locus-tag class description SEA_ALEDEL_26 COG0553 Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair SEA_ALEDEL_45 COG0749 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity SEA_ALEDEL_46 COG0104 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP