locus-tag	class	description
OL239_00020	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
OL239_00045	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
OL239_00060	COG1846	Transcriptional regulator
OL239_00065	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OL239_00090	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OL239_00100	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OL239_00115	COG2315	Protein conserved in bacteria
OL239_00155	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OL239_00160	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OL239_00175	COG1832	CoA-binding protein
OL239_00190	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OL239_00205	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OL239_00220	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
OL239_00235	COG0800	Aldolase
OL239_00250	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OL239_00285	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
OL239_00380	COG0531	amino acid
OL239_00385	COG0857	belongs to the CobB CobQ family
OL239_00385	COG0280	phosphate acetyltransferase
OL239_00390	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
OL239_00415	COG3387	PFAM Glycoside hydrolase 15-related
OL239_00420	COG2733	membrane
OL239_00515	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
OL239_00565	COG1461	Dihydroxyacetone kinase
OL239_00575	COG3237	CsbD-like
OL239_00580	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
OL239_00610	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
OL239_00615	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
OL239_00645	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
OL239_00655	COG0302	gtp cyclohydrolase
OL239_00660	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OL239_00670	COG0037	tRNA processing
OL239_00680	COG2027	D-alanyl-D-alanine carboxypeptidase
OL239_00685	COG2027	D-alanyl-D-alanine carboxypeptidase
OL239_00690	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
OL239_00700	COG0561	phosphatase activity
OL239_00710	COG1597	lipid kinase activity
OL239_00730	COG0077	Prephenate dehydratase
OL239_00735	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OL239_00745	COG3104	oligopeptide transport
OL239_00760	COG1012	belongs to the aldehyde dehydrogenase family
OL239_00770	COG2233	PERMEase
OL239_00795	COG0584	glycerophosphoryl diester phosphodiesterase
OL239_00805	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
OL239_00810	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
OL239_00815	COG0671	phosphoesterase, PA-phosphatase related
OL239_00820	COG0561	phosphatase activity
OL239_00850	COG1609	Transcriptional regulator
OL239_00855	COG1028	Short-chain dehydrogenase reductase Sdr
OL239_00890	COG0351	phosphomethylpyrimidine kinase
OL239_00890	COG0352	thiamine-phosphate diphosphorylase activity
OL239_00890	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
OL239_00895	COG0352	thiamine-phosphate diphosphorylase activity
OL239_00970	COG0723	plastoquinol--plastocyanin reductase activity
OL239_00970	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OL239_00980	COG0783	Belongs to the Dps family
OL239_00985	COG2186	Transcriptional regulator
OL239_00990	COG3265	gluconokinase activity
OL239_00995	COG2610	gluconate transmembrane transporter activity
OL239_01005	COG0346	lactoylglutathione lyase activity
OL239_01045	COG0768	penicillin binding
OL239_01055	COG0515	serine threonine protein kinase
OL239_01055	COG2815	serine threonine protein kinase
OL239_01070	COG3764	Sortase (surface protein transpeptidase)
OL239_01080	COG0705	Rhomboid family
OL239_01120	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
OL239_01125	COG0187	DNA topoisomerase II activity
OL239_01130	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
OL239_01135	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
OL239_01140	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
OL239_01145	COG0592	DNA-directed DNA polymerase activity
OL239_01150	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
OL239_01155	COG0230	Belongs to the bacterial ribosomal protein bL34 family
OL239_01160	COG0594	ribonuclease P activity
OL239_01180	COG0357	Ribosomal RNA small subunit methyltransferase G
OL239_01185	COG1192	Involved in chromosome partitioning
OL239_01225	COG1215	transferase activity, transferring glycosyl groups
OL239_01230	COG3409	Peptidoglycan-binding domain 1 protein
OL239_01230	COG0860	N-Acetylmuramoyl-L-alanine amidase
OL239_01240	COG0492	ferredoxin-NADP+ reductase activity
OL239_01270	COG0617	tRNA 3'-terminal CCA addition
OL239_01275	COG0406	alpha-ribazole phosphatase activity
OL239_01280	COG0438	transferase activity, transferring glycosyl groups
OL239_01315	COG0488	(ABC) transporter
OL239_01340	COG1131	(ABC) transporter
OL239_01350	COG1362	aminopeptidase activity
OL239_01355	COG0360	Binds together with S18 to 16S ribosomal RNA
OL239_01365	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
OL239_01375	COG0305	Participates in initiation and elongation during chromosome replication
OL239_01390	COG3583	domain protein
OL239_01395	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
OL239_01410	COG2814	Major facilitator Superfamily
OL239_01415	COG0534	Mate efflux family protein
OL239_01450	COG1012	belongs to the aldehyde dehydrogenase family
OL239_01460	COG1028	Short-chain dehydrogenase reductase Sdr
OL239_01465	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
OL239_01465	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
OL239_01470	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
OL239_01475	COG0438	transferase activity, transferring glycosyl groups
OL239_01500	COG1191	sigma factor activity
OL239_01535	COG2610	gluconate transmembrane transporter activity
OL239_01540	COG0659	secondary active sulfate transmembrane transporter activity
OL239_01545	COG1595	DNA-templated transcription, initiation
OL239_01550	COG2169	Transcriptional regulator
OL239_01550	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OL239_01615	COG5002	protein histidine kinase activity
OL239_01625	COG2409	Drug exporters of the RND superfamily
OL239_01710	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
OL239_01730	COG0820	rRNA (adenine-C2-)-methyltransferase activity
OL239_01735	COG1695	Transcriptional regulator
OL239_01740	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
OL239_01760	COG1950	PFAM Membrane protein of
OL239_01775	COG0022	dehydrogenase e1 component
OL239_01780	COG0508	dehydrogenase complex catalyzes the overall conversion of
OL239_01790	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OL239_01795	COG2197	response regulator
OL239_01800	COG0698	ribose 5-phosphate isomerase
OL239_01805	COG0149	triose-phosphate isomerase activity
OL239_01810	COG2376	Dihydroxyacetone kinase
OL239_01835	COG1802	Transcriptional regulator
OL239_01840	COG2610	gluconate transmembrane transporter activity
OL239_01910	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
OL239_01930	COG1302	Protein conserved in bacteria
OL239_01955	COG1113	amino acid transport
OL239_01965	COG0404	The glycine cleavage system catalyzes the degradation of glycine
OL239_01970	COG0509	glycine decarboxylation via glycine cleavage system
OL239_01975	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
OL239_01995	COG1175	transmembrane transport
OL239_02010	COG1115	amino acid carrier protein
OL239_02015	COG1620	l-lactate permease
OL239_02020	COG0277	FAD linked oxidase domain protein
OL239_02060	COG1028	Short-chain dehydrogenase reductase Sdr
OL239_02080	COG1309	transcriptional regulator
OL239_02090	COG1175	transmembrane transport
OL239_02095	COG0395	ABC-type sugar transport system, permease component
OL239_02110	COG0667	Aldo Keto reductase
OL239_02125	COG2358	TRAP transporter, solute receptor (TAXI family
OL239_02145	COG1028	Short-chain dehydrogenase reductase Sdr
OL239_02170	COG0579	oxidoreductase
OL239_02175	COG3546	catalase activity
OL239_02185	COG3546	catalase activity
OL239_02200	COG0477	Major facilitator Superfamily
OL239_02215	COG0598	Magnesium transport protein CorA
OL239_02360	COG0492	ferredoxin-NADP+ reductase activity
OL239_02405	COG0531	amino acid
OL239_02410	COG2076	Multidrug Resistance protein
OL239_02415	COG2076	Multidrug Resistance protein
OL239_02425	COG0583	DNA-binding transcription factor activity
OL239_02430	COG1609	Transcriptional regulator
OL239_02435	COG0673	inositol 2-dehydrogenase activity
OL239_02450	COG3386	PFAM SMP-30 Gluconolaconase
OL239_02460	COG1072	(Pantothenic acid kinase))
OL239_02480	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
OL239_02490	COG1028	Short-chain dehydrogenase reductase Sdr
OL239_02520	COG0596	Alpha beta hydrolase
OL239_02540	COG0604	alcohol dehydrogenase
OL239_02560	COG0604	alcohol dehydrogenase
OL239_02650	COG1309	transcriptional regulator
OL239_02695	COG2860	membrane
OL239_02700	COG1012	belongs to the aldehyde dehydrogenase family
OL239_02710	COG5002	protein histidine kinase activity
OL239_02715	COG0596	Alpha beta hydrolase
OL239_02730	COG0028	Belongs to the TPP enzyme family
OL239_02750	COG4221	oxidoreductase activity
OL239_02760	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
OL239_02780	COG0583	DNA-binding transcription factor activity
OL239_02785	COG1012	belongs to the aldehyde dehydrogenase family
OL239_02815	COG4152	abc transporter atp-binding protein
OL239_02825	COG4585	Histidine kinase
OL239_02860	COG1174	glycine betaine transport
OL239_02870	COG1174	glycine betaine transport
OL239_02915	COG1960	acyl-CoA dehydrogenase activity
OL239_02920	COG1028	Short-chain dehydrogenase reductase Sdr
OL239_02955	COG1295	ribonuclease BN
OL239_02960	COG0492	ferredoxin-NADP+ reductase activity
OL239_02985	COG1120	ATPase activity
OL239_02995	COG0739	heme binding
OL239_02995	COG0741	lytic transglycosylase activity
OL239_02995	COG1196	nuclear chromosome segregation
OL239_03000	COG1597	lipid kinase activity
OL239_03010	COG0477	Major facilitator Superfamily
OL239_03030	COG0227	Belongs to the bacterial ribosomal protein bL28 family
OL239_03035	COG0267	Belongs to the bacterial ribosomal protein bL33 family
OL239_03040	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
OL239_03045	COG0776	regulation of translation
OL239_03115	COG3483	tryptophan 2,3-dioxygenase activity
OL239_03120	COG0717	Belongs to the dCTP deaminase family
OL239_03135	COG1006	Multisubunit Na H antiporter MnhC subunit
OL239_03140	COG0651	ATP synthesis coupled electron transport
OL239_03150	COG2212	antiporter activity
OL239_03185	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OL239_03190	COG0512	Glutamine amidotransferase of anthranilate synthase
OL239_03190	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
OL239_03205	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
OL239_03215	COG0789	Transcriptional regulator
OL239_03250	COG3304	Inner membrane component domain
OL239_03255	COG0768	penicillin binding
OL239_03265	COG1012	belongs to the aldehyde dehydrogenase family
OL239_03295	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
OL239_03330	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
OL239_03350	COG1132	(ABC) transporter
OL239_03360	COG1408	metallophosphoesterase
OL239_03395	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
OL239_03400	COG0477	Major facilitator Superfamily
OL239_03410	COG1764	response to oxidative stress
OL239_03415	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OL239_03460	COG4585	Histidine kinase
OL239_03510	COG1111	helicase
OL239_03510	COG1205	dead DEAH box helicase
OL239_03535	COG0477	Major facilitator Superfamily
OL239_03540	COG0477	Major facilitator Superfamily
OL239_03545	COG1012	belongs to the aldehyde dehydrogenase family
OL239_03565	COG1309	transcriptional regulator
OL239_03575	COG1960	acyl-CoA dehydrogenase activity
OL239_03580	COG1960	acyl-CoA dehydrogenase activity
OL239_03585	COG1053	succinate dehydrogenase
OL239_03590	COG2890	protein-(glutamine-N5) methyltransferase activity
OL239_03595	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OL239_03595	COG1754	DNA topoisomerase type I activity
OL239_03600	COG0248	Ppx GppA phosphatase
OL239_03605	COG1082	Xylose isomerase domain protein TIM barrel
OL239_03615	COG0569	domain protein
OL239_03630	COG0640	Transcriptional regulator
OL239_03635	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
OL239_03665	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
OL239_03685	COG2353	YceI-like domain
OL239_03690	COG0406	alpha-ribazole phosphatase activity
OL239_03700	COG0785	Cytochrome C biogenesis protein
OL239_03710	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
OL239_03735	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
OL239_03745	COG1140	nitrate reductase beta subunit
OL239_03770	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
OL239_03795	COG1024	Enoyl-CoA hydratase
OL239_03800	COG1250	3-hydroxyacyl-CoA dehydrogenase
OL239_03825	COG1793	dna ligase
OL239_03840	COG2030	dehydratase
OL239_03840	COG1012	belongs to the aldehyde dehydrogenase family
OL239_03850	COG1309	transcriptional regulator
OL239_03865	COG0586	Pfam SNARE associated Golgi protein
OL239_03880	COG3396	Phenylacetate-CoA oxygenase
OL239_03885	COG3460	Phenylacetate-CoA oxygenase
OL239_03895	COG2151	metal-sulfur cluster biosynthetic enzyme
OL239_03900	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OL239_03910	COG0415	Belongs to the DNA photolyase family
OL239_03935	COG2837	iron assimilation
OL239_03955	COG0022	dehydrogenase e1 component
OL239_04020	COG1011	Hydrolase
OL239_04055	COG1937	Protein conserved in bacteria
OL239_04075	COG0024	Methionine aminopeptidase
OL239_04095	COG0247	lactate metabolic process
OL239_04095	COG0277	FAD linked oxidase domain protein
OL239_04115	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OL239_04140	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
OL239_04145	COG0028	Belongs to the TPP enzyme family
OL239_04160	COG1126	abc transporter atp-binding protein
OL239_04165	COG0765	amino acid transport
OL239_04170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OL239_04175	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OL239_04185	COG2226	methyltransferase
OL239_04195	COG0142	geranyltranstransferase activity
OL239_04220	COG1012	belongs to the aldehyde dehydrogenase family
OL239_04310	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
OL239_04315	COG0142	geranyltranstransferase activity
OL239_04365	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OL239_04375	COG0501	Belongs to the peptidase M48B family
OL239_04380	COG0406	alpha-ribazole phosphatase activity
OL239_04390	COG1666	GTP binding
OL239_04405	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OL239_04425	COG0673	inositol 2-dehydrogenase activity
OL239_04445	COG1228	amidohydrolase
OL239_04455	COG5650	phosphatidylinositol metabolic process
OL239_04480	COG0515	serine threonine protein kinase
OL239_04480	COG2815	serine threonine protein kinase
OL239_04500	COG0693	protein deglycase activity
OL239_04515	COG2030	dehydratase
OL239_04525	COG0812	UDP-N-acetylmuramate dehydrogenase activity
OL239_04540	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
OL239_04550	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
OL239_04555	COG1528	Iron-storage protein
OL239_04560	COG2826	transposase and inactivated derivatives, IS30 family
OL239_04570	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
OL239_04575	COG0456	acetyltransferase
OL239_04595	COG3485	protocatechuate 3,4-dioxygenase
OL239_04645	COG0436	Aminotransferase
OL239_04665	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
OL239_04670	COG0081	regulation of translation
OL239_04690	COG2084	Dehydrogenase
OL239_04695	COG2610	gluconate transmembrane transporter activity
OL239_04705	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
OL239_04710	COG0222	ribosome binding
OL239_04720	COG0085	RNA polymerase activity
OL239_04725	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OL239_04730	COG3485	protocatechuate 3,4-dioxygenase
OL239_04735	COG3485	protocatechuate 3,4-dioxygenase
OL239_04750	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OL239_04755	COG0183	Belongs to the thiolase family
OL239_04765	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
OL239_04770	COG1414	Transcriptional regulator
OL239_04775	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
OL239_04780	COG0049	tRNA binding
OL239_04785	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
OL239_04790	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
OL239_04805	COG0051	transcription antitermination factor activity, RNA binding
OL239_04815	COG0088	Forms part of the polypeptide exit tunnel
OL239_04820	COG0089	rRNA binding
OL239_04825	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
OL239_04830	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
OL239_04835	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
OL239_04840	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
OL239_04845	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
OL239_04850	COG0255	Belongs to the universal ribosomal protein uL29 family
OL239_04855	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
OL239_04860	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
OL239_04870	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
OL239_04875	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
OL239_04880	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
OL239_04890	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
OL239_04895	COG1841	ribosomal large subunit assembly
OL239_04900	COG0200	Binds to the 23S rRNA
OL239_04910	COG0563	adenylate kinase activity
OL239_04920	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
OL239_04925	COG0257	Belongs to the bacterial ribosomal protein bL36 family
OL239_04930	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
OL239_04935	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
OL239_04945	COG0203	ribosomal protein L17
OL239_04950	COG0101	tRNA pseudouridine synthase activity
OL239_04955	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
OL239_04960	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
OL239_04965	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OL239_04970	COG1072	(Pantothenic acid kinase))
OL239_04975	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
OL239_05005	COG0667	Aldo Keto reductase
OL239_05010	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OL239_05030	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
OL239_05040	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
OL239_05055	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
OL239_05080	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
OL239_05090	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
OL239_05100	COG4604	ABC transporter, ATP-binding protein
OL239_05110	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OL239_05120	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
OL239_05125	COG0459	protein refolding
OL239_05140	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
OL239_05160	COG0519	Catalyzes the synthesis of GMP from XMP
OL239_05160	COG0518	GMP synthase (glutamine-hydrolyzing) activity
OL239_05185	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
OL239_05190	COG1210	Utp--glucose-1-phosphate uridylyltransferase
OL239_05225	COG2971	BadF BadG BcrA BcrD
OL239_05240	COG1174	glycine betaine transport
OL239_05245	COG1174	glycine betaine transport
OL239_05260	COG1722	exodeoxyribonuclease VII activity
OL239_05265	COG1570	exodeoxyribonuclease VII activity
OL239_05275	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
OL239_05280	COG0012	GTP binding
OL239_05320	COG1028	Short-chain dehydrogenase reductase Sdr
OL239_05330	COG3173	Aminoglycoside phosphotransferase
OL239_05340	COG0477	Major facilitator Superfamily
OL239_05345	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OL239_05385	COG0444	Belongs to the ABC transporter superfamily
OL239_05390	COG4608	Belongs to the ABC transporter superfamily
OL239_05410	COG4166	transmembrane transport
OL239_05415	COG0747	negative chemotaxis
OL239_05420	COG0601	transmembrane transport
OL239_05425	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OL239_05435	COG1217	gtp-binding protein TYPA
OL239_05465	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
OL239_05475	COG2171	N-acyltransferase activity
OL239_05480	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OL239_05485	COG0765	amino acid transport
OL239_05490	COG0765	amino acid transport
OL239_05495	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OL239_05500	COG1126	abc transporter atp-binding protein
OL239_05505	COG1611	Belongs to the LOG family
OL239_05530	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
OL239_05535	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
OL239_05545	COG1595	DNA-templated transcription, initiation
OL239_05555	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OL239_05570	COG2239	Acts as a magnesium transporter
OL239_05585	COG0613	PHP domain protein
OL239_05640	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
OL239_05655	COG3253	May function as heme-dependent peroxidase
OL239_05660	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
OL239_05665	COG0181	hydroxymethylbilane synthase activity
OL239_05675	COG0113	porphobilinogen synthase activity
OL239_05685	COG1464	Belongs to the NlpA lipoprotein family
OL239_05720	COG1074	ATP-dependent DNA helicase activity
OL239_05780	COG3480	Lon protease (S16) C-terminal proteolytic domain
OL239_05800	COG1842	Phage shock protein A
OL239_05810	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OL239_05825	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
OL239_05835	COG1595	DNA-templated transcription, initiation
OL239_05840	COG4106	trans-aconitate 2-methyltransferase activity
OL239_05870	COG0482	sulfurtransferase activity
OL239_05895	COG0714	Associated with various cellular activities
OL239_05915	COG0745	RESPONSE REGULATOR receiver
OL239_05920	COG5002	protein histidine kinase activity
OL239_05930	COG5401	PFAM Sporulation and spore germination
OL239_05940	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OL239_05945	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
OL239_05950	COG3214	Protein conserved in bacteria
OL239_06010	COG2755	lipolytic protein G-D-S-L family
OL239_06010	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
OL239_06070	COG0463	Glycosyl transferase, family 2
OL239_06075	COG1876	peptidase activity
OL239_06140	COG2177	Part of the ABC transporter FtsEX involved in
OL239_06180	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
OL239_06190	COG0483	inositol monophosphate 1-phosphatase activity
OL239_06200	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
OL239_06210	COG1595	DNA-templated transcription, initiation
OL239_06225	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OL239_06235	COG0747	negative chemotaxis
OL239_06245	COG0567	Dehydrogenase, E1 component
OL239_06245	COG0508	dehydrogenase complex catalyzes the overall conversion of
OL239_06250	COG1253	flavin adenine dinucleotide binding
OL239_06265	COG1121	(ABC) transporter
OL239_06290	COG0537	adenosine 5'-monophosphoramidase activity
OL239_06365	COG0577	efflux transmembrane transporter activity
OL239_06365	COG1136	(ABC) transporter
OL239_06390	COG0018	arginyl-trna synthetase
OL239_06410	COG0083	homoserine kinase activity
OL239_06420	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
OL239_06425	COG2890	protein-(glutamine-N5) methyltransferase activity
OL239_06475	COG0356	it plays a direct role in the translocation of protons across the membrane
OL239_06480	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OL239_06485	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
OL239_06495	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
OL239_06500	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
OL239_06510	COG0355	proton-transporting ATP synthase activity, rotational mechanism
OL239_06520	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OL239_06530	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
OL239_06560	COG1131	(ABC) transporter
OL239_06610	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
OL239_06620	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
OL239_06625	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
OL239_06650	COG0420	3'-5' exonuclease activity
OL239_06655	COG0419	ATPase involved in DNA repair
OL239_06670	COG0515	serine threonine protein kinase
OL239_06670	COG2815	serine threonine protein kinase
OL239_06685	COG1113	amino acid transport
OL239_06690	COG1522	sequence-specific DNA binding
OL239_06700	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
OL239_06705	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
OL239_06715	COG1104	cysteine desulfurase activity
OL239_06720	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OL239_06735	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OL239_06740	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OL239_06745	COG0579	oxidoreductase
OL239_06750	COG0747	negative chemotaxis
OL239_06760	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OL239_06765	COG0601	transmembrane transport
OL239_06770	COG0747	negative chemotaxis
OL239_06820	COG0129	dihydroxy-acid dehydratase activity
OL239_06830	COG0440	acetolactate synthase activity
OL239_06835	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
OL239_06840	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
OL239_06845	COG1136	(ABC) transporter
OL239_06845	COG0577	efflux transmembrane transporter activity
OL239_06865	COG1088	dTDP-glucose 4,6-dehydratase activity
OL239_06880	COG1136	(ABC) transporter
OL239_06880	COG0577	efflux transmembrane transporter activity
OL239_06890	COG1136	(ABC) transporter
OL239_06890	COG0577	efflux transmembrane transporter activity
OL239_06895	COG2197	response regulator
OL239_06900	COG4585	Histidine kinase
OL239_06935	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OL239_07045	COG0546	phosphoglycolate phosphatase activity
OL239_07070	COG1414	Transcriptional regulator
OL239_07075	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
OL239_07080	COG0066	3-isopropylmalate dehydratase activity
OL239_07085	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OL239_07095	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
OL239_07100	COG1181	Belongs to the D-alanine--D-alanine ligase family
OL239_07110	COG1316	TRANSCRIPTIONal
OL239_07135	COG1682	transport, permease protein
OL239_07140	COG1134	teichoic acid transport
OL239_07155	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
OL239_07160	COG0438	transferase activity, transferring glycosyl groups
OL239_07205	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
OL239_07220	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
OL239_07245	COG0742	ribosomal rna small subunit methyltransferase
OL239_07265	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
OL239_07290	COG0333	Belongs to the bacterial ribosomal protein bL32 family
OL239_07295	COG0571	ribonuclease III activity
OL239_07305	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
OL239_07310	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OL239_07320	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OL239_07335	COG0477	Major facilitator Superfamily
OL239_07375	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
OL239_07400	COG2514	catechol 2,3-dioxygenase activity
OL239_07410	COG0228	four-way junction DNA binding
OL239_07415	COG1837	Belongs to the UPF0109 family
OL239_07420	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
OL239_07425	COG0336	Belongs to the RNA methyltransferase TrmD family
OL239_07430	COG0335	large ribosomal subunit rRNA binding
OL239_07435	COG0681	Belongs to the peptidase S26 family
OL239_07445	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
OL239_07475	COG0792	nuclease activity
OL239_07495	COG4974	Belongs to the 'phage' integrase family
OL239_07505	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
OL239_07510	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OL239_07515	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OL239_07545	COG2186	Transcriptional regulator
OL239_07555	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
OL239_07590	COG1045	serine acetyltransferase
OL239_07600	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OL239_07605	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
OL239_07620	COG3022	response to hydroperoxide
OL239_07720	COG1609	Transcriptional regulator
OL239_07725	COG0395	ABC-type sugar transport system, permease component
OL239_07730	COG4209	transmembrane transport
OL239_07740	COG1472	Belongs to the glycosyl hydrolase 3 family
OL239_07755	COG0629	single-stranded DNA binding
OL239_07770	COG1946	Acyl-CoA thioesterase
OL239_07790	COG0668	transmembrane transport
OL239_07815	COG0698	ribose 5-phosphate isomerase
OL239_07850	COG0544	peptidyl-prolyl cis-trans isomerase activity
OL239_07860	COG0740	serine-type endopeptidase activity
OL239_07870	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
OL239_07880	COG3189	MarR family transcriptional regulator
OL239_07905	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
OL239_07910	COG0285	dihydrofolate synthase activity
OL239_07920	COG0105	UTP biosynthetic process
OL239_07950	COG0261	This protein binds to 23S rRNA in the presence of protein L20
OL239_07955	COG0211	Belongs to the bacterial ribosomal protein bL27 family
OL239_07960	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
OL239_07965	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
OL239_07970	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
OL239_07980	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
OL239_07995	COG0588	phosphoglycerate mutase activity
OL239_08050	COG1780	Probably involved in ribonucleotide reductase function
OL239_08060	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OL239_08135	COG0702	epimerase
OL239_08165	COG1028	Short-chain dehydrogenase reductase Sdr
OL239_08200	COG2135	peptidase activity
OL239_08210	COG0656	L-ascorbic acid biosynthetic process
OL239_08225	COG3103	Sh3 type 3 domain protein
OL239_08225	COG0366	Alpha amylase catalytic
OL239_08265	COG2409	Drug exporters of the RND superfamily
OL239_08270	COG2409	Drug exporters of the RND superfamily
OL239_08305	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
OL239_08315	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OL239_08350	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
OL239_08355	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
OL239_08360	COG0217	transcriptional regulatory protein
OL239_08365	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
OL239_08370	COG0632	four-way junction helicase activity
OL239_08385	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OL239_08390	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OL239_08395	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OL239_08415	COG0124	histidyl-tRNA synthetase
OL239_08420	COG2197	response regulator
OL239_08455	COG0384	phenazine biosynthesis protein PhzF
OL239_08495	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
OL239_08500	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
OL239_08520	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
OL239_08525	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
OL239_08530	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
OL239_08535	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OL239_08545	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
OL239_08555	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
OL239_08565	COG0505	Belongs to the CarA family
OL239_08575	COG0284	orotidine-5'-phosphate decarboxylase activity
OL239_08580	COG0194	GDP metabolic process
OL239_08585	COG0194	GDP metabolic process
OL239_08590	COG1758	RNA polymerase activity
OL239_08600	COG2826	transposase and inactivated derivatives, IS30 family
OL239_08605	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
OL239_08670	COG0596	Alpha beta hydrolase
OL239_08685	COG0494	nUDIX hydrolase
OL239_08700	COG2130	NADP-dependent
OL239_08705	COG0438	transferase activity, transferring glycosyl groups
OL239_08710	COG0596	Alpha beta hydrolase
OL239_08720	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
OL239_08725	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
OL239_08740	COG2072	flavoprotein involved in K transport
OL239_08750	COG0385	Bile acid
OL239_08755	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OL239_08770	COG0495	leucyl-tRNA aminoacylation
OL239_08775	COG1307	EDD domain protein, DegV family
OL239_08780	COG1555	photosystem II stabilization
OL239_08780	COG1596	polysaccharide export
OL239_08805	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OL239_08815	COG0268	Binds directly to 16S ribosomal RNA
OL239_08825	COG0481	GTPase activity
OL239_08845	COG1420	regulation of RNA biosynthetic process
OL239_08850	COG0484	heat shock protein binding
OL239_08870	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
OL239_08880	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
OL239_08885	COG1316	TRANSCRIPTIONal
OL239_08905	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
OL239_08915	COG0167	dihydroorotate dehydrogenase activity
OL239_08945	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
OL239_08950	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OL239_08960	COG2188	Transcriptional regulator
OL239_08975	COG0723	plastoquinol--plastocyanin reductase activity
OL239_08985	COG1845	cytochrome c oxidase, subunit III
OL239_08990	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
OL239_09025	COG1609	Transcriptional regulator
OL239_09035	COG1028	Short-chain dehydrogenase reductase Sdr
OL239_09035	COG3347	Dehydrogenase
OL239_09040	COG1070	Carbohydrate kinase
OL239_09065	COG1403	HNH endonuclease
OL239_09070	COG1028	Short-chain dehydrogenase reductase Sdr
OL239_09075	COG1028	Short-chain dehydrogenase reductase Sdr
OL239_09085	COG1940	carbohydrate kinase activity
OL239_09095	COG4166	transmembrane transport
OL239_09115	COG0444	Belongs to the ABC transporter superfamily
OL239_09130	COG3250	beta-galactosidase activity
OL239_09145	COG1940	carbohydrate kinase activity
OL239_09150	COG0667	Aldo Keto reductase
OL239_09160	COG0425	Belongs to the sulfur carrier protein TusA family
OL239_09165	COG2391	methyltransferase activity
OL239_09190	COG1012	belongs to the aldehyde dehydrogenase family
OL239_09200	COG1024	Enoyl-CoA hydratase
OL239_09230	COG0488	(ABC) transporter
OL239_09260	COG1607	acyl-coa hydrolase
OL239_09265	COG1028	Short-chain dehydrogenase reductase Sdr
OL239_09270	COG1472	Belongs to the glycosyl hydrolase 3 family
OL239_09275	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
OL239_09280	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
OL239_09290	COG2066	Belongs to the glutaminase family
OL239_09295	COG2066	Belongs to the glutaminase family
OL239_09300	COG0076	glutamate decarboxylase activity
OL239_09310	COG0477	Major facilitator Superfamily
OL239_09330	COG1902	pentaerythritol trinitrate reductase activity
OL239_09350	COG2050	protein possibly involved in aromatic compounds catabolism
OL239_09360	COG4552	Acetyltransferase involved in intracellular survival and related
OL239_09365	COG0539	negative regulation of cytoplasmic translation
OL239_09400	COG1970	mechanosensitive ion channel activity
OL239_09420	COG3655	Transcriptional regulator
OL239_09430	COG2890	protein-(glutamine-N5) methyltransferase activity
OL239_09435	COG1739	Uncharacterized protein family UPF0029
OL239_09440	COG0237	dephospho-CoA kinase activity
OL239_09440	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
OL239_09445	COG0556	nucleotide-excision repair
OL239_09480	COG0531	amino acid
OL239_09485	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OL239_09525	COG1660	Displays ATPase and GTPase activities
OL239_09535	COG1481	regulation of sporulation
OL239_09565	COG0363	glucosamine-6-phosphate deaminase activity
OL239_09580	COG0166	Belongs to the GPI family
OL239_09610	COG1131	(ABC) transporter
OL239_09635	COG2151	metal-sulfur cluster biosynthetic enzyme
OL239_09645	COG1122	ATPase activity
OL239_09650	COG1268	BioY protein
OL239_09700	COG1028	Short-chain dehydrogenase reductase Sdr
OL239_09730	COG0254	rRNA binding
OL239_09735	COG0095	Lipoate-protein ligase
OL239_09750	COG2855	membrane
OL239_09755	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
OL239_09775	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
OL239_09785	COG2826	transposase and inactivated derivatives, IS30 family
OL239_09800	COG0183	Belongs to the thiolase family
OL239_09805	COG1028	Short-chain dehydrogenase reductase Sdr
OL239_09810	COG2030	dehydratase
OL239_09820	COG4213	ABC transporter substrate-binding protein
OL239_09825	COG1129	ABC transporter
OL239_09830	COG4214	carbohydrate transport
OL239_09835	COG0589	response to stress
OL239_09855	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OL239_09875	COG1968	undecaprenyl-diphosphatase activity
OL239_09880	COG0215	cysteine-tRNA ligase activity
OL239_09905	COG1222	aaa ATPase
OL239_09920	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
OL239_09960	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OL239_09965	COG0805	protein transport
OL239_10015	COG0242	peptide deformylase activity
OL239_10030	COG4974	Belongs to the 'phage' integrase family
OL239_10070	COG4941	Belongs to the sigma-70 factor family
OL239_10100	COG1175	transmembrane transport
OL239_10110	COG1609	Transcriptional regulator
OL239_10125	COG1175	transmembrane transport
OL239_10165	COG0697	spore germination
OL239_10175	COG0473	3-isopropylmalate dehydrogenase activity
OL239_10195	COG0471	metal ion transport
OL239_10225	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
OL239_10235	COG2197	response regulator
OL239_10250	COG1136	(ABC) transporter
OL239_10255	COG2017	converts alpha-aldose to the beta-anomer
OL239_10260	COG1609	Transcriptional regulator
OL239_10275	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
OL239_10295	COG0277	FAD linked oxidase domain protein
OL239_10325	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OL239_10350	COG0009	L-threonylcarbamoyladenylate synthase
OL239_10400	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
OL239_10425	COG0366	Alpha amylase catalytic
OL239_10430	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
OL239_10440	COG2072	flavoprotein involved in K transport
OL239_10445	COG2072	flavoprotein involved in K transport
OL239_10455	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
OL239_10470	COG1028	Short-chain dehydrogenase reductase Sdr
OL239_10475	COG1028	Short-chain dehydrogenase reductase Sdr
OL239_10480	COG1024	Enoyl-CoA hydratase
OL239_10520	COG1960	acyl-CoA dehydrogenase activity
OL239_10525	COG1024	Enoyl-CoA hydratase
OL239_10530	COG1960	acyl-CoA dehydrogenase activity
OL239_10535	COG1960	acyl-CoA dehydrogenase activity
OL239_10540	COG1960	acyl-CoA dehydrogenase activity
OL239_10555	COG1309	transcriptional regulator
OL239_10565	COG0318	PFAM AMP-dependent synthetase and ligase
OL239_10595	COG1024	Enoyl-CoA hydratase
OL239_10610	COG0318	PFAM AMP-dependent synthetase and ligase
OL239_10630	COG1960	acyl-CoA dehydrogenase activity
OL239_10635	COG1960	acyl-CoA dehydrogenase activity
OL239_10650	COG0488	(ABC) transporter
OL239_10690	COG2814	Major facilitator Superfamily
OL239_10705	COG0577	efflux transmembrane transporter activity
OL239_10705	COG1136	(ABC) transporter
OL239_10720	COG2197	response regulator
OL239_10740	COG2205	protein histidine kinase activity
OL239_10745	COG0745	RESPONSE REGULATOR receiver
OL239_10770	COG2890	protein-(glutamine-N5) methyltransferase activity
OL239_10780	COG2072	flavoprotein involved in K transport
OL239_10820	COG5650	phosphatidylinositol metabolic process
OL239_10845	COG1028	Short-chain dehydrogenase reductase Sdr
OL239_10865	COG3971	2-oxopent-4-enoate hydratase activity
OL239_10875	COG1012	belongs to the aldehyde dehydrogenase family
OL239_10985	COG2116	formate transmembrane transporter activity
OL239_10990	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
OL239_11015	COG0628	permease
OL239_11060	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
OL239_11080	COG3226	Transcriptional regulator
OL239_11155	COG1253	flavin adenine dinucleotide binding
OL239_11180	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
OL239_11225	COG0789	Transcriptional regulator
OL239_11225	COG4978	Transcriptional regulator
OL239_11235	COG4106	trans-aconitate 2-methyltransferase activity
OL239_11325	COG2197	response regulator
OL239_11335	COG2826	transposase and inactivated derivatives, IS30 family
OL239_11340	COG2826	transposase and inactivated derivatives, IS30 family
OL239_11365	COG3012	SEC-C Motif Domain Protein
OL239_11390	COG0488	(ABC) transporter
OL239_11415	COG1902	pentaerythritol trinitrate reductase activity
OL239_11470	COG1414	Transcriptional regulator
OL239_11530	COG2211	Major facilitator Superfamily
OL239_11550	COG0702	epimerase
OL239_11575	COG1262	PFAM Formylglycine-generating sulfatase enzyme
OL239_11595	COG0010	Belongs to the arginase family
OL239_11620	COG1733	regulation of RNA biosynthetic process
OL239_11635	COG0174	glutamine synthetase
OL239_11715	COG2323	membrane
OL239_11745	COG0656	L-ascorbic acid biosynthetic process
OL239_11770	COG3226	Transcriptional regulator
OL239_11800	COG1846	Transcriptional regulator
OL239_11805	COG1132	(ABC) transporter
OL239_11830	COG1329	Transcriptional regulator
OL239_11835	COG1309	transcriptional regulator
OL239_11840	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OL239_11855	COG2124	cytochrome p450
OL239_11875	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OL239_11885	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OL239_11990	COG1309	transcriptional regulator
OL239_12010	COG1108	ABC-type Mn2 Zn2 transport systems permease components
OL239_12015	COG1121	(ABC) transporter
OL239_12035	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OL239_12075	COG1172	Belongs to the binding-protein-dependent transport system permease family
OL239_12085	COG2188	Transcriptional regulator
OL239_12090	COG0673	inositol 2-dehydrogenase activity
OL239_12095	COG1082	Xylose isomerase domain protein TIM barrel
OL239_12100	COG3718	enzyme involved in inositol metabolism
OL239_12105	COG2814	Major facilitator Superfamily
OL239_12110	COG1082	Xylose isomerase domain protein TIM barrel
OL239_12115	COG0673	inositol 2-dehydrogenase activity
OL239_12155	COG0469	pyruvate kinase activity
OL239_12185	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
OL239_12190	COG0159	tryptophan synthase activity
OL239_12200	COG0134	indole-3-glycerol-phosphate synthase activity
OL239_12220	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
OL239_12225	COG4221	oxidoreductase activity
OL239_12250	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
OL239_12255	COG1064	alcohol dehydrogenase
OL239_12270	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
OL239_12275	COG0140	phosphoribosyl-ATP diphosphatase activity
OL239_12280	COG0596	Alpha beta hydrolase
OL239_12285	COG0596	Alpha beta hydrolase
OL239_12305	COG3833	ABC-type maltose transport systems, permease component
OL239_12310	COG1175	transmembrane transport
OL239_12320	COG4221	oxidoreductase activity
OL239_12340	COG1129	ABC transporter
OL239_12365	COG0477	Major facilitator Superfamily
OL239_12370	COG2814	Major facilitator Superfamily
OL239_12395	COG1122	ATPase activity
OL239_12400	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
OL239_12405	COG0477	Major facilitator Superfamily
OL239_12420	COG0589	response to stress
OL239_12425	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
OL239_12430	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OL239_12430	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OL239_12450	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
OL239_12465	COG0242	peptide deformylase activity
OL239_12540	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
OL239_12555	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OL239_12585	COG1269	ATP hydrolysis coupled proton transport
OL239_12605	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
OL239_12630	COG0183	Belongs to the thiolase family
OL239_12635	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
OL239_12685	COG0456	acetyltransferase
OL239_12685	COG0454	-acetyltransferase
OL239_12715	COG0395	ABC-type sugar transport system, permease component
OL239_12720	COG1175	transmembrane transport
OL239_12800	COG1024	Enoyl-CoA hydratase
OL239_12800	COG1250	3-hydroxyacyl-CoA dehydrogenase
OL239_12805	COG0667	Aldo Keto reductase
OL239_12860	COG0756	dUTP diphosphatase activity
OL239_12880	COG1435	thymidine kinase activity
OL239_12900	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
OL239_12915	COG1937	Protein conserved in bacteria
OL239_12950	COG4988	ABC transporter
OL239_12955	COG1294	oxidase, subunit
OL239_13005	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
OL239_13010	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OL239_13015	COG0508	dehydrogenase complex catalyzes the overall conversion of
OL239_13025	COG1764	response to oxidative stress
OL239_13030	COG0831	urea catabolic process
OL239_13040	COG0832	Belongs to the urease beta subunit family
OL239_13050	COG0830	nickel cation binding
OL239_13060	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
OL239_13065	COG0829	nickel cation binding
OL239_13070	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
OL239_13085	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OL239_13110	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
OL239_13145	COG1126	abc transporter atp-binding protein
OL239_13160	COG0174	glutamine synthetase
OL239_13185	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
OL239_13190	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
OL239_13200	COG1511	domain protein
OL239_13220	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
OL239_13225	COG3599	regulation of cell shape
OL239_13235	COG1799	cell septum assembly
OL239_13240	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
OL239_13250	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
OL239_13275	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
OL239_13280	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OL239_13295	COG0768	penicillin binding
OL239_13310	COG2001	Belongs to the MraZ family
OL239_13320	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OL239_13345	COG2815	serine threonine protein kinase
OL239_13345	COG0515	serine threonine protein kinase
OL239_13350	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
OL239_13370	COG1940	carbohydrate kinase activity
OL239_13410	COG1716	ATPase activity
OL239_13420	COG0300	oxidoreductase activity
OL239_13480	COG0464	growth
OL239_13510	COG1160	GTP binding
OL239_13515	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
OL239_13530	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
OL239_13535	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
OL239_13550	COG3290	protein histidine kinase activity
OL239_13555	COG3290	protein histidine kinase activity
OL239_13580	COG2079	MmgE PrpD family protein
OL239_13585	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
OL239_13620	COG0494	nUDIX hydrolase
OL239_13625	COG0504	CTP synthase activity
OL239_13635	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
OL239_13675	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OL239_13685	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
OL239_13715	COG0259	pyridoxamine-phosphate oxidase activity
OL239_13720	COG0165	Argininosuccinate lyase
OL239_13725	COG0137	argininosuccinate synthase activity
OL239_13730	COG1438	arginine binding
OL239_13735	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
OL239_13740	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OL239_13745	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
OL239_13750	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
OL239_13755	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
OL239_13775	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
OL239_13790	COG0072	phenylalanine-tRNA ligase activity
OL239_13790	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OL239_13795	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
OL239_13820	COG2814	Major facilitator Superfamily
OL239_13830	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
OL239_13835	COG0291	Belongs to the bacterial ribosomal protein bL35 family
OL239_13840	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
OL239_13875	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
OL239_13895	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
OL239_13905	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
OL239_13915	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
OL239_13920	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
OL239_13950	COG2137	regulation of response to DNA damage stimulus
OL239_13955	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
OL239_13970	COG1396	sequence-specific DNA binding
OL239_13975	COG1546	Belongs to the CinA family
OL239_13975	COG1058	Belongs to the CinA family
OL239_13985	COG1674	ftsk spoiiie
OL239_13990	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
OL239_13995	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OL239_14010	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
OL239_14040	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
OL239_14065	COG1185	polyribonucleotide nucleotidyltransferase activity
OL239_14070	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
OL239_14095	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
OL239_14110	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
OL239_14115	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
OL239_14145	COG0442	prolyl-tRNA aminoacylation
OL239_14165	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
OL239_14185	COG0750	zinc metalloprotease
OL239_14190	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
OL239_14195	COG0702	epimerase
OL239_14220	COG1960	acyl-CoA dehydrogenase activity
OL239_14245	COG2826	transposase and inactivated derivatives, IS30 family
OL239_14270	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OL239_14285	COG3279	Response regulator of the LytR AlgR family
OL239_14290	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OL239_14305	COG0233	cytoplasmic translational termination
OL239_14310	COG0528	UMP kinase activity
OL239_14315	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
OL239_14320	COG0052	Belongs to the universal ribosomal protein uS2 family
OL239_14340	COG0297	glycogen (starch) synthase activity
OL239_14360	COG0477	Major facilitator Superfamily
OL239_14415	COG0423	glycine-tRNA ligase activity
OL239_14425	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OL239_14445	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OL239_14465	COG3250	beta-galactosidase activity
OL239_14475	COG1228	amidohydrolase
OL239_14505	COG1254	Belongs to the acylphosphatase family
OL239_14525	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OL239_14530	COG0154	amidase activity
OL239_14535	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OL239_14545	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
OL239_14565	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OL239_14570	COG0601	transmembrane transport
OL239_14590	COG2226	methyltransferase
OL239_14645	COG1674	ftsk spoiiie
OL239_14650	COG1674	ftsk spoiiie
OL239_14660	COG0631	protein serine/threonine phosphatase activity
OL239_14680	COG1028	Short-chain dehydrogenase reductase Sdr
OL239_14685	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OL239_14700	COG1823	symporter activity
OL239_14705	COG0424	maF-like protein
OL239_14725	COG0477	Major facilitator Superfamily
OL239_14740	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OL239_14765	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
OL239_14805	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
OL239_14850	COG2205	protein histidine kinase activity
OL239_14870	COG5002	protein histidine kinase activity
OL239_14900	COG0822	iron-sulfur transferase activity
OL239_15000	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
OL239_15055	COG0193	aminoacyl-tRNA hydrolase activity
OL239_15060	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
OL239_15065	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OL239_15100	COG0488	(ABC) transporter
OL239_15130	COG0084	hydrolase, TatD family'
OL239_15175	COG1022	Amp-dependent synthetase and ligase
OL239_15200	COG1376	ErfK ybiS ycfS ynhG family protein
OL239_15205	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
OL239_15270	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
OL239_15275	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
OL239_15290	COG1316	TRANSCRIPTIONal
OL239_15305	COG2826	transposase and inactivated derivatives, IS30 family
OL239_15330	COG1494	fructose-1,6-bisphosphatase
OL239_15340	COG0288	reversible hydration of carbon dioxide
OL239_15355	COG0477	Major facilitator Superfamily
OL239_15375	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
OL239_15385	COG1331	Highly conserved protein containing a thioredoxin domain
OL239_15395	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
OL239_15405	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
OL239_15410	COG0705	Rhomboid family
OL239_15415	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
OL239_15425	COG2017	converts alpha-aldose to the beta-anomer
OL239_15440	COG1129	ABC transporter
OL239_15445	COG1609	Transcriptional regulator
OL239_15460	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OL239_15495	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
OL239_15500	COG0586	Pfam SNARE associated Golgi protein
OL239_15520	COG4603	Belongs to the binding-protein-dependent transport system permease family
OL239_15525	COG3845	ABC transporter
OL239_15530	COG1744	ABC transporter substrate-binding protein PnrA-like
OL239_15540	COG0662	Cupin 2, conserved barrel domain protein
OL239_15540	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
OL239_15545	COG2009	succinate dehydrogenase
OL239_15560	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
OL239_15575	COG0180	Tryptophanyl-tRNA synthetase
OL239_15615	COG1131	(ABC) transporter
OL239_15690	COG0138	bifunctional purine biosynthesis protein purh
OL239_15775	COG0531	amino acid
OL239_15785	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
OL239_15800	COG0753	catalase activity
OL239_15820	COG0831	urea catabolic process
OL239_15825	COG0832	Belongs to the urease beta subunit family
OL239_15830	COG0804	urea catabolic process
OL239_15835	COG0830	nickel cation binding
OL239_15845	COG0829	nickel cation binding
OL239_15850	COG1108	ABC-type Mn2 Zn2 transport systems permease components
OL239_15865	COG0596	Alpha beta hydrolase
OL239_15870	COG0471	metal ion transport
OL239_15880	COG1174	glycine betaine transport
OL239_15890	COG1174	glycine betaine transport
OL239_15895	COG1063	alcohol dehydrogenase
OL239_15900	COG1063	alcohol dehydrogenase
OL239_15905	COG1063	alcohol dehydrogenase
OL239_15910	COG3012	SEC-C Motif Domain Protein
OL239_15920	COG0515	serine threonine protein kinase
OL239_15940	COG1012	belongs to the aldehyde dehydrogenase family
OL239_15945	COG1028	Short-chain dehydrogenase reductase Sdr
OL239_15960	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OL239_15965	COG0601	transmembrane transport
OL239_15970	COG0747	negative chemotaxis
OL239_15975	COG2186	Transcriptional regulator
OL239_15980	COG1278	Cold shock
OL239_15985	COG2066	Belongs to the glutaminase family
OL239_15985	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
OL239_15990	COG1278	Cold shock
OL239_16035	COG0346	lactoylglutathione lyase activity
OL239_16045	COG1414	Transcriptional regulator
OL239_16055	COG4569	acetaldehyde dehydrogenase (acetylating) activity
OL239_16060	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OL239_16085	COG1053	succinate dehydrogenase
OL239_16085	COG3976	FMN-binding domain protein
OL239_16090	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OL239_16110	COG0039	L-malate dehydrogenase activity
OL239_16130	COG4172	Belongs to the ABC transporter superfamily
OL239_16140	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OL239_16155	COG0747	negative chemotaxis
OL239_16160	COG3619	membrane
OL239_16170	COG1620	l-lactate permease
OL239_16180	COG0683	leucine binding
OL239_16220	COG1609	Transcriptional regulator
OL239_16225	COG0579	oxidoreductase
OL239_16230	COG0579	oxidoreductase
OL239_16235	COG0589	response to stress
OL239_16255	COG0583	DNA-binding transcription factor activity
OL239_16260	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OL239_16270	COG4948	Mandelate Racemase Muconate Lactonizing
OL239_16300	COG0247	lactate metabolic process
OL239_16305	COG1620	l-lactate permease
OL239_16315	COG2188	Transcriptional regulator
OL239_16320	COG1546	Belongs to the CinA family
OL239_16320	COG1058	Belongs to the CinA family
OL239_16345	COG0693	protein deglycase activity
OL239_16350	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OL239_16355	COG0584	glycerophosphoryl diester phosphodiesterase
OL239_16385	COG2814	Major facilitator Superfamily
OL239_16390	COG3458	cephalosporin-C deacetylase activity
OL239_16410	COG2826	transposase and inactivated derivatives, IS30 family
OL239_16420	COG1070	Carbohydrate kinase
OL239_16425	COG2115	Belongs to the xylose isomerase family
OL239_16460	COG2072	flavoprotein involved in K transport
OL239_16470	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OL239_16475	COG0798	PFAM Bile acid sodium symporter
OL239_16480	COG0640	Transcriptional regulator
OL239_16490	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OL239_16505	COG1063	alcohol dehydrogenase
OL239_16560	COG1349	DNA-binding transcription factor activity
OL239_16575	COG1175	transmembrane transport
OL239_16580	COG0395	ABC-type sugar transport system, permease component
OL239_16600	COG0747	negative chemotaxis
OL239_16610	COG0601	transmembrane transport
OL239_16625	COG1960	acyl-CoA dehydrogenase activity
OL239_16685	COG1120	ATPase activity
OL239_16690	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OL239_16695	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OL239_16705	COG0667	Aldo Keto reductase
OL239_16710	COG0583	DNA-binding transcription factor activity
OL239_16730	COG3949	Membrane
OL239_16735	COG2235	arginine
OL239_16760	COG2235	arginine
OL239_16825	COG0406	alpha-ribazole phosphatase activity
OL239_16830	COG3842	ATPase activity
OL239_16835	COG1178	ABC-type Fe3 transport system permease component
OL239_16840	COG1840	ABC-type Fe3 transport system, periplasmic component
OL239_16845	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
OL239_16850	COG2365	Tyrosine phosphatase family
OL239_16865	COG1609	Transcriptional regulator
OL239_16870	COG3534	alpha-L-arabinofuranosidase
OL239_16880	COG1175	transmembrane transport
OL239_16885	COG0395	ABC-type sugar transport system, permease component
OL239_16890	COG0395	ABC-type sugar transport system, permease component
OL239_16900	COG1280	lysine exporter protein (LysE YggA)
OL239_16915	COG1172	Belongs to the binding-protein-dependent transport system permease family
OL239_16925	COG1879	ABC-type sugar transport system periplasmic component
OL239_16945	COG4214	carbohydrate transport
OL239_16950	COG1129	ABC transporter
OL239_16970	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OL239_16970	COG1017	nitric oxide dioxygenase activity
OL239_16980	COG1028	Short-chain dehydrogenase reductase Sdr
OL239_17025	COG1609	Transcriptional regulator
OL239_17030	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
OL239_17040	COG4770	biotin carboxylase activity
OL239_17050	COG4336	lyase activity
OL239_17055	COG1914	H( )-stimulated, divalent metal cation uptake system
OL239_17070	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OL239_17080	COG0640	Transcriptional regulator
OL239_17115	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
OL239_17120	COG1940	carbohydrate kinase activity
OL239_17125	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OL239_17130	COG4608	Belongs to the ABC transporter superfamily
OL239_17135	COG0444	Belongs to the ABC transporter superfamily
OL239_17145	COG0747	negative chemotaxis
OL239_17160	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
OL239_17175	COG1874	Beta-galactosidase
OL239_17195	COG0395	ABC-type sugar transport system, permease component
OL239_17205	COG1472	Belongs to the glycosyl hydrolase 3 family
OL239_17210	COG1472	Belongs to the glycosyl hydrolase 3 family
OL239_17220	COG3458	cephalosporin-C deacetylase activity
OL239_17240	COG2367	Beta-lactamase
OL239_17255	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OL239_17260	COG1116	anion transmembrane transporter activity
OL239_17265	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OL239_17290	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OL239_17295	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
OL239_17305	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OL239_17315	COG0583	DNA-binding transcription factor activity
OL239_17325	COG0477	Major facilitator Superfamily
OL239_17340	COG0154	amidase activity
OL239_17350	COG1404	Belongs to the peptidase S8 family
OL239_17405	COG1957	nucleoside hydrolase
OL239_17410	COG0477	Major facilitator Superfamily
OL239_17415	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OL239_17425	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OL239_17450	COG0252	asparaginase activity
OL239_17490	COG3655	Transcriptional regulator
OL239_17525	COG3424	synthase
OL239_17530	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
OL239_17565	COG1396	sequence-specific DNA binding
OL239_17570	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OL239_17590	COG0656	L-ascorbic acid biosynthetic process
OL239_17610	COG2814	Major facilitator Superfamily
OL239_17620	COG0045	succinate-CoA ligase (ADP-forming) activity
OL239_17630	COG0483	inositol monophosphate 1-phosphatase activity
OL239_17640	COG2409	Drug exporters of the RND superfamily
OL239_17660	COG5002	protein histidine kinase activity
OL239_17665	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
OL239_17670	COG0303	'Molybdopterin
OL239_17705	COG0739	heme binding
OL239_17710	COG1321	iron dependent repressor
OL239_17730	COG1278	Cold shock
OL239_17750	COG0745	RESPONSE REGULATOR receiver
OL239_17755	COG2205	protein histidine kinase activity
OL239_17765	COG0459	protein refolding
OL239_17770	COG1278	Cold shock
OL239_17830	COG0667	Aldo Keto reductase
OL239_17835	COG3833	ABC-type maltose transport systems, permease component
OL239_17840	COG1175	transmembrane transport
OL239_17855	COG1609	Transcriptional regulator
OL239_17875	COG0318	PFAM AMP-dependent synthetase and ligase
OL239_17890	COG3547	Transposase (IS116 IS110 IS902 family)
OL239_17960	COG3621	Patatin-like phospholipase
OL239_17980	COG1940	carbohydrate kinase activity
OL239_18035	COG0366	Alpha amylase catalytic
OL239_18080	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
OL239_18085	COG0366	Alpha amylase catalytic
OL239_18090	COG0366	Alpha amylase catalytic
OL239_18115	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
OL239_18120	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
OL239_18140	COG5002	protein histidine kinase activity
OL239_18150	COG0588	phosphoglycerate mutase activity
OL239_18170	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
OL239_18200	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
OL239_18210	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
OL239_18215	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
OL239_18230	COG1338	Plays a role in the flagellum-specific transport system
OL239_18240	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
OL239_18240	COG1776	CheC inhibitor of MCP methylation
OL239_18255	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
OL239_18270	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
OL239_18295	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
OL239_18300	COG1766	The M ring may be actively involved in energy transduction
OL239_18305	COG1677	Flagellar hook-basal body complex protein FliE
OL239_18310	COG1558	bacterial-type flagellum-dependent cell motility
OL239_18315	COG1815	bacterial-type flagellum-dependent cell motility
OL239_18340	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
OL239_18345	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OL239_18365	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
OL239_18370	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
OL239_18375	COG0656	L-ascorbic acid biosynthetic process
OL239_18405	COG0604	alcohol dehydrogenase
OL239_18415	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
OL239_18425	COG0395	ABC-type sugar transport system, permease component
OL239_18430	COG1175	transmembrane transport
OL239_18445	COG3250	beta-galactosidase activity
OL239_18460	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OL239_18480	COG0789	Transcriptional regulator
OL239_18505	COG1505	serine-type exopeptidase activity
OL239_18515	COG0667	Aldo Keto reductase
OL239_18525	COG1024	Enoyl-CoA hydratase
OL239_18550	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
OL239_18565	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OL239_18585	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
OL239_18605	COG4589	Belongs to the CDS family
OL239_18650	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
OL239_18685	COG0564	pseudouridine synthase activity
OL239_18715	COG1960	acyl-CoA dehydrogenase activity
OL239_18765	COG0343	queuine tRNA-ribosyltransferase activity
OL239_18790	COG0351	phosphomethylpyrimidine kinase
OL239_18805	COG1216	Glycosyl transferase, family 2
OL239_18820	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
OL239_18825	COG1396	sequence-specific DNA binding
OL239_18830	COG2224	Isocitrate lyase
OL239_18835	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
OL239_18860	COG0673	inositol 2-dehydrogenase activity
OL239_18865	COG0673	inositol 2-dehydrogenase activity
OL239_18885	COG0583	DNA-binding transcription factor activity
OL239_18900	COG1120	ATPase activity
OL239_18905	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OL239_18945	COG0604	alcohol dehydrogenase
OL239_18965	COG0702	epimerase
OL239_18980	COG2235	arginine
OL239_18985	COG2235	arginine
OL239_18995	COG0628	permease
OL239_19035	COG2199	diguanylate cyclase activity
OL239_19035	COG2200	EAL domain
OL239_19075	COG0028	Belongs to the TPP enzyme family
OL239_19175	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
OL239_19175	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OL239_19185	COG3548	integral membrane protein