locus-tag	class	description
OUO20_00010	COG0395	ABC-type sugar transport system, permease component
OUO20_00020	COG0673	inositol 2-dehydrogenase activity
OUO20_00035	COG0246	Mannitol dehydrogenase
OUO20_00045	COG4948	Mandelate Racemase Muconate Lactonizing
OUO20_00065	COG1063	alcohol dehydrogenase
OUO20_00105	COG0671	phosphoesterase, PA-phosphatase related
OUO20_00110	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
OUO20_00125	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
OUO20_00130	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
OUO20_00140	COG2205	protein histidine kinase activity
OUO20_00145	COG0745	RESPONSE REGULATOR receiver
OUO20_00160	COG2062	phosphohistidine phosphatase, SixA
OUO20_00180	COG1309	transcriptional regulator
OUO20_00205	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
OUO20_00210	COG1017	nitric oxide dioxygenase activity
OUO20_00210	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OUO20_00225	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OUO20_00230	COG0514	ATP-dependent DNA helicase (RecQ)
OUO20_00270	COG1136	(ABC) transporter
OUO20_00270	COG0577	efflux transmembrane transporter activity
OUO20_00285	COG1966	Carbon starvation protein
OUO20_00305	COG0656	L-ascorbic acid biosynthetic process
OUO20_00325	COG1252	NADH dehydrogenase
OUO20_00355	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
OUO20_00375	COG0588	phosphoglycerate mutase activity
OUO20_00385	COG5002	protein histidine kinase activity
OUO20_00405	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
OUO20_00410	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
OUO20_00415	COG0215	cysteine-tRNA ligase activity
OUO20_00440	COG0028	Belongs to the TPP enzyme family
OUO20_00490	COG0366	Alpha amylase catalytic
OUO20_00495	COG0277	FAD linked oxidase domain protein
OUO20_00545	COG4214	carbohydrate transport
OUO20_00550	COG1129	ABC transporter
OUO20_00555	COG4213	ABC transporter substrate-binding protein
OUO20_00570	COG2160	L-arabinose isomerase activity
OUO20_00575	COG1609	Transcriptional regulator
OUO20_00600	COG0783	Belongs to the Dps family
OUO20_00615	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
OUO20_00615	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
OUO20_00655	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
OUO20_00680	COG0459	protein refolding
OUO20_00685	COG1653	transport
OUO20_00690	COG0328	RNA-DNA hybrid ribonuclease activity
OUO20_00700	COG2205	protein histidine kinase activity
OUO20_00705	COG0745	RESPONSE REGULATOR receiver
OUO20_00725	COG1061	Type III restriction enzyme res subunit
OUO20_00740	COG1278	Cold shock
OUO20_00750	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
OUO20_00760	COG0739	heme binding
OUO20_00765	COG3103	Sh3 type 3 domain protein
OUO20_00765	COG1388	LysM domain
OUO20_00765	COG0791	NLP P60 protein
OUO20_00795	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
OUO20_00820	COG1132	(ABC) transporter
OUO20_00850	COG0483	inositol monophosphate 1-phosphatase activity
OUO20_00865	COG0045	succinate-CoA ligase (ADP-forming) activity
OUO20_00890	COG1028	Short-chain dehydrogenase reductase Sdr
OUO20_00900	COG1082	Xylose isomerase domain protein TIM barrel
OUO20_00915	COG1250	3-hydroxyacyl-CoA dehydrogenase
OUO20_00920	COG1028	Short-chain dehydrogenase reductase Sdr
OUO20_00925	COG2271	Major facilitator Superfamily
OUO20_00940	COG0640	Transcriptional regulator
OUO20_00955	COG3962	Belongs to the TPP enzyme family
OUO20_00970	COG0673	inositol 2-dehydrogenase activity
OUO20_00975	COG2814	Major facilitator Superfamily
OUO20_00980	COG1846	Transcriptional regulator
OUO20_00985	COG2814	Major facilitator Superfamily
OUO20_00990	COG3718	enzyme involved in inositol metabolism
OUO20_00995	COG2188	Transcriptional regulator
OUO20_01020	COG1396	sequence-specific DNA binding
OUO20_01030	COG0028	Belongs to the TPP enzyme family
OUO20_01040	COG0477	Major facilitator Superfamily
OUO20_01065	COG1401	restriction endodeoxyribonuclease activity
OUO20_01075	COG5002	protein histidine kinase activity
OUO20_01080	COG0745	RESPONSE REGULATOR receiver
OUO20_01090	COG4124	Belongs to the glycosyl hydrolase 26 family
OUO20_01090	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
OUO20_01120	COG1902	pentaerythritol trinitrate reductase activity
OUO20_01155	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OUO20_01170	COG3583	domain protein
OUO20_01180	COG3103	Sh3 type 3 domain protein
OUO20_01180	COG0366	Alpha amylase catalytic
OUO20_01185	COG1254	Belongs to the acylphosphatase family
OUO20_01200	COG0477	Major facilitator Superfamily
OUO20_01205	COG1063	alcohol dehydrogenase
OUO20_01220	COG0246	Mannitol dehydrogenase
OUO20_01225	COG0800	Aldolase
OUO20_01235	COG0514	ATP-dependent DNA helicase (RecQ)
OUO20_01250	COG0667	Aldo Keto reductase
OUO20_01255	COG1063	alcohol dehydrogenase
OUO20_01270	COG0477	Major facilitator Superfamily
OUO20_01280	COG1253	flavin adenine dinucleotide binding
OUO20_01290	COG0179	Fumarylacetoacetate (FAA) hydrolase
OUO20_01310	COG4948	Mandelate Racemase Muconate Lactonizing
OUO20_01320	COG2186	Transcriptional regulator
OUO20_01330	COG1175	transmembrane transport
OUO20_01335	COG0395	ABC-type sugar transport system, permease component
OUO20_01345	COG0640	Transcriptional regulator
OUO20_01395	COG0395	ABC-type sugar transport system, permease component
OUO20_01400	COG1175	transmembrane transport
OUO20_01410	COG3684	Belongs to the aldolase LacD family
OUO20_01420	COG0673	inositol 2-dehydrogenase activity
OUO20_01465	COG0477	Major facilitator Superfamily
OUO20_01490	COG4209	transmembrane transport
OUO20_01495	COG0395	ABC-type sugar transport system, permease component
OUO20_01520	COG1472	Belongs to the glycosyl hydrolase 3 family
OUO20_01525	COG0673	inositol 2-dehydrogenase activity
OUO20_01540	COG1609	Transcriptional regulator
OUO20_01580	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
OUO20_01590	COG4770	biotin carboxylase activity
OUO20_01670	COG0395	ABC-type sugar transport system, permease component
OUO20_01745	COG3619	membrane
OUO20_01775	COG3848	Pyruvate phosphate dikinase
OUO20_01775	COG0574	Belongs to the PEP-utilizing enzyme family
OUO20_01780	COG0574	Belongs to the PEP-utilizing enzyme family
OUO20_01780	COG3848	Pyruvate phosphate dikinase
OUO20_01825	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
OUO20_01830	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
OUO20_01860	COG0028	Belongs to the TPP enzyme family
OUO20_01875	COG1113	amino acid transport
OUO20_01910	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OUO20_01915	COG0531	amino acid
OUO20_01920	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OUO20_01965	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
OUO20_01975	COG1715	Restriction endonuclease
OUO20_02030	COG2350	Protein conserved in bacteria
OUO20_02045	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
OUO20_02085	COG1349	DNA-binding transcription factor activity
OUO20_02090	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
OUO20_02095	COG3395	kinase activity
OUO20_02170	COG3540	Alkaline phosphatase
OUO20_02175	COG1028	Short-chain dehydrogenase reductase Sdr
OUO20_02200	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
OUO20_02240	COG2072	flavoprotein involved in K transport
OUO20_02270	COG1278	Cold shock
OUO20_02285	COG3265	gluconokinase activity
OUO20_02290	COG2610	gluconate transmembrane transporter activity
OUO20_02305	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OUO20_02320	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OUO20_02325	COG0546	phosphoglycolate phosphatase activity
OUO20_02335	COG1012	belongs to the aldehyde dehydrogenase family
OUO20_02350	COG0833	amino acid
OUO20_02360	COG1414	Transcriptional regulator
OUO20_02375	COG2040	homocysteine
OUO20_02385	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
OUO20_02400	COG3437	response regulator, receiver
OUO20_02400	COG3850	Histidine kinase
OUO20_02400	COG4999	Histidine kinase
OUO20_02400	COG2205	protein histidine kinase activity
OUO20_02405	COG5001	Diguanylate cyclase
OUO20_02405	COG3300	MHYT domain
OUO20_02410	COG2261	transglycosylase associated protein
OUO20_02415	COG0561	phosphatase activity
OUO20_02420	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
OUO20_02425	COG0438	transferase activity, transferring glycosyl groups
OUO20_02425	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
OUO20_02430	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
OUO20_02450	COG0477	Major facilitator Superfamily
OUO20_02455	COG0138	bifunctional purine biosynthesis protein purh
OUO20_02470	COG2838	Isocitrate dehydrogenase
OUO20_02480	COG0515	serine threonine protein kinase
OUO20_02500	COG1136	(ABC) transporter
OUO20_02510	COG0464	growth
OUO20_02515	COG4213	ABC transporter substrate-binding protein
OUO20_02535	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OUO20_02545	COG0531	amino acid
OUO20_02565	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
OUO20_02600	COG0180	Tryptophanyl-tRNA synthetase
OUO20_02630	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
OUO20_02660	COG1846	Transcriptional regulator
OUO20_02665	COG1764	response to oxidative stress
OUO20_02670	COG2130	NADP-dependent
OUO20_02675	COG1744	ABC transporter substrate-binding protein PnrA-like
OUO20_02680	COG3845	ABC transporter
OUO20_02705	COG0586	Pfam SNARE associated Golgi protein
OUO20_02710	COG0586	Pfam SNARE associated Golgi protein
OUO20_02715	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
OUO20_02720	COG3956	TIGRFAM MazG family protein
OUO20_02725	COG0148	phosphopyruvate hydratase activity
OUO20_02745	COG1404	Belongs to the peptidase S8 family
OUO20_02750	COG1252	NADH dehydrogenase
OUO20_02790	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
OUO20_02800	COG2017	converts alpha-aldose to the beta-anomer
OUO20_02810	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
OUO20_02820	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
OUO20_02830	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
OUO20_02845	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
OUO20_02850	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
OUO20_02885	COG0114	fumarate hydratase activity
OUO20_02890	COG0288	reversible hydration of carbon dioxide
OUO20_02910	COG1482	cell wall glycoprotein biosynthetic process
OUO20_02970	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
OUO20_03030	COG0714	Associated with various cellular activities
OUO20_03035	COG0084	hydrolase, TatD family'
OUO20_03040	COG3583	domain protein
OUO20_03050	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
OUO20_03055	COG0488	(ABC) transporter
OUO20_03070	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
OUO20_03080	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
OUO20_03085	COG0193	aminoacyl-tRNA hydrolase activity
OUO20_03110	COG0822	iron-sulfur transferase activity
OUO20_03145	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
OUO20_03160	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
OUO20_03160	COG1648	precorrin-2 dehydrogenase activity
OUO20_03165	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OUO20_03175	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OUO20_03220	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OUO20_03225	COG0243	molybdopterin cofactor binding
OUO20_03230	COG2223	nitrite transmembrane transporter activity
OUO20_03235	COG0477	Major facilitator Superfamily
OUO20_03255	COG0424	maF-like protein
OUO20_03260	COG2409	Drug exporters of the RND superfamily
OUO20_03275	COG1823	symporter activity
OUO20_03290	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OUO20_03300	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
OUO20_03300	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
OUO20_03320	COG0714	Associated with various cellular activities
OUO20_03345	COG0631	protein serine/threonine phosphatase activity
OUO20_03370	COG1674	ftsk spoiiie
OUO20_03380	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
OUO20_03385	COG0483	inositol monophosphate 1-phosphatase activity
OUO20_03395	COG0251	oxidation-reduction process
OUO20_03400	COG4565	transcriptional regulatory protein
OUO20_03410	COG2851	Citrate transporter
OUO20_03415	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OUO20_03420	COG0154	amidase activity
OUO20_03435	COG0583	DNA-binding transcription factor activity
OUO20_03440	COG1063	alcohol dehydrogenase
OUO20_03455	COG1228	amidohydrolase
OUO20_03485	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OUO20_03525	COG0400	carboxylic ester hydrolase activity
OUO20_03540	COG0423	glycine-tRNA ligase activity
OUO20_03630	COG2814	Major facilitator Superfamily
OUO20_03670	COG0052	Belongs to the universal ribosomal protein uS2 family
OUO20_03675	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
OUO20_03680	COG0528	UMP kinase activity
OUO20_03685	COG0233	cytoplasmic translational termination
OUO20_03705	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OUO20_03715	COG3279	Response regulator of the LytR AlgR family
OUO20_03720	COG3275	phosphorelay sensor kinase activity
OUO20_03735	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OUO20_03755	COG1522	sequence-specific DNA binding
OUO20_03765	COG0022	dehydrogenase e1 component
OUO20_03770	COG0508	dehydrogenase complex catalyzes the overall conversion of
OUO20_03790	COG1960	acyl-CoA dehydrogenase activity
OUO20_03820	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
OUO20_03850	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
OUO20_03870	COG1309	transcriptional regulator
OUO20_03885	COG0442	prolyl-tRNA aminoacylation
OUO20_03900	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
OUO20_03915	COG0779	Required for maturation of 30S ribosomal subunits
OUO20_03920	COG0195	Participates in both transcription termination and antitermination
OUO20_03930	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
OUO20_03935	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
OUO20_03945	COG0590	tRNA wobble adenosine to inosine editing
OUO20_03955	COG0436	Aminotransferase
OUO20_03960	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
OUO20_03980	COG3483	tryptophan 2,3-dioxygenase activity
OUO20_03990	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
OUO20_03995	COG1185	polyribonucleotide nucleotidyltransferase activity
OUO20_04000	COG0612	Peptidase, M16
OUO20_04050	COG0521	Mo-molybdopterin cofactor biosynthetic process
OUO20_04060	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
OUO20_04085	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
OUO20_04100	COG1058	Belongs to the CinA family
OUO20_04100	COG1546	Belongs to the CinA family
OUO20_04105	COG1396	sequence-specific DNA binding
OUO20_04120	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
OUO20_04125	COG2137	regulation of response to DNA damage stimulus
OUO20_04130	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OUO20_04135	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
OUO20_04140	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
OUO20_04145	COG2813	Specifically methylates the guanine in position
OUO20_04150	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
OUO20_04170	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
OUO20_04175	COG0131	Imidazoleglycerol-phosphate dehydratase
OUO20_04180	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
OUO20_04210	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
OUO20_04215	COG0291	Belongs to the bacterial ribosomal protein bL35 family
OUO20_04220	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
OUO20_04245	COG0494	nUDIX hydrolase
OUO20_04265	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
OUO20_04270	COG0072	phenylalanine-tRNA ligase activity
OUO20_04270	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OUO20_04280	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
OUO20_04290	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
OUO20_04295	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OUO20_04300	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
OUO20_04305	COG1438	arginine binding
OUO20_04315	COG0165	Argininosuccinate lyase
OUO20_04330	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OUO20_04330	COG2169	Transcriptional regulator
OUO20_04340	COG2094	Belongs to the DNA glycosylase MPG family
OUO20_04345	COG3973	AAA domain
OUO20_04375	COG0647	UMP catabolic process
OUO20_04390	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
OUO20_04395	COG0497	DNA recombination
OUO20_04400	COG0504	CTP synthase activity
OUO20_04405	COG0494	nUDIX hydrolase
OUO20_04430	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
OUO20_04435	COG2079	MmgE PrpD family protein
OUO20_04455	COG3290	protein histidine kinase activity
OUO20_04460	COG1301	dicarboxylic acid transport
OUO20_04470	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
OUO20_04475	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
OUO20_04490	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
OUO20_04500	COG1160	GTP binding
OUO20_04520	COG0509	glycine decarboxylation via glycine cleavage system
OUO20_04525	COG1716	ATPase activity
OUO20_04550	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
OUO20_04560	COG1940	carbohydrate kinase activity
OUO20_04585	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
OUO20_04590	COG0515	serine threonine protein kinase
OUO20_04590	COG2815	serine threonine protein kinase
OUO20_04595	COG1388	LysM domain
OUO20_04595	COG3942	CHAP domain
OUO20_04605	COG0142	geranyltranstransferase activity
OUO20_04615	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OUO20_04625	COG2001	Belongs to the MraZ family
OUO20_04630	COG0275	rRNA processing
OUO20_04640	COG0768	penicillin binding
OUO20_04645	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
OUO20_04660	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
OUO20_04665	COG0772	Belongs to the SEDS family
OUO20_04670	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
OUO20_04675	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
OUO20_04680	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
OUO20_04685	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
OUO20_04695	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
OUO20_04700	COG1799	cell septum assembly
OUO20_04710	COG3599	regulation of cell shape
OUO20_04715	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
OUO20_04725	COG0587	DNA-directed DNA polymerase activity
OUO20_04740	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
OUO20_04770	COG0174	glutamine synthetase
OUO20_04775	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
OUO20_04810	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
OUO20_04815	COG0321	lipoyl(octanoyl) transferase activity
OUO20_04830	COG1090	epimerase
OUO20_04835	COG0793	Belongs to the peptidase S41A family
OUO20_04835	COG4946	Tricorn protease homolog
OUO20_04840	COG1764	response to oxidative stress
OUO20_04855	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OUO20_04860	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
OUO20_04905	COG1271	oxidase subunit
OUO20_04910	COG1294	oxidase, subunit
OUO20_04915	COG4988	ABC transporter
OUO20_04925	COG1131	(ABC) transporter
OUO20_04935	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
OUO20_04955	COG1435	thymidine kinase activity
OUO20_04980	COG0756	dUTP diphosphatase activity
OUO20_05005	COG0569	domain protein
OUO20_05010	COG0531	amino acid
OUO20_05015	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OUO20_05020	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
OUO20_05025	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
OUO20_05040	COG0667	Aldo Keto reductase
OUO20_05060	COG1122	ATPase activity
OUO20_05065	COG1024	Enoyl-CoA hydratase
OUO20_05065	COG1250	3-hydroxyacyl-CoA dehydrogenase
OUO20_05100	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OUO20_05115	COG1012	belongs to the aldehyde dehydrogenase family
OUO20_05125	COG2132	Multicopper oxidase
OUO20_05150	COG3135	benzoate transporter
OUO20_05195	COG0242	peptide deformylase activity
OUO20_05200	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
OUO20_05210	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
OUO20_05225	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OUO20_05225	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OUO20_05235	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
OUO20_05240	COG0140	phosphoribosyl-ATP diphosphatase activity
OUO20_05245	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
OUO20_05250	COG0107	imidazoleglycerol-phosphate synthase activity
OUO20_05260	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
OUO20_05280	COG0134	indole-3-glycerol-phosphate synthase activity
OUO20_05285	COG0133	tryptophan synthase activity
OUO20_05290	COG0159	tryptophan synthase activity
OUO20_05295	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
OUO20_05330	COG2271	Major facilitator Superfamily
OUO20_05335	COG2272	Belongs to the type-B carboxylesterase lipase family
OUO20_05360	COG3328	transposase activity
OUO20_05365	COG1012	belongs to the aldehyde dehydrogenase family
OUO20_05370	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OUO20_05390	COG1309	transcriptional regulator
OUO20_05395	COG2365	Tyrosine phosphatase family
OUO20_05455	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
OUO20_05570	COG1349	DNA-binding transcription factor activity
OUO20_05595	COG0800	Aldolase
OUO20_05605	COG1609	Transcriptional regulator
OUO20_05640	COG0583	DNA-binding transcription factor activity
OUO20_05645	COG1012	belongs to the aldehyde dehydrogenase family
OUO20_05650	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OUO20_05665	COG0596	Alpha beta hydrolase
OUO20_05675	COG1063	alcohol dehydrogenase
OUO20_05680	COG0477	Major facilitator Superfamily
OUO20_05710	COG1970	mechanosensitive ion channel activity
OUO20_05755	COG2826	transposase and inactivated derivatives, IS30 family
OUO20_05830	COG0671	phosphoesterase, PA-phosphatase related
OUO20_05845	COG3654	unkown
OUO20_05850	COG1309	transcriptional regulator
OUO20_05875	COG1902	pentaerythritol trinitrate reductase activity
OUO20_05880	COG1609	Transcriptional regulator
OUO20_05895	COG0395	ABC-type sugar transport system, permease component
OUO20_05900	COG0395	ABC-type sugar transport system, permease component
OUO20_05920	COG0395	ABC-type sugar transport system, permease component
OUO20_05925	COG1175	transmembrane transport
OUO20_05935	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OUO20_05940	COG1621	beta-fructofuranosidase activity
OUO20_05945	COG4608	Belongs to the ABC transporter superfamily
OUO20_05950	COG0444	Belongs to the ABC transporter superfamily
OUO20_05955	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OUO20_05960	COG0601	transmembrane transport
OUO20_05965	COG0747	negative chemotaxis
OUO20_05970	COG1609	Transcriptional regulator
OUO20_05975	COG0667	Aldo Keto reductase
OUO20_05980	COG1621	beta-fructofuranosidase activity
OUO20_05990	COG1621	beta-fructofuranosidase activity
OUO20_06005	COG0395	ABC-type sugar transport system, permease component
OUO20_06010	COG4209	transmembrane transport
OUO20_06050	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
OUO20_06090	COG1063	alcohol dehydrogenase
OUO20_06100	COG4638	Rieske (2fe-2S)
OUO20_06115	COG0437	4 iron, 4 sulfur cluster binding
OUO20_06125	COG0709	Synthesizes selenophosphate from selenide and ATP
OUO20_06155	COG1082	Xylose isomerase domain protein TIM barrel
OUO20_06195	COG2124	cytochrome p450
OUO20_06225	COG0667	Aldo Keto reductase
OUO20_06235	COG2268	Band 7 protein
OUO20_06245	COG1028	Short-chain dehydrogenase reductase Sdr
OUO20_06260	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
OUO20_06275	COG0406	alpha-ribazole phosphatase activity
OUO20_06280	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
OUO20_06295	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OUO20_06300	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OUO20_06315	COG1643	Atp-dependent helicase
OUO20_06335	COG0009	L-threonylcarbamoyladenylate synthase
OUO20_06365	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
OUO20_06370	COG2050	protein possibly involved in aromatic compounds catabolism
OUO20_06380	COG4552	Acetyltransferase involved in intracellular survival and related
OUO20_06385	COG0539	negative regulation of cytoplasmic translation
OUO20_06395	COG1739	Uncharacterized protein family UPF0029
OUO20_06405	COG0556	nucleotide-excision repair
OUO20_06410	COG1653	transport
OUO20_06420	COG0477	Major facilitator Superfamily
OUO20_06440	COG4106	trans-aconitate 2-methyltransferase activity
OUO20_06470	COG0204	Acyl-transferase
OUO20_06470	COG0318	PFAM AMP-dependent synthetase and ligase
OUO20_06475	COG0322	excinuclease ABC activity
OUO20_06480	COG1660	Displays ATPase and GTPase activities
OUO20_06485	COG0391	Required for morphogenesis under gluconeogenic growth conditions
OUO20_06490	COG1481	regulation of sporulation
OUO20_06495	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
OUO20_06500	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
OUO20_06505	COG0126	phosphoglycerate kinase activity
OUO20_06510	COG0149	triose-phosphate isomerase activity
OUO20_06515	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
OUO20_06525	COG0363	glucosamine-6-phosphate deaminase activity
OUO20_06540	COG0166	Belongs to the GPI family
OUO20_06545	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
OUO20_06555	COG0109	protoheme IX farnesyltransferase activity
OUO20_06560	COG0659	secondary active sulfate transmembrane transporter activity
OUO20_06565	COG1612	heme a metabolic process
OUO20_06575	COG1131	(ABC) transporter
OUO20_06600	COG0396	ATPase activity
OUO20_06605	COG2151	metal-sulfur cluster biosynthetic enzyme
OUO20_06615	COG0318	PFAM AMP-dependent synthetase and ligase
OUO20_06625	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
OUO20_06630	COG1122	ATPase activity
OUO20_06635	COG1268	BioY protein
OUO20_06640	COG2826	transposase and inactivated derivatives, IS30 family
OUO20_06650	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OUO20_06650	COG0456	acetyltransferase
OUO20_06655	COG2329	Antibiotic biosynthesis monooxygenase
OUO20_06660	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
OUO20_06675	COG0346	lactoylglutathione lyase activity
OUO20_06680	COG2354	Protein conserved in bacteria
OUO20_06690	COG0488	(ABC) transporter
OUO20_06715	COG1028	Short-chain dehydrogenase reductase Sdr
OUO20_06720	COG1028	Short-chain dehydrogenase reductase Sdr
OUO20_06725	COG3830	Belongs to the UPF0237 family
OUO20_06725	COG0560	Phosphoserine phosphatase
OUO20_06740	COG1119	ATPase activity
OUO20_06755	COG0254	rRNA binding
OUO20_06770	COG2855	membrane
OUO20_06800	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
OUO20_06805	COG0297	glycogen (starch) synthase activity
OUO20_06845	COG0435	Glutathione S-transferase
OUO20_06880	COG1063	alcohol dehydrogenase
OUO20_06900	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OUO20_06920	COG0667	Aldo Keto reductase
OUO20_06925	COG1968	undecaprenyl-diphosphatase activity
OUO20_06930	COG0215	cysteine-tRNA ligase activity
OUO20_06940	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OUO20_06945	COG1994	Peptidase M50
OUO20_06945	COG0517	IMP dehydrogenase activity
OUO20_06960	COG4122	O-methyltransferase activity
OUO20_06970	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
OUO20_06975	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
OUO20_06980	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
OUO20_06985	COG0545	Peptidyl-prolyl cis-trans isomerase
OUO20_07005	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OUO20_07010	COG0805	protein transport
OUO20_07015	COG4581	dead DEAH box helicase
OUO20_07025	COG1216	Glycosyl transferase, family 2
OUO20_07050	COG0242	peptide deformylase activity
OUO20_07060	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OUO20_07065	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
OUO20_07070	COG3424	synthase
OUO20_07075	COG1404	Belongs to the peptidase S8 family
OUO20_07090	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
OUO20_07095	COG1845	cytochrome c oxidase, subunit III
OUO20_07100	COG2010	Cytochrome c
OUO20_07105	COG0723	plastoquinol--plastocyanin reductase activity
OUO20_07110	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
OUO20_07130	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OUO20_07135	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
OUO20_07155	COG0167	dihydroorotate dehydrogenase activity
OUO20_07170	COG1381	Involved in DNA repair and RecF pathway recombination
OUO20_07175	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OUO20_07185	COG1316	TRANSCRIPTIONal
OUO20_07190	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
OUO20_07200	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
OUO20_07215	COG1385	rRNA (uridine-N3-)-methyltransferase activity
OUO20_07220	COG0484	heat shock protein binding
OUO20_07225	COG1420	regulation of RNA biosynthetic process
OUO20_07255	COG0268	Binds directly to 16S ribosomal RNA
OUO20_07280	COG1307	EDD domain protein, DegV family
OUO20_07325	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
OUO20_07335	COG2390	Transcriptional regulator
OUO20_07340	COG0656	L-ascorbic acid biosynthetic process
OUO20_07350	COG0438	transferase activity, transferring glycosyl groups
OUO20_07360	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
OUO20_07370	COG1758	RNA polymerase activity
OUO20_07375	COG0194	GDP metabolic process
OUO20_07380	COG0194	GDP metabolic process
OUO20_07385	COG0284	orotidine-5'-phosphate decarboxylase activity
OUO20_07390	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
OUO20_07405	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
OUO20_07410	COG0540	Belongs to the ATCase OTCase family
OUO20_07425	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OUO20_07445	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
OUO20_07450	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
OUO20_07455	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
OUO20_07485	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
OUO20_07505	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
OUO20_07515	COG0124	histidyl-tRNA synthetase
OUO20_07525	COG1196	nuclear chromosome segregation
OUO20_07535	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OUO20_07540	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OUO20_07545	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OUO20_07555	COG2255	four-way junction helicase activity
OUO20_07560	COG0632	four-way junction helicase activity
OUO20_07565	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
OUO20_07570	COG0217	transcriptional regulatory protein
OUO20_07575	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
OUO20_07580	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
OUO20_07590	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OUO20_07595	COG0339	signal peptide processing
OUO20_07605	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OUO20_07635	COG1605	Chorismate mutase
OUO20_07635	COG0077	Prephenate dehydratase
OUO20_07645	COG2135	peptidase activity
OUO20_07660	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
OUO20_07665	COG1695	Transcriptional regulator
OUO20_07705	COG1028	Short-chain dehydrogenase reductase Sdr
OUO20_07740	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
OUO20_07745	COG1234	tRNA 3'-trailer cleavage
OUO20_07835	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
OUO20_07845	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OUO20_07845	COG0574	Belongs to the PEP-utilizing enzyme family
OUO20_07955	COG1842	Phage shock protein A
OUO20_07965	COG4152	abc transporter atp-binding protein
OUO20_07990	COG1175	transmembrane transport
OUO20_07995	COG0395	ABC-type sugar transport system, permease component
OUO20_08000	COG4948	Mandelate Racemase Muconate Lactonizing
OUO20_08015	COG0492	ferredoxin-NADP+ reductase activity
OUO20_08040	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OUO20_08045	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OUO20_08050	COG1780	Probably involved in ribonucleotide reductase function
OUO20_08065	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
OUO20_08080	COG0583	DNA-binding transcription factor activity
OUO20_08095	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
OUO20_08130	COG0714	Associated with various cellular activities
OUO20_08145	COG1175	transmembrane transport
OUO20_08160	COG2813	Specifically methylates the guanine in position
OUO20_08165	COG0492	ferredoxin-NADP+ reductase activity
OUO20_08170	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
OUO20_08175	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
OUO20_08200	COG0799	negative regulation of ribosome biogenesis
OUO20_08210	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
OUO20_08225	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
OUO20_08230	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
OUO20_08235	COG0211	Belongs to the bacterial ribosomal protein bL27 family
OUO20_08240	COG0261	This protein binds to 23S rRNA in the presence of protein L20
OUO20_08245	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
OUO20_08245	COG0352	thiamine-phosphate diphosphorylase activity
OUO20_08245	COG0351	phosphomethylpyrimidine kinase
OUO20_08250	COG1530	ribonuclease E activity
OUO20_08260	COG0105	UTP biosynthetic process
OUO20_08270	COG0285	dihydrofolate synthase activity
OUO20_08275	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
OUO20_08290	COG3189	MarR family transcriptional regulator
OUO20_08300	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
OUO20_08305	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
OUO20_08310	COG0740	serine-type endopeptidase activity
OUO20_08315	COG0740	serine-type endopeptidase activity
OUO20_08320	COG0544	peptidyl-prolyl cis-trans isomerase activity
OUO20_08365	COG0668	transmembrane transport
OUO20_08370	COG2346	COG2346, Truncated hemoglobins
OUO20_08380	COG1946	Acyl-CoA thioesterase
OUO20_08395	COG0629	single-stranded DNA binding
OUO20_08410	COG2115	Belongs to the xylose isomerase family
OUO20_08415	COG1070	Carbohydrate kinase
OUO20_08420	COG1082	Xylose isomerase domain protein TIM barrel
OUO20_08435	COG1609	Transcriptional regulator
OUO20_08440	COG0657	acetylesterase activity
OUO20_08440	COG2755	lipolytic protein G-D-S-L family
OUO20_08445	COG2017	converts alpha-aldose to the beta-anomer
OUO20_08460	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
OUO20_08470	COG0242	peptide deformylase activity
OUO20_08515	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
OUO20_08520	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OUO20_08535	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
OUO20_08545	COG1063	alcohol dehydrogenase
OUO20_08555	COG2084	Dehydrogenase
OUO20_08600	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OUO20_08605	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OUO20_08610	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
OUO20_08620	COG4974	Belongs to the 'phage' integrase family
OUO20_08635	COG0792	nuclease activity
OUO20_08645	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
OUO20_08655	COG0681	Belongs to the peptidase S26 family
OUO20_08660	COG0335	large ribosomal subunit rRNA binding
OUO20_08665	COG0336	Belongs to the RNA methyltransferase TrmD family
OUO20_08670	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
OUO20_08675	COG1837	Belongs to the UPF0109 family
OUO20_08680	COG0228	four-way junction DNA binding
OUO20_08690	COG2514	catechol 2,3-dioxygenase activity
OUO20_08745	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OUO20_08750	COG0318	PFAM AMP-dependent synthetase and ligase
OUO20_08755	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OUO20_08765	COG0571	ribonuclease III activity
OUO20_08770	COG0333	Belongs to the bacterial ribosomal protein bL32 family
OUO20_08780	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
OUO20_08795	COG0742	ribosomal rna small subunit methyltransferase
OUO20_08800	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
OUO20_08820	COG1181	Belongs to the D-alanine--D-alanine ligase family
OUO20_08825	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
OUO20_08835	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OUO20_08840	COG0066	3-isopropylmalate dehydratase activity
OUO20_08845	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
OUO20_08850	COG1414	Transcriptional regulator
OUO20_08890	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OUO20_08895	COG0179	Fumarylacetoacetate (FAA) hydrolase
OUO20_08900	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OUO20_08905	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OUO20_08910	COG0473	3-isopropylmalate dehydrogenase activity
OUO20_08915	COG4585	Histidine kinase
OUO20_08920	COG2197	response regulator
OUO20_08925	COG1136	(ABC) transporter
OUO20_08925	COG0577	efflux transmembrane transporter activity
OUO20_08940	COG0577	efflux transmembrane transporter activity
OUO20_08940	COG1136	(ABC) transporter
OUO20_08950	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
OUO20_08955	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
OUO20_08960	COG0440	acetolactate synthase activity
OUO20_08970	COG0129	dihydroxy-acid dehydratase activity
OUO20_08975	COG0088	Forms part of the polypeptide exit tunnel
OUO20_09010	COG0747	negative chemotaxis
OUO20_09015	COG0579	oxidoreductase
OUO20_09025	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OUO20_09035	COG1305	Transglutaminase-like
OUO20_09055	COG1104	cysteine desulfurase activity
OUO20_09065	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
OUO20_09070	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
OUO20_09080	COG1113	amino acid transport
OUO20_09095	COG0477	Major facilitator Superfamily
OUO20_09110	COG0419	ATPase involved in DNA repair
OUO20_09115	COG0420	3'-5' exonuclease activity
OUO20_09140	COG0586	Pfam SNARE associated Golgi protein
OUO20_09145	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
OUO20_09150	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
OUO20_09155	COG1234	tRNA 3'-trailer cleavage
OUO20_09160	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
OUO20_09170	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
OUO20_09180	COG1335	isochorismatase
OUO20_09195	COG0363	glucosamine-6-phosphate deaminase activity
OUO20_09250	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
OUO20_09265	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
OUO20_09275	COG0355	proton-transporting ATP synthase activity, rotational mechanism
OUO20_09280	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
OUO20_09290	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
OUO20_09295	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OUO20_09300	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
OUO20_09305	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OUO20_09310	COG0356	it plays a direct role in the translocation of protons across the membrane
OUO20_09345	COG2890	protein-(glutamine-N5) methyltransferase activity
OUO20_09350	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
OUO20_09360	COG0083	homoserine kinase activity
OUO20_09365	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
OUO20_09375	COG0019	diaminopimelate decarboxylase activity
OUO20_09380	COG0018	arginyl-trna synthetase
OUO20_09395	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OUO20_09395	COG1017	nitric oxide dioxygenase activity
OUO20_09430	COG1643	Atp-dependent helicase
OUO20_09435	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OUO20_09440	COG0537	adenosine 5'-monophosphoramidase activity
OUO20_09445	COG1064	alcohol dehydrogenase
OUO20_09455	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
OUO20_09460	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
OUO20_09475	COG1121	(ABC) transporter
OUO20_09480	COG0803	Belongs to the bacterial solute-binding protein 9 family
OUO20_09495	COG0567	Dehydrogenase, E1 component
OUO20_09495	COG0508	dehydrogenase complex catalyzes the overall conversion of
OUO20_09520	COG1595	DNA-templated transcription, initiation
OUO20_09540	COG0483	inositol monophosphate 1-phosphatase activity
OUO20_09560	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OUO20_09565	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OUO20_09575	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OUO20_09625	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
OUO20_09640	COG2884	Cell division ATP-binding protein ftsE
OUO20_09645	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
OUO20_09725	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
OUO20_09730	COG1088	dTDP-glucose 4,6-dehydratase activity
OUO20_09820	COG1216	Glycosyl transferase, family 2
OUO20_09855	COG2902	Dehydrogenase
OUO20_09900	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
OUO20_09910	COG5401	PFAM Sporulation and spore germination
OUO20_09915	COG5002	protein histidine kinase activity
OUO20_09940	COG0714	Associated with various cellular activities
OUO20_09970	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OUO20_09975	COG0601	transmembrane transport
OUO20_10010	COG0484	heat shock protein binding
OUO20_10015	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
OUO20_10035	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
OUO20_10040	COG2086	electron transfer activity
OUO20_10045	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OUO20_10055	COG1842	Phage shock protein A
OUO20_10060	COG0415	Belongs to the DNA photolyase family
OUO20_10080	COG1615	UPF0182 protein
OUO20_10085	COG3480	Lon protease (S16) C-terminal proteolytic domain
OUO20_10110	COG2816	NAD+ diphosphatase activity
OUO20_10140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OUO20_10145	COG0765	amino acid transport
OUO20_10150	COG1126	abc transporter atp-binding protein
OUO20_10165	COG0113	porphobilinogen synthase activity
OUO20_10175	COG0181	hydroxymethylbilane synthase activity
OUO20_10180	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
OUO20_10185	COG3253	May function as heme-dependent peroxidase
OUO20_10195	COG1231	oxidoreductase activity
OUO20_10200	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
OUO20_10205	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
OUO20_10230	COG2022	thiamine diphosphate biosynthetic process
OUO20_10240	COG2022	thiamine diphosphate biosynthetic process
OUO20_10240	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OUO20_10245	COG0352	thiamine-phosphate diphosphorylase activity
OUO20_10255	COG0513	Belongs to the DEAD box helicase family
OUO20_10260	COG2189	Belongs to the N(4) N(6)-methyltransferase family
OUO20_10265	COG0613	PHP domain protein
OUO20_10270	COG0006	proline dipeptidase activity
OUO20_10295	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OUO20_10310	COG1595	DNA-templated transcription, initiation
OUO20_10330	COG3599	regulation of cell shape
OUO20_10340	COG1126	abc transporter atp-binding protein
OUO20_10345	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OUO20_10350	COG0765	amino acid transport
OUO20_10355	COG0765	amino acid transport
OUO20_10360	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OUO20_10365	COG2171	N-acyltransferase activity
OUO20_10380	COG3226	Transcriptional regulator
OUO20_10385	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
OUO20_10415	COG1217	gtp-binding protein TYPA
OUO20_10430	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OUO20_10440	COG4166	transmembrane transport
OUO20_10450	COG0012	GTP binding
OUO20_10455	COG1322	Protein conserved in bacteria
OUO20_10470	COG1570	exodeoxyribonuclease VII activity
OUO20_10475	COG1722	exodeoxyribonuclease VII activity
OUO20_10480	COG2326	polyphosphate kinase activity
OUO20_10495	COG1174	glycine betaine transport
OUO20_10500	COG1174	glycine betaine transport
OUO20_10520	COG0583	DNA-binding transcription factor activity
OUO20_10525	COG2814	Major facilitator Superfamily
OUO20_10530	COG2814	Major facilitator Superfamily
OUO20_10550	COG0598	Magnesium transport protein CorA
OUO20_10580	COG1210	Utp--glucose-1-phosphate uridylyltransferase
OUO20_10585	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
OUO20_10610	COG0518	GMP synthase (glutamine-hydrolyzing) activity
OUO20_10610	COG0519	Catalyzes the synthesis of GMP from XMP
OUO20_10615	COG3415	Transposase
OUO20_10615	COG2801	Transposase and inactivated derivatives
OUO20_10635	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
OUO20_10640	COG0516	GMP reductase activity
OUO20_10655	COG1621	beta-fructofuranosidase activity
OUO20_10695	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
OUO20_10695	COG2755	lipolytic protein G-D-S-L family
OUO20_10715	COG0459	protein refolding
OUO20_10720	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
OUO20_10735	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
OUO20_10740	COG1472	Belongs to the glycosyl hydrolase 3 family
OUO20_10745	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
OUO20_10750	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
OUO20_10755	COG0456	acetyltransferase
OUO20_10755	COG1214	PFAM Peptidase M22, glycoprotease
OUO20_10765	COG0802	atpase or kinase
OUO20_10770	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OUO20_10775	COG1105	Belongs to the carbohydrate kinase PfkB family
OUO20_10785	COG0438	transferase activity, transferring glycosyl groups
OUO20_10805	COG0667	Aldo Keto reductase
OUO20_10830	COG0736	holo-[acyl-carrier-protein] synthase activity
OUO20_10840	COG1072	(Pantothenic acid kinase))
OUO20_10845	COG1876	peptidase activity
OUO20_10850	COG1970	mechanosensitive ion channel activity
OUO20_10855	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OUO20_10865	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
OUO20_10870	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
OUO20_10870	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
OUO20_10875	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
OUO20_10880	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
OUO20_10915	COG0455	bacterial-type flagellum organization
OUO20_10960	COG2894	cell division
OUO20_10995	COG0101	tRNA pseudouridine synthase activity
OUO20_11000	COG0203	ribosomal protein L17
OUO20_11005	COG0202	RNA polymerase activity
OUO20_11010	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
OUO20_11015	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
OUO20_11020	COG0257	Belongs to the bacterial ribosomal protein bL36 family
OUO20_11025	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
OUO20_11030	COG3191	aminopeptidase activity
OUO20_11055	COG0563	adenylate kinase activity
OUO20_11065	COG0200	Binds to the 23S rRNA
OUO20_11070	COG1841	ribosomal large subunit assembly
OUO20_11075	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
OUO20_11080	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
OUO20_11085	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
OUO20_11090	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
OUO20_11095	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
OUO20_11100	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
OUO20_11105	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
OUO20_11110	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
OUO20_11120	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
OUO20_11125	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
OUO20_11130	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
OUO20_11135	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
OUO20_11140	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
OUO20_11145	COG0089	rRNA binding
OUO20_11150	COG0088	Forms part of the polypeptide exit tunnel
OUO20_11155	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
OUO20_11160	COG0051	transcription antitermination factor activity, RNA binding
OUO20_11180	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
OUO20_11185	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
OUO20_11190	COG0049	tRNA binding
OUO20_11195	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
OUO20_11200	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OUO20_11205	COG0085	RNA polymerase activity
OUO20_11215	COG0183	Belongs to the thiolase family
OUO20_11220	COG0442	prolyl-tRNA aminoacylation
OUO20_11225	COG0222	ribosome binding
OUO20_11230	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
OUO20_11245	COG0081	regulation of translation
OUO20_11250	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
OUO20_11275	COG2197	response regulator
OUO20_11330	COG3485	protocatechuate 3,4-dioxygenase
OUO20_11340	COG0745	RESPONSE REGULATOR receiver
OUO20_11345	COG0456	acetyltransferase
OUO20_11350	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
OUO20_11360	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
OUO20_11365	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
OUO20_11385	COG1733	regulation of RNA biosynthetic process
OUO20_11395	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
OUO20_11410	COG0812	UDP-N-acetylmuramate dehydrogenase activity
OUO20_11415	COG0738	Major facilitator superfamily
OUO20_11425	COG2030	dehydratase
OUO20_11445	COG4989	oxidoreductase activity
OUO20_11450	COG0366	Alpha amylase catalytic
OUO20_11455	COG1940	carbohydrate kinase activity
OUO20_11460	COG0702	epimerase
OUO20_11470	COG1140	nitrate reductase beta subunit
OUO20_11495	COG0706	membrane insertase activity
OUO20_11535	COG0754	glutathionylspermidine amidase activity
OUO20_11575	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
OUO20_11615	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OUO20_11625	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OUO20_11650	COG1666	GTP binding
OUO20_11655	COG0672	)-iron permease
OUO20_11665	COG2837	iron assimilation
OUO20_11695	COG0531	amino acid
OUO20_11760	COG3835	regulator
OUO20_11775	COG2186	Transcriptional regulator
OUO20_11815	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
OUO20_11815	COG1648	precorrin-2 dehydrogenase activity
OUO20_11830	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
OUO20_11840	COG1690	Belongs to the RtcB family
OUO20_11845	COG2895	sulfate adenylyltransferase (ATP) activity
OUO20_11860	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OUO20_11885	COG0142	geranyltranstransferase activity
OUO20_11895	COG2226	methyltransferase
OUO20_11900	COG1169	isochorismate synthase
OUO20_11910	COG0765	amino acid transport
OUO20_11920	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
OUO20_11945	COG0598	Magnesium transport protein CorA
OUO20_11955	COG3559	Exporter of polyketide antibiotics
OUO20_11965	COG1131	(ABC) transporter
OUO20_12015	COG2072	flavoprotein involved in K transport
OUO20_12060	COG0492	ferredoxin-NADP+ reductase activity
OUO20_12065	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OUO20_12105	COG1316	TRANSCRIPTIONal
OUO20_12125	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
OUO20_12125	COG2755	lipolytic protein G-D-S-L family
OUO20_12140	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OUO20_12145	COG3795	YCII-related domain
OUO20_12150	COG4941	Belongs to the sigma-70 factor family
OUO20_12170	COG0508	dehydrogenase complex catalyzes the overall conversion of
OUO20_12175	COG0022	dehydrogenase e1 component
OUO20_12245	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OUO20_12255	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OUO20_12265	COG1063	alcohol dehydrogenase
OUO20_12270	COG2017	converts alpha-aldose to the beta-anomer
OUO20_12300	COG0028	Belongs to the TPP enzyme family
OUO20_12345	COG0584	glycerophosphoryl diester phosphodiesterase
OUO20_12350	COG0596	Alpha beta hydrolase
OUO20_12400	COG0076	glutamate decarboxylase activity
OUO20_12410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OUO20_12415	COG0765	amino acid transport
OUO20_12425	COG1304	FMN binding
OUO20_12485	COG0489	protein tyrosine kinase activity
OUO20_12515	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OUO20_12545	COG1210	Utp--glucose-1-phosphate uridylyltransferase
OUO20_12555	COG0489	protein tyrosine kinase activity
OUO20_12580	COG1620	l-lactate permease
OUO20_12590	COG2188	Transcriptional regulator
OUO20_12595	COG0277	FAD linked oxidase domain protein
OUO20_12600	COG1620	l-lactate permease
OUO20_12605	COG1620	l-lactate permease
OUO20_12610	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
OUO20_12615	COG1024	Enoyl-CoA hydratase
OUO20_12620	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OUO20_12625	COG2151	metal-sulfur cluster biosynthetic enzyme
OUO20_12630	COG3396	Phenylacetate-CoA oxygenase
OUO20_12635	COG3460	Phenylacetate-CoA oxygenase
OUO20_12640	COG3396	Phenylacetate-CoA oxygenase
OUO20_12695	COG0667	Aldo Keto reductase
OUO20_12700	COG0300	oxidoreductase activity
OUO20_12720	COG0640	Transcriptional regulator
OUO20_12730	COG0456	acetyltransferase
OUO20_12730	COG1214	PFAM Peptidase M22, glycoprotease
OUO20_12760	COG0390	transport system, permease component
OUO20_12790	COG1937	Protein conserved in bacteria
OUO20_12795	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OUO20_12810	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OUO20_12820	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OUO20_12840	COG0508	dehydrogenase complex catalyzes the overall conversion of
OUO20_12845	COG0508	dehydrogenase complex catalyzes the overall conversion of
OUO20_12845	COG0022	dehydrogenase e1 component
OUO20_12850	COG0508	dehydrogenase complex catalyzes the overall conversion of
OUO20_12850	COG0022	dehydrogenase e1 component
OUO20_12855	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
OUO20_12860	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OUO20_12915	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
OUO20_12930	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
OUO20_12935	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OUO20_12950	COG3842	ATPase activity
OUO20_12960	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
OUO20_12970	COG2217	Heavy metal translocating P-type atpase
OUO20_12985	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OUO20_12990	COG1316	TRANSCRIPTIONal
OUO20_13000	COG0588	phosphoglycerate mutase activity
OUO20_13005	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
OUO20_13010	COG0071	Belongs to the small heat shock protein (HSP20) family
OUO20_13045	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
OUO20_13070	COG4948	Mandelate Racemase Muconate Lactonizing
OUO20_13075	COG1802	Transcriptional regulator
OUO20_13085	COG2271	Major facilitator Superfamily
OUO20_13090	COG0857	belongs to the CobB CobQ family
OUO20_13090	COG0280	phosphate acetyltransferase
OUO20_13095	COG2050	protein possibly involved in aromatic compounds catabolism
OUO20_13110	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OUO20_13125	COG1012	belongs to the aldehyde dehydrogenase family
OUO20_13125	COG2030	dehydratase
OUO20_13130	COG2050	protein possibly involved in aromatic compounds catabolism
OUO20_13160	COG2755	lipolytic protein G-D-S-L family
OUO20_13175	COG1250	3-hydroxyacyl-CoA dehydrogenase
OUO20_13180	COG1024	Enoyl-CoA hydratase
OUO20_13215	COG2146	nitrite reductase [NAD(P)H] activity
OUO20_13220	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OUO20_13230	COG1266	CAAX protease self-immunity
OUO20_13240	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
OUO20_13290	COG0443	Heat shock 70 kDa protein
OUO20_13295	COG0443	Heat shock 70 kDa protein
OUO20_13300	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
OUO20_13310	COG0785	Cytochrome C biogenesis protein
OUO20_13315	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OUO20_13320	COG0406	alpha-ribazole phosphatase activity
OUO20_13335	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
OUO20_13360	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
OUO20_13365	COG3458	cephalosporin-C deacetylase activity
OUO20_13370	COG1070	Carbohydrate kinase
OUO20_13375	COG1028	Short-chain dehydrogenase reductase Sdr
OUO20_13375	COG3347	Dehydrogenase
OUO20_13390	COG1609	Transcriptional regulator
OUO20_13415	COG2755	lipolytic protein G-D-S-L family
OUO20_13420	COG0395	ABC-type sugar transport system, permease component
OUO20_13425	COG4209	transmembrane transport
OUO20_13430	COG1653	transport
OUO20_13435	COG5578	integral membrane protein
OUO20_13460	COG2814	Major facilitator Superfamily
OUO20_13470	COG0395	ABC-type sugar transport system, permease component
OUO20_13475	COG1175	transmembrane transport
OUO20_13495	COG0395	ABC-type sugar transport system, permease component
OUO20_13500	COG1175	transmembrane transport
OUO20_13530	COG4948	Mandelate Racemase Muconate Lactonizing
OUO20_13535	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OUO20_13545	COG0673	inositol 2-dehydrogenase activity
OUO20_13570	COG0123	including yeast histone deacetylase and acetoin utilization protein
OUO20_13575	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
OUO20_13580	COG0569	domain protein
OUO20_13590	COG0248	Ppx GppA phosphatase
OUO20_13600	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OUO20_13600	COG1754	DNA topoisomerase type I activity
OUO20_13605	COG2890	protein-(glutamine-N5) methyltransferase activity
OUO20_13785	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OUO20_13790	COG1349	DNA-binding transcription factor activity
OUO20_13805	COG4209	transmembrane transport
OUO20_13810	COG0395	ABC-type sugar transport system, permease component
OUO20_13825	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
OUO20_13845	COG0395	ABC-type sugar transport system, permease component
OUO20_13850	COG1175	transmembrane transport
OUO20_13860	COG1609	Transcriptional regulator
OUO20_13885	COG1408	metallophosphoesterase
OUO20_13890	COG1132	(ABC) transporter
OUO20_13895	COG1132	(ABC) transporter
OUO20_13915	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
OUO20_13950	COG1953	Uracil, thiamine, allantoin
OUO20_13960	COG2070	2-Nitropropane dioxygenase
OUO20_13985	COG0667	Aldo Keto reductase
OUO20_13990	COG1529	Aldehyde oxidase and xanthine dehydrogenase
OUO20_13990	COG2080	2 iron, 2 sulfur cluster binding
OUO20_14000	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
OUO20_14000	COG3608	succinylglutamate desuccinylase aspartoacylase
OUO20_14005	COG2252	PERMEase
OUO20_14010	COG0590	tRNA wobble adenosine to inosine editing
OUO20_14020	COG3285	dna ligase
OUO20_14020	COG1793	dna ligase
OUO20_14050	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
OUO20_14060	COG3257	ureidoglycine aminohydrolase activity
OUO20_14085	COG3387	PFAM Glycoside hydrolase 15-related
OUO20_14110	COG0484	heat shock protein binding
OUO20_14115	COG0071	Belongs to the small heat shock protein (HSP20) family
OUO20_14120	COG0789	Transcriptional regulator
OUO20_14135	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OUO20_14140	COG0563	adenylate kinase activity
OUO20_14150	COG0745	RESPONSE REGULATOR receiver
OUO20_14155	COG2267	carboxylic ester hydrolase activity
OUO20_14160	COG0640	Transcriptional regulator
OUO20_14180	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OUO20_14275	COG2070	2-Nitropropane dioxygenase
OUO20_14280	COG1064	alcohol dehydrogenase
OUO20_14300	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OUO20_14310	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OUO20_14330	COG3739	integral membrane protein
OUO20_14345	COG0129	dihydroxy-acid dehydratase activity
OUO20_14385	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
OUO20_14400	COG0477	Major facilitator Superfamily
OUO20_14425	COG0640	Transcriptional regulator
OUO20_14435	COG3866	Pectate lyase
OUO20_14440	COG2755	lipolytic protein G-D-S-L family
OUO20_14445	COG1053	succinate dehydrogenase
OUO20_14450	COG1053	succinate dehydrogenase
OUO20_14470	COG1902	pentaerythritol trinitrate reductase activity
OUO20_14470	COG0446	pyridine nucleotide-disulphide oxidoreductase
OUO20_14485	COG1028	Short-chain dehydrogenase reductase Sdr
OUO20_14490	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
OUO20_14495	COG0477	Major facilitator Superfamily
OUO20_14500	COG0583	DNA-binding transcription factor activity
OUO20_14530	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OUO20_14535	COG2271	Major facilitator Superfamily
OUO20_14580	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
OUO20_14585	COG4251	negative regulation of phosphorylation
OUO20_14600	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OUO20_14615	COG4585	Histidine kinase
OUO20_14625	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OUO20_14635	COG4585	Histidine kinase
OUO20_14660	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
OUO20_14670	COG0477	Major facilitator Superfamily
OUO20_14690	COG3401	FG-GAP repeat protein
OUO20_14700	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
OUO20_14725	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
OUO20_14740	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
OUO20_14745	COG1301	dicarboxylic acid transport
OUO20_14755	COG1414	Transcriptional regulator
OUO20_14760	COG2814	Major facilitator Superfamily
OUO20_14765	COG1609	Transcriptional regulator
OUO20_14770	COG1263	PTS System
OUO20_14770	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OUO20_14770	COG2190	(PTS) system
OUO20_14775	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OUO20_14780	COG1263	PTS System
OUO20_14805	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OUO20_14825	COG1301	dicarboxylic acid transport
OUO20_14840	COG0477	Major facilitator Superfamily
OUO20_14850	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OUO20_14860	COG1609	Transcriptional regulator
OUO20_14865	COG0395	ABC-type sugar transport system, permease component
OUO20_14885	COG3622	Belongs to the hyi family
OUO20_14890	COG2084	Dehydrogenase
OUO20_14895	COG3960	tartronate-semialdehyde synthase activity
OUO20_14900	COG1929	Belongs to the glycerate kinase type-1 family
OUO20_14935	COG0745	RESPONSE REGULATOR receiver
OUO20_14945	COG1366	Belongs to the anti-sigma-factor antagonist family
OUO20_14970	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OUO20_15005	COG1802	Transcriptional regulator
OUO20_15020	COG3404	Formiminotransferase-cyclodeaminase
OUO20_15025	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
OUO20_15035	COG2271	Major facilitator Superfamily
OUO20_15055	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OUO20_15075	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
OUO20_15115	COG3585	molybdate ion transport
OUO20_15140	COG0135	phosphoribosylanthranilate isomerase activity
OUO20_15155	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
OUO20_15185	COG1940	carbohydrate kinase activity
OUO20_15195	COG2076	Multidrug Resistance protein
OUO20_15205	COG0667	Aldo Keto reductase
OUO20_15225	COG0500	methyltransferase
OUO20_15235	COG2807	transmembrane transport
OUO20_15245	COG0220	tRNA (guanine-N7-)-methyltransferase activity
OUO20_15305	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
OUO20_15330	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OUO20_15335	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OUO20_15340	COG0069	glutamate synthase activity
OUO20_15345	COG2218	PFAM glutamate synthase alpha subunit domain protein
OUO20_15350	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
OUO20_15385	COG1609	Transcriptional regulator
OUO20_15405	COG1175	transmembrane transport
OUO20_15410	COG0395	ABC-type sugar transport system, permease component
OUO20_15445	COG3226	Transcriptional regulator
OUO20_15470	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
OUO20_15505	COG1760	l-serine dehydratase
OUO20_15530	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
OUO20_15540	COG1846	Transcriptional regulator
OUO20_15540	COG1940	carbohydrate kinase activity
OUO20_15550	COG1175	transmembrane transport
OUO20_15555	COG0395	ABC-type sugar transport system, permease component
OUO20_15605	COG3971	2-oxopent-4-enoate hydratase activity
OUO20_15625	COG1012	belongs to the aldehyde dehydrogenase family
OUO20_15635	COG0789	Transcriptional regulator
OUO20_15640	COG0484	heat shock protein binding
OUO20_15645	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
OUO20_15650	COG0443	Heat shock 70 kDa protein
OUO20_15670	COG2409	Drug exporters of the RND superfamily
OUO20_15695	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OUO20_15705	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OUO20_15750	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
OUO20_15755	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OUO20_15765	COG1122	ATPase activity
OUO20_15770	COG4721	ABC-type cobalt transport system, permease component
OUO20_15775	COG4702	Belongs to the UPF0303 family
OUO20_15800	COG2212	antiporter activity
OUO20_15815	COG1006	Multisubunit Na H antiporter MnhC subunit
OUO20_15820	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OUO20_15820	COG2111	Na H antiporter
OUO20_15835	COG0475	glutathione-regulated potassium exporter activity
OUO20_15870	COG0583	DNA-binding transcription factor activity
OUO20_15880	COG1012	belongs to the aldehyde dehydrogenase family
OUO20_15885	COG0531	amino acid
OUO20_15890	COG0583	DNA-binding transcription factor activity
OUO20_15895	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
OUO20_15910	COG2814	Major facilitator Superfamily
OUO20_15915	COG3387	PFAM Glycoside hydrolase 15-related
OUO20_15920	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OUO20_15925	COG0667	Aldo Keto reductase
OUO20_15940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OUO20_15950	COG1012	belongs to the aldehyde dehydrogenase family
OUO20_15970	COG3845	ABC transporter
OUO20_15995	COG1609	Transcriptional regulator
OUO20_16005	COG0800	Aldolase
OUO20_16020	COG0646	methionine synthase
OUO20_16020	COG1410	methionine synthase
OUO20_16055	COG1002	Type II restriction enzyme, methylase subunits
OUO20_16070	COG2267	carboxylic ester hydrolase activity
OUO20_16075	COG3265	gluconokinase activity
OUO20_16085	COG2084	Dehydrogenase
OUO20_16090	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
OUO20_16095	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
OUO20_16115	COG0726	polysaccharide deacetylase
OUO20_16140	COG1802	Transcriptional regulator
OUO20_16150	COG3842	ATPase activity
OUO20_16160	COG1840	ABC-type Fe3 transport system, periplasmic component
OUO20_16170	COG0583	DNA-binding transcription factor activity
OUO20_16175	COG2828	Protein conserved in bacteria
OUO20_16180	COG1301	dicarboxylic acid transport
OUO20_16190	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OUO20_16195	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OUO20_16215	COG0765	amino acid transport
OUO20_16250	COG3336	cytochrome c oxidase
OUO20_16255	COG0776	regulation of translation
OUO20_16285	COG1609	Transcriptional regulator
OUO20_16305	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
OUO20_16310	COG0267	Belongs to the bacterial ribosomal protein bL33 family
OUO20_16315	COG0227	Belongs to the bacterial ribosomal protein bL28 family
OUO20_16365	COG1120	ATPase activity
OUO20_16375	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OUO20_16425	COG3012	SEC-C Motif Domain Protein
OUO20_16435	COG0667	Aldo Keto reductase
OUO20_16475	COG0671	phosphoesterase, PA-phosphatase related
OUO20_16480	COG0586	Pfam SNARE associated Golgi protein
OUO20_16485	COG2186	Transcriptional regulator
OUO20_16495	COG1027	Aspartate ammonia-lyase
OUO20_16505	COG0405	Gamma-glutamyltransferase
OUO20_16510	COG0039	L-malate dehydrogenase activity
OUO20_16515	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OUO20_16530	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OUO20_16555	COG1280	lysine exporter protein (LysE YggA)
OUO20_16575	COG0281	malic enzyme
OUO20_16580	COG1309	transcriptional regulator
OUO20_16595	COG0477	Major facilitator Superfamily
OUO20_16600	COG0477	Major facilitator Superfamily
OUO20_16620	COG0246	Mannitol dehydrogenase
OUO20_16625	COG2213	PTS system mannitol-specific
OUO20_16625	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
OUO20_16655	COG0686	Belongs to the AlaDH PNT family
OUO20_16660	COG0673	inositol 2-dehydrogenase activity
OUO20_16695	COG0431	NADPH-dependent FMN reductase
OUO20_16710	COG0589	response to stress
OUO20_16725	COG0508	dehydrogenase complex catalyzes the overall conversion of
OUO20_16730	COG0022	dehydrogenase e1 component
OUO20_16740	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
OUO20_16775	COG0406	alpha-ribazole phosphatase activity
OUO20_16780	COG0515	serine threonine protein kinase
OUO20_16780	COG2815	serine threonine protein kinase
OUO20_16800	COG1607	acyl-coa hydrolase
OUO20_16805	COG1840	ABC-type Fe3 transport system, periplasmic component
OUO20_16810	COG3842	ATPase activity
OUO20_16815	COG1178	ABC-type Fe3 transport system permease component
OUO20_16820	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OUO20_16835	COG1414	Transcriptional regulator
OUO20_16840	COG2814	Major facilitator Superfamily
OUO20_16855	COG2271	Major facilitator Superfamily
OUO20_16860	COG1802	Transcriptional regulator
OUO20_16900	COG1414	Transcriptional regulator
OUO20_16905	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
OUO20_16910	COG0477	Major facilitator Superfamily
OUO20_16920	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
OUO20_16930	COG0183	Belongs to the thiolase family
OUO20_16935	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OUO20_16950	COG3485	protocatechuate 3,4-dioxygenase
OUO20_16955	COG3485	protocatechuate 3,4-dioxygenase
OUO20_16965	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
OUO20_16970	COG1414	Transcriptional regulator
OUO20_16975	COG0477	Major facilitator Superfamily
OUO20_16980	COG1793	dna ligase
OUO20_17000	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
OUO20_17030	COG1937	Protein conserved in bacteria
OUO20_17055	COG0697	spore germination
OUO20_17080	COG2259	Doxx family
OUO20_17115	COG0384	phenazine biosynthesis protein PhzF
OUO20_17120	COG0359	binds to the 23S rRNA
OUO20_17125	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
OUO20_17135	COG0360	Binds together with S18 to 16S ribosomal RNA
OUO20_17200	COG0463	Glycosyl transferase, family 2
OUO20_17220	COG1113	amino acid transport
OUO20_17250	COG0488	(ABC) transporter
OUO20_17255	COG0768	penicillin binding
OUO20_17280	COG0406	alpha-ribazole phosphatase activity
OUO20_17285	COG0617	tRNA 3'-terminal CCA addition
OUO20_17305	COG0492	ferredoxin-NADP+ reductase activity
OUO20_17310	COG3118	belongs to the thioredoxin family
OUO20_17320	COG1192	Involved in chromosome partitioning
OUO20_17325	COG0357	Ribosomal RNA small subunit methyltransferase G
OUO20_17335	COG0706	membrane insertase activity
OUO20_17340	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
OUO20_17345	COG0594	ribonuclease P activity
OUO20_17350	COG0230	Belongs to the bacterial ribosomal protein bL34 family
OUO20_17355	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
OUO20_17365	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
OUO20_17370	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
OUO20_17380	COG0187	DNA topoisomerase II activity
OUO20_17385	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
OUO20_17390	COG3266	domain, Protein
OUO20_17415	COG1215	transferase activity, transferring glycosyl groups
OUO20_17435	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OUO20_17440	COG2818	Glycosylase
OUO20_17450	COG3764	Sortase (surface protein transpeptidase)
OUO20_17465	COG0515	serine threonine protein kinase
OUO20_17465	COG2815	serine threonine protein kinase
OUO20_17490	COG1716	ATPase activity
OUO20_17495	COG1716	ATPase activity
OUO20_17545	COG0346	lactoylglutathione lyase activity
OUO20_17590	COG0277	FAD linked oxidase domain protein
OUO20_17595	COG1357	PFAM Pentapeptide repeats (8 copies)
OUO20_17605	COG2957	Belongs to the agmatine deiminase family
OUO20_17655	COG1175	transmembrane transport
OUO20_17660	COG1653	transport
OUO20_17670	COG4948	Mandelate Racemase Muconate Lactonizing
OUO20_17690	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OUO20_17695	COG0765	amino acid transport
OUO20_17700	COG1126	abc transporter atp-binding protein
OUO20_17705	COG0673	inositol 2-dehydrogenase activity
OUO20_17715	COG0659	secondary active sulfate transmembrane transporter activity
OUO20_17745	COG2084	Dehydrogenase
OUO20_17790	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
OUO20_17820	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
OUO20_17845	COG0477	Major facilitator Superfamily
OUO20_17855	COG0179	Fumarylacetoacetate (FAA) hydrolase
OUO20_17860	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
OUO20_17870	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
OUO20_17895	COG0154	amidase activity
OUO20_17910	COG2271	Major facilitator Superfamily
OUO20_17980	COG1355	regulation of microtubule-based process
OUO20_18005	COG3387	PFAM Glycoside hydrolase 15-related
OUO20_18010	COG1012	belongs to the aldehyde dehydrogenase family
OUO20_18025	COG4638	Rieske (2fe-2S)
OUO20_18040	COG2807	transmembrane transport
OUO20_18050	COG2801	Transposase and inactivated derivatives
OUO20_18085	COG3119	arylsulfatase activity
OUO20_18115	COG0395	ABC-type sugar transport system, permease component
OUO20_18130	COG1609	Transcriptional regulator
OUO20_18135	COG1621	beta-fructofuranosidase activity
OUO20_18180	COG0395	ABC-type sugar transport system, permease component
OUO20_18185	COG3622	Belongs to the hyi family
OUO20_18215	COG0673	inositol 2-dehydrogenase activity
OUO20_18235	COG1940	carbohydrate kinase activity
OUO20_18255	COG0477	Major facilitator Superfamily
OUO20_18285	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OUO20_18295	COG0179	Fumarylacetoacetate (FAA) hydrolase
OUO20_18310	COG0765	amino acid transport
OUO20_18315	COG0765	amino acid transport
OUO20_18320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OUO20_18325	COG1126	abc transporter atp-binding protein
OUO20_18345	COG0436	Aminotransferase
OUO20_18365	COG0596	Alpha beta hydrolase
OUO20_18395	COG1028	Short-chain dehydrogenase reductase Sdr
OUO20_18400	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OUO20_18425	COG1129	ABC transporter
OUO20_18430	COG1172	Belongs to the binding-protein-dependent transport system permease family
OUO20_18435	COG1172	Belongs to the binding-protein-dependent transport system permease family
OUO20_18445	COG1012	belongs to the aldehyde dehydrogenase family
OUO20_18450	COG1454	alcohol dehydrogenase
OUO20_18455	COG1053	succinate dehydrogenase
OUO20_18455	COG3976	FMN-binding domain protein
OUO20_18460	COG1902	pentaerythritol trinitrate reductase activity
OUO20_18465	COG1028	Short-chain dehydrogenase reductase Sdr
OUO20_18480	COG1309	transcriptional regulator
OUO20_18485	COG2807	transmembrane transport
OUO20_18550	COG1957	nucleoside hydrolase
OUO20_18555	COG0477	Major facilitator Superfamily
OUO20_18560	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OUO20_18565	COG1609	Transcriptional regulator
OUO20_18570	COG0395	ABC-type sugar transport system, permease component
OUO20_18575	COG1175	transmembrane transport
OUO20_18590	COG1621	beta-fructofuranosidase activity
OUO20_18595	COG1028	Short-chain dehydrogenase reductase Sdr
OUO20_18620	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OUO20_18630	COG0561	phosphatase activity
OUO20_18655	COG2200	EAL domain
OUO20_18655	COG2199	diguanylate cyclase activity
OUO20_18665	COG5002	protein histidine kinase activity
OUO20_18680	COG1028	Short-chain dehydrogenase reductase Sdr
OUO20_18685	COG1929	Belongs to the glycerate kinase type-1 family
OUO20_18700	COG1028	Short-chain dehydrogenase reductase Sdr
OUO20_18715	COG0823	Involved in the tonB-independent uptake of proteins
OUO20_18725	COG0673	inositol 2-dehydrogenase activity
OUO20_18730	COG0673	inositol 2-dehydrogenase activity
OUO20_18740	COG0395	ABC-type sugar transport system, permease component
OUO20_18785	COG2233	PERMEase
OUO20_18790	COG0778	Nitroreductase
OUO20_18810	COG0583	DNA-binding transcription factor activity
OUO20_18825	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
OUO20_18830	COG2186	Transcriptional regulator
OUO20_18840	COG1804	L-carnitine dehydratase bile acid-inducible protein F
OUO20_18855	COG5416	Lipopolysaccharide assembly protein A domain
OUO20_18870	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OUO20_18890	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
OUO20_18900	COG0561	phosphatase activity
OUO20_18955	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OUO20_18960	COG0302	gtp cyclohydrolase
OUO20_18965	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
OUO20_18970	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
OUO20_19000	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
OUO20_19020	COG0693	protein deglycase activity
OUO20_19025	COG2814	Major facilitator Superfamily
OUO20_19035	COG1309	transcriptional regulator
OUO20_19050	COG3665	Urea carboxylase-associated protein
OUO20_19075	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
OUO20_19100	COG0823	Involved in the tonB-independent uptake of proteins
OUO20_19100	COG1506	peptidase
OUO20_19105	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
OUO20_19110	COG2376	Dihydroxyacetone kinase
OUO20_19115	COG1461	Dihydroxyacetone kinase
OUO20_19120	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
OUO20_19150	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
OUO20_19165	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
OUO20_19180	COG4948	Mandelate Racemase Muconate Lactonizing
OUO20_19190	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OUO20_19195	COG0583	DNA-binding transcription factor activity
OUO20_19215	COG0589	response to stress
OUO20_19230	COG0784	Response regulator, receiver
OUO20_19230	COG2205	protein histidine kinase activity
OUO20_19230	COG5002	protein histidine kinase activity
OUO20_19265	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
OUO20_19280	COG0306	phosphate transporter
OUO20_19315	COG1609	Transcriptional regulator
OUO20_19330	COG1595	DNA-templated transcription, initiation
OUO20_19355	COG1609	Transcriptional regulator
OUO20_19360	COG1335	isochorismatase
OUO20_19365	COG0831	urea catabolic process
OUO20_19370	COG0832	Belongs to the urease beta subunit family
OUO20_19375	COG0804	urea catabolic process
OUO20_19380	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
OUO20_19385	COG0830	nickel cation binding
OUO20_19390	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
OUO20_19395	COG0829	nickel cation binding
OUO20_19400	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
OUO20_19445	COG3958	Transketolase
OUO20_19450	COG3959	Transketolase, thiamine diphosphate binding domain
OUO20_19455	COG0477	Major facilitator Superfamily
OUO20_19465	COG1028	Short-chain dehydrogenase reductase Sdr
OUO20_19470	COG2376	Dihydroxyacetone kinase
OUO20_19475	COG0698	ribose 5-phosphate isomerase
OUO20_19490	COG0402	S-adenosylhomocysteine deaminase activity
OUO20_19540	COG2723	6-phospho-beta-galactosidase activity
OUO20_19565	COG1234	tRNA 3'-trailer cleavage
OUO20_19570	COG3250	beta-galactosidase activity
OUO20_19585	COG3507	Belongs to the glycosyl hydrolase 43 family
OUO20_19595	COG1414	Transcriptional regulator
OUO20_19605	COG3250	beta-galactosidase activity
OUO20_19610	COG0657	acetylesterase activity
OUO20_19635	COG1175	transmembrane transport
OUO20_19640	COG0395	ABC-type sugar transport system, permease component
OUO20_19645	COG4948	Mandelate Racemase Muconate Lactonizing
OUO20_19660	COG4948	Mandelate Racemase Muconate Lactonizing
OUO20_19670	COG0477	Major facilitator Superfamily
OUO20_19675	COG0477	Major facilitator Superfamily
OUO20_19695	COG2226	methyltransferase
OUO20_19700	COG2826	transposase and inactivated derivatives, IS30 family
OUO20_19710	COG2226	methyltransferase
OUO20_19725	COG1028	Short-chain dehydrogenase reductase Sdr
OUO20_19735	COG1960	acyl-CoA dehydrogenase activity
OUO20_19755	COG0385	Bile acid
OUO20_19760	COG0243	molybdopterin cofactor binding
OUO20_19775	COG0657	acetylesterase activity
OUO20_19780	COG0179	Fumarylacetoacetate (FAA) hydrolase
OUO20_19785	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OUO20_19805	COG1028	Short-chain dehydrogenase reductase Sdr
OUO20_19820	COG0436	Aminotransferase
OUO20_19825	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
OUO20_19835	COG0583	DNA-binding transcription factor activity
OUO20_19840	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
OUO20_19855	COG1984	allophanate hydrolase subunit 2
OUO20_19860	COG4221	oxidoreductase activity
OUO20_19865	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
OUO20_19870	COG1028	Short-chain dehydrogenase reductase Sdr
OUO20_19875	COG1063	alcohol dehydrogenase
OUO20_19880	COG3265	gluconokinase activity
OUO20_19890	COG0697	spore germination
OUO20_19900	COG0667	Aldo Keto reductase
OUO20_19945	COG0656	L-ascorbic acid biosynthetic process
OUO20_19955	COG0183	Belongs to the thiolase family
OUO20_19965	COG1309	transcriptional regulator
OUO20_19975	COG0667	Aldo Keto reductase
OUO20_19980	COG0656	L-ascorbic acid biosynthetic process
OUO20_19995	COG3360	Dodecin
OUO20_20000	COG2186	Transcriptional regulator
OUO20_20010	COG2084	Dehydrogenase
OUO20_20045	COG0300	oxidoreductase activity
OUO20_20055	COG0477	Major facilitator Superfamily
OUO20_20065	COG3285	dna ligase
OUO20_20065	COG1793	dna ligase
OUO20_20075	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
OUO20_20095	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OUO20_20095	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OUO20_20095	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
OUO20_20100	COG1105	Belongs to the carbohydrate kinase PfkB family
OUO20_20105	COG1349	DNA-binding transcription factor activity
OUO20_20120	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OUO20_20130	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
OUO20_20140	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
OUO20_20145	COG0509	glycine decarboxylation via glycine cleavage system
OUO20_20150	COG0404	The glycine cleavage system catalyzes the degradation of glycine
OUO20_20155	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
OUO20_20155	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
OUO20_20160	COG1113	amino acid transport
OUO20_20170	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
OUO20_20175	COG2733	membrane
OUO20_20185	COG1804	L-carnitine dehydratase bile acid-inducible protein F
OUO20_20230	COG4122	O-methyltransferase activity
OUO20_20280	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OUO20_20285	COG1191	sigma factor activity
OUO20_20290	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
OUO20_20305	COG0297	glycogen (starch) synthase activity
OUO20_20310	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
OUO20_20330	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
OUO20_20330	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
OUO20_20340	COG0583	DNA-binding transcription factor activity
OUO20_20350	COG1028	Short-chain dehydrogenase reductase Sdr
OUO20_20360	COG1733	regulation of RNA biosynthetic process
OUO20_20365	COG0702	epimerase
OUO20_20370	COG1280	lysine exporter protein (LysE YggA)
OUO20_20385	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
OUO20_20405	COG0179	Fumarylacetoacetate (FAA) hydrolase
OUO20_20410	COG0589	response to stress
OUO20_20430	COG3290	protein histidine kinase activity
OUO20_20435	COG4565	transcriptional regulatory protein
OUO20_20445	COG3263	regulation of cellular component size
OUO20_20450	COG2252	PERMEase
OUO20_20490	COG0791	NLP P60 protein
OUO20_20490	COG3883	PFAM NLP P60 protein
OUO20_20510	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
OUO20_20510	COG1796	DNA polymerase
OUO20_20585	COG1609	Transcriptional regulator
OUO20_20600	COG1024	Enoyl-CoA hydratase
OUO20_20620	COG0789	Transcriptional regulator
OUO20_20630	COG1278	Cold shock
OUO20_20640	COG4585	Histidine kinase
OUO20_20650	COG0183	Belongs to the thiolase family
OUO20_20660	COG2031	fatty acid transporter
OUO20_20665	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OUO20_20675	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
OUO20_20685	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
OUO20_20715	COG0191	fructose-bisphosphate aldolase activity
OUO20_20765	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
OUO20_20785	COG1832	CoA-binding protein
OUO20_20795	COG2315	Protein conserved in bacteria
OUO20_20815	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OUO20_20820	COG0047	phosphoribosylformylglycinamidine synthase activity
OUO20_20835	COG1404	Belongs to the peptidase S8 family
OUO20_20855	COG1846	Transcriptional regulator
OUO20_20880	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
OUO20_20920	COG0386	Belongs to the glutathione peroxidase family
OUO20_20925	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
OUO20_20950	COG1309	transcriptional regulator
OUO20_20960	COG0438	transferase activity, transferring glycosyl groups
OUO20_20985	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
OUO20_21015	COG0745	RESPONSE REGULATOR receiver
OUO20_21025	COG0028	Belongs to the TPP enzyme family
OUO20_21030	COG0351	phosphomethylpyrimidine kinase
OUO20_21065	COG0343	queuine tRNA-ribosyltransferase activity
OUO20_21095	COG1621	beta-fructofuranosidase activity
OUO20_21110	COG1960	acyl-CoA dehydrogenase activity
OUO20_21140	COG0586	Pfam SNARE associated Golgi protein
OUO20_21150	COG0564	pseudouridine synthase activity
OUO20_21170	COG2364	Membrane
OUO20_21175	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
OUO20_21185	COG0723	plastoquinol--plastocyanin reductase activity
OUO20_21215	COG0028	Belongs to the TPP enzyme family
OUO20_21225	COG2066	Belongs to the glutaminase family
OUO20_21240	COG0179	Fumarylacetoacetate (FAA) hydrolase
OUO20_21260	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OUO20_21265	COG1609	Transcriptional regulator
OUO20_21275	COG1175	transmembrane transport
OUO20_21280	COG0395	ABC-type sugar transport system, permease component
OUO20_21290	COG0673	inositol 2-dehydrogenase activity
OUO20_21305	COG0246	Mannitol dehydrogenase
OUO20_21315	COG4948	Mandelate Racemase Muconate Lactonizing
OUO20_21335	COG1063	alcohol dehydrogenase
OUO20_21390	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
OUO20_21405	COG0745	RESPONSE REGULATOR receiver