locus-tag	class	description
KKR91_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KKR91_00010	COG0592	DNA-directed DNA polymerase activity
KKR91_00015	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
KKR91_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KKR91_00025	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
KKR91_00030	COG0187	DNA topoisomerase II activity
KKR91_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KKR91_00040	COG3266	domain, Protein
KKR91_00075	COG0705	Rhomboid family
KKR91_00085	COG3764	Sortase (surface protein transpeptidase)
KKR91_00105	COG0515	serine threonine protein kinase
KKR91_00110	COG0768	penicillin binding
KKR91_00125	COG1716	ATPase activity
KKR91_00130	COG1716	ATPase activity
KKR91_00150	COG0346	lactoylglutathione lyase activity
KKR91_00165	COG2610	gluconate transmembrane transporter activity
KKR91_00170	COG3265	gluconokinase activity
KKR91_00180	COG0783	Belongs to the Dps family
KKR91_00190	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KKR91_00190	COG0723	plastoquinol--plastocyanin reductase activity
KKR91_00210	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KKR91_00230	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
KKR91_00260	COG0702	epimerase
KKR91_00280	COG1028	Short-chain dehydrogenase reductase Sdr
KKR91_00285	COG1609	Transcriptional regulator
KKR91_00315	COG0561	phosphatase activity
KKR91_00320	COG0671	phosphoesterase, PA-phosphatase related
KKR91_00325	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
KKR91_00330	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KKR91_00335	COG0584	glycerophosphoryl diester phosphodiesterase
KKR91_00340	COG1929	Belongs to the glycerate kinase type-1 family
KKR91_00345	COG2233	PERMEase
KKR91_00350	COG0300	oxidoreductase activity
KKR91_00355	COG1012	belongs to the aldehyde dehydrogenase family
KKR91_00365	COG3104	oligopeptide transport
KKR91_00375	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KKR91_00390	COG1597	lipid kinase activity
KKR91_00395	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KKR91_00400	COG0561	phosphatase activity
KKR91_00415	COG2027	D-alanyl-D-alanine carboxypeptidase
KKR91_00425	COG0037	tRNA processing
KKR91_00435	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KKR91_00440	COG0302	gtp cyclohydrolase
KKR91_00450	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KKR91_00455	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KKR91_00480	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
KKR91_00485	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
KKR91_00505	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
KKR91_00510	COG3237	CsbD-like
KKR91_00515	COG2376	Dihydroxyacetone kinase
KKR91_00520	COG1461	Dihydroxyacetone kinase
KKR91_00530	COG1194	a g-specific adenine glycosylase
KKR91_00540	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
KKR91_00570	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KKR91_00575	COG0306	phosphate transporter
KKR91_00630	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KKR91_00635	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KKR91_00635	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
KKR91_00635	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KKR91_00640	COG1105	Belongs to the carbohydrate kinase PfkB family
KKR91_00660	COG2733	membrane
KKR91_00665	COG3387	PFAM Glycoside hydrolase 15-related
KKR91_00690	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KKR91_00695	COG0280	phosphate acetyltransferase
KKR91_00695	COG0857	belongs to the CobB CobQ family
KKR91_00700	COG0531	amino acid
KKR91_00715	COG2252	PERMEase
KKR91_00800	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KKR91_00820	COG0191	fructose-bisphosphate aldolase activity
KKR91_00840	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KKR91_00860	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KKR91_00875	COG1832	CoA-binding protein
KKR91_00890	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KKR91_00895	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KKR91_00905	COG1116	anion transmembrane transporter activity
KKR91_00925	COG1832	CoA-binding protein
KKR91_00935	COG2315	Protein conserved in bacteria
KKR91_00955	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KKR91_00960	COG0047	phosphoribosylformylglycinamidine synthase activity
KKR91_00965	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KKR91_00995	COG1846	Transcriptional regulator
KKR91_01015	COG4555	ABC transporter
KKR91_01025	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KKR91_01085	COG0739	heme binding
KKR91_01265	COG0629	single-stranded DNA binding
KKR91_01435	COG2197	response regulator
KKR91_01440	COG0300	oxidoreductase activity
KKR91_01445	COG0492	ferredoxin-NADP+ reductase activity
KKR91_01455	COG1309	transcriptional regulator
KKR91_01485	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KKR91_01515	COG1131	(ABC) transporter
KKR91_01545	COG1733	regulation of RNA biosynthetic process
KKR91_01560	COG3903	Transcriptional regulator
KKR91_01560	COG3629	intracellular signal transduction
KKR91_01565	COG1028	Short-chain dehydrogenase reductase Sdr
KKR91_01575	COG2264	protein methyltransferase activity
KKR91_01600	COG1368	sulfuric ester hydrolase activity
KKR91_01635	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KKR91_01640	COG1120	ATPase activity
KKR91_01660	COG0583	DNA-binding transcription factor activity
KKR91_01700	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KKR91_01705	COG2224	Isocitrate lyase
KKR91_01710	COG1396	sequence-specific DNA binding
KKR91_01715	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KKR91_01720	COG1404	Belongs to the peptidase S8 family
KKR91_01725	COG0351	phosphomethylpyrimidine kinase
KKR91_01745	COG0343	queuine tRNA-ribosyltransferase activity
KKR91_01785	COG1960	acyl-CoA dehydrogenase activity
KKR91_01810	COG0564	pseudouridine synthase activity
KKR91_01815	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KKR91_01820	COG1201	RNA secondary structure unwinding
KKR91_01840	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KKR91_01855	COG0515	serine threonine protein kinase
KKR91_01860	COG1674	ftsk spoiiie
KKR91_01990	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KKR91_02000	COG2062	phosphohistidine phosphatase, SixA
KKR91_02020	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
KKR91_02040	COG0514	ATP-dependent DNA helicase (RecQ)
KKR91_02050	COG1024	Enoyl-CoA hydratase
KKR91_02060	COG0667	Aldo Keto reductase
KKR91_02070	COG1505	serine-type exopeptidase activity
KKR91_02095	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KKR91_02115	COG1966	Carbon starvation protein
KKR91_02135	COG0656	L-ascorbic acid biosynthetic process
KKR91_02140	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
KKR91_02145	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KKR91_02150	COG4786	Flagellar basal body rod
KKR91_02150	COG1256	bacterial-type flagellum assembly
KKR91_02165	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KKR91_02170	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KKR91_02195	COG1558	bacterial-type flagellum-dependent cell motility
KKR91_02200	COG1677	Flagellar hook-basal body complex protein FliE
KKR91_02205	COG1766	The M ring may be actively involved in energy transduction
KKR91_02210	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KKR91_02220	COG1157	protein secretion by the type III secretion system
KKR91_02240	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
KKR91_02255	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KKR91_02260	COG1360	Flagellar Motor Protein
KKR91_02270	COG1776	CheC inhibitor of MCP methylation
KKR91_02270	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KKR91_02280	COG1338	Plays a role in the flagellum-specific transport system
KKR91_02295	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KKR91_02300	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KKR91_02310	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
KKR91_02325	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KKR91_02330	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KKR91_02350	COG2140	Oxalate decarboxylase
KKR91_02380	COG0588	phosphoglycerate mutase activity
KKR91_02390	COG5002	protein histidine kinase activity
KKR91_02410	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
KKR91_02415	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
KKR91_02420	COG0215	cysteine-tRNA ligase activity
KKR91_02425	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KKR91_02430	COG1523	belongs to the glycosyl hydrolase 13 family
KKR91_02440	COG0366	Alpha amylase catalytic
KKR91_02450	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KKR91_02495	COG0277	FAD linked oxidase domain protein
KKR91_02500	COG0366	Alpha amylase catalytic
KKR91_02510	COG3842	ATPase activity
KKR91_02520	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
KKR91_02535	COG1301	dicarboxylic acid transport
KKR91_02560	COG1051	belongs to the nudix hydrolase family
KKR91_02580	COG1940	carbohydrate kinase activity
KKR91_02610	COG3621	Patatin-like phospholipase
KKR91_02630	COG1595	DNA-templated transcription, initiation
KKR91_02690	COG2159	amidohydrolase
KKR91_02695	COG2828	Protein conserved in bacteria
KKR91_02715	COG1116	anion transmembrane transporter activity
KKR91_02720	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KKR91_02725	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KKR91_02755	COG0318	PFAM AMP-dependent synthetase and ligase
KKR91_02775	COG0667	Aldo Keto reductase
KKR91_02810	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KKR91_02830	COG0459	protein refolding
KKR91_02840	COG2205	protein histidine kinase activity
KKR91_02845	COG0745	RESPONSE REGULATOR receiver
KKR91_02850	COG1061	Type III restriction enzyme res subunit
KKR91_02865	COG1278	Cold shock
KKR91_02890	COG1321	iron dependent repressor
KKR91_02895	COG0739	heme binding
KKR91_02920	COG0303	'Molybdopterin
KKR91_02925	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KKR91_02930	COG5002	protein histidine kinase activity
KKR91_02935	COG1132	(ABC) transporter
KKR91_02950	COG2409	Drug exporters of the RND superfamily
KKR91_02960	COG0483	inositol monophosphate 1-phosphatase activity
KKR91_02970	COG0045	succinate-CoA ligase (ADP-forming) activity
KKR91_02980	COG2814	Major facilitator Superfamily
KKR91_02990	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KKR91_02995	COG0656	L-ascorbic acid biosynthetic process
KKR91_03005	COG0318	PFAM AMP-dependent synthetase and ligase
KKR91_03015	COG1396	sequence-specific DNA binding
KKR91_03030	COG0028	Belongs to the TPP enzyme family
KKR91_03045	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KKR91_03055	COG3424	synthase
KKR91_03100	COG3655	Transcriptional regulator
KKR91_03125	COG0252	asparaginase activity
KKR91_03145	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KKR91_03155	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KKR91_03160	COG0477	Major facilitator Superfamily
KKR91_03165	COG1957	nucleoside hydrolase
KKR91_03175	COG0477	Major facilitator Superfamily
KKR91_03215	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KKR91_03245	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KKR91_03250	COG0778	Nitroreductase
KKR91_03250	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
KKR91_03255	COG1120	ATPase activity
KKR91_03260	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KKR91_03275	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KKR91_03305	COG1309	transcriptional regulator
KKR91_03315	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KKR91_03320	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
KKR91_03330	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KKR91_03335	COG0363	glucosamine-6-phosphate deaminase activity
KKR91_03345	COG0747	negative chemotaxis
KKR91_03355	COG0444	Belongs to the ABC transporter superfamily
KKR91_03360	COG4608	Belongs to the ABC transporter superfamily
KKR91_03365	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KKR91_03370	COG1940	carbohydrate kinase activity
KKR91_03375	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
KKR91_03395	COG0640	Transcriptional regulator
KKR91_03410	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KKR91_03420	COG5002	protein histidine kinase activity
KKR91_03420	COG2176	DNA-directed DNA polymerase activity
KKR91_03430	COG1914	H( )-stimulated, divalent metal cation uptake system
KKR91_03435	COG1914	H( )-stimulated, divalent metal cation uptake system
KKR91_03440	COG4336	lyase activity
KKR91_03450	COG4770	biotin carboxylase activity
KKR91_03455	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
KKR91_03460	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
KKR91_03505	COG1879	ABC-type sugar transport system periplasmic component
KKR91_03510	COG1129	ABC transporter
KKR91_03515	COG1172	Belongs to the binding-protein-dependent transport system permease family
KKR91_03520	COG1940	carbohydrate kinase activity
KKR91_03525	COG1028	Short-chain dehydrogenase reductase Sdr
KKR91_03545	COG4213	ABC transporter substrate-binding protein
KKR91_03550	COG1129	ABC transporter
KKR91_03555	COG4214	carbohydrate transport
KKR91_03575	COG0800	Aldolase
KKR91_03580	COG1028	Short-chain dehydrogenase reductase Sdr
KKR91_03585	COG1063	alcohol dehydrogenase
KKR91_03595	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
KKR91_03605	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
KKR91_03635	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KKR91_03660	COG2235	arginine
KKR91_03685	COG0446	pyridine nucleotide-disulphide oxidoreductase
KKR91_03685	COG1902	pentaerythritol trinitrate reductase activity
KKR91_03745	COG1358	cellular component organization or biogenesis
KKR91_03795	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KKR91_03800	COG1063	alcohol dehydrogenase
KKR91_03815	COG2115	Belongs to the xylose isomerase family
KKR91_03820	COG1070	Carbohydrate kinase
KKR91_03825	COG2017	converts alpha-aldose to the beta-anomer
KKR91_03835	COG3458	cephalosporin-C deacetylase activity
KKR91_03840	COG1472	Belongs to the glycosyl hydrolase 3 family
KKR91_03850	COG1175	transmembrane transport
KKR91_03860	COG1609	Transcriptional regulator
KKR91_03865	COG2814	Major facilitator Superfamily
KKR91_03880	COG2390	Transcriptional regulator
KKR91_03885	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KKR91_03890	COG0738	Major facilitator superfamily
KKR91_03900	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KKR91_03905	COG1063	alcohol dehydrogenase
KKR91_03915	COG1175	transmembrane transport
KKR91_03920	COG0395	ABC-type sugar transport system, permease component
KKR91_03935	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KKR91_03940	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
KKR91_03945	COG0667	Aldo Keto reductase
KKR91_03950	COG1012	belongs to the aldehyde dehydrogenase family
KKR91_03955	COG0404	The glycine cleavage system catalyzes the degradation of glycine
KKR91_03965	COG0277	FAD linked oxidase domain protein
KKR91_03970	COG1546	Belongs to the CinA family
KKR91_03975	COG0247	lactate metabolic process
KKR91_03980	COG1139	Iron-sulfur cluster binding protein
KKR91_03985	COG1556	Lactate utilization protein
KKR91_04000	COG0404	The glycine cleavage system catalyzes the degradation of glycine
KKR91_04010	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KKR91_04030	COG1620	l-lactate permease
KKR91_04040	COG3619	membrane
KKR91_04055	COG0039	L-malate dehydrogenase activity
KKR91_04060	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KKR91_04070	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KKR91_04075	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KKR91_04080	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KKR91_04095	COG3842	ATPase activity
KKR91_04100	COG1176	ABC-type spermidine putrescine transport system, permease component I
KKR91_04105	COG1177	transmembrane transport
KKR91_04115	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KKR91_04125	COG2323	membrane
KKR91_04130	COG1278	Cold shock
KKR91_04135	COG2066	Belongs to the glutaminase family
KKR91_04135	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
KKR91_04140	COG1278	Cold shock
KKR91_04145	COG0747	negative chemotaxis
KKR91_04150	COG0601	transmembrane transport
KKR91_04155	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KKR91_04180	COG0515	serine threonine protein kinase
KKR91_04180	COG2815	serine threonine protein kinase
KKR91_04190	COG3012	SEC-C Motif Domain Protein
KKR91_04195	COG1063	alcohol dehydrogenase
KKR91_04200	COG1063	alcohol dehydrogenase
KKR91_04205	COG1174	glycine betaine transport
KKR91_04215	COG1174	glycine betaine transport
KKR91_04230	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
KKR91_04235	COG0829	nickel cation binding
KKR91_04240	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
KKR91_04250	COG0804	urea catabolic process
KKR91_04255	COG0832	Belongs to the urease beta subunit family
KKR91_04280	COG0753	catalase activity
KKR91_04345	COG0477	Major facilitator Superfamily
KKR91_04350	COG0138	bifunctional purine biosynthesis protein purh
KKR91_04400	COG4213	ABC transporter substrate-binding protein
KKR91_04405	COG4214	carbohydrate transport
KKR91_04435	COG2072	flavoprotein involved in K transport
KKR91_04440	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KKR91_04445	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KKR91_04450	COG1131	(ABC) transporter
KKR91_04485	COG0180	Tryptophanyl-tRNA synthetase
KKR91_04500	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KKR91_04515	COG2009	succinate dehydrogenase
KKR91_04520	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
KKR91_04520	COG0662	Cupin 2, conserved barrel domain protein
KKR91_04525	COG1473	amidohydrolase
KKR91_04525	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
KKR91_04530	COG1744	ABC transporter substrate-binding protein PnrA-like
KKR91_04535	COG3845	ABC transporter
KKR91_04540	COG4603	Belongs to the binding-protein-dependent transport system permease family
KKR91_04545	COG1079	Belongs to the binding-protein-dependent transport system permease family
KKR91_04565	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KKR91_04570	COG3956	TIGRFAM MazG family protein
KKR91_04575	COG0148	phosphopyruvate hydratase activity
KKR91_04595	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KKR91_04610	COG1609	Transcriptional regulator
KKR91_04615	COG1129	ABC transporter
KKR91_04620	COG1172	Belongs to the binding-protein-dependent transport system permease family
KKR91_04625	COG1879	ABC-type sugar transport system periplasmic component
KKR91_04630	COG1869	D-ribose catabolic process
KKR91_04635	COG0683	leucine binding
KKR91_04680	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KKR91_04685	COG0705	Rhomboid family
KKR91_04690	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KKR91_04700	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KKR91_04710	COG1331	Highly conserved protein containing a thioredoxin domain
KKR91_04720	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KKR91_04725	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KKR91_04740	COG1051	belongs to the nudix hydrolase family
KKR91_04745	COG0477	Major facilitator Superfamily
KKR91_04755	COG0114	fumarate hydratase activity
KKR91_04760	COG0288	reversible hydration of carbon dioxide
KKR91_04770	COG1494	fructose-1,6-bisphosphatase
KKR91_04790	COG1482	cell wall glycoprotein biosynthetic process
KKR91_04795	COG1316	TRANSCRIPTIONal
KKR91_04850	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
KKR91_04875	COG1022	Amp-dependent synthetase and ligase
KKR91_04905	COG0714	Associated with various cellular activities
KKR91_04910	COG0084	hydrolase, TatD family'
KKR91_04915	COG3583	domain protein
KKR91_04925	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KKR91_04930	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KKR91_04935	COG0488	(ABC) transporter
KKR91_04955	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KKR91_04960	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KKR91_04965	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
KKR91_04970	COG0193	aminoacyl-tRNA hydrolase activity
KKR91_05005	COG0822	iron-sulfur transferase activity
KKR91_05030	COG0745	RESPONSE REGULATOR receiver
KKR91_05040	COG5002	protein histidine kinase activity
KKR91_05075	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
KKR91_05105	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KKR91_05125	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KKR91_05140	COG0477	Major facilitator Superfamily
KKR91_05145	COG4770	biotin carboxylase activity
KKR91_05155	COG0424	maF-like protein
KKR91_05160	COG1823	symporter activity
KKR91_05175	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KKR91_05185	COG1028	Short-chain dehydrogenase reductase Sdr
KKR91_05205	COG0631	protein serine/threonine phosphatase activity
KKR91_05210	COG1674	ftsk spoiiie
KKR91_05235	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KKR91_05240	COG0483	inositol monophosphate 1-phosphatase activity
KKR91_05255	COG0456	acetyltransferase
KKR91_05260	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KKR91_05265	COG0154	amidase activity
KKR91_05270	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KKR91_05295	COG1254	Belongs to the acylphosphatase family
KKR91_05300	COG2986	histidine ammonia-lyase
KKR91_05310	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
KKR91_05325	COG1228	amidohydrolase
KKR91_05340	COG3250	beta-galactosidase activity
KKR91_05355	COG2873	o-acetylhomoserine
KKR91_05360	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KKR91_05390	COG0423	glycine-tRNA ligase activity
KKR91_05425	COG0358	DNA primase activity
KKR91_05445	COG0477	Major facilitator Superfamily
KKR91_05465	COG0297	glycogen (starch) synthase activity
KKR91_05475	COG1960	acyl-CoA dehydrogenase activity
KKR91_05485	COG0052	Belongs to the universal ribosomal protein uS2 family
KKR91_05490	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KKR91_05495	COG0528	UMP kinase activity
KKR91_05505	COG0233	cytoplasmic translational termination
KKR91_05520	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KKR91_05535	COG3275	phosphorelay sensor kinase activity
KKR91_05545	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KKR91_05560	COG0022	dehydrogenase e1 component
KKR91_05565	COG0508	dehydrogenase complex catalyzes the overall conversion of
KKR91_05575	COG1309	transcriptional regulator
KKR91_05580	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KKR91_05590	COG1960	acyl-CoA dehydrogenase activity
KKR91_05620	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KKR91_05625	COG0750	zinc metalloprotease
KKR91_05645	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
KKR91_05665	COG0442	prolyl-tRNA aminoacylation
KKR91_05675	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
KKR91_05690	COG0779	Required for maturation of 30S ribosomal subunits
KKR91_05705	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KKR91_05710	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KKR91_05720	COG0436	Aminotransferase
KKR91_05725	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KKR91_05750	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KKR91_05755	COG1185	polyribonucleotide nucleotidyltransferase activity
KKR91_05760	COG0612	Peptidase, M16
KKR91_05790	COG2365	Tyrosine phosphatase family
KKR91_05805	COG0521	Mo-molybdopterin cofactor biosynthetic process
KKR91_05815	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
KKR91_05830	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KKR91_05835	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KKR91_05840	COG1674	ftsk spoiiie
KKR91_05850	COG1546	Belongs to the CinA family
KKR91_05850	COG1058	Belongs to the CinA family
KKR91_05855	COG1396	sequence-specific DNA binding
KKR91_05870	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KKR91_05875	COG2137	regulation of response to DNA damage stimulus
KKR91_05890	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KKR91_05895	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KKR91_05900	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KKR91_05905	COG2813	Specifically methylates the guanine in position
KKR91_05910	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KKR91_05920	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KKR91_05930	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KKR91_05935	COG0131	Imidazoleglycerol-phosphate dehydratase
KKR91_05940	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KKR91_05950	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KKR91_05975	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KKR91_05980	COG0291	Belongs to the bacterial ribosomal protein bL35 family
KKR91_05985	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KKR91_05990	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KKR91_06000	COG2814	Major facilitator Superfamily
KKR91_06005	COG0494	nUDIX hydrolase
KKR91_06020	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KKR91_06025	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KKR91_06025	COG0072	phenylalanine-tRNA ligase activity
KKR91_06070	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KKR91_06075	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KKR91_06080	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KKR91_06085	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KKR91_06090	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KKR91_06095	COG1438	arginine binding
KKR91_06100	COG0137	argininosuccinate synthase activity
KKR91_06105	COG0165	Argininosuccinate lyase
KKR91_06110	COG0259	pyridoxamine-phosphate oxidase activity
KKR91_06130	COG2094	Belongs to the DNA glycosylase MPG family
KKR91_06140	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KKR91_06150	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KKR91_06180	COG0647	UMP catabolic process
KKR91_06195	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KKR91_06200	COG0497	DNA recombination
KKR91_06205	COG0504	CTP synthase activity
KKR91_06230	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KKR91_06235	COG2079	MmgE PrpD family protein
KKR91_06265	COG2197	response regulator
KKR91_06270	COG4585	Histidine kinase
KKR91_06280	COG4565	transcriptional regulatory protein
KKR91_06285	COG3290	protein histidine kinase activity
KKR91_06290	COG1301	dicarboxylic acid transport
KKR91_06300	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KKR91_06305	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KKR91_06320	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
KKR91_06325	COG1160	GTP binding
KKR91_06345	COG2197	response regulator
KKR91_06370	COG1028	Short-chain dehydrogenase reductase Sdr
KKR91_06380	COG2133	pyrroloquinoline quinone binding
KKR91_06395	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KKR91_06415	COG1716	ATPase activity
KKR91_06440	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
KKR91_06455	COG1940	carbohydrate kinase activity
KKR91_06475	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
KKR91_06480	COG2815	serine threonine protein kinase
KKR91_06480	COG0515	serine threonine protein kinase
KKR91_06485	COG3942	CHAP domain
KKR91_06485	COG1388	LysM domain
KKR91_06495	COG0142	geranyltranstransferase activity
KKR91_06505	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KKR91_06515	COG2001	Belongs to the MraZ family
KKR91_06520	COG0275	rRNA processing
KKR91_06530	COG0768	penicillin binding
KKR91_06535	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KKR91_06545	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KKR91_06550	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KKR91_06560	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KKR91_06565	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KKR91_06575	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KKR91_06580	COG1496	oxidoreductase activity
KKR91_06590	COG1799	cell septum assembly
KKR91_06605	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KKR91_06615	COG0587	DNA-directed DNA polymerase activity
KKR91_06630	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KKR91_06635	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KKR91_06660	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
KKR91_06665	COG0174	glutamine synthetase
KKR91_06670	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
KKR91_06675	COG0765	amino acid transport
KKR91_06680	COG1126	abc transporter atp-binding protein
KKR91_06715	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KKR91_06720	COG0321	lipoyl(octanoyl) transferase activity
KKR91_06730	COG4946	Tricorn protease homolog
KKR91_06730	COG0793	Belongs to the peptidase S41A family
KKR91_06735	COG1764	response to oxidative stress
KKR91_06745	COG0508	dehydrogenase complex catalyzes the overall conversion of
KKR91_06750	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KKR91_06755	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KKR91_06775	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KKR91_06785	COG0187	DNA topoisomerase II activity
KKR91_06800	COG1271	oxidase subunit
KKR91_06805	COG1294	oxidase, subunit
KKR91_06810	COG4988	ABC transporter
KKR91_06830	COG1064	alcohol dehydrogenase
KKR91_06835	COG1309	transcriptional regulator
KKR91_06840	COG1937	Protein conserved in bacteria
KKR91_06855	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KKR91_06875	COG1435	thymidine kinase activity
KKR91_06895	COG0756	dUTP diphosphatase activity
KKR91_06920	COG0569	domain protein
KKR91_06925	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KKR91_06930	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KKR91_06935	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KKR91_06950	COG0667	Aldo Keto reductase
KKR91_06960	COG1250	3-hydroxyacyl-CoA dehydrogenase
KKR91_06960	COG1024	Enoyl-CoA hydratase
KKR91_06965	COG0183	Belongs to the thiolase family
KKR91_07095	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KKR91_07100	COG0183	Belongs to the thiolase family
KKR91_07135	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
KKR91_07155	COG1269	ATP hydrolysis coupled proton transport
KKR91_07180	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KKR91_07195	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KKR91_07270	COG0242	peptide deformylase activity
KKR91_07275	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KKR91_07285	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KKR91_07305	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KKR91_07305	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KKR91_07310	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
KKR91_07350	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
KKR91_07350	COG3608	succinylglutamate desuccinylase aspartoacylase
KKR91_07390	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KKR91_07415	COG0640	Transcriptional regulator
KKR91_07420	COG0477	Major facilitator Superfamily
KKR91_07425	COG3896	Chloramphenicol phosphotransferase-like protein
KKR91_07445	COG4221	oxidoreductase activity
KKR91_07480	COG2314	TM2 domain
KKR91_07485	COG0140	phosphoribosyl-ATP diphosphatase activity
KKR91_07490	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KKR91_07495	COG0107	imidazoleglycerol-phosphate synthase activity
KKR91_07505	COG2814	Major facilitator Superfamily
KKR91_07520	COG1064	alcohol dehydrogenase
KKR91_07560	COG2354	Protein conserved in bacteria
KKR91_07570	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KKR91_07590	COG0134	indole-3-glycerol-phosphate synthase activity
KKR91_07595	COG0133	tryptophan synthase activity
KKR91_07600	COG0159	tryptophan synthase activity
KKR91_07605	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KKR91_07610	COG0067	glutamate synthase
KKR91_07610	COG0069	glutamate synthase activity
KKR91_07610	COG0070	glutamate synthase
KKR91_07630	COG0469	pyruvate kinase activity
KKR91_07655	COG3415	Transposase
KKR91_07655	COG2801	Transposase and inactivated derivatives
KKR91_07665	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KKR91_07670	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
KKR91_07700	COG0385	Bile acid
KKR91_07715	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KKR91_07800	COG0456	acetyltransferase
KKR91_07835	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KKR91_07855	COG0789	Transcriptional regulator
KKR91_07865	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KKR91_07880	COG2814	Major facilitator Superfamily
KKR91_07955	COG3547	Transposase (IS116 IS110 IS902 family)
KKR91_08025	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
KKR91_08035	COG0778	Nitroreductase
KKR91_08060	COG1132	(ABC) transporter
KKR91_08080	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KKR91_08110	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KKR91_08115	COG5002	protein histidine kinase activity
KKR91_08125	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KKR91_08135	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KKR91_08160	COG1012	belongs to the aldehyde dehydrogenase family
KKR91_08175	COG3226	Transcriptional regulator
KKR91_08180	COG1228	amidohydrolase
KKR91_08215	COG1902	pentaerythritol trinitrate reductase activity
KKR91_08225	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KKR91_08240	COG1126	abc transporter atp-binding protein
KKR91_08290	COG1185	polyribonucleotide nucleotidyltransferase activity
KKR91_08330	COG1802	Transcriptional regulator
KKR91_08335	COG1012	belongs to the aldehyde dehydrogenase family
KKR91_08345	COG3971	2-oxopent-4-enoate hydratase activity
KKR91_08355	COG0477	Major facilitator Superfamily
KKR91_08370	COG1028	Short-chain dehydrogenase reductase Sdr
KKR91_08395	COG1846	Transcriptional regulator
KKR91_08400	COG5650	phosphatidylinositol metabolic process
KKR91_08405	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KKR91_08425	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KKR91_08435	COG2808	Putative FMN-binding domain
KKR91_08470	COG2890	protein-(glutamine-N5) methyltransferase activity
KKR91_08485	COG1643	Atp-dependent helicase
KKR91_08495	COG0745	RESPONSE REGULATOR receiver
KKR91_08500	COG2205	protein histidine kinase activity
KKR91_08520	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KKR91_08525	COG2197	response regulator
KKR91_08535	COG0577	efflux transmembrane transporter activity
KKR91_08535	COG1136	(ABC) transporter
KKR91_08545	COG2814	Major facilitator Superfamily
KKR91_08570	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KKR91_08575	COG1028	Short-chain dehydrogenase reductase Sdr
KKR91_08585	COG1028	Short-chain dehydrogenase reductase Sdr
KKR91_08590	COG1028	Short-chain dehydrogenase reductase Sdr
KKR91_08600	COG0535	radical SAM domain protein
KKR91_08630	COG1960	acyl-CoA dehydrogenase activity
KKR91_08645	COG0488	(ABC) transporter
KKR91_08655	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KKR91_08675	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
KKR91_08685	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
KKR91_08720	COG0009	L-threonylcarbamoyladenylate synthase
KKR91_08735	COG1028	Short-chain dehydrogenase reductase Sdr
KKR91_08745	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KKR91_08755	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KKR91_08760	COG2261	transglycosylase associated protein
KKR91_08765	COG0366	Alpha amylase catalytic
KKR91_08775	COG1793	dna ligase
KKR91_08775	COG3285	dna ligase
KKR91_08785	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
KKR91_08790	COG1215	transferase activity, transferring glycosyl groups
KKR91_08810	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KKR91_08815	COG0471	metal ion transport
KKR91_08820	COG0473	3-isopropylmalate dehydrogenase activity
KKR91_08830	COG0697	spore germination
KKR91_08845	COG0542	response to heat
KKR91_08855	COG1063	alcohol dehydrogenase
KKR91_08875	COG1335	isochorismatase
KKR91_08890	COG4941	Belongs to the sigma-70 factor family
KKR91_08915	COG0242	peptide deformylase activity
KKR91_08920	COG1506	peptidase
KKR91_08920	COG4946	Tricorn protease homolog
KKR91_08920	COG0823	Involved in the tonB-independent uptake of proteins
KKR91_08945	COG1216	Glycosyl transferase, family 2
KKR91_08950	COG1574	metal-dependent hydrolase with the TIM-barrel fold
KKR91_08955	COG4581	dead DEAH box helicase
KKR91_08960	COG0805	protein transport
KKR91_08965	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KKR91_08985	COG0545	Peptidyl-prolyl cis-trans isomerase
KKR91_08990	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
KKR91_08995	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
KKR91_09000	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
KKR91_09010	COG4122	O-methyltransferase activity
KKR91_09015	COG1222	aaa ATPase
KKR91_09025	COG0517	IMP dehydrogenase activity
KKR91_09025	COG1994	Peptidase M50
KKR91_09030	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KKR91_09040	COG0215	cysteine-tRNA ligase activity
KKR91_09045	COG1968	undecaprenyl-diphosphatase activity
KKR91_09065	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KKR91_09080	COG1253	flavin adenine dinucleotide binding
KKR91_09090	COG0589	response to stress
KKR91_09110	COG0183	Belongs to the thiolase family
KKR91_09125	COG0297	glycogen (starch) synthase activity
KKR91_09130	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KKR91_09140	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KKR91_09145	COG2855	membrane
KKR91_09170	COG0254	rRNA binding
KKR91_09195	COG1119	ATPase activity
KKR91_09200	COG0560	Phosphoserine phosphatase
KKR91_09200	COG3830	Belongs to the UPF0237 family
KKR91_09205	COG1028	Short-chain dehydrogenase reductase Sdr
KKR91_09255	COG0488	(ABC) transporter
KKR91_09260	COG1268	BioY protein
KKR91_09265	COG1122	ATPase activity
KKR91_09285	COG2151	metal-sulfur cluster biosynthetic enzyme
KKR91_09290	COG0396	ATPase activity
KKR91_09310	COG1131	(ABC) transporter
KKR91_09325	COG0109	protoheme IX farnesyltransferase activity
KKR91_09335	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KKR91_09340	COG0166	Belongs to the GPI family
KKR91_09355	COG0363	glucosamine-6-phosphate deaminase activity
KKR91_09360	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KKR91_09365	COG0149	triose-phosphate isomerase activity
KKR91_09370	COG0126	phosphoglycerate kinase activity
KKR91_09385	COG1481	regulation of sporulation
KKR91_09395	COG1660	Displays ATPase and GTPase activities
KKR91_09400	COG0322	excinuclease ABC activity
KKR91_09435	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KKR91_09440	COG0531	amino acid
KKR91_09445	COG4106	trans-aconitate 2-methyltransferase activity
KKR91_09455	COG0456	acetyltransferase
KKR91_09495	COG0556	nucleotide-excision repair
KKR91_09500	COG0237	dephospho-CoA kinase activity
KKR91_09500	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KKR91_09505	COG1739	Uncharacterized protein family UPF0029
KKR91_09510	COG2890	protein-(glutamine-N5) methyltransferase activity
KKR91_09535	COG2723	6-phospho-beta-galactosidase activity
KKR91_09545	COG0539	negative regulation of cytoplasmic translation
KKR91_09555	COG2050	protein possibly involved in aromatic compounds catabolism
KKR91_09585	COG2814	Major facilitator Superfamily
KKR91_09595	COG0076	glutamate decarboxylase activity
KKR91_09600	COG0531	amino acid
KKR91_09610	COG1414	Transcriptional regulator
KKR91_09615	COG1082	Xylose isomerase domain protein TIM barrel
KKR91_09615	COG3185	4-Hydroxyphenylpyruvate dioxygenase
KKR91_09620	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KKR91_09635	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KKR91_09640	COG1472	Belongs to the glycosyl hydrolase 3 family
KKR91_09650	COG1607	acyl-coa hydrolase
KKR91_09675	COG2272	Belongs to the type-B carboxylesterase lipase family
KKR91_09690	COG0488	(ABC) transporter
KKR91_09715	COG1846	Transcriptional regulator
KKR91_09720	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KKR91_09725	COG1024	Enoyl-CoA hydratase
KKR91_09730	COG1012	belongs to the aldehyde dehydrogenase family
KKR91_09745	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KKR91_09750	COG1960	acyl-CoA dehydrogenase activity
KKR91_09755	COG2391	methyltransferase activity
KKR91_09760	COG0425	Belongs to the sulfur carrier protein TusA family
KKR91_09770	COG1309	transcriptional regulator
KKR91_09785	COG1028	Short-chain dehydrogenase reductase Sdr
KKR91_09800	COG1136	(ABC) transporter
KKR91_09820	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KKR91_09825	COG1845	cytochrome c oxidase, subunit III
KKR91_09830	COG2010	Cytochrome c
KKR91_09835	COG0723	plastoquinol--plastocyanin reductase activity
KKR91_09840	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KKR91_09850	COG2188	Transcriptional regulator
KKR91_09860	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KKR91_09865	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KKR91_09885	COG0167	dihydroorotate dehydrogenase activity
KKR91_09895	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KKR91_09900	COG1381	Involved in DNA repair and RecF pathway recombination
KKR91_09905	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KKR91_09910	COG1316	TRANSCRIPTIONal
KKR91_09915	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KKR91_09925	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KKR91_09945	COG0484	heat shock protein binding
KKR91_09950	COG1420	regulation of RNA biosynthetic process
KKR91_09970	COG0481	GTPase activity
KKR91_09980	COG0268	Binds directly to 16S ribosomal RNA
KKR91_10020	COG1555	photosystem II stabilization
KKR91_10020	COG1596	polysaccharide export
KKR91_10025	COG1307	EDD domain protein, DegV family
KKR91_10030	COG0495	leucyl-tRNA aminoacylation
KKR91_10035	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KKR91_10040	COG1595	DNA-templated transcription, initiation
KKR91_10045	COG1088	dTDP-glucose 4,6-dehydratase activity
KKR91_10050	COG0385	Bile acid
KKR91_10055	COG2072	flavoprotein involved in K transport
KKR91_10060	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KKR91_10065	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KKR91_10085	COG2130	NADP-dependent
KKR91_10090	COG1846	Transcriptional regulator
KKR91_10095	COG0842	Transport permease protein
KKR91_10095	COG1129	ABC transporter
KKR91_10115	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KKR91_10125	COG1758	RNA polymerase activity
KKR91_10130	COG0194	GDP metabolic process
KKR91_10135	COG0194	GDP metabolic process
KKR91_10140	COG0284	orotidine-5'-phosphate decarboxylase activity
KKR91_10145	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KKR91_10150	COG0505	Belongs to the CarA family
KKR91_10160	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KKR91_10165	COG0540	Belongs to the ATCase OTCase family
KKR91_10170	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KKR91_10180	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KKR91_10185	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KKR91_10190	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KKR91_10195	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KKR91_10200	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KKR91_10205	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KKR91_10215	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KKR91_10220	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KKR91_10235	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KKR91_10255	COG0384	phenazine biosynthesis protein PhzF
KKR91_10270	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KKR91_10280	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KKR91_10295	COG2197	response regulator
KKR91_10300	COG0124	histidyl-tRNA synthetase
KKR91_10310	COG1196	nuclear chromosome segregation
KKR91_10320	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KKR91_10325	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KKR91_10330	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KKR91_10340	COG2255	four-way junction helicase activity
KKR91_10345	COG0632	four-way junction helicase activity
KKR91_10350	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
KKR91_10355	COG0217	transcriptional regulatory protein
KKR91_10360	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KKR91_10370	COG2197	response regulator
KKR91_10395	COG2376	Dihydroxyacetone kinase
KKR91_10405	COG0339	signal peptide processing
KKR91_10415	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KKR91_10425	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KKR91_10430	COG0587	DNA-directed DNA polymerase activity
KKR91_10455	COG1804	L-carnitine dehydratase bile acid-inducible protein F
KKR91_10465	COG2409	Drug exporters of the RND superfamily
KKR91_10485	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KKR91_10500	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KKR91_10530	COG0656	L-ascorbic acid biosynthetic process
KKR91_10540	COG2135	peptidase activity
KKR91_10580	COG1028	Short-chain dehydrogenase reductase Sdr
KKR91_10610	COG1819	glycosyl
KKR91_10620	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KKR91_10630	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KKR91_10635	COG1780	Probably involved in ribonucleotide reductase function
KKR91_10645	COG0583	DNA-binding transcription factor activity
KKR91_10710	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KKR91_10720	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KKR91_10725	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KKR91_10730	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KKR91_10735	COG0211	Belongs to the bacterial ribosomal protein bL27 family
KKR91_10740	COG0261	This protein binds to 23S rRNA in the presence of protein L20
KKR91_10745	COG1530	ribonuclease E activity
KKR91_10765	COG0105	UTP biosynthetic process
KKR91_10775	COG0285	dihydrofolate synthase activity
KKR91_10780	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KKR91_10795	COG4221	oxidoreductase activity
KKR91_10805	COG0525	valine-tRNA ligase activity
KKR91_10810	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KKR91_10815	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KKR91_10820	COG0740	serine-type endopeptidase activity
KKR91_10830	COG0544	peptidyl-prolyl cis-trans isomerase activity
KKR91_10850	COG0698	ribose 5-phosphate isomerase
KKR91_10875	COG0668	transmembrane transport
KKR91_10895	COG1946	Acyl-CoA thioesterase
KKR91_10910	COG0629	single-stranded DNA binding
KKR91_10980	COG0242	peptide deformylase activity
KKR91_11000	COG3022	response to hydroperoxide
KKR91_11010	COG1579	Zn-ribbon protein possibly nucleic acid-binding
KKR91_11015	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KKR91_11020	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KKR91_11030	COG1045	serine acetyltransferase
KKR91_11035	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KKR91_11065	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
KKR91_11070	COG2186	Transcriptional regulator
KKR91_11100	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KKR91_11105	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KKR91_11110	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KKR91_11120	COG4974	Belongs to the 'phage' integrase family
KKR91_11140	COG0792	nuclease activity
KKR91_11170	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KKR91_11180	COG0681	Belongs to the peptidase S26 family
KKR91_11185	COG0335	large ribosomal subunit rRNA binding
KKR91_11190	COG0336	Belongs to the RNA methyltransferase TrmD family
KKR91_11195	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KKR91_11200	COG1837	Belongs to the UPF0109 family
KKR91_11205	COG0228	four-way junction DNA binding
KKR91_11210	COG2514	catechol 2,3-dioxygenase activity
KKR91_11230	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KKR91_11255	COG0477	Major facilitator Superfamily
KKR91_11270	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KKR91_11275	COG0318	PFAM AMP-dependent synthetase and ligase
KKR91_11280	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KKR91_11285	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KKR91_11290	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KKR91_11300	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KKR91_11320	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KKR91_11335	COG0742	ribosomal rna small subunit methyltransferase
KKR91_11345	COG1461	Dihydroxyacetone kinase
KKR91_11355	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KKR91_11375	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KKR91_11380	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KKR91_11385	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KKR91_11390	COG1215	transferase activity, transferring glycosyl groups
KKR91_11390	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KKR91_11395	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KKR91_11400	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KKR91_11410	COG1134	teichoic acid transport
KKR91_11415	COG1682	transport, permease protein
KKR91_11440	COG1181	Belongs to the D-alanine--D-alanine ligase family
KKR91_11445	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
KKR91_11455	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KKR91_11460	COG0066	3-isopropylmalate dehydratase activity
KKR91_11465	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KKR91_11470	COG1414	Transcriptional regulator
KKR91_11475	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KKR91_11495	COG1011	Hydrolase
KKR91_11500	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KKR91_11510	COG0179	Fumarylacetoacetate (FAA) hydrolase
KKR91_11540	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KKR91_11545	COG0473	3-isopropylmalate dehydrogenase activity
KKR91_11550	COG4585	Histidine kinase
KKR91_11555	COG2197	response regulator
KKR91_11565	COG0577	efflux transmembrane transporter activity
KKR91_11565	COG1136	(ABC) transporter
KKR91_11570	COG0577	efflux transmembrane transporter activity
KKR91_11570	COG1136	(ABC) transporter
KKR91_11590	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KKR91_11595	COG0440	acetolactate synthase activity
KKR91_11605	COG0129	dihydroxy-acid dehydratase activity
KKR91_11655	COG0747	negative chemotaxis
KKR91_11660	COG0601	transmembrane transport
KKR91_11665	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KKR91_11675	COG0747	negative chemotaxis
KKR91_11680	COG0579	oxidoreductase
KKR91_11685	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KKR91_11690	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KKR91_11700	COG1028	Short-chain dehydrogenase reductase Sdr
KKR91_11705	COG2814	Major facilitator Superfamily
KKR91_11710	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KKR91_11720	COG1113	amino acid transport
KKR91_11730	COG0515	serine threonine protein kinase
KKR91_11745	COG0419	ATPase involved in DNA repair
KKR91_11750	COG0420	3'-5' exonuclease activity
KKR91_11755	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KKR91_11770	COG0586	Pfam SNARE associated Golgi protein
KKR91_11775	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KKR91_11780	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KKR91_11795	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KKR91_11805	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
KKR91_11815	COG1335	isochorismatase
KKR91_11840	COG1131	(ABC) transporter
KKR91_11845	COG1902	pentaerythritol trinitrate reductase activity
KKR91_11870	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
KKR91_11880	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KKR91_11890	COG0355	proton-transporting ATP synthase activity, rotational mechanism
KKR91_11895	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KKR91_11900	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KKR91_11905	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KKR91_11910	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KKR91_11915	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KKR91_11920	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KKR91_11925	COG0356	it plays a direct role in the translocation of protons across the membrane
KKR91_11940	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KKR91_11945	COG1086	Polysaccharide biosynthesis protein
KKR91_11955	COG1216	Glycosyl transferase, family 2
KKR91_11970	COG2890	protein-(glutamine-N5) methyltransferase activity
KKR91_11975	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KKR91_11985	COG0083	homoserine kinase activity
KKR91_11990	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KKR91_11995	COG0460	homoserine dehydrogenase
KKR91_12005	COG0018	arginyl-trna synthetase
KKR91_12020	COG1017	nitric oxide dioxygenase activity
KKR91_12020	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KKR91_12030	COG2801	Transposase and inactivated derivatives
KKR91_12030	COG3415	Transposase
KKR91_12035	COG0028	Belongs to the TPP enzyme family
KKR91_12055	COG0410	ABC transporter
KKR91_12105	COG1643	Atp-dependent helicase
KKR91_12130	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KKR91_12135	COG1121	(ABC) transporter
KKR91_12150	COG1253	flavin adenine dinucleotide binding
KKR91_12155	COG0508	dehydrogenase complex catalyzes the overall conversion of
KKR91_12155	COG0567	Dehydrogenase, E1 component
KKR91_12165	COG0747	negative chemotaxis
KKR91_12175	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KKR91_12180	COG4172	Belongs to the ABC transporter superfamily
KKR91_12190	COG1595	DNA-templated transcription, initiation
KKR91_12200	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
KKR91_12210	COG0483	inositol monophosphate 1-phosphatase activity
KKR91_12220	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KKR91_12225	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KKR91_12230	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
KKR91_12240	COG0366	Alpha amylase catalytic
KKR91_12265	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KKR91_12275	COG2177	Part of the ABC transporter FtsEX involved in
KKR91_12280	COG2884	Cell division ATP-binding protein ftsE
KKR91_12285	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KKR91_12305	COG1215	transferase activity, transferring glycosyl groups
KKR91_12335	COG1876	peptidase activity
KKR91_12365	COG1086	Polysaccharide biosynthesis protein
KKR91_12370	COG0463	Glycosyl transferase, family 2
KKR91_12405	COG1216	Glycosyl transferase, family 2
KKR91_12435	COG2902	Dehydrogenase
KKR91_12470	COG0653	protein targeting
KKR91_12475	COG3214	Protein conserved in bacteria
KKR91_12480	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KKR91_12485	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KKR91_12490	COG5401	PFAM Sporulation and spore germination
KKR91_12495	COG5002	protein histidine kinase activity
KKR91_12500	COG0745	RESPONSE REGULATOR receiver
KKR91_12520	COG0714	Associated with various cellular activities
KKR91_12545	COG0482	sulfurtransferase activity
KKR91_12560	COG0484	heat shock protein binding
KKR91_12565	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KKR91_12570	COG4106	trans-aconitate 2-methyltransferase activity
KKR91_12575	COG1595	DNA-templated transcription, initiation
KKR91_12585	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KKR91_12590	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
KKR91_12600	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KKR91_12610	COG1842	Phage shock protein A
KKR91_12625	COG1615	UPF0182 protein
KKR91_12630	COG3480	Lon protease (S16) C-terminal proteolytic domain
KKR91_12670	COG1131	(ABC) transporter
KKR91_12680	COG0210	DNA helicase
KKR91_12700	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KKR91_12705	COG2011	ABC-type metal ion transport system permease component
KKR91_12710	COG1464	Belongs to the NlpA lipoprotein family
KKR91_12715	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KKR91_12720	COG0113	porphobilinogen synthase activity
KKR91_12730	COG0181	hydroxymethylbilane synthase activity
KKR91_12735	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KKR91_12740	COG3253	May function as heme-dependent peroxidase
KKR91_12745	COG1231	oxidoreductase activity
KKR91_12750	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KKR91_12755	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KKR91_12790	COG0513	Belongs to the DEAD box helicase family
KKR91_12800	COG0613	PHP domain protein
KKR91_12805	COG0006	proline dipeptidase activity
KKR91_12815	COG2239	Acts as a magnesium transporter
KKR91_12830	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KKR91_12840	COG1595	DNA-templated transcription, initiation
KKR91_12845	COG4122	O-methyltransferase activity
KKR91_12850	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KKR91_12865	COG2818	Glycosylase
KKR91_12875	COG1611	Belongs to the LOG family
KKR91_12880	COG1126	abc transporter atp-binding protein
KKR91_12885	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KKR91_12890	COG0765	amino acid transport
KKR91_12895	COG0765	amino acid transport
KKR91_12900	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KKR91_12905	COG2171	N-acyltransferase activity
KKR91_12915	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KKR91_12945	COG1217	gtp-binding protein TYPA
KKR91_12955	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KKR91_12960	COG0601	transmembrane transport
KKR91_12970	COG0747	negative chemotaxis
KKR91_13035	COG0012	GTP binding
KKR91_13040	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KKR91_13050	COG1570	exodeoxyribonuclease VII activity
KKR91_13055	COG1722	exodeoxyribonuclease VII activity
KKR91_13075	COG1174	glycine betaine transport
KKR91_13090	COG2971	BadF BadG BcrA BcrD
KKR91_13125	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KKR91_13130	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KKR91_13155	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KKR91_13155	COG0519	Catalyzes the synthesis of GMP from XMP
KKR91_13175	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KKR91_13180	COG0516	GMP reductase activity
KKR91_13190	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
KKR91_13190	COG2755	lipolytic protein G-D-S-L family
KKR91_13195	COG0459	protein refolding
KKR91_13200	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KKR91_13210	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KKR91_13215	COG4605	iron ion homeostasis
KKR91_13220	COG4604	ABC transporter, ATP-binding protein
KKR91_13225	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KKR91_13235	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KKR91_13240	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
KKR91_13250	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KKR91_13260	COG0456	acetyltransferase
KKR91_13260	COG1214	PFAM Peptidase M22, glycoprotease
KKR91_13265	COG0802	atpase or kinase
KKR91_13270	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KKR91_13275	COG0667	Aldo Keto reductase
KKR91_13300	COG0736	holo-[acyl-carrier-protein] synthase activity
KKR91_13305	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KKR91_13310	COG1072	(Pantothenic acid kinase))
KKR91_13315	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KKR91_13320	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
KKR91_13325	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KKR91_13330	COG0101	tRNA pseudouridine synthase activity
KKR91_13335	COG0203	ribosomal protein L17
KKR91_13340	COG0202	RNA polymerase activity
KKR91_13345	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KKR91_13350	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KKR91_13355	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KKR91_13360	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KKR91_13370	COG0563	adenylate kinase activity
KKR91_13380	COG0200	Binds to the 23S rRNA
KKR91_13385	COG1841	ribosomal large subunit assembly
KKR91_13390	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KKR91_13400	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KKR91_13405	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KKR91_13410	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KKR91_13415	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KKR91_13420	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KKR91_13425	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KKR91_13430	COG0255	Belongs to the universal ribosomal protein uL29 family
KKR91_13435	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KKR91_13440	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KKR91_13445	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KKR91_13450	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KKR91_13455	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KKR91_13460	COG0089	rRNA binding
KKR91_13465	COG0088	Forms part of the polypeptide exit tunnel
KKR91_13470	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KKR91_13475	COG0051	transcription antitermination factor activity, RNA binding
KKR91_13485	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KKR91_13490	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KKR91_13495	COG0049	tRNA binding
KKR91_13500	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KKR91_13505	COG1414	Transcriptional regulator
KKR91_13510	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KKR91_13520	COG0183	Belongs to the thiolase family
KKR91_13525	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KKR91_13540	COG3485	protocatechuate 3,4-dioxygenase
KKR91_13545	COG3485	protocatechuate 3,4-dioxygenase
KKR91_13555	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KKR91_13560	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KKR91_13565	COG0085	RNA polymerase activity
KKR91_13570	COG0183	Belongs to the thiolase family
KKR91_13575	COG0222	ribosome binding
KKR91_13580	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KKR91_13590	COG0081	regulation of translation
KKR91_13595	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KKR91_13605	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KKR91_13615	COG0436	Aminotransferase
KKR91_13620	COG2197	response regulator
KKR91_13660	COG0354	folic acid binding
KKR91_13665	COG3485	protocatechuate 3,4-dioxygenase
KKR91_13675	COG0745	RESPONSE REGULATOR receiver
KKR91_13680	COG0456	acetyltransferase
KKR91_13685	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KKR91_13705	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KKR91_13710	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KKR91_13715	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KKR91_13730	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KKR91_13740	COG2030	dehydratase
KKR91_13755	COG0693	protein deglycase activity
KKR91_13775	COG0515	serine threonine protein kinase
KKR91_13775	COG2815	serine threonine protein kinase
KKR91_13795	COG5650	phosphatidylinositol metabolic process
KKR91_13800	COG1228	amidohydrolase
KKR91_13830	COG1063	alcohol dehydrogenase
KKR91_13835	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KKR91_13850	COG1666	GTP binding
KKR91_13860	COG0501	Belongs to the peptidase M48B family
KKR91_13870	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KKR91_13910	COG1233	COG1233 Phytoene dehydrogenase and related
KKR91_13920	COG0142	geranyltranstransferase activity
KKR91_13925	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
KKR91_13950	COG0179	Fumarylacetoacetate (FAA) hydrolase
KKR91_13960	COG1028	Short-chain dehydrogenase reductase Sdr
KKR91_13965	COG1309	transcriptional regulator
KKR91_13975	COG1116	anion transmembrane transporter activity
KKR91_13980	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KKR91_13985	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KKR91_13995	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KKR91_14010	COG3971	2-oxopent-4-enoate hydratase activity
KKR91_14030	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KKR91_14065	COG2409	Drug exporters of the RND superfamily
KKR91_14110	COG0800	Aldolase
KKR91_14115	COG2721	sulfolactate sulfo-lyase activity
KKR91_14120	COG4948	Mandelate Racemase Muconate Lactonizing
KKR91_14130	COG1609	Transcriptional regulator
KKR91_14140	COG3842	ATPase activity
KKR91_14150	COG0395	ABC-type sugar transport system, permease component
KKR91_14155	COG0246	Mannitol dehydrogenase
KKR91_14225	COG0142	geranyltranstransferase activity
KKR91_14230	COG0644	oxidoreductase
KKR91_14235	COG2226	methyltransferase
KKR91_14245	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KKR91_14255	COG0765	amino acid transport
KKR91_14260	COG1126	abc transporter atp-binding protein
KKR91_14265	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
KKR91_14270	COG0028	Belongs to the TPP enzyme family
KKR91_14280	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KKR91_14285	COG1113	amino acid transport
KKR91_14295	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KKR91_14300	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KKR91_14325	COG0024	Methionine aminopeptidase
KKR91_14330	COG1937	Protein conserved in bacteria
KKR91_14360	COG0402	S-adenosylhomocysteine deaminase activity
KKR91_14370	COG0589	response to stress
KKR91_14380	COG4948	Mandelate Racemase Muconate Lactonizing
KKR91_14400	COG0508	dehydrogenase complex catalyzes the overall conversion of
KKR91_14405	COG0022	dehydrogenase e1 component
KKR91_14415	COG1522	sequence-specific DNA binding
KKR91_14425	COG2837	iron assimilation
KKR91_14450	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KKR91_14455	COG2151	metal-sulfur cluster biosynthetic enzyme
KKR91_14460	COG3396	Phenylacetate-CoA oxygenase
KKR91_14465	COG3460	Phenylacetate-CoA oxygenase
KKR91_14470	COG3396	Phenylacetate-CoA oxygenase
KKR91_14495	COG0586	Pfam SNARE associated Golgi protein
KKR91_14515	COG0628	permease
KKR91_14530	COG1012	belongs to the aldehyde dehydrogenase family
KKR91_14530	COG2030	dehydratase
KKR91_14540	COG1793	dna ligase
KKR91_14550	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KKR91_14560	COG2365	Tyrosine phosphatase family
KKR91_14570	COG1250	3-hydroxyacyl-CoA dehydrogenase
KKR91_14575	COG1024	Enoyl-CoA hydratase
KKR91_14590	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KKR91_14615	COG1140	nitrate reductase beta subunit
KKR91_14625	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KKR91_14650	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KKR91_14660	COG0785	Cytochrome C biogenesis protein
KKR91_14670	COG0406	alpha-ribazole phosphatase activity
KKR91_14675	COG2353	YceI-like domain
KKR91_14690	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KKR91_14715	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KKR91_14720	COG0640	Transcriptional regulator
KKR91_14725	COG0123	including yeast histone deacetylase and acetoin utilization protein
KKR91_14730	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KKR91_14735	COG0569	domain protein
KKR91_14745	COG1082	Xylose isomerase domain protein TIM barrel
KKR91_14750	COG0248	Ppx GppA phosphatase
KKR91_14755	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KKR91_14755	COG1754	DNA topoisomerase type I activity
KKR91_14760	COG2890	protein-(glutamine-N5) methyltransferase activity
KKR91_14765	COG1053	succinate dehydrogenase
KKR91_14770	COG1054	Belongs to the UPF0176 family
KKR91_14780	COG1205	dead DEAH box helicase
KKR91_14780	COG1111	helicase
KKR91_14825	COG2755	lipolytic protein G-D-S-L family
KKR91_14825	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
KKR91_14830	COG0494	nUDIX hydrolase
KKR91_14845	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KKR91_14850	COG1764	response to oxidative stress
KKR91_14860	COG0477	Major facilitator Superfamily
KKR91_14865	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
KKR91_14895	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KKR91_14900	COG1408	metallophosphoesterase
KKR91_14905	COG1132	(ABC) transporter
KKR91_14910	COG1132	(ABC) transporter
KKR91_14920	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
KKR91_14925	COG0151	Belongs to the GarS family
KKR91_14930	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KKR91_14955	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
KKR91_15005	COG0220	tRNA (guanine-N7-)-methyltransferase activity
KKR91_15025	COG1131	(ABC) transporter
KKR91_15035	COG0789	Transcriptional regulator
KKR91_15040	COG0484	heat shock protein binding
KKR91_15045	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KKR91_15050	COG0443	Heat shock 70 kDa protein
KKR91_15065	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KKR91_15075	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KKR91_15090	COG1122	ATPase activity
KKR91_15105	COG1320	monovalent cation:proton antiporter activity
KKR91_15110	COG2212	antiporter activity
KKR91_15120	COG0651	ATP synthesis coupled electron transport
KKR91_15125	COG1006	Multisubunit Na H antiporter MnhC subunit
KKR91_15130	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KKR91_15130	COG2111	Na H antiporter
KKR91_15140	COG0717	Belongs to the dCTP deaminase family
KKR91_15145	COG3483	tryptophan 2,3-dioxygenase activity
KKR91_15205	COG3336	cytochrome c oxidase
KKR91_15210	COG0776	regulation of translation
KKR91_15215	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KKR91_15220	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KKR91_15225	COG0227	Belongs to the bacterial ribosomal protein bL28 family
KKR91_15230	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KKR91_15240	COG0477	Major facilitator Superfamily
KKR91_15250	COG1597	lipid kinase activity
KKR91_15255	COG1196	nuclear chromosome segregation
KKR91_15255	COG0739	heme binding
KKR91_15255	COG0741	lytic transglycosylase activity
KKR91_15260	COG2375	cellular response to nickel ion
KKR91_15265	COG1120	ATPase activity
KKR91_15270	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KKR91_15275	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KKR91_15280	COG0435	Glutathione S-transferase
KKR91_15295	COG1295	ribonuclease BN
KKR91_15315	COG2146	nitrite reductase [NAD(P)H] activity
KKR91_15335	COG1028	Short-chain dehydrogenase reductase Sdr
KKR91_15350	COG1064	alcohol dehydrogenase
KKR91_15370	COG0531	amino acid
KKR91_15405	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
KKR91_15420	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
KKR91_15450	COG0183	Belongs to the thiolase family
KKR91_15455	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KKR91_15460	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KKR91_15475	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KKR91_15485	COG1960	acyl-CoA dehydrogenase activity
KKR91_15510	COG1309	transcriptional regulator
KKR91_15525	COG1172	Belongs to the binding-protein-dependent transport system permease family
KKR91_15540	COG1028	Short-chain dehydrogenase reductase Sdr
KKR91_15550	COG1960	acyl-CoA dehydrogenase activity
KKR91_15565	COG1476	TRANSCRIPTIONal
KKR91_15575	COG1473	amidohydrolase
KKR91_15580	COG4585	Histidine kinase
KKR91_15585	COG2197	response regulator
KKR91_15590	COG4152	abc transporter atp-binding protein
KKR91_15615	COG1028	Short-chain dehydrogenase reductase Sdr
KKR91_15650	COG1012	belongs to the aldehyde dehydrogenase family
KKR91_15665	COG0318	PFAM AMP-dependent synthetase and ligase
KKR91_15675	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
KKR91_15685	COG4221	oxidoreductase activity
KKR91_15705	COG0028	Belongs to the TPP enzyme family
KKR91_15715	COG0596	Alpha beta hydrolase
KKR91_15720	COG5002	protein histidine kinase activity
KKR91_15730	COG1012	belongs to the aldehyde dehydrogenase family
KKR91_15735	COG2860	membrane
KKR91_15775	COG0577	efflux transmembrane transporter activity
KKR91_15820	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KKR91_15845	COG3386	PFAM SMP-30 Gluconolaconase
KKR91_15850	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KKR91_15855	COG2076	Multidrug Resistance protein
KKR91_15865	COG0531	amino acid
KKR91_15910	COG0492	ferredoxin-NADP+ reductase activity
KKR91_15915	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KKR91_15920	COG0798	PFAM Bile acid sodium symporter
KKR91_15965	COG3559	Exporter of polyketide antibiotics
KKR91_15970	COG1131	(ABC) transporter
KKR91_16020	COG2217	Heavy metal translocating P-type atpase
KKR91_16025	COG0598	Magnesium transport protein CorA
KKR91_16040	COG0477	Major facilitator Superfamily
KKR91_16045	COG3546	catalase activity
KKR91_16070	COG1028	Short-chain dehydrogenase reductase Sdr
KKR91_16075	COG2814	Major facilitator Superfamily
KKR91_16085	COG0477	Major facilitator Superfamily
KKR91_16095	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KKR91_16105	COG2301	Belongs to the HpcH HpaI aldolase family
KKR91_16110	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KKR91_16115	COG3257	ureidoglycine aminohydrolase activity
KKR91_16150	COG1529	Aldehyde oxidase and xanthine dehydrogenase
KKR91_16155	COG0277	FAD linked oxidase domain protein
KKR91_16160	COG1620	l-lactate permease
KKR91_16165	COG1115	amino acid carrier protein
KKR91_16180	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KKR91_16185	COG0509	glycine decarboxylation via glycine cleavage system
KKR91_16190	COG0404	The glycine cleavage system catalyzes the degradation of glycine
KKR91_16195	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KKR91_16195	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KKR91_16200	COG1113	amino acid transport
KKR91_16205	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KKR91_16260	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KKR91_16270	COG0686	Belongs to the AlaDH PNT family
KKR91_16305	COG2197	response regulator
KKR91_16310	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KKR91_16320	COG0508	dehydrogenase complex catalyzes the overall conversion of
KKR91_16325	COG0022	dehydrogenase e1 component
KKR91_16335	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KKR91_16340	COG1950	PFAM Membrane protein of
KKR91_16355	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KKR91_16360	COG0820	rRNA (adenine-C2-)-methyltransferase activity
KKR91_16370	COG0590	tRNA wobble adenosine to inosine editing
KKR91_16380	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KKR91_16415	COG0667	Aldo Keto reductase
KKR91_16425	COG2409	Drug exporters of the RND superfamily
KKR91_16440	COG0277	FAD linked oxidase domain protein
KKR91_16450	COG1414	Transcriptional regulator
KKR91_16455	COG5002	protein histidine kinase activity
KKR91_16460	COG0596	Alpha beta hydrolase
KKR91_16485	COG2814	Major facilitator Superfamily
KKR91_16525	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KKR91_16525	COG2169	Transcriptional regulator
KKR91_16530	COG1595	DNA-templated transcription, initiation
KKR91_16540	COG0659	secondary active sulfate transmembrane transporter activity
KKR91_16545	COG0318	PFAM AMP-dependent synthetase and ligase
KKR91_16550	COG0697	spore germination
KKR91_16565	COG1191	sigma factor activity
KKR91_16580	COG0859	PFAM glycosyl transferase family 9
KKR91_16590	COG0438	transferase activity, transferring glycosyl groups
KKR91_16595	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
KKR91_16600	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
KKR91_16600	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
KKR91_16605	COG1028	Short-chain dehydrogenase reductase Sdr
KKR91_16620	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
KKR91_16620	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
KKR91_16640	COG0534	Mate efflux family protein
KKR91_16645	COG2814	Major facilitator Superfamily
KKR91_16670	COG0531	amino acid
KKR91_16680	COG0305	Participates in initiation and elongation during chromosome replication
KKR91_16685	COG0359	binds to the 23S rRNA
KKR91_16690	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KKR91_16700	COG0360	Binds together with S18 to 16S ribosomal RNA
KKR91_16705	COG1362	aminopeptidase activity
KKR91_16715	COG1131	(ABC) transporter
KKR91_16725	COG1131	(ABC) transporter
KKR91_16740	COG0738	Major facilitator superfamily
KKR91_16745	COG0488	(ABC) transporter
KKR91_16775	COG1260	myo-inositol-1-phosphate synthase
KKR91_16780	COG2759	Belongs to the formate--tetrahydrofolate ligase family
KKR91_16785	COG0438	transferase activity, transferring glycosyl groups
KKR91_16800	COG0406	alpha-ribazole phosphatase activity
KKR91_16805	COG0617	tRNA 3'-terminal CCA addition
KKR91_16825	COG0492	ferredoxin-NADP+ reductase activity
KKR91_16830	COG3118	belongs to the thioredoxin family
KKR91_16835	COG3409	Peptidoglycan-binding domain 1 protein
KKR91_16835	COG0860	N-Acetylmuramoyl-L-alanine amidase
KKR91_16845	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KKR91_16860	COG1215	transferase activity, transferring glycosyl groups
KKR91_16880	COG1192	Involved in chromosome partitioning
KKR91_16885	COG0357	Ribosomal RNA small subunit methyltransferase G
KKR91_16895	COG0706	membrane insertase activity
KKR91_16905	COG0594	ribonuclease P activity
KKR91_16910	COG0230	Belongs to the bacterial ribosomal protein bL34 family