locus-tag	class	description
NG819_00135	COG0577	efflux transmembrane transporter activity
NG819_00135	COG1136	(ABC) transporter
NG819_00245	COG2062	phosphohistidine phosphatase, SixA
NG819_00260	COG0745	RESPONSE REGULATOR receiver
NG819_00280	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NG819_00290	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NG819_00310	COG0671	phosphoesterase, PA-phosphatase related
NG819_00320	COG0438	transferase activity, transferring glycosyl groups
NG819_00345	COG1063	alcohol dehydrogenase
NG819_00390	COG0673	inositol 2-dehydrogenase activity
NG819_00400	COG0395	ABC-type sugar transport system, permease component
NG819_00405	COG1175	transmembrane transport
NG819_00435	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NG819_00460	COG0179	Fumarylacetoacetate (FAA) hydrolase
NG819_00520	COG2364	Membrane
NG819_00545	COG0586	Pfam SNARE associated Golgi protein
NG819_00605	COG0343	queuine tRNA-ribosyltransferase activity
NG819_00635	COG0477	Major facilitator Superfamily
NG819_00695	COG0438	transferase activity, transferring glycosyl groups
NG819_00705	COG1309	transcriptional regulator
NG819_00730	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
NG819_00735	COG0386	Belongs to the glutathione peroxidase family
NG819_00745	COG1196	nuclear chromosome segregation
NG819_00745	COG0741	lytic transglycosylase activity
NG819_00745	COG0739	heme binding
NG819_00795	COG1846	Transcriptional regulator
NG819_00815	COG1404	Belongs to the peptidase S8 family
NG819_00835	COG0047	phosphoribosylformylglycinamidine synthase activity
NG819_00875	COG1832	CoA-binding protein
NG819_00895	COG1832	CoA-binding protein
NG819_00915	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NG819_00970	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NG819_00995	COG2031	fatty acid transporter
NG819_01010	COG1278	Cold shock
NG819_01020	COG0789	Transcriptional regulator
NG819_01035	COG1024	Enoyl-CoA hydratase
NG819_01185	COG2252	PERMEase
NG819_01190	COG3263	regulation of cellular component size
NG819_01195	COG0010	Belongs to the arginase family
NG819_01220	COG0589	response to stress
NG819_01270	COG1733	regulation of RNA biosynthetic process
NG819_01280	COG1028	Short-chain dehydrogenase reductase Sdr
NG819_01310	COG1028	Short-chain dehydrogenase reductase Sdr
NG819_01325	COG0438	transferase activity, transferring glycosyl groups
NG819_01335	COG0859	PFAM glycosyl transferase family 9
NG819_01340	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
NG819_01455	COG2733	membrane
NG819_01490	COG1113	amino acid transport
NG819_01500	COG0404	The glycine cleavage system catalyzes the degradation of glycine
NG819_01505	COG0509	glycine decarboxylation via glycine cleavage system
NG819_01510	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NG819_01520	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NG819_01530	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NG819_01575	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
NG819_01580	COG3285	dna ligase
NG819_01580	COG1793	dna ligase
NG819_01585	COG0477	Major facilitator Superfamily
NG819_01595	COG0300	oxidoreductase activity
NG819_01635	COG2084	Dehydrogenase
NG819_01650	COG3360	Dodecin
NG819_01680	COG1309	transcriptional regulator
NG819_01715	COG2261	transglycosylase associated protein
NG819_01730	COG2890	protein-(glutamine-N5) methyltransferase activity
NG819_01750	COG0667	Aldo Keto reductase
NG819_01770	COG0697	spore germination
NG819_01810	COG0385	Bile acid
NG819_01820	COG0477	Major facilitator Superfamily
NG819_01830	COG1960	acyl-CoA dehydrogenase activity
NG819_01840	COG1028	Short-chain dehydrogenase reductase Sdr
NG819_01850	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NG819_01860	COG0800	Aldolase
NG819_01870	COG0395	ABC-type sugar transport system, permease component
NG819_01875	COG1175	transmembrane transport
NG819_01895	COG1802	Transcriptional regulator
NG819_01925	COG1116	anion transmembrane transporter activity
NG819_01955	COG1028	Short-chain dehydrogenase reductase Sdr
NG819_02000	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
NG819_02005	COG0830	nickel cation binding
NG819_02010	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
NG819_02015	COG0804	urea catabolic process
NG819_02020	COG0832	Belongs to the urease beta subunit family
NG819_02025	COG0831	urea catabolic process
NG819_02085	COG0306	phosphate transporter
NG819_02100	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NG819_02115	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
NG819_02195	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
NG819_02215	COG1506	peptidase
NG819_02215	COG0823	Involved in the tonB-independent uptake of proteins
NG819_02265	COG2814	Major facilitator Superfamily
NG819_02270	COG0693	protein deglycase activity
NG819_02290	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NG819_02320	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NG819_02330	COG0302	gtp cyclohydrolase
NG819_02335	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NG819_02380	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
NG819_02400	COG0561	phosphatase activity
NG819_02410	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NG819_02430	COG0425	Belongs to the sulfur carrier protein TusA family
NG819_02430	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NG819_02435	COG0154	amidase activity
NG819_02450	COG5416	Lipopolysaccharide assembly protein A domain
NG819_02460	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NG819_02470	COG2186	Transcriptional regulator
NG819_02505	COG0778	Nitroreductase
NG819_02510	COG2233	PERMEase
NG819_02560	COG0395	ABC-type sugar transport system, permease component
NG819_02570	COG0673	inositol 2-dehydrogenase activity
NG819_02575	COG0673	inositol 2-dehydrogenase activity
NG819_02595	COG1028	Short-chain dehydrogenase reductase Sdr
NG819_02610	COG1929	Belongs to the glycerate kinase type-1 family
NG819_02615	COG1028	Short-chain dehydrogenase reductase Sdr
NG819_02640	COG5002	protein histidine kinase activity
NG819_02650	COG2200	EAL domain
NG819_02650	COG2203	Gaf domain
NG819_02650	COG2199	diguanylate cyclase activity
NG819_02675	COG0561	phosphatase activity
NG819_02740	COG1175	transmembrane transport
NG819_02750	COG3842	ATPase activity
NG819_02755	COG3842	ATPase activity
NG819_02760	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
NG819_02765	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
NG819_02770	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
NG819_02775	COG1940	carbohydrate kinase activity
NG819_02775	COG1846	Transcriptional regulator
NG819_02785	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NG819_02790	COG0477	Major facilitator Superfamily
NG819_02795	COG1957	nucleoside hydrolase
NG819_02865	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NG819_02875	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
NG819_02885	COG3639	organic phosphonate transmembrane transporter activity
NG819_02910	COG0395	ABC-type sugar transport system, permease component
NG819_02990	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NG819_03040	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NG819_03090	COG0659	secondary active sulfate transmembrane transporter activity
NG819_03100	COG0673	inositol 2-dehydrogenase activity
NG819_03115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NG819_03120	COG1609	Transcriptional regulator
NG819_03125	COG4948	Mandelate Racemase Muconate Lactonizing
NG819_03145	COG1175	transmembrane transport
NG819_03155	COG0673	inositol 2-dehydrogenase activity
NG819_03190	COG1162	GTPase activity
NG819_03200	COG2957	Belongs to the agmatine deiminase family
NG819_03210	COG0277	FAD linked oxidase domain protein
NG819_03265	COG0346	lactoylglutathione lyase activity
NG819_03300	COG2188	Transcriptional regulator
NG819_03310	COG1716	ATPase activity
NG819_03315	COG1716	ATPase activity
NG819_03330	COG0768	penicillin binding
NG819_03350	COG3764	Sortase (surface protein transpeptidase)
NG819_03360	COG2818	Glycosylase
NG819_03385	COG1215	transferase activity, transferring glycosyl groups
NG819_03410	COG3266	domain, Protein
NG819_03420	COG0187	DNA topoisomerase II activity
NG819_03425	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
NG819_03430	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NG819_03435	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
NG819_03440	COG0592	DNA-directed DNA polymerase activity
NG819_03450	COG0230	Belongs to the bacterial ribosomal protein bL34 family
NG819_03455	COG0594	ribonuclease P activity
NG819_03460	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
NG819_03480	COG1192	Involved in chromosome partitioning
NG819_03490	COG3118	belongs to the thioredoxin family
NG819_03495	COG0492	ferredoxin-NADP+ reductase activity
NG819_03520	COG0406	alpha-ribazole phosphatase activity
NG819_03580	COG1113	amino acid transport
NG819_03595	COG2197	response regulator
NG819_03625	COG1216	Glycosyl transferase, family 2
NG819_03640	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NG819_03655	COG2244	polysaccharide biosynthetic process
NG819_03675	COG0360	Binds together with S18 to 16S ribosomal RNA
NG819_03685	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NG819_03690	COG0359	binds to the 23S rRNA
NG819_03730	COG2259	Doxx family
NG819_03780	COG1937	Protein conserved in bacteria
NG819_03820	COG0436	Aminotransferase
NG819_03870	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NG819_03880	COG0183	Belongs to the thiolase family
NG819_03890	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NG819_03910	COG0577	efflux transmembrane transporter activity
NG819_03910	COG1136	(ABC) transporter
NG819_03915	COG1136	(ABC) transporter
NG819_03915	COG0577	efflux transmembrane transporter activity
NG819_03920	COG0477	Major facilitator Superfamily
NG819_03930	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NG819_03935	COG1414	Transcriptional regulator
NG819_03955	COG1597	lipid kinase activity
NG819_03965	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NG819_03970	COG0804	urea catabolic process
NG819_03980	COG1802	Transcriptional regulator
NG819_03985	COG2271	Major facilitator Superfamily
NG819_04025	COG3842	ATPase activity
NG819_04030	COG1840	ABC-type Fe3 transport system, periplasmic component
NG819_04035	COG1607	acyl-coa hydrolase
NG819_04050	COG0515	serine threonine protein kinase
NG819_04050	COG2815	serine threonine protein kinase
NG819_04085	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NG819_04130	COG0431	NADPH-dependent FMN reductase
NG819_04160	COG0673	inositol 2-dehydrogenase activity
NG819_04165	COG0686	Belongs to the AlaDH PNT family
NG819_04185	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NG819_04200	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
NG819_04225	COG0477	Major facilitator Superfamily
NG819_04245	COG1309	transcriptional regulator
NG819_04265	COG1280	lysine exporter protein (LysE YggA)
NG819_04270	COG1522	sequence-specific DNA binding
NG819_04285	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NG819_04325	COG2186	Transcriptional regulator
NG819_04330	COG0586	Pfam SNARE associated Golgi protein
NG819_04375	COG3012	SEC-C Motif Domain Protein
NG819_04455	COG0227	Belongs to the bacterial ribosomal protein bL28 family
NG819_04460	COG0267	Belongs to the bacterial ribosomal protein bL33 family
NG819_04465	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NG819_04485	COG1609	Transcriptional regulator
NG819_04525	COG0776	regulation of translation
NG819_04585	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NG819_04590	COG1301	dicarboxylic acid transport
NG819_04605	COG0583	DNA-binding transcription factor activity
NG819_04610	COG1840	ABC-type Fe3 transport system, periplasmic component
NG819_04630	COG3842	ATPase activity
NG819_04635	COG2828	Protein conserved in bacteria
NG819_04660	COG1846	Transcriptional regulator
NG819_04660	COG1940	carbohydrate kinase activity
NG819_04670	COG1175	transmembrane transport
NG819_04675	COG0395	ABC-type sugar transport system, permease component
NG819_04680	COG3842	ATPase activity
NG819_04705	COG0383	alpha-mannosidase activity
NG819_04710	COG1082	Xylose isomerase domain protein TIM barrel
NG819_04715	COG0726	polysaccharide deacetylase
NG819_04755	COG3246	L-lysine catabolic process to acetate
NG819_04760	COG1028	Short-chain dehydrogenase reductase Sdr
NG819_04765	COG1609	Transcriptional regulator
NG819_04770	COG2267	carboxylic ester hydrolase activity
NG819_04835	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NG819_04845	COG0667	Aldo Keto reductase
NG819_04860	COG2814	Major facilitator Superfamily
NG819_04900	COG0583	DNA-binding transcription factor activity
NG819_04930	COG0717	Belongs to the dCTP deaminase family
NG819_04935	COG0475	glutathione-regulated potassium exporter activity
NG819_04940	COG0569	domain protein
NG819_04940	COG2985	domain, Protein
NG819_04955	COG1006	Multisubunit Na H antiporter MnhC subunit
NG819_04960	COG0651	ATP synthesis coupled electron transport
NG819_04970	COG2212	antiporter activity
NG819_04975	COG1320	monovalent cation:proton antiporter activity
NG819_05000	COG4721	ABC-type cobalt transport system, permease component
NG819_05005	COG1122	ATPase activity
NG819_05020	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
NG819_05025	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
NG819_05075	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NG819_05090	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NG819_05095	COG1280	lysine exporter protein (LysE YggA)
NG819_05135	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NG819_05220	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NG819_05365	COG0220	tRNA (guanine-N7-)-methyltransferase activity
NG819_05375	COG2807	transmembrane transport
NG819_05430	COG0135	phosphoribosylanthranilate isomerase activity
NG819_05435	COG3304	Inner membrane component domain
NG819_05460	COG3585	molybdate ion transport
NG819_05560	COG2814	Major facilitator Superfamily
NG819_05565	COG2271	Major facilitator Superfamily
NG819_05570	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NG819_05600	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
NG819_05630	COG4176	ABC-type proline glycine betaine transport system permease component
NG819_05635	COG4176	ABC-type proline glycine betaine transport system permease component
NG819_05640	COG0517	IMP dehydrogenase activity
NG819_05640	COG4175	Glycine betaine
NG819_05650	COG2351	hydroxyisourate hydrolase activity
NG819_05670	COG1366	Belongs to the anti-sigma-factor antagonist family
NG819_05680	COG0745	RESPONSE REGULATOR receiver
NG819_05720	COG2084	Dehydrogenase
NG819_05735	COG0477	Major facilitator Superfamily
NG819_05785	COG1301	dicarboxylic acid transport
NG819_05795	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NG819_05815	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NG819_05830	COG0726	polysaccharide deacetylase
NG819_05850	COG1136	(ABC) transporter
NG819_05850	COG0577	efflux transmembrane transporter activity
NG819_05875	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NG819_05880	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NG819_05890	COG2329	Antibiotic biosynthesis monooxygenase
NG819_05895	COG4251	negative regulation of phosphorylation
NG819_05950	COG2271	Major facilitator Superfamily
NG819_05955	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NG819_05960	COG1609	Transcriptional regulator
NG819_05995	COG0640	Transcriptional regulator
NG819_06040	COG0477	Major facilitator Superfamily
NG819_06050	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NG819_06070	COG1012	belongs to the aldehyde dehydrogenase family
NG819_06080	COG0477	Major facilitator Superfamily
NG819_06135	COG0129	dihydroxy-acid dehydratase activity
NG819_06165	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NG819_06195	COG1063	alcohol dehydrogenase
NG819_06200	COG1064	alcohol dehydrogenase
NG819_06305	COG0579	oxidoreductase
NG819_06335	COG0640	Transcriptional regulator
NG819_06345	COG0745	RESPONSE REGULATOR receiver
NG819_06355	COG0563	adenylate kinase activity
NG819_06360	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NG819_06380	COG0484	heat shock protein binding
NG819_06415	COG0546	phosphoglycolate phosphatase activity
NG819_06425	COG3257	ureidoglycine aminohydrolase activity
NG819_06450	COG2233	PERMEase
NG819_06485	COG2252	PERMEase
NG819_06585	COG1132	(ABC) transporter
NG819_06590	COG1132	(ABC) transporter
NG819_06620	COG1609	Transcriptional regulator
NG819_06630	COG1175	transmembrane transport
NG819_06635	COG0395	ABC-type sugar transport system, permease component
NG819_06655	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
NG819_06670	COG0395	ABC-type sugar transport system, permease component
NG819_06685	COG1609	Transcriptional regulator
NG819_06695	COG0395	ABC-type sugar transport system, permease component
NG819_06700	COG0395	ABC-type sugar transport system, permease component
NG819_06715	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NG819_06830	COG0569	domain protein
NG819_06840	COG0123	including yeast histone deacetylase and acetoin utilization protein
NG819_06845	COG0640	Transcriptional regulator
NG819_06905	COG1175	transmembrane transport
NG819_06940	COG5578	integral membrane protein
NG819_06945	COG1653	transport
NG819_06950	COG1653	transport
NG819_06955	COG4209	transmembrane transport
NG819_06960	COG0395	ABC-type sugar transport system, permease component
NG819_06985	COG1609	Transcriptional regulator
NG819_07005	COG1070	Carbohydrate kinase
NG819_07010	COG3458	cephalosporin-C deacetylase activity
NG819_07040	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NG819_07055	COG0406	alpha-ribazole phosphatase activity
NG819_07060	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NG819_07075	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NG819_07080	COG0443	Heat shock 70 kDa protein
NG819_07140	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NG819_07150	COG1266	CAAX protease self-immunity
NG819_07190	COG1250	3-hydroxyacyl-CoA dehydrogenase
NG819_07220	COG2050	protein possibly involved in aromatic compounds catabolism
NG819_07225	COG1012	belongs to the aldehyde dehydrogenase family
NG819_07225	COG2030	dehydratase
NG819_07250	COG2050	protein possibly involved in aromatic compounds catabolism
NG819_07290	COG0071	Belongs to the small heat shock protein (HSP20) family
NG819_07315	COG1316	TRANSCRIPTIONal
NG819_07320	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NG819_07350	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NG819_07360	COG3842	ATPase activity
NG819_07395	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
NG819_07400	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
NG819_07410	COG0277	FAD linked oxidase domain protein
NG819_07415	COG3511	phospholipase C
NG819_07470	COG0508	dehydrogenase complex catalyzes the overall conversion of
NG819_07485	COG0477	Major facilitator Superfamily
NG819_07515	COG0730	response to heat
NG819_07520	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NG819_07545	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NG819_07550	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NG819_07565	COG2353	YceI-like domain
NG819_07615	COG1247	-acetyltransferase
NG819_07630	COG0640	Transcriptional regulator
NG819_07640	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NG819_07660	COG0300	oxidoreductase activity
NG819_07680	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NG819_07725	COG0642	Histidine kinase
NG819_07740	COG0586	Pfam SNARE associated Golgi protein
NG819_07745	COG0671	phosphoesterase, PA-phosphatase related
NG819_07765	COG3460	Phenylacetate-CoA oxygenase
NG819_07775	COG2151	metal-sulfur cluster biosynthetic enzyme
NG819_07790	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NG819_07830	COG0110	maltose O-acetyltransferase activity
NG819_07835	COG1215	transferase activity, transferring glycosyl groups
NG819_07865	COG0489	protein tyrosine kinase activity
NG819_07960	COG1414	Transcriptional regulator
NG819_07965	COG1414	Transcriptional regulator
NG819_07980	COG2814	Major facilitator Superfamily
NG819_08005	COG2721	sulfolactate sulfo-lyase activity
NG819_08015	COG4124	Belongs to the glycosyl hydrolase 26 family
NG819_08025	COG1595	DNA-templated transcription, initiation
NG819_08045	COG0076	glutamate decarboxylase activity
NG819_08070	COG0784	Response regulator, receiver
NG819_08070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NG819_08070	COG2198	Histidine kinase
NG819_08070	COG2205	protein histidine kinase activity
NG819_08080	COG0745	RESPONSE REGULATOR receiver
NG819_08090	COG1968	undecaprenyl-diphosphatase activity
NG819_08105	COG1063	alcohol dehydrogenase
NG819_08130	COG2239	Acts as a magnesium transporter
NG819_08160	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
NG819_08230	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NG819_08245	COG0438	transferase activity, transferring glycosyl groups
NG819_08265	COG0022	dehydrogenase e1 component
NG819_08295	COG1215	transferase activity, transferring glycosyl groups
NG819_08305	COG2188	Transcriptional regulator
NG819_08315	COG2801	Transposase and inactivated derivatives
NG819_08330	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
NG819_08340	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
NG819_08340	COG2755	lipolytic protein G-D-S-L family
NG819_08360	COG1316	TRANSCRIPTIONal
NG819_08380	COG1846	Transcriptional regulator
NG819_08395	COG0492	ferredoxin-NADP+ reductase activity
NG819_08440	COG1116	anion transmembrane transporter activity
NG819_08445	COG3290	protein histidine kinase activity
NG819_08450	COG4565	transcriptional regulatory protein
NG819_08490	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
NG819_08495	COG1982	Orn Lys Arg decarboxylase major
NG819_08500	COG1982	Orn Lys Arg decarboxylase major
NG819_08515	COG0367	asparagine synthase
NG819_08535	COG3559	Exporter of polyketide antibiotics
NG819_08545	COG0598	Magnesium transport protein CorA
NG819_08550	COG1914	H( )-stimulated, divalent metal cation uptake system
NG819_08555	COG1982	Orn Lys Arg decarboxylase major
NG819_08565	COG4948	Mandelate Racemase Muconate Lactonizing
NG819_08600	COG2226	methyltransferase
NG819_08625	COG2860	membrane
NG819_08665	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
NG819_08705	COG2188	Transcriptional regulator
NG819_08735	COG1012	belongs to the aldehyde dehydrogenase family
NG819_08750	COG1215	transferase activity, transferring glycosyl groups
NG819_08840	COG0501	Belongs to the peptidase M48B family
NG819_08920	COG4948	Mandelate Racemase Muconate Lactonizing
NG819_08925	COG0028	Belongs to the TPP enzyme family
NG819_08930	COG0028	Belongs to the TPP enzyme family
NG819_08960	COG2017	converts alpha-aldose to the beta-anomer
NG819_08965	COG2017	converts alpha-aldose to the beta-anomer
NG819_08970	COG1063	alcohol dehydrogenase
NG819_08985	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NG819_09025	COG0754	glutathionylspermidine amidase activity
NG819_09110	COG0702	epimerase
NG819_09120	COG1940	carbohydrate kinase activity
NG819_09125	COG0366	Alpha amylase catalytic
NG819_09130	COG4989	oxidoreductase activity
NG819_09170	COG0738	Major facilitator superfamily
NG819_09220	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NG819_09250	COG0456	acetyltransferase
NG819_09265	COG3485	protocatechuate 3,4-dioxygenase
NG819_09320	COG2197	response regulator
NG819_09345	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NG819_09350	COG0081	regulation of translation
NG819_09365	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NG819_09375	COG0442	prolyl-tRNA aminoacylation
NG819_09380	COG0183	Belongs to the thiolase family
NG819_09390	COG0085	RNA polymerase activity
NG819_09400	COG0085	RNA polymerase activity
NG819_09410	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NG819_09415	COG0049	tRNA binding
NG819_09445	COG0051	transcription antitermination factor activity, RNA binding
NG819_09450	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NG819_09460	COG0089	rRNA binding
NG819_09465	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NG819_09470	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NG819_09475	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NG819_09485	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NG819_09495	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NG819_09500	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NG819_09505	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NG819_09510	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NG819_09515	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NG819_09520	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NG819_09530	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NG819_09535	COG1841	ribosomal large subunit assembly
NG819_09540	COG0200	Binds to the 23S rRNA
NG819_09550	COG0563	adenylate kinase activity
NG819_09580	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NG819_09585	COG0257	Belongs to the bacterial ribosomal protein bL36 family
NG819_09590	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NG819_09595	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NG819_09600	COG0202	RNA polymerase activity
NG819_09605	COG0203	ribosomal protein L17
NG819_09620	COG0745	RESPONSE REGULATOR receiver
NG819_09730	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NG819_09740	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NG819_09745	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NG819_09750	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NG819_09780	COG1970	mechanosensitive ion channel activity
NG819_09785	COG1876	peptidase activity
NG819_09805	COG0736	holo-[acyl-carrier-protein] synthase activity
NG819_09845	COG2759	Belongs to the formate--tetrahydrofolate ligase family
NG819_09850	COG0438	transferase activity, transferring glycosyl groups
NG819_09855	COG0438	transferase activity, transferring glycosyl groups
NG819_09875	COG0802	atpase or kinase
NG819_09890	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NG819_09900	COG1472	Belongs to the glycosyl hydrolase 3 family
NG819_09905	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NG819_09920	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NG819_09980	COG0516	GMP reductase activity
NG819_09985	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NG819_10030	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NG819_10035	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NG819_10065	COG0598	Magnesium transport protein CorA
NG819_10085	COG2814	Major facilitator Superfamily
NG819_10110	COG1174	glycine betaine transport
NG819_10130	COG2326	polyphosphate kinase activity
NG819_10135	COG1722	exodeoxyribonuclease VII activity
NG819_10140	COG1570	exodeoxyribonuclease VII activity
NG819_10150	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NG819_10170	COG3046	protein related to deoxyribodipyrimidine photolyase
NG819_10180	COG4166	transmembrane transport
NG819_10190	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NG819_10235	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NG819_10240	COG3226	Transcriptional regulator
NG819_10285	COG1126	abc transporter atp-binding protein
NG819_10315	COG1595	DNA-templated transcription, initiation
NG819_10330	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NG819_10360	COG0613	PHP domain protein
NG819_10365	COG2189	Belongs to the N(4) N(6)-methyltransferase family
NG819_10375	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
NG819_10380	COG0352	thiamine-phosphate diphosphorylase activity
NG819_10385	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NG819_10430	COG1231	oxidoreductase activity
NG819_10440	COG3253	May function as heme-dependent peroxidase
NG819_10445	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
NG819_10450	COG0181	hydroxymethylbilane synthase activity
NG819_10460	COG0113	porphobilinogen synthase activity
NG819_10470	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
NG819_10480	COG0765	amino acid transport
NG819_10485	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NG819_10515	COG2816	NAD+ diphosphatase activity
NG819_10565	COG1842	Phage shock protein A
NG819_10590	COG2086	electron transfer activity
NG819_10615	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
NG819_10620	COG0484	heat shock protein binding
NG819_10645	COG0482	sulfurtransferase activity
NG819_10655	COG0601	transmembrane transport
NG819_10690	COG0714	Associated with various cellular activities
NG819_10735	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NG819_10745	COG0653	protein targeting
NG819_10750	COG0653	protein targeting
NG819_10755	COG0653	protein targeting
NG819_10910	COG1216	Glycosyl transferase, family 2
NG819_10920	COG1088	dTDP-glucose 4,6-dehydratase activity
NG819_10925	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NG819_10980	COG2884	Cell division ATP-binding protein ftsE
NG819_10995	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NG819_11010	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NG819_11045	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NG819_11070	COG0483	inositol monophosphate 1-phosphatase activity
NG819_11080	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
NG819_11090	COG1595	DNA-templated transcription, initiation
NG819_11155	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NG819_11165	COG1064	alcohol dehydrogenase
NG819_11170	COG0537	adenosine 5'-monophosphoramidase activity
NG819_11210	COG0460	homoserine dehydrogenase
NG819_11215	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NG819_11220	COG0083	homoserine kinase activity
NG819_11270	COG0356	it plays a direct role in the translocation of protons across the membrane
NG819_11275	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NG819_11280	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NG819_11285	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NG819_11300	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NG819_11305	COG0355	proton-transporting ATP synthase activity, rotational mechanism
NG819_11315	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
NG819_11330	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
NG819_11385	COG0363	glucosamine-6-phosphate deaminase activity
NG819_11400	COG1335	isochorismatase
NG819_11410	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
NG819_11420	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
NG819_11425	COG1234	tRNA 3'-trailer cleavage
NG819_11440	COG0586	Pfam SNARE associated Golgi protein
NG819_11505	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NG819_11520	COG1104	cysteine desulfurase activity
NG819_11540	COG1305	Transglutaminase-like
NG819_11555	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NG819_11600	COG0088	Forms part of the polypeptide exit tunnel
NG819_11605	COG0129	dihydroxy-acid dehydratase activity
NG819_11615	COG0440	acetolactate synthase activity
NG819_11620	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NG819_11635	COG1136	(ABC) transporter
NG819_11635	COG0577	efflux transmembrane transporter activity
NG819_11640	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NG819_11660	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NG819_11730	COG0066	3-isopropylmalate dehydratase activity
NG819_11735	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NG819_11745	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
NG819_11750	COG1181	Belongs to the D-alanine--D-alanine ligase family
NG819_11765	COG1461	Dihydroxyacetone kinase
NG819_11790	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NG819_11800	COG0333	Belongs to the bacterial ribosomal protein bL32 family
NG819_11805	COG0571	ribonuclease III activity
NG819_11810	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
NG819_11815	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NG819_11825	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NG819_11855	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NG819_11870	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NG819_11880	COG2514	catechol 2,3-dioxygenase activity
NG819_11890	COG0228	four-way junction DNA binding
NG819_11895	COG1837	Belongs to the UPF0109 family
NG819_11900	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NG819_11910	COG0335	large ribosomal subunit rRNA binding
NG819_11915	COG0681	Belongs to the peptidase S26 family
NG819_11925	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NG819_11935	COG0792	nuclease activity
NG819_11950	COG4974	Belongs to the 'phage' integrase family
NG819_11965	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NG819_11970	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NG819_12020	COG1028	Short-chain dehydrogenase reductase Sdr
NG819_12025	COG1063	alcohol dehydrogenase
NG819_12050	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NG819_12055	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NG819_12095	COG0242	peptide deformylase activity
NG819_12105	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
NG819_12120	COG2017	converts alpha-aldose to the beta-anomer
NG819_12130	COG1609	Transcriptional regulator
NG819_12185	COG0464	growth
NG819_12190	COG1946	Acyl-CoA thioesterase
NG819_12205	COG0668	transmembrane transport
NG819_12250	COG0740	serine-type endopeptidase activity
NG819_12255	COG0740	serine-type endopeptidase activity
NG819_12260	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NG819_12265	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
NG819_12295	COG0285	dihydrofolate synthase activity
NG819_12305	COG0105	UTP biosynthetic process
NG819_12340	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NG819_12355	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NG819_12365	COG0799	negative regulation of ribosome biogenesis
NG819_12395	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
NG819_12475	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
NG819_12490	COG0583	DNA-binding transcription factor activity
NG819_12525	COG1780	Probably involved in ribonucleotide reductase function
NG819_12535	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NG819_12765	COG1028	Short-chain dehydrogenase reductase Sdr
NG819_12840	COG0587	DNA-directed DNA polymerase activity
NG819_12855	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NG819_12870	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NG819_12885	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NG819_12890	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
NG819_12895	COG0217	transcriptional regulatory protein
NG819_12900	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
NG819_12905	COG0632	four-way junction helicase activity
NG819_13015	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NG819_13020	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NG819_13025	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NG819_13035	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NG819_13040	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NG819_13050	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NG819_13055	COG0540	Belongs to the ATCase OTCase family
NG819_13070	COG0505	Belongs to the CarA family
NG819_13080	COG0284	orotidine-5'-phosphate decarboxylase activity
NG819_13095	COG1758	RNA polymerase activity
NG819_13105	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NG819_13115	COG0438	transferase activity, transferring glycosyl groups
NG819_13140	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NG819_13150	COG0723	plastoquinol--plastocyanin reductase activity
NG819_13160	COG1307	EDD domain protein, DegV family
NG819_13175	COG1555	photosystem II stabilization
NG819_13195	COG0268	Binds directly to 16S ribosomal RNA
NG819_13230	COG0484	heat shock protein binding
NG819_13260	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NG819_13275	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NG819_13280	COG1381	Involved in DNA repair and RecF pathway recombination
NG819_13315	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NG819_13320	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NG819_13345	COG0723	plastoquinol--plastocyanin reductase activity
NG819_13350	COG2010	Cytochrome c
NG819_13355	COG1845	cytochrome c oxidase, subunit III
NG819_13360	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NG819_13425	COG1216	Glycosyl transferase, family 2
NG819_13440	COG0805	protein transport
NG819_13445	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NG819_13465	COG0545	Peptidyl-prolyl cis-trans isomerase
NG819_13470	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
NG819_13475	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
NG819_13480	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
NG819_13505	COG0517	IMP dehydrogenase activity
NG819_13505	COG1994	Peptidase M50
NG819_13520	COG0215	cysteine-tRNA ligase activity
NG819_13525	COG1968	undecaprenyl-diphosphatase activity
NG819_13640	COG0435	Glutathione S-transferase
NG819_13660	COG1028	Short-chain dehydrogenase reductase Sdr
NG819_13700	COG1305	Transglutaminase-like
NG819_13715	COG2855	membrane
NG819_13730	COG0254	rRNA binding
NG819_13750	COG0560	Phosphoserine phosphatase
NG819_13750	COG3830	Belongs to the UPF0237 family
NG819_13755	COG1028	Short-chain dehydrogenase reductase Sdr
NG819_13760	COG1028	Short-chain dehydrogenase reductase Sdr
NG819_13785	COG0488	(ABC) transporter
NG819_13795	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
NG819_13810	COG0346	lactoylglutathione lyase activity
NG819_13820	COG1309	transcriptional regulator
NG819_13830	COG1268	BioY protein
NG819_13845	COG0183	Belongs to the thiolase family
NG819_13865	COG2151	metal-sulfur cluster biosynthetic enzyme
NG819_13870	COG0396	ATPase activity
NG819_13905	COG1612	heme a metabolic process
NG819_13915	COG0109	protoheme IX farnesyltransferase activity
NG819_13930	COG0166	Belongs to the GPI family
NG819_13955	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NG819_13960	COG0149	triose-phosphate isomerase activity
NG819_13970	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NG819_13985	COG0391	Required for morphogenesis under gluconeogenic growth conditions
NG819_14000	COG0318	PFAM AMP-dependent synthetase and ligase
NG819_14000	COG0204	Acyl-transferase
NG819_14030	COG4106	trans-aconitate 2-methyltransferase activity
NG819_14055	COG1653	transport
NG819_14065	COG0237	dephospho-CoA kinase activity
NG819_14065	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NG819_14075	COG1739	Uncharacterized protein family UPF0029
NG819_14085	COG0539	negative regulation of cytoplasmic translation
NG819_14090	COG4552	Acetyltransferase involved in intracellular survival and related
NG819_14100	COG2050	protein possibly involved in aromatic compounds catabolism
NG819_14170	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NG819_14180	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NG819_14200	COG0406	alpha-ribazole phosphatase activity
NG819_14245	COG1028	Short-chain dehydrogenase reductase Sdr
NG819_14255	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NG819_14260	COG0477	Major facilitator Superfamily
NG819_14270	COG2268	Band 7 protein
NG819_14295	COG2124	cytochrome p450
NG819_14335	COG0709	Synthesizes selenophosphate from selenide and ATP
NG819_14345	COG0437	4 iron, 4 sulfur cluster binding
NG819_14405	COG2340	Cysteine-rich secretory protein family
NG819_14430	COG2814	Major facilitator Superfamily
NG819_14450	COG2197	response regulator
NG819_14480	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
NG819_14485	COG4638	Rieske (2fe-2S)
NG819_14490	COG3485	protocatechuate 3,4-dioxygenase
NG819_14505	COG1609	Transcriptional regulator
NG819_14515	COG1175	transmembrane transport
NG819_14520	COG0395	ABC-type sugar transport system, permease component
NG819_14550	COG1268	BioY protein
NG819_14645	COG1177	transmembrane transport
NG819_14650	COG3842	ATPase activity
NG819_14655	COG0483	inositol monophosphate 1-phosphatase activity
NG819_14665	COG1620	l-lactate permease
NG819_14670	COG0277	FAD linked oxidase domain protein
NG819_14690	COG0667	Aldo Keto reductase
NG819_14695	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NG819_14710	COG0667	Aldo Keto reductase
NG819_14735	COG2801	Transposase and inactivated derivatives
NG819_14755	COG1621	beta-fructofuranosidase activity
NG819_14760	COG1609	Transcriptional regulator
NG819_14765	COG0395	ABC-type sugar transport system, permease component
NG819_14935	COG0596	Alpha beta hydrolase
NG819_14940	COG2197	response regulator
NG819_14955	COG1028	Short-chain dehydrogenase reductase Sdr
NG819_14975	COG0252	asparaginase activity
NG819_14985	COG3835	regulator
NG819_15005	COG0439	Biotin carboxylase
NG819_15010	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
NG819_15020	COG1984	allophanate hydrolase subunit 2
NG819_15030	COG2801	Transposase and inactivated derivatives
NG819_15070	COG1250	3-hydroxyacyl-CoA dehydrogenase
NG819_15175	COG1316	TRANSCRIPTIONal
NG819_15195	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
NG819_15270	COG2807	transmembrane transport
NG819_15335	COG1113	amino acid transport
NG819_15355	COG1414	Transcriptional regulator
NG819_15370	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NG819_15380	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NG819_15385	COG0280	phosphate acetyltransferase
NG819_15400	COG0583	DNA-binding transcription factor activity
NG819_15405	COG1012	belongs to the aldehyde dehydrogenase family
NG819_15430	COG0251	oxidation-reduction process
NG819_15435	COG2271	Major facilitator Superfamily
NG819_15515	COG3328	transposase activity
NG819_15525	COG0789	Transcriptional regulator
NG819_15535	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NG819_15570	COG0701	Predicted permease
NG819_15575	COG0701	Predicted permease
NG819_15590	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NG819_15605	COG3842	ATPase activity
NG819_15630	COG2226	methyltransferase
NG819_15645	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NG819_15740	COG1609	Transcriptional regulator
NG819_15745	COG1609	Transcriptional regulator
NG819_15750	COG1653	transport
NG819_15770	COG0667	Aldo Keto reductase
NG819_15805	COG0531	amino acid
NG819_15825	COG0531	amino acid
NG819_15840	COG0363	glucosamine-6-phosphate deaminase activity
NG819_15940	COG1309	transcriptional regulator
NG819_16060	COG0202	RNA polymerase activity
NG819_16065	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NG819_16095	COG3180	Ammonia monooxygenase
NG819_16115	COG1268	BioY protein
NG819_16155	COG5002	protein histidine kinase activity
NG819_16165	COG1122	ATPase activity
NG819_16170	COG1268	BioY protein
NG819_16175	COG0477	Major facilitator Superfamily
NG819_16180	COG0439	Biotin carboxylase
NG819_16185	COG0439	Biotin carboxylase
NG819_16195	COG0511	ligase activity, forming carbon-carbon bonds
NG819_16195	COG5016	pyruvate
NG819_16200	COG0511	ligase activity, forming carbon-carbon bonds
NG819_16200	COG5016	pyruvate
NG819_16230	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NG819_16355	COG0469	pyruvate kinase activity
NG819_16370	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NG819_16375	COG0159	tryptophan synthase activity
NG819_16380	COG0133	tryptophan synthase activity
NG819_16385	COG0134	indole-3-glycerol-phosphate synthase activity
NG819_16405	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NG819_16415	COG0107	imidazoleglycerol-phosphate synthase activity
NG819_16425	COG0140	phosphoribosyl-ATP diphosphatase activity
NG819_16430	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
NG819_16470	COG0242	peptide deformylase activity
NG819_16535	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NG819_16540	COG0300	oxidoreductase activity
NG819_16545	COG1012	belongs to the aldehyde dehydrogenase family
NG819_16560	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NG819_16590	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
NG819_16595	COG0183	Belongs to the thiolase family
NG819_16640	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NG819_16645	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NG819_16655	COG0531	amino acid
NG819_16660	COG0569	domain protein
NG819_16715	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NG819_16720	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
NG819_16740	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NG819_16740	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NG819_16765	COG1131	(ABC) transporter
NG819_16780	COG1294	oxidase, subunit
NG819_16785	COG1271	oxidase subunit
NG819_16830	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NG819_16835	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NG819_16840	COG0508	dehydrogenase complex catalyzes the overall conversion of
NG819_16850	COG1764	response to oxidative stress
NG819_16860	COG1090	epimerase
NG819_16870	COG0321	lipoyl(octanoyl) transferase activity
NG819_16885	COG2409	Drug exporters of the RND superfamily
NG819_16945	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NG819_16970	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NG819_16985	COG1799	cell septum assembly
NG819_16990	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NG819_17000	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NG819_17010	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NG819_17015	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NG819_17020	COG0772	Belongs to the SEDS family
NG819_17030	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NG819_17040	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NG819_17045	COG0768	penicillin binding
NG819_17060	COG2001	Belongs to the MraZ family
NG819_17070	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NG819_17080	COG0142	geranyltranstransferase activity
NG819_17090	COG1388	LysM domain
NG819_17090	COG3942	CHAP domain
NG819_17100	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
NG819_17160	COG1716	ATPase activity
NG819_17165	COG0509	glycine decarboxylation via glycine cleavage system
NG819_17170	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
NG819_17185	COG1160	GTP binding
NG819_17195	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
NG819_17210	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NG819_17225	COG1301	dicarboxylic acid transport
NG819_17230	COG3290	protein histidine kinase activity
NG819_17250	COG2079	MmgE PrpD family protein
NG819_17275	COG0494	nUDIX hydrolase
NG819_17285	COG0497	DNA recombination
NG819_17290	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NG819_17335	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NG819_17345	COG2094	Belongs to the DNA glycosylase MPG family
NG819_17375	COG0137	argininosuccinate synthase activity
NG819_17385	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NG819_17395	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
NG819_17460	COG2814	Major facilitator Superfamily
NG819_17485	COG0291	Belongs to the bacterial ribosomal protein bL35 family
NG819_17490	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NG819_17520	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NG819_17525	COG0131	Imidazoleglycerol-phosphate dehydratase
NG819_17560	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NG819_17575	COG2137	regulation of response to DNA damage stimulus
NG819_17595	COG1396	sequence-specific DNA binding
NG819_17600	COG1058	Belongs to the CinA family
NG819_17600	COG1546	Belongs to the CinA family
NG819_17615	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NG819_17645	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
NG819_17705	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NG819_17715	COG3483	tryptophan 2,3-dioxygenase activity
NG819_17735	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NG819_17740	COG0436	Aminotransferase
NG819_17750	COG0590	tRNA wobble adenosine to inosine editing
NG819_17765	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NG819_17780	COG0195	Participates in both transcription termination and antitermination
NG819_17785	COG0779	Required for maturation of 30S ribosomal subunits
NG819_17830	COG1309	transcriptional regulator
NG819_17845	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NG819_17870	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
NG819_17900	COG1960	acyl-CoA dehydrogenase activity
NG819_17910	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NG819_17935	COG1522	sequence-specific DNA binding
NG819_17945	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NG819_17960	COG3279	Response regulator of the LytR AlgR family
NG819_17970	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NG819_17995	COG0528	UMP kinase activity
NG819_18045	COG2814	Major facilitator Superfamily
NG819_18115	COG1017	nitric oxide dioxygenase activity
NG819_18115	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NG819_18155	COG0400	carboxylic ester hydrolase activity
NG819_18225	COG0156	8-amino-7-oxononanoate synthase activity
NG819_18255	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NG819_18260	COG2851	Citrate transporter
NG819_18270	COG4565	transcriptional regulatory protein
NG819_18275	COG0251	oxidation-reduction process
NG819_18285	COG0483	inositol monophosphate 1-phosphatase activity
NG819_18325	COG0631	protein serine/threonine phosphatase activity
NG819_18340	COG0714	Associated with various cellular activities
NG819_18370	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
NG819_18370	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
NG819_18380	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NG819_18395	COG0671	phosphoesterase, PA-phosphatase related
NG819_18400	COG1823	symporter activity
NG819_18420	COG0424	maF-like protein
NG819_18440	COG0477	Major facilitator Superfamily
NG819_18495	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NG819_18520	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NG819_18565	COG0702	epimerase
NG819_18580	COG0822	iron-sulfur transferase activity
NG819_18600	COG0193	aminoacyl-tRNA hydrolase activity
NG819_18605	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NG819_18635	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NG819_18645	COG3583	domain protein
NG819_18650	COG0084	hydrolase, TatD family'
NG819_18655	COG0714	Associated with various cellular activities
NG819_18710	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
NG819_18765	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NG819_18775	COG1316	TRANSCRIPTIONal
NG819_18790	COG1494	fructose-1,6-bisphosphatase
NG819_18800	COG0288	reversible hydration of carbon dioxide
NG819_18840	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
NG819_18845	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NG819_18860	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NG819_18870	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NG819_18900	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NG819_18940	COG1252	NADH dehydrogenase
NG819_18985	COG0586	Pfam SNARE associated Golgi protein
NG819_19000	COG1079	Belongs to the binding-protein-dependent transport system permease family
NG819_19010	COG4603	Belongs to the binding-protein-dependent transport system permease family
NG819_19020	COG1744	ABC transporter substrate-binding protein PnrA-like
NG819_19025	COG2130	NADP-dependent
NG819_19030	COG1764	response to oxidative stress
NG819_19035	COG1846	Transcriptional regulator
NG819_19040	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
NG819_19040	COG1473	amidohydrolase
NG819_19050	COG2009	succinate dehydrogenase
NG819_19065	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NG819_19090	COG0180	Tryptophanyl-tRNA synthetase
NG819_19095	COG0708	Exodeoxyribonuclease III
NG819_19115	COG4585	Histidine kinase
NG819_19120	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NG819_19125	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NG819_19145	COG0531	amino acid
NG819_19175	COG4213	ABC transporter substrate-binding protein
NG819_19185	COG1136	(ABC) transporter
NG819_19265	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
NG819_19270	COG0438	transferase activity, transferring glycosyl groups
NG819_19275	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NG819_19300	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NG819_19325	COG1414	Transcriptional regulator
NG819_19335	COG0833	amino acid
NG819_19350	COG1012	belongs to the aldehyde dehydrogenase family
NG819_19425	COG1278	Cold shock
NG819_19525	COG1802	Transcriptional regulator
NG819_19540	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NG819_19545	COG0601	transmembrane transport
NG819_19550	COG0747	negative chemotaxis
NG819_19555	COG3619	membrane
NG819_19565	COG1028	Short-chain dehydrogenase reductase Sdr
NG819_19580	COG3836	Belongs to the HpcH HpaI aldolase family
NG819_19585	COG0667	Aldo Keto reductase
NG819_19590	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
NG819_19600	COG0477	Major facilitator Superfamily
NG819_19610	COG2350	Protein conserved in bacteria
NG819_19620	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
NG819_19650	COG0673	inositol 2-dehydrogenase activity
NG819_19655	COG1172	Belongs to the binding-protein-dependent transport system permease family
NG819_19680	COG1609	Transcriptional regulator
NG819_19690	COG4942	peptidase
NG819_19695	COG4942	peptidase
NG819_19730	COG2186	Transcriptional regulator
NG819_19740	COG2337	Toxic component of a toxin-antitoxin (TA) module
NG819_19755	COG0477	Major facilitator Superfamily
NG819_19765	COG0456	acetyltransferase
NG819_19820	COG2815	serine threonine protein kinase
NG819_19820	COG0515	serine threonine protein kinase
NG819_19870	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NG819_19945	COG0574	Belongs to the PEP-utilizing enzyme family
NG819_19945	COG3848	Pyruvate phosphate dikinase
NG819_19990	COG3511	phospholipase C
NG819_19995	COG3511	phospholipase C
NG819_20000	COG1028	Short-chain dehydrogenase reductase Sdr
NG819_20085	COG1556	Lactate utilization protein
NG819_20100	COG1620	l-lactate permease
NG819_20170	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
NG819_20225	COG0673	inositol 2-dehydrogenase activity
NG819_20230	COG1472	Belongs to the glycosyl hydrolase 3 family
NG819_20245	COG0395	ABC-type sugar transport system, permease component
NG819_20250	COG4209	transmembrane transport
NG819_20350	COG0640	Transcriptional regulator
NG819_20360	COG0395	ABC-type sugar transport system, permease component
NG819_20370	COG1175	transmembrane transport
NG819_20380	COG2186	Transcriptional regulator
NG819_20415	COG0179	Fumarylacetoacetate (FAA) hydrolase
NG819_20425	COG1253	flavin adenine dinucleotide binding
NG819_20460	COG1063	alcohol dehydrogenase
NG819_20480	COG1254	Belongs to the acylphosphatase family
NG819_20490	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NG819_20495	COG1652	LysM domain
NG819_20510	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NG819_20615	COG0477	Major facilitator Superfamily
NG819_20625	COG0028	Belongs to the TPP enzyme family
NG819_20675	COG2814	Major facilitator Superfamily
NG819_20685	COG2814	Major facilitator Superfamily
NG819_20690	COG0673	inositol 2-dehydrogenase activity
NG819_20725	COG0640	Transcriptional regulator
NG819_20735	COG0149	triose-phosphate isomerase activity
NG819_20745	COG1028	Short-chain dehydrogenase reductase Sdr
NG819_20750	COG1250	3-hydroxyacyl-CoA dehydrogenase
NG819_20755	COG0698	ribose 5-phosphate isomerase
NG819_20760	COG2376	Dihydroxyacetone kinase
NG819_20805	COG1090	epimerase
NG819_20825	COG0483	inositol monophosphate 1-phosphatase activity
NG819_20850	COG0494	nUDIX hydrolase
NG819_20855	COG1132	(ABC) transporter
NG819_20920	COG0739	heme binding
NG819_20940	COG1278	Cold shock
NG819_20965	COG0745	RESPONSE REGULATOR receiver
NG819_20985	COG1653	transport
NG819_21040	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
NG819_21050	COG0404	The glycine cleavage system catalyzes the degradation of glycine
NG819_21090	COG1609	Transcriptional regulator
NG819_21110	COG4213	ABC transporter substrate-binding protein
NG819_21115	COG1129	ABC transporter
NG819_21205	COG0366	Alpha amylase catalytic
NG819_21210	COG1609	Transcriptional regulator
NG819_21275	COG0215	cysteine-tRNA ligase activity
NG819_21280	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
NG819_21285	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
NG819_21335	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NG819_21340	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NG819_21460	COG1136	(ABC) transporter
NG819_21460	COG0577	efflux transmembrane transporter activity
NG819_21515	COG1192	Involved in chromosome partitioning
NG819_21550	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
NG819_21560	COG2135	peptidase activity
NG819_21585	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NG819_21640	COG0671	phosphoesterase, PA-phosphatase related
NG819_21645	COG1475	DNA binding
NG819_21885	COG1192	Involved in chromosome partitioning
NG819_21925	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs