locus-tag	class	description
AUT26_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AUT26_00010	COG0592	DNA-directed DNA polymerase activity
AUT26_00015	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
AUT26_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AUT26_00025	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
AUT26_00030	COG0187	DNA topoisomerase II activity
AUT26_00040	COG3266	domain, Protein
AUT26_00055	COG3525	Glycosyl hydrolase, family 20, catalytic domain
AUT26_00055	COG3291	Pkd domain containing protein
AUT26_00065	COG1215	transferase activity, transferring glycosyl groups
AUT26_00080	COG0705	Rhomboid family
AUT26_00080	COG0457	Tetratricopeptide repeat
AUT26_00090	COG2818	Glycosylase
AUT26_00095	COG3145	DNA-N1-methyladenine dioxygenase activity
AUT26_00100	COG2169	Transcriptional regulator
AUT26_00100	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AUT26_00105	COG1595	DNA-templated transcription, initiation
AUT26_00120	COG3764	Sortase (surface protein transpeptidase)
AUT26_00130	COG0515	serine threonine protein kinase
AUT26_00135	COG0515	serine threonine protein kinase
AUT26_00140	COG0768	penicillin binding
AUT26_00155	COG1716	ATPase activity
AUT26_00160	COG1716	ATPase activity
AUT26_00200	COG2963	transposase activity
AUT26_00220	COG0346	lactoylglutathione lyase activity
AUT26_00235	COG2801	Transposase and inactivated derivatives
AUT26_00235	COG3415	Transposase
AUT26_00240	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AUT26_00245	COG0477	Major facilitator Superfamily
AUT26_00250	COG1984	allophanate hydrolase subunit 2
AUT26_00255	COG4770	biotin carboxylase activity
AUT26_00260	COG0277	FAD linked oxidase domain protein
AUT26_00265	COG0659	secondary active sulfate transmembrane transporter activity
AUT26_00285	COG0435	Glutathione S-transferase
AUT26_00290	COG0561	phosphatase activity
AUT26_00300	COG0584	glycerophosphoryl diester phosphodiesterase
AUT26_00305	COG3250	beta-galactosidase activity
AUT26_00310	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AUT26_00315	COG1929	Belongs to the glycerate kinase type-1 family
AUT26_00325	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AUT26_00335	COG0693	protein deglycase activity
AUT26_00345	COG3655	Transcriptional regulator
AUT26_00355	COG2233	PERMEase
AUT26_00360	COG0778	Nitroreductase
AUT26_00375	COG3104	oligopeptide transport
AUT26_00385	COG3340	Belongs to the peptidase S51 family
AUT26_00390	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AUT26_00390	COG0425	Belongs to the sulfur carrier protein TusA family
AUT26_00395	COG0077	Prephenate dehydratase
AUT26_00405	COG1597	lipid kinase activity
AUT26_00410	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AUT26_00415	COG0561	phosphatase activity
AUT26_00435	COG1191	sigma factor activity
AUT26_00440	COG0859	PFAM glycosyl transferase family 9
AUT26_00445	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AUT26_00450	COG0859	PFAM glycosyl transferase family 9
AUT26_00460	COG0438	transferase activity, transferring glycosyl groups
AUT26_00465	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AUT26_00470	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AUT26_00470	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AUT26_00485	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AUT26_00485	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AUT26_00550	COG0037	tRNA processing
AUT26_00565	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AUT26_00570	COG0302	gtp cyclohydrolase
AUT26_00580	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AUT26_00610	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AUT26_00615	COG2814	Major facilitator Superfamily
AUT26_00650	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AUT26_00660	COG0542	response to heat
AUT26_00665	COG1819	glycosyl
AUT26_00670	COG0823	Involved in the tonB-independent uptake of proteins
AUT26_00670	COG1506	peptidase
AUT26_00670	COG4946	Tricorn protease homolog
AUT26_00675	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AUT26_00690	COG2376	Dihydroxyacetone kinase
AUT26_00695	COG1461	Dihydroxyacetone kinase
AUT26_00700	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
AUT26_00705	COG3237	CsbD-like
AUT26_00760	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
AUT26_00765	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AUT26_00770	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AUT26_00775	COG3559	Exporter of polyketide antibiotics
AUT26_00835	COG0671	phosphoesterase, PA-phosphatase related
AUT26_00860	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AUT26_00910	COG0831	urea catabolic process
AUT26_00915	COG0832	Belongs to the urease beta subunit family
AUT26_00920	COG0804	urea catabolic process
AUT26_00925	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
AUT26_00930	COG0830	nickel cation binding
AUT26_00935	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AUT26_00940	COG0829	nickel cation binding
AUT26_00945	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
AUT26_00950	COG1595	DNA-templated transcription, initiation
AUT26_00965	COG2706	6-phosphogluconolactonase activity
AUT26_00970	COG0656	L-ascorbic acid biosynthetic process
AUT26_00980	COG0667	Aldo Keto reductase
AUT26_00995	COG3360	Dodecin
AUT26_01000	COG1028	Short-chain dehydrogenase reductase Sdr
AUT26_01010	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
AUT26_01020	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AUT26_01040	COG2186	Transcriptional regulator
AUT26_01055	COG2084	Dehydrogenase
AUT26_01060	COG2610	gluconate transmembrane transporter activity
AUT26_01115	COG3486	L-lysine 6-monooxygenase (NADPH) activity
AUT26_01130	COG0300	oxidoreductase activity
AUT26_01150	COG0697	spore germination
AUT26_01155	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AUT26_01160	COG2186	Transcriptional regulator
AUT26_01170	COG1175	transmembrane transport
AUT26_01180	COG4948	Mandelate Racemase Muconate Lactonizing
AUT26_01195	COG0477	Major facilitator Superfamily
AUT26_01200	COG2890	protein-(glutamine-N5) methyltransferase activity
AUT26_01220	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
AUT26_01255	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AUT26_01255	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AUT26_01255	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AUT26_01285	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AUT26_01305	COG1609	Transcriptional regulator
AUT26_01310	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AUT26_01360	COG0142	geranyltranstransferase activity
AUT26_01365	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
AUT26_01385	COG3842	ATPase activity
AUT26_01395	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AUT26_01400	COG3384	dioxygenase
AUT26_01410	COG1414	Transcriptional regulator
AUT26_01415	COG3971	2-oxopent-4-enoate hydratase activity
AUT26_01445	COG0179	Fumarylacetoacetate (FAA) hydrolase
AUT26_01460	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AUT26_01480	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AUT26_01490	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AUT26_01495	COG1028	Short-chain dehydrogenase reductase Sdr
AUT26_01500	COG1902	pentaerythritol trinitrate reductase activity
AUT26_01505	COG1309	transcriptional regulator
AUT26_01510	COG0318	PFAM AMP-dependent synthetase and ligase
AUT26_01515	COG0179	Fumarylacetoacetate (FAA) hydrolase
AUT26_01520	COG4770	biotin carboxylase activity
AUT26_01525	COG2301	Belongs to the HpcH HpaI aldolase family
AUT26_01535	COG1309	transcriptional regulator
AUT26_01550	COG0477	Major facilitator Superfamily
AUT26_01555	COG0028	Belongs to the TPP enzyme family
AUT26_01565	COG0673	inositol 2-dehydrogenase activity
AUT26_01570	COG0673	inositol 2-dehydrogenase activity
AUT26_01580	COG0673	inositol 2-dehydrogenase activity
AUT26_01595	COG2828	Protein conserved in bacteria
AUT26_01615	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AUT26_01620	COG1984	allophanate hydrolase subunit 2
AUT26_01625	COG2733	membrane
AUT26_01680	COG1028	Short-chain dehydrogenase reductase Sdr
AUT26_01700	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AUT26_01720	COG2902	Dehydrogenase
AUT26_01730	COG0010	Belongs to the arginase family
AUT26_01735	COG2252	PERMEase
AUT26_01760	COG3848	Pyruvate phosphate dikinase
AUT26_01760	COG0574	Belongs to the PEP-utilizing enzyme family
AUT26_01775	COG1609	Transcriptional regulator
AUT26_01815	COG1802	Transcriptional regulator
AUT26_01825	COG0395	ABC-type sugar transport system, permease component
AUT26_01830	COG1175	transmembrane transport
AUT26_01835	COG1285	pathogenesis
AUT26_01900	COG2182	Extracellular solute-binding protein
AUT26_01920	COG1609	Transcriptional regulator
AUT26_01940	COG2197	response regulator
AUT26_01960	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AUT26_01970	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AUT26_01995	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AUT26_02005	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AUT26_02015	COG1063	alcohol dehydrogenase
AUT26_02025	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AUT26_02030	COG3404	Formiminotransferase-cyclodeaminase
AUT26_02045	COG1802	Transcriptional regulator
AUT26_02055	COG0683	leucine binding
AUT26_02080	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AUT26_02085	COG0174	glutamine synthetase
AUT26_02095	COG1473	amidohydrolase
AUT26_02105	COG0583	DNA-binding transcription factor activity
AUT26_02130	COG0415	Belongs to the DNA photolyase family
AUT26_02140	COG1024	Enoyl-CoA hydratase
AUT26_02175	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AUT26_02180	COG1960	acyl-CoA dehydrogenase activity
AUT26_02195	COG0789	Transcriptional regulator
AUT26_02210	COG1609	Transcriptional regulator
AUT26_02225	COG0747	negative chemotaxis
AUT26_02235	COG0444	Belongs to the ABC transporter superfamily
AUT26_02250	COG0673	inositol 2-dehydrogenase activity
AUT26_02255	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AUT26_02275	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AUT26_02275	COG3608	succinylglutamate desuccinylase aspartoacylase
AUT26_02300	COG3384	dioxygenase
AUT26_02310	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AUT26_02320	COG1024	Enoyl-CoA hydratase
AUT26_02360	COG2159	amidohydrolase
AUT26_02375	COG1063	alcohol dehydrogenase
AUT26_02385	COG4336	lyase activity
AUT26_02390	COG1840	ABC-type Fe3 transport system, periplasmic component
AUT26_02415	COG1012	belongs to the aldehyde dehydrogenase family
AUT26_02420	COG2084	Dehydrogenase
AUT26_02430	COG2814	Major facilitator Superfamily
AUT26_02450	COG2124	cytochrome p450
AUT26_02455	COG1178	ABC-type Fe3 transport system permease component
AUT26_02465	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
AUT26_02475	COG1609	Transcriptional regulator
AUT26_02480	COG1904	glucuronate isomerase
AUT26_02485	COG0246	Mannitol dehydrogenase
AUT26_02495	COG4948	Mandelate Racemase Muconate Lactonizing
AUT26_02505	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AUT26_02540	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AUT26_02540	COG0357	Ribosomal RNA small subunit methyltransferase G
AUT26_02565	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AUT26_02575	COG2814	Major facilitator Superfamily
AUT26_02580	COG3386	PFAM SMP-30 Gluconolaconase
AUT26_02585	COG1846	Transcriptional regulator
AUT26_02605	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AUT26_02610	COG0673	inositol 2-dehydrogenase activity
AUT26_02615	COG1126	abc transporter atp-binding protein
AUT26_02620	COG0765	amino acid transport
AUT26_02630	COG1609	Transcriptional regulator
AUT26_02635	COG0477	Major facilitator Superfamily
AUT26_02660	COG2271	Major facilitator Superfamily
AUT26_02670	COG0129	dihydroxy-acid dehydratase activity
AUT26_02685	COG1621	beta-fructofuranosidase activity
AUT26_02700	COG1175	transmembrane transport
AUT26_02705	COG0395	ABC-type sugar transport system, permease component
AUT26_02730	COG1832	CoA-binding protein
AUT26_02740	COG2315	Protein conserved in bacteria
AUT26_02750	COG1175	transmembrane transport
AUT26_02770	COG3706	GGDEF domain
AUT26_02785	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AUT26_02790	COG0047	phosphoribosylformylglycinamidine synthase activity
AUT26_02810	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AUT26_02820	COG1404	Belongs to the peptidase S8 family
AUT26_02850	COG1846	Transcriptional regulator
AUT26_02865	COG5416	Lipopolysaccharide assembly protein A domain
AUT26_02895	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AUT26_02910	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AUT26_02925	COG1012	belongs to the aldehyde dehydrogenase family
AUT26_02945	COG0739	heme binding
AUT26_02945	COG1196	nuclear chromosome segregation
AUT26_02945	COG0741	lytic transglycosylase activity
AUT26_02975	COG1309	transcriptional regulator
AUT26_02995	COG0395	ABC-type sugar transport system, permease component
AUT26_03010	COG0438	transferase activity, transferring glycosyl groups
AUT26_03025	COG0589	response to stress
AUT26_03045	COG3290	protein histidine kinase activity
AUT26_03050	COG4565	transcriptional regulatory protein
AUT26_03060	COG2855	membrane
AUT26_03090	COG0673	inositol 2-dehydrogenase activity
AUT26_03120	COG1476	TRANSCRIPTIONal
AUT26_03125	COG1309	transcriptional regulator
AUT26_03135	COG0351	phosphomethylpyrimidine kinase
AUT26_03145	COG2205	protein histidine kinase activity
AUT26_03150	COG0745	RESPONSE REGULATOR receiver
AUT26_03155	COG0477	Major facilitator Superfamily
AUT26_03175	COG1309	transcriptional regulator
AUT26_03185	COG0343	queuine tRNA-ribosyltransferase activity
AUT26_03205	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AUT26_03215	COG0477	Major facilitator Superfamily
AUT26_03220	COG2508	Transcriptional regulator
AUT26_03225	COG0477	Major facilitator Superfamily
AUT26_03230	COG0028	Belongs to the TPP enzyme family
AUT26_03235	COG1012	belongs to the aldehyde dehydrogenase family
AUT26_03240	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AUT26_03245	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AUT26_03265	COG3842	ATPase activity
AUT26_03290	COG1960	acyl-CoA dehydrogenase activity
AUT26_03315	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AUT26_03325	COG1215	transferase activity, transferring glycosyl groups
AUT26_03340	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AUT26_03350	COG0586	Pfam SNARE associated Golgi protein
AUT26_03360	COG0564	pseudouridine synthase activity
AUT26_03375	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AUT26_03380	COG2364	Membrane
AUT26_03385	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AUT26_03390	COG1201	RNA secondary structure unwinding
AUT26_03470	COG0438	transferase activity, transferring glycosyl groups
AUT26_03475	COG0590	tRNA wobble adenosine to inosine editing
AUT26_03480	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AUT26_03510	COG2062	phosphohistidine phosphatase, SixA
AUT26_03515	COG0583	DNA-binding transcription factor activity
AUT26_03520	COG0697	spore germination
AUT26_03530	COG1309	transcriptional regulator
AUT26_03535	COG1511	domain protein
AUT26_03540	COG1129	ABC transporter
AUT26_03550	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
AUT26_03555	COG1940	carbohydrate kinase activity
AUT26_03560	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AUT26_03565	COG4608	Belongs to the ABC transporter superfamily
AUT26_03570	COG0444	Belongs to the ABC transporter superfamily
AUT26_03575	COG0601	transmembrane transport
AUT26_03580	COG0747	negative chemotaxis
AUT26_03600	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
AUT26_03605	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AUT26_03605	COG1017	nitric oxide dioxygenase activity
AUT26_03620	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AUT26_03625	COG0514	ATP-dependent DNA helicase (RecQ)
AUT26_03645	COG1505	serine-type exopeptidase activity
AUT26_03655	COG1113	amino acid transport
AUT26_03670	COG0604	alcohol dehydrogenase
AUT26_03670	COG3321	synthase
AUT26_03670	COG1028	Short-chain dehydrogenase reductase Sdr
AUT26_03680	COG1966	Carbon starvation protein
AUT26_03700	COG0656	L-ascorbic acid biosynthetic process
AUT26_03755	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AUT26_03760	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AUT26_03780	COG0588	phosphoglycerate mutase activity
AUT26_03790	COG5002	protein histidine kinase activity
AUT26_03810	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AUT26_03815	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AUT26_03825	COG0215	cysteine-tRNA ligase activity
AUT26_03860	COG0366	Alpha amylase catalytic
AUT26_03870	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AUT26_03900	COG0277	FAD linked oxidase domain protein
AUT26_03930	COG3842	ATPase activity
AUT26_03960	COG0475	glutathione-regulated potassium exporter activity
AUT26_03965	COG1028	Short-chain dehydrogenase reductase Sdr
AUT26_03980	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AUT26_03985	COG0588	phosphoglycerate mutase activity
AUT26_04025	COG0579	oxidoreductase
AUT26_04045	COG2957	Belongs to the agmatine deiminase family
AUT26_04050	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AUT26_04060	COG3634	alkyl hydroperoxide reductase activity
AUT26_04085	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
AUT26_04095	COG4786	Flagellar basal body rod
AUT26_04095	COG1256	bacterial-type flagellum assembly
AUT26_04105	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AUT26_04125	COG1473	amidohydrolase
AUT26_04135	COG1815	bacterial-type flagellum-dependent cell motility
AUT26_04145	COG1677	Flagellar hook-basal body complex protein FliE
AUT26_04150	COG1766	The M ring may be actively involved in energy transduction
AUT26_04155	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AUT26_04165	COG1157	protein secretion by the type III secretion system
AUT26_04175	COG0791	NLP P60 protein
AUT26_04195	COG3550	peptidyl-serine autophosphorylation
AUT26_04210	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AUT26_04215	COG1360	Flagellar Motor Protein
AUT26_04235	COG1338	Plays a role in the flagellum-specific transport system
AUT26_04240	COG1987	bacterial-type flagellum assembly
AUT26_04250	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AUT26_04255	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AUT26_04265	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
AUT26_04280	COG0477	Major facilitator Superfamily
AUT26_04295	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AUT26_04300	COG0509	glycine decarboxylation via glycine cleavage system
AUT26_04305	COG1760	l-serine dehydratase
AUT26_04310	COG1864	DNA RNA non-specific endonuclease
AUT26_04310	COG3591	Belongs to the peptidase S1B family
AUT26_04325	COG0577	efflux transmembrane transporter activity
AUT26_04325	COG1136	(ABC) transporter
AUT26_04350	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AUT26_04370	COG2801	Transposase and inactivated derivatives
AUT26_04370	COG3415	Transposase
AUT26_04375	COG0459	protein refolding
AUT26_04390	COG2205	protein histidine kinase activity
AUT26_04395	COG0745	RESPONSE REGULATOR receiver
AUT26_04415	COG2132	Multicopper oxidase
AUT26_04440	COG1278	Cold shock
AUT26_04460	COG0739	heme binding
AUT26_04465	COG1388	LysM domain
AUT26_04465	COG0791	NLP P60 protein
AUT26_04465	COG3103	Sh3 type 3 domain protein
AUT26_04480	COG0746	molybdenum cofactor guanylyltransferase activity
AUT26_04490	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AUT26_04510	COG1126	abc transporter atp-binding protein
AUT26_04515	COG0765	amino acid transport
AUT26_04520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AUT26_04535	COG0488	(ABC) transporter
AUT26_04540	COG1132	(ABC) transporter
AUT26_04575	COG0483	inositol monophosphate 1-phosphatase activity
AUT26_04590	COG0045	succinate-CoA ligase (ADP-forming) activity
AUT26_04600	COG1942	4-Oxalocrotonate Tautomerase
AUT26_04605	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AUT26_04615	COG3962	Belongs to the TPP enzyme family
AUT26_04630	COG0673	inositol 2-dehydrogenase activity
AUT26_04635	COG1082	Xylose isomerase domain protein TIM barrel
AUT26_04640	COG3718	enzyme involved in inositol metabolism
AUT26_04655	COG1172	Belongs to the binding-protein-dependent transport system permease family
AUT26_04665	COG0673	inositol 2-dehydrogenase activity
AUT26_04705	COG1396	sequence-specific DNA binding
AUT26_04715	COG0028	Belongs to the TPP enzyme family
AUT26_04745	COG3142	Participates in the control of copper homeostasis
AUT26_04755	COG1401	restriction endodeoxyribonuclease activity
AUT26_04770	COG2205	protein histidine kinase activity
AUT26_04785	COG1012	belongs to the aldehyde dehydrogenase family
AUT26_04790	COG1028	Short-chain dehydrogenase reductase Sdr
AUT26_04800	COG1024	Enoyl-CoA hydratase
AUT26_04805	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AUT26_04820	COG1396	sequence-specific DNA binding
AUT26_04840	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AUT26_04865	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AUT26_04870	COG1902	pentaerythritol trinitrate reductase activity
AUT26_04885	COG2376	Dihydroxyacetone kinase
AUT26_04890	COG0698	ribose 5-phosphate isomerase
AUT26_04895	COG1250	3-hydroxyacyl-CoA dehydrogenase
AUT26_04900	COG1028	Short-chain dehydrogenase reductase Sdr
AUT26_04905	COG2271	Major facilitator Superfamily
AUT26_04910	COG0149	triose-phosphate isomerase activity
AUT26_04945	COG1984	allophanate hydrolase subunit 2
AUT26_04950	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AUT26_04955	COG0439	Biotin carboxylase
AUT26_04960	COG0511	ligase activity, forming carbon-carbon bonds
AUT26_04970	COG3835	regulator
AUT26_04985	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AUT26_04995	COG1254	Belongs to the acylphosphatase family
AUT26_05000	COG0640	Transcriptional regulator
AUT26_05005	COG0402	S-adenosylhomocysteine deaminase activity
AUT26_05035	COG0477	Major facilitator Superfamily
AUT26_05050	COG3973	AAA domain
AUT26_05070	COG0861	Integral membrane protein TerC family
AUT26_05140	COG2072	flavoprotein involved in K transport
AUT26_05160	COG0577	efflux transmembrane transporter activity
AUT26_05160	COG1136	(ABC) transporter
AUT26_05190	COG4942	peptidase
AUT26_05195	COG1278	Cold shock
AUT26_05225	COG0789	Transcriptional regulator
AUT26_05230	COG0071	Belongs to the small heat shock protein (HSP20) family
AUT26_05265	COG2271	Major facilitator Superfamily
AUT26_05270	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AUT26_05280	COG0138	bifunctional purine biosynthesis protein purh
AUT26_05290	COG2838	Isocitrate dehydrogenase
AUT26_05305	COG0673	inositol 2-dehydrogenase activity
AUT26_05315	COG1136	(ABC) transporter
AUT26_05315	COG0577	efflux transmembrane transporter activity
AUT26_05320	COG1136	(ABC) transporter
AUT26_05320	COG0577	efflux transmembrane transporter activity
AUT26_05325	COG4213	ABC transporter substrate-binding protein
AUT26_05330	COG4214	carbohydrate transport
AUT26_05335	COG1129	ABC transporter
AUT26_05345	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AUT26_05360	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AUT26_05365	COG0531	amino acid
AUT26_05390	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AUT26_05395	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AUT26_05425	COG0180	Tryptophanyl-tRNA synthetase
