locus-tag	class	description
LFT47_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LFT47_00010	COG0592	DNA-directed DNA polymerase activity
LFT47_00015	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
LFT47_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LFT47_00025	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
LFT47_00030	COG0187	DNA topoisomerase II activity
LFT47_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LFT47_00040	COG3266	domain, Protein
LFT47_00065	COG1215	transferase activity, transferring glycosyl groups
LFT47_00105	COG0640	Transcriptional regulator
LFT47_00110	COG2818	Glycosylase
LFT47_00120	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LFT47_00130	COG3764	Sortase (surface protein transpeptidase)
LFT47_00140	COG0515	serine threonine protein kinase
LFT47_00140	COG2815	serine threonine protein kinase
LFT47_00145	COG0515	serine threonine protein kinase
LFT47_00150	COG0768	penicillin binding
LFT47_00165	COG1716	ATPase activity
LFT47_00190	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
LFT47_00195	COG1984	allophanate hydrolase subunit 2
LFT47_00200	COG4770	biotin carboxylase activity
LFT47_00235	COG1609	Transcriptional regulator
LFT47_00240	COG0659	secondary active sulfate transmembrane transporter activity
LFT47_00270	COG0561	phosphatase activity
LFT47_00300	COG4941	Belongs to the sigma-70 factor family
LFT47_00310	COG1929	Belongs to the glycerate kinase type-1 family
LFT47_00320	COG2233	PERMEase
LFT47_00325	COG0778	Nitroreductase
LFT47_00345	COG3104	oligopeptide transport
LFT47_00350	COG0154	amidase activity
LFT47_00355	COG3340	Belongs to the peptidase S51 family
LFT47_00360	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LFT47_00360	COG0425	Belongs to the sulfur carrier protein TusA family
LFT47_00375	COG1597	lipid kinase activity
LFT47_00380	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LFT47_00390	COG0561	phosphatase activity
LFT47_00410	COG2027	D-alanyl-D-alanine carboxypeptidase
LFT47_00420	COG0037	tRNA processing
LFT47_00455	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LFT47_00460	COG0302	gtp cyclohydrolase
LFT47_00470	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LFT47_00500	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LFT47_00505	COG2814	Major facilitator Superfamily
LFT47_00525	COG1802	Transcriptional regulator
LFT47_00530	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LFT47_00535	COG1960	acyl-CoA dehydrogenase activity
LFT47_00565	COG0596	Alpha beta hydrolase
LFT47_00570	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
LFT47_00590	COG1506	peptidase
LFT47_00590	COG0823	Involved in the tonB-independent uptake of proteins
LFT47_00595	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
LFT47_00600	COG2376	Dihydroxyacetone kinase
LFT47_00605	COG1461	Dihydroxyacetone kinase
LFT47_00620	COG2226	methyltransferase
LFT47_00635	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
LFT47_00640	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
LFT47_00680	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LFT47_00685	COG0306	phosphate transporter
LFT47_00705	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LFT47_00710	COG0586	Pfam SNARE associated Golgi protein
LFT47_00715	COG0831	urea catabolic process
LFT47_00720	COG0832	Belongs to the urease beta subunit family
LFT47_00725	COG0804	urea catabolic process
LFT47_00730	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
LFT47_00735	COG0830	nickel cation binding
LFT47_00740	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
LFT47_00745	COG0829	nickel cation binding
LFT47_00750	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
LFT47_00755	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
LFT47_00755	COG1796	DNA polymerase
LFT47_00770	COG0656	L-ascorbic acid biosynthetic process
LFT47_00780	COG0667	Aldo Keto reductase
LFT47_00785	COG0656	L-ascorbic acid biosynthetic process
LFT47_00805	COG3360	Dodecin
LFT47_00810	COG2271	Major facilitator Superfamily
LFT47_00815	COG0251	oxidation-reduction process
LFT47_00835	COG1012	belongs to the aldehyde dehydrogenase family
LFT47_00840	COG0583	DNA-binding transcription factor activity
LFT47_00845	COG2186	Transcriptional regulator
LFT47_00860	COG2084	Dehydrogenase
LFT47_00865	COG2610	gluconate transmembrane transporter activity
LFT47_00945	COG0300	oxidoreductase activity
LFT47_00970	COG1172	Belongs to the binding-protein-dependent transport system permease family
LFT47_00980	COG1012	belongs to the aldehyde dehydrogenase family
LFT47_00985	COG3962	Belongs to the TPP enzyme family
LFT47_00995	COG0673	inositol 2-dehydrogenase activity
LFT47_01010	COG0673	inositol 2-dehydrogenase activity
LFT47_01050	COG0542	response to heat
LFT47_01055	COG0346	lactoylglutathione lyase activity
LFT47_01060	COG5002	protein histidine kinase activity
LFT47_01065	COG0745	RESPONSE REGULATOR receiver
LFT47_01075	COG0477	Major facilitator Superfamily
LFT47_01080	COG2890	protein-(glutamine-N5) methyltransferase activity
LFT47_01100	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
LFT47_01115	COG3237	CsbD-like
LFT47_01140	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LFT47_01145	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LFT47_01145	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LFT47_01145	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LFT47_01155	COG1349	DNA-binding transcription factor activity
LFT47_01190	COG1129	ABC transporter
LFT47_01195	COG1172	Belongs to the binding-protein-dependent transport system permease family
LFT47_01220	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LFT47_01235	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LFT47_01270	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
LFT47_01275	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
LFT47_01280	COG1984	allophanate hydrolase subunit 2
LFT47_01285	COG2733	membrane
LFT47_01325	COG4122	O-methyltransferase activity
LFT47_01350	COG1028	Short-chain dehydrogenase reductase Sdr
LFT47_01355	COG3706	GGDEF domain
LFT47_01370	COG1175	transmembrane transport
LFT47_01375	COG0395	ABC-type sugar transport system, permease component
LFT47_01380	COG1609	Transcriptional regulator
LFT47_01415	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
LFT47_01440	COG0010	Belongs to the arginase family
LFT47_01445	COG2252	PERMEase
LFT47_01465	COG3848	Pyruvate phosphate dikinase
LFT47_01465	COG0574	Belongs to the PEP-utilizing enzyme family
LFT47_01475	COG1609	Transcriptional regulator
LFT47_01505	COG1302	Protein conserved in bacteria
LFT47_01535	COG0366	Alpha amylase catalytic
LFT47_01560	COG1609	Transcriptional regulator
LFT47_01580	COG2197	response regulator
LFT47_01585	COG4585	Histidine kinase
LFT47_01595	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LFT47_01605	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LFT47_01620	COG0415	Belongs to the DNA photolyase family
LFT47_01640	COG1024	Enoyl-CoA hydratase
LFT47_01650	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LFT47_01660	COG1609	Transcriptional regulator
LFT47_01670	COG1175	transmembrane transport
LFT47_01675	COG0395	ABC-type sugar transport system, permease component
LFT47_01685	COG0673	inositol 2-dehydrogenase activity
LFT47_01700	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LFT47_01720	COG0357	Ribosomal RNA small subunit methyltransferase G
LFT47_01720	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LFT47_01725	COG0191	fructose-bisphosphate aldolase activity
LFT47_01745	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LFT47_01760	COG1832	CoA-binding protein
LFT47_01770	COG2315	Protein conserved in bacteria
LFT47_01780	COG1653	transport
LFT47_01785	COG1175	transmembrane transport
LFT47_01790	COG0395	ABC-type sugar transport system, permease component
LFT47_01810	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LFT47_01815	COG0047	phosphoribosylformylglycinamidine synthase activity
LFT47_01855	COG1846	Transcriptional regulator
LFT47_01875	COG1131	(ABC) transporter
LFT47_01885	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LFT47_01900	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LFT47_01935	COG2135	peptidase activity
LFT47_02020	COG0739	heme binding
LFT47_02315	COG1012	belongs to the aldehyde dehydrogenase family
LFT47_02335	COG0739	heme binding
LFT47_02335	COG0741	lytic transglycosylase activity
LFT47_02335	COG1196	nuclear chromosome segregation
LFT47_02340	COG0386	Belongs to the glutathione peroxidase family
LFT47_02365	COG4166	transmembrane transport
LFT47_02375	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LFT47_02380	COG0444	Belongs to the ABC transporter superfamily
LFT47_02385	COG4608	Belongs to the ABC transporter superfamily
LFT47_02420	COG1309	transcriptional regulator
LFT47_02435	COG0477	Major facilitator Superfamily
LFT47_02440	COG0823	Involved in the tonB-independent uptake of proteins
LFT47_02450	COG0673	inositol 2-dehydrogenase activity
LFT47_02455	COG0673	inositol 2-dehydrogenase activity
LFT47_02465	COG0395	ABC-type sugar transport system, permease component
LFT47_02500	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
LFT47_02510	COG1476	TRANSCRIPTIONal
LFT47_02530	COG1131	(ABC) transporter
LFT47_02545	COG0343	queuine tRNA-ribosyltransferase activity
LFT47_02590	COG1960	acyl-CoA dehydrogenase activity
LFT47_02595	COG3254	rhamnose metabolic process
LFT47_02600	COG0477	Major facilitator Superfamily
LFT47_02605	COG1609	Transcriptional regulator
LFT47_02610	COG0673	inositol 2-dehydrogenase activity
LFT47_02635	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
LFT47_02645	COG0586	Pfam SNARE associated Golgi protein
LFT47_02660	COG0564	pseudouridine synthase activity
LFT47_02695	COG2364	Membrane
LFT47_02700	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LFT47_02705	COG1201	RNA secondary structure unwinding
LFT47_02730	COG0475	glutathione-regulated potassium exporter activity
LFT47_02730	COG0569	domain protein
LFT47_02800	COG1846	Transcriptional regulator
LFT47_02820	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LFT47_02850	COG1621	beta-fructofuranosidase activity
LFT47_02865	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LFT47_02905	COG1254	Belongs to the acylphosphatase family
LFT47_02930	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LFT47_02935	COG1309	transcriptional regulator
LFT47_02940	COG0477	Major facilitator Superfamily
LFT47_02955	COG1609	Transcriptional regulator
LFT47_02965	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LFT47_02975	COG0363	glucosamine-6-phosphate deaminase activity
LFT47_02990	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LFT47_02995	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LFT47_03010	COG2205	protein histidine kinase activity
LFT47_03015	COG0745	RESPONSE REGULATOR receiver
LFT47_03040	COG0697	spore germination
LFT47_03050	COG1309	transcriptional regulator
LFT47_03055	COG1511	domain protein
LFT47_03070	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
LFT47_03075	COG1940	carbohydrate kinase activity
LFT47_03085	COG4608	Belongs to the ABC transporter superfamily
LFT47_03090	COG0444	Belongs to the ABC transporter superfamily
LFT47_03095	COG0601	transmembrane transport
LFT47_03100	COG0747	negative chemotaxis
LFT47_03105	COG2188	Transcriptional regulator
LFT47_03115	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
LFT47_03120	COG0574	Belongs to the PEP-utilizing enzyme family
LFT47_03120	COG3848	Pyruvate phosphate dikinase
LFT47_03140	COG0514	ATP-dependent DNA helicase (RecQ)
LFT47_03145	COG2814	Major facilitator Superfamily
LFT47_03160	COG1505	serine-type exopeptidase activity
LFT47_03180	COG1968	undecaprenyl-diphosphatase activity
LFT47_03185	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LFT47_03195	COG0604	alcohol dehydrogenase
LFT47_03220	COG0656	L-ascorbic acid biosynthetic process
LFT47_03225	COG1609	Transcriptional regulator
LFT47_03235	COG1175	transmembrane transport
LFT47_03240	COG0395	ABC-type sugar transport system, permease component
LFT47_03250	COG0673	inositol 2-dehydrogenase activity
LFT47_03275	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LFT47_03340	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LFT47_03345	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LFT47_03365	COG0588	phosphoglycerate mutase activity
LFT47_03395	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
LFT47_03400	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
LFT47_03405	COG0215	cysteine-tRNA ligase activity
LFT47_03410	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LFT47_03435	COG0366	Alpha amylase catalytic
LFT47_03440	COG0366	Alpha amylase catalytic
LFT47_03445	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LFT47_03480	COG0277	FAD linked oxidase domain protein
LFT47_03490	COG0402	S-adenosylhomocysteine deaminase activity
LFT47_03495	COG4608	Belongs to the ABC transporter superfamily
LFT47_03500	COG0444	Belongs to the ABC transporter superfamily
LFT47_03505	COG0601	transmembrane transport
LFT47_03515	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LFT47_03530	COG3842	ATPase activity
LFT47_03555	COG2508	Transcriptional regulator
LFT47_03600	COG0656	L-ascorbic acid biosynthetic process
LFT47_03610	COG1129	ABC transporter
LFT47_03615	COG1172	Belongs to the binding-protein-dependent transport system permease family
LFT47_03635	COG0698	ribose 5-phosphate isomerase
LFT47_03645	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LFT47_03650	COG1028	Short-chain dehydrogenase reductase Sdr
LFT47_03650	COG3347	Dehydrogenase
LFT47_03665	COG1172	Belongs to the binding-protein-dependent transport system permease family
LFT47_03670	COG1129	ABC transporter
LFT47_03680	COG1070	Carbohydrate kinase
LFT47_03685	COG1349	DNA-binding transcription factor activity
LFT47_03710	COG1940	carbohydrate kinase activity
LFT47_03715	COG1172	Belongs to the binding-protein-dependent transport system permease family
LFT47_03720	COG3457	Alanine racemase
LFT47_03730	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LFT47_03735	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LFT47_03750	COG3511	phospholipase C
LFT47_03755	COG0671	phosphoesterase, PA-phosphatase related
LFT47_03775	COG0454	-acetyltransferase
LFT47_03785	COG5001	Diguanylate cyclase
LFT47_03795	COG1940	carbohydrate kinase activity
LFT47_03795	COG1846	Transcriptional regulator
LFT47_03800	COG0366	Alpha amylase catalytic
LFT47_03810	COG1175	transmembrane transport
LFT47_03815	COG0395	ABC-type sugar transport system, permease component
LFT47_03830	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LFT47_03840	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LFT47_03850	COG0444	Belongs to the ABC transporter superfamily
LFT47_03875	COG4166	transmembrane transport
LFT47_03880	COG1335	isochorismatase
LFT47_03925	COG0402	S-adenosylhomocysteine deaminase activity
LFT47_03935	COG0154	amidase activity
LFT47_03940	COG3290	protein histidine kinase activity
LFT47_03945	COG4565	transcriptional regulatory protein
LFT47_03955	COG3832	glyoxalase III activity
LFT47_03960	COG0640	Transcriptional regulator
LFT47_03985	COG1177	transmembrane transport
LFT47_03990	COG3842	ATPase activity
LFT47_03995	COG0483	inositol monophosphate 1-phosphatase activity
LFT47_04030	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LFT47_04045	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LFT47_04065	COG1815	bacterial-type flagellum-dependent cell motility
LFT47_04075	COG1677	Flagellar hook-basal body complex protein FliE
LFT47_04080	COG1766	The M ring may be actively involved in energy transduction
LFT47_04085	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LFT47_04095	COG1157	protein secretion by the type III secretion system
LFT47_04115	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
LFT47_04135	COG0604	alcohol dehydrogenase
LFT47_04150	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
LFT47_04155	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LFT47_04160	COG0531	amino acid
LFT47_04165	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LFT47_04175	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
LFT47_04195	COG0671	phosphoesterase, PA-phosphatase related
LFT47_04210	COG5002	protein histidine kinase activity
LFT47_04240	COG3842	ATPase activity
LFT47_04260	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
LFT47_04265	COG1360	Flagellar Motor Protein
LFT47_04275	COG3585	molybdate ion transport
LFT47_04305	COG1338	Plays a role in the flagellum-specific transport system
LFT47_04320	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LFT47_04325	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LFT47_04335	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
LFT47_04350	COG0477	Major facilitator Superfamily
LFT47_04360	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LFT47_04360	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LFT47_04365	COG0404	The glycine cleavage system catalyzes the degradation of glycine
LFT47_04370	COG0509	glycine decarboxylation via glycine cleavage system
LFT47_04375	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LFT47_04385	COG1017	nitric oxide dioxygenase activity
LFT47_04385	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LFT47_04435	COG0459	protein refolding
LFT47_04440	COG0328	RNA-DNA hybrid ribonuclease activity
LFT47_04450	COG2205	protein histidine kinase activity
LFT47_04455	COG0745	RESPONSE REGULATOR receiver
LFT47_04490	COG1278	Cold shock
LFT47_04500	COG2814	Major facilitator Superfamily
LFT47_04515	COG0739	heme binding
LFT47_04530	COG0746	molybdenum cofactor guanylyltransferase activity
LFT47_04550	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LFT47_04560	COG1126	abc transporter atp-binding protein
LFT47_04565	COG0765	amino acid transport
LFT47_04570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LFT47_04585	COG0488	(ABC) transporter
LFT47_04590	COG1132	(ABC) transporter
LFT47_04655	COG0483	inositol monophosphate 1-phosphatase activity
LFT47_04660	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LFT47_04715	COG0045	succinate-CoA ligase (ADP-forming) activity
LFT47_04725	COG1942	4-Oxalocrotonate Tautomerase
LFT47_04740	COG3962	Belongs to the TPP enzyme family
LFT47_04755	COG0673	inositol 2-dehydrogenase activity
LFT47_04760	COG1082	Xylose isomerase domain protein TIM barrel
LFT47_04770	COG0659	secondary active sulfate transmembrane transporter activity
LFT47_04790	COG1609	Transcriptional regulator
LFT47_04800	COG1172	Belongs to the binding-protein-dependent transport system permease family
LFT47_04810	COG0673	inositol 2-dehydrogenase activity
LFT47_04815	COG0673	inositol 2-dehydrogenase activity
LFT47_04820	COG0673	inositol 2-dehydrogenase activity
LFT47_04830	COG0673	inositol 2-dehydrogenase activity
LFT47_04835	COG3718	enzyme involved in inositol metabolism
LFT47_04840	COG2188	Transcriptional regulator
LFT47_04855	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
LFT47_04875	COG0477	Major facilitator Superfamily
LFT47_04885	COG4176	ABC-type proline glycine betaine transport system permease component
LFT47_04890	COG4175	Glycine betaine
LFT47_04890	COG0517	IMP dehydrogenase activity
LFT47_04895	COG1012	belongs to the aldehyde dehydrogenase family
LFT47_04915	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LFT47_04930	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LFT47_04950	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LFT47_04975	COG1760	l-serine dehydratase
LFT47_04995	COG0726	polysaccharide deacetylase
LFT47_05025	COG1396	sequence-specific DNA binding
LFT47_05055	COG0028	Belongs to the TPP enzyme family
LFT47_05065	COG0477	Major facilitator Superfamily
LFT47_05085	COG3142	Participates in the control of copper homeostasis
LFT47_05095	COG1401	restriction endodeoxyribonuclease activity
LFT47_05115	COG5002	protein histidine kinase activity
LFT47_05120	COG0745	RESPONSE REGULATOR receiver
LFT47_05130	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
LFT47_05150	COG1902	pentaerythritol trinitrate reductase activity
LFT47_05165	COG2376	Dihydroxyacetone kinase
LFT47_05170	COG0698	ribose 5-phosphate isomerase
LFT47_05175	COG1250	3-hydroxyacyl-CoA dehydrogenase
LFT47_05180	COG1028	Short-chain dehydrogenase reductase Sdr
LFT47_05185	COG2271	Major facilitator Superfamily
LFT47_05190	COG0149	triose-phosphate isomerase activity
LFT47_05225	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LFT47_05250	COG0640	Transcriptional regulator
LFT47_05280	COG1309	transcriptional regulator
LFT47_05290	COG0477	Major facilitator Superfamily
LFT47_05310	COG0531	amino acid
LFT47_05320	COG1396	sequence-specific DNA binding
LFT47_05335	COG4565	transcriptional regulatory protein
LFT47_05340	COG1116	anion transmembrane transporter activity
LFT47_05345	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LFT47_05360	COG0667	Aldo Keto reductase
LFT47_05405	COG1205	dead DEAH box helicase
LFT47_05405	COG1111	helicase
LFT47_05415	COG1002	Type II restriction enzyme, methylase subunits
LFT47_05420	COG1401	restriction endodeoxyribonuclease activity
LFT47_05595	COG1131	(ABC) transporter
LFT47_05625	COG1116	anion transmembrane transporter activity
LFT47_05655	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LFT47_05675	COG2268	Band 7 protein
LFT47_05680	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LFT47_05685	COG2814	Major facilitator Superfamily
LFT47_05700	COG0179	Fumarylacetoacetate (FAA) hydrolase
LFT47_05730	COG2271	Major facilitator Superfamily
LFT47_05735	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
LFT47_05745	COG0138	bifunctional purine biosynthesis protein purh
LFT47_05760	COG2838	Isocitrate dehydrogenase
LFT47_05765	COG3639	organic phosphonate transmembrane transporter activity
LFT47_05780	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LFT47_05815	COG0673	inositol 2-dehydrogenase activity
LFT47_05820	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
LFT47_05825	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
LFT47_05830	COG3639	organic phosphonate transmembrane transporter activity
LFT47_05835	COG1136	(ABC) transporter
LFT47_05840	COG1136	(ABC) transporter
LFT47_05840	COG0577	efflux transmembrane transporter activity
LFT47_05885	COG1131	(ABC) transporter
LFT47_05900	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LFT47_05905	COG0531	amino acid
LFT47_05935	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LFT47_05940	COG4585	Histidine kinase
LFT47_05945	COG2197	response regulator
LFT47_05955	COG1131	(ABC) transporter
LFT47_05980	COG0180	Tryptophanyl-tRNA synthetase
LFT47_06000	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LFT47_06015	COG2009	succinate dehydrogenase
LFT47_06025	COG1473	amidohydrolase
LFT47_06025	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
LFT47_06030	COG1846	Transcriptional regulator
LFT47_06035	COG1764	response to oxidative stress
LFT47_06040	COG2130	NADP-dependent
LFT47_06045	COG1744	ABC transporter substrate-binding protein PnrA-like
LFT47_06050	COG3845	ABC transporter
LFT47_06055	COG4603	Belongs to the binding-protein-dependent transport system permease family
LFT47_06060	COG1079	Belongs to the binding-protein-dependent transport system permease family
LFT47_06075	COG0586	Pfam SNARE associated Golgi protein
LFT47_06080	COG0586	Pfam SNARE associated Golgi protein
LFT47_06085	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LFT47_06090	COG3956	TIGRFAM MazG family protein
LFT47_06095	COG0148	phosphopyruvate hydratase activity
LFT47_06120	COG1252	NADH dehydrogenase
LFT47_06150	COG0411	ABC transporter
LFT47_06165	COG0183	Belongs to the thiolase family
LFT47_06170	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LFT47_06180	COG2017	converts alpha-aldose to the beta-anomer
LFT47_06190	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LFT47_06195	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LFT47_06205	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LFT47_06215	COG1331	Highly conserved protein containing a thioredoxin domain
LFT47_06225	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LFT47_06230	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
LFT47_06270	COG0114	fumarate hydratase activity
LFT47_06275	COG0288	reversible hydration of carbon dioxide
LFT47_06285	COG1494	fructose-1,6-bisphosphatase
LFT47_06300	COG1482	cell wall glycoprotein biosynthetic process
LFT47_06305	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LFT47_06355	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
LFT47_06365	COG1376	ErfK ybiS ycfS ynhG family protein
LFT47_06410	COG0714	Associated with various cellular activities
LFT47_06415	COG0084	hydrolase, TatD family'
LFT47_06420	COG3583	domain protein
LFT47_06425	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LFT47_06430	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LFT47_06435	COG0488	(ABC) transporter
LFT47_06440	COG1309	transcriptional regulator
LFT47_06450	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LFT47_06460	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
LFT47_06465	COG0193	aminoacyl-tRNA hydrolase activity
LFT47_06490	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LFT47_06500	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LFT47_06510	COG3979	chitinase
LFT47_06520	COG1215	transferase activity, transferring glycosyl groups
LFT47_06555	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LFT47_06575	COG1988	membrane-bound metal-dependent
LFT47_06605	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LFT47_06610	COG0446	pyridine nucleotide-disulphide oxidoreductase
LFT47_06620	COG2814	Major facilitator Superfamily
LFT47_06630	COG1648	precorrin-2 dehydrogenase activity
LFT47_06630	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LFT47_06635	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LFT47_06635	COG2146	nitrite reductase [NAD(P)H] activity
LFT47_06645	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LFT47_06650	COG1621	beta-fructofuranosidase activity
LFT47_06675	COG1136	(ABC) transporter
LFT47_06740	COG0243	molybdopterin cofactor binding
LFT47_06745	COG2223	nitrite transmembrane transporter activity
LFT47_06750	COG0477	Major facilitator Superfamily
LFT47_06755	COG4770	biotin carboxylase activity
LFT47_06760	COG0424	maF-like protein
LFT47_06765	COG2409	Drug exporters of the RND superfamily
LFT47_06770	COG1309	transcriptional regulator
LFT47_06775	COG0393	Putative heavy-metal-binding
LFT47_06780	COG1823	symporter activity
LFT47_06795	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LFT47_06800	COG1028	Short-chain dehydrogenase reductase Sdr
LFT47_06830	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LFT47_06835	COG0483	inositol monophosphate 1-phosphatase activity
LFT47_06840	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LFT47_06845	COG0456	acetyltransferase
LFT47_06850	COG0251	oxidation-reduction process
LFT47_06855	COG4565	transcriptional regulatory protein
LFT47_06860	COG3290	protein histidine kinase activity
LFT47_06865	COG2851	Citrate transporter
LFT47_06870	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LFT47_06875	COG0154	amidase activity
LFT47_06880	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LFT47_06890	COG1609	Transcriptional regulator
LFT47_06900	COG1175	transmembrane transport
LFT47_06905	COG0395	ABC-type sugar transport system, permease component
LFT47_06925	COG1063	alcohol dehydrogenase
LFT47_06930	COG0156	8-amino-7-oxononanoate synthase activity
LFT47_06935	COG1486	melibiose metabolic process
LFT47_06950	COG1228	amidohydrolase
LFT47_06960	COG1940	carbohydrate kinase activity
LFT47_06960	COG1846	Transcriptional regulator
LFT47_06980	COG0588	phosphoglycerate mutase activity
LFT47_06995	COG2873	o-acetylhomoserine
LFT47_07000	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LFT47_07030	COG0423	glycine-tRNA ligase activity
LFT47_07050	COG1131	(ABC) transporter
LFT47_07055	COG0842	Transport permease protein
LFT47_07060	COG4585	Histidine kinase
LFT47_07065	COG2197	response regulator
LFT47_07080	COG0358	DNA primase activity
LFT47_07095	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LFT47_07125	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LFT47_07135	COG0297	glycogen (starch) synthase activity
LFT47_07185	COG0052	Belongs to the universal ribosomal protein uS2 family
LFT47_07190	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LFT47_07195	COG0528	UMP kinase activity
LFT47_07200	COG0233	cytoplasmic translational termination
LFT47_07205	COG0575	Belongs to the CDS family
LFT47_07215	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LFT47_07230	COG3275	phosphorelay sensor kinase activity
LFT47_07240	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LFT47_07255	COG1522	sequence-specific DNA binding
LFT47_07265	COG0022	dehydrogenase e1 component
LFT47_07270	COG0508	dehydrogenase complex catalyzes the overall conversion of
LFT47_07280	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LFT47_07290	COG1960	acyl-CoA dehydrogenase activity
LFT47_07320	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
LFT47_07325	COG0750	zinc metalloprotease
LFT47_07335	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
LFT47_07345	COG1309	transcriptional regulator
LFT47_07355	COG1131	(ABC) transporter
LFT47_07360	COG0442	prolyl-tRNA aminoacylation
LFT47_07370	COG0076	glutamate decarboxylase activity
LFT47_07390	COG0779	Required for maturation of 30S ribosomal subunits
LFT47_07395	COG0195	Participates in both transcription termination and antitermination
LFT47_07405	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LFT47_07405	COG0481	GTPase activity
LFT47_07410	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LFT47_07415	COG0590	tRNA wobble adenosine to inosine editing
LFT47_07420	COG0436	Aminotransferase
LFT47_07425	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LFT47_07445	COG3483	tryptophan 2,3-dioxygenase activity
LFT47_07450	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LFT47_07455	COG1185	polyribonucleotide nucleotidyltransferase activity
LFT47_07460	COG0612	Peptidase, M16
LFT47_07485	COG0745	RESPONSE REGULATOR receiver
LFT47_07490	COG5002	protein histidine kinase activity
LFT47_07505	COG0315	cyclic pyranopterin monophosphate synthase activity
LFT47_07510	COG0521	Mo-molybdopterin cofactor biosynthetic process
LFT47_07520	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
LFT47_07540	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LFT47_07545	COG1674	ftsk spoiiie
LFT47_07555	COG1546	Belongs to the CinA family
LFT47_07555	COG1058	Belongs to the CinA family
LFT47_07560	COG1396	sequence-specific DNA binding
LFT47_07575	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LFT47_07580	COG2137	regulation of response to DNA damage stimulus
LFT47_07590	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LFT47_07595	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LFT47_07600	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LFT47_07605	COG2813	Specifically methylates the guanine in position
LFT47_07610	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LFT47_07620	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LFT47_07630	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LFT47_07635	COG0131	Imidazoleglycerol-phosphate dehydratase
LFT47_07640	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LFT47_07650	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LFT47_07670	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LFT47_07675	COG0291	Belongs to the bacterial ribosomal protein bL35 family
LFT47_07680	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LFT47_07685	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LFT47_07695	COG2814	Major facilitator Superfamily
LFT47_07710	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
LFT47_07720	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LFT47_07725	COG0072	phenylalanine-tRNA ligase activity
LFT47_07725	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LFT47_07755	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LFT47_07760	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LFT47_07765	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LFT47_07770	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LFT47_07775	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LFT47_07780	COG1438	arginine binding
LFT47_07785	COG0137	argininosuccinate synthase activity
LFT47_07790	COG0165	Argininosuccinate lyase
LFT47_07805	COG2094	Belongs to the DNA glycosylase MPG family
LFT47_07820	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LFT47_07850	COG0647	UMP catabolic process
LFT47_07865	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LFT47_07870	COG0497	DNA recombination
LFT47_07875	COG0504	CTP synthase activity
LFT47_07880	COG0494	nUDIX hydrolase
LFT47_07905	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
LFT47_07910	COG2079	MmgE PrpD family protein
LFT47_07920	COG4565	transcriptional regulatory protein
LFT47_07925	COG3290	protein histidine kinase activity
LFT47_07930	COG1301	dicarboxylic acid transport
LFT47_07940	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LFT47_07945	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LFT47_07955	COG0287	Prephenate dehydrogenase
LFT47_07960	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
LFT47_07970	COG1160	GTP binding
LFT47_07985	COG2824	Alkylphosphonate utilization operon protein PhnA
LFT47_07995	COG2814	Major facilitator Superfamily
LFT47_08000	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LFT47_08005	COG0509	glycine decarboxylation via glycine cleavage system
LFT47_08010	COG1716	ATPase activity
LFT47_08030	COG1192	Involved in chromosome partitioning
LFT47_08035	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
LFT47_08045	COG1940	carbohydrate kinase activity
LFT47_08065	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
LFT47_08075	COG3942	CHAP domain
LFT47_08075	COG1388	LysM domain
LFT47_08085	COG0142	geranyltranstransferase activity
LFT47_08095	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LFT47_08105	COG2001	Belongs to the MraZ family
LFT47_08110	COG0275	rRNA processing
LFT47_08120	COG0768	penicillin binding
LFT47_08125	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LFT47_08135	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LFT47_08140	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LFT47_08145	COG0772	Belongs to the SEDS family
LFT47_08150	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LFT47_08155	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LFT47_08160	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
LFT47_08165	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LFT47_08175	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LFT47_08180	COG1799	cell septum assembly
LFT47_08195	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LFT47_08205	COG0587	DNA-directed DNA polymerase activity
LFT47_08220	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LFT47_08225	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LFT47_08230	COG1028	Short-chain dehydrogenase reductase Sdr
LFT47_08250	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
LFT47_08255	COG0174	glutamine synthetase
LFT47_08260	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
LFT47_08300	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LFT47_08305	COG0321	lipoyl(octanoyl) transferase activity
LFT47_08310	COG0515	serine threonine protein kinase
LFT47_08315	COG1090	epimerase
LFT47_08320	COG4946	Tricorn protease homolog
LFT47_08320	COG0793	Belongs to the peptidase S41A family
LFT47_08325	COG1764	response to oxidative stress
LFT47_08335	COG0508	dehydrogenase complex catalyzes the overall conversion of
LFT47_08340	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LFT47_08345	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LFT47_08365	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LFT47_08370	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LFT47_08405	COG1271	oxidase subunit
LFT47_08410	COG1294	oxidase, subunit
LFT47_08415	COG4988	ABC transporter
LFT47_08435	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LFT47_08455	COG1435	thymidine kinase activity
LFT47_08475	COG0756	dUTP diphosphatase activity
LFT47_08500	COG0569	domain protein
LFT47_08505	COG0531	amino acid
LFT47_08510	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LFT47_08515	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LFT47_08520	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LFT47_08535	COG0667	Aldo Keto reductase
LFT47_08545	COG1024	Enoyl-CoA hydratase
LFT47_08545	COG1250	3-hydroxyacyl-CoA dehydrogenase
LFT47_08550	COG0183	Belongs to the thiolase family
LFT47_08580	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LFT47_08595	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LFT47_08615	COG3135	benzoate transporter
LFT47_08625	COG0531	amino acid
LFT47_08665	COG3706	GGDEF domain
LFT47_08675	COG0242	peptide deformylase activity
LFT47_08680	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LFT47_08690	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LFT47_08710	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LFT47_08710	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LFT47_08715	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LFT47_08715	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LFT47_08720	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
LFT47_08725	COG0140	phosphoribosyl-ATP diphosphatase activity
LFT47_08730	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
LFT47_08735	COG0107	imidazoleglycerol-phosphate synthase activity
LFT47_08745	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LFT47_08765	COG0134	indole-3-glycerol-phosphate synthase activity
LFT47_08770	COG0133	tryptophan synthase activity
LFT47_08775	COG0159	tryptophan synthase activity
LFT47_08780	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LFT47_08785	COG0067	glutamate synthase
LFT47_08785	COG0069	glutamate synthase activity
LFT47_08785	COG0070	glutamate synthase
LFT47_08815	COG2186	Transcriptional regulator
LFT47_08845	COG1177	transmembrane transport
LFT47_08860	COG4948	Mandelate Racemase Muconate Lactonizing
LFT47_08865	COG3618	amidohydrolase
LFT47_08875	COG1028	Short-chain dehydrogenase reductase Sdr
LFT47_08925	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LFT47_08935	COG0183	Belongs to the thiolase family
LFT47_08955	COG1028	Short-chain dehydrogenase reductase Sdr
LFT47_08965	COG2814	Major facilitator Superfamily
LFT47_08975	COG1028	Short-chain dehydrogenase reductase Sdr
LFT47_08995	COG0667	Aldo Keto reductase
LFT47_09000	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
LFT47_09005	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
LFT47_09015	COG2188	Transcriptional regulator
LFT47_09020	COG1960	acyl-CoA dehydrogenase activity
LFT47_09025	COG1028	Short-chain dehydrogenase reductase Sdr
LFT47_09040	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LFT47_09045	COG0318	PFAM AMP-dependent synthetase and ligase
LFT47_09070	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
LFT47_09080	COG2186	Transcriptional regulator
LFT47_09120	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LFT47_09125	COG0444	Belongs to the ABC transporter superfamily
LFT47_09130	COG4608	Belongs to the ABC transporter superfamily
LFT47_09135	COG1028	Short-chain dehydrogenase reductase Sdr
LFT47_09160	COG4166	transmembrane transport
LFT47_09180	COG1802	Transcriptional regulator
LFT47_09205	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LFT47_09210	COG0444	Belongs to the ABC transporter superfamily
LFT47_09215	COG4608	Belongs to the ABC transporter superfamily
LFT47_09225	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
LFT47_09230	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
LFT47_09260	COG2072	flavoprotein involved in K transport
LFT47_09265	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LFT47_09270	COG1024	Enoyl-CoA hydratase
LFT47_09295	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
LFT47_09310	COG1024	Enoyl-CoA hydratase
LFT47_09325	COG0183	Belongs to the thiolase family
LFT47_09335	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
LFT47_09345	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LFT47_09350	COG1012	belongs to the aldehyde dehydrogenase family
LFT47_09360	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LFT47_09385	COG1012	belongs to the aldehyde dehydrogenase family
LFT47_09395	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LFT47_09395	COG0512	Glutamine amidotransferase of anthranilate synthase
LFT47_09405	COG1609	Transcriptional regulator
LFT47_09430	COG0667	Aldo Keto reductase
LFT47_09455	COG1028	Short-chain dehydrogenase reductase Sdr
LFT47_09460	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
LFT47_09475	COG1414	Transcriptional regulator
LFT47_09490	COG2814	Major facilitator Superfamily
LFT47_09510	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LFT47_09520	COG4638	Rieske (2fe-2S)
LFT47_09595	COG3654	unkown
LFT47_09605	COG0583	DNA-binding transcription factor activity
LFT47_09610	COG2828	Protein conserved in bacteria
LFT47_09615	COG1301	dicarboxylic acid transport
LFT47_09640	COG0800	Aldolase
LFT47_09650	COG1609	Transcriptional regulator
LFT47_09665	COG0673	inositol 2-dehydrogenase activity
LFT47_09670	COG1028	Short-chain dehydrogenase reductase Sdr
LFT47_09695	COG1309	transcriptional regulator
LFT47_09705	COG3321	synthase
LFT47_09705	COG0604	alcohol dehydrogenase
LFT47_09715	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
LFT47_09720	COG0154	amidase activity
LFT47_09725	COG1172	Belongs to the binding-protein-dependent transport system permease family
LFT47_09730	COG1129	ABC transporter
LFT47_09750	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LFT47_09755	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LFT47_09770	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LFT47_09775	COG0251	oxidation-reduction process
LFT47_09780	COG0477	Major facilitator Superfamily
LFT47_09790	COG0477	Major facilitator Superfamily
LFT47_09795	COG0028	Belongs to the TPP enzyme family
LFT47_09800	COG1012	belongs to the aldehyde dehydrogenase family
LFT47_09805	COG1574	metal-dependent hydrolase with the TIM-barrel fold
LFT47_09810	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LFT47_09830	COG0477	Major facilitator Superfamily
LFT47_09835	COG1063	alcohol dehydrogenase
LFT47_09840	COG0246	Mannitol dehydrogenase
LFT47_09845	COG4948	Mandelate Racemase Muconate Lactonizing
LFT47_09850	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LFT47_09855	COG1609	Transcriptional regulator
LFT47_09915	COG3654	unkown
LFT47_09920	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LFT47_09940	COG1621	beta-fructofuranosidase activity
LFT47_09945	COG0395	ABC-type sugar transport system, permease component
LFT47_09960	COG1609	Transcriptional regulator
LFT47_09980	COG0667	Aldo Keto reductase
LFT47_09995	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LFT47_10005	COG1335	isochorismatase
LFT47_10035	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LFT47_10040	COG0443	Heat shock 70 kDa protein
LFT47_10045	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LFT47_10060	COG0542	response to heat
LFT47_10070	COG0288	reversible hydration of carbon dioxide
LFT47_10075	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LFT47_10085	COG2200	EAL domain
LFT47_10095	COG1609	Transcriptional regulator
LFT47_10100	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LFT47_10105	COG0698	ribose 5-phosphate isomerase
LFT47_10110	COG0477	Major facilitator Superfamily
LFT47_10115	COG0667	Aldo Keto reductase
LFT47_10120	COG0667	Aldo Keto reductase
LFT47_10135	COG0515	serine threonine protein kinase
LFT47_10155	COG5416	Lipopolysaccharide assembly protein A domain
LFT47_10160	COG1295	ribonuclease BN
LFT47_10200	COG0484	heat shock protein binding
LFT47_10205	COG0071	Belongs to the small heat shock protein (HSP20) family
LFT47_10210	COG0789	Transcriptional regulator
LFT47_10215	COG1396	sequence-specific DNA binding
LFT47_10225	COG0667	Aldo Keto reductase
LFT47_10250	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LFT47_10280	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LFT47_10290	COG0688	phosphatidylethanolamine metabolic process
LFT47_10370	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
LFT47_10380	COG0543	2 iron, 2 sulfur cluster binding
LFT47_10380	COG0633	Ferredoxin
LFT47_10385	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LFT47_10415	COG3118	belongs to the thioredoxin family
LFT47_10420	COG0789	Transcriptional regulator
LFT47_10445	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LFT47_10450	COG0667	Aldo Keto reductase
LFT47_10460	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LFT47_10490	COG1131	(ABC) transporter
LFT47_10525	COG3795	YCII-related domain
LFT47_10530	COG4941	Belongs to the sigma-70 factor family
LFT47_10550	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LFT47_10595	COG1309	transcriptional regulator
LFT47_10605	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
LFT47_10630	COG4632	Exopolysaccharide biosynthesis protein
LFT47_10630	COG5434	Belongs to the glycosyl hydrolase 28 family
LFT47_10635	COG0598	Magnesium transport protein CorA
LFT47_10645	COG0318	PFAM AMP-dependent synthetase and ligase
LFT47_10695	COG3387	PFAM Glycoside hydrolase 15-related
LFT47_10705	COG1609	Transcriptional regulator
LFT47_10720	COG2160	L-arabinose isomerase activity
LFT47_10735	COG3534	alpha-L-arabinofuranosidase
LFT47_10740	COG0395	ABC-type sugar transport system, permease component
LFT47_10780	COG1012	belongs to the aldehyde dehydrogenase family
LFT47_10800	COG3226	Transcriptional regulator
LFT47_10810	COG4952	isomerase
LFT47_10815	COG3347	Dehydrogenase
LFT47_10815	COG1028	Short-chain dehydrogenase reductase Sdr
LFT47_10820	COG1070	Carbohydrate kinase
LFT47_10830	COG2814	Major facilitator Superfamily
LFT47_10875	COG1012	belongs to the aldehyde dehydrogenase family
LFT47_10880	COG1028	Short-chain dehydrogenase reductase Sdr
LFT47_10885	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LFT47_10890	COG1024	Enoyl-CoA hydratase
LFT47_10895	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LFT47_10905	COG1396	sequence-specific DNA binding
LFT47_10910	COG0477	Major facilitator Superfamily
LFT47_10920	COG3422	double-strand break repair
LFT47_10935	COG0515	serine threonine protein kinase
LFT47_10940	COG0405	Gamma-glutamyltransferase
LFT47_10960	COG3959	Transketolase, thiamine diphosphate binding domain
LFT47_10980	COG1028	Short-chain dehydrogenase reductase Sdr
LFT47_11045	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LFT47_11055	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LFT47_11065	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
LFT47_11085	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
LFT47_11090	COG0217	transcriptional regulatory protein
LFT47_11095	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
LFT47_11100	COG0632	four-way junction helicase activity
LFT47_11105	COG2255	four-way junction helicase activity
LFT47_11115	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LFT47_11120	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LFT47_11125	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LFT47_11135	COG1196	nuclear chromosome segregation
LFT47_11145	COG0124	histidyl-tRNA synthetase
LFT47_11150	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LFT47_11175	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LFT47_11190	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LFT47_11205	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LFT47_11210	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
LFT47_11215	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LFT47_11220	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LFT47_11230	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LFT47_11235	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LFT47_11240	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LFT47_11245	COG0540	Belongs to the ATCase OTCase family
LFT47_11250	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LFT47_11260	COG0505	Belongs to the CarA family
LFT47_11265	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LFT47_11270	COG0284	orotidine-5'-phosphate decarboxylase activity
LFT47_11280	COG0194	GDP metabolic process
LFT47_11285	COG1758	RNA polymerase activity
LFT47_11295	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LFT47_11305	COG0438	transferase activity, transferring glycosyl groups
LFT47_11315	COG0656	L-ascorbic acid biosynthetic process
LFT47_11320	COG2390	Transcriptional regulator
LFT47_11325	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LFT47_11330	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LFT47_11335	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LFT47_11340	COG0495	leucyl-tRNA aminoacylation
LFT47_11345	COG1307	EDD domain protein, DegV family
LFT47_11355	COG1555	photosystem II stabilization
LFT47_11440	COG0768	penicillin binding
LFT47_11450	COG0166	Belongs to the GPI family
LFT47_11500	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LFT47_11540	COG0268	Binds directly to 16S ribosomal RNA
LFT47_11550	COG0481	GTPase activity
LFT47_11555	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LFT47_11570	COG1420	regulation of RNA biosynthetic process
LFT47_11575	COG0484	heat shock protein binding
LFT47_11580	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LFT47_11595	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LFT47_11605	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LFT47_11610	COG1316	TRANSCRIPTIONal
LFT47_11615	COG3590	peptidase
LFT47_11620	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LFT47_11625	COG1381	Involved in DNA repair and RecF pathway recombination
LFT47_11630	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LFT47_11635	COG2267	carboxylic ester hydrolase activity
LFT47_11650	COG0167	dihydroorotate dehydrogenase activity
LFT47_11670	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LFT47_11675	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LFT47_11685	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LFT47_11690	COG2188	Transcriptional regulator
LFT47_11695	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LFT47_11700	COG0723	plastoquinol--plastocyanin reductase activity
LFT47_11705	COG2010	Cytochrome c
LFT47_11710	COG1845	cytochrome c oxidase, subunit III
LFT47_11715	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LFT47_11740	COG1316	TRANSCRIPTIONal
LFT47_11745	COG1280	lysine exporter protein (LysE YggA)
LFT47_11755	COG2197	response regulator
LFT47_11765	COG3559	Exporter of polyketide antibiotics
LFT47_11770	COG1131	(ABC) transporter
LFT47_11775	COG0596	Alpha beta hydrolase
LFT47_11790	COG1335	isochorismatase
LFT47_11800	COG0384	phenazine biosynthesis protein PhzF
LFT47_11810	COG4974	Belongs to the 'phage' integrase family
LFT47_11855	COG3424	synthase
LFT47_11860	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LFT47_11870	COG0242	peptide deformylase activity
LFT47_11875	COG1506	peptidase
LFT47_11875	COG0823	Involved in the tonB-independent uptake of proteins
LFT47_11875	COG4946	Tricorn protease homolog
LFT47_11900	COG1216	Glycosyl transferase, family 2
LFT47_11905	COG1574	metal-dependent hydrolase with the TIM-barrel fold
LFT47_11910	COG4581	dead DEAH box helicase
LFT47_11915	COG0805	protein transport
LFT47_11920	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LFT47_11940	COG0545	Peptidyl-prolyl cis-trans isomerase
LFT47_11945	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
LFT47_11950	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
LFT47_11955	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
LFT47_11965	COG4122	O-methyltransferase activity
LFT47_11970	COG1222	aaa ATPase
LFT47_11980	COG1994	Peptidase M50
LFT47_11980	COG0517	IMP dehydrogenase activity
LFT47_11985	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LFT47_11995	COG0215	cysteine-tRNA ligase activity
LFT47_12000	COG1968	undecaprenyl-diphosphatase activity
LFT47_12005	COG0656	L-ascorbic acid biosynthetic process
LFT47_12025	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LFT47_12040	COG1028	Short-chain dehydrogenase reductase Sdr
LFT47_12060	COG0297	glycogen (starch) synthase activity
LFT47_12065	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LFT47_12090	COG2855	membrane
LFT47_12115	COG0254	rRNA binding
LFT47_12130	COG1119	ATPase activity
LFT47_12135	COG3830	Belongs to the UPF0237 family
LFT47_12135	COG0560	Phosphoserine phosphatase
LFT47_12140	COG1028	Short-chain dehydrogenase reductase Sdr
LFT47_12145	COG1028	Short-chain dehydrogenase reductase Sdr
LFT47_12175	COG0488	(ABC) transporter
LFT47_12185	COG1268	BioY protein
LFT47_12190	COG1122	ATPase activity
LFT47_12205	COG0318	PFAM AMP-dependent synthetase and ligase
LFT47_12210	COG2151	metal-sulfur cluster biosynthetic enzyme
LFT47_12215	COG0396	ATPase activity
LFT47_12240	COG1131	(ABC) transporter
LFT47_12250	COG1612	heme a metabolic process
LFT47_12255	COG0109	protoheme IX farnesyltransferase activity
LFT47_12265	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LFT47_12270	COG0166	Belongs to the GPI family
LFT47_12285	COG0363	glucosamine-6-phosphate deaminase activity
LFT47_12295	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LFT47_12300	COG0149	triose-phosphate isomerase activity
LFT47_12305	COG0126	phosphoglycerate kinase activity
LFT47_12310	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LFT47_12315	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LFT47_12320	COG1481	regulation of sporulation
LFT47_12325	COG0391	Required for morphogenesis under gluconeogenic growth conditions
LFT47_12330	COG1660	Displays ATPase and GTPase activities
LFT47_12335	COG0322	excinuclease ABC activity
LFT47_12345	COG0546	phosphoglycolate phosphatase activity
LFT47_12370	COG4106	trans-aconitate 2-methyltransferase activity
LFT47_12390	COG2814	Major facilitator Superfamily
LFT47_12400	COG0556	nucleotide-excision repair
LFT47_12410	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LFT47_12410	COG0237	dephospho-CoA kinase activity
LFT47_12415	COG1739	Uncharacterized protein family UPF0029
LFT47_12420	COG0539	negative regulation of cytoplasmic translation
LFT47_12430	COG4552	Acetyltransferase involved in intracellular survival and related
LFT47_12440	COG2050	protein possibly involved in aromatic compounds catabolism
LFT47_12445	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LFT47_12465	COG3483	tryptophan 2,3-dioxygenase activity
LFT47_12500	COG0009	L-threonylcarbamoyladenylate synthase
LFT47_12520	COG1643	Atp-dependent helicase
LFT47_12555	COG1064	alcohol dehydrogenase
LFT47_12560	COG0477	Major facilitator Superfamily
LFT47_12565	COG1609	Transcriptional regulator
LFT47_12585	COG0492	ferredoxin-NADP+ reductase activity
LFT47_12600	COG2814	Major facilitator Superfamily
LFT47_12640	COG4804	nuclease activity
LFT47_12655	COG0412	Dienelactone hydrolase
LFT47_12660	COG1234	tRNA 3'-trailer cleavage
LFT47_12705	COG0667	Aldo Keto reductase
LFT47_12710	COG1501	Belongs to the glycosyl hydrolase 31 family
LFT47_12715	COG3387	PFAM Glycoside hydrolase 15-related
LFT47_12725	COG0395	ABC-type sugar transport system, permease component
LFT47_12730	COG1175	transmembrane transport
LFT47_12735	COG1846	Transcriptional regulator
LFT47_12735	COG1940	carbohydrate kinase activity
LFT47_12740	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LFT47_12745	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LFT47_12750	COG1780	Probably involved in ribonucleotide reductase function
LFT47_12760	COG0583	DNA-binding transcription factor activity
LFT47_12770	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LFT47_12775	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LFT47_12790	COG1175	transmembrane transport
LFT47_12795	COG1653	transport
LFT47_12840	COG1309	transcriptional regulator
LFT47_12845	COG1028	Short-chain dehydrogenase reductase Sdr
LFT47_12855	COG0477	Major facilitator Superfamily
LFT47_12860	COG1957	nucleoside hydrolase
LFT47_12870	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LFT47_12880	COG2957	Belongs to the agmatine deiminase family
LFT47_12885	COG0154	amidase activity
LFT47_12890	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LFT47_12910	COG0444	Belongs to the ABC transporter superfamily
LFT47_12950	COG0587	DNA-directed DNA polymerase activity
LFT47_12960	COG0673	inositol 2-dehydrogenase activity
LFT47_12975	COG1609	Transcriptional regulator
LFT47_13015	COG0799	negative regulation of ribosome biogenesis
LFT47_13025	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LFT47_13035	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LFT47_13040	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LFT47_13045	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LFT47_13050	COG0211	Belongs to the bacterial ribosomal protein bL27 family
LFT47_13055	COG0261	This protein binds to 23S rRNA in the presence of protein L20
LFT47_13060	COG0351	phosphomethylpyrimidine kinase
LFT47_13060	COG0352	thiamine-phosphate diphosphorylase activity
LFT47_13060	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LFT47_13065	COG1530	ribonuclease E activity
LFT47_13075	COG0105	UTP biosynthetic process
LFT47_13085	COG0285	dihydrofolate synthase activity
LFT47_13090	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LFT47_13105	COG0525	valine-tRNA ligase activity
LFT47_13110	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LFT47_13115	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
LFT47_13120	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LFT47_13125	COG0740	serine-type endopeptidase activity
LFT47_13130	COG0740	serine-type endopeptidase activity
LFT47_13135	COG0544	peptidyl-prolyl cis-trans isomerase activity
LFT47_13155	COG0698	ribose 5-phosphate isomerase
LFT47_13175	COG0668	transmembrane transport
LFT47_13190	COG1946	Acyl-CoA thioesterase
LFT47_13220	COG0024	Methionine aminopeptidase
LFT47_13260	COG0242	peptide deformylase activity
LFT47_13290	COG3022	response to hydroperoxide
LFT47_13300	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LFT47_13305	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LFT47_13315	COG1045	serine acetyltransferase
LFT47_13320	COG0300	oxidoreductase activity
LFT47_13325	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LFT47_13335	COG1063	alcohol dehydrogenase
LFT47_13340	COG1028	Short-chain dehydrogenase reductase Sdr
LFT47_13350	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LFT47_13355	COG0477	Major facilitator Superfamily
LFT47_13360	COG1414	Transcriptional regulator
LFT47_13370	COG2188	Transcriptional regulator
LFT47_13390	COG3842	ATPase activity
LFT47_13425	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
LFT47_13440	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LFT47_13445	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LFT47_13460	COG4974	Belongs to the 'phage' integrase family
LFT47_13475	COG0792	nuclease activity
LFT47_13485	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LFT47_13495	COG0681	Belongs to the peptidase S26 family
LFT47_13500	COG0335	large ribosomal subunit rRNA binding
LFT47_13505	COG0336	Belongs to the RNA methyltransferase TrmD family
LFT47_13510	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LFT47_13515	COG1837	Belongs to the UPF0109 family
LFT47_13520	COG0228	four-way junction DNA binding
LFT47_13530	COG2514	catechol 2,3-dioxygenase activity
LFT47_13555	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LFT47_13570	COG2814	Major facilitator Superfamily
LFT47_13585	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LFT47_13590	COG0571	ribonuclease III activity
LFT47_13595	COG0333	Belongs to the bacterial ribosomal protein bL32 family
LFT47_13605	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LFT47_13620	COG0742	ribosomal rna small subunit methyltransferase
LFT47_13645	COG1181	Belongs to the D-alanine--D-alanine ligase family
LFT47_13650	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
LFT47_13660	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LFT47_13665	COG0066	3-isopropylmalate dehydratase activity
LFT47_13670	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LFT47_13675	COG1414	Transcriptional regulator
LFT47_13705	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LFT47_13710	COG0179	Fumarylacetoacetate (FAA) hydrolase
LFT47_13715	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LFT47_13725	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LFT47_13730	COG0473	3-isopropylmalate dehydrogenase activity
LFT47_13755	COG1136	(ABC) transporter
LFT47_13755	COG0577	efflux transmembrane transporter activity
LFT47_13765	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LFT47_13770	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LFT47_13775	COG0440	acetolactate synthase activity
LFT47_13785	COG0129	dihydroxy-acid dehydratase activity
LFT47_13795	COG2133	pyrroloquinoline quinone binding
LFT47_13825	COG0747	negative chemotaxis
LFT47_13830	COG0579	oxidoreductase
LFT47_13835	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LFT47_13840	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LFT47_13850	COG1305	Transglutaminase-like
LFT47_13875	COG1104	cysteine desulfurase activity
LFT47_13885	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
LFT47_13890	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LFT47_13905	COG1113	amino acid transport
LFT47_13915	COG0022	dehydrogenase e1 component
LFT47_13920	COG0508	dehydrogenase complex catalyzes the overall conversion of
LFT47_13950	COG1414	Transcriptional regulator
LFT47_13960	COG0419	ATPase involved in DNA repair
LFT47_13965	COG0420	3'-5' exonuclease activity
LFT47_13970	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LFT47_13980	COG2149	membrane
LFT47_14010	COG0586	Pfam SNARE associated Golgi protein
LFT47_14015	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LFT47_14020	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
LFT47_14025	COG1234	tRNA 3'-trailer cleavage
LFT47_14030	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
LFT47_14040	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
LFT47_14050	COG1335	isochorismatase
LFT47_14065	COG0363	glucosamine-6-phosphate deaminase activity
LFT47_14080	COG1902	pentaerythritol trinitrate reductase activity
LFT47_14110	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
LFT47_14115	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LFT47_14125	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LFT47_14140	COG0355	proton-transporting ATP synthase activity, rotational mechanism
LFT47_14145	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LFT47_14150	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LFT47_14155	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LFT47_14160	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LFT47_14165	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LFT47_14170	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LFT47_14175	COG0356	it plays a direct role in the translocation of protons across the membrane
LFT47_14210	COG2890	protein-(glutamine-N5) methyltransferase activity
LFT47_14215	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LFT47_14225	COG0083	homoserine kinase activity
LFT47_14230	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LFT47_14235	COG0460	homoserine dehydrogenase
LFT47_14240	COG0019	diaminopimelate decarboxylase activity
LFT47_14245	COG0018	arginyl-trna synthetase
LFT47_14295	COG1643	Atp-dependent helicase
LFT47_14305	COG1064	alcohol dehydrogenase
LFT47_14330	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LFT47_14335	COG1121	(ABC) transporter
LFT47_14350	COG1253	flavin adenine dinucleotide binding
LFT47_14355	COG0508	dehydrogenase complex catalyzes the overall conversion of
LFT47_14355	COG0567	Dehydrogenase, E1 component
LFT47_14380	COG1595	DNA-templated transcription, initiation
LFT47_14390	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
LFT47_14400	COG0483	inositol monophosphate 1-phosphatase activity
LFT47_14405	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LFT47_14445	COG1028	Short-chain dehydrogenase reductase Sdr
LFT47_14455	COG1960	acyl-CoA dehydrogenase activity
LFT47_14465	COG0477	Major facilitator Superfamily
LFT47_14475	COG0701	Predicted permease
LFT47_14495	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
LFT47_14505	COG2177	Part of the ABC transporter FtsEX involved in
LFT47_14510	COG2884	Cell division ATP-binding protein ftsE
LFT47_14515	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
LFT47_14650	COG0463	Glycosyl transferase, family 2
LFT47_14660	COG0463	Glycosyl transferase, family 2
LFT47_14675	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
LFT47_14675	COG2755	lipolytic protein G-D-S-L family
LFT47_14700	COG1216	Glycosyl transferase, family 2
LFT47_14730	COG2902	Dehydrogenase
LFT47_14765	COG0653	protein targeting
LFT47_14770	COG3214	Protein conserved in bacteria
LFT47_14775	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LFT47_14785	COG5401	PFAM Sporulation and spore germination
LFT47_14790	COG5002	protein histidine kinase activity
LFT47_14815	COG0714	Associated with various cellular activities
LFT47_14850	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LFT47_14855	COG0601	transmembrane transport
LFT47_14865	COG0482	sulfurtransferase activity
LFT47_14890	COG0484	heat shock protein binding
LFT47_14895	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LFT47_14905	COG5343	regulation of RNA biosynthetic process
LFT47_14920	COG3265	gluconokinase activity
LFT47_14930	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
LFT47_14935	COG2086	electron transfer activity
LFT47_14940	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LFT47_14950	COG1842	Phage shock protein A
LFT47_14955	COG1960	acyl-CoA dehydrogenase activity
LFT47_14965	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
LFT47_15015	COG1615	UPF0182 protein
LFT47_15020	COG3480	Lon protease (S16) C-terminal proteolytic domain
LFT47_15040	COG2816	NAD+ diphosphatase activity
LFT47_15050	COG0210	DNA helicase
LFT47_15070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LFT47_15075	COG0765	amino acid transport
LFT47_15080	COG1126	abc transporter atp-binding protein
LFT47_15085	COG1472	Belongs to the glycosyl hydrolase 3 family
LFT47_15090	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
LFT47_15100	COG0113	porphobilinogen synthase activity
LFT47_15110	COG0181	hydroxymethylbilane synthase activity
LFT47_15115	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
LFT47_15120	COG3253	May function as heme-dependent peroxidase
LFT47_15130	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
LFT47_15135	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
LFT47_15165	COG2154	pterin-4-alpha-carbinolamine dehydratase
LFT47_15170	COG2022	thiamine diphosphate biosynthetic process
LFT47_15180	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LFT47_15180	COG2022	thiamine diphosphate biosynthetic process
LFT47_15185	COG0352	thiamine-phosphate diphosphorylase activity
LFT47_15190	COG0557	exoribonuclease II activity
LFT47_15195	COG0513	Belongs to the DEAD box helicase family
LFT47_15200	COG2189	Belongs to the N(4) N(6)-methyltransferase family
LFT47_15205	COG0613	PHP domain protein
LFT47_15210	COG0006	proline dipeptidase activity
LFT47_15220	COG1136	(ABC) transporter
LFT47_15220	COG0577	efflux transmembrane transporter activity
LFT47_15230	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LFT47_15240	COG2239	Acts as a magnesium transporter
LFT47_15265	COG1595	DNA-templated transcription, initiation
LFT47_15295	COG1126	abc transporter atp-binding protein
LFT47_15300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LFT47_15305	COG0765	amino acid transport
LFT47_15310	COG0765	amino acid transport
LFT47_15315	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LFT47_15320	COG2171	N-acyltransferase activity
LFT47_15335	COG3226	Transcriptional regulator
LFT47_15340	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LFT47_15385	COG1217	gtp-binding protein TYPA
LFT47_15395	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LFT47_15400	COG0601	transmembrane transport
LFT47_15405	COG4166	transmembrane transport
LFT47_15425	COG0601	transmembrane transport
LFT47_15430	COG4166	transmembrane transport
LFT47_15445	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LFT47_15470	COG0012	GTP binding
LFT47_15480	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LFT47_15490	COG1570	exodeoxyribonuclease VII activity
LFT47_15495	COG1722	exodeoxyribonuclease VII activity
LFT47_15500	COG2326	polyphosphate kinase activity
LFT47_15515	COG1174	glycine betaine transport
LFT47_15520	COG1174	glycine betaine transport
LFT47_15540	COG2971	BadF BadG BcrA BcrD
LFT47_15545	COG0583	DNA-binding transcription factor activity
LFT47_15550	COG2814	Major facilitator Superfamily
LFT47_15555	COG0626	cystathionine gamma-synthase activity
LFT47_15590	COG0598	Magnesium transport protein CorA
LFT47_15605	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LFT47_15610	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LFT47_15615	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LFT47_15640	COG4948	Mandelate Racemase Muconate Lactonizing
LFT47_15650	COG0246	Mannitol dehydrogenase
LFT47_15655	COG1904	glucuronate isomerase
LFT47_15660	COG1609	Transcriptional regulator
LFT47_15665	COG0673	inositol 2-dehydrogenase activity
LFT47_15700	COG3265	gluconokinase activity
LFT47_15750	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LFT47_15755	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LFT47_15775	COG0519	Catalyzes the synthesis of GMP from XMP
LFT47_15775	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LFT47_15795	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LFT47_15800	COG0516	GMP reductase activity
LFT47_15815	COG0459	protein refolding
LFT47_15820	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LFT47_15835	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LFT47_15840	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LFT47_15850	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
LFT47_15855	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LFT47_15870	COG0802	atpase or kinase
LFT47_15875	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LFT47_15890	COG0438	transferase activity, transferring glycosyl groups
LFT47_15895	COG2759	Belongs to the formate--tetrahydrofolate ligase family
LFT47_15910	COG0667	Aldo Keto reductase
LFT47_15940	COG0736	holo-[acyl-carrier-protein] synthase activity
LFT47_15950	COG1072	(Pantothenic acid kinase))
LFT47_15955	COG1876	peptidase activity
LFT47_15960	COG1970	mechanosensitive ion channel activity
LFT47_15965	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LFT47_15970	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LFT47_15970	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LFT47_15975	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LFT47_15980	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LFT47_16020	COG2894	cell division
LFT47_16040	COG0101	tRNA pseudouridine synthase activity
LFT47_16045	COG0203	ribosomal protein L17
LFT47_16050	COG0202	RNA polymerase activity
LFT47_16055	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LFT47_16060	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LFT47_16065	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LFT47_16070	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LFT47_16075	COG3191	aminopeptidase activity
LFT47_16085	COG0747	negative chemotaxis
LFT47_16100	COG0601	transmembrane transport
LFT47_16105	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LFT47_16115	COG2186	Transcriptional regulator
LFT47_16125	COG1175	transmembrane transport
LFT47_16140	COG0024	Methionine aminopeptidase
LFT47_16145	COG0563	adenylate kinase activity
LFT47_16155	COG0200	Binds to the 23S rRNA
LFT47_16160	COG1841	ribosomal large subunit assembly
LFT47_16165	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LFT47_16175	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LFT47_16180	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LFT47_16185	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LFT47_16190	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LFT47_16195	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LFT47_16200	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LFT47_16210	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LFT47_16215	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LFT47_16220	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LFT47_16225	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LFT47_16230	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LFT47_16235	COG0089	rRNA binding
LFT47_16240	COG0088	Forms part of the polypeptide exit tunnel
LFT47_16245	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LFT47_16250	COG0051	transcription antitermination factor activity, RNA binding
LFT47_16255	COG2723	6-phospho-beta-galactosidase activity
LFT47_16265	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LFT47_16270	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LFT47_16275	COG0049	tRNA binding
LFT47_16280	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LFT47_16285	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LFT47_16290	COG0085	RNA polymerase activity
LFT47_16295	COG0183	Belongs to the thiolase family
LFT47_16300	COG0442	prolyl-tRNA aminoacylation
LFT47_16305	COG0222	ribosome binding
LFT47_16310	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LFT47_16325	COG0081	regulation of translation
LFT47_16330	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LFT47_16350	COG0436	Aminotransferase
LFT47_16355	COG2197	response regulator
LFT47_16405	COG0354	folic acid binding
LFT47_16415	COG3485	protocatechuate 3,4-dioxygenase
LFT47_16425	COG0745	RESPONSE REGULATOR receiver
LFT47_16430	COG0456	acetyltransferase
LFT47_16435	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LFT47_16445	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LFT47_16460	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LFT47_16475	COG0812	UDP-N-acetylmuramate dehydrogenase activity
LFT47_16480	COG0738	Major facilitator superfamily
LFT47_16485	COG2030	dehydratase
LFT47_16490	COG2030	dehydratase
LFT47_16520	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LFT47_16530	COG4989	oxidoreductase activity
LFT47_16535	COG0366	Alpha amylase catalytic
LFT47_16540	COG1940	carbohydrate kinase activity
LFT47_16555	COG3942	CHAP domain
LFT47_16555	COG1388	LysM domain
LFT47_16645	COG0318	PFAM AMP-dependent synthetase and ligase
LFT47_16655	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LFT47_16680	COG1666	GTP binding
LFT47_16685	COG0672	)-iron permease
LFT47_16695	COG2837	iron assimilation
LFT47_16700	COG0501	Belongs to the peptidase M48B family
LFT47_16705	COG0531	amino acid
LFT47_16725	COG0531	amino acid
LFT47_16770	COG1012	belongs to the aldehyde dehydrogenase family
LFT47_16775	COG2508	Transcriptional regulator
LFT47_16775	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
LFT47_16790	COG2807	transmembrane transport
LFT47_16795	COG2186	Transcriptional regulator
LFT47_16800	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LFT47_16800	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LFT47_16810	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LFT47_16810	COG1648	precorrin-2 dehydrogenase activity
LFT47_16815	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LFT47_16825	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
LFT47_16845	COG0175	sulfate reduction
LFT47_16850	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LFT47_16860	COG2860	membrane
LFT47_16875	COG0142	geranyltranstransferase activity
LFT47_16880	COG0644	oxidoreductase
LFT47_16885	COG2226	methyltransferase
LFT47_16890	COG1169	isochorismate synthase
LFT47_16900	COG0765	amino acid transport
LFT47_16915	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
LFT47_16925	COG4948	Mandelate Racemase Muconate Lactonizing
LFT47_16935	COG1609	Transcriptional regulator
LFT47_16945	COG0395	ABC-type sugar transport system, permease component
LFT47_16950	COG1175	transmembrane transport
LFT47_17005	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LFT47_17015	COG0640	Transcriptional regulator
LFT47_17020	COG0702	epimerase
LFT47_17030	COG3979	chitinase
LFT47_17040	COG0640	Transcriptional regulator
LFT47_17055	COG2814	Major facilitator Superfamily
LFT47_17085	COG3287	FIST C domain
LFT47_17085	COG2199	diguanylate cyclase activity
LFT47_17085	COG2200	EAL domain
LFT47_17090	COG1309	transcriptional regulator
LFT47_17125	COG0745	RESPONSE REGULATOR receiver
LFT47_17125	COG2205	protein histidine kinase activity
LFT47_17125	COG4191	Histidine kinase
LFT47_17150	COG0508	dehydrogenase complex catalyzes the overall conversion of
LFT47_17155	COG0022	dehydrogenase e1 component
LFT47_17175	COG0489	protein tyrosine kinase activity
LFT47_17210	COG0438	transferase activity, transferring glycosyl groups
LFT47_17225	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LFT47_17240	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LFT47_17245	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LFT47_17265	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LFT47_17270	COG1316	TRANSCRIPTIONal
LFT47_17280	COG0640	Transcriptional regulator
LFT47_17305	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LFT47_17310	COG2151	metal-sulfur cluster biosynthetic enzyme
LFT47_17315	COG3396	Phenylacetate-CoA oxygenase
LFT47_17320	COG3460	Phenylacetate-CoA oxygenase
LFT47_17325	COG3396	Phenylacetate-CoA oxygenase
LFT47_17340	COG0745	RESPONSE REGULATOR receiver
LFT47_17365	COG2894	cell division
LFT47_17395	COG0574	Belongs to the PEP-utilizing enzyme family
LFT47_17395	COG3848	Pyruvate phosphate dikinase
LFT47_17410	COG1316	TRANSCRIPTIONal
LFT47_17435	COG5002	protein histidine kinase activity
LFT47_17445	COG0745	RESPONSE REGULATOR receiver
LFT47_17465	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LFT47_17475	COG0747	negative chemotaxis
LFT47_17490	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LFT47_17500	COG1116	anion transmembrane transporter activity
LFT47_17515	COG2050	protein possibly involved in aromatic compounds catabolism
LFT47_17540	COG1012	belongs to the aldehyde dehydrogenase family
LFT47_17540	COG2030	dehydratase
LFT47_17550	COG1609	Transcriptional regulator
LFT47_17555	COG2182	Extracellular solute-binding protein
LFT47_17565	COG0395	ABC-type sugar transport system, permease component
LFT47_17575	COG0673	inositol 2-dehydrogenase activity
LFT47_17580	COG2801	Transposase and inactivated derivatives
LFT47_17580	COG3415	Transposase
LFT47_17585	COG1280	lysine exporter protein (LysE YggA)
LFT47_17590	COG2755	lipolytic protein G-D-S-L family
LFT47_17600	COG2801	Transposase and inactivated derivatives
LFT47_17600	COG3415	Transposase
LFT47_17610	COG1250	3-hydroxyacyl-CoA dehydrogenase
LFT47_17615	COG1024	Enoyl-CoA hydratase
LFT47_17620	COG0183	Belongs to the thiolase family
LFT47_17655	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LFT47_17680	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LFT47_17690	COG0785	Cytochrome C biogenesis protein
LFT47_17700	COG0406	alpha-ribazole phosphatase activity
LFT47_17720	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
LFT47_17745	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LFT47_17750	COG1609	Transcriptional regulator
LFT47_17765	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LFT47_17780	COG0640	Transcriptional regulator
LFT47_17785	COG0123	including yeast histone deacetylase and acetoin utilization protein
LFT47_17790	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LFT47_17795	COG0569	domain protein
LFT47_17800	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LFT47_17805	COG1082	Xylose isomerase domain protein TIM barrel
LFT47_17810	COG0248	Ppx GppA phosphatase
LFT47_17825	COG1754	DNA topoisomerase type I activity
LFT47_17825	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LFT47_17835	COG2890	protein-(glutamine-N5) methyltransferase activity
LFT47_17850	COG1054	Belongs to the UPF0176 family
LFT47_17860	COG1111	helicase
LFT47_17860	COG1205	dead DEAH box helicase
LFT47_17930	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LFT47_17940	COG1175	transmembrane transport
LFT47_17945	COG0395	ABC-type sugar transport system, permease component
LFT47_17955	COG1349	DNA-binding transcription factor activity
LFT47_17960	COG1609	Transcriptional regulator
LFT47_17970	COG1175	transmembrane transport
LFT47_17975	COG0395	ABC-type sugar transport system, permease component
LFT47_17990	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
LFT47_18020	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LFT47_18025	COG1408	metallophosphoesterase
LFT47_18030	COG1132	(ABC) transporter
LFT47_18035	COG1132	(ABC) transporter
LFT47_18055	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
LFT47_18060	COG0151	Belongs to the GarS family
LFT47_18080	COG1301	dicarboxylic acid transport
LFT47_18085	COG2066	Belongs to the glutaminase family
LFT47_18090	COG1028	Short-chain dehydrogenase reductase Sdr
LFT47_18100	COG1953	Uracil, thiamine, allantoin
LFT47_18105	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
LFT47_18120	COG3415	Transposase
LFT47_18120	COG2801	Transposase and inactivated derivatives
LFT47_18125	COG1529	Aldehyde oxidase and xanthine dehydrogenase
LFT47_18125	COG2080	2 iron, 2 sulfur cluster binding
LFT47_18135	COG3608	succinylglutamate desuccinylase aspartoacylase
LFT47_18135	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
LFT47_18140	COG2252	PERMEase
LFT47_18145	COG0590	tRNA wobble adenosine to inosine editing
LFT47_18170	COG2233	PERMEase
LFT47_18180	COG1953	Uracil, thiamine, allantoin
LFT47_18185	COG1414	Transcriptional regulator
LFT47_18195	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
LFT47_18205	COG3257	ureidoglycine aminohydrolase activity
LFT47_18210	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LFT47_18215	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LFT47_18230	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LFT47_18235	COG3387	PFAM Glycoside hydrolase 15-related
LFT47_18240	COG0563	adenylate kinase activity
LFT47_18245	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LFT47_18255	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LFT47_18275	COG2084	Dehydrogenase
LFT47_18280	COG1012	belongs to the aldehyde dehydrogenase family
LFT47_18285	COG4948	Mandelate Racemase Muconate Lactonizing
LFT47_18295	COG1732	Glycine betaine
LFT47_18300	COG1174	glycine betaine transport
LFT47_18305	COG0517	IMP dehydrogenase activity
LFT47_18305	COG1125	glycine betaine transport
LFT47_18310	COG1174	glycine betaine transport
LFT47_18385	COG1028	Short-chain dehydrogenase reductase Sdr
LFT47_18410	COG2084	Dehydrogenase
LFT47_18415	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
LFT47_18415	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
LFT47_18420	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LFT47_18430	COG1609	Transcriptional regulator
LFT47_18440	COG1028	Short-chain dehydrogenase reductase Sdr
LFT47_18475	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LFT47_18500	COG3958	Transketolase
LFT47_18505	COG3959	Transketolase, thiamine diphosphate binding domain
LFT47_18510	COG0477	Major facilitator Superfamily
LFT47_18515	COG1082	Xylose isomerase domain protein TIM barrel
LFT47_18520	COG1028	Short-chain dehydrogenase reductase Sdr
LFT47_18525	COG2376	Dihydroxyacetone kinase
LFT47_18530	COG0698	ribose 5-phosphate isomerase
LFT47_18540	COG1609	Transcriptional regulator
LFT47_18550	COG1175	transmembrane transport
LFT47_18555	COG0395	ABC-type sugar transport system, permease component
LFT47_18560	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
LFT47_18575	COG2971	BadF BadG BcrA BcrD
LFT47_18615	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LFT47_18625	COG1733	regulation of RNA biosynthetic process
LFT47_18630	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
LFT47_18655	COG2267	carboxylic ester hydrolase activity
LFT47_18670	COG3842	ATPase activity
LFT47_18685	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
LFT47_18690	COG1175	transmembrane transport
LFT47_18695	COG0395	ABC-type sugar transport system, permease component
LFT47_18700	COG1228	amidohydrolase
LFT47_18705	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LFT47_18735	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
LFT47_18740	COG2986	histidine ammonia-lyase
LFT47_18815	COG1136	(ABC) transporter
LFT47_18825	COG3622	Belongs to the hyi family
LFT47_18830	COG2084	Dehydrogenase
LFT47_18835	COG3960	tartronate-semialdehyde synthase activity
LFT47_18840	COG1929	Belongs to the glycerate kinase type-1 family
LFT47_18845	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LFT47_18875	COG0765	amino acid transport
LFT47_18900	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LFT47_18905	COG1126	abc transporter atp-binding protein
LFT47_18910	COG0765	amino acid transport
LFT47_18925	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
LFT47_18945	COG1012	belongs to the aldehyde dehydrogenase family
LFT47_18950	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
LFT47_18960	COG2186	Transcriptional regulator
LFT47_18980	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
LFT47_18995	COG0640	Transcriptional regulator
LFT47_19010	COG0542	response to heat
LFT47_19055	COG0028	Belongs to the TPP enzyme family
LFT47_19060	COG3304	Inner membrane component domain
LFT47_19065	COG1793	dna ligase
LFT47_19085	COG0135	phosphoribosylanthranilate isomerase activity
LFT47_19105	COG0667	Aldo Keto reductase
LFT47_19145	COG1473	amidohydrolase
LFT47_19150	COG0477	Major facilitator Superfamily
LFT47_19155	COG2807	transmembrane transport
LFT47_19160	COG0220	tRNA (guanine-N7-)-methyltransferase activity
LFT47_19165	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LFT47_19195	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LFT47_19220	COG1172	Belongs to the binding-protein-dependent transport system permease family
LFT47_19245	COG1113	amino acid transport
LFT47_19250	COG0251	oxidation-reduction process
LFT47_19285	COG0789	Transcriptional regulator
LFT47_19290	COG0484	heat shock protein binding
LFT47_19295	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LFT47_19300	COG0443	Heat shock 70 kDa protein
LFT47_19305	COG3739	integral membrane protein
LFT47_19325	COG2409	Drug exporters of the RND superfamily
LFT47_19345	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
LFT47_19355	COG2226	methyltransferase
LFT47_19360	COG3795	YCII-related domain
LFT47_19365	COG4941	Belongs to the sigma-70 factor family
LFT47_19385	COG1280	lysine exporter protein (LysE YggA)
LFT47_19395	COG1609	Transcriptional regulator
LFT47_19400	COG1957	nucleoside hydrolase
LFT47_19405	COG0477	Major facilitator Superfamily
LFT47_19410	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LFT47_19415	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LFT47_19425	COG1953	Uracil, thiamine, allantoin
LFT47_19450	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LFT47_19510	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
LFT47_19520	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LFT47_19530	COG1122	ATPase activity
LFT47_19535	COG4721	ABC-type cobalt transport system, permease component
LFT47_19550	COG1320	monovalent cation:proton antiporter activity
LFT47_19555	COG2212	antiporter activity
LFT47_19565	COG0651	ATP synthesis coupled electron transport
LFT47_19570	COG1006	Multisubunit Na H antiporter MnhC subunit
LFT47_19575	COG2111	Na H antiporter
LFT47_19575	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LFT47_19590	COG1472	Belongs to the glycosyl hydrolase 3 family
LFT47_19595	COG0363	glucosamine-6-phosphate deaminase activity
LFT47_19600	COG0490	domain, Protein
LFT47_19600	COG2985	domain, Protein
LFT47_19605	COG0475	glutathione-regulated potassium exporter activity
LFT47_19615	COG0717	Belongs to the dCTP deaminase family
LFT47_19645	COG0583	DNA-binding transcription factor activity
LFT47_19650	COG1309	transcriptional regulator
LFT47_19660	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
LFT47_19670	COG3387	PFAM Glycoside hydrolase 15-related
LFT47_19675	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LFT47_19685	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LFT47_19690	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LFT47_19710	COG3559	Exporter of polyketide antibiotics
LFT47_19720	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LFT47_19725	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LFT47_19730	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LFT47_19740	COG1126	abc transporter atp-binding protein
LFT47_19745	COG0765	amino acid transport
LFT47_19760	COG2318	DinB family
LFT47_19770	COG0433	COG0433 Predicted ATPase
LFT47_19785	COG3336	cytochrome c oxidase
LFT47_19790	COG0776	regulation of translation
LFT47_19810	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LFT47_19815	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LFT47_19820	COG0227	Belongs to the bacterial ribosomal protein bL28 family
LFT47_19825	COG1017	nitric oxide dioxygenase activity
LFT47_19825	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LFT47_19875	COG1120	ATPase activity
LFT47_19880	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LFT47_19885	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LFT47_19925	COG3012	SEC-C Motif Domain Protein
LFT47_19940	COG0667	Aldo Keto reductase
LFT47_19955	COG0438	transferase activity, transferring glycosyl groups
LFT47_19970	COG3177	Filamentation induced by cAMP protein fic
LFT47_19975	COG2186	Transcriptional regulator
LFT47_19985	COG1027	Aspartate ammonia-lyase
LFT47_19995	COG2186	Transcriptional regulator
LFT47_20010	COG3254	rhamnose metabolic process
LFT47_20020	COG0395	ABC-type sugar transport system, permease component
LFT47_20025	COG1175	transmembrane transport
LFT47_20035	COG4948	Mandelate Racemase Muconate Lactonizing
LFT47_20045	COG1028	Short-chain dehydrogenase reductase Sdr
LFT47_20050	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LFT47_20090	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LFT47_20100	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LFT47_20115	COG1028	Short-chain dehydrogenase reductase Sdr
LFT47_20135	COG0477	Major facilitator Superfamily
LFT47_20155	COG1522	sequence-specific DNA binding
LFT47_20160	COG1280	lysine exporter protein (LysE YggA)
LFT47_20180	COG2197	response regulator
LFT47_20185	COG4585	Histidine kinase
LFT47_20190	COG0281	malic enzyme
LFT47_20195	COG1309	transcriptional regulator
LFT47_20205	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LFT47_20210	COG0477	Major facilitator Superfamily
LFT47_20215	COG0477	Major facilitator Superfamily
LFT47_20220	COG2814	Major facilitator Superfamily
LFT47_20235	COG1113	amino acid transport
LFT47_20245	COG1846	Transcriptional regulator
LFT47_20250	COG0246	Mannitol dehydrogenase
LFT47_20255	COG2213	PTS system mannitol-specific
LFT47_20255	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LFT47_20265	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LFT47_20270	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LFT47_20275	COG1960	acyl-CoA dehydrogenase activity
LFT47_20280	COG1309	transcriptional regulator
LFT47_20295	COG2072	flavoprotein involved in K transport
LFT47_20310	COG0686	Belongs to the AlaDH PNT family
LFT47_20330	COG0673	inositol 2-dehydrogenase activity
LFT47_20335	COG1309	transcriptional regulator
LFT47_20340	COG0431	NADPH-dependent FMN reductase
LFT47_20360	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LFT47_20380	COG0508	dehydrogenase complex catalyzes the overall conversion of
LFT47_20385	COG0022	dehydrogenase e1 component
LFT47_20395	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LFT47_20400	COG1950	PFAM Membrane protein of
LFT47_20415	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LFT47_20435	COG1607	acyl-coa hydrolase
LFT47_20440	COG4221	oxidoreductase activity
LFT47_20445	COG0477	Major facilitator Superfamily
LFT47_20450	COG1984	allophanate hydrolase subunit 2
LFT47_20455	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
LFT47_20460	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
LFT47_20465	COG0583	DNA-binding transcription factor activity
LFT47_20475	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LFT47_20480	COG0436	Aminotransferase
LFT47_20500	COG3971	2-oxopent-4-enoate hydratase activity
LFT47_20515	COG1802	Transcriptional regulator
LFT47_20530	COG0596	Alpha beta hydrolase
LFT47_20575	COG4221	oxidoreductase activity
LFT47_20590	COG1132	(ABC) transporter
LFT47_20605	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
LFT47_20610	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
LFT47_20615	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
LFT47_20655	COG1850	ribulose-bisphosphate carboxylase activity
LFT47_20660	COG2186	Transcriptional regulator
LFT47_20670	COG1653	transport
LFT47_20675	COG1175	transmembrane transport
LFT47_20685	COG0673	inositol 2-dehydrogenase activity
LFT47_20705	COG1940	carbohydrate kinase activity
LFT47_20715	COG1070	Carbohydrate kinase
LFT47_20720	COG2115	Belongs to the xylose isomerase family
LFT47_20725	COG0277	FAD linked oxidase domain protein
LFT47_20730	COG1940	carbohydrate kinase activity
LFT47_20735	COG2017	converts alpha-aldose to the beta-anomer
LFT47_20770	COG1970	mechanosensitive ion channel activity
LFT47_20785	COG0506	proline dehydrogenase activity
LFT47_20790	COG2271	Major facilitator Superfamily
LFT47_20815	COG1278	Cold shock
LFT47_20855	COG0251	oxidation-reduction process
LFT47_20865	COG0765	amino acid transport
LFT47_20885	COG2161	toxin-antitoxin pair type II binding
LFT47_20920	COG1414	Transcriptional regulator
LFT47_20925	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LFT47_20935	COG0183	Belongs to the thiolase family
LFT47_20940	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LFT47_20950	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LFT47_20960	COG3485	protocatechuate 3,4-dioxygenase
LFT47_20965	COG1082	Xylose isomerase domain protein TIM barrel
LFT47_20965	COG3185	4-Hydroxyphenylpyruvate dioxygenase
LFT47_20970	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LFT47_20975	COG1414	Transcriptional regulator
LFT47_20980	COG0477	Major facilitator Superfamily
LFT47_20990	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
LFT47_21005	COG2610	gluconate transmembrane transporter activity
LFT47_21015	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
LFT47_21030	COG1414	Transcriptional regulator
LFT47_21040	COG5001	Diguanylate cyclase
LFT47_21040	COG4251	negative regulation of phosphorylation
LFT47_21040	COG2203	Gaf domain
LFT47_21040	COG3706	GGDEF domain
LFT47_21050	COG1414	Transcriptional regulator
LFT47_21055	COG3525	Glycosyl hydrolase, family 20, catalytic domain
LFT47_21060	COG0395	ABC-type sugar transport system, permease component
LFT47_21070	COG1653	transport
LFT47_21075	COG1937	Protein conserved in bacteria
LFT47_21115	COG0534	Mate efflux family protein
LFT47_21130	COG1607	acyl-coa hydrolase
LFT47_21140	COG0305	Participates in initiation and elongation during chromosome replication
LFT47_21165	COG0359	binds to the 23S rRNA
LFT47_21170	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LFT47_21180	COG0360	Binds together with S18 to 16S ribosomal RNA
LFT47_21185	COG1742	UPF0060 membrane protein
LFT47_21195	COG1362	aminopeptidase activity
LFT47_21205	COG2197	response regulator
LFT47_21210	COG4585	Histidine kinase
LFT47_21220	COG1131	(ABC) transporter
LFT47_21235	COG1136	(ABC) transporter
LFT47_21240	COG0577	efflux transmembrane transporter activity
LFT47_21240	COG1136	(ABC) transporter
LFT47_21250	COG0738	Major facilitator superfamily
LFT47_21260	COG0488	(ABC) transporter
LFT47_21265	COG1309	transcriptional regulator
LFT47_21275	COG0768	penicillin binding
LFT47_21280	COG2197	response regulator
LFT47_21285	COG4585	Histidine kinase
LFT47_21295	COG1136	(ABC) transporter
LFT47_21300	COG2801	Transposase and inactivated derivatives
LFT47_21300	COG3415	Transposase
LFT47_21305	COG1733	regulation of RNA biosynthetic process
LFT47_21310	COG2910	NAD(P)H-binding
LFT47_21330	COG0406	alpha-ribazole phosphatase activity
LFT47_21335	COG0617	tRNA 3'-terminal CCA addition
LFT47_21355	COG0492	ferredoxin-NADP+ reductase activity
LFT47_21360	COG3118	belongs to the thioredoxin family
LFT47_21370	COG1192	Involved in chromosome partitioning
LFT47_21375	COG0357	Ribosomal RNA small subunit methyltransferase G
LFT47_21385	COG0706	membrane insertase activity
LFT47_21390	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
LFT47_21395	COG0594	ribonuclease P activity
LFT47_21400	COG0230	Belongs to the bacterial ribosomal protein bL34 family