locus-tag	class	description
LFT48_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LFT48_00010	COG0592	DNA-directed DNA polymerase activity
LFT48_00015	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
LFT48_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LFT48_00025	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
LFT48_00030	COG0187	DNA topoisomerase II activity
LFT48_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LFT48_00040	COG3266	domain, Protein
LFT48_00065	COG1215	transferase activity, transferring glycosyl groups
LFT48_00080	COG0457	Tetratricopeptide repeat
LFT48_00080	COG0705	Rhomboid family
LFT48_00090	COG2818	Glycosylase
LFT48_00100	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LFT48_00105	COG1595	DNA-templated transcription, initiation
LFT48_00120	COG3764	Sortase (surface protein transpeptidase)
LFT48_00130	COG0515	serine threonine protein kinase
LFT48_00130	COG2815	serine threonine protein kinase
LFT48_00135	COG0515	serine threonine protein kinase
LFT48_00140	COG0768	penicillin binding
LFT48_00155	COG1716	ATPase activity
LFT48_00160	COG1716	ATPase activity
LFT48_00170	COG2188	Transcriptional regulator
LFT48_00215	COG0346	lactoylglutathione lyase activity
LFT48_00230	COG2186	Transcriptional regulator
LFT48_00235	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
LFT48_00240	COG0477	Major facilitator Superfamily
LFT48_00245	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
LFT48_00250	COG4770	biotin carboxylase activity
LFT48_00255	COG0277	FAD linked oxidase domain protein
LFT48_00265	COG0385	Bile acid
LFT48_00270	COG0659	secondary active sulfate transmembrane transporter activity
LFT48_00290	COG0435	Glutathione S-transferase
LFT48_00295	COG0561	phosphatase activity
LFT48_00315	COG0584	glycerophosphoryl diester phosphodiesterase
LFT48_00320	COG3250	beta-galactosidase activity
LFT48_00325	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LFT48_00330	COG1929	Belongs to the glycerate kinase type-1 family
LFT48_00360	COG1937	Protein conserved in bacteria
LFT48_00380	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LFT48_00385	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LFT48_00395	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LFT48_00445	COG0693	protein deglycase activity
LFT48_00455	COG3655	Transcriptional regulator
LFT48_00470	COG4152	abc transporter atp-binding protein
LFT48_00485	COG2723	6-phospho-beta-galactosidase activity
LFT48_00490	COG0395	ABC-type sugar transport system, permease component
LFT48_00520	COG2233	PERMEase
LFT48_00530	COG0778	Nitroreductase
LFT48_00560	COG3104	oligopeptide transport
LFT48_00570	COG3340	Belongs to the peptidase S51 family
LFT48_00575	COG0425	Belongs to the sulfur carrier protein TusA family
LFT48_00575	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LFT48_00580	COG0077	Prephenate dehydratase
LFT48_00590	COG1597	lipid kinase activity
LFT48_00595	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LFT48_00610	COG0561	phosphatase activity
LFT48_00620	COG1191	sigma factor activity
LFT48_00630	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
LFT48_00635	COG0859	PFAM glycosyl transferase family 9
LFT48_00645	COG0438	transferase activity, transferring glycosyl groups
LFT48_00650	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
LFT48_00655	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
LFT48_00655	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
LFT48_00670	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
LFT48_00670	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
LFT48_00735	COG2027	D-alanyl-D-alanine carboxypeptidase
LFT48_00745	COG0037	tRNA processing
LFT48_00765	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LFT48_00770	COG0302	gtp cyclohydrolase
LFT48_00780	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LFT48_00810	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LFT48_00815	COG2814	Major facilitator Superfamily
LFT48_00860	COG1028	Short-chain dehydrogenase reductase Sdr
LFT48_00880	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
LFT48_00905	COG1506	peptidase
LFT48_00905	COG0823	Involved in the tonB-independent uptake of proteins
LFT48_00910	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
LFT48_00925	COG2376	Dihydroxyacetone kinase
LFT48_00930	COG1461	Dihydroxyacetone kinase
LFT48_00935	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
LFT48_00940	COG3237	CsbD-like
LFT48_00965	COG0300	oxidoreductase activity
LFT48_00985	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LFT48_00990	COG1028	Short-chain dehydrogenase reductase Sdr
LFT48_01030	COG0154	amidase activity
LFT48_01045	COG5002	protein histidine kinase activity
LFT48_01055	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
LFT48_01075	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LFT48_01090	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LFT48_01120	COG2226	methyltransferase
LFT48_01160	COG1609	Transcriptional regulator
LFT48_01180	COG0831	urea catabolic process
LFT48_01185	COG0832	Belongs to the urease beta subunit family
LFT48_01190	COG0804	urea catabolic process
LFT48_01195	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
LFT48_01200	COG0830	nickel cation binding
LFT48_01205	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
LFT48_01210	COG0829	nickel cation binding
LFT48_01215	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
LFT48_01265	COG0656	L-ascorbic acid biosynthetic process
LFT48_01275	COG0667	Aldo Keto reductase
LFT48_01280	COG0656	L-ascorbic acid biosynthetic process
LFT48_01290	COG3360	Dodecin
LFT48_01295	COG1028	Short-chain dehydrogenase reductase Sdr
LFT48_01310	COG4677	pectinesterase activity
LFT48_01315	COG0395	ABC-type sugar transport system, permease component
LFT48_01320	COG1175	transmembrane transport
LFT48_01340	COG1609	Transcriptional regulator
LFT48_01345	COG0028	Belongs to the TPP enzyme family
LFT48_01350	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
LFT48_01355	COG1233	COG1233 Phytoene dehydrogenase and related
LFT48_01360	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LFT48_01380	COG3177	Filamentation induced by cAMP protein fic
LFT48_01385	COG2186	Transcriptional regulator
LFT48_01400	COG2084	Dehydrogenase
LFT48_01405	COG2610	gluconate transmembrane transporter activity
LFT48_01455	COG0076	glutamate decarboxylase activity
LFT48_01460	COG3486	L-lysine 6-monooxygenase (NADPH) activity
LFT48_01490	COG1028	Short-chain dehydrogenase reductase Sdr
LFT48_01520	COG0346	lactoylglutathione lyase activity
LFT48_01525	COG0697	spore germination
LFT48_01530	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LFT48_01545	COG0477	Major facilitator Superfamily
LFT48_01560	COG3285	dna ligase
LFT48_01560	COG1793	dna ligase
LFT48_01565	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
LFT48_01610	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LFT48_01610	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LFT48_01610	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LFT48_01615	COG1105	Belongs to the carbohydrate kinase PfkB family
LFT48_01620	COG1349	DNA-binding transcription factor activity
LFT48_01640	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
LFT48_01665	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LFT48_01685	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LFT48_01690	COG0765	amino acid transport
LFT48_01695	COG1126	abc transporter atp-binding protein
LFT48_01700	COG0251	oxidation-reduction process
LFT48_01730	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LFT48_01750	COG1846	Transcriptional regulator
LFT48_01765	COG1233	COG1233 Phytoene dehydrogenase and related
LFT48_01775	COG0142	geranyltranstransferase activity
LFT48_01780	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
LFT48_01795	COG5001	Diguanylate cyclase
LFT48_01795	COG3300	MHYT domain
LFT48_01825	COG0129	dihydroxy-acid dehydratase activity
LFT48_01840	COG2197	response regulator
LFT48_01865	COG2066	Belongs to the glutaminase family
LFT48_01880	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
LFT48_01885	COG1984	allophanate hydrolase subunit 2
LFT48_01910	COG2733	membrane
LFT48_01950	COG4122	O-methyltransferase activity
LFT48_01985	COG1132	(ABC) transporter
LFT48_01995	COG2207	Transcriptional regulator
LFT48_02010	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LFT48_02015	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LFT48_02020	COG1120	ATPase activity
LFT48_02035	COG1028	Short-chain dehydrogenase reductase Sdr
LFT48_02040	COG1733	regulation of RNA biosynthetic process
LFT48_02045	COG0702	epimerase
LFT48_02080	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
LFT48_02110	COG0010	Belongs to the arginase family
LFT48_02115	COG2252	PERMEase
LFT48_02155	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LFT48_02185	COG1309	transcriptional regulator
LFT48_02205	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
LFT48_02210	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LFT48_02215	COG1609	Transcriptional regulator
LFT48_02225	COG1175	transmembrane transport
LFT48_02230	COG0395	ABC-type sugar transport system, permease component
LFT48_02305	COG1653	transport
LFT48_02310	COG1175	transmembrane transport
LFT48_02315	COG0395	ABC-type sugar transport system, permease component
LFT48_02320	COG1609	Transcriptional regulator
LFT48_02340	COG2197	response regulator
LFT48_02345	COG4585	Histidine kinase
LFT48_02360	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LFT48_02370	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LFT48_02395	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LFT48_02405	COG0303	'Molybdopterin
LFT48_02410	COG1063	alcohol dehydrogenase
LFT48_02420	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LFT48_02425	COG3404	Formiminotransferase-cyclodeaminase
LFT48_02440	COG1802	Transcriptional regulator
LFT48_02445	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
LFT48_02455	COG0583	DNA-binding transcription factor activity
LFT48_02480	COG0415	Belongs to the DNA photolyase family
LFT48_02495	COG1024	Enoyl-CoA hydratase
LFT48_02550	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LFT48_02555	COG1960	acyl-CoA dehydrogenase activity
LFT48_02570	COG1012	belongs to the aldehyde dehydrogenase family
LFT48_02605	COG0789	Transcriptional regulator
LFT48_02615	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
LFT48_02620	COG1609	Transcriptional regulator
LFT48_02645	COG0444	Belongs to the ABC transporter superfamily
LFT48_02660	COG0673	inositol 2-dehydrogenase activity
LFT48_02665	COG1609	Transcriptional regulator
LFT48_02670	COG1904	glucuronate isomerase
LFT48_02675	COG0246	Mannitol dehydrogenase
LFT48_02680	COG4948	Mandelate Racemase Muconate Lactonizing
LFT48_02690	COG4213	ABC transporter substrate-binding protein
LFT48_02695	COG1129	ABC transporter
LFT48_02700	COG4214	carbohydrate transport
LFT48_02705	COG1609	Transcriptional regulator
LFT48_02710	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LFT48_02735	COG1136	(ABC) transporter
LFT48_02750	COG0357	Ribosomal RNA small subunit methyltransferase G
LFT48_02750	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LFT48_02795	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LFT48_02810	COG2814	Major facilitator Superfamily
LFT48_02830	COG1620	l-lactate permease
LFT48_02835	COG0247	lactate metabolic process
LFT48_02835	COG0277	FAD linked oxidase domain protein
LFT48_02840	COG1053	succinate dehydrogenase
LFT48_02845	COG0583	DNA-binding transcription factor activity
LFT48_02850	COG0039	L-malate dehydrogenase activity
LFT48_02855	COG2072	flavoprotein involved in K transport
LFT48_02880	COG0583	DNA-binding transcription factor activity
LFT48_02885	COG0477	Major facilitator Superfamily
LFT48_02905	COG1012	belongs to the aldehyde dehydrogenase family
LFT48_02915	COG0477	Major facilitator Superfamily
LFT48_02935	COG4932	domain protein
LFT48_02935	COG5492	domain, Protein
LFT48_02950	COG1609	Transcriptional regulator
LFT48_02960	COG0765	amino acid transport
LFT48_02965	COG1126	abc transporter atp-binding protein
LFT48_02970	COG0673	inositol 2-dehydrogenase activity
LFT48_03035	COG1832	CoA-binding protein
LFT48_03045	COG2315	Protein conserved in bacteria
LFT48_03055	COG1653	transport
LFT48_03060	COG1175	transmembrane transport
LFT48_03065	COG0395	ABC-type sugar transport system, permease component
LFT48_03095	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LFT48_03100	COG0047	phosphoribosylformylglycinamidine synthase activity
LFT48_03120	COG3546	catalase activity
LFT48_03125	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LFT48_03155	COG1846	Transcriptional regulator
LFT48_03170	COG5416	Lipopolysaccharide assembly protein A domain
LFT48_03185	COG2814	Major facilitator Superfamily
LFT48_03210	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LFT48_03225	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LFT48_03240	COG1012	belongs to the aldehyde dehydrogenase family
LFT48_03255	COG1846	Transcriptional regulator
LFT48_03260	COG0739	heme binding
LFT48_03260	COG1196	nuclear chromosome segregation
LFT48_03260	COG0741	lytic transglycosylase activity
LFT48_03265	COG0386	Belongs to the glutathione peroxidase family
LFT48_03270	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
LFT48_03310	COG1309	transcriptional regulator
LFT48_03315	COG1609	Transcriptional regulator
LFT48_03325	COG1175	transmembrane transport
LFT48_03330	COG0395	ABC-type sugar transport system, permease component
LFT48_03345	COG0438	transferase activity, transferring glycosyl groups
LFT48_03360	COG1621	beta-fructofuranosidase activity
LFT48_03365	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LFT48_03380	COG0395	ABC-type sugar transport system, permease component
LFT48_03390	COG1653	transport
LFT48_03400	COG0589	response to stress
LFT48_03420	COG3290	protein histidine kinase activity
LFT48_03425	COG4565	transcriptional regulatory protein
LFT48_03440	COG4702	Belongs to the UPF0303 family
LFT48_03460	COG0673	inositol 2-dehydrogenase activity
LFT48_03470	COG1940	carbohydrate kinase activity
LFT48_03470	COG1846	Transcriptional regulator
LFT48_03480	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
LFT48_03490	COG1476	TRANSCRIPTIONal
LFT48_03500	COG1309	transcriptional regulator
LFT48_03510	COG0351	phosphomethylpyrimidine kinase
LFT48_03520	COG0642	Histidine kinase
LFT48_03525	COG0745	RESPONSE REGULATOR receiver
LFT48_03530	COG0477	Major facilitator Superfamily
LFT48_03545	COG1090	epimerase
LFT48_03550	COG1309	transcriptional regulator
LFT48_03565	COG0343	queuine tRNA-ribosyltransferase activity
LFT48_03605	COG1960	acyl-CoA dehydrogenase activity
LFT48_03635	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
LFT48_03645	COG0586	Pfam SNARE associated Golgi protein
LFT48_03665	COG0564	pseudouridine synthase activity
LFT48_03695	COG2364	Membrane
LFT48_03710	COG1215	transferase activity, transferring glycosyl groups
LFT48_03720	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LFT48_03725	COG1201	RNA secondary structure unwinding
LFT48_03805	COG0438	transferase activity, transferring glycosyl groups
LFT48_03815	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LFT48_03840	COG2205	protein histidine kinase activity
LFT48_03845	COG0745	RESPONSE REGULATOR receiver
LFT48_03855	COG2062	phosphohistidine phosphatase, SixA
LFT48_03865	COG0583	DNA-binding transcription factor activity
LFT48_03870	COG0697	spore germination
LFT48_03885	COG1574	metal-dependent hydrolase with the TIM-barrel fold
LFT48_03895	COG0601	transmembrane transport
LFT48_03905	COG4172	Belongs to the ABC transporter superfamily
LFT48_03910	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LFT48_03920	COG1309	transcriptional regulator
LFT48_03925	COG1511	domain protein
LFT48_03945	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
LFT48_03950	COG1940	carbohydrate kinase activity
LFT48_03960	COG4608	Belongs to the ABC transporter superfamily
LFT48_03965	COG0444	Belongs to the ABC transporter superfamily
LFT48_03970	COG0601	transmembrane transport
LFT48_03975	COG0747	negative chemotaxis
LFT48_03990	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
LFT48_03995	COG1017	nitric oxide dioxygenase activity
LFT48_03995	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LFT48_04015	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LFT48_04020	COG0514	ATP-dependent DNA helicase (RecQ)
LFT48_04025	COG0477	Major facilitator Superfamily
LFT48_04035	COG1505	serine-type exopeptidase activity
LFT48_04045	COG1113	amino acid transport
LFT48_04065	COG1028	Short-chain dehydrogenase reductase Sdr
LFT48_04065	COG3321	synthase
LFT48_04065	COG0604	alcohol dehydrogenase
LFT48_04075	COG1966	Carbon starvation protein
LFT48_04095	COG0656	L-ascorbic acid biosynthetic process
LFT48_04125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LFT48_04130	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LFT48_04150	COG0588	phosphoglycerate mutase activity
LFT48_04180	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
LFT48_04190	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
LFT48_04200	COG0215	cysteine-tRNA ligase activity
LFT48_04225	COG2732	(Barnase) inhibitor
LFT48_04235	COG0366	Alpha amylase catalytic
LFT48_04245	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LFT48_04275	COG1609	Transcriptional regulator
LFT48_04280	COG0366	Alpha amylase catalytic
LFT48_04295	COG3833	ABC-type maltose transport systems, permease component
LFT48_04300	COG0366	Alpha amylase catalytic
LFT48_04305	COG0277	FAD linked oxidase domain protein
LFT48_04340	COG3842	ATPase activity
LFT48_04395	COG1278	Cold shock
LFT48_04420	COG1309	transcriptional regulator
LFT48_04435	COG0586	Pfam SNARE associated Golgi protein
LFT48_04450	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LFT48_04565	COG1674	ftsk spoiiie
LFT48_04600	COG1028	Short-chain dehydrogenase reductase Sdr
LFT48_04610	COG1960	acyl-CoA dehydrogenase activity
LFT48_04635	COG0579	oxidoreductase
LFT48_04660	COG2957	Belongs to the agmatine deiminase family
LFT48_04700	COG0477	Major facilitator Superfamily
LFT48_04710	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LFT48_04710	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LFT48_04715	COG0404	The glycine cleavage system catalyzes the degradation of glycine
LFT48_04720	COG0509	glycine decarboxylation via glycine cleavage system
LFT48_04730	COG3591	Belongs to the peptidase S1B family
LFT48_04730	COG1864	DNA RNA non-specific endonuclease
LFT48_04775	COG0459	protein refolding
LFT48_04780	COG0328	RNA-DNA hybrid ribonuclease activity
LFT48_04790	COG2205	protein histidine kinase activity
LFT48_04795	COG0745	RESPONSE REGULATOR receiver
LFT48_04805	COG0583	DNA-binding transcription factor activity
LFT48_04815	COG2132	Multicopper oxidase
LFT48_04840	COG1278	Cold shock
LFT48_04850	COG2814	Major facilitator Superfamily
LFT48_04865	COG0739	heme binding
LFT48_04870	COG3103	Sh3 type 3 domain protein
LFT48_04870	COG0791	NLP P60 protein
LFT48_04870	COG1388	LysM domain
LFT48_04885	COG0746	molybdenum cofactor guanylyltransferase activity
LFT48_04900	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LFT48_04920	COG1126	abc transporter atp-binding protein
LFT48_04925	COG0765	amino acid transport
LFT48_04930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LFT48_04945	COG0488	(ABC) transporter
LFT48_04950	COG1132	(ABC) transporter
LFT48_04955	COG0494	nUDIX hydrolase
LFT48_04980	COG0483	inositol monophosphate 1-phosphatase activity
LFT48_05045	COG0045	succinate-CoA ligase (ADP-forming) activity
LFT48_05090	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LFT48_05095	COG1396	sequence-specific DNA binding
LFT48_05115	COG0028	Belongs to the TPP enzyme family
LFT48_05155	COG0457	Tetratricopeptide repeat
LFT48_05165	COG1401	restriction endodeoxyribonuclease activity
LFT48_05180	COG5002	protein histidine kinase activity
LFT48_05195	COG1012	belongs to the aldehyde dehydrogenase family
LFT48_05210	COG1024	Enoyl-CoA hydratase
LFT48_05215	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LFT48_05225	COG0477	Major facilitator Superfamily
LFT48_05230	COG1396	sequence-specific DNA binding
LFT48_05250	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
LFT48_05260	COG3237	CsbD-like
LFT48_05265	COG1028	Short-chain dehydrogenase reductase Sdr
LFT48_05290	COG1902	pentaerythritol trinitrate reductase activity
LFT48_05305	COG2376	Dihydroxyacetone kinase
LFT48_05310	COG0698	ribose 5-phosphate isomerase
LFT48_05315	COG1250	3-hydroxyacyl-CoA dehydrogenase
LFT48_05320	COG1028	Short-chain dehydrogenase reductase Sdr
LFT48_05325	COG2271	Major facilitator Superfamily
LFT48_05330	COG0149	triose-phosphate isomerase activity
LFT48_05365	COG1984	allophanate hydrolase subunit 2
LFT48_05380	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LFT48_05395	COG1254	Belongs to the acylphosphatase family
LFT48_05400	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LFT48_05405	COG2186	Transcriptional regulator
LFT48_05410	COG0477	Major facilitator Superfamily
LFT48_05420	COG0640	Transcriptional regulator
LFT48_05425	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LFT48_05470	COG2365	Tyrosine phosphatase family
LFT48_05475	COG3639	organic phosphonate transmembrane transporter activity
LFT48_05480	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
LFT48_05490	COG0477	Major facilitator Superfamily
LFT48_05530	COG0577	efflux transmembrane transporter activity
LFT48_05530	COG1136	(ABC) transporter
LFT48_05595	COG1278	Cold shock
LFT48_05615	COG3593	DNA synthesis involved in DNA repair
LFT48_05625	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LFT48_05630	COG0438	transferase activity, transferring glycosyl groups
LFT48_05640	COG0789	Transcriptional regulator
LFT48_05650	COG0484	heat shock protein binding
LFT48_05675	COG2814	Major facilitator Superfamily
LFT48_05680	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
LFT48_05695	COG0138	bifunctional purine biosynthesis protein purh
LFT48_05705	COG2838	Isocitrate dehydrogenase
LFT48_05715	COG3639	organic phosphonate transmembrane transporter activity
LFT48_05720	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
LFT48_05735	COG2188	Transcriptional regulator
LFT48_05750	COG0673	inositol 2-dehydrogenase activity
LFT48_05755	COG1136	(ABC) transporter
LFT48_05765	COG4213	ABC transporter substrate-binding protein
LFT48_05770	COG1172	Belongs to the binding-protein-dependent transport system permease family
LFT48_05775	COG1129	ABC transporter
LFT48_05785	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LFT48_05795	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LFT48_05800	COG0531	amino acid
LFT48_05830	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LFT48_05835	COG4585	Histidine kinase
LFT48_05840	COG2197	response regulator
LFT48_05850	COG1131	(ABC) transporter
LFT48_05875	COG0180	Tryptophanyl-tRNA synthetase
LFT48_05910	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LFT48_05925	COG2009	succinate dehydrogenase
LFT48_05935	COG1473	amidohydrolase
LFT48_05935	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
LFT48_05940	COG1846	Transcriptional regulator
LFT48_05945	COG1764	response to oxidative stress
LFT48_05950	COG2130	NADP-dependent
LFT48_05955	COG1744	ABC transporter substrate-binding protein PnrA-like
LFT48_05960	COG3845	ABC transporter
LFT48_05965	COG4603	Belongs to the binding-protein-dependent transport system permease family
LFT48_05970	COG1079	Belongs to the binding-protein-dependent transport system permease family
LFT48_05985	COG0586	Pfam SNARE associated Golgi protein
LFT48_05990	COG0586	Pfam SNARE associated Golgi protein
LFT48_05995	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LFT48_06000	COG3956	TIGRFAM MazG family protein
LFT48_06005	COG0148	phosphopyruvate hydratase activity
LFT48_06030	COG1252	NADH dehydrogenase
LFT48_06050	COG1597	lipid kinase activity
LFT48_06070	COG0559	Belongs to the binding-protein-dependent transport system permease family
LFT48_06080	COG0183	Belongs to the thiolase family
LFT48_06085	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LFT48_06095	COG2017	converts alpha-aldose to the beta-anomer
LFT48_06105	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LFT48_06115	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LFT48_06125	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LFT48_06140	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LFT48_06145	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
LFT48_06185	COG0114	fumarate hydratase activity
LFT48_06190	COG0288	reversible hydration of carbon dioxide
LFT48_06200	COG1494	fructose-1,6-bisphosphatase
LFT48_06210	COG1482	cell wall glycoprotein biosynthetic process
LFT48_06220	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LFT48_06270	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
LFT48_06275	COG1376	ErfK ybiS ycfS ynhG family protein
LFT48_06285	COG1357	PFAM Pentapeptide repeats (8 copies)
LFT48_06335	COG0714	Associated with various cellular activities
LFT48_06340	COG0084	hydrolase, TatD family'
LFT48_06345	COG3583	domain protein
LFT48_06350	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LFT48_06355	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LFT48_06360	COG0488	(ABC) transporter
LFT48_06370	COG1309	transcriptional regulator
LFT48_06380	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LFT48_06385	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LFT48_06390	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
LFT48_06395	COG0193	aminoacyl-tRNA hydrolase activity
LFT48_06420	COG0822	iron-sulfur transferase activity
LFT48_06425	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LFT48_06440	COG0702	epimerase
LFT48_06450	COG1988	membrane-bound metal-dependent
LFT48_06465	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LFT48_06470	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LFT48_06470	COG2146	nitrite reductase [NAD(P)H] activity
LFT48_06475	COG1028	Short-chain dehydrogenase reductase Sdr
LFT48_06505	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LFT48_06520	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LFT48_06520	COG2146	nitrite reductase [NAD(P)H] activity
LFT48_06530	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LFT48_06535	COG1621	beta-fructofuranosidase activity
LFT48_06560	COG0243	molybdopterin cofactor binding
LFT48_06565	COG2223	nitrite transmembrane transporter activity
LFT48_06570	COG0477	Major facilitator Superfamily
LFT48_06575	COG4770	biotin carboxylase activity
LFT48_06580	COG0424	maF-like protein
LFT48_06585	COG2409	Drug exporters of the RND superfamily
LFT48_06590	COG1309	transcriptional regulator
LFT48_06595	COG0393	Putative heavy-metal-binding
LFT48_06600	COG1823	symporter activity
LFT48_06630	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LFT48_06635	COG1028	Short-chain dehydrogenase reductase Sdr
LFT48_06640	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
LFT48_06640	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
LFT48_06665	COG0714	Associated with various cellular activities
LFT48_06685	COG0631	protein serine/threonine phosphatase activity
LFT48_06705	COG1674	ftsk spoiiie
LFT48_06715	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LFT48_06720	COG0483	inositol monophosphate 1-phosphatase activity
LFT48_06730	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LFT48_06740	COG0251	oxidation-reduction process
LFT48_06745	COG4565	transcriptional regulatory protein
LFT48_06755	COG2851	Citrate transporter
LFT48_06770	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LFT48_06775	COG0154	amidase activity
LFT48_06780	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LFT48_06790	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LFT48_06795	COG4209	transmembrane transport
LFT48_06800	COG0395	ABC-type sugar transport system, permease component
LFT48_06815	COG0673	inositol 2-dehydrogenase activity
LFT48_06825	COG1063	alcohol dehydrogenase
LFT48_06830	COG0156	8-amino-7-oxononanoate synthase activity
LFT48_06840	COG1228	amidohydrolase
LFT48_06845	COG1470	cell adhesion involved in biofilm formation
LFT48_06845	COG0366	Alpha amylase catalytic
LFT48_06850	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LFT48_06855	COG1940	carbohydrate kinase activity
LFT48_06865	COG0191	fructose-bisphosphate aldolase activity
LFT48_06875	COG0588	phosphoglycerate mutase activity
LFT48_06890	COG2873	o-acetylhomoserine
LFT48_06895	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LFT48_06930	COG0423	glycine-tRNA ligase activity
LFT48_06955	COG0358	DNA primase activity
LFT48_06975	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
LFT48_06980	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LFT48_06990	COG2814	Major facilitator Superfamily
LFT48_07000	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LFT48_07020	COG1960	acyl-CoA dehydrogenase activity
LFT48_07030	COG0052	Belongs to the universal ribosomal protein uS2 family
LFT48_07035	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LFT48_07040	COG0528	UMP kinase activity
LFT48_07045	COG0233	cytoplasmic translational termination
LFT48_07050	COG0575	Belongs to the CDS family
LFT48_07065	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LFT48_07080	COG3275	phosphorelay sensor kinase activity
LFT48_07090	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LFT48_07095	COG1796	DNA polymerase
LFT48_07095	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
LFT48_07115	COG1522	sequence-specific DNA binding
LFT48_07125	COG0022	dehydrogenase e1 component
LFT48_07130	COG0508	dehydrogenase complex catalyzes the overall conversion of
LFT48_07135	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LFT48_07155	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LFT48_07165	COG1960	acyl-CoA dehydrogenase activity
LFT48_07190	COG0673	inositol 2-dehydrogenase activity
LFT48_07200	COG0673	inositol 2-dehydrogenase activity
LFT48_07210	COG1175	transmembrane transport
LFT48_07215	COG1653	transport
LFT48_07220	COG1609	Transcriptional regulator
LFT48_07230	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
LFT48_07235	COG0750	zinc metalloprotease
LFT48_07245	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
LFT48_07260	COG1309	transcriptional regulator
LFT48_07270	COG1131	(ABC) transporter
LFT48_07275	COG0442	prolyl-tRNA aminoacylation
LFT48_07285	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
LFT48_07290	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
LFT48_07305	COG0779	Required for maturation of 30S ribosomal subunits
LFT48_07325	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LFT48_07325	COG0481	GTPase activity
LFT48_07330	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LFT48_07335	COG0590	tRNA wobble adenosine to inosine editing
LFT48_07345	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LFT48_07365	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LFT48_07370	COG1185	polyribonucleotide nucleotidyltransferase activity
LFT48_07375	COG0612	Peptidase, M16
LFT48_07395	COG0745	RESPONSE REGULATOR receiver
LFT48_07400	COG2205	protein histidine kinase activity
LFT48_07420	COG0521	Mo-molybdopterin cofactor biosynthetic process
LFT48_07430	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
LFT48_07460	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LFT48_07465	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LFT48_07470	COG1674	ftsk spoiiie
LFT48_07480	COG1058	Belongs to the CinA family
LFT48_07480	COG1546	Belongs to the CinA family
LFT48_07485	COG1396	sequence-specific DNA binding
LFT48_07500	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LFT48_07505	COG2137	regulation of response to DNA damage stimulus
LFT48_07510	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LFT48_07515	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LFT48_07520	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LFT48_07525	COG2813	Specifically methylates the guanine in position
LFT48_07530	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LFT48_07540	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LFT48_07545	COG1388	LysM domain
LFT48_07550	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LFT48_07555	COG0131	Imidazoleglycerol-phosphate dehydratase
LFT48_07560	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LFT48_07570	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LFT48_07590	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LFT48_07595	COG0291	Belongs to the bacterial ribosomal protein bL35 family
LFT48_07600	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LFT48_07605	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LFT48_07610	COG2814	Major facilitator Superfamily
LFT48_07645	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LFT48_07650	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LFT48_07650	COG0072	phenylalanine-tRNA ligase activity
LFT48_07655	COG3591	Belongs to the peptidase S1B family
LFT48_07685	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LFT48_07690	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LFT48_07695	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LFT48_07700	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LFT48_07705	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LFT48_07710	COG1438	arginine binding
LFT48_07715	COG0137	argininosuccinate synthase activity
LFT48_07720	COG0165	Argininosuccinate lyase
LFT48_07735	COG2094	Belongs to the DNA glycosylase MPG family
LFT48_07745	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LFT48_07770	COG0647	UMP catabolic process
LFT48_07785	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LFT48_07790	COG0497	DNA recombination
LFT48_07795	COG0504	CTP synthase activity
LFT48_07815	COG0494	nUDIX hydrolase
LFT48_07825	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
LFT48_07830	COG2079	MmgE PrpD family protein
LFT48_07855	COG3290	protein histidine kinase activity
LFT48_07860	COG1301	dicarboxylic acid transport
LFT48_07870	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LFT48_07875	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LFT48_07890	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
LFT48_07900	COG1160	GTP binding
LFT48_07915	COG2814	Major facilitator Superfamily
LFT48_07920	COG0509	glycine decarboxylation via glycine cleavage system
LFT48_07925	COG1716	ATPase activity
LFT48_07950	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
LFT48_07960	COG1940	carbohydrate kinase activity
LFT48_07985	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
LFT48_07990	COG2815	serine threonine protein kinase
LFT48_07990	COG0515	serine threonine protein kinase
LFT48_07995	COG3942	CHAP domain
LFT48_07995	COG1388	LysM domain
LFT48_08005	COG0142	geranyltranstransferase activity
LFT48_08015	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LFT48_08025	COG2001	Belongs to the MraZ family
LFT48_08030	COG0275	rRNA processing
LFT48_08040	COG0768	penicillin binding
LFT48_08045	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LFT48_08055	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LFT48_08060	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LFT48_08070	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LFT48_08075	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LFT48_08085	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LFT48_08100	COG1799	cell septum assembly
LFT48_08115	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LFT48_08140	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LFT48_08145	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LFT48_08150	COG1028	Short-chain dehydrogenase reductase Sdr
LFT48_08170	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
LFT48_08175	COG0174	glutamine synthetase
LFT48_08180	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
LFT48_08215	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LFT48_08220	COG0321	lipoyl(octanoyl) transferase activity
LFT48_08235	COG4946	Tricorn protease homolog
LFT48_08235	COG0793	Belongs to the peptidase S41A family
LFT48_08240	COG1764	response to oxidative stress
LFT48_08250	COG0508	dehydrogenase complex catalyzes the overall conversion of
LFT48_08255	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LFT48_08260	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LFT48_08280	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LFT48_08290	COG0187	DNA topoisomerase II activity
LFT48_08315	COG1271	oxidase subunit
LFT48_08320	COG1294	oxidase, subunit
LFT48_08325	COG4988	ABC transporter
LFT48_08345	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LFT48_08350	COG0045	succinate-CoA ligase (ADP-forming) activity
LFT48_08350	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LFT48_08350	COG1042	CoA-binding domain protein
LFT48_08365	COG1435	thymidine kinase activity
LFT48_08385	COG0756	dUTP diphosphatase activity
LFT48_08410	COG0569	domain protein
LFT48_08415	COG0531	amino acid
LFT48_08420	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LFT48_08425	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LFT48_08430	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LFT48_08450	COG0667	Aldo Keto reductase
LFT48_08455	COG1024	Enoyl-CoA hydratase
LFT48_08455	COG1250	3-hydroxyacyl-CoA dehydrogenase
LFT48_08460	COG0183	Belongs to the thiolase family
LFT48_08490	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LFT48_08505	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LFT48_08525	COG3135	benzoate transporter
LFT48_08535	COG0531	amino acid
LFT48_08585	COG0242	peptide deformylase activity
LFT48_08590	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LFT48_08600	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LFT48_08620	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LFT48_08620	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LFT48_08630	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
LFT48_08635	COG0140	phosphoribosyl-ATP diphosphatase activity
LFT48_08640	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
LFT48_08645	COG0107	imidazoleglycerol-phosphate synthase activity
LFT48_08655	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LFT48_08675	COG0134	indole-3-glycerol-phosphate synthase activity
LFT48_08680	COG0133	tryptophan synthase activity
LFT48_08685	COG0159	tryptophan synthase activity
LFT48_08690	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LFT48_08695	COG0067	glutamate synthase
LFT48_08695	COG0069	glutamate synthase activity
LFT48_08695	COG0070	glutamate synthase
LFT48_08720	COG0583	DNA-binding transcription factor activity
LFT48_08780	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LFT48_08785	COG4172	Belongs to the ABC transporter superfamily
LFT48_08790	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LFT48_08795	COG0601	transmembrane transport
LFT48_08805	COG0277	FAD linked oxidase domain protein
LFT48_08835	COG1850	ribulose-bisphosphate carboxylase activity
LFT48_08845	COG2186	Transcriptional regulator
LFT48_08890	COG0800	Aldolase
LFT48_08900	COG1609	Transcriptional regulator
LFT48_08925	COG0673	inositol 2-dehydrogenase activity
LFT48_08940	COG0395	ABC-type sugar transport system, permease component
LFT48_08970	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LFT48_08980	COG2072	flavoprotein involved in K transport
LFT48_08985	COG1063	alcohol dehydrogenase
LFT48_09010	COG2084	Dehydrogenase
LFT48_09015	COG1082	Xylose isomerase domain protein TIM barrel
LFT48_09020	COG0149	triose-phosphate isomerase activity
LFT48_09025	COG0698	ribose 5-phosphate isomerase
LFT48_09030	COG2376	Dihydroxyacetone kinase
LFT48_09040	COG2186	Transcriptional regulator
LFT48_09060	COG1028	Short-chain dehydrogenase reductase Sdr
LFT48_09080	COG1028	Short-chain dehydrogenase reductase Sdr
LFT48_09110	COG0179	Fumarylacetoacetate (FAA) hydrolase
LFT48_09125	COG2814	Major facilitator Superfamily
LFT48_09130	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LFT48_09150	COG0464	growth
LFT48_09155	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LFT48_09160	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LFT48_09175	COG1012	belongs to the aldehyde dehydrogenase family
LFT48_09185	COG1760	l-serine dehydratase
LFT48_09190	COG0583	DNA-binding transcription factor activity
LFT48_09200	COG2814	Major facilitator Superfamily
LFT48_09210	COG2354	Protein conserved in bacteria
LFT48_09230	COG0601	transmembrane transport
LFT48_09235	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LFT48_09240	COG0444	Belongs to the ABC transporter superfamily
LFT48_09245	COG4608	Belongs to the ABC transporter superfamily
LFT48_09250	COG1621	beta-fructofuranosidase activity
LFT48_09255	COG1621	beta-fructofuranosidase activity
LFT48_09265	COG1121	(ABC) transporter
LFT48_09270	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LFT48_09295	COG2828	Protein conserved in bacteria
LFT48_09305	COG0477	Major facilitator Superfamily
LFT48_09320	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LFT48_09325	COG4172	Belongs to the ABC transporter superfamily
LFT48_09335	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LFT48_09340	COG0318	PFAM AMP-dependent synthetase and ligase
LFT48_09345	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LFT48_09350	COG0531	amino acid
LFT48_09370	COG1278	Cold shock
LFT48_09375	COG0475	glutathione-regulated potassium exporter activity
LFT48_09385	COG1793	dna ligase
LFT48_09385	COG3285	dna ligase
LFT48_09390	COG0028	Belongs to the TPP enzyme family
LFT48_09425	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
LFT48_09445	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LFT48_09460	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LFT48_09475	COG3552	Protein containing von Willebrand factor type A (VWA) domain
LFT48_09485	COG0714	Associated with various cellular activities
LFT48_09510	COG1012	belongs to the aldehyde dehydrogenase family
LFT48_09515	COG2084	Dehydrogenase
LFT48_09520	COG1737	Transcriptional regulator
LFT48_09530	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LFT48_09550	COG1064	alcohol dehydrogenase
LFT48_09555	COG1643	Atp-dependent helicase
LFT48_09600	COG0009	L-threonylcarbamoyladenylate synthase
LFT48_09620	COG2971	BadF BadG BcrA BcrD
LFT48_09625	COG2188	Transcriptional regulator
LFT48_09640	COG1053	succinate dehydrogenase
LFT48_09650	COG0477	Major facilitator Superfamily
LFT48_09665	COG3483	tryptophan 2,3-dioxygenase activity
LFT48_09695	COG2050	protein possibly involved in aromatic compounds catabolism
LFT48_09705	COG4552	Acetyltransferase involved in intracellular survival and related
LFT48_09715	COG0539	negative regulation of cytoplasmic translation
LFT48_09720	COG1739	Uncharacterized protein family UPF0029
LFT48_09725	COG0237	dephospho-CoA kinase activity
LFT48_09725	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LFT48_09730	COG0556	nucleotide-excision repair
LFT48_09755	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LFT48_09765	COG4106	trans-aconitate 2-methyltransferase activity
LFT48_09780	COG0546	phosphoglycolate phosphatase activity
LFT48_09790	COG0322	excinuclease ABC activity
LFT48_09795	COG1660	Displays ATPase and GTPase activities
LFT48_09805	COG1481	regulation of sporulation
LFT48_09810	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LFT48_09815	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LFT48_09820	COG0126	phosphoglycerate kinase activity
LFT48_09825	COG0149	triose-phosphate isomerase activity
LFT48_09830	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LFT48_09840	COG0363	glucosamine-6-phosphate deaminase activity
LFT48_09855	COG0166	Belongs to the GPI family
LFT48_09860	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LFT48_09870	COG0109	protoheme IX farnesyltransferase activity
LFT48_09895	COG0577	efflux transmembrane transporter activity
LFT48_09895	COG1136	(ABC) transporter
LFT48_09900	COG1612	heme a metabolic process
LFT48_09905	COG0842	Transport permease protein
LFT48_09910	COG1131	(ABC) transporter
LFT48_09925	COG0719	Fe-S assembly protein
LFT48_09935	COG0396	ATPase activity
LFT48_09940	COG2151	metal-sulfur cluster biosynthetic enzyme
LFT48_09955	COG0318	PFAM AMP-dependent synthetase and ligase
LFT48_09970	COG1122	ATPase activity
LFT48_09975	COG1268	BioY protein
LFT48_09980	COG0488	(ABC) transporter
LFT48_10005	COG1028	Short-chain dehydrogenase reductase Sdr
LFT48_10010	COG1028	Short-chain dehydrogenase reductase Sdr
LFT48_10015	COG1129	ABC transporter
LFT48_10025	COG0560	Phosphoserine phosphatase
LFT48_10025	COG3830	Belongs to the UPF0237 family
LFT48_10030	COG1119	ATPase activity
LFT48_10045	COG0254	rRNA binding
LFT48_10060	COG2855	membrane
LFT48_10085	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LFT48_10090	COG0297	glycogen (starch) synthase activity
LFT48_10105	COG0183	Belongs to the thiolase family
LFT48_10110	COG1028	Short-chain dehydrogenase reductase Sdr
LFT48_10125	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LFT48_10145	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LFT48_10150	COG0673	inositol 2-dehydrogenase activity
LFT48_10170	COG1215	transferase activity, transferring glycosyl groups
LFT48_10175	COG2244	polysaccharide biosynthetic process
LFT48_10225	COG1088	dTDP-glucose 4,6-dehydratase activity
LFT48_10230	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LFT48_10235	COG0667	Aldo Keto reductase
LFT48_10240	COG1968	undecaprenyl-diphosphatase activity
LFT48_10245	COG0215	cysteine-tRNA ligase activity
LFT48_10255	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LFT48_10260	COG0517	IMP dehydrogenase activity
LFT48_10260	COG1994	Peptidase M50
LFT48_10270	COG1222	aaa ATPase
LFT48_10275	COG4122	O-methyltransferase activity
LFT48_10285	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
LFT48_10290	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
LFT48_10295	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
LFT48_10300	COG0545	Peptidyl-prolyl cis-trans isomerase
LFT48_10320	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LFT48_10325	COG0805	protein transport
LFT48_10330	COG4581	dead DEAH box helicase
LFT48_10335	COG1574	metal-dependent hydrolase with the TIM-barrel fold
LFT48_10340	COG1216	Glycosyl transferase, family 2
LFT48_10365	COG0823	Involved in the tonB-independent uptake of proteins
LFT48_10365	COG1506	peptidase
LFT48_10365	COG4946	Tricorn protease homolog
LFT48_10370	COG0242	peptide deformylase activity
LFT48_10385	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LFT48_10390	COG3424	synthase
LFT48_10395	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LFT48_10430	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LFT48_10435	COG1845	cytochrome c oxidase, subunit III
LFT48_10440	COG2010	Cytochrome c
LFT48_10445	COG0723	plastoquinol--plastocyanin reductase activity
LFT48_10450	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LFT48_10460	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LFT48_10470	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LFT48_10475	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LFT48_10495	COG0167	dihydroorotate dehydrogenase activity
LFT48_10500	COG3573	Dehydrogenase
LFT48_10510	COG2267	carboxylic ester hydrolase activity
LFT48_10515	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LFT48_10520	COG1381	Involved in DNA repair and RecF pathway recombination
LFT48_10525	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LFT48_10530	COG3590	peptidase
LFT48_10535	COG1316	TRANSCRIPTIONal
LFT48_10540	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LFT48_10550	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LFT48_10570	COG0484	heat shock protein binding
LFT48_10575	COG1420	regulation of RNA biosynthetic process
LFT48_10595	COG0481	GTPase activity
LFT48_10605	COG0268	Binds directly to 16S ribosomal RNA
LFT48_10625	COG1307	EDD domain protein, DegV family
LFT48_10630	COG0495	leucyl-tRNA aminoacylation
LFT48_10635	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LFT48_10640	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LFT48_10645	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LFT48_10650	COG2390	Transcriptional regulator
LFT48_10655	COG0656	L-ascorbic acid biosynthetic process
LFT48_10665	COG0438	transferase activity, transferring glycosyl groups
LFT48_10675	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LFT48_10685	COG1758	RNA polymerase activity
LFT48_10690	COG0194	GDP metabolic process
LFT48_10700	COG0284	orotidine-5'-phosphate decarboxylase activity
LFT48_10705	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LFT48_10710	COG0505	Belongs to the CarA family
LFT48_10720	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LFT48_10725	COG0540	Belongs to the ATCase OTCase family
LFT48_10730	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LFT48_10740	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LFT48_10745	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LFT48_10755	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LFT48_10760	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LFT48_10765	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
LFT48_10770	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LFT48_10780	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LFT48_10785	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LFT48_10800	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LFT48_10820	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LFT48_10825	COG0124	histidyl-tRNA synthetase
LFT48_10835	COG1196	nuclear chromosome segregation
LFT48_10845	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LFT48_10850	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LFT48_10855	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LFT48_10865	COG2255	four-way junction helicase activity
LFT48_10870	COG0632	four-way junction helicase activity
LFT48_10875	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
LFT48_10880	COG0217	transcriptional regulatory protein
LFT48_10885	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
LFT48_10890	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LFT48_10910	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
LFT48_10915	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LFT48_10925	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LFT48_10930	COG0587	DNA-directed DNA polymerase activity
LFT48_10955	COG2135	peptidase activity
LFT48_10995	COG0644	oxidoreductase
LFT48_11005	COG4804	nuclease activity
LFT48_11020	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LFT48_11025	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LFT48_11030	COG1780	Probably involved in ribonucleotide reductase function
LFT48_11040	COG0583	DNA-binding transcription factor activity
LFT48_11075	COG0714	Associated with various cellular activities
LFT48_11090	COG1175	transmembrane transport
LFT48_11105	COG2813	Specifically methylates the guanine in position
LFT48_11130	COG0799	negative regulation of ribosome biogenesis
LFT48_11140	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LFT48_11150	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LFT48_11155	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LFT48_11160	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LFT48_11165	COG0211	Belongs to the bacterial ribosomal protein bL27 family
LFT48_11170	COG0261	This protein binds to 23S rRNA in the presence of protein L20
LFT48_11175	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LFT48_11175	COG0351	phosphomethylpyrimidine kinase
LFT48_11175	COG0352	thiamine-phosphate diphosphorylase activity
LFT48_11180	COG1530	ribonuclease E activity
LFT48_11190	COG0105	UTP biosynthetic process
LFT48_11200	COG0285	dihydrofolate synthase activity
LFT48_11205	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LFT48_11220	COG0525	valine-tRNA ligase activity
LFT48_11225	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LFT48_11230	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
LFT48_11235	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LFT48_11240	COG0740	serine-type endopeptidase activity
LFT48_11245	COG0740	serine-type endopeptidase activity
LFT48_11250	COG0544	peptidyl-prolyl cis-trans isomerase activity
LFT48_11295	COG0668	transmembrane transport
LFT48_11310	COG1946	Acyl-CoA thioesterase
LFT48_11340	COG0629	single-stranded DNA binding
LFT48_11375	COG0242	peptide deformylase activity
LFT48_11405	COG3022	response to hydroperoxide
LFT48_11415	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LFT48_11420	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LFT48_11430	COG1045	serine acetyltransferase
LFT48_11435	COG0300	oxidoreductase activity
LFT48_11440	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LFT48_11450	COG1063	alcohol dehydrogenase
LFT48_11455	COG1028	Short-chain dehydrogenase reductase Sdr
LFT48_11475	COG0477	Major facilitator Superfamily
LFT48_11510	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
LFT48_11525	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LFT48_11530	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LFT48_11545	COG4974	Belongs to the 'phage' integrase family
LFT48_11580	COG1061	Type III restriction enzyme res subunit
LFT48_11585	COG1002	Type II restriction enzyme, methylase subunits
LFT48_11680	COG0085	RNA polymerase activity
LFT48_11710	COG1793	dna ligase
LFT48_11765	COG1074	ATP-dependent DNA helicase activity
LFT48_11775	COG0542	response to heat
LFT48_11840	COG1028	Short-chain dehydrogenase reductase Sdr
LFT48_11850	COG0500	methyltransferase
LFT48_11920	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
LFT48_12015	COG0750	zinc metalloprotease
LFT48_12175	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LFT48_12260	COG0210	DNA helicase
LFT48_12390	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
LFT48_12405	COG0686	Belongs to the AlaDH PNT family
LFT48_12430	COG0512	Glutamine amidotransferase of anthranilate synthase
LFT48_12450	COG2124	cytochrome p450
LFT48_12455	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
LFT48_12460	COG1028	Short-chain dehydrogenase reductase Sdr
LFT48_12485	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LFT48_12490	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
LFT48_12495	COG1012	belongs to the aldehyde dehydrogenase family
LFT48_12500	COG1473	amidohydrolase
LFT48_12510	COG0792	nuclease activity
LFT48_12520	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LFT48_12530	COG0681	Belongs to the peptidase S26 family
LFT48_12535	COG0335	large ribosomal subunit rRNA binding
LFT48_12540	COG0336	Belongs to the RNA methyltransferase TrmD family
LFT48_12545	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LFT48_12550	COG1837	Belongs to the UPF0109 family
LFT48_12555	COG0228	four-way junction DNA binding
LFT48_12565	COG2514	catechol 2,3-dioxygenase activity
LFT48_12590	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LFT48_12605	COG2814	Major facilitator Superfamily
LFT48_12640	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LFT48_12645	COG0571	ribonuclease III activity
LFT48_12650	COG0333	Belongs to the bacterial ribosomal protein bL32 family
LFT48_12660	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LFT48_12675	COG0742	ribosomal rna small subunit methyltransferase
LFT48_12700	COG1181	Belongs to the D-alanine--D-alanine ligase family
LFT48_12705	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
LFT48_12715	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LFT48_12720	COG0066	3-isopropylmalate dehydratase activity
LFT48_12725	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LFT48_12730	COG1414	Transcriptional regulator
LFT48_12765	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LFT48_12770	COG0179	Fumarylacetoacetate (FAA) hydrolase
LFT48_12775	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LFT48_12780	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LFT48_12785	COG0473	3-isopropylmalate dehydrogenase activity
LFT48_12790	COG4585	Histidine kinase
LFT48_12795	COG2197	response regulator
LFT48_12800	COG0577	efflux transmembrane transporter activity
LFT48_12800	COG1136	(ABC) transporter
LFT48_12815	COG0577	efflux transmembrane transporter activity
LFT48_12815	COG1136	(ABC) transporter
LFT48_12825	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LFT48_12830	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LFT48_12835	COG0440	acetolactate synthase activity
LFT48_12845	COG0129	dihydroxy-acid dehydratase activity
LFT48_12860	COG2133	pyrroloquinoline quinone binding
LFT48_12890	COG0747	negative chemotaxis
LFT48_12895	COG0579	oxidoreductase
LFT48_12900	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LFT48_12905	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LFT48_12915	COG1305	Transglutaminase-like
LFT48_12950	COG1104	cysteine desulfurase activity
LFT48_12960	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
LFT48_12965	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LFT48_12975	COG1522	sequence-specific DNA binding
LFT48_12980	COG1113	amino acid transport
LFT48_12990	COG0022	dehydrogenase e1 component
LFT48_12995	COG0508	dehydrogenase complex catalyzes the overall conversion of
LFT48_13015	COG0477	Major facilitator Superfamily
LFT48_13020	COG1414	Transcriptional regulator
LFT48_13030	COG0531	amino acid
LFT48_13045	COG1116	anion transmembrane transporter activity
LFT48_13050	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LFT48_13065	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
LFT48_13080	COG0419	ATPase involved in DNA repair
LFT48_13085	COG0420	3'-5' exonuclease activity
LFT48_13100	COG2149	membrane
LFT48_13120	COG1131	(ABC) transporter
LFT48_13135	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LFT48_13140	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
LFT48_13145	COG1234	tRNA 3'-trailer cleavage
LFT48_13150	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
LFT48_13160	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
LFT48_13170	COG1335	isochorismatase
LFT48_13185	COG0363	glucosamine-6-phosphate deaminase activity
LFT48_13200	COG1902	pentaerythritol trinitrate reductase activity
LFT48_13230	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
LFT48_13235	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LFT48_13245	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LFT48_13250	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
LFT48_13260	COG0355	proton-transporting ATP synthase activity, rotational mechanism
LFT48_13265	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LFT48_13270	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LFT48_13275	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LFT48_13280	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LFT48_13285	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LFT48_13290	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LFT48_13300	COG0356	it plays a direct role in the translocation of protons across the membrane
LFT48_13315	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LFT48_13320	COG1216	Glycosyl transferase, family 2
LFT48_13330	COG0009	L-threonylcarbamoyladenylate synthase
LFT48_13335	COG2890	protein-(glutamine-N5) methyltransferase activity
LFT48_13340	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LFT48_13350	COG0083	homoserine kinase activity
LFT48_13355	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LFT48_13360	COG0460	homoserine dehydrogenase
LFT48_13365	COG0019	diaminopimelate decarboxylase activity
LFT48_13370	COG0018	arginyl-trna synthetase
LFT48_13385	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LFT48_13385	COG1017	nitric oxide dioxygenase activity
LFT48_13420	COG1643	Atp-dependent helicase
LFT48_13425	COG0537	adenosine 5'-monophosphoramidase activity
LFT48_13430	COG1064	alcohol dehydrogenase
LFT48_13445	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
LFT48_13455	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LFT48_13460	COG1121	(ABC) transporter
LFT48_13465	COG0803	Belongs to the bacterial solute-binding protein 9 family
LFT48_13475	COG1253	flavin adenine dinucleotide binding
LFT48_13480	COG0508	dehydrogenase complex catalyzes the overall conversion of
LFT48_13480	COG0567	Dehydrogenase, E1 component
LFT48_13510	COG1595	DNA-templated transcription, initiation
LFT48_13520	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
LFT48_13530	COG0483	inositol monophosphate 1-phosphatase activity
LFT48_13535	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LFT48_13560	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LFT48_13570	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
LFT48_13580	COG2177	Part of the ABC transporter FtsEX involved in
LFT48_13585	COG2884	Cell division ATP-binding protein ftsE
LFT48_13590	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
LFT48_13655	COG1216	Glycosyl transferase, family 2
LFT48_13680	COG1216	Glycosyl transferase, family 2
LFT48_13695	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LFT48_13725	COG2902	Dehydrogenase
LFT48_13760	COG0653	protein targeting
LFT48_13765	COG3214	Protein conserved in bacteria
LFT48_13770	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LFT48_13780	COG5401	PFAM Sporulation and spore germination
LFT48_13785	COG5002	protein histidine kinase activity
LFT48_13815	COG0714	Associated with various cellular activities
LFT48_13850	COG0601	transmembrane transport
LFT48_13860	COG0482	sulfurtransferase activity
LFT48_13880	COG0484	heat shock protein binding
LFT48_13885	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LFT48_13905	COG3265	gluconokinase activity
LFT48_13915	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
LFT48_13920	COG2086	electron transfer activity
LFT48_13925	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LFT48_13935	COG1842	Phage shock protein A
LFT48_13940	COG2188	Transcriptional regulator
LFT48_13955	COG1615	UPF0182 protein
LFT48_13960	COG3480	Lon protease (S16) C-terminal proteolytic domain
LFT48_13980	COG2816	NAD+ diphosphatase activity
LFT48_14010	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LFT48_14015	COG0765	amino acid transport
LFT48_14020	COG1126	abc transporter atp-binding protein
LFT48_14025	COG1472	Belongs to the glycosyl hydrolase 3 family
LFT48_14030	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
LFT48_14040	COG0113	porphobilinogen synthase activity
LFT48_14050	COG0181	hydroxymethylbilane synthase activity
LFT48_14055	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
LFT48_14060	COG3253	May function as heme-dependent peroxidase
LFT48_14070	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
LFT48_14075	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
LFT48_14085	COG1309	transcriptional regulator
LFT48_14100	COG2154	pterin-4-alpha-carbinolamine dehydratase
LFT48_14105	COG2022	thiamine diphosphate biosynthetic process
LFT48_14115	COG2022	thiamine diphosphate biosynthetic process
LFT48_14115	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LFT48_14120	COG0352	thiamine-phosphate diphosphorylase activity
LFT48_14140	COG0513	Belongs to the DEAD box helicase family
LFT48_14150	COG2095	MarC family integral membrane protein
LFT48_14160	COG0006	proline dipeptidase activity
LFT48_14170	COG2239	Acts as a magnesium transporter
LFT48_14185	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LFT48_14195	COG1595	DNA-templated transcription, initiation
LFT48_14220	COG1611	Belongs to the LOG family
LFT48_14225	COG1126	abc transporter atp-binding protein
LFT48_14230	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LFT48_14235	COG0765	amino acid transport
LFT48_14240	COG0765	amino acid transport
LFT48_14245	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LFT48_14250	COG2171	N-acyltransferase activity
LFT48_14265	COG3226	Transcriptional regulator
LFT48_14270	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LFT48_14295	COG1217	gtp-binding protein TYPA
LFT48_14310	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LFT48_14315	COG0601	transmembrane transport
LFT48_14320	COG0747	negative chemotaxis
LFT48_14330	COG0012	GTP binding
LFT48_14335	COG1322	Protein conserved in bacteria
LFT48_14340	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LFT48_14350	COG1570	exodeoxyribonuclease VII activity
LFT48_14355	COG1722	exodeoxyribonuclease VII activity
LFT48_14360	COG2326	polyphosphate kinase activity
LFT48_14380	COG1174	glycine betaine transport
LFT48_14390	COG1162	GTPase activity
LFT48_14410	COG2971	BadF BadG BcrA BcrD
LFT48_14420	COG0583	DNA-binding transcription factor activity
LFT48_14425	COG2814	Major facilitator Superfamily
LFT48_14430	COG3548	integral membrane protein
LFT48_14455	COG0598	Magnesium transport protein CorA
LFT48_14460	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
LFT48_14465	COG1528	Iron-storage protein
LFT48_14470	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LFT48_14475	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LFT48_14485	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LFT48_14490	COG1695	Transcriptional regulator
LFT48_14540	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LFT48_14545	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LFT48_14565	COG0519	Catalyzes the synthesis of GMP from XMP
LFT48_14565	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LFT48_14585	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LFT48_14590	COG0516	GMP reductase activity
LFT48_14595	COG1132	(ABC) transporter
LFT48_14615	COG2072	flavoprotein involved in K transport
LFT48_14625	COG2197	response regulator
LFT48_14630	COG0459	protein refolding
LFT48_14635	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LFT48_14650	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LFT48_14655	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LFT48_14665	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
LFT48_14670	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LFT48_14685	COG0802	atpase or kinase
LFT48_14690	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LFT48_14700	COG1486	melibiose metabolic process
LFT48_14710	COG0438	transferase activity, transferring glycosyl groups
LFT48_14715	COG2759	Belongs to the formate--tetrahydrofolate ligase family
LFT48_14725	COG0667	Aldo Keto reductase
LFT48_14750	COG0736	holo-[acyl-carrier-protein] synthase activity
LFT48_14760	COG1072	(Pantothenic acid kinase))
LFT48_14770	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LFT48_14775	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LFT48_14780	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LFT48_14810	COG2894	cell division
LFT48_14830	COG0101	tRNA pseudouridine synthase activity
LFT48_14835	COG0203	ribosomal protein L17
LFT48_14840	COG0202	RNA polymerase activity
LFT48_14845	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LFT48_14850	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LFT48_14855	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LFT48_14860	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LFT48_14865	COG3191	aminopeptidase activity
LFT48_14875	COG0395	ABC-type sugar transport system, permease component
LFT48_14885	COG0024	Methionine aminopeptidase
LFT48_14890	COG0563	adenylate kinase activity
LFT48_14900	COG0200	Binds to the 23S rRNA
LFT48_14905	COG1841	ribosomal large subunit assembly
LFT48_14910	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LFT48_14920	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LFT48_14925	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LFT48_14930	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LFT48_14935	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LFT48_14940	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LFT48_14945	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LFT48_14955	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LFT48_14960	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LFT48_14965	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LFT48_14970	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LFT48_14975	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LFT48_14980	COG0089	rRNA binding
LFT48_14985	COG0088	Forms part of the polypeptide exit tunnel
LFT48_14990	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LFT48_14995	COG0051	transcription antitermination factor activity, RNA binding
LFT48_15010	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LFT48_15015	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LFT48_15020	COG0049	tRNA binding
LFT48_15025	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LFT48_15030	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LFT48_15035	COG0085	RNA polymerase activity
LFT48_15040	COG0183	Belongs to the thiolase family
LFT48_15045	COG0442	prolyl-tRNA aminoacylation
LFT48_15050	COG0222	ribosome binding
LFT48_15055	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LFT48_15070	COG0081	regulation of translation
LFT48_15075	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LFT48_15085	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LFT48_15095	COG0436	Aminotransferase
LFT48_15100	COG2197	response regulator
LFT48_15150	COG0404	The glycine cleavage system catalyzes the degradation of glycine
LFT48_15160	COG3485	protocatechuate 3,4-dioxygenase
LFT48_15170	COG0745	RESPONSE REGULATOR receiver
LFT48_15175	COG0456	acetyltransferase
LFT48_15180	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LFT48_15200	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LFT48_15205	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LFT48_15215	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LFT48_15235	COG0812	UDP-N-acetylmuramate dehydrogenase activity
LFT48_15240	COG0738	Major facilitator superfamily
LFT48_15245	COG2030	dehydratase
LFT48_15250	COG2030	dehydratase
LFT48_15280	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LFT48_15290	COG4989	oxidoreductase activity
LFT48_15295	COG0366	Alpha amylase catalytic
LFT48_15300	COG0395	ABC-type sugar transport system, permease component
LFT48_15305	COG1175	transmembrane transport
LFT48_15315	COG1846	Transcriptional regulator
LFT48_15315	COG1940	carbohydrate kinase activity
LFT48_15325	COG0702	epimerase
LFT48_15340	COG1652	LysM domain
LFT48_15370	COG0754	glutathionylspermidine amidase activity
LFT48_15395	COG1175	transmembrane transport
LFT48_15400	COG0395	ABC-type sugar transport system, permease component
LFT48_15455	COG0318	PFAM AMP-dependent synthetase and ligase
LFT48_15465	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LFT48_15470	COG1309	transcriptional regulator
LFT48_15475	COG1131	(ABC) transporter
LFT48_15495	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LFT48_15510	COG1666	GTP binding
LFT48_15515	COG0672	)-iron permease
LFT48_15525	COG2837	iron assimilation
LFT48_15530	COG0501	Belongs to the peptidase M48B family
LFT48_15560	COG0531	amino acid
LFT48_15600	COG1012	belongs to the aldehyde dehydrogenase family
LFT48_15605	COG2508	Transcriptional regulator
LFT48_15610	COG2807	transmembrane transport
LFT48_15615	COG2186	Transcriptional regulator
LFT48_15620	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LFT48_15620	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LFT48_15630	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LFT48_15630	COG1648	precorrin-2 dehydrogenase activity
LFT48_15640	COG2066	Belongs to the glutaminase family
LFT48_15645	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LFT48_15670	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LFT48_15685	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LFT48_15690	COG1116	anion transmembrane transporter activity
LFT48_15700	COG2040	homocysteine
LFT48_15705	COG2895	sulfate adenylyltransferase (ATP) activity
LFT48_15770	COG2860	membrane
LFT48_15785	COG0142	geranyltranstransferase activity
LFT48_15795	COG2226	methyltransferase
LFT48_15800	COG1169	isochorismate synthase
LFT48_15805	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LFT48_15810	COG0765	amino acid transport
LFT48_15820	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
LFT48_15835	COG4948	Mandelate Racemase Muconate Lactonizing
LFT48_15870	COG0395	ABC-type sugar transport system, permease component
LFT48_15875	COG1175	transmembrane transport
LFT48_15920	COG1404	Belongs to the peptidase S8 family
LFT48_15970	COG0508	dehydrogenase complex catalyzes the overall conversion of
LFT48_15975	COG0022	dehydrogenase e1 component
LFT48_15995	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LFT48_16000	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LFT48_16005	COG1088	dTDP-glucose 4,6-dehydratase activity
LFT48_16015	COG0489	protein tyrosine kinase activity
LFT48_16065	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LFT48_16095	COG2755	lipolytic protein G-D-S-L family
LFT48_16095	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
LFT48_16145	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LFT48_16155	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
LFT48_16160	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
LFT48_16165	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
LFT48_16230	COG0590	tRNA wobble adenosine to inosine editing
LFT48_16260	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
LFT48_16290	COG3979	chitinase
LFT48_16300	COG1024	Enoyl-CoA hydratase
LFT48_16305	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LFT48_16310	COG2151	metal-sulfur cluster biosynthetic enzyme
LFT48_16315	COG3396	Phenylacetate-CoA oxygenase
LFT48_16320	COG3460	Phenylacetate-CoA oxygenase
LFT48_16325	COG3396	Phenylacetate-CoA oxygenase
LFT48_16330	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LFT48_16335	COG3942	CHAP domain
LFT48_16335	COG1388	LysM domain
LFT48_16340	COG1316	TRANSCRIPTIONal
LFT48_16345	COG0681	Belongs to the peptidase S26 family
LFT48_16360	COG4251	negative regulation of phosphorylation
LFT48_16360	COG5001	Diguanylate cyclase
LFT48_16360	COG3706	GGDEF domain
LFT48_16360	COG2203	Gaf domain
LFT48_16395	COG0438	transferase activity, transferring glycosyl groups
LFT48_16400	COG1215	transferase activity, transferring glycosyl groups
LFT48_16410	COG2226	methyltransferase
LFT48_16420	COG5002	protein histidine kinase activity
LFT48_16445	COG2050	protein possibly involved in aromatic compounds catabolism
LFT48_16465	COG1012	belongs to the aldehyde dehydrogenase family
LFT48_16465	COG2030	dehydratase
LFT48_16475	COG1609	Transcriptional regulator
LFT48_16480	COG2182	Extracellular solute-binding protein
LFT48_16490	COG0395	ABC-type sugar transport system, permease component
LFT48_16500	COG0673	inositol 2-dehydrogenase activity
LFT48_16505	COG2755	lipolytic protein G-D-S-L family
LFT48_16515	COG1250	3-hydroxyacyl-CoA dehydrogenase
LFT48_16520	COG1024	Enoyl-CoA hydratase
LFT48_16545	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LFT48_16555	COG0488	(ABC) transporter
LFT48_16570	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LFT48_16575	COG1121	(ABC) transporter
LFT48_16580	COG0803	Belongs to the bacterial solute-binding protein 9 family
LFT48_16585	COG1266	CAAX protease self-immunity
LFT48_16595	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LFT48_16645	COG0443	Heat shock 70 kDa protein
LFT48_16650	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LFT48_16660	COG0785	Cytochrome C biogenesis protein
LFT48_16670	COG0406	alpha-ribazole phosphatase activity
LFT48_16690	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
LFT48_16725	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LFT48_16730	COG3458	cephalosporin-C deacetylase activity
LFT48_16740	COG2814	Major facilitator Superfamily
LFT48_16750	COG0395	ABC-type sugar transport system, permease component
LFT48_16755	COG1175	transmembrane transport
LFT48_16775	COG0395	ABC-type sugar transport system, permease component
LFT48_16780	COG1175	transmembrane transport
LFT48_16805	COG4948	Mandelate Racemase Muconate Lactonizing
LFT48_16810	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LFT48_16820	COG0673	inositol 2-dehydrogenase activity
LFT48_16825	COG1609	Transcriptional regulator
LFT48_16830	COG1802	Transcriptional regulator
LFT48_16840	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LFT48_16845	COG0640	Transcriptional regulator
LFT48_16850	COG0123	including yeast histone deacetylase and acetoin utilization protein
LFT48_16855	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LFT48_16860	COG0569	domain protein
LFT48_16865	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LFT48_16870	COG1082	Xylose isomerase domain protein TIM barrel
LFT48_16875	COG0248	Ppx GppA phosphatase
LFT48_16885	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LFT48_16885	COG1754	DNA topoisomerase type I activity
LFT48_16895	COG2890	protein-(glutamine-N5) methyltransferase activity
LFT48_16910	COG1054	Belongs to the UPF0176 family
LFT48_16920	COG1205	dead DEAH box helicase
LFT48_16920	COG1111	helicase
LFT48_16985	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LFT48_16990	COG1349	DNA-binding transcription factor activity
LFT48_16995	COG1136	(ABC) transporter
LFT48_16995	COG0577	efflux transmembrane transporter activity
LFT48_17005	COG1609	Transcriptional regulator
LFT48_17015	COG1175	transmembrane transport
LFT48_17020	COG0395	ABC-type sugar transport system, permease component
LFT48_17045	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
LFT48_17065	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LFT48_17070	COG1408	metallophosphoesterase
LFT48_17075	COG1132	(ABC) transporter
LFT48_17080	COG1132	(ABC) transporter
LFT48_17100	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
LFT48_17105	COG0151	Belongs to the GarS family
LFT48_17120	COG1301	dicarboxylic acid transport
LFT48_17130	COG1028	Short-chain dehydrogenase reductase Sdr
LFT48_17140	COG1953	Uracil, thiamine, allantoin
LFT48_17145	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
LFT48_17170	COG1529	Aldehyde oxidase and xanthine dehydrogenase
LFT48_17180	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
LFT48_17180	COG3608	succinylglutamate desuccinylase aspartoacylase
LFT48_17185	COG2252	PERMEase
LFT48_17190	COG0590	tRNA wobble adenosine to inosine editing
LFT48_17215	COG2233	PERMEase
LFT48_17225	COG1414	Transcriptional regulator
LFT48_17235	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
LFT48_17245	COG3257	ureidoglycine aminohydrolase activity
LFT48_17260	COG2318	DinB family
LFT48_17270	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LFT48_17270	COG4499	WXG100 protein secretion system (Wss), protein YukC
LFT48_17275	COG1053	succinate dehydrogenase
LFT48_17285	COG1902	pentaerythritol trinitrate reductase activity
LFT48_17285	COG0446	pyridine nucleotide-disulphide oxidoreductase
LFT48_17290	COG0673	inositol 2-dehydrogenase activity
LFT48_17295	COG0477	Major facilitator Superfamily
LFT48_17300	COG1414	Transcriptional regulator
LFT48_17305	COG0583	DNA-binding transcription factor activity
LFT48_17315	COG1063	alcohol dehydrogenase
LFT48_17320	COG1053	succinate dehydrogenase
LFT48_17330	COG2814	Major facilitator Superfamily
LFT48_17345	COG0659	secondary active sulfate transmembrane transporter activity
LFT48_17370	COG0563	adenylate kinase activity
LFT48_17390	COG0477	Major facilitator Superfamily
LFT48_17400	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LFT48_17410	COG3401	FG-GAP repeat protein
LFT48_17415	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LFT48_17425	COG0477	Major facilitator Superfamily
LFT48_17435	COG2011	ABC-type metal ion transport system permease component
LFT48_17440	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LFT48_17445	COG1464	Belongs to the NlpA lipoprotein family
LFT48_17450	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LFT48_17485	COG1028	Short-chain dehydrogenase reductase Sdr
LFT48_17530	COG0667	Aldo Keto reductase
LFT48_17535	COG2267	carboxylic ester hydrolase activity
LFT48_17605	COG1733	regulation of RNA biosynthetic process
LFT48_17610	COG0405	Gamma-glutamyltransferase
LFT48_17660	COG1454	alcohol dehydrogenase
LFT48_17665	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LFT48_17680	COG0477	Major facilitator Superfamily
LFT48_17685	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LFT48_17695	COG0583	DNA-binding transcription factor activity
LFT48_17745	COG0673	inositol 2-dehydrogenase activity
LFT48_17760	COG1653	transport
LFT48_17765	COG1609	Transcriptional regulator
LFT48_17790	COG3622	Belongs to the hyi family
LFT48_17795	COG2084	Dehydrogenase
LFT48_17800	COG3960	tartronate-semialdehyde synthase activity
LFT48_17805	COG1929	Belongs to the glycerate kinase type-1 family
LFT48_17810	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LFT48_17815	COG0745	RESPONSE REGULATOR receiver
LFT48_17825	COG0745	RESPONSE REGULATOR receiver
LFT48_17830	COG1215	transferase activity, transferring glycosyl groups
LFT48_17835	COG1366	Belongs to the anti-sigma-factor antagonist family
LFT48_17865	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
LFT48_17870	COG0671	phosphoesterase, PA-phosphatase related
LFT48_17895	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
LFT48_17920	COG0542	response to heat
LFT48_17945	COG3585	molybdate ion transport
LFT48_17960	COG3304	Inner membrane component domain
LFT48_17970	COG0135	phosphoribosylanthranilate isomerase activity
LFT48_17990	COG0667	Aldo Keto reductase
LFT48_18015	COG0500	methyltransferase
LFT48_18025	COG1473	amidohydrolase
LFT48_18030	COG0477	Major facilitator Superfamily
LFT48_18035	COG2807	transmembrane transport
LFT48_18045	COG3813	Protein conserved in bacteria
LFT48_18050	COG0220	tRNA (guanine-N7-)-methyltransferase activity
LFT48_18090	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LFT48_18130	COG1609	Transcriptional regulator
LFT48_18140	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LFT48_18145	COG1653	transport
LFT48_18150	COG1175	transmembrane transport
LFT48_18155	COG0395	ABC-type sugar transport system, permease component
LFT48_18175	COG0154	amidase activity
LFT48_18180	COG2957	Belongs to the agmatine deiminase family
LFT48_18225	COG1414	Transcriptional regulator
LFT48_18235	COG3959	Transketolase, thiamine diphosphate binding domain
LFT48_18240	COG3958	Transketolase
LFT48_18245	COG1105	Belongs to the carbohydrate kinase PfkB family
LFT48_18250	COG1028	Short-chain dehydrogenase reductase Sdr
LFT48_18260	COG0477	Major facilitator Superfamily
LFT48_18265	COG4221	oxidoreductase activity
LFT48_18270	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LFT48_18295	COG0800	Aldolase
LFT48_18300	COG1028	Short-chain dehydrogenase reductase Sdr
LFT48_18305	COG1063	alcohol dehydrogenase
LFT48_18310	COG1063	alcohol dehydrogenase
LFT48_18315	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LFT48_18325	COG2140	Oxalate decarboxylase
LFT48_18330	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LFT48_18335	COG1737	Transcriptional regulator
LFT48_18340	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LFT48_18345	COG0789	Transcriptional regulator
LFT48_18350	COG0484	heat shock protein binding
LFT48_18355	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LFT48_18360	COG0443	Heat shock 70 kDa protein
LFT48_18370	COG3739	integral membrane protein
LFT48_18400	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LFT48_18405	COG3119	arylsulfatase activity
LFT48_18415	COG1175	transmembrane transport
LFT48_18420	COG0395	ABC-type sugar transport system, permease component
LFT48_18450	COG0673	inositol 2-dehydrogenase activity
LFT48_18455	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LFT48_18460	COG3684	Belongs to the aldolase LacD family
LFT48_18470	COG1175	transmembrane transport
LFT48_18475	COG0395	ABC-type sugar transport system, permease component
LFT48_18480	COG1012	belongs to the aldehyde dehydrogenase family
LFT48_18505	COG1609	Transcriptional regulator
LFT48_18515	COG1653	transport
LFT48_18545	COG3540	Alkaline phosphatase
LFT48_18585	COG3226	Transcriptional regulator
LFT48_18590	COG1280	lysine exporter protein (LysE YggA)
LFT48_18615	COG0492	ferredoxin-NADP+ reductase activity
LFT48_18620	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LFT48_18625	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LFT48_18630	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LFT48_18650	COG2409	Drug exporters of the RND superfamily
LFT48_18665	COG3795	YCII-related domain
LFT48_18670	COG4941	Belongs to the sigma-70 factor family
LFT48_18675	COG0667	Aldo Keto reductase
LFT48_18685	COG1280	lysine exporter protein (LysE YggA)
LFT48_18690	COG1609	Transcriptional regulator
LFT48_18695	COG1957	nucleoside hydrolase
LFT48_18700	COG0477	Major facilitator Superfamily
LFT48_18705	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LFT48_18715	COG1309	transcriptional regulator
LFT48_18720	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LFT48_18730	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LFT48_18740	COG0833	amino acid
LFT48_18745	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LFT48_18755	COG2986	histidine ammonia-lyase
LFT48_18790	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
LFT48_18795	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LFT48_18830	COG1122	ATPase activity
LFT48_18835	COG4721	ABC-type cobalt transport system, permease component
LFT48_18850	COG1320	monovalent cation:proton antiporter activity
LFT48_18855	COG2212	antiporter activity
LFT48_18865	COG0651	ATP synthesis coupled electron transport
LFT48_18870	COG1006	Multisubunit Na H antiporter MnhC subunit
LFT48_18875	COG2111	Na H antiporter
LFT48_18875	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LFT48_18885	COG0471	metal ion transport
LFT48_18885	COG0490	domain, Protein
LFT48_18890	COG0475	glutathione-regulated potassium exporter activity
LFT48_18900	COG0717	Belongs to the dCTP deaminase family
LFT48_18925	COG0686	Belongs to the AlaDH PNT family
LFT48_18935	COG0583	DNA-binding transcription factor activity
LFT48_18945	COG0640	Transcriptional regulator
LFT48_18960	COG0657	acetylesterase activity
LFT48_18960	COG2755	lipolytic protein G-D-S-L family
LFT48_18965	COG1609	Transcriptional regulator
LFT48_18970	COG0673	inositol 2-dehydrogenase activity
LFT48_19005	COG2115	Belongs to the xylose isomerase family
LFT48_19010	COG1070	Carbohydrate kinase
LFT48_19015	COG1609	Transcriptional regulator
LFT48_19030	COG2160	L-arabinose isomerase activity
LFT48_19035	COG2017	converts alpha-aldose to the beta-anomer
LFT48_19040	COG1609	Transcriptional regulator
LFT48_19045	COG3254	rhamnose metabolic process
LFT48_19055	COG1028	Short-chain dehydrogenase reductase Sdr
LFT48_19055	COG3347	Dehydrogenase
LFT48_19060	COG1070	Carbohydrate kinase
LFT48_19065	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
LFT48_19075	COG3387	PFAM Glycoside hydrolase 15-related
LFT48_19080	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LFT48_19095	COG0583	DNA-binding transcription factor activity
LFT48_19105	COG0477	Major facilitator Superfamily
LFT48_19110	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LFT48_19115	COG0154	amidase activity
LFT48_19120	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LFT48_19125	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LFT48_19130	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LFT48_19160	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LFT48_19165	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LFT48_19185	COG1126	abc transporter atp-binding protein
LFT48_19190	COG0765	amino acid transport
LFT48_19205	COG0433	COG0433 Predicted ATPase
LFT48_19225	COG3336	cytochrome c oxidase
LFT48_19230	COG0776	regulation of translation
LFT48_19260	COG0596	Alpha beta hydrolase
LFT48_19285	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LFT48_19290	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LFT48_19295	COG0227	Belongs to the bacterial ribosomal protein bL28 family
LFT48_19325	COG1120	ATPase activity
LFT48_19330	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LFT48_19335	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LFT48_19375	COG3012	SEC-C Motif Domain Protein
LFT48_19390	COG0667	Aldo Keto reductase
LFT48_19445	COG2186	Transcriptional regulator
LFT48_19455	COG1027	Aspartate ammonia-lyase
LFT48_19465	COG2186	Transcriptional regulator
LFT48_19480	COG3254	rhamnose metabolic process
LFT48_19490	COG4948	Mandelate Racemase Muconate Lactonizing
LFT48_19505	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LFT48_19520	COG4221	oxidoreductase activity
LFT48_19530	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LFT48_19535	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LFT48_19550	COG1280	lysine exporter protein (LysE YggA)
LFT48_19560	COG0640	Transcriptional regulator
LFT48_19575	COG1414	Transcriptional regulator
LFT48_19585	COG0477	Major facilitator Superfamily
LFT48_19590	COG1802	Transcriptional regulator
LFT48_19595	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LFT48_19620	COG1760	l-serine dehydratase
LFT48_19650	COG0281	malic enzyme
LFT48_19655	COG1309	transcriptional regulator
LFT48_19685	COG0477	Major facilitator Superfamily
LFT48_19690	COG2986	histidine ammonia-lyase
LFT48_19695	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
LFT48_19725	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LFT48_19735	COG0477	Major facilitator Superfamily
LFT48_19740	COG2814	Major facilitator Superfamily
LFT48_19745	COG1846	Transcriptional regulator
LFT48_19775	COG1113	amino acid transport
LFT48_19785	COG4604	ABC transporter, ATP-binding protein
LFT48_19790	COG4605	iron ion homeostasis
LFT48_19795	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LFT48_19805	COG0246	Mannitol dehydrogenase
LFT48_19820	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LFT48_19825	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LFT48_19840	COG0596	Alpha beta hydrolase
LFT48_19850	COG1793	dna ligase
LFT48_19870	COG0686	Belongs to the AlaDH PNT family
LFT48_19900	COG0673	inositol 2-dehydrogenase activity
LFT48_19925	COG1309	transcriptional regulator
LFT48_19955	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LFT48_19970	COG0531	amino acid
LFT48_19975	COG0402	S-adenosylhomocysteine deaminase activity
LFT48_19985	COG0508	dehydrogenase complex catalyzes the overall conversion of
LFT48_19990	COG0022	dehydrogenase e1 component
LFT48_20000	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LFT48_20005	COG1950	PFAM Membrane protein of
LFT48_20020	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LFT48_20025	COG0406	alpha-ribazole phosphatase activity
LFT48_20035	COG1607	acyl-coa hydrolase
LFT48_20050	COG3971	2-oxopent-4-enoate hydratase activity
LFT48_20065	COG1802	Transcriptional regulator
LFT48_20070	COG0179	Fumarylacetoacetate (FAA) hydrolase
LFT48_20095	COG2261	transglycosylase associated protein
LFT48_20105	COG2207	Transcriptional regulator
LFT48_20105	COG3708	Transcriptional regulator
LFT48_20115	COG1028	Short-chain dehydrogenase reductase Sdr
LFT48_20175	COG1472	Belongs to the glycosyl hydrolase 3 family
LFT48_20185	COG4209	transmembrane transport
LFT48_20190	COG0395	ABC-type sugar transport system, permease component
LFT48_20195	COG1609	Transcriptional regulator
LFT48_20205	COG1501	Belongs to the glycosyl hydrolase 31 family
LFT48_20220	COG0318	PFAM AMP-dependent synthetase and ligase
LFT48_20225	COG0183	Belongs to the thiolase family
LFT48_20235	COG1028	Short-chain dehydrogenase reductase Sdr
LFT48_20240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LFT48_20245	COG0765	amino acid transport
LFT48_20250	COG0765	amino acid transport
LFT48_20255	COG1126	abc transporter atp-binding protein
LFT48_20300	COG0726	polysaccharide deacetylase
LFT48_20305	COG2815	serine threonine protein kinase
LFT48_20305	COG0515	serine threonine protein kinase
LFT48_20315	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
LFT48_20370	COG1396	sequence-specific DNA binding
LFT48_20390	COG3387	PFAM Glycoside hydrolase 15-related
LFT48_20400	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
LFT48_20405	COG0477	Major facilitator Superfamily
LFT48_20410	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LFT48_20415	COG1063	alcohol dehydrogenase
LFT48_20420	COG1028	Short-chain dehydrogenase reductase Sdr
LFT48_20425	COG0800	Aldolase
LFT48_20435	COG1414	Transcriptional regulator
LFT48_20440	COG0076	glutamate decarboxylase activity
LFT48_20465	COG4948	Mandelate Racemase Muconate Lactonizing
LFT48_20485	COG2814	Major facilitator Superfamily
LFT48_20525	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LFT48_20540	COG0471	metal ion transport
LFT48_20540	COG0490	domain, Protein
LFT48_20545	COG0477	Major facilitator Superfamily
LFT48_20550	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LFT48_20560	COG2261	transglycosylase associated protein
LFT48_20565	COG2815	serine threonine protein kinase
LFT48_20565	COG0515	serine threonine protein kinase
LFT48_20575	COG1846	Transcriptional regulator
LFT48_20605	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LFT48_20615	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LFT48_20620	COG0509	glycine decarboxylation via glycine cleavage system
LFT48_20625	COG0404	The glycine cleavage system catalyzes the degradation of glycine
LFT48_20630	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LFT48_20630	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LFT48_20645	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
LFT48_20650	COG1012	belongs to the aldehyde dehydrogenase family
LFT48_20660	COG1970	mechanosensitive ion channel activity
LFT48_20720	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LFT48_20750	COG2814	Major facilitator Superfamily
LFT48_20775	COG0179	Fumarylacetoacetate (FAA) hydrolase
LFT48_20780	COG0251	oxidation-reduction process
LFT48_20790	COG1414	Transcriptional regulator
LFT48_20795	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LFT48_20805	COG0183	Belongs to the thiolase family
LFT48_20810	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LFT48_20815	COG2267	carboxylic ester hydrolase activity
LFT48_20830	COG3485	protocatechuate 3,4-dioxygenase
LFT48_20840	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LFT48_20845	COG1414	Transcriptional regulator
LFT48_20850	COG0477	Major facilitator Superfamily
LFT48_20865	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
LFT48_20875	COG3706	GGDEF domain
LFT48_20885	COG0583	DNA-binding transcription factor activity
LFT48_20905	COG0463	Glycosyl transferase, family 2
LFT48_20925	COG2326	polyphosphate kinase activity
LFT48_20940	COG1737	Transcriptional regulator
LFT48_20945	COG3876	Protein conserved in bacteria
LFT48_20950	COG1472	Belongs to the glycosyl hydrolase 3 family
LFT48_20970	COG1937	Protein conserved in bacteria
LFT48_20975	COG2217	Heavy metal translocating P-type atpase
LFT48_21040	COG0534	Mate efflux family protein
LFT48_21050	COG2259	Doxx family
LFT48_21055	COG1607	acyl-coa hydrolase
LFT48_21070	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LFT48_21080	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LFT48_21085	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
LFT48_21090	COG0297	glycogen (starch) synthase activity
LFT48_21140	COG0489	protein tyrosine kinase activity
LFT48_21145	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LFT48_21165	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
LFT48_21170	COG0305	Participates in initiation and elongation during chromosome replication
LFT48_21210	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LFT48_21215	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LFT48_21240	COG2755	lipolytic protein G-D-S-L family
LFT48_21240	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
LFT48_21250	COG1131	(ABC) transporter
LFT48_21270	COG0359	binds to the 23S rRNA
LFT48_21275	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LFT48_21285	COG0360	Binds together with S18 to 16S ribosomal RNA
LFT48_21290	COG1742	UPF0060 membrane protein
LFT48_21305	COG1113	amino acid transport
LFT48_21310	COG1362	aminopeptidase activity
LFT48_21340	COG0833	amino acid
LFT48_21355	COG2197	response regulator
LFT48_21360	COG4585	Histidine kinase
LFT48_21370	COG1131	(ABC) transporter
LFT48_21375	COG1597	lipid kinase activity
LFT48_21385	COG0738	Major facilitator superfamily
LFT48_21395	COG0488	(ABC) transporter
LFT48_21400	COG0768	penicillin binding
LFT48_21405	COG1501	Belongs to the glycosyl hydrolase 31 family
LFT48_21410	COG2197	response regulator
LFT48_21415	COG4585	Histidine kinase
LFT48_21425	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LFT48_21430	COG1733	regulation of RNA biosynthetic process
LFT48_21435	COG2910	NAD(P)H-binding
LFT48_21455	COG0406	alpha-ribazole phosphatase activity
LFT48_21460	COG0617	tRNA 3'-terminal CCA addition
LFT48_21480	COG0492	ferredoxin-NADP+ reductase activity
LFT48_21485	COG3118	belongs to the thioredoxin family
LFT48_21495	COG1192	Involved in chromosome partitioning
LFT48_21500	COG0357	Ribosomal RNA small subunit methyltransferase G
LFT48_21510	COG0706	membrane insertase activity
LFT48_21515	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
LFT48_21520	COG0594	ribonuclease P activity
LFT48_21525	COG0230	Belongs to the bacterial ribosomal protein bL34 family
LFT48_21545	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LFT48_21550	COG0739	heme binding
LFT48_21570	COG0640	Transcriptional regulator
LFT48_21575	COG3336	cytochrome c oxidase
LFT48_21630	COG2354	Protein conserved in bacteria
LFT48_21635	COG1309	transcriptional regulator
LFT48_21650	COG0318	PFAM AMP-dependent synthetase and ligase
LFT48_21655	COG3842	ATPase activity
LFT48_21700	COG0489	protein tyrosine kinase activity
LFT48_21805	COG1609	Transcriptional regulator
LFT48_21810	COG2271	Major facilitator Superfamily
LFT48_21815	COG1304	FMN binding
LFT48_21825	COG0601	transmembrane transport
LFT48_21830	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LFT48_21835	COG0444	Belongs to the ABC transporter superfamily
LFT48_21840	COG4608	Belongs to the ABC transporter superfamily
LFT48_21850	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
LFT48_21870	COG3246	L-lysine catabolic process to acetate
LFT48_21875	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LFT48_21885	COG2084	Dehydrogenase
LFT48_21890	COG1082	Xylose isomerase domain protein TIM barrel
LFT48_21895	COG0149	triose-phosphate isomerase activity
LFT48_21900	COG0698	ribose 5-phosphate isomerase
LFT48_21905	COG2376	Dihydroxyacetone kinase
LFT48_21915	COG0477	Major facilitator Superfamily
LFT48_21920	COG2186	Transcriptional regulator
LFT48_21940	COG1012	belongs to the aldehyde dehydrogenase family
LFT48_21945	COG1129	ABC transporter
LFT48_21950	COG1172	Belongs to the binding-protein-dependent transport system permease family
LFT48_21955	COG1879	ABC-type sugar transport system periplasmic component
LFT48_21975	COG2186	Transcriptional regulator
LFT48_22060	COG1475	DNA binding
LFT48_22130	COG0789	Transcriptional regulator
LFT48_22145	COG2217	Heavy metal translocating P-type atpase
LFT48_22180	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LFT48_22200	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
LFT48_22205	COG1793	dna ligase
LFT48_22225	COG1401	restriction endodeoxyribonuclease activity
LFT48_22320	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins