locus-tag	class	description
UM93_00020	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
UM93_00025	ENOG4105BZU	Histidine kinase
UM93_00030	ENOG4105WH1	Two component transcriptional regulator luxr family
UM93_00035	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
UM93_00085	ENOG4105KBX	Transcriptional regulator, TetR family
UM93_00090	ENOG4105EYF	MMPL domain protein
UM93_00120	ENOG4105CJ1	ABC, transporter
UM93_00150	ENOG4105CPF	Cell wall formation (By similarity)
UM93_00160	ENOG4105CPU	Monooxygenase
UM93_00185	ENOG4105BZN	citrate synthase
UM93_00205	ENOG4105WH1	Two component transcriptional regulator luxr family
UM93_00220	ENOG4105IIP	Membrane
UM93_00235	ENOG4105C31	Tryptophanyl-tRNA synthetase
UM93_00260	ENOG4105E33	succinate dehydrogenase
UM93_00285	ENOG4107RM1	amidohydrolase
UM93_00290	ENOG4105K56	Transcriptional regulator
UM93_00295	ENOG4108ZHJ	Organic hydroperoxide resistance protein
UM93_00300	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
UM93_00305	ENOG4105DEN	Luciferase family
UM93_00310	ENOG4105DIH	basic membrane
UM93_00315	ENOG4108JQ9	ABC transporter
UM93_00320	ENOG4105UIB	(ABC) transporter
UM93_00355	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
UM93_00375	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
UM93_00395	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
UM93_00415	ENOG4108Z4X	TRANSCRIPTIONal
UM93_00420	ENOG4108PSK	reductase
UM93_00430	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
UM93_00445	ENOG4105C7B	Threonine dehydratase
UM93_00450	ENOG4107YD5	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
UM93_00460	ENOG4105T1M	mycothiol conjugate amidase mca
UM93_00470	ENOG4108UT2	hemolysin iii
UM93_00475	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
UM93_00480	ENOG4108IAB	Phoh family
UM93_00510	ENOG4105C9Q	fumarate hydratase class II
UM93_00545	ENOG4105EIP	mannose-6-phosphate isomerase
UM93_00550	ENOG4108KGH	TRANSCRIPTIONal
UM93_00555	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
UM93_00575	ENOG4105K51	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
UM93_00605	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
UM93_00660	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
UM93_00665	ENOG4105F8V	Hydrolase, tatD family
UM93_00670	ENOG4106839	domain protein
UM93_00675	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
UM93_00680	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
UM93_00685	ENOG4105C5H	ABC transporter
UM93_00695	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
UM93_00700	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
UM93_00705	ENOG4107XT7	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
UM93_00710	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
UM93_00725	ENOG4108UNV	SUF system FeS assembly protein, NifU family
UM93_00735	ENOG4105C26	Dehydrogenase
UM93_00740	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
UM93_00775	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
UM93_00815	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
UM93_00820	ENOG4107QSU	Phosphoglucomutase phosphomannomutase alpha beta alpha domain
UM93_00835	ENOG4105CSH	Transporter
UM93_00840	ENOG4108JIK	carboxylase
UM93_00850	ENOG4105C26	Dehydrogenase
UM93_00855	ENOG4107RR1	TRANSCRIPTIONal
UM93_00860	ENOG4107WR6	Maf-like protein
UM93_00865	ENOG41082VC	UPF0145 protein
UM93_00880	ENOG4105D8K	carboxyl transferase
UM93_00885	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
UM93_00890	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
UM93_00910	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
UM93_00960	ENOG4105EC2	ftsk spoIIIe
UM93_01010	ENOG4105CAQ	asparagine synthetase
UM93_01020	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
UM93_01035	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
UM93_01100	ENOG4105CJ1	ABC, transporter
UM93_01125	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
UM93_01135	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
UM93_01145	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
UM93_01150	ENOG4108CHM	Preferentially cleaves peptide bonds on the carboxyl- terminal side of aspartate and glutamate. Along with other extracellular proteases it is involved in colonization and infection of human tissues. Required for proteolytic maturation of thiol protease SspB and inactivation of SspC, an inhibitor of SspB. It is the most important protease for degradation of fibronectin-binding protein (FnBP) and surface protein A, which are involved in adherence to host cells. May also protect bacteria against host defense mechanism by cleaving the immunoglobulin classes IgG, IgA and IgM. May be involved in the stability of secreted lipases
UM93_01170	ENOG4105FF5	Membrane
UM93_01190	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
UM93_01245	ENOG4105C1G	acyl-Coa dehydrogenase
UM93_01255	ENOG4105CE9	30S ribosomal protein S2
UM93_01260	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
UM93_01265	ENOG4105JAB	phenazine biosynthesis protein, phzf family
UM93_01290	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
UM93_01295	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
UM93_01310	ENOG4107QN1	sodium solute
UM93_01320	ENOG4108NEV	two component transcriptional regulator, LytTR family
UM93_01325	ENOG4108HRK	Histidine kinase
UM93_01335	ENOG4107QN1	sodium solute
UM93_01360	ENOG4105CPP	Dehydrogenase, E1 component
UM93_01365	ENOG4107RN0	branched-chain alpha-keto acid dehydrogenase subunit E2
UM93_01370	ENOG41067SE	Tetr family transcriptional regulator
UM93_01375	ENOG4107QX3	carboxylase
UM93_01385	ENOG4105C1G	acyl-Coa dehydrogenase
UM93_01415	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
UM93_01420	ENOG4105DZP	Membrane-associated zinc metalloprotease
UM93_01440	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
UM93_01450	ENOG4106HB6	Alpha beta hydrolase
UM93_01485	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
UM93_01520	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
UM93_01525	ENOG4107ZPY	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
UM93_01530	ENOG4105CHM	Aminotransferase
UM93_01535	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
UM93_01555	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
UM93_01570	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
UM93_01575	ENOG4105ECQ	AraC Family Transcriptional Regulator
UM93_01580	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
UM93_01585	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
UM93_01590	ENOG4105C1V	Peptidase, M16
UM93_01665	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
UM93_01675	ENOG4107USC	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
UM93_01690	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
UM93_01705	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
UM93_01715	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
UM93_01720	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
UM93_01725	ENOG4105CN5	Metallo-Beta-Lactamase
UM93_01730	ENOG4105CIR	epoxide hydrolase
UM93_01745	ENOG4105EQ7	Binding-protein-dependent transport systems, inner membrane component
UM93_01760	ENOG4105ETE	Transcriptional regulator (LacI family
UM93_01775	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
UM93_01780	ENOG4105DRS	transport system, permease
UM93_01795	ENOG4107QZI	cell division protein FtsK
UM93_01805	ENOG4105CEV	competence damage-inducible protein
UM93_01825	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
UM93_01830	ENOG4105KC9	Modulates RecA activity (By similarity)
UM93_01840	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
UM93_01845	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
UM93_01850	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
UM93_01855	ENOG4105C85	amino acid
UM93_01860	ENOG4107Y49	methyltransferase
UM93_01875	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
UM93_01885	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
UM93_01895	ENOG4105CIH	Imidazole acetol-phosphate transaminase
UM93_01900	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
UM93_01910	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
UM93_01940	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
UM93_01945	ENOG41084BS	50S ribosomal protein L35
UM93_01950	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
UM93_01955	ENOG4108RWN	rrna methyltransferase
UM93_01970	ENOG4105F27	Major Facilitator
UM93_01975	ENOG4105M6F	mutator MutT protein
UM93_01995	ENOG4105CEY	Amp-dependent synthetase and ligase
UM93_02010	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
UM93_02015	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
UM93_02020	ENOG4105CSR	polyphosphate kinase 2
UM93_02040	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
UM93_02050	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
UM93_02055	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
UM93_02060	ENOG4105CAS	nag kinase
UM93_02065	ENOG4105C8Y	Acetylornithine aminotransferase
UM93_02070	ENOG4105DBV	ornithine carbamoyltransferase
UM93_02075	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
UM93_02080	ENOG4105CDH	Citrulline--aspartate ligase
UM93_02085	ENOG4105CH7	arginosuccinase
UM93_02135	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
UM93_02160	ENOG4108VX5	3-methyladenine DNA glycosylase
UM93_02180	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
UM93_02190	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
UM93_02220	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
UM93_02225	ENOG4105BZU	Histidine kinase
UM93_02235	ENOG4105EDW	glycosyl transferase, family 39
UM93_02255	ENOG4105DSU	hydrolase
UM93_02275	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
UM93_02285	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
UM93_02310	ENOG4105WH1	Two component transcriptional regulator luxr family
UM93_02330	ENOG4105EMN	RNA polymerase sigma factor
UM93_02345	ENOG4105CR4	methylisocitrate lyase
UM93_02365	ENOG41086VY	Fic/DOC family
UM93_02370	ENOG4105CIK	Amidinotransferase
UM93_02375	ENOG4105E0A	ABC, transporter
UM93_02380	ENOG4105J76	Periplasmic binding protein
UM93_02385	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
UM93_02400	ENOG4105E93	esterase
UM93_02415	ENOG4108MRH	transcriptional regulatory protein
UM93_02425	ENOG4107QJT	sodium dicarboxylate symporter
UM93_02450	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
UM93_02465	ENOG4105CAT	Cytidine monophosphate kinase
UM93_02475	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
UM93_02500	ENOG4105EMU	Dehydrogenase
UM93_02525	ENOG4105DRS	transport system, permease
UM93_02540	ENOG4105ETE	Transcriptional regulator (LacI family
UM93_02545	ENOG4105DEF	Extracellular solute-binding protein, family 5
UM93_02570	ENOG4105CHP	RNA polymerase
UM93_02575	ENOG4105GRZ	Ycii-related protein
UM93_02600	ENOG4105HRU	Glyoxalase Bleomycin resistance protein (Dioxygenase
UM93_02605	ENOG4108Z4X	TRANSCRIPTIONal
UM93_02655	ENOG4108ZT1	Transcriptional regulator
UM93_02680	ENOG4107RCM	Releases the N-terminal proline from various substrates (By similarity)
UM93_02690	ENOG4105ETE	Transcriptional regulator (LacI family
UM93_02745	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
UM93_02760	ENOG4105DKQ	ROK family
UM93_02780	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
UM93_02790	ENOG4105K4H	Nlp p60 protein
UM93_02800	ENOG4105EAH	synthase
UM93_02810	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
UM93_02820	ENOG4108V6E	Cell division protein mraZ
UM93_02825	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
UM93_02835	ENOG4105CJN	penicillin-binding protein
UM93_02840	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
UM93_02845	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
UM93_02850	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
UM93_02855	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
UM93_02865	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
UM93_02880	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
UM93_02885	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
UM93_02895	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
UM93_02905	ENOG4107VQS	DivIVA family
UM93_02910	ENOG4107ZIW	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
UM93_02925	ENOG4105C0B	DNA polymerase III (alpha subunit)
UM93_02935	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
UM93_02940	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
UM93_02945	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
UM93_02960	ENOG4108NJC	
UM93_02965	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
UM93_02970	ENOG4105C5F	glutamine synthetase
UM93_02975	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
UM93_03000	ENOG4108UMI	ABC transporter, permease
UM93_03005	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
UM93_03010	ENOG4105D01	(LipO)protein
UM93_03035	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
UM93_03040	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
UM93_03050	ENOG4105ECP	epimerase
UM93_03055	ENOG4107RE3	peptidase, S41
UM93_03060	ENOG4108Z9K	Osmotically inducible protein
UM93_03090	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
UM93_03105	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
UM93_03115	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
UM93_03135	ENOG4105C4M	(Ubiquinol oxidase) subunit I
UM93_03140	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
UM93_03160	ENOG410814C	multidrug resistance protein
UM93_03165	ENOG4107RBI	VanW family
UM93_03175	ENOG410870F	Cyclic nucleotide-binding protein
UM93_03235	ENOG4107VEG	TrkA-N domain protein
UM93_03240	ENOG4105C0X	amino acid
UM93_03245	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
UM93_03320	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
UM93_03325	ENOG4107QM5	aconitate hydratase
UM93_03335	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
UM93_03350	ENOG4105CPC	Aldo Keto reductase
UM93_03355	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
UM93_03360	ENOG4108MRH	transcriptional regulatory protein
UM93_03365	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
UM93_03370	ENOG4105CHU	acetyl-coa acetyltransferase
UM93_03375	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
UM93_03400	ENOG4105E0X	reductase
UM93_03415	ENOG4108Z66	YbaK ebsC protein
UM93_03435	ENOG4105DKK	Benzoate
UM93_03445	ENOG4105KPY	Small multidrug resistance protein
UM93_03480	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
UM93_03485	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
UM93_03495	ENOG4105DJV	ribulose-phosphate 3-epimerase
UM93_03515	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
UM93_03520	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
UM93_03525	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
UM93_03530	ENOG4105M0N	phosphoribosyl-ATP pyrophosphatase
UM93_03535	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
UM93_03540	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
UM93_03550	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
UM93_03570	ENOG4105DK0	Indole-3-glycerol phosphate synthase
UM93_03580	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
UM93_03590	ENOG4105CBC	glutamate synthase
UM93_03635	ENOG4105BZF	Glycosyl transferase (Group 1
UM93_03640	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
UM93_03655	ENOG4105NAE	bifunctional deaminase-reductase domain protein
UM93_03665	ENOG4105KA0	thioesterase Superfamily protein
UM93_03700	ENOG4105HHS	UPF0256 protein
UM93_03705	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
UM93_03715	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
UM93_03730	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
UM93_03770	ENOG4105NPE	arsR family transcriptional regulator
UM93_03780	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
UM93_03800	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
UM93_03805	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
UM93_03815	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
UM93_03820	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
UM93_03825	ENOG4105CHW	UPF0052 protein
UM93_03830	ENOG4105CIE	May be required for sporulation (By similarity)
UM93_03835	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
UM93_03840	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
UM93_03845	ENOG4105BZA	Phosphoglycerate kinase
UM93_03865	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
UM93_03885	ENOG4107XKZ	Amino acid ABC superfamily ATP binding cassette transporter binding protein
UM93_03890	ENOG4105EAB	amino acid AbC transporter
UM93_03905	ENOG4105CP7	Triose-phosphate isomerase
UM93_03920	ENOG4107XU2	6-phosphogluconolactonase (EC 3.1.1.31)
UM93_03935	ENOG4105C89	phosphohexose isomerase
UM93_03940	ENOG4107QQX	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
UM93_03950	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
UM93_03965	ENOG4105CJ1	ABC, transporter
UM93_03970	ENOG4105CJN	penicillin-binding protein
UM93_03985	ENOG4105JRK	feS assembly protein SufD
UM93_03995	ENOG4105C3K	feS assembly ATPase SufC
UM93_04000	ENOG4105VG1	fes assembly suf system protein
UM93_04010	ENOG4105CMR	udp-glucose 4-epimerase
UM93_04015	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
UM93_04025	ENOG4105VKD	bioY protein
UM93_04030	ENOG4105C5H	ABC transporter
UM93_04055	ENOG4105CHR	reductase
UM93_04060	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
UM93_04070	ENOG4105DKW	ABC transporter
UM93_04090	ENOG4105NRA	50s ribosomal protein l31 type b
UM93_04120	ENOG4107ZR7	Membrane
UM93_04220	ENOG4107QPH	glycogen) synthase
UM93_04230	ENOG4105KBX	Transcriptional regulator, TetR family
UM93_04235	ENOG4105CHU	acetyl-coa acetyltransferase
UM93_04240	ENOG4105CHR	reductase
UM93_04270	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
UM93_04290	ENOG4105CPC	Aldo Keto reductase
UM93_04295	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
UM93_04300	ENOG4105C8N	cysteinyl-tRNA synthetase
UM93_04310	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
UM93_04325	ENOG4105DHM	ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis (By similarity)
UM93_04330	ENOG4105E5F	proteasome
UM93_04340	ENOG4105WFD	Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation (By similarity)
UM93_04345	ENOG4105KPK	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (By similarity)
UM93_04350	ENOG4105F7N	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (By similarity)
UM93_04355	ENOG4105DVV	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine (By similarity)
UM93_04375	ENOG4105C85	amino acid
UM93_04390	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
UM93_04395	ENOG4105CQR	helicase
UM93_04400	ENOG4105EFZ	amidohydrolase
UM93_04405	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
UM93_04410	ENOG4108SEA	Esterase
UM93_04430	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
UM93_04440	ENOG4105DHI	Methyltransferase
UM93_04445	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
UM93_04450	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
UM93_04460	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
UM93_04465	ENOG4105C6Z	Gluconate
UM93_04475	ENOG4105C22	threonyL-tRNA synthetase
UM93_04485	ENOG4108VTU	Cdp-alcohol phosphatidyltransferase
UM93_04490	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
UM93_04500	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
UM93_04505	ENOG4105DGW	oligopeptidase A
UM93_04510	ENOG4106178	UPF0339 protein
UM93_04515	ENOG4105CAQ	asparagine synthetase
UM93_04520	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
UM93_04525	ENOG4105CDY	transcriptional regulatory protein
UM93_04530	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
UM93_04535	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
UM93_04540	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
UM93_04555	ENOG4107RTU	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
UM93_04560	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
UM93_04570	ENOG4105C99	atpase involved in dna repair
UM93_04580	ENOG4105CUT	histidyl-tRNA synthetase
UM93_04590	ENOG4105C9M	aspartyl-trna synthetase
UM93_04600	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
UM93_04625	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
UM93_04640	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
UM93_04655	ENOG4105E2X	shikimate dehydrogenase
UM93_04660	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
UM93_04665	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
UM93_04670	ENOG4105D49	3-dehydroquinate synthase
UM93_04680	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
UM93_04685	ENOG410803B	Involved in the transcription termination process (By similarity)
UM93_04695	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
UM93_04700	ENOG4105CXT	aspartate transcarbamylase
UM93_04705	ENOG4105CD3	dihydroorotase
UM93_04715	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
UM93_04720	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
UM93_04725	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
UM93_04740	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
UM93_04745	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
UM93_04750	ENOG4105MTQ	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
UM93_04760	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
UM93_04775	ENOG4108EV1	Haloalkane dehalogenase
UM93_04780	ENOG4105CV8	reductase
UM93_04785	ENOG4107RHR	regulatoR
UM93_04795	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
UM93_04800	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
UM93_04810	ENOG4105C26	Dehydrogenase
UM93_04815	ENOG4105C8T	Leucyl-tRNA synthetase
UM93_04820	ENOG4105EPR	degv family
UM93_04840	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
UM93_04850	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
UM93_04870	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
UM93_04875	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
UM93_04885	ENOG4105CHR	reductase
UM93_04890	ENOG4107RSM	transcriptional regulator
UM93_04905	ENOG4107VNR	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
UM93_04915	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
UM93_04925	ENOG4105C9K	Endothelin-converting enzyme 1
UM93_04930	ENOG4107QXN	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
UM93_04940	ENOG4106DBE	Involved in DNA repair and RecF pathway recombination (By similarity)
UM93_04945	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
UM93_04950	ENOG4108EUD	Lysophospholipase
UM93_04965	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
UM93_04975	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
UM93_04985	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
UM93_04990	ENOG4105BZ9	Cytochrome C oxidase, subunit I
UM93_04995	ENOG4105MCD	Part of cytochrome c oxidase, its function is
UM93_05020	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
UM93_05025	ENOG4107EUI	c reductase, iron-sulfur
UM93_05030	ENOG4107UDY	cytochrome C
UM93_05035	ENOG4105CCU	oxidase (Subunit III)
UM93_05040	ENOG4108I0Q	anthranilate phosphoribosyltransferase
UM93_05095	ENOG4105C7K	acetolactate synthase
UM93_05110	ENOG4106NZI	LysR family Transcriptional regulator
UM93_05140	ENOG4105DRS	transport system, permease
UM93_05155	ENOG4108IG5	Transcriptional regulator
UM93_05185	ENOG4105NPE	arsR family transcriptional regulator
UM93_05190	ENOG41090KQ	Glyoxalase Bleomycin resistance protein (Dioxygenase
UM93_05200	ENOG4105F6J	Alpha beta hydrolase fold
UM93_05205	ENOG4105NAF	rna polymerase sigma factor
UM93_05235	ENOG4105ETS	cytosine purines uracil thiamine allantoin
UM93_05340	ENOG4108DMH	HTH_ARAC
UM93_05360	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
UM93_05365	ENOG4105CHP	RNA polymerase
UM93_05370	ENOG4105GRZ	Ycii-related protein
UM93_05405	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
UM93_05435	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
UM93_05445	ENOG4105G3E	Probably involved in ribonucleotide reductase function (By similarity)
UM93_05455	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
UM93_05460	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
UM93_05480	ENOG4105C26	Dehydrogenase
UM93_05485	ENOG4107QYE	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
UM93_05525	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
UM93_05530	ENOG4105CEY	Amp-dependent synthetase and ligase
UM93_05545	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
UM93_05575	ENOG4105ESI	atpase involved in dna repair
UM93_05615	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
UM93_05625	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
UM93_05635	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
UM93_05640	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
UM93_05645	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
UM93_05650	ENOG4105K46	50S ribosomal protein l27
UM93_05655	ENOG410826X	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
UM93_05665	ENOG4105C03	ribonuclease
UM93_05675	ENOG4105C31	Tryptophanyl-tRNA synthetase
UM93_05695	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
UM93_05705	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
UM93_05730	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
UM93_05735	ENOG4105MC2	DSBA oxidoreductase
UM93_05745	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
UM93_05750	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
UM93_05755	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
UM93_05765	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
UM93_05795	ENOG4108YZG	isomerase
UM93_05805	ENOG4108Q27	Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate (By similarity)
UM93_05835	ENOG4108IAJ	Nad-dependent epimerase dehydratase
UM93_05865	ENOG4105C29	acyl-CoA thioesterase
UM93_05955	ENOG41090CE	integral membrane protein
UM93_05960	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
UM93_06005	ENOG4105NDH	peptidase s1 and s6 chymotrypsin hap
UM93_06050	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
UM93_06055	ENOG4107XFJ	UPF0246 protein
UM93_06065	ENOG4105EGD	dinuclear metal center protein, YbgI family
UM93_06070	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
UM93_06080	ENOG4105D7W	serine acetyltransferase
UM93_06085	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
UM93_06095	ENOG4105DUM	transcriptional regulator, lysR family
UM93_06100	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
UM93_06115	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
UM93_06125	ENOG4105D9U	N-acetyltransferase
UM93_06150	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
UM93_06160	ENOG4105EQ6	Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids (By similarity)
UM93_06175	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
UM93_06180	ENOG41082KT	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
UM93_06195	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
UM93_06200	ENOG4105C79	DNA protecting protein DprA
UM93_06205	ENOG4105C0P	Mg chelatase subunit ChlI
UM93_06210	ENOG41080R2	UPF0102 protein
UM93_06220	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
UM93_06230	ENOG4107QYR	Signal peptidase i
UM93_06235	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
UM93_06240	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
UM93_06245	ENOG4107XUM	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
UM93_06250	ENOG41082KU	UPF0109 protein
UM93_06255	ENOG4105K5M	30s ribosomal protein S16
UM93_06265	ENOG4108TKW	Glyoxalase Bleomycin resistance protein (Dioxygenase
UM93_06275	ENOG4105XYF	acetyltransferase
UM93_06280	ENOG4105CMG	Carbohydrate kinase
UM93_06290	ENOG41068WN	
UM93_06295	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
UM93_06315	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
UM93_06335	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
UM93_06340	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
UM93_06345	ENOG41062IY	50S ribosomal protein L32
UM93_06355	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
UM93_06370	ENOG4106H78	methyltransferase
UM93_06380	ENOG4105DP4	dak2 domain fusion protein ylov
UM93_06395	ENOG4105CPF	Cell wall formation (By similarity)
UM93_06400	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
UM93_06410	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
UM93_06415	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
UM93_06420	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
UM93_06425	ENOG41069M3	Transcriptional regulator
UM93_06460	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
UM93_06465	ENOG4105ERH	Fumarylacetoacetate hydrolase
UM93_06470	ENOG4105CM2	brancheD-chain amino acid aminotransferase
UM93_06475	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
UM93_06480	ENOG4105BZU	Histidine kinase
UM93_06485	ENOG4105WH1	Two component transcriptional regulator luxr family
UM93_06490	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
UM93_06495	ENOG4105D60	lipoprotein releasing system transmembrane protein
UM93_06505	ENOG4108ZHR	arsR family transcriptional regulator
UM93_06520	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
UM93_06525	ENOG4108ZP8	Acetolactate synthase small subunit
UM93_06535	ENOG4105C01	Dihydroxy-acid dehydratase
UM93_06560	ENOG4106KE4	Dehydrogenase
UM93_06580	ENOG4105CPC	Aldo Keto reductase
UM93_06585	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
UM93_06600	ENOG4105PF9	Transcriptional regulator
UM93_06630	ENOG4105DEF	Extracellular solute-binding protein, family 5
UM93_06635	ENOG4105DWT	malate dehydrogenase (quinone)
UM93_06655	ENOG41079Y2	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone
UM93_06675	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
UM93_06695	ENOG4107R1M	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) (By similarity)
UM93_06700	ENOG4107QI6	Cysteine desulfurase
UM93_06705	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
UM93_06715	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
UM93_06730	ENOG4105C85	amino acid
UM93_06740	ENOG4105CPP	Dehydrogenase, E1 component
UM93_06745	ENOG4107RN0	branched-chain alpha-keto acid dehydrogenase subunit E2
UM93_06750	ENOG4108MXF	Alpha Beta Hydrolase
UM93_06765	ENOG4107TPY	serine threonine protein kinase
UM93_06770	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
UM93_06780	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
UM93_06785	ENOG4105C26	Dehydrogenase
UM93_06805	ENOG4105CHR	reductase
UM93_06835	ENOG4105C0Z	ABC transporter
UM93_06840	ENOG4108IV0	ABC, transporter
UM93_06860	ENOG4105RHY	Pfam:UPF0157
UM93_06885	ENOG4105C26	Dehydrogenase
UM93_06900	ENOG4105CK5	oxidoreductase
UM93_06915	ENOG41069M3	Transcriptional regulator
UM93_06925	ENOG4105EYH	Exonuclease
UM93_06930	ENOG4107RH8	nuclease SbcCD subunit D
UM93_06965	ENOG4105EJU	HAD-superfamily hydrolase subfamily IA variant 3
UM93_06975	ENOG4105DVE	abc transporter atp-binding protein
UM93_06995	ENOG4105EEQ	Na H antiporter
UM93_07005	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
UM93_07010	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
UM93_07020	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
UM93_07040	ENOG4108RWI	nicotinamidase
UM93_07060	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
UM93_07100	ENOG4105CYV	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures (By similarity)
UM93_07105	ENOG4105CE4	GlcNAc 6-P deacetylase
UM93_07115	ENOG4108Z4X	TRANSCRIPTIONal
UM93_07130	ENOG410825K	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
UM93_07135	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
UM93_07140	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
UM93_07145	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
UM93_07150	ENOG4108T62	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
UM93_07155	ENOG4107Z0K	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
UM93_07160	ENOG4106DE0	ATP synthase
UM93_07165	ENOG4107UH5	it plays a direct role in the translocation of protons across the membrane (By similarity)
UM93_07185	ENOG4108MKI	Glycosyl transferase, family 2
UM93_07195	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
UM93_07200	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
UM93_07210	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
UM93_07215	ENOG4107R5I	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
UM93_07220	ENOG4105D6E	homoserine dehydrogenase
UM93_07225	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
UM93_07230	ENOG4105C75	arginyL-tRNA synthetase
UM93_07240	ENOG4105DJ2	Major Facilitator Superfamily
UM93_07255	ENOG4108JA0	Oxidoreductase, FAD NAD(P)-binding domain protein
UM93_07280	ENOG4105CQ7	ATP-dependent helicase
UM93_07290	ENOG4105DQ4	alcohol dehydrogenase
UM93_07305	ENOG4105I4A	GCN5-related N-acetyltransferase
UM93_07320	ENOG4105CC5	ABC transporter
UM93_07325	ENOG4105DIK	(ABC) transporter
UM93_07340	ENOG4105C37	(CBS) domain
UM93_07350	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
UM93_07390	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
UM93_07395	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
UM93_07400	ENOG4107TK4	histidinol-phosphate phosphatase
UM93_07420	ENOG4107R5H	iron (metal) dependent repressor, dtxr family
UM93_07425	ENOG410814D	Protein CrcB homolog
UM93_07430	ENOG410814D	Protein CrcB homolog
UM93_07450	ENOG4108QB1	triacylglycerol lipase EC 3.1.1.3
UM93_07465	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
UM93_07475	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
UM93_07480	ENOG4105DR5	peptidase
UM93_07485	ENOG4107RYD	Part of the ABC transporter FtsEX involved in cellular division (By similarity)
UM93_07490	ENOG4105CAK	Cell division ATP-binding protein ftsE
UM93_07495	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
UM93_07585	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
UM93_07590	ENOG4108IAJ	Nad-dependent epimerase dehydratase
UM93_07595	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
UM93_07605	ENOG4105D2T	synthase
UM93_07615	ENOG4105F0R	Cytidylyltransferase
UM93_07640	ENOG4105CKK	Glycosyl transferase, family 2
UM93_07655	ENOG4105EXC	Acyl-transferase
UM93_07670	ENOG4105EY8	ABC transporter
UM93_07680	ENOG410602S	Transferase
UM93_07695	ENOG4105KRM	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
UM93_07705	ENOG4105C7I	Dehydrogenase
UM93_07745	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
UM93_07750	ENOG4105T0Z	Conserved Protein
UM93_07755	ENOG4108S7Q	sigma 54 modulation protein ribosomal protein S30ea
UM93_07765	ENOG4108T3R	lipoprotein lpqB
UM93_07775	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
UM93_07800	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
UM93_07815	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
UM93_07820	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
UM93_07855	ENOG4108JQ6	ABC transporter
UM93_07860	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
UM93_07865	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
UM93_07875	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
UM93_07885	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
UM93_07900	ENOG4105E5T	Major Facilitator Superfamily
UM93_07940	ENOG4105DWV	Homoserine O-trans-acetylase
UM93_07945	ENOG4108IQK	o-acetylhomoserine
UM93_07975	ENOG4105DBE	peroxidase
UM93_07985	ENOG4105E98	transcriptional regulator DeoR family
UM93_08005	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
UM93_08010	ENOG4105ESP	cell wall surface anchor family protein
UM93_08040	ENOG4105CI2	imidazolone-5-propionate hydrolase
UM93_08050	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
UM93_08055	ENOG4105CGP	Urocanate hydratase
UM93_08065	ENOG4105C84	Histidine ammonia-lyase
UM93_08070	ENOG410829K	Lysine exporter protein (Lyse ygga)
UM93_08095	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
UM93_08100	ENOG4105CPQ	Dehydrogenase
UM93_08130	ENOG4105ETE	Transcriptional regulator (LacI family
UM93_08140	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
UM93_08155	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
UM93_08160	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
UM93_08165	ENOG41081AP	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
UM93_08180	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
UM93_08185	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
UM93_08195	ENOG41082K6	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
UM93_08200	ENOG4105K6V	RNA polymerase
UM93_08210	ENOG4107TXC	Transcriptional regulator
UM93_08215	ENOG4105C10	Electron transfer flavoprotein
UM93_08220	ENOG4105BZJ	Electron transfer flavoprotein
UM93_08235	ENOG4105C0H	protease
UM93_08250	ENOG41087YS	Phage shock protein A
UM93_08265	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
UM93_08275	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
UM93_08315	ENOG41063PX	domain protein
UM93_08365	ENOG4105EAB	amino acid AbC transporter
UM93_08370	ENOG4105DRP	amino acid AbC transporter
UM93_08380	ENOG4105CIR	epoxide hydrolase
UM93_08395	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
UM93_08405	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
UM93_08415	ENOG4105D52	delta-aminolevulinic acid dehydratase
UM93_08425	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
UM93_08430	ENOG4107QME	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
UM93_08435	ENOG4107JTW	chlorite dismutase
UM93_08440	ENOG4105C1Q	protoporphyrinogen oxidase
UM93_08460	ENOG4108R86	Transcriptional regulator
UM93_08475	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
UM93_08500	ENOG4108IEC	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction (By similarity)
UM93_08510	ENOG4105C1J	atp-dependent rna helicase
UM93_08525	ENOG4105EHG	Permease protein
UM93_08530	ENOG4107R4I	Periplasmic binding protein
UM93_08545	ENOG4105DB7	PHP domain protein
UM93_08550	ENOG4107T6F	Xaa-Pro aminopeptidase
UM93_08570	ENOG4105CJW	magnesium transporter
UM93_08585	ENOG410887T	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
UM93_08595	ENOG4105DU6	RNA polymerase
UM93_08615	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
UM93_08630	ENOG4105CDA	abc transporter atp-binding protein
UM93_08635	ENOG4107UBR	Extracellular solute-binding protein family 3
UM93_08640	ENOG4108Q1T	ABC transporter
UM93_08645	ENOG4105DRP	amino acid AbC transporter
UM93_08660	ENOG4107R4C	succinyl-diaminopimelate desuccinylase
UM93_08665	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
UM93_08690	ENOG4108Z4U	Ferredoxin
UM93_08700	ENOG4105DWF	phosphomethylpyrimidine kinase
UM93_08705	ENOG4108KZ5	Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway (By similarity)
UM93_08710	ENOG4105CI3	gtp-binding protein typa
UM93_08725	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
UM93_08730	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
UM93_08755	ENOG41068WN	
UM93_08765	ENOG4105C3G	gtp-binding protein
UM93_08770	ENOG4105CGY	Dna recombination protein
UM93_08775	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
UM93_08785	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
UM93_08790	ENOG4105YX8	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
UM93_08795	ENOG4105CSR	polyphosphate kinase 2
UM93_08815	ENOG4105E90	ABC transporter
UM93_08820	ENOG4108IJ8	ABC transporter
UM93_08840	ENOG4105CUB	amino acid
UM93_08850	ENOG4108JW7	Maf-like protein
UM93_08855	ENOG4105EUB	pirin domain protein
UM93_08860	ENOG4105RD7	BadF BadG BcrA BcrD
UM93_08870	ENOG4105FKN	transcriptional regulator, AsnC family
UM93_08885	ENOG4105D7N	magnesium and cobalt transport protein CorA
UM93_08895	ENOG4105CV8	reductase
UM93_08900	ENOG4107SET	aldo keto reductase
UM93_08910	ENOG4105PDP	Short chain dehydrogenase
UM93_08955	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
UM93_08980	ENOG4105VG5	Membrane
UM93_09015	ENOG4105SKE	transcriptional Regulator LysR family
UM93_09100	ENOG4106KE4	Dehydrogenase
UM93_09105	ENOG4105KVH	Transcriptional regulator
UM93_09130	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
UM93_09155	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
UM93_09170	ENOG4105BZ1	(ABC) transporter
UM93_09175	ENOG4105BZ1	(ABC) transporter
UM93_09215	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
UM93_09225	ENOG4105EXC	Acyl-transferase
UM93_09230	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
UM93_09235	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
UM93_09245	ENOG4105F9E	Shikimate 5-dehydrogenase
UM93_09250	ENOG4108638	50S ribosomal protein L36
UM93_09260	ENOG4106KXD	ATP-dependent carboxylate-amine ligase (By similarity)
UM93_09265	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
UM93_09290	ENOG4108097	ATP-binding protein
UM93_09295	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
UM93_09305	ENOG4105F8D	glycoside hydrolase family 4
UM93_09320	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
UM93_09325	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
UM93_09330	ENOG4105CKU	formyltetrahydrofolate synthetase
UM93_09335	ENOG4105CZA	synthase
UM93_09340	ENOG4105CPC	Aldo Keto reductase
UM93_09345	ENOG4105ETE	Transcriptional regulator (LacI family
UM93_09370	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
UM93_09375	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
UM93_09380	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
UM93_09405	ENOG4107QTJ	carbohydrate kinase, YjeF related protein
UM93_09410	ENOG41082KK	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
UM93_09430	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
UM93_09435	ENOG4105CS9	pantothenic acid kinase
UM93_09445	ENOG41080FJ	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
UM93_09450	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
UM93_09455	ENOG4108UJD	30S ribosomal protein S9
UM93_09460	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
UM93_09465	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
UM93_09470	ENOG4108ZT0	50S ribosomal protein l17
UM93_09475	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
UM93_09480	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
UM93_09485	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
UM93_09495	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
UM93_09500	ENOG4105KXX	peptidase s58 dmpa
UM93_09505	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
UM93_09525	ENOG4105C1G	acyl-Coa dehydrogenase
UM93_09540	ENOG410900P	UPF0336 protein
UM93_09550	ENOG410630P	Transcriptional regulator
UM93_09555	ENOG4105CEY	Amp-dependent synthetase and ligase
UM93_09560	ENOG4105EBR	Carboxylesterase
UM93_09580	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
UM93_09590	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
UM93_09595	ENOG410849U	50S ribosomal protein L30
UM93_09600	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
UM93_09605	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
UM93_09610	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
UM93_09615	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
UM93_09620	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
UM93_09625	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
UM93_09630	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
UM93_09650	ENOG4105EG6	Saccharopine dehydrogenase
UM93_09655	ENOG4105CEY	Amp-dependent synthetase and ligase
UM93_09665	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
UM93_09670	ENOG41082SA	50s ribosomal protein l29
UM93_09675	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
UM93_09680	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
UM93_09685	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
UM93_09690	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
UM93_09695	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
UM93_09700	ENOG4105KZR	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
UM93_09705	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
UM93_09710	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
UM93_09715	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
UM93_09725	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
UM93_09745	ENOG4105D2S	major facilitator superfamily
UM93_09750	ENOG4107RSM	transcriptional regulator
UM93_09755	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
UM93_09760	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
UM93_09765	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
UM93_09770	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
UM93_09775	ENOG4108K8S	endonuclease I
UM93_09795	ENOG4105CY5	solute-binding protein
UM93_09810	ENOG4107STF	Involved in phosphonate degradation (By similarity)
UM93_09820	ENOG4105C57	major facilitator superfamily
UM93_09835	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
UM93_09840	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
UM93_09865	ENOG4105CHU	acetyl-coa acetyltransferase
UM93_09870	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
UM93_09885	ENOG4105ETE	Transcriptional regulator (LacI family
UM93_09895	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
UM93_09910	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
UM93_09915	ENOG4108VZM	50s ribosomal protein L10
UM93_09950	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
UM93_09955	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
UM93_09965	ENOG410683Z	Preprotein translocase SecE subunit
UM93_09980	ENOG4105WH1	Two component transcriptional regulator luxr family
UM93_10015	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
UM93_10020	ENOG4108X6U	May play a role in the intracellular transport of hydrophobic ligands
UM93_10030	ENOG4107NHD	transcriptional regulator
UM93_10035	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
UM93_10040	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
UM93_10060	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
UM93_10070	ENOG4107QJH	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
UM93_10100	ENOG4108JU3	Alkyl hydroperoxide reductase
UM93_10125	ENOG4105CJ1	ABC, transporter
UM93_10135	ENOG4107R4N	Cell wall formation (By similarity)
UM93_10140	ENOG4106UW1	Major Facilitator superfamily
UM93_10150	ENOG410900P	UPF0336 protein
UM93_10160	ENOG4107WHG	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
UM93_10175	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
UM93_10180	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
UM93_10190	ENOG4107V2S	Transcriptional regulator
UM93_10210	ENOG4105C57	major facilitator superfamily
UM93_10225	ENOG4107TMB	Transcriptional regulator
UM93_10235	ENOG4105CI0	Citrate lyase
UM93_10285	ENOG4105KVH	Transcriptional regulator
UM93_10350	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
UM93_10370	ENOG4105DVH	amino acid
UM93_10380	ENOG4105CI2	imidazolone-5-propionate hydrolase
UM93_10385	ENOG4105C1G	acyl-Coa dehydrogenase
UM93_10395	ENOG4105VZ8	Transcriptional regulator
UM93_10410	ENOG4105NDH	peptidase s1 and s6 chymotrypsin hap
UM93_10420	ENOG4107YPT	transcriptional regulator
UM93_10435	ENOG4107R84	Peptidase dimerisation domain
UM93_10445	ENOG4105E0Y	RtcB Protein
UM93_10465	ENOG41080RH	Thioredoxin
UM93_10485	ENOG4108X07	Tetr family transcriptional regulator
UM93_10490	ENOG4105CIG	ABC transporter
UM93_10500	ENOG4105DXB	Major Facilitator superfamily
UM93_10510	ENOG41080V3	Major Facilitator superfamily
UM93_10540	ENOG4108VPT	UPF0234 protein
UM93_10555	ENOG4105WH1	Two component transcriptional regulator luxr family
UM93_10570	ENOG4105E8G	Major facilitator Superfamily
UM93_10590	ENOG4105CH6	catalase
UM93_10615	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
UM93_10630	ENOG4105C26	Dehydrogenase
UM93_10645	ENOG4105US7	Histidine kinase
UM93_10650	ENOG4105ETX	regulatoR
UM93_10655	ENOG410841Q	phosphoesterase PA-phosphatase related protein
UM93_10665	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
UM93_10680	ENOG4108IY8	ABC, transporter
UM93_10720	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
UM93_10725	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
UM93_10740	ENOG4105EN6	Membrane
UM93_10765	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
UM93_10770	ENOG4105E4F	Isochorismate synthase
UM93_10795	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
UM93_10800	ENOG4107TCW	O-succinylbenzoate synthase
UM93_10840	ENOG4107RN0	branched-chain alpha-keto acid dehydrogenase subunit E2
UM93_10845	ENOG4105CPP	Dehydrogenase, E1 component
UM93_10855	ENOG4105EW9	transcriptional regulator AsnC family
UM93_10870	ENOG4105CGU	Enoyl-CoA hydratase
UM93_10875	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
UM93_10880	ENOG4108ZA2	phenylacetate-CoA oxygenase PaaJ subunit
UM93_10885	ENOG4105D9S	phenylacetate-CoA oxygenase PaaI subunit
UM93_10890	ENOG4105N76	Phenylacetate-CoA oxygenase, subunit
UM93_10895	ENOG4105CRS	phenylacetate-CoA oxygenase PaaG subunit
UM93_10910	ENOG4108TCS	Glutamyl endopeptidase
UM93_10920	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
UM93_10925	ENOG4105C6K	Malic enzyme
UM93_10960	ENOG4105CPQ	Dehydrogenase
UM93_10970	ENOG41079KZ	Major Facilitator Superfamily
UM93_10985	ENOG4105DXM	phenylacetic acid degradation protein
UM93_10990	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
UM93_10995	ENOG4105KA0	thioesterase Superfamily protein
UM93_11020	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
UM93_11025	ENOG4105E39	Enoyl-CoA hydratase
UM93_11030	ENOG4105CHU	acetyl-coa acetyltransferase
UM93_11050	ENOG4107SIQ	Naphthoate synthase
UM93_11095	ENOG4105CRE	cytochrome C
UM93_11105	ENOG4107QIV	Cytochrome c biogenesis protein
UM93_11115	ENOG4108RH7	phosphoglycerate mutase
UM93_11120	ENOG4108YYC	ycei family
UM93_11135	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
UM93_11145	ENOG4108RXW	HAD-superfamily subfamily IB hydrolase
UM93_11155	ENOG41073TP	transcriptional regulator
UM93_11165	ENOG41082SX	arsR family transcriptional regulator
UM93_11170	ENOG4105DGU	Histone deacetylase
UM93_11185	ENOG4105II7	pyrroline-5-carboxylate reductase
UM93_11190	ENOG4105EY0	Xylose isomerase domain protein TIM barrel
UM93_11195	ENOG4107R33	ppx gppa phosphatase
UM93_11200	ENOG4105CTZ	aminopeptidase c
UM93_11205	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
UM93_11210	ENOG4105WH1	Two component transcriptional regulator luxr family
UM93_11220	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
UM93_11225	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
UM93_11235	ENOG4108I5C	dEAD DEAH box helicase
UM93_11285	ENOG4105EBM	Alpha Beta Hydrolase Fold protein
UM93_11310	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
UM93_11325	ENOG4105I1K	ABC transporter
UM93_11330	ENOG4105E98	transcriptional regulator DeoR family
UM93_11345	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
UM93_11370	ENOG4105BZ4	penicillin-binding protein
UM93_11375	ENOG4107RGJ	metallophosphoesterase
UM93_11380	ENOG4108M8W	Monooxygenase
UM93_11390	ENOG4105BZ1	(ABC) transporter
UM93_11395	ENOG4105BZ1	(ABC) transporter
UM93_11405	ENOG4105CDA	abc transporter atp-binding protein
UM93_11410	ENOG4105E5Q	amino acid AbC transporter
UM93_11415	ENOG4105DRP	amino acid AbC transporter
UM93_11430	ENOG4105DRR	Transcriptional regulator, GntR family
UM93_11435	ENOG4105C1G	acyl-Coa dehydrogenase
UM93_11440	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
UM93_11465	ENOG4105C26	Dehydrogenase
UM93_11485	ENOG4105C8V	SAICAR synthetase
UM93_11520	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
UM93_11540	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
UM93_11560	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
UM93_11575	ENOG4108FN7	Aldo keto reductase
UM93_11580	ENOG4105CUB	amino acid
UM93_11590	ENOG41090B9	response to stress
UM93_11595	ENOG4105C1J	atp-dependent rna helicase
UM93_11605	ENOG4105D94	Major Facilitator Superfamily
UM93_11610	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
UM93_11620	ENOG4105KNI	merR family transcriptional Regulator
UM93_11625	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
UM93_11630	ENOG4108093	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
UM93_11635	ENOG4105CFG	Acts as a chaperone (By similarity)
UM93_11670	ENOG4105CPQ	Dehydrogenase
UM93_11675	ENOG4105CHR	reductase
UM93_11705	ENOG4105ETE	Transcriptional regulator (LacI family
UM93_11725	ENOG4108J59	Extracellular solute-binding protein, family 5
UM93_11740	ENOG4108JQ6	ABC transporter
UM93_11745	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
UM93_11750	ENOG4105CS2	ec 3.2.1.21
UM93_11760	ENOG4105KJF	protein tyrosine phosphatase
UM93_11785	ENOG4105BZ1	(ABC) transporter
UM93_11830	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
UM93_11840	ENOG4108JJB	ABC transporter
UM93_11845	ENOG4105NSK	ABC superfamily ATP binding cassette transporter membrane protein
UM93_11865	ENOG4105KJM	monovalent cation h antiporter subunit g
UM93_11880	ENOG4108JPZ	Monovalent cation H antiporter subunit D
UM93_11885	ENOG4105MKQ	Monovalent cation H antiporter subunit C
UM93_11905	ENOG4105DHP	deoxycytidine triphosphate deaminase
UM93_11910	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
UM93_11950	ENOG4105EGI	Transcriptional regulator
UM93_11960	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
UM93_11970	ENOG4105D7A	ATP-binding protein
UM93_11980	ENOG4105E8R	UPF0173 metal-dependent hydrolase
UM93_11990	ENOG4107YEV	ferritin
UM93_12010	ENOG4108426	dNA-binding protein
UM93_12015	ENOG4105CPC	Aldo Keto reductase
UM93_12025	ENOG41080FR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
UM93_12030	ENOG4105W0E	50S ribosomal protein L33
UM93_12035	ENOG4105KDC	50s ribosomal protein l28
UM93_12040	ENOG4105D4T	Citrate transporter
UM93_12085	ENOG4108JA1	polyketide synthase
UM93_12100	ENOG4105TVJ	transport system, permease
UM93_12105	ENOG4105DQ5	transport system permease protein
UM93_12120	ENOG4105CHF	Glutathione S-transferase
UM93_12125	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
UM93_12135	ENOG4105ECR	NmrA family
UM93_12150	ENOG4105E09	nadh pyrophosphatase
UM93_12165	ENOG4105C87	Aminotransferase class I and II
UM93_12215	ENOG4105D9R	oxidoreductase
UM93_12225	ENOG4105DCF	alanine dehydrogenase
UM93_12260	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
UM93_12265	ENOG4107RN0	branched-chain alpha-keto acid dehydrogenase subunit E2
UM93_12270	ENOG4105CPP	Dehydrogenase, E1 component
UM93_12285	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
UM93_12290	ENOG4105CIH	Imidazole acetol-phosphate transaminase
UM93_12300	ENOG4107QTF	adenylosuccinate lyase
UM93_12345	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
UM93_12350	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
UM93_12390	ENOG4105K4P	CoA-binding domain protein
UM93_12400	ENOG4105FBW	Monooxygenase
UM93_12405	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
UM93_12420	ENOG4105JXH	GntR family transcriptional regulator
UM93_12435	ENOG4105M10	Involved in the anomeric conversion of L-rhamnose (By similarity)
UM93_12450	ENOG4105CNN	ABC, transporter
UM93_12460	ENOG4105DIA	mandelate racemase muconate lactonizing
UM93_12475	ENOG4105C9U	ATP-dependent DNA helicase RecQ
UM93_12480	ENOG4107QKV	phosphomannomutase
UM93_12490	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
UM93_12515	ENOG4107QN2	dihydrolipoyl dehydrogenase
UM93_12535	ENOG4105DBE	peroxidase
UM93_12550	ENOG4105ECB	domain protein
UM93_12555	ENOG4108IG5	Transcriptional regulator
UM93_12580	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
UM93_12585	ENOG4105BZU	Histidine kinase
UM93_12610	ENOG4108FKE	two-component system sensor kinase
UM93_12615	ENOG4108PYU	two-component system response regulator
UM93_12630	ENOG4105EXC	Acyl-transferase
UM93_12640	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
UM93_12645	ENOG4108Z6B	deaminase
UM93_12685	ENOG4108VUG	Enoyl-CoA hydratase
UM93_12695	ENOG4108N16	Negative regulator of allantoin and glyoxylate utilization operons. Binds to the gcl promoter and to the allS- allA intergenic region
UM93_12720	ENOG4107QRT	dEAD DEAH box helicase
UM93_12725	ENOG4108S0J	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized pyrimidines, such as thymine glycol, 5,6-dihydrouracil and 5,6-dihydrothymine. Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'- phosphates (By similarity)
UM93_12730	ENOG4105DR9	pseudouridine synthase
UM93_12820	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
UM93_12825	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
UM93_12840	ENOG4105D5Q	Arginine ornithine antiporter
UM93_12865	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
UM93_12870	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
UM93_12875	ENOG4105DWF	phosphomethylpyrimidine kinase
UM93_12880	ENOG4105NDH	peptidase s1 and s6 chymotrypsin hap
UM93_12890	ENOG4105KVH	Transcriptional regulator
UM93_12915	ENOG4105HZM	Fha domain containing protein
UM93_12935	ENOG4107TPY	serine threonine protein kinase
UM93_12955	ENOG4108U4N	(sortase) family
UM93_12960	ENOG4105ZJT	Cell division protein CrgA
UM93_12965	ENOG4105BZN	citrate synthase
UM93_12970	ENOG4105BZN	citrate synthase
UM93_13015	ENOG4105NAE	bifunctional deaminase-reductase domain protein
UM93_13065	ENOG4105Y3U	Transglycosylase-associated protein
UM93_13070	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
UM93_13095	ENOG4105QPS	Monooxygenase
UM93_13100	ENOG4105Q26	Siderophore-interacting protein
UM93_13105	ENOG4105PEC	Iron-enterobactin transporter periplasmic binding protein
UM93_13110	ENOG4105DQ5	transport system permease protein
UM93_13115	ENOG4105TVJ	transport system, permease
UM93_13120	ENOG4105E0A	ABC, transporter
UM93_13150	ENOG4105ENE	Histidine kinase
UM93_13155	ENOG4105WH1	Two component transcriptional regulator luxr family
UM93_13175	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
UM93_13210	ENOG4105BZ1	(ABC) transporter
UM93_13235	ENOG410814C	multidrug resistance protein
UM93_13335	ENOG4108KXV	response regulator
UM93_13340	ENOG4105VPX	protein, conserved in bacteria
UM93_13375	ENOG41060NJ	transcriptional regulator
UM93_13390	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
UM93_13430	ENOG4107SM8	Adenylate Guanylate cyclase
UM93_13460	ENOG4105CND	Glycosyl transferase, family 2
UM93_13480	ENOG4108ZED	Transmembrane domain of unknown function (DUF3566)
UM93_13485	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
UM93_13490	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
UM93_13500	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
UM93_13505	ENOG4108J5G	6-phosphogluconate dehydrogenase
UM93_13510	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
UM93_13515	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
UM93_13525	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
UM93_13530	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
UM93_13535	ENOG4108Z7S	Single-stranded nucleic acid binding R3H domain-containing protein
UM93_13540	ENOG4107XUG	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
UM93_13545	ENOG4107QJE	Chromosome Partitioning Protein
UM93_13555	ENOG4105K63	Thioredoxin
UM93_13560	ENOG4105C3M	thioredoxin reductase
UM93_13605	ENOG4108RYK	Nad-dependent epimerase dehydratase
UM93_13610	ENOG4105KVH	Transcriptional regulator
UM93_13620	ENOG4105ETE	Transcriptional regulator (LacI family
UM93_13640	ENOG4106UW1	Major Facilitator superfamily
UM93_13665	ENOG4105WH1	Two component transcriptional regulator luxr family
UM93_13680	ENOG4105DFM	M18 family aminopeptidase
UM93_13690	ENOG4105CSH	Transporter
UM93_13700	ENOG410829C	Binds together with S18 to 16S ribosomal RNA (By similarity)
UM93_13710	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
UM93_13715	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
UM93_13730	ENOG4105CDU	Replicative dna helicase
UM93_13755	ENOG4105CTU	Proline racemase
UM93_13760	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
UM93_13780	ENOG4108WYP	Transcriptional regulator
UM93_13820	ENOG4105YVS	arsR family transcriptional regulator
UM93_13825	ENOG4107QI1	Mate efflux family protein
UM93_13845	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
UM93_13850	ENOG4108SU4	UPF0309 protein
UM93_13860	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
UM93_13865	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
UM93_13930	ENOG4105DEI	Mannitol dehydrogenase
UM93_13935	ENOG4105C0B	DNA polymerase III (alpha subunit)
UM93_13965	ENOG4105DPV	During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co- crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2 ) ion and storing it in the form of Fe(3 ) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2 ) ions, which prevents hydroxyl radical production by the Fenton reaction
UM93_13970	ENOG4105C09	Bile acid
UM93_14040	ENOG4105BZW	Glycerate kinase
UM93_14085	ENOG4105C75	arginyL-tRNA synthetase
UM93_14100	ENOG4105DUX	Transporter
UM93_14105	ENOG4105EC3	peptidase S51, dipeptidase E
UM93_14110	ENOG4105VFE	sira family
UM93_14120	ENOG4108UW5	maltose o-acetyltransferase
UM93_14125	ENOG4107TE5	Lipid kinase
UM93_14130	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
UM93_14135	ENOG4108KP7	hydrolase
UM93_14160	ENOG4105F0N	pyrophosphate phospho-hydrolase
UM93_14165	ENOG4107RVU	D-Ala-D-Ala carboxypeptidase 3 (S13) family
UM93_14175	ENOG4107RD1	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
UM93_14185	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
UM93_14190	ENOG4105EUJ	GTP cyclohydrolase i
UM93_14205	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
UM93_14230	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
UM93_14235	ENOG4108US0	Transcription regulator that can specifically activate or repress expression of target genes (By similarity)
UM93_14240	ENOG4105F27	Major Facilitator
UM93_14245	ENOG4105CRK	lysyL-tRNA synthetase
UM93_14255	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
UM93_14260	ENOG4108SEA	Esterase
UM93_14270	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
UM93_14285	ENOG4105CMT	Dihydroxyacetone kinase
UM93_14290	ENOG4108UTZ	Dihydroxyacetone kinase
UM93_14295	ENOG4105VDH	Dihydroxyacetone kinase
UM93_14330	ENOG4105E59	Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions (By similarity)
UM93_14350	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
UM93_14365	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
UM93_14370	ENOG4105CJ3	phosphate transporter
UM93_14710	ENOG4105KVH	Transcriptional regulator
UM93_14750	ENOG4105F27	Major Facilitator
UM93_14760	ENOG4105NDH	peptidase s1 and s6 chymotrypsin hap
UM93_14815	ENOG4105EA8	2-Nitropropane dioxygenase
UM93_14820	ENOG4108EIM	Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities (By similarity)
UM93_14825	ENOG4105CHU	acetyl-coa acetyltransferase
UM93_14835	ENOG4105BZJ	Electron transfer flavoprotein
UM93_14840	ENOG4105C10	Electron transfer flavoprotein
UM93_14865	ENOG4105CEY	Amp-dependent synthetase and ligase
UM93_14915	ENOG4108RKS	Short-chain dehydrogenase reductase Sdr
UM93_14930	ENOG4105CSH	Transporter
UM93_14935	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
UM93_14960	ENOG4105E7W	lamb ycsf family protein
UM93_14965	ENOG4105P4J	Allophanate hydrolase, subunit 1
UM93_14975	ENOG4106BRA	Membrane
UM93_14985	ENOG4105BZP	glycoside hydrolase 15-related
UM93_15025	ENOG4105C7N	Xanthine uracil vitamin C permease
UM93_15030	ENOG4105FXM	Copper resistance protein
UM93_15060	ENOG4105ZXU	NLP P60 protein
UM93_15145	ENOG4105CG3	alpha amylase, catalytic region
UM93_15170	ENOG4105ETE	Transcriptional regulator (LacI family
UM93_15195	ENOG4105CJ1	ABC, transporter
UM93_15205	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
UM93_15210	ENOG4105ETE	Transcriptional regulator (LacI family
UM93_15225	ENOG4105EB1	binding-protein-dependent transport systems inner membrane Component
UM93_15235	ENOG4105D9R	oxidoreductase
UM93_15245	ENOG4105D2H	Uronic isomerase
UM93_15255	ENOG4105CXK	mandelate racemase muconate lactonizing
UM93_15275	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
UM93_15280	ENOG41080E2	ribosomal-protein-alanine acetyltransferase
UM93_15345	ENOG4105DTQ	mandelate racemase muconate lactonizing
UM93_15390	ENOG4107RCW	fructose-bisphosphate aldolase
UM93_15415	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
UM93_15420	ENOG4107QPI	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
UM93_15430	ENOG4105K4P	CoA-binding domain protein
UM93_15440	ENOG4105MSB	protein, conserved in bacteria
UM93_15450	ENOG4105CYW	agmatinase
UM93_15460	ENOG4108QYW	Bacterial hemolysins are exotoxins that attack blood cell membranes and cause cell rupture. Beta-hemolysin is a phospholipase C with specific activity toward sphingomyelins. Has a high specificity for sphingomyelin, hydrolyzes lysophosphatidylcholine at a much lower rate, but has no activity towards phosphatidylcholine, phosphatidylethanolamine, or phosphatidylserine (By similarity)
UM93_15470	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
UM93_15475	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
UM93_15520	ENOG4105CFH	Aspartokinase
UM93_15525	ENOG4108RVA	ribokinase
UM93_15555	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
UM93_15565	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
UM93_15590	ENOG41067D0	Antitoxin component of a toxin-antitoxin (TA) module. Upon expression in M.smegmatis neutralizes the effect of toxin RelE2
UM93_15600	ENOG4105CAT	Cytidine monophosphate kinase
UM93_15605	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
UM93_15635	ENOG4108V06	Glutathione peroxidase
UM93_15655	ENOG4105CPK	Glycosyl transferase (Group 1
UM93_15660	ENOG4108SHN	Glycosyl transferase, family 2
UM93_15695	ENOG4105C1G	acyl-Coa dehydrogenase
UM93_15700	ENOG410609C	Acyl carrier protein
UM93_15730	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
UM93_15740	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
UM93_15765	ENOG41061H0	Monooxygenase
UM93_15775	ENOG4107R9S	Malate synthase
UM93_15790	ENOG4105C1G	acyl-Coa dehydrogenase
UM93_15795	ENOG4105F35	Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine (By similarity)
UM93_15805	ENOG4106YT9	Enoyl-CoA hydratase
UM93_15810	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
UM93_15815	ENOG4106P55	Transcriptional regulator
UM93_15825	ENOG4105CSH	Transporter
UM93_15845	ENOG41082W1	Cupin 2, conserved barrel domain protein
UM93_15850	ENOG4105D22	carbon starvation protein
UM93_15875	ENOG4108ZGX	Histidine kinase
UM93_15880	ENOG4108S01	response regulator
UM93_15905	ENOG4108VC7	Protein of unknown function (DUF2587)
UM93_15925	ENOG4105C6E	dna polymerase iii
UM93_15930	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
UM93_15950	ENOG4107RPC	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
UM93_15955	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
UM93_15980	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
UM93_15985	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
UM93_16035	ENOG4105EB1	binding-protein-dependent transport systems inner membrane Component
UM93_16040	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
UM93_16050	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
UM93_16060	ENOG4105C84	Histidine ammonia-lyase
UM93_16095	ENOG4105CQB	FAD linked oxidase domain protein
UM93_16110	ENOG4108IJ9	(ABC) transporter
UM93_16120	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
UM93_16140	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
UM93_16195	ENOG4105VBF	alkaline shock protein
UM93_16230	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
UM93_16265	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
UM93_16275	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
UM93_16285	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
UM93_16295	ENOG4105BZU	Histidine kinase
UM93_16300	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
UM93_16320	ENOG4105VEQ	Cold shock protein
UM93_16330	ENOG4107R8H	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
UM93_16340	ENOG4105DR5	peptidase
UM93_16345	ENOG4105K4H	Nlp p60 protein
UM93_16370	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
UM93_16380	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
UM93_16390	ENOG4105EEM	helicase
UM93_16395	ENOG4105CDA	abc transporter atp-binding protein
UM93_16400	ENOG4105DRP	amino acid AbC transporter
UM93_16410	ENOG4105BZ1	(ABC) transporter
UM93_16435	ENOG4105CPQ	Dehydrogenase
UM93_16465	ENOG4105ECY	inositol monophosphatase
UM93_16480	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
UM93_16520	ENOG4105CJK	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity)
UM93_16525	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
UM93_16545	ENOG4105DH8	myo-inositol catabolism
UM93_16550	ENOG4105FDP	GntR family transcriptional regulator
UM93_16555	ENOG4105CK5	oxidoreductase
UM93_16565	ENOG41062B0	ABC transporter, permease
UM93_16570	ENOG4105C2J	ABC transporter
UM93_16610	ENOG4108JCI	Transcriptional regulator
UM93_16615	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
UM93_16625	ENOG4105C7K	acetolactate synthase
UM93_16635	ENOG4108UZX	fmn reductase
UM93_16640	ENOG4105Y3U	Transglycosylase-associated protein
UM93_16665	ENOG4106KNT	transcriptional regulator
UM93_16675	ENOG4105DTQ	mandelate racemase muconate lactonizing
UM93_16690	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
UM93_16695	ENOG4108JQ6	ABC transporter
UM93_16700	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
UM93_16710	ENOG4105DEF	Extracellular solute-binding protein, family 5
UM93_16725	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
UM93_16730	ENOG4106KNT	transcriptional regulator
UM93_16760	ENOG4105CP9	extracellular ligand-binding receptor
UM93_16765	ENOG4105C32	Amino acid ABC transporter (Permease)
UM93_16770	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
UM93_16775	ENOG4105C0Z	ABC transporter
UM93_16780	ENOG4108IV0	ABC, transporter
UM93_16795	ENOG4105DFW	ABC transporter
UM93_16800	ENOG4108HWW	ABC transporter
UM93_16820	ENOG4108Z0R	Transferase
UM93_16850	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
UM93_16855	ENOG4105BZU	Histidine kinase
UM93_16860	ENOG4105WH1	Two component transcriptional regulator luxr family