locus-tag class description SEA_HEADNERD_45 COG0258 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity SEA_HEADNERD_45 COG0749 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity SEA_HEADNERD_46 COG0104 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP