locus-tag	class	description
ArtHe_00010	COG0277	FAD linked oxidase domain protein
ArtHe_00015	COG0366	Alpha amylase catalytic
ArtHe_00030	COG3842	ATPase activity
ArtHe_00035	COG1877	trehalose-phosphatase activity
ArtHe_00065	COG3655	Transcriptional regulator
ArtHe_00070	COG0697	spore germination
ArtHe_00075	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ArtHe_00085	COG1574	metal-dependent hydrolase with the TIM-barrel fold
ArtHe_00095	COG0601	transmembrane transport
ArtHe_00100	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ArtHe_00105	COG4172	Belongs to the ABC transporter superfamily
ArtHe_00110	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ArtHe_00125	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ArtHe_00130	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ArtHe_00145	COG1335	isochorismatase
ArtHe_00170	COG3226	Transcriptional regulator
ArtHe_00175	COG0747	negative chemotaxis
ArtHe_00185	COG0444	Belongs to the ABC transporter superfamily
ArtHe_00190	COG4172	Belongs to the ABC transporter superfamily
ArtHe_00195	COG2814	Major facilitator Superfamily
ArtHe_00205	COG0657	acetylesterase activity
ArtHe_00210	COG1028	Short-chain dehydrogenase reductase Sdr
ArtHe_00240	COG0667	Aldo Keto reductase
ArtHe_00245	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
ArtHe_00250	COG1063	alcohol dehydrogenase
ArtHe_00255	COG0667	Aldo Keto reductase
ArtHe_00275	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ArtHe_00275	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ArtHe_00300	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
ArtHe_00325	COG1802	Transcriptional regulator
ArtHe_00345	COG0667	Aldo Keto reductase
ArtHe_00380	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ArtHe_00395	COG1278	Cold shock
ArtHe_00405	COG0459	protein refolding
ArtHe_00415	COG2205	protein histidine kinase activity
ArtHe_00420	COG0745	RESPONSE REGULATOR receiver
ArtHe_00440	COG1278	Cold shock
ArtHe_00465	COG0739	heme binding
ArtHe_00465	COG0741	lytic transglycosylase activity
ArtHe_00465	COG1196	nuclear chromosome segregation
ArtHe_00475	COG3103	Sh3 type 3 domain protein
ArtHe_00475	COG0791	NLP P60 protein
ArtHe_00475	COG1388	LysM domain
ArtHe_00485	COG0746	molybdenum cofactor guanylyltransferase activity
ArtHe_00495	COG0303	'Molybdopterin
ArtHe_00505	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ArtHe_00510	COG5002	protein histidine kinase activity
ArtHe_00515	COG1132	(ABC) transporter
ArtHe_00555	COG0483	inositol monophosphate 1-phosphatase activity
ArtHe_00565	COG0045	succinate-CoA ligase (ADP-forming) activity
ArtHe_00575	COG2814	Major facilitator Superfamily
ArtHe_00600	COG0318	PFAM AMP-dependent synthetase and ligase
ArtHe_00610	COG1396	sequence-specific DNA binding
ArtHe_00620	COG0583	DNA-binding transcription factor activity
ArtHe_00625	COG2814	Major facilitator Superfamily
ArtHe_00645	COG0028	Belongs to the TPP enzyme family
ArtHe_00665	COG3424	synthase
ArtHe_00700	COG1028	Short-chain dehydrogenase reductase Sdr
ArtHe_00710	COG0028	Belongs to the TPP enzyme family
ArtHe_00725	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ArtHe_00735	COG0252	asparaginase activity
ArtHe_00760	COG1595	DNA-templated transcription, initiation
ArtHe_00785	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
ArtHe_00790	COG0028	Belongs to the TPP enzyme family
ArtHe_00795	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ArtHe_00800	COG2390	Transcriptional regulator
ArtHe_00820	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ArtHe_00825	COG0730	response to heat
ArtHe_00855	COG3265	gluconokinase activity
ArtHe_00860	COG2610	gluconate transmembrane transporter activity
ArtHe_00865	COG1028	Short-chain dehydrogenase reductase Sdr
ArtHe_00870	COG1063	alcohol dehydrogenase
ArtHe_00900	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ArtHe_00910	COG0590	tRNA wobble adenosine to inosine editing
ArtHe_00945	COG0640	Transcriptional regulator
ArtHe_00950	COG1609	Transcriptional regulator
ArtHe_00955	COG0252	asparaginase activity
ArtHe_00970	COG1028	Short-chain dehydrogenase reductase Sdr
ArtHe_00975	COG1028	Short-chain dehydrogenase reductase Sdr
ArtHe_01025	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ArtHe_01040	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ArtHe_01060	COG2365	Tyrosine phosphatase family
ArtHe_01065	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ArtHe_01070	COG1840	ABC-type Fe3 transport system, periplasmic component
ArtHe_01075	COG1178	ABC-type Fe3 transport system permease component
ArtHe_01080	COG3842	ATPase activity
ArtHe_01105	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ArtHe_01115	COG0006	proline dipeptidase activity
ArtHe_01125	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ArtHe_01130	COG0247	lactate metabolic process
ArtHe_01130	COG0277	FAD linked oxidase domain protein
ArtHe_01140	COG0477	Major facilitator Superfamily
ArtHe_01175	COG2161	toxin-antitoxin pair type II binding
ArtHe_01200	COG1802	Transcriptional regulator
ArtHe_01220	COG1609	Transcriptional regulator
ArtHe_01240	COG1473	amidohydrolase
ArtHe_01245	COG0154	amidase activity
ArtHe_01250	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ArtHe_01260	COG3842	ATPase activity
ArtHe_01275	COG1609	Transcriptional regulator
ArtHe_01295	COG1879	ABC-type sugar transport system periplasmic component
ArtHe_01300	COG1129	ABC transporter
ArtHe_01305	COG1172	Belongs to the binding-protein-dependent transport system permease family
ArtHe_01310	COG1940	carbohydrate kinase activity
ArtHe_01320	COG0154	amidase activity
ArtHe_01325	COG2957	Belongs to the agmatine deiminase family
ArtHe_01330	COG1228	amidohydrolase
ArtHe_01370	COG1940	carbohydrate kinase activity
ArtHe_01375	COG2115	Belongs to the xylose isomerase family
ArtHe_01385	COG2814	Major facilitator Superfamily
ArtHe_01415	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ArtHe_01415	COG3153	acetyltransferase
ArtHe_01435	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ArtHe_01445	COG0667	Aldo Keto reductase
ArtHe_01465	COG0363	glucosamine-6-phosphate deaminase activity
ArtHe_01475	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ArtHe_01480	COG0165	Argininosuccinate lyase
ArtHe_01485	COG4149	molybdate abc transporter
ArtHe_01490	COG3842	ATPase activity
ArtHe_01500	COG1940	carbohydrate kinase activity
ArtHe_01505	COG0277	FAD linked oxidase domain protein
ArtHe_01510	COG2197	response regulator
ArtHe_01515	COG4585	Histidine kinase
ArtHe_01520	COG2188	Transcriptional regulator
ArtHe_01525	COG1620	l-lactate permease
ArtHe_01530	COG0247	lactate metabolic process
ArtHe_01535	COG1139	Iron-sulfur cluster binding protein
ArtHe_01540	COG1556	Lactate utilization protein
ArtHe_01545	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ArtHe_01555	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ArtHe_01570	COG3971	2-oxopent-4-enoate hydratase activity
ArtHe_01580	COG1620	l-lactate permease
ArtHe_01595	COG3619	membrane
ArtHe_01600	COG0039	L-malate dehydrogenase activity
ArtHe_01605	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ArtHe_01640	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ArtHe_01645	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ArtHe_01660	COG3842	ATPase activity
ArtHe_01665	COG1176	ABC-type spermidine putrescine transport system, permease component I
ArtHe_01670	COG1177	transmembrane transport
ArtHe_01685	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ArtHe_01700	COG1278	Cold shock
ArtHe_01705	COG2066	Belongs to the glutaminase family
ArtHe_01705	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
ArtHe_01710	COG1278	Cold shock
ArtHe_01730	COG0515	serine threonine protein kinase
ArtHe_01730	COG2815	serine threonine protein kinase
ArtHe_01735	COG3012	SEC-C Motif Domain Protein
ArtHe_01740	COG1063	alcohol dehydrogenase
ArtHe_01745	COG1063	alcohol dehydrogenase
ArtHe_01760	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
ArtHe_01765	COG0829	nickel cation binding
ArtHe_01770	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
ArtHe_01780	COG0804	urea catabolic process
ArtHe_01785	COG0832	Belongs to the urease beta subunit family
ArtHe_01790	COG0831	urea catabolic process
ArtHe_01800	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ArtHe_01810	COG0753	catalase activity
ArtHe_01870	COG0477	Major facilitator Superfamily
ArtHe_01925	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ArtHe_01930	COG0747	negative chemotaxis
ArtHe_01940	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ArtHe_01950	COG1619	proteins homologs of microcin C7 resistance protein MccF
ArtHe_01980	COG1136	(ABC) transporter
ArtHe_01990	COG0673	inositol 2-dehydrogenase activity
ArtHe_02005	COG4213	ABC transporter substrate-binding protein
ArtHe_02010	COG4214	carbohydrate transport
ArtHe_02015	COG1129	ABC transporter
ArtHe_02040	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ArtHe_02045	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ArtHe_02065	COG2197	response regulator
ArtHe_02070	COG4585	Histidine kinase
ArtHe_02095	COG0180	Tryptophanyl-tRNA synthetase
ArtHe_02110	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ArtHe_02125	COG2009	succinate dehydrogenase
ArtHe_02135	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
ArtHe_02135	COG1473	amidohydrolase
ArtHe_02140	COG1744	ABC transporter substrate-binding protein PnrA-like
ArtHe_02145	COG3845	ABC transporter
ArtHe_02150	COG4603	Belongs to the binding-protein-dependent transport system permease family
ArtHe_02155	COG1079	Belongs to the binding-protein-dependent transport system permease family
ArtHe_02170	COG0586	Pfam SNARE associated Golgi protein
ArtHe_02175	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ArtHe_02180	COG3956	TIGRFAM MazG family protein
ArtHe_02185	COG0148	phosphopyruvate hydratase activity
ArtHe_02220	COG0683	leucine binding
ArtHe_02240	COG0559	Belongs to the binding-protein-dependent transport system permease family
ArtHe_02255	COG2017	converts alpha-aldose to the beta-anomer
ArtHe_02265	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ArtHe_02270	COG0705	Rhomboid family
ArtHe_02275	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ArtHe_02285	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ArtHe_02295	COG1331	Highly conserved protein containing a thioredoxin domain
ArtHe_02305	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ArtHe_02310	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ArtHe_02340	COG0114	fumarate hydratase activity
ArtHe_02345	COG0288	reversible hydration of carbon dioxide
ArtHe_02355	COG1494	fructose-1,6-bisphosphatase
ArtHe_02375	COG1316	TRANSCRIPTIONal
ArtHe_02430	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
ArtHe_02480	COG0714	Associated with various cellular activities
ArtHe_02485	COG0084	hydrolase, TatD family'
ArtHe_02510	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ArtHe_02515	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ArtHe_02520	COG0488	(ABC) transporter
ArtHe_02540	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ArtHe_02545	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ArtHe_02550	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ArtHe_02555	COG0193	aminoacyl-tRNA hydrolase activity
ArtHe_02575	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ArtHe_02580	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ArtHe_02590	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ArtHe_02605	COG0438	transferase activity, transferring glycosyl groups
ArtHe_02665	COG1129	ABC transporter
ArtHe_02675	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ArtHe_02685	COG0822	iron-sulfur transferase activity
ArtHe_02690	COG5002	protein histidine kinase activity
ArtHe_02695	COG0745	RESPONSE REGULATOR receiver
ArtHe_02705	COG1012	belongs to the aldehyde dehydrogenase family
ArtHe_02740	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ArtHe_02770	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ArtHe_02775	COG1012	belongs to the aldehyde dehydrogenase family
ArtHe_02790	COG3842	ATPase activity
ArtHe_02795	COG1177	transmembrane transport
ArtHe_02810	COG3281	Trehalose synthase
ArtHe_02830	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ArtHe_02855	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ArtHe_02870	COG0477	Major facilitator Superfamily
ArtHe_02875	COG4770	biotin carboxylase activity
ArtHe_02880	COG0424	maF-like protein
ArtHe_02885	COG1823	symporter activity
ArtHe_02900	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ArtHe_02905	COG1028	Short-chain dehydrogenase reductase Sdr
ArtHe_02930	COG0714	Associated with various cellular activities
ArtHe_02940	COG1305	Transglutaminase-like
ArtHe_02980	COG1674	ftsk spoiiie
ArtHe_03030	COG4941	Belongs to the sigma-70 factor family
ArtHe_03040	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ArtHe_03055	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ArtHe_03065	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ArtHe_03070	COG0154	amidase activity
ArtHe_03075	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ArtHe_03100	COG1254	Belongs to the acylphosphatase family
ArtHe_03105	COG2986	histidine ammonia-lyase
ArtHe_03115	COG3250	beta-galactosidase activity
ArtHe_03130	COG2873	o-acetylhomoserine
ArtHe_03135	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ArtHe_03160	COG0423	glycine-tRNA ligase activity
ArtHe_03170	COG1309	transcriptional regulator
ArtHe_03175	COG1511	domain protein
ArtHe_03180	COG4133	protoheme IX ABC transporter activity
ArtHe_03200	COG0358	DNA primase activity
ArtHe_03230	COG0477	Major facilitator Superfamily
ArtHe_03250	COG0297	glycogen (starch) synthase activity
ArtHe_03270	COG0052	Belongs to the universal ribosomal protein uS2 family
ArtHe_03275	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ArtHe_03280	COG0528	UMP kinase activity
ArtHe_03285	COG0233	cytoplasmic translational termination
ArtHe_03290	COG0575	Belongs to the CDS family
ArtHe_03300	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ArtHe_03315	COG3275	phosphorelay sensor kinase activity
ArtHe_03325	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ArtHe_03330	COG1522	sequence-specific DNA binding
ArtHe_03340	COG0022	dehydrogenase e1 component
ArtHe_03345	COG0508	dehydrogenase complex catalyzes the overall conversion of
ArtHe_03355	COG1309	transcriptional regulator
ArtHe_03360	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ArtHe_03370	COG1960	acyl-CoA dehydrogenase activity
ArtHe_03400	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ArtHe_03405	COG0750	zinc metalloprotease
ArtHe_03425	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ArtHe_03435	COG2807	transmembrane transport
ArtHe_03440	COG2186	Transcriptional regulator
ArtHe_03445	COG0442	prolyl-tRNA aminoacylation
ArtHe_03465	COG0779	Required for maturation of 30S ribosomal subunits
ArtHe_03470	COG0195	Participates in both transcription termination and antitermination
ArtHe_03480	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ArtHe_03485	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ArtHe_03500	COG0436	Aminotransferase
ArtHe_03505	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ArtHe_03525	COG0196	riboflavin kinase activity
ArtHe_03530	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ArtHe_03535	COG1185	polyribonucleotide nucleotidyltransferase activity
ArtHe_03540	COG0612	Peptidase, M16
ArtHe_03555	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ArtHe_03570	COG0315	cyclic pyranopterin monophosphate synthase activity
ArtHe_03575	COG0521	Mo-molybdopterin cofactor biosynthetic process
ArtHe_03585	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ArtHe_03595	COG2814	Major facilitator Superfamily
ArtHe_03600	COG5504	Zn-dependent protease
ArtHe_03610	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ArtHe_03615	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ArtHe_03620	COG1674	ftsk spoiiie
ArtHe_03630	COG1546	Belongs to the CinA family
ArtHe_03630	COG1058	Belongs to the CinA family
ArtHe_03635	COG1396	sequence-specific DNA binding
ArtHe_03650	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ArtHe_03670	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ArtHe_03675	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ArtHe_03680	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ArtHe_03685	COG2813	Specifically methylates the guanine in position
ArtHe_03690	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ArtHe_03700	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ArtHe_03710	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ArtHe_03715	COG0131	Imidazoleglycerol-phosphate dehydratase
ArtHe_03720	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ArtHe_03730	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ArtHe_03750	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ArtHe_03755	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ArtHe_03760	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ArtHe_03765	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ArtHe_03775	COG2814	Major facilitator Superfamily
ArtHe_03795	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ArtHe_03800	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ArtHe_03800	COG0072	phenylalanine-tRNA ligase activity
ArtHe_03820	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ArtHe_03825	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ArtHe_03830	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ArtHe_03835	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ArtHe_03840	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ArtHe_03845	COG1438	arginine binding
ArtHe_03850	COG0137	argininosuccinate synthase activity
ArtHe_03855	COG0165	Argininosuccinate lyase
ArtHe_03860	COG0259	pyridoxamine-phosphate oxidase activity
ArtHe_03870	COG2094	Belongs to the DNA glycosylase MPG family
ArtHe_03875	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ArtHe_03885	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ArtHe_03920	COG0647	UMP catabolic process
ArtHe_03935	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ArtHe_03940	COG0497	DNA recombination
ArtHe_03945	COG0504	CTP synthase activity
ArtHe_03950	COG0494	nUDIX hydrolase
ArtHe_03980	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
ArtHe_03985	COG2079	MmgE PrpD family protein
ArtHe_04005	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ArtHe_04010	COG4565	transcriptional regulatory protein
ArtHe_04015	COG3290	protein histidine kinase activity
ArtHe_04040	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ArtHe_04055	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ArtHe_04060	COG1160	GTP binding
ArtHe_04145	COG0804	urea catabolic process
ArtHe_04150	COG0830	nickel cation binding
ArtHe_04155	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
ArtHe_04160	COG0829	nickel cation binding
ArtHe_04165	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
ArtHe_04175	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ArtHe_04180	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ArtHe_04235	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ArtHe_04245	COG1733	regulation of RNA biosynthetic process
ArtHe_04250	COG2910	NAD(P)H-binding
ArtHe_04255	COG0477	Major facilitator Superfamily
ArtHe_04270	COG1716	ATPase activity
ArtHe_04295	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
ArtHe_04310	COG1940	carbohydrate kinase activity
ArtHe_04330	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
ArtHe_04335	COG2815	serine threonine protein kinase
ArtHe_04335	COG0515	serine threonine protein kinase
ArtHe_04340	COG3942	CHAP domain
ArtHe_04340	COG1388	LysM domain
ArtHe_04350	COG0142	geranyltranstransferase activity
ArtHe_04360	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ArtHe_04370	COG2001	Belongs to the MraZ family
ArtHe_04375	COG0275	rRNA processing
ArtHe_04385	COG0768	penicillin binding
ArtHe_04400	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ArtHe_04405	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ArtHe_04415	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ArtHe_04420	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ArtHe_04425	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ArtHe_04430	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ArtHe_04435	COG1496	oxidoreductase activity
ArtHe_04445	COG1799	cell septum assembly
ArtHe_04460	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ArtHe_04470	COG0587	DNA-directed DNA polymerase activity
ArtHe_04475	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ArtHe_04480	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ArtHe_04500	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ArtHe_04505	COG0174	glutamine synthetase
ArtHe_04510	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
ArtHe_04515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ArtHe_04520	COG1126	abc transporter atp-binding protein
ArtHe_04545	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ArtHe_04550	COG0321	lipoyl(octanoyl) transferase activity
ArtHe_04560	COG0793	Belongs to the peptidase S41A family
ArtHe_04560	COG4946	Tricorn protease homolog
ArtHe_04565	COG1764	response to oxidative stress
ArtHe_04575	COG0508	dehydrogenase complex catalyzes the overall conversion of
ArtHe_04580	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ArtHe_04585	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ArtHe_04605	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ArtHe_04610	COG2271	Major facilitator Superfamily
ArtHe_04625	COG0187	DNA topoisomerase II activity
ArtHe_04630	COG0501	Belongs to the peptidase M48B family
ArtHe_04640	COG1271	oxidase subunit
ArtHe_04645	COG1294	oxidase, subunit
ArtHe_04650	COG4988	ABC transporter
ArtHe_04670	COG4176	ABC-type proline glycine betaine transport system permease component
ArtHe_04675	COG0517	IMP dehydrogenase activity
ArtHe_04675	COG4175	Glycine betaine
ArtHe_04680	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ArtHe_04700	COG1435	thymidine kinase activity
ArtHe_04720	COG0756	dUTP diphosphatase activity
ArtHe_04745	COG0569	domain protein
ArtHe_04750	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ArtHe_04755	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ArtHe_04760	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ArtHe_04775	COG0667	Aldo Keto reductase
ArtHe_04790	COG0598	Magnesium transport protein CorA
ArtHe_04840	COG1024	Enoyl-CoA hydratase
ArtHe_04840	COG1250	3-hydroxyacyl-CoA dehydrogenase
ArtHe_04845	COG0183	Belongs to the thiolase family
ArtHe_04880	COG1595	DNA-templated transcription, initiation
ArtHe_04910	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
ArtHe_04915	COG0183	Belongs to the thiolase family
ArtHe_04930	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
ArtHe_04955	COG1269	ATP hydrolysis coupled proton transport
ArtHe_04975	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ArtHe_05010	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ArtHe_05080	COG0242	peptide deformylase activity
ArtHe_05085	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ArtHe_05095	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ArtHe_05105	COG0488	(ABC) transporter
ArtHe_05125	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ArtHe_05125	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ArtHe_05130	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ArtHe_05130	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ArtHe_05135	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ArtHe_05150	COG0477	Major facilitator Superfamily
ArtHe_05155	COG0402	S-adenosylhomocysteine deaminase activity
ArtHe_05160	COG3795	YCII-related domain
ArtHe_05170	COG0402	S-adenosylhomocysteine deaminase activity
ArtHe_05180	COG0140	phosphoribosyl-ATP diphosphatase activity
ArtHe_05185	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ArtHe_05190	COG0107	imidazoleglycerol-phosphate synthase activity
ArtHe_05200	COG2315	Protein conserved in bacteria
ArtHe_05210	COG1064	alcohol dehydrogenase
ArtHe_05220	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ArtHe_05240	COG0134	indole-3-glycerol-phosphate synthase activity
ArtHe_05245	COG0133	tryptophan synthase activity
ArtHe_05250	COG0159	tryptophan synthase activity
ArtHe_05255	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ArtHe_05260	COG0067	glutamate synthase
ArtHe_05260	COG0069	glutamate synthase activity
ArtHe_05260	COG0070	glutamate synthase
ArtHe_05270	COG0469	pyruvate kinase activity
ArtHe_05300	COG2814	Major facilitator Superfamily
ArtHe_05310	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ArtHe_05330	COG0385	Bile acid
ArtHe_05365	COG1940	carbohydrate kinase activity
ArtHe_05395	COG0471	metal ion transport
ArtHe_05420	COG1846	Transcriptional regulator
ArtHe_05430	COG1132	(ABC) transporter
ArtHe_05470	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ArtHe_05475	COG0798	PFAM Bile acid sodium symporter
ArtHe_05480	COG0640	Transcriptional regulator
ArtHe_05485	COG2890	protein-(glutamine-N5) methyltransferase activity
ArtHe_05490	COG3585	molybdate ion transport
ArtHe_05510	COG0667	Aldo Keto reductase
ArtHe_05515	COG1653	transport
ArtHe_05520	COG1175	transmembrane transport
ArtHe_05525	COG1175	transmembrane transport
ArtHe_05535	COG1357	PFAM Pentapeptide repeats (8 copies)
ArtHe_05540	COG3173	Aminoglycoside phosphotransferase
ArtHe_05545	COG1464	Belongs to the NlpA lipoprotein family
ArtHe_05550	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ArtHe_05560	COG1643	Atp-dependent helicase
ArtHe_05575	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ArtHe_05600	COG1120	ATPase activity
ArtHe_05605	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ArtHe_05620	COG4335	DNA alkylation repair
ArtHe_05635	COG1937	Protein conserved in bacteria
ArtHe_05645	COG1785	Belongs to the alkaline phosphatase family
ArtHe_05650	COG0009	L-threonylcarbamoyladenylate synthase
ArtHe_05665	COG0477	Major facilitator Superfamily
ArtHe_05670	COG3285	dna ligase
ArtHe_05670	COG1793	dna ligase
ArtHe_05675	COG0778	Nitroreductase
ArtHe_05705	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
ArtHe_05715	COG2272	Belongs to the type-B carboxylesterase lipase family
ArtHe_05720	COG0488	(ABC) transporter
ArtHe_05730	COG2272	Belongs to the type-B carboxylesterase lipase family
ArtHe_05745	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ArtHe_05750	COG1793	dna ligase
ArtHe_05755	COG1607	acyl-coa hydrolase
ArtHe_05760	COG2807	transmembrane transport
ArtHe_05765	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ArtHe_05775	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ArtHe_05780	COG1082	Xylose isomerase domain protein TIM barrel
ArtHe_05780	COG3185	4-Hydroxyphenylpyruvate dioxygenase
ArtHe_05785	COG1414	Transcriptional regulator
ArtHe_05790	COG2066	Belongs to the glutaminase family
ArtHe_05795	COG0531	amino acid
ArtHe_05800	COG0076	glutamate decarboxylase activity
ArtHe_05810	COG0477	Major facilitator Superfamily
ArtHe_05815	COG2050	protein possibly involved in aromatic compounds catabolism
ArtHe_05825	COG4552	Acetyltransferase involved in intracellular survival and related
ArtHe_05830	COG0539	negative regulation of cytoplasmic translation
ArtHe_05845	COG2723	6-phospho-beta-galactosidase activity
ArtHe_05850	COG0395	ABC-type sugar transport system, permease component
ArtHe_05870	COG1739	Uncharacterized protein family UPF0029
ArtHe_05875	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
ArtHe_05875	COG0237	dephospho-CoA kinase activity
ArtHe_05880	COG0556	nucleotide-excision repair
ArtHe_05920	COG4106	trans-aconitate 2-methyltransferase activity
ArtHe_05960	COG0322	excinuclease ABC activity
ArtHe_05965	COG1660	Displays ATPase and GTPase activities
ArtHe_05975	COG1481	regulation of sporulation
ArtHe_05980	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ArtHe_05990	COG0126	phosphoglycerate kinase activity
ArtHe_05995	COG0149	triose-phosphate isomerase activity
ArtHe_06000	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ArtHe_06005	COG0363	glucosamine-6-phosphate deaminase activity
ArtHe_06025	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ArtHe_06035	COG0109	protoheme IX farnesyltransferase activity
ArtHe_06040	COG1612	heme a metabolic process
ArtHe_06050	COG1131	(ABC) transporter
ArtHe_06070	COG0396	ATPase activity
ArtHe_06075	COG2151	metal-sulfur cluster biosynthetic enzyme
ArtHe_06085	COG1122	ATPase activity
ArtHe_06090	COG1268	BioY protein
ArtHe_06095	COG0488	(ABC) transporter
ArtHe_06115	COG1028	Short-chain dehydrogenase reductase Sdr
ArtHe_06120	COG1028	Short-chain dehydrogenase reductase Sdr
ArtHe_06125	COG0560	Phosphoserine phosphatase
ArtHe_06125	COG3830	Belongs to the UPF0237 family
ArtHe_06130	COG1119	ATPase activity
ArtHe_06150	COG0254	rRNA binding
ArtHe_06170	COG2855	membrane
ArtHe_06175	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ArtHe_06190	COG0297	glycogen (starch) synthase activity
ArtHe_06210	COG1028	Short-chain dehydrogenase reductase Sdr
ArtHe_06225	COG0589	response to stress
ArtHe_06235	COG1253	flavin adenine dinucleotide binding
ArtHe_06245	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ArtHe_06265	COG1968	undecaprenyl-diphosphatase activity
ArtHe_06270	COG0215	cysteine-tRNA ligase activity
ArtHe_06285	COG0517	IMP dehydrogenase activity
ArtHe_06285	COG1994	Peptidase M50
ArtHe_06295	COG1222	aaa ATPase
ArtHe_06300	COG4122	O-methyltransferase activity
ArtHe_06310	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
ArtHe_06315	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
ArtHe_06320	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
ArtHe_06345	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ArtHe_06350	COG0805	protein transport
ArtHe_06355	COG4581	dead DEAH box helicase
ArtHe_06360	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
ArtHe_06365	COG1216	Glycosyl transferase, family 2
ArtHe_06390	COG0823	Involved in the tonB-independent uptake of proteins
ArtHe_06390	COG1506	peptidase
ArtHe_06390	COG4946	Tricorn protease homolog
ArtHe_06395	COG0242	peptide deformylase activity
ArtHe_06410	COG1846	Transcriptional regulator
ArtHe_06410	COG1940	carbohydrate kinase activity
ArtHe_06420	COG1175	transmembrane transport
ArtHe_06430	COG1472	Belongs to the glycosyl hydrolase 3 family
ArtHe_06440	COG1028	Short-chain dehydrogenase reductase Sdr
ArtHe_06465	COG1136	(ABC) transporter
ArtHe_06485	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ArtHe_06490	COG1845	cytochrome c oxidase, subunit III
ArtHe_06495	COG2010	Cytochrome c
ArtHe_06500	COG0723	plastoquinol--plastocyanin reductase activity
ArtHe_06505	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ArtHe_06515	COG2188	Transcriptional regulator
ArtHe_06525	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ArtHe_06530	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ArtHe_06550	COG0167	dihydroorotate dehydrogenase activity
ArtHe_06560	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ArtHe_06565	COG1381	Involved in DNA repair and RecF pathway recombination
ArtHe_06570	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ArtHe_06575	COG1316	TRANSCRIPTIONal
ArtHe_06580	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ArtHe_06590	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ArtHe_06610	COG0484	heat shock protein binding
ArtHe_06615	COG1420	regulation of RNA biosynthetic process
ArtHe_06635	COG0481	GTPase activity
ArtHe_06645	COG0268	Binds directly to 16S ribosomal RNA
ArtHe_06675	COG0658	competence protein
ArtHe_06675	COG2333	competence protein COMEC
ArtHe_06685	COG1307	EDD domain protein, DegV family
ArtHe_06690	COG0495	leucyl-tRNA aminoacylation
ArtHe_06695	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ArtHe_06700	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ArtHe_06705	COG0656	L-ascorbic acid biosynthetic process
ArtHe_06710	COG0596	Alpha beta hydrolase
ArtHe_06715	COG0438	transferase activity, transferring glycosyl groups
ArtHe_06720	COG2130	NADP-dependent
ArtHe_06745	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ArtHe_06755	COG1758	RNA polymerase activity
ArtHe_06760	COG0194	GDP metabolic process
ArtHe_06765	COG0194	GDP metabolic process
ArtHe_06770	COG0284	orotidine-5'-phosphate decarboxylase activity
ArtHe_06775	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ArtHe_06780	COG0505	Belongs to the CarA family
ArtHe_06790	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ArtHe_06795	COG0540	Belongs to the ATCase OTCase family
ArtHe_06800	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
ArtHe_06810	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ArtHe_06815	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ArtHe_06820	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ArtHe_06825	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ArtHe_06830	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ArtHe_06835	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ArtHe_06850	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ArtHe_06865	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ArtHe_06875	COG0384	phenazine biosynthesis protein PhzF
ArtHe_06890	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ArtHe_06900	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ArtHe_06915	COG1476	TRANSCRIPTIONal
ArtHe_06950	COG0395	ABC-type sugar transport system, permease component
ArtHe_06955	COG1175	transmembrane transport
ArtHe_06965	COG1940	carbohydrate kinase activity
ArtHe_06970	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ArtHe_07000	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ArtHe_07005	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ArtHe_07010	COG1116	anion transmembrane transporter activity
ArtHe_07015	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ArtHe_07025	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ArtHe_07040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ArtHe_07050	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
ArtHe_07050	COG0778	Nitroreductase
ArtHe_07055	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ArtHe_07060	COG0124	histidyl-tRNA synthetase
ArtHe_07070	COG1196	nuclear chromosome segregation
ArtHe_07080	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ArtHe_07085	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ArtHe_07090	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ArtHe_07100	COG2255	four-way junction helicase activity
ArtHe_07105	COG0632	four-way junction helicase activity
ArtHe_07110	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ArtHe_07115	COG0217	transcriptional regulatory protein
ArtHe_07120	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
ArtHe_07160	COG0277	FAD linked oxidase domain protein
ArtHe_07205	COG1309	transcriptional regulator
ArtHe_07240	COG2197	response regulator
ArtHe_07250	COG0339	signal peptide processing
ArtHe_07260	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
ArtHe_07265	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ArtHe_07275	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ArtHe_07280	COG0587	DNA-directed DNA polymerase activity
ArtHe_07305	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ArtHe_07315	COG2409	Drug exporters of the RND superfamily
ArtHe_07385	COG0667	Aldo Keto reductase
ArtHe_07390	COG2135	peptidase activity
ArtHe_07415	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ArtHe_07450	COG0667	Aldo Keto reductase
ArtHe_07455	COG0442	prolyl-tRNA aminoacylation
ArtHe_07470	COG1028	Short-chain dehydrogenase reductase Sdr
ArtHe_07480	COG0039	L-malate dehydrogenase activity
ArtHe_07485	COG4948	Mandelate Racemase Muconate Lactonizing
ArtHe_07490	COG1176	ABC-type spermidine putrescine transport system, permease component I
ArtHe_07500	COG3842	ATPase activity
ArtHe_07535	COG1231	oxidoreductase activity
ArtHe_07540	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ArtHe_07545	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ArtHe_07550	COG1780	Probably involved in ribonucleotide reductase function
ArtHe_07555	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ArtHe_07560	COG0583	DNA-binding transcription factor activity
ArtHe_07585	COG3621	Patatin-like phospholipase
ArtHe_07635	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ArtHe_07645	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ArtHe_07650	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ArtHe_07655	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ArtHe_07660	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ArtHe_07665	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ArtHe_07670	COG1530	ribonuclease E activity
ArtHe_07685	COG0105	UTP biosynthetic process
ArtHe_07695	COG0285	dihydrofolate synthase activity
ArtHe_07700	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ArtHe_07705	COG4221	oxidoreductase activity
ArtHe_07715	COG3189	MarR family transcriptional regulator
ArtHe_07720	COG0525	valine-tRNA ligase activity
ArtHe_07725	COG1957	nucleoside hydrolase
ArtHe_07730	COG0477	Major facilitator Superfamily
ArtHe_07735	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ArtHe_07745	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
ArtHe_07750	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ArtHe_07755	COG0740	serine-type endopeptidase activity
ArtHe_07760	COG0740	serine-type endopeptidase activity
ArtHe_07765	COG0544	peptidyl-prolyl cis-trans isomerase activity
ArtHe_07805	COG0668	transmembrane transport
ArtHe_07820	COG0824	Thioesterase
ArtHe_07825	COG1946	Acyl-CoA thioesterase
ArtHe_07840	COG0629	single-stranded DNA binding
ArtHe_07910	COG0242	peptide deformylase activity
ArtHe_07930	COG3022	response to hydroperoxide
ArtHe_07945	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ArtHe_07950	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ArtHe_07960	COG1045	serine acetyltransferase
ArtHe_07965	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ArtHe_08005	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ArtHe_08020	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ArtHe_08025	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ArtHe_08030	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ArtHe_08050	COG4974	Belongs to the 'phage' integrase family
ArtHe_08070	COG3833	ABC-type maltose transport systems, permease component
ArtHe_08075	COG4948	Mandelate Racemase Muconate Lactonizing
ArtHe_08080	COG1028	Short-chain dehydrogenase reductase Sdr
ArtHe_08100	COG1070	Carbohydrate kinase
ArtHe_08105	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ArtHe_08120	COG0792	nuclease activity
ArtHe_08135	COG3395	kinase activity
ArtHe_08140	COG0235	Class ii aldolase
ArtHe_08145	COG1349	DNA-binding transcription factor activity
ArtHe_08165	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ArtHe_08170	COG0681	Belongs to the peptidase S26 family
ArtHe_08175	COG0681	Belongs to the peptidase S26 family
ArtHe_08180	COG0335	large ribosomal subunit rRNA binding
ArtHe_08185	COG0336	Belongs to the RNA methyltransferase TrmD family
ArtHe_08190	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ArtHe_08195	COG1837	Belongs to the UPF0109 family
ArtHe_08200	COG0228	four-way junction DNA binding
ArtHe_08205	COG2514	catechol 2,3-dioxygenase activity
ArtHe_08250	COG0477	Major facilitator Superfamily
ArtHe_08260	COG1196	nuclear chromosome segregation
ArtHe_08265	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ArtHe_08270	COG0318	PFAM AMP-dependent synthetase and ligase
ArtHe_08275	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ArtHe_08280	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ArtHe_08290	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ArtHe_08295	COG0571	ribonuclease III activity
ArtHe_08300	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ArtHe_08315	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ArtHe_08330	COG0742	ribosomal rna small subunit methyltransferase
ArtHe_08340	COG1461	Dihydroxyacetone kinase
ArtHe_08360	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ArtHe_08370	COG1134	teichoic acid transport
ArtHe_08375	COG1682	transport, permease protein
ArtHe_08380	COG0438	transferase activity, transferring glycosyl groups
ArtHe_08405	COG1181	Belongs to the D-alanine--D-alanine ligase family
ArtHe_08410	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ArtHe_08420	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ArtHe_08425	COG0066	3-isopropylmalate dehydratase activity
ArtHe_08430	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ArtHe_08435	COG1414	Transcriptional regulator
ArtHe_08440	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ArtHe_08470	COG0546	phosphoglycolate phosphatase activity
ArtHe_08475	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ArtHe_08485	COG0179	Fumarylacetoacetate (FAA) hydrolase
ArtHe_08510	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ArtHe_08515	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ArtHe_08520	COG0473	3-isopropylmalate dehydrogenase activity
ArtHe_08525	COG4585	Histidine kinase
ArtHe_08530	COG2197	response regulator
ArtHe_08540	COG0577	efflux transmembrane transporter activity
ArtHe_08540	COG1136	(ABC) transporter
ArtHe_08565	COG1136	(ABC) transporter
ArtHe_08570	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ArtHe_08575	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ArtHe_08580	COG0440	acetolactate synthase activity
ArtHe_08590	COG0129	dihydroxy-acid dehydratase activity
ArtHe_08635	COG0747	negative chemotaxis
ArtHe_08640	COG0601	transmembrane transport
ArtHe_08645	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ArtHe_08655	COG0747	negative chemotaxis
ArtHe_08660	COG0579	oxidoreductase
ArtHe_08665	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ArtHe_08670	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ArtHe_08690	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ArtHe_08710	COG0022	dehydrogenase e1 component
ArtHe_08715	COG0508	dehydrogenase complex catalyzes the overall conversion of
ArtHe_08720	COG0596	Alpha beta hydrolase
ArtHe_08725	COG2815	serine threonine protein kinase
ArtHe_08725	COG0515	serine threonine protein kinase
ArtHe_08735	COG1116	anion transmembrane transporter activity
ArtHe_08740	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ArtHe_08745	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ArtHe_08760	COG0419	ATPase involved in DNA repair
ArtHe_08765	COG0420	3'-5' exonuclease activity
ArtHe_08770	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ArtHe_08785	COG0586	Pfam SNARE associated Golgi protein
ArtHe_08790	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ArtHe_08795	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ArtHe_08805	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ArtHe_08815	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
ArtHe_08825	COG1335	isochorismatase
ArtHe_08850	COG1131	(ABC) transporter
ArtHe_08875	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
ArtHe_08885	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ArtHe_08895	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ArtHe_08900	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ArtHe_08905	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ArtHe_08910	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ArtHe_08915	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ArtHe_08920	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ArtHe_08925	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ArtHe_08930	COG0356	it plays a direct role in the translocation of protons across the membrane
ArtHe_08950	COG1086	Polysaccharide biosynthesis protein
ArtHe_08965	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ArtHe_08970	COG0009	L-threonylcarbamoyladenylate synthase
ArtHe_08975	COG2890	protein-(glutamine-N5) methyltransferase activity
ArtHe_08980	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ArtHe_08990	COG0083	homoserine kinase activity
ArtHe_08995	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ArtHe_09000	COG0460	homoserine dehydrogenase
ArtHe_09010	COG0018	arginyl-trna synthetase
ArtHe_09025	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ArtHe_09040	COG0577	efflux transmembrane transporter activity
ArtHe_09040	COG1136	(ABC) transporter
ArtHe_09045	COG1136	(ABC) transporter
ArtHe_09055	COG0028	Belongs to the TPP enzyme family
ArtHe_09075	COG1643	Atp-dependent helicase
ArtHe_09080	COG0537	adenosine 5'-monophosphoramidase activity
ArtHe_09090	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
ArtHe_09090	COG0321	lipoyl(octanoyl) transferase activity
ArtHe_09100	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ArtHe_09105	COG1121	(ABC) transporter
ArtHe_09120	COG1253	flavin adenine dinucleotide binding
ArtHe_09125	COG0508	dehydrogenase complex catalyzes the overall conversion of
ArtHe_09125	COG0567	Dehydrogenase, E1 component
ArtHe_09135	COG0604	alcohol dehydrogenase
ArtHe_09145	COG1595	DNA-templated transcription, initiation
ArtHe_09155	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ArtHe_09160	COG1162	GTPase activity
ArtHe_09165	COG0483	inositol monophosphate 1-phosphatase activity
ArtHe_09175	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
ArtHe_09180	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
ArtHe_09185	COG0366	Alpha amylase catalytic
ArtHe_09230	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ArtHe_09240	COG2177	Part of the ABC transporter FtsEX involved in
ArtHe_09245	COG2884	Cell division ATP-binding protein ftsE
ArtHe_09250	COG1028	Short-chain dehydrogenase reductase Sdr
ArtHe_09255	COG2755	lipolytic protein G-D-S-L family
ArtHe_09255	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
ArtHe_09260	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ArtHe_09320	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
ArtHe_09325	COG1088	dTDP-glucose 4,6-dehydratase activity
ArtHe_09350	COG0463	Glycosyl transferase, family 2
ArtHe_09385	COG1216	Glycosyl transferase, family 2
ArtHe_09395	COG2755	lipolytic protein G-D-S-L family
ArtHe_09395	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
ArtHe_09420	COG2902	Dehydrogenase
ArtHe_09455	COG0653	protein targeting
ArtHe_09460	COG3214	Protein conserved in bacteria
ArtHe_09465	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ArtHe_09475	COG5401	PFAM Sporulation and spore germination
ArtHe_09480	COG5002	protein histidine kinase activity
ArtHe_09485	COG0745	RESPONSE REGULATOR receiver
ArtHe_09505	COG0714	Associated with various cellular activities
ArtHe_09530	COG0482	sulfurtransferase activity
ArtHe_09540	COG0484	heat shock protein binding
ArtHe_09545	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ArtHe_09555	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ArtHe_09560	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
ArtHe_09570	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ArtHe_09580	COG1842	Phage shock protein A
ArtHe_09595	COG1615	UPF0182 protein
ArtHe_09600	COG3480	Lon protease (S16) C-terminal proteolytic domain
ArtHe_09635	COG0477	Major facilitator Superfamily
ArtHe_09640	COG1846	Transcriptional regulator
ArtHe_09650	COG1131	(ABC) transporter
ArtHe_09660	COG0210	DNA helicase
ArtHe_09680	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ArtHe_09685	COG2011	ABC-type metal ion transport system permease component
ArtHe_09690	COG1464	Belongs to the NlpA lipoprotein family
ArtHe_09695	COG1131	(ABC) transporter
ArtHe_09705	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ArtHe_09710	COG0113	porphobilinogen synthase activity
ArtHe_09720	COG0181	hydroxymethylbilane synthase activity
ArtHe_09725	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ArtHe_09730	COG3253	May function as heme-dependent peroxidase
ArtHe_09735	COG1231	oxidoreductase activity
ArtHe_09740	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ArtHe_09745	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ArtHe_09780	COG0513	Belongs to the DEAD box helicase family
ArtHe_09800	COG0613	PHP domain protein
ArtHe_09805	COG0006	proline dipeptidase activity
ArtHe_09815	COG2239	Acts as a magnesium transporter
ArtHe_09830	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ArtHe_09840	COG1595	DNA-templated transcription, initiation
ArtHe_09850	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ArtHe_09860	COG0519	Catalyzes the synthesis of GMP from XMP
ArtHe_09870	COG1611	Belongs to the LOG family
ArtHe_09875	COG1126	abc transporter atp-binding protein
ArtHe_09880	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ArtHe_09885	COG0765	amino acid transport
ArtHe_09890	COG0765	amino acid transport
ArtHe_09895	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ArtHe_09900	COG2171	N-acyltransferase activity
ArtHe_09910	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ArtHe_09945	COG1217	gtp-binding protein TYPA
ArtHe_09960	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ArtHe_09970	COG4166	transmembrane transport
ArtHe_09995	COG0709	Synthesizes selenophosphate from selenide and ATP
ArtHe_10005	COG0437	4 iron, 4 sulfur cluster binding
ArtHe_10025	COG0384	phenazine biosynthesis protein PhzF
ArtHe_10055	COG0012	GTP binding
ArtHe_10060	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ArtHe_10070	COG1570	exodeoxyribonuclease VII activity
ArtHe_10075	COG1722	exodeoxyribonuclease VII activity
ArtHe_10105	COG0494	nUDIX hydrolase
ArtHe_10110	COG2971	BadF BadG BcrA BcrD
ArtHe_10130	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ArtHe_10135	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ArtHe_10160	COG0519	Catalyzes the synthesis of GMP from XMP
ArtHe_10160	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ArtHe_10180	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ArtHe_10185	COG0516	GMP reductase activity
ArtHe_10195	COG2755	lipolytic protein G-D-S-L family
ArtHe_10195	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
ArtHe_10200	COG0459	protein refolding
ArtHe_10205	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ArtHe_10210	COG4607	ABC-type enterochelin transport system periplasmic component
ArtHe_10215	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ArtHe_10220	COG4605	iron ion homeostasis
ArtHe_10225	COG4604	ABC transporter, ATP-binding protein
ArtHe_10230	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ArtHe_10240	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ArtHe_10245	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
ArtHe_10250	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ArtHe_10260	COG0456	acetyltransferase
ArtHe_10260	COG1214	PFAM Peptidase M22, glycoprotease
ArtHe_10265	COG0802	atpase or kinase
ArtHe_10270	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ArtHe_10280	COG0667	Aldo Keto reductase
ArtHe_10305	COG0736	holo-[acyl-carrier-protein] synthase activity
ArtHe_10315	COG1072	(Pantothenic acid kinase))
ArtHe_10320	COG1970	mechanosensitive ion channel activity
ArtHe_10325	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ArtHe_10330	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ArtHe_10335	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ArtHe_10340	COG0101	tRNA pseudouridine synthase activity
ArtHe_10345	COG0203	ribosomal protein L17
ArtHe_10350	COG0202	RNA polymerase activity
ArtHe_10355	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ArtHe_10360	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ArtHe_10365	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ArtHe_10370	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ArtHe_10380	COG1653	transport
ArtHe_10405	COG0024	Methionine aminopeptidase
ArtHe_10410	COG0563	adenylate kinase activity
ArtHe_10420	COG0200	Binds to the 23S rRNA
ArtHe_10425	COG1841	ribosomal large subunit assembly
ArtHe_10430	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ArtHe_10440	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ArtHe_10445	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ArtHe_10450	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ArtHe_10455	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ArtHe_10460	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ArtHe_10465	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ArtHe_10475	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ArtHe_10480	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ArtHe_10485	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ArtHe_10490	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ArtHe_10495	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ArtHe_10500	COG0089	rRNA binding
ArtHe_10505	COG0088	Forms part of the polypeptide exit tunnel
ArtHe_10510	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ArtHe_10515	COG0051	transcription antitermination factor activity, RNA binding
ArtHe_10525	COG0318	PFAM AMP-dependent synthetase and ligase
ArtHe_10530	COG1960	acyl-CoA dehydrogenase activity
ArtHe_10535	COG0446	pyridine nucleotide-disulphide oxidoreductase
ArtHe_10535	COG1902	pentaerythritol trinitrate reductase activity
ArtHe_10540	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ArtHe_10545	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ArtHe_10550	COG0049	tRNA binding
ArtHe_10555	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ArtHe_10560	COG1414	Transcriptional regulator
ArtHe_10565	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ArtHe_10575	COG0183	Belongs to the thiolase family
ArtHe_10580	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ArtHe_10585	COG0508	dehydrogenase complex catalyzes the overall conversion of
ArtHe_10585	COG0596	Alpha beta hydrolase
ArtHe_10595	COG3485	protocatechuate 3,4-dioxygenase
ArtHe_10600	COG3485	protocatechuate 3,4-dioxygenase
ArtHe_10615	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ArtHe_10620	COG0085	RNA polymerase activity
ArtHe_10625	COG0183	Belongs to the thiolase family
ArtHe_10630	COG0442	prolyl-tRNA aminoacylation
ArtHe_10635	COG0222	ribosome binding
ArtHe_10640	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ArtHe_10650	COG2610	gluconate transmembrane transporter activity
ArtHe_10655	COG2084	Dehydrogenase
ArtHe_10675	COG0081	regulation of translation
ArtHe_10680	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ArtHe_10700	COG0436	Aminotransferase
ArtHe_10705	COG2197	response regulator
ArtHe_10750	COG3485	protocatechuate 3,4-dioxygenase
ArtHe_10760	COG0745	RESPONSE REGULATOR receiver
ArtHe_10765	COG0456	acetyltransferase
ArtHe_10770	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ArtHe_10780	COG1528	Iron-storage protein
ArtHe_10795	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ArtHe_10800	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ArtHe_10805	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ArtHe_10810	COG2814	Major facilitator Superfamily
ArtHe_10815	COG1846	Transcriptional regulator
ArtHe_10820	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ArtHe_10830	COG2030	dehydratase
ArtHe_10860	COG0693	protein deglycase activity
ArtHe_10880	COG0515	serine threonine protein kinase
ArtHe_10895	COG2258	MOSC domain
ArtHe_10930	COG2351	hydroxyisourate hydrolase activity
ArtHe_10935	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ArtHe_10945	COG2233	PERMEase
ArtHe_10950	COG1414	Transcriptional regulator
ArtHe_10965	COG3257	ureidoglycine aminohydrolase activity
ArtHe_10970	COG3622	Belongs to the hyi family
ArtHe_10975	COG2084	Dehydrogenase
ArtHe_10980	COG3960	tartronate-semialdehyde synthase activity
ArtHe_10985	COG1929	Belongs to the glycerate kinase type-1 family
ArtHe_11005	COG1063	alcohol dehydrogenase
ArtHe_11010	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ArtHe_11030	COG1666	GTP binding
ArtHe_11040	COG0501	Belongs to the peptidase M48B family
ArtHe_11055	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
ArtHe_11065	COG2267	carboxylic ester hydrolase activity
ArtHe_11095	COG1233	COG1233 Phytoene dehydrogenase and related
ArtHe_11105	COG0142	geranyltranstransferase activity
ArtHe_11110	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
ArtHe_11190	COG0477	Major facilitator Superfamily
ArtHe_11195	COG0583	DNA-binding transcription factor activity
ArtHe_11240	COG0142	geranyltranstransferase activity
ArtHe_11250	COG2226	methyltransferase
ArtHe_11260	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ArtHe_11265	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ArtHe_11270	COG0765	amino acid transport
ArtHe_11280	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
ArtHe_11285	COG4948	Mandelate Racemase Muconate Lactonizing
ArtHe_11305	COG0508	dehydrogenase complex catalyzes the overall conversion of
ArtHe_11310	COG0022	dehydrogenase e1 component
ArtHe_11330	COG2837	iron assimilation
ArtHe_11340	COG2372	response to copper ion
ArtHe_11350	COG1024	Enoyl-CoA hydratase
ArtHe_11355	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ArtHe_11360	COG2151	metal-sulfur cluster biosynthetic enzyme
ArtHe_11365	COG3396	Phenylacetate-CoA oxygenase
ArtHe_11370	COG3460	Phenylacetate-CoA oxygenase
ArtHe_11375	COG3396	Phenylacetate-CoA oxygenase
ArtHe_11390	COG0586	Pfam SNARE associated Golgi protein
ArtHe_11395	COG2050	protein possibly involved in aromatic compounds catabolism
ArtHe_11410	COG2030	dehydratase
ArtHe_11410	COG1012	belongs to the aldehyde dehydrogenase family
ArtHe_11420	COG1063	alcohol dehydrogenase
ArtHe_11430	COG2365	Tyrosine phosphatase family
ArtHe_11435	COG1250	3-hydroxyacyl-CoA dehydrogenase
ArtHe_11440	COG1024	Enoyl-CoA hydratase
ArtHe_11480	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ArtHe_11505	COG1140	nitrate reductase beta subunit
ArtHe_11515	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
ArtHe_11530	COG2197	response regulator
ArtHe_11555	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ArtHe_11565	COG0785	Cytochrome C biogenesis protein
ArtHe_11575	COG0406	alpha-ribazole phosphatase activity
ArtHe_11580	COG2353	YceI-like domain
ArtHe_11595	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
ArtHe_11620	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ArtHe_11630	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ArtHe_11635	COG0640	Transcriptional regulator
ArtHe_11640	COG0123	including yeast histone deacetylase and acetoin utilization protein
ArtHe_11645	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ArtHe_11650	COG0569	domain protein
ArtHe_11655	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ArtHe_11660	COG1082	Xylose isomerase domain protein TIM barrel
ArtHe_11665	COG0248	Ppx GppA phosphatase
ArtHe_11670	COG1754	DNA topoisomerase type I activity
ArtHe_11670	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ArtHe_11675	COG2890	protein-(glutamine-N5) methyltransferase activity
ArtHe_11680	COG2814	Major facilitator Superfamily
ArtHe_11690	COG1054	Belongs to the UPF0176 family
ArtHe_11700	COG1111	helicase
ArtHe_11700	COG1205	dead DEAH box helicase
ArtHe_11710	COG1070	Carbohydrate kinase
ArtHe_11715	COG2390	Transcriptional regulator
ArtHe_11720	COG1063	alcohol dehydrogenase
ArtHe_11725	COG1129	ABC transporter
ArtHe_11730	COG1172	Belongs to the binding-protein-dependent transport system permease family
ArtHe_11735	COG1879	ABC-type sugar transport system periplasmic component
ArtHe_11795	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ArtHe_11805	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ArtHe_11810	COG1764	response to oxidative stress
ArtHe_11820	COG0477	Major facilitator Superfamily
ArtHe_11845	COG0251	oxidation-reduction process
ArtHe_11855	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ArtHe_11865	COG1132	(ABC) transporter
ArtHe_11870	COG1132	(ABC) transporter
ArtHe_11880	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ArtHe_11880	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ArtHe_11885	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ArtHe_11890	COG0151	Belongs to the GarS family
ArtHe_11915	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ArtHe_11940	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ArtHe_11945	COG1012	belongs to the aldehyde dehydrogenase family
ArtHe_11955	COG0768	penicillin binding
ArtHe_11960	COG0768	penicillin binding
ArtHe_11965	COG3304	Inner membrane component domain
ArtHe_11995	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ArtHe_12015	COG1131	(ABC) transporter
ArtHe_12025	COG0789	Transcriptional regulator
ArtHe_12030	COG0484	heat shock protein binding
ArtHe_12035	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ArtHe_12040	COG0443	Heat shock 70 kDa protein
ArtHe_12045	COG2226	methyltransferase
ArtHe_12050	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ArtHe_12060	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ArtHe_12075	COG1122	ATPase activity
ArtHe_12080	COG4721	ABC-type cobalt transport system, permease component
ArtHe_12095	COG2212	antiporter activity
ArtHe_12105	COG0651	ATP synthesis coupled electron transport
ArtHe_12115	COG2111	Na H antiporter
ArtHe_12115	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ArtHe_12125	COG0717	Belongs to the dCTP deaminase family
ArtHe_12130	COG3483	tryptophan 2,3-dioxygenase activity
ArtHe_12155	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
ArtHe_12195	COG0776	regulation of translation
ArtHe_12200	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ArtHe_12205	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ArtHe_12210	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ArtHe_12215	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ArtHe_12225	COG0477	Major facilitator Superfamily
ArtHe_12235	COG1597	lipid kinase activity
ArtHe_12235	COG1803	Methylglyoxal synthase
ArtHe_12240	COG1196	nuclear chromosome segregation
ArtHe_12240	COG0741	lytic transglycosylase activity
ArtHe_12240	COG0739	heme binding
ArtHe_12245	COG0596	Alpha beta hydrolase
ArtHe_12250	COG3321	synthase
ArtHe_12250	COG0604	alcohol dehydrogenase
ArtHe_12265	COG1120	ATPase activity
ArtHe_12270	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ArtHe_12275	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ArtHe_12280	COG0435	Glutathione S-transferase
ArtHe_12295	COG1295	ribonuclease BN
ArtHe_12315	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ArtHe_12350	COG1028	Short-chain dehydrogenase reductase Sdr
ArtHe_12370	COG3048	D-serine ammonia-lyase activity
ArtHe_12390	COG2813	Specifically methylates the guanine in position
ArtHe_12395	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ArtHe_12410	COG0531	amino acid
ArtHe_12420	COG1473	amidohydrolase
ArtHe_12425	COG4585	Histidine kinase
ArtHe_12430	COG2197	response regulator
ArtHe_12435	COG4152	abc transporter atp-binding protein
ArtHe_12445	COG5006	permease, DMT superfamily
ArtHe_12475	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ArtHe_12480	COG1414	Transcriptional regulator
ArtHe_12490	COG3257	ureidoglycine aminohydrolase activity
ArtHe_12495	COG3622	Belongs to the hyi family
ArtHe_12500	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ArtHe_12505	COG1285	pathogenesis
ArtHe_12510	COG0647	UMP catabolic process
ArtHe_12515	COG0395	ABC-type sugar transport system, permease component
ArtHe_12520	COG4209	transmembrane transport
ArtHe_12535	COG1609	Transcriptional regulator
ArtHe_12575	COG0028	Belongs to the TPP enzyme family
ArtHe_12580	COG0583	DNA-binding transcription factor activity
ArtHe_12600	COG1028	Short-chain dehydrogenase reductase Sdr
ArtHe_12625	COG1028	Short-chain dehydrogenase reductase Sdr
ArtHe_12630	COG1024	Enoyl-CoA hydratase
ArtHe_12640	COG1028	Short-chain dehydrogenase reductase Sdr
ArtHe_12645	COG1012	belongs to the aldehyde dehydrogenase family
ArtHe_12665	COG0318	PFAM AMP-dependent synthetase and ligase
ArtHe_12680	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
ArtHe_12685	COG1473	amidohydrolase
ArtHe_12690	COG4221	oxidoreductase activity
ArtHe_12710	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
ArtHe_12715	COG1984	allophanate hydrolase subunit 2
ArtHe_12720	COG0028	Belongs to the TPP enzyme family
ArtHe_12735	COG1129	ABC transporter
ArtHe_12750	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ArtHe_12775	COG0596	Alpha beta hydrolase
ArtHe_12780	COG5002	protein histidine kinase activity
ArtHe_12800	COG2814	Major facilitator Superfamily
ArtHe_12805	COG3254	rhamnose metabolic process
ArtHe_12810	COG4952	isomerase
ArtHe_12815	COG1028	Short-chain dehydrogenase reductase Sdr
ArtHe_12815	COG3347	Dehydrogenase
ArtHe_12820	COG1070	Carbohydrate kinase
ArtHe_12825	COG1609	Transcriptional regulator
ArtHe_12855	COG3842	ATPase activity
ArtHe_12860	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ArtHe_12865	COG1176	ABC-type spermidine putrescine transport system, permease component I
ArtHe_12870	COG1177	transmembrane transport
ArtHe_12895	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
ArtHe_12900	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ArtHe_12905	COG0366	Alpha amylase catalytic
ArtHe_12915	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
ArtHe_12920	COG3639	organic phosphonate transmembrane transporter activity
ArtHe_12935	COG0656	L-ascorbic acid biosynthetic process
ArtHe_12975	COG2197	response regulator
ArtHe_12980	COG4585	Histidine kinase
ArtHe_12990	COG1136	(ABC) transporter
ArtHe_13015	COG4592	Periplasmic binding protein
ArtHe_13020	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ArtHe_13025	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ArtHe_13030	COG1120	ATPase activity
ArtHe_13040	COG2382	esterase
ArtHe_13050	COG1846	Transcriptional regulator
ArtHe_13060	COG2807	transmembrane transport
ArtHe_13105	COG0583	DNA-binding transcription factor activity
ArtHe_13125	COG0477	Major facilitator Superfamily
ArtHe_13150	COG2855	membrane
ArtHe_13170	COG2124	cytochrome p450
ArtHe_13175	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ArtHe_13180	COG1414	Transcriptional regulator
ArtHe_13200	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ArtHe_13225	COG0277	FAD linked oxidase domain protein
ArtHe_13240	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ArtHe_13250	COG1902	pentaerythritol trinitrate reductase activity
ArtHe_13255	COG0640	Transcriptional regulator
ArtHe_13260	COG2076	Multidrug Resistance protein
ArtHe_13265	COG2076	Multidrug Resistance protein
ArtHe_13270	COG0531	amino acid
ArtHe_13275	COG2205	protein histidine kinase activity
ArtHe_13280	COG0745	RESPONSE REGULATOR receiver
ArtHe_13320	COG0492	ferredoxin-NADP+ reductase activity
ArtHe_13390	COG1121	(ABC) transporter
ArtHe_13395	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ArtHe_13415	COG1120	ATPase activity
ArtHe_13425	COG1070	Carbohydrate kinase
ArtHe_13435	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ArtHe_13465	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ArtHe_13510	COG1902	pentaerythritol trinitrate reductase activity
ArtHe_13515	COG2252	PERMEase
ArtHe_13525	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ArtHe_13545	COG1120	ATPase activity
ArtHe_13550	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ArtHe_13575	COG2267	carboxylic ester hydrolase activity
ArtHe_13590	COG0656	L-ascorbic acid biosynthetic process
ArtHe_13595	COG1028	Short-chain dehydrogenase reductase Sdr
ArtHe_13600	COG1053	succinate dehydrogenase
ArtHe_13605	COG0477	Major facilitator Superfamily
ArtHe_13615	COG1053	succinate dehydrogenase
ArtHe_13620	COG1414	Transcriptional regulator
ArtHe_13660	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
ArtHe_13665	COG2116	formate transmembrane transporter activity
ArtHe_13695	COG0415	Belongs to the DNA photolyase family
ArtHe_13700	COG0515	serine threonine protein kinase
ArtHe_13715	COG0488	(ABC) transporter
ArtHe_13780	COG1802	Transcriptional regulator
ArtHe_13810	COG1063	alcohol dehydrogenase
ArtHe_13845	COG0598	Magnesium transport protein CorA
ArtHe_13855	COG2807	transmembrane transport
ArtHe_13890	COG1028	Short-chain dehydrogenase reductase Sdr
ArtHe_13895	COG2814	Major facilitator Superfamily
ArtHe_13905	COG0477	Major facilitator Superfamily
ArtHe_13930	COG2233	PERMEase
ArtHe_13965	COG2409	Drug exporters of the RND superfamily
ArtHe_13985	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ArtHe_13990	COG0277	FAD linked oxidase domain protein
ArtHe_13995	COG1620	l-lactate permease
ArtHe_14000	COG1028	Short-chain dehydrogenase reductase Sdr
ArtHe_14020	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ArtHe_14025	COG0509	glycine decarboxylation via glycine cleavage system
ArtHe_14030	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ArtHe_14035	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ArtHe_14035	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ArtHe_14040	COG1113	amino acid transport
ArtHe_14045	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ArtHe_14070	COG1302	Protein conserved in bacteria
ArtHe_14080	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ArtHe_14095	COG0686	Belongs to the AlaDH PNT family
ArtHe_14105	COG0673	inositol 2-dehydrogenase activity
ArtHe_14140	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ArtHe_14150	COG0508	dehydrogenase complex catalyzes the overall conversion of
ArtHe_14155	COG0022	dehydrogenase e1 component
ArtHe_14165	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ArtHe_14170	COG1950	PFAM Membrane protein of
ArtHe_14185	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ArtHe_14190	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ArtHe_14195	COG0590	tRNA wobble adenosine to inosine editing
ArtHe_14205	COG2807	transmembrane transport
ArtHe_14210	COG1234	tRNA 3'-trailer cleavage
ArtHe_14215	COG0477	Major facilitator Superfamily
ArtHe_14220	COG0583	DNA-binding transcription factor activity
ArtHe_14245	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ArtHe_14270	COG2814	Major facilitator Superfamily
ArtHe_14275	COG2124	cytochrome p450
ArtHe_14290	COG1309	transcriptional regulator
ArtHe_14295	COG0387	Pfam Sodium calcium exchanger
ArtHe_14310	COG1012	belongs to the aldehyde dehydrogenase family
ArtHe_14335	COG3226	Transcriptional regulator
ArtHe_14375	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ArtHe_14380	COG1595	DNA-templated transcription, initiation
ArtHe_14385	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ArtHe_14390	COG1960	acyl-CoA dehydrogenase activity
ArtHe_14400	COG1028	Short-chain dehydrogenase reductase Sdr
ArtHe_14420	COG0659	secondary active sulfate transmembrane transporter activity
ArtHe_14430	COG2515	1-aminocyclopropane-1-carboxylate deaminase
ArtHe_14440	COG0514	ATP-dependent DNA helicase (RecQ)
ArtHe_14470	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ArtHe_14475	COG1216	Glycosyl transferase, family 2
ArtHe_14485	COG3546	catalase activity
ArtHe_14490	COG0019	diaminopimelate decarboxylase activity
ArtHe_14495	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
ArtHe_14505	COG2197	response regulator
ArtHe_14515	COG0444	Belongs to the ABC transporter superfamily
ArtHe_14520	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ArtHe_14545	COG0318	PFAM AMP-dependent synthetase and ligase
ArtHe_14555	COG0697	spore germination
ArtHe_14590	COG0534	Mate efflux family protein
ArtHe_14595	COG2814	Major facilitator Superfamily
ArtHe_14615	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
ArtHe_14620	COG1652	LysM domain
ArtHe_14625	COG0531	amino acid
ArtHe_14630	COG0488	(ABC) transporter
ArtHe_14640	COG0305	Participates in initiation and elongation during chromosome replication
ArtHe_14645	COG0359	binds to the 23S rRNA
ArtHe_14650	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ArtHe_14660	COG0360	Binds together with S18 to 16S ribosomal RNA
ArtHe_14665	COG1362	aminopeptidase activity
ArtHe_14675	COG1131	(ABC) transporter
ArtHe_14685	COG1131	(ABC) transporter
ArtHe_14700	COG0738	Major facilitator superfamily
ArtHe_14705	COG0488	(ABC) transporter
ArtHe_14740	COG1522	sequence-specific DNA binding
ArtHe_14760	COG2759	Belongs to the formate--tetrahydrofolate ligase family
ArtHe_14765	COG0438	transferase activity, transferring glycosyl groups
ArtHe_14775	COG0406	alpha-ribazole phosphatase activity
ArtHe_14780	COG0617	tRNA 3'-terminal CCA addition
ArtHe_14800	COG0492	ferredoxin-NADP+ reductase activity
ArtHe_14805	COG3118	belongs to the thioredoxin family
ArtHe_14810	COG0860	N-Acetylmuramoyl-L-alanine amidase
ArtHe_14810	COG3409	Peptidoglycan-binding domain 1 protein
ArtHe_14835	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ArtHe_14840	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ArtHe_14850	COG1475	DNA binding
ArtHe_14855	COG1192	Involved in chromosome partitioning
ArtHe_14860	COG0357	Ribosomal RNA small subunit methyltransferase G
ArtHe_14870	COG0706	membrane insertase activity
ArtHe_14875	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ArtHe_14880	COG0594	ribonuclease P activity
ArtHe_14885	COG0230	Belongs to the bacterial ribosomal protein bL34 family
ArtHe_14890	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ArtHe_14900	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
ArtHe_14905	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ArtHe_14910	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
ArtHe_14915	COG0187	DNA topoisomerase II activity
ArtHe_14920	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ArtHe_14960	COG0705	Rhomboid family
ArtHe_14970	COG3764	Sortase (surface protein transpeptidase)
ArtHe_14985	COG0515	serine threonine protein kinase
ArtHe_14985	COG2815	serine threonine protein kinase
ArtHe_14990	COG0515	serine threonine protein kinase
ArtHe_14995	COG0768	penicillin binding
ArtHe_15010	COG1716	ATPase activity
ArtHe_15040	COG3265	gluconokinase activity
ArtHe_15045	COG2186	Transcriptional regulator
ArtHe_15050	COG0783	Belongs to the Dps family
ArtHe_15080	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ArtHe_15100	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
ArtHe_15135	COG0110	maltose O-acetyltransferase activity
ArtHe_15155	COG1376	ErfK ybiS ycfS ynhG family protein
ArtHe_15160	COG0702	epimerase
ArtHe_15180	COG1028	Short-chain dehydrogenase reductase Sdr
ArtHe_15210	COG0671	phosphoesterase, PA-phosphatase related
ArtHe_15215	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
ArtHe_15225	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
ArtHe_15235	COG1929	Belongs to the glycerate kinase type-1 family
ArtHe_15245	COG2233	PERMEase
ArtHe_15250	COG0300	oxidoreductase activity
ArtHe_15255	COG1012	belongs to the aldehyde dehydrogenase family
ArtHe_15260	COG0033	Phosphoglucomutase
ArtHe_15265	COG1116	anion transmembrane transporter activity
ArtHe_15265	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ArtHe_15280	COG3104	oligopeptide transport
ArtHe_15285	COG0154	amidase activity
ArtHe_15290	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ArtHe_15310	COG1597	lipid kinase activity
ArtHe_15315	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ArtHe_15320	COG0561	phosphatase activity
ArtHe_15330	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ArtHe_15335	COG2027	D-alanyl-D-alanine carboxypeptidase
ArtHe_15345	COG0037	tRNA processing
ArtHe_15355	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ArtHe_15360	COG0302	gtp cyclohydrolase
ArtHe_15370	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ArtHe_15400	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ArtHe_15405	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ArtHe_15425	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
ArtHe_15435	COG2376	Dihydroxyacetone kinase
ArtHe_15440	COG1461	Dihydroxyacetone kinase
ArtHe_15460	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
ArtHe_15490	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ArtHe_15495	COG0306	phosphate transporter
ArtHe_15525	COG1937	Protein conserved in bacteria
ArtHe_15560	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ArtHe_15560	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ArtHe_15565	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ArtHe_15570	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ArtHe_15570	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ArtHe_15570	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ArtHe_15585	COG2261	transglycosylase associated protein
ArtHe_15595	COG2733	membrane
ArtHe_15605	COG3387	PFAM Glycoside hydrolase 15-related
ArtHe_15625	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ArtHe_15630	COG0857	belongs to the CobB CobQ family
ArtHe_15630	COG0280	phosphate acetyltransferase
ArtHe_15635	COG0531	amino acid
ArtHe_15645	COG4122	O-methyltransferase activity
ArtHe_15655	COG2252	PERMEase
ArtHe_15735	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ArtHe_15740	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ArtHe_15760	COG0191	fructose-bisphosphate aldolase activity
ArtHe_15785	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ArtHe_15805	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ArtHe_15825	COG1832	CoA-binding protein
ArtHe_15840	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ArtHe_15845	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ArtHe_15855	COG1116	anion transmembrane transporter activity
ArtHe_15875	COG0277	FAD linked oxidase domain protein
ArtHe_15880	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ArtHe_15885	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ArtHe_15900	COG1028	Short-chain dehydrogenase reductase Sdr
ArtHe_15910	COG0477	Major facilitator Superfamily
ArtHe_15915	COG1234	tRNA 3'-trailer cleavage
ArtHe_15945	COG2076	Multidrug Resistance protein
ArtHe_15950	COG2076	Multidrug Resistance protein
ArtHe_15955	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ArtHe_15960	COG2011	ABC-type metal ion transport system permease component
ArtHe_15985	COG2315	Protein conserved in bacteria
ArtHe_16015	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ArtHe_16020	COG0047	phosphoribosylformylglycinamidine synthase activity
ArtHe_16025	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ArtHe_16050	COG1846	Transcriptional regulator
ArtHe_16085	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ArtHe_16125	COG3548	integral membrane protein
ArtHe_16140	COG0318	PFAM AMP-dependent synthetase and ligase
ArtHe_16145	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ArtHe_16150	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ArtHe_16150	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ArtHe_16220	COG0765	amino acid transport
ArtHe_16240	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ArtHe_16260	COG0745	RESPONSE REGULATOR receiver
ArtHe_16265	COG2205	protein histidine kinase activity
ArtHe_16305	COG0531	amino acid
ArtHe_16345	COG0477	Major facilitator Superfamily
ArtHe_16405	COG2200	EAL domain
ArtHe_16420	COG1063	alcohol dehydrogenase
ArtHe_16455	COG0534	Mate efflux family protein
ArtHe_16480	COG1063	alcohol dehydrogenase
ArtHe_16485	COG1737	Transcriptional regulator
ArtHe_16500	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ArtHe_16505	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
ArtHe_16510	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
ArtHe_16540	COG0531	amino acid
ArtHe_16545	COG0477	Major facilitator Superfamily
ArtHe_16555	COG0583	DNA-binding transcription factor activity
ArtHe_16560	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
ArtHe_16570	COG0765	amino acid transport
ArtHe_16580	COG0583	DNA-binding transcription factor activity
ArtHe_16590	COG0657	acetylesterase activity
ArtHe_16615	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ArtHe_16620	COG0657	acetylesterase activity
ArtHe_16625	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
ArtHe_16630	COG1940	carbohydrate kinase activity
ArtHe_16635	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ArtHe_16640	COG4608	Belongs to the ABC transporter superfamily
ArtHe_16645	COG0444	Belongs to the ABC transporter superfamily
ArtHe_16655	COG0747	negative chemotaxis
ArtHe_16660	COG2186	Transcriptional regulator
ArtHe_16665	COG0363	glucosamine-6-phosphate deaminase activity
ArtHe_16720	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ArtHe_16750	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ArtHe_16775	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ArtHe_16785	COG0179	Fumarylacetoacetate (FAA) hydrolase
ArtHe_16795	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ArtHe_16805	COG0179	Fumarylacetoacetate (FAA) hydrolase
ArtHe_16815	COG2814	Major facilitator Superfamily
ArtHe_16830	COG1172	Belongs to the binding-protein-dependent transport system permease family
ArtHe_16835	COG1129	ABC transporter
ArtHe_16850	COG0351	phosphomethylpyrimidine kinase
ArtHe_16870	COG0343	queuine tRNA-ribosyltransferase activity
ArtHe_16940	COG3486	L-lysine 6-monooxygenase (NADPH) activity
ArtHe_16945	COG0076	glutamate decarboxylase activity
ArtHe_16965	COG0564	pseudouridine synthase activity
ArtHe_16975	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ArtHe_16980	COG1201	RNA secondary structure unwinding
ArtHe_16995	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ArtHe_17000	COG1120	ATPase activity
ArtHe_17005	COG0596	Alpha beta hydrolase
ArtHe_17015	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ArtHe_17030	COG2354	Protein conserved in bacteria
ArtHe_17065	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ArtHe_17075	COG2062	phosphohistidine phosphatase, SixA
ArtHe_17090	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
ArtHe_17110	COG1053	succinate dehydrogenase
ArtHe_17115	COG0656	L-ascorbic acid biosynthetic process
ArtHe_17130	COG0673	inositol 2-dehydrogenase activity
ArtHe_17135	COG0477	Major facilitator Superfamily
ArtHe_17155	COG4948	Mandelate Racemase Muconate Lactonizing
ArtHe_17180	COG1172	Belongs to the binding-protein-dependent transport system permease family
ArtHe_17190	COG1012	belongs to the aldehyde dehydrogenase family
ArtHe_17195	COG0028	Belongs to the TPP enzyme family
ArtHe_17210	COG0477	Major facilitator Superfamily
ArtHe_17225	COG1136	(ABC) transporter
ArtHe_17240	COG0745	RESPONSE REGULATOR receiver
ArtHe_17245	COG2205	protein histidine kinase activity
ArtHe_17250	COG1024	Enoyl-CoA hydratase
ArtHe_17260	COG0667	Aldo Keto reductase
ArtHe_17265	COG0579	oxidoreductase
ArtHe_17270	COG2239	Acts as a magnesium transporter
ArtHe_17280	COG1505	serine-type exopeptidase activity
ArtHe_17300	COG2860	membrane
ArtHe_17350	COG0351	phosphomethylpyrimidine kinase
ArtHe_17350	COG0352	thiamine-phosphate diphosphorylase activity
ArtHe_17350	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
ArtHe_17355	COG0352	thiamine-phosphate diphosphorylase activity
ArtHe_17360	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
ArtHe_17380	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
ArtHe_17385	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
ArtHe_17390	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
ArtHe_17420	COG2259	Doxx family
ArtHe_17430	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
ArtHe_17445	COG1228	amidohydrolase
ArtHe_17450	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ArtHe_17475	COG0604	alcohol dehydrogenase
ArtHe_17475	COG1028	Short-chain dehydrogenase reductase Sdr
ArtHe_17475	COG3321	synthase
ArtHe_17480	COG1966	Carbon starvation protein
ArtHe_17505	COG0656	L-ascorbic acid biosynthetic process
ArtHe_17510	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
ArtHe_17515	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ArtHe_17520	COG1256	bacterial-type flagellum assembly
ArtHe_17520	COG4786	Flagellar basal body rod
ArtHe_17535	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ArtHe_17545	COG1516	flagellar protein fliS
ArtHe_17555	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ArtHe_17565	COG1558	bacterial-type flagellum-dependent cell motility
ArtHe_17570	COG1677	Flagellar hook-basal body complex protein FliE
ArtHe_17575	COG1766	The M ring may be actively involved in energy transduction
ArtHe_17580	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ArtHe_17590	COG1157	protein secretion by the type III secretion system
ArtHe_17610	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
ArtHe_17625	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ArtHe_17630	COG1360	Flagellar Motor Protein
ArtHe_17640	COG1776	CheC inhibitor of MCP methylation
ArtHe_17640	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ArtHe_17650	COG1338	Plays a role in the flagellum-specific transport system
ArtHe_17665	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ArtHe_17670	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ArtHe_17680	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ArtHe_17710	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ArtHe_17715	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ArtHe_17720	COG0626	cystathionine gamma-synthase activity
ArtHe_17735	COG0588	phosphoglycerate mutase activity
ArtHe_17745	COG5002	protein histidine kinase activity
ArtHe_17750	COG0745	RESPONSE REGULATOR receiver
ArtHe_17765	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ArtHe_17770	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ArtHe_17775	COG0215	cysteine-tRNA ligase activity
ArtHe_17780	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ArtHe_17795	COG0366	Alpha amylase catalytic
ArtHe_17805	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position