LOCUS MN617842 15549 bp DNA linear PHG 18-NOV-2019 DEFINITION Arthrobacter phage Saphira, complete genome. ACCESSION MN617842 VERSION MN617842.1 KEYWORDS . SOURCE Arthrobacter phage Saphira ORGANISM Arthrobacter phage Saphira Viruses; Caudovirales; Siphoviridae. REFERENCE 1 (bases 1 to 15549) AUTHORS Mastropaolo,M.D., Fallest-Strobl,P., Garlena,R.A., Russell,D.A., Pope,W.H., Jacobs-Sera,D. and Hatfull,G.F. TITLE Direct Submission JOURNAL Submitted (25-OCT-2019) Biological Sciences, University of Pittsburgh, 367 Crawford Hall, Pittsburgh, PA 15260, USA COMMENT Phage Isolation and DNA preparation performed at Baylor University, Waco, TX annotation analysis performed at Neumann University, Ashton, PA and sequencing by Illumina to approximately 1348x coverage was performed at Pittsburgh Bacteriophage Institute, University of Pittsburgh, Pittsburgh, PA. Assembled with Newbler and Consed as of Jan 2016. Supported by the Howard Hughes Medical Institute Science Education Alliance. ##Assembly-Data-START## Assembly Method :: Newbler and Consed v. Jan-2016 Coverage :: 1348x Sequencing Technology :: Illumina ##Assembly-Data-END## FEATURES Location/Qualifiers source 1..15549 /organism="Arthrobacter phage Saphira" /mol_type="genomic DNA" /isolation_source="soil" /db_xref="taxon:2664221" /lab_host="Arthrobacter sp. ATCC 21022" /country="USA: Waco, TX" /lat_lon="31.547985 N 97.120277 W" /collection_date="01-Oct-2015" /collected_by="S. Heady" /identified_by="S. Heady" gene 43..348 /gene="1" /locus_tag="SEA_SAPHIRA_1" CDS 43..348 /gene="1" /locus_tag="SEA_SAPHIRA_1" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="QGH75222.1" /translation="MTEYAPMLPGFEAPKTGMSKLEQRCSQHLVMLQNLGLLKDQDQV MAQLVMDLAHAVALSSAAGKAAGTALAVKPLMEALDKLPKPATEDAFAAMMKEAGLV" gene 345..560 /gene="2" /locus_tag="SEA_SAPHIRA_2" CDS 345..560 /gene="2" /locus_tag="SEA_SAPHIRA_2" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="QGH75223.1" /translation="MTTNPAELTFDMNFHAFVLAVPLRTTEAGMMLGQPVIAMNQGGE DQLVMALRAIADDIEARGIDVVGKWRL" gene 648..806 /gene="3" /locus_tag="SEA_SAPHIRA_3" CDS 648..806 /gene="3" /locus_tag="SEA_SAPHIRA_3" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="QGH75224.1" /translation="MAGDFRDHRVDGWPMQMMSMPLDWYFDMNERAGIEFPVNGDETA QRKDGQLW" gene 800..2290 /gene="4" /locus_tag="SEA_SAPHIRA_4" CDS 800..2290 /gene="4" /locus_tag="SEA_SAPHIRA_4" /codon_start=1 /transl_table=11 /product="terminase" /protein_id="QGH75225.1" /translation="MVTAIADELPELLAALESSTAEYATKPTPGAPNELGQILGTAKL LGRQLMPWQIEVSRVASEKRIDDPRRYRYPIVVLTVPRQSGKTTLMRTVLAQRALKCR NRKAFYTAQTGKDATARWLDLVKDIEDGALSQFVSKRIAAGSQALTFPTGSTISPFAP TAKSLHGYTPHDVMLDEIFAHDEAAGNDLMGAIRPAQLTLVDKQLWLVSTAGTADSKF LKSWVDQGRLAVKDSGAGIAYFEWSLPEGLDPYDPQNWLFHPAVGHTITLQDLADDAE SQSPGEWLRAYMNRWTSTSEAVIDVAKWDTLAGPLVPVPWAQVSIAYEVAHDRSCAAI YACWTDPESGKPALKLVQQGSGAEWLAPAVAKIYVENRPKAIGADDGGPTKAVTDALR RMPNARSGGNGVEVTTLTARDFATACVSYMGHIDDGTILHDGDPGHRAAVESAATRPM GDSKVFSRRHSRGPIPELVAATVALRLHEQAPVTAPKPAIYMGRGN" gene 2294..2497 /gene="5" /locus_tag="SEA_SAPHIRA_5" CDS 2294..2497 /gene="5" /locus_tag="SEA_SAPHIRA_5" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="QGH75226.1" /translation="MIRLDKTQFSIVVVCTLCPFWRSLHNDKDLALAAGRRHNTTAHA GDNSTLSAARQQAYRARKAAAGG" gene 2549..3709 /gene="6" /locus_tag="SEA_SAPHIRA_6" CDS 2549..3709 /gene="6" /locus_tag="SEA_SAPHIRA_6" /codon_start=1 /transl_table=11 /product="portal protein" /protein_id="QGH75227.1" /translation="MPLWNKPLAKPAGILARQAAASVDVLAGNVVTWEYAEPNPAPRE HFETLTLAHLLGMEYVNIDRAAAMGIGAVAKLRKTACGFIGRMPLIAYRGHDVLTRQP KIVVQPEAGRPRFVTMAWVTEALMFYGRAWFTVEERYAEDNRPSRFKWVPEWKAEFNT AGQLVKAYGVEVDPADVVRVDGIDEGLLNYAQPVLREARAIDIAAGRASDNPVPSIDL HQTGGDPLTNDEIDALIDRWATNRRAKNGGVSFTNQSVEAKTMGQPVEQLLIDGRNVA ALNIARAAGFPAWAVDASVNGSSITYSNSPSRTRELIDYALSPYLEAIAARFSMDDIL PAGTWCRFDYSELLRGDFAARMDAYKVAKEAEIYSVEELRAMELGRPLEVTE" gene 3706..5289 /gene="7" /locus_tag="SEA_SAPHIRA_7" CDS 3706..5289 /gene="7" /locus_tag="SEA_SAPHIRA_7" /codon_start=1 /transl_table=11 /product="major capsid and protease fusion protein" /protein_id="QGH75228.1" /translation="MKHAYLNLSAGLLTASASTRTISGEIVEYGVVGHTSLGPTIFQA GSITAPTPLSKVKMLISHDSERSVGFLDSLEDNGNKPFAAFKVPAGDEGDEALTKAAN GTRDSFSVGVHVQEYSFDDEGNLLVHASTLKEVSLVTIPAFENALVHDVAANRKEATM TVEEMRAQALANAQTPGNPAVALAAAAADNAPSPAESAPSTQPATVPTRHATAAEAQA APIQVGGRRGLDISAAANIVIDHLRAGLPATQLSAALSDVVPADDAGEGFLRPTFIGE LWQAFNDDRPLIDAFGTPGKLTGTKVYGWKWDLANRPKVGRYAGNKTEVPSNPLKTVP AESDAQDFAAGWDVARKYIDLGAADFIESVFRGATADYRLQTEIWFGEQILAEATEVA GVTTVLGALSQFNVEAARIGAKLSTIQFGVDAWEEFINLPESQVPWWLKAQGTVELDG MKGRAGGVSFSANLGLGAGQILGADKRAATYYEAGSVPIRVTAQDIPRGGVDLGVFGY AGAIVHDPRAIWVSDDGLV" gene 5293..5649 /gene="8" /locus_tag="SEA_SAPHIRA_8" CDS 5293..5649 /gene="8" /locus_tag="SEA_SAPHIRA_8" /codon_start=1 /transl_table=11 /product="head-to-tail adaptor" /protein_id="QGH75229.1" /translation="MIVTTEQVRTWLGLPASDPALEDATAATNAFVERLGLPMQPKFV DGIAVLDDDGALMYEPAADTVLGAKMLAARLYRRRNSPSGVEAITDAGTSFVARYDSD ISRYLKLDGFAAPRIG" gene 5652..6008 /gene="9" /locus_tag="SEA_SAPHIRA_9" CDS 5652..6008 /gene="9" /locus_tag="SEA_SAPHIRA_9" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="QGH75230.1" /translation="MRTMGNALKDIAEMVTAAGVPAAVDPRDLNLPGAWVTPGLVSFE VLDVDTAFMTFDIYLVAPDHGAVHSLNSLGDMLAKIRPALQVGEAMPVMVNLPNHGAD ALPALLISINAQITED" gene 6014..6436 /gene="10" /locus_tag="SEA_SAPHIRA_10" CDS 6014..6436 /gene="10" /locus_tag="SEA_SAPHIRA_10" /codon_start=1 /transl_table=11 /product="major tail protein" /protein_id="QGH75231.1" /translation="MATDVITVGPGRFTIGSDTELTVFSGQVTSLRLVPSVDVGDSIY VLDGGEVSGDRTESWNVSGTMLQDFGATTSKTEWLFEHRGEDMPFAYAPNSARGKEIT GTLTVEAIEIGGDVKTKPTSDFEFKLVGPPAIGTVSAG" gene 6436..6813 /gene="11" /locus_tag="SEA_SAPHIRA_11" CDS 6436..6813 /gene="11" /locus_tag="SEA_SAPHIRA_11" /codon_start=1 /transl_table=11 /product="minor tail protein" /protein_id="QGH75232.1" /translation="MAAKLYAVVGGAKLRSTLRKAGADMKELSAVNRDVANIVLPVAR ATAPSVSGKLGSTVRAGATQKSAIIRVGSAKAPYGPVVHFWHKGNFTPQPWVSLAAQK TEPTWLARYHAGIEKIINQVTGA" gene 6819..7169 /gene="12" /locus_tag="SEA_SAPHIRA_12" CDS 6819..7169 /gene="12" /locus_tag="SEA_SAPHIRA_12" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="QGH75233.1" /translation="MAQLSAPKVIVMLEASGTDELTEYTVQTDNRDAIQWDVTRPRRS WPAFNEAPMLYMTFLAWHAMHRTGATKLSLDEFMKDAVEVKVLSAAGKAIDPTEAIAE DVLVDPTQPAAATA" gene 7166..7273 /gene="13" /locus_tag="SEA_SAPHIRA_13" CDS 7166..7273 /gene="13" /locus_tag="SEA_SAPHIRA_13" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="QGH75248.1" /translation="MIVELALATNIAPSVWAAESTEVIATALTILEERK" gene 7280..9277 /gene="14" /locus_tag="SEA_SAPHIRA_14" CDS 7280..9277 /gene="14" /locus_tag="SEA_SAPHIRA_14" /codon_start=1 /transl_table=11 /product="tape measure protein" /protein_id="QGH75234.1" /translation="MYRTAVLAVRIVTETKEADKGIDETVGKFEKFERGLDKATLPAA AAGAAVLGFAKKTGDMASIAQQNAGAVDSVFKGNAKTVNEFAATAADKLGLSGSAYQQ MASVIGSQLKNMGVPMDQVAGSTNDLISKGADLAAMFGGTTSDAVDALSSLLRGERDP IEKYGVSINDAAIQAKKAELGLAGLSGEADKNATLTATMAILQKQTADATGQFAREAD SAAGAQERANAKIQDAGAKLGSVFLPAMAAAASAAGGMATWASENSTVLLVLAGVIGG VAGAILLVNGALKAWRAATAAVAAVQVVLNAVMSANPIGLVVLAIAALVAGLVWAYNN VGWFKDFVDQAFAAIGAVVAAVAQWFQDAWNNAVTFVQAYIEAWSIIINAVFTGIQTA VGAVAQFFTDAWNNAVTFVQAYIAAWGIIINAVFNGVQSAVGAVADFFRTAWAVAVAI VAGVIRSWQAGVNAVFNAVGSFISGVVNNVRNVFSSVFNVILGIVTGVIGGVRGVIDG VSSTVQNVASIINGALVAAFNFVASAGRNAFAGITGAIQGVIGWIQNALSWVRNLASG IGNAVGQMLGLGGATAATEDAPGLSYFGGGNPGFEGGATSIFGGNSFFGAPAAKAAAP IIVNLTVNGALDPTAVGKQIYDILLKYLRRNGDVVNGATPW" gene 9271..11088 /gene="15" /locus_tag="SEA_SAPHIRA_15" CDS 9271..11088 /gene="15" /locus_tag="SEA_SAPHIRA_15" /codon_start=1 /transl_table=11 /product="minor tail protein" /protein_id="QGH75235.1" /translation="MVTIQEAALTIAGGTYNPGKPAAFILPTAFSGLTVSYGGDSCAD HPGPGSISGRVFIPEQHAAFHPRIADPVHLRATINGDDMRMFYGTVDEIVIEDVDGEP LPAIIPNSRGMQNLAGWTITTGTTYAGAAPVPATFLLDGARVSALGPTQGGTAGKLWF TTPAAPVLETRPYVVTAMAESPTGLPALKAQWLNGAGVVIKTEDLYRWYTAGSFNGDF SPLRTNGTYPPVGAKTVRIIVECDLYPDRESWQQSCGVDGIVLHELPYGTWDIPALKP DKRPPGRWVTFKASDILATAARLIVGTTPWPSQTVEGRTAALNALVPAGAVTFNEGGT RDPFRLLGPRDIDKQNMLEIFQRVLASSGDLAVASSNFARYVVAASLPRYPQIIDRVN GVATIVKDPLVPELPAGSIVAGPMQTDITTMANQIRVEYRVVTDTMEQTGDDASAVYV NAESLTAYGAMGRSISTDLATVAGSRAEDKARRLAESQAQPFYRLADKVRLVSSQIPD APNVARLYSADIGFGQLIYVPDAPAVLGNYHRVRGATLTLGREPAVELDVEPPDYSAP EALTFGEARNTTPPFNILKLSEFQNITIGQLKYVSALEE" gene 11094..11612 /gene="16" /locus_tag="SEA_SAPHIRA_16" CDS 11094..11612 /gene="16" /locus_tag="SEA_SAPHIRA_16" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="QGH75236.1" /translation="MDLSGAFPKLTDADSVYAIKEYSERMFTELDKMPRGLIGRSNLN GSTAGIGAASVMVDLVAVPLVAGRWYKVEYVLTTVAGGPNDAIAYDFKKSAVNDSSAA GTSLNDGTQRYIYTGPAAGNSKTEVIRTVFKAPSNETQVIKAILARATGSVAFTANSR GLYVFDMGTTAL" gene 11609..12058 /gene="17" /locus_tag="SEA_SAPHIRA_17" CDS 11609..12058 /gene="17" /locus_tag="SEA_SAPHIRA_17" /codon_start=1 /transl_table=11 /product="lysin A, protease domain" /protein_id="QGH75237.1" /translation="MTTMTLAYPLVEGETIQEFGARQSFYRKLGQLGHNGIDLGCEVG TPVYAMAAGTVLHAGWSHDHPWLTHHAGIAVLTHHGEHISGLAHLSKVVVSPGDRVEV GQLVGYSGDTGTAGVPHVHCELLAAQPDWSNGYAGRIRFEFSKGELN" gene 12055..12699 /gene="18" /locus_tag="SEA_SAPHIRA_18" CDS 12055..12699 /gene="18" /locus_tag="SEA_SAPHIRA_18" /codon_start=1 /transl_table=11 /product="lysin A, N-acetylmuramoyl-L-alanine amidase domain" /protein_id="QGH75238.1" /translation="MTYQYLTGQTSPFQSPRTQPIQSITIHWWDKPERNPTFQGTVDW LCRIGTTASIHYVAEAGRVACLVAPDRIAWHAGDGGLGVGNNTSIGIECNPRQSDGDY QTVAELVRDLRAVYGNLPIYPHRHWTNTECPGTYDLARINRLAATPAPSQEDEMNPEQ NRMLVALYNAFFNKKSLPTPDNQSIVGGEAIDDLININDNKILAELREIKNKLS" gene 12696..12905 /gene="19" /locus_tag="SEA_SAPHIRA_19" CDS 12696..12905 /gene="19" /locus_tag="SEA_SAPHIRA_19" /codon_start=1 /transl_table=11 /product="holin" /protein_id="QGH75239.1" /translation="MSAKPTPKVAAVGVSGALTVLIVWVAGLCGIDMPAEVAAAISVV VTFGAGYIKSEVTERDGSGGEHVAR" gene 12874..13152 /gene="20" /locus_tag="SEA_SAPHIRA_20" CDS 12874..13152 /gene="20" /locus_tag="SEA_SAPHIRA_20" /codon_start=1 /transl_table=11 /product="membrane protein" /protein_id="QGH75240.1" /translation="MDQEVSTLPDSGTWTQPEVVRSLQRIERKLDNAVTSSYVEALKA DQLRKDNEQDKAIEAVEQNHNKLLLLVVSTALGSAASLIVALASALPK" gene 13220..13474 /gene="21" /locus_tag="SEA_SAPHIRA_21" CDS 13220..13474 /gene="21" /locus_tag="SEA_SAPHIRA_21" /codon_start=1 /transl_table=11 /product="helix-turn-helix DNA binding domain protein" /protein_id="QGH75241.1" /translation="MASKAKCETTEYAGMLRRMIRAYGRRVGDADVEDLAVMLEVQRE LDAAIQAAVDSQRENHGRSWADIARATGTSRQAAQKKYGV" gene complement(13503..13775) /gene="22" /locus_tag="SEA_SAPHIRA_22" CDS complement(13503..13775) /gene="22" /locus_tag="SEA_SAPHIRA_22" /codon_start=1 /transl_table=11 /product="helix-turn-helix DNA binding domain protein" /protein_id="QGH75242.1" /translation="MTTRVQARPASTDADIGKRIERRLSALGMTQWDLAARLGLTQAT VSRKLHGQRPWFASELVTVAGVLGCAVGELFGERCRPAVRPNVARI" gene 13885..14118 /gene="23" /locus_tag="SEA_SAPHIRA_23" CDS 13885..14118 /gene="23" /locus_tag="SEA_SAPHIRA_23" /codon_start=1 /transl_table=11 /product="MerR-like helix-turn-helix DNA binding domain protein" /protein_id="QGH75243.1" /translation="MPEGYSVQGMTEHSSETTELVEAAQAAVLLGVSKRTLDRYQAAG LITPIRPIQGKGAIRRFDAQDVQRLAVAQDGQP" gene 14115..14783 /gene="24" /locus_tag="SEA_SAPHIRA_24" CDS 14115..14783 /gene="24" /locus_tag="SEA_SAPHIRA_24" /codon_start=1 /transl_table=11 /product="helix-turn-helix DNA binding domain protein" /protein_id="QGH75244.1" /translation="MSIESMAVVLHHSQAGGTDKLVLLGIANHDGDGGSWPSIATLAR YANVEPRAVKACINRLVARGEVERERQAGGTRNMPDYSRPNLYHLKVVCPPECDRSAQ HRINRKDPVSSTTPGVVTIPPGGYVPDTPGGVRPTTPKPSTNHPYNSDKSPSSSTSPA ENGKLPCWNCGEHVIANTTKPKRYCQPCSSRGLDNPLIPCKKCGSVRKRAFPGEQEFD CGCV" gene 14770..14985 /gene="25" /locus_tag="SEA_SAPHIRA_25" CDS 14770..14985 /gene="25" /locus_tag="SEA_SAPHIRA_25" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="QGH75245.1" /translation="MDAFEPYETYSMAVLWNMGIRNAHDVPLDGDAMARRLAAERAVQ IHWQTVSPAQVQALKDNHHQVDKDSRS" gene 14982..15269 /gene="26" /locus_tag="SEA_SAPHIRA_26" CDS 14982..15269 /gene="26" /locus_tag="SEA_SAPHIRA_26" /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="QGH75246.1" /translation="MISTESVEIARKTSLDAQHVAELFQDAIDQARETYVNDSKTDTW SEYIHALSQYQAAARRATAARLMADAVAHAYHLEQAWERCKALPITINAAR" gene 15256..15522 /gene="27" /locus_tag="SEA_SAPHIRA_27" CDS 15256..15522 /gene="27" /locus_tag="SEA_SAPHIRA_27" /codon_start=1 /transl_table=11 /product="HNH endonuclease" /protein_id="QGH75247.1" /translation="MLPGDWGGREAQRLTELCMATYGWTCHLCKQPIRQGEQSADHLL PRKWGGSNDLSNLRPAHRKCNYARGAKLLSDPRARPTDNTAFFN" ORIGIN 1 ccgtcttttt ttccccgact caaaacaaaa ggaggaccga ccatgaccga atatgccccg 61 atgctgcccg ggtttgaagc tcccaagacc ggcatgagca agcttgaaca gcgttgctct 121 cagcaccttg tgatgctcca aaatcttggc ttgctcaagg accaagatca agtcatggct 181 cagctcgtga tggatcttgc ccacgccgtg gcgctcagct cagccgccgg caaggcagcc 241 ggcacagcat tagccgtcaa gccgcttatg gaagcacttg acaagctacc caaaccagca 301 accgaagatg cgtttgccgc aatgatgaaa gaggccggcc tagtatgacc accaatccag 361 cagaactgac gttcgatatg aattttcacg cttttgtctt ggctgtcccg ttgcggacca 421 ccgaggccgg catgatgctt ggtcagccgg tgatagcaat gaaccaaggc ggcgaggatc 481 agcttgtcat ggcgctacgt gcgatagccg acgacattga ggcccggggc attgacgtag 541 ttggaaagtg gcggctgtga gcgcggttga cgcggcaacg gtggccgtgc ttgtaagtta 601 tggctcgctt gtgctggcaa cggccggcgt gcttgtggcg gcgatccgtg gccggtgact 661 tccgggacca ccgcgtagac ggttggccta tgcagatgat gagcatgccc ctcgattggt 721 atttcgatat gaacgagcga gccggcattg agttcccggt gaacggcgac gagacggcgc 781 aacgaaagga cgggcaactg tggtaacggc aattgcggac gagctgcccg agctgctggc 841 agccttggag agttccacgg ccgagtatgc gaccaagcca acccccggcg ctcccaacga 901 gctgggacag atccttggca ccgccaagct acttggccgg cagctcatgc cgtggcagat 961 cgaagtctcc cgcgtggcat cggaaaagcg catagatgat ccgcgccggt accgttaccc 1021 gattgtggtt ctgacggtgc cccggcagtc aggcaagaca acgctcatgc ggacggtctt 1081 ggctcaacgt gctttgaagt gccgcaaccg taaggcgttc tacaccgccc aaacgggcaa 1141 agacgctacg gcgcgttggt tggatcttgt caaggacatt gaggacggcg cactgtccca 1201 attcgtgagc aagcgcattg cggccggcag ccaagcgctg acgttcccga cgggcagcac 1261 catcagcccg tttgccccga cagccaagag cttgcacgga tatacccctc atgacgtgat 1321 gttggatgaa atctttgccc atgacgaagc ggccggcaat gaccttatgg gagctatccg 1381 gccggcacag ttgacccttg tggacaagca actgtggctt gtcagcacgg ccggcacggc 1441 tgacagcaag ttcctcaagt catgggtgga tcaaggccgg cttgccgtca aggacagcgg 1501 tgccggcatt gcctactttg agtggagctt gcccgagggc ttggacccgt atgaccctca 1561 gaactggcta ttccacccgg ccgtggggca caccatcacc ttgcaggatc ttgccgacga 1621 tgccgagtca cagagtccag gcgaatggct ccgcgcctat atgaaccgtt ggacgagtac 1681 gagcgaggca gtcattgacg tagccaagtg ggacacgttg gccggcccgt tggtacccgt 1741 tccatgggca caagtgagca ttgcctacga agtggcgcac gacaggagtt gcgcggcgat 1801 ctatgcgtgt tggacagatc ccgagagcgg caagccggcg ctcaagctcg tgcaacaggg 1861 cagcggtgcc gagtggcttg ccccggctgt tgccaagatc tacgtggaga atcggcccaa 1921 ggcaatcggg gccgacgatg gtggaccaac caaggcagtg accgacgcgt tgcggcgcat 1981 gcccaatgcc cgtagtggcg gcaacggcgt cgaggtcact accctgacag cccgggactt 2041 tgctaccgct tgcgtgtcct acatggggca cattgacgac ggcacaatct tgcacgacgg 2101 cgacccgggg caccgtgccg ccgtcgagtc agcggcaacc cgtcccatgg gagacagcaa 2161 ggtctttagc cggcgtcaca gccggggacc aatccccgag ttggtagcgg caaccgtagc 2221 gctacgactt cacgagcaag caccagtcac ggcaccgaag ccggctatct acatgggacg 2281 aggaaactag ggaatgatcc ggcttgacaa gacacaattc agcattgttg ttgtatgcac 2341 cttgtgcccg ttttggcgct cgttgcataa cgataaggat cttgccctag ctgccggccg 2401 gcgtcacaac accacggcgc acgccggcga caacagcacc ttgtcagcgg cgcggcagca 2461 agcctacagg gcacgcaaag ccgctgccgg gggataatcc catccatgta attttgagtc 2521 cgttacgggg gcatacagaa tcttctgtat gcccctctgg aataaaccac tagccaagcc 2581 ggccggcatc cttgcccgtc aggcagccgc cagcgtcgat gttcttgccg gcaacgtagt 2641 cacgtgggag tatgccgaac ccaacccggc accgcgtgag cactttgaaa ctctgactct 2701 tgcacatttg cttggtatgg agtacgtcaa cattgaccgt gcagccgcta tgggcatcgg 2761 tgccgtagcc aagctgagaa aaaccgcttg cggctttatc ggccgcatgc cccttatcgc 2821 ttaccgtggg cacgacgtgc tgacccgtca gcccaagatt gtggtacagc ccgaggccgg 2881 ccggccccgc tttgtcacga tggcatgggt gaccgaagct ctcatgttct acggccgcgc 2941 ttggttcacc gtcgaagaac gctacgccga ggacaatcgg ccgtcgcgtt tcaagtgggt 3001 gcccgagtgg aaagcagagt tcaacaccgc cggccagctc gtgaaagcct acggcgtcga 3061 ggttgacccc gctgacgtgg tgcgcgtgga cggcattgac gagggcttgc ttaactacgc 3121 tcagcccgtc ctacgtgagg cccgggcaat cgacattgct gccggccgtg catcggataa 3181 ccccgtaccg agcattgact tgcaccagac cggcggcgac ccgctgacca atgacgagat 3241 tgacgctctc attgaccgtt gggcaaccaa ccgacgcgcc aaaaacggcg gcgtgagctt 3301 caccaaccaa agcgttgaag ccaagaccat ggggcagccc gtcgagcaac tgctgatcga 3361 cggccggaac gtggcagcct tgaacattgc ccgggcagcc ggtttcccgg cgtgggcagt 3421 cgatgccagc gtcaacggca gctccatcac ctacagcaac agcccgagtc gcacgcgtga 3481 gctgattgat tacgcgctgt cgccgtatct ggaagctatc gccgctcgtt tcagcatgga 3541 tgacattttg ccggccggca cgtggtgcag gttcgactat tccgagctgt tgcgcggcga 3601 cttcgctgcc cgtatggacg cttacaaagt cgccaaagaa gcagaaatct attcagttga 3661 ggagctacgc gccatggagc ttggccggcc gttggaggtc acagaatgaa gcacgcatat 3721 ttgaatctgt ccgccgggtt gctgacggca agcgcgtcaa cccgaaccat tagcggcgag 3781 atcgtcgagt acggagttgt ggggcacacc agtcttggcc cgacgatctt ccaagccggc 3841 agcatcaccg cccctactcc gctgtccaaa gtcaaaatgc tgatcagcca cgactcagag 3901 cgcagtgtgg gtttcttgga ctcgttggag gacaacggaa ataagccgtt cgccgcgttc 3961 aaggttcctg ccggcgacga gggcgacgag gcattgacca aggcagccaa cggcacccgg 4021 gactcgttca gcgtcggcgt gcacgtgcag gaatacagct ttgacgacga gggcaacttg 4081 cttgttcacg cgtcaacgct caaggaagtt tccctagtaa caatcccggc attcgaaaac 4141 gcgctcgttc atgacgtagc ggcaaacagg aaagaggcaa caatgaccgt cgaagaaatg 4201 cgcgctcagg ctttggccaa cgcacagacc cccggcaacc cggccgtagc tctcgctgct 4261 gctgctgccg acaatgcccc gtcgccggcc gagtccgccc ccagcactca gccggcgacg 4321 gttccaaccc ggcacgctac cgctgccgaa gcccaggcgg ccccgattca ggttggcggc 4381 cggcgcggtc tggacatttc cgcggctgcc aacatcgtca ttgaccacct ccgggcagga 4441 ctgccggcaa cacagctcag cgcggcactg tccgacgtgg taccggccga tgatgccggc 4501 gagggtttcc tccggcctac gttcatcggt gagctgtggc aagcgttcaa cgatgaccgg 4561 cccctgattg acgctttcgg caccccgggc aagctgaccg gtaccaaggt gtacggctgg 4621 aagtgggatc ttgccaaccg ccccaaggtc ggccgctacg ccggcaacaa gaccgaggtt 4681 ccatctaacc cgctcaagac cgtgccggcc gagtccgatg cacaggactt tgccgccggc 4741 tgggacgtgg cacgcaagta cattgacctt ggtgccgctg actttatcga atcggtgttc 4801 cgtggtgcga ccgctgatta ccgtttgcag accgaaattt ggttcggtga gcagatcctt 4861 gccgaagcaa ccgaagtcgc cggcgttacc acggtgttgg gcgcactgtc tcagttcaac 4921 gtggaggctg cccgtatcgg tgccaagctg tcaacaattc agttcggcgt ggacgcgtgg 4981 gaggaattta tcaacctgcc cgagtctcag gttccttggt ggctcaaggc tcagggcacc 5041 gtagagcttg acggcatgaa aggacgcgcc ggcggtgttt cgttcagcgc gaaccttggt 5101 cttggtgccg gccagatcct tggagccgac aagcgtgccg cgacgtacta cgaagccggc 5161 agcgtgccga tccgtgtaac cgctcaggac atcccccggg gcggcgtaga ccttggtgtc 5221 tttggctacg ccggcgctat cgttcatgac ccccgcgcca tttgggtctc agacgacgga 5281 cttgtataac ccatgatcgt cacgacagaa caggttagga cgtggctagg gctgccggca 5341 tcggacccgg ccctagaaga tgccacggcc gcaaccaacg ctttcgttga acggcttggg 5401 ctgccgatgc aacccaagtt cgtggacggc attgccgtac tggacgacga cggggcactc 5461 atgtatgagc cggcggcaga cacggttcta ggtgccaaga tgctggcagc aaggctctac 5521 cgccggcgca acagccctag cggcgtcgaa gcgatcaccg atgccggcac gtcgtttgtt 5581 gcccggtatg acagcgacat tagccgttac ttgaagctgg acggctttgc ggccccgagg 5641 attggctgat catgcggacc atgggtaacg cactcaagga catcgcggaa atggtgacag 5701 cggccggcgt gccggctgct gttgaccccc gtgacctcaa cttgcccggg gcatgggtga 5761 cccccggtct tgtcagcttt gaggtgctgg acgtggacac agcctttatg acgtttgaca 5821 tttatctagt tgcccctgac cacggtgccg tacattcgct caacagtctt ggggacatgt 5881 tggcgaagat ccggccggcc ctacaggttg gtgaggctat gccagtgatg gtgaacctcc 5941 ctaaccatgg tgccgacgcg ttgccggcgc tacttatcag catcaacgca caaataacgg 6001 aggactaacc accatggcta ctgacgtaat taccgttggc cccggccgct ttaccatcgg 6061 ttccgataca gagctgaccg tcttttccgg tcaggtaacc agcttgcgac tcgtgccgag 6121 cgtggacgtt ggcgactcaa tctatgtgct ggacggcggc gaagtgtccg gcgaccgtac 6181 cgagtcgtgg aacgtgtccg gcacgatgtt gcaggacttt ggtgcgacca ccagcaagac 6241 cgaatggctg ttcgaacacc ggggcgaaga tatgccgttt gcctacgctc caaacagtgc 6301 caggggtaag gagattaccg gcacgctgac cgtcgaggcc attgagattg gcggcgacgt 6361 caagaccaag cccacgtctg actttgagtt caagctggtt ggacctcccg caattggcac 6421 cgtttccgcc ggctaatggc agcgaaactc tacgccgtgg ttggcggcgc gaagctcaga 6481 agcacgctga gaaaagccgg cgcagatatg aaagaacttt ctgccgtcaa ccgcgacgta 6541 gccaacatcg ttttgccagt cgccagagca acagcgccaa gcgtcagcgg caagcttggc 6601 agcaccgtta gagccggagc aacccagaag tcagcaatca tccgtgtggg cagcgcgaaa 6661 gcaccctacg ggccggtggt gcacttctgg cacaagggga acttcacccc acagccttgg 6721 gtgtcgctgg cagcccaaaa gacagagcca acatggctag cccggtatca cgccggcatt 6781 gagaaaatca tcaaccaagt cacaggagca taagaaccat ggcgcagcta tccgccccga 6841 aagtaattgt catgctggaa gcatccggca ccgacgagct gaccgagtac accgtgcaga 6901 ccgataaccg cgacgcgatc cagtgggacg taacccggcc ccgtcgctcg tggccggcat 6961 tcaacgaagc acccatgctg tacatgacgt tccttgcatg gcatgcaatg caccgtaccg 7021 gggcaacgaa actctcgctt gacgagttca tgaaagacgc cgtggaagtc aaggtactgt 7081 cagcggccgg caaagcaatt gatcctaccg aagccattgc cgaggacgta ctcgtggacc 7141 ctacccagcc ggcagccgct accgcttgat agtcgagctt gcgcttgcga ccaacattgc 7201 gccaagcgta tgggctgccg agtccaccga agtaatagca acagccctga ccattttgga 7261 agaacgaaag taggccacaa tgtaccggac agccgtcttg gccgttcgta tcgtcacgga 7321 gacaaaagag gccgacaagg gcattgacga aacagttggg aagttcgaga agttcgagcg 7381 aggactagac aaggcaacat tgccggcggc tgccgccggc gctgctgtcc ttggtttcgc 7441 caagaaaacc ggcgatatgg cgagcattgc ccagcagaac gccggcgctg ttgacagcgt 7501 gttcaagggc aatgccaaga ccgtcaacga gtttgccgcg acggctgctg acaagcttgg 7561 gctgtccggt agcgcgtatc agcaaatggc gtcggtgatt ggttcccagc tcaagaacat 7621 gggcgtgccc atggatcagg tagcgggatc taccaatgac ctgatcagca aaggtgccga 7681 cttggcggca atgttcggcg gcacgacttc cgatgccgtg gacgcgctat ctagcttgct 7741 acgtggtgag cgtgacccca ttgagaagta cggcgtcagc atcaacgatg ccgcgatcca 7801 agccaagaaa gcagagcttg gccttgcagg gttgtccggt gaggctgaca agaatgcgac 7861 cctgacggca accatggcga tcttgcagaa gcagacagcc gacgcaacag ggcagttcgc 7921 acgcgaggcg gacagcgcgg ccggcgctca ggaacgagct aacgcgaaga tccaagacgc 7981 cggcgcgaag cttggcagcg tgtttctgcc ggcaatggct gcggcagcat cggcagccgg 8041 cggcatggct acgtgggcat cggaaaacag caccgtcttg ctcgtgcttg ccggcgtcat 8101 tggcggcgtg gccggcgcga tcttgcttgt caacggggca ctcaaggcgt ggcgtgctgc 8161 cacggccgct gttgccgccg tgcaggtggt actcaacgcc gtaatgtctg ccaacccgat 8221 tggcctagta gtccttgcca ttgccgctct cgtggccggc ctagtgtggg cttacaacaa 8281 tgtgggttgg ttcaaggact ttgttgacca agcctttgcc gctatcggtg ccgtggtggc 8341 tgccgtggcc cagtggttcc aagacgcgtg gaacaacgcc gtcacctttg tacaggcgta 8401 catcgaagct tggtccatca tcatcaacgc cgtgttcacc gggatacaaa cggccgttgg 8461 tgccgtggcc cagttcttca ccgacgcgtg gaacaacgcc gtcacctttg tacaggcgta 8521 cattgccgct tggggcatca tcatcaacgc cgtgttcaac ggggtacagt ccgcagtcgg 8581 tgccgtggct gactttttcc gaaccgcgtg ggctgttgcc gtggcaatcg tggccggcgt 8641 gatccggtca tggcaagccg gcgtcaacgc tgttttcaac gccgtgggat ctttcatttc 8701 cggcgtagtg aacaatgtcc gaaacgtctt ttcatcggtg ttcaacgtga tccttggtat 8761 cgtcaccggc gtcataggcg gcgtgcgagg cgtgatagat ggtgtttcca gcaccgtgca 8821 gaacgtcgcc agcatcatca acggggcact cgtggccgcg ttcaactttg ttgccagcgc 8881 cggccgcaac gcttttgccg gcatcaccgg ggcaatccaa ggcgtcattg ggtggatcca 8941 aaatgcgttg agctgggtaa ggaatcttgc aagcggcatc ggcaacgccg taggccagat 9001 gcttggcctt ggtggggcaa cggcagcgac ggaggatgcg cctggactca gctactttgg 9061 cggtggcaac cccggttttg agggcggcgc cacaagcatc tttggcggca acagtttctt 9121 tggtgccccg gcagccaagg cagcggcccc catcatcgtc aacctgaccg tcaacggggc 9181 actggacccc acggccgtag gcaagcagat ctacgacatt ctgctgaagt acttgcgccg 9241 taacggtgat gttgtgaatg gagctacccc atggtgacaa tccaagaggc agcgctgacc 9301 attgccggcg gaacgtacaa cccgggcaag ccggccgcgt tcatcctgcc gacagccttt 9361 agcgggttga cggtgagcta cggcggcgac tcgtgcgccg atcaccccgg ccccggcagc 9421 atcagcggcc gtgtgttcat ccccgaacag catgccgctt ttcatccccg tatcgcggac 9481 ccggtacatt tgcgtgccac catcaacggc gacgatatgc gcatgtttta cggcactgtg 9541 gacgagattg tcattgagga cgtggacggc gagcccttgc cggctatcat ccccaacagc 9601 cggggcatgc agaaccttgc cggctggaca atcaccacag ggaccaccta cgccggcgct 9661 gccccggtgc cagcaacttt tctgctggac ggtgcacgcg tgtctgcctt gggaccaacc 9721 caaggcggca cggccggcaa gctgtggttc actacgccgg ccgcgccggt gttggaaaca 9781 cggccctacg tggtgactgc catggccgaa tcaccgacag gtttgccggc gctcaaggcg 9841 cagtggttga acggtgccgg cgttgtgatc aagaccgagg atctttaccg gtggtacacc 9901 gccggcagtt tcaacggcga cttttcaccg ctcaggacca acggcaccta tccgccggtt 9961 ggagccaaaa cggtcaggat cattgtggag tgcgatcttt acccggacag ggagagctgg 10021 caacagtcct gcggcgtgga cggtattgtc ctccatgagc tgccctacgg cacatgggat 10081 attccggcgc tcaaaccgga caagcggccc ccgggacgtt gggtgacgtt caaggcatcg 10141 gacattctgg cgaccgctgc ccgtctcatc gtggggacaa cgccgtggcc gtcacagacc 10201 gttgagggca ggacagccgc gctcaatgcc cttgtgccgg ccggcgctgt cacgttcaac 10261 gagggcggca cgcgtgaccc gttccgcttg cttggacccc gggacattga caagcagaac 10321 atgcttgaaa ttttccagcg cgtgcttgca tcgtcgggag acttggccgt ggcatcgtcc 10381 aactttgccc gttacgtggt ggcggcttcg ctgccccgtt acccgcaaat catcgacagg 10441 gtgaacggtg ttgccaccat cgtcaaagat ccgcttgtgc ccgagctgcc ggccggcagt 10501 atcgtcgccg gcccgatgca gaccgacata accaccatgg caaatcagat ccgcgtcgag 10561 taccgggttg tcaccgacac catggagcag accggtgatg atgccagcgc cgtctacgtc 10621 aacgccgagt cgctgacggc ctacggtgcc atggggcgaa gcatcagcac agatcttgcg 10681 acggttgccg gcagccgtgc cgaggacaaa gcacgccggc ttgccgagag ccaggcgcag 10741 ccgttctacc gtcttgctga caaggtacgg cttgtgtcgt cgcagatccc cgacgcgccg 10801 aacgtggcac ggctgtacag cgcggacatt ggctttgggc agctcattta cgtgcccgac 10861 gcgccggcag tgcttggcaa ctatcaccga gtcaggggag caaccctgac cttgggacgt 10921 gagccggccg ttgagctgga cgttgagccg ccggactatt cagcgccgga ggctttgacg 10981 ttcggcgaag cacgcaacac aacacccccg ttcaacattc tcaagctgtc cgagttccaa 11041 aacatcacca ttgggcagct caaatacgtc agtgcattgg aggaataaca agcatggatc 11101 tttcaggagc atttccgaaa ctgaccgatg ccgatagcgt ctacgcgatc aaggaataca 11161 gcgaacggat gtttaccgag ctggacaaga tgccgcgtgg actgattggc cggtctaacc 11221 tcaatggctc tacggccggc attggtgccg cgtcggtcat ggtggatctt gtggccgtgc 11281 cgctcgtggc cggccgttgg tacaaagtcg agtacgtctt gaccacggtg gccggcggac 11341 ccaatgacgc tatcgcctat gacttcaaaa agtcagcggt gaatgactcg tcagcggccg 11401 gcacgtcgtt gaatgacggc acgcaacgct acatctatac cggccccgct gccggcaact 11461 ccaagaccga agttattagg acggtgttca aggcaccgtc caacgaaacg caggtaatca 11521 aagcaatcct tgcccgggca acgggcagcg ttgcgtttac tgccaacagc cgtggccttt 11581 acgtgttcga tatggggaca acagcactat gacaacaatg acgcttgcct atccgctcgt 11641 tgagggcgag acaatccaag agttcggtgc ccgtcaatcg ttctaccgga agcttgggca 11701 gcttgggcat aacggcatcg accttggttg cgaggttggc accccggtct atgccatggc 11761 agccggcacc gtgctgcatg ccggttggtc ccacgatcac ccatggctga cccatcatgc 11821 cggcattgcc gtcctgactc accacggcga acacatcagc ggcctagcgc acctatccaa 11881 ggttgtggtg tctcccggtg accgtgtgga ggtcgggcag ctcgtcggct actcagggga 11941 cacagggacg gccggcgtgc cccatgtgca ctgtgagctg ttggcagcac agccggattg 12001 gtccaacggc tacgccggcc gcatccgttt cgagttcagc aaaggagagc taaattgaca 12061 taccagtacc tgacggggca gacaagcccg ttccagtcac cccgaaccca gcccatccaa 12121 tcaatcacca tccattggtg ggacaagccc gaacgtaacc cgacgttcca aggcaccgtt 12181 gattggttat gccgcattgg cacgactgcc agcatccact atgtggcaga ggccggccgc 12241 gtggcgtgcc ttgtggcccc tgaccgcatt gcatggcacg ccggggacgg tggccttggt 12301 gtagggaaca acaccagcat tggcattgag tgcaacccgc gtcagtctga cggcgactat 12361 cagactgttg ccgagcttgt gcgagacctc agggccgtct acggcaactt gcccatctat 12421 ccgcaccggc attggaccaa caccgagtgc ccaggcacct atgaccttgc ccgaatcaac 12481 cgactagccg caacgccggc accatcacag gaggacgaaa tgaaccccga acagaaccgc 12541 atgctcgttg cgctgtacaa cgcattcttc aacaagaaga gcttgccgac gccggacaat 12601 cagtccatcg tcggcggcga agcgatcgac gacttgatca acatcaatga caacaagatc 12661 cttgccgagc ttcgcgaaat caagaacaag ctctcatgag cgcgaagcca acgcccaaag 12721 tcgccgccgt cggcgtcagc ggcgctctca cagtcctaat cgtttgggta gcgggactct 12781 gcggcattga tatgccggca gaagtcgcgg ccgctatctc tgtagttgtt acgttcggtg 12841 ccggctacat caaaagcgag gtgacagagc gtgatggatc aggaggtgag cacgttgcca 12901 gatagcggca cttggaccca gcccgaggtt gtccgctcgt tacagcgcat tgagcgcaag 12961 cttgataacg ccgtaaccag ctcttatgta gaagctctga aagctgacca gcttcgcaag 13021 gacaacgagc aagacaaggc cattgaggct gtggagcaga accataacaa gctgctgctg 13081 ttggtggtca gcacggcact tggcagcgcg gcaagcctga ttgttgcatt ggcgtcagcg 13141 ctaccgaaat aggcgagaat gccccgtaac acctacaaag ggttgcgggg cattctgctg 13201 tcaacgtatt gttgacagca tggcaagcaa agcaaagtgt gaaacgacag aatacgccgg 13261 catgctgcgg cgcatgatcc gtgcctacgg ccggcgcgtt ggtgatgctg acgttgagga 13321 cttggccgtg atgctggaag tacagcgaga gcttgacgcg gctatccaag ctgccgtaga 13381 cagccagcga gagaaccacg gcaggagttg ggctgacatt gcccgggcaa ccggcacaag 13441 ccgccaagcc gcgcagaaga aatacggcgt ataacaaatt ttggatatgg ccttataggt 13501 tgttatatcc gtgcgacgtt ggggcggacg gccggccggc accgttcccc gaatagctca 13561 cccacagcac accccagcac gccggcgacc gtcaccagct cagaggcgaa ccatgggcgc 13621 tgcccgtgca gtttccggct gaccgtggct tgtgtcagtc cgagccgtgc cgctagatcc 13681 cattgagtca ttcccaacgc cgacagccgg cgctctatgc gcttgcctat gtcggcatca 13741 gtgcttgccg gccgtgcttg gactcgtgtg gtcatggcgc aaggttacga caagtaatga 13801 cattaatcac cacttgttta atccgctcgt gtactcgttt atccacgccg gctacttggt 13861 cagcgtgtcg taacttgtcg tttcatgccc gaggggtata gcgttcaggg catgacagag 13921 cattcaagcg aaacgacaga acttgtcgaa gctgcccaag ctgccgtgct gctgggagtc 13981 agcaagcgca ccttggacag gtaccaagcc gccggcctaa tcactcccat aaggcccata 14041 cagggcaaag gtgcaatacg ccggtttgac gctcaggacg tgcagcggct agccgtagct 14101 caggacggtc agccatgagc attgagtcaa tggccgtagt gcttcaccac agccaagccg 14161 gcggcactga caagcttgtg ctgctgggta tcgccaatca cgacggcgac ggcggctctt 14221 ggccgagcat tgcgacccta gcccggtatg ccaacgttga accccgagcc gtcaaagcgt 14281 gcatcaaccg tcttgtagcc cggggcgaag tcgagcgcga gcggcaagcc ggcggcaccc 14341 gcaacatgcc cgactacagc cggccgaacc tttaccacct caaagtggtc tgcccgccgg 14401 agtgtgaccg tagtgcacag caccgaatca acagaaaaga cccggtgtcg tcaacgacac 14461 ccggtgtcgt cacgataccc ccgggggggt acgttccaga tacccccggg ggggtacgcc 14521 caacgacacc caaaccatca actaaccatc cctataactc tgacaaatca cctagctcta 14581 gtacctcacc agcggaaaac ggcaagctgc cgtgctggaa ctgcggcgaa cacgtcattg 14641 ccaacaccac caagcccaag cgctactgtc agccgtgcag ctcccgagga cttgataacc 14701 cattgatccc atgcaagaaa tgcggctcag ttcgcaagcg agcattcccc ggggaacagg 14761 agttcgactg tggatgcgtt tgagccttac gaaacctact ccatggccgt cctatggaat 14821 atgggcatca gaaacgctca tgacgtacca ctagacggcg acgcaatggc acgccggcta 14881 gcggcagagc gagccgtgca gatccattgg cagaccgtat cgccggccca agtccaggca 14941 ctcaaagaca accaccacca agtagacaag gattcaagat catgatcagc actgagtcag 15001 tggagatagc acgcaagaca tccttggacg ctcaacacgt agccgagcta ttccaagacg 15061 ctatagacca agcccgagag acctacgtca acgactccaa gacggatacg tggagtgagt 15121 acatccacgc gttgagccag taccaagccg ctgcccgacg tgccacggct gcccgtctca 15181 tggccgatgc cgttgcccat gcctaccacc tagagcaagc atgggaacgg tgcaaggctc 15241 tgcccatcac gatcaatgct gcccggtgat tggggaggac gtgaggccca acgcctcaca 15301 gagttgtgca tggcgaccta cggttggacg tgccacctat gcaagcaacc cattaggcaa 15361 ggcgagcaaa gcgcagacca cctattgcca aggaagtggg gaggaagtaa tgacctatcg 15421 aacctcagac cggcacacag gaaatgcaac tatgcacgcg gtgccaagct gctgtcagat 15481 ccacgcgcaa ggccaacgga caacaccgcg ttttttaact gagggcggct ctggacaccc 15541 cgcgccacc //