locus-tag	class	description
NVV90_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NVV90_00010	COG0592	DNA-directed DNA polymerase activity
NVV90_00015	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
NVV90_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NVV90_00025	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
NVV90_00030	COG0187	DNA topoisomerase II activity
NVV90_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NVV90_00040	COG3266	domain, Protein
NVV90_00065	COG1215	transferase activity, transferring glycosyl groups
NVV90_00085	COG2818	Glycosylase
NVV90_00095	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NVV90_00115	COG3764	Sortase (surface protein transpeptidase)
NVV90_00135	COG0515	serine threonine protein kinase
NVV90_00140	COG0768	penicillin binding
NVV90_00155	COG1716	ATPase activity
NVV90_00160	COG1716	ATPase activity
NVV90_00185	COG0346	lactoylglutathione lyase activity
NVV90_00195	COG0833	amino acid
NVV90_00205	COG2186	Transcriptional regulator
NVV90_00210	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
NVV90_00220	COG1984	allophanate hydrolase subunit 2
NVV90_00225	COG4770	biotin carboxylase activity
NVV90_00245	COG2205	protein histidine kinase activity
NVV90_00255	COG1609	Transcriptional regulator
NVV90_00260	COG0659	secondary active sulfate transmembrane transporter activity
NVV90_00285	COG0561	phosphatase activity
NVV90_00300	COG4941	Belongs to the sigma-70 factor family
NVV90_00370	COG1929	Belongs to the glycerate kinase type-1 family
NVV90_00380	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NVV90_00395	COG2233	PERMEase
NVV90_00400	COG0492	ferredoxin-NADP+ reductase activity
NVV90_00410	COG0778	Nitroreductase
NVV90_00435	COG3104	oligopeptide transport
NVV90_00440	COG0154	amidase activity
NVV90_00445	COG3340	Belongs to the peptidase S51 family
NVV90_00455	COG0077	Prephenate dehydratase
NVV90_00465	COG1597	lipid kinase activity
NVV90_00470	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NVV90_00475	COG0561	phosphatase activity
NVV90_00515	COG0037	tRNA processing
NVV90_00525	COG1621	beta-fructofuranosidase activity
NVV90_00550	COG0395	ABC-type sugar transport system, permease component
NVV90_00555	COG1609	Transcriptional regulator
NVV90_00560	COG1621	beta-fructofuranosidase activity
NVV90_00565	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NVV90_00575	COG1609	Transcriptional regulator
NVV90_00580	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NVV90_00585	COG0302	gtp cyclohydrolase
NVV90_00595	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NVV90_00625	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NVV90_00630	COG2814	Major facilitator Superfamily
NVV90_00655	COG0287	Prephenate dehydrogenase
NVV90_00655	COG1605	Chorismate mutase
NVV90_00710	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
NVV90_00730	COG0823	Involved in the tonB-independent uptake of proteins
NVV90_00730	COG1506	peptidase
NVV90_00730	COG4946	Tricorn protease homolog
NVV90_00735	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
NVV90_00740	COG2376	Dihydroxyacetone kinase
NVV90_00745	COG1461	Dihydroxyacetone kinase
NVV90_00750	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
NVV90_00820	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
NVV90_00825	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NVV90_00845	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
NVV90_00860	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NVV90_00885	COG3290	protein histidine kinase activity
NVV90_00890	COG4565	transcriptional regulatory protein
NVV90_00900	COG1595	DNA-templated transcription, initiation
NVV90_00905	COG0306	phosphate transporter
NVV90_00930	COG1609	Transcriptional regulator
NVV90_00945	COG2160	L-arabinose isomerase activity
NVV90_00950	COG2017	converts alpha-aldose to the beta-anomer
NVV90_00955	COG1609	Transcriptional regulator
NVV90_00960	COG4214	carbohydrate transport
NVV90_00965	COG1129	ABC transporter
NVV90_00970	COG4213	ABC transporter substrate-binding protein
NVV90_00975	COG3940	Belongs to the glycosyl hydrolase 43 family
NVV90_00980	COG1172	Belongs to the binding-protein-dependent transport system permease family
NVV90_00985	COG1172	Belongs to the binding-protein-dependent transport system permease family
NVV90_00995	COG1879	ABC-type sugar transport system periplasmic component
NVV90_01015	COG0831	urea catabolic process
NVV90_01020	COG0832	Belongs to the urease beta subunit family
NVV90_01025	COG0804	urea catabolic process
NVV90_01030	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
NVV90_01035	COG0830	nickel cation binding
NVV90_01040	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
NVV90_01045	COG0829	nickel cation binding
NVV90_01050	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
NVV90_01080	COG0656	L-ascorbic acid biosynthetic process
NVV90_01085	COG0667	Aldo Keto reductase
NVV90_01090	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
NVV90_01095	COG3360	Dodecin
NVV90_01105	COG0028	Belongs to the TPP enzyme family
NVV90_01110	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
NVV90_01120	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NVV90_01140	COG2186	Transcriptional regulator
NVV90_01155	COG2084	Dehydrogenase
NVV90_01160	COG2610	gluconate transmembrane transporter activity
NVV90_01210	COG0076	glutamate decarboxylase activity
NVV90_01215	COG3486	L-lysine 6-monooxygenase (NADPH) activity
NVV90_01230	COG4941	Belongs to the sigma-70 factor family
NVV90_01235	COG3795	YCII-related domain
NVV90_01240	COG0300	oxidoreductase activity
NVV90_01265	COG1609	Transcriptional regulator
NVV90_01270	COG1305	Transglutaminase-like
NVV90_01300	COG0346	lactoylglutathione lyase activity
NVV90_01305	COG5002	protein histidine kinase activity
NVV90_01310	COG0745	RESPONSE REGULATOR receiver
NVV90_01320	COG0477	Major facilitator Superfamily
NVV90_01325	COG2890	protein-(glutamine-N5) methyltransferase activity
NVV90_01345	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
NVV90_01350	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NVV90_01355	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NVV90_01360	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NVV90_01360	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NVV90_01360	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NVV90_01365	COG1105	Belongs to the carbohydrate kinase PfkB family
NVV90_01370	COG1349	DNA-binding transcription factor activity
NVV90_01405	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NVV90_01430	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NVV90_01440	COG1126	abc transporter atp-binding protein
NVV90_01445	COG0765	amino acid transport
NVV90_01460	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NVV90_01465	COG1012	belongs to the aldehyde dehydrogenase family
NVV90_01470	COG0473	3-isopropylmalate dehydrogenase activity
NVV90_01515	COG0673	inositol 2-dehydrogenase activity
NVV90_01535	COG0395	ABC-type sugar transport system, permease component
NVV90_01540	COG1063	alcohol dehydrogenase
NVV90_01550	COG1609	Transcriptional regulator
NVV90_01595	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
NVV90_01620	COG2733	membrane
NVV90_01655	COG4122	O-methyltransferase activity
NVV90_01680	COG1028	Short-chain dehydrogenase reductase Sdr
NVV90_01685	COG1733	regulation of RNA biosynthetic process
NVV90_01690	COG0702	epimerase
NVV90_01695	COG1280	lysine exporter protein (LysE YggA)
NVV90_01715	COG1476	TRANSCRIPTIONal
NVV90_01720	COG3321	synthase
NVV90_01720	COG1028	Short-chain dehydrogenase reductase Sdr
NVV90_01720	COG0604	alcohol dehydrogenase
NVV90_01730	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NVV90_01750	COG2902	Dehydrogenase
NVV90_01760	COG0010	Belongs to the arginase family
NVV90_01765	COG2252	PERMEase
NVV90_01790	COG0574	Belongs to the PEP-utilizing enzyme family
NVV90_01790	COG3848	Pyruvate phosphate dikinase
NVV90_01815	COG0693	protein deglycase activity
NVV90_01830	COG1609	Transcriptional regulator
NVV90_01835	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NVV90_01865	COG1302	Protein conserved in bacteria
NVV90_01895	COG0366	Alpha amylase catalytic
NVV90_01900	COG1653	transport
NVV90_01905	COG1175	transmembrane transport
NVV90_01910	COG0395	ABC-type sugar transport system, permease component
NVV90_01915	COG1609	Transcriptional regulator
NVV90_01935	COG2197	response regulator
NVV90_01940	COG4585	Histidine kinase
NVV90_01950	COG0666	response to abiotic stimulus
NVV90_01965	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NVV90_01975	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
NVV90_01980	COG1012	belongs to the aldehyde dehydrogenase family
NVV90_02015	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NVV90_02030	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NVV90_02035	COG0303	'Molybdopterin
NVV90_02040	COG1063	alcohol dehydrogenase
NVV90_02050	COG0302	gtp cyclohydrolase
NVV90_02070	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NVV90_02075	COG3404	Formiminotransferase-cyclodeaminase
NVV90_02090	COG1802	Transcriptional regulator
NVV90_02095	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
NVV90_02100	COG0583	DNA-binding transcription factor activity
NVV90_02125	COG1024	Enoyl-CoA hydratase
NVV90_02135	COG1024	Enoyl-CoA hydratase
NVV90_02175	COG0477	Major facilitator Superfamily
NVV90_02180	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NVV90_02185	COG2197	response regulator
NVV90_02195	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NVV90_02200	COG1695	Transcriptional regulator
NVV90_02220	COG1609	Transcriptional regulator
NVV90_02230	COG1175	transmembrane transport
NVV90_02235	COG0395	ABC-type sugar transport system, permease component
NVV90_02245	COG0673	inositol 2-dehydrogenase activity
NVV90_02255	COG1904	glucuronate isomerase
NVV90_02260	COG0246	Mannitol dehydrogenase
NVV90_02265	COG4948	Mandelate Racemase Muconate Lactonizing
NVV90_02270	COG3265	gluconokinase activity
NVV90_02280	COG2186	Transcriptional regulator
NVV90_02290	COG0179	Fumarylacetoacetate (FAA) hydrolase
NVV90_02305	COG2814	Major facilitator Superfamily
NVV90_02310	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NVV90_02315	COG0183	Belongs to the thiolase family
NVV90_02325	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NVV90_02330	COG1414	Transcriptional regulator
NVV90_02335	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NVV90_02345	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NVV90_02360	COG0165	Argininosuccinate lyase
NVV90_02385	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NVV90_02385	COG0357	Ribosomal RNA small subunit methyltransferase G
NVV90_02415	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NVV90_02440	COG1832	CoA-binding protein
NVV90_02450	COG2315	Protein conserved in bacteria
NVV90_02460	COG1653	transport
NVV90_02465	COG1175	transmembrane transport
NVV90_02470	COG0395	ABC-type sugar transport system, permease component
NVV90_02480	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NVV90_02485	COG0047	phosphoribosylformylglycinamidine synthase activity
NVV90_02490	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NVV90_02525	COG0563	adenylate kinase activity
NVV90_02555	COG1846	Transcriptional regulator
NVV90_02575	COG1131	(ABC) transporter
NVV90_02590	COG0519	Catalyzes the synthesis of GMP from XMP
NVV90_02595	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NVV90_02620	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NVV90_02640	COG1012	belongs to the aldehyde dehydrogenase family
NVV90_02655	COG1846	Transcriptional regulator
NVV90_02660	COG1196	nuclear chromosome segregation
NVV90_02660	COG0741	lytic transglycosylase activity
NVV90_02660	COG0739	heme binding
NVV90_02665	COG0386	Belongs to the glutathione peroxidase family
NVV90_02675	COG0300	oxidoreductase activity
NVV90_02680	COG1012	belongs to the aldehyde dehydrogenase family
NVV90_02690	COG2124	cytochrome p450
NVV90_02700	COG2986	histidine ammonia-lyase
NVV90_02740	COG1309	transcriptional regulator
NVV90_02770	COG1116	anion transmembrane transporter activity
NVV90_02775	COG0745	RESPONSE REGULATOR receiver
NVV90_02805	COG1126	abc transporter atp-binding protein
NVV90_02825	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NVV90_02830	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NVV90_02860	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NVV90_02865	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NVV90_02895	COG0395	ABC-type sugar transport system, permease component
NVV90_02900	COG1175	transmembrane transport
NVV90_02905	COG2182	Extracellular solute-binding protein
NVV90_02910	COG4569	acetaldehyde dehydrogenase (acetylating) activity
NVV90_02920	COG1609	Transcriptional regulator
NVV90_02930	COG0673	inositol 2-dehydrogenase activity
NVV90_02935	COG1940	carbohydrate kinase activity
NVV90_02940	COG0673	inositol 2-dehydrogenase activity
NVV90_02950	COG2807	transmembrane transport
NVV90_02955	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
NVV90_02985	COG1309	transcriptional regulator
NVV90_02995	COG0351	phosphomethylpyrimidine kinase
NVV90_03005	COG2205	protein histidine kinase activity
NVV90_03010	COG0745	RESPONSE REGULATOR receiver
NVV90_03015	COG0477	Major facilitator Superfamily
NVV90_03025	COG1090	epimerase
NVV90_03030	COG1309	transcriptional regulator
NVV90_03040	COG0343	queuine tRNA-ribosyltransferase activity
NVV90_03060	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NVV90_03065	COG0251	oxidation-reduction process
NVV90_03070	COG0477	Major facilitator Superfamily
NVV90_03085	COG0477	Major facilitator Superfamily
NVV90_03090	COG0028	Belongs to the TPP enzyme family
NVV90_03095	COG1012	belongs to the aldehyde dehydrogenase family
NVV90_03100	COG1574	metal-dependent hydrolase with the TIM-barrel fold
NVV90_03105	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NVV90_03120	COG3842	ATPase activity
NVV90_03140	COG2837	iron assimilation
NVV90_03150	COG0672	)-iron permease
NVV90_03155	COG0390	transport system, permease component
NVV90_03170	COG1960	acyl-CoA dehydrogenase activity
NVV90_03180	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NVV90_03180	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NVV90_03200	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
NVV90_03215	COG0586	Pfam SNARE associated Golgi protein
NVV90_03230	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NVV90_03235	COG0564	pseudouridine synthase activity
NVV90_03265	COG2364	Membrane
NVV90_03270	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
NVV90_03275	COG1201	RNA secondary structure unwinding
NVV90_03305	COG0569	domain protein
NVV90_03305	COG0475	glutathione-regulated potassium exporter activity
NVV90_03325	COG1228	amidohydrolase
NVV90_03360	COG0697	spore germination
NVV90_03430	COG4974	Belongs to the 'phage' integrase family
NVV90_03475	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NVV90_03490	COG0251	oxidation-reduction process
NVV90_03510	COG3265	gluconokinase activity
NVV90_03530	COG2205	protein histidine kinase activity
NVV90_03535	COG0745	RESPONSE REGULATOR receiver
NVV90_03550	COG0583	DNA-binding transcription factor activity
NVV90_03565	COG1737	Transcriptional regulator
NVV90_03570	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NVV90_03575	COG0247	lactate metabolic process
NVV90_03575	COG0277	FAD linked oxidase domain protein
NVV90_03580	COG0477	Major facilitator Superfamily
NVV90_03585	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
NVV90_03590	COG1309	transcriptional regulator
NVV90_03595	COG1511	domain protein
NVV90_03615	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
NVV90_03620	COG1940	carbohydrate kinase activity
NVV90_03625	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NVV90_03630	COG4608	Belongs to the ABC transporter superfamily
NVV90_03635	COG0444	Belongs to the ABC transporter superfamily
NVV90_03645	COG4533	DNA binding
NVV90_03650	COG2188	Transcriptional regulator
NVV90_03660	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
NVV90_03665	COG1017	nitric oxide dioxygenase activity
NVV90_03665	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NVV90_03670	COG1959	2 iron, 2 sulfur cluster binding
NVV90_03680	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NVV90_03685	COG0514	ATP-dependent DNA helicase (RecQ)
NVV90_03690	COG0477	Major facilitator Superfamily
NVV90_03700	COG1120	ATPase activity
NVV90_03705	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NVV90_03710	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NVV90_03715	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NVV90_03720	COG1505	serine-type exopeptidase activity
NVV90_03730	COG1113	amino acid transport
NVV90_03760	COG3321	synthase
NVV90_03760	COG0604	alcohol dehydrogenase
NVV90_03760	COG1028	Short-chain dehydrogenase reductase Sdr
NVV90_03770	COG1966	Carbon starvation protein
NVV90_03790	COG0656	L-ascorbic acid biosynthetic process
NVV90_03810	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NVV90_03815	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NVV90_03835	COG0588	phosphoglycerate mutase activity
NVV90_03845	COG5002	protein histidine kinase activity
NVV90_03865	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
NVV90_03870	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
NVV90_03880	COG0215	cysteine-tRNA ligase activity
NVV90_03895	COG1802	Transcriptional regulator
NVV90_03930	COG0366	Alpha amylase catalytic
NVV90_03940	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NVV90_03970	COG1609	Transcriptional regulator
NVV90_03975	COG0366	Alpha amylase catalytic
NVV90_03990	COG3833	ABC-type maltose transport systems, permease component
NVV90_03995	COG0366	Alpha amylase catalytic
NVV90_04000	COG0277	FAD linked oxidase domain protein
NVV90_04010	COG0402	S-adenosylhomocysteine deaminase activity
NVV90_04015	COG4608	Belongs to the ABC transporter superfamily
NVV90_04020	COG0444	Belongs to the ABC transporter superfamily
NVV90_04025	COG0601	transmembrane transport
NVV90_04035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NVV90_04055	COG3842	ATPase activity
NVV90_04080	COG0506	proline dehydrogenase activity
NVV90_04105	COG2957	Belongs to the agmatine deiminase family
NVV90_04145	COG2814	Major facilitator Superfamily
NVV90_04190	COG0477	Major facilitator Superfamily
NVV90_04200	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NVV90_04200	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NVV90_04205	COG0404	The glycine cleavage system catalyzes the degradation of glycine
NVV90_04210	COG0509	glycine decarboxylation via glycine cleavage system
NVV90_04215	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NVV90_04225	COG1864	DNA RNA non-specific endonuclease
NVV90_04225	COG3591	Belongs to the peptidase S1B family
NVV90_04250	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NVV90_04270	COG0459	protein refolding
NVV90_04275	COG0328	RNA-DNA hybrid ribonuclease activity
NVV90_04285	COG2205	protein histidine kinase activity
NVV90_04290	COG0745	RESPONSE REGULATOR receiver
NVV90_04300	COG0583	DNA-binding transcription factor activity
NVV90_04325	COG1278	Cold shock
NVV90_04345	COG0739	heme binding
NVV90_04350	COG0791	NLP P60 protein
NVV90_04350	COG1388	LysM domain
NVV90_04350	COG3103	Sh3 type 3 domain protein
NVV90_04365	COG0746	molybdenum cofactor guanylyltransferase activity
NVV90_04375	COG0303	'Molybdopterin
NVV90_04385	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NVV90_04395	COG1126	abc transporter atp-binding protein
NVV90_04400	COG0765	amino acid transport
NVV90_04405	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NVV90_04430	COG1132	(ABC) transporter
NVV90_04495	COG0483	inositol monophosphate 1-phosphatase activity
NVV90_04510	COG0045	succinate-CoA ligase (ADP-forming) activity
NVV90_04525	COG0346	lactoylglutathione lyase activity
NVV90_04535	COG1942	4-Oxalocrotonate Tautomerase
NVV90_04550	COG3962	Belongs to the TPP enzyme family
NVV90_04565	COG0673	inositol 2-dehydrogenase activity
NVV90_04570	COG1082	Xylose isomerase domain protein TIM barrel
NVV90_04590	COG1609	Transcriptional regulator
NVV90_04600	COG1172	Belongs to the binding-protein-dependent transport system permease family
NVV90_04610	COG0673	inositol 2-dehydrogenase activity
NVV90_04615	COG0673	inositol 2-dehydrogenase activity
NVV90_04620	COG0673	inositol 2-dehydrogenase activity
NVV90_04630	COG3718	enzyme involved in inositol metabolism
NVV90_04635	COG2188	Transcriptional regulator
NVV90_04640	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
NVV90_04655	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NVV90_04680	COG1760	l-serine dehydratase
NVV90_04720	COG1396	sequence-specific DNA binding
NVV90_04735	COG0028	Belongs to the TPP enzyme family
NVV90_04755	COG0477	Major facilitator Superfamily
NVV90_04775	COG3142	Participates in the control of copper homeostasis
NVV90_04780	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NVV90_04785	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
NVV90_04790	COG0492	ferredoxin-NADP+ reductase activity
NVV90_04795	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NVV90_04830	COG1401	restriction endodeoxyribonuclease activity
NVV90_04850	COG0463	Glycosyl transferase, family 2
NVV90_04865	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
NVV90_04875	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NVV90_04880	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NVV90_04910	COG1902	pentaerythritol trinitrate reductase activity
NVV90_04925	COG2376	Dihydroxyacetone kinase
NVV90_04930	COG0698	ribose 5-phosphate isomerase
NVV90_04935	COG1250	3-hydroxyacyl-CoA dehydrogenase
NVV90_04940	COG1028	Short-chain dehydrogenase reductase Sdr
NVV90_04945	COG2271	Major facilitator Superfamily
NVV90_04950	COG0149	triose-phosphate isomerase activity
NVV90_04980	COG1737	Transcriptional regulator
NVV90_05015	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NVV90_05030	COG1254	Belongs to the acylphosphatase family
NVV90_05045	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NVV90_05055	COG3550	peptidyl-serine autophosphorylation
NVV90_05060	COG0640	Transcriptional regulator
NVV90_05080	COG2365	Tyrosine phosphatase family
NVV90_05085	COG3639	organic phosphonate transmembrane transporter activity
NVV90_05090	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
NVV90_05105	COG0477	Major facilitator Superfamily
NVV90_05165	COG1205	dead DEAH box helicase
NVV90_05165	COG1111	helicase
NVV90_05170	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NVV90_05175	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
NVV90_05185	COG1401	restriction endodeoxyribonuclease activity
NVV90_05200	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NVV90_05205	COG0443	Heat shock 70 kDa protein
NVV90_05255	COG2337	Toxic component of a toxin-antitoxin (TA) module
NVV90_05280	COG4942	peptidase
NVV90_05285	COG1278	Cold shock
NVV90_05300	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NVV90_05315	COG2268	Band 7 protein
NVV90_05350	COG2271	Major facilitator Superfamily
NVV90_05355	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NVV90_05365	COG0138	bifunctional purine biosynthesis protein purh
NVV90_05375	COG2838	Isocitrate dehydrogenase
NVV90_05390	COG0673	inositol 2-dehydrogenase activity
NVV90_05400	COG0577	efflux transmembrane transporter activity
NVV90_05400	COG1136	(ABC) transporter
NVV90_05405	COG0577	efflux transmembrane transporter activity
NVV90_05405	COG1136	(ABC) transporter
NVV90_05410	COG1136	(ABC) transporter
NVV90_05415	COG0577	efflux transmembrane transporter activity
NVV90_05415	COG1136	(ABC) transporter
NVV90_05420	COG4213	ABC transporter substrate-binding protein
NVV90_05425	COG1172	Belongs to the binding-protein-dependent transport system permease family
NVV90_05440	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NVV90_05450	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NVV90_05455	COG0531	amino acid
NVV90_05485	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NVV90_05495	COG4585	Histidine kinase
NVV90_05500	COG2197	response regulator
NVV90_05510	COG1131	(ABC) transporter
NVV90_05535	COG0180	Tryptophanyl-tRNA synthetase
NVV90_05555	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NVV90_05570	COG2009	succinate dehydrogenase
NVV90_05580	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
NVV90_05580	COG1473	amidohydrolase
NVV90_05585	COG1846	Transcriptional regulator
NVV90_05590	COG1764	response to oxidative stress
NVV90_05595	COG2130	NADP-dependent
NVV90_05600	COG1744	ABC transporter substrate-binding protein PnrA-like
NVV90_05605	COG3845	ABC transporter
NVV90_05610	COG4603	Belongs to the binding-protein-dependent transport system permease family
NVV90_05615	COG1079	Belongs to the binding-protein-dependent transport system permease family
NVV90_05630	COG0586	Pfam SNARE associated Golgi protein
NVV90_05635	COG0586	Pfam SNARE associated Golgi protein
NVV90_05640	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NVV90_05645	COG3956	TIGRFAM MazG family protein
NVV90_05650	COG0148	phosphopyruvate hydratase activity
NVV90_05675	COG1252	NADH dehydrogenase
NVV90_05690	COG0683	leucine binding
NVV90_05720	COG0183	Belongs to the thiolase family
NVV90_05725	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NVV90_05735	COG2017	converts alpha-aldose to the beta-anomer
NVV90_05745	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NVV90_05755	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NVV90_05765	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NVV90_05775	COG1331	Highly conserved protein containing a thioredoxin domain
NVV90_05785	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NVV90_05790	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
NVV90_05825	COG0114	fumarate hydratase activity
NVV90_05840	COG1494	fructose-1,6-bisphosphatase
NVV90_05855	COG1482	cell wall glycoprotein biosynthetic process
NVV90_05865	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NVV90_05915	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
NVV90_05970	COG0714	Associated with various cellular activities
NVV90_05975	COG0084	hydrolase, TatD family'
NVV90_05980	COG3583	domain protein
NVV90_05985	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
NVV90_05990	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NVV90_05995	COG0488	(ABC) transporter
NVV90_06000	COG1309	transcriptional regulator
NVV90_06010	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NVV90_06015	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NVV90_06020	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NVV90_06025	COG0193	aminoacyl-tRNA hydrolase activity
NVV90_06050	COG0822	iron-sulfur transferase activity
NVV90_06055	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NVV90_06075	COG1988	membrane-bound metal-dependent
NVV90_06090	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NVV90_06135	COG1609	Transcriptional regulator
NVV90_06140	COG2814	Major facilitator Superfamily
NVV90_06150	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NVV90_06150	COG1648	precorrin-2 dehydrogenase activity
NVV90_06155	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NVV90_06165	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NVV90_06170	COG1621	beta-fructofuranosidase activity
NVV90_06210	COG0243	molybdopterin cofactor binding
NVV90_06215	COG2223	nitrite transmembrane transporter activity
NVV90_06220	COG0477	Major facilitator Superfamily
NVV90_06230	COG4770	biotin carboxylase activity
NVV90_06255	COG0424	maF-like protein
NVV90_06270	COG2409	Drug exporters of the RND superfamily
NVV90_06275	COG1309	transcriptional regulator
NVV90_06295	COG0393	Putative heavy-metal-binding
NVV90_06300	COG1823	symporter activity
NVV90_06315	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NVV90_06320	COG1028	Short-chain dehydrogenase reductase Sdr
NVV90_06350	COG0714	Associated with various cellular activities
NVV90_06370	COG0631	protein serine/threonine phosphatase activity
NVV90_06390	COG1674	ftsk spoiiie
NVV90_06400	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NVV90_06405	COG0483	inositol monophosphate 1-phosphatase activity
NVV90_06410	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NVV90_06420	COG0251	oxidation-reduction process
NVV90_06425	COG4565	transcriptional regulatory protein
NVV90_06435	COG2851	Citrate transporter
NVV90_06440	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NVV90_06445	COG0154	amidase activity
NVV90_06450	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NVV90_06460	COG1262	PFAM Formylglycine-generating sulfatase enzyme
NVV90_06465	COG4209	transmembrane transport
NVV90_06470	COG0395	ABC-type sugar transport system, permease component
NVV90_06485	COG0673	inositol 2-dehydrogenase activity
NVV90_06490	COG0583	DNA-binding transcription factor activity
NVV90_06495	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NVV90_06500	COG1063	alcohol dehydrogenase
NVV90_06505	COG0156	8-amino-7-oxononanoate synthase activity
NVV90_06515	COG1228	amidohydrolase
NVV90_06520	COG0366	Alpha amylase catalytic
NVV90_06520	COG1470	cell adhesion involved in biofilm formation
NVV90_06525	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NVV90_06540	COG0191	fructose-bisphosphate aldolase activity
NVV90_06550	COG0588	phosphoglycerate mutase activity
NVV90_06565	COG2873	o-acetylhomoserine
NVV90_06570	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NVV90_06605	COG0423	glycine-tRNA ligase activity
NVV90_06635	COG0358	DNA primase activity
NVV90_06660	COG2814	Major facilitator Superfamily
NVV90_06710	COG0052	Belongs to the universal ribosomal protein uS2 family
NVV90_06715	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NVV90_06720	COG0528	UMP kinase activity
NVV90_06725	COG0233	cytoplasmic translational termination
NVV90_06730	COG0575	Belongs to the CDS family
NVV90_06745	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NVV90_06755	COG3279	Response regulator of the LytR AlgR family
NVV90_06760	COG3275	phosphorelay sensor kinase activity
NVV90_06770	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NVV90_06775	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
NVV90_06775	COG1796	DNA polymerase
NVV90_06805	COG0022	dehydrogenase e1 component
NVV90_06810	COG0508	dehydrogenase complex catalyzes the overall conversion of
NVV90_06815	COG1309	transcriptional regulator
NVV90_06820	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NVV90_06830	COG1960	acyl-CoA dehydrogenase activity
NVV90_06870	COG0673	inositol 2-dehydrogenase activity
NVV90_06880	COG1175	transmembrane transport
NVV90_06900	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
NVV90_06905	COG0750	zinc metalloprotease
NVV90_06915	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NVV90_06930	COG1309	transcriptional regulator
NVV90_06950	COG0442	prolyl-tRNA aminoacylation
NVV90_06960	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
NVV90_06980	COG0779	Required for maturation of 30S ribosomal subunits
NVV90_06995	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NVV90_06995	COG0481	GTPase activity
NVV90_07000	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NVV90_07005	COG0436	Aminotransferase
NVV90_07010	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NVV90_07030	COG3483	tryptophan 2,3-dioxygenase activity
NVV90_07035	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NVV90_07040	COG1185	polyribonucleotide nucleotidyltransferase activity
NVV90_07045	COG0612	Peptidase, M16
NVV90_07055	COG0488	(ABC) transporter
NVV90_07080	COG0745	RESPONSE REGULATOR receiver
NVV90_07085	COG5002	protein histidine kinase activity
NVV90_07105	COG0521	Mo-molybdopterin cofactor biosynthetic process
NVV90_07115	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
NVV90_07150	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NVV90_07155	COG1674	ftsk spoiiie
NVV90_07165	COG1058	Belongs to the CinA family
NVV90_07165	COG1546	Belongs to the CinA family
NVV90_07170	COG1396	sequence-specific DNA binding
NVV90_07185	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NVV90_07190	COG2137	regulation of response to DNA damage stimulus
NVV90_07195	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NVV90_07200	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NVV90_07205	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NVV90_07210	COG2813	Specifically methylates the guanine in position
NVV90_07215	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NVV90_07230	COG2801	Transposase and inactivated derivatives
NVV90_07235	COG3547	Transposase (IS116 IS110 IS902 family)
NVV90_07245	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NVV90_07250	COG1388	LysM domain
NVV90_07255	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NVV90_07260	COG0131	Imidazoleglycerol-phosphate dehydratase
NVV90_07265	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NVV90_07275	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NVV90_07295	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NVV90_07300	COG0291	Belongs to the bacterial ribosomal protein bL35 family
NVV90_07305	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NVV90_07310	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NVV90_07315	COG2261	transglycosylase associated protein
NVV90_07325	COG2814	Major facilitator Superfamily
NVV90_07330	COG0494	nUDIX hydrolase
NVV90_07360	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NVV90_07365	COG0072	phenylalanine-tRNA ligase activity
NVV90_07365	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NVV90_07370	COG3591	Belongs to the peptidase S1B family
NVV90_07400	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NVV90_07405	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NVV90_07410	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
NVV90_07415	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NVV90_07420	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NVV90_07425	COG1438	arginine binding
NVV90_07430	COG0137	argininosuccinate synthase activity
NVV90_07435	COG0165	Argininosuccinate lyase
NVV90_07450	COG2094	Belongs to the DNA glycosylase MPG family
NVV90_07455	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NVV90_07465	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NVV90_07495	COG0647	UMP catabolic process
NVV90_07510	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NVV90_07515	COG0497	DNA recombination
NVV90_07520	COG0504	CTP synthase activity
NVV90_07525	COG0494	nUDIX hydrolase
NVV90_07555	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
NVV90_07560	COG2079	MmgE PrpD family protein
NVV90_07575	COG3290	protein histidine kinase activity
NVV90_07580	COG1301	dicarboxylic acid transport
NVV90_07600	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NVV90_07605	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NVV90_07615	COG0287	Prephenate dehydrogenase
NVV90_07620	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
NVV90_07630	COG1160	GTP binding
NVV90_07650	COG1846	Transcriptional regulator
NVV90_07655	COG2814	Major facilitator Superfamily
NVV90_07665	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
NVV90_07670	COG0509	glycine decarboxylation via glycine cleavage system
NVV90_07675	COG1716	ATPase activity
NVV90_07695	COG1192	Involved in chromosome partitioning
NVV90_07700	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
NVV90_07710	COG1940	carbohydrate kinase activity
NVV90_07730	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
NVV90_07735	COG2815	serine threonine protein kinase
NVV90_07735	COG0515	serine threonine protein kinase
NVV90_07740	COG1388	LysM domain
NVV90_07740	COG3942	CHAP domain
NVV90_07750	COG0142	geranyltranstransferase activity
NVV90_07760	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NVV90_07770	COG2001	Belongs to the MraZ family
NVV90_07775	COG0275	rRNA processing
NVV90_07785	COG0768	penicillin binding
NVV90_07800	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NVV90_07805	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NVV90_07815	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NVV90_07820	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NVV90_07830	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NVV90_07835	COG1496	oxidoreductase activity
NVV90_07845	COG1799	cell septum assembly
NVV90_07860	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NVV90_07890	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NVV90_07895	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NVV90_07900	COG1028	Short-chain dehydrogenase reductase Sdr
NVV90_07920	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
NVV90_07925	COG0174	glutamine synthetase
NVV90_07930	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
NVV90_07955	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NVV90_07960	COG0321	lipoyl(octanoyl) transferase activity
NVV90_07970	COG1090	epimerase
NVV90_07975	COG0793	Belongs to the peptidase S41A family
NVV90_07975	COG4946	Tricorn protease homolog
NVV90_07980	COG1764	response to oxidative stress
NVV90_07995	COG0508	dehydrogenase complex catalyzes the overall conversion of
NVV90_08000	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NVV90_08005	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NVV90_08025	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NVV90_08055	COG1271	oxidase subunit
NVV90_08060	COG1294	oxidase, subunit
NVV90_08065	COG4988	ABC transporter
NVV90_08085	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NVV90_08090	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NVV90_08090	COG0045	succinate-CoA ligase (ADP-forming) activity
NVV90_08090	COG1042	CoA-binding domain protein
NVV90_08105	COG1435	thymidine kinase activity
NVV90_08125	COG0756	dUTP diphosphatase activity
NVV90_08150	COG0569	domain protein
NVV90_08155	COG0531	amino acid
NVV90_08160	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NVV90_08165	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NVV90_08195	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NVV90_08215	COG0667	Aldo Keto reductase
NVV90_08220	COG1024	Enoyl-CoA hydratase
NVV90_08220	COG1250	3-hydroxyacyl-CoA dehydrogenase
NVV90_08225	COG0183	Belongs to the thiolase family
NVV90_08255	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NVV90_08270	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NVV90_08295	COG0531	amino acid
NVV90_08340	COG0242	peptide deformylase activity
NVV90_08345	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NVV90_08355	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NVV90_08375	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NVV90_08375	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NVV90_08385	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
NVV90_08390	COG0140	phosphoribosyl-ATP diphosphatase activity
NVV90_08395	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
NVV90_08400	COG0107	imidazoleglycerol-phosphate synthase activity
NVV90_08410	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NVV90_08430	COG0134	indole-3-glycerol-phosphate synthase activity
NVV90_08435	COG0133	tryptophan synthase activity
NVV90_08440	COG0159	tryptophan synthase activity
NVV90_08445	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NVV90_08450	COG0069	glutamate synthase activity
NVV90_08450	COG0067	glutamate synthase
NVV90_08450	COG0070	glutamate synthase
NVV90_08460	COG0469	pyruvate kinase activity
NVV90_08515	COG0833	amino acid
NVV90_08520	COG0460	homoserine dehydrogenase
NVV90_08525	COG1012	belongs to the aldehyde dehydrogenase family
NVV90_08570	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NVV90_08580	COG1126	abc transporter atp-binding protein
NVV90_08585	COG0765	amino acid transport
NVV90_08595	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NVV90_08600	COG1028	Short-chain dehydrogenase reductase Sdr
NVV90_08610	COG0251	oxidation-reduction process
NVV90_08620	COG0277	FAD linked oxidase domain protein
NVV90_08620	COG0247	lactate metabolic process
NVV90_08630	COG2828	Protein conserved in bacteria
NVV90_08640	COG0477	Major facilitator Superfamily
NVV90_08645	COG0235	Class ii aldolase
NVV90_08665	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NVV90_08670	COG0477	Major facilitator Superfamily
NVV90_08680	COG0800	Aldolase
NVV90_08690	COG1609	Transcriptional regulator
NVV90_08735	COG0395	ABC-type sugar transport system, permease component
NVV90_08755	COG3328	transposase activity
NVV90_08780	COG2267	carboxylic ester hydrolase activity
NVV90_08805	COG0183	Belongs to the thiolase family
NVV90_08810	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NVV90_08820	COG1024	Enoyl-CoA hydratase
NVV90_08835	COG1609	Transcriptional regulator
NVV90_08840	COG2182	Extracellular solute-binding protein
NVV90_08845	COG1175	transmembrane transport
NVV90_08850	COG0395	ABC-type sugar transport system, permease component
NVV90_08865	COG3250	beta-galactosidase activity
NVV90_08875	COG3328	transposase activity
NVV90_08895	COG2801	Transposase and inactivated derivatives
NVV90_08900	COG2801	Transposase and inactivated derivatives
NVV90_08915	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
NVV90_08925	COG1335	isochorismatase
NVV90_08945	COG3654	unkown
NVV90_08960	COG2132	Multicopper oxidase
NVV90_09045	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
NVV90_09085	COG0655	NAD(P)H dehydrogenase (quinone) activity
NVV90_09095	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NVV90_09130	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NVV90_09140	COG2226	methyltransferase
NVV90_09155	COG2207	Transcriptional regulator
NVV90_09175	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NVV90_09180	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NVV90_09210	COG0395	ABC-type sugar transport system, permease component
NVV90_09215	COG1472	Belongs to the glycosyl hydrolase 3 family
NVV90_09225	COG1609	Transcriptional regulator
NVV90_09230	COG3534	alpha-L-arabinofuranosidase
NVV90_09270	COG4209	transmembrane transport
NVV90_09275	COG0395	ABC-type sugar transport system, permease component
NVV90_09305	COG1609	Transcriptional regulator
NVV90_09335	COG0179	Fumarylacetoacetate (FAA) hydrolase
NVV90_09380	COG1609	Transcriptional regulator
NVV90_09385	COG2814	Major facilitator Superfamily
NVV90_09405	COG0183	Belongs to the thiolase family
NVV90_09410	COG2902	Dehydrogenase
NVV90_09420	COG0633	Ferredoxin
NVV90_09420	COG0543	2 iron, 2 sulfur cluster binding
NVV90_09425	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NVV90_09430	COG1522	sequence-specific DNA binding
NVV90_09445	COG3547	Transposase (IS116 IS110 IS902 family)
NVV90_09460	COG1070	Carbohydrate kinase
NVV90_09465	COG2115	Belongs to the xylose isomerase family
NVV90_09470	COG0277	FAD linked oxidase domain protein
NVV90_09475	COG1940	carbohydrate kinase activity
NVV90_09490	COG1028	Short-chain dehydrogenase reductase Sdr
NVV90_09490	COG3347	Dehydrogenase
NVV90_09495	COG1070	Carbohydrate kinase
NVV90_09500	COG2084	Dehydrogenase
NVV90_09505	COG1082	Xylose isomerase domain protein TIM barrel
NVV90_09510	COG0149	triose-phosphate isomerase activity
NVV90_09515	COG0698	ribose 5-phosphate isomerase
NVV90_09520	COG2376	Dihydroxyacetone kinase
NVV90_09530	COG2186	Transcriptional regulator
NVV90_09540	COG1028	Short-chain dehydrogenase reductase Sdr
NVV90_09545	COG1309	transcriptional regulator
NVV90_09555	COG0601	transmembrane transport
NVV90_09560	COG0444	Belongs to the ABC transporter superfamily
NVV90_09565	COG4608	Belongs to the ABC transporter superfamily
NVV90_09570	COG2723	6-phospho-beta-galactosidase activity
NVV90_09580	COG3507	Belongs to the glycosyl hydrolase 43 family
NVV90_09585	COG3250	beta-galactosidase activity
NVV90_09600	COG0450	alkyl hydroperoxide reductase
NVV90_09630	COG1028	Short-chain dehydrogenase reductase Sdr
NVV90_09640	COG1053	succinate dehydrogenase
NVV90_09655	COG2271	Major facilitator Superfamily
NVV90_09665	COG1960	acyl-CoA dehydrogenase activity
NVV90_09670	COG1250	3-hydroxyacyl-CoA dehydrogenase
NVV90_09675	COG1024	Enoyl-CoA hydratase
NVV90_09690	COG0583	DNA-binding transcription factor activity
NVV90_09695	COG2855	membrane
NVV90_09700	COG1028	Short-chain dehydrogenase reductase Sdr
NVV90_09705	COG0596	Alpha beta hydrolase
NVV90_09725	COG1028	Short-chain dehydrogenase reductase Sdr
NVV90_09730	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NVV90_09750	COG0439	Biotin carboxylase
NVV90_09755	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
NVV90_09790	COG2124	cytochrome p450
NVV90_09800	COG0183	Belongs to the thiolase family
NVV90_09820	COG0583	DNA-binding transcription factor activity
NVV90_09830	COG0598	Magnesium transport protein CorA
NVV90_09840	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
NVV90_09845	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
NVV90_09850	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
NVV90_09870	COG1960	acyl-CoA dehydrogenase activity
NVV90_09875	COG0183	Belongs to the thiolase family
NVV90_09880	COG1414	Transcriptional regulator
NVV90_09890	COG3485	protocatechuate 3,4-dioxygenase
NVV90_09910	COG0318	PFAM AMP-dependent synthetase and ligase
NVV90_09940	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NVV90_09945	COG4172	Belongs to the ABC transporter superfamily
NVV90_09950	COG0405	Gamma-glutamyltransferase
NVV90_09995	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NVV90_10000	COG1846	Transcriptional regulator
NVV90_10015	COG1643	Atp-dependent helicase
NVV90_10045	COG0009	L-threonylcarbamoyladenylate synthase
NVV90_10065	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NVV90_10070	COG2971	BadF BadG BcrA BcrD
NVV90_10075	COG2188	Transcriptional regulator
NVV90_10090	COG3483	tryptophan 2,3-dioxygenase activity
NVV90_10120	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NVV90_10125	COG2050	protein possibly involved in aromatic compounds catabolism
NVV90_10135	COG4552	Acetyltransferase involved in intracellular survival and related
NVV90_10145	COG0539	negative regulation of cytoplasmic translation
NVV90_10160	COG1739	Uncharacterized protein family UPF0029
NVV90_10165	COG0237	dephospho-CoA kinase activity
NVV90_10165	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NVV90_10170	COG0556	nucleotide-excision repair
NVV90_10180	COG0477	Major facilitator Superfamily
NVV90_10195	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NVV90_10205	COG4106	trans-aconitate 2-methyltransferase activity
NVV90_10220	COG0546	phosphoglycolate phosphatase activity
NVV90_10230	COG0322	excinuclease ABC activity
NVV90_10235	COG1660	Displays ATPase and GTPase activities
NVV90_10245	COG1481	regulation of sporulation
NVV90_10250	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NVV90_10255	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NVV90_10260	COG0126	phosphoglycerate kinase activity
NVV90_10265	COG0149	triose-phosphate isomerase activity
NVV90_10270	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NVV90_10280	COG0363	glucosamine-6-phosphate deaminase activity
NVV90_10295	COG0166	Belongs to the GPI family
NVV90_10300	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NVV90_10310	COG0109	protoheme IX farnesyltransferase activity
NVV90_10315	COG1612	heme a metabolic process
NVV90_10325	COG1131	(ABC) transporter
NVV90_10340	COG0719	Fe-S assembly protein
NVV90_10350	COG0396	ATPase activity
NVV90_10355	COG2151	metal-sulfur cluster biosynthetic enzyme
NVV90_10365	COG0318	PFAM AMP-dependent synthetase and ligase
NVV90_10380	COG1122	ATPase activity
NVV90_10390	COG0488	(ABC) transporter
NVV90_10415	COG1028	Short-chain dehydrogenase reductase Sdr
NVV90_10420	COG1028	Short-chain dehydrogenase reductase Sdr
NVV90_10425	COG0560	Phosphoserine phosphatase
NVV90_10425	COG3830	Belongs to the UPF0237 family
NVV90_10430	COG1119	ATPase activity
NVV90_10445	COG0254	rRNA binding
NVV90_10460	COG2855	membrane
NVV90_10485	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NVV90_10490	COG0297	glycogen (starch) synthase activity
NVV90_10510	COG1028	Short-chain dehydrogenase reductase Sdr
NVV90_10525	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NVV90_10545	COG0667	Aldo Keto reductase
NVV90_10550	COG1968	undecaprenyl-diphosphatase activity
NVV90_10555	COG0215	cysteine-tRNA ligase activity
NVV90_10565	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NVV90_10570	COG0517	IMP dehydrogenase activity
NVV90_10570	COG1994	Peptidase M50
NVV90_10580	COG1222	aaa ATPase
NVV90_10585	COG4122	O-methyltransferase activity
NVV90_10595	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
NVV90_10600	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
NVV90_10605	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
NVV90_10610	COG0545	Peptidyl-prolyl cis-trans isomerase
NVV90_10630	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NVV90_10635	COG0805	protein transport
NVV90_10640	COG4581	dead DEAH box helicase
NVV90_10645	COG1574	metal-dependent hydrolase with the TIM-barrel fold
NVV90_10650	COG1216	Glycosyl transferase, family 2
NVV90_10675	COG0242	peptide deformylase activity
NVV90_10700	COG3424	synthase
NVV90_10730	COG2362	D-Aminopeptidase
NVV90_10755	COG4948	Mandelate Racemase Muconate Lactonizing
NVV90_10760	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NVV90_10760	COG2508	Transcriptional regulator
NVV90_10785	COG4608	Belongs to the ABC transporter superfamily
NVV90_10845	COG0601	transmembrane transport
NVV90_10850	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NVV90_10885	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NVV90_10885	COG2508	Transcriptional regulator
NVV90_10890	COG4948	Mandelate Racemase Muconate Lactonizing
NVV90_10915	COG2362	D-Aminopeptidase
NVV90_10985	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NVV90_10990	COG1845	cytochrome c oxidase, subunit III
NVV90_10995	COG2010	Cytochrome c
NVV90_11000	COG0723	plastoquinol--plastocyanin reductase activity
NVV90_11005	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
NVV90_11010	COG2186	Transcriptional regulator
NVV90_11025	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NVV90_11030	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NVV90_11050	COG0167	dihydroorotate dehydrogenase activity
NVV90_11070	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NVV90_11075	COG1381	Involved in DNA repair and RecF pathway recombination
NVV90_11080	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NVV90_11085	COG3590	peptidase
NVV90_11090	COG1316	TRANSCRIPTIONal
NVV90_11095	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NVV90_11105	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NVV90_11120	COG1385	rRNA (uridine-N3-)-methyltransferase activity
NVV90_11125	COG0484	heat shock protein binding
NVV90_11130	COG1420	regulation of RNA biosynthetic process
NVV90_11150	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NVV90_11155	COG0481	GTPase activity
NVV90_11165	COG0268	Binds directly to 16S ribosomal RNA
NVV90_11185	COG1307	EDD domain protein, DegV family
NVV90_11190	COG0495	leucyl-tRNA aminoacylation
NVV90_11215	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NVV90_11220	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NVV90_11225	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NVV90_11230	COG2390	Transcriptional regulator
NVV90_11235	COG0656	L-ascorbic acid biosynthetic process
NVV90_11255	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NVV90_11265	COG1758	RNA polymerase activity
NVV90_11270	COG0194	GDP metabolic process
NVV90_11280	COG0284	orotidine-5'-phosphate decarboxylase activity
NVV90_11285	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NVV90_11290	COG0505	Belongs to the CarA family
NVV90_11300	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NVV90_11305	COG0540	Belongs to the ATCase OTCase family
NVV90_11310	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NVV90_11320	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NVV90_11325	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NVV90_11335	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NVV90_11340	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NVV90_11345	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NVV90_11350	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NVV90_11360	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NVV90_11365	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NVV90_11380	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NVV90_11405	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NVV90_11410	COG0124	histidyl-tRNA synthetase
NVV90_11415	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NVV90_11420	COG1196	nuclear chromosome segregation
NVV90_11430	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NVV90_11435	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NVV90_11440	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NVV90_11450	COG2255	four-way junction helicase activity
NVV90_11455	COG0632	four-way junction helicase activity
NVV90_11460	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
NVV90_11465	COG0217	transcriptional regulatory protein
NVV90_11470	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
NVV90_11475	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NVV90_11495	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
NVV90_11500	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NVV90_11510	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NVV90_11515	COG0587	DNA-directed DNA polymerase activity
NVV90_11525	COG0384	phenazine biosynthesis protein PhzF
NVV90_11535	COG2135	peptidase activity
NVV90_11550	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NVV90_11620	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NVV90_11625	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NVV90_11630	COG1780	Probably involved in ribonucleotide reductase function
NVV90_11640	COG0583	DNA-binding transcription factor activity
NVV90_11650	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NVV90_11675	COG1175	transmembrane transport
NVV90_11690	COG2813	Specifically methylates the guanine in position
NVV90_11710	COG1028	Short-chain dehydrogenase reductase Sdr
NVV90_11730	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NVV90_11740	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NVV90_11745	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NVV90_11750	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NVV90_11755	COG0211	Belongs to the bacterial ribosomal protein bL27 family
NVV90_11760	COG0261	This protein binds to 23S rRNA in the presence of protein L20
NVV90_11765	COG0352	thiamine-phosphate diphosphorylase activity
NVV90_11765	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NVV90_11765	COG0351	phosphomethylpyrimidine kinase
NVV90_11770	COG1530	ribonuclease E activity
NVV90_11780	COG0105	UTP biosynthetic process
NVV90_11790	COG0285	dihydrofolate synthase activity
NVV90_11795	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NVV90_11810	COG0525	valine-tRNA ligase activity
NVV90_11815	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
NVV90_11820	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
NVV90_11825	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NVV90_11830	COG0740	serine-type endopeptidase activity
NVV90_11835	COG0740	serine-type endopeptidase activity
NVV90_11840	COG0544	peptidyl-prolyl cis-trans isomerase activity
NVV90_11885	COG0668	transmembrane transport
NVV90_11900	COG1946	Acyl-CoA thioesterase
NVV90_11915	COG0629	single-stranded DNA binding
NVV90_11935	COG0739	heme binding
NVV90_12065	COG0242	peptide deformylase activity
NVV90_12095	COG3022	response to hydroperoxide
NVV90_12105	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NVV90_12110	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NVV90_12120	COG1045	serine acetyltransferase
NVV90_12125	COG1028	Short-chain dehydrogenase reductase Sdr
NVV90_12130	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NVV90_12140	COG1063	alcohol dehydrogenase
NVV90_12145	COG1028	Short-chain dehydrogenase reductase Sdr
NVV90_12155	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NVV90_12160	COG0477	Major facilitator Superfamily
NVV90_12205	COG0210	DNA helicase
NVV90_12295	COG0443	Heat shock 70 kDa protein
NVV90_12300	COG0484	heat shock protein binding
NVV90_12370	COG1674	ftsk spoiiie
NVV90_12475	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
NVV90_12490	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NVV90_12495	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NVV90_12520	COG0792	nuclease activity
NVV90_12530	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NVV90_12540	COG0681	Belongs to the peptidase S26 family
NVV90_12545	COG0335	large ribosomal subunit rRNA binding
NVV90_12550	COG0336	Belongs to the RNA methyltransferase TrmD family
NVV90_12555	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NVV90_12560	COG1837	Belongs to the UPF0109 family
NVV90_12565	COG0228	four-way junction DNA binding
NVV90_12575	COG2514	catechol 2,3-dioxygenase activity
NVV90_12600	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NVV90_12640	COG0604	alcohol dehydrogenase
NVV90_12640	COG3321	synthase
NVV90_12655	COG1309	transcriptional regulator
NVV90_12660	COG0667	Aldo Keto reductase
NVV90_12680	COG0395	ABC-type sugar transport system, permease component
NVV90_12695	COG1609	Transcriptional regulator
NVV90_12710	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
NVV90_12715	COG0571	ribonuclease III activity
NVV90_12720	COG0333	Belongs to the bacterial ribosomal protein bL32 family
NVV90_12730	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NVV90_12745	COG0742	ribosomal rna small subunit methyltransferase
NVV90_12765	COG1316	TRANSCRIPTIONal
NVV90_12775	COG1181	Belongs to the D-alanine--D-alanine ligase family
NVV90_12780	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
NVV90_12790	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NVV90_12795	COG0066	3-isopropylmalate dehydratase activity
NVV90_12800	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NVV90_12805	COG1414	Transcriptional regulator
NVV90_12845	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NVV90_12850	COG0179	Fumarylacetoacetate (FAA) hydrolase
NVV90_12855	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NVV90_12875	COG5002	protein histidine kinase activity
NVV90_12880	COG0745	RESPONSE REGULATOR receiver
NVV90_12885	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NVV90_12890	COG0473	3-isopropylmalate dehydrogenase activity
NVV90_12895	COG4585	Histidine kinase
NVV90_12900	COG2197	response regulator
NVV90_12905	COG1136	(ABC) transporter
NVV90_12920	COG1136	(ABC) transporter
NVV90_12920	COG0577	efflux transmembrane transporter activity
NVV90_12930	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NVV90_12935	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NVV90_12940	COG0440	acetolactate synthase activity
NVV90_12950	COG0129	dihydroxy-acid dehydratase activity
NVV90_12960	COG0088	Forms part of the polypeptide exit tunnel
NVV90_12965	COG2133	pyrroloquinoline quinone binding
NVV90_12995	COG0747	negative chemotaxis
NVV90_13000	COG0579	oxidoreductase
NVV90_13005	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NVV90_13010	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NVV90_13020	COG1305	Transglutaminase-like
NVV90_13050	COG1104	cysteine desulfurase activity
NVV90_13060	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
NVV90_13065	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NVV90_13075	COG1522	sequence-specific DNA binding
NVV90_13080	COG1113	amino acid transport
NVV90_13090	COG0022	dehydrogenase e1 component
NVV90_13095	COG0508	dehydrogenase complex catalyzes the overall conversion of
NVV90_13115	COG1690	Belongs to the RtcB family
NVV90_13130	COG0477	Major facilitator Superfamily
NVV90_13145	COG1414	Transcriptional regulator
NVV90_13155	COG0419	ATPase involved in DNA repair
NVV90_13160	COG0420	3'-5' exonuclease activity
NVV90_13165	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NVV90_13175	COG2149	membrane
NVV90_13200	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NVV90_13205	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NVV90_13210	COG1234	tRNA 3'-trailer cleavage
NVV90_13215	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
NVV90_13225	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
NVV90_13235	COG1335	isochorismatase
NVV90_13255	COG0363	glucosamine-6-phosphate deaminase activity
NVV90_13270	COG1902	pentaerythritol trinitrate reductase activity
NVV90_13285	COG0628	permease
NVV90_13300	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
NVV90_13305	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NVV90_13315	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NVV90_13330	COG0355	proton-transporting ATP synthase activity, rotational mechanism
NVV90_13335	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NVV90_13340	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NVV90_13345	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NVV90_13350	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NVV90_13355	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NVV90_13360	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NVV90_13365	COG0356	it plays a direct role in the translocation of protons across the membrane
NVV90_13380	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NVV90_13395	COG0009	L-threonylcarbamoyladenylate synthase
NVV90_13400	COG2890	protein-(glutamine-N5) methyltransferase activity
NVV90_13405	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NVV90_13415	COG0083	homoserine kinase activity
NVV90_13420	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NVV90_13425	COG0460	homoserine dehydrogenase
NVV90_13435	COG0018	arginyl-trna synthetase
NVV90_13445	COG1477	protein flavinylation
NVV90_13485	COG1643	Atp-dependent helicase
NVV90_13495	COG2072	flavoprotein involved in K transport
NVV90_13505	COG2197	response regulator
NVV90_13510	COG0537	adenosine 5'-monophosphoramidase activity
NVV90_13515	COG1064	alcohol dehydrogenase
NVV90_13525	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NVV90_13540	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NVV90_13545	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
NVV90_13565	COG0508	dehydrogenase complex catalyzes the overall conversion of
NVV90_13565	COG0567	Dehydrogenase, E1 component
NVV90_13590	COG1595	DNA-templated transcription, initiation
NVV90_13600	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
NVV90_13610	COG0483	inositol monophosphate 1-phosphatase activity
NVV90_13615	COG2801	Transposase and inactivated derivatives
NVV90_13625	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NVV90_13650	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NVV90_13660	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NVV90_13675	COG2884	Cell division ATP-binding protein ftsE
NVV90_13680	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NVV90_13740	COG2246	polysaccharide biosynthetic process
NVV90_13755	COG1088	dTDP-glucose 4,6-dehydratase activity
NVV90_13760	COG1215	transferase activity, transferring glycosyl groups
NVV90_13775	COG1216	Glycosyl transferase, family 2
NVV90_13810	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NVV90_13830	COG1216	Glycosyl transferase, family 2
NVV90_13860	COG2902	Dehydrogenase
NVV90_13895	COG0653	protein targeting
NVV90_13900	COG3214	Protein conserved in bacteria
NVV90_13905	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NVV90_13915	COG5401	PFAM Sporulation and spore germination
NVV90_13920	COG5002	protein histidine kinase activity
NVV90_13945	COG0714	Associated with various cellular activities
NVV90_13980	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NVV90_13985	COG0601	transmembrane transport
NVV90_14005	COG0482	sulfurtransferase activity
NVV90_14035	COG0484	heat shock protein binding
NVV90_14040	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
NVV90_14065	COG3265	gluconokinase activity
NVV90_14075	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
NVV90_14085	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NVV90_14095	COG1842	Phage shock protein A
NVV90_14100	COG2188	Transcriptional regulator
NVV90_14110	COG1960	acyl-CoA dehydrogenase activity
NVV90_14115	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
NVV90_14120	COG2086	electron transfer activity
NVV90_14135	COG1615	UPF0182 protein
NVV90_14140	COG3480	Lon protease (S16) C-terminal proteolytic domain
NVV90_14160	COG2816	NAD+ diphosphatase activity
NVV90_14170	COG0210	DNA helicase
NVV90_14190	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NVV90_14195	COG0765	amino acid transport
NVV90_14200	COG1126	abc transporter atp-binding protein
NVV90_14205	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
NVV90_14215	COG0113	porphobilinogen synthase activity
NVV90_14225	COG0181	hydroxymethylbilane synthase activity
NVV90_14230	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
NVV90_14235	COG3253	May function as heme-dependent peroxidase
NVV90_14245	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NVV90_14250	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NVV90_14265	COG1309	transcriptional regulator
NVV90_14280	COG2154	pterin-4-alpha-carbinolamine dehydratase
NVV90_14285	COG2022	thiamine diphosphate biosynthetic process
NVV90_14295	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NVV90_14295	COG2022	thiamine diphosphate biosynthetic process
NVV90_14300	COG0352	thiamine-phosphate diphosphorylase activity
NVV90_14315	COG0513	Belongs to the DEAD box helicase family
NVV90_14330	COG2095	MarC family integral membrane protein
NVV90_14345	COG0006	proline dipeptidase activity
NVV90_14355	COG2239	Acts as a magnesium transporter
NVV90_14370	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NVV90_14380	COG1595	DNA-templated transcription, initiation
NVV90_14410	COG1126	abc transporter atp-binding protein
NVV90_14415	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NVV90_14420	COG0765	amino acid transport
NVV90_14425	COG0765	amino acid transport
NVV90_14430	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NVV90_14435	COG2171	N-acyltransferase activity
NVV90_14450	COG3226	Transcriptional regulator
NVV90_14455	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NVV90_14490	COG1217	gtp-binding protein TYPA
NVV90_14505	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NVV90_14510	COG0601	transmembrane transport
NVV90_14540	COG0012	GTP binding
NVV90_14545	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NVV90_14555	COG1570	exodeoxyribonuclease VII activity
NVV90_14560	COG1722	exodeoxyribonuclease VII activity
NVV90_14565	COG2326	polyphosphate kinase activity
NVV90_14585	COG1174	glycine betaine transport
NVV90_14595	COG1162	GTPase activity
NVV90_14620	COG2971	BadF BadG BcrA BcrD
NVV90_14630	COG0583	DNA-binding transcription factor activity
NVV90_14635	COG2814	Major facilitator Superfamily
NVV90_14640	COG0626	cystathionine gamma-synthase activity
NVV90_14665	COG0598	Magnesium transport protein CorA
NVV90_14675	COG1528	Iron-storage protein
NVV90_14680	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NVV90_14685	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NVV90_14700	COG2824	Alkylphosphonate utilization operon protein PhnA
NVV90_14725	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NVV90_14750	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NVV90_14750	COG0519	Catalyzes the synthesis of GMP from XMP
NVV90_14770	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NVV90_14775	COG0516	GMP reductase activity
NVV90_14780	COG1132	(ABC) transporter
NVV90_14795	COG0459	protein refolding
NVV90_14800	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NVV90_14815	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NVV90_14820	COG0257	Belongs to the bacterial ribosomal protein bL36 family
NVV90_14830	COG1472	Belongs to the glycosyl hydrolase 3 family
NVV90_14835	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
NVV90_14840	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NVV90_14845	COG0456	acetyltransferase
NVV90_14855	COG0802	atpase or kinase
NVV90_14860	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NVV90_14875	COG1486	melibiose metabolic process
NVV90_14885	COG0438	transferase activity, transferring glycosyl groups
NVV90_14890	COG2759	Belongs to the formate--tetrahydrofolate ligase family
NVV90_14925	COG0667	Aldo Keto reductase
NVV90_14940	COG0736	holo-[acyl-carrier-protein] synthase activity
NVV90_14950	COG1072	(Pantothenic acid kinase))
NVV90_14960	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NVV90_14965	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
NVV90_14970	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NVV90_15000	COG0489	protein tyrosine kinase activity
NVV90_15020	COG0101	tRNA pseudouridine synthase activity
NVV90_15025	COG0203	ribosomal protein L17
NVV90_15030	COG0202	RNA polymerase activity
NVV90_15035	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NVV90_15040	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NVV90_15045	COG0257	Belongs to the bacterial ribosomal protein bL36 family
NVV90_15050	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NVV90_15055	COG3191	aminopeptidase activity
NVV90_15075	COG0024	Methionine aminopeptidase
NVV90_15085	COG0318	PFAM AMP-dependent synthetase and ligase
NVV90_15090	COG2124	cytochrome p450
NVV90_15095	COG1215	transferase activity, transferring glycosyl groups
NVV90_15100	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NVV90_15105	COG0563	adenylate kinase activity
NVV90_15115	COG0200	Binds to the 23S rRNA
NVV90_15120	COG1841	ribosomal large subunit assembly
NVV90_15125	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NVV90_15135	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NVV90_15140	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NVV90_15145	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NVV90_15150	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NVV90_15155	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NVV90_15160	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NVV90_15170	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NVV90_15175	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NVV90_15180	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NVV90_15185	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NVV90_15190	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NVV90_15195	COG0089	rRNA binding
NVV90_15200	COG0088	Forms part of the polypeptide exit tunnel
NVV90_15205	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NVV90_15210	COG0051	transcription antitermination factor activity, RNA binding
NVV90_15230	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NVV90_15235	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NVV90_15240	COG0049	tRNA binding
NVV90_15245	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NVV90_15250	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NVV90_15255	COG0085	RNA polymerase activity
NVV90_15260	COG0183	Belongs to the thiolase family
NVV90_15265	COG0442	prolyl-tRNA aminoacylation
NVV90_15270	COG0222	ribosome binding
NVV90_15275	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NVV90_15290	COG0081	regulation of translation
NVV90_15295	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NVV90_15305	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NVV90_15315	COG0436	Aminotransferase
NVV90_15320	COG2197	response regulator
NVV90_15370	COG0404	The glycine cleavage system catalyzes the degradation of glycine
NVV90_15380	COG3485	protocatechuate 3,4-dioxygenase
NVV90_15390	COG0745	RESPONSE REGULATOR receiver
NVV90_15395	COG0456	acetyltransferase
NVV90_15400	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NVV90_15425	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NVV90_15430	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NVV90_15455	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NVV90_15470	COG0812	UDP-N-acetylmuramate dehydrogenase activity
NVV90_15480	COG2030	dehydratase
NVV90_15485	COG2030	dehydratase
NVV90_15495	COG0659	secondary active sulfate transmembrane transporter activity
NVV90_15520	COG0402	S-adenosylhomocysteine deaminase activity
NVV90_15535	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NVV90_15545	COG4989	oxidoreductase activity
NVV90_15550	COG0366	Alpha amylase catalytic
NVV90_15555	COG0395	ABC-type sugar transport system, permease component
NVV90_15560	COG1175	transmembrane transport
NVV90_15580	COG0702	epimerase
NVV90_15590	COG0366	Alpha amylase catalytic
NVV90_15605	COG0395	ABC-type sugar transport system, permease component
NVV90_15610	COG1175	transmembrane transport
NVV90_15620	COG1846	Transcriptional regulator
NVV90_15620	COG1940	carbohydrate kinase activity
NVV90_15635	COG1652	LysM domain
NVV90_15635	COG2823	Periplasmic or secreted lipoprotein
NVV90_15665	COG0754	glutathionylspermidine amidase activity
NVV90_15675	COG5650	phosphatidylinositol metabolic process
NVV90_15710	COG1051	belongs to the nudix hydrolase family
NVV90_15745	COG0318	PFAM AMP-dependent synthetase and ligase
NVV90_15755	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NVV90_15765	COG0673	inositol 2-dehydrogenase activity
NVV90_15770	COG1131	(ABC) transporter
NVV90_15795	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NVV90_15810	COG1666	GTP binding
NVV90_15815	COG0501	Belongs to the peptidase M48B family
NVV90_15840	COG0531	amino acid
NVV90_15870	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NVV90_15900	COG1012	belongs to the aldehyde dehydrogenase family
NVV90_15905	COG3835	regulator
NVV90_15910	COG2807	transmembrane transport
NVV90_15915	COG2186	Transcriptional regulator
NVV90_15920	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NVV90_15920	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NVV90_15930	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NVV90_15930	COG1648	precorrin-2 dehydrogenase activity
NVV90_15940	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NVV90_15950	COG1116	anion transmembrane transporter activity
NVV90_15960	COG2040	homocysteine
NVV90_15980	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NVV90_15990	COG2860	membrane
NVV90_16005	COG0142	geranyltranstransferase activity
NVV90_16010	COG0644	oxidoreductase
NVV90_16015	COG2226	methyltransferase
NVV90_16020	COG1169	isochorismate synthase
NVV90_16030	COG0765	amino acid transport
NVV90_16035	COG1126	abc transporter atp-binding protein
NVV90_16040	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
NVV90_16050	COG4948	Mandelate Racemase Muconate Lactonizing
NVV90_16065	COG1609	Transcriptional regulator
NVV90_16075	COG0395	ABC-type sugar transport system, permease component
NVV90_16080	COG1175	transmembrane transport
NVV90_16115	COG0508	dehydrogenase complex catalyzes the overall conversion of
NVV90_16120	COG0022	dehydrogenase e1 component
NVV90_16145	COG0489	protein tyrosine kinase activity
NVV90_16150	COG2755	lipolytic protein G-D-S-L family
NVV90_16150	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
NVV90_16155	COG0110	maltose O-acetyltransferase activity
NVV90_16200	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
NVV90_16225	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NVV90_16235	COG1024	Enoyl-CoA hydratase
NVV90_16240	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NVV90_16245	COG2151	metal-sulfur cluster biosynthetic enzyme
NVV90_16250	COG3396	Phenylacetate-CoA oxygenase
NVV90_16255	COG3460	Phenylacetate-CoA oxygenase
NVV90_16260	COG3396	Phenylacetate-CoA oxygenase
NVV90_16265	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NVV90_16270	COG1316	TRANSCRIPTIONal
NVV90_16285	COG1404	Belongs to the peptidase S8 family
NVV90_16295	COG2050	protein possibly involved in aromatic compounds catabolism
NVV90_16310	COG2318	DinB family
NVV90_16330	COG1012	belongs to the aldehyde dehydrogenase family
NVV90_16330	COG2030	dehydratase
NVV90_16340	COG1609	Transcriptional regulator
NVV90_16345	COG2182	Extracellular solute-binding protein
NVV90_16355	COG0395	ABC-type sugar transport system, permease component
NVV90_16365	COG0673	inositol 2-dehydrogenase activity
NVV90_16370	COG0673	inositol 2-dehydrogenase activity
NVV90_16410	COG2755	lipolytic protein G-D-S-L family
NVV90_16415	COG1250	3-hydroxyacyl-CoA dehydrogenase
NVV90_16420	COG1024	Enoyl-CoA hydratase
NVV90_16425	COG0183	Belongs to the thiolase family
NVV90_16450	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NVV90_16460	COG0488	(ABC) transporter
NVV90_16465	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NVV90_16470	COG1121	(ABC) transporter
NVV90_16495	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NVV90_16515	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NVV90_16525	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NVV90_16535	COG0785	Cytochrome C biogenesis protein
NVV90_16545	COG0406	alpha-ribazole phosphatase activity
NVV90_16565	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NVV90_16590	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NVV90_16595	COG1609	Transcriptional regulator
NVV90_16600	COG2186	Transcriptional regulator
NVV90_16610	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NVV90_16615	COG0640	Transcriptional regulator
NVV90_16625	COG0123	including yeast histone deacetylase and acetoin utilization protein
NVV90_16630	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NVV90_16635	COG0569	domain protein
NVV90_16640	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NVV90_16645	COG1082	Xylose isomerase domain protein TIM barrel
NVV90_16650	COG0248	Ppx GppA phosphatase
NVV90_16660	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NVV90_16660	COG1754	DNA topoisomerase type I activity
NVV90_16670	COG2890	protein-(glutamine-N5) methyltransferase activity
NVV90_16690	COG1054	Belongs to the UPF0176 family
NVV90_16700	COG1111	helicase
NVV90_16700	COG1205	dead DEAH box helicase
NVV90_16770	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NVV90_16775	COG1349	DNA-binding transcription factor activity
NVV90_16785	COG1609	Transcriptional regulator
NVV90_16795	COG1175	transmembrane transport
NVV90_16800	COG0395	ABC-type sugar transport system, permease component
NVV90_16815	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
NVV90_16845	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
NVV90_16850	COG1408	metallophosphoesterase
NVV90_16855	COG1132	(ABC) transporter
NVV90_16860	COG1132	(ABC) transporter
NVV90_16880	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
NVV90_16885	COG0151	Belongs to the GarS family
NVV90_16900	COG1301	dicarboxylic acid transport
NVV90_16905	COG1028	Short-chain dehydrogenase reductase Sdr
NVV90_16915	COG1953	Uracil, thiamine, allantoin
NVV90_16945	COG0454	-acetyltransferase
NVV90_16950	COG1529	Aldehyde oxidase and xanthine dehydrogenase
NVV90_16960	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
NVV90_16960	COG3608	succinylglutamate desuccinylase aspartoacylase
NVV90_16965	COG2252	PERMEase
NVV90_16970	COG0590	tRNA wobble adenosine to inosine editing
NVV90_16990	COG2233	PERMEase
NVV90_17000	COG1414	Transcriptional regulator
NVV90_17010	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
NVV90_17020	COG3257	ureidoglycine aminohydrolase activity
NVV90_17030	COG2318	DinB family
NVV90_17040	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NVV90_17045	COG0395	ABC-type sugar transport system, permease component
NVV90_17055	COG1653	transport
NVV90_17070	COG3119	arylsulfatase activity
NVV90_17075	COG1609	Transcriptional regulator
NVV90_17080	COG5492	domain, Protein
NVV90_17105	COG2271	Major facilitator Superfamily
NVV90_17115	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NVV90_17145	COG0028	Belongs to the TPP enzyme family
NVV90_17155	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NVV90_17160	COG1113	amino acid transport
NVV90_17185	COG2267	carboxylic ester hydrolase activity
NVV90_17215	COG1064	alcohol dehydrogenase
NVV90_17225	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NVV90_17225	COG4499	WXG100 protein secretion system (Wss), protein YukC
NVV90_17240	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NVV90_17265	COG0596	Alpha beta hydrolase
NVV90_17280	COG0395	ABC-type sugar transport system, permease component
NVV90_17285	COG1175	transmembrane transport
NVV90_17290	COG1653	transport
NVV90_17295	COG1609	Transcriptional regulator
NVV90_17330	COG2066	Belongs to the glutaminase family
NVV90_17345	COG1301	dicarboxylic acid transport
NVV90_17365	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NVV90_17395	COG0583	DNA-binding transcription factor activity
NVV90_17400	COG0583	DNA-binding transcription factor activity
NVV90_17405	COG0473	3-isopropylmalate dehydrogenase activity
NVV90_17405	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NVV90_17410	COG0473	3-isopropylmalate dehydrogenase activity
NVV90_17410	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NVV90_17430	COG0693	protein deglycase activity
NVV90_17480	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NVV90_17485	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NVV90_17505	COG3458	cephalosporin-C deacetylase activity
NVV90_17525	COG0395	ABC-type sugar transport system, permease component
NVV90_17530	COG1175	transmembrane transport
NVV90_17540	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
NVV90_17545	COG3250	beta-galactosidase activity
NVV90_17560	COG0174	glutamine synthetase
NVV90_17570	COG1028	Short-chain dehydrogenase reductase Sdr
NVV90_17605	COG3845	ABC transporter
NVV90_17615	COG1414	Transcriptional regulator
NVV90_17630	COG0477	Major facilitator Superfamily
NVV90_17640	COG0477	Major facilitator Superfamily
NVV90_17645	COG0646	methionine synthase
NVV90_17645	COG1410	methionine synthase
NVV90_17695	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NVV90_17710	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
NVV90_17765	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NVV90_17770	COG1024	Enoyl-CoA hydratase
NVV90_17825	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
NVV90_17830	COG1522	sequence-specific DNA binding
NVV90_17855	COG3622	Belongs to the hyi family
NVV90_17860	COG2084	Dehydrogenase
NVV90_17865	COG3960	tartronate-semialdehyde synthase activity
NVV90_17870	COG1929	Belongs to the glycerate kinase type-1 family
NVV90_17875	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NVV90_17880	COG0745	RESPONSE REGULATOR receiver
NVV90_17910	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
NVV90_17945	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
NVV90_17955	COG0765	amino acid transport
NVV90_17965	COG3608	succinylglutamate desuccinylase aspartoacylase
NVV90_17970	COG1802	Transcriptional regulator
NVV90_17990	COG0640	Transcriptional regulator
NVV90_18000	COG1175	transmembrane transport
NVV90_18010	COG3507	Belongs to the glycosyl hydrolase 43 family
NVV90_18020	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NVV90_18025	COG1609	Transcriptional regulator
NVV90_18040	COG0542	response to heat
NVV90_18070	COG3585	molybdate ion transport
NVV90_18105	COG3304	Inner membrane component domain
NVV90_18140	COG0135	phosphoribosylanthranilate isomerase activity
NVV90_18160	COG2076	Multidrug Resistance protein
NVV90_18170	COG1131	(ABC) transporter
NVV90_18180	COG0667	Aldo Keto reductase
NVV90_18205	COG0494	nUDIX hydrolase
NVV90_18225	COG1473	amidohydrolase
NVV90_18230	COG0477	Major facilitator Superfamily
NVV90_18235	COG2807	transmembrane transport
NVV90_18245	COG0220	tRNA (guanine-N7-)-methyltransferase activity
NVV90_18260	COG0129	dihydroxy-acid dehydratase activity
NVV90_18270	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NVV90_18315	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NVV90_18330	COG0745	RESPONSE REGULATOR receiver
NVV90_18355	COG2894	cell division
NVV90_18395	COG3226	Transcriptional regulator
NVV90_18400	COG4977	sequence-specific DNA binding
NVV90_18405	COG1012	belongs to the aldehyde dehydrogenase family
NVV90_18420	COG0402	S-adenosylhomocysteine deaminase activity
NVV90_18430	COG0765	amino acid transport
NVV90_18435	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NVV90_18440	COG0402	S-adenosylhomocysteine deaminase activity
NVV90_18450	COG0251	oxidation-reduction process
NVV90_18480	COG2814	Major facilitator Superfamily
NVV90_18485	COG0154	amidase activity
NVV90_18490	COG2957	Belongs to the agmatine deiminase family
NVV90_18520	COG0789	Transcriptional regulator
NVV90_18525	COG0484	heat shock protein binding
NVV90_18530	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NVV90_18535	COG0443	Heat shock 70 kDa protein
NVV90_18540	COG3739	integral membrane protein
NVV90_18625	COG0515	serine threonine protein kinase
NVV90_18625	COG2815	serine threonine protein kinase
NVV90_18635	COG0436	Aminotransferase
NVV90_18640	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NVV90_18640	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
NVV90_18645	COG0667	Aldo Keto reductase
NVV90_18650	COG1609	Transcriptional regulator
NVV90_18660	COG0531	amino acid
NVV90_18665	COG1280	lysine exporter protein (LysE YggA)
NVV90_18670	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NVV90_18675	COG3795	YCII-related domain
NVV90_18680	COG4941	Belongs to the sigma-70 factor family
NVV90_18700	COG1280	lysine exporter protein (LysE YggA)
NVV90_18705	COG1609	Transcriptional regulator
NVV90_18710	COG1957	nucleoside hydrolase
NVV90_18715	COG0477	Major facilitator Superfamily
NVV90_18720	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NVV90_18730	COG1131	(ABC) transporter
NVV90_18735	COG3559	Exporter of polyketide antibiotics
NVV90_18740	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NVV90_18750	COG1953	Uracil, thiamine, allantoin
NVV90_18770	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NVV90_18815	COG0277	FAD linked oxidase domain protein
NVV90_18825	COG2017	converts alpha-aldose to the beta-anomer
NVV90_18830	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NVV90_18835	COG4948	Mandelate Racemase Muconate Lactonizing
NVV90_18840	COG0395	ABC-type sugar transport system, permease component
NVV90_18845	COG1175	transmembrane transport
NVV90_18850	COG1653	transport
NVV90_18865	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NVV90_18875	COG2986	histidine ammonia-lyase
NVV90_18905	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
NVV90_18915	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NVV90_18935	COG1122	ATPase activity
NVV90_18940	COG4721	ABC-type cobalt transport system, permease component
NVV90_18955	COG1320	monovalent cation:proton antiporter activity
NVV90_18960	COG2212	antiporter activity
NVV90_18970	COG0651	ATP synthesis coupled electron transport
NVV90_18975	COG1006	Multisubunit Na H antiporter MnhC subunit
NVV90_18980	COG2111	Na H antiporter
NVV90_18980	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NVV90_18995	COG0475	glutathione-regulated potassium exporter activity
NVV90_19000	COG0717	Belongs to the dCTP deaminase family
NVV90_19040	COG0583	DNA-binding transcription factor activity
NVV90_19045	COG1309	transcriptional regulator
NVV90_19055	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
NVV90_19070	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NVV90_19080	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NVV90_19085	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NVV90_19095	COG2188	Transcriptional regulator
NVV90_19115	COG3842	ATPase activity
NVV90_19120	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NVV90_19140	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NVV90_19165	COG0765	amino acid transport
NVV90_19195	COG0673	inositol 2-dehydrogenase activity
NVV90_19200	COG1609	Transcriptional regulator
NVV90_19210	COG0433	COG0433 Predicted ATPase
NVV90_19230	COG0776	regulation of translation
NVV90_19275	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NVV90_19280	COG0267	Belongs to the bacterial ribosomal protein bL33 family
NVV90_19285	COG0227	Belongs to the bacterial ribosomal protein bL28 family
NVV90_19315	COG1120	ATPase activity
NVV90_19320	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NVV90_19325	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NVV90_19370	COG3012	SEC-C Motif Domain Protein
NVV90_19385	COG0667	Aldo Keto reductase
NVV90_19415	COG2409	Drug exporters of the RND superfamily
NVV90_19430	COG2186	Transcriptional regulator
NVV90_19440	COG1027	Aspartate ammonia-lyase
NVV90_19475	COG4948	Mandelate Racemase Muconate Lactonizing
NVV90_19485	COG1028	Short-chain dehydrogenase reductase Sdr
NVV90_19510	COG2515	1-aminocyclopropane-1-carboxylate deaminase
NVV90_19525	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NVV90_19530	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NVV90_19555	COG1280	lysine exporter protein (LysE YggA)
NVV90_19570	COG0640	Transcriptional regulator
NVV90_19585	COG2197	response regulator
NVV90_19590	COG4585	Histidine kinase
NVV90_19605	COG1957	nucleoside hydrolase
NVV90_19615	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NVV90_19625	COG1309	transcriptional regulator
NVV90_19630	COG2211	Major facilitator Superfamily
NVV90_19635	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NVV90_19640	COG0477	Major facilitator Superfamily
NVV90_19645	COG2986	histidine ammonia-lyase
NVV90_19650	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NVV90_19680	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NVV90_19690	COG0477	Major facilitator Superfamily
NVV90_19720	COG1113	amino acid transport
NVV90_19725	COG0246	Mannitol dehydrogenase
NVV90_19730	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
NVV90_19730	COG2213	PTS system mannitol-specific
NVV90_19740	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NVV90_19745	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NVV90_19755	COG1621	beta-fructofuranosidase activity
NVV90_19760	COG4608	Belongs to the ABC transporter superfamily
NVV90_19765	COG0444	Belongs to the ABC transporter superfamily
NVV90_19770	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NVV90_19775	COG0601	transmembrane transport
NVV90_19790	COG1309	transcriptional regulator
NVV90_19810	COG2199	diguanylate cyclase activity
NVV90_19810	COG2200	EAL domain
NVV90_19840	COG0686	Belongs to the AlaDH PNT family
NVV90_19850	COG1595	DNA-templated transcription, initiation
NVV90_19865	COG0673	inositol 2-dehydrogenase activity
NVV90_19890	COG1309	transcriptional regulator
NVV90_19895	COG0431	NADPH-dependent FMN reductase
NVV90_19925	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NVV90_19930	COG0589	response to stress
NVV90_19945	COG0508	dehydrogenase complex catalyzes the overall conversion of
NVV90_19950	COG0022	dehydrogenase e1 component
NVV90_19960	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NVV90_19965	COG1950	PFAM Membrane protein of
NVV90_19985	COG0406	alpha-ribazole phosphatase activity
NVV90_20000	COG1607	acyl-coa hydrolase
NVV90_20005	COG4221	oxidoreductase activity
NVV90_20010	COG0477	Major facilitator Superfamily
NVV90_20015	COG1984	allophanate hydrolase subunit 2
NVV90_20020	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
NVV90_20025	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
NVV90_20030	COG1177	transmembrane transport
NVV90_20035	COG1176	ABC-type spermidine putrescine transport system, permease component I
NVV90_20040	COG3842	ATPase activity
NVV90_20050	COG0583	DNA-binding transcription factor activity
NVV90_20060	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NVV90_20065	COG0436	Aminotransferase
NVV90_20085	COG3971	2-oxopent-4-enoate hydratase activity
NVV90_20100	COG1802	Transcriptional regulator
NVV90_20105	COG0179	Fumarylacetoacetate (FAA) hydrolase
NVV90_20160	COG1609	Transcriptional regulator
NVV90_20165	COG1653	transport
NVV90_20175	COG0395	ABC-type sugar transport system, permease component
NVV90_20180	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NVV90_20190	COG3706	GGDEF domain
NVV90_20205	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
NVV90_20210	COG1012	belongs to the aldehyde dehydrogenase family
NVV90_20220	COG1970	mechanosensitive ion channel activity
NVV90_20240	COG2271	Major facilitator Superfamily
NVV90_20245	COG0477	Major facilitator Superfamily
NVV90_20250	COG0154	amidase activity
NVV90_20255	COG1802	Transcriptional regulator
NVV90_20290	COG1653	transport
NVV90_20295	COG1175	transmembrane transport
NVV90_20300	COG0395	ABC-type sugar transport system, permease component
NVV90_20305	COG1609	Transcriptional regulator
NVV90_20310	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NVV90_20355	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NVV90_20375	COG3485	protocatechuate 3,4-dioxygenase
NVV90_20380	COG1082	Xylose isomerase domain protein TIM barrel
NVV90_20380	COG3185	4-Hydroxyphenylpyruvate dioxygenase
NVV90_20385	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NVV90_20390	COG1414	Transcriptional regulator
NVV90_20395	COG0477	Major facilitator Superfamily
NVV90_20410	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
NVV90_20440	COG1321	iron dependent repressor
NVV90_20455	COG0596	Alpha beta hydrolase
NVV90_20460	COG1937	Protein conserved in bacteria
NVV90_20515	COG2259	Doxx family
NVV90_20525	COG1607	acyl-coa hydrolase
NVV90_20535	COG0305	Participates in initiation and elongation during chromosome replication
NVV90_20575	COG0359	binds to the 23S rRNA
NVV90_20580	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NVV90_20590	COG0360	Binds together with S18 to 16S ribosomal RNA
NVV90_20620	COG1113	amino acid transport
NVV90_20635	COG2244	polysaccharide biosynthetic process
NVV90_20645	COG1120	ATPase activity
NVV90_20680	COG1362	aminopeptidase activity
NVV90_20690	COG2197	response regulator
NVV90_20695	COG4585	Histidine kinase
NVV90_20700	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NVV90_20710	COG1131	(ABC) transporter
NVV90_20725	COG0738	Major facilitator superfamily
NVV90_20730	COG3226	Transcriptional regulator
NVV90_20750	COG0154	amidase activity
NVV90_20755	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NVV90_20760	COG0477	Major facilitator Superfamily
NVV90_20765	COG2610	gluconate transmembrane transporter activity
NVV90_20775	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
NVV90_20790	COG1414	Transcriptional regulator
NVV90_20800	COG0583	DNA-binding transcription factor activity
NVV90_20815	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NVV90_20820	COG0768	penicillin binding
NVV90_20825	COG1501	Belongs to the glycosyl hydrolase 31 family
NVV90_20830	COG2197	response regulator
NVV90_20835	COG4585	Histidine kinase
NVV90_20845	COG1136	(ABC) transporter
NVV90_20845	COG4591	ABC-type transport system involved in lipoprotein release permease component
NVV90_20850	COG1733	regulation of RNA biosynthetic process
NVV90_20855	COG2910	NAD(P)H-binding
NVV90_20875	COG0406	alpha-ribazole phosphatase activity
NVV90_20880	COG0617	tRNA 3'-terminal CCA addition
NVV90_20900	COG0492	ferredoxin-NADP+ reductase activity
NVV90_20905	COG3118	belongs to the thioredoxin family
NVV90_20910	COG1475	DNA binding
NVV90_20915	COG1192	Involved in chromosome partitioning
NVV90_20920	COG0357	Ribosomal RNA small subunit methyltransferase G
NVV90_20930	COG0706	membrane insertase activity
NVV90_20935	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
NVV90_20940	COG0594	ribonuclease P activity
NVV90_20945	COG0230	Belongs to the bacterial ribosomal protein bL34 family