AUT26_05455	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AUT26_05470	COG2009	succinate dehydrogenase
AUT26_05480	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AUT26_05480	COG1473	amidohydrolase
AUT26_05485	COG1846	Transcriptional regulator
AUT26_05490	COG1764	response to oxidative stress
AUT26_05495	COG2130	NADP-dependent
AUT26_05540	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AUT26_05550	COG0148	phosphopyruvate hydratase activity
AUT26_05575	COG1252	NADH dehydrogenase
AUT26_05615	COG0559	Belongs to the binding-protein-dependent transport system permease family
AUT26_05625	COG0183	Belongs to the thiolase family
AUT26_05630	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AUT26_05640	COG2017	converts alpha-aldose to the beta-anomer
AUT26_05650	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AUT26_05660	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AUT26_05670	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AUT26_05680	COG1331	Highly conserved protein containing a thioredoxin domain
AUT26_05690	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AUT26_05695	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AUT26_05715	COG0114	fumarate hydratase activity
AUT26_05720	COG0288	reversible hydration of carbon dioxide
AUT26_05730	COG1494	fructose-1,6-bisphosphatase
AUT26_05740	COG1482	cell wall glycoprotein biosynthetic process
AUT26_05750	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AUT26_05800	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AUT26_05855	COG0714	Associated with various cellular activities
AUT26_05860	COG0084	hydrolase, TatD family'
AUT26_05865	COG3583	domain protein
AUT26_05870	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AUT26_05875	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AUT26_05880	COG0488	(ABC) transporter
AUT26_05890	COG1309	transcriptional regulator
AUT26_05900	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AUT26_05905	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AUT26_05910	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AUT26_05915	COG0193	aminoacyl-tRNA hydrolase activity
AUT26_05940	COG0822	iron-sulfur transferase activity
AUT26_05945	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AUT26_05960	COG0702	epimerase
AUT26_05970	COG1988	membrane-bound metal-dependent
AUT26_05990	COG0297	glycogen (starch) synthase activity
AUT26_06005	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AUT26_06010	COG0446	pyridine nucleotide-disulphide oxidoreductase
AUT26_06050	COG1028	Short-chain dehydrogenase reductase Sdr
AUT26_06060	COG2814	Major facilitator Superfamily
AUT26_06065	COG2824	Alkylphosphonate utilization operon protein PhnA
AUT26_06070	COG0659	secondary active sulfate transmembrane transporter activity
AUT26_06090	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AUT26_06100	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AUT26_06105	COG1621	beta-fructofuranosidase activity
AUT26_06135	COG0243	molybdopterin cofactor binding
AUT26_06140	COG2223	nitrite transmembrane transporter activity
AUT26_06145	COG0477	Major facilitator Superfamily
AUT26_06150	COG4770	biotin carboxylase activity
AUT26_06155	COG0424	maF-like protein
AUT26_06160	COG2409	Drug exporters of the RND superfamily
AUT26_06165	COG1309	transcriptional regulator
AUT26_06195	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AUT26_06230	COG0714	Associated with various cellular activities
AUT26_06270	COG1674	ftsk spoiiie
AUT26_06280	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AUT26_06285	COG0483	inositol monophosphate 1-phosphatase activity
AUT26_06300	COG0251	oxidation-reduction process
AUT26_06305	COG4565	transcriptional regulatory protein
AUT26_06315	COG2851	Citrate transporter
AUT26_06320	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AUT26_06325	COG0154	amidase activity
AUT26_06330	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AUT26_06335	COG4209	transmembrane transport
AUT26_06340	COG0395	ABC-type sugar transport system, permease component
AUT26_06355	COG0673	inositol 2-dehydrogenase activity
AUT26_06365	COG1063	alcohol dehydrogenase
AUT26_06370	COG0156	8-amino-7-oxononanoate synthase activity
AUT26_06380	COG1228	amidohydrolase
AUT26_06385	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AUT26_06390	COG1940	carbohydrate kinase activity
AUT26_06400	COG0191	fructose-bisphosphate aldolase activity
AUT26_06420	COG2873	o-acetylhomoserine
AUT26_06425	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AUT26_06465	COG0423	glycine-tRNA ligase activity
AUT26_06490	COG0358	DNA primase activity
AUT26_06510	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AUT26_06515	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AUT26_06545	COG0297	glycogen (starch) synthase activity
AUT26_06555	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
AUT26_06570	COG0052	Belongs to the universal ribosomal protein uS2 family
AUT26_06575	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AUT26_06580	COG0528	UMP kinase activity
AUT26_06585	COG0233	cytoplasmic translational termination
AUT26_06590	COG0575	Belongs to the CDS family
AUT26_06605	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AUT26_06620	COG3275	phosphorelay sensor kinase activity
AUT26_06630	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AUT26_06635	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AUT26_06635	COG1796	DNA polymerase
AUT26_06645	COG1522	sequence-specific DNA binding
AUT26_06655	COG0022	dehydrogenase e1 component
AUT26_06660	COG0508	dehydrogenase complex catalyzes the overall conversion of
AUT26_06665	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AUT26_06675	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AUT26_06685	COG1960	acyl-CoA dehydrogenase activity
AUT26_06725	COG0673	inositol 2-dehydrogenase activity
AUT26_06735	COG1175	transmembrane transport
AUT26_06740	COG1653	transport
AUT26_06755	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AUT26_06760	COG0750	zinc metalloprotease
AUT26_06770	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AUT26_06795	COG0442	prolyl-tRNA aminoacylation
AUT26_06815	COG0779	Required for maturation of 30S ribosomal subunits
AUT26_06830	COG0481	GTPase activity
AUT26_06830	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AUT26_06835	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AUT26_06840	COG0590	tRNA wobble adenosine to inosine editing
AUT26_06850	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AUT26_06870	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AUT26_06875	COG1185	polyribonucleotide nucleotidyltransferase activity
AUT26_06880	COG0612	Peptidase, M16
AUT26_06900	COG0745	RESPONSE REGULATOR receiver
AUT26_06905	COG2205	protein histidine kinase activity
AUT26_06925	COG0521	Mo-molybdopterin cofactor biosynthetic process
AUT26_06935	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AUT26_06955	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AUT26_06960	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AUT26_06965	COG1674	ftsk spoiiie
AUT26_06975	COG1546	Belongs to the CinA family
AUT26_06975	COG1058	Belongs to the CinA family
AUT26_06980	COG1396	sequence-specific DNA binding
AUT26_06995	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AUT26_07000	COG2137	regulation of response to DNA damage stimulus
AUT26_07005	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AUT26_07010	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AUT26_07015	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AUT26_07020	COG2813	Specifically methylates the guanine in position
AUT26_07025	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AUT26_07035	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AUT26_07040	COG1388	LysM domain
AUT26_07045	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AUT26_07050	COG0131	Imidazoleglycerol-phosphate dehydratase
AUT26_07055	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AUT26_07060	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AUT26_07080	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AUT26_07085	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AUT26_07090	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AUT26_07095	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AUT26_07100	COG2814	Major facilitator Superfamily
AUT26_07105	COG2816	NAD+ diphosphatase activity
AUT26_07115	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
AUT26_07130	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AUT26_07135	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AUT26_07135	COG0072	phenylalanine-tRNA ligase activity
AUT26_07150	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AUT26_07155	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AUT26_07160	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AUT26_07165	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AUT26_07170	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AUT26_07175	COG1438	arginine binding
AUT26_07180	COG0137	argininosuccinate synthase activity
AUT26_07185	COG0165	Argininosuccinate lyase
AUT26_07200	COG2094	Belongs to the DNA glycosylase MPG family
AUT26_07210	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AUT26_07235	COG0647	UMP catabolic process
AUT26_07250	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AUT26_07255	COG0497	DNA recombination
AUT26_07260	COG0504	CTP synthase activity
AUT26_07290	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AUT26_07295	COG2079	MmgE PrpD family protein
AUT26_07310	COG3290	protein histidine kinase activity
AUT26_07315	COG1301	dicarboxylic acid transport
AUT26_07325	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AUT26_07330	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AUT26_07345	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AUT26_07355	COG1160	GTP binding
AUT26_07370	COG2814	Major facilitator Superfamily
AUT26_07375	COG0509	glycine decarboxylation via glycine cleavage system
AUT26_07380	COG1716	ATPase activity
AUT26_07405	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AUT26_07415	COG1940	carbohydrate kinase activity
AUT26_07440	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
AUT26_07445	COG2815	serine threonine protein kinase
AUT26_07445	COG0515	serine threonine protein kinase
AUT26_07450	COG1388	LysM domain
AUT26_07450	COG3942	CHAP domain
AUT26_07460	COG0142	geranyltranstransferase activity
AUT26_07480	COG2001	Belongs to the MraZ family
AUT26_07485	COG0275	rRNA processing
AUT26_07495	COG0768	penicillin binding
AUT26_07500	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AUT26_07510	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AUT26_07515	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AUT26_07525	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AUT26_07530	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AUT26_07540	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AUT26_07550	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AUT26_07555	COG1799	cell septum assembly
AUT26_07570	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AUT26_07580	COG0587	DNA-directed DNA polymerase activity
AUT26_07595	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AUT26_07600	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AUT26_07615	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AUT26_07620	COG0174	glutamine synthetase
AUT26_07625	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AUT26_07655	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AUT26_07660	COG0321	lipoyl(octanoyl) transferase activity
AUT26_07670	COG1090	epimerase
AUT26_07675	COG4946	Tricorn protease homolog
AUT26_07675	COG0793	Belongs to the peptidase S41A family
AUT26_07680	COG1764	response to oxidative stress
AUT26_07690	COG0508	dehydrogenase complex catalyzes the overall conversion of
AUT26_07695	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AUT26_07700	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AUT26_07720	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AUT26_07745	COG1271	oxidase subunit
AUT26_07750	COG1294	oxidase, subunit
AUT26_07755	COG4988	ABC transporter
AUT26_07775	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AUT26_07780	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AUT26_07780	COG1042	CoA-binding domain protein
AUT26_07780	COG0045	succinate-CoA ligase (ADP-forming) activity
AUT26_07795	COG1435	thymidine kinase activity
AUT26_07815	COG0756	dUTP diphosphatase activity
AUT26_07840	COG0569	domain protein
AUT26_07845	COG0531	amino acid
AUT26_07850	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AUT26_07855	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AUT26_07860	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AUT26_07880	COG0667	Aldo Keto reductase
AUT26_07885	COG1024	Enoyl-CoA hydratase
AUT26_07885	COG1250	3-hydroxyacyl-CoA dehydrogenase
AUT26_07890	COG0183	Belongs to the thiolase family
AUT26_07915	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AUT26_07930	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AUT26_07950	COG3135	benzoate transporter
AUT26_07960	COG0531	amino acid
AUT26_08010	COG0242	peptide deformylase activity
AUT26_08015	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AUT26_08025	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AUT26_08050	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AUT26_08055	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AUT26_08060	COG0140	phosphoribosyl-ATP diphosphatase activity
AUT26_08065	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AUT26_08070	COG0107	imidazoleglycerol-phosphate synthase activity
AUT26_08080	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AUT26_08100	COG0134	indole-3-glycerol-phosphate synthase activity
AUT26_08105	COG0133	tryptophan synthase activity
AUT26_08110	COG0159	tryptophan synthase activity
AUT26_08115	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AUT26_08120	COG0070	glutamate synthase
AUT26_08120	COG0069	glutamate synthase activity
AUT26_08120	COG0067	glutamate synthase
AUT26_08145	COG0582	viral genome integration into host DNA
AUT26_08275	COG0667	Aldo Keto reductase
AUT26_08310	COG0789	Transcriptional regulator
AUT26_08365	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AUT26_08380	COG2188	Transcriptional regulator
AUT26_08395	COG4221	oxidoreductase activity
AUT26_08400	COG0583	DNA-binding transcription factor activity
AUT26_08405	COG1012	belongs to the aldehyde dehydrogenase family
AUT26_08410	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AUT26_08425	COG0596	Alpha beta hydrolase
AUT26_08440	COG2826	transposase and inactivated derivatives, IS30 family
AUT26_08455	COG1879	ABC-type sugar transport system periplasmic component
AUT26_08460	COG1053	succinate dehydrogenase
AUT26_08465	COG1454	alcohol dehydrogenase
AUT26_08475	COG1172	Belongs to the binding-protein-dependent transport system permease family
AUT26_08480	COG1172	Belongs to the binding-protein-dependent transport system permease family
AUT26_08485	COG1129	ABC transporter
AUT26_08520	COG1028	Short-chain dehydrogenase reductase Sdr
AUT26_08525	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AUT26_08550	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AUT26_08565	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AUT26_08585	COG1126	abc transporter atp-binding protein
AUT26_08595	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AUT26_08600	COG2188	Transcriptional regulator
AUT26_08605	COG3328	transposase activity
AUT26_08610	COG3328	transposase activity
AUT26_08655	COG0745	RESPONSE REGULATOR receiver
AUT26_08675	COG0598	Magnesium transport protein CorA
AUT26_08735	COG0800	Aldolase
AUT26_08745	COG1609	Transcriptional regulator
AUT26_08785	COG0395	ABC-type sugar transport system, permease component
AUT26_08815	COG3654	unkown
AUT26_08830	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AUT26_08840	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
AUT26_08850	COG0583	DNA-binding transcription factor activity
AUT26_08895	COG0318	PFAM AMP-dependent synthetase and ligase
AUT26_08940	COG0179	Fumarylacetoacetate (FAA) hydrolase
AUT26_08950	COG0148	phosphopyruvate hydratase activity
AUT26_08955	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AUT26_08960	COG0179	Fumarylacetoacetate (FAA) hydrolase
AUT26_08985	COG1609	Transcriptional regulator
AUT26_08990	COG2814	Major facilitator Superfamily
AUT26_09010	COG0183	Belongs to the thiolase family
AUT26_09015	COG2902	Dehydrogenase
AUT26_09025	COG3654	unkown
AUT26_09045	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AUT26_09065	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AUT26_09075	COG0395	ABC-type sugar transport system, permease component
AUT26_09090	COG3976	FMN-binding domain protein
AUT26_09090	COG1053	succinate dehydrogenase
AUT26_09115	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AUT26_09125	COG0583	DNA-binding transcription factor activity
AUT26_09185	COG2217	Heavy metal translocating P-type atpase
AUT26_09190	COG2132	Multicopper oxidase
AUT26_09200	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AUT26_09225	COG1175	transmembrane transport
AUT26_09235	COG3684	Belongs to the aldolase LacD family
AUT26_09245	COG0673	inositol 2-dehydrogenase activity
AUT26_09250	COG1349	DNA-binding transcription factor activity
AUT26_09260	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AUT26_09270	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AUT26_09290	COG3415	Transposase
AUT26_09290	COG2801	Transposase and inactivated derivatives
AUT26_09295	COG1609	Transcriptional regulator
AUT26_09310	COG1172	Belongs to the binding-protein-dependent transport system permease family
AUT26_09315	COG1129	ABC transporter
AUT26_09350	COG1131	(ABC) transporter
AUT26_09370	COG0726	polysaccharide deacetylase
AUT26_09385	COG1131	(ABC) transporter
AUT26_09405	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AUT26_09405	COG0574	Belongs to the PEP-utilizing enzyme family
AUT26_09420	COG1937	Protein conserved in bacteria
AUT26_09470	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AUT26_09480	COG0508	dehydrogenase complex catalyzes the overall conversion of
AUT26_09485	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AUT26_09500	COG3415	Transposase
AUT26_09500	COG2801	Transposase and inactivated derivatives
AUT26_09520	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AUT26_09565	COG0857	belongs to the CobB CobQ family
AUT26_09565	COG0280	phosphate acetyltransferase
AUT26_09585	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AUT26_09590	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
AUT26_09620	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AUT26_09645	COG3962	Belongs to the TPP enzyme family
AUT26_09650	COG1012	belongs to the aldehyde dehydrogenase family
AUT26_09655	COG0673	inositol 2-dehydrogenase activity
AUT26_09660	COG1028	Short-chain dehydrogenase reductase Sdr
AUT26_09665	COG0129	dihydroxy-acid dehydratase activity
AUT26_09670	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AUT26_09680	COG0673	inositol 2-dehydrogenase activity
AUT26_09685	COG1129	ABC transporter
AUT26_09690	COG1172	Belongs to the binding-protein-dependent transport system permease family
AUT26_09725	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AUT26_09730	COG1228	amidohydrolase
AUT26_09740	COG3842	ATPase activity
AUT26_09760	COG0477	Major facilitator Superfamily
AUT26_09765	COG2175	clavaminate synthase activity
AUT26_09775	COG2080	2 iron, 2 sulfur cluster binding
AUT26_09790	COG1012	belongs to the aldehyde dehydrogenase family
AUT26_09815	COG1028	Short-chain dehydrogenase reductase Sdr
AUT26_09850	COG1846	Transcriptional regulator
AUT26_09855	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
AUT26_09860	COG2197	response regulator
AUT26_09910	COG0572	uridine kinase
AUT26_09930	COG0251	oxidation-reduction process
AUT26_09935	COG0179	Fumarylacetoacetate (FAA) hydrolase
AUT26_09960	COG2814	Major facilitator Superfamily
AUT26_09995	COG3971	2-oxopent-4-enoate hydratase activity
AUT26_10010	COG1802	Transcriptional regulator
AUT26_10025	COG0028	Belongs to the TPP enzyme family
AUT26_10030	COG1793	dna ligase
AUT26_10030	COG3285	dna ligase
AUT26_10045	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AUT26_10070	COG0438	transferase activity, transferring glycosyl groups
AUT26_10080	COG0438	transferase activity, transferring glycosyl groups
AUT26_10085	COG0463	Glycosyl transferase, family 2
AUT26_10095	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AUT26_10110	COG1064	alcohol dehydrogenase
AUT26_10115	COG1643	Atp-dependent helicase
AUT26_10145	COG0009	L-threonylcarbamoyladenylate synthase
AUT26_10165	COG2971	BadF BadG BcrA BcrD
AUT26_10180	COG3483	tryptophan 2,3-dioxygenase activity
AUT26_10215	COG2050	protein possibly involved in aromatic compounds catabolism
AUT26_10225	COG4552	Acetyltransferase involved in intracellular survival and related
AUT26_10230	COG0539	negative regulation of cytoplasmic translation
AUT26_10235	COG1739	Uncharacterized protein family UPF0029
AUT26_10240	COG0237	dephospho-CoA kinase activity
AUT26_10240	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AUT26_10245	COG0556	nucleotide-excision repair
AUT26_10250	COG0861	Integral membrane protein TerC family
AUT26_10270	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AUT26_10280	COG4106	trans-aconitate 2-methyltransferase activity
AUT26_10295	COG0546	phosphoglycolate phosphatase activity
AUT26_10305	COG0322	excinuclease ABC activity
AUT26_10310	COG1660	Displays ATPase and GTPase activities
AUT26_10320	COG1481	regulation of sporulation
AUT26_10325	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AUT26_10330	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AUT26_10335	COG0126	phosphoglycerate kinase activity
AUT26_10340	COG0149	triose-phosphate isomerase activity
AUT26_10345	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AUT26_10350	COG0363	glucosamine-6-phosphate deaminase activity
AUT26_10365	COG0166	Belongs to the GPI family
AUT26_10370	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AUT26_10380	COG0109	protoheme IX farnesyltransferase activity
AUT26_10385	COG1612	heme a metabolic process
AUT26_10395	COG1131	(ABC) transporter
AUT26_10420	COG0396	ATPase activity
AUT26_10425	COG2151	metal-sulfur cluster biosynthetic enzyme
AUT26_10435	COG0318	PFAM AMP-dependent synthetase and ligase
AUT26_10450	COG1122	ATPase activity
AUT26_10455	COG1268	BioY protein
AUT26_10460	COG0488	(ABC) transporter
AUT26_10485	COG1028	Short-chain dehydrogenase reductase Sdr
AUT26_10490	COG1028	Short-chain dehydrogenase reductase Sdr
AUT26_10495	COG1129	ABC transporter
AUT26_10505	COG3830	Belongs to the UPF0237 family
AUT26_10505	COG0560	Phosphoserine phosphatase
AUT26_10510	COG1119	ATPase activity
AUT26_10525	COG0254	rRNA binding
AUT26_10550	COG1305	Transglutaminase-like
AUT26_10560	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AUT26_10565	COG0297	glycogen (starch) synthase activity
AUT26_10570	COG1960	acyl-CoA dehydrogenase activity
AUT26_10580	COG0183	Belongs to the thiolase family
AUT26_10585	COG1028	Short-chain dehydrogenase reductase Sdr
AUT26_10620	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AUT26_10625	COG0673	inositol 2-dehydrogenase activity
AUT26_10690	COG1088	dTDP-glucose 4,6-dehydratase activity
AUT26_10695	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AUT26_10700	COG0656	L-ascorbic acid biosynthetic process
AUT26_10705	COG1968	undecaprenyl-diphosphatase activity
AUT26_10710	COG0215	cysteine-tRNA ligase activity
AUT26_10720	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AUT26_10735	COG1222	aaa ATPase
AUT26_10740	COG4122	O-methyltransferase activity
AUT26_10750	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
AUT26_10755	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
AUT26_10760	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
AUT26_10765	COG0545	Peptidyl-prolyl cis-trans isomerase
AUT26_10785	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AUT26_10790	COG0805	protein transport
AUT26_10795	COG4581	dead DEAH box helicase
AUT26_10800	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AUT26_10805	COG1216	Glycosyl transferase, family 2
AUT26_10825	COG2226	methyltransferase
AUT26_10835	COG0242	peptide deformylase activity
AUT26_10850	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AUT26_10855	COG3424	synthase
AUT26_10865	COG0667	Aldo Keto reductase
AUT26_10900	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AUT26_10905	COG1845	cytochrome c oxidase, subunit III
AUT26_10910	COG2010	Cytochrome c
AUT26_10915	COG0723	plastoquinol--plastocyanin reductase activity
AUT26_10920	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AUT26_10925	COG2186	Transcriptional regulator
AUT26_10930	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AUT26_10940	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AUT26_10945	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AUT26_10965	COG0167	dihydroorotate dehydrogenase activity
AUT26_10980	COG2267	carboxylic ester hydrolase activity
AUT26_10985	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AUT26_10990	COG1381	Involved in DNA repair and RecF pathway recombination
AUT26_10995	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AUT26_11000	COG3590	peptidase
AUT26_11005	COG1316	TRANSCRIPTIONal
AUT26_11010	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AUT26_11020	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AUT26_11040	COG0484	heat shock protein binding
AUT26_11045	COG1420	regulation of RNA biosynthetic process
AUT26_11065	COG0481	GTPase activity
AUT26_11075	COG0268	Binds directly to 16S ribosomal RNA
AUT26_11095	COG1307	EDD domain protein, DegV family
AUT26_11100	COG0495	leucyl-tRNA aminoacylation
AUT26_11105	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AUT26_11110	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AUT26_11115	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AUT26_11120	COG2390	Transcriptional regulator
AUT26_11125	COG0656	L-ascorbic acid biosynthetic process
AUT26_11135	COG0438	transferase activity, transferring glycosyl groups
AUT26_11150	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AUT26_11160	COG1758	RNA polymerase activity
AUT26_11165	COG0194	GDP metabolic process
AUT26_11175	COG0284	orotidine-5'-phosphate decarboxylase activity
AUT26_11180	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AUT26_11185	COG0505	Belongs to the CarA family
AUT26_11195	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AUT26_11200	COG0540	Belongs to the ATCase OTCase family
AUT26_11205	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AUT26_11215	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AUT26_11220	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AUT26_11230	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AUT26_11235	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AUT26_11240	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AUT26_11245	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AUT26_11260	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AUT26_11275	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AUT26_11295	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AUT26_11300	COG0124	histidyl-tRNA synthetase
AUT26_11310	COG1196	nuclear chromosome segregation
AUT26_11320	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AUT26_11325	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AUT26_11330	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AUT26_11340	COG2255	four-way junction helicase activity
AUT26_11345	COG0632	four-way junction helicase activity
AUT26_11350	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AUT26_11355	COG0217	transcriptional regulatory protein
AUT26_11360	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
AUT26_11380	COG0339	signal peptide processing
AUT26_11385	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
AUT26_11400	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AUT26_11405	COG0587	DNA-directed DNA polymerase activity
AUT26_11430	COG2135	peptidase activity
AUT26_11445	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AUT26_11480	COG4804	nuclease activity
AUT26_11520	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AUT26_11530	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AUT26_11540	COG2963	transposase activity
AUT26_11565	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AUT26_11570	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AUT26_11575	COG1780	Probably involved in ribonucleotide reductase function
AUT26_11585	COG0583	DNA-binding transcription factor activity
AUT26_11625	COG0714	Associated with various cellular activities
AUT26_11635	COG1940	carbohydrate kinase activity
AUT26_11635	COG1846	Transcriptional regulator
AUT26_11640	COG2813	Specifically methylates the guanine in position
AUT26_11660	COG0799	negative regulation of ribosome biogenesis
AUT26_11670	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AUT26_11680	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AUT26_11685	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AUT26_11690	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AUT26_11695	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AUT26_11700	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AUT26_11705	COG0351	phosphomethylpyrimidine kinase
AUT26_11705	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AUT26_11705	COG0352	thiamine-phosphate diphosphorylase activity
AUT26_11710	COG1530	ribonuclease E activity
AUT26_11720	COG0105	UTP biosynthetic process
AUT26_11730	COG0285	dihydrofolate synthase activity
AUT26_11735	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AUT26_11755	COG0525	valine-tRNA ligase activity
AUT26_11760	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AUT26_11765	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AUT26_11770	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AUT26_11775	COG0740	serine-type endopeptidase activity
AUT26_11780	COG0740	serine-type endopeptidase activity
AUT26_11785	COG0544	peptidyl-prolyl cis-trans isomerase activity
AUT26_11830	COG0668	transmembrane transport
AUT26_11845	COG1946	Acyl-CoA thioesterase
AUT26_11890	COG0242	peptide deformylase activity
AUT26_11920	COG3022	response to hydroperoxide
AUT26_11930	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AUT26_11935	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AUT26_11945	COG1045	serine acetyltransferase
AUT26_11950	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AUT26_11960	COG1063	alcohol dehydrogenase
AUT26_11965	COG1028	Short-chain dehydrogenase reductase Sdr
AUT26_11970	COG2084	Dehydrogenase
AUT26_11980	COG0477	Major facilitator Superfamily
AUT26_12015	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AUT26_12030	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AUT26_12035	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AUT26_12050	COG4974	Belongs to the 'phage' integrase family
AUT26_12060	COG0606	chelatase, subunit chli
AUT26_12065	COG0792	nuclease activity
AUT26_12075	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AUT26_12085	COG0681	Belongs to the peptidase S26 family
AUT26_12090	COG0335	large ribosomal subunit rRNA binding
AUT26_12095	COG0336	Belongs to the RNA methyltransferase TrmD family
AUT26_12100	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AUT26_12105	COG1837	Belongs to the UPF0109 family
AUT26_12110	COG0228	four-way junction DNA binding
AUT26_12120	COG2514	catechol 2,3-dioxygenase activity
AUT26_12145	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AUT26_12160	COG2814	Major facilitator Superfamily
AUT26_12200	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AUT26_12205	COG0571	ribonuclease III activity
AUT26_12210	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AUT26_12225	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AUT26_12240	COG0742	ribosomal rna small subunit methyltransferase
AUT26_12250	COG1461	Dihydroxyacetone kinase
AUT26_12265	COG1181	Belongs to the D-alanine--D-alanine ligase family
AUT26_12270	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AUT26_12280	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AUT26_12285	COG0066	3-isopropylmalate dehydratase activity
AUT26_12290	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AUT26_12295	COG1414	Transcriptional regulator
AUT26_12330	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AUT26_12340	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AUT26_12345	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AUT26_12350	COG0473	3-isopropylmalate dehydrogenase activity
AUT26_12355	COG4585	Histidine kinase
AUT26_12360	COG2197	response regulator
AUT26_12365	COG0577	efflux transmembrane transporter activity
AUT26_12365	COG1136	(ABC) transporter
AUT26_12380	COG1136	(ABC) transporter
AUT26_12380	COG0577	efflux transmembrane transporter activity
AUT26_12390	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AUT26_12395	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AUT26_12400	COG0440	acetolactate synthase activity
AUT26_12410	COG0129	dihydroxy-acid dehydratase activity
AUT26_12420	COG2133	pyrroloquinoline quinone binding
AUT26_12450	COG0747	negative chemotaxis
AUT26_12455	COG0579	oxidoreductase
AUT26_12460	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AUT26_12465	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AUT26_12470	COG1846	Transcriptional regulator
AUT26_12475	COG1305	Transglutaminase-like
AUT26_12485	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AUT26_12500	COG1104	cysteine desulfurase activity
AUT26_12510	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AUT26_12515	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AUT26_12525	COG1522	sequence-specific DNA binding
AUT26_12530	COG1113	amino acid transport
AUT26_12540	COG0022	dehydrogenase e1 component
AUT26_12545	COG0508	dehydrogenase complex catalyzes the overall conversion of
AUT26_12565	COG0477	Major facilitator Superfamily
AUT26_12570	COG1414	Transcriptional regulator
AUT26_12580	COG0419	ATPase involved in DNA repair
AUT26_12585	COG0420	3'-5' exonuclease activity
AUT26_12600	COG2149	membrane
AUT26_12625	COG1131	(ABC) transporter
AUT26_12640	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AUT26_12645	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AUT26_12650	COG1234	tRNA 3'-trailer cleavage
AUT26_12655	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AUT26_12665	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AUT26_12675	COG1335	isochorismatase
AUT26_12690	COG0363	glucosamine-6-phosphate deaminase activity
AUT26_12705	COG1902	pentaerythritol trinitrate reductase activity
AUT26_12735	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
AUT26_12740	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AUT26_12750	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AUT26_12755	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AUT26_12765	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AUT26_12770	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AUT26_12775	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AUT26_12780	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AUT26_12785	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AUT26_12790	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AUT26_12795	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AUT26_12800	COG0356	it plays a direct role in the translocation of protons across the membrane
AUT26_12815	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AUT26_12835	COG2890	protein-(glutamine-N5) methyltransferase activity
AUT26_12840	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AUT26_12850	COG0083	homoserine kinase activity
AUT26_12855	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AUT26_12860	COG0460	homoserine dehydrogenase
AUT26_12865	COG0019	diaminopimelate decarboxylase activity
AUT26_12870	COG0018	arginyl-trna synthetase
AUT26_12885	COG1017	nitric oxide dioxygenase activity
AUT26_12885	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AUT26_12915	COG1643	Atp-dependent helicase
AUT26_12920	COG0537	adenosine 5'-monophosphoramidase activity
AUT26_12925	COG1064	alcohol dehydrogenase
AUT26_12950	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AUT26_12955	COG1121	(ABC) transporter
AUT26_12960	COG0803	Belongs to the bacterial solute-binding protein 9 family
AUT26_12970	COG1253	flavin adenine dinucleotide binding
AUT26_12975	COG0567	Dehydrogenase, E1 component
AUT26_12975	COG0508	dehydrogenase complex catalyzes the overall conversion of
AUT26_13000	COG1595	DNA-templated transcription, initiation
AUT26_13010	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AUT26_13020	COG0483	inositol monophosphate 1-phosphatase activity
AUT26_13025	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AUT26_13060	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AUT26_13065	COG0739	heme binding
AUT26_13070	COG2177	Part of the ABC transporter FtsEX involved in
AUT26_13075	COG2884	Cell division ATP-binding protein ftsE
AUT26_13080	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AUT26_13170	COG1216	Glycosyl transferase, family 2
AUT26_13185	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AUT26_13215	COG2902	Dehydrogenase
AUT26_13250	COG0653	protein targeting
AUT26_13255	COG3214	Protein conserved in bacteria
AUT26_13260	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AUT26_13270	COG5401	PFAM Sporulation and spore germination
AUT26_13280	COG0745	RESPONSE REGULATOR receiver
AUT26_13330	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AUT26_13335	COG0601	transmembrane transport
AUT26_13355	COG0482	sulfurtransferase activity
AUT26_13385	COG0484	heat shock protein binding
AUT26_13390	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AUT26_13395	COG1595	DNA-templated transcription, initiation
AUT26_13405	COG3265	gluconokinase activity
AUT26_13415	COG2801	Transposase and inactivated derivatives
AUT26_13415	COG3415	Transposase
AUT26_13425	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AUT26_13430	COG2086	electron transfer activity
AUT26_13435	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AUT26_13445	COG1842	Phage shock protein A
AUT26_13465	COG1615	UPF0182 protein
AUT26_13470	COG3480	Lon protease (S16) C-terminal proteolytic domain
AUT26_13490	COG2816	NAD+ diphosphatase activity
AUT26_13505	COG1074	ATP-dependent DNA helicase activity
AUT26_13520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AUT26_13525	COG0765	amino acid transport
AUT26_13535	COG1472	Belongs to the glycosyl hydrolase 3 family
AUT26_13545	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AUT26_13555	COG0113	porphobilinogen synthase activity
AUT26_13565	COG0181	hydroxymethylbilane synthase activity
AUT26_13585	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AUT26_13590	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AUT26_13600	COG1309	transcriptional regulator
AUT26_13630	COG0352	thiamine-phosphate diphosphorylase activity
AUT26_13645	COG0513	Belongs to the DEAD box helicase family
AUT26_13655	COG2095	MarC family integral membrane protein
AUT26_13660	COG0613	PHP domain protein
AUT26_13665	COG0006	proline dipeptidase activity
AUT26_13675	COG2239	Acts as a magnesium transporter
AUT26_13690	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AUT26_13700	COG1595	DNA-templated transcription, initiation
AUT26_13705	COG4122	O-methyltransferase activity
AUT26_13730	COG1126	abc transporter atp-binding protein
AUT26_13735	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AUT26_13740	COG0765	amino acid transport
AUT26_13745	COG0765	amino acid transport
AUT26_13750	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AUT26_13755	COG2171	N-acyltransferase activity
AUT26_13770	COG3415	Transposase
AUT26_13770	COG2801	Transposase and inactivated derivatives
AUT26_13780	COG3226	Transcriptional regulator
AUT26_13785	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AUT26_13830	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AUT26_13835	COG0601	transmembrane transport
AUT26_13840	COG0747	negative chemotaxis
AUT26_13855	COG0012	GTP binding
AUT26_13860	COG1322	Protein conserved in bacteria
AUT26_13865	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AUT26_13875	COG1570	exodeoxyribonuclease VII activity
AUT26_13880	COG1722	exodeoxyribonuclease VII activity
AUT26_13885	COG2326	polyphosphate kinase activity
AUT26_13905	COG1174	glycine betaine transport
AUT26_13915	COG1162	GTPase activity
AUT26_13930	COG2971	BadF BadG BcrA BcrD
AUT26_13940	COG2814	Major facilitator Superfamily
AUT26_13945	COG3548	integral membrane protein
AUT26_13965	COG0598	Magnesium transport protein CorA
AUT26_13970	COG1528	Iron-storage protein
AUT26_13975	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AUT26_13980	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AUT26_13990	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AUT26_13995	COG1695	Transcriptional regulator
AUT26_14025	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AUT26_14030	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AUT26_14050	COG0519	Catalyzes the synthesis of GMP from XMP
AUT26_14050	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AUT26_14070	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AUT26_14090	COG0516	GMP reductase activity
AUT26_14095	COG1132	(ABC) transporter
AUT26_14115	COG0459	protein refolding
AUT26_14120	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AUT26_14135	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AUT26_14140	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AUT26_14150	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AUT26_14155	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AUT26_14170	COG0802	atpase or kinase
AUT26_14175	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AUT26_14185	COG1486	melibiose metabolic process
AUT26_14195	COG0438	transferase activity, transferring glycosyl groups
AUT26_14200	COG2759	Belongs to the formate--tetrahydrofolate ligase family
AUT26_14210	COG0667	Aldo Keto reductase
AUT26_14235	COG0736	holo-[acyl-carrier-protein] synthase activity
AUT26_14245	COG1072	(Pantothenic acid kinase))
AUT26_14250	COG1876	peptidase activity
AUT26_14255	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AUT26_14260	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AUT26_14265	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AUT26_14295	COG0455	bacterial-type flagellum organization
AUT26_14315	COG0101	tRNA pseudouridine synthase activity
AUT26_14320	COG0203	ribosomal protein L17
AUT26_14325	COG0202	RNA polymerase activity
AUT26_14330	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AUT26_14335	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AUT26_14340	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AUT26_14345	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AUT26_14350	COG3191	aminopeptidase activity
AUT26_14370	COG0024	Methionine aminopeptidase
AUT26_14380	COG0318	PFAM AMP-dependent synthetase and ligase
AUT26_14390	COG1442	glycosyl transferase family 8
AUT26_14390	COG1216	Glycosyl transferase, family 2
AUT26_14395	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AUT26_14400	COG0563	adenylate kinase activity
AUT26_14410	COG0200	Binds to the 23S rRNA
AUT26_14415	COG1841	ribosomal large subunit assembly
AUT26_14420	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AUT26_14430	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AUT26_14435	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AUT26_14440	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AUT26_14445	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AUT26_14450	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AUT26_14455	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AUT26_14460	COG0255	Belongs to the universal ribosomal protein uL29 family
AUT26_14465	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AUT26_14470	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AUT26_14475	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AUT26_14480	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AUT26_14485	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AUT26_14490	COG0089	rRNA binding
AUT26_14495	COG0088	Forms part of the polypeptide exit tunnel
AUT26_14500	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AUT26_14505	COG0051	transcription antitermination factor activity, RNA binding
AUT26_14520	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AUT26_14525	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AUT26_14530	COG0049	tRNA binding
AUT26_14535	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AUT26_14540	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AUT26_14545	COG0085	RNA polymerase activity
AUT26_14550	COG0183	Belongs to the thiolase family
AUT26_14555	COG0442	prolyl-tRNA aminoacylation
AUT26_14560	COG0222	ribosome binding
AUT26_14565	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AUT26_14580	COG0081	regulation of translation
AUT26_14585	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AUT26_14595	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AUT26_14605	COG0436	Aminotransferase
AUT26_14610	COG2197	response regulator
AUT26_14660	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AUT26_14670	COG3485	protocatechuate 3,4-dioxygenase
AUT26_14680	COG0745	RESPONSE REGULATOR receiver
AUT26_14685	COG0456	acetyltransferase
AUT26_14690	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AUT26_14705	COG1725	Transcriptional regulator
AUT26_14710	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AUT26_14715	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AUT26_14725	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AUT26_14740	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AUT26_14750	COG2030	dehydratase
AUT26_14775	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AUT26_14785	COG4989	oxidoreductase activity
AUT26_14790	COG0366	Alpha amylase catalytic
AUT26_14810	COG1940	carbohydrate kinase activity
AUT26_14820	COG0702	epimerase
AUT26_14855	COG0754	glutathionylspermidine amidase activity
AUT26_14880	COG0395	ABC-type sugar transport system, permease component
AUT26_14895	COG1733	regulation of RNA biosynthetic process
AUT26_14900	COG1051	belongs to the nudix hydrolase family
AUT26_14925	COG3415	Transposase
AUT26_14925	COG2801	Transposase and inactivated derivatives
AUT26_14940	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AUT26_14955	COG1131	(ABC) transporter
AUT26_14975	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AUT26_14990	COG1666	GTP binding
AUT26_14995	COG0501	Belongs to the peptidase M48B family
AUT26_15025	COG0531	amino acid
AUT26_15060	COG1012	belongs to the aldehyde dehydrogenase family
AUT26_15065	COG3835	regulator
AUT26_15070	COG2807	transmembrane transport
AUT26_15075	COG2186	Transcriptional regulator
AUT26_15080	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AUT26_15080	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AUT26_15090	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AUT26_15090	COG1648	precorrin-2 dehydrogenase activity
AUT26_15095	COG2066	Belongs to the glutaminase family
AUT26_15100	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AUT26_15110	COG1733	regulation of RNA biosynthetic process
AUT26_15125	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AUT26_15130	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AUT26_15130	COG1116	anion transmembrane transporter activity
AUT26_15140	COG2040	homocysteine
AUT26_15145	COG2895	sulfate adenylyltransferase (ATP) activity
AUT26_15155	COG0175	sulfate reduction
AUT26_15160	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AUT26_15170	COG2860	membrane
AUT26_15195	COG0644	oxidoreductase
AUT26_15200	COG2226	methyltransferase
AUT26_15205	COG1169	isochorismate synthase
AUT26_15210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AUT26_15215	COG0765	amino acid transport
AUT26_15225	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
AUT26_15235	COG4948	Mandelate Racemase Muconate Lactonizing
AUT26_15250	COG1609	Transcriptional regulator
AUT26_15255	COG1621	beta-fructofuranosidase activity
AUT26_15260	COG0395	ABC-type sugar transport system, permease component
AUT26_15265	COG1175	transmembrane transport
AUT26_15325	COG1404	Belongs to the peptidase S8 family
AUT26_15330	COG0508	dehydrogenase complex catalyzes the overall conversion of
AUT26_15335	COG0022	dehydrogenase e1 component
AUT26_15365	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AUT26_15400	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AUT26_15410	COG1134	teichoic acid transport
AUT26_15440	COG1316	TRANSCRIPTIONal
AUT26_15450	COG1597	lipid kinase activity
AUT26_15455	COG1024	Enoyl-CoA hydratase
AUT26_15460	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AUT26_15465	COG2151	metal-sulfur cluster biosynthetic enzyme
AUT26_15470	COG3396	Phenylacetate-CoA oxygenase
AUT26_15475	COG3460	Phenylacetate-CoA oxygenase
AUT26_15480	COG3396	Phenylacetate-CoA oxygenase
AUT26_15485	COG0463	Glycosyl transferase, family 2
AUT26_15500	COG4251	negative regulation of phosphorylation
AUT26_15500	COG5001	Diguanylate cyclase
AUT26_15500	COG3706	GGDEF domain
AUT26_15500	COG2203	Gaf domain
AUT26_15520	COG5002	protein histidine kinase activity
AUT26_15535	COG2801	Transposase and inactivated derivatives
AUT26_15535	COG3415	Transposase
AUT26_15545	COG2050	protein possibly involved in aromatic compounds catabolism
AUT26_15565	COG1012	belongs to the aldehyde dehydrogenase family
AUT26_15565	COG2030	dehydratase
AUT26_15570	COG1216	Glycosyl transferase, family 2
AUT26_15585	COG1250	3-hydroxyacyl-CoA dehydrogenase
AUT26_15590	COG1024	Enoyl-CoA hydratase
AUT26_15595	COG0183	Belongs to the thiolase family
AUT26_15620	COG0488	(ABC) transporter
AUT26_15625	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AUT26_15630	COG1121	(ABC) transporter
AUT26_15635	COG0803	Belongs to the bacterial solute-binding protein 9 family
AUT26_15640	COG1266	CAAX protease self-immunity
AUT26_15655	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AUT26_15705	COG0443	Heat shock 70 kDa protein
AUT26_15710	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AUT26_15720	COG0785	Cytochrome C biogenesis protein
AUT26_15730	COG0406	alpha-ribazole phosphatase activity
AUT26_15750	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
AUT26_15760	COG0560	Phosphoserine phosphatase
AUT26_15775	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AUT26_15780	COG3458	cephalosporin-C deacetylase activity
AUT26_15790	COG2755	lipolytic protein G-D-S-L family
AUT26_15795	COG0395	ABC-type sugar transport system, permease component
AUT26_15800	COG4209	transmembrane transport
AUT26_15805	COG1653	transport
AUT26_15820	COG0673	inositol 2-dehydrogenase activity
AUT26_15825	COG2814	Major facilitator Superfamily
AUT26_15835	COG0395	ABC-type sugar transport system, permease component
AUT26_15840	COG1175	transmembrane transport
AUT26_15860	COG0395	ABC-type sugar transport system, permease component
AUT26_15865	COG1175	transmembrane transport
AUT26_15890	COG4948	Mandelate Racemase Muconate Lactonizing
AUT26_15895	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AUT26_15905	COG0673	inositol 2-dehydrogenase activity
AUT26_15910	COG1609	Transcriptional regulator
AUT26_15925	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AUT26_15930	COG0640	Transcriptional regulator
AUT26_15940	COG0123	including yeast histone deacetylase and acetoin utilization protein
AUT26_15945	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AUT26_15950	COG0569	domain protein
AUT26_15955	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AUT26_15965	COG1082	Xylose isomerase domain protein TIM barrel
AUT26_15980	COG1754	DNA topoisomerase type I activity
AUT26_15980	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AUT26_15990	COG2890	protein-(glutamine-N5) methyltransferase activity
AUT26_16015	COG1205	dead DEAH box helicase
AUT26_16015	COG1111	helicase
AUT26_16085	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AUT26_16090	COG1349	DNA-binding transcription factor activity
AUT26_16095	COG1609	Transcriptional regulator
AUT26_16105	COG4209	transmembrane transport
AUT26_16110	COG0395	ABC-type sugar transport system, permease component
AUT26_16125	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AUT26_16150	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AUT26_16155	COG1408	metallophosphoesterase
AUT26_16160	COG1132	(ABC) transporter
AUT26_16165	COG1132	(ABC) transporter
AUT26_16185	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AUT26_16190	COG0151	Belongs to the GarS family
AUT26_16205	COG1301	dicarboxylic acid transport
AUT26_16210	COG1028	Short-chain dehydrogenase reductase Sdr
AUT26_16220	COG1953	Uracil, thiamine, allantoin
AUT26_16225	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AUT26_16240	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AUT26_16250	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AUT26_16250	COG3608	succinylglutamate desuccinylase aspartoacylase
AUT26_16255	COG2252	PERMEase
AUT26_16260	COG0590	tRNA wobble adenosine to inosine editing
AUT26_16285	COG2233	PERMEase
AUT26_16290	COG1414	Transcriptional regulator
AUT26_16310	COG3257	ureidoglycine aminohydrolase activity
AUT26_16325	COG2318	DinB family
AUT26_16330	COG4585	Histidine kinase
AUT26_16335	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AUT26_16360	COG0659	secondary active sulfate transmembrane transporter activity
AUT26_16390	COG0563	adenylate kinase activity
AUT26_16405	COG0300	oxidoreductase activity
AUT26_16420	COG1569	PIN domain
AUT26_16425	COG3311	Transcriptional regulator
AUT26_16450	COG2267	carboxylic ester hydrolase activity
AUT26_16515	COG0405	Gamma-glutamyltransferase
AUT26_16555	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AUT26_16570	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AUT26_16575	COG0673	inositol 2-dehydrogenase activity
AUT26_16585	COG0673	inositol 2-dehydrogenase activity
AUT26_16600	COG1653	transport
AUT26_16605	COG1609	Transcriptional regulator
AUT26_16665	COG2801	Transposase and inactivated derivatives
AUT26_16675	COG3622	Belongs to the hyi family
AUT26_16680	COG2084	Dehydrogenase
AUT26_16685	COG3960	tartronate-semialdehyde synthase activity
AUT26_16690	COG1929	Belongs to the glycerate kinase type-1 family
AUT26_16695	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AUT26_16720	COG1366	Belongs to the anti-sigma-factor antagonist family
AUT26_16745	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AUT26_16750	COG0671	phosphoesterase, PA-phosphatase related
AUT26_16775	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AUT26_16810	COG0542	response to heat
AUT26_16835	COG3585	molybdate ion transport
AUT26_16855	COG3304	Inner membrane component domain
AUT26_16865	COG0135	phosphoribosylanthranilate isomerase activity
AUT26_16875	COG2076	Multidrug Resistance protein
AUT26_16880	COG2076	Multidrug Resistance protein
AUT26_16905	COG2813	Specifically methylates the guanine in position
AUT26_16920	COG0477	Major facilitator Superfamily
AUT26_16925	COG2807	transmembrane transport
AUT26_16930	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AUT26_16965	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AUT26_16980	COG3177	Filamentation induced by cAMP protein fic
AUT26_17030	COG3959	Transketolase, thiamine diphosphate binding domain
AUT26_17035	COG3958	Transketolase
AUT26_17040	COG1105	Belongs to the carbohydrate kinase PfkB family
AUT26_17055	COG0477	Major facilitator Superfamily
AUT26_17060	COG4221	oxidoreductase activity
AUT26_17065	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AUT26_17090	COG0800	Aldolase
AUT26_17100	COG1063	alcohol dehydrogenase
AUT26_17105	COG1063	alcohol dehydrogenase
AUT26_17110	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AUT26_17120	COG2140	Oxalate decarboxylase
AUT26_17125	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AUT26_17130	COG1737	Transcriptional regulator
AUT26_17140	COG1082	Xylose isomerase domain protein TIM barrel
AUT26_17145	COG1172	Belongs to the binding-protein-dependent transport system permease family
AUT26_17150	COG1129	ABC transporter
AUT26_17155	COG1879	ABC-type sugar transport system periplasmic component
AUT26_17160	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AUT26_17165	COG0789	Transcriptional regulator
AUT26_17170	COG0484	heat shock protein binding
AUT26_17175	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AUT26_17180	COG0443	Heat shock 70 kDa protein
AUT26_17185	COG3739	integral membrane protein
AUT26_17215	COG0477	Major facilitator Superfamily
AUT26_17225	COG3540	Alkaline phosphatase
AUT26_17285	COG0436	Aminotransferase
AUT26_17290	COG1064	alcohol dehydrogenase
AUT26_17310	COG1280	lysine exporter protein (LysE YggA)
AUT26_17320	COG2161	toxin-antitoxin pair type II binding
AUT26_17325	COG2026	Addiction module toxin, RelE StbE family
AUT26_17335	COG2409	Drug exporters of the RND superfamily
AUT26_17345	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AUT26_17350	COG3795	YCII-related domain
AUT26_17355	COG4941	Belongs to the sigma-70 factor family
AUT26_17360	COG0667	Aldo Keto reductase
AUT26_17375	COG1280	lysine exporter protein (LysE YggA)
AUT26_17380	COG1609	Transcriptional regulator
AUT26_17385	COG1957	nucleoside hydrolase
AUT26_17390	COG0477	Major facilitator Superfamily
AUT26_17395	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AUT26_17400	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AUT26_17410	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AUT26_17420	COG0833	amino acid
AUT26_17425	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AUT26_17435	COG2986	histidine ammonia-lyase
AUT26_17465	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AUT26_17470	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AUT26_17495	COG1122	ATPase activity
AUT26_17500	COG4721	ABC-type cobalt transport system, permease component
AUT26_17515	COG1320	monovalent cation:proton antiporter activity
AUT26_17520	COG2212	antiporter activity
AUT26_17540	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AUT26_17540	COG2111	Na H antiporter
AUT26_17555	COG0475	glutathione-regulated potassium exporter activity
AUT26_17565	COG0717	Belongs to the dCTP deaminase family
AUT26_17605	COG0583	DNA-binding transcription factor activity
AUT26_17615	COG1609	Transcriptional regulator
AUT26_17620	COG0673	inositol 2-dehydrogenase activity
AUT26_17645	COG2115	Belongs to the xylose isomerase family
AUT26_17650	COG1070	Carbohydrate kinase
AUT26_17655	COG1609	Transcriptional regulator
AUT26_17670	COG2160	L-arabinose isomerase activity
AUT26_17675	COG2017	converts alpha-aldose to the beta-anomer
AUT26_17680	COG1609	Transcriptional regulator
AUT26_17685	COG3254	rhamnose metabolic process
AUT26_17690	COG4952	isomerase
AUT26_17695	COG3347	Dehydrogenase
AUT26_17695	COG1028	Short-chain dehydrogenase reductase Sdr
AUT26_17700	COG1070	Carbohydrate kinase
AUT26_17715	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AUT26_17725	COG3387	PFAM Glycoside hydrolase 15-related
AUT26_17730	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AUT26_17750	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AUT26_17755	COG3118	belongs to the thioredoxin family
AUT26_17760	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AUT26_17775	COG1937	Protein conserved in bacteria
AUT26_17785	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AUT26_17810	COG1126	abc transporter atp-binding protein
AUT26_17830	COG0433	COG0433 Predicted ATPase
AUT26_17850	COG0776	regulation of translation
AUT26_17875	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AUT26_17880	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AUT26_17885	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AUT26_17910	COG1120	ATPase activity
AUT26_17915	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AUT26_17920	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AUT26_17960	COG3012	SEC-C Motif Domain Protein
AUT26_17975	COG0667	Aldo Keto reductase
AUT26_18030	COG2186	Transcriptional regulator
AUT26_18040	COG1027	Aspartate ammonia-lyase
AUT26_18050	COG2186	Transcriptional regulator
AUT26_18060	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AUT26_18065	COG4221	oxidoreductase activity
AUT26_18075	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AUT26_18085	COG1522	sequence-specific DNA binding
AUT26_18090	COG1280	lysine exporter protein (LysE YggA)
AUT26_18110	COG1414	Transcriptional regulator
AUT26_18120	COG0477	Major facilitator Superfamily
AUT26_18130	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AUT26_18155	COG1760	l-serine dehydratase
AUT26_18185	COG0281	malic enzyme
AUT26_18190	COG1309	transcriptional regulator
AUT26_18215	COG2211	Major facilitator Superfamily
AUT26_18220	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AUT26_18225	COG0477	Major facilitator Superfamily
AUT26_18230	COG0477	Major facilitator Superfamily
AUT26_18235	COG2814	Major facilitator Superfamily
AUT26_18240	COG1846	Transcriptional regulator
AUT26_18265	COG1113	amino acid transport
AUT26_18275	COG0246	Mannitol dehydrogenase
AUT26_18280	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AUT26_18280	COG2213	PTS system mannitol-specific
AUT26_18290	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AUT26_18310	COG2267	carboxylic ester hydrolase activity
AUT26_18320	COG1793	dna ligase
AUT26_18340	COG0686	Belongs to the AlaDH PNT family
AUT26_18370	COG0673	inositol 2-dehydrogenase activity
AUT26_18395	COG1309	transcriptional regulator
AUT26_18425	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AUT26_18470	COG0508	dehydrogenase complex catalyzes the overall conversion of
AUT26_18475	COG0022	dehydrogenase e1 component
AUT26_18485	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AUT26_18490	COG1950	PFAM Membrane protein of
AUT26_18505	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AUT26_18520	COG1607	acyl-coa hydrolase
AUT26_18525	COG4221	oxidoreductase activity
AUT26_18530	COG0477	Major facilitator Superfamily
AUT26_18535	COG1984	allophanate hydrolase subunit 2
AUT26_18540	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AUT26_18545	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AUT26_18550	COG0583	DNA-binding transcription factor activity
AUT26_18560	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AUT26_18595	COG2261	transglycosylase associated protein
AUT26_18605	COG3708	Transcriptional regulator
AUT26_18605	COG2207	Transcriptional regulator
AUT26_18615	COG1028	Short-chain dehydrogenase reductase Sdr
AUT26_18630	COG1621	beta-fructofuranosidase activity
AUT26_18645	COG1653	transport
AUT26_18655	COG0395	ABC-type sugar transport system, permease component
AUT26_18665	COG1621	beta-fructofuranosidase activity
AUT26_18670	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AUT26_18685	COG0515	serine threonine protein kinase
AUT26_18685	COG2815	serine threonine protein kinase
AUT26_18715	COG3387	PFAM Glycoside hydrolase 15-related
AUT26_18735	COG2814	Major facilitator Superfamily
AUT26_18745	COG0243	molybdopterin cofactor binding
AUT26_18760	COG2261	transglycosylase associated protein
AUT26_18765	COG0515	serine threonine protein kinase
AUT26_18770	COG1846	Transcriptional regulator
AUT26_18850	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AUT26_18855	COG1760	l-serine dehydratase
AUT26_18860	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AUT26_18865	COG0509	glycine decarboxylation via glycine cleavage system
AUT26_18870	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AUT26_18875	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AUT26_18875	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AUT26_18880	COG0318	PFAM AMP-dependent synthetase and ligase
AUT26_18885	COG1970	mechanosensitive ion channel activity
AUT26_18890	COG2271	Major facilitator Superfamily
AUT26_18895	COG1802	Transcriptional regulator
AUT26_18950	COG2963	transposase activity
AUT26_18970	COG3328	transposase activity
AUT26_18985	COG2801	Transposase and inactivated derivatives
AUT26_18985	COG3415	Transposase
AUT26_18995	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AUT26_19000	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AUT26_19005	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AUT26_19020	COG0546	phosphoglycolate phosphatase activity
AUT26_19045	COG1414	Transcriptional regulator
AUT26_19050	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AUT26_19060	COG0183	Belongs to the thiolase family
AUT26_19065	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AUT26_19080	COG3485	protocatechuate 3,4-dioxygenase
AUT26_19085	COG3485	protocatechuate 3,4-dioxygenase
AUT26_19095	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AUT26_19100	COG1414	Transcriptional regulator
AUT26_19105	COG0477	Major facilitator Superfamily
AUT26_19150	COG0646	methionine synthase
AUT26_19150	COG1410	methionine synthase
AUT26_19155	COG1177	transmembrane transport
AUT26_19160	COG4149	molybdate abc transporter
AUT26_19165	COG3842	ATPase activity
AUT26_19175	COG3845	ABC transporter
AUT26_19190	COG2259	Doxx family
AUT26_19205	COG1929	Belongs to the glycerate kinase type-1 family
AUT26_19215	COG0673	inositol 2-dehydrogenase activity
AUT26_19240	COG4211	Belongs to the binding-protein-dependent transport system permease family
AUT26_19245	COG1172	Belongs to the binding-protein-dependent transport system permease family
AUT26_19250	COG1129	ABC transporter
AUT26_19270	COG1940	carbohydrate kinase activity
AUT26_19280	COG1063	alcohol dehydrogenase
AUT26_19290	COG1175	transmembrane transport
AUT26_19300	COG0673	inositol 2-dehydrogenase activity
AUT26_19320	COG2801	Transposase and inactivated derivatives
AUT26_19330	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AUT26_19335	COG3386	PFAM SMP-30 Gluconolaconase
AUT26_19340	COG4948	Mandelate Racemase Muconate Lactonizing
AUT26_19360	COG1461	Dihydroxyacetone kinase
AUT26_19365	COG2376	Dihydroxyacetone kinase
AUT26_19380	COG1172	Belongs to the binding-protein-dependent transport system permease family
AUT26_19385	COG1172	Belongs to the binding-protein-dependent transport system permease family
AUT26_19390	COG1879	ABC-type sugar transport system periplasmic component
AUT26_19400	COG0800	Aldolase
AUT26_19425	COG1846	Transcriptional regulator
AUT26_19430	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AUT26_19450	COG1335	isochorismatase
AUT26_19460	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AUT26_19470	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AUT26_19505	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AUT26_19515	COG0588	phosphoglycerate mutase activity
AUT26_19525	COG1063	alcohol dehydrogenase
AUT26_19530	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AUT26_19535	COG2159	amidohydrolase
AUT26_19545	COG1802	Transcriptional regulator
AUT26_19550	COG1335	isochorismatase
AUT26_19560	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AUT26_19565	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AUT26_19570	COG1116	anion transmembrane transporter activity
AUT26_19575	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AUT26_19610	COG2149	membrane
AUT26_19615	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AUT26_19620	COG1940	carbohydrate kinase activity
AUT26_19630	COG1175	transmembrane transport
AUT26_19635	COG0395	ABC-type sugar transport system, permease component
AUT26_19655	COG0477	Major facilitator Superfamily
AUT26_19670	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AUT26_19685	COG2124	cytochrome p450
AUT26_19695	COG1414	Transcriptional regulator
AUT26_19705	COG1012	belongs to the aldehyde dehydrogenase family
AUT26_19710	COG1234	tRNA 3'-trailer cleavage
AUT26_19750	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AUT26_19770	COG1028	Short-chain dehydrogenase reductase Sdr
AUT26_19775	COG1309	transcriptional regulator
AUT26_19780	COG1116	anion transmembrane transporter activity
AUT26_19785	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AUT26_19790	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AUT26_19795	COG1116	anion transmembrane transporter activity
AUT26_19795	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AUT26_19800	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AUT26_19825	COG3384	dioxygenase
AUT26_19835	COG0583	DNA-binding transcription factor activity
AUT26_19930	COG1937	Protein conserved in bacteria
AUT26_19975	COG0534	Mate efflux family protein
AUT26_19985	COG1607	acyl-coa hydrolase
AUT26_20000	COG3958	Transketolase
AUT26_20005	COG3959	Transketolase, thiamine diphosphate binding domain
AUT26_20015	COG1082	Xylose isomerase domain protein TIM barrel
AUT26_20020	COG1028	Short-chain dehydrogenase reductase Sdr
AUT26_20025	COG2376	Dihydroxyacetone kinase
AUT26_20030	COG0698	ribose 5-phosphate isomerase
AUT26_20045	COG0305	Participates in initiation and elongation during chromosome replication
AUT26_20100	COG0359	binds to the 23S rRNA
AUT26_20105	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AUT26_20115	COG0360	Binds together with S18 to 16S ribosomal RNA
AUT26_20120	COG1742	UPF0060 membrane protein
AUT26_20145	COG1113	amino acid transport
AUT26_20150	COG1362	aminopeptidase activity
AUT26_20155	COG2197	response regulator
AUT26_20160	COG4585	Histidine kinase
AUT26_20170	COG1131	(ABC) transporter
AUT26_20185	COG0738	Major facilitator superfamily
AUT26_20195	COG0488	(ABC) transporter
AUT26_20205	COG0768	penicillin binding
AUT26_20210	COG2197	response regulator
AUT26_20215	COG4585	Histidine kinase
AUT26_20225	COG1136	(ABC) transporter
AUT26_20230	COG1733	regulation of RNA biosynthetic process
AUT26_20235	COG2910	NAD(P)H-binding
AUT26_20250	COG0406	alpha-ribazole phosphatase activity
AUT26_20255	COG0617	tRNA 3'-terminal CCA addition
AUT26_20275	COG0492	ferredoxin-NADP+ reductase activity
AUT26_20280	COG3118	belongs to the thioredoxin family
AUT26_20290	COG1192	Involved in chromosome partitioning
AUT26_20295	COG0357	Ribosomal RNA small subunit methyltransferase G
AUT26_20305	COG0706	membrane insertase activity
AUT26_20310	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AUT26_20315	COG0230	Belongs to the bacterial ribosomal protein bL34 family