome: R-HSA-191273 MB46_01335 6b51713356eaf0b46b8befe5149574c0 185 Gene3D G3DSA:3.90.79.10 4 174 4.9E-49 T 14-10-2018 MB46_01335 6b51713356eaf0b46b8befe5149574c0 185 PIRSF PIRSF018427 2 177 3.8E-51 T 14-10-2018 IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 GO:0004452|GO:0008299 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922|Reactome: R-HSA-191273 MB46_01335 6b51713356eaf0b46b8befe5149574c0 185 Hamap MF_00202 Isopentenyl-diphosphate Delta-isomerase [idi]. 6 181 34.298 T 14-10-2018 IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 GO:0004452|GO:0008299 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922|Reactome: R-HSA-191273 MB46_01335 6b51713356eaf0b46b8befe5149574c0 185 SUPERFAMILY SSF55811 6 170 1.62E-44 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 MB46_01335 6b51713356eaf0b46b8befe5149574c0 185 Pfam PF00293 NUDIX domain 33 165 4.3E-16 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MB46_02990 1f5e3171e6962365e4bdf1f10461349f 297 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 106 287 4.3E-24 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_02990 1f5e3171e6962365e4bdf1f10461349f 297 SUPERFAMILY SSF161098 25 297 2.71E-64 T 14-10-2018 IPR035906 MetI-like superfamily MB46_02990 1f5e3171e6962365e4bdf1f10461349f 297 Gene3D G3DSA:1.10.3720.10 23 285 2.9E-57 T 14-10-2018 IPR035906 MetI-like superfamily MB46_14090 020eb28244217e1ee48285fddecc5f07 211 Pfam PF09365 Conserved hypothetical protein (DUF2461) 11 204 4.1E-43 T 14-10-2018 IPR012808 Conserved hypothetical protein CHP02453 MB46_14090 020eb28244217e1ee48285fddecc5f07 211 TIGRFAM TIGR02453 TIGR02453: TIGR02453 family protein 10 206 5.9E-38 T 14-10-2018 IPR012808 Conserved hypothetical protein CHP02453 MB46_14090 020eb28244217e1ee48285fddecc5f07 211 PIRSF PIRSF028451 3 210 8.7E-33 T 14-10-2018 IPR015996 Uncharacterised conserved protein UCP028451 MB46_13510 2aed93bd167af399ed77b825f6504ee3 187 SUPERFAMILY SSF55729 3 180 4.96E-23 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase MB46_13510 2aed93bd167af399ed77b825f6504ee3 187 Gene3D G3DSA:3.40.630.30 1 181 7.9E-33 T 14-10-2018 MB46_13510 2aed93bd167af399ed77b825f6504ee3 187 Pfam PF00583 Acetyltransferase (GNAT) family 47 157 9.2E-10 T 14-10-2018 IPR000182 GNAT domain MB46_16655 0331798cbea107f1c81177da0c4ac1b7 168 SUPERFAMILY SSF89562 14 167 3.66E-44 T 14-10-2018 IPR036704 Ribonuclease E inhibitor RraA/RraA-like superfamily MB46_16655 0331798cbea107f1c81177da0c4ac1b7 168 TIGRFAM TIGR01935 NOT-MenG: RraA family 16 165 2.9E-56 T 14-10-2018 IPR010203 Regulator of ribonuclease activity A GO:0008428|GO:0051252 MB46_16655 0331798cbea107f1c81177da0c4ac1b7 168 Pfam PF03737 Aldolase/RraA 16 164 2.1E-41 T 14-10-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein MB46_16655 0331798cbea107f1c81177da0c4ac1b7 168 Gene3D G3DSA:3.50.30.40 10 168 1.5E-57 T 14-10-2018 MB46_12300 41ff467dcb8a684b7ab3eba43c0ab7d8 437 PIRSF PIRSF000138 6 409 1.2E-113 T 14-10-2018 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 Reactome: R-HSA-9033241 MB46_12300 41ff467dcb8a684b7ab3eba43c0ab7d8 437 SUPERFAMILY SSF51395 27 398 4.58E-86 T 14-10-2018 MB46_12300 41ff467dcb8a684b7ab3eba43c0ab7d8 437 ProSitePatterns PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. 299 305 - T 14-10-2018 IPR008259 FMN-dependent alpha-hydroxy acid dehydrogenase, active site GO:0016491|GO:0055114 Reactome: R-HSA-9033241 MB46_12300 41ff467dcb8a684b7ab3eba43c0ab7d8 437 Gene3D G3DSA:3.20.20.70 27 405 1.6E-117 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MB46_12300 41ff467dcb8a684b7ab3eba43c0ab7d8 437 Pfam PF01070 FMN-dependent dehydrogenase 37 398 2.4E-115 T 14-10-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 Reactome: R-HSA-9033241 MB46_11225 36429ded625d1ca2582d393dd30b5f43 86 Gene3D G3DSA:1.10.10.1320 15 86 5.7E-5 T 14-10-2018 MB46_11225 36429ded625d1ca2582d393dd30b5f43 86 Pfam PF13490 Putative zinc-finger 17 45 1.4E-8 T 14-10-2018 IPR027383 Putative zinc-finger MB46_11225 36429ded625d1ca2582d393dd30b5f43 86 TIGRFAM TIGR02949 anti_SigH_actin: anti-sigma factor, TIGR02949 family 3 80 3.9E-26 T 14-10-2018 IPR014295 Anti-sigma factor MB46_11225 36429ded625d1ca2582d393dd30b5f43 86 TIGRFAM TIGR03988 antisig_RsrA: mycothiol system anti-sigma-R factor 9 80 1.1E-24 T 14-10-2018 IPR024020 Anti sigma-R factor, mycothiol system,RsrA MB46_09720 d8c1df64dccbc1594d45a811c63ee763 642 Gene3D G3DSA:3.50.50.60 108 259 2.5E-5 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_09720 d8c1df64dccbc1594d45a811c63ee763 642 SUPERFAMILY SSF51905 28 249 2.98E-7 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_09720 d8c1df64dccbc1594d45a811c63ee763 642 Pfam PF13454 FAD-NAD(P)-binding 10 189 2.6E-38 T 14-10-2018 IPR038732 FAD-dependent urate hydroxylase HpyO, FAD/NAD(P)-binding domain MB46_14575 fa8759ac7825b7524c8235679bfe5cab 144 Pfam PF07681 DoxX 11 94 3.7E-21 T 14-10-2018 IPR032808 DoxX family MB46_02880 7d5dceea5534afb8c0eecd652e98035c 75 Pfam PF13822 Acyl-CoA carboxylase epsilon subunit 13 70 1.8E-17 T 14-10-2018 IPR032716 Acyl-CoA carboxylase epsilon subunit MB46_14895 7298868b8c3bdc25e916cee031002719 135 Pfam PF04237 YjbR 13 113 3.1E-24 T 14-10-2018 IPR007351 Uncharacterised protein YjbR MB46_14895 7298868b8c3bdc25e916cee031002719 135 Gene3D G3DSA:3.90.1150.30 2 134 1.3E-39 T 14-10-2018 IPR038056 YjbR-like superfamily MB46_14895 7298868b8c3bdc25e916cee031002719 135 SUPERFAMILY SSF142906 2 127 1.57E-34 T 14-10-2018 IPR038056 YjbR-like superfamily MB46_04670 561945e01d51c9008de39eb249fffa9a 278 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 215 232 - T 14-10-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199|Reactome: R-HSA-4755609 MB46_04670 561945e01d51c9008de39eb249fffa9a 278 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 42 270 38.027 T 14-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 MB46_04670 561945e01d51c9008de39eb249fffa9a 278 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 42 269 5.1E-76 T 14-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 MB46_04670 561945e01d51c9008de39eb249fffa9a 278 SUPERFAMILY SSF64005 42 265 1.44E-83 T 14-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 MB46_04670 561945e01d51c9008de39eb249fffa9a 278 Pfam PF01255 Putative undecaprenyl diphosphate synthase 49 269 2.0E-74 T 14-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 MB46_04670 561945e01d51c9008de39eb249fffa9a 278 Gene3D G3DSA:3.40.1180.10 2 264 3.5E-97 T 14-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 MB46_16585 0ff64f9cc30e7a267f0766736bdc7cbc 197 Pfam PF10646 Sporulation and spore germination 98 190 2.5E-5 T 14-10-2018 IPR019606 GerMN domain MB46_16585 0ff64f9cc30e7a267f0766736bdc7cbc 197 SMART SM00909 105 194 4.6E-4 T 14-10-2018 IPR019606 GerMN domain MB46_03870 6cf4120af11bb19dcd1483fbcaca4b61 262 Gene3D G3DSA:3.40.50.1820 5 258 6.5E-41 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_03870 6cf4120af11bb19dcd1483fbcaca4b61 262 Pfam PF00561 alpha/beta hydrolase fold 23 128 5.4E-19 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MB46_03870 6cf4120af11bb19dcd1483fbcaca4b61 262 PRINTS PR00111 Alpha/beta hydrolase fold signature 109 122 5.2E-5 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MB46_03870 6cf4120af11bb19dcd1483fbcaca4b61 262 PRINTS PR00111 Alpha/beta hydrolase fold signature 206 220 5.2E-5 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MB46_03870 6cf4120af11bb19dcd1483fbcaca4b61 262 PRINTS PR00111 Alpha/beta hydrolase fold signature 95 108 5.2E-5 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MB46_03870 6cf4120af11bb19dcd1483fbcaca4b61 262 PRINTS PR00111 Alpha/beta hydrolase fold signature 49 64 5.2E-5 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MB46_03870 6cf4120af11bb19dcd1483fbcaca4b61 262 SUPERFAMILY SSF53474 8 260 3.52E-41 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_17235 8d555cb0e1d23c0618699dd8609b812f 76 Pfam PF11273 Protein of unknown function (DUF3073) 2 62 3.4E-20 T 14-10-2018 IPR021426 Protein of unknown function DUF3073 MB46_07895 ece87d8ab87e845a52af83ca0fe29f9a 656 Pfam PF13520 Amino acid permease 57 466 2.4E-24 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 MB46_07895 ece87d8ab87e845a52af83ca0fe29f9a 656 Gene3D G3DSA:1.20.1740.10 52 510 1.4E-16 T 14-10-2018 MB46_19495 c3b03b3da1eba9e83a5973400d664ba0 194 Gene3D G3DSA:1.10.260.40 73 119 2.1E-5 T 14-10-2018 MB46_09305 54b761cbd8d8953e2a308f5b84a17942 225 Gene3D G3DSA:1.25.10.90 2 225 7.4E-70 T 14-10-2018 MB46_09305 54b761cbd8d8953e2a308f5b84a17942 225 Pfam PF08713 DNA alkylation repair enzyme 12 225 2.0E-60 T 14-10-2018 IPR014825 DNA alkylation repair enzyme MB46_09305 54b761cbd8d8953e2a308f5b84a17942 225 SUPERFAMILY SSF48371 21 225 8.63E-48 T 14-10-2018 IPR016024 Armadillo-type fold MB46_08000 31f6813821df4b9db759fd41812cb567 316 Gene3D G3DSA:3.30.2010.10 120 197 1.7E-5 T 14-10-2018 MB46_08000 31f6813821df4b9db759fd41812cb567 316 Pfam PF01435 Peptidase family M48 121 198 3.1E-11 T 14-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 MB46_02810 ad0cbe963e420eb2916698eb4b021b8a 254 SUPERFAMILY SSF53335 46 252 2.49E-16 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MB46_02810 ad0cbe963e420eb2916698eb4b021b8a 254 Pfam PF08241 Methyltransferase domain 53 139 2.5E-4 T 14-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 MB46_02810 ad0cbe963e420eb2916698eb4b021b8a 254 Gene3D G3DSA:3.40.50.150 21 188 6.8E-9 T 14-10-2018 MB46_07650 de801a7824eeaee9c425cbce3a6facb0 203 Pfam PF09534 Tryptophan-associated transmembrane protein (Trp_oprn_chp) 24 202 1.6E-36 T 14-10-2018 IPR019051 Trp biosynthesis associated, transmembrane protein, Oprn/Chp MB46_01255 1b0c8f5dd285b6679c5bad1176568490 322 Pfam PF06089 L-asparaginase II 15 316 1.1E-103 T 14-10-2018 IPR010349 L-asparaginase II MB46_19790 5e74d8eb062a0a3b2fd197317999bd8b 803 Gene3D G3DSA:2.60.40.10 438 536 2.6E-10 T 14-10-2018 IPR013783 Immunoglobulin-like fold MB46_19790 5e74d8eb062a0a3b2fd197317999bd8b 803 Gene3D G3DSA:2.60.40.10 248 346 3.5E-13 T 14-10-2018 IPR013783 Immunoglobulin-like fold MB46_19790 5e74d8eb062a0a3b2fd197317999bd8b 803 Gene3D G3DSA:2.60.40.10 537 630 3.6E-6 T 14-10-2018 IPR013783 Immunoglobulin-like fold MB46_19790 5e74d8eb062a0a3b2fd197317999bd8b 803 SUPERFAMILY SSF51306 39 107 3.82E-6 T 14-10-2018 IPR036286 LexA/Signal peptidase-like superfamily MB46_13895 4f00f43e52efc914229f1c0f792bd6e8 196 SUPERFAMILY SSF52540 15 145 1.65E-12 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_13895 4f00f43e52efc914229f1c0f792bd6e8 196 Gene3D G3DSA:3.40.50.300 14 134 6.9E-7 T 14-10-2018 MB46_17430 e13873b26b933d7eba4a047596f82ec4 237 SUPERFAMILY SSF55729 143 222 6.34E-9 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase MB46_17430 e13873b26b933d7eba4a047596f82ec4 237 Gene3D G3DSA:3.40.630.30 84 232 5.2E-8 T 14-10-2018 MB46_02315 eb8ca0d7778c3bae711925d981d8abe1 167 Pfam PF01478 Type IV leader peptidase family 25 136 1.2E-13 T 14-10-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 MB46_02315 eb8ca0d7778c3bae711925d981d8abe1 167 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 101 112 8.4E-7 T 14-10-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial MB46_02315 eb8ca0d7778c3bae711925d981d8abe1 167 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 90 100 8.4E-7 T 14-10-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial MB46_02315 eb8ca0d7778c3bae711925d981d8abe1 167 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 33 50 8.4E-7 T 14-10-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial MB46_02090 f2e52d32067fb8a5c6112135af345c6b 145 Pfam PF14155 Domain of unknown function (DUF4307) 25 139 6.5E-23 T 14-10-2018 IPR025443 Protein of unknown function DUF4307 MB46_12305 4389c880ab2f67275b03f798b9e8a2a2 303 Gene3D G3DSA:3.40.190.10 151 250 2.0E-45 T 14-10-2018 MB46_12305 4389c880ab2f67275b03f798b9e8a2a2 303 SMART SM00062 64 291 3.1E-21 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MB46_12305 4389c880ab2f67275b03f798b9e8a2a2 303 Gene3D G3DSA:3.40.190.10 62 281 2.0E-45 T 14-10-2018 MB46_12305 4389c880ab2f67275b03f798b9e8a2a2 303 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 65 288 2.0E-39 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MB46_12305 4389c880ab2f67275b03f798b9e8a2a2 303 SUPERFAMILY SSF53850 12 289 1.09E-46 T 14-10-2018 MB46_15065 4c12a380d9a95e073252e2251c0cc38b 576 SMART SM00642 20 442 3.2E-124 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MB46_15065 4c12a380d9a95e073252e2251c0cc38b 576 Pfam PF00128 Alpha amylase, catalytic domain 35 413 3.8E-85 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MB46_15065 4c12a380d9a95e073252e2251c0cc38b 576 SUPERFAMILY SSF51445 9 506 4.42E-125 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily MB46_15065 4c12a380d9a95e073252e2251c0cc38b 576 Gene3D G3DSA:3.20.20.80 12 504 1.5E-150 T 14-10-2018 MB46_15065 4c12a380d9a95e073252e2251c0cc38b 576 Gene3D G3DSA:3.90.400.10 112 188 1.5E-150 T 14-10-2018 MB46_03110 4ba1f8a381a45bbda610a6b6f1dc425d 278 Gene3D G3DSA:3.90.1580.10 1 277 1.4E-107 T 14-10-2018 MB46_03110 4ba1f8a381a45bbda610a6b6f1dc425d 278 SUPERFAMILY SSF56436 1 274 2.2E-80 T 14-10-2018 IPR016187 C-type lectin fold MB46_03110 4ba1f8a381a45bbda610a6b6f1dc425d 278 Pfam PF03781 Sulfatase-modifying factor enzyme 1 2 274 8.1E-72 T 14-10-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 MB46_16385 4419e8be9daf2ddd7eb0b7188a4abbf3 350 Pfam PF00892 EamA-like transporter family 23 157 4.2E-15 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MB46_16385 4419e8be9daf2ddd7eb0b7188a4abbf3 350 Pfam PF00892 EamA-like transporter family 169 311 9.5E-14 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MB46_16385 4419e8be9daf2ddd7eb0b7188a4abbf3 350 SUPERFAMILY SSF103481 216 314 2.62E-6 T 14-10-2018 MB46_16385 4419e8be9daf2ddd7eb0b7188a4abbf3 350 SUPERFAMILY SSF103481 65 157 3.27E-11 T 14-10-2018 MB46_09700 6b45fd3d15f8db87ef84573f8975b2da 282 Pfam PF07920 Protein of unknown function (DUF1684) 135 273 4.7E-41 T 14-10-2018 IPR012467 Protein of unknown function DUF1684 MB46_10570 d6fd062fc3c55a42f6b62335dcf9c6a8 282 SUPERFAMILY SSF56529 105 279 2.35E-51 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 MB46_10570 d6fd062fc3c55a42f6b62335dcf9c6a8 282 Gene3D G3DSA:3.90.850.10 86 281 9.1E-54 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 MB46_10570 d6fd062fc3c55a42f6b62335dcf9c6a8 282 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 103 278 3.3E-48 T 14-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 MB46_02300 8e3b96491633586bb4a652194d92e458 109 SUPERFAMILY SSF54909 4 104 1.18E-6 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel MB46_02300 8e3b96491633586bb4a652194d92e458 109 Pfam PF03795 YCII-related domain 6 93 1.0E-5 T 14-10-2018 IPR005545 YCII-related MB46_10465 1fe08dbc67de0e50c6d52823cc486f41 184 Pfam PF09851 Short C-terminal domain 154 181 3.9E-8 T 14-10-2018 IPR018649 SHOCT domain MB46_17815 60ff020f6954a4658a8ea18e8f6aefb1 354 SUPERFAMILY SSF51679 1 341 2.49E-71 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 MB46_17815 60ff020f6954a4658a8ea18e8f6aefb1 354 Gene3D G3DSA:3.20.20.30 1 352 7.1E-81 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 MB46_17815 60ff020f6954a4658a8ea18e8f6aefb1 354 Pfam PF00296 Luciferase-like monooxygenase 1 302 1.6E-44 T 14-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MB46_01155 9f53bf25c47c6f0d8b8334fc86294e66 659 Pfam PF13520 Amino acid permease 53 483 6.7E-11 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 MB46_01155 9f53bf25c47c6f0d8b8334fc86294e66 659 Gene3D G3DSA:1.20.1740.10 57 508 6.7E-11 T 14-10-2018 MB46_15755 8d594d3aabf2e4817d1629a1df0a0041 235 Pfam PF01810 LysE type translocator 15 219 1.4E-20 T 14-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 MB46_01905 ebda342a6dd202017fedba919b1b78fb 328 Pfam PF03631 Virulence factor BrkB 61 319 8.0E-28 T 14-10-2018 IPR017039 Virulence factor BrkB MB46_09600 1d8922e6b45201834d7cd81b18c9611e 168 SUPERFAMILY SSF55729 1 134 2.19E-22 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase MB46_09600 1d8922e6b45201834d7cd81b18c9611e 168 Pfam PF00583 Acetyltransferase (GNAT) family 53 129 2.2E-14 T 14-10-2018 IPR000182 GNAT domain MB46_09600 1d8922e6b45201834d7cd81b18c9611e 168 Gene3D G3DSA:3.40.630.30 1 166 1.8E-22 T 14-10-2018 MB46_08875 66cc923b4cdaf8c9856e54c697cab4ad 293 Pfam PF01882 Protein of unknown function DUF58 37 121 7.3E-19 T 14-10-2018 IPR002881 Domain of unknown function DUF58 MB46_06505 9f9d46710b7c93fc15beef864c5493d7 386 Gene3D G3DSA:1.10.10.2840 260 385 3.4E-15 T 14-10-2018 MB46_06505 9f9d46710b7c93fc15beef864c5493d7 386 Pfam PF13556 PucR C-terminal helix-turn-helix domain 331 383 3.8E-14 T 14-10-2018 IPR025736 PucR C-terminal helix-turn-helix domain MB46_03705 6d1f546bee64fd6a95ee3efbe6ee379c 247 Pfam PF01061 ABC-2 type transporter 3 209 5.8E-34 T 14-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 MB46_03705 6d1f546bee64fd6a95ee3efbe6ee379c 247 PIRSF PIRSF006648 1 247 2.8E-23 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 MB46_09290 9372af41e741b0b3cae41022be4ee237 154 SUPERFAMILY SSF55961 1 151 1.89E-27 T 14-10-2018 MB46_09290 9372af41e741b0b3cae41022be4ee237 154 Gene3D G3DSA:3.30.530.20 1 154 2.0E-23 T 14-10-2018 IPR023393 START-like domain superfamily MB46_09290 9372af41e741b0b3cae41022be4ee237 154 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 4 150 2.3E-24 T 14-10-2018 IPR019587 Polyketide cyclase/dehydrase MB46_10190 6d0a0ff791674c027c47acc47eed7d0d 323 Gene3D G3DSA:3.30.420.40 131 293 1.2E-71 T 14-10-2018 MB46_10190 6d0a0ff791674c027c47acc47eed7d0d 323 Gene3D G3DSA:3.30.420.40 12 300 1.2E-71 T 14-10-2018 MB46_10190 6d0a0ff791674c027c47acc47eed7d0d 323 SUPERFAMILY SSF53067 10 305 2.91E-54 T 14-10-2018 MB46_10190 6d0a0ff791674c027c47acc47eed7d0d 323 ProSitePatterns PS01125 ROK family signature. 142 169 - T 14-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 MB46_10190 6d0a0ff791674c027c47acc47eed7d0d 323 Pfam PF00480 ROK family 11 303 8.7E-54 T 14-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 MB46_11595 9a95be32aed83ce4bb2d1af8976f9085 73 Gene3D G3DSA:1.10.1660.10 1 54 1.8E-7 T 14-10-2018 MB46_11595 9a95be32aed83ce4bb2d1af8976f9085 73 Pfam PF12728 Helix-turn-helix domain 4 55 2.7E-10 T 14-10-2018 MB46_11595 9a95be32aed83ce4bb2d1af8976f9085 73 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 4 52 2.0E-8 T 14-10-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 MB46_05115 acaf9aa047d24acbd25f3850e7b75e5f 331 Pfam PF02628 Cytochrome oxidase assembly protein 88 218 7.5E-17 T 14-10-2018 IPR003780 COX15/CtaA family GO:0006784|GO:0016021|GO:0016627|GO:0055114 Reactome: R-HSA-189451 MB46_05115 acaf9aa047d24acbd25f3850e7b75e5f 331 Pfam PF02628 Cytochrome oxidase assembly protein 40 83 2.0E-8 T 14-10-2018 IPR003780 COX15/CtaA family GO:0006784|GO:0016021|GO:0016627|GO:0055114 Reactome: R-HSA-189451 MB46_17570 8f8894bcd33d3dcc92ce1b57bb76a3fb 431 SUPERFAMILY SSF53850 38 427 5.02E-56 T 14-10-2018 MB46_17570 8f8894bcd33d3dcc92ce1b57bb76a3fb 431 Gene3D G3DSA:3.40.190.10 42 377 2.6E-115 T 14-10-2018 MB46_17570 8f8894bcd33d3dcc92ce1b57bb76a3fb 431 Pfam PF01547 Bacterial extracellular solute-binding protein 53 340 4.1E-29 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein MB46_17570 8f8894bcd33d3dcc92ce1b57bb76a3fb 431 Gene3D G3DSA:3.40.190.10 150 425 2.6E-115 T 14-10-2018 MB46_18880 25e3c7b2f5d537262635b690c29bbb87 322 Gene3D G3DSA:3.40.50.2300 37 320 1.2E-94 T 14-10-2018 MB46_18880 25e3c7b2f5d537262635b690c29bbb87 322 SUPERFAMILY SSF53822 36 313 4.71E-75 T 14-10-2018 IPR028082 Periplasmic binding protein-like I MB46_18880 25e3c7b2f5d537262635b690c29bbb87 322 Gene3D G3DSA:3.40.50.2300 140 274 1.2E-94 T 14-10-2018 MB46_18880 25e3c7b2f5d537262635b690c29bbb87 322 Pfam PF13407 Periplasmic binding protein domain 37 294 1.9E-62 T 14-10-2018 IPR025997 Periplasmic binding protein MB46_16095 2f04cae4b93a1e4d08b42c43ddae0426 45 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 3 45 1.5E-19 T 14-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_16095 2f04cae4b93a1e4d08b42c43ddae0426 45 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 3 40 9.0E-13 T 14-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_16095 2f04cae4b93a1e4d08b42c43ddae0426 45 Pfam PF00468 Ribosomal protein L34 3 45 4.0E-20 T 14-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_16095 2f04cae4b93a1e4d08b42c43ddae0426 45 ProSitePatterns PS00784 Ribosomal protein L34 signature. 3 22 - T 14-10-2018 IPR020939 Ribosomal protein L34, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MB46_16095 2f04cae4b93a1e4d08b42c43ddae0426 45 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 2 45 15.45 T 14-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MB46_10035 95e8352a90db25ffb5631ff4aae14bfd 151 Pfam PF10901 Protein of unknown function (DUF2690) 34 99 1.3E-4 T 14-10-2018 IPR021224 Protein of unknown function DUF2690 MB46_12950 13ca8367ef182629d7b251d6c4be4ae4 209 Pfam PF08666 SAF domain 24 97 9.7E-7 T 14-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 MB46_12950 13ca8367ef182629d7b251d6c4be4ae4 209 SMART SM00858 22 100 1.9E-4 T 14-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 MB46_12950 13ca8367ef182629d7b251d6c4be4ae4 209 Pfam PF16976 Flp pilus assembly protein RcpC/CpaB 104 207 2.2E-8 T 14-10-2018 IPR031571 Flp pilus assembly protein RcpC/CpaB domain MB46_03620 793ad39c2f62fbd2afae37e83475221f 269 Gene3D G3DSA:3.20.20.60 3 269 2.2E-70 T 14-10-2018 MB46_03620 793ad39c2f62fbd2afae37e83475221f 269 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 5 210 8.9E-26 T 14-10-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 MB46_03620 793ad39c2f62fbd2afae37e83475221f 269 PIRSF PIRSF015582 1 269 1.4E-64 T 14-10-2018 IPR011206 Citrate lyase beta subunit-like MB46_03620 793ad39c2f62fbd2afae37e83475221f 269 SUPERFAMILY SSF51621 4 222 4.19E-56 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 MB46_03700 58f64f3ac99f138686c48e06f853ba44 90 Gene3D G3DSA:1.10.287.1060 1 90 1.0E-6 T 14-10-2018 MB46_03700 58f64f3ac99f138686c48e06f853ba44 90 SUPERFAMILY SSF158414 9 60 1.83E-5 T 14-10-2018 IPR029013 HP0062-like domain superfamily MB46_12665 31cc1198f78a3a490d72d42e57cff1a0 411 Pfam PF02601 Exonuclease VII, large subunit 346 407 4.6E-9 T 14-10-2018 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 MB46_12665 31cc1198f78a3a490d72d42e57cff1a0 411 Pfam PF02601 Exonuclease VII, large subunit 139 359 2.1E-61 T 14-10-2018 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 MB46_12665 31cc1198f78a3a490d72d42e57cff1a0 411 Pfam PF13742 OB-fold nucleic acid binding domain 26 115 6.9E-12 T 14-10-2018 IPR025824 OB-fold nucleic acid binding domain GO:0003676 MB46_12665 31cc1198f78a3a490d72d42e57cff1a0 411 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 20 411 21.783 T 14-10-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 MB46_12665 31cc1198f78a3a490d72d42e57cff1a0 411 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 27 408 4.6E-118 T 14-10-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 MB46_01380 cca5487e46dd036ee3db1ac304667c04 395 Pfam PF02653 Branched-chain amino acid transport system / permease component 45 380 1.3E-43 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 MB46_12390 bd1dd7cafb1167e477d1610b91f2ee7e 146 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 40 58 2.9E-8 T 14-10-2018 MB46_12390 bd1dd7cafb1167e477d1610b91f2ee7e 146 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 1 21 2.9E-8 T 14-10-2018 MB46_12390 bd1dd7cafb1167e477d1610b91f2ee7e 146 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 21 40 2.9E-8 T 14-10-2018 MB46_05140 7ac7131d837fd776d198b53098e99a54 438 TIGRFAM TIGR01981 sufD: FeS assembly protein SufD 159 425 5.6E-72 T 14-10-2018 IPR011542 SUF system FeS cluster assembly, SufD GO:0016226 MB46_05140 7ac7131d837fd776d198b53098e99a54 438 Pfam PF01458 Uncharacterized protein family (UPF0051) 188 408 1.3E-69 T 14-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 MB46_05140 7ac7131d837fd776d198b53098e99a54 438 SUPERFAMILY SSF101960 75 433 1.83E-82 T 14-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily MB46_11410 f17f02f8a93f2a29bd3a48d1ac9362c9 255 Pfam PF00535 Glycosyl transferase family 2 15 123 5.8E-24 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MB46_11410 f17f02f8a93f2a29bd3a48d1ac9362c9 255 Gene3D G3DSA:3.90.550.10 4 248 1.6E-35 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MB46_11410 f17f02f8a93f2a29bd3a48d1ac9362c9 255 SUPERFAMILY SSF53448 15 227 3.09E-40 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MB46_19245 a8062d675e2fc0166afae7a180e62435 75 TIGRFAM TIGR01653 lactococcin_972: bacteriocin, lactococcin 972 family 8 73 4.9E-9 T 14-10-2018 IPR006540 Bacteriocin, lactococcin 972 MB46_19245 a8062d675e2fc0166afae7a180e62435 75 Gene3D G3DSA:2.60.40.2850 10 74 5.4E-7 T 14-10-2018 MB46_19245 a8062d675e2fc0166afae7a180e62435 75 Pfam PF09683 Bacteriocin (Lactococcin_972) 9 72 1.3E-9 T 14-10-2018 IPR006540 Bacteriocin, lactococcin 972 MB46_02175 b900a9aa565dc695e44e270c65361e50 156 Pfam PF00293 NUDIX domain 22 136 7.1E-15 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MB46_02175 b900a9aa565dc695e44e270c65361e50 156 Gene3D G3DSA:3.90.79.10 2 138 3.5E-33 T 14-10-2018 MB46_02175 b900a9aa565dc695e44e270c65361e50 156 SUPERFAMILY SSF55811 7 148 2.3E-26 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 MB46_01680 48748d76ca4b6158165be7c97a5a4c23 482 SUPERFAMILY SSF51445 8 327 1.26E-68 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily MB46_01680 48748d76ca4b6158165be7c97a5a4c23 482 Gene3D G3DSA:3.20.20.300 5 341 1.6E-92 T 14-10-2018 IPR036962 Glycoside hydrolase, family 3, N-terminal domain superfamily GO:0004553|GO:0005975 MB46_01680 48748d76ca4b6158165be7c97a5a4c23 482 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 27 325 1.2E-64 T 14-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 MB46_05360 b9a3f407a2f141b2e333c36ac42f96fc 313 Gene3D G3DSA:3.20.20.100 1 313 2.5E-89 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily MB46_05360 b9a3f407a2f141b2e333c36ac42f96fc 313 Pfam PF00248 Aldo/keto reductase family 16 307 3.4E-60 T 14-10-2018 IPR023210 NADP-dependent oxidoreductase domain MB46_05360 b9a3f407a2f141b2e333c36ac42f96fc 313 SUPERFAMILY SSF51430 1 307 4.32E-83 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily MB46_19320 f85615232c55f233ce54ab11429adbbc 136 Pfam PF06250 Protein of unknown function (DUF1016) 2 98 5.5E-26 T 14-10-2018 IPR009362 Protein of unknown function DUF1016 MB46_07785 b8d06634dee1eb840a15c74d68791be2 351 Gene3D G3DSA:3.40.50.300 68 214 2.9E-13 T 14-10-2018 MB46_07785 b8d06634dee1eb840a15c74d68791be2 351 Pfam PF03969 AFG1-like ATPase 36 219 5.9E-39 T 14-10-2018 IPR005654 ATPase, AFG1-like GO:0005524 MB46_07785 b8d06634dee1eb840a15c74d68791be2 351 Pfam PF03969 AFG1-like ATPase 229 339 1.1E-15 T 14-10-2018 IPR005654 ATPase, AFG1-like GO:0005524 MB46_07785 b8d06634dee1eb840a15c74d68791be2 351 SUPERFAMILY SSF52540 78 185 6.26E-10 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_03740 069a13bce3e011a018eee58f8a84367b 613 SUPERFAMILY SSF47240 455 571 5.41E-7 T 14-10-2018 IPR009078 Ferritin-like superfamily MB46_03740 069a13bce3e011a018eee58f8a84367b 613 Pfam PF14530 Domain of unknown function (DUF4439) 458 568 3.4E-8 T 14-10-2018 IPR029447 Domain of unknown function DUF4439 MB46_03515 55aeebc5843781b346649248fdba81d8 199 TIGRFAM TIGR03543 divI1A_rptt_fam: DivIVA domain repeat protein 15 194 5.8E-61 T 14-10-2018 IPR019932 Conserved hypothetical protein CHP03543 MB46_03515 55aeebc5843781b346649248fdba81d8 199 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 156 188 1.0E-6 T 14-10-2018 IPR019933 DivIVA domain MB46_03515 55aeebc5843781b346649248fdba81d8 199 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 49 82 2.0E-9 T 14-10-2018 IPR019933 DivIVA domain MB46_01515 5fd2847155d241c3fec22d638192cf14 299 SUPERFAMILY SSF161098 59 289 1.16E-62 T 14-10-2018 IPR035906 MetI-like superfamily MB46_01515 5fd2847155d241c3fec22d638192cf14 299 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 91 293 1.9E-17 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_01515 5fd2847155d241c3fec22d638192cf14 299 Gene3D G3DSA:1.10.3720.10 55 298 6.7E-72 T 14-10-2018 IPR035906 MetI-like superfamily MB46_07445 a4703cf9bad4244a999811f357a1a7dc 82 Pfam PF06305 Lipopolysaccharide assembly protein A domain 27 78 8.9E-7 T 14-10-2018 IPR010445 Lipopolysaccharide assembly protein A domain GO:0005887 MB46_00275 cb326ea50bf32e44448ef6289573369d 134 Gene3D G3DSA:3.30.429.10 2 134 1.2E-43 T 14-10-2018 IPR014347 Tautomerase/MIF superfamily MB46_00275 cb326ea50bf32e44448ef6289573369d 134 SUPERFAMILY SSF55331 2 128 1.93E-29 T 14-10-2018 IPR014347 Tautomerase/MIF superfamily MB46_00275 cb326ea50bf32e44448ef6289573369d 134 Pfam PF14552 Tautomerase enzyme 38 118 4.1E-25 T 14-10-2018 IPR037479 Tautomerase, MSAD family MB46_19385 ace0ebe9a79d450732c15a7594bd1e50 431 Gene3D G3DSA:3.40.190.10 146 412 5.3E-92 T 14-10-2018 MB46_19385 ace0ebe9a79d450732c15a7594bd1e50 431 Gene3D G3DSA:3.40.190.10 53 350 5.3E-92 T 14-10-2018 MB46_19385 ace0ebe9a79d450732c15a7594bd1e50 431 SUPERFAMILY SSF53850 36 417 1.55E-54 T 14-10-2018 MB46_19385 ace0ebe9a79d450732c15a7594bd1e50 431 Pfam PF01547 Bacterial extracellular solute-binding protein 47 327 3.1E-31 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein MB46_05235 c420f477be44390aa962d667deec67a8 259 Pfam PF01925 Sulfite exporter TauE/SafE 10 249 8.1E-37 T 14-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 MB46_14650 2fdc012c8629bc95b5a68493bd6d8afe 285 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 165 249 7.1E-13 T 14-10-2018 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain MB46_15820 1611e673fcff0e2a668070707f9ea675 389 Pfam PF11202 Phosphoribosyl transferase (PRTase) 16 265 2.3E-102 T 14-10-2018 IPR011215 Phosphoribosyl transferase MB46_15820 1611e673fcff0e2a668070707f9ea675 389 Pfam PF15608 PELOTA RNA binding domain 292 371 9.0E-36 T 14-10-2018 IPR028157 PELOTA RNA-binding domain MB46_15820 1611e673fcff0e2a668070707f9ea675 389 PIRSF PIRSF020979 10 373 2.2E-84 T 14-10-2018 IPR011215 Phosphoribosyl transferase MB46_14370 1171de0f97c6b9f40426c34e9b223f3e 387 Gene3D G3DSA:3.40.50.970 11 371 5.4E-102 T 14-10-2018 MB46_14370 1171de0f97c6b9f40426c34e9b223f3e 387 Pfam PF00676 Dehydrogenase E1 component 64 327 2.2E-69 T 14-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 MB46_14370 1171de0f97c6b9f40426c34e9b223f3e 387 SUPERFAMILY SSF52518 54 373 9.83E-89 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold MB46_07355 a11eceb446d0dea742c567d62ecc0f87 125 Pfam PF13396 Phospholipase_D-nuclease N-terminal 20 63 6.3E-7 T 14-10-2018 IPR027379 Cardiolipin synthase N-terminal MB46_00120 98a7ffc245227d995092e062b722e7a2 459 SUPERFAMILY SSF52540 31 315 2.76E-7 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_00120 98a7ffc245227d995092e062b722e7a2 459 SUPERFAMILY SSF46785 354 422 1.11E-5 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_10705 86eb360940096cfa09d7b57ed85c02c9 122 Gene3D G3DSA:1.10.10.10 1 112 1.7E-16 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_10705 86eb360940096cfa09d7b57ed85c02c9 122 Pfam PF00392 Bacterial regulatory proteins, gntR family 2 57 5.3E-6 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MB46_10705 86eb360940096cfa09d7b57ed85c02c9 122 SUPERFAMILY SSF46785 3 64 3.27E-10 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_00905 f35604a0c3a61fb4cacd3d26f4e6f030 100 Pfam PF11662 Protein of unknown function (DUF3263) 22 94 1.2E-36 T 14-10-2018 IPR021678 Protein of unknown function DUF3263 MB46_01245 695e5968a4e363948d50ba282ed373fd 644 Gene3D G3DSA:1.25.40.10 454 617 5.5E-8 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MB46_01245 695e5968a4e363948d50ba282ed373fd 644 SUPERFAMILY SSF48452 515 608 2.71E-6 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MB46_01245 695e5968a4e363948d50ba282ed373fd 644 Pfam PF17128 Domain of unknown function (DUF5107) 42 335 1.1E-44 T 14-10-2018 IPR033396 Domain of unknown function DUF5107 MB46_08770 8f851398b04126809cd26c207e121e2a 245 SUPERFAMILY SSF55681 19 240 2.68E-42 T 14-10-2018 MB46_08770 8f851398b04126809cd26c207e121e2a 245 Gene3D G3DSA:3.30.930.10 5 244 4.3E-38 T 14-10-2018 MB46_13080 07765af96649bb31fb7405bcb3b96855 411 SUPERFAMILY SSF53335 56 226 2.52E-20 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MB46_13080 07765af96649bb31fb7405bcb3b96855 411 Gene3D G3DSA:3.40.50.150 84 250 9.5E-33 T 14-10-2018 MB46_18270 b9a73d041be3a6b8f59f44e6311ae2c5 234 Gene3D G3DSA:3.40.30.10 1 208 1.9E-79 T 14-10-2018 MB46_18270 b9a73d041be3a6b8f59f44e6311ae2c5 234 SUPERFAMILY SSF52833 1 210 2.11E-45 T 14-10-2018 IPR036249 Thioredoxin-like superfamily MB46_18270 b9a73d041be3a6b8f59f44e6311ae2c5 234 Pfam PF01323 DSBA-like thioredoxin domain 2 204 2.2E-44 T 14-10-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590|Reactome: R-HSA-9033241 MB46_14470 cf12dcf0ebffe49512256c9fde8df427 264 SUPERFAMILY SSF52096 13 263 8.36E-59 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MB46_14470 cf12dcf0ebffe49512256c9fde8df427 264 Pfam PF00378 Enoyl-CoA hydratase/isomerase 26 263 1.1E-44 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 MB46_14470 cf12dcf0ebffe49512256c9fde8df427 264 Gene3D G3DSA:3.90.226.10 11 264 5.5E-61 T 14-10-2018 MB46_00950 8ee7235a75750fc321079665bc32880b 272 SUPERFAMILY SSF53335 14 223 1.69E-42 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MB46_00950 8ee7235a75750fc321079665bc32880b 272 Pfam PF08241 Methyltransferase domain 78 175 2.0E-22 T 14-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 MB46_00950 8ee7235a75750fc321079665bc32880b 272 Gene3D G3DSA:3.40.50.150 5 234 1.0E-44 T 14-10-2018 MB46_10360 285384e13546cd9d64dca44e1ad3d106 390 TIGRFAM TIGR01537 portal_HK97: phage portal protein, HK97 family 32 359 5.1E-48 T 14-10-2018 IPR006427 Phage portal protein, HK97 MB46_10360 285384e13546cd9d64dca44e1ad3d106 390 Gene3D G3DSA:2.40.500.30 55 304 2.1E-5 T 14-10-2018 MB46_10360 285384e13546cd9d64dca44e1ad3d106 390 Gene3D G3DSA:3.30.1120.70 197 243 2.1E-5 T 14-10-2018 MB46_10360 285384e13546cd9d64dca44e1ad3d106 390 Pfam PF04860 Phage portal protein 39 355 2.1E-55 T 14-10-2018 IPR006944 Bacteriophage/Gene transfer agent portal protein MB46_10360 285384e13546cd9d64dca44e1ad3d106 390 Gene3D G3DSA:1.20.1270.210 32 296 2.1E-5 T 14-10-2018 MB46_11675 772e7f69eacf815d057fa9efe57b32b5 302 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 111 280 3.5E-16 T 14-10-2018 IPR013830 SGNH hydrolase-type esterase domain MB46_11675 772e7f69eacf815d057fa9efe57b32b5 302 SUPERFAMILY SSF52266 102 291 1.24E-22 T 14-10-2018 MB46_11675 772e7f69eacf815d057fa9efe57b32b5 302 Gene3D G3DSA:3.40.50.1110 101 294 2.3E-19 T 14-10-2018 IPR036514 SGNH hydrolase superfamily MB46_09675 47e6655acba197f1b5d801defa419c27 171 Pfam PF01613 Flavin reductase like domain 17 160 1.4E-38 T 14-10-2018 IPR002563 Flavin reductase like domain GO:0010181 MB46_09675 47e6655acba197f1b5d801defa419c27 171 SMART SM00903 16 159 2.6E-63 T 14-10-2018 IPR002563 Flavin reductase like domain GO:0010181 MB46_09675 47e6655acba197f1b5d801defa419c27 171 Gene3D G3DSA:2.30.110.10 5 167 2.3E-55 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 MB46_09675 47e6655acba197f1b5d801defa419c27 171 SUPERFAMILY SSF50475 8 158 1.03E-49 T 14-10-2018 MB46_04405 56a1f6374374a21b1578ae3c0e7988bb 446 Pfam PF13434 L-lysine 6-monooxygenase (NADPH-requiring) 16 351 1.4E-119 T 14-10-2018 IPR025700 L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase MB46_04405 56a1f6374374a21b1578ae3c0e7988bb 446 SUPERFAMILY SSF51905 14 279 9.37E-21 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_04405 56a1f6374374a21b1578ae3c0e7988bb 446 Gene3D G3DSA:3.50.50.60 10 432 8.5E-118 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MB46_13580 de8efd0cf109ee0f63726ae80abb42a7 187 SUPERFAMILY SSF46785 11 182 5.45E-25 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_13580 de8efd0cf109ee0f63726ae80abb42a7 187 Gene3D G3DSA:1.10.10.10 10 98 5.5E-16 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_13580 de8efd0cf109ee0f63726ae80abb42a7 187 Pfam PF03551 Transcriptional regulator PadR-like family 15 89 4.1E-9 T 14-10-2018 IPR005149 Transcription regulator PadR, N-terminal MB46_11450 877f94a1f5240f645a9cdd9bfc5f1fb5 371 Pfam PF01757 Acyltransferase family 36 354 4.8E-23 T 14-10-2018 IPR002656 Acyltransferase 3 GO:0016747 MB46_13590 bfd434cfe03a7f191d8349207b0e1f30 200 Hamap MF_01297 UPF0678 fatty acid-binding protein-like protein . 5 199 28.868 T 14-10-2018 IPR022939 Uncharacterised protein family UPF0678 MB46_13590 bfd434cfe03a7f191d8349207b0e1f30 200 SUPERFAMILY SSF50814 8 197 2.03E-38 T 14-10-2018 IPR012674 Calycin MB46_13590 bfd434cfe03a7f191d8349207b0e1f30 200 Gene3D G3DSA:2.40.128.20 102 199 1.6E-20 T 14-10-2018 IPR012674 Calycin MB46_13590 bfd434cfe03a7f191d8349207b0e1f30 200 Gene3D G3DSA:2.40.128.20 2 96 9.9E-25 T 14-10-2018 IPR012674 Calycin MB46_13590 bfd434cfe03a7f191d8349207b0e1f30 200 Pfam PF08768 Domain of unknown function (DUF1794) 12 197 8.4E-43 T 14-10-2018 IPR014878 Domain of unknown function DUF1794 MB46_12920 efa81a77b95c4d1bb85820375c2d237e 258 Gene3D G3DSA:3.40.50.720 4 257 5.3E-28 T 14-10-2018 MB46_12920 efa81a77b95c4d1bb85820375c2d237e 258 SUPERFAMILY SSF51735 4 227 7.73E-27 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_12920 efa81a77b95c4d1bb85820375c2d237e 258 Pfam PF13460 NAD(P)H-binding 8 184 1.5E-15 T 14-10-2018 IPR016040 NAD(P)-binding domain MB46_03030 57dc7a35a83bf3f72e26c334386daf54 444 Pfam PF14067 LssY C-terminus 88 277 5.8E-75 T 14-10-2018 IPR025902 LssY-like C-terminal domain MB46_02680 5998932aef70c99676c5867af3c27533 238 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 203 234 4.4E-4 T 14-10-2018 MB46_16350 e26616769602649b1c9abf6992876690 343 SUPERFAMILY SSF53067 112 334 2.41E-30 T 14-10-2018 MB46_16350 e26616769602649b1c9abf6992876690 343 Gene3D G3DSA:3.30.420.40 113 252 1.5E-48 T 14-10-2018 MB46_16350 e26616769602649b1c9abf6992876690 343 Gene3D G3DSA:3.30.420.40 4 112 1.5E-48 T 14-10-2018 MB46_16350 e26616769602649b1c9abf6992876690 343 SUPERFAMILY SSF53067 3 109 6.98E-12 T 14-10-2018 MB46_16350 e26616769602649b1c9abf6992876690 343 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 7 317 3.8E-20 T 14-10-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 MB46_09725 86f6b9066785a92d51804938783def4d 169 SUPERFAMILY SSF55729 27 147 3.21E-19 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase MB46_09725 86f6b9066785a92d51804938783def4d 169 Pfam PF00583 Acetyltransferase (GNAT) family 56 144 2.9E-10 T 14-10-2018 IPR000182 GNAT domain MB46_09725 86f6b9066785a92d51804938783def4d 169 Gene3D G3DSA:3.40.630.30 10 167 1.5E-24 T 14-10-2018 MB46_02360 8c3a1bedb1be6d3b55d374beb0e98a5e 267 Pfam PF06271 RDD family 16 144 1.5E-18 T 14-10-2018 IPR010432 RDD MB46_00435 a3c90872c7e713778dbcaee9c4a7141e 300 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 108 288 1.2E-17 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_00435 a3c90872c7e713778dbcaee9c4a7141e 300 Gene3D G3DSA:1.10.3720.10 19 290 1.1E-59 T 14-10-2018 IPR035906 MetI-like superfamily MB46_00435 a3c90872c7e713778dbcaee9c4a7141e 300 SUPERFAMILY SSF161098 28 300 2.62E-64 T 14-10-2018 IPR035906 MetI-like superfamily MB46_03725 25cba0239b843c7fde79ed78aca2784f 266 Pfam PF01925 Sulfite exporter TauE/SafE 17 254 3.8E-41 T 14-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 MB46_17470 3c667945b2415c92b1efbfd9f4805121 232 Pfam PF16481 Domain of unknown function (DUF5058) 6 222 4.6E-58 T 14-10-2018 IPR032479 Protein of unknown function DUF5058 MB46_15545 f4fd1ce1be6d360750139521b8bf0442 502 Pfam PF08757 CotH kinase protein 202 468 1.5E-29 T 14-10-2018 IPR014867 Spore coat protein CotH MB46_08500 9bd77955abf1c97577769d8bd420c720 203 Hamap MF_01219 Bifunctional protein PyrR [pyrR]. 21 197 33.179 T 14-10-2018 IPR023050 Bifunctional protein PyrR KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 MB46_08500 9bd77955abf1c97577769d8bd420c720 203 SUPERFAMILY SSF53271 22 189 4.06E-39 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like MB46_08500 9bd77955abf1c97577769d8bd420c720 203 Pfam PF00156 Phosphoribosyl transferase domain 28 166 4.6E-23 T 14-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 MB46_08500 9bd77955abf1c97577769d8bd420c720 203 Gene3D G3DSA:3.40.50.2020 13 202 3.9E-55 T 14-10-2018 MB46_12195 1a2cdcb37b8f1a58e96dcfcb7b92210d 159 SUPERFAMILY SSF55811 8 139 2.17E-25 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 MB46_12195 1a2cdcb37b8f1a58e96dcfcb7b92210d 159 ProSitePatterns PS00893 Nudix box signature. 42 63 - T 14-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 MB46_12195 1a2cdcb37b8f1a58e96dcfcb7b92210d 159 Gene3D G3DSA:3.90.79.10 8 142 3.1E-25 T 14-10-2018 MB46_12195 1a2cdcb37b8f1a58e96dcfcb7b92210d 159 Pfam PF00293 NUDIX domain 11 137 2.6E-19 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MB46_11320 de7928b54d40157385d6c7020b9a0090 304 PIRSF PIRSF003097 1 304 1.0E-66 T 14-10-2018 IPR004513 Cell division protein FtsX GO:0016021 MB46_11320 de7928b54d40157385d6c7020b9a0090 304 Gene3D G3DSA:3.30.70.3040 44 166 9.1E-25 T 14-10-2018 MB46_11320 de7928b54d40157385d6c7020b9a0090 304 Pfam PF02687 FtsX-like permease family 210 300 6.9E-8 T 14-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 MB46_12770 24c8aba1bced723118944862dc34ba45 130 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 40 69 1.0E-8 T 14-10-2018 IPR019933 DivIVA domain MB46_12770 24c8aba1bced723118944862dc34ba45 130 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 83 118 1.6E-9 T 14-10-2018 IPR019933 DivIVA domain MB46_07150 b871e03400d0457d9ade3f9255c6e9cb 405 Gene3D G3DSA:3.40.710.10 63 398 1.3E-77 T 14-10-2018 MB46_07150 b871e03400d0457d9ade3f9255c6e9cb 405 Pfam PF00144 Beta-lactamase 73 389 1.5E-56 T 14-10-2018 IPR001466 Beta-lactamase-related MB46_07150 b871e03400d0457d9ade3f9255c6e9cb 405 SUPERFAMILY SSF56601 67 382 5.12E-72 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like MB46_19925 96f2b895bb4e8da433da2679764126b6 126 SUPERFAMILY SSF88659 10 68 7.19E-5 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like MB46_05445 285f79a0fa5568ca3c3954418dde5722 100 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 4 75 17.359 T 14-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 MB46_05445 285f79a0fa5568ca3c3954418dde5722 100 Pfam PF02416 mttA/Hcf106 family 7 54 9.4E-14 T 14-10-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 MB46_16890 984333089bc2a56f736995a63e24ec0b 348 PIRSF PIRSF015921 2 341 5.7E-69 T 14-10-2018 IPR012171 Fatty acid desaturase GO:0006629|GO:0016021|GO:0016491 MB46_16890 984333089bc2a56f736995a63e24ec0b 348 Pfam PF00487 Fatty acid desaturase 56 314 2.9E-38 T 14-10-2018 IPR005804 Fatty acid desaturase domain GO:0006629 MB46_09895 82a01e50a0fd6260abb363c9ff1b142f 170 Pfam PF12028 Protein of unknown function (DUF3515) 36 148 2.1E-17 T 14-10-2018 IPR021903 Protein of unknown function DUF3515 MB46_11275 36d37abff276f912be597ff7ef1ff6f3 137 Pfam PF10823 Protein of unknown function (DUF2568) 38 126 3.1E-18 T 14-10-2018 IPR021214 Protein of unknown function DUF2568 MB46_18915 f139de28081c929d62d2e5fc0bfc7c48 120 Gene3D G3DSA:1.10.10.10 11 118 4.3E-28 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_18915 f139de28081c929d62d2e5fc0bfc7c48 120 Pfam PF03551 Transcriptional regulator PadR-like family 23 93 5.3E-18 T 14-10-2018 IPR005149 Transcription regulator PadR, N-terminal MB46_18915 f139de28081c929d62d2e5fc0bfc7c48 120 SUPERFAMILY SSF46785 18 111 6.67E-22 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_05195 4aca862c7f026b386e554d16caae09f4 165 Gene3D G3DSA:3.90.960.10 12 165 5.4E-36 T 14-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 MB46_05195 4aca862c7f026b386e554d16caae09f4 165 SUPERFAMILY SSF55826 17 160 9.94E-33 T 14-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 MB46_05195 4aca862c7f026b386e554d16caae09f4 165 Pfam PF04073 Aminoacyl-tRNA editing domain 37 155 3.5E-24 T 14-10-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 MB46_00790 d9f0408cee331eaba21ab377cb45aed7 92 Pfam PF00381 PTS HPr component phosphorylation site 3 86 1.6E-23 T 14-10-2018 IPR000032 Phosphocarrier protein HPr-like MB46_00790 d9f0408cee331eaba21ab377cb45aed7 92 SUPERFAMILY SSF55594 1 90 2.62E-21 T 14-10-2018 IPR035895 HPr-like superfamily MB46_00790 d9f0408cee331eaba21ab377cb45aed7 92 PRINTS PR00107 Phosphocarrier protein signature 57 74 2.6E-8 T 14-10-2018 IPR000032 Phosphocarrier protein HPr-like MB46_00790 d9f0408cee331eaba21ab377cb45aed7 92 PRINTS PR00107 Phosphocarrier protein signature 42 57 2.6E-8 T 14-10-2018 IPR000032 Phosphocarrier protein HPr-like MB46_00790 d9f0408cee331eaba21ab377cb45aed7 92 PRINTS PR00107 Phosphocarrier protein signature 13 29 2.6E-8 T 14-10-2018 IPR000032 Phosphocarrier protein HPr-like MB46_00790 d9f0408cee331eaba21ab377cb45aed7 92 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 1 86 6.7E-24 T 14-10-2018 IPR000032 Phosphocarrier protein HPr-like MB46_00790 d9f0408cee331eaba21ab377cb45aed7 92 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 13 20 - T 14-10-2018 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site MB46_00790 d9f0408cee331eaba21ab377cb45aed7 92 Gene3D G3DSA:3.30.1340.10 1 89 1.0E-22 T 14-10-2018 IPR035895 HPr-like superfamily MB46_00620 de6b497bcacf737707a57b4e59867055 410 Gene3D G3DSA:2.130.10.10 225 408 6.3E-9 T 14-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 MB46_00620 de6b497bcacf737707a57b4e59867055 410 SUPERFAMILY SSF50998 55 400 1.41E-10 T 14-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily MB46_06375 73845df4f9d2a1c43e4b86e287b6f3bc 101 Pfam PF03992 Antibiotic biosynthesis monooxygenase 8 77 1.9E-10 T 14-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain MB46_06375 73845df4f9d2a1c43e4b86e287b6f3bc 101 Gene3D G3DSA:3.30.70.100 1 99 3.2E-19 T 14-10-2018 MB46_06375 73845df4f9d2a1c43e4b86e287b6f3bc 101 SUPERFAMILY SSF54909 4 94 4.6E-19 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel MB46_12900 ae4b511c9dd3cf1305fae876f65c57bc 570 SUPERFAMILY SSF56112 104 457 1.47E-19 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily MB46_12900 ae4b511c9dd3cf1305fae876f65c57bc 570 Pfam PF03109 ABC1 family 122 246 7.6E-28 T 14-10-2018 IPR004147 UbiB domain MB46_13170 06f286cf2acde6449a8ec476f3cf0a21 131 ProDom PD004028 INHIBITOR PROTEASE SERINE DIRECT SEQUENCING SUBTILISIN PRECURSOR SIGNAL INHIBITOR-LIKE INHIBITOR 49 112 3.0E-5 T 14-10-2018 IPR023549 Subtilisin inhibitor GO:0004867 MB46_13170 06f286cf2acde6449a8ec476f3cf0a21 131 Gene3D G3DSA:3.30.350.10 13 121 1.3E-7 T 14-10-2018 IPR036819 Subtilisin inhibitor-like superfamily GO:0004867 MB46_13170 06f286cf2acde6449a8ec476f3cf0a21 131 SUPERFAMILY SSF55399 27 121 2.75E-19 T 14-10-2018 IPR036819 Subtilisin inhibitor-like superfamily GO:0004867 MB46_11210 165a0d5bda5debf651926bbcdd4a3edc 274 Pfam PF13349 Putative adhesin 31 246 9.9E-9 T 14-10-2018 IPR025164 Putative adhesin MB46_02350 d3043ea47a63f81fd38b3d2eb62132d2 126 Pfam PF07811 TadE-like protein 9 51 2.6E-10 T 14-10-2018 IPR012495 TadE-like MB46_11170 ecf403ab85029c8967bd057726111611 313 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 311 7.1E-35 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_11170 ecf403ab85029c8967bd057726111611 313 SUPERFAMILY SSF161098 91 298 1.02E-18 T 14-10-2018 IPR035906 MetI-like superfamily MB46_11170 ecf403ab85029c8967bd057726111611 313 Gene3D G3DSA:1.10.3720.10 84 306 3.8E-23 T 14-10-2018 IPR035906 MetI-like superfamily MB46_00690 38e2e773da02736f2f30673af312cba3 522 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 239 438 1.4E-13 T 14-10-2018 IPR000477 Reverse transcriptase domain MB46_00690 38e2e773da02736f2f30673af312cba3 522 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 394 405 7.7E-16 T 14-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 MB46_00690 38e2e773da02736f2f30673af312cba3 522 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 361 374 7.7E-16 T 14-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 MB46_00690 38e2e773da02736f2f30673af312cba3 522 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 379 392 7.7E-16 T 14-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 MB46_00690 38e2e773da02736f2f30673af312cba3 522 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 240 252 7.7E-16 T 14-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 MB46_00690 38e2e773da02736f2f30673af312cba3 522 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 448 454 7.7E-16 T 14-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 MB46_15770 557320539986468cd52b13c84d346c38 376 Pfam PF04332 Protein of unknown function (DUF475) 44 362 1.4E-121 T 14-10-2018 IPR007427 Protein of unknown function DUF475 MB46_01880 810672949aa1d7a825dfe2b3824c4fda 281 Pfam PF11139 Sap, sulfolipid-1-addressing protein 28 269 3.7E-26 T 14-10-2018 IPR021315 Glycolipid exporter Gap/Sap MB46_16055 e90ef9446990160f687e7cace952b833 221 SMART SM00507 47 99 1.1E-5 T 14-10-2018 IPR003615 HNH nuclease MB46_16055 e90ef9446990160f687e7cace952b833 221 Pfam PF01844 HNH endonuclease 63 99 6.4E-6 T 14-10-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 MB46_01050 85910c95577c0e4a25fb92dc7b9b4553 111 Hamap MF_00010 UPF0060 membrane protein YnfA [ynfA]. 4 109 20.809 T 14-10-2018 IPR003844 Uncharacterised protein family UPF0060 GO:0016020 MB46_01050 85910c95577c0e4a25fb92dc7b9b4553 111 Pfam PF02694 Uncharacterised BCR, YnfA/UPF0060 family 3 110 1.1E-41 T 14-10-2018 IPR003844 Uncharacterised protein family UPF0060 GO:0016020 MB46_01050 85910c95577c0e4a25fb92dc7b9b4553 111 SUPERFAMILY SSF103481 9 108 3.27E-9 T 14-10-2018 MB46_18875 83b9bc64850e922f2ab457a4a4b0d1be 338 Pfam PF02653 Branched-chain amino acid transport system / permease component 55 326 1.4E-47 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 MB46_01475 55785acae0de0e157cecbe59d05f1ad0 261 Gene3D G3DSA:2.60.40.10 166 260 7.7E-22 T 14-10-2018 IPR013783 Immunoglobulin-like fold MB46_01475 55785acae0de0e157cecbe59d05f1ad0 261 SUPERFAMILY SSF81296 165 236 1.54E-5 T 14-10-2018 IPR014756 Immunoglobulin E-set MB46_09360 58a01034047a887aebc23ac1df09cbfb 269 Pfam PF07510 Protein of unknown function (DUF1524) 115 252 3.1E-13 T 14-10-2018 IPR011089 Domain of unknown function DUF1524 MB46_15245 2582ac3ddc30b037677e4b496cf08d44 213 SUPERFAMILY SSF53474 5 203 1.37E-32 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_15245 2582ac3ddc30b037677e4b496cf08d44 213 Gene3D G3DSA:3.40.50.1820 3 206 8.3E-33 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_15245 2582ac3ddc30b037677e4b496cf08d44 213 Pfam PF02230 Phospholipase/Carboxylesterase 12 205 2.3E-10 T 14-10-2018 IPR003140 Phospholipase/carboxylesterase/thioesterase GO:0016787 MB46_13055 23aaf0b9db53753948dc124486749259 270 Pfam PF01061 ABC-2 type transporter 13 226 5.2E-22 T 14-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 MB46_13055 23aaf0b9db53753948dc124486749259 270 PIRSF PIRSF006648 8 264 6.7E-26 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 MB46_14700 1725be8cf4caaa8ff5180eecfea560f9 384 Pfam PF12679 ABC-2 family transporter protein 12 220 6.8E-9 T 14-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 MB46_05430 fa4e3fc2c2972ba199d051de35e47b0e 131 SUPERFAMILY SSF54534 20 130 1.3E-37 T 14-10-2018 MB46_05430 fa4e3fc2c2972ba199d051de35e47b0e 131 Gene3D G3DSA:3.10.50.40 6 131 1.6E-40 T 14-10-2018 MB46_05430 fa4e3fc2c2972ba199d051de35e47b0e 131 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 38 128 2.7E-28 T 14-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain MB46_00240 021034ea5787fa98ac21c9cf58eb9a87 229 Pfam PF04854 Protein of unknown function, DUF624 55 118 1.1E-8 T 14-10-2018 IPR006938 Protein of unknown function DUF624 MB46_04650 f0e42695b2bc7a4ef4aadaaddc3c5d7f 530 Gene3D G3DSA:1.10.260.150 80 371 1.0E-66 T 14-10-2018 MB46_04650 f0e42695b2bc7a4ef4aadaaddc3c5d7f 530 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 406 489 9.2E-9 T 14-10-2018 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain MB46_04650 f0e42695b2bc7a4ef4aadaaddc3c5d7f 530 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 123 282 1.1E-35 T 14-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain MB46_04650 f0e42695b2bc7a4ef4aadaaddc3c5d7f 530 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 124 281 2.4E-39 T 14-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain MB46_10670 b16948232c61acb1cb79000a53731715 118 Pfam PF02656 Domain of unknown function (DUF202) 16 82 4.8E-17 T 14-10-2018 IPR003807 Domain of unknown function DUF202 MB46_04400 18caac38e44aff6129003fde77b96628 186 SMART SM01006 6 53 1.3E-16 T 14-10-2018 IPR019432 Siderophore biosynthesis protein, conserved domain MB46_04400 18caac38e44aff6129003fde77b96628 186 SUPERFAMILY SSF55729 1 167 2.06E-43 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase MB46_04400 18caac38e44aff6129003fde77b96628 186 Pfam PF13523 Acetyltransferase (GNAT) domain 10 152 1.7E-47 T 14-10-2018 MB46_04400 18caac38e44aff6129003fde77b96628 186 Gene3D G3DSA:3.40.630.30 1 168 5.3E-53 T 14-10-2018 MB46_16960 4c75a15e62fad15b6d9841642f94c4eb 125 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 12 98 2.8E-24 T 14-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 MB46_16960 4c75a15e62fad15b6d9841642f94c4eb 125 Pfam PF03334 Na+/H+ antiporter subunit 13 91 5.8E-25 T 14-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 MB46_00090 04d689e34fb2eff98e0ecc17eed0c466 485 Pfam PF00982 Glycosyltransferase family 20 19 479 2.6E-142 T 14-10-2018 IPR001830 Glycosyl transferase, family 20 GO:0003824|GO:0005992 KEGG: 00500+2.4.1.15 MB46_00090 04d689e34fb2eff98e0ecc17eed0c466 485 Gene3D G3DSA:3.40.50.2000 256 464 8.3E-163 T 14-10-2018 MB46_00090 04d689e34fb2eff98e0ecc17eed0c466 485 SUPERFAMILY SSF53756 18 478 6.91E-140 T 14-10-2018 MB46_00090 04d689e34fb2eff98e0ecc17eed0c466 485 Gene3D G3DSA:3.40.50.2000 43 475 8.3E-163 T 14-10-2018 MB46_15910 b6238a7600efafc7d1858a5e96eedc64 223 Pfam PF01569 PAP2 superfamily 107 215 3.5E-15 T 14-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MB46_15910 b6238a7600efafc7d1858a5e96eedc64 223 SMART SM00014 105 209 4.0E-12 T 14-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MB46_15910 b6238a7600efafc7d1858a5e96eedc64 223 SUPERFAMILY SSF48317 23 216 1.28E-34 T 14-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily MB46_15910 b6238a7600efafc7d1858a5e96eedc64 223 Gene3D G3DSA:1.20.144.10 25 137 1.1E-7 T 14-10-2018 MB46_15910 b6238a7600efafc7d1858a5e96eedc64 223 Gene3D G3DSA:1.20.144.10 138 223 4.3E-17 T 14-10-2018 MB46_18510 c65d1ac22d2152b39390889f5d87be70 124 Pfam PF08818 Domain of unknown function (DU1801) 33 123 2.4E-8 T 14-10-2018 IPR014922 Domain of unknown function DUF1801 MB46_16480 25d3f8ba4ff761950d9da987b5ddbc48 128 Pfam PF06993 Protein of unknown function (DUF1304) 11 123 1.4E-32 T 14-10-2018 IPR009732 Protein of unknown function DUF1304 MB46_11545 2bc496f5dd182b50c5587f9f1ae4d264 292 Pfam PF01061 ABC-2 type transporter 27 241 2.3E-22 T 14-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 MB46_13740 eec312bac68896b98b55ec0e412a342a 188 SUPERFAMILY SSF46689 6 74 2.1E-14 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MB46_13740 eec312bac68896b98b55ec0e412a342a 188 Gene3D G3DSA:1.10.357.10 3 183 3.2E-30 T 14-10-2018 MB46_13740 eec312bac68896b98b55ec0e412a342a 188 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 54 9.5E-12 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MB46_13740 eec312bac68896b98b55ec0e412a342a 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 11 24 5.0E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MB46_13740 eec312bac68896b98b55ec0e412a342a 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 5.0E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MB46_12150 dd8792bcb196ea0a534f46cc53a1d2a4 309 Gene3D G3DSA:3.40.50.720 6 308 7.8E-34 T 14-10-2018 MB46_12150 dd8792bcb196ea0a534f46cc53a1d2a4 309 Pfam PF01370 NAD dependent epimerase/dehydratase family 6 210 5.9E-12 T 14-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 MB46_12150 dd8792bcb196ea0a534f46cc53a1d2a4 309 SUPERFAMILY SSF51735 6 307 4.8E-36 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_01110 cdf434741ea006602664296c5f98f5ec 102 Pfam PF00581 Rhodanese-like domain 12 92 5.5E-13 T 14-10-2018 IPR001763 Rhodanese-like domain MB46_01110 cdf434741ea006602664296c5f98f5ec 102 Gene3D G3DSA:3.40.250.10 1 100 3.5E-28 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily MB46_01110 cdf434741ea006602664296c5f98f5ec 102 SMART SM00450 2 96 2.8E-18 T 14-10-2018 IPR001763 Rhodanese-like domain MB46_01110 cdf434741ea006602664296c5f98f5ec 102 SUPERFAMILY SSF52821 8 99 8.51E-28 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily MB46_16245 4d4fd4102efef7c832474a60f25945bf 124 Pfam PF04020 Mycobacterial 4 TMS phage holin, superfamily IV 10 107 3.3E-7 T 14-10-2018 IPR007165 Mycobacterial 4 TMS phage holin, superfamily IV MB46_14270 423b47aff8178f0e4b1a40c65ebea469 406 Pfam PF12698 ABC-2 family transporter protein 21 381 2.7E-31 T 14-10-2018 MB46_11960 d628b3b554834a7c422b5ff390c47355 196 Pfam PF01863 Protein of unknown function DUF45 105 171 7.4E-19 T 14-10-2018 IPR002725 Protein of unknown function DUF45 MB46_11960 d628b3b554834a7c422b5ff390c47355 196 Gene3D G3DSA:3.30.2010.10 96 173 3.6E-10 T 14-10-2018 MB46_05175 c50e64b9e4f24d39ce5d19e832668546 216 Pfam PF02361 Cobalt transport protein 18 206 4.5E-10 T 14-10-2018 IPR003339 ABC/ECF transporter, transmembrane component MB46_19025 f02ee5fd806c8ae128fbbae03c9eaf41 119 Pfam PF10724 Protein of unknown function (DUF2516) 8 107 2.8E-26 T 14-10-2018 IPR019662 Protein of unknown function DUF2516 MB46_11805 59c45043243032d49e286d4eb192aace 678 Gene3D G3DSA:3.10.310.50 25 167 1.0E-30 T 14-10-2018 MB46_11805 59c45043243032d49e286d4eb192aace 678 Pfam PF04536 TPM domain 42 157 3.0E-17 T 14-10-2018 IPR007621 TPM domain MB46_02615 9ef7aecff50281a4ae82059e6bccc6f9 122 SUPERFAMILY SSF47226 13 114 8.24E-11 T 14-10-2018 IPR036641 HPT domain superfamily GO:0000160 MB46_02615 9ef7aecff50281a4ae82059e6bccc6f9 122 Gene3D G3DSA:1.20.120.160 2 117 1.9E-9 T 14-10-2018 IPR036641 HPT domain superfamily GO:0000160 MB46_19510 d7f165a5a2130b67d4571ec6feca9444 148 Gene3D G3DSA:1.10.260.40 13 147 6.3E-18 T 14-10-2018 MB46_09230 717de924d4b655fb984ed1b2528bc6d6 182 Pfam PF13376 Bacteriocin-protection, YdeI or OmpD-Associated 124 181 1.6E-9 T 14-10-2018 MB46_07780 842574e9250e700d2384e745cc9da0e4 64 Pfam PF14013 MT0933-like antitoxin protein 9 54 2.0E-17 T 14-10-2018 IPR028037 Antitoxin Rv0909/MT0933 MB46_06980 4e9350d3168e58cc26824b9b9e410858 126 SUPERFAMILY SSF54593 1 120 3.24E-15 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MB46_06980 4e9350d3168e58cc26824b9b9e410858 126 Gene3D G3DSA:3.10.180.10 2 124 1.8E-24 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MB46_06310 986cfa0c0b8ffa091978453cf8fe8191 393 Pfam PF00232 Glycosyl hydrolase family 1 270 389 5.3E-22 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 MB46_06310 986cfa0c0b8ffa091978453cf8fe8191 393 Pfam PF00232 Glycosyl hydrolase family 1 3 164 3.8E-41 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 MB46_06310 986cfa0c0b8ffa091978453cf8fe8191 393 PRINTS PR00131 Glycosyl hydrolase family 1 signature 335 352 7.1E-13 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 MB46_06310 986cfa0c0b8ffa091978453cf8fe8191 393 PRINTS PR00131 Glycosyl hydrolase family 1 signature 359 371 7.1E-13 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 MB46_06310 986cfa0c0b8ffa091978453cf8fe8191 393 PRINTS PR00131 Glycosyl hydrolase family 1 signature 302 310 7.1E-13 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 MB46_06310 986cfa0c0b8ffa091978453cf8fe8191 393 PRINTS PR00131 Glycosyl hydrolase family 1 signature 246 260 7.1E-13 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 MB46_06310 986cfa0c0b8ffa091978453cf8fe8191 393 PRINTS PR00131 Glycosyl hydrolase family 1 signature 314 325 7.1E-13 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 MB46_06310 986cfa0c0b8ffa091978453cf8fe8191 393 Gene3D G3DSA:3.20.20.80 1 393 3.7E-102 T 14-10-2018 MB46_06310 986cfa0c0b8ffa091978453cf8fe8191 393 SUPERFAMILY SSF51445 2 391 2.47E-102 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily MB46_04895 9bdd18cc7026935113c0d67c7c6be560 89 Pfam PF04226 Transglycosylase associated protein 34 83 1.5E-7 T 14-10-2018 IPR007341 Transglycosylase-associated protein GO:0016021 MB46_08430 641dec76c0c4b296591174ee8663af90 117 Gene3D G3DSA:3.30.40.60 3 62 2.0E-6 T 14-10-2018 MB46_17260 17acd06e99ae11b92e257f9aac723470 334 Pfam PF06089 L-asparaginase II 15 324 1.2E-105 T 14-10-2018 IPR010349 L-asparaginase II MB46_06385 c21f71049389d467f47aa2ee14217cb9 73 Gene3D G3DSA:3.20.20.60 1 66 5.5E-10 T 14-10-2018 MB46_06385 c21f71049389d467f47aa2ee14217cb9 73 SUPERFAMILY SSF51621 1 66 2.51E-10 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 MB46_11365 6e303a6be363b7c084cc2ba09f4deaa8 284 Pfam PF00482 Type II secretion system (T2SS), protein F 112 237 2.8E-9 T 14-10-2018 IPR018076 Type II secretion system F domain MB46_09545 76aa765dc0f55ac551a2b1321cd460c8 110 Pfam PF10611 Protein of unknown function (DUF2469) 1 101 6.7E-52 T 14-10-2018 IPR019592 Protein of unknown function DUF2469 MB46_18335 3bf1252f84ed5d3541331f4b981af19e 447 Pfam PF11299 Protein of unknown function (DUF3100) 29 261 1.0E-90 T 14-10-2018 IPR021450 Protein of unknown function DUF3100 MB46_16000 f1d702870d6fba16453fb38ba0586c79 129 Pfam PF03724 META domain 53 123 1.1E-12 T 14-10-2018 IPR005184 Domain of unknown function DUF306, Meta/HslJ MB46_16000 f1d702870d6fba16453fb38ba0586c79 129 Gene3D G3DSA:2.40.128.270 29 128 3.2E-11 T 14-10-2018 IPR038670 HslJ-like superfamily MB46_12380 8c0a3bb9da5615d1134ea138e88f128e 184 Pfam PF06210 Protein of unknown function (DUF1003) 29 131 4.7E-44 T 14-10-2018 IPR010406 Protein of unknown function DUF1003 MB46_11340 335436da52eb8fadcb34974a770d5de1 158 Pfam PF13400 Putative Flp pilus-assembly TadE/G-like 23 67 5.5E-5 T 14-10-2018 IPR028087 Putative Flp pilus-assembly TadG-like, N-terminal MB46_06020 0c44095d0e8a3f282eadb10de6ec6f9c 293 SUPERFAMILY SSF161098 23 290 1.78E-64 T 14-10-2018 IPR035906 MetI-like superfamily MB46_06020 0c44095d0e8a3f282eadb10de6ec6f9c 293 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 103 278 5.8E-22 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_06020 0c44095d0e8a3f282eadb10de6ec6f9c 293 Gene3D G3DSA:1.10.3720.10 25 281 1.8E-57 T 14-10-2018 IPR035906 MetI-like superfamily MB46_02735 54ba15051a919d0cd12d4888c158e501 364 Pfam PF01757 Acyltransferase family 12 340 1.1E-28 T 14-10-2018 IPR002656 Acyltransferase 3 GO:0016747 MB46_11155 8b0bea2d0283fbef75c91d2c34001a49 278 Gene3D G3DSA:3.20.20.150 1 274 1.9E-50 T 14-10-2018 MB46_11155 8b0bea2d0283fbef75c91d2c34001a49 278 Pfam PF01261 Xylose isomerase-like TIM barrel 16 202 3.5E-16 T 14-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain MB46_11155 8b0bea2d0283fbef75c91d2c34001a49 278 SUPERFAMILY SSF51658 12 256 3.73E-36 T 14-10-2018 IPR036237 Xylose isomerase-like superfamily MB46_18535 f1a23c0f08fb39ff1b6fa6070fdf8887 220 Pfam PF14016 Protein of unknown function (DUF4232) 85 219 3.2E-29 T 14-10-2018 IPR025326 Protein of unknown function DUF4232 MB46_16135 dd53175fb411e60c404b01129bdfc6dd 130 Pfam PF12089 Transmembrane domain of unknown function (DUF3566) 10 129 1.4E-41 T 14-10-2018 IPR021949 Domain of unknown function DUF3566. transmembrane MB46_11500 2272b5f85c24759aea9b1739b96e9527 400 Pfam PF13440 Polysaccharide biosynthesis protein 7 303 7.6E-23 T 14-10-2018 MB46_00205 517a4f03563d7c29dafe84e767e928be 637 Pfam PF07944 Beta-L-arabinofuranosidase, GH127 36 544 1.1E-118 T 14-10-2018 IPR012878 Beta-L-arabinofuranosidase, GH127 MB46_00205 517a4f03563d7c29dafe84e767e928be 637 SUPERFAMILY SSF48208 73 413 1.02E-24 T 14-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 MB46_10575 edab5fa5b73ace0c6a423c2293c60de4 175 Pfam PF04138 GtrA-like protein 44 161 4.4E-10 T 14-10-2018 IPR007267 GtrA-like protein GO:0000271|GO:0016021 MB46_01100 8cc075743c05a206ac830a41ba85a592 406 Pfam PF07690 Major Facilitator Superfamily 8 317 4.0E-40 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MB46_01100 8cc075743c05a206ac830a41ba85a592 406 Gene3D G3DSA:1.20.1250.20 194 380 1.8E-18 T 14-10-2018 MB46_01100 8cc075743c05a206ac830a41ba85a592 406 Gene3D G3DSA:1.20.1250.20 3 185 4.1E-31 T 14-10-2018 MB46_01100 8cc075743c05a206ac830a41ba85a592 406 SUPERFAMILY SSF103473 4 379 2.35E-58 T 14-10-2018 IPR036259 MFS transporter superfamily MB46_09240 7bcf2b10688e0e0737de7771fdf83e8b 216 SUPERFAMILY SSF53474 16 205 1.51E-32 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_09240 7bcf2b10688e0e0737de7771fdf83e8b 216 Pfam PF02230 Phospholipase/Carboxylesterase 17 206 7.3E-15 T 14-10-2018 IPR003140 Phospholipase/carboxylesterase/thioesterase GO:0016787 MB46_09240 7bcf2b10688e0e0737de7771fdf83e8b 216 Gene3D G3DSA:3.40.50.1820 9 207 9.4E-37 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold MB46_16680 b6d37c09f87a59f79b67bd2944dd0aed 349 Gene3D G3DSA:3.40.710.30 1 349 3.3E-118 T 14-10-2018 MB46_16680 b6d37c09f87a59f79b67bd2944dd0aed 349 SUPERFAMILY SSF56601 8 332 8.31E-45 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like MB46_16680 b6d37c09f87a59f79b67bd2944dd0aed 349 Pfam PF00144 Beta-lactamase 9 325 6.0E-43 T 14-10-2018 IPR001466 Beta-lactamase-related MB46_13310 6d374b06f88493a0091799880c1a16f3 449 Pfam PF13416 Bacterial extracellular solute-binding protein 74 376 4.4E-47 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein MB46_13310 6d374b06f88493a0091799880c1a16f3 449 Gene3D G3DSA:3.40.190.10 54 446 5.9E-93 T 14-10-2018 MB46_13310 6d374b06f88493a0091799880c1a16f3 449 SUPERFAMILY SSF53850 57 435 1.7E-70 T 14-10-2018 MB46_00975 1fd27a41417804591938d3456933b2fa 195 Pfam PF11228 Protein of unknown function (DUF3027) 63 159 1.9E-27 T 14-10-2018 IPR021391 Protein of unknown function DUF3027 MB46_12630 0697f6561812647075953f1415ad06c1 255 TIGRFAM TIGR03843 TIGR03843: conserved hypothetical protein 8 255 2.0E-106 T 14-10-2018 IPR022292 Conserved hypothetical protein CHP03843 MB46_10335 83c79953ed6c5cf19db96ea9825fbf45 379 Gene3D G3DSA:3.30.40.60 89 202 2.1E-8 T 14-10-2018 MB46_16590 7dd99528dcc7d6ac090ebe5e3900d02f 197 Gene3D G3DSA:3.40.430.10 1 187 1.6E-37 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 MB46_16590 7dd99528dcc7d6ac090ebe5e3900d02f 197 SUPERFAMILY SSF53597 1 172 1.44E-21 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 MB46_16590 7dd99528dcc7d6ac090ebe5e3900d02f 197 Pfam PF01872 RibD C-terminal domain 1 177 4.2E-21 T 14-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 MB46_05470 dbc252621667ec8b96cd5f26f8ae617e 113 Gene3D G3DSA:2.20.28.270 1 79 3.8E-32 T 14-10-2018 IPR038638 RbpA superfamily MB46_05470 dbc252621667ec8b96cd5f26f8ae617e 113 Pfam PF13397 RNA polymerase-binding protein 4 106 1.6E-39 T 14-10-2018 IPR025182 RNA polymerase-binding protein RbpA GO:0001000|GO:0045893 MB46_05470 dbc252621667ec8b96cd5f26f8ae617e 113 Hamap MF_01483 RNA polymerase-binding protein RbpA [rbpA]. 16 111 22.48 T 14-10-2018 IPR025182 RNA polymerase-binding protein RbpA GO:0001000|GO:0045893 MB46_13100 9c6234f3b8b11f0c01c7250c7470f007 129 Pfam PF06993 Protein of unknown function (DUF1304) 11 123 7.0E-31 T 14-10-2018 IPR009732 Protein of unknown function DUF1304 MB46_12905 acc73e0b212249b3f68246613d7850b8 180 SUPERFAMILY SSF46785 42 115 3.24E-26 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_12905 acc73e0b212249b3f68246613d7850b8 180 Pfam PF03551 Transcriptional regulator PadR-like family 46 114 5.0E-23 T 14-10-2018 IPR005149 Transcription regulator PadR, N-terminal MB46_12905 acc73e0b212249b3f68246613d7850b8 180 Gene3D G3DSA:1.10.10.10 34 121 3.1E-26 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_08030 2c060c7dbd658afdb0e8efc1a734822b 422 Pfam PF13830 Domain of unknown function (DUF4192) 15 396 2.7E-40 T 14-10-2018 IPR025447 Protein of unknown function DUF4192 MB46_06410 ae1857a196acfca206cb25ba850a9a9a 266 PIRSF PIRSF006648 1 265 4.6E-70 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 MB46_06410 ae1857a196acfca206cb25ba850a9a9a 266 Pfam PF01061 ABC-2 type transporter 13 217 4.7E-30 T 14-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 MB46_02550 31bf7d9736474a1381f1cd6f4b02095e 207 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 170 203 0.0016 T 14-10-2018 MB46_10415 9e1b60a7d15b5a0f37d8de7b8e458751 290 Pfam PF05709 Phage tail protein 38 261 1.6E-9 T 14-10-2018 IPR008841 Siphovirus-type tail component MB46_03985 7e2290f6c63622a3e1b89ba9e641905a 296 Pfam PF07179 SseB protein N-terminal domain 58 179 9.3E-30 T 14-10-2018 IPR009839 SseB protein N-terminal domain MB46_15535 67b269b1f07d6eae39992c3ebbd0700a 259 SUPERFAMILY SSF55154 63 237 1.67E-5 T 14-10-2018 IPR033469 CYTH-like domain superfamily Reactome: R-HSA-196819 MB46_15535 67b269b1f07d6eae39992c3ebbd0700a 259 Pfam PF09359 VTC domain 31 125 1.9E-8 T 14-10-2018 IPR018966 VTC domain MB46_07835 01176258612da85c1603cc161985d419 192 Pfam PF11452 Protein of unknown function (DUF3000) 8 181 2.5E-72 T 14-10-2018 IPR021555 Protein of unknown function DUF3000 MB46_10860 deaa8e59aacca0c38d513267d6e04263 183 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 27 172 1.1E-27 T 14-10-2018 IPR005864 ATP synthase, F0 complex, subunit b, bacterial GO:0015078|GO:0015986|GO:0045263 MB46_10860 deaa8e59aacca0c38d513267d6e04263 183 Hamap MF_01398 ATP synthase subunit b [atpF]. 12 154 12.749 T 14-10-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 MB46_10860 deaa8e59aacca0c38d513267d6e04263 183 SUPERFAMILY SSF81573 79 137 1.44E-12 T 14-10-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain superfamily MB46_10860 deaa8e59aacca0c38d513267d6e04263 183 Gene3D G3DSA:1.20.5.620 78 138 6.1E-7 T 14-10-2018 MB46_10860 deaa8e59aacca0c38d513267d6e04263 183 Pfam PF00430 ATP synthase B/B' CF(0) 23 152 2.7E-26 T 14-10-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 MB46_07350 b4244e49cf3d0607561ab8c33a515bda 534 Pfam PF03806 AbgT putative transporter family 1 533 8.7E-138 T 14-10-2018 IPR004697 p-Aminobenzoyl-glutamate transport protein AbgT GO:0015558|GO:1902604 MB46_10765 7c25c2db501b8c22c98683535864e374 108 Pfam PF11238 Protein of unknown function (DUF3039) 38 92 2.2E-31 T 14-10-2018 IPR021400 Protein of unknown function DUF3039 MB46_08990 4d484251b6ef41b5d9a7237299416366 142 Pfam PF14017 Protein of unknown function (DUF4233) 25 124 1.3E-26 T 14-10-2018 IPR025327 Protein of unknown function DUF4233 MB46_18435 f7ab894dc6c77adcad82eec014c4c33f 160 Pfam PF03780 Asp23 family, cell envelope-related function 22 129 9.4E-28 T 14-10-2018 IPR005531 Alkaline shock protein Asp23 MB46_07590 db297d446f9b3934ebcdf9c981f34169 125 Pfam PF13396 Phospholipase_D-nuclease N-terminal 20 63 2.3E-6 T 14-10-2018 IPR027379 Cardiolipin synthase N-terminal MB46_12560 2d676d24b46745616c95a2947ba93c48 158 Pfam PF04978 Protein of unknown function (DUF664) 8 154 3.5E-40 T 14-10-2018 IPR007061 Protein of unknown function DUF664 MB46_12560 2d676d24b46745616c95a2947ba93c48 158 SUPERFAMILY SSF109854 1 153 9.01E-34 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes MB46_12560 2d676d24b46745616c95a2947ba93c48 158 Gene3D G3DSA:1.20.120.450 1 155 3.4E-30 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes MB46_10665 d752051474f5f1a9a3edc52156dc90f6 141 ProDom PD277113 MEMBRANE INNER YIDG TRANSMEMBRANE STY3975 RV2273/MT2334 MB2296 20 53 4.0E-5 T 14-10-2018 IPR020264 Uncharacterised protein family YidG MB46_10665 d752051474f5f1a9a3edc52156dc90f6 141 Pfam PF02656 Domain of unknown function (DUF202) 20 91 6.1E-12 T 14-10-2018 IPR003807 Domain of unknown function DUF202 MB46_08900 e7c8fe31d59f8ca5f92506c96101a4b4 133 SUPERFAMILY SSF54427 28 129 9.93E-29 T 14-10-2018 IPR032710 NTF2-like domain superfamily MB46_08900 e7c8fe31d59f8ca5f92506c96101a4b4 133 Gene3D G3DSA:3.10.450.50 1 132 4.5E-32 T 14-10-2018 MB46_10700 51e7bf99762b365a5271677c00897bda 317 SUPERFAMILY SSF52540 3 220 1.21E-39 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_10700 51e7bf99762b365a5271677c00897bda 317 SMART SM00382 30 208 2.5E-4 T 14-10-2018 IPR003593 AAA+ ATPase domain MB46_10700 51e7bf99762b365a5271677c00897bda 317 Pfam PF00005 ABC transporter 21 157 5.4E-15 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MB46_10700 51e7bf99762b365a5271677c00897bda 317 Gene3D G3DSA:3.40.50.300 1 227 1.1E-34 T 14-10-2018 MB46_06995 ee33929f72d9cf8115d56b39e0e2c40b 220 SUPERFAMILY SSF56112 6 188 3.83E-9 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily MB46_03665 3c437e484028fd86b4c6ba5661f19878 206 Gene3D G3DSA:1.10.10.10 96 181 2.7E-5 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_12225 feb0d8eb80fe9eecdf4b6af6781fa006 146 SUPERFAMILY SSF53927 40 139 1.92E-20 T 14-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 MB46_12225 feb0d8eb80fe9eecdf4b6af6781fa006 146 Gene3D G3DSA:3.40.140.10 10 146 2.7E-26 T 14-10-2018 MB46_15875 a0e8ef4b3f22a6830dee808b7fdde629 216 Pfam PF07077 Protein of unknown function (DUF1345) 38 205 3.4E-52 T 14-10-2018 IPR009781 Protein of unknown function DUF1345 MB46_09535 e99cd9e538cb389b2a390e1301ccdfee 214 Gene3D G3DSA:3.40.50.720 3 214 5.8E-40 T 14-10-2018 MB46_09535 e99cd9e538cb389b2a390e1301ccdfee 214 Pfam PF13460 NAD(P)H-binding 8 160 5.2E-18 T 14-10-2018 IPR016040 NAD(P)-binding domain MB46_09535 e99cd9e538cb389b2a390e1301ccdfee 214 SUPERFAMILY SSF51735 2 212 5.15E-27 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily MB46_11285 6bc1948e820b9ce41cf79a55528c4adc 99 Pfam PF13834 Domain of unknown function (DUF4193) 1 98 3.4E-39 T 14-10-2018 IPR025242 Protein of unknown function DUF4193 MB46_18040 4f17bb2811001f7c0a1d32a8c2a5548d 143 Pfam PF12158 Protein of unknown function (DUF3592) 4 139 3.8E-12 T 14-10-2018 IPR021994 Protein of unknown function DUF3592 MB46_10095 22b6c35104b098fb44db2641c4d798f9 172 Gene3D G3DSA:1.10.10.10 11 148 2.8E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MB46_10095 22b6c35104b098fb44db2641c4d798f9 172 SUPERFAMILY SSF46785 17 150 8.96E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MB46_10095 22b6c35104b098fb44db2641c4d798f9 172 Pfam PF01047 MarR family 41 96 1.6E-10 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MB46_10095 22b6c35104b098fb44db2641c4d798f9 172 SMART SM00347 33 133 1.1E-11 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MB46_19825 e442ecf2af63fb8b0087e192276a7e1b 106 Pfam PF13518 Helix-turn-helix domain 14 68 4.0E-11 T 14-10-2018 MB46_19825 e442ecf2af63fb8b0087e192276a7e1b 106 SUPERFAMILY SSF46689 7 104 2.87E-17 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MB46_01720 0a907b018afd66c1ce92dd4fcb07fcac 401 Pfam PF02653 Branched-chain amino acid transport system / permease component 91 360 1.0E-45 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 MB46_07990 c958efc5bde3f876218ffd25fe2fad2e 528 PIRSF PIRSF006446 1 215 1.6E-79 T 14-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 MB46_07990 c958efc5bde3f876218ffd25fe2fad2e 528 PIRSF PIRSF006446 219 516 4.5E-45 T 14-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 MB46_07990 c958efc5bde3f876218ffd25fe2fad2e 528 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 6 494 1.5E-154 T 14-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 MB46_15680 6d09a2f034d9ddc7014f33bdd1428e54 90 Gene3D G3DSA:1.10.287.1060 2 90 9.0E-8 T 14-10-2018 MB46_08290 9e04f9acce6cc6e5b16acf71104dab76 125 Pfam PF11239 Protein of unknown function (DUF3040) 1 80 9.2E-28 T 14-10-2018 IPR021401 Protein of unknown function DUF3040 MB46_15095 f86e782c7575606deb87e336bf4441ce 167 Pfam PF03780 Asp23 family, cell envelope-related function 20 127 2.8E-23 T 14-10-2018 IPR005531 Alkaline shock protein Asp23 MB46_16190 5b3f8b4435e666af5070b7a2d4c20c9c 84 Pfam PF06781 Cell division protein CrgA 2 83 5.8E-28 T 14-10-2018 IPR009619 Cell division protein CrgA MB46_16190 5b3f8b4435e666af5070b7a2d4c20c9c 84 Hamap MF_00631 Cell division protein CrgA [crgA]. 1 83 25.046 T 14-10-2018 IPR009619 Cell division protein CrgA MB46_17545 b287a88aee069bbf8a8b7ddee8c56248 307 SUPERFAMILY SSF161098 34 307 1.24E-73 T 14-10-2018 IPR035906 MetI-like superfamily MB46_17545 b287a88aee069bbf8a8b7ddee8c56248 307 Gene3D G3DSA:1.10.3720.10 31 294 1.1E-65 T 14-10-2018 IPR035906 MetI-like superfamily MB46_17545 b287a88aee069bbf8a8b7ddee8c56248 307 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 122 300 1.1E-24 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_01805 9c2a5e6adf5105daca753f65c88b60ea 406 Pfam PF01566 Natural resistance-associated macrophage protein 47 370 4.0E-23 T 14-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 MB46_01945 9ea04209f9190029bca5f4f9fc8fb976 371 Gene3D G3DSA:3.40.50.2300 54 326 2.1E-83 T 14-10-2018 MB46_01945 9ea04209f9190029bca5f4f9fc8fb976 371 SUPERFAMILY SSF53822 64 319 9.89E-5 T 14-10-2018 IPR028082 Periplasmic binding protein-like I MB46_01945 9ea04209f9190029bca5f4f9fc8fb976 371 Gene3D G3DSA:3.40.50.2300 154 362 2.1E-83 T 14-10-2018 MB46_01945 9ea04209f9190029bca5f4f9fc8fb976 371 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 56 360 6.3E-45 T 14-10-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 MB46_10120 b0d2ddde48e1645ccc506ea95f838a58 321 SUPERFAMILY SSF161098 81 307 2.75E-56 T 14-10-2018 IPR035906 MetI-like superfamily MB46_10120 b0d2ddde48e1645ccc506ea95f838a58 321 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 310 5.4E-20 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MB46_10120 b0d2ddde48e1645ccc506ea95f838a58 321 Gene3D G3DSA:1.10.3720.10 77 318 2.6E-66 T 14-10-2018 IPR035906 MetI-like superfamily MB46_18645 566c965546291add7220bccead78b27f 204 Gene3D G3DSA:1.10.260.40 72 204 2.0E-18 T 14-10-2018 MB46_15530 9b2b61791474f652f7d11eb180cfbafa 211 Pfam PF16316 Domain of unknown function (DUF4956) 10 177 5.5E-56 T 14-10-2018 IPR032531 Protein of unknown function DUF4956 MB46_11605 5068c508e818d8f932ff67701112b933 284 Gene3D G3DSA:3.10.350.10 224 279 3.0E-7 T 14-10-2018 IPR036779 LysM domain superfamily MB46_09370 b7aa910fb2b79293f59a6933c69ba916 254 Pfam PF03883 Peroxide stress protein YaaA 2 228 3.8E-39 T 14-10-2018 IPR005583 Peroxide stress protein YaaA MB46_03015 60157a096f7f77dc235b749a4dadfd89 185 Gene3D G3DSA:3.40.960.10 81 181 1.5E-5 T 14-10-2018 MB46_11430 7e227b47c3c64ca04cd1537f6eff62d4 125 Pfam PF10066 Uncharacterized conserved protein (DUF2304) 4 104 5.2E-24 T 14-10-2018 IPR019277 Protein of unknown function DUF2304 MB46_08505 d5693f6b76fb727df5c7223f4159e87a 470 Pfam PF13367 Protease prsW family 128 320 4.3E-49 T 14-10-2018 IPR026898 Protease PrsW GO:0008233 MB46_12910 14d9bb71eea22ace79099c0a898ebe0e 337 Pfam PF04657 Putative inner membrane exporter, YdcZ 25 166 5.0E-25 T 14-10-2018 IPR006750 Putative inner membrane exporter, YdcZ MB46_12910 14d9bb71eea22ace79099c0a898ebe0e 337 Pfam PF04657 Putative inner membrane exporter, YdcZ 186 319 6.6E-20 T 14-10-2018 IPR006750 Putative inner membrane exporter, YdcZ MB46_03425 bb7d648903efd86d790b17409532c690 126 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 3 65 2.2E-5 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MB46_16220 5a12131c61c9e27c714d624900fbf455 464 Pfam PF01098 Cell cycle protein 76 435 4.0E-75 T 14-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MB46_12185 00be64548fef4f4776f7351eecc6a36b 138 Pfam PF10990 Protein of unknown function (DUF2809) 38 115 6.4E-21 T 14-10-2018 IPR021257 Protein of unknown function DUF2809 MB46_19010 d7f2500d75e3240403ad611097893158 389 Gene3D G3DSA:3.40.50.300 2 167 1.6E-48 T 14-10-2018 MB46_19010 d7f2500d75e3240403ad611097893158 389 SUPERFAMILY SSF52540 6 207 2.38E-46 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MB46_19010 d7f2500d75e3240403ad611097893158 389 Pfam PF13177 DNA polymerase III, delta subunit 9 167 9.8E-42 T 14-10-2018 MB46_09460 44af4b140c6addc4cc5344b550f30034 139 Pfam PF11253 Protein of unknown function (DUF3052) 13 137 2.1E-53 T 14-10-2018 IPR021412 Protein of unknown function DUF3052 MB46_16555 3195393bf60cc2235741cb4b46dde61f 142 Pfam PF04020 Mycobacterial 4 TMS phage holin, superfamily IV 3 131 2.8E-29 T 14-10-2018 IPR007165 Mycobacterial 4 TMS phage holin, superfamily IV MB46_15850 3a47fa51532850ce20f89cd333b78d2f 206 Pfam PF01810 LysE type translocator 19 204 3.7E-40 T 14-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 MB46_02875 5d282fa936e5a8a0870e3b0e5287e390 565 Pfam PF05960 Bacterial protein of unknown function (DUF885) 30 560 1.1E-152 T 14-10-2018 IPR010281 Protein of unknown function DUF885 MB46_01145 65208a8fff77b288866b89b9a7a09e45 504 Gene3D G3DSA:1.20.1730.10 22 495 6.9E-69 T 14-10-2018 IPR038377 Sodium/glucose symporter superfamily MB46_01145 65208a8fff77b288866b89b9a7a09e45 504 Pfam PF00474 Sodium:solute symporter family 32 425 1.5E-32 T 14-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 MB46_05300 5b4661ea625cab0a1c598273d80fae98 157 Gene3D G3DSA:2.60.40.10 24 116 6.7E-6 T 14-10-2018 IPR013783 Immunoglobulin-like fold MB46_05300 5b4661ea625cab0a1c598273d80fae98 157 SUPERFAMILY SSF49299 36 110 8.63E-5 T 14-10-2018 IPR035986 PKD domain superfamily MB46_02245 88ad1a6c90870468bdf1e7bd84dc2703 246 SUPERFAMILY SSF56801 4 230 1.7E-10 T 14-10-2018 MB46_02245 88ad1a6c90870468bdf1e7bd84dc2703 246 TIGRFAM TIGR03089 TIGR03089: TIGR03089 family protein 11 245 3.6E-54 T 14-10-2018 IPR017523 Conserved hypothetical protein CHP03089 MB46_07455 bc4e052649b6ad526583ff889004704f 281 Pfam PF01925 Sulfite exporter TauE/SafE 10 266 1.6E-38 T 14-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 MB46_02200 4cd80fbbcb666a5583c82de0bf4b3804 212 Pfam PF14030 Protein of unknown function (DUF4245) 21 185 5.2E-44 T 14-10-2018 IPR025339 Protein of unknown function DUF4245 MB46_02965 1029f1fac8861c252fd9e5c18d06e696 93 Gene3D G3DSA:1.10.287.1060 4 93 9.6E-8 T 14-10-2018 MB46_17210 fd7a5246246528b26cb3b30611cf5bf2 288 SUPERFAMILY SSF109604 111 277 8.37E-22 T 14-10-2018 MB46_17210 fd7a5246246528b26cb3b30611cf5bf2 288 Pfam PF13223 Protein of unknown function (DUF4031) 2 75 5.8E-23 T 14-10-2018 IPR025109 Domain of unknown function DUF4031 MB46_17210 fd7a5246246528b26cb3b30611cf5bf2 288 PIRSF PIRSF035170 101 288 1.7E-47 T 14-10-2018 IPR009218 Predicted HD phosphohydrolase MB46_09655 29788059448578d5ca781b4291728b72 273 Pfam PF13845 Septum formation 46 205 3.6E-18 T 14-10-2018 IPR026004 Septum formation-related domain MB46_15775 2b0cda0f05a6d706efc0940711a3390e 197 Gene3D G3DSA:2.60.60.30 20 187 2.4E-53 T 14-10-2018 MB46_15775 2b0cda0f05a6d706efc0940711a3390e 197 Pfam PF02342 TerD domain 1 182 2.7E-50 T 14-10-2018 IPR003325 TerD domain MB46_12095 c5f85a52c72683af1cb9f5f0f347c55b 74 Pfam PF11305 Protein of unknown function (DUF3107) 1 72 8.6E-27 T 14-10-2018 IPR021456 Protein of unknown function DUF3107 MB46_16870 4514b87b464b9265d6fd74bb6154aa95 308 Pfam PF03547 Membrane transport protein 157 300 1.5E-16 T 14-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 MB46_16870 4514b87b464b9265d6fd74bb6154aa95 308 Pfam PF03547 Membrane transport protein 11 143 1.1E-8 T 14-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 MB46_19265 fc2d7aef2679eda883f5bd50665ef27f 86 Gene3D G3DSA:1.10.1220.180 3 78 4.5E-11 T 14-10-2018 MB46_16050 95edf3b56979901245ecf09861f4305c 171 Pfam PF02720 Domain of unknown function (DUF222) 40 143 4.4E-6 T 14-10-2018 IPR003870 Domain of unknown function DUF222 MB46_16630 e49b7304a3f1c2c4a7da3128c7be5923 166 Pfam PF04306 Protein of unknown function (DUF456) 23 158 2.2E-24 T 14-10-2018 IPR007403 Protein of unknown function DUF456 MB46_03735 23d9e409be34b0bb43eb698200ec1e60 243 Pfam PF01988 VIT family 26 233 4.6E-52 T 14-10-2018 IPR008217 Ccc1 family MB46_10140 e48ee4acd013bb7ddc1ba2813d910f95 378 Pfam PF06224 Winged helix DNA-binding domain 32 366 7.1E-46 T 14-10-2018 IPR009351 Protein of unknown function DUF1006 MB46_10020 bd6c8f7ca3a57796b64a22bfe3268499 361 SUPERFAMILY SSF50182 178 243 6.87E-13 T 14-10-2018 IPR010920 LSM domain superfamily MB46_10020 bd6c8f7ca3a57796b64a22bfe3268499 361 Pfam PF00924 Mechanosensitive ion channel 137 326 6.3E-25 T 14-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 MB46_12795 db20a31ebe4d9b234f37cad010f249aa 172 Pfam PF12158 Protein of unknown function (DUF3592) 17 144 6.3E-6 T 14-10-2018 IPR021994 Protein of unknown function DUF3592 MB46_20005 58f78cfb1e8069c2913b7353037cf936 234 Pfam PF13521 AAA domain 2 193 1.9E-17 T 14-10-2018 IPR038727 NadR/Ttd14, AAA domain MB46_19205 58f78cfb1e8069c2913b7353037cf936 234 Pfam PF13521 AAA domain 2 193 1.9E-17 T 14-10-2018 IPR038727 NadR/Ttd14, AAA domain MB46_02555 5b021bd284868b7de84d3d3f679bdb69 627 Pfam PF13196 Protein of unknown function (DUF4012) 234 386 1.3E-42 T 14-10-2018 IPR025101 Protein of unknown function DUF4012 MB46_08795 4c4ef05feb0b73955dad6dec59eeff1a 154 Pfam PF05360 yiaA/B two helix domain 14 66 1.1E-22 T 14-10-2018 IPR008024 YiaAB two helix MB46_08795 4c4ef05feb0b73955dad6dec59eeff1a 154 Pfam PF05360 yiaA/B two helix domain 77 129 2.3E-20 T 14-10-2018 IPR008024 YiaAB two helix MB46_05570 6a75d5183972b52580f57ee4c0ad8a91 159 Pfam PF08592 Domain of unknown function (DUF1772) 22 156 1.2E-14 T 14-10-2018 MB46_09650 3c7bd7e062cc616e2a657eebfa6d6025 189 TIGRFAM TIGR04178 exo_archaeo: exosortase/archaeosortase family protein 89 179 1.1E-6 T 14-10-2018 IPR026392 Exosortase/Archaeosortase domain MB46_15350 a37a0d32c703fa87a8019c1414536d83 377 Pfam PF13515 Fusaric acid resistance protein-like 50 167 1.0E-9 T 14-10-2018 MB46_12975 37aeeaeaf35fb57e1b7047b1e5bf4902 269 Pfam PF02104 SURF1 family 19 236 1.1E-18 T 14-10-2018 IPR002994 Surfeit locus 1/Shy1 GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MB46_15460 95ee00acdc483a472c6ff1eac2bccb2e 178 Pfam PF03703 Bacterial PH domain 90 167 1.6E-14 T 14-10-2018 IPR005182 Domain of unknown function DUF304 MB46_02240 84b8ba3ad90424ca08f57dd4ee4f9d7a 178 Pfam PF04138 GtrA-like protein 34 156 7.5E-24 T 14-10-2018 IPR007267 GtrA-like protein GO:0000271|GO:0016021 MB46_07920 41609c1f2384ea1ce76c0b98065f4359 258 Pfam PF12502 Protein of unknown function (DUF3710) 53 226 6.0E-60 T 14-10-2018 IPR022183 Protein of unknown function DUF3710 MB46_09795 6c93fa2446eee402a5fd6b04d19d6d2c 72 Gene3D G3DSA:2.40.50.140 1 65 1.4E-7 T 14-10-2018 MB46_14610 4497c094f4aa24d7cfcfa9b00b44994b 135 Pfam PF13396 Phospholipase_D-nuclease N-terminal 12 57 1.8E-13 T 14-10-2018 IPR027379 Cardiolipin synthase N-terminal MB46_18475 5088cda51dde2707476cc6d0408ad7c6 204 Pfam PF03780 Asp23 family, cell envelope-related function 102 181 4.3E-7 T 14-10-2018 IPR005531 Alkaline shock protein Asp23 MB46_17230 22fd0a40810efbf6d36f77a13435ab6d 673 Pfam PF13845 Septum formation 555 656 8.7E-6 T 14-10-2018 IPR026004 Septum formation-related domain MB46_05085 754bf00cc2a58e7de076d240cfcffcca 313 Pfam PF10128 Glucose-6-phosphate dehydrogenase subunit 51 296 1.1E-82 T 14-10-2018 IPR004555 Glucose-6-phosphate dehydrogenase assembly protein OpcA MB46_02010 3cce506117b7733817bea2ed649198c9 205 Pfam PF04417 Protein of unknown function (DUF501) 37 164 8.7E-39 T 14-10-2018 IPR007511 Protein of unknown function DUF501 MB46_03555 a52ec53adaff665042d479a83b039261 134 Pfam PF14325 Domain of unknown function (DUF4383) 7 123 2.6E-28 T 14-10-2018 IPR025492 Protein of unknown function DUF4383 MB46_17985 6f054d0b15e3b15de103a4c7c47eab79 560 Gene3D G3DSA:1.10.4160.10 21 405 5.5E-15 T 14-10-2018 IPR038271 Purine-cytosine permease superfamily MB46_14095 5d6874fb700b307a580764e263ca6577 266 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 19 241 4.7E-52 T 14-10-2018 IPR018713 Domain of unknown function DUF2236 MB46_11360 c28294c2079ccef506207aa847665801 312 Pfam PF00482 Type II secretion system (T2SS), protein F 176 301 8.8E-17 T 14-10-2018 IPR018076 Type II secretion system F domain MB46_02005 d136fc80e6822a779ffa867bc3d71a8c 256 Pfam PF04977 Septum formation initiator 117 188 1.1E-15 T 14-10-2018 IPR007060 Septum formation initiator FtsL/DivIC MB46_09010 75897b3dc5d4b34a4bc748519d97035d 114 Pfam PF04343 Protein of unknown function, DUF488 6 110 2.4E-24 T 14-10-2018 IPR007438 Protein of unknown function DUF488 MB46_17780 1fa6ea5b601e8b3f27184546fb316697 251 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 21 229 7.7E-47 T 14-10-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